"Artifact, because...",sample,chr,pos,ref,alt,ann,Nr_Ref,Nr_Alt,DP,VAF,GATK,Platypus,VarScan,LoFreq,FreeBayes,SNVer,SAMtools,VarDict,Called,ESP6500,1000G,Cosmic,Cosmic_location,Cosmic_occurence,dbSNP (SNPs),dbSNP (SNVs),Clinically_flagged_dbSNP,ExAC,ClinVar (clinical),ClinVar (no impact),Provean Score,Prediction,SIFT Score,Prediction,BQ_REF,BQ_ALT
"low bq, bad alignment, low freq, many artifacts",UPN2_058,1,115256533,C,A,stop_gained(HIGH|NONSENSE|Gga/Tga|p.Gly60*/c.178G>T|189|NRAS|protein_coding|CODING|ENST00000369535|3|A),3390,40,3441,"0,0116245278",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,09","14,55"
"low bq, many samples",UPN2_015,1,115256541,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp57Val/c.170A>T|189|NRAS|protein_coding|CODING|ENST00000369535|3|A),1135,28,1163,"0,0240756664",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,07",Deleterious,0,Damaging,"27,97","15,14"
"low bq, many samples",UPN2_022,1,115256541,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp57Val/c.170A>T|189|NRAS|protein_coding|CODING|ENST00000369535|3|A),800,31,837,"0,037037037",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,07",Deleterious,0,Damaging,"28,33","15,65"
"low bq, many samples",UPN2_025,1,115256541,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp57Val/c.170A>T|189|NRAS|protein_coding|CODING|ENST00000369535|3|A),904,25,933,"0,026795284",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,07",Deleterious,0,Damaging,"28,61","15,96"
"low bq, many samples",UPN2_026,1,115256541,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp57Val/c.170A>T|189|NRAS|protein_coding|CODING|ENST00000369535|3|A),773,22,798,"0,0275689223",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,07",Deleterious,0,Damaging,"27,84","14,32"
"low bq, many samples",UPN2_027,1,115256541,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp57Val/c.170A>T|189|NRAS|protein_coding|CODING|ENST00000369535|3|A),1082,27,1112,"0,0242805755",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,07",Deleterious,0,Damaging,"28,17",15
"low bq, many samples",UPN2_028,1,115256541,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp57Val/c.170A>T|189|NRAS|protein_coding|CODING|ENST00000369535|3|A),785,20,812,"0,0246305419",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,07",Deleterious,0,Damaging,"28,26","16,65"
"low bq, many samples",UPN2_029,1,115256541,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp57Val/c.170A>T|189|NRAS|protein_coding|CODING|ENST00000369535|3|A),901,36,942,"0,0382165605",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,07",Deleterious,0,Damaging,"28,57","17,17"
"low bq, low freq, many artifacts, many samples",UPN2_030,1,115256541,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp57Val/c.170A>T|189|NRAS|protein_coding|CODING|ENST00000369535|3|A),1000,22,1026,"0,0214424951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,07",Deleterious,0,Damaging,"28,37","16,14"
"low bq, low freq, many artifacts, many samples",UPN2_035,1,115256541,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp57Val/c.170A>T|189|NRAS|protein_coding|CODING|ENST00000369535|3|A),1519,32,1558,"0,0205391528",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,07",Deleterious,0,Damaging,"28,28","18,03"
"low bq, many samples",UPN2_036,1,115256541,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp57Val/c.170A>T|189|NRAS|protein_coding|CODING|ENST00000369535|3|A),1669,51,1724,"0,0295823666",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,07",Deleterious,0,Damaging,"28,47","15,82"
"low bq, low freq, many artifacts, many samples",UPN2_037,1,115256541,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp57Val/c.170A>T|189|NRAS|protein_coding|CODING|ENST00000369535|3|A),1296,21,1327,"0,0158251696",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,07",Deleterious,0,Damaging,"28,14","15,81"
"low bq, low freq, many artifacts, many samples",UPN2_038,1,115256541,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp57Val/c.170A>T|189|NRAS|protein_coding|CODING|ENST00000369535|3|A),1535,22,1573,"0,013986014",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,07",Deleterious,0,Damaging,"28,27",15
"low bq, low freq, many artifacts, many samples",UPN2_008,1,115256541,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp57Val/c.170A>T|189|NRAS|protein_coding|CODING|ENST00000369535|3|A),1018,22,1042,"0,0211132438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,07",Deleterious,0,Damaging,"31,49","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_058,1,115256541,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp57Val/c.170A>T|189|NRAS|protein_coding|CODING|ENST00000369535|3|A),3339,71,3422,"0,0207481005",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,07",Deleterious,0,Damaging,"30,28","15,89"
"low bq, many samples",UPN2_040,1,115256541,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp57Val/c.170A>T|189|NRAS|protein_coding|CODING|ENST00000369535|3|A),1473,41,1518,"0,0270092227",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,07",Deleterious,0,Damaging,"28,06","15,63"
"low bq, many samples",UPN2_071,1,115256541,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp57Val/c.170A>T|189|NRAS|protein_coding|CODING|ENST00000369535|3|A),727,23,753,"0,0305444887",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,07",Deleterious,0,Damaging,"28,25","15,57"
"low bq, low freq, many artifacts, many samples",UPN2_075,1,115256541,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp57Val/c.170A>T|189|NRAS|protein_coding|CODING|ENST00000369535|3|A),1157,25,1189,"0,0210260723",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,07",Deleterious,0,Damaging,"28,31","15,24"
"low bq, many samples",UPN2_085,1,115256541,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp57Val/c.170A>T|189|NRAS|protein_coding|CODING|ENST00000369535|3|A),954,24,991,"0,0242179617",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,07",Deleterious,0,Damaging,"28,8","18,04"
"low bq, many samples",UPN2_087,1,115256541,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp57Val/c.170A>T|189|NRAS|protein_coding|CODING|ENST00000369535|3|A),1089,25,1126,"0,0222024867",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,07",Deleterious,0,Damaging,"27,85","14,52"
"inspected, bad alignment, many artifacts",UPN2_044,1,115258692,A,T,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp30Glu/c.90T>A|189|NRAS|protein_coding|CODING|ENST00000369535|2|T),5602,61,5704,"0,0106942496",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,"0,419",Tolerated,35,"35,33"
"inspected, bad alignment, many artifacts",UPN2_044,1,115258720,A,G,missense_variant(MODERATE|MISSENSE|aTc/aCc|p.Ile21Thr/c.62T>C|189|NRAS|protein_coding|CODING|ENST00000369535|2|G),5607,87,5703,"0,0152551289",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,0,Damaging,"34,98","34,09"
"inspected, bad alignment, many artifacts",UPN2_020,1,115258733,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser17Gly/c.49A>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),8854,91,8987,"0,0101257372",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,0,Damaging,"33,15","33,75"
"inspected, bad alignment, many artifacts",UPN2_041,1,115258733,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser17Gly/c.49A>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),14245,171,14483,"0,0118069461",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,0,Damaging,"33,37","32,59"
"inspected, bad alignment, many artifacts",UPN2_045,1,115258733,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser17Gly/c.49A>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),24602,256,24983,"0,0102469679",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,0,Damaging,"33,37","32,32"
"inspected, bad alignment, many artifacts",UPN2_032,1,115258733,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser17Gly/c.49A>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),6454,79,6554,"0,0120537077",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,0,Damaging,"33,13","33,24"
"inspected, bad alignment, many artifacts",UPN2_046,1,115258733,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser17Gly/c.49A>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),22460,251,22796,"0,0110107036",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,0,Damaging,"33,27","33,12"
"inspected, bad alignment, many artifacts",UPN2_049,1,115258733,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser17Gly/c.49A>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),22345,270,22702,"0,0118932253",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,0,Damaging,"33,45","32,97"
"inspected, bad alignment, many artifacts",UPN2_039,1,115258733,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser17Gly/c.49A>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),13181,144,13374,"0,0107671602",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,0,Damaging,"32,97","33,02"
"inspected, bad alignment, many artifacts",UPN2_053,1,115258733,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser17Gly/c.49A>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),23451,257,23807,"0,0107951443",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,0,Damaging,"33,39","33,12"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_059,1,115258741,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val14Gly/c.41T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),29195,473,29780,"0,015883143",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,26,Damaging,"26,63","14,96"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_060,1,115258741,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val14Gly/c.41T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),16877,245,17199,"0,0142450142",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,26,Damaging,"26,97","14,83"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,1,115258741,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val14Gly/c.41T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),14240,230,14535,"0,0158238734",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,26,Damaging,"26,64","15,2"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,1,115258741,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val14Gly/c.41T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),13452,241,13755,"0,0175209015",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,26,Damaging,"26,3","14,61"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,1,115258741,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val14Gly/c.41T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),14191,247,14510,"0,0170227429",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,26,Damaging,"26,68","14,68"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,1,115258741,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val14Gly/c.41T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),19089,338,19521,"0,0173146867",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,26,Damaging,"26,6","14,97"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_065,1,115258741,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val14Gly/c.41T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),19815,356,20267,"0,0175655006",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,26,Damaging,"26,73","15,08"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_066,1,115258741,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val14Gly/c.41T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),27479,437,28046,"0,0155815446",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,26,Damaging,"26,91","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_067,1,115258741,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val14Gly/c.41T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),24632,387,25115,"0,0154091181",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,26,Damaging,"27,11","14,96"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_068,1,115258741,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val14Gly/c.41T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),16764,329,17158,"0,019174729",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,26,Damaging,"26,23","14,58"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_069,1,115258741,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val14Gly/c.41T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),18141,358,18578,"0,0192701044",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,26,Damaging,"26,57","14,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_070,1,115258741,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val14Gly/c.41T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),12676,207,12938,"0,0159993817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,26,Damaging,"26,42","14,86"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,1,115258741,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val14Gly/c.41T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),11671,206,11951,"0,0172370513",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,26,Damaging,"26,56","14,93"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,1,115258741,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val14Gly/c.41T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),14555,283,14903,"0,0189894652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,26,Damaging,"26,54","14,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,1,115258741,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val14Gly/c.41T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),12126,186,12357,"0,0150521971",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,26,Damaging,"26,82","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_074,1,115258741,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val14Gly/c.41T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),11587,216,11846,"0,018234003",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,26,Damaging,"27,16","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_075,1,115258741,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val14Gly/c.41T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),18039,287,18388,"0,0156080052",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,26,Damaging,"27,07","15,04"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,1,115258741,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val14Gly/c.41T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),15972,285,16320,"0,0174632353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,26,Damaging,"26,32","14,61"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,1,115258741,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val14Gly/c.41T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),16669,310,17039,"0,018193556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,26,Damaging,"26,58","14,68"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,1,115258741,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val14Gly/c.41T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),15739,277,16094,"0,0172113831",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,26,Damaging,"26,35","14,92"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_079,1,115258741,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val14Gly/c.41T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),9917,177,10140,"0,0174556213",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,26,Damaging,"26,78","14,95"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,1,115258741,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val14Gly/c.41T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),16442,294,16814,"0,0174854288",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,26,Damaging,"26,54","15,05"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_081,1,115258741,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val14Gly/c.41T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),22485,369,22961,"0,0160707286",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,26,Damaging,"26,73","14,83"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_082,1,115258741,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val14Gly/c.41T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),23183,352,23652,"0,0148824624",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,26,Damaging,"26,89","14,89"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,1,115258741,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val14Gly/c.41T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),18188,327,18595,"0,0175853724",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,26,Damaging,"26,28","14,85"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,1,115258741,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val14Gly/c.41T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),21278,365,21728,"0,0167986009",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,26,Damaging,"26,14","15,27"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_085,1,115258741,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val14Gly/c.41T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),25810,419,26358,"0,015896502",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,26,Damaging,"26,58","15,33"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,1,115258741,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val14Gly/c.41T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),23752,464,24348,"0,0190570067",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,26,Damaging,"26,34","14,74"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_087,1,115258741,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val14Gly/c.41T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),21152,392,21651,"0,0181053993",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,26,Damaging,"26,54","14,88"
"low bq, low freq, many artifacts",UPN2_088,1,115258741,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val14Gly/c.41T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),15649,244,15966,"0,0152824753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,26,Damaging,"27,14","14,73"
"Hotspot, inspected, low freq, many artifacts",UPN2_049,1,115258744,C,A,missense_variant(MODERATE|MISSENSE|gGt/gTt|p.Gly13Val/c.38G>T|189|NRAS|protein_coding|CODING|ENST00000369535|2|A),22091,323,22697,"0,0142309556",0,0,0,0,1,0,0,1,2,NO,NO,COSM574,"adrenal_gland, central_nervous_system, haematopoietic_and_lymphoid_tissue, large_intestine, skin, soft_tissue","1, 1, 48, 4, 18, 1",NO,rs121434596,YES,NO,NO,NO,"-7,65",Deleterious,"0,025",Damaging,"34,8","28,67"
"low freq, many artifacts",UPN2_049,1,115258744,C,T,missense_variant(MODERATE|MISSENSE|gGt/gAt|p.Gly13Asp/c.38G>A|189|NRAS|protein_coding|CODING|ENST00000369535|2|T),22091,230,22697,"0,0101334978",0,0,0,0,0,0,0,1,1,NO,NO,COSM573,endometrium. haematopoietic_and_lymphoid_tissue. large_intestine. NS. skin. thyroid. upper_aerodigestive_tract,1. 217. 10. 278. 26. 1. 2,NO,rs121434596,YES,"8,24E-006",NO,NO,"-5,48",Deleterious,29,Damaging,"34,8","34,69"
"low bq, low freq, many artifacts, many samples",UPN2_059,1,115258756,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val9Gly/c.26T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),56968,1235,58597,"0,0210761643",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,47",Deleterious,0,Damaging,"27,05","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_060,1,115258756,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val9Gly/c.26T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),32938,676,33826,"0,0199846272",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,47",Deleterious,0,Damaging,"27,17","14,99"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,1,115258756,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val9Gly/c.26T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),27794,602,28593,"0,0210541042",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,47",Deleterious,0,Damaging,"26,87","14,72"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,1,115258756,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val9Gly/c.26T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),26313,582,27057,"0,0215101452",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,47",Deleterious,0,Damaging,"26,66","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_063,1,115258756,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val9Gly/c.26T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),27689,606,28530,"0,0212407992",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,47",Deleterious,0,Damaging,"27,09","14,55"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,1,115258756,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val9Gly/c.26T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),37312,835,38357,"0,0217691686",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,47",Deleterious,0,Damaging,"26,98","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_065,1,115258756,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val9Gly/c.26T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),38794,865,39877,"0,021691702",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,47",Deleterious,0,Damaging,"27,11","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_066,1,115258756,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val9Gly/c.26T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),53696,1131,55140,"0,0205114255",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,47",Deleterious,0,Damaging,"27,19","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_067,1,115258756,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val9Gly/c.26T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),48112,962,49362,"0,0194886755",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,47",Deleterious,0,Damaging,"27,37","14,8"
"low bq, bad alignment, many samples",UPN2_068,1,115258756,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val9Gly/c.26T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),32746,777,33712,"0,0230481728",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,47",Deleterious,0,Damaging,"26,68","14,8"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_069,1,115258756,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val9Gly/c.26T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),35552,774,36523,"0,0211921255",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,47",Deleterious,0,Damaging,"26,97","14,73"
"low bq, bad alignment, many samples",UPN2_070,1,115258756,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val9Gly/c.26T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),24714,579,25463,"0,022738876",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,47",Deleterious,0,Damaging,"26,77","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_071,1,115258756,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val9Gly/c.26T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),22822,511,23499,"0,0217456062",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,47",Deleterious,0,Damaging,"27,12","15,03"
"low bq, many samples",UPN2_072,1,115258756,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val9Gly/c.26T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),28458,650,29315,"0,022172949",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,47",Deleterious,0,Damaging,"27,03","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_073,1,115258756,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val9Gly/c.26T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),23661,497,24304,"0,0204493088",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,47",Deleterious,0,Damaging,"27,14","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_074,1,115258756,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val9Gly/c.26T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),22719,454,23285,"0,0194975306",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,47",Deleterious,0,Damaging,"27,21","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_075,1,115258756,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val9Gly/c.26T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),35284,695,36196,"0,0192010167",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,47",Deleterious,0,Damaging,"27,3","14,96"
"low bq, bad alignment, many samples",UPN2_076,1,115258756,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val9Gly/c.26T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),31165,779,32108,"0,0242618662",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,47",Deleterious,0,Damaging,"26,76","15,01"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,1,115258756,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val9Gly/c.26T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),32614,713,33545,"0,0212550306",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,47",Deleterious,0,Damaging,"26,89","15,06"
"low bq, bad alignment, many samples",UPN2_078,1,115258756,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val9Gly/c.26T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),30831,719,31705,"0,0226778111",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,47",Deleterious,0,Damaging,"26,68","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_079,1,115258756,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val9Gly/c.26T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),19466,400,19986,"0,0200140098",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,47",Deleterious,0,Damaging,"27,01","14,87"
"low bq, bad alignment, many samples",UPN2_080,1,115258756,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val9Gly/c.26T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),32114,779,33095,"0,0235382988",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,47",Deleterious,0,Damaging,"26,93","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_081,1,115258756,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val9Gly/c.26T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),43966,901,45125,"0,019966759",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,47",Deleterious,0,Damaging,"27,19","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_082,1,115258756,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val9Gly/c.26T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),45210,928,46414,"0,0199939673",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,47",Deleterious,0,Damaging,"27,19","14,93"
"low bq, bad alignment, many samples",UPN2_083,1,115258756,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val9Gly/c.26T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),35513,834,36576,"0,0228018373",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,47",Deleterious,0,Damaging,"26,64","14,96"
"low bq, bad alignment, many samples",UPN2_084,1,115258756,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val9Gly/c.26T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),41449,1001,42719,"0,0234321964",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,47",Deleterious,0,Damaging,"26,76","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_085,1,115258756,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val9Gly/c.26T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),50323,1085,51778,"0,0209548457",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,47",Deleterious,0,Damaging,"27,08","14,97"
"low bq, bad alignment, many samples",UPN2_086,1,115258756,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val9Gly/c.26T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),46455,1063,47786,"0,022245009",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,47",Deleterious,0,Damaging,"26,84","14,7"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_087,1,115258756,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val9Gly/c.26T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),41310,914,42465,"0,0215236077",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,47",Deleterious,0,Damaging,"26,99","14,96"
"low bq, low freq, many artifacts",UPN2_088,1,115258756,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val9Gly/c.26T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),30627,605,31418,"0,0192564772",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,47",Deleterious,0,Damaging,"27,33","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_068,1,115258759,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val8Gly/c.23T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),33153,387,33766,"0,0114612332",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,0,Damaging,"29,36","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_069,1,115258759,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val8Gly/c.23T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),35998,379,36583,"0,0103600033",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,0,Damaging,"29,59","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_076,1,115258759,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val8Gly/c.23T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),31621,363,32174,"0,0112824019",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,0,Damaging,"29,37","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_081,1,115258759,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val8Gly/c.23T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),44384,453,45201,"0,0100219022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,0,Damaging,"29,66","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_083,1,115258759,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val8Gly/c.23T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),36001,377,36642,"0,0102887397",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,0,Damaging,"29,32","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_086,1,115258759,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val8Gly/c.23T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),47031,545,47882,"0,0113821478",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,0,Damaging,"29,43","15,21"
"low bq, low freq, many artifacts",UPN2_087,1,115258759,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val8Gly/c.23T>G|189|NRAS|protein_coding|CODING|ENST00000369535|2|C),41852,438,42546,"0,0102947398",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,0,Damaging,"29,58","14,97"
"low bq, low freq, many artifacts",UPN2_041,1,115258794,A,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-13T>A|189|NRAS|protein_coding|CODING|ENST00000369535|2|T),14659,173,14908,"0,0116045076",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,19","23,08"
"low bq, low freq, many artifacts, many samples",UPN2_042,1,115258796,A,T,splice_region_variant(LOW|||c.-15T>A|189|NRAS|protein_coding|CODING|ENST00000369535|2|T),28504,305,28938,"0,0105397747",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,2","17,28"
"low bq, low freq, many artifacts, many samples",UPN2_043,1,115258796,A,T,splice_region_variant(LOW|||c.-15T>A|189|NRAS|protein_coding|CODING|ENST00000369535|2|T),17506,198,17769,"0,0111430019",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,32","17,48"
"low bq, low freq, many artifacts, many samples",UPN2_045,1,115258796,A,T,splice_region_variant(LOW|||c.-15T>A|189|NRAS|protein_coding|CODING|ENST00000369535|2|T),24101,260,24472,"0,0106243871",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,21","17,09"
"low bq, low freq, many artifacts, many samples",UPN2_047,1,115258796,A,T,splice_region_variant(LOW|||c.-15T>A|189|NRAS|protein_coding|CODING|ENST00000369535|2|T),34094,367,34605,"0,0106054038",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,14","16,58"
"low bq, low freq, many artifacts, many samples",UPN2_048,1,115258796,A,T,splice_region_variant(LOW|||c.-15T>A|189|NRAS|protein_coding|CODING|ENST00000369535|2|T),24230,247,24571,"0,0100525009",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,23","16,84"
"low bq, low freq, many artifacts, many samples",UPN2_049,1,115258796,A,T,splice_region_variant(LOW|||c.-15T>A|189|NRAS|protein_coding|CODING|ENST00000369535|2|T),21983,229,22316,"0,0102616956",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,24","17,08"
"low bq, low freq, many artifacts, many samples",UPN2_051,1,115258796,A,T,splice_region_variant(LOW|||c.-15T>A|189|NRAS|protein_coding|CODING|ENST00000369535|2|T),16649,172,16918,"0,0101666864",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,25","16,85"
"low bq, low freq, many artifacts, many samples",UPN2_057,1,115258796,A,T,splice_region_variant(LOW|||c.-15T>A|189|NRAS|protein_coding|CODING|ENST00000369535|2|T),23726,277,24113,"0,0114875793",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,26","17,32"
"low bq, low freq, many artifacts",UPN2_058,1,115258796,A,T,splice_region_variant(LOW|||c.-15T>A|189|NRAS|protein_coding|CODING|ENST00000369535|2|T),21302,269,21670,"0,0124134749",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,25","20,46"
"inspected, bad alignment, many artifacts",UPN2_044,1,115258797,A,G,splice_region_variant(LOW|||c.-16T>C|189|NRAS|protein_coding|CODING|ENST00000369535|2|G),5453,61,5589,"0,0109142959",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,,,,,"32,57","32,89"
"low bq, low freq, many artifacts, many samples",UPN2_041,1,115258797,A,T,splice_region_variant(LOW|||c.-16T>A|189|NRAS|protein_coding|CODING|ENST00000369535|2|T),13941,161,14169,"0,0113628344",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,76","15,42"
"low bq, low freq, many artifacts, many samples",UPN2_045,1,115258797,A,T,splice_region_variant(LOW|||c.-16T>A|189|NRAS|protein_coding|CODING|ENST00000369535|2|T),24049,262,24453,"0,0107144318",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,61","15,98"
"low bq, low freq, many artifacts, many samples",UPN2_046,1,115258797,A,T,splice_region_variant(LOW|||c.-16T>A|189|NRAS|protein_coding|CODING|ENST00000369535|2|T),21984,225,22338,"0,0100725222",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,5","17,21"
"low bq, low freq, many artifacts, many samples",UPN2_047,1,115258797,A,T,splice_region_variant(LOW|||c.-16T>A|189|NRAS|protein_coding|CODING|ENST00000369535|2|T),33990,371,34566,"0,0107330903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,6","16,87"
"low bq, low freq, many artifacts, many samples",UPN2_048,1,115258797,A,T,splice_region_variant(LOW|||c.-16T>A|189|NRAS|protein_coding|CODING|ENST00000369535|2|T),24153,263,24560,"0,0107084691",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,67","18,17"
"low bq, low freq, many artifacts, many samples",UPN2_049,1,115258797,A,T,splice_region_variant(LOW|||c.-16T>A|189|NRAS|protein_coding|CODING|ENST00000369535|2|T),21989,231,22309,"0,0103545654",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,65","15,73"
"low bq, low freq, many artifacts, many samples",UPN2_050,1,115258797,A,T,splice_region_variant(LOW|||c.-16T>A|189|NRAS|protein_coding|CODING|ENST00000369535|2|T),21753,246,22111,"0,011125684",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,54","16,4"
"low bq, low freq, many artifacts, many samples",UPN2_051,1,115258797,A,T,splice_region_variant(LOW|||c.-16T>A|189|NRAS|protein_coding|CODING|ENST00000369535|2|T),16642,182,16908,"0,0107641353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,78","16,93"
"low bq, low freq, many artifacts, many samples",UPN2_054,1,115258797,A,T,splice_region_variant(LOW|||c.-16T>A|189|NRAS|protein_coding|CODING|ENST00000369535|2|T),16600,184,16877,"0,0109024116",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,47","17,34"
"low bq, low freq, many artifacts, many samples",UPN2_055,1,115258797,A,T,splice_region_variant(LOW|||c.-16T>A|189|NRAS|protein_coding|CODING|ENST00000369535|2|T),25615,297,26024,"0,0114125423",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,62","16,43"
"low bq, low freq, many artifacts, many samples",UPN2_056,1,115258797,A,T,splice_region_variant(LOW|||c.-16T>A|189|NRAS|protein_coding|CODING|ENST00000369535|2|T),13347,144,13555,"0,0106233862",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,57","16,11"
"low bq, low freq, many artifacts, many samples",UPN2_057,1,115258797,A,T,splice_region_variant(LOW|||c.-16T>A|189|NRAS|protein_coding|CODING|ENST00000369535|2|T),23705,249,24080,"0,0103405316",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,66","16,01"
"low bq, low freq, many artifacts",UPN2_012,1,115258797,A,T,splice_region_variant(LOW|||c.-16T>A|189|NRAS|protein_coding|CODING|ENST00000369535|2|T),13145,134,13332,"0,0100510051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,47","16,35"
"inspected, low freq",UPN2_044,2,25457148,TTA,T,frameshift_variant+stop_lost(HIGH||taa/|p.Ter913fs/c.2737_2738delTA|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|T),2100,29,2140,"0,0135514019",0,0,0,1,1,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,,,,,"35,28",NA
"inspected, bad alignment, many artifacts",UPN2_069,2,25457191,C,T,missense_variant(MODERATE|MISSENSE|cGc/cAc|p.Arg899His/c.2696G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|T),1678,20,1701,"0,0117577895",0,0,0,0,1,0,0,1,2,NO,NO,COSM1583134,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-4,72",Deleterious,"0,002",Damaging,"34,9","35,6"
"inspected, low freq, no database, many artifacts",UPN2_061,2,25457201,G,A,missense_variant(MODERATE|MISSENSE|Cca/Tca|p.Pro896Ser/c.2686C>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|A),1949,20,1973,"0,0101368474",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,"0,015",Damaging,"34,69","28,75"
"low bq, low freq, many artifacts",UPN2_080,2,25457203,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val895Gly/c.2684T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),2600,27,2647,"0,0102002267",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,61",Deleterious,1,Damaging,"29,76","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,25457213,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser892Ala/c.2674T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),1358,23,1391,"0,016534867",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,04",Neutral,175,Tolerated,"29,67","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25457213,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser892Ala/c.2674T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),1766,22,1798,"0,0122358176",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,04",Neutral,175,Tolerated,"29,75",14
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25457213,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser892Ala/c.2674T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),2000,32,2039,"0,0156939676",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,04",Neutral,175,Tolerated,"29,7","15,78"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25457213,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser892Ala/c.2674T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),2454,39,2500,"0,0156",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,04",Neutral,175,Tolerated,"29,35","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25457213,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser892Ala/c.2674T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),2195,35,2244,"0,015597148",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,04",Neutral,175,Tolerated,"29,25","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25457213,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser892Ala/c.2674T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),1926,32,1973,"0,0162189559",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,04",Neutral,175,Tolerated,"29,58","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,25457213,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser892Ala/c.2674T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),1021,23,1046,"0,0219885277",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,04",Neutral,175,Tolerated,"29,88","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25457213,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser892Ala/c.2674T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),2392,37,2438,"0,0151763741",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,04",Neutral,175,Tolerated,"29,41","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25457213,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser892Ala/c.2674T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),2590,41,2644,"0,0155068079",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,04",Neutral,175,Tolerated,"29,46","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25457213,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser892Ala/c.2674T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),2065,37,2109,"0,0175438596",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,04",Neutral,175,Tolerated,"29,89","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25457213,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser892Ala/c.2674T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),2681,48,2733,"0,0175631175",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,04",Neutral,175,Tolerated,"29,78","15,56"
"low bq, many samples",UPN2_076,2,25457213,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser892Ala/c.2674T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),1656,39,1698,"0,0229681979",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,04",Neutral,175,Tolerated,"29,57","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25457213,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser892Ala/c.2674T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),1453,20,1478,"0,0135317997",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,04",Neutral,175,Tolerated,"28,97","16,3"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25457213,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser892Ala/c.2674T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),1771,24,1804,"0,0133037694",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,04",Neutral,175,Tolerated,"29,53","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25457213,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser892Ala/c.2674T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),1391,31,1431,"0,0216631726",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,04",Neutral,175,Tolerated,"29,87","15,58"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25457213,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser892Ala/c.2674T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),2757,36,2807,"0,0128250802",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,04",Neutral,175,Tolerated,"29,19","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25457213,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser892Ala/c.2674T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),3913,69,4001,"0,0172456886",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,04",Neutral,175,Tolerated,"29,67","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25457213,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser892Ala/c.2674T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),2490,36,2534,"0,0142067877",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,04",Neutral,175,Tolerated,"29,31","16,22"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25457213,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser892Ala/c.2674T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),2173,41,2221,"0,0184601531",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,04",Neutral,175,Tolerated,"29,26","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,25457213,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser892Ala/c.2674T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),1183,23,1212,"0,0189768977",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,04",Neutral,175,Tolerated,"29,26","14,3"
"low bq, low freq, many artifacts",UPN2_087,2,25457213,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser892Ala/c.2674T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),1823,31,1859,"0,0166756321",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,04",Neutral,175,Tolerated,"29,41",14
"inspected, bad alignment, many artifacts",UPN2_069,2,25457215,C,T,missense_variant(MODERATE|MISSENSE|cGg/cAg|p.Arg891Gln/c.2672G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|T),3310,39,3357,"0,0116175156",0,0,0,0,1,0,0,1,2,NO,NO,COSM5133340,large_intestine,1,NO,NO,NO,NO,NO,NO,"-3,18",Deleterious,"0,019",Damaging,"31,12","33,21"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25457226,T,G,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg887Ser/c.2661A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|G),4906,55,4988,"0,0110264635",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,42",Deleterious,1,Damaging,"30,44","15,76"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25457226,T,G,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg887Ser/c.2661A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|G),3919,41,3977,"0,0103092784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,42",Deleterious,1,Damaging,"30,47","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25457226,T,G,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg887Ser/c.2661A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|G),2751,32,2801,"0,0114244913",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,42",Deleterious,1,Damaging,"30,78",14
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25457226,T,G,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg887Ser/c.2661A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|G),2700,30,2733,"0,0109769484",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,42",Deleterious,1,Damaging,"30,57","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25457226,T,G,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg887Ser/c.2661A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|G),7463,77,7576,"0,0101636748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,42",Deleterious,1,Damaging,"30,46","14,18"
"low bq, low freq, many artifacts, many samples",UPN2_087,2,25457226,T,G,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg887Ser/c.2661A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|G),3425,36,3474,"0,0103626943",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,42",Deleterious,1,Damaging,"30,4","16,42"
"low bq, low freq, many artifacts",UPN2_088,2,25457226,T,G,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg887Ser/c.2661A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|G),2081,22,2113,"0,0104117369",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,42",Deleterious,1,Damaging,"30,46","14,32"
"low bq, low freq, many artifacts",UPN2_056,2,25457239,A,T,stop_gained(HIGH|NONSENSE|tTg/tAg|p.Leu883*/c.2648T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|T),7965,95,8106,"0,0117197138",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,61","22,79"
"inspected, low freq, no database, many artifacts",UPN2_068,2,25457239,A,T,stop_gained(HIGH|NONSENSE|tTg/tAg|p.Leu883*/c.2648T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|T),2149,25,2186,"0,0114364135",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,24","26,52"
"Hotspot, inspected, low freq, many artifacts",UPN2_111,2,25457242,C,T,missense_variant(MODERATE|MISSENSE|cGc/cAc|p.Arg882His/c.2645G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|T),8277,97,8388,"0,0115641392",0,0,0,0,1,1,0,1,3,"0,0581",NO,COSM52944,"breast, haematopoietic_and_lymphoid_tissue","1, 452",NO,rs147001633,NO,NA,NO,NO,"-4,72",Deleterious,"0,002",Damaging,"31,64","33,53"
"Hotspot, inspected, bad alignment, many artifacts",UPN2_076,2,25457243,G,A,missense_variant(MODERATE|MISSENSE|Cgc/Tgc|p.Arg882Cys/c.2644C>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|A),3156,40,3206,"0,0124766064",0,0,0,0,1,0,0,1,2,"0,0465",NO,COSM53042,"haematopoietic_and_lymphoid_tissue, prostate","191, 1",NO,rs377577594,NO,"0,0003624",NO,NO,"-7,55",Deleterious,0,Damaging,"32,54","34,15"
"Inspected, not in 2nd Illumina, many artifacts",UPN2_013,2,25457248,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met880Lys/c.2639T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|T),3443,52,3510,"0,0148148148",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,51",Deleterious,0,Damaging,"34,19","29,35"
"Inspected, not in 2nd Illumina, many artifacts",UPN2_006,2,25457249,T,C,missense_variant(MODERATE|MISSENSE|Atg/Gtg|p.Met880Val/c.2638A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),4537,56,4601,"0,0121712671",0,0,0,0,1,0,0,1,2,NO,NO,COSM120499,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,"1,65E-005",NO,NO,"-3,55",Deleterious,"0,002",Damaging,"33,17","34,41"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,25457257,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val877Gly/c.2630T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),2567,46,2632,"0,0174772036",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,61",Deleterious,0,Damaging,"31,13","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25457257,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val877Gly/c.2630T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),3300,45,3362,"0,0133848899",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,61",Deleterious,0,Damaging,"31,42","15,73"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25457257,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val877Gly/c.2630T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),3808,64,3904,"0,0163934426",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,61",Deleterious,0,Damaging,"31,29","15,39"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25457257,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val877Gly/c.2630T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),4593,68,4701,"0,0144650074",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,61",Deleterious,0,Damaging,"31,25","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25457257,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val877Gly/c.2630T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),4048,66,4153,"0,0158921262",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,61",Deleterious,0,Damaging,"31,2","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25457257,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val877Gly/c.2630T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),3577,68,3668,"0,0185387132",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,61",Deleterious,0,Damaging,"31,36","15,69"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,25457257,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val877Gly/c.2630T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),1543,34,1584,"0,0214646465",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,61",Deleterious,0,Damaging,"31,42","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25457257,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val877Gly/c.2630T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),2132,36,2186,"0,0164684355",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,61",Deleterious,0,Damaging,"30,95","15,31"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25457257,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val877Gly/c.2630T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),3291,55,3365,"0,0163447251",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,61",Deleterious,0,Damaging,"31,11","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,25457257,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val877Gly/c.2630T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),1947,27,1993,"0,013547416",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,61",Deleterious,0,Damaging,"31,32","15,89"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25457257,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val877Gly/c.2630T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),4550,68,4630,"0,0146868251",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,61",Deleterious,0,Damaging,"31,32","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25457257,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val877Gly/c.2630T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),4890,74,4991,"0,014826688",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,61",Deleterious,0,Damaging,"31,1","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25457257,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val877Gly/c.2630T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),3906,51,3976,"0,0128269618",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,61",Deleterious,0,Damaging,"31,17","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,25457257,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val877Gly/c.2630T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),1703,30,1743,"0,017211704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,61",Deleterious,0,Damaging,"31,4",14
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25457257,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val877Gly/c.2630T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),5038,78,5152,"0,0151397516",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,61",Deleterious,0,Damaging,"31,38","14,41"
"low bq, many samples",UPN2_076,2,25457257,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val877Gly/c.2630T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),3126,71,3210,"0,0221183801",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,61",Deleterious,0,Damaging,"31,14","15,73"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25457257,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val877Gly/c.2630T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),2736,54,2805,"0,0192513369",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,61",Deleterious,0,Damaging,"31,31","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25457257,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val877Gly/c.2630T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),3355,48,3430,"0,0139941691",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,61",Deleterious,0,Damaging,"31,21","15,6"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25457257,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val877Gly/c.2630T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),2676,43,2733,"0,0157336261",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,61",Deleterious,0,Damaging,"31,34","15,7"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25457257,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val877Gly/c.2630T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),5142,84,5249,"0,0160030482",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,61",Deleterious,0,Damaging,"30,9","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25457257,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val877Gly/c.2630T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),7402,128,7575,"0,0168976898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,61",Deleterious,0,Damaging,"31,31","15,65"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25457257,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val877Gly/c.2630T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),2543,33,2583,"0,012775842",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,61",Deleterious,0,Damaging,"31,19","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25457257,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val877Gly/c.2630T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),4671,78,4779,"0,0163214062",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,61",Deleterious,0,Damaging,"31,16","15,46"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25457257,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val877Gly/c.2630T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),4083,66,4162,"0,0158577607",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,61",Deleterious,0,Damaging,"30,92","15,8"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,25457257,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val877Gly/c.2630T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),2233,47,2294,"0,0204882302",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,61",Deleterious,0,Damaging,"31,19","16,17"
"low bq, low freq, many artifacts, many samples",UPN2_087,2,25457257,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val877Gly/c.2630T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),3405,52,3478,"0,0149511213",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,61",Deleterious,0,Damaging,"31,11","14,73"
"low bq, low freq, many artifacts",UPN2_088,2,25457257,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val877Gly/c.2630T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|C),2067,39,2116,"0,0184310019",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,61",Deleterious,0,Damaging,"31,43","14,33"
"Inspected, not in 2nd Illumina, many artifacts",UPN2_006,2,25457261,C,T,missense_variant(MODERATE|MISSENSE|Gac/Aac|p.Asp876Asn/c.2626G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|T),4546,50,4601,"0,0108672028",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,"0,029",Damaging,"33,32","30,68"
"inspected, bad alignment, many artifacts",UPN2_060,2,25457261,C,T,missense_variant(MODERATE|MISSENSE|Gac/Aac|p.Asp876Asn/c.2626G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|T),3323,38,3363,"0,011299435",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,"0,029",Damaging,"31,68","31,32"
"low bq, low freq, many artifacts",UPN2_061,2,25457264,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr875Pro/c.2623A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|G),3840,40,3904,"0,0102459016",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,68",Deleterious,1,Damaging,"31,94","18,88"
"low bq, low freq, many artifacts",UPN2_051,2,25457283,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe868Leu/c.2604T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|T),5989,62,6088,"0,0101839685",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,66",Deleterious,9,Damaging,"33,78","25,85"
"low bq, low freq, many artifacts, many samples",UPN2_032,2,25457284,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe868Tyr/c.2603T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|T),1710,20,1737,"0,0115141048",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,84",Deleterious,0,Damaging,"34,81","17,3"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,25457284,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe868Tyr/c.2603T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|23|T),7366,80,7486,"0,010686615",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,84",Deleterious,0,Damaging,"34,04","20,9"
"low freq, many artifacts, many samples",UPN2_006,2,25458628,GA,G,frameshift_variant(HIGH||ttt/|p.Pro849fs/c.2544delT|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),6442,67,6561,"0,0102118579",0,0,0,0,0,0,0,1,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,42",NA
"low bq, low freq, many artifacts, many samples",UPN2_001,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),15949,171,16181,"0,0105679501",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"28,07","15,56"
"low bq, low freq, many artifacts, many samples",UPN2_014,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),23353,398,23840,"0,0166946309",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"27,19","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_015,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),31844,600,32625,"0,0183908046",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"27,15","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_016,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),14721,247,15030,"0,0164337991",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"27,31","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_017,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),10588,209,10858,"0,0192484804",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"27,27","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_018,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),16723,274,17095,"0,0160280784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"27,22","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_019,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),16966,322,17352,"0,0185569387",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"27,11","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_020,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),14750,241,15065,"0,0159973448",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"27,25","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_021,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),17283,268,17648,"0,0151858568",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"27,27","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_002,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),21610,247,21963,"0,0112461868",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"27,92","15,45"
"low bq, low freq, many artifacts, many samples",UPN2_003,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),4214,50,4284,"0,0116713352",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"27,87","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_022,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),23001,410,23540,"0,0174171623",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"27,16","15,25"
"low bq, low freq, many artifacts, many samples",UPN2_023,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),25501,459,26090,"0,0175929475",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"27,16","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_041,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),31886,427,32526,"0,0131279592",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"28,05","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_024,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),11808,208,12089,"0,0172057242",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"27,3","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_025,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),29011,459,29648,"0,0154816514",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"27,21","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_026,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),27923,511,28565,"0,017889025",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"27,16","15,39"
"low bq, low freq, many artifacts, many samples",UPN2_004,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),6730,85,6844,"0,0124196376",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"28,04","15,58"
"low bq, low freq, many artifacts, many samples",UPN2_027,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),28533,536,29237,"0,0183329343",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"27,14","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_089,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),18487,302,18869,"0,0160050877",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"28,96","16,51"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),42008,637,42906,"0,0148464084",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"28,03","15,5"
"low bq, low freq, many artifacts, many samples",UPN2_028,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),23760,459,24328,"0,018867149",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"27,12","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),29026,400,29630,"0,0134998313",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"28,1","15,42"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),20579,327,21031,"0,0155484761",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"27,99","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_029,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),28666,530,29385,"0,0180364131",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"27,22","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_030,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),24826,396,25335,"0,0156305506",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"27,18","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_031,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),17647,339,18112,"0,0187168728",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"27,18","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_005,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),6888,79,6998,"0,0112889397",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"27,93","15,92"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),38625,574,39452,"0,0145493258",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"28,01","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_032,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),10600,194,10868,"0,0178505705",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"27,14","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),37806,624,38665,"0,0161386267",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,28,"15,73"
"low bq, low freq, many artifacts, many samples",UPN2_033,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),19404,313,19821,"0,0157913324",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"27,24","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_034,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),7309,139,7489,"0,0185605555",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"27,23","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),50622,733,51669,"0,0141864561",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"28,1","15,77"
"low bq, low freq, many artifacts, many samples",UPN2_048,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),42524,587,43365,"0,013536262",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"28,06","15,54"
"low bq, low freq, many artifacts, many samples",UPN2_035,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),26676,491,27302,"0,0179840305",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"27,26","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_036,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),43947,872,45077,"0,0193446769",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"27,17",15
"low bq, low freq, many artifacts, many samples",UPN2_006,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),12739,144,12933,"0,0111343076",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"28,04","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),45610,645,46494,"0,0138727578",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,28,"15,61"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),37713,533,38478,"0,0138520713",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"27,94","15,65"
"low bq, low freq, many artifacts, many samples",UPN2_037,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),44581,845,45673,"0,0185010838",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"27,09","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),29315,358,29863,"0,0119880789",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"28,1","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),30118,422,30767,"0,0137159944",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"27,9","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_038,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),42873,846,43946,"0,0192508988",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"27,16","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_039,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),36318,722,37262,"0,0193763083",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"27,07","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),37288,582,38056,"0,015293252",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"27,99","15,61"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),25996,396,26542,"0,0149197498",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"27,88","15,73"
"low bq, low freq, many artifacts, many samples",UPN2_007,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),47671,564,48481,"0,0116334234",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"27,99","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_008,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),62186,714,63210,"0,0112956811",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"27,93","15,48"
"low bq, low freq, many artifacts, many samples",UPN2_009,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),54895,622,55815,"0,0111439577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"27,98","15,72"
"low bq, low freq, many artifacts, many samples",UPN2_010,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),38047,476,38736,"0,0122883106",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"27,89","15,51"
"low bq, low freq, many artifacts, many samples",UPN2_011,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),44531,477,45247,"0,0105421354",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,28,"15,38"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),41993,642,42945,"0,0149493538",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"28,08","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_056,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),29290,438,29878,"0,0146596158",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"28,11","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_090,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),20433,344,20860,"0,0164908917",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"28,81","16,27"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),44810,621,45707,"0,0135865404",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"28,05","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),41248,603,42104,"0,0143216797",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"28,15","15,2"
"inspected, bad alignment, strandbias",UPN2_059,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),49291,1902,51422,"0,0369880596",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,"0,012",Damaging,"27,72","17,61"
"low bq, low freq, many artifacts, many samples",UPN2_012,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),26169,275,26573,"0,0103488503",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"28,04","15,48"
"inspected, bad alignment, strandbias",UPN2_060,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),33103,1258,34532,"0,036429978",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,"0,012",Damaging,"27,7","16,91"
"low bq, low freq, many artifacts, many samples",UPN2_040,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),12017,235,12328,"0,0190622972",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"27,27","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_013,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),12539,148,12757,"0,0116014737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"27,97","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_091,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),16905,276,17238,"0,0160111382",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"28,96","16,53"
"low bq, low freq, many artifacts, many samples",UPN2_092,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),14576,247,14861,"0,016620685",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"28,88","18,13"
"low bq, low freq, many artifacts, many samples",UPN2_093,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),17513,297,17910,"0,0165829146",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"28,97","15,8"
"inspected, bad alignment, strandbias",UPN2_061,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),40109,1661,41994,"0,0395532695",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,"0,012",Damaging,"27,72","17,91"
"inspected, bad alignment, strandbias",UPN2_062,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),38797,1696,40700,"0,0416707617",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,"0,012",Damaging,"27,7","17,58"
"inspected, bad alignment, strandbias",UPN2_063,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),40152,1568,41948,"0,0373796129",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,"0,012",Damaging,"27,74","17,94"
"inspected, bad alignment, strandbias",UPN2_064,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),57348,2299,59929,"0,0383620618",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,"0,012",Damaging,"27,74","17,69"
"inspected, bad alignment, strandbias",UPN2_065,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),44282,1744,46284,"0,0376804079",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,"0,012",Damaging,"27,73","17,51"
"inspected, bad alignment, strandbias",UPN2_066,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),56445,2261,59034,"0,0382999627",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,"0,012",Damaging,"27,72","17,37"
"inspected, bad alignment, strandbias",UPN2_067,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),56902,2202,59378,"0,037084442",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,"0,012",Damaging,"27,75","17,71"
"inspected, bad alignment, strandbias",UPN2_068,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),40465,1727,42421,"0,0407109686",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,"0,012",Damaging,"27,68","17,58"
"inspected, bad alignment, strandbias",UPN2_069,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),40800,1732,42787,"0,0404795849",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,"0,012",Damaging,"27,75","17,64"
"inspected, bad alignment, strandbias",UPN2_070,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),26673,1232,28056,"0,0439121756",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,"0,012",Damaging,"27,63","17,71"
"inspected, bad alignment, strandbias",UPN2_071,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),22182,889,23173,"0,0383636128",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,"0,012",Damaging,"27,8","18,09"
"inspected, bad alignment, strandbias",UPN2_072,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),33027,1323,34516,"0,0383300498",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,"0,012",Damaging,"27,79","17,87"
"inspected, bad alignment, strandbias",UPN2_073,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),25710,1031,26902,"0,0383242882",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,"0,012",Damaging,"27,73","17,43"
"inspected, bad alignment, strandbias",UPN2_074,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),26962,1076,28180,"0,0381831086",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,"0,012",Damaging,"27,68","17,7"
"inspected, bad alignment, strandbias",UPN2_075,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),34055,1357,35548,"0,0381737369",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,"0,012",Damaging,"27,72","17,95"
"inspected, bad alignment, strandbias",UPN2_076,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),30385,1296,31841,"0,0407022393",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,"0,012",Damaging,"27,67","17,66"
"inspected, bad alignment, strandbias",UPN2_077,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),40110,1699,42019,"0,0404340893",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,"0,012",Damaging,"27,64","17,55"
"inspected, bad alignment, strandbias",UPN2_078,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),31139,1298,32597,"0,0398196153",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,"0,012",Damaging,"27,63","17,58"
"inspected, bad alignment, strandbias",UPN2_079,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),19104,772,19951,"0,0386948023",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,"0,012",Damaging,"27,72","17,47"
"inspected, bad alignment, strandbias",UPN2_080,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),30624,1295,32118,"0,0403200697",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,"0,012",Damaging,"27,65","17,67"
"inspected, bad alignment, strandbias",UPN2_081,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),44166,1609,45990,"0,0349858665",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,"0,012",Damaging,"27,72","17,87"
"inspected, bad alignment, strandbias",UPN2_082,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),46815,1752,48830,"0,0358795822",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,"0,012",Damaging,"27,72","17,67"
"inspected, bad alignment, strandbias",UPN2_083,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),36678,1575,38409,"0,0410060142",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,"0,012",Damaging,"27,7","17,66"
"inspected, bad alignment, strandbias",UPN2_084,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),43742,1824,45777,"0,0398453372",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,"0,012",Damaging,"27,73","17,35"
"inspected, bad alignment, strandbias",UPN2_085,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),40842,1676,42711,"0,0392404767",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,"0,012",Damaging,"27,73","17,58"
"inspected, bad alignment, strandbias",UPN2_086,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),33913,1420,35480,"0,0400225479",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,"0,012",Damaging,"27,7","17,56"
"inspected, bad alignment, strandbias",UPN2_087,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),43424,1672,45369,"0,036853358",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,"0,012",Damaging,"27,74","17,53"
"inspected, bad alignment, strandbias",UPN2_088,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),33581,1295,35030,"0,0369683129",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,"0,012",Damaging,"27,74","17,46"
"low bq, low freq, many artifacts, many samples",UPN2_094,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),20935,369,21389,"0,0172518584",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"28,86","16,43"
"low bq, low freq, many artifacts, many samples",UPN2_095,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),21007,368,21467,"0,017142591",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"28,87","16,54"
"low bq, low freq, many artifacts, many samples",UPN2_096,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),18016,281,18387,"0,0152825366",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"28,94","16,25"
"low bq, low freq, many artifacts, many samples",UPN2_097,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),22071,348,22477,"0,0154824932",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"28,95","16,07"
"low bq, low freq, many artifacts, many samples",UPN2_098,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),19113,321,19526,"0,016439619",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"28,93","16,23"
"low bq, low freq, many artifacts, many samples",UPN2_099,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),9228,157,9424,"0,0166595925",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"28,79","16,04"
"low bq, low freq, many artifacts, many samples",UPN2_100,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),15751,229,16054,"0,0142643578",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"29,05","16,43"
"low bq, low freq, many artifacts, many samples",UPN2_101,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),20729,355,21195,"0,0167492333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"28,78","16,77"
"low bq, low freq, many artifacts, many samples",UPN2_102,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),19722,362,20201,"0,017919905",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"28,81","16,69"
"low bq, low freq, many artifacts, many samples",UPN2_103,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),16873,318,17256,"0,0184283727",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"28,71","15,97"
"low bq, low freq, many artifacts, many samples",UPN2_104,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),19944,325,20358,"0,0159642401",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"28,8","16,49"
"low bq, low freq, many artifacts, many samples",UPN2_105,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),19167,302,19523,"0,0154689341",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"28,85","16,47"
"low bq, low freq, many artifacts, many samples",UPN2_106,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),23509,380,23989,"0,0158405936",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"28,91","16,22"
"low bq, low freq, many artifacts, many samples",UPN2_107,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),29497,523,30129,"0,017358691",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"28,85","16,21"
"low bq, low freq, many artifacts, many samples",UPN2_108,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),24154,400,24648,"0,0162284972",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"28,93","16,28"
"low bq, low freq, many artifacts, many samples",UPN2_109,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),24591,463,25176,"0,0183905307",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"28,88","16,62"
"low bq, low freq, many artifacts, many samples",UPN2_110,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),24141,396,24657,"0,016060348",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"28,9","16,65"
"low bq, low freq, many artifacts",UPN2_111,2,25458636,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln846Pro/c.2537A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|G),22402,438,22929,"0,0191024467",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,12,Damaging,"28,84","16,28"
"low freq, many artifacts",UPN2_006,2,25458693,A,T,missense_variant(MODERATE|MISSENSE|tTc/tAc|p.Phe827Tyr/c.2480T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|22|T),12819,139,12997,"0,0106947757",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,115,Tolerated,"33,82","29,98"
"inspected, bad alignment, many artifacts",UPN2_041,2,25459804,C,T,splice_donor_variant+intron_variant(HIGH|||c.2478+1G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|T),1484,36,1525,"0,0236065574",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"1,65E-005",NO,NO,,,,,"35,45","35,39"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,25459829,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys818Trp/c.2454T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),4182,63,4258,"0,0147956787",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,33",Deleterious,1,Damaging,"28,53","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25459829,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys818Trp/c.2454T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),4742,70,4824,"0,0145107794",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,33",Deleterious,1,Damaging,"28,62","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25459829,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys818Trp/c.2454T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),4543,77,4640,"0,0165948276",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,33",Deleterious,1,Damaging,"28,4","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25459829,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys818Trp/c.2454T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),5147,94,5262,"0,0178639301",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,33",Deleterious,1,Damaging,"28,12","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25459829,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys818Trp/c.2454T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),5924,86,6039,"0,0142407683",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,33",Deleterious,1,Damaging,"28,35","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25459829,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys818Trp/c.2454T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),5719,86,5831,"0,0147487566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,33",Deleterious,1,Damaging,"28,45","15,52"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,25459829,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys818Trp/c.2454T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),3625,61,3703,"0,0164731299",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,33",Deleterious,1,Damaging,"28,34","15,25"
"low bq, low freq, many artifacts, many samples",UPN2_066,2,25459829,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys818Trp/c.2454T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),3005,43,3057,"0,0140660779",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,33",Deleterious,1,Damaging,"28,5","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_067,2,25459829,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys818Trp/c.2454T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),3340,51,3405,"0,0149779736",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,33",Deleterious,1,Damaging,"28,74","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25459829,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys818Trp/c.2454T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),3536,56,3610,"0,0155124654",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,33",Deleterious,1,Damaging,"28,08","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25459829,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys818Trp/c.2454T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),4478,78,4571,"0,0170640998",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,33",Deleterious,1,Damaging,"28,45","15,88"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,25459829,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys818Trp/c.2454T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),3309,59,3380,"0,0174556213",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,33",Deleterious,1,Damaging,"28,08","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25459829,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys818Trp/c.2454T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),5740,99,5871,"0,0168625447",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,33",Deleterious,1,Damaging,"28,24","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25459829,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys818Trp/c.2454T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),6410,108,6539,"0,0165162869",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,33",Deleterious,1,Damaging,"28,45","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25459829,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys818Trp/c.2454T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),3912,55,3983,"0,0138086869",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,33",Deleterious,1,Damaging,"29,03","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,25459829,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys818Trp/c.2454T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),2342,36,2383,"0,015107008",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,33",Deleterious,1,Damaging,"28,55","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25459829,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys818Trp/c.2454T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),6775,79,6876,"0,0114892379",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,33",Deleterious,1,Damaging,"28,85","16,53"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25459829,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys818Trp/c.2454T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),4371,75,4461,"0,0168123739",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,33",Deleterious,1,Damaging,"28,04","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25459829,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys818Trp/c.2454T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),4443,55,4510,"0,012195122",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,33",Deleterious,1,Damaging,"28,17","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25459829,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys818Trp/c.2454T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),5983,111,6123,"0,0181283684",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,33",Deleterious,1,Damaging,"28,13","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25459829,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys818Trp/c.2454T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),3426,62,3505,"0,0176890157",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,33",Deleterious,1,Damaging,"28,47","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25459829,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys818Trp/c.2454T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),5930,94,6050,"0,0155371901",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,33",Deleterious,1,Damaging,"28,36","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25459829,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys818Trp/c.2454T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),8903,135,9057,"0,0149055979",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,33",Deleterious,1,Damaging,"28,35","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25459829,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys818Trp/c.2454T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),4180,74,4272,"0,0173220974",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,33",Deleterious,1,Damaging,"28,56","16,55"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25459829,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys818Trp/c.2454T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),5932,99,6051,"0,0163609321",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,33",Deleterious,1,Damaging,"28,15","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25459829,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys818Trp/c.2454T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),5314,103,5440,"0,0189338235",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,33",Deleterious,1,Damaging,"28,27","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,25459829,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys818Trp/c.2454T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),3116,52,3183,"0,0163367892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,33",Deleterious,1,Damaging,"28,27","16,5"
"low bq, low freq, many artifacts, many samples",UPN2_086,2,25459829,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys818Trp/c.2454T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),2285,41,2340,"0,0175213675",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,33",Deleterious,1,Damaging,"28,29","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_087,2,25459829,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys818Trp/c.2454T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),5311,93,5431,"0,0171239182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,33",Deleterious,1,Damaging,"28,21","15,3"
"low bq, low freq, many artifacts",UPN2_088,2,25459829,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys818Trp/c.2454T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),3865,58,3938,"0,0147282885",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,33",Deleterious,1,Damaging,"28,78","14,93"
"inspected, bad alignment, many artifacts",UPN2_044,2,25459852,C,T,missense_variant(MODERATE|MISSENSE|Gat/Aat|p.Asp811Asn/c.2431G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|T),3521,55,3581,"0,0153588383",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,87",Deleterious,"0,105",Tolerated,"34,67","34,89"
"inspected, bad alignment, many artifacts",UPN2_041,2,25459869,A,T,stop_gained(HIGH|NONSENSE|tTg/tAg|p.Leu805*/c.2414T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|T),1466,54,1524,"0,0354330709",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,84","34,11"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25459870,A,C,missense_variant(MODERATE|MISSENSE|Ttg/Gtg|p.Leu805Val/c.2413T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),5174,59,5260,"0,01121673",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,271,Tolerated,"29,52","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,25459870,A,C,missense_variant(MODERATE|MISSENSE|Ttg/Gtg|p.Leu805Val/c.2413T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),3648,38,3696,"0,0102813853",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,271,Tolerated,"30,02","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_066,2,25459870,A,C,missense_variant(MODERATE|MISSENSE|Ttg/Gtg|p.Leu805Val/c.2413T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),3002,36,3057,"0,0117762512",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,271,Tolerated,"29,83","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_067,2,25459870,A,C,missense_variant(MODERATE|MISSENSE|Ttg/Gtg|p.Leu805Val/c.2413T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),3354,44,3405,"0,0129221733",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,271,Tolerated,30,"14,95"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25459870,A,C,missense_variant(MODERATE|MISSENSE|Ttg/Gtg|p.Leu805Val/c.2413T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),3553,42,3608,"0,0116407982",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,271,Tolerated,"29,57","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,25459870,A,C,missense_variant(MODERATE|MISSENSE|Ttg/Gtg|p.Leu805Val/c.2413T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),3317,50,3376,"0,0148104265",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,271,Tolerated,"29,43","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25459870,A,C,missense_variant(MODERATE|MISSENSE|Ttg/Gtg|p.Leu805Val/c.2413T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),5791,60,5869,"0,0102232067",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,271,Tolerated,"29,65","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25459870,A,C,missense_variant(MODERATE|MISSENSE|Ttg/Gtg|p.Leu805Val/c.2413T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),6439,76,6539,"0,0116225723",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,271,Tolerated,"29,92","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25459870,A,C,missense_variant(MODERATE|MISSENSE|Ttg/Gtg|p.Leu805Val/c.2413T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),4444,49,4508,"0,0108695652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,271,Tolerated,"29,62","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25459870,A,C,missense_variant(MODERATE|MISSENSE|Ttg/Gtg|p.Leu805Val/c.2413T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),6028,78,6120,"0,012745098",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,271,Tolerated,"29,54","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25459870,A,C,missense_variant(MODERATE|MISSENSE|Ttg/Gtg|p.Leu805Val/c.2413T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),5970,61,6049,"0,0100843115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,271,Tolerated,"29,74","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25459870,A,C,missense_variant(MODERATE|MISSENSE|Ttg/Gtg|p.Leu805Val/c.2413T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),5342,69,5438,"0,0126884884",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,271,Tolerated,"29,53","15,64"
"low bq, low freq, many artifacts",UPN2_087,2,25459870,A,C,missense_variant(MODERATE|MISSENSE|Ttg/Gtg|p.Leu805Val/c.2413T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|21|C),5337,69,5422,"0,0127259314",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,271,Tolerated,"29,68","15,03"
"low freq, many artifacts",UPN2_057,2,25461999,C,A,missense_variant(MODERATE|MISSENSE|aGg/aTg|p.Arg803Met/c.2408G>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|A),7172,77,7259,"0,0106075217",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,12,Damaging,"34,72","31,51"
"inspected, bad alignment, many artifacts",UPN2_044,2,25462014,A,G,missense_variant(MODERATE|MISSENSE|cTt/cCt|p.Leu798Pro/c.2393T>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2349,25,2377,"0,010517459",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,4",Deleterious,0,Damaging,"33,94","33,88"
inspected,UPN2_103,2,25462016,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn797Lys/c.2391C>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|T),4114,256,4379,"0,0584608358",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,69",Deleterious,0,Damaging,"34,9","34,91"
"inspected, bad alignment, many artifacts",UPN2_041,2,25462016,GT,G,frameshift_variant(HIGH||aac/|p.Asn797fs/c.2390delA|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),1799,30,1858,"0,016146394",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,NA,NA,NA,NA,"34,12",NA
"low bq, low freq, many artifacts",UPN2_072,2,25462026,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe794Cys/c.2381T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2370,32,2407,"0,0132945575",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,28",Deleterious,0,Damaging,"31,49",15
"Not in 2nd Illumina, bad alignment, many artifacts",UPN2_006,2,25462039,T,A,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg790Trp/c.2368A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|A),2068,29,2105,"0,0137767221",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,58",Deleterious,0,Damaging,"32,62","28,14"
"low bq, low freq, many artifacts",UPN2_064,2,25462045,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala788Pro/c.2362G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2440,28,2471,"0,0113314448",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,77",Deleterious,3,Damaging,30,"15,04"
"low bq, low freq, many artifacts",UPN2_077,2,25462045,C,T,missense_variant(MODERATE|MISSENSE|Gca/Aca|p.Ala788Thr/c.2362G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|T),2545,33,2601,"0,0126874279",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,54,Tolerated,"30,25","24,18"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_002,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),9312,115,9476,"0,0121359223",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"26,96","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_041,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),3579,53,3662,"0,0144729656",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"27,16","16,6"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_004,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),1671,23,1706,"0,0134818288",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"26,83","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_089,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),8224,96,8359,"0,0114846273",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"28,71","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),26033,305,26535,"0,0114942529",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"27,18","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),16604,233,16989,"0,0137147566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"27,19","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),4552,74,4687,"0,0157883508",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"27,07","15,2"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),23804,295,24371,"0,0121045505",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"26,94","14,67"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),19227,258,19648,"0,0131311075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"26,93","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),27003,348,27581,"0,0126173815",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"27,17","15,25"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_048,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),10695,125,10920,"0,0114468864",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"26,97","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_006,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),4112,47,4183,"0,0112359551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"27,21","15,3"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),16207,190,16544,"0,0114845261",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"27,11","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),19689,222,20093,"0,0110486239",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"27,25",16
"low bq, low freq, many artifacts, many samples",UPN2_051,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),17442,213,17777,"0,0119817742",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"27,2","15,11"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),17044,208,17392,"0,0119595216",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"26,95","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),22203,280,22663,"0,0123549398",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"27,04","14,51"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),12421,143,12705,"0,0112554113",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"26,9","14,73"
"low freq, many artifacts, many samples",UPN2_008,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),32066,411,32676,"0,0125780389",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,27,"14,98"
"low bq, low freq, many artifacts, many samples",UPN2_009,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),25422,293,25931,"0,0112992172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"27,21","14,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_010,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),13731,158,13983,"0,011299435",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"26,95","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_011,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),16272,179,16525,"0,0108320726",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"27,18","16,17"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),25305,279,25824,"0,0108039033",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"27,1","14,9"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),7394,80,7545,"0,0106030484",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"26,98","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_090,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),6833,80,6933,"0,0115390163",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"29,18","15,73"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),13981,181,14319,"0,0126405475",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"27,13","15,62"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),11577,135,11810,"0,0114309907",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"27,35","14,86"
"low bq, bad alignment, many samples",UPN2_059,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2054,137,2200,"0,0622727273",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"26,53","15,85"
"low bq, low freq, many artifacts, many samples",UPN2_012,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),10575,110,10764,"0,0102192493",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"27,18","14,29"
"low bq, bad alignment, many samples",UPN2_060,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2810,142,2973,"0,0477632022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"26,77","15,46"
"low bq, low freq, many artifacts, many samples",UPN2_091,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),6838,101,6973,"0,01448444",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"29,09","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_092,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),3202,42,3254,"0,0129071911",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"29,33","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_093,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),4011,48,4081,"0,0117618231",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"29,3","15,12"
"low bq, bad alignment, many samples",UPN2_061,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),4118,252,4391,"0,0573901161",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"26,62","15,68"
"low bq, bad alignment, many samples",UPN2_062,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),3563,193,3781,"0,0510446972",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"26,2","16,46"
"low bq, bad alignment, many samples",UPN2_063,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),3167,196,3387,"0,05786832",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"26,7","14,87"
"low bq, bad alignment, many samples",UPN2_064,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2339,130,2480,"0,0524193548",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"26,61","14,68"
"low bq, bad alignment, many samples",UPN2_065,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2161,127,2312,"0,0549307958",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"26,74","15,35"
"low bq, bad alignment, many samples",UPN2_066,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),821,44,874,"0,0503432494",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"26,18","15,8"
"low bq, bad alignment, many samples",UPN2_067,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),953,57,1014,"0,0562130178",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"26,74","15,21"
"low bq, bad alignment, many samples",UPN2_068,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),1624,109,1741,"0,0626076967",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"26,51","14,78"
"low bq, bad alignment, many samples",UPN2_069,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2665,200,2886,"0,0693000693",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"26,48","15,44"
"low bq, bad alignment, many samples",UPN2_070,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),1770,121,1912,"0,0632845188",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"26,64","15,85"
"low bq, bad alignment, many samples",UPN2_071,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),4456,252,4735,"0,0532206969",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"26,48","15,71"
"low bq, bad alignment, many samples",UPN2_072,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),4453,271,4746,"0,0571007164",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"26,64","15,46"
"low bq, bad alignment, many samples",UPN2_073,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2671,145,2839,"0,0510743219",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"26,64","15,32"
"low bq, bad alignment, many samples",UPN2_074,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),1184,76,1267,"0,0599842147",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"26,93","15,74"
"low bq, bad alignment, many samples",UPN2_075,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),4154,222,4405,"0,0503972758",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"26,93","16,54"
"low bq, bad alignment, many samples",UPN2_076,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2368,147,2538,"0,0579196217",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"26,18","15,96"
"low bq, bad alignment, many samples",UPN2_077,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2457,137,2613,"0,0524301569",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"26,17","15,77"
"low bq, bad alignment, many samples",UPN2_078,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),3032,173,3216,"0,0537935323",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"26,34","15,24"
"low bq, bad alignment, many samples",UPN2_079,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2137,106,2259,"0,0469234174",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"26,37","16,31"
"low bq, bad alignment, many samples",UPN2_080,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),3933,215,4180,"0,0514354067",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"26,44","15,4"
"low bq, bad alignment, many samples",UPN2_081,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),6408,342,6777,"0,0504648074",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"26,69","15,49"
"low bq, bad alignment, many samples",UPN2_082,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2151,96,2271,"0,0422721268",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"26,73","15,74"
"low bq, bad alignment, many samples",UPN2_083,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),3675,219,3921,"0,0558530987",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"26,53","16,15"
"low bq, bad alignment, many samples",UPN2_084,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2880,205,3099,"0,0661503711",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"26,43","15,37"
"low bq, bad alignment, many samples",UPN2_085,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),1803,108,1921,"0,0562207184",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"26,44","15,52"
"low bq, bad alignment, many samples",UPN2_086,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),799,49,854,"0,0573770492",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"26,14","15,51"
"low bq, bad alignment, many samples",UPN2_087,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2245,136,2396,"0,0567612688",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"26,45","15,4"
"low bq, many samples",UPN2_088,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),1906,108,2030,"0,0532019704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"27,25","15,42"
"low bq, low freq, many artifacts, many samples",UPN2_094,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),10476,149,10667,"0,0139683135",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"29,03","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_095,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),9572,131,9736,"0,0134552177",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"28,78","15,34"
"low bq, low freq, many artifacts, many samples",UPN2_096,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),10833,154,11036,"0,0139543313",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"29,01","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_097,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),12599,172,12821,"0,0134154902",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"29,16","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_098,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),7643,114,7792,"0,0146303901",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"29,28","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_099,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),4828,65,4921,"0,0132086974",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"29,04","14,2"
"low bq, low freq, many artifacts, many samples",UPN2_100,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),8482,99,8623,"0,0114809231",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"29,14","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_101,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),7681,105,7811,"0,013442581",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"28,78","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_103,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),8544,97,8686,"0,0111673958",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"28,76","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_104,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),10085,138,10264,"0,0134450507",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"28,91","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_105,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),8415,100,8540,"0,0117096019",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"28,96","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_106,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),11923,156,12141,"0,012849024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"29,16","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_107,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),13882,157,14109,"0,011127649",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"29,1","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_108,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),12984,192,13219,"0,014524548",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"29,37","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_109,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),11578,176,11822,"0,0148874979",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"28,72","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_110,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),12990,190,13215,"0,0143776012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"28,95","15,09"
"low bq, low freq, many artifacts",UPN2_111,2,25462051,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser786Ala/c.2356T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),9455,138,9636,"0,0143212951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,2,Damaging,"28,79","14,51"
"low bq, bad alignment, many samples",UPN2_059,2,25462053,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val785Gly/c.2354T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2120,51,2200,"0,0231818182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,44",Deleterious,85,Tolerated,"26,44","14,9"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_060,2,25462053,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val785Gly/c.2354T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2900,53,2975,"0,0178151261",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,44",Deleterious,85,Tolerated,"26,99","15,7"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,2,25462053,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val785Gly/c.2354T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),4269,93,4394,"0,0211652253",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,44",Deleterious,85,Tolerated,"26,49","15,7"
"low bq, bad alignment, many samples",UPN2_062,2,25462053,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val785Gly/c.2354T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),3652,93,3783,"0,0245836638",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,44",Deleterious,85,Tolerated,"26,36","14,85"
"low bq, bad alignment, many samples",UPN2_063,2,25462053,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val785Gly/c.2354T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),3274,87,3388,"0,0256788666",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,44",Deleterious,85,Tolerated,"26,86","15,16"
"low bq, bad alignment, many samples",UPN2_064,2,25462053,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val785Gly/c.2354T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2385,66,2474,"0,0266774454",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,44",Deleterious,85,Tolerated,"26,59","14,91"
"low bq, bad alignment, many samples",UPN2_065,2,25462053,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val785Gly/c.2354T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2211,64,2314,"0,0276577355",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,44",Deleterious,85,Tolerated,"26,71","14,11"
"low bq, bad alignment, many samples",UPN2_066,2,25462053,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val785Gly/c.2354T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),839,25,876,"0,0285388128",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,44",Deleterious,85,Tolerated,"26,59","14,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_068,2,25462053,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val785Gly/c.2354T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),1695,32,1741,"0,0183802412",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,44",Deleterious,85,Tolerated,"26,18",14
"low bq, bad alignment, many samples",UPN2_069,2,25462053,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val785Gly/c.2354T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2792,66,2887,"0,0228611015",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,44",Deleterious,85,Tolerated,"26,22","14,74"
"low bq, bad alignment, many samples",UPN2_070,2,25462053,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val785Gly/c.2354T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),1837,59,1912,"0,0308577406",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,44",Deleterious,85,Tolerated,"26,31","15,63"
"low bq, bad alignment, many samples",UPN2_071,2,25462053,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val785Gly/c.2354T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),4561,115,4736,"0,0242820946",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,44",Deleterious,85,Tolerated,"26,46","15,43"
"low bq, bad alignment, many samples",UPN2_072,2,25462053,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val785Gly/c.2354T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),4579,110,4745,"0,0231822972",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,44",Deleterious,85,Tolerated,"26,54","14,62"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,2,25462053,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val785Gly/c.2354T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2760,56,2839,"0,0197252554",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,44",Deleterious,85,Tolerated,"26,63","14,32"
"low bq, bad alignment, many samples",UPN2_074,2,25462053,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val785Gly/c.2354T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),1224,33,1267,"0,0260457774",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,44",Deleterious,85,Tolerated,"26,63","15,61"
"low bq, bad alignment, many samples",UPN2_075,2,25462053,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val785Gly/c.2354T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),4270,99,4406,"0,02246936",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,44",Deleterious,85,Tolerated,"26,95","14,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,2,25462053,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val785Gly/c.2354T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2462,52,2537,"0,0204966496",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,44",Deleterious,85,Tolerated,"25,98","14,13"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,2,25462053,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val785Gly/c.2354T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2530,55,2615,"0,0210325048",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,44",Deleterious,85,Tolerated,"26,01","14,56"
"low bq, bad alignment, many samples",UPN2_078,2,25462053,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val785Gly/c.2354T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),3102,88,3218,"0,0273461778",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,44",Deleterious,85,Tolerated,"26,23","14,47"
"low bq, bad alignment, many samples",UPN2_079,2,25462053,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val785Gly/c.2354T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2192,51,2260,"0,0225663717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,44",Deleterious,85,Tolerated,"26,46","14,8"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,2,25462053,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val785Gly/c.2354T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),4068,83,4182,"0,0198469632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,44",Deleterious,85,Tolerated,"26,57","14,55"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_081,2,25462053,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val785Gly/c.2354T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),6576,137,6778,"0,0202124521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,44",Deleterious,85,Tolerated,"26,66","14,77"
"low bq, bad alignment, many samples",UPN2_082,2,25462053,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val785Gly/c.2354T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2201,53,2272,"0,0233274648",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,44",Deleterious,85,Tolerated,"26,73","15,91"
"low bq, bad alignment, many samples",UPN2_083,2,25462053,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val785Gly/c.2354T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),3797,87,3923,"0,0221769054",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,44",Deleterious,85,Tolerated,"26,39","14,15"
"low bq, bad alignment, many samples",UPN2_084,2,25462053,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val785Gly/c.2354T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2974,78,3100,"0,0251612903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,44",Deleterious,85,Tolerated,"26,46","14,91"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_085,2,25462053,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val785Gly/c.2354T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),1864,42,1922,"0,0218522373",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,44",Deleterious,85,Tolerated,"26,24","14,81"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_087,2,25462053,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val785Gly/c.2354T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2322,47,2396,"0,0196160267",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,44",Deleterious,85,Tolerated,"26,37","14,53"
low bq,UPN2_088,2,25462053,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val785Gly/c.2354T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),1959,47,2032,"0,0231299213",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,44",Deleterious,85,Tolerated,"27,09","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,25462053,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val785Glu/c.2354T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|T),22241,227,22647,"0,0100234027",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"27,79","19,38"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,25462053,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val785Glu/c.2354T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|T),14083,151,14324,"0,0105417481",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"28,02","20,76"
"low bq, bad alignment, many samples",UPN2_086,2,25462053,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val785Glu/c.2354T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|T),815,20,855,"0,0233918129",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"26,46","23,45"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,25462055,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu784Asp/c.2352A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2165,29,2206,"0,0131459655",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,05",Neutral,298,Tolerated,"30,03","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25462055,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu784Asp/c.2352A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2931,38,2979,"0,0127559584",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,05",Neutral,298,Tolerated,"29,91",14
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25462055,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu784Asp/c.2352A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),4303,58,4399,"0,0131848147",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,05",Neutral,298,Tolerated,"29,68","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25462055,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu784Asp/c.2352A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),3703,60,3793,"0,0158186132",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,05",Neutral,298,Tolerated,"29,66","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25462055,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu784Asp/c.2352A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),3340,37,3392,"0,0109080189",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,05",Neutral,298,Tolerated,"29,82","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25462055,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu784Asp/c.2352A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2433,26,2476,"0,0105008078",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,05",Neutral,298,Tolerated,"29,99","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,25462055,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu784Asp/c.2352A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2279,24,2318,"0,0103537532",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,05",Neutral,298,Tolerated,"29,73","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25462055,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu784Asp/c.2352A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2836,37,2890,"0,0128027682",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,05",Neutral,298,Tolerated,"29,45","15,41"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,25462055,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu784Asp/c.2352A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),1867,27,1914,"0,0141065831",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,05",Neutral,298,Tolerated,"29,27","16,37"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25462055,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu784Asp/c.2352A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),4652,58,4741,"0,012233706",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,05",Neutral,298,Tolerated,"29,53","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25462055,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu784Asp/c.2352A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),4664,60,4749,"0,0126342388",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,05",Neutral,298,Tolerated,"29,6","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25462055,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu784Asp/c.2352A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2785,39,2847,"0,0136986301",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,05",Neutral,298,Tolerated,"29,78","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25462055,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu784Asp/c.2352A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),4337,54,4413,"0,0122365738",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,05",Neutral,298,Tolerated,"30,06","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25462055,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu784Asp/c.2352A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2503,34,2542,"0,013375295",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,05",Neutral,298,Tolerated,"29,12","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25462055,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu784Asp/c.2352A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2557,38,2617,"0,0145204433",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,05",Neutral,298,Tolerated,"29,26","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25462055,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu784Asp/c.2352A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),3160,43,3222,"0,013345748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,05",Neutral,298,Tolerated,"29,55","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25462055,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu784Asp/c.2352A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2209,35,2261,"0,0154798762",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,05",Neutral,298,Tolerated,"29,71","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25462055,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu784Asp/c.2352A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),4098,52,4183,"0,0124312694",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,05",Neutral,298,Tolerated,"29,59","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25462055,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu784Asp/c.2352A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),6650,88,6787,"0,0129659643",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,05",Neutral,298,Tolerated,"29,78","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25462055,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu784Asp/c.2352A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2242,24,2276,"0,0105448155",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,05",Neutral,298,Tolerated,"29,89","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25462055,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu784Asp/c.2352A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),3865,40,3924,"0,0101936799",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,05",Neutral,298,Tolerated,"29,73",14
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25462055,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu784Asp/c.2352A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),3041,40,3102,"0,0128949065",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,05",Neutral,298,Tolerated,"29,4","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,25462055,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu784Asp/c.2352A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),1874,24,1922,"0,0124869927",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,05",Neutral,298,Tolerated,"29,66","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_087,2,25462055,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu784Asp/c.2352A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2340,30,2399,"0,0125052105",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,05",Neutral,298,Tolerated,"29,64",14
"low bq, low freq, many artifacts",UPN2_088,2,25462055,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu784Asp/c.2352A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),1996,22,2033,"0,0108214461",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,05",Neutral,298,Tolerated,"29,99","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25462056,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu784Ala/c.2351A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2933,35,2979,"0,011748909",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,43",Deleterious,56,Tolerated,"30,43","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25462056,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu784Ala/c.2351A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2839,33,2889,"0,0114226376",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,43",Deleterious,56,Tolerated,"30,2",14
"low bq, low freq, many artifacts, many samples",UPN2_070,2,25462056,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu784Ala/c.2351A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),1876,21,1914,"0,0109717868",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,43",Deleterious,56,Tolerated,"29,69",14
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25462056,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu784Ala/c.2351A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),3177,37,3223,"0,0114799876",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,43",Deleterious,56,Tolerated,"30,03","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25462056,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu784Ala/c.2351A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),3869,46,3925,"0,0117197452",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,43",Deleterious,56,Tolerated,"30,13","15,11"
"low bq, low freq, many artifacts",UPN2_084,2,25462056,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu784Ala/c.2351A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),3055,35,3102,"0,0112830432",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,43",Deleterious,56,Tolerated,"29,91",14
"inspected, bad alignment, many artifacts",UPN2_068,2,25462057,C,T,missense_variant(MODERATE|MISSENSE|Gaa/Aaa|p.Glu784Lys/c.2350G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|T),1713,24,1742,"0,0137772675",0,0,0,0,1,0,0,1,2,NO,NO,COSM4768020,biliary_tract,1,NO,NO,NO,NO,NO,NO,"0,17",Neutral,"0,493",Tolerated,"32,2","30,96"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25462058,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys783Asn/c.2349A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),4329,47,4400,"0,0106818182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,98",Neutral,346,Tolerated,"30,94","14,15"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25462058,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys783Asn/c.2349A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),3720,39,3794,"0,0102793885",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,98",Neutral,346,Tolerated,"30,56","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,25462058,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys783Asn/c.2349A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),1868,26,1914,"0,013584117",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,98",Neutral,346,Tolerated,"30,57",15
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25462058,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys783Asn/c.2349A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),4116,49,4183,"0,0117140808",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,98",Neutral,346,Tolerated,"30,8","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25462058,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys783Asn/c.2349A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),6661,73,6789,"0,0107526882",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,98",Neutral,346,Tolerated,"30,91","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25462058,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys783Asn/c.2349A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2235,25,2276,"0,0109841828",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,98",Neutral,346,Tolerated,"30,81","16,68"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25462058,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys783Asn/c.2349A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),3864,41,3924,"0,0104485219",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,98",Neutral,346,Tolerated,"30,78","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25462058,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys783Asn/c.2349A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),3047,38,3102,"0,0122501612",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,98",Neutral,346,Tolerated,"30,63","14,92"
"low bq, low freq, many artifacts",UPN2_085,2,25462058,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys783Asn/c.2349A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),1884,22,1923,"0,0114404576",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,98",Neutral,346,Tolerated,"30,69","16,59"
"low bq, low freq, many artifacts",UPN2_077,2,25462059,T,G,missense_variant(MODERATE|MISSENSE|aAa/aCa|p.Lys783Thr/c.2348A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2577,29,2618,"0,0110771581",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,39",Tolerated,"30,43",14
"inspected, bad alignment, many artifacts",UPN2_090,2,25462060,T,C,missense_variant(MODERATE|MISSENSE|Aaa/Gaa|p.Lys783Glu/c.2347A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),6836,83,6944,"0,011952765",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,"0,696",Tolerated,"33,82","31,55"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25462064,A,C,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp781Glu/c.2343T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),3719,48,3793,"0,0126548906",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,1,Damaging,"27,94","16,21"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25462064,A,C,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp781Glu/c.2343T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),3335,35,3393,"0,0103153551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,1,Damaging,"28,21","16,66"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25462064,A,C,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp781Glu/c.2343T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),1708,23,1742,"0,0132032147",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,1,Damaging,"27,62",14
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25462064,A,C,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp781Glu/c.2343T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2826,42,2891,"0,014527845",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,1,Damaging,"28,03","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,25462064,A,C,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp781Glu/c.2343T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),1878,20,1913,"0,0104547831",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,1,Damaging,"27,49","15,3"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25462064,A,C,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp781Glu/c.2343T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),4665,56,4752,"0,0117845118",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,1,Damaging,"27,99","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25462064,A,C,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp781Glu/c.2343T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2803,31,2849,"0,0108810109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,1,Damaging,"28,29",14
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25462064,A,C,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp781Glu/c.2343T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2494,29,2544,"0,0113993711",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,1,Damaging,"27,71","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25462064,A,C,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp781Glu/c.2343T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),3159,40,3222,"0,0124146493",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,1,Damaging,"27,82","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25462064,A,C,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp781Glu/c.2343T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2202,28,2261,"0,0123839009",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,1,Damaging,"28,23","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25462064,A,C,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp781Glu/c.2343T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2230,27,2275,"0,0118681319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,1,Damaging,"28,09",14
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25462064,A,C,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp781Glu/c.2343T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),3857,43,3924,"0,0109582059",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,1,Damaging,"27,99","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25462064,A,C,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp781Glu/c.2343T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),3052,38,3102,"0,0122501612",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,1,Damaging,"27,8",15
"low bq, low freq, many artifacts, many samples",UPN2_085,2,25462064,A,C,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp781Glu/c.2343T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),1889,23,1920,"0,0119791667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,1,Damaging,"27,84","15,13"
"low bq, low freq, many artifacts",UPN2_087,2,25462064,A,C,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp781Glu/c.2343T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2368,24,2399,"0,0100041684",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,1,Damaging,"28,24","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25462065,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp781Ala/c.2342A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2897,39,2979,"0,0130916415",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,52",Deleterious,1,Damaging,"28,94","15,31"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25462065,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp781Ala/c.2342A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),4327,56,4398,"0,0127330605",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,52",Deleterious,1,Damaging,"28,71","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25462065,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp781Ala/c.2342A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),3326,43,3392,"0,0126768868",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,52",Deleterious,1,Damaging,"28,9",14
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25462065,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp781Ala/c.2342A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2438,30,2478,"0,0121065375",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,52",Deleterious,1,Damaging,"28,68",14
"low bq, low freq, many artifacts, many samples",UPN2_065,2,25462065,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp781Ala/c.2342A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2276,36,2320,"0,0155172414",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,52",Deleterious,1,Damaging,29,14
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25462065,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp781Ala/c.2342A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),1711,27,1741,"0,0155083285",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,52",Deleterious,1,Damaging,"28,41","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25462065,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp781Ala/c.2342A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2832,41,2892,"0,0141770401",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,52",Deleterious,1,Damaging,"28,54","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,25462065,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp781Ala/c.2342A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),1859,35,1913,"0,0182958704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,52",Deleterious,1,Damaging,"28,53","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25462065,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp781Ala/c.2342A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),4640,70,4736,"0,0147804054",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,52",Deleterious,1,Damaging,"28,76","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25462065,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp781Ala/c.2342A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),4656,62,4751,"0,0130498842",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,52",Deleterious,1,Damaging,"28,61","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25462065,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp781Ala/c.2342A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2796,41,2849,"0,0143910144",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,52",Deleterious,1,Damaging,"29,01","15,34"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,25462065,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp781Ala/c.2342A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),1231,25,1267,"0,0197316496",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,52",Deleterious,1,Damaging,"29,34",14
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25462065,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp781Ala/c.2342A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),4344,60,4418,"0,0135808058",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,52",Deleterious,1,Damaging,"29,09","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25462065,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp781Ala/c.2342A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2486,43,2544,"0,0169025157",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,52",Deleterious,1,Damaging,"28,49",14
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25462065,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp781Ala/c.2342A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2572,31,2619,"0,0118365788",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,52",Deleterious,1,Damaging,"28,43",14
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25462065,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp781Ala/c.2342A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),3172,33,3221,"0,0102452654",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,52",Deleterious,1,Damaging,"28,41","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25462065,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp781Ala/c.2342A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2210,31,2260,"0,0137168142",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,52",Deleterious,1,Damaging,"28,94","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25462065,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp781Ala/c.2342A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),6643,102,6783,"0,015037594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,52",Deleterious,1,Damaging,"29,15","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25462065,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp781Ala/c.2342A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2237,23,2275,"0,0101098901",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,52",Deleterious,1,Damaging,"28,45","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25462065,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp781Ala/c.2342A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),3861,49,3924,"0,0124872579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,52",Deleterious,1,Damaging,"28,75","15,65"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25462065,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp781Ala/c.2342A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),3039,45,3101,"0,0145114479",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,52",Deleterious,1,Damaging,"28,3",14
"low bq, low freq, many artifacts, many samples",UPN2_085,2,25462065,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp781Ala/c.2342A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),1884,23,1920,"0,0119791667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,52",Deleterious,1,Damaging,"28,82","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_087,2,25462065,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp781Ala/c.2342A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2357,27,2398,"0,0112593828",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,52",Deleterious,1,Damaging,"29,09","14,48"
"low bq, low freq, many artifacts",UPN2_088,2,25462065,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp781Ala/c.2342A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2000,27,2031,"0,0132939439",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,52",Deleterious,1,Damaging,"29,25","15,63"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_059,2,25462068,A,C,missense_variant(MODERATE|MISSENSE|aTt/aGt|p.Ile780Ser/c.2339T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2153,35,2208,"0,0158514493",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,53",Deleterious,0,Damaging,"26,45","17,26"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_060,2,25462068,A,C,missense_variant(MODERATE|MISSENSE|aTt/aGt|p.Ile780Ser/c.2339T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2923,44,2979,"0,0147700571",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,53",Deleterious,0,Damaging,"26,76","14,16"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,2,25462068,A,C,missense_variant(MODERATE|MISSENSE|aTt/aGt|p.Ile780Ser/c.2339T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),4295,74,4398,"0,0168258299",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,53",Deleterious,0,Damaging,"26,45","15,22"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,2,25462068,A,C,missense_variant(MODERATE|MISSENSE|aTt/aGt|p.Ile780Ser/c.2339T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),3692,75,3795,"0,0197628458",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,53",Deleterious,0,Damaging,"25,97","15,17"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,2,25462068,A,C,missense_variant(MODERATE|MISSENSE|aTt/aGt|p.Ile780Ser/c.2339T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),3307,51,3393,"0,0150309461",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,53",Deleterious,0,Damaging,"26,57",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,2,25462068,A,C,missense_variant(MODERATE|MISSENSE|aTt/aGt|p.Ile780Ser/c.2339T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2409,49,2479,"0,0197660347",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,53",Deleterious,0,Damaging,"26,7","14,14"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_065,2,25462068,A,C,missense_variant(MODERATE|MISSENSE|aTt/aGt|p.Ile780Ser/c.2339T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2260,35,2319,"0,0150927124",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,53",Deleterious,0,Damaging,"26,42","14,37"
"low bq, many samples",UPN2_066,2,25462068,A,C,missense_variant(MODERATE|MISSENSE|aTt/aGt|p.Ile780Ser/c.2339T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),847,20,875,"0,0228571429",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,53",Deleterious,0,Damaging,"27,05",15
"low bq, bad alignment, many samples",UPN2_067,2,25462068,A,C,missense_variant(MODERATE|MISSENSE|aTt/aGt|p.Ile780Ser/c.2339T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),986,24,1017,"0,0235988201",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,53",Deleterious,0,Damaging,"26,8",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_068,2,25462068,A,C,missense_variant(MODERATE|MISSENSE|aTt/aGt|p.Ile780Ser/c.2339T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),1698,31,1742,"0,0177956372",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,53",Deleterious,0,Damaging,"25,66",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_069,2,25462068,A,C,missense_variant(MODERATE|MISSENSE|aTt/aGt|p.Ile780Ser/c.2339T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2810,60,2892,"0,020746888",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,53",Deleterious,0,Damaging,"25,92","14,77"
"low bq, bad alignment, many samples",UPN2_070,2,25462068,A,C,missense_variant(MODERATE|MISSENSE|aTt/aGt|p.Ile780Ser/c.2339T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),1860,43,1914,"0,0224660397",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,53",Deleterious,0,Damaging,"25,8",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,2,25462068,A,C,missense_variant(MODERATE|MISSENSE|aTt/aGt|p.Ile780Ser/c.2339T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),4616,83,4736,"0,0175253378",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,53",Deleterious,0,Damaging,"26,43","14,16"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,2,25462068,A,C,missense_variant(MODERATE|MISSENSE|aTt/aGt|p.Ile780Ser/c.2339T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),4634,91,4751,"0,0191538623",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,53",Deleterious,0,Damaging,"26,5","15,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,2,25462068,A,C,missense_variant(MODERATE|MISSENSE|aTt/aGt|p.Ile780Ser/c.2339T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2768,48,2849,"0,0168480168",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,53",Deleterious,0,Damaging,"26,65","14,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,2,25462068,A,C,missense_variant(MODERATE|MISSENSE|aTt/aGt|p.Ile780Ser/c.2339T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),1240,23,1267,"0,0181531176",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,53",Deleterious,0,Damaging,"26,68","14,78"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_075,2,25462068,A,C,missense_variant(MODERATE|MISSENSE|aTt/aGt|p.Ile780Ser/c.2339T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),4311,69,4417,"0,0156214625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,53",Deleterious,0,Damaging,"26,97","15,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,2,25462068,A,C,missense_variant(MODERATE|MISSENSE|aTt/aGt|p.Ile780Ser/c.2339T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2485,43,2545,"0,0168958743",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,53",Deleterious,0,Damaging,"25,94","14,3"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,2,25462068,A,C,missense_variant(MODERATE|MISSENSE|aTt/aGt|p.Ile780Ser/c.2339T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2545,54,2619,"0,0206185567",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,53",Deleterious,0,Damaging,"26,05","14,7"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,2,25462068,A,C,missense_variant(MODERATE|MISSENSE|aTt/aGt|p.Ile780Ser/c.2339T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),3135,63,3220,"0,0195652174",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,53",Deleterious,0,Damaging,"26,02","14,21"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_079,2,25462068,A,C,missense_variant(MODERATE|MISSENSE|aTt/aGt|p.Ile780Ser/c.2339T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2204,41,2260,"0,0181415929",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,53",Deleterious,0,Damaging,"26,39","14,98"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,2,25462068,A,C,missense_variant(MODERATE|MISSENSE|aTt/aGt|p.Ile780Ser/c.2339T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),4093,68,4183,"0,0162562754",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,53",Deleterious,0,Damaging,"26,43","14,37"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_081,2,25462068,A,C,missense_variant(MODERATE|MISSENSE|aTt/aGt|p.Ile780Ser/c.2339T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),6617,112,6783,"0,0165118679",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,53",Deleterious,0,Damaging,"26,64","14,49"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_082,2,25462068,A,C,missense_variant(MODERATE|MISSENSE|aTt/aGt|p.Ile780Ser/c.2339T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2218,35,2275,"0,0153846154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,53",Deleterious,0,Damaging,"26,81","14,74"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,2,25462068,A,C,missense_variant(MODERATE|MISSENSE|aTt/aGt|p.Ile780Ser/c.2339T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),3809,65,3924,"0,0165647299",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,53",Deleterious,0,Damaging,"26,32","14,71"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,2,25462068,A,C,missense_variant(MODERATE|MISSENSE|aTt/aGt|p.Ile780Ser/c.2339T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),3010,65,3099,"0,0209745079",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,53",Deleterious,0,Damaging,"25,82","14,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_085,2,25462068,A,C,missense_variant(MODERATE|MISSENSE|aTt/aGt|p.Ile780Ser/c.2339T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),1872,36,1920,"0,01875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,53",Deleterious,0,Damaging,"26,46","15,33"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_087,2,25462068,A,C,missense_variant(MODERATE|MISSENSE|aTt/aGt|p.Ile780Ser/c.2339T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2342,29,2399,"0,0120883702",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,53",Deleterious,0,Damaging,"26,36","15,62"
"low bq, bad alignment, low freq, many artifacts",UPN2_088,2,25462068,A,C,missense_variant(MODERATE|MISSENSE|aTt/aGt|p.Ile780Ser/c.2339T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),1971,38,2031,"0,0187099951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,53",Deleterious,0,Damaging,"26,88","15,87"
"inspected, bad alignment, many artifacts",UPN2_099,2,25462068,A,G,missense_variant(MODERATE|MISSENSE|aTt/aCt|p.Ile780Thr/c.2339T>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),4820,67,4921,"0,0136151189",0,0,0,0,1,1,0,1,3,"0,0116",NO,COSM1583121,haematopoietic_and_lymphoid_tissue,2,NO,rs370751539,NO,NO,NO,NO,"-4,4",Deleterious,0,Damaging,"29,88","33,04"
"low bq, low freq, many artifacts",UPN2_049,2,25462068,A,T,missense_variant(MODERATE|MISSENSE|aTt/aAt|p.Ile780Asn/c.2339T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|T),16316,166,16587,"0,0100078375",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,0,Damaging,"28,35","20,33"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,25462071,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met779Arg/c.2336T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2172,25,2208,"0,0113224638",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,52",Deleterious,3,Damaging,"29,25","16,28"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25462071,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met779Arg/c.2336T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),4314,61,4399,"0,0138667879",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,52",Deleterious,3,Damaging,"28,91","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25462071,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met779Arg/c.2336T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),3732,46,3796,"0,012118019",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,52",Deleterious,3,Damaging,"28,8","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25462071,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met779Arg/c.2336T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),3337,36,3392,"0,0106132075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,52",Deleterious,3,Damaging,"29,3","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25462071,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met779Arg/c.2336T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2431,28,2479,"0,011294877",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,52",Deleterious,3,Damaging,"29,23","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,25462071,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met779Arg/c.2336T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2274,26,2317,"0,011221407",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,52",Deleterious,3,Damaging,"29,36","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25462071,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met779Arg/c.2336T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),1707,20,1740,"0,0114942529",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,52",Deleterious,3,Damaging,"28,58",14
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25462071,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met779Arg/c.2336T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2832,43,2892,"0,014868603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,52",Deleterious,3,Damaging,"28,68","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,25462071,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met779Arg/c.2336T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),1881,22,1914,"0,0114942529",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,52",Deleterious,3,Damaging,"28,35","16,82"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25462071,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met779Arg/c.2336T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),4644,58,4736,"0,0122466216",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,52",Deleterious,3,Damaging,"28,95",14
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25462071,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met779Arg/c.2336T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),4668,53,4753,"0,0111508521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,52",Deleterious,3,Damaging,"28,91","15,34"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25462071,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met779Arg/c.2336T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2794,30,2849,"0,0105300105",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,52",Deleterious,3,Damaging,"29,32","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25462071,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met779Arg/c.2336T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2497,26,2545,"0,01021611",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,52",Deleterious,3,Damaging,"28,46","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25462071,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met779Arg/c.2336T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2569,30,2619,"0,0114547537",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,52",Deleterious,3,Damaging,"28,65","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25462071,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met779Arg/c.2336T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),3161,38,3221,"0,0117975784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,52",Deleterious,3,Damaging,"28,96","14,18"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25462071,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met779Arg/c.2336T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),4122,44,4184,"0,0105162524",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,52",Deleterious,3,Damaging,"28,91","16,32"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25462071,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met779Arg/c.2336T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),6663,72,6782,"0,0106163374",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,52",Deleterious,3,Damaging,"29,41","14,18"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25462071,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met779Arg/c.2336T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2227,34,2274,"0,0149516271",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,52",Deleterious,3,Damaging,"29,13","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25462071,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met779Arg/c.2336T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),3854,52,3923,"0,0132551619",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,52",Deleterious,3,Damaging,"29,07","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25462071,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met779Arg/c.2336T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),3037,42,3098,"0,0135571336",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,52",Deleterious,3,Damaging,"28,86",14
"low bq, low freq, many artifacts, many samples",UPN2_085,2,25462071,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met779Arg/c.2336T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),1874,32,1920,"0,0166666667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,52",Deleterious,3,Damaging,"29,03","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_087,2,25462071,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met779Arg/c.2336T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2347,29,2398,"0,0120934112",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,52",Deleterious,3,Damaging,"29,11","15,45"
"low bq, low freq, many artifacts",UPN2_088,2,25462071,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met779Arg/c.2336T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),1993,24,2031,"0,011816839",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,52",Deleterious,3,Damaging,"29,58","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,25462074,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val778Gly/c.2333T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2163,35,2208,"0,0158514493",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"27,88",14
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25462074,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val778Gly/c.2333T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2903,51,2979,"0,0171198389",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"27,9","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25462074,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val778Gly/c.2333T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),4251,91,4397,"0,020695929",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"27,78","14,22"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,2,25462074,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val778Gly/c.2333T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),3694,70,3794,"0,0184501845",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"26,97","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25462074,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val778Gly/c.2333T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),3296,51,3388,"0,0150531287",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"27,56","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25462074,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val778Gly/c.2333T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2422,39,2478,"0,0157384988",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"27,85","15,82"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,25462074,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val778Gly/c.2333T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2269,37,2317,"0,0159689253",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"27,89",14
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25462074,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val778Gly/c.2333T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),1694,25,1739,"0,0143760782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"27,48","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25462074,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val778Gly/c.2333T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2829,47,2892,"0,0162517289",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"27,22","14,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_070,2,25462074,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val778Gly/c.2333T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),1861,40,1913,"0,0209095661",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"26,94","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25462074,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val778Gly/c.2333T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),4617,74,4736,"0,015625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"27,55","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25462074,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val778Gly/c.2333T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),4622,76,4751,"0,0159966323",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"27,22","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,25462074,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val778Gly/c.2333T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),1234,20,1265,"0,0158102767",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"27,9","20,3"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25462074,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val778Gly/c.2333T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),4306,59,4417,"0,0133574825",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"27,78","15,34"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,2,25462074,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val778Gly/c.2333T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2470,50,2545,"0,0196463654",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"26,91","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25462074,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val778Gly/c.2333T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2546,40,2615,"0,0152963671",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"27,4","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25462074,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val778Gly/c.2333T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),3137,54,3220,"0,0167701863",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"27,45","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25462074,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val778Gly/c.2333T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2210,28,2260,"0,0123893805",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"27,69","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25462074,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val778Gly/c.2333T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),4098,59,4183,"0,0141047095",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"27,41",14
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25462074,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val778Gly/c.2333T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),6618,106,6780,"0,0156342183",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"27,71","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25462074,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val778Gly/c.2333T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2207,40,2274,"0,0175901495",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"27,99","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25462074,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val778Gly/c.2333T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),3826,66,3923,"0,0168238593",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"27,37","15,68"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25462074,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val778Gly/c.2333T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),3011,62,3098,"0,0200129116",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"27,34","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,25462074,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val778Gly/c.2333T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),1864,38,1920,"0,0197916667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"27,42","16,05"
"low bq, low freq, many artifacts, many samples",UPN2_087,2,25462074,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val778Gly/c.2333T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),2332,45,2397,"0,0187734668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"27,77","15,56"
"low bq, low freq, many artifacts",UPN2_088,2,25462074,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val778Gly/c.2333T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|C),1987,25,2031,"0,0123092073",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"28,03","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_041,2,25462074,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val778Glu/c.2333T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|T),3604,40,3677,"0,0108784335",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,62",Deleterious,2,Damaging,"28,38","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,25462074,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val778Glu/c.2333T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|T),26010,302,26584,"0,0113602167",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,62",Deleterious,2,Damaging,"28,68","20,25"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,25462074,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val778Glu/c.2333T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|T),16680,209,17021,"0,0122789495",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,62",Deleterious,2,Damaging,"28,63","18,26"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,25462074,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val778Glu/c.2333T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|T),4608,48,4696,"0,0102214651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,62",Deleterious,2,Damaging,"28,59","16,35"
"low bq, low freq, many artifacts, many samples",UPN2_005,2,25462074,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val778Glu/c.2333T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|T),2949,32,3001,"0,0106631123",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,62",Deleterious,2,Damaging,"28,06","17,06"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,25462074,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val778Glu/c.2333T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|T),23887,332,24433,"0,0135881799",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,62",Deleterious,2,Damaging,"28,49","20,5"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,25462074,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val778Glu/c.2333T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|T),27036,312,27641,"0,01128758",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,62",Deleterious,2,Damaging,"28,53","19,36"
"inspected, bad alignment, many artifacts",UPN2_048,2,25462074,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val778Glu/c.2333T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|T),10637,213,10941,"0,0194680559",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,62",Deleterious,"0,002",Damaging,"28,39","25,07"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,25462074,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val778Glu/c.2333T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|T),16220,175,16589,"0,0105491591",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,62",Deleterious,2,Damaging,"28,39","17,68"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,25462074,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val778Glu/c.2333T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|T),19729,250,20152,"0,0124057166",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,62",Deleterious,2,Damaging,"28,49","18,39"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,25462074,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val778Glu/c.2333T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|T),17468,203,17818,"0,0113929734",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,62",Deleterious,2,Damaging,"28,75","19,15"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,25462074,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val778Glu/c.2333T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|T),22217,281,22690,"0,0123843103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,62",Deleterious,2,Damaging,"28,38","19,47"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,25462074,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val778Glu/c.2333T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|T),12475,139,12732,"0,0109173735",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,62",Deleterious,2,Damaging,"28,2","18,57"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,25462074,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val778Glu/c.2333T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|T),25380,262,25871,"0,0101271694",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,62",Deleterious,2,Damaging,"28,59","18,02"
"low bq, low freq, many artifacts, many samples",UPN2_056,2,25462074,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val778Glu/c.2333T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|T),7398,89,7565,"0,0117647059",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,62",Deleterious,2,Damaging,"28,36","17,94"
"low bq, low freq, many artifacts",UPN2_058,2,25462074,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val778Glu/c.2333T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|T),11611,136,11836,"0,0114903684",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,62",Deleterious,2,Damaging,"28,79","18,79"
"inspected, bad alignment, many artifacts",UPN2_093,2,25462074,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val778Glu/c.2333T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|T),4010,44,4086,"0,0107684777",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,62",Deleterious,"0,002",Damaging,"30,88","30,8"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_002,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),9321,95,9487,"0,010013703",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"24,86","15,08"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_003,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),1794,20,1823,"0,010970927",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"24,93","14,35"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_041,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),3590,44,3679,"0,0119597717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"25,47","15,61"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),26087,279,26610,"0,0104847802",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"25,48","14,5"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_005,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2943,33,3002,"0,0109926716",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"25,52","15,03"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),23920,266,24448,"0,0108802356",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"25,3","14,48"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),19344,218,19696,"0,0110682372",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"25,16","14,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),27100,299,27662,"0,0108090521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"25,47","14,9"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),16275,176,16599,"0,0106030484",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"25,3","14,44"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),17053,184,17441,"0,0105498538",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"24,96","14,84"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),22203,269,22705,"0,0118476107",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"25,07","14,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_007,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),20464,214,20830,"0,0102736438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"26,02","15,24"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_008,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),32107,386,32726,"0,0117949031",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"25,18","14,99"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_009,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),25483,286,25960,"0,0110169492",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"25,57","14,75"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_010,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),13733,171,14003,"0,0122116689",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"25,15","14,33"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_011,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),16260,205,16566,"0,0123747435",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"25,76","15,03"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),14059,157,14353,"0,0109384798",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"25,51","15,75"
"low bq, bad alignment, many samples",UPN2_059,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2107,76,2205,"0,0344671202",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"24,23","14,88"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_012,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),10597,111,10786,"0,0102911181",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"25,8","15,01"
"low bq, bad alignment, many samples",UPN2_060,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2871,92,2979,"0,0308828466",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"24,24","14,35"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_013,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),5325,58,5415,"0,010710988",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"25,67","14,78"
"low bq, bad alignment, many samples",UPN2_061,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),4228,138,4394,"0,0314064634",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"23,64","15,31"
"low bq, bad alignment, many samples",UPN2_062,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),3625,136,3790,"0,035883905",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"23,54","14,49"
"low bq, bad alignment, many samples",UPN2_063,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),3260,110,3392,"0,0324292453",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"24,14","14,66"
"low bq, bad alignment, many samples",UPN2_064,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2381,80,2474,"0,0323362975",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"24,14","15,23"
"low bq, bad alignment, many samples",UPN2_065,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2211,87,2318,"0,0375323555",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"23,73","15,24"
"low bq, bad alignment, many samples",UPN2_066,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),831,38,875,"0,0434285714",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"23,83",14
"low bq, bad alignment, many samples",UPN2_067,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),964,42,1015,"0,0413793103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"24,43","14,9"
"low bq, bad alignment, many samples",UPN2_068,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),1663,62,1741,"0,0356117174",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"23,38","15,26"
"low bq, bad alignment, many samples",UPN2_069,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2737,130,2886,"0,045045045",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"23,63","15,01"
"low bq, bad alignment, many samples",UPN2_070,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),1819,75,1915,"0,0391644909",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"23,84","15,09"
"low bq, bad alignment, many samples",UPN2_071,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),4560,148,4732,"0,0312764159",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"23,86","15,04"
"low bq, bad alignment, many samples",UPN2_072,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),4553,161,4748,"0,0339090143",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"24,03","14,81"
"low bq, bad alignment, many samples",UPN2_073,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2752,77,2846,"0,0270555165",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"24,15","14,79"
"low bq, bad alignment, many samples",UPN2_074,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),1223,39,1266,"0,0308056872",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"23,68","14,51"
"low bq, bad alignment, many samples",UPN2_075,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),4239,144,4415,"0,0326160815",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"24,17","14,51"
"low bq, bad alignment, many samples",UPN2_076,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2427,100,2545,"0,0392927308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"23,43","14,91"
"low bq, bad alignment, many samples",UPN2_077,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2518,90,2619,"0,0343642612",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"22,85","15,17"
"low bq, bad alignment, many samples",UPN2_078,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),3082,115,3223,"0,0356810425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"23,06","14,56"
"low bq, bad alignment, many samples",UPN2_079,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2201,54,2260,"0,0238938053",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"23,69","15,22"
"low bq, bad alignment, many samples",UPN2_080,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),4010,141,4181,"0,0337239895",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"23,57","15,75"
"low bq, bad alignment, many samples",UPN2_081,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),6476,250,6776,"0,0368949233",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"24,11","14,88"
"low bq, bad alignment, many samples",UPN2_082,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2190,67,2272,"0,0294894366",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"23,99","14,4"
"low bq, bad alignment, many samples",UPN2_083,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),3769,128,3916,"0,0326864147",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"23,65","14,71"
"low bq, bad alignment, many samples",UPN2_084,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2956,121,3091,"0,0391459075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"23,42","14,87"
"low bq, bad alignment, many samples",UPN2_085,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),1823,71,1917,"0,037037037",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"24,19","15,45"
"low bq, bad alignment, many samples",UPN2_086,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),824,25,857,"0,0291715286",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"23,69","14,56"
"low bq, bad alignment, many samples",UPN2_087,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2310,69,2396,"0,0287979967",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"23,96","14,93"
"low bq, bad alignment",UPN2_088,2,25462080,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn776Thr/c.2327A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),1957,68,2031,"0,0334810438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,19,Damaging,"24,5","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,25462081,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn776His/c.2326A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2165,34,2205,"0,0154195011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,5",Deleterious,38,Damaging,"28,04","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25462081,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn776His/c.2326A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2927,38,2978,"0,0127602418",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,5",Deleterious,38,Damaging,"28,17","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25462081,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn776His/c.2326A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),4316,51,4394,"0,0116067365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,5",Deleterious,38,Damaging,"27,86",15
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25462081,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn776His/c.2326A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),3728,50,3789,"0,013196094",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,5",Deleterious,38,Damaging,"27,49","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25462081,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn776His/c.2326A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),3341,35,3390,"0,0103244838",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,5",Deleterious,38,Damaging,"28,27","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,25462081,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn776His/c.2326A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2284,29,2317,"0,0125161847",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,5",Deleterious,38,Damaging,"28,07",14
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25462081,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn776His/c.2326A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),1718,22,1740,"0,0126436782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,5",Deleterious,38,Damaging,"27,52","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25462081,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn776His/c.2326A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2823,40,2885,"0,013864818",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,5",Deleterious,38,Damaging,"27,68","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,25462081,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn776His/c.2326A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),1870,28,1914,"0,0146290491",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,5",Deleterious,38,Damaging,"27,27","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25462081,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn776His/c.2326A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),4639,72,4729,"0,0152252062",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,5",Deleterious,38,Damaging,"28,06","15,6"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25462081,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn776His/c.2326A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),4635,71,4746,"0,0149599663",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,5",Deleterious,38,Damaging,"27,91","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25462081,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn776His/c.2326A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2804,32,2845,"0,0112478032",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,5",Deleterious,38,Damaging,"27,82","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25462081,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn776His/c.2326A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),4346,46,4413,"0,010423748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,5",Deleterious,38,Damaging,"28,08","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25462081,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn776His/c.2326A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2493,32,2542,"0,012588513",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,5",Deleterious,38,Damaging,"27,38","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25462081,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn776His/c.2326A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2574,28,2619,"0,0106911035",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,5",Deleterious,38,Damaging,"27,43",14
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25462081,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn776His/c.2326A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),3154,54,3221,"0,0167649798",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,5",Deleterious,38,Damaging,"27,56","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25462081,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn776His/c.2326A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2226,24,2259,"0,01062417",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,5",Deleterious,38,Damaging,"27,61","16,88"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25462081,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn776His/c.2326A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),4103,48,4179,"0,0114860014",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,5",Deleterious,38,Damaging,"27,73","15,42"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25462081,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn776His/c.2326A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),6630,93,6775,"0,0137269373",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,5",Deleterious,38,Damaging,"28,06","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25462081,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn776His/c.2326A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2230,30,2271,"0,0132100396",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,5",Deleterious,38,Damaging,"27,68","15,63"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25462081,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn776His/c.2326A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),3861,40,3915,"0,0102171137",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,5",Deleterious,38,Damaging,"27,82","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25462081,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn776His/c.2326A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),3022,49,3090,"0,0158576052",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,5",Deleterious,38,Damaging,"27,7","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,25462081,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn776His/c.2326A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),1874,30,1915,"0,0156657963",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,5",Deleterious,38,Damaging,"27,86","15,63"
"low bq, low freq, many artifacts, many samples",UPN2_087,2,25462081,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn776His/c.2326A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),2362,24,2396,"0,0100166945",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,5",Deleterious,38,Damaging,"27,78",14
"low bq, low freq, many artifacts",UPN2_088,2,25462081,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn776His/c.2326A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|20|G),1997,26,2031,"0,0128015756",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,5",Deleterious,38,Damaging,"28,48",14
"inspected, bad alignment, many artifacts",UPN2_044,2,25463178,A,G,missense_variant(MODERATE|MISSENSE|tTt/tCt|p.Phe772Ser/c.2315T>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|G),3495,42,3540,"0,0118644068",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,86",Deleterious,"0,003",Damaging,"35,23","34,76"
inspected,UPN2_053,2,25463182,G,A,stop_gained(HIGH|NONSENSE|Cga/Tga|p.Arg771*/c.2311C>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),16876,208,17117,"0,0121516621",0,0,0,0,1,0,0,1,2,NO,NO,COSM231563,haematopoietic_and_lymphoid_tissue,5,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,09","35,41"
"inspected, bad alignment, many artifacts",UPN2_044,2,25463196,T,C,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys766Arg/c.2297A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),3476,55,3540,"0,0155367232",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,48",Neutral,"0,336",Tolerated,"35,08","34,53"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25463205,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val763Gly/c.2288T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),9936,106,10097,"0,0104981678",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,59",Deleterious,"0,06",Tolerated,"29,71",15
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25463205,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val763Gly/c.2288T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),10320,118,10466,"0,0112746035",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,59",Deleterious,"0,06",Tolerated,"29,61","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25463205,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val763Gly/c.2288T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),5282,57,5362,"0,0106303618",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,59",Deleterious,"0,06",Tolerated,"29,77","15,61"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25463205,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val763Gly/c.2288T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),8832,103,8976,"0,0114750446",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,59",Deleterious,"0,06",Tolerated,"29,64","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,25463205,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val763Gly/c.2288T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),5288,60,5377,"0,0111586386",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,59",Deleterious,"0,06",Tolerated,"29,73","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25463205,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val763Gly/c.2288T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),7882,81,7987,"0,0101414799",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,59",Deleterious,"0,06",Tolerated,"30,11","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25463205,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val763Gly/c.2288T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),7986,81,8095,"0,0100061767",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,59",Deleterious,"0,06",Tolerated,"29,8","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25463205,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val763Gly/c.2288T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),9101,106,9248,"0,0114619377",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,59",Deleterious,"0,06",Tolerated,"29,72","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25463205,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val763Gly/c.2288T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),6292,69,6391,"0,0107964325",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,59",Deleterious,"0,06",Tolerated,"29,98","16,25"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25463205,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val763Gly/c.2288T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),9351,101,9490,"0,0106427819",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,59",Deleterious,"0,06",Tolerated,"29,55","15,91"
"low bq, low freq, many artifacts",UPN2_086,2,25463205,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val763Gly/c.2288T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),2974,43,3034,"0,0141727093",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,59",Deleterious,"0,06",Tolerated,"29,51","14,49"
"inspected, bad alignment, many artifacts",UPN2_044,2,25463214,GC,G,frameshift_variant(HIGH||gcc/|p.Ala760fs/c.2278delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|G),3429,36,3539,"0,0101723651",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,35,NA
"low freq, many artifacts",UPN2_044,2,25463215,C,T,missense_variant(MODERATE|MISSENSE|Gcc/Acc|p.Ala760Thr/c.2278G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|T),3429,55,3539,"0,0155411133",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,19",Deleterious,15,Damaging,35,"34,29"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,25463217,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val759Gly/c.2276T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),5025,70,5120,"0,013671875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,75",Deleterious,17,Damaging,"27,98","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25463217,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val759Gly/c.2276T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),8590,135,8761,"0,0154091999",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,75",Deleterious,17,Damaging,"27,9","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25463217,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val759Gly/c.2276T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),9877,170,10097,"0,0168366842",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,75",Deleterious,17,Damaging,"27,6","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25463217,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val759Gly/c.2276T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),10203,212,10462,"0,0202638119",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,75",Deleterious,17,Damaging,"27,27","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25463217,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val759Gly/c.2276T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),8530,127,8699,"0,0145993792",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,75",Deleterious,17,Damaging,"27,8","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25463217,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val759Gly/c.2276T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),7656,116,7802,"0,0148679826",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,75",Deleterious,17,Damaging,"27,85","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,25463217,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val759Gly/c.2276T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),3968,78,4057,"0,0192260291",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,75",Deleterious,17,Damaging,"28,17","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_066,2,25463217,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val759Gly/c.2276T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),2740,48,2799,"0,0171489818",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,75",Deleterious,17,Damaging,"28,06","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_067,2,25463217,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val759Gly/c.2276T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),3628,64,3708,"0,0172599784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,75",Deleterious,17,Damaging,"28,47","14,11"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25463217,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val759Gly/c.2276T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),5247,94,5361,"0,0175340422",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,75",Deleterious,17,Damaging,"27,42","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25463217,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val759Gly/c.2276T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),8777,163,8974,"0,0181635837",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,75",Deleterious,17,Damaging,"27,63","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,25463217,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val759Gly/c.2276T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),5240,101,5373,"0,0187976922",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,75",Deleterious,17,Damaging,"27,14","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25463217,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val759Gly/c.2276T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),9787,160,9980,"0,0160320641",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,75",Deleterious,17,Damaging,"27,91","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25463217,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val759Gly/c.2276T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),11124,197,11359,"0,017343076",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,75",Deleterious,17,Damaging,"27,65","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25463217,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val759Gly/c.2276T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),7829,124,7982,"0,0155349536",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,75",Deleterious,17,Damaging,"27,85","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,25463217,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val759Gly/c.2276T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),4019,52,4088,"0,0127201566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,75",Deleterious,17,Damaging,"28,11","14,13"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25463217,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val759Gly/c.2276T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),12114,152,12334,"0,0123236582",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,75",Deleterious,17,Damaging,"28,35",15
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25463217,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val759Gly/c.2276T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),7893,146,8093,"0,0180402817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,75",Deleterious,17,Damaging,"27,49","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25463217,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val759Gly/c.2276T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),7250,124,7425,"0,0167003367",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,75",Deleterious,17,Damaging,"27,57","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25463217,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val759Gly/c.2276T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),9055,147,9244,"0,0159022068",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,75",Deleterious,17,Damaging,"27,43","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25463217,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val759Gly/c.2276T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),6244,118,6387,"0,0184750274",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,75",Deleterious,17,Damaging,"27,85","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25463217,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val759Gly/c.2276T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),11429,185,11678,"0,0158417537",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,75",Deleterious,17,Damaging,"27,63","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25463217,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val759Gly/c.2276T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),14086,234,14378,"0,0162748644",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,75",Deleterious,17,Damaging,"27,97","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25463217,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val759Gly/c.2276T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),5728,82,5841,"0,014038692",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,75",Deleterious,17,Damaging,"28,05","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25463217,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val759Gly/c.2276T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),9270,172,9489,"0,0181262514",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,75",Deleterious,17,Damaging,"27,54","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25463217,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val759Gly/c.2276T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),8556,181,8790,"0,0205915813",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,75",Deleterious,17,Damaging,"27,26","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,25463217,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val759Gly/c.2276T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),4616,82,4709,"0,0174134636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,75",Deleterious,17,Damaging,"27,81","15,5"
"low bq, low freq, many artifacts, many samples",UPN2_086,2,25463217,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val759Gly/c.2276T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),2950,58,3032,"0,0191292876",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,75",Deleterious,17,Damaging,"27,17","15,34"
"low bq, low freq, many artifacts, many samples",UPN2_087,2,25463217,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val759Gly/c.2276T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),8900,164,9098,"0,0180259398",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,75",Deleterious,17,Damaging,"27,73","14,55"
"low bq, low freq, many artifacts",UPN2_088,2,25463217,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val759Gly/c.2276T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),5516,79,5617,"0,0140644472",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,75",Deleterious,17,Damaging,"28,19","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_001,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),14487,237,14789,"0,0160254243",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"28,74",16
"low bq, low freq, many artifacts, many samples",UPN2_014,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),21561,237,21886,"0,0108288404",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"28,83","16,32"
"low bq, low freq, many artifacts, many samples",UPN2_015,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),28873,443,29437,"0,0150490879",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"28,27","16,47"
"low bq, low freq, many artifacts, many samples",UPN2_017,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),9638,113,9783,"0,0115506491",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"28,57","16,4"
"low bq, low freq, many artifacts, many samples",UPN2_018,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),15408,204,15685,"0,0130060567",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"28,6","15,71"
"low bq, low freq, many artifacts, many samples",UPN2_019,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),16484,224,16795,"0,0133373028",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"28,41","16,69"
"low bq, low freq, many artifacts, many samples",UPN2_020,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),14446,154,14659,"0,0105054915",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"28,92","15,5"
"low bq, low freq, many artifacts, many samples",UPN2_002,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),18695,339,19108,"0,0177412602",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"28,19","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_003,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),3653,58,3727,"0,0155621143",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"28,43","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_022,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),21421,251,21756,"0,0115370473",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"28,54","15,58"
"low bq, low freq, many artifacts, many samples",UPN2_023,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),25447,296,25850,"0,011450677",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"28,53","16,07"
"low bq, low freq, many artifacts, many samples",UPN2_041,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),26498,291,26916,"0,0108114133",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"29,84","16,47"
"low bq, low freq, many artifacts, many samples",UPN2_024,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),11310,166,11517,"0,0144134757",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"28,76","16,48"
"low bq, low freq, many artifacts, many samples",UPN2_025,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),28418,332,28870,"0,0114998268",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"28,72","15,92"
"low bq, low freq, many artifacts, many samples",UPN2_026,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),27400,373,27855,"0,0133907736",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"28,29","15,52"
"low bq, low freq, many artifacts, many samples",UPN2_004,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),2062,36,2108,"0,0170777989",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"28,13","15,58"
"low bq, low freq, many artifacts, many samples",UPN2_027,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),28415,384,28928,"0,0132743363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"28,33","15,54"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),38405,523,39118,"0,0133698042",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"29,79","17,28"
"low bq, low freq, many artifacts, many samples",UPN2_028,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),21187,349,21625,"0,0161387283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"28,12","16,66"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),24857,266,25224,"0,0105455122",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"29,94","16,93"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),6794,79,6923,"0,0114112379",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"29,82","16,56"
"low bq, low freq, many artifacts, many samples",UPN2_029,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),27304,324,27763,"0,0116702086",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"28,66","16,73"
"low bq, low freq, many artifacts, many samples",UPN2_030,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),22931,266,23318,"0,0114074964",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"28,5","16,59"
"low bq, low freq, many artifacts, many samples",UPN2_031,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),16301,213,16577,"0,0128491283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"28,74","16,29"
"low bq, low freq, many artifacts, many samples",UPN2_005,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),6745,112,6892,"0,0162507255",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"28,48","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),32855,400,33413,"0,0119713884",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"29,67","17,05"
"low bq, low freq, many artifacts, many samples",UPN2_032,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),9207,116,9374,"0,0123746533",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"28,7","17,6"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),33672,432,34263,"0,012608353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"29,64","16,33"
"low bq, low freq, many artifacts, many samples",UPN2_033,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),17839,204,18100,"0,0112707182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"28,88","16,72"
"low bq, low freq, many artifacts, many samples",UPN2_034,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),6660,88,6780,"0,012979351",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"28,39","17,27"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),47173,602,48026,"0,0125348769",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"29,84","17,28"
"low bq, low freq, many artifacts, many samples",UPN2_048,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),35319,389,35836,"0,0108550061",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"29,91","15,82"
"low bq, low freq, many artifacts, many samples",UPN2_035,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),24264,304,24659,"0,012328156",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"28,6","15,57"
"low bq, low freq, many artifacts, many samples",UPN2_036,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),37431,472,38042,"0,0124073393",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"28,54","16,09"
"low bq, low freq, many artifacts, many samples",UPN2_006,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),9853,161,10047,"0,016024684",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"28,34","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),33875,432,34457,"0,0125373654",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"29,76","17,07"
"low bq, low freq, many artifacts, many samples",UPN2_037,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),40450,571,41219,"0,0138528349",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"28,31","16,2"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),26549,272,26950,"0,0100927644",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"29,99","17,36"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),28179,359,28697,"0,0125100185",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"29,62","16,92"
"low bq, low freq, many artifacts, many samples",UPN2_038,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),39725,539,40431,"0,0133313547",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"28,4","15,96"
"low bq, low freq, many artifacts, many samples",UPN2_039,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),31130,471,31747,"0,0148360475",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"28,26","15,25"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),32935,397,33509,"0,0118475633",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"29,64","16,47"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),23817,355,24294,"0,0146126616",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"29,55","17,06"
"low bq, low freq, many artifacts, many samples",UPN2_007,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),42611,603,43434,"0,013883133",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"28,81","15,45"
"low bq, low freq, many artifacts, many samples",UPN2_008,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),59873,953,61091,"0,0155996792",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"28,56","15,17"
"low bq, low freq, many artifacts, many samples",UPN2_009,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),48157,790,49124,"0,0160817523",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"28,6","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_010,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),33370,590,34110,"0,0172969804",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"28,45","15,39"
"low bq, low freq, many artifacts, many samples",UPN2_011,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),38928,568,39676,"0,0143159593",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"28,94","15,92"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),36335,410,36916,"0,0111062954",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"29,74","17,3"
"low bq, low freq, many artifacts, many samples",UPN2_056,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),18906,240,19251,"0,0124668848",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"29,74","16,54"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),35742,408,36321,"0,0112331709",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"29,7","16,68"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),35077,384,35605,"0,0107850021",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"29,9","16,17"
"low bq, low freq, many artifacts, many samples",UPN2_012,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),20843,334,21280,"0,0156954887",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"28,78","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_040,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),12474,183,12726,"0,0143800094",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"28,62","16,9"
"low bq, low freq, many artifacts",UPN2_013,2,25463226,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu756Val/c.2267A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),12654,230,12943,"0,0177702233",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,66,Tolerated,"28,78","15,68"
"inspected, low freq, no database",UPN2_075,2,25463242,AG,A,frameshift_variant(HIGH||ccc/|p.Phe751fs/c.2250delC|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),24015,337,24435,"0,0137916922",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,98",NA
inspected,UPN2_111,2,25463248,G,A,missense_variant(MODERATE|MISSENSE|Cgc/Tgc|p.Arg749Cys/c.2245C>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|A),20554,418,21012,"0,0198933943",0,0,0,0,1,1,0,1,3,NO,NO,COSM219133,"haematopoietic_and_lymphoid_tissue, skin","4, 1",NO,NO,NO,NA,NO,NO,"-7,73",Deleterious,"0,023",Damaging,"33,57","34,13"
"low bq, low freq, many artifacts",UPN2_054,2,25463273,A,T,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp740Glu/c.2220T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|T),24092,295,24527,"0,0120275615",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,51",Neutral,337,Tolerated,"32,91","19,39"
"inspected, bad alignment, many artifacts",UPN2_041,2,25463276,A,T,missense_variant(MODERATE|MISSENSE|caT/caA|p.His739Gln/c.2217T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|T),26817,303,27224,"0,0111298854",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,43",Neutral,"0,281",Tolerated,"33,19","25,46"
,UPN2_106,2,25463289,T,C,missense_variant(MODERATE|MISSENSE|tAc/tGc|p.Tyr735Cys/c.2204A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),22557,336,22932,"0,0146520147",0,0,0,0,1,1,0,1,3,"0,0116",NO,COSM133126,haematopoietic_and_lymphoid_tissue,5,NO,rs147828672,NO,NA,NO,NO,"-8,27",Deleterious,"0,095",Tolerated,"32,71","31,77"
"low bq, low freq, many artifacts",UPN2_049,2,25463293,A,T,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe734Ile/c.2200T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|T),17099,177,17350,"0,0102017291",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,62",Deleterious,6,Damaging,"33,74","16,05"
"low bq, low freq, many artifacts, many samples",UPN2_041,2,25463297,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe732Leu/c.2196T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|T),13294,137,13499,"0,0101488999",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,"0,02",Damaging,"33,92","20,91"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,25463297,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe732Leu/c.2196T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|T),16891,196,17175,"0,011411936",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,"0,02",Damaging,"34,08","22,26"
"low bq, low freq, many artifacts, many samples",UPN2_056,2,25463297,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe732Leu/c.2196T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|T),9484,105,9654,"0,0108763207",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,"0,02",Damaging,"34,02","18,92"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,25463297,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe732Leu/c.2196T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|T),17953,212,18244,"0,0116202587",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,"0,02",Damaging,"33,99","21,17"
"low bq, low freq, many artifacts",UPN2_058,2,25463297,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe732Leu/c.2196T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|T),17595,200,17897,"0,0111750573",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,"0,02",Damaging,"34,05","21,3"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,25463298,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe732Tyr/c.2195T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|T),12396,139,12620,"0,0110142631",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,95",Deleterious,77,Tolerated,"33,6","17,43"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,25463298,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe732Tyr/c.2195T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|T),17044,177,17324,"0,0102170399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,95",Deleterious,77,Tolerated,"33,4","16,55"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,25463298,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe732Tyr/c.2195T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|T),16683,174,16951,"0,0102648811",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,95",Deleterious,77,Tolerated,"33,43","17,44"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,25463298,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe732Tyr/c.2195T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|T),14195,145,14411,"0,0100617584",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,95",Deleterious,77,Tolerated,"33,47","18,15"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,25463298,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe732Tyr/c.2195T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|T),16543,187,16793,"0,0111355922",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,95",Deleterious,77,Tolerated,"33,38","16,79"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,25463298,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe732Tyr/c.2195T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|T),18219,195,18520,"0,0105291577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,95",Deleterious,77,Tolerated,"33,48","16,21"
"low bq, low freq, many artifacts",UPN2_057,2,25463298,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe732Tyr/c.2195T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|T),17952,205,18244,"0,0112365709",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,95",Deleterious,77,Tolerated,"33,5","18,9"
"inspected, low freq",UPN2_101,2,25463307,CG,C,frameshift_variant(HIGH||cgg/|p.Arg729fs/c.2185delC|912|DNMT3A|protein_coding|CODING|ENST00000264709|19|C),8272,101,8406,"0,0120152272",0,0,0,1,1,0,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,91",NA
inspected,UPN2_111,2,25463508,C,T,splice_donor_variant+intron_variant(HIGH|||c.2173+1G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|18|T),7962,155,8131,"0,0190628459",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"2,47E-005",NO,NO,,,,,"34,3","34,24"
"Not in 2nd Illumina, bad alignment, many artifacts",UPN2_006,2,25463527,C,T,missense_variant(MODERATE|MISSENSE|Gct/Act|p.Ala719Thr/c.2155G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|18|T),4079,44,4124,"0,0106692532",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,24",Deleterious,"0,033",Damaging,"33,82","34,95"
"Not in 2nd Illumina, bad alignment, many artifacts",UPN2_006,2,25463553,C,T,missense_variant(MODERATE|MISSENSE|tGc/tAc|p.Cys710Tyr/c.2129G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|18|T),4071,47,4125,"0,0113939394",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-10,8",Deleterious,0,Damaging,"35,47","34,81"
"low freq, many artifacts",UPN2_044,2,25463560,T,TG,frameshift_variant(HIGH||ggc/ggcC|p.Ser708fs/c.2121dupC|912|DNMT3A|protein_coding|CODING|ENST00000264709|18|TG),2919,44,2930,"0,0150170648",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,4",NA
"low freq, many artifacts",UPN2_044,2,25463561,G,GC,frameshift_variant(HIGH||ggc/ggGc|p.Ser708fs/c.2120dupG|912|DNMT3A|protein_coding|CODING|ENST00000264709|18|GC),2925,51,2930,"0,0174061433",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,47",NA
"Not in 2nd Illumina, bad alignment, many artifacts",UPN2_006,2,25463578,C,T,missense_variant(MODERATE|MISSENSE|Gat/Aat|p.Asp702Asn/c.2104G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|18|T),1510,31,1542,"0,0201037613",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-4,91",Deleterious,"0,013",Damaging,"35,46","32,39"
"inspected, bad alignment, many artifacts",UPN2_080,2,25463583,G,A,missense_variant(MODERATE|MISSENSE|cCa/cTa|p.Pro700Leu/c.2099C>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|18|A),10052,145,10228,"0,0141767697",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,82",Deleterious,0,Damaging,"34,66","35,53"
"inspected, bad alignment, many artifacts",UPN2_042,2,25463590,A,G,missense_variant(MODERATE|MISSENSE|Tgg/Cgg|p.Trp698Arg/c.2092T>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|18|G),7272,103,7424,"0,0138739224",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-13,28",Deleterious,"0,003",Damaging,"31,01","34,5"
"Not in 2nd Illumina, bad alignment, many artifacts",UPN2_006,2,25463590,A,G,missense_variant(MODERATE|MISSENSE|Tgg/Cgg|p.Trp698Arg/c.2092T>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|18|G),1457,41,1513,"0,0270984798",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-13,28",Deleterious,"0,003",Damaging,"30,36","35,61"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25464444,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val690Gly/c.2069T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),8980,92,9110,"0,0100987925",0,0,0,0,1,0,0,0,1,NO,NO,COSM1583090,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,"29,23","18,92"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25464444,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val690Gly/c.2069T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),8885,94,9023,"0,0104178211",0,0,0,0,1,0,0,0,1,NO,NO,COSM1583090,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,"28,73","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25464444,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val690Gly/c.2069T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),8277,85,8404,"0,0101142313",0,0,0,0,1,0,0,0,1,NO,NO,COSM1583090,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,29,"15,68"
"low bq, bad alignment, many samples",UPN2_059,2,25464462,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val684Gly/c.2051T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),15176,467,15690,"0,029764181",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,"25,38","15,5"
"low bq, bad alignment, many samples",UPN2_060,2,25464462,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val684Gly/c.2051T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),8740,247,9020,"0,027383592",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,"25,5","15,56"
"low bq, low freq, many artifacts, many samples",UPN2_092,2,25464462,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val684Gly/c.2051T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),2316,25,2349,"0,0106428267",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,"28,07","15,76"
"low bq, bad alignment, many samples",UPN2_061,2,25464462,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val684Gly/c.2051T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),8805,274,9108,"0,0300834431",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,"25,16","15,29"
"low bq, bad alignment, many samples",UPN2_062,2,25464462,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val684Gly/c.2051T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),7838,247,8125,"0,0304",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,"24,75","15,37"
"low bq, bad alignment, many samples",UPN2_063,2,25464462,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val684Gly/c.2051T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),8631,259,8913,"0,0290586783",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,"25,16","15,23"
"low bq, bad alignment, many samples",UPN2_064,2,25464462,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val684Gly/c.2051T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),13428,418,13891,"0,0300914261",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,"25,19","15,44"
"low bq, bad alignment, many samples",UPN2_065,2,25464462,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val684Gly/c.2051T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),11383,373,11811,"0,0315807298",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,"25,35","15,39"
"low bq, bad alignment, many samples",UPN2_066,2,25464462,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val684Gly/c.2051T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),12471,377,12914,"0,0291931237",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,"25,51","15,25"
"low bq, bad alignment, many samples",UPN2_067,2,25464462,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val684Gly/c.2051T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),11666,318,12032,"0,0264295213",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,"25,98","15,03"
"low bq, bad alignment, many samples",UPN2_068,2,25464462,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val684Gly/c.2051T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),8666,326,9021,"0,0361379005",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,"24,78","15,12"
"low bq, bad alignment, many samples",UPN2_069,2,25464462,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val684Gly/c.2051T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),10474,364,10880,"0,0334558824",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,"25,03","15,62"
"low bq, bad alignment, many samples",UPN2_070,2,25464462,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val684Gly/c.2051T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),6371,201,6591,"0,0304961311",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,"24,7","15,84"
"low bq, bad alignment, many samples",UPN2_071,2,25464462,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val684Gly/c.2051T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),5535,191,5747,"0,0332347312",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,"25,32","15,23"
"low bq, bad alignment, many samples",UPN2_072,2,25464462,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val684Gly/c.2051T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),7721,228,7990,"0,0285356696",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,"25,36","15,04"
"low bq, bad alignment, many samples",UPN2_073,2,25464462,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val684Gly/c.2051T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),7614,238,7867,"0,0302529554",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,"25,42","15,2"
"low bq, bad alignment, many samples",UPN2_074,2,25464462,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val684Gly/c.2051T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),6251,198,6474,"0,030583874",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,"25,49","14,91"
"low bq, bad alignment, many samples",UPN2_075,2,25464462,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val684Gly/c.2051T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),10007,267,10308,"0,0259022119",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,"25,87","15,16"
"low bq, bad alignment, many samples",UPN2_076,2,25464462,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val684Gly/c.2051T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),8055,315,8399,"0,0375044648",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,"24,6","15,5"
"low bq, bad alignment, many samples",UPN2_077,2,25464462,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val684Gly/c.2051T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),10583,330,10941,"0,0301617768",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,"25,06","15,11"
"low bq, bad alignment, many samples",UPN2_078,2,25464462,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val684Gly/c.2051T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),8692,315,9033,"0,0348721355",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,"24,85","15,28"
"low bq, bad alignment, many samples",UPN2_079,2,25464462,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val684Gly/c.2051T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),5852,193,6086,"0,0317121262",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,"25,29","14,95"
"low bq, bad alignment, many samples",UPN2_080,2,25464462,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val684Gly/c.2051T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),8627,293,8960,"0,0327008929",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,"25,31","15,46"
"low bq, bad alignment, many samples",UPN2_081,2,25464462,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val684Gly/c.2051T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),14588,509,15153,"0,0335907081",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,"25,35","15,19"
"low bq, bad alignment, many samples",UPN2_082,2,25464462,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val684Gly/c.2051T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),11653,369,12064,"0,03058687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,"25,87","15,27"
"low bq, bad alignment, many samples",UPN2_083,2,25464462,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val684Gly/c.2051T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),10008,406,10458,"0,0388219545",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,"24,69","15,34"
"low bq, bad alignment, many samples",UPN2_084,2,25464462,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val684Gly/c.2051T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),10481,395,10923,"0,0361622265",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,"24,91","15,07"
"low bq, bad alignment, many samples",UPN2_085,2,25464462,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val684Gly/c.2051T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),8737,280,9062,"0,0308982565",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,"25,19","15,3"
"low bq, bad alignment, many samples",UPN2_086,2,25464462,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val684Gly/c.2051T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),6074,207,6296,"0,0328780178",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,"24,79","14,9"
"low bq, bad alignment, many samples",UPN2_087,2,25464462,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val684Gly/c.2051T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),12358,348,12756,"0,0272812794",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,"25,22","15,25"
"low bq, bad alignment",UPN2_088,2,25464462,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val684Gly/c.2051T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),9523,265,9831,"0,0269555488",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,"25,96","15,14"
"inspected, bad alignment, many artifacts",UPN2_044,2,25464462,A,G,missense_variant(MODERATE|MISSENSE|gTc/gCc|p.Val684Ala/c.2051T>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),2315,25,2362,"0,0105842506",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,0,Damaging,"25,63","34,64"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,25464471,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile681Ser/c.2042T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),15431,209,15690,"0,0133205864",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,77",Deleterious,4,Damaging,"29,28","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25464471,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile681Ser/c.2042T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),8948,118,9109,"0,0129542211",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,77",Deleterious,4,Damaging,"29,06","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25464471,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile681Ser/c.2042T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),8005,99,8125,"0,0121846154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,77",Deleterious,4,Damaging,"28,82","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25464471,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile681Ser/c.2042T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),8759,120,8913,"0,0134634803",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,77",Deleterious,4,Damaging,"29,29","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25464471,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile681Ser/c.2042T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),13695,169,13890,"0,0121670266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,77",Deleterious,4,Damaging,"29,18","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,25464471,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile681Ser/c.2042T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),11634,136,11810,"0,0115156647",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,77",Deleterious,4,Damaging,"29,47","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_066,2,25464471,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile681Ser/c.2042T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),12728,132,12914,"0,0102214651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,77",Deleterious,4,Damaging,"29,47","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25464471,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile681Ser/c.2042T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),8876,111,9022,"0,0123032587",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,77",Deleterious,4,Damaging,"28,66","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25464471,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile681Ser/c.2042T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),10712,133,10877,"0,0122276363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,77",Deleterious,4,Damaging,"28,98","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,25464471,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile681Ser/c.2042T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),6481,76,6591,"0,0115308754",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,77",Deleterious,4,Damaging,"28,57","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25464471,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile681Ser/c.2042T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),5671,60,5747,"0,0104402297",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,77",Deleterious,4,Damaging,"29,05","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25464471,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile681Ser/c.2042T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),7872,89,7990,"0,0111389237",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,77",Deleterious,4,Damaging,"29,07","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25464471,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile681Ser/c.2042T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),7746,103,7868,"0,0130910015",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,77",Deleterious,4,Damaging,"29,25","15,34"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,25464471,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile681Ser/c.2042T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),6384,67,6474,"0,0103490887",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,77",Deleterious,4,Damaging,"29,38","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25464471,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile681Ser/c.2042T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),10161,116,10308,"0,0112533954",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,77",Deleterious,4,Damaging,"29,97","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25464471,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile681Ser/c.2042T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),8231,140,8399,"0,016668651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,77",Deleterious,4,Damaging,"28,92","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25464471,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile681Ser/c.2042T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),10775,133,10941,"0,01215611",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,77",Deleterious,4,Damaging,"29,16","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25464471,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile681Ser/c.2042T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),8871,118,9034,"0,0130617667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,77",Deleterious,4,Damaging,"28,92","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25464471,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile681Ser/c.2042T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),5985,68,6086,"0,0111731844",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,77",Deleterious,4,Damaging,"29,24","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25464471,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile681Ser/c.2042T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),8821,106,8961,"0,0118290369",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,77",Deleterious,4,Damaging,"29,31","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25464471,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile681Ser/c.2042T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),14921,177,15153,"0,0116808553",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,77",Deleterious,4,Damaging,"29,36","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25464471,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile681Ser/c.2042T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),11892,123,12063,"0,0101964685",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,77",Deleterious,4,Damaging,"29,6","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25464471,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile681Ser/c.2042T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),10267,154,10460,"0,0147227533",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,77",Deleterious,4,Damaging,"28,68","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25464471,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile681Ser/c.2042T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),10709,157,10923,"0,0143733407",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,77",Deleterious,4,Damaging,"28,76","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,25464471,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile681Ser/c.2042T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),8933,106,9062,"0,0116971971",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,77",Deleterious,4,Damaging,"28,99","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_086,2,25464471,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile681Ser/c.2042T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),6185,88,6296,"0,0139771283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,77",Deleterious,4,Damaging,"28,9","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_087,2,25464471,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile681Ser/c.2042T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),12570,144,12756,"0,0112888053",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,77",Deleterious,4,Damaging,"29,2","14,91"
"low bq, low freq, many artifacts",UPN2_088,2,25464471,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile681Ser/c.2042T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),9679,120,9831,"0,0122062862",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,77",Deleterious,4,Damaging,"29,99","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_014,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),6739,110,6875,"0,016",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,55","16,53"
"low bq, low freq, many artifacts, many samples",UPN2_015,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),8937,124,9106,"0,0136173951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,49","16,41"
"low bq, low freq, many artifacts, many samples",UPN2_016,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),4189,68,4275,"0,0159064327",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,51","16,54"
"low bq, low freq, many artifacts, many samples",UPN2_017,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),2885,64,2976,"0,0215053763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,55","15,45"
"low bq, low freq, many artifacts, many samples",UPN2_018,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),4629,77,4727,"0,0162894013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,55","16,39"
"low bq, low freq, many artifacts, many samples",UPN2_019,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),5103,99,5231,"0,0189256356",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,56","16,26"
"low bq, low freq, many artifacts, many samples",UPN2_020,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),4051,62,4129,"0,0150157423",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,66","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_021,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),5154,103,5289,"0,0194743808",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,34","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_002,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),4464,68,4553,"0,0149352076",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,12","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_022,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),6056,94,6195,"0,015173527",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,47","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_023,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),7194,126,7358,"0,0171242185",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,54","15,65"
"low bq, low freq, many artifacts, many samples",UPN2_041,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),16894,229,17265,"0,0132638286",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,41","16,21"
"low bq, low freq, many artifacts, many samples",UPN2_024,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),2972,53,3045,"0,0174055829",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,54","15,89"
"low bq, low freq, many artifacts, many samples",UPN2_025,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),8630,136,8816,"0,0154264973",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,57","15,97"
"low bq, low freq, many artifacts, many samples",UPN2_026,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),7570,134,7759,"0,0172702668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,58","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_027,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),8484,133,8666,"0,0153473344",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,47","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_089,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),4801,52,4880,"0,0106557377",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,95","18,5"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),10278,129,10475,"0,0123150358",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,36","16,03"
"low bq, low freq, many artifacts, many samples",UPN2_028,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),6034,99,6178,"0,0160246034",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,57","15,83"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),5961,67,6078,"0,0110233629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,44","16,55"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),2409,26,2451,"0,0106079151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,62","16,69"
"low bq, low freq, many artifacts, many samples",UPN2_029,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),6816,128,7001,"0,0182831024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,46","15,6"
"low bq, low freq, many artifacts, many samples",UPN2_030,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),7749,123,7923,"0,0155244226",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,47","16,28"
"low bq, low freq, many artifacts, many samples",UPN2_031,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),4797,65,4889,"0,0132951524",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,48","16,31"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),8694,107,8857,"0,01208084",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,4","16,89"
"low bq, low freq, many artifacts, many samples",UPN2_032,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),2536,43,2591,"0,0165959089",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,55","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),8268,138,8462,"0,0163082014",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,33","16,22"
"low bq, low freq, many artifacts, many samples",UPN2_033,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),5310,91,5427,"0,0167680118",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,42","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_034,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),1926,33,1974,"0,0167173252",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,48","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),12755,158,12984,"0,0121688232",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,39","16,35"
"low bq, low freq, many artifacts, many samples",UPN2_048,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),13066,152,13306,"0,011423418",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,37","16,29"
"low bq, low freq, many artifacts, many samples",UPN2_035,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),6876,99,7019,"0,0141045733",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,6","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_036,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),9382,139,9583,"0,0145048523",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,55","15,75"
"low bq, low freq, many artifacts, many samples",UPN2_006,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),2514,32,2558,"0,0125097733",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,24","15,84"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),8602,137,8806,"0,0155575744",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,16","15,57"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),8129,102,8315,"0,0122669874",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,44","16,63"
"low bq, low freq, many artifacts, many samples",UPN2_037,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),11976,165,12201,"0,0135234817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,66","15,6"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),6604,80,6729,"0,0118888394",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,46","15,85"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),7150,87,7280,"0,0119505495",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,48","15,74"
"low bq, low freq, many artifacts, many samples",UPN2_038,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),11610,178,11866,"0,0150008427",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,54","15,7"
"low bq, low freq, many artifacts, many samples",UPN2_039,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),9895,151,10095,"0,0149579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,58","15,99"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),9266,156,9482,"0,0164522253",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,28","15,89"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),6118,79,6230,"0,0126805778",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,53","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),9256,120,9446,"0,01270379",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,28","15,62"
"low bq, low freq, many artifacts, many samples",UPN2_056,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),5165,54,5257,"0,0102720183",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,37","15,8"
"low bq, low freq, many artifacts, many samples",UPN2_090,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),4284,49,4347,"0,0112721417",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,95","18,35"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),7789,96,7942,"0,0120876354",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,44","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),9387,121,9564,"0,0126516102",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,4","16,38"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),15948,341,16396,"0,0207977556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,32","19,45"
"low bq, no database",UPN2_060,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),9183,219,9464,"0,0231403212",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,"0,016",Damaging,"34,25","20,75"
"low bq, low freq, many artifacts, many samples",UPN2_040,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),3971,66,4056,"0,0162721893",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,58","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_091,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),4348,57,4422,"0,012890095",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,78","17,61"
"low bq, low freq, many artifacts, many samples",UPN2_092,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),2381,38,2428,"0,0156507414",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"35,01","16,89"
"low bq, many samples",UPN2_061,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),9247,214,9524,"0,0224695506",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,26","20,26"
"low bq, no database",UPN2_062,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),8272,240,8546,"0,0280833138",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,"0,016",Damaging,"34,3","19,5"
"low bq, many samples",UPN2_063,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),9096,221,9359,"0,0236136339",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,18","20,67"
"low bq, no database",UPN2_064,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),14167,341,14585,"0,0233801851",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,"0,016",Damaging,"34,2","20,63"
"low bq, no database",UPN2_065,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),12069,307,12452,"0,0246546739",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,"0,016",Damaging,"34,11","20,5"
"low bq, many samples",UPN2_066,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),13208,301,13586,"0,0221551597",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,25","20,27"
"low bq, no database",UPN2_067,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),12295,302,12650,"0,0238735178",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,"0,016",Damaging,"34,31","21,76"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),9211,194,9456,"0,0205160745",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,2","20,37"
"low bq, no database",UPN2_069,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),11128,288,11477,"0,0250936656",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,"0,016",Damaging,"34,21","21,05"
"low bq, no database",UPN2_070,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),6748,175,6950,"0,0251798561",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,"0,016",Damaging,"34,19","20,72"
"low bq, no database",UPN2_071,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),5861,138,6041,"0,0228439",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,"0,016",Damaging,"34,16","21,64"
"low bq, no database",UPN2_072,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),8165,170,8378,"0,020291239",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,"0,016",Damaging,"34,12","22,22"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),8032,179,8245,"0,0217101273",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,29","20,86"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),6603,125,6760,"0,0184911243",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,29","20,7"
"low bq, no database",UPN2_075,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),10497,218,10773,"0,0202357746",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,"0,016",Damaging,"34,34","21,59"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),8535,188,8768,"0,0214416058",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,23","20,65"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),11105,243,11421,"0,0212765957",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,36","20,13"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),9202,202,9464,"0,0213440406",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,23","20,49"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),6204,122,6355,"0,0191974823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,31","20,9"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),9121,205,9373,"0,0218713326",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,31","20,81"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),15405,290,15793,"0,0183625657",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,3","21,44"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),12287,240,12606,"0,0190385531",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,32","20,27"
"low bq, no database",UPN2_083,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),10708,291,11054,"0,0263253121",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,"0,016",Damaging,"34,13","20,77"
"low bq, no database",UPN2_084,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),11099,233,11391,"0,020454745",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,"0,016",Damaging,"34,3","21,22"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),9221,184,9459,"0,0194523734",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,27","20,07"
"low bq, many samples",UPN2_086,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),6407,162,6609,"0,0245120291",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,28","20,61"
"low bq, low freq, many artifacts, many samples",UPN2_087,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),13003,208,13285,"0,0156567557",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,22","20,9"
"low bq, no database",UPN2_088,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),10024,237,10312,"0,0229829325",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,"0,016",Damaging,"34,27","20,91"
"low bq, low freq, many artifacts, many samples",UPN2_095,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),4339,64,4425,"0,0144632768",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,9","16,86"
"low bq, low freq, many artifacts, many samples",UPN2_098,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),4418,67,4500,"0,0148888889",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"35,07","18,82"
"low bq, low freq, many artifacts, many samples",UPN2_099,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),2345,32,2384,"0,0134228188",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"35,12","20,81"
"low bq, low freq, many artifacts, many samples",UPN2_101,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),4347,45,4408,"0,0102087114",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"35,05","18,2"
"low bq, low freq, many artifacts, many samples",UPN2_102,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),4384,68,4472,"0,0152057245",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"35,01","19,31"
"low bq, low freq, many artifacts, many samples",UPN2_103,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),4131,42,4181,"0,0100454437",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"35,06","17,88"
"low bq, low freq, many artifacts, many samples",UPN2_105,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),4881,53,4948,"0,0107113985",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"35,06","18,42"
"low bq, low freq, many artifacts, many samples",UPN2_106,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),6501,67,6592,"0,010163835",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,96","16,34"
"low bq, low freq, many artifacts, many samples",UPN2_110,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),6188,64,6279,"0,0101927058",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,35,"16,69"
"low bq, low freq, many artifacts",UPN2_111,2,25464483,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His677Pro/c.2030A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),5655,81,5768,"0,0140429958",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,29",Deleterious,16,Damaging,"34,92","18,15"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_059,2,25464489,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val675Gly/c.2024T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),30385,404,30971,"0,0130444609",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,59",Deleterious,11,Damaging,"25,05","14,72"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_060,2,25464489,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val675Gly/c.2024T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17441,245,17797,"0,0137663651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,59",Deleterious,11,Damaging,"25,11","14,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,2,25464489,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val675Gly/c.2024T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17558,220,17949,"0,0122569502",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,59",Deleterious,11,Damaging,"24,69","15,12"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,2,25464489,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val675Gly/c.2024T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),15681,241,16034,"0,0150305601",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,59",Deleterious,11,Damaging,"24,67","14,61"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,2,25464489,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val675Gly/c.2024T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17164,276,17578,"0,015701445",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,59",Deleterious,11,Damaging,"24,94","15,01"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,2,25464489,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val675Gly/c.2024T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),26848,367,27424,"0,0133824387",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,59",Deleterious,11,Damaging,"24,98","14,91"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_065,2,25464489,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val675Gly/c.2024T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),22802,321,23307,"0,0137726863",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,59",Deleterious,11,Damaging,"25,14","14,79"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_066,2,25464489,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val675Gly/c.2024T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),24931,337,25476,"0,0132281363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,59",Deleterious,11,Damaging,"25,18","14,69"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_067,2,25464489,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val675Gly/c.2024T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),23272,259,23724,"0,0109172146",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,59",Deleterious,11,Damaging,"25,49","14,64"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_068,2,25464489,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val675Gly/c.2024T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17404,258,17786,"0,0145057911",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,59",Deleterious,11,Damaging,"24,67","14,67"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_069,2,25464489,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val675Gly/c.2024T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),20996,338,21490,"0,0157282457",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,59",Deleterious,11,Damaging,"24,79","14,53"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_070,2,25464489,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val675Gly/c.2024T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),12693,200,13001,"0,015383432",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,59",Deleterious,11,Damaging,"24,63","14,24"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,2,25464489,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val675Gly/c.2024T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),11066,166,11313,"0,0146733846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,59",Deleterious,11,Damaging,25,"14,77"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,2,25464489,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val675Gly/c.2024T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),15440,204,15757,"0,0129466269",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,59",Deleterious,11,Damaging,"25,03","14,5"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,2,25464489,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val675Gly/c.2024T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),15223,203,15525,"0,0130756844",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,59",Deleterious,11,Damaging,"25,16","15,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,2,25464489,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val675Gly/c.2024T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),12541,165,12797,"0,0128936469",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,59",Deleterious,11,Damaging,"25,1","15,01"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_075,2,25464489,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val675Gly/c.2024T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),19956,247,20362,"0,0121304391",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,59",Deleterious,11,Damaging,"25,4","14,74"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,2,25464489,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val675Gly/c.2024T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),16221,256,16594,"0,0154272629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,59",Deleterious,11,Damaging,"24,65","14,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,2,25464489,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val675Gly/c.2024T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),21126,317,21619,"0,0146630279",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,59",Deleterious,11,Damaging,"24,82","14,73"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,2,25464489,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val675Gly/c.2024T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17441,248,17811,"0,0139239796",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,59",Deleterious,11,Damaging,"24,63","14,47"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_079,2,25464489,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val675Gly/c.2024T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),11762,170,12021,"0,0141419183",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,59",Deleterious,11,Damaging,"25,1","14,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,2,25464489,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val675Gly/c.2024T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17313,235,17706,"0,0132723371",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,59",Deleterious,11,Damaging,"25,02","14,84"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_081,2,25464489,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val675Gly/c.2024T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),29289,381,29908,"0,0127390665",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,59",Deleterious,11,Damaging,"25,16","14,43"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_082,2,25464489,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val675Gly/c.2024T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),23280,302,23787,"0,0126960104",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,59",Deleterious,11,Damaging,"25,13","14,74"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,2,25464489,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val675Gly/c.2024T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),20193,307,20668,"0,0148538804",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,59",Deleterious,11,Damaging,"24,61","14,46"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,2,25464489,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val675Gly/c.2024T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),21073,310,21548,"0,014386486",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,59",Deleterious,11,Damaging,"24,67","14,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_085,2,25464489,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val675Gly/c.2024T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17511,248,17884,"0,0138671438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,59",Deleterious,11,Damaging,"24,94","15,04"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,2,25464489,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val675Gly/c.2024T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),12139,161,12419,"0,0129640068",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,59",Deleterious,11,Damaging,"24,72","14,93"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_087,2,25464489,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val675Gly/c.2024T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),24620,341,25169,"0,0135484127",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,59",Deleterious,11,Damaging,"25,17","14,72"
"low bq, bad alignment, low freq, many artifacts",UPN2_088,2,25464489,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val675Gly/c.2024T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),18997,215,19355,"0,0111082408",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,59",Deleterious,11,Damaging,"25,44","14,63"
"not in 2nd Illumina, low freq, no database",UPN2_004,2,25464489,A,G,missense_variant(MODERATE|MISSENSE|gTg/gCg|p.Val675Ala/c.2024T>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),2032,23,2062,"0,0111542192",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,73",Deleterious,"0,131",Tolerated,"25,24","30,78"
"not in 2nd Illumina, low freq, no database",UPN2_006,2,25464489,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val675Glu/c.2024T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|T),4703,68,4787,"0,0142051389",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,63",Deleterious,"0,013",Damaging,"25,68","26,38"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,25464492,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met674Arg/c.2021T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),30480,365,30995,"0,0117760929",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,31",Neutral,265,Tolerated,"29,15","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25464492,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met674Arg/c.2021T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17489,213,17808,"0,0119609164",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,31",Neutral,265,Tolerated,"29,23","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25464492,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met674Arg/c.2021T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17658,226,17967,"0,0125786164",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,31",Neutral,265,Tolerated,"28,97","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25464492,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met674Arg/c.2021T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),15762,203,16041,"0,0126550714",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,31",Neutral,265,Tolerated,"28,65","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25464492,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met674Arg/c.2021T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17254,232,17587,"0,0131915619",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,31",Neutral,265,Tolerated,"29,06","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25464492,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met674Arg/c.2021T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),26980,334,27454,"0,0121658046",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,31",Neutral,265,Tolerated,"29,02","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,25464492,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met674Arg/c.2021T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),22926,283,23320,"0,012135506",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,31",Neutral,265,Tolerated,"29,21","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_066,2,25464492,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met674Arg/c.2021T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),25057,284,25491,"0,0111411871",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,31",Neutral,265,Tolerated,"29,24","15,31"
"low bq, low freq, many artifacts, many samples",UPN2_067,2,25464492,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met674Arg/c.2021T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),23370,247,23736,"0,0104061341",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,31",Neutral,265,Tolerated,"29,47","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25464492,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met674Arg/c.2021T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17487,239,17799,"0,0134277207",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,31",Neutral,265,Tolerated,"28,73","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25464492,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met674Arg/c.2021T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),21088,272,21499,"0,0126517512",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,31",Neutral,265,Tolerated,"28,97","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,25464492,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met674Arg/c.2021T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),12758,194,13011,"0,0149104604",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,31",Neutral,265,Tolerated,"28,73","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25464492,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met674Arg/c.2021T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),11144,122,11318,"0,0107792896",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,31",Neutral,265,Tolerated,"29,01","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25464492,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met674Arg/c.2021T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),15493,184,15767,"0,0116699436",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,31",Neutral,265,Tolerated,"29,08","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25464492,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met674Arg/c.2021T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),15271,173,15537,"0,0111347107",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,31",Neutral,265,Tolerated,"29,21","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,25464492,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met674Arg/c.2021T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),12595,134,12806,"0,0104638451",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,31",Neutral,265,Tolerated,"29,15","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25464492,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met674Arg/c.2021T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),20046,210,20371,"0,0103087723",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,31",Neutral,265,Tolerated,"29,37","15,37"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25464492,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met674Arg/c.2021T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),16289,219,16605,"0,0131887986",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,31",Neutral,265,Tolerated,"28,65","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25464492,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met674Arg/c.2021T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),21250,263,21634,"0,0121567902",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,31",Neutral,265,Tolerated,"28,82","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25464492,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met674Arg/c.2021T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17466,235,17831,"0,0131792945",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,31",Neutral,265,Tolerated,"28,7","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25464492,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met674Arg/c.2021T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),11808,128,12024,"0,0106453759",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,31",Neutral,265,Tolerated,"29,08","15,34"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25464492,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met674Arg/c.2021T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17404,231,17718,"0,0130375889",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,31",Neutral,265,Tolerated,"29,07","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25464492,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met674Arg/c.2021T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),29327,391,29930,"0,0130638156",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,31",Neutral,265,Tolerated,"29,28","15,34"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25464492,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met674Arg/c.2021T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),23418,269,23806,"0,0112996724",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,31",Neutral,265,Tolerated,"29,24","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25464492,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met674Arg/c.2021T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),20276,320,20685,"0,0154701474",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,31",Neutral,265,Tolerated,"28,7","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25464492,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met674Arg/c.2021T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),21152,299,21562,"0,0138669882",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,31",Neutral,265,Tolerated,"28,76","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,25464492,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met674Arg/c.2021T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17609,200,17899,"0,0111738086",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,31",Neutral,265,Tolerated,"28,87","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_086,2,25464492,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met674Arg/c.2021T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),12221,141,12431,"0,0113426112",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,31",Neutral,265,Tolerated,"28,76","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_087,2,25464492,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met674Arg/c.2021T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),24761,315,25190,"0,0125049623",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,31",Neutral,265,Tolerated,"29,11","14,79"
"low bq, low freq, many artifacts",UPN2_088,2,25464492,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met674Arg/c.2021T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),19066,202,19371,"0,0104279593",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,31",Neutral,265,Tolerated,"29,38",15
"low bq, bad alignment, many samples",UPN2_059,2,25464498,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val672Gly/c.2015T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),29995,785,31002,"0,025320947",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,1,Damaging,"25,68","14,82"
"low bq, bad alignment, many samples",UPN2_060,2,25464498,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val672Gly/c.2015T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17257,428,17816,"0,0240233498",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,1,Damaging,"25,59","14,71"
"low bq, bad alignment, many samples",UPN2_061,2,25464498,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val672Gly/c.2015T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17362,489,17973,"0,0272074779",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,1,Damaging,"25,34","14,95"
"low bq, bad alignment, many samples",UPN2_062,2,25464498,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val672Gly/c.2015T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),15427,474,16048,"0,0295363908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,1,Damaging,"25,12","14,63"
"low bq, bad alignment, many samples",UPN2_063,2,25464498,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val672Gly/c.2015T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),16943,524,17593,"0,0297845734",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,1,Damaging,"25,53","15,05"
"low bq, bad alignment, many samples",UPN2_064,2,25464498,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val672Gly/c.2015T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),26507,769,27463,"0,0280013109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,1,Damaging,"25,58","14,77"
"low bq, bad alignment, many samples",UPN2_065,2,25464498,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val672Gly/c.2015T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),22522,629,23325,"0,0269667738",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,1,Damaging,"25,73","14,62"
"low bq, bad alignment, many samples",UPN2_066,2,25464498,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val672Gly/c.2015T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),24649,662,25504,"0,0259567127",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,1,Damaging,"25,77","15,06"
"low bq, bad alignment, many samples",UPN2_067,2,25464498,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val672Gly/c.2015T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),23043,567,23746,"0,0238777057",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,1,Damaging,"25,94","14,83"
"low bq, bad alignment, many samples",UPN2_068,2,25464498,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val672Gly/c.2015T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17123,561,17808,"0,0315026954",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,1,Damaging,"25,28","15,12"
"low bq, bad alignment, many samples",UPN2_069,2,25464498,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val672Gly/c.2015T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),20749,605,21510,"0,0281264528",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,1,Damaging,"25,4","14,57"
"low bq, bad alignment, many samples",UPN2_070,2,25464498,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val672Gly/c.2015T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),12522,377,13013,"0,028971029",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,1,Damaging,"25,17","14,98"
"low bq, bad alignment, many samples",UPN2_071,2,25464498,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val672Gly/c.2015T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),10919,310,11329,"0,0273634037",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,1,Damaging,"25,42","14,56"
"low bq, bad alignment, many samples",UPN2_072,2,25464498,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val672Gly/c.2015T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),15268,375,15771,"0,02377782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,1,Damaging,"25,53","14,76"
"low bq, bad alignment, many samples",UPN2_073,2,25464498,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val672Gly/c.2015T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),14996,411,15547,"0,0264359684",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,1,Damaging,"25,75","14,64"
"low bq, bad alignment, many samples",UPN2_074,2,25464498,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val672Gly/c.2015T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),12400,309,12811,"0,024119897",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,1,Damaging,"25,6","15,13"
"low bq, bad alignment, many samples",UPN2_075,2,25464498,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val672Gly/c.2015T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),19760,485,20372,"0,0238071863",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,1,Damaging,"25,94","14,68"
"low bq, bad alignment, many samples",UPN2_076,2,25464498,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val672Gly/c.2015T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),15996,517,16614,"0,0311183339",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,1,Damaging,"25,21","14,79"
"low bq, bad alignment, many samples",UPN2_077,2,25464498,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val672Gly/c.2015T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),20877,575,21629,"0,026584678",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,1,Damaging,"25,34","14,67"
"low bq, bad alignment, many samples",UPN2_078,2,25464498,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val672Gly/c.2015T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17207,504,17845,"0,0282432054",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,1,Damaging,"25,17","14,92"
"low bq, bad alignment, many samples",UPN2_079,2,25464498,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val672Gly/c.2015T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),11649,298,12027,"0,0247775838",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,1,Damaging,"25,56","14,82"
"low bq, bad alignment, many samples",UPN2_080,2,25464498,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val672Gly/c.2015T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17101,481,17730,"0,0271291596",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,1,Damaging,"25,55","15,05"
"low bq, bad alignment, many samples",UPN2_081,2,25464498,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val672Gly/c.2015T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),28890,790,29936,"0,0263896312",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,1,Damaging,"25,82","15,11"
"low bq, bad alignment, many samples",UPN2_082,2,25464498,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val672Gly/c.2015T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),23055,566,23812,"0,023769528",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,1,Damaging,"25,77","14,91"
"low bq, bad alignment, many samples",UPN2_083,2,25464498,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val672Gly/c.2015T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),19879,655,20696,"0,0316486278",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,1,Damaging,25,"14,53"
"low bq, bad alignment, many samples",UPN2_084,2,25464498,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val672Gly/c.2015T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),20777,641,21572,"0,0297144447",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,1,Damaging,"25,19","14,76"
"low bq, bad alignment, many samples",UPN2_085,2,25464498,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val672Gly/c.2015T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17281,484,17911,"0,0270225001",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,1,Damaging,"25,49","15,04"
"low bq, bad alignment, many samples",UPN2_086,2,25464498,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val672Gly/c.2015T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),11994,347,12435,"0,0279051066",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,1,Damaging,"25,07","14,69"
"low bq, bad alignment, many samples",UPN2_087,2,25464498,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val672Gly/c.2015T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),24363,631,25197,"0,0250426638",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,1,Damaging,"25,53","14,88"
"low bq, bad alignment",UPN2_088,2,25464498,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val672Gly/c.2015T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),18754,470,19378,"0,024254309",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,1,Damaging,"25,93","15,6"
"low bq, bad alignment, low freq, many artifacts",UPN2_054,2,25464498,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val672Glu/c.2015T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|T),11570,138,11826,"0,0116692035",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,66",Deleterious,16,Damaging,"25,95","21,49"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,25464502,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr671Pro/c.2011A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),30534,346,31032,"0,0111497809",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,8,Damaging,"29,02","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25464502,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr671Pro/c.2011A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),17513,204,17828,"0,0114426744",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,8,Damaging,"28,95","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25464502,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr671Pro/c.2011A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),17662,210,17988,"0,0116744496",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,8,Damaging,"28,79","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25464502,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr671Pro/c.2011A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),15796,174,16057,"0,0108363953",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,8,Damaging,"28,45","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25464502,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr671Pro/c.2011A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),17329,182,17606,"0,010337385",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,8,Damaging,"28,9","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25464502,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr671Pro/c.2011A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),26991,314,27485,"0,0114244133",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,8,Damaging,"28,94","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,25464502,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr671Pro/c.2011A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),22965,254,23342,"0,0108816725",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,8,Damaging,"29,09","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_067,2,25464502,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr671Pro/c.2011A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),23360,245,23762,"0,0103105799",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,8,Damaging,"29,33","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25464502,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr671Pro/c.2011A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),17492,208,17820,"0,0116722783",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,8,Damaging,"28,74","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25464502,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr671Pro/c.2011A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),21133,254,21520,"0,011802974",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,8,Damaging,"28,84","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,25464502,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr671Pro/c.2011A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),12800,158,13019,"0,0121361088",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,8,Damaging,"28,71","14,09"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25464502,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr671Pro/c.2011A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),11133,131,11341,"0,0115510096",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,8,Damaging,"28,99","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25464502,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr671Pro/c.2011A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),15525,169,15785,"0,0107063668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,8,Damaging,"29,07","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25464502,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr671Pro/c.2011A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),15321,165,15557,"0,010606158",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,8,Damaging,"29,03","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,25464502,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr671Pro/c.2011A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),12597,167,12818,"0,0130285536",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,8,Damaging,"28,85","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25464502,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr671Pro/c.2011A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),20042,223,20387,"0,0109383431",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,8,Damaging,"29,28","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25464502,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr671Pro/c.2011A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),21278,236,21643,"0,0109042185",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,8,Damaging,"28,74","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25464502,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr671Pro/c.2011A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),17569,208,17859,"0,0116467887",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,8,Damaging,"28,61","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25464502,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr671Pro/c.2011A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),11841,127,12031,"0,0105560635",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,8,Damaging,"28,96","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25464502,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr671Pro/c.2011A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),23450,257,23829,"0,0107851777",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,8,Damaging,"29,03","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25464502,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr671Pro/c.2011A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),20327,231,20699,"0,0111599594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,8,Damaging,"28,53","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25464502,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr671Pro/c.2011A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),21246,226,21577,"0,010474116",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,8,Damaging,"28,74","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,25464502,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr671Pro/c.2011A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),17608,210,17921,"0,0117180961",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,8,Damaging,"28,85","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_086,2,25464502,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr671Pro/c.2011A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),12238,128,12442,"0,0102877351",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,8,Damaging,"28,69","15,88"
"low bq, low freq, many artifacts, many samples",UPN2_087,2,25464502,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr671Pro/c.2011A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),24814,267,25215,"0,0105889352",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,8,Damaging,"29,06","14,91"
"low bq, low freq, many artifacts",UPN2_088,2,25464502,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr671Pro/c.2011A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),19084,199,19401,"0,0102572032",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,8,Damaging,"29,24",15
"low bq, low freq, many artifacts, many samples",UPN2_059,2,25464505,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile670Leu/c.2008A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),30539,382,31039,"0,0123070975",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,93",Neutral,165,Tolerated,"29,39","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25464505,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile670Leu/c.2008A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),17518,230,17829,"0,0129003309",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,93",Neutral,165,Tolerated,"29,24","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25464505,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile670Leu/c.2008A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),17687,224,17990,"0,0124513619",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,93",Neutral,165,Tolerated,"29,2","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25464505,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile670Leu/c.2008A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),15775,218,16059,"0,0135749424",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,93",Neutral,165,Tolerated,"28,86","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25464505,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile670Leu/c.2008A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),17313,213,17608,"0,0120967742",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,93",Neutral,165,Tolerated,"29,23","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25464505,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile670Leu/c.2008A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),27003,342,27484,"0,0124436036",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,93",Neutral,165,Tolerated,"29,27","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,25464505,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile670Leu/c.2008A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),22990,273,23348,"0,0116926503",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,93",Neutral,165,Tolerated,"29,48","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_066,2,25464505,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile670Leu/c.2008A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),25096,318,25528,"0,0124569101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,93",Neutral,165,Tolerated,"29,44","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_067,2,25464505,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile670Leu/c.2008A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),23396,261,23768,"0,0109811511",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,93",Neutral,165,Tolerated,"29,69","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25464505,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile670Leu/c.2008A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),17504,239,17826,"0,0134073825",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,93",Neutral,165,Tolerated,"29,08","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25464505,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile670Leu/c.2008A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),21186,247,21527,"0,0114739629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,93",Neutral,165,Tolerated,"29,24","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,25464505,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile670Leu/c.2008A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),12788,163,13021,"0,0125182398",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,93",Neutral,165,Tolerated,"29,05","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25464505,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile670Leu/c.2008A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),11164,141,11348,"0,0124250969",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,93",Neutral,165,Tolerated,"29,26","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25464505,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile670Leu/c.2008A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),15533,169,15786,"0,0107056886",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,93",Neutral,165,Tolerated,"29,41","14,08"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25464505,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile670Leu/c.2008A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),15309,193,15560,"0,012403599",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,93",Neutral,165,Tolerated,"29,41","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,25464505,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile670Leu/c.2008A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),12616,151,12819,"0,01177939",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,93",Neutral,165,Tolerated,"29,33","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25464505,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile670Leu/c.2008A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),20071,206,20388,"0,0101039827",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,93",Neutral,165,Tolerated,"29,54","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25464505,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile670Leu/c.2008A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),16323,230,16627,"0,0138329224",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,93",Neutral,165,Tolerated,"29,01","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25464505,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile670Leu/c.2008A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),21292,260,21653,"0,012007574",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,93",Neutral,165,Tolerated,"29,18","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25464505,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile670Leu/c.2008A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),17546,236,17862,"0,0132124062",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,93",Neutral,165,Tolerated,"28,9","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25464505,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile670Leu/c.2008A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),11843,136,12034,"0,0113013129",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,93",Neutral,165,Tolerated,"29,38","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25464505,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile670Leu/c.2008A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),17448,215,17738,"0,0121208704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,93",Neutral,165,Tolerated,"29,32","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25464505,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile670Leu/c.2008A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),29536,320,29966,"0,0106787693",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,93",Neutral,165,Tolerated,"29,59","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25464505,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile670Leu/c.2008A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),23454,266,23834,"0,011160527",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,93",Neutral,165,Tolerated,"29,41","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25464505,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile670Leu/c.2008A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),20357,267,20702,"0,0128973046",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,93",Neutral,165,Tolerated,"28,91","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25464505,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile670Leu/c.2008A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),21207,278,21584,"0,012879911",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,93",Neutral,165,Tolerated,"29,2","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,25464505,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile670Leu/c.2008A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),17639,204,17922,"0,0113826582",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,93",Neutral,165,Tolerated,"29,29","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_086,2,25464505,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile670Leu/c.2008A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),12232,155,12451,"0,0124487993",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,93",Neutral,165,Tolerated,"29,18","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_087,2,25464505,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile670Leu/c.2008A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),24779,310,25220,"0,0122918319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,93",Neutral,165,Tolerated,"29,41","14,44"
"low bq, low freq, many artifacts",UPN2_088,2,25464505,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile670Leu/c.2008A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),19097,245,19403,"0,0126269134",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,93",Neutral,165,Tolerated,"29,54","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,25464510,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp668Ala/c.2003A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),30480,384,31042,"0,012370337",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,11",Deleterious,64,Tolerated,"28,36","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25464510,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp668Ala/c.2003A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),17512,218,17833,"0,0122245276",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,11",Deleterious,64,Tolerated,"28,25","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25464510,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp668Ala/c.2003A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),17704,205,17993,"0,0113933196",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,11",Deleterious,64,Tolerated,"28,05","15,17"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25464510,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp668Ala/c.2003A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),15761,190,16063,"0,0118284256",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,11",Deleterious,64,Tolerated,"27,78","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25464510,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp668Ala/c.2003A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),17284,234,17611,"0,0132871501",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,11",Deleterious,64,Tolerated,"28,19","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25464510,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp668Ala/c.2003A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),27025,323,27489,"0,0117501546",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,11",Deleterious,64,Tolerated,"28,21","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,25464510,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp668Ala/c.2003A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),22968,246,23348,"0,0105362344",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,11",Deleterious,64,Tolerated,"28,42","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_066,2,25464510,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp668Ala/c.2003A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),25059,299,25531,"0,011711253",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,11",Deleterious,64,Tolerated,"28,44","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_067,2,25464510,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp668Ala/c.2003A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),23388,249,23771,"0,0104749485",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,11",Deleterious,64,Tolerated,"28,55","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25464510,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp668Ala/c.2003A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),17488,224,17829,"0,0125638005",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,11",Deleterious,64,Tolerated,"27,96","15,59"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25464510,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp668Ala/c.2003A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),21133,263,21531,"0,0122149459",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,11",Deleterious,64,Tolerated,"28,07","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,25464510,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp668Ala/c.2003A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),12763,184,13026,"0,014125595",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,11",Deleterious,64,Tolerated,"27,88","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25464510,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp668Ala/c.2003A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),11147,140,11348,"0,0123369757",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,11",Deleterious,64,Tolerated,"28,3","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25464510,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp668Ala/c.2003A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),15556,163,15789,"0,010323643",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,11",Deleterious,64,Tolerated,"28,38","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25464510,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp668Ala/c.2003A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),15316,181,15564,"0,0116294012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,11",Deleterious,64,Tolerated,"28,3","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,25464510,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp668Ala/c.2003A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),12586,151,12821,"0,0117775525",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,11",Deleterious,64,Tolerated,"28,18","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25464510,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp668Ala/c.2003A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),20041,233,20396,"0,0114238086",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,11",Deleterious,64,Tolerated,"28,46","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25464510,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp668Ala/c.2003A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),16320,208,16628,"0,0125090209",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,11",Deleterious,64,Tolerated,"27,83","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25464510,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp668Ala/c.2003A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),21271,256,21657,"0,0118206584",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,11",Deleterious,64,Tolerated,"27,98","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25464510,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp668Ala/c.2003A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),17537,214,17864,"0,0119793999",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,11",Deleterious,64,Tolerated,"27,8","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25464510,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp668Ala/c.2003A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),11835,140,12035,"0,0116327378",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,11",Deleterious,64,Tolerated,"28,24","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25464510,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp668Ala/c.2003A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),17461,204,17740,"0,0114994363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,11",Deleterious,64,Tolerated,"28,25","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25464510,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp668Ala/c.2003A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),29472,366,29969,"0,0122126197",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,11",Deleterious,64,Tolerated,"28,46","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25464510,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp668Ala/c.2003A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),23425,286,23835,"0,0119991609",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,11",Deleterious,64,Tolerated,"28,38","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25464510,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp668Ala/c.2003A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),20322,276,20705,"0,0133301135",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,11",Deleterious,64,Tolerated,"27,83","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25464510,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp668Ala/c.2003A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),21211,262,21584,"0,0121386212",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,11",Deleterious,64,Tolerated,"27,99","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,25464510,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp668Ala/c.2003A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),17637,195,17927,"0,0108774474",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,11",Deleterious,64,Tolerated,"28,23","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_086,2,25464510,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp668Ala/c.2003A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),12230,155,12452,"0,0124477996",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,11",Deleterious,64,Tolerated,28,"15,22"
"low bq, low freq, many artifacts, many samples",UPN2_087,2,25464510,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp668Ala/c.2003A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),24781,283,25222,"0,0112203632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,11",Deleterious,64,Tolerated,"28,41","15,41"
"low bq, low freq, many artifacts",UPN2_088,2,25464510,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp668Ala/c.2003A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),19110,208,19407,"0,0107177822",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,11",Deleterious,64,Tolerated,"28,49","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,25464515,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys666Trp/c.1998T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),30184,655,31010,"0,0211222186",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,32",Deleterious,15,Damaging,"27,81","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25464515,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys666Trp/c.1998T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17312,379,17803,"0,0212885469",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,32",Deleterious,15,Damaging,"27,92","14,79"
"low bq, many samples",UPN2_061,2,25464515,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys666Trp/c.1998T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17479,404,17985,"0,0224631637",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,32",Deleterious,15,Damaging,"27,6","14,91"
"low bq, many samples",UPN2_062,2,25464515,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys666Trp/c.1998T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),15569,381,16046,"0,0237442353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,32",Deleterious,15,Damaging,"27,35","14,73"
"low bq, many samples",UPN2_063,2,25464515,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys666Trp/c.1998T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17087,391,17580,"0,0222411832",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,32",Deleterious,15,Damaging,"27,83","14,85"
"low bq, many samples",UPN2_064,2,25464515,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys666Trp/c.1998T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),26620,649,27441,"0,0236507416",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,32",Deleterious,15,Damaging,"27,76","14,87"
"low bq, many samples",UPN2_065,2,25464515,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys666Trp/c.1998T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),22621,522,23321,"0,0223832597",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,32",Deleterious,15,Damaging,"27,81","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_066,2,25464515,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys666Trp/c.1998T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),24832,509,25492,"0,0199670485",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,32",Deleterious,15,Damaging,28,"14,81"
"low bq, low freq, many artifacts, many samples",UPN2_067,2,25464515,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys666Trp/c.1998T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),23172,457,23742,"0,019248589",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,32",Deleterious,15,Damaging,"28,27","14,94"
"low bq, many samples",UPN2_068,2,25464515,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys666Trp/c.1998T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17254,446,17805,"0,0250491435",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,32",Deleterious,15,Damaging,"27,34","14,93"
"low bq, many samples",UPN2_069,2,25464515,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys666Trp/c.1998T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),20858,499,21485,"0,0232255062",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,32",Deleterious,15,Damaging,"27,67","14,79"
"low bq, many samples",UPN2_070,2,25464515,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys666Trp/c.1998T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),12600,319,12996,"0,0245460142",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,32",Deleterious,15,Damaging,"27,44","14,79"
"low bq, many samples",UPN2_071,2,25464515,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys666Trp/c.1998T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),10958,279,11338,"0,0246075146",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,32",Deleterious,15,Damaging,"27,74","14,56"
"low bq, many samples",UPN2_072,2,25464515,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys666Trp/c.1998T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),15313,351,15763,"0,0222673349",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,32",Deleterious,15,Damaging,"27,86","14,62"
"low bq, many samples",UPN2_073,2,25464515,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys666Trp/c.1998T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),15109,351,15546,"0,0225781552",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,32",Deleterious,15,Damaging,"27,83","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,25464515,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys666Trp/c.1998T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),12474,245,12797,"0,0191451121",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,32",Deleterious,15,Damaging,"27,94","15,37"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25464515,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys666Trp/c.1998T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),19833,405,20374,"0,0198782762",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,32",Deleterious,15,Damaging,"28,22","14,92"
"low bq, many samples",UPN2_076,2,25464515,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys666Trp/c.1998T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),16108,400,16587,"0,024115271",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,32",Deleterious,15,Damaging,"27,33","14,8"
"low bq, many samples",UPN2_077,2,25464515,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys666Trp/c.1998T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),21016,506,21640,"0,0233826248",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,32",Deleterious,15,Damaging,"27,71","15,12"
"low bq, many samples",UPN2_078,2,25464515,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys666Trp/c.1998T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17249,486,17849,"0,0272284162",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,32",Deleterious,15,Damaging,"27,42","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25464515,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys666Trp/c.1998T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),11719,224,12011,"0,0186495712",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,32",Deleterious,15,Damaging,"27,77","15,23"
"low bq, many samples",UPN2_080,2,25464515,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys666Trp/c.1998T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17212,397,17717,"0,0224078569",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,32",Deleterious,15,Damaging,"27,76","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25464515,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys666Trp/c.1998T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),29116,656,29924,"0,0219222029",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,32",Deleterious,15,Damaging,"28,02","14,89"
"low bq, many samples",UPN2_082,2,25464515,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys666Trp/c.1998T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),23095,547,23795,"0,0229880227",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,32",Deleterious,15,Damaging,"28,03","14,61"
"low bq, many samples",UPN2_083,2,25464515,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys666Trp/c.1998T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),20024,554,20686,"0,026781398",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,32",Deleterious,15,Damaging,"27,34","14,72"
"low bq, many samples",UPN2_084,2,25464515,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys666Trp/c.1998T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),20867,575,21548,"0,0266846111",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,32",Deleterious,15,Damaging,"27,43","15,77"
"low bq, many samples",UPN2_085,2,25464515,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys666Trp/c.1998T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17381,411,17900,"0,0229608939",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,32",Deleterious,15,Damaging,"27,62","14,44"
"low bq, many samples",UPN2_086,2,25464515,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys666Trp/c.1998T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),12081,282,12439,"0,0226706327",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,32",Deleterious,15,Damaging,"27,53","14,52"
"low bq, many samples",UPN2_087,2,25464515,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys666Trp/c.1998T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),24426,588,25175,"0,0233565045",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,32",Deleterious,15,Damaging,"27,83","14,73"
"low bq, low freq, many artifacts",UPN2_088,2,25464515,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys666Trp/c.1998T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),18940,351,19382,"0,0181095862",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,32",Deleterious,15,Damaging,"28,2","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,25464517,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys666Gly/c.1996T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),30381,488,31054,"0,0157145617",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,75",Deleterious,505,Tolerated,"28,77","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25464517,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys666Gly/c.1996T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17408,280,17839,"0,0156959471",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,75",Deleterious,505,Tolerated,"28,89","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25464517,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys666Gly/c.1996T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17611,295,18002,"0,0163870681",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,75",Deleterious,505,Tolerated,"28,58","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25464517,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys666Gly/c.1996T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),15643,317,16069,"0,0197274255",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,75",Deleterious,505,Tolerated,"28,21","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25464517,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys666Gly/c.1996T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17190,313,17614,"0,0177699557",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,75",Deleterious,505,Tolerated,"28,74","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25464517,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys666Gly/c.1996T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),26873,458,27495,"0,0166575741",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,75",Deleterious,505,Tolerated,"28,67","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,25464517,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys666Gly/c.1996T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),22834,361,23359,"0,0154544287",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,75",Deleterious,505,Tolerated,"28,8","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_066,2,25464517,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys666Gly/c.1996T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),24988,368,25532,"0,0144132853",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,75",Deleterious,505,Tolerated,"28,89","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_067,2,25464517,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys666Gly/c.1996T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),23240,369,23779,"0,0155178939",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,75",Deleterious,505,Tolerated,"29,15","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25464517,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys666Gly/c.1996T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17390,330,17837,"0,018500869",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,75",Deleterious,505,Tolerated,"28,29","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25464517,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys666Gly/c.1996T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),20999,363,21537,"0,0168547151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,75",Deleterious,505,Tolerated,"28,61","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,25464517,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys666Gly/c.1996T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),12703,257,13029,"0,0197252283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,75",Deleterious,505,Tolerated,"28,41","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25464517,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys666Gly/c.1996T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),11077,177,11351,"0,0155933398",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,75",Deleterious,505,Tolerated,"28,63","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25464517,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys666Gly/c.1996T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),15463,257,15796,"0,0162699418",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,75",Deleterious,505,Tolerated,"28,76","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25464517,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys666Gly/c.1996T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),15239,241,15565,"0,0154834565",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,75",Deleterious,505,Tolerated,"28,77","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,25464517,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys666Gly/c.1996T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),12561,184,12825,"0,0143469786",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,75",Deleterious,505,Tolerated,"28,86","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25464517,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys666Gly/c.1996T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),19987,294,20401,"0,0144110583",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,75",Deleterious,505,Tolerated,29,"14,94"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25464517,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys666Gly/c.1996T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),16193,300,16630,"0,0180396873",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,75",Deleterious,505,Tolerated,"28,27","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25464517,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys666Gly/c.1996T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),21167,348,21668,"0,0160605501",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,75",Deleterious,505,Tolerated,"28,56","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25464517,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys666Gly/c.1996T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17392,332,17875,"0,0185734266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,75",Deleterious,505,Tolerated,"28,47","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25464517,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys666Gly/c.1996T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),11775,179,12035,"0,0148732862",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,75",Deleterious,505,Tolerated,"28,63","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25464517,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys666Gly/c.1996T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17313,287,17744,"0,0161744815",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,75",Deleterious,505,Tolerated,"28,74","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25464517,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys666Gly/c.1996T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),29333,428,29979,"0,0142766603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,75",Deleterious,505,Tolerated,"28,87","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25464517,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys666Gly/c.1996T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),23261,367,23841,"0,0153936496",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,75",Deleterious,505,Tolerated,"28,88","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25464517,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys666Gly/c.1996T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),20182,379,20713,"0,0182976874",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,75",Deleterious,505,Tolerated,"28,3","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25464517,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys666Gly/c.1996T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),21026,384,21594,"0,0177827174",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,75",Deleterious,505,Tolerated,"28,37","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,25464517,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys666Gly/c.1996T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17518,315,17931,"0,0175673415",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,75",Deleterious,505,Tolerated,"28,7","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_086,2,25464517,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys666Gly/c.1996T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),12153,201,12453,"0,016140689",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,75",Deleterious,505,Tolerated,"28,47","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_087,2,25464517,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys666Gly/c.1996T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),24631,387,25233,"0,0153370586",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,75",Deleterious,505,Tolerated,"28,73","14,71"
"low bq, low freq, many artifacts",UPN2_088,2,25464517,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys666Gly/c.1996T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),19000,294,19413,"0,0151444908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,75",Deleterious,505,Tolerated,"29,14","14,87"
"low bq, many samples",UPN2_059,2,25464519,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val665Gly/c.1994T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),30072,780,31056,"0,0251159196",0,0,0,0,1,0,0,0,1,NO,NO,COSM231559,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,"8,24E-006",NO,NO,"-6,76",Deleterious,1,Damaging,"28,09","14,71"
"low bq, many samples",UPN2_060,2,25464519,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val665Gly/c.1994T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17278,428,17841,"0,0239896867",0,0,0,0,1,0,0,0,1,NO,NO,COSM231559,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,"8,24E-006",NO,NO,"-6,76",Deleterious,1,Damaging,"28,13","15,11"
"low bq, many samples",UPN2_061,2,25464519,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val665Gly/c.1994T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17438,468,18002,"0,0259971114",0,0,0,0,1,0,0,0,1,NO,NO,COSM231559,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,"8,24E-006",NO,NO,"-6,76",Deleterious,1,Damaging,"27,9","15,14"
"low bq, many samples",UPN2_062,2,25464519,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val665Gly/c.1994T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),15460,489,16070,"0,0304293715",0,0,0,0,1,0,0,0,1,NO,NO,COSM231559,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,"8,24E-006",NO,NO,"-6,76",Deleterious,1,Damaging,"27,63","15,28"
"low bq, many samples",UPN2_063,2,25464519,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val665Gly/c.1994T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),16979,486,17614,"0,0275916884",0,0,0,0,1,0,0,0,1,NO,NO,COSM231559,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,"8,24E-006",NO,NO,"-6,76",Deleterious,1,Damaging,"27,9","15,61"
"low bq, many samples",UPN2_064,2,25464519,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val665Gly/c.1994T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),26565,726,27497,"0,0264028803",0,0,0,0,1,0,0,0,1,NO,NO,COSM231559,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,"8,24E-006",NO,NO,"-6,76",Deleterious,1,Damaging,"27,96","15,32"
"low bq, many samples",UPN2_065,2,25464519,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val665Gly/c.1994T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),22626,577,23359,"0,0247013999",0,0,0,0,1,0,0,0,1,NO,NO,COSM231559,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,"8,24E-006",NO,NO,"-6,76",Deleterious,1,Damaging,"28,14","14,99"
"low bq, many samples",UPN2_066,2,25464519,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val665Gly/c.1994T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),24740,639,25534,"0,0250254563",0,0,0,0,1,0,0,0,1,NO,NO,COSM231559,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,"8,24E-006",NO,NO,"-6,76",Deleterious,1,Damaging,"28,14","15,17"
"low bq, low freq, many artifacts, many samples",UPN2_067,2,25464519,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val665Gly/c.1994T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),23127,510,23777,"0,0214492997",0,0,0,0,1,0,0,0,1,NO,NO,COSM231559,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,"8,24E-006",NO,NO,"-6,76",Deleterious,1,Damaging,"28,36","14,94"
"low bq, many samples",UPN2_068,2,25464519,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val665Gly/c.1994T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17183,526,17839,"0,0294859577",0,0,0,0,1,0,0,0,1,NO,NO,COSM231559,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,"8,24E-006",NO,NO,"-6,76",Deleterious,1,Damaging,"27,65","14,52"
"low bq, many samples",UPN2_069,2,25464519,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val665Gly/c.1994T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),20802,601,21539,"0,0279028739",0,0,0,0,1,0,0,0,1,NO,NO,COSM231559,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,"8,24E-006",NO,NO,"-6,76",Deleterious,1,Damaging,"27,87","15,38"
"low bq, many samples",UPN2_070,2,25464519,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val665Gly/c.1994T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),12576,374,13029,"0,0287051961",0,0,0,0,1,0,0,0,1,NO,NO,COSM231559,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,"8,24E-006",NO,NO,"-6,76",Deleterious,1,Damaging,"27,77","15,21"
"low bq, many samples",UPN2_071,2,25464519,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val665Gly/c.1994T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),10951,291,11352,"0,0256342495",0,0,0,0,1,0,0,0,1,NO,NO,COSM231559,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,"8,24E-006",NO,NO,"-6,76",Deleterious,1,Damaging,"27,96","14,78"
"low bq, many samples",UPN2_072,2,25464519,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val665Gly/c.1994T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),15247,444,15800,"0,0281012658",0,0,0,0,1,0,0,0,1,NO,NO,COSM231559,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,"8,24E-006",NO,NO,"-6,76",Deleterious,1,Damaging,"27,96","14,79"
"low bq, many samples",UPN2_073,2,25464519,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val665Gly/c.1994T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),15065,391,15563,"0,0251236908",0,0,0,0,1,0,0,0,1,NO,NO,COSM231559,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,"8,24E-006",NO,NO,"-6,76",Deleterious,1,Damaging,"28,06","14,97"
"low bq, many samples",UPN2_074,2,25464519,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val665Gly/c.1994T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),12467,289,12825,"0,0225341131",0,0,0,0,1,0,0,0,1,NO,NO,COSM231559,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,"8,24E-006",NO,NO,"-6,76",Deleterious,1,Damaging,"28,09","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25464519,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val665Gly/c.1994T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),19847,425,20401,"0,0208323121",0,0,0,0,1,0,0,0,1,NO,NO,COSM231559,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,"8,24E-006",NO,NO,"-6,76",Deleterious,1,Damaging,"28,37","15,29"
"low bq, many samples",UPN2_076,2,25464519,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val665Gly/c.1994T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),16069,459,16630,"0,0276007216",0,0,0,0,1,0,0,0,1,NO,NO,COSM231559,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,"8,24E-006",NO,NO,"-6,76",Deleterious,1,Damaging,"27,56","14,91"
"low bq, many samples",UPN2_077,2,25464519,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val665Gly/c.1994T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),20975,600,21670,"0,027688048",0,0,0,0,1,0,0,0,1,NO,NO,COSM231559,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,"8,24E-006",NO,NO,"-6,76",Deleterious,1,Damaging,"27,81","14,82"
"low bq, many samples",UPN2_078,2,25464519,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val665Gly/c.1994T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17202,530,17877,"0,0296470325",0,0,0,0,1,0,0,0,1,NO,NO,COSM231559,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,"8,24E-006",NO,NO,"-6,76",Deleterious,1,Damaging,"27,52","14,68"
"low bq, many samples",UPN2_079,2,25464519,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val665Gly/c.1994T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),11661,287,12036,"0,0238451313",0,0,0,0,1,0,0,0,1,NO,NO,COSM231559,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,"8,24E-006",NO,NO,"-6,76",Deleterious,1,Damaging,"28,07","14,78"
"low bq, many samples",UPN2_080,2,25464519,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val665Gly/c.1994T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17181,457,17746,"0,0257522822",0,0,0,0,1,0,0,0,1,NO,NO,COSM231559,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,"8,24E-006",NO,NO,"-6,76",Deleterious,1,Damaging,"27,96","14,76"
"low bq, many samples",UPN2_081,2,25464519,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val665Gly/c.1994T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),29062,765,29981,"0,0255161602",0,0,0,0,1,0,0,0,1,NO,NO,COSM231559,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,"8,24E-006",NO,NO,"-6,76",Deleterious,1,Damaging,"28,13","15,02"
"low bq, many samples",UPN2_082,2,25464519,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val665Gly/c.1994T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),23090,587,23843,"0,0246193851",0,0,0,0,1,0,0,0,1,NO,NO,COSM231559,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,"8,24E-006",NO,NO,"-6,76",Deleterious,1,Damaging,"28,29","15,52"
"low bq, many samples",UPN2_083,2,25464519,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val665Gly/c.1994T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),19991,590,20713,"0,0284845266",0,0,0,0,1,0,0,0,1,NO,NO,COSM231559,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,"8,24E-006",NO,NO,"-6,76",Deleterious,1,Damaging,"27,59","15,15"
"low bq, many samples",UPN2_084,2,25464519,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val665Gly/c.1994T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),20797,651,21595,"0,0301458671",0,0,0,0,1,0,0,0,1,NO,NO,COSM231559,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,"8,24E-006",NO,NO,"-6,76",Deleterious,1,Damaging,"27,67","14,87"
"low bq, many samples",UPN2_085,2,25464519,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val665Gly/c.1994T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17419,427,17930,"0,0238148355",0,0,0,0,1,0,0,0,1,NO,NO,COSM231559,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,"8,24E-006",NO,NO,"-6,76",Deleterious,1,Damaging,"27,94","15,02"
"low bq, many samples",UPN2_086,2,25464519,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val665Gly/c.1994T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),11989,371,12454,"0,0297896258",0,0,0,0,1,0,0,0,1,NO,NO,COSM231559,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,"8,24E-006",NO,NO,"-6,76",Deleterious,1,Damaging,"27,79","14,69"
"low bq, many samples",UPN2_087,2,25464519,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val665Gly/c.1994T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),24408,664,25234,"0,0263137037",0,0,0,0,1,0,0,0,1,NO,NO,COSM231559,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,"8,24E-006",NO,NO,"-6,76",Deleterious,1,Damaging,"27,91","15,47"
low bq,UPN2_088,2,25464519,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val665Gly/c.1994T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),18853,456,19414,"0,0234882044",0,0,0,0,1,0,0,0,1,NO,NO,COSM231559,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,"8,24E-006",NO,NO,"-6,76",Deleterious,1,Damaging,"28,36","15,01"
"inspected, many artifacts",UPN2_019,2,25464537,C,T,missense_variant(MODERATE|MISSENSE|cGc/cAc|p.Arg659His/c.1976G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|T),9687,145,9843,"0,0147312811",0,0,0,0,1,1,0,1,3,NO,NO,COSM1019235,"central_nervous_system, endometrium","1, 1",NO,NO,NO,"1,65E-005",NO,NO,"-3,55",Deleterious,"0,038",Damaging,"33,69","31,26"
"not in 2nd Illumina, low freq, no database",UPN2_006,2,25464537,C,T,missense_variant(MODERATE|MISSENSE|cGc/cAc|p.Arg659His/c.1976G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|T),4719,68,4791,"0,0141932791",0,0,0,0,1,0,0,1,2,NO,NO,COSM1019235,"central_nervous_system, endometrium","1, 1",NO,NO,NO,"1,65E-005",NO,NO,"-3,55",Deleterious,"0,038",Damaging,"34,54","29,04"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,25464540,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp658Ala/c.1973A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),30377,486,31053,"0,0156506618",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,85",Deleterious,11,Damaging,"27,51","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25464540,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp658Ala/c.1973A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),17463,285,17847,"0,0159690704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,85",Deleterious,11,Damaging,"27,32","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25464540,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp658Ala/c.1973A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),17602,323,18000,"0,0179444444",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,85",Deleterious,11,Damaging,"27,24","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25464540,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp658Ala/c.1973A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),15692,284,16070,"0,017672682",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,85",Deleterious,11,Damaging,"27,01","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25464540,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp658Ala/c.1973A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),17236,283,17621,"0,0160603825",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,85",Deleterious,11,Damaging,"27,44","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25464540,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp658Ala/c.1973A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),26916,437,27493,"0,0158949551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,85",Deleterious,11,Damaging,"27,47","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,25464540,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp658Ala/c.1973A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),22842,367,23364,"0,0157079267",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,85",Deleterious,11,Damaging,"27,63","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_066,2,25464540,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp658Ala/c.1973A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),24997,419,25540,"0,0164056382",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,85",Deleterious,11,Damaging,"27,59","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_067,2,25464540,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp658Ala/c.1973A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),23348,308,23787,"0,012948249",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,85",Deleterious,11,Damaging,"27,65","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25464540,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp658Ala/c.1973A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),17450,308,17834,"0,0172703824",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,85",Deleterious,11,Damaging,"27,19","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25464540,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp658Ala/c.1973A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),21087,353,21544,"0,0163850724",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,85",Deleterious,11,Damaging,"27,27","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,25464540,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp658Ala/c.1973A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),12747,222,13030,"0,0170376055",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,85",Deleterious,11,Damaging,"27,03","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25464540,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp658Ala/c.1973A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),11124,189,11362,"0,0166343954",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,85",Deleterious,11,Damaging,"27,49","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25464540,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp658Ala/c.1973A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),15470,245,15807,"0,0154994623",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,85",Deleterious,11,Damaging,"27,51","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25464540,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp658Ala/c.1973A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),15257,253,15564,"0,0162554613",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,85",Deleterious,11,Damaging,"27,51","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,25464540,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp658Ala/c.1973A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),12545,219,12830,"0,0170693687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,85",Deleterious,11,Damaging,"27,46","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25464540,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp658Ala/c.1973A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),19948,311,20408,"0,0152391219",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,85",Deleterious,11,Damaging,"27,64","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25464540,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp658Ala/c.1973A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),16257,264,16629,"0,0158758795",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,85",Deleterious,11,Damaging,"27,15","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25464540,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp658Ala/c.1973A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),21183,373,21667,"0,0172151198",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,85",Deleterious,11,Damaging,"27,24","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25464540,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp658Ala/c.1973A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),17441,319,17877,"0,0178441573",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,85",Deleterious,11,Damaging,"27,09","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25464540,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp658Ala/c.1973A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),11785,186,12040,"0,015448505",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,85",Deleterious,11,Damaging,"27,48","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25464540,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp658Ala/c.1973A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),17406,263,17754,"0,0148135631",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,85",Deleterious,11,Damaging,"27,4","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25464540,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp658Ala/c.1973A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),29360,465,29988,"0,0155062025",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,85",Deleterious,11,Damaging,"27,67","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25464540,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp658Ala/c.1973A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),23314,350,23835,"0,0146842878",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,85",Deleterious,11,Damaging,"27,44","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25464540,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp658Ala/c.1973A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),20263,356,20710,"0,0171897634",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,85",Deleterious,11,Damaging,"27,11","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25464540,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp658Ala/c.1973A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),21171,322,21598,"0,0149087879",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,85",Deleterious,11,Damaging,"27,22",15
"low bq, low freq, many artifacts, many samples",UPN2_085,2,25464540,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp658Ala/c.1973A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),17579,249,17930,"0,0138873397",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,85",Deleterious,11,Damaging,"27,39","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_086,2,25464540,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp658Ala/c.1973A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),12152,237,12460,"0,0190208668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,85",Deleterious,11,Damaging,"27,39","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_087,2,25464540,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp658Ala/c.1973A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),24677,420,25235,"0,0166435506",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,85",Deleterious,11,Damaging,"27,47","14,89"
"low bq, low freq, many artifacts",UPN2_088,2,25464540,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp658Ala/c.1973A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),19000,284,19417,"0,0146263583",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,85",Deleterious,11,Damaging,"27,72","14,71"
"low bq, many samples",UPN2_059,2,25464543,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val657Gly/c.1970T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),30069,789,31017,"0,0254376632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,56",Deleterious,0,Damaging,"29,38","15,17"
"low bq, many samples",UPN2_060,2,25464543,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val657Gly/c.1970T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17282,443,17832,"0,0248429789",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,56",Deleterious,0,Damaging,"29,41","14,9"
"low bq, many samples",UPN2_061,2,25464543,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val657Gly/c.1970T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17425,460,17972,"0,0255953706",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,56",Deleterious,0,Damaging,"29,09","15,15"
"low bq, many samples",UPN2_062,2,25464543,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val657Gly/c.1970T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),15447,509,16050,"0,0317133956",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,56",Deleterious,0,Damaging,"29,09","15,02"
"low bq, many samples",UPN2_063,2,25464543,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val657Gly/c.1970T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),16984,473,17596,"0,0268811093",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,56",Deleterious,0,Damaging,"29,19","15,1"
"low bq, many samples",UPN2_064,2,25464543,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val657Gly/c.1970T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),26599,732,27465,"0,0266521027",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,56",Deleterious,0,Damaging,"29,25","15,03"
"low bq, many samples",UPN2_065,2,25464543,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val657Gly/c.1970T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),22579,629,23343,"0,0269459795",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,56",Deleterious,0,Damaging,"29,42","15,41"
"low bq, many samples",UPN2_066,2,25464543,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val657Gly/c.1970T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),24766,613,25513,"0,0240269666",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,56",Deleterious,0,Damaging,"29,41","15,13"
"low bq, many samples",UPN2_067,2,25464543,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val657Gly/c.1970T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),23007,616,23773,"0,0259117486",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,56",Deleterious,0,Damaging,"29,67","15,06"
"low bq, many samples",UPN2_068,2,25464543,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val657Gly/c.1970T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17195,538,17817,"0,0301958803",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,56",Deleterious,0,Damaging,"29,13","15,13"
"low bq, many samples",UPN2_069,2,25464543,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val657Gly/c.1970T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),20814,613,21519,"0,0284864538",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,56",Deleterious,0,Damaging,"29,19","15,16"
"low bq, many samples",UPN2_070,2,25464543,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val657Gly/c.1970T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),12531,403,13008,"0,0309809348",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,56",Deleterious,0,Damaging,"29,08","15,34"
"low bq, many samples",UPN2_071,2,25464543,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val657Gly/c.1970T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),10979,297,11340,"0,0261904762",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,56",Deleterious,0,Damaging,"29,19","15,12"
"low bq, many samples",UPN2_072,2,25464543,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val657Gly/c.1970T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),15288,422,15785,"0,0267342414",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,56",Deleterious,0,Damaging,"29,33","14,96"
"low bq, many samples",UPN2_073,2,25464543,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val657Gly/c.1970T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),15025,411,15536,"0,0264546859",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,56",Deleterious,0,Damaging,"29,37","15,15"
"low bq, many samples",UPN2_074,2,25464543,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val657Gly/c.1970T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),12443,313,12808,"0,0244378513",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,56",Deleterious,0,Damaging,"29,29","14,74"
"low bq, many samples",UPN2_075,2,25464543,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val657Gly/c.1970T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),19811,498,20386,"0,0244285294",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,56",Deleterious,0,Damaging,"29,53","15,2"
"low bq, many samples",UPN2_076,2,25464543,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val657Gly/c.1970T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),16024,500,16615,"0,0300932892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,56",Deleterious,0,Damaging,"29,08","14,9"
"low bq, many samples",UPN2_077,2,25464543,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val657Gly/c.1970T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),20936,586,21634,"0,0270869927",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,56",Deleterious,0,Damaging,"29,2","15,33"
"low bq, many samples",UPN2_078,2,25464543,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val657Gly/c.1970T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17230,536,17849,"0,0300296935",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,56",Deleterious,0,Damaging,"29,03","14,96"
"low bq, many samples",UPN2_079,2,25464543,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val657Gly/c.1970T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),11696,276,12026,"0,0229502744",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,56",Deleterious,0,Damaging,"29,2","15,57"
"low bq, many samples",UPN2_080,2,25464543,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val657Gly/c.1970T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17190,455,17737,"0,0256525906",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,56",Deleterious,0,Damaging,"29,22","14,95"
"low bq, many samples",UPN2_081,2,25464543,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val657Gly/c.1970T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),28970,777,29952,"0,0259415064",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,56",Deleterious,0,Damaging,"29,5","15,02"
"low bq, many samples",UPN2_082,2,25464543,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val657Gly/c.1970T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),23034,597,23812,"0,0250713926",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,56",Deleterious,0,Damaging,"29,48","14,96"
"low bq, many samples",UPN2_083,2,25464543,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val657Gly/c.1970T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),19949,608,20682,"0,0293975438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,56",Deleterious,0,Damaging,"29,07","15,12"
"low bq, many samples",UPN2_084,2,25464543,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val657Gly/c.1970T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),20826,644,21578,"0,0298452127",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,56",Deleterious,0,Damaging,"29,06","15,02"
"low bq, many samples",UPN2_085,2,25464543,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val657Gly/c.1970T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),17365,478,17916,"0,0266800625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,56",Deleterious,0,Damaging,"29,25","15,23"
"low bq, many samples",UPN2_086,2,25464543,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val657Gly/c.1970T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),12062,335,12443,"0,0269227678",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,56",Deleterious,0,Damaging,"29,08","15,19"
"low bq, many samples",UPN2_087,2,25464543,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val657Gly/c.1970T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),24326,727,25214,"0,0288331879",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,56",Deleterious,0,Damaging,"29,28","15,01"
low bq,UPN2_088,2,25464543,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val657Gly/c.1970T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),18862,460,19396,"0,0237162302",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,56",Deleterious,0,Damaging,"29,44","15,45"
"not in 2nd Illumina, low freq, no database",UPN2_006,2,25464549,A,G,missense_variant(MODERATE|MISSENSE|aTt/aCt|p.Ile655Thr/c.1964T>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),2346,29,2390,"0,0121338912",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,33",Deleterious,"0,001",Damaging,"31,88","35,34"
"low bq, low freq, many artifacts, many samples",UPN2_041,2,25464555,A,T,stop_gained(HIGH|NONSENSE|tTg/tAg|p.Leu653*/c.1958T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|T),15984,192,16244,"0,0118197488",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,89","24,92"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,25464555,A,T,stop_gained(HIGH|NONSENSE|tTg/tAg|p.Leu653*/c.1958T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|T),5588,60,5675,"0,0105726872",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,91",21
"low bq, low freq, many artifacts, many samples",UPN2_045,2,25464555,A,T,stop_gained(HIGH|NONSENSE|tTg/tAg|p.Leu653*/c.1958T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|T),8205,97,8346,"0,0116223341",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,88","24,76"
"low bq, low freq, many artifacts",UPN2_054,2,25464555,A,T,stop_gained(HIGH|NONSENSE|tTg/tAg|p.Leu653*/c.1958T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|T),5789,61,5881,"0,0103723856",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,39","21,69"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,2,25464558,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp652Ala/c.1955A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),7833,82,7966,"0,0102937484",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,37",Deleterious,33,Damaging,"25,75","14,33"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_070,2,25464558,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp652Ala/c.1955A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|G),6369,69,6460,"0,0106811146",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,37",Deleterious,33,Damaging,"25,98","14,32"
"inspected, many artifacts",UPN2_093,2,25464561,T,C,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys651Arg/c.1952A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|C),2648,32,2680,"0,0119402985",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,"0,235",Tolerated,"34,61","35,59"
"low bq, low freq, many artifacts, many samples",UPN2_041,2,25464567,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val649Glu/c.1946T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|17|T),15973,172,16248,"0,0105859183",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,56",Deleterious,2,Damaging,"33,46","22,56"
"inspected, bad alignment, many artifacts",UPN2_044,2,25466769,G,T,missense_variant(MODERATE|MISSENSE|aCa/aAa|p.Thr645Lys/c.1934C>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|T),2223,31,2257,"0,0137350465",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,93",Deleterious,"0,055",Tolerated,"34,98","34,19"
"inspected, many artifacts",UPN2_048,2,25466785,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe640Leu/c.1918T>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|G),14150,148,14316,"0,0103380833",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,98",Deleterious,"0,006",Damaging,"35,48","35,23"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25466791,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser638Ala/c.1912T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),3047,47,3113,"0,0150979762",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,7",Deleterious,21,Damaging,"30,17","15,68"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25466791,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser638Ala/c.1912T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),6238,76,6331,"0,0120044227",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,7",Deleterious,21,Damaging,"30,59","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25466791,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser638Ala/c.1912T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),4007,51,4070,"0,0125307125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,7",Deleterious,21,Damaging,"30,24","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25466791,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser638Ala/c.1912T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),4885,53,4949,"0,0107092342",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,7",Deleterious,21,Damaging,"30,73","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,25466791,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser638Ala/c.1912T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),3189,36,3244,"0,0110974106",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,7",Deleterious,21,Damaging,"30,87","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25466791,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser638Ala/c.1912T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),4304,50,4373,"0,0114337983",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,7",Deleterious,21,Damaging,"30,6","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,25466791,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser638Ala/c.1912T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),3131,33,3179,"0,0103806228",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,7",Deleterious,21,Damaging,"30,91","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25466791,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser638Ala/c.1912T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),5297,63,5388,"0,0116926503",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,7",Deleterious,21,Damaging,"31,01","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25466791,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser638Ala/c.1912T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),4908,56,4983,"0,0112382099",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,7",Deleterious,21,Damaging,"30,39","15,71"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25466791,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser638Ala/c.1912T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),3029,34,3078,"0,0110461339",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,7",Deleterious,21,Damaging,"30,89","15,79"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25466791,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser638Ala/c.1912T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),5007,52,5074,"0,0102483248",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,7",Deleterious,21,Damaging,"30,38","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25466791,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser638Ala/c.1912T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),5160,56,5239,"0,0106890628",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,7",Deleterious,21,Damaging,"30,54","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,25466791,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser638Ala/c.1912T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),4422,46,4489,"0,0102472711",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,7",Deleterious,21,Damaging,"30,34","15,02"
"low bq, low freq, many artifacts",UPN2_086,2,25466791,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser638Ala/c.1912T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),3052,40,3105,"0,0128824477",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,7",Deleterious,21,Damaging,"30,29","15,07"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_059,2,25466796,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val636Gly/c.1907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),6382,88,6497,"0,0135447129",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,99",Deleterious,0,Damaging,"25,34","14,67"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_060,2,25466796,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val636Gly/c.1907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),4767,60,4850,"0,012371134",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,99",Deleterious,0,Damaging,"25,05","14,58"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,2,25466796,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val636Gly/c.1907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),3961,66,4049,"0,0163003211",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,99",Deleterious,0,Damaging,"24,79","14,48"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,2,25466796,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val636Gly/c.1907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),3039,60,3113,"0,0192740122",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,99",Deleterious,0,Damaging,"24,19","14,12"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,2,25466796,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val636Gly/c.1907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),3901,57,3969,"0,0143613001",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,99",Deleterious,0,Damaging,"25,21","14,86"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,2,25466796,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val636Gly/c.1907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),6202,103,6331,"0,0162691518",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,99",Deleterious,0,Damaging,"25,04","14,14"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_065,2,25466796,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val636Gly/c.1907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),5156,75,5260,"0,0142585551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,99",Deleterious,0,Damaging,"25,39","14,27"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_066,2,25466796,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val636Gly/c.1907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),4769,69,4857,"0,0142063002",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,99",Deleterious,0,Damaging,"25,19","14,97"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_067,2,25466796,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val636Gly/c.1907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),4581,64,4656,"0,0137457045",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,99",Deleterious,0,Damaging,"25,75","15,62"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_068,2,25466796,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val636Gly/c.1907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),3973,74,4070,"0,0181818182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,99",Deleterious,0,Damaging,"24,61","14,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_069,2,25466796,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val636Gly/c.1907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),4850,78,4949,"0,0157607597",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,99",Deleterious,0,Damaging,"24,68","15,01"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_070,2,25466796,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val636Gly/c.1907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),3185,50,3244,"0,0154130703",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,99",Deleterious,0,Damaging,"24,61","14,94"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,2,25466796,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val636Gly/c.1907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),3078,38,3130,"0,0121405751",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,99",Deleterious,0,Damaging,"24,6","14,18"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,2,25466796,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val636Gly/c.1907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),4284,74,4373,"0,0169220215",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,99",Deleterious,0,Damaging,"24,79","15,15"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,2,25466796,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val636Gly/c.1907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),4158,60,4230,"0,0141843972",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,99",Deleterious,0,Damaging,"25,2","14,65"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,2,25466796,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val636Gly/c.1907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),3128,37,3179,"0,0116388802",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,99",Deleterious,0,Damaging,"25,17","16,11"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_075,2,25466796,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val636Gly/c.1907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),5292,68,5386,"0,0126253249",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,99",Deleterious,0,Damaging,"25,24","14,5"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,2,25466796,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val636Gly/c.1907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),4112,80,4221,"0,0189528548",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,99",Deleterious,0,Damaging,"24,77","14,7"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,2,25466796,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val636Gly/c.1907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),4910,53,4983,"0,010636163",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,99",Deleterious,0,Damaging,"24,69","15,3"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,2,25466796,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val636Gly/c.1907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),4268,59,4349,"0,0135663371",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,99",Deleterious,0,Damaging,"24,58",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_079,2,25466796,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val636Gly/c.1907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),3019,37,3077,"0,0120246994",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,99",Deleterious,0,Damaging,"24,98","14,38"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,2,25466796,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val636Gly/c.1907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),4159,69,4250,"0,0162352941",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,99",Deleterious,0,Damaging,"25,02","15,33"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_081,2,25466796,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val636Gly/c.1907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),7157,114,7297,"0,0156228587",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,99",Deleterious,0,Damaging,"25,09","14,36"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_082,2,25466796,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val636Gly/c.1907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),5250,62,5329,"0,011634453",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,99",Deleterious,0,Damaging,"25,48","14,4"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,2,25466796,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val636Gly/c.1907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),4977,81,5074,"0,0159637367",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,99",Deleterious,0,Damaging,"24,7","14,42"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,2,25466796,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val636Gly/c.1907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),5131,67,5239,"0,0127887001",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,99",Deleterious,0,Damaging,"24,97","14,31"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_085,2,25466796,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val636Gly/c.1907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),4415,59,4489,"0,013143239",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,99",Deleterious,0,Damaging,"24,83","15,02"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,2,25466796,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val636Gly/c.1907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),3033,59,3105,"0,0190016103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,99",Deleterious,0,Damaging,"25,04","14,64"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_087,2,25466796,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val636Gly/c.1907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),6634,105,6767,"0,015516477",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,99",Deleterious,0,Damaging,"24,77","14,2"
"low bq, bad alignment, low freq, many artifacts",UPN2_088,2,25466796,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val636Gly/c.1907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),4361,64,4438,"0,0144209103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,99",Deleterious,0,Damaging,"25,5","14,75"
low bq,UPN2_007,2,25466797,C,A,missense_variant(MODERATE|MISSENSE|Gtg/Ttg|p.Val636Leu/c.1906G>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|A),9402,251,9670,"0,0259565667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-3,Deleterious,17,Damaging,"35,16","25,64"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_048,2,25466838,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val622Gly/c.1865T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),13926,159,14186,"0,0112082335",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,6,Damaging,"22,56","25,43"
"low bq, bad alignment, many samples",UPN2_059,2,25466838,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val622Gly/c.1865T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),6161,290,6492,"0,0446703635",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,6,Damaging,"20,39","15,28"
"low bq, bad alignment, many samples",UPN2_060,2,25466838,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val622Gly/c.1865T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),4629,178,4840,"0,0367768595",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,6,Damaging,"20,47","14,66"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_091,2,25466838,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val622Gly/c.1865T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),4010,42,4071,"0,0103168755",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,6,Damaging,"23,26","17,14"
"low bq, bad alignment, many samples",UPN2_061,2,25466838,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val622Gly/c.1865T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),3818,181,4045,"0,0447466007",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,6,Damaging,"19,73","15,77"
"low bq, bad alignment, many samples",UPN2_062,2,25466838,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val622Gly/c.1865T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),2936,149,3111,"0,0478945677",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,6,Damaging,"19,82","15,15"
"low bq, bad alignment, many samples",UPN2_063,2,25466838,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val622Gly/c.1865T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),3789,156,3966,"0,0393343419",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,6,Damaging,"20,23","16,04"
"low bq, bad alignment, many samples",UPN2_064,2,25466838,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val622Gly/c.1865T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),6001,273,6323,"0,0431757077",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,6,Damaging,"19,92","14,99"
"low bq, bad alignment, many samples",UPN2_065,2,25466838,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val622Gly/c.1865T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),5014,210,5253,"0,0399771559",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,6,Damaging,"20,46","15,31"
"low bq, bad alignment, many samples",UPN2_066,2,25466838,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val622Gly/c.1865T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),4638,182,4852,"0,037510305",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,6,Damaging,"20,06","15,65"
"low bq, bad alignment, many samples",UPN2_067,2,25466838,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val622Gly/c.1865T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),4448,176,4650,"0,0378494624",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,6,Damaging,"20,7","14,81"
"low bq, bad alignment, many samples",UPN2_068,2,25466838,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val622Gly/c.1865T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),3837,190,4065,"0,0467404674",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,6,Damaging,"19,76","15,2"
"low bq, bad alignment, many samples",UPN2_069,2,25466838,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val622Gly/c.1865T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),4713,207,4942,"0,0418858762",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,6,Damaging,"20,53","14,96"
"low bq, bad alignment, many samples",UPN2_070,2,25466838,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val622Gly/c.1865T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),3070,141,3239,"0,0435319543",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,6,Damaging,"20,21","15,03"
"low bq, bad alignment, many samples",UPN2_071,2,25466838,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val622Gly/c.1865T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),2977,128,3126,"0,040946897",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,6,Damaging,"19,86","15,75"
"low bq, bad alignment, many samples",UPN2_072,2,25466838,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val622Gly/c.1865T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),4136,200,4371,"0,0457561199",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,6,Damaging,"19,7","14,77"
"low bq, bad alignment, many samples",UPN2_073,2,25466838,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val622Gly/c.1865T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),4027,167,4225,"0,0395266272",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,6,Damaging,"20,44","15,13"
"low bq, bad alignment, many samples",UPN2_074,2,25466838,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val622Gly/c.1865T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),3026,121,3175,"0,0381102362",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,6,Damaging,"20,59","15,63"
"low bq, bad alignment, many samples",UPN2_075,2,25466838,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val622Gly/c.1865T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),5116,223,5377,"0,0414729403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,6,Damaging,"20,28","15,07"
"low bq, bad alignment, many samples",UPN2_076,2,25466838,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val622Gly/c.1865T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),3984,206,4220,"0,0488151659",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,6,Damaging,"19,7","14,97"
"low bq, bad alignment, many samples",UPN2_077,2,25466838,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val622Gly/c.1865T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),4699,244,4976,"0,0490353698",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,6,Damaging,"19,94","15,56"
"low bq, bad alignment, many samples",UPN2_078,2,25466838,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val622Gly/c.1865T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),4141,169,4344,"0,0389042357",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,6,Damaging,"20,04","15,35"
"low bq, bad alignment, many samples",UPN2_079,2,25466838,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val622Gly/c.1865T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),2919,130,3072,"0,0423177083",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,6,Damaging,"20,22","14,39"
"low bq, bad alignment, many samples",UPN2_080,2,25466838,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val622Gly/c.1865T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),4039,178,4244,"0,0419415646",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,6,Damaging,"19,72","15,44"
"low bq, bad alignment, many samples",UPN2_081,2,25466838,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val622Gly/c.1865T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),6887,350,7289,"0,0480175607",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,6,Damaging,"20,02","15,14"
"low bq, bad alignment, many samples",UPN2_082,2,25466838,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val622Gly/c.1865T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),5106,181,5324,"0,0339969947",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,6,Damaging,"20,93","15,08"
"low bq, bad alignment, many samples",UPN2_083,2,25466838,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val622Gly/c.1865T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),4833,204,5068,"0,0402525651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,6,Damaging,"19,92","14,93"
"low bq, bad alignment, many samples",UPN2_084,2,25466838,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val622Gly/c.1865T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),4983,227,5233,"0,0433785591",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,6,Damaging,"20,11","15,06"
"low bq, bad alignment, many samples",UPN2_085,2,25466838,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val622Gly/c.1865T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),4253,194,4479,"0,0433132396",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,6,Damaging,"19,7","14,77"
"low bq, bad alignment, many samples",UPN2_086,2,25466838,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val622Gly/c.1865T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),2927,146,3100,"0,0470967742",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,6,Damaging,"19,91","14,77"
"low bq, bad alignment, many samples",UPN2_087,2,25466838,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val622Gly/c.1865T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),6382,332,6749,"0,049192473",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,6,Damaging,"19,8","15,28"
"low bq, bad alignment, many samples",UPN2_088,2,25466838,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val622Gly/c.1865T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),4239,173,4435,"0,0390078918",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,6,Damaging,"20,07","16,21"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_095,2,25466838,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val622Gly/c.1865T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),4171,45,4233,"0,0106307583",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,6,Damaging,"22,9","20,02"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_097,2,25466838,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val622Gly/c.1865T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),5013,51,5084,"0,0100314713",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,6,Damaging,"23,35","19,16"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_098,2,25466838,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val622Gly/c.1865T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),3948,45,4005,"0,0112359551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,6,Damaging,"22,79","18,87"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_102,2,25466838,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val622Gly/c.1865T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),3788,47,3853,"0,012198287",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,6,Damaging,"23,43","17,96"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_103,2,25466838,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val622Gly/c.1865T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),3135,35,3185,"0,010989011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,6,Damaging,"22,94","18,91"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_106,2,25466838,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val622Gly/c.1865T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),6333,65,6422,"0,0101214575",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,6,Damaging,"23,13","18,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_109,2,25466838,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val622Gly/c.1865T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),5339,55,5412,"0,0101626016",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,6,Damaging,"23,11","19,56"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_110,2,25466838,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val622Gly/c.1865T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),5431,63,5509,"0,0114358323",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,6,Damaging,"23,83","19,87"
"low bq, bad alignment, low freq, many artifacts",UPN2_111,2,25466838,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val622Gly/c.1865T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|C),4539,53,4604,"0,0115117289",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,6,Damaging,"23,08","16,42"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25466841,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys621Thr/c.1862A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|G),3965,48,4045,"0,0118665019",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,59",Deleterious,22,Damaging,"28,84","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25466841,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys621Thr/c.1862A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|G),3050,43,3111,"0,0138219222",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,59",Deleterious,22,Damaging,"28,49","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25466841,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys621Thr/c.1862A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|G),3895,47,3966,"0,0118507312",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,59",Deleterious,22,Damaging,"29,57","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25466841,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys621Thr/c.1862A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|G),6195,81,6323,"0,0128103748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,59",Deleterious,22,Damaging,"28,82","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,25466841,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys621Thr/c.1862A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|G),5155,56,5253,"0,0106605749",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,59",Deleterious,22,Damaging,"29,47","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_066,2,25466841,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys621Thr/c.1862A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|G),4772,50,4852,"0,0103050289",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,59",Deleterious,22,Damaging,"29,63","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25466841,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys621Thr/c.1862A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|G),3973,66,4065,"0,0162361624",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,59",Deleterious,22,Damaging,"28,57","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25466841,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys621Thr/c.1862A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|G),4837,63,4940,"0,0127530364",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,59",Deleterious,22,Damaging,"29,65","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,25466841,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys621Thr/c.1862A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|G),3174,43,3239,"0,0132757024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,59",Deleterious,22,Damaging,"29,02","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25466841,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys621Thr/c.1862A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|G),3059,38,3125,"0,01216",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,59",Deleterious,22,Damaging,"28,59","15,34"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25466841,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys621Thr/c.1862A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|G),4267,73,4369,"0,016708629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,59",Deleterious,22,Damaging,"28,81","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25466841,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys621Thr/c.1862A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|G),4137,52,4225,"0,0123076923",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,59",Deleterious,22,Damaging,"29,32","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25466841,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys621Thr/c.1862A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|G),4127,55,4220,"0,0130331754",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,59",Deleterious,22,Damaging,"28,59","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25466841,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys621Thr/c.1862A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|G),4861,71,4976,"0,0142684887",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,59",Deleterious,22,Damaging,"28,59","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25466841,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys621Thr/c.1862A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|G),3009,43,3072,"0,0139973958",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,59",Deleterious,22,Damaging,"29,34",14
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25466841,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys621Thr/c.1862A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|G),4163,47,4244,"0,0110744581",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,59",Deleterious,22,Damaging,"28,98","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25466841,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys621Thr/c.1862A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|G),7134,93,7289,"0,0127589518",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,59",Deleterious,22,Damaging,"28,94","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25466841,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys621Thr/c.1862A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|G),4967,51,5068,"0,0100631413",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,59",Deleterious,22,Damaging,"28,9","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25466841,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys621Thr/c.1862A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|G),5108,75,5233,"0,0143321231",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,59",Deleterious,22,Damaging,"29,26","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,25466841,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys621Thr/c.1862A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|G),4394,51,4479,"0,0113864702",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,59",Deleterious,22,Damaging,"28,83","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_086,2,25466841,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys621Thr/c.1862A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|G),3023,56,3100,"0,0180645161",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,59",Deleterious,22,Damaging,"28,63","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_087,2,25466841,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys621Thr/c.1862A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|G),6617,83,6749,"0,0122981182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,59",Deleterious,22,Damaging,"28,83","14,69"
"low bq, low freq, many artifacts",UPN2_088,2,25466841,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys621Thr/c.1862A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|G),4351,61,4435,"0,0137542277",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,59",Deleterious,22,Damaging,"29,16","14,95"
"low bq, low freq, many artifacts",UPN2_069,2,25466842,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys621Gln/c.1861A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|16|G),4855,51,4940,"0,0103238866",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,41,Damaging,"30,43","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_001,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),3440,61,3514,"0,0173591349",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,33,"15,33"
"low bq, low freq, many artifacts, many samples",UPN2_014,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),6803,76,6912,"0,0109953704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"33,53","16,63"
"low bq, low freq, many artifacts, many samples",UPN2_015,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),9236,143,9422,"0,0151772447",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"33,52","16,99"
"low bq, low freq, many artifacts, many samples",UPN2_016,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),4421,54,4495,"0,0120133482",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"33,46","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_017,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),3126,38,3182,"0,0119421747",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"33,38","16,5"
"low bq, low freq, many artifacts, many samples",UPN2_018,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),4819,67,4902,"0,0136678907",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"33,35","15,73"
"low bq, low freq, many artifacts, many samples",UPN2_019,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),5003,57,5080,"0,0112204724",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"33,53","15,84"
"low bq, low freq, many artifacts, many samples",UPN2_002,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),4550,53,4618,"0,0114768298",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"32,9","16,34"
"low bq, low freq, many artifacts, many samples",UPN2_022,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),5844,65,5923,"0,0109741685",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"33,42","16,57"
"low bq, low freq, many artifacts, many samples",UPN2_023,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),7072,72,7174,"0,010036242",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"33,53","17,79"
"low bq, low freq, many artifacts, many samples",UPN2_041,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),17050,337,17452,"0,0193101077",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"32,4","16,27"
"low bq, low freq, many artifacts, many samples",UPN2_024,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),3541,44,3597,"0,0122324159",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"33,52","16,39"
"low bq, low freq, many artifacts, many samples",UPN2_025,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),8661,104,8799,"0,0118195249",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"33,45","16,41"
"low bq, low freq, many artifacts, many samples",UPN2_026,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),8477,92,8589,"0,010711375",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"33,46","15,64"
"low bq, low freq, many artifacts, many samples",UPN2_027,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),8475,116,8615,"0,0134648868",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"33,57","15,97"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),11975,259,12298,"0,021060335",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"32,4","16,24"
"low bq, low freq, many artifacts, many samples",UPN2_028,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),5927,72,6015,"0,0119700748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"33,56","15,78"
"low bq, many samples",UPN2_043,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),7786,190,8008,"0,0237262737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"32,38","16,56"
"low bq, many samples",UPN2_044,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),2525,58,2587,"0,0224197913",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"32,35","16,88"
"low bq, low freq, many artifacts, many samples",UPN2_029,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),7785,87,7904,"0,011007085",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"33,5","16,68"
"low bq, low freq, many artifacts, many samples",UPN2_030,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),7586,96,7709,"0,012452977",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"33,46","15,8"
"low bq, low freq, many artifacts, many samples",UPN2_031,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),4787,54,4853,"0,0111271379",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"33,45","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_005,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),1570,22,1598,"0,013767209",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"33,06",15
"low bq, low freq, many artifacts, many samples",UPN2_045,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10813,215,11070,"0,0194218609",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"32,46","16,76"
"low bq, low freq, many artifacts, many samples",UPN2_032,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),2818,49,2876,"0,0170375522",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"33,42","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),9654,217,9919,"0,0218772054",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"32,4","16,28"
"low bq, low freq, many artifacts, many samples",UPN2_033,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),5533,79,5636,"0,0140170334",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"33,39","16,97"
"low bq, low freq, many artifacts, many samples",UPN2_034,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),2092,30,2126,"0,0141110066",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"33,42","16,03"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),16266,326,16659,"0,0195690017",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"32,47","16,13"
"low bq, low freq, many artifacts, many samples",UPN2_048,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),15714,344,16112,"0,0213505462",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"32,49","18,8"
"low bq, low freq, many artifacts, many samples",UPN2_035,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),6840,87,6942,"0,0125324114",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"33,59","16,3"
"low bq, low freq, many artifacts, many samples",UPN2_036,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),9984,121,10151,"0,0119200079",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"33,59","16,18"
"low bq, low freq, many artifacts, many samples",UPN2_006,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),3297,57,3362,"0,0169541939",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"32,82","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),9871,196,10121,"0,0193656753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"32,35","17,16"
"low bq, many samples",UPN2_050,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),9986,235,10266,"0,0228910968",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"32,37","16,37"
"low bq, low freq, many artifacts, many samples",UPN2_037,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),12553,143,12723,"0,0112394875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"33,55","17,04"
"low bq, many samples",UPN2_051,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),7681,179,7897,"0,0226668355",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"32,23","17,09"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),8236,168,8458,"0,0198628517",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"32,3","16,76"
"low bq, low freq, many artifacts, many samples",UPN2_038,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),12110,141,12301,"0,0114624827",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"33,53","15,94"
"low bq, low freq, many artifacts, many samples",UPN2_039,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),9083,110,9220,"0,0119305857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"33,5","16,05"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10210,203,10459,"0,0194091213",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"32,4","16,38"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),6421,126,6567,"0,0191868433",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"32,2","16,12"
"low bq, low freq, many artifacts, many samples",UPN2_007,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10162,154,10359,"0,0148662998",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"33,12","15,95"
"low bq, low freq, many artifacts, many samples",UPN2_008,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),15059,243,15348,"0,0158326818",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"33,05","15,48"
"low bq, low freq, many artifacts, many samples",UPN2_009,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),12181,194,12405,"0,0156388553",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"33,1","16,03"
"low bq, low freq, many artifacts, many samples",UPN2_010,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),7286,103,7406,"0,0139076425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"32,97","16,14"
"low bq, low freq, many artifacts, many samples",UPN2_011,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),9292,159,9477,"0,0167774612",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"33,03","18,24"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10884,240,11170,"0,0214861235",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"32,45","17,23"
"low bq, low freq, many artifacts, many samples",UPN2_056,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),6875,137,7045,"0,0194464159",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"32,28","16,63"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),8755,196,8981,"0,0218238504",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"32,33","16,59"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),7807,155,8002,"0,0193701575",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"32,33","16,81"
"low bq, low freq, many artifacts, many samples",UPN2_012,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),4879,75,4972,"0,015084473",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"33,16","15,4"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),2088,24,2121,"0,0113154173",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"32,86","15,46"
"low bq, low freq, many artifacts, many samples",UPN2_013,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),2498,38,2546,"0,0149253731",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"32,92","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),2002,25,2036,"0,0122789784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"32,65",14
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),2751,33,2796,"0,0118025751",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"32,96","14,67"
"low bq, low freq, many artifacts",UPN2_083,2,25467027,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu616Asp/c.1848A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),2572,29,2619,"0,0110729286",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,192,Tolerated,"32,86","15,31"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,25467028,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu616Val/c.1847A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),9970,115,10118,"0,0113658826",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,17",Deleterious,1,Damaging,"32,8","17,42"
"low bq, low freq, many artifacts, many samples",UPN2_056,2,25467028,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu616Val/c.1847A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),6947,72,7041,"0,0102258202",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,17",Deleterious,1,Damaging,"32,86","17,74"
"low bq, low freq, many artifacts, many samples",UPN2_001,2,25467031,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln615Leu/c.1844A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),3466,37,3513,"0,0105323086",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,219,Tolerated,"33,23","15,68"
"low bq, low freq, many artifacts, many samples",UPN2_016,2,25467031,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln615Leu/c.1844A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),4435,51,4493,"0,0113509904",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,219,Tolerated,"33,64","17,22"
"low bq, low freq, many artifacts, many samples",UPN2_018,2,25467031,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln615Leu/c.1844A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),4826,57,4901,"0,0116302795",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,219,Tolerated,"33,5","18,37"
"low bq, low freq, many artifacts, many samples",UPN2_020,2,25467031,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln615Leu/c.1844A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),4797,51,4863,"0,0104873535",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,219,Tolerated,"33,79","17,8"
"low bq, low freq, many artifacts, many samples",UPN2_041,2,25467031,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln615Leu/c.1844A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),17115,259,17438,"0,0148526207",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,219,Tolerated,"32,57","16,55"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,25467031,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln615Leu/c.1844A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),12074,166,12290,"0,0135069162",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,219,Tolerated,"32,6","17,04"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,25467031,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln615Leu/c.1844A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),7826,144,8001,"0,0179977503",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,219,Tolerated,"32,7","17,27"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,25467031,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln615Leu/c.1844A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),2532,40,2583,"0,0154858691",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,219,Tolerated,"32,74","17,1"
"low bq, low freq, many artifacts, many samples",UPN2_029,2,25467031,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln615Leu/c.1844A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),7805,85,7904,"0,0107540486",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,219,Tolerated,"33,69","19,19"
"low bq, low freq, many artifacts, many samples",UPN2_030,2,25467031,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln615Leu/c.1844A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),7596,81,7704,"0,0105140187",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,219,Tolerated,"33,66","19,89"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,25467031,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln615Leu/c.1844A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10862,164,11060,"0,0148282098",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,219,Tolerated,"32,69","18,09"
"low bq, low freq, many artifacts, many samples",UPN2_032,2,25467031,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln615Leu/c.1844A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),2828,31,2874,"0,0107863605",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,219,Tolerated,"33,73","17,29"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,25467031,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln615Leu/c.1844A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),9728,145,9909,"0,0146331618",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,219,Tolerated,"32,57","15,83"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,25467031,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln615Leu/c.1844A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),16353,246,16641,"0,0147827655",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,219,Tolerated,"32,73","17,13"
"low bq, low freq, many artifacts, many samples",UPN2_048,2,25467031,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln615Leu/c.1844A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),15809,242,16097,"0,0150338572",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,219,Tolerated,"32,74","16,37"
"low bq, low freq, many artifacts, many samples",UPN2_036,2,25467031,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln615Leu/c.1844A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10001,110,10145,"0,0108427797",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,219,Tolerated,"33,73","18,06"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,25467031,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln615Leu/c.1844A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),9906,158,10112,"0,015625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,219,Tolerated,"32,59","16,46"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,25467031,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln615Leu/c.1844A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10053,161,10254,"0,0157011898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,219,Tolerated,"32,63","16,86"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,25467031,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln615Leu/c.1844A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),7746,121,7891,"0,0153339247",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,219,Tolerated,"32,56","16,31"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,25467031,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln615Leu/c.1844A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),8308,106,8449,"0,0125458634",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,219,Tolerated,"32,66","17,98"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,25467031,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln615Leu/c.1844A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10276,139,10444,"0,013309077",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,219,Tolerated,"32,66","16,77"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,25467031,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln615Leu/c.1844A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),6454,90,6564,"0,0137111517",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,219,Tolerated,"32,46","15,98"
"low bq, low freq, many artifacts, many samples",UPN2_007,2,25467031,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln615Leu/c.1844A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10172,147,10355,"0,0141960406",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,219,Tolerated,"33,24","18,29"
"low bq, low freq, many artifacts, many samples",UPN2_008,2,25467031,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln615Leu/c.1844A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),15113,189,15340,"0,0123207301",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,219,Tolerated,"33,17","16,13"
"low bq, low freq, many artifacts, many samples",UPN2_010,2,25467031,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln615Leu/c.1844A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),7309,75,7403,"0,010131028",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,219,Tolerated,"33,19","18,13"
"low bq, low freq, many artifacts, many samples",UPN2_011,2,25467031,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln615Leu/c.1844A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),9341,112,9476,"0,0118193331",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,219,Tolerated,"33,25","16,53"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,25467031,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln615Leu/c.1844A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10956,154,11165,"0,0137931034",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,219,Tolerated,"32,55","17,17"
"low bq, low freq, many artifacts, many samples",UPN2_056,2,25467031,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln615Leu/c.1844A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),6874,128,7037,"0,0181895694",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,219,Tolerated,"32,57","17,84"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,25467031,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln615Leu/c.1844A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),8802,143,8977,"0,0159295979",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,219,Tolerated,"32,58","17,57"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,25467031,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln615Leu/c.1844A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),7856,118,7996,"0,0147573787",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,219,Tolerated,"32,56","17,89"
"low bq, low freq, many artifacts, many samples",UPN2_012,2,25467031,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln615Leu/c.1844A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),4904,55,4971,"0,0110641722",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,219,Tolerated,"33,24","16,4"
"low bq, low freq, many artifacts, many samples",UPN2_013,2,25467031,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln615Leu/c.1844A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),2504,30,2546,"0,0117831893",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,219,Tolerated,"33,24","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25467031,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln615Leu/c.1844A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),1999,23,2032,"0,0113188976",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,219,Tolerated,"33,24","17,65"
"low bq, low freq, many artifacts",UPN2_076,2,25467031,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln615Leu/c.1844A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),2052,21,2074,"0,0101253616",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,219,Tolerated,"33,22","15,05"
"low bq, low freq, many artifacts",UPN2_063,2,25467033,G,C,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp614Glu/c.1842C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),1966,20,1990,"0,0100502513",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,215,Tolerated,"32,92",14
"low bq, low freq, many artifacts, many samples",UPN2_042,2,25467034,T,A,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp614Val/c.1841A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),12113,126,12284,"0,0102572452",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,104,Tolerated,"33,71","16,58"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,25467034,T,A,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp614Val/c.1841A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10899,114,11056,"0,0103111433",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,104,Tolerated,"33,68","17,89"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,25467034,T,A,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp614Val/c.1841A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),16413,186,16637,"0,0111799002",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,104,Tolerated,"33,86","18,7"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,25467034,T,A,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp614Val/c.1841A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),11008,114,11162,"0,0102132234",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,104,Tolerated,"33,67","18,25"
"low bq, low freq, many artifacts",UPN2_060,2,25467034,T,A,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp614Val/c.1841A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),2081,24,2120,"0,0113207547",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,104,Tolerated,"33,73","19,25"
"low bq, low freq, many artifacts, many samples",UPN2_017,2,25467037,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His613Leu/c.1838A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),3141,35,3182,"0,0109993715",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,27",Deleterious,341,Tolerated,"33,99","18,8"
"low bq, low freq, many artifacts, many samples",UPN2_018,2,25467037,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His613Leu/c.1838A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),4834,52,4899,"0,0106144111",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,27",Deleterious,341,Tolerated,"33,87","16,44"
"low bq, low freq, many artifacts, many samples",UPN2_041,2,25467037,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His613Leu/c.1838A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),17107,246,17433,"0,0141111685",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,27",Deleterious,341,Tolerated,"32,84","17,38"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,25467037,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His613Leu/c.1838A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),12062,165,12280,"0,0134364821",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,27",Deleterious,341,Tolerated,"32,97","16,79"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,25467037,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His613Leu/c.1838A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),7842,119,7997,"0,0148805802",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,27",Deleterious,341,Tolerated,"32,94","18,24"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,25467037,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His613Leu/c.1838A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),2536,34,2581,"0,0131731887",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,27",Deleterious,341,Tolerated,"33,12","18,5"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,25467037,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His613Leu/c.1838A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10874,137,11053,"0,0123948249",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,27",Deleterious,341,Tolerated,"32,92","17,85"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,25467037,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His613Leu/c.1838A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),9724,140,9904,"0,0141357027",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,27",Deleterious,341,Tolerated,"32,88","17,26"
"low bq, low freq, many artifacts, many samples",UPN2_034,2,25467037,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His613Leu/c.1838A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),2092,23,2124,"0,0108286252",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,27",Deleterious,341,Tolerated,"34,22","19,65"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,25467037,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His613Leu/c.1838A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),16368,194,16637,"0,0116607561",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,27",Deleterious,341,Tolerated,"33,06","16,61"
"low bq, low freq, many artifacts, many samples",UPN2_048,2,25467037,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His613Leu/c.1838A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),15778,218,16086,"0,0135521572",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,27",Deleterious,341,Tolerated,"32,94","17,45"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,25467037,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His613Leu/c.1838A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),9885,165,10105,"0,0163285502",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,27",Deleterious,341,Tolerated,"32,73","18,65"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,25467037,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His613Leu/c.1838A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10014,179,10243,"0,017475349",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,27",Deleterious,341,Tolerated,"32,91","17,84"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,25467037,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His613Leu/c.1838A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),7763,93,7887,"0,0117915557",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,27",Deleterious,341,Tolerated,"32,89","16,68"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,25467037,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His613Leu/c.1838A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),8298,103,8443,"0,0121994552",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,27",Deleterious,341,Tolerated,"33,14","17,09"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,25467037,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His613Leu/c.1838A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10251,142,10438,"0,0136041387",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,27",Deleterious,341,Tolerated,"32,91","17,13"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,25467037,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His613Leu/c.1838A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),6443,86,6561,"0,013107758",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,27",Deleterious,341,Tolerated,"32,88","19,87"
"low bq, low freq, many artifacts, many samples",UPN2_007,2,25467037,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His613Leu/c.1838A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10202,110,10354,"0,0106239135",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,27",Deleterious,341,Tolerated,"33,22","18,18"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,25467037,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His613Leu/c.1838A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10949,162,11160,"0,014516129",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,27",Deleterious,341,Tolerated,"32,95","17,4"
"low bq, low freq, many artifacts, many samples",UPN2_056,2,25467037,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His613Leu/c.1838A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),6899,100,7033,"0,0142186833",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,27",Deleterious,341,Tolerated,"32,76","16,48"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,25467037,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His613Leu/c.1838A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),8809,136,8970,"0,0151616499",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,27",Deleterious,341,Tolerated,"33,02","17,55"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,25467037,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His613Leu/c.1838A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),7851,102,7985,"0,0127739512",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,27",Deleterious,341,Tolerated,"32,94","17,6"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25467037,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His613Leu/c.1838A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),1956,22,1990,"0,0110552764",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,27",Deleterious,341,Tolerated,"32,85","16,59"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25467037,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His613Leu/c.1838A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),1808,21,1839,"0,0114192496",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,27",Deleterious,341,Tolerated,"32,79","18,19"
"low bq, low freq, many artifacts",UPN2_083,2,25467037,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His613Leu/c.1838A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),2575,28,2619,"0,0106911035",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,27",Deleterious,341,Tolerated,"32,58","16,36"
"low bq, low freq, many artifacts, many samples",UPN2_041,2,25467040,T,A,missense_variant(MODERATE|MISSENSE|aAc/aTc|p.Asn612Ile/c.1835A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),17066,220,17429,"0,0126226404",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,0,Damaging,"31,85","16,48"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,25467040,T,A,missense_variant(MODERATE|MISSENSE|aAc/aTc|p.Asn612Ile/c.1835A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),12015,150,12278,"0,0122169734",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,0,Damaging,"31,75","17,97"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,25467040,T,A,missense_variant(MODERATE|MISSENSE|aAc/aTc|p.Asn612Ile/c.1835A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),7808,112,7996,"0,0140070035",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,0,Damaging,"31,95","16,46"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,25467040,T,A,missense_variant(MODERATE|MISSENSE|aAc/aTc|p.Asn612Ile/c.1835A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10844,131,11052,"0,0118530583",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,0,Damaging,"31,68","16,83"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,25467040,T,A,missense_variant(MODERATE|MISSENSE|aAc/aTc|p.Asn612Ile/c.1835A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),9717,109,9903,"0,0110067656",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,0,Damaging,"31,7","17,01"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,25467040,T,A,missense_variant(MODERATE|MISSENSE|aAc/aTc|p.Asn612Ile/c.1835A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),16326,196,16634,"0,0117830949",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,0,Damaging,32,"17,48"
"low bq, low freq, many artifacts, many samples",UPN2_048,2,25467040,T,A,missense_variant(MODERATE|MISSENSE|aAc/aTc|p.Asn612Ile/c.1835A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),15759,192,16082,"0,0119388136",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,0,Damaging,"31,85","17,53"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,25467040,T,A,missense_variant(MODERATE|MISSENSE|aAc/aTc|p.Asn612Ile/c.1835A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),9885,137,10103,"0,0135603286",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,0,Damaging,"31,7","17,74"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,25467040,T,A,missense_variant(MODERATE|MISSENSE|aAc/aTc|p.Asn612Ile/c.1835A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10034,125,10237,"0,0122106086",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,0,Damaging,"31,76","16,42"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,25467040,T,A,missense_variant(MODERATE|MISSENSE|aAc/aTc|p.Asn612Ile/c.1835A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),7746,85,7885,"0,010779962",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,0,Damaging,"31,89","16,85"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,25467040,T,A,missense_variant(MODERATE|MISSENSE|aAc/aTc|p.Asn612Ile/c.1835A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10229,137,10436,"0,0131276351",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,0,Damaging,"31,76","17,8"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,25467040,T,A,missense_variant(MODERATE|MISSENSE|aAc/aTc|p.Asn612Ile/c.1835A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),6428,76,6561,"0,0115836001",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,0,Damaging,"31,68","15,99"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,25467040,T,A,missense_variant(MODERATE|MISSENSE|aAc/aTc|p.Asn612Ile/c.1835A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10942,140,11157,"0,012548176",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,0,Damaging,"31,95","16,64"
"low bq, low freq, many artifacts, many samples",UPN2_056,2,25467040,T,A,missense_variant(MODERATE|MISSENSE|aAc/aTc|p.Asn612Ile/c.1835A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),6907,79,7031,"0,0112359551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,0,Damaging,"31,7","16,18"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,25467040,T,A,missense_variant(MODERATE|MISSENSE|aAc/aTc|p.Asn612Ile/c.1835A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),8813,113,8969,"0,0125989519",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,0,Damaging,"31,9","16,91"
"low bq, low freq, many artifacts",UPN2_058,2,25467040,T,A,missense_variant(MODERATE|MISSENSE|aAc/aTc|p.Asn612Ile/c.1835A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),7841,90,7982,"0,0112753696",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,0,Damaging,32,"16,52"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,25467041,T,A,missense_variant(MODERATE|MISSENSE|Aac/Tac|p.Asn612Tyr/c.1834A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),9772,107,9903,"0,0108048066",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,26",Deleterious,1,Damaging,"33,34","17,79"
"low bq, low freq, many artifacts, many samples",UPN2_048,2,25467041,T,A,missense_variant(MODERATE|MISSENSE|Aac/Tac|p.Asn612Tyr/c.1834A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),15850,169,16081,"0,0105092967",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,26",Deleterious,1,Damaging,"33,44","18,69"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,25467041,T,A,missense_variant(MODERATE|MISSENSE|Aac/Tac|p.Asn612Tyr/c.1834A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),9959,106,10102,"0,0104929717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,26",Deleterious,1,Damaging,"33,42","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,25467041,T,A,missense_variant(MODERATE|MISSENSE|Aac/Tac|p.Asn612Tyr/c.1834A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),6462,69,6561,"0,0105166895",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,26",Deleterious,1,Damaging,"33,19","17,72"
"low bq, low freq, many artifacts",UPN2_057,2,25467041,T,A,missense_variant(MODERATE|MISSENSE|Aac/Tac|p.Asn612Tyr/c.1834A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),8848,90,8968,"0,0100356824",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,26",Deleterious,1,Damaging,"33,31","17,86"
"low bq, low freq, many artifacts, many samples",UPN2_001,2,25467043,T,A,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn611Ile/c.1832A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),3460,37,3511,"0,0105383082",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,38,Damaging,"32,93","16,16"
"low bq, low freq, many artifacts, many samples",UPN2_016,2,25467043,T,A,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn611Ile/c.1832A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),4408,56,4488,"0,0124777184",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,38,Damaging,"33,51","17,07"
"low bq, low freq, many artifacts, many samples",UPN2_018,2,25467043,T,A,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn611Ile/c.1832A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),4820,53,4899,"0,0108185344",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,38,Damaging,"33,38","17,92"
"low bq, low freq, many artifacts, many samples",UPN2_022,2,25467043,T,A,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn611Ile/c.1832A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),5824,62,5921,"0,0104712042",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,38,Damaging,"33,53","15,98"
"low bq, low freq, many artifacts, many samples",UPN2_041,2,25467043,T,A,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn611Ile/c.1832A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),17090,264,17427,"0,0151489069",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,38,Damaging,"32,31","16,9"
"low bq, low freq, many artifacts, many samples",UPN2_024,2,25467043,T,A,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn611Ile/c.1832A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),3536,41,3597,"0,0113983875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,38,Damaging,"33,47","16,9"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,25467043,T,A,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn611Ile/c.1832A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),11993,193,12276,"0,0157217335",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,38,Damaging,"32,19","17,97"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,25467043,T,A,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn611Ile/c.1832A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),7823,123,7995,"0,0153846154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,38,Damaging,"32,34","16,26"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,25467043,T,A,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn611Ile/c.1832A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),2531,34,2578,"0,0131885182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,38,Damaging,"32,44","16,15"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,25467043,T,A,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn611Ile/c.1832A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10834,167,11050,"0,0151131222",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,38,Damaging,"32,35","16,95"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,25467043,T,A,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn611Ile/c.1832A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),9729,125,9902,"0,0126237124",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,38,Damaging,"32,24","16,34"
"low bq, low freq, many artifacts, many samples",UPN2_033,2,25467043,T,A,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn611Ile/c.1832A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),5541,64,5634,"0,0113596024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,38,Damaging,"33,35","17,16"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,25467043,T,A,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn611Ile/c.1832A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),16258,284,16632,"0,0170755171",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,38,Damaging,"32,33","17,07"
"low bq, low freq, many artifacts, many samples",UPN2_048,2,25467043,T,A,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn611Ile/c.1832A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),15719,254,16079,"0,0157970023",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,38,Damaging,"32,26","17,17"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,25467043,T,A,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn611Ile/c.1832A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),9901,148,10102,"0,0146505642",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,38,Damaging,"32,17","17,22"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,25467043,T,A,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn611Ile/c.1832A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10026,155,10236,"0,0151426338",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,38,Damaging,"32,24","17,2"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,25467043,T,A,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn611Ile/c.1832A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),7721,121,7883,"0,0153494862",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,38,Damaging,"32,33","16,9"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,25467043,T,A,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn611Ile/c.1832A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),8282,120,8442,"0,0142146411",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,38,Damaging,"32,26","17,23"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,25467043,T,A,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn611Ile/c.1832A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10226,149,10435,"0,0142788692",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,38,Damaging,"32,22","17,49"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,25467043,T,A,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn611Ile/c.1832A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),6418,105,6559,"0,0160085379",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,38,Damaging,"32,08","16,67"
"low bq, low freq, many artifacts, many samples",UPN2_007,2,25467043,T,A,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn611Ile/c.1832A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10191,113,10352,"0,0109157651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,38,Damaging,"32,87","16,15"
"low bq, low freq, many artifacts, many samples",UPN2_008,2,25467043,T,A,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn611Ile/c.1832A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),15073,186,15336,"0,0121283255",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,38,Damaging,"32,99","16,97"
"low bq, low freq, many artifacts, many samples",UPN2_009,2,25467043,T,A,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn611Ile/c.1832A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),12209,129,12401,"0,0104023869",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,38,Damaging,"32,96","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,25467043,T,A,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn611Ile/c.1832A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10941,149,11154,"0,0133584364",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,38,Damaging,"32,36","16,26"
"low bq, low freq, many artifacts, many samples",UPN2_056,2,25467043,T,A,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn611Ile/c.1832A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),6894,111,7030,"0,0157894737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,38,Damaging,"32,25","18,14"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,25467043,T,A,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn611Ile/c.1832A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),8760,156,8967,"0,0173971228",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,38,Damaging,"32,28","16,33"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,25467043,T,A,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn611Ile/c.1832A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),7803,128,7982,"0,0160360812",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,38,Damaging,"32,27","18,16"
"low bq, low freq, many artifacts, many samples",UPN2_012,2,25467043,T,A,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn611Ile/c.1832A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),4881,51,4965,"0,0102719033",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,38,Damaging,"32,92","15,78"
"low bq, low freq, many artifacts, many samples",UPN2_013,2,25467043,T,A,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn611Ile/c.1832A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),2496,34,2544,"0,0133647799",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,38,Damaging,"32,73","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25467043,T,A,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn611Ile/c.1832A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),1922,21,1958,"0,0107252298",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,38,Damaging,"32,26","17,14"
"low bq, low freq, many artifacts",UPN2_073,2,25467043,T,A,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn611Ile/c.1832A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),1743,21,1773,"0,0118443316",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,38,Damaging,"32,89","16,1"
"low bq, low freq, many artifacts",UPN2_051,2,25467044,T,A,missense_variant(MODERATE|MISSENSE|Aat/Tat|p.Asn611Tyr/c.1831A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),7769,86,7882,"0,0109109363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,2,Damaging,"33,36","19,69"
"inspected, many artifacts",UPN2_072,2,25467047,C,T,missense_variant(MODERATE|MISSENSE|Gct/Act|p.Ala610Thr/c.1828G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|T),2902,35,2946,"0,011880516",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,22",Neutral,"0,554",Tolerated,"33,65","33,74"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,25467052,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe608Cys/c.1823T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),1214,21,1242,"0,0169082126",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,9",Deleterious,0,Damaging,"28,16",14
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25467052,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe608Cys/c.1823T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2084,27,2119,"0,0127418594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,9",Deleterious,0,Damaging,"28,33","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25467052,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe608Cys/c.1823T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),1916,32,1956,"0,0163599182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,9",Deleterious,0,Damaging,28,"16,34"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25467052,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe608Cys/c.1823T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),1987,39,2030,"0,0192118227",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,9",Deleterious,0,Damaging,"28,17","14,18"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25467052,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe608Cys/c.1823T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),1955,32,1989,"0,0160884867",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,9",Deleterious,0,Damaging,"28,25","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25467052,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe608Cys/c.1823T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),1809,25,1838,"0,013601741",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,9",Deleterious,0,Damaging,"28,36","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25467052,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe608Cys/c.1823T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2743,42,2796,"0,0150214592",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,9",Deleterious,0,Damaging,"28,1",14
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25467052,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe608Cys/c.1823T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2899,35,2946,"0,011880516",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,9",Deleterious,0,Damaging,"28,08",14
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25467052,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe608Cys/c.1823T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),1747,22,1773,"0,0124083474",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,9",Deleterious,0,Damaging,"28,42","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25467052,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe608Cys/c.1823T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2832,33,2872,"0,0114902507",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,9",Deleterious,0,Damaging,"28,46","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25467052,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe608Cys/c.1823T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2040,26,2072,"0,0125482625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,9",Deleterious,0,Damaging,"28,46","15,88"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25467052,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe608Cys/c.1823T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),1652,24,1680,"0,0142857143",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,9",Deleterious,0,Damaging,"28,28",14
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25467052,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe608Cys/c.1823T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2181,25,2214,"0,0112917796",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,9",Deleterious,0,Damaging,"28,07",14
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25467052,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe608Cys/c.1823T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2461,28,2497,"0,0112134561",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,9",Deleterious,0,Damaging,"28,03",14
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25467052,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe608Cys/c.1823T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),3739,49,3797,"0,0129049249",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,9",Deleterious,0,Damaging,"27,98","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25467052,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe608Cys/c.1823T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2566,41,2615,"0,0156787763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,9",Deleterious,0,Damaging,"28,25","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_087,2,25467052,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe608Cys/c.1823T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2012,30,2051,"0,0146270112",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,9",Deleterious,0,Damaging,"28,05",14
"low bq, low freq, many artifacts",UPN2_088,2,25467052,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe608Cys/c.1823T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),1090,20,1115,"0,0179372197",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,9",Deleterious,0,Damaging,"28,19","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_018,2,25467056,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met607Leu/c.1819A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),4827,50,4898,"0,0102082483",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,306,Tolerated,"34,09","18,8"
"low bq, low freq, many artifacts, many samples",UPN2_041,2,25467056,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met607Leu/c.1819A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),17110,253,17409,"0,014532713",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,306,Tolerated,"32,83","18,91"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,25467056,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met607Leu/c.1819A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),12038,178,12269,"0,0145081099",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,306,Tolerated,"32,92","16,72"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,25467056,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met607Leu/c.1819A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),7870,101,7991,"0,0126392191",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,306,Tolerated,"32,7","16,07"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,25467056,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met607Leu/c.1819A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),2540,26,2574,"0,0101010101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,306,Tolerated,"32,78","16,46"
"low bq, low freq, many artifacts, many samples",UPN2_005,2,25467056,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met607Leu/c.1819A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),1572,20,1596,"0,0125313283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,306,Tolerated,"33,76","15,25"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,25467056,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met607Leu/c.1819A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10890,126,11044,"0,0114089098",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,306,Tolerated,"32,91","16,34"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,25467056,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met607Leu/c.1819A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),9754,105,9896,"0,0106103476",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,306,Tolerated,"32,85","17,8"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,25467056,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met607Leu/c.1819A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),16381,186,16623,"0,011189316",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,306,Tolerated,"32,8","16,13"
"low bq, low freq, many artifacts, many samples",UPN2_048,2,25467056,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met607Leu/c.1819A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),15835,189,16070,"0,0117610454",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,306,Tolerated,"32,88","16,94"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,25467056,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met607Leu/c.1819A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),9934,118,10091,"0,0116935883",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,306,Tolerated,"32,75","17,57"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,25467056,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met607Leu/c.1819A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10076,126,10229,"0,0123179196",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,306,Tolerated,"32,83","17,24"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,25467056,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met607Leu/c.1819A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),7743,107,7874,"0,0135890272",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,306,Tolerated,"32,7","16,74"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,25467056,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met607Leu/c.1819A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),8309,96,8434,"0,0113824994",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,306,Tolerated,"32,8","17,6"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,25467056,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met607Leu/c.1819A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10263,125,10421,"0,0119950101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,306,Tolerated,"32,88","15,68"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,25467056,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met607Leu/c.1819A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),6444,87,6555,"0,0132723112",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,306,Tolerated,"32,81","17,09"
"low bq, low freq, many artifacts, many samples",UPN2_007,2,25467056,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met607Leu/c.1819A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10201,121,10349,"0,0116919509",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,306,Tolerated,"33,72","17,25"
"low bq, low freq, many artifacts, many samples",UPN2_008,2,25467056,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met607Leu/c.1819A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),15129,165,15333,"0,0107611035",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,306,Tolerated,"33,66","16,53"
"low bq, low freq, many artifacts, many samples",UPN2_009,2,25467056,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met607Leu/c.1819A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),12223,136,12397,"0,0109703961",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,306,Tolerated,"33,7","18,24"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,25467056,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met607Leu/c.1819A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10974,134,11148,"0,0120200933",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,306,Tolerated,"32,82","17,98"
"low bq, low freq, many artifacts, many samples",UPN2_056,2,25467056,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met607Leu/c.1819A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),6904,105,7026,"0,0149444919",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,306,Tolerated,"32,89","16,5"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,25467056,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met607Leu/c.1819A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),8816,110,8962,"0,012274046",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,306,Tolerated,"32,81","17,15"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,25467056,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met607Leu/c.1819A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),7837,111,7977,"0,0139150056",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,306,Tolerated,"32,7","21,14"
"low bq, low freq, many artifacts",UPN2_013,2,25467056,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met607Leu/c.1819A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),2506,34,2544,"0,0133647799",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,306,Tolerated,"33,79","16,59"
"low bq, low freq, many artifacts, many samples",UPN2_001,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),3436,56,3508,"0,015963512",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"31,22","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_014,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),6759,130,6911,"0,0188105918",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"31,38","17,07"
"low bq, low freq, many artifacts, many samples",UPN2_015,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),9245,146,9415,"0,0155071694",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"31,51","17,47"
"low bq, low freq, many artifacts, many samples",UPN2_016,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),4402,65,4486,"0,014489523",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"31,11","16,14"
"low bq, low freq, many artifacts, many samples",UPN2_017,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),3116,51,3180,"0,0160377358",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"30,96","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_018,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),4797,86,4898,"0,017558187",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"31,3","16,88"
"low bq, low freq, many artifacts, many samples",UPN2_019,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),5005,63,5078,"0,0124064592",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"31,39","17,06"
"low bq, low freq, many artifacts, many samples",UPN2_020,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),4771,75,4861,"0,0154289241",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"30,91","17,51"
"low bq, low freq, many artifacts, many samples",UPN2_021,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),5444,75,5536,"0,0135476879",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"31,28","16,56"
"low bq, low freq, many artifacts, many samples",UPN2_002,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),4508,92,4609,"0,019960946",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"31,56","16,35"
"low bq, low freq, many artifacts, many samples",UPN2_022,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),5813,92,5919,"0,0155431661",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"31,21","17,59"
"low bq, low freq, many artifacts, many samples",UPN2_023,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),7022,123,7168,"0,0171595982",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"31,38","16,67"
"low bq, many samples",UPN2_041,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),16874,464,17404,"0,0266605378",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"29,58","16,6"
"low bq, low freq, many artifacts, many samples",UPN2_024,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),3519,62,3595,"0,0172461752",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"31,09","16,63"
"low bq, low freq, many artifacts, many samples",UPN2_025,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),8639,136,8796,"0,0154615734",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"31,17","16,4"
"low bq, low freq, many artifacts, many samples",UPN2_026,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),8424,145,8584,"0,0168918919",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"31,38","17,14"
"low bq, low freq, many artifacts, many samples",UPN2_027,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),8455,117,8608,"0,0135920074",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"31,46","17,24"
"low bq, many samples",UPN2_042,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),11917,308,12266,"0,0251100603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"29,67","16,73"
"low bq, low freq, many artifacts, many samples",UPN2_028,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),5920,74,6008,"0,0123169108",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"31,44","18,58"
"low bq, many samples",UPN2_043,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),7731,220,7987,"0,0275447602",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"29,42","17,23"
"low bq, many samples",UPN2_044,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),2506,64,2574,"0,0248640249",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"29,23","15,62"
"low bq, low freq, many artifacts, many samples",UPN2_029,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),7747,121,7896,"0,0153242148",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"31,23","16,61"
"low bq, low freq, many artifacts, many samples",UPN2_030,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),7557,123,7703,"0,0159678048",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"31,3","16,17"
"low bq, low freq, many artifacts, many samples",UPN2_031,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),4752,84,4849,"0,0173231594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"31,36","16,26"
"low bq, many samples",UPN2_005,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),1556,36,1596,"0,022556391",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"31,27","16,31"
"low bq, many samples",UPN2_045,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10728,269,11039,"0,0243681493",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"29,75","16,13"
"low bq, low freq, many artifacts, many samples",UPN2_032,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),2821,42,2873,"0,0146188653",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"31,16","15,79"
"low bq, many samples",UPN2_046,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),9577,273,9889,"0,0276064314",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"29,72","15,99"
"low bq, low freq, many artifacts, many samples",UPN2_033,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),5505,105,5632,"0,0186434659",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"31,05","17,93"
"low bq, low freq, many artifacts, many samples",UPN2_034,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),2093,24,2124,"0,011299435",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"31,25","17,5"
"low bq, many samples",UPN2_047,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),16106,440,16614,"0,0264836885",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"29,38","17,18"
"low bq, many samples",UPN2_048,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),15534,457,16064,"0,0284487052",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"29,69","17,62"
"low bq, low freq, many artifacts, many samples",UPN2_035,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),6800,108,6938,"0,0155664457",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"31,16","17,24"
"low bq, low freq, many artifacts, many samples",UPN2_036,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),9926,165,10142,"0,0162689805",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"31,23","17,59"
"low bq, low freq, many artifacts, many samples",UPN2_006,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),3278,70,3357,"0,0208519511",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"31,42","18,96"
"low bq, many samples",UPN2_049,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),9750,302,10089,"0,029933591",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"29,58","16,77"
"low bq, many samples",UPN2_050,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),9894,284,10222,"0,0277832127",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"29,58","16,29"
"low bq, low freq, many artifacts, many samples",UPN2_037,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),12462,212,12719,"0,016667977",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"31,21","17,36"
"low bq, many samples",UPN2_051,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),7588,238,7871,"0,030237581",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"29,53","16,64"
"low bq, many samples",UPN2_052,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),8219,189,8434,"0,0224092957",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"29,58","15,72"
"low bq, low freq, many artifacts, many samples",UPN2_038,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),12089,167,12297,"0,0135805481",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"31,28","17,96"
"low bq, low freq, many artifacts, many samples",UPN2_039,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),9051,141,9215,"0,0153011394",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"31,37","18,36"
"low bq, many samples",UPN2_053,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10093,290,10416,"0,0278417819",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"29,57","17,48"
"low bq, many samples",UPN2_054,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),6366,170,6554,"0,0259383583",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"29,68","17,04"
"low bq, low freq, many artifacts, many samples",UPN2_007,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10121,195,10347,"0,0188460423",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"31,23","17,01"
"low bq, low freq, many artifacts, many samples",UPN2_008,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),14989,292,15331,"0,0190463766",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"31,31","16,27"
"low bq, low freq, many artifacts, many samples",UPN2_009,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),12146,224,12396,"0,0180703453",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"31,43","15,83"
"low bq, low freq, many artifacts, many samples",UPN2_010,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),7247,135,7399,"0,0182457089",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"31,45","16,84"
"low bq, low freq, many artifacts, many samples",UPN2_011,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),9270,163,9471,"0,0172104318",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"31,18","16,01"
"low bq, many samples",UPN2_055,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10786,317,11146,"0,0284406962",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"29,52","16,17"
"low bq, many samples",UPN2_056,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),6800,181,7024,"0,0257687927",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"29,65","16,2"
"low bq, low freq, many artifacts, many samples",UPN2_090,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),4623,50,4682,"0,0106791969",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"33,26","21,4"
"low bq, many samples",UPN2_057,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),8685,239,8954,"0,0266919812",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"29,48","17,89"
"low bq, many samples",UPN2_058,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),7747,199,7973,"0,0249592374",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"29,25","16,18"
"low bq, low freq, many artifacts, many samples",UPN2_012,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),4871,80,4964,"0,0161160355",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"31,27","16,76"
"low bq, low freq, many artifacts, many samples",UPN2_040,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),4245,67,4319,"0,0155128502",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,31,"17,99"
"low bq, low freq, many artifacts, many samples",UPN2_013,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),2499,37,2544,"0,0145440252",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"31,1","16,51"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),2114,22,2141,"0,0102755722",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"32,94","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),2754,29,2795,"0,0103756708",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"32,63","15,52"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),2830,29,2870,"0,0101045296",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"32,48","16,76"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),3737,45,3797,"0,0118514617",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"32,43","16,33"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),1220,20,1247,"0,0160384924",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"32,65","19,95"
"low bq, low freq, many artifacts",UPN2_083,2,25467058,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln606Leu/c.1817A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),2574,28,2613,"0,0107156525",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,31,Damaging,"32,37","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25467059,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln606Glu/c.1816C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2085,27,2118,"0,0127478754",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,11,Damaging,"31,73",14
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25467059,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln606Glu/c.1816C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),1995,23,2028,"0,0113412229",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,11,Damaging,"31,61","15,65"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25467059,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln606Glu/c.1816C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),1805,21,1837,"0,0114316821",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,11,Damaging,"32,12","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25467059,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln606Glu/c.1816C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2902,31,2944,"0,0105298913",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,11,Damaging,"31,8","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25467059,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln606Glu/c.1816C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),1744,23,1772,"0,012979684",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,11,Damaging,"31,83","15,17"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25467059,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln606Glu/c.1816C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2832,29,2870,"0,0101045296",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,11,Damaging,"31,69",14
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25467059,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln606Glu/c.1816C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),3744,38,3797,"0,010007901",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,11,Damaging,"31,7","14,89"
"low bq, low freq, many artifacts",UPN2_083,2,25467059,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln606Glu/c.1816C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2574,34,2613,"0,0130118638",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,11,Damaging,"31,62",14
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25467061,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu605Arg/c.1814T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2086,26,2117,"0,0122815305",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,33",Deleterious,0,Damaging,"27,79",14
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25467061,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu605Arg/c.1814T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),1926,27,1954,"0,0138178096",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,33",Deleterious,0,Damaging,"28,04","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25467061,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu605Arg/c.1814T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),1974,38,2027,"0,0187469166",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,33",Deleterious,0,Damaging,"27,64","15,39"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25467061,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu605Arg/c.1814T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),1958,22,1986,"0,0110775428",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,33",Deleterious,0,Damaging,"28,05",14
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25467061,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu605Arg/c.1814T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),1812,22,1837,"0,0119760479",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,33",Deleterious,0,Damaging,"28,29","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25467061,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu605Arg/c.1814T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2098,31,2140,"0,0144859813",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,33",Deleterious,0,Damaging,"28,07","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25467061,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu605Arg/c.1814T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2742,39,2793,"0,0139634801",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,33",Deleterious,0,Damaging,"28,25","15,56"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25467061,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu605Arg/c.1814T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2894,32,2944,"0,0108695652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,33",Deleterious,0,Damaging,"27,98","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25467061,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu605Arg/c.1814T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),1747,20,1772,"0,0112866817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,33",Deleterious,0,Damaging,"28,4",14
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25467061,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu605Arg/c.1814T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2824,38,2870,"0,0132404181",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,33",Deleterious,0,Damaging,"28,34","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25467061,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu605Arg/c.1814T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2043,23,2071,"0,011105746",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,33",Deleterious,0,Damaging,"28,38","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25467061,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu605Arg/c.1814T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2176,26,2212,"0,0117540687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,33",Deleterious,0,Damaging,"27,98",14
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25467061,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu605Arg/c.1814T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),1312,21,1338,"0,0156950673",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,33",Deleterious,0,Damaging,"28,24",14
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25467061,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu605Arg/c.1814T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),3737,47,3796,"0,0123814542",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,33",Deleterious,0,Damaging,"28,13",15
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25467061,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu605Arg/c.1814T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2577,29,2613,"0,0110983544",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,33",Deleterious,0,Damaging,"28,18",14
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25467061,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu605Arg/c.1814T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),1873,21,1900,"0,0110526316",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,33",Deleterious,0,Damaging,"28,3",14
"low bq, low freq, many artifacts",UPN2_087,2,25467061,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu605Arg/c.1814T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2021,22,2049,"0,0107369449",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,33",Deleterious,0,Damaging,"27,66","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25467068,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser603Ala/c.1807T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),1996,21,2026,"0,0103652517",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,398,Tolerated,"30,21","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25467068,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser603Ala/c.1807T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2754,31,2792,"0,0111031519",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,398,Tolerated,"29,91","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25467068,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser603Ala/c.1807T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2894,31,2942,"0,0105370496",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,398,Tolerated,"30,43",16
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25467074,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp601Gly/c.1801T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2737,30,2792,"0,0107449857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-11,85",Deleterious,15,Damaging,"30,29","15,57"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25467074,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp601Gly/c.1801T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2036,22,2067,"0,0106434446",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-11,85",Deleterious,15,Damaging,"30,83","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25467074,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp601Gly/c.1801T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2174,28,2210,"0,0126696833",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-11,85",Deleterious,15,Damaging,"30,24","15,36"
"low bq, low freq, many artifacts",UPN2_083,2,25467074,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp601Gly/c.1801T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2567,27,2608,"0,0103527607",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-11,85",Deleterious,15,Damaging,"30,28","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,25467075,G,C,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp600Glu/c.1800C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2538,28,2573,"0,0108822386",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,73",Deleterious,1,Damaging,"31,65","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,25467075,G,C,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp600Glu/c.1800C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),10879,111,11021,"0,0100716813",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,73",Deleterious,1,Damaging,"32,06","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,25467075,G,C,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp600Glu/c.1800C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),16361,177,16583,"0,0106735814",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,73",Deleterious,1,Damaging,"32,06","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_041,2,25467076,T,A,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp600Val/c.1799A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),17068,211,17355,"0,0121578796",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,46",Deleterious,0,Damaging,"32,83","16,06"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,25467076,T,A,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp600Val/c.1799A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),12050,149,12239,"0,0121741972",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,46",Deleterious,0,Damaging,"32,85","15,85"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,25467076,T,A,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp600Val/c.1799A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),7832,110,7973,"0,0137965634",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,46",Deleterious,0,Damaging,"32,79","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,25467076,T,A,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp600Val/c.1799A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10831,136,11018,"0,012343438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,46",Deleterious,0,Damaging,"32,88","15,39"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,25467076,T,A,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp600Val/c.1799A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),9722,111,9872,"0,0112439222",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,46",Deleterious,0,Damaging,"32,81","16,05"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,25467076,T,A,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp600Val/c.1799A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),16296,204,16578,"0,0123054651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,46",Deleterious,0,Damaging,"32,93","17,07"
"low bq, low freq, many artifacts, many samples",UPN2_048,2,25467076,T,A,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp600Val/c.1799A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),15741,212,16047,"0,0132111921",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,46",Deleterious,0,Damaging,"32,94","16,52"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,25467076,T,A,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp600Val/c.1799A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),9881,149,10071,"0,0147949558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,46",Deleterious,0,Damaging,"32,75","16,23"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,25467076,T,A,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp600Val/c.1799A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10049,112,10205,"0,0109750122",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,46",Deleterious,0,Damaging,"32,76","15,88"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,25467076,T,A,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp600Val/c.1799A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),7724,102,7853,"0,0129886668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,46",Deleterious,0,Damaging,"32,89","16,38"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,25467076,T,A,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp600Val/c.1799A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),8305,92,8423,"0,0109224742",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,46",Deleterious,0,Damaging,"32,75","15,34"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,25467076,T,A,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp600Val/c.1799A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10194,144,10393,"0,0138554796",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,46",Deleterious,0,Damaging,"32,74","17,37"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,25467076,T,A,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp600Val/c.1799A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),6455,70,6546,"0,0106935533",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,46",Deleterious,0,Damaging,"32,66","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_007,2,25467076,T,A,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp600Val/c.1799A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10192,108,10339,"0,0104458845",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,46",Deleterious,0,Damaging,"33,61","16,57"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,25467076,T,A,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp600Val/c.1799A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10940,135,11125,"0,0121348315",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,46",Deleterious,0,Damaging,"32,87","15,91"
"low bq, low freq, many artifacts, many samples",UPN2_056,2,25467076,T,A,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp600Val/c.1799A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),6888,77,7009,"0,0109858753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,46",Deleterious,0,Damaging,"32,76","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,25467076,T,A,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp600Val/c.1799A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),8783,123,8941,"0,0137568505",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,46",Deleterious,0,Damaging,"32,73","15,45"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,25467076,T,A,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp600Val/c.1799A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),7851,95,7965,"0,0119271814",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,46",Deleterious,0,Damaging,"32,78","16,27"
"low bq, low freq, many artifacts, many samples",UPN2_013,2,25467076,T,A,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp600Val/c.1799A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),2510,28,2541,"0,0110192837",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,46",Deleterious,0,Damaging,"33,64","17,18"
"low bq, low freq, many artifacts",UPN2_069,2,25467076,T,A,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp600Val/c.1799A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),2100,23,2137,"0,0107627515",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,46",Deleterious,0,Damaging,"33,21","18,78"
"low bq, low freq, many artifacts, many samples",UPN2_001,2,25467079,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu599Val/c.1796A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),3437,38,3500,"0,0108571429",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,37",Deleterious,"0,08",Tolerated,"33,16","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_041,2,25467079,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu599Val/c.1796A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),17055,220,17350,"0,0126801153",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,37",Deleterious,"0,08",Tolerated,"31,74","16,27"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,25467079,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu599Val/c.1796A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),12017,157,12237,"0,012829942",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,37",Deleterious,"0,08",Tolerated,"31,79","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,25467079,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu599Val/c.1796A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),7827,101,7968,"0,0126757028",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,37",Deleterious,"0,08",Tolerated,"31,79","15,93"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,25467079,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu599Val/c.1796A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),2524,31,2571,"0,0120575651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,37",Deleterious,"0,08",Tolerated,"31,61","17,06"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,25467079,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu599Val/c.1796A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10817,138,11014,"0,0125295079",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,37",Deleterious,"0,08",Tolerated,"31,95","16,23"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,25467079,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu599Val/c.1796A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),9710,111,9867,"0,0112496199",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,37",Deleterious,"0,08",Tolerated,"31,78","16,05"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,25467079,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu599Val/c.1796A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),16298,184,16575,"0,0111010558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,37",Deleterious,"0,08",Tolerated,"31,91","16,62"
"low bq, low freq, many artifacts, many samples",UPN2_048,2,25467079,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu599Val/c.1796A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),15719,218,16044,"0,013587634",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,37",Deleterious,"0,08",Tolerated,"31,86","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,25467079,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu599Val/c.1796A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),9880,144,10067,"0,0143041621",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,37",Deleterious,"0,08",Tolerated,"31,86","16,88"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,25467079,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu599Val/c.1796A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10032,118,10201,"0,0115674934",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,37",Deleterious,"0,08",Tolerated,"31,81","16,54"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,25467079,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu599Val/c.1796A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),7711,104,7852,"0,0132450331",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,37",Deleterious,"0,08",Tolerated,"31,87","15,88"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,25467079,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu599Val/c.1796A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),8287,102,8418,"0,0121168924",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,37",Deleterious,"0,08",Tolerated,"31,84","15,96"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,25467079,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu599Val/c.1796A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10222,114,10388,"0,010974201",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,37",Deleterious,"0,08",Tolerated,"31,79","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,25467079,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu599Val/c.1796A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),6440,71,6543,"0,0108512915",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,37",Deleterious,"0,08",Tolerated,"31,76","17,82"
"low bq, low freq, many artifacts, many samples",UPN2_007,2,25467079,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu599Val/c.1796A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10187,106,10336,"0,010255418",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,37",Deleterious,"0,08",Tolerated,"33,13","15,93"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,25467079,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu599Val/c.1796A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),10936,142,11123,"0,01276634",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,37",Deleterious,"0,08",Tolerated,"31,81","15,82"
"low bq, low freq, many artifacts, many samples",UPN2_056,2,25467079,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu599Val/c.1796A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),6881,95,7007,"0,0135578707",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,37",Deleterious,"0,08",Tolerated,"31,95","15,99"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,25467079,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu599Val/c.1796A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),8784,105,8939,"0,0117462803",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,37",Deleterious,"0,08",Tolerated,"31,76","15,5"
"low bq, low freq, many artifacts",UPN2_058,2,25467079,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu599Val/c.1796A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),7838,90,7963,"0,011302273",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,37",Deleterious,"0,08",Tolerated,"31,79","15,56"
"not in 2nd Illumina, low freq, no database",UPN2_006,2,25467082,C,A,missense_variant(MODERATE|MISSENSE|cGa/cTa|p.Arg598Leu/c.1793G>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),3315,47,3369,"0,0139507272",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,62",Deleterious,0,Damaging,"33,43","32,66"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,25467091,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu595Arg/c.1784T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2457,31,2499,"0,012404962",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,0,Damaging,"28,92",14
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25467091,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu595Arg/c.1784T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),4174,59,4257,"0,0138595255",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,0,Damaging,"28,97","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25467091,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu595Arg/c.1784T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),3886,43,3940,"0,0109137056",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,0,Damaging,"29,14","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25467091,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu595Arg/c.1784T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),4024,50,4087,"0,0122339124",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,0,Damaging,"29,03","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25467091,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu595Arg/c.1784T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),3923,50,3993,"0,0125219133",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,0,Damaging,"29,33","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25467091,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu595Arg/c.1784T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),3626,42,3698,"0,0113574905",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,0,Damaging,"29,1",14
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25467091,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu595Arg/c.1784T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2210,27,2255,"0,0119733925",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,0,Damaging,"29,49","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25467091,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu595Arg/c.1784T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),4238,57,4319,"0,0131974994",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,0,Damaging,"29,29","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,25467091,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu595Arg/c.1784T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2304,35,2351,"0,014887282",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,0,Damaging,"29,16","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25467091,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu595Arg/c.1784T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),5533,75,5621,"0,0133428216",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,0,Damaging,"29,33","14,19"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25467091,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu595Arg/c.1784T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),5830,74,5930,"0,0124789207",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,0,Damaging,"29,3","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25467091,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu595Arg/c.1784T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),3511,44,3569,"0,0123283833",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,0,Damaging,"29,24","15,59"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,25467091,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu595Arg/c.1784T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),1545,22,1579,"0,0139328689",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,0,Damaging,"28,91","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25467091,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu595Arg/c.1784T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),5677,63,5782,"0,0108958838",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,0,Damaging,"29,57","17,02"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25467091,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu595Arg/c.1784T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),4085,59,4162,"0,014175877",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,0,Damaging,"29,07","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25467091,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu595Arg/c.1784T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),3325,42,3377,"0,0124370743",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,0,Damaging,"29,3","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25467091,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu595Arg/c.1784T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),4368,53,4450,"0,0119101124",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,0,Damaging,"29,1","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25467091,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu595Arg/c.1784T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2649,30,2696,"0,0111275964",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,0,Damaging,"29,36","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25467091,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu595Arg/c.1784T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),4939,53,5010,"0,0105788423",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,0,Damaging,"29,31","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25467091,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu595Arg/c.1784T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),7523,97,7655,"0,0126714566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,0,Damaging,"29,15","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25467091,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu595Arg/c.1784T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2468,35,2522,"0,0138778747",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,0,Damaging,"29,38",14
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25467091,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu595Arg/c.1784T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),5160,63,5255,"0,0119885823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,0,Damaging,"29,1","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25467091,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu595Arg/c.1784T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),3766,41,3826,"0,0107161526",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,0,Damaging,"29,18","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,25467091,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu595Arg/c.1784T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2263,30,2309,"0,0129926375",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,0,Damaging,"29,08","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_087,2,25467091,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu595Arg/c.1784T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),4045,46,4120,"0,0111650485",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,0,Damaging,"29,05","15,24"
"low bq, low freq, many artifacts",UPN2_088,2,25467091,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu595Arg/c.1784T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2209,28,2246,"0,0124666073",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,0,Damaging,"29,22","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,25467094,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu594Arg/c.1781T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2462,29,2499,"0,0116046419",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,75",Deleterious,1,Damaging,"29,5","15,9"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25467094,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu594Arg/c.1781T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),4172,64,4259,"0,0150270016",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,75",Deleterious,1,Damaging,"29,5","15,56"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25467094,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu594Arg/c.1781T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),3869,53,3940,"0,0134517766",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,75",Deleterious,1,Damaging,"29,54","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25467094,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu594Arg/c.1781T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),3981,81,4087,"0,0198189381",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,75",Deleterious,1,Damaging,"29,45","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25467094,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu594Arg/c.1781T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),3924,50,3993,"0,0125219133",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,75",Deleterious,1,Damaging,"29,79","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25467094,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu594Arg/c.1781T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),3617,55,3697,"0,0148769272",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,75",Deleterious,1,Damaging,"29,48","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,25467094,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu594Arg/c.1781T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),1863,22,1898,"0,0115911486",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,75",Deleterious,1,Damaging,"29,64","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25467094,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu594Arg/c.1781T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2204,40,2255,"0,0177383592",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,75",Deleterious,1,Damaging,"29,66","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25467094,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu594Arg/c.1781T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),4243,56,4319,"0,0129659643",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,75",Deleterious,1,Damaging,"29,7","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,25467094,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu594Arg/c.1781T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2306,37,2350,"0,0157446809",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,75",Deleterious,1,Damaging,"29,77","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25467094,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu594Arg/c.1781T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),5523,74,5622,"0,0131625756",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,75",Deleterious,1,Damaging,"29,71","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25467094,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu594Arg/c.1781T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),5814,81,5927,"0,013666273",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,75",Deleterious,1,Damaging,"29,72","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25467094,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu594Arg/c.1781T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),3495,56,3570,"0,0156862745",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,75",Deleterious,1,Damaging,"29,89","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,25467094,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu594Arg/c.1781T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),1546,25,1579,"0,0158328056",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,75",Deleterious,1,Damaging,"29,55",14
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25467094,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu594Arg/c.1781T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),5664,77,5781,"0,0133194949",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,75",Deleterious,1,Damaging,"29,9","15,55"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25467094,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu594Arg/c.1781T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),4086,59,4162,"0,014175877",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,75",Deleterious,1,Damaging,"29,63","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25467094,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu594Arg/c.1781T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),3315,46,3376,"0,0136255924",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,75",Deleterious,1,Damaging,"29,55","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25467094,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu594Arg/c.1781T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),4356,69,4450,"0,015505618",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,75",Deleterious,1,Damaging,"29,65","15,54"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25467094,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu594Arg/c.1781T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2639,44,2696,"0,0163204748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,75",Deleterious,1,Damaging,"29,65",15
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25467094,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu594Arg/c.1781T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),4910,78,5009,"0,0155719705",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,75",Deleterious,1,Damaging,"29,84","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25467094,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu594Arg/c.1781T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),7503,114,7650,"0,0149019608",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,75",Deleterious,1,Damaging,"29,61","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25467094,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu594Arg/c.1781T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2463,44,2522,"0,0174464711",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,75",Deleterious,1,Damaging,"29,49","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25467094,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu594Arg/c.1781T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),5147,86,5251,"0,0163778328",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,75",Deleterious,1,Damaging,"29,61","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25467094,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu594Arg/c.1781T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),3750,61,3825,"0,0159477124",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,75",Deleterious,1,Damaging,"29,74","15,95"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,25467094,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu594Arg/c.1781T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2269,27,2308,"0,0116984402",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,75",Deleterious,1,Damaging,"29,68","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_086,2,25467094,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu594Arg/c.1781T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),1500,30,1544,"0,0194300518",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,75",Deleterious,1,Damaging,"29,74","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_087,2,25467094,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu594Arg/c.1781T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),4030,63,4119,"0,0152949745",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,75",Deleterious,1,Damaging,"29,63","14,4"
"low bq, low freq, many artifacts",UPN2_088,2,25467094,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu594Arg/c.1781T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2184,42,2245,"0,0187082405",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,75",Deleterious,1,Damaging,"29,89",14
"low bq, low freq, many artifacts",UPN2_085,2,25467099,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr592*/c.1776C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2269,26,2304,"0,0112847222",0,0,0,0,1,0,0,0,1,NO,NO,COSM231573,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,46","16,04"
"inspected, many artifacts",UPN2_053,2,25467099,G,T,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr592*/c.1776C>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|T),20468,289,20928,"0,0138092508",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,NA,NA,NA,NA,"30,82","28,65"
"low bq, low freq, many artifacts, many samples",UPN2_001,2,25467100,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr592Phe/c.1775A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),6941,72,7033,"0,010237452",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,338,Tolerated,31,"15,42"
"low bq, low freq, many artifacts, many samples",UPN2_041,2,25467100,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr592Phe/c.1775A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),34344,375,34893,"0,0107471413",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,338,Tolerated,"29,47","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,25467100,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr592Phe/c.1775A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),15791,167,16033,"0,010416017",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,338,Tolerated,"29,5","17,31"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,25467100,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr592Phe/c.1775A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),5065,78,5173,"0,0150782911",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,338,Tolerated,"29,34","19,71"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,25467100,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr592Phe/c.1775A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),19513,224,19820,"0,0113017154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,338,Tolerated,"29,47","18,99"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,25467100,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr592Phe/c.1775A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),19928,211,20224,"0,0104331487",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,338,Tolerated,"29,36","15,9"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,25467100,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr592Phe/c.1775A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),20183,212,20488,"0,0103475205",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,338,Tolerated,"29,36","16,46"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,25467100,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr592Phe/c.1775A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),15567,173,15804,"0,0109465958",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,338,Tolerated,"29,59","16,6"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,25467100,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr592Phe/c.1775A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),20582,226,20894,"0,0108165023",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,338,Tolerated,"29,48","16,87"
"low bq, low freq, many artifacts, many samples",UPN2_056,2,25467100,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr592Phe/c.1775A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),13850,142,14072,"0,0100909608",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,338,Tolerated,"29,49","17,06"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,25467100,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr592Phe/c.1775A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),17698,194,17965,"0,0107987754",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,338,Tolerated,"29,35","15,76"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,25467100,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr592Phe/c.1775A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),15804,188,16049,"0,0117141255",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,338,Tolerated,"29,45","16,23"
"low bq, low freq, many artifacts",UPN2_012,2,25467100,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr592Phe/c.1775A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),9807,126,9968,"0,0126404494",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,338,Tolerated,"30,75","22,92"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25467100,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr592Ser/c.1775A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),3615,41,3689,"0,0111141231",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,13",Deleterious,334,Tolerated,"29,11","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25467100,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr592Ser/c.1775A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),5135,57,5244,"0,0108695652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,13",Deleterious,334,Tolerated,"28,73","15,86"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25467103,G,C,missense_variant(MODERATE|MISSENSE|aCc/aGc|p.Thr591Ser/c.1772C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),4019,44,4074,"0,0108001964",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,762,Tolerated,"30,09","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25467103,G,C,missense_variant(MODERATE|MISSENSE|aCc/aGc|p.Thr591Ser/c.1772C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),3643,40,3687,"0,0108489287",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,762,Tolerated,"30,43",14
"low bq, low freq, many artifacts",UPN2_079,2,25467103,G,C,missense_variant(MODERATE|MISSENSE|aCc/aGc|p.Thr591Ser/c.1772C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2657,27,2689,"0,0100409074",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,762,Tolerated,"30,34",14
"low bq, low freq, many artifacts, many samples",UPN2_059,2,25467104,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr591Pro/c.1771A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),2438,35,2492,"0,0140449438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,08",Neutral,"0,2",Tolerated,"29,38","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25467104,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr591Pro/c.1771A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),4177,43,4243,"0,0101343389",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,08",Neutral,"0,2",Tolerated,"29,47","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25467104,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr591Pro/c.1771A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),3844,62,3926,"0,0157921549",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,08",Neutral,"0,2",Tolerated,"29,32","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25467104,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr591Pro/c.1771A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),3991,56,4072,"0,0137524558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,08",Neutral,"0,2",Tolerated,"29,3","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25467104,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr591Pro/c.1771A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),3906,53,3988,"0,0132898696",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,08",Neutral,"0,2",Tolerated,"29,38","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25467104,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr591Pro/c.1771A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),3621,42,3684,"0,0114006515",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,08",Neutral,"0,2",Tolerated,"29,43","15,48"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,25467104,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr591Pro/c.1771A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),1865,24,1892,"0,0126849894",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,08",Neutral,"0,2",Tolerated,"29,95","18,33"
"low bq, low freq, many artifacts, many samples",UPN2_067,2,25467104,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr591Pro/c.1771A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),1391,21,1420,"0,0147887324",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,08",Neutral,"0,2",Tolerated,"29,64","15,86"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25467104,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr591Pro/c.1771A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),2210,27,2246,"0,0120213713",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,08",Neutral,"0,2",Tolerated,"29,36","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25467104,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr591Pro/c.1771A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),4214,57,4302,"0,0132496513",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,08",Neutral,"0,2",Tolerated,"29,53","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,25467104,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr591Pro/c.1771A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),2313,29,2344,"0,0123720137",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,08",Neutral,"0,2",Tolerated,"29,36","16,86"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25467104,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr591Pro/c.1771A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),5501,66,5599,"0,0117878193",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,08",Neutral,"0,2",Tolerated,"29,66","15,39"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25467104,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr591Pro/c.1771A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),5792,73,5914,"0,0123435915",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,08",Neutral,"0,2",Tolerated,"29,38","15,25"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25467104,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr591Pro/c.1771A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),3498,38,3560,"0,0106741573",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,08",Neutral,"0,2",Tolerated,"29,52","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25467104,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr591Pro/c.1771A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),5658,70,5758,"0,012156999",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,08",Neutral,"0,2",Tolerated,"29,89","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25467104,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr591Pro/c.1771A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),4064,63,4142,"0,0152100435",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,08",Neutral,"0,2",Tolerated,"29,23","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25467104,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr591Pro/c.1771A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),3301,40,3361,"0,0119012199",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,08",Neutral,"0,2",Tolerated,"29,7","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25467104,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr591Pro/c.1771A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),2643,37,2689,"0,013759762",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,08",Neutral,"0,2",Tolerated,"29,64","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25467104,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr591Pro/c.1771A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),4907,73,5000,"0,0146",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,08",Neutral,"0,2",Tolerated,"29,49","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25467104,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr591Pro/c.1771A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),7464,111,7628,"0,0145516518",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,08",Neutral,"0,2",Tolerated,"29,39","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25467104,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr591Pro/c.1771A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),2464,33,2507,"0,0131631432",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,08",Neutral,"0,2",Tolerated,"29,62","15,45"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25467104,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr591Pro/c.1771A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),5120,72,5240,"0,013740458",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,08",Neutral,"0,2",Tolerated,"29,2","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25467104,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr591Pro/c.1771A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),3723,44,3811,"0,0115455261",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,08",Neutral,"0,2",Tolerated,"29,22","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_086,2,25467104,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr591Pro/c.1771A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),1506,24,1536,"0,015625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,08",Neutral,"0,2",Tolerated,"29,29","16,38"
"low bq, low freq, many artifacts, many samples",UPN2_087,2,25467104,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr591Pro/c.1771A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),4022,57,4100,"0,013902439",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,08",Neutral,"0,2",Tolerated,"29,53","16,12"
"low bq, low freq, many artifacts",UPN2_088,2,25467104,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr591Pro/c.1771A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),2201,31,2239,"0,0138454667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,08",Neutral,"0,2",Tolerated,"29,58","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_041,2,25467109,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys589Met/c.1766A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),34190,360,34659,"0,0103869125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,05",Neutral,8,Damaging,"30,6","16,66"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,25467109,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys589Met/c.1766A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),24110,260,24463,"0,0106282958",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,05",Neutral,8,Damaging,"30,64","16,77"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,25467109,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys589Met/c.1766A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),20021,224,20329,"0,0110187417",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,05",Neutral,8,Damaging,"30,55","18,21"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,25467109,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys589Met/c.1766A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),16581,195,16845,"0,0115761354",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,05",Neutral,8,Damaging,"30,47",17
"low bq, low freq, many artifacts",UPN2_057,2,25467109,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys589Met/c.1766A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),17606,183,17846,"0,0102543987",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,05",Neutral,8,Damaging,"30,55","16,73"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,25467110,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys589*/c.1765A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),15626,167,15867,"0,010524989",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,05","16,26"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,25467110,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys589*/c.1765A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),19715,214,20037,"0,0106802416",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,01","17,79"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,25467110,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys589*/c.1765A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),15408,159,15637,"0,0101681908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,13","16,65"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,25467110,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys589*/c.1765A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),12806,139,13025,"0,010671785",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,09","16,99"
"low bq, low freq, many artifacts",UPN2_056,2,25467110,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys589*/c.1765A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),13762,140,13948,"0,0100372813",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,18","17,53"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25467111,G,C,missense_variant(MODERATE|MISSENSE|caC/caG|p.His588Gln/c.1764C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),3851,42,3906,"0,0107526882",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,"0,36",Tolerated,"28,58","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25467111,G,C,missense_variant(MODERATE|MISSENSE|caC/caG|p.His588Gln/c.1764C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),3744,38,3782,"0,0100475939",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,"0,36",Tolerated,"28,52",15
"low bq, low freq, many artifacts, many samples",UPN2_088,2,25467111,G,C,missense_variant(MODERATE|MISSENSE|caC/caG|p.His588Gln/c.1764C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2197,23,2221,"0,0103556956",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,"0,36",Tolerated,"28,42",14
"low bq, low freq, many artifacts, many samples",UPN2_059,2,25467113,G,C,missense_variant(MODERATE|MISSENSE|Cac/Gac|p.His588Asp/c.1762C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2427,27,2461,"0,0109711499",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,335,Tolerated,"28,91",14
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25467113,G,C,missense_variant(MODERATE|MISSENSE|Cac/Gac|p.His588Asp/c.1762C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),4132,49,4189,"0,0116973025",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,335,Tolerated,"28,8","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25467113,G,C,missense_variant(MODERATE|MISSENSE|Cac/Gac|p.His588Asp/c.1762C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),5463,60,5534,"0,0108420672",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,335,Tolerated,"28,97","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25467113,G,C,missense_variant(MODERATE|MISSENSE|Cac/Gac|p.His588Asp/c.1762C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),5755,62,5844,"0,0106091718",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,335,Tolerated,"29,01","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25467113,G,C,missense_variant(MODERATE|MISSENSE|Cac/Gac|p.His588Asp/c.1762C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),3263,38,3310,"0,0114803625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,335,Tolerated,"29,21","14,18"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25467113,G,C,missense_variant(MODERATE|MISSENSE|Cac/Gac|p.His588Asp/c.1762C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),4324,50,4385,"0,0114025086",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,335,Tolerated,"29,01","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25467113,G,C,missense_variant(MODERATE|MISSENSE|Cac/Gac|p.His588Asp/c.1762C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2621,30,2656,"0,0112951807",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,335,Tolerated,"29,07",14
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25467113,G,C,missense_variant(MODERATE|MISSENSE|Cac/Gac|p.His588Asp/c.1762C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2434,34,2480,"0,0137096774",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,335,Tolerated,"28,82","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25467113,G,C,missense_variant(MODERATE|MISSENSE|Cac/Gac|p.His588Asp/c.1762C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),5089,66,5174,"0,0127560881",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,335,Tolerated,"29,04","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25467113,G,C,missense_variant(MODERATE|MISSENSE|Cac/Gac|p.His588Asp/c.1762C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),3695,51,3754,"0,0135855088",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,335,Tolerated,"29,04","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_087,2,25467113,G,C,missense_variant(MODERATE|MISSENSE|Cac/Gac|p.His588Asp/c.1762C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),4006,47,4067,"0,0115564298",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,335,Tolerated,"28,69","14,15"
"low bq, low freq, many artifacts",UPN2_088,2,25467113,G,C,missense_variant(MODERATE|MISSENSE|Cac/Gac|p.His588Asp/c.1762C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),2174,24,2203,"0,0108942351",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,335,Tolerated,"28,71","14,29"
"inspected, bad alignment, many artifacts",UPN2_044,2,25467118,C,A,missense_variant(MODERATE|MISSENSE|tGc/tTc|p.Cys586Phe/c.1757G>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),2581,30,2619,"0,0114547537",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,62",Deleterious,0,Damaging,"33,51","31,17"
"inspected, many artifacts",UPN2_058,2,25467121,AT,A,frameshift_variant(HIGH||atg/|p.Met585fs/c.1753delA|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),7990,107,8149,"0,0131304455",0,0,1,1,1,0,0,1,4,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,01",NA
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_059,2,25467130,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn582Thr/c.1745A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),1240,23,1271,"0,0180959874",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,169,Tolerated,"26,72","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25467130,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn582Thr/c.1745A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),2098,38,2148,"0,0176908752",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,169,Tolerated,"27,49","15,5"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,2,25467130,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn582Thr/c.1745A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),1945,42,1996,"0,0210420842",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,169,Tolerated,"26,51","15,69"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,2,25467130,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn582Thr/c.1745A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),2025,34,2069,"0,0164330594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,169,Tolerated,"26,73","14,97"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,2,25467130,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn582Thr/c.1745A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),1982,32,2025,"0,0158024691",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,169,Tolerated,"26,92","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25467130,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn582Thr/c.1745A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),1826,34,1869,"0,0181915463",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,169,Tolerated,"27,1","15,38"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_069,2,25467130,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn582Thr/c.1745A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),2133,39,2187,"0,0178326475",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,169,Tolerated,"26,9","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,25467130,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn582Thr/c.1745A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),1151,22,1187,"0,0185341196",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,169,Tolerated,"27,16","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25467130,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn582Thr/c.1745A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),2777,48,2841,"0,0168954593",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,169,Tolerated,"27,21",14
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25467130,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn582Thr/c.1745A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),2926,61,3000,"0,0203333333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,169,Tolerated,"27,16","15,9"
"low bq, many samples",UPN2_073,2,25467130,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn582Thr/c.1745A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),1752,41,1806,"0,0227021041",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,169,Tolerated,"27,41","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25467130,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn582Thr/c.1745A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),2865,44,2922,"0,0150581793",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,169,Tolerated,"27,9","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25467130,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn582Thr/c.1745A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),2041,44,2100,"0,020952381",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,169,Tolerated,"27,12","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25467130,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn582Thr/c.1745A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),1655,33,1704,"0,0193661972",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,169,Tolerated,"27,01","15,42"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25467130,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn582Thr/c.1745A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),2191,37,2246,"0,0164737311",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,169,Tolerated,"27,12","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25467130,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn582Thr/c.1745A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),1352,23,1380,"0,0166666667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,169,Tolerated,"27,53","15,26"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,2,25467130,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn582Thr/c.1745A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),2466,47,2526,"0,0186064925",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,169,Tolerated,"26,85","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25467130,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn582Thr/c.1745A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),3809,52,3878,"0,0134089737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,169,Tolerated,"27,29","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25467130,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn582Thr/c.1745A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),1246,21,1279,"0,0164190774",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,169,Tolerated,"27,16","15,9"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,2,25467130,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn582Thr/c.1745A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),2576,57,2656,"0,0214608434",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,169,Tolerated,"26,75","14,51"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,2,25467130,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn582Thr/c.1745A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),1903,21,1934,"0,0108583247",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,169,Tolerated,"26,7","14,62"
"low bq, bad alignment, low freq, many artifacts",UPN2_087,2,25467130,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn582Thr/c.1745A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),2035,32,2080,"0,0153846154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,169,Tolerated,"26,6","15,66"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25467131,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn582His/c.1744A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),2155,22,2189,"0,0100502513",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,108,Tolerated,"30,24",15
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25467131,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn582His/c.1744A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),2794,37,2841,"0,0130235832",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,108,Tolerated,"30,29",14
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25467131,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn582His/c.1744A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),2210,23,2246,"0,0102404274",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,108,Tolerated,"30,13","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25467131,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn582His/c.1744A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),2613,36,2656,"0,0135542169",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,108,Tolerated,"29,95","14,19"
"low bq, low freq, many artifacts",UPN2_087,2,25467131,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn582His/c.1744A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),2046,26,2080,"0,0125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,108,Tolerated,"30,21","14,27"
"low bq, low freq, many artifacts",UPN2_002,2,25467134,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp581Arg/c.1741T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|T),4586,48,4667,"0,0102849796",0,0,0,0,1,0,0,0,1,NO,NO,COSM231558,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-13,52",Deleterious,0,Damaging,"31,11","16,58"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_041,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),17225,387,17724,"0,0218348003",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,93","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_089,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),4831,85,4927,"0,0172518774",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"27,92","14,25"
"low bq, bad alignment, many samples",UPN2_042,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),12181,276,12510,"0,0220623501",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,76","14,81"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_043,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),7944,173,8154,"0,0212165808",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"26,06","14,54"
"low bq, bad alignment, many samples",UPN2_044,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),2530,80,2621,"0,0305227013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,54","14,75"
"low bq, bad alignment, many samples",UPN2_045,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),10940,262,11264,"0,0232599432",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,81","14,43"
"low bq, bad alignment, many samples",UPN2_046,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),9765,243,10070,"0,0241310824",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,93","14,71"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),16496,370,16944,"0,0218366383",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,99","14,84"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_048,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),15963,358,16384,"0,0218505859",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,77","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_006,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),3357,43,3411,"0,0126062738",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"28,05","14,81"
"low bq, bad alignment, many samples",UPN2_049,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),9998,227,10283,"0,0220752699",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,82","14,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),10155,219,10413,"0,0210314031",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,89","14,84"
"low bq, bad alignment, many samples",UPN2_051,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),7826,181,8041,"0,0225096381",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"26,13","14,72"
"low bq, bad alignment, many samples",UPN2_052,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),8347,190,8583,"0,022136782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,84","14,51"
"low bq, bad alignment, many samples",UPN2_053,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),10326,249,10626,"0,0234330887",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,86","14,96"
"low bq, bad alignment, many samples",UPN2_054,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),6465,174,6675,"0,0260674157",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,8","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_007,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),10317,108,10475,"0,0103102625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"28,44","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_008,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),15314,179,15563,"0,0115016385",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"27,76","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_009,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),12411,134,12608,"0,0106281726",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,28,"14,93"
"low bq, low freq, many artifacts, many samples",UPN2_011,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),9429,104,9565,"0,0108729744",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"28,01","14,52"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),11050,235,11359,"0,0206884409",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,78","14,77"
"low bq, bad alignment, many samples",UPN2_056,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),6956,167,7152,"0,0233501119",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,95","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_090,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),4651,86,4753,"0,0180938355",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"28,27","15,27"
"low bq, bad alignment, many samples",UPN2_057,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),8884,216,9146,"0,0236168817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,8","14,71"
"low bq, bad alignment, many samples",UPN2_058,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),7924,185,8158,"0,0226771267",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,94","14,23"
"low bq, bad alignment, many samples",UPN2_059,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),1187,84,1272,"0,0660377358",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"24,88","15,37"
"low bq, bad alignment, many samples",UPN2_060,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),2030,116,2156,"0,0538033395",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,56","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_013,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),2531,28,2567,"0,0109076743",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"28,11","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_091,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),4567,79,4660,"0,0169527897",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"28,22","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_092,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),3015,47,3071,"0,0153044611",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"28,19","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_093,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),3249,65,3323,"0,019560638",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"28,17","14,72"
"low bq, bad alignment, many samples",UPN2_061,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),1877,118,1997,"0,0590886329",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,14","15,08"
"low bq, bad alignment, many samples",UPN2_062,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),1939,127,2071,"0,0613230324",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,11","15,71"
"low bq, bad alignment, many samples",UPN2_063,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),1895,125,2025,"0,0617283951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,79","15,54"
"low bq, bad alignment, many samples",UPN2_064,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),1751,109,1869,"0,0583199572",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,18","15,38"
"low bq, bad alignment, many samples",UPN2_065,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),903,53,959,"0,055265902",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,73","16,11"
"low bq, bad alignment, many samples",UPN2_066,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),449,31,481,"0,0644490644",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,99","16,13"
"low bq, bad alignment, many samples",UPN2_067,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),690,32,724,"0,044198895",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,86","15,66"
"low bq, bad alignment, many samples",UPN2_068,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),1061,78,1141,"0,0683610868",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,18","14,77"
"low bq, bad alignment, many samples",UPN2_069,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),2041,142,2189,"0,0648698036",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,28","15,8"
"low bq, bad alignment, many samples",UPN2_070,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),1108,75,1187,"0,0631844987",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,59","15,13"
"low bq, bad alignment, many samples",UPN2_071,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),2660,159,2844,"0,055907173",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,72","15,62"
"low bq, bad alignment, many samples",UPN2_072,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),2814,178,3001,"0,0593135621",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,14","15,61"
"low bq, bad alignment, many samples",UPN2_073,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),1660,136,1806,"0,0753045404",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,61","15,16"
"low bq, bad alignment, many samples",UPN2_074,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),750,43,797,"0,0539523212",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,83","16,05"
"low bq, bad alignment, many samples",UPN2_075,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),2765,157,2930,"0,0535836177",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"26,08","15,77"
"low bq, bad alignment, many samples",UPN2_076,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),1968,125,2100,"0,0595238095",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"24,96","15,74"
"low bq, bad alignment, many samples",UPN2_077,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),1595,104,1704,"0,0610328638",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,39","15,68"
"low bq, bad alignment, many samples",UPN2_078,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),2112,131,2246,"0,0583259127",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,16","16,24"
"low bq, bad alignment, many samples",UPN2_079,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),1287,91,1380,"0,065942029",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,67","16,2"
"low bq, bad alignment, many samples",UPN2_080,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),2352,166,2526,"0,0657165479",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,56","15,22"
"low bq, bad alignment, many samples",UPN2_081,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),3649,205,3880,"0,0528350515",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,24","15,54"
"low bq, bad alignment, many samples",UPN2_082,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),1207,67,1279,"0,0523846755",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,36","15,18"
"low bq, bad alignment, many samples",UPN2_083,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),2465,185,2657,"0,0696273993",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,06","15,11"
"low bq, bad alignment, many samples",UPN2_084,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),1798,133,1934,"0,0687693899",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,15","15,69"
"low bq, bad alignment, many samples",UPN2_085,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),1093,73,1170,"0,0623931624",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,47","15,49"
"low bq, bad alignment, many samples",UPN2_086,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),737,42,781,"0,0537772087",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,24","16,79"
"low bq, bad alignment, many samples",UPN2_087,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),1940,132,2080,"0,0634615385",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,42","15,27"
"low bq, bad alignment, many samples",UPN2_088,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),1073,66,1140,"0,0578947368",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"25,84","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_094,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),5436,116,5573,"0,020814642",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"28,28","15,42"
"low bq, low freq, many artifacts, many samples",UPN2_095,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),4915,82,5009,"0,016370533",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"27,86","15,7"
"low bq, low freq, many artifacts, many samples",UPN2_096,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),5138,106,5254,"0,0201751047",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"28,12","15,81"
"low bq, low freq, many artifacts, many samples",UPN2_097,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),6197,122,6335,"0,01925809",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"27,97","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_098,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),5002,101,5120,"0,0197265625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"27,88","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_099,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),2522,33,2568,"0,0128504673",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"27,97","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_100,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),3630,60,3697,"0,0162293752",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"28,04","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_101,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),4377,71,4461,"0,015915714",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"27,93","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_102,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),4622,69,4703,"0,0146714863",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"28,07","15,58"
"low bq, low freq, many artifacts, many samples",UPN2_103,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),3992,74,4077,"0,0181506009",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"27,94","15,7"
"low bq, low freq, many artifacts, many samples",UPN2_104,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),5353,99,5467,"0,0181086519",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"28,13","15,84"
"low bq, low freq, many artifacts, many samples",UPN2_105,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),4366,69,4450,"0,015505618",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"28,12","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_106,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),6512,122,6654,"0,0183348362",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"27,99","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_107,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),8013,133,8164,"0,0162910338",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"28,2","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_108,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),6117,93,6219,"0,0149541727",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"28,27","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_109,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),5763,99,5880,"0,0168367347",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"27,94","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_110,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),6321,113,6462,"0,0174868462",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"28,03","14,9"
"low bq, low freq, many artifacts",UPN2_111,2,25467139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp579Ala/c.1736A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),5415,106,5543,"0,0191232185",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,43",Deleterious,26,Damaging,"27,98","15,19"
"not in 2nd Illumina, low freq, no database",UPN2_006,2,25467154,G,A,missense_variant(MODERATE|MISSENSE|gCa/gTa|p.Ala574Val/c.1721C>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|A),3365,42,3411,"0,0123131047",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,18",Neutral,"0,171",Tolerated,"34,98","34,4"
"inspected, many artifacts",UPN2_014,2,25467198,G,T,stop_gained(HIGH|NONSENSE|tgC/tgA|p.Cys559*/c.1677C>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|T),6886,80,6985,"0,0114531138",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,51","35,08"
"low freq, many artifacts",UPN2_006,2,25467199,CA,C,frameshift_variant(HIGH||tgc/|p.Cys559fs/c.1675delT|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|C),3361,42,3414,"0,0123022847",0,0,0,0,0,0,0,1,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,49",NA
"inspected, bad alignment, many artifacts",UPN2_044,2,25467202,A,G,missense_variant(MODERATE|MISSENSE|tTt/tCt|p.Phe558Ser/c.1673T>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|15|G),2583,31,2625,"0,0118095238",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,93",Deleterious,0,Damaging,"34,99","34,77"
"not in 2nd Illumina, low freq, no database",UPN2_006,2,25467409,C,A,missense_variant(MODERATE|MISSENSE|aGg/aTg|p.Arg556Met/c.1667G>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),2931,61,2993,"0,0203808887",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,0,Damaging,"35,06","32,75"
"low bq, low freq, many artifacts",UPN2_045,2,25467410,T,A,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg556Trp/c.1666A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),8612,92,8753,"0,0105106821",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,68",Deleterious,14,Damaging,"34,72","23,32"
"inspected, bad alignment, many artifacts",UPN2_041,2,25467416,A,G,missense_variant(MODERATE|MISSENSE|Tgc/Cgc|p.Cys554Arg/c.1660T>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),2218,24,2246,"0,0106856634",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-11,14",Deleterious,"0,001",Damaging,"35,27","35,83"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,25467418,T,A,missense_variant(MODERATE|MISSENSE|aAc/aTc|p.Asn553Ile/c.1658A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),9950,108,10086,"0,010707912",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,89",Deleterious,0,Damaging,"33,87","19,09"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,25467418,T,A,missense_variant(MODERATE|MISSENSE|aAc/aTc|p.Asn553Ile/c.1658A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),6604,82,6720,"0,012202381",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,89",Deleterious,0,Damaging,"33,95","17,77"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,25467418,T,A,missense_variant(MODERATE|MISSENSE|aAc/aTc|p.Asn553Ile/c.1658A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),8438,101,8569,"0,0117866729",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,89",Deleterious,0,Damaging,"33,77","20,26"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,25467418,T,A,missense_variant(MODERATE|MISSENSE|aAc/aTc|p.Asn553Ile/c.1658A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),6799,71,6886,"0,0103107755",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,89",Deleterious,0,Damaging,"33,85","17,37"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,25467418,T,A,missense_variant(MODERATE|MISSENSE|aAc/aTc|p.Asn553Ile/c.1658A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),7074,78,7179,"0,010865023",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,89",Deleterious,0,Damaging,"33,87","17,13"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,25467418,T,A,missense_variant(MODERATE|MISSENSE|aAc/aTc|p.Asn553Ile/c.1658A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),5022,58,5104,"0,0113636364",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,89",Deleterious,0,Damaging,"33,7","17,81"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,25467418,T,A,missense_variant(MODERATE|MISSENSE|aAc/aTc|p.Asn553Ile/c.1658A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),6819,74,6932,"0,0106751298",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,89",Deleterious,0,Damaging,"33,81","17,76"
"low bq, low freq, many artifacts",UPN2_058,2,25467418,T,A,missense_variant(MODERATE|MISSENSE|aAc/aTc|p.Asn553Ile/c.1658A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),8705,100,8830,"0,0113250283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,89",Deleterious,0,Damaging,"33,89","18,61"
"low bq, low freq, many artifacts, many samples",UPN2_041,2,25467419,T,A,missense_variant(MODERATE|MISSENSE|Aac/Tac|p.Asn553Tyr/c.1657A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),2214,26,2245,"0,0115812918",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,3,Damaging,"34,31","21,46"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,25467419,T,A,missense_variant(MODERATE|MISSENSE|Aac/Tac|p.Asn553Tyr/c.1657A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),9940,103,10086,"0,0102121753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,3,Damaging,"34,33","21,19"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,25467419,T,A,missense_variant(MODERATE|MISSENSE|Aac/Tac|p.Asn553Tyr/c.1657A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),6614,76,6720,"0,0113095238",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,3,Damaging,"34,32","22,96"
"low bq, low freq, many artifacts",UPN2_045,2,25467419,T,A,missense_variant(MODERATE|MISSENSE|Aac/Tac|p.Asn553Tyr/c.1657A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),8615,92,8750,"0,0105142857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,3,Damaging,"34,3","21,34"
"inspected, bad alignment, many artifacts",UPN2_041,2,25467421,T,A,missense_variant(MODERATE|MISSENSE|aAc/aTc|p.Asn552Ile/c.1655A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),2205,32,2245,"0,0142538976",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,"0,057",Tolerated,"34,17","25,69"
"low bq, low freq, many artifacts",UPN2_042,2,25467421,T,A,missense_variant(MODERATE|MISSENSE|aAc/aTc|p.Asn552Ile/c.1655A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),9941,103,10088,"0,0102101507",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,57,Tolerated,"34,12","21,11"
"low bq, low freq, many artifacts",UPN2_045,2,25467422,T,A,missense_variant(MODERATE|MISSENSE|Aac/Tac|p.Asn552Tyr/c.1654A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),8624,92,8749,"0,0105154875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,85",Deleterious,12,Damaging,"34,44","18,82"
"inspected, many artifacts",UPN2_056,2,25467433,A,G,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met548Thr/c.1643T>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),4421,59,4488,"0,0131461676",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,69",Deleterious,"0,023",Damaging,"34,8","34,24"
"low bq, low freq, many artifacts, many samples",UPN2_001,2,25467434,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met548Leu/c.1642A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),3646,44,3694,"0,0119112074",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,37",Neutral,1,Tolerated,"34,67",22
"low bq, low freq, many artifacts, many samples",UPN2_044,2,25467434,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met548Leu/c.1642A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),2760,36,2808,"0,0128205128",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,37",Neutral,1,Tolerated,"34,38","22,31"
"inspected, bad alignment, many artifacts",UPN2_041,2,25467437,G,A,missense_variant(MODERATE|MISSENSE|Ctc/Ttc|p.Leu547Phe/c.1639C>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),2204,29,2245,"0,0129175947",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,63",Deleterious,"0,087",Tolerated,"34,13","28,59"
"inspected, bad alignment, many artifacts",UPN2_044,2,25467437,G,A,missense_variant(MODERATE|MISSENSE|Ctc/Ttc|p.Leu547Phe/c.1639C>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),2733,57,2805,"0,0203208556",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,63",Deleterious,"0,087",Tolerated,"33,97","30,79"
"low bq, low freq, many artifacts, many samples",UPN2_056,2,25467442,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu545Val/c.1634A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),4412,54,4488,"0,0120320856",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,05",Deleterious,11,Damaging,"34,69","26,59"
"inspected, many artifacts",UPN2_057,2,25467447,GC,G,frameshift_variant(HIGH||ggc/|p.Gly543fs/c.1628delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),6830,77,6931,"0,011109508",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,86",NA
"inspected, many artifacts",UPN2_092,2,25467447,GC,G,frameshift_variant(HIGH||ggc/|p.Gly543fs/c.1628delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),2663,33,2700,"0,0122222222",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,14",NA
"inspected, bad alignment, many artifacts",UPN2_044,2,25467452,C,A,missense_variant(MODERATE|MISSENSE|Ggg/Tgg|p.Gly542Trp/c.1624G>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),2764,36,2803,"0,0128433821",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,56",Deleterious,"0,001",Damaging,"34,72","32,58"
"inspected, bad alignment, many artifacts",UPN2_044,2,25467458,A,G,missense_variant(MODERATE|MISSENSE|Tgc/Cgc|p.Cys540Arg/c.1618T>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),2760,32,2800,"0,0114285714",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-11,11",Deleterious,0,Damaging,"34,69","32,47"
"low bq, low freq, many artifacts, many samples",UPN2_001,2,25467461,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile539Phe/c.1615A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),3627,48,3690,"0,0130081301",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"33,48","18,08"
"low bq, low freq, many artifacts, many samples",UPN2_014,2,25467461,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile539Phe/c.1615A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),5103,63,5177,"0,01216921",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"34,04","19,17"
"low bq, low freq, many artifacts, many samples",UPN2_020,2,25467461,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile539Phe/c.1615A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),3210,39,3258,"0,0119705341",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"34,14","18,31"
"low bq, low freq, many artifacts, many samples",UPN2_022,2,25467461,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile539Phe/c.1615A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),4666,52,4732,"0,010989011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"34,01","21,12"
"low bq, low freq, many artifacts, many samples",UPN2_041,2,25467461,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile539Phe/c.1615A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),2201,26,2237,"0,011622709",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"33,34","17,23"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,25467461,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile539Phe/c.1615A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),9908,136,10067,"0,0135094864",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"33,16","18,54"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,25467461,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile539Phe/c.1615A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),6586,87,6703,"0,012979263",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"33,19","20,45"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,25467461,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile539Phe/c.1615A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),2765,28,2798,"0,010007148",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"33,12","18,18"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,25467461,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile539Phe/c.1615A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),8576,112,8727,"0,0128337344",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"33,2","17,35"
"low bq, low freq, many artifacts, many samples",UPN2_032,2,25467461,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile539Phe/c.1615A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),1888,23,1912,"0,0120292887",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"34,08","16,04"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,25467461,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile539Phe/c.1615A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),8346,105,8475,"0,0123893805",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"33,22","17,64"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,25467461,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile539Phe/c.1615A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),10773,148,10974,"0,0134864225",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"33,29","18,26"
"low bq, low freq, many artifacts, many samples",UPN2_048,2,25467461,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile539Phe/c.1615A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),7249,101,7389,"0,0136689674",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"33,34","18,2"
"low bq, low freq, many artifacts, many samples",UPN2_036,2,25467461,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile539Phe/c.1615A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),8712,93,8835,"0,0105263158",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"33,92","17,34"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,25467461,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile539Phe/c.1615A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),8403,118,8551,"0,0137995556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"33,16","18,58"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,25467461,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile539Phe/c.1615A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),7997,153,8192,"0,0186767578",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"33,21","20,53"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,25467461,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile539Phe/c.1615A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),6757,88,6878,"0,012794417",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"33,11","17,75"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,25467461,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile539Phe/c.1615A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),7044,84,7164,"0,0117252931",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"33,17","16,88"
"low bq, low freq, many artifacts, many samples",UPN2_039,2,25467461,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile539Phe/c.1615A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),8094,93,8216,"0,0113193768",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"33,96","19,16"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,25467461,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile539Phe/c.1615A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),8925,122,9084,"0,013430207",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"33,25","19,32"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,25467461,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile539Phe/c.1615A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),5004,68,5095,"0,0133464181",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"33,12","17,43"
"low bq, low freq, many artifacts, many samples",UPN2_007,2,25467461,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile539Phe/c.1615A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),10493,112,10630,"0,0105362183",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"33,57","17,5"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,25467461,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile539Phe/c.1615A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),8717,123,8876,"0,0138575935",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"33,27","17,76"
"low bq, low freq, many artifacts, many samples",UPN2_056,2,25467461,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile539Phe/c.1615A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),4395,68,4481,"0,0151751841",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"33,25","19,44"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,25467461,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile539Phe/c.1615A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),6801,84,6913,"0,0121510198",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"33,19","16,86"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,25467461,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile539Phe/c.1615A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),8697,106,8843,"0,0119868823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"33,19","18,04"
"low bq, low freq, many artifacts",UPN2_085,2,25467461,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile539Phe/c.1615A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),2191,31,2226,"0,0139263252",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"33,18","21,68"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25467463,G,C,missense_variant(MODERATE|MISSENSE|aCc/aGc|p.Thr538Ser/c.1613C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),4162,50,4218,"0,0118539592",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,26",Deleterious,111,Tolerated,"32,26","16,9"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25467463,G,C,missense_variant(MODERATE|MISSENSE|aCc/aGc|p.Thr538Ser/c.1613C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),3640,43,3696,"0,0116341991",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,26",Deleterious,111,Tolerated,"32,24","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,25467463,G,C,missense_variant(MODERATE|MISSENSE|aCc/aGc|p.Thr538Ser/c.1613C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),2428,27,2462,"0,0109666937",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,26",Deleterious,111,Tolerated,"32,26","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_066,2,25467463,G,C,missense_variant(MODERATE|MISSENSE|aCc/aGc|p.Thr538Ser/c.1613C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),1637,20,1660,"0,0120481928",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,26",Deleterious,111,Tolerated,"31,73",14
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25467463,G,C,missense_variant(MODERATE|MISSENSE|aCc/aGc|p.Thr538Ser/c.1613C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),3270,39,3321,"0,0117434508",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,26",Deleterious,111,Tolerated,"32,23",14
"low bq, low freq, many artifacts, many samples",UPN2_070,2,25467463,G,C,missense_variant(MODERATE|MISSENSE|aCc/aGc|p.Thr538Ser/c.1613C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),2423,26,2458,"0,0105777055",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,26",Deleterious,111,Tolerated,"32,32",14
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25467463,G,C,missense_variant(MODERATE|MISSENSE|aCc/aGc|p.Thr538Ser/c.1613C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),3075,46,3129,"0,0147011825",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,26",Deleterious,111,Tolerated,"31,98",14
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25467463,G,C,missense_variant(MODERATE|MISSENSE|aCc/aGc|p.Thr538Ser/c.1613C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),3839,39,3899,"0,0100025648",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,26",Deleterious,111,Tolerated,"32,21","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25467463,G,C,missense_variant(MODERATE|MISSENSE|aCc/aGc|p.Thr538Ser/c.1613C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),3920,48,3976,"0,0120724346",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,26",Deleterious,111,Tolerated,"32,27","15,83"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25467463,G,C,missense_variant(MODERATE|MISSENSE|aCc/aGc|p.Thr538Ser/c.1613C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),2484,34,2526,"0,0134600158",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,26",Deleterious,111,Tolerated,"32,22","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,25467463,G,C,missense_variant(MODERATE|MISSENSE|aCc/aGc|p.Thr538Ser/c.1613C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),2189,30,2225,"0,0134831461",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,26",Deleterious,111,Tolerated,"32,2",14
"low bq, low freq, many artifacts",UPN2_087,2,25467463,G,C,missense_variant(MODERATE|MISSENSE|aCc/aGc|p.Thr538Ser/c.1613C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),3403,38,3452,"0,0110081112",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,26",Deleterious,111,Tolerated,"32,21",14
"low bq, low freq, many artifacts, many samples",UPN2_041,2,25467464,T,A,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr538Ser/c.1612A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),2198,30,2237,"0,0134108181",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,26",Deleterious,111,Tolerated,"33,69","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,25467464,T,A,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr538Ser/c.1612A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),9892,114,10064,"0,011327504",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,26",Deleterious,111,Tolerated,"33,5","20,04"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,25467464,T,A,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr538Ser/c.1612A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),6581,76,6700,"0,0113432836",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,26",Deleterious,111,Tolerated,"33,61","15,83"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,25467464,T,A,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr538Ser/c.1612A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),2755,34,2798,"0,0121515368",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,26",Deleterious,111,Tolerated,"33,47","17,44"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,25467464,T,A,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr538Ser/c.1612A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),8583,95,8724,"0,0108895002",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,26",Deleterious,111,Tolerated,"33,54","16,52"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,25467464,T,A,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr538Ser/c.1612A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),8308,97,8468,"0,011454889",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,26",Deleterious,111,Tolerated,"33,42","17,59"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,25467464,T,A,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr538Ser/c.1612A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),10805,119,10971,"0,0108467779",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,26",Deleterious,111,Tolerated,"33,56","16,61"
"low bq, low freq, many artifacts, many samples",UPN2_048,2,25467464,T,A,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr538Ser/c.1612A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),7270,78,7385,"0,0105619499",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,26",Deleterious,111,Tolerated,"33,58","16,81"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,25467464,T,A,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr538Ser/c.1612A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),8391,104,8550,"0,0121637427",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,26",Deleterious,111,Tolerated,"33,54","16,45"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,25467464,T,A,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr538Ser/c.1612A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),8031,107,8187,"0,0130695004",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,26",Deleterious,111,Tolerated,"33,56","18,07"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,25467464,T,A,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr538Ser/c.1612A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),6762,79,6877,"0,0114875673",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,26",Deleterious,111,Tolerated,"33,54","18,33"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,25467464,T,A,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr538Ser/c.1612A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),7025,98,7159,"0,0136890627",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,26",Deleterious,111,Tolerated,"33,49","15,85"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,25467464,T,A,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr538Ser/c.1612A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),8943,102,9079,"0,0112347175",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,26",Deleterious,111,Tolerated,"33,67","16,68"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,25467464,T,A,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr538Ser/c.1612A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),4987,77,5091,"0,0151247299",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,26",Deleterious,111,Tolerated,"33,53","19,19"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,25467464,T,A,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr538Ser/c.1612A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),8727,104,8870,"0,0117249154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,26",Deleterious,111,Tolerated,"33,55","18,27"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,25467464,T,A,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr538Ser/c.1612A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),6790,87,6910,"0,0125904486",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,26",Deleterious,111,Tolerated,"33,48","16,67"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,25467464,T,A,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr538Ser/c.1612A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),8698,107,8838,"0,0121068115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,26",Deleterious,111,Tolerated,"33,61","16,73"
"low bq, low freq, many artifacts",UPN2_071,2,25467464,T,A,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr538Ser/c.1612A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),3078,33,3128,"0,0105498721",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,26",Deleterious,111,Tolerated,"33,6","16,67"
"low bq, low freq, many artifacts",UPN2_060,2,25467468,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr536*/c.1608C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),3444,36,3485,"0,0103299857",0,0,0,0,1,0,0,0,1,"0,0116",NO,NO,NO,O,NO,rs370376334,NO,NO,NO,NO,NA,NA,NA,NA,"33,15","21,08"
"low bq, low freq, many artifacts, many samples",UPN2_041,2,25467469,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr536Phe/c.1607A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),2188,24,2235,"0,010738255",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,25,Damaging,"33,54","15,75"
"low bq, low freq, many artifacts, many samples",UPN2_024,2,25467469,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr536Phe/c.1607A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),2469,26,2499,"0,0104041617",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,25,Damaging,"34,22","15,54"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,25467469,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr536Phe/c.1607A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),6599,80,6699,"0,0119420809",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,25,Damaging,"33,61","16,29"
"low bq, low freq, many artifacts, many samples",UPN2_006,2,25467469,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr536Phe/c.1607A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),2886,45,2939,"0,0153113304",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,25,Damaging,"33,91","23,89"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,25467469,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr536Phe/c.1607A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),8959,93,9075,"0,0102479339",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,25,Damaging,"33,52","19,45"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,25467469,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr536Phe/c.1607A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),8748,92,8866,"0,0103767201",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,25,Damaging,"33,38","17,01"
"low bq, low freq, many artifacts, many samples",UPN2_056,2,25467469,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr536Phe/c.1607A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),4417,51,4478,"0,011389013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,25,Damaging,"33,46","15,49"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,25467469,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr536Phe/c.1607A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),8719,96,8837,"0,0108634152",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,25,Damaging,"33,56","18,95"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25467469,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr536Phe/c.1607A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),3277,37,3320,"0,0111445783",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,25,Damaging,"33,4","15,89"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25467469,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr536Phe/c.1607A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),3084,32,3128,"0,010230179",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,25,Damaging,"33,27","15,25"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25467469,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr536Phe/c.1607A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),2282,25,2322,"0,0107665805",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,25,Damaging,"33,31","16,28"
"low bq, low freq, many artifacts",UPN2_088,2,25467469,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr536Phe/c.1607A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),2723,29,2762,"0,0104996379",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,25,Damaging,"33,44","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_041,2,25467475,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln534Leu/c.1601A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),2209,23,2241,"0,0102632753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,52",Deleterious,3,Damaging,"33,75","22,26"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,25467475,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln534Leu/c.1601A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),8612,94,8746,"0,0107477704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,52",Deleterious,3,Damaging,"33,73","19,72"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,25467475,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln534Leu/c.1601A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),10789,144,10983,"0,0131111718",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,52",Deleterious,3,Damaging,"33,63","20,23"
"low bq, low freq, many artifacts, many samples",UPN2_048,2,25467475,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln534Leu/c.1601A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),7281,81,7395,"0,0109533469",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,52",Deleterious,3,Damaging,"33,83","19,11"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,25467475,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln534Leu/c.1601A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),8442,93,8562,"0,0108619481",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,52",Deleterious,3,Damaging,"33,63","19,01"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,25467475,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln534Leu/c.1601A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),8057,93,8188,"0,011358085",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,52",Deleterious,3,Damaging,"33,51","19,82"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,25467475,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln534Leu/c.1601A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),5018,60,5106,"0,0117508813",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,52",Deleterious,3,Damaging,"33,62","18,83"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,25467475,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln534Leu/c.1601A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),8750,113,8900,"0,0126966292",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,52",Deleterious,3,Damaging,"33,68","19,53"
"low bq, low freq, many artifacts, many samples",UPN2_056,2,25467475,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln534Leu/c.1601A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),4414,58,4485,"0,0129319955",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,52",Deleterious,3,Damaging,"33,61","19,14"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,25467475,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln534Leu/c.1601A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),6813,78,6926,"0,0112619116",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,52",Deleterious,3,Damaging,"33,51","20,47"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,25467475,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln534Leu/c.1601A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),2319,26,2356,"0,0110356537",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,52",Deleterious,3,Damaging,"33,42","19,27"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25467475,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln534Leu/c.1601A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),3433,37,3488,"0,0106077982",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,52",Deleterious,3,Damaging,"33,32","20,62"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25467475,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln534Leu/c.1601A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),3276,36,3330,"0,0108108108",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,52",Deleterious,3,Damaging,"33,3","18,92"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25467475,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln534Leu/c.1601A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),6370,65,6456,"0,0100681537",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,52",Deleterious,3,Damaging,"33,5","19,49"
"low bq, low freq, many artifacts",UPN2_085,2,25467475,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln534Leu/c.1601A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|A),2183,26,2221,"0,0117064385",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,52",Deleterious,3,Damaging,"33,67","17,23"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25467476,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln534Glu/c.1600C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),3087,33,3136,"0,0105229592",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,79",Deleterious,19,Damaging,"32,3","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25467476,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln534Glu/c.1600C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),3862,40,3917,"0,0102118969",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,79",Deleterious,19,Damaging,"32,48","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25467476,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln534Glu/c.1600C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),3952,42,4007,"0,0104816571",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,79",Deleterious,19,Damaging,"32,48","14,62"
"low bq, low freq, many artifacts",UPN2_085,2,25467476,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln534Glu/c.1600C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),2183,28,2224,"0,0125899281",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,79",Deleterious,19,Damaging,"32,47","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25467477,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr533*/c.1599C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),3767,40,3811,"0,0104959328",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,NA,NA,NA,NA,"32,35","15,75"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,25467477,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr533*/c.1599C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),2247,26,2289,"0,0113586719",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,NA,NA,NA,NA,"32,06","16,19"
"low bq, many samples",UPN2_059,2,25467478,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr533Ser/c.1598A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),4561,121,4741,"0,0255220418",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,64,Tolerated,"28,79","16,09"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25467478,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr533Ser/c.1598A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),6770,145,6953,"0,0208543075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,64,Tolerated,"28,77","16,33"
"low bq, many samples",UPN2_061,2,25467478,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr533Ser/c.1598A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),8207,207,8449,"0,0244999408",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,64,Tolerated,"28,76","17,36"
"low bq, many samples",UPN2_062,2,25467478,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr533Ser/c.1598A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),7739,202,7984,"0,0253006012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,64,Tolerated,"28,6","16,43"
"low bq, many samples",UPN2_063,2,25467478,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr533Ser/c.1598A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),6352,168,6565,"0,0255902513",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,64,Tolerated,"28,61","16,2"
"low bq, many samples",UPN2_064,2,25467478,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr533Ser/c.1598A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),7176,194,7402,"0,0262091327",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,64,Tolerated,"28,89","16,49"
"low bq, many samples",UPN2_065,2,25467478,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr533Ser/c.1598A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),4807,128,4950,"0,0258585859",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,64,Tolerated,"28,72","15,88"
"low bq, many samples",UPN2_066,2,25467478,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr533Ser/c.1598A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),3226,82,3323,"0,0246764971",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,64,Tolerated,"28,55","15,96"
"low bq, many samples",UPN2_067,2,25467478,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr533Ser/c.1598A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),3371,91,3482,"0,0261344055",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,64,Tolerated,"28,79","17,41"
"low bq, many samples",UPN2_068,2,25467478,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr533Ser/c.1598A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),3967,116,4108,"0,0282375852",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,64,Tolerated,"28,49","17,26"
"low bq, many samples",UPN2_069,2,25467478,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr533Ser/c.1598A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),6438,195,6658,"0,0292880745",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,64,Tolerated,"28,74","16,44"
"low bq, many samples",UPN2_070,2,25467478,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr533Ser/c.1598A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),4775,139,4948,"0,0280921584",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,64,Tolerated,"28,61","16,61"
"low bq, many samples",UPN2_071,2,25467478,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr533Ser/c.1598A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),6050,151,6255,"0,0241406875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,64,Tolerated,"28,53","16,28"
"low bq, many samples",UPN2_072,2,25467478,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr533Ser/c.1598A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),7573,224,7832,"0,0286006129",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,64,Tolerated,"28,67","15,85"
"low bq, many samples",UPN2_073,2,25467478,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr533Ser/c.1598A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),6998,169,7200,"0,0234722222",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,64,Tolerated,"28,72","17,34"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,25467478,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr533Ser/c.1598A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),3147,70,3237,"0,0216249614",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,64,Tolerated,"28,84","15,87"
"low bq, many samples",UPN2_075,2,25467478,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr533Ser/c.1598A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),9362,234,9644,"0,024263791",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,64,Tolerated,"28,94","16,06"
"low bq, many samples",UPN2_076,2,25467478,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr533Ser/c.1598A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),6008,176,6215,"0,0283185841",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,64,Tolerated,"28,82","16,05"
"low bq, many samples",UPN2_077,2,25467478,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr533Ser/c.1598A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),6737,205,6976,"0,0293864679",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,64,Tolerated,"28,87","16,78"
"low bq, many samples",UPN2_078,2,25467478,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr533Ser/c.1598A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),8756,268,9067,"0,0295577368",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,64,Tolerated,"28,81","16,82"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25467478,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr533Ser/c.1598A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),4522,100,4650,"0,0215053763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,64,Tolerated,"28,94","16,72"
"low bq, many samples",UPN2_080,2,25467478,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr533Ser/c.1598A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),7707,198,7958,"0,0248806233",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,64,Tolerated,"28,85","16,52"
"low bq, many samples",UPN2_081,2,25467478,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr533Ser/c.1598A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),12542,339,12948,"0,0261816497",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,64,Tolerated,"28,83","17,06"
"low bq, many samples",UPN2_082,2,25467478,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr533Ser/c.1598A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),4933,117,5079,"0,0230360307",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,64,Tolerated,"28,83","16,21"
"low bq, many samples",UPN2_083,2,25467478,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr533Ser/c.1598A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),7242,203,7507,"0,027041428",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,64,Tolerated,"28,65","16,63"
"low bq, many samples",UPN2_084,2,25467478,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr533Ser/c.1598A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),7102,217,7357,"0,0294957184",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,64,Tolerated,"28,64","16,18"
"low bq, many samples",UPN2_085,2,25467478,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr533Ser/c.1598A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),4317,118,4466,"0,026421854",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,64,Tolerated,"28,6","16,57"
"low bq, many samples",UPN2_086,2,25467478,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr533Ser/c.1598A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),2561,78,2650,"0,0294339623",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,64,Tolerated,"28,99","16,62"
"low bq, many samples",UPN2_087,2,25467478,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr533Ser/c.1598A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),6691,182,6929,"0,0262664165",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,64,Tolerated,"28,83","15,91"
low bq,UPN2_088,2,25467478,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr533Ser/c.1598A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),5374,124,5528,"0,022431259",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,64,Tolerated,"29,02","16,27"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,25467484,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp531Ala/c.1592A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),4650,49,4730,"0,010359408",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,25",Deleterious,1,Damaging,"30,28","15,88"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25467484,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp531Ala/c.1592A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),6826,81,6980,"0,0116045845",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,25",Deleterious,1,Damaging,"30,27","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25467484,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp531Ala/c.1592A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),8281,117,8468,"0,0138167218",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,25",Deleterious,1,Damaging,"30,33","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25467484,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp531Ala/c.1592A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),7829,90,7962,"0,0113036925",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,25",Deleterious,1,Damaging,"30,15","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25467484,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp531Ala/c.1592A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),7233,80,7389,"0,0108269049",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,25",Deleterious,1,Damaging,"30,31","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,25467484,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp531Ala/c.1592A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),4847,59,4949,"0,0119216003",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,25",Deleterious,1,Damaging,"30,31","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25467484,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp531Ala/c.1592A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),4036,47,4108,"0,0114410906",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,25",Deleterious,1,Damaging,"30,21","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25467484,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp531Ala/c.1592A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),6515,85,6654,"0,0127742711",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,25",Deleterious,1,Damaging,"30,27","16,42"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,25467484,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp531Ala/c.1592A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),4811,62,4926,"0,0125862769",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,25",Deleterious,1,Damaging,"30,21","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25467484,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp531Ala/c.1592A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),6130,71,6253,"0,0113545498",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,25",Deleterious,1,Damaging,"30,26","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25467484,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp531Ala/c.1592A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),7705,84,7843,"0,0107101874",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,25",Deleterious,1,Damaging,"30,33","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25467484,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp531Ala/c.1592A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),7064,83,7208,"0,0115149834",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,25",Deleterious,1,Damaging,"30,4","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,25467484,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp531Ala/c.1592A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),3186,41,3254,"0,0125998771",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,25",Deleterious,1,Damaging,"30,5","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25467484,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp531Ala/c.1592A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),9479,108,9663,"0,0111766532",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,25",Deleterious,1,Damaging,"30,33","15,42"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25467484,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp531Ala/c.1592A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),6066,65,6182,"0,0105143966",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,25",Deleterious,1,Damaging,"30,18","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25467484,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp531Ala/c.1592A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),6859,86,6981,"0,012319152",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,25",Deleterious,1,Damaging,"30,15","16,24"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25467484,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp531Ala/c.1592A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),8882,111,9058,"0,0122543608",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,25",Deleterious,1,Damaging,"30,3","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25467484,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp531Ala/c.1592A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),4545,53,4648,"0,0114027539",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,25",Deleterious,1,Damaging,"30,32","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25467484,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp531Ala/c.1592A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),7784,85,7956,"0,0106837607",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,25",Deleterious,1,Damaging,"30,22","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25467484,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp531Ala/c.1592A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),7382,85,7514,"0,0113122172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,25",Deleterious,1,Damaging,"30,19","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25467484,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp531Ala/c.1592A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),7233,81,7368,"0,0109934853",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,25",Deleterious,1,Damaging,"30,25","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,25467484,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp531Ala/c.1592A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),4370,49,4460,"0,0109865471",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,25",Deleterious,1,Damaging,"30,1",14
"low bq, low freq, many artifacts, many samples",UPN2_086,2,25467484,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp531Ala/c.1592A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),2618,35,2675,"0,0130841121",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,25",Deleterious,1,Damaging,"30,16","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_087,2,25467484,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp531Ala/c.1592A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),6802,85,6928,"0,0122690531",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,25",Deleterious,1,Damaging,"30,24","15,76"
"low bq, low freq, many artifacts",UPN2_088,2,25467484,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp531Ala/c.1592A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),5412,68,5527,"0,0123032386",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,25",Deleterious,1,Damaging,"30,36","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25467487,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp530Ala/c.1589A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),8378,91,8506,"0,0106983306",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,28,Damaging,"31,16","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25467487,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp530Ala/c.1589A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),7320,79,7445,"0,0106111484",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,28,Damaging,"31,25","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25467487,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp530Ala/c.1589A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),4078,43,4142,"0,0103814582",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,28,Damaging,"31,1","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,25467487,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp530Ala/c.1589A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),4415,46,4486,"0,0102541239",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,28,Damaging,"31,02","14,67"
"low bq, low freq, many artifacts",UPN2_086,2,25467487,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp530Ala/c.1589A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|G),2633,30,2681,"0,0111898545",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,28,Damaging,"31,32","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,25467504,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys524Trp/c.1572T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),4694,51,4756,"0,0107232969",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,31",Deleterious,45,Damaging,"30,8","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25467504,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys524Trp/c.1572T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),8363,94,8496,"0,0110640301",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,31",Deleterious,45,Damaging,"30,95","15,39"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25467504,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys524Trp/c.1572T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),6470,74,6583,"0,0112410755",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,31",Deleterious,45,Damaging,"30,97","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,25467504,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys524Trp/c.1572T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),4877,56,4973,"0,0112608084",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,31",Deleterious,45,Damaging,"31,07","15,48"
"low bq, low freq, many artifacts, many samples",UPN2_066,2,25467504,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys524Trp/c.1572T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),3299,42,3354,"0,0125223614",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,31",Deleterious,45,Damaging,"30,63","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_067,2,25467504,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys524Trp/c.1572T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),3435,37,3494,"0,0105895821",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,31",Deleterious,45,Damaging,31,"14,54"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25467504,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys524Trp/c.1572T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),4058,47,4131,"0,0113773905",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,31",Deleterious,45,Damaging,"30,91","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25467504,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys524Trp/c.1572T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),6567,69,6687,"0,0103185285",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,31",Deleterious,45,Damaging,"30,79","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25467504,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys524Trp/c.1572T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),7137,75,7243,"0,0103548253",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,31",Deleterious,45,Damaging,"30,99","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25467504,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys524Trp/c.1572T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),9568,105,9714,"0,0108091414",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,31",Deleterious,45,Damaging,"31,02","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25467504,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys524Trp/c.1572T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),8985,92,9125,"0,0100821918",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,31",Deleterious,45,Damaging,"30,76","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25467504,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys524Trp/c.1572T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),7852,89,8004,"0,0111194403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,31",Deleterious,45,Damaging,"30,9","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25467504,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys524Trp/c.1572T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),7393,94,7535,"0,0124751161",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,31",Deleterious,45,Damaging,"31,02","14,33"
"low bq, low freq, many artifacts",UPN2_088,2,25467504,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys524Trp/c.1572T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),5483,61,5571,"0,0109495602",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,31",Deleterious,45,Damaging,"31,07","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_066,2,25467506,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys524Gly/c.1570T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),3276,48,3354,"0,0143112701",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,54",Deleterious,34,Damaging,"30,27","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_067,2,25467506,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys524Gly/c.1570T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),3432,38,3493,"0,0108789007",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,54",Deleterious,34,Damaging,"30,52","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25467506,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys524Gly/c.1570T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),4067,47,4136,"0,0113636364",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,54",Deleterious,34,Damaging,"30,41","15,87"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25467506,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys524Gly/c.1570T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),6578,72,6686,"0,0107687706",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,54",Deleterious,34,Damaging,"30,38","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25467506,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys524Gly/c.1570T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),7112,81,7242,"0,0111847556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,54",Deleterious,34,Damaging,"30,36","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,25467506,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys524Gly/c.1570T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),3222,37,3283,"0,0112701797",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,54",Deleterious,34,Damaging,"30,66","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25467506,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys524Gly/c.1570T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),6887,79,7009,"0,0112712227",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,54",Deleterious,34,Damaging,"30,49","15,54"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25467506,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys524Gly/c.1570T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),5023,58,5099,"0,0113747794",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,54",Deleterious,34,Damaging,"30,41","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,25467506,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys524Gly/c.1570T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),4410,49,4477,"0,0109448291",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,54",Deleterious,34,Damaging,"30,47","15,18"
"low bq, low freq, many artifacts",UPN2_088,2,25467506,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys524Gly/c.1570T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|14|C),5487,58,5571,"0,0104110573",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,54",Deleterious,34,Damaging,"30,59","14,76"
inspected,UPN2_046,2,25468133,G,A,stop_gained(HIGH|NONSENSE|Caa/Taa|p.Gln515*/c.1543C>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|13|A),10211,348,10622,"0,0327621917",0,0,0,0,1,0,0,1,2,NO,NO,COSM1318927,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,87","35,4"
"not in 2nd Illumina, low freq, no database",UPN2_006,2,25468184,C,T,missense_variant(MODERATE|MISSENSE|Ggg/Agg|p.Gly498Arg/c.1492G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|13|T),2600,45,2647,"0,0170003778",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,21",Deleterious,"0,01",Damaging,"34,36","32,87"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25468192,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile495Ser/c.1484T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|13|C),2615,33,2664,"0,0123873874",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,1,Damaging,"30,88","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25468192,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile495Ser/c.1484T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|13|C),1689,20,1714,"0,0116686114",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,1,Damaging,"30,58","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25468192,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile495Ser/c.1484T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|13|C),2541,29,2584,"0,0112229102",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,1,Damaging,"30,94","16,34"
"not in 2nd Illumina, low freq, no database",UPN2_006,2,25468196,A,G,missense_variant(MODERATE|MISSENSE|Tgc/Cgc|p.Cys494Arg/c.1480T>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|13|G),5073,58,5190,"0,0111753372",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,28",Deleterious,0,Damaging,"31,85","32,97"
"low bq, low freq, many artifacts, many samples",UPN2_001,2,25468196,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys494Ser/c.1480T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|13|T),6325,70,6419,"0,0109051254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,77",Deleterious,1,Damaging,"31,75","16,34"
"low bq, low freq, many artifacts, many samples",UPN2_041,2,25468196,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys494Ser/c.1480T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|13|T),39685,518,40503,"0,0127891761",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,77",Deleterious,1,Damaging,"31,46","18,91"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,25468196,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys494Ser/c.1480T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|13|T),21304,251,21685,"0,0115748213",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,77",Deleterious,1,Damaging,"31,53","19,35"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,25468196,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys494Ser/c.1480T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|13|T),3928,44,3996,"0,011011011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,77",Deleterious,1,Damaging,"31,57","18,77"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,25468196,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys494Ser/c.1480T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|13|T),13789,142,14007,"0,0101377882",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,77",Deleterious,1,Damaging,"31,55","18,03"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,25468196,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys494Ser/c.1480T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|13|T),20348,245,20714,"0,0118277493",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,77",Deleterious,1,Damaging,"31,58","18,76"
"low bq, low freq, many artifacts, many samples",UPN2_034,2,25468196,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys494Ser/c.1480T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|13|T),3595,41,3653,"0,0112236518",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,77",Deleterious,1,Damaging,"32,14","20,12"
"low bq, low freq, many artifacts, many samples",UPN2_048,2,25468196,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys494Ser/c.1480T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|13|T),29506,371,30023,"0,0123571928",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,77",Deleterious,1,Damaging,"31,44","19,53"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,25468196,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys494Ser/c.1480T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|13|T),17118,199,17459,"0,0113981328",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,77",Deleterious,1,Damaging,"31,43","20,12"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,25468196,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys494Ser/c.1480T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|13|T),15998,199,16341,"0,0121779573",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,77",Deleterious,1,Damaging,"31,51","19,34"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,25468196,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys494Ser/c.1480T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|13|T),17836,200,18140,"0,0110253583",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,77",Deleterious,1,Damaging,"31,39",19
"low bq, low freq, many artifacts, many samples",UPN2_052,2,25468196,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys494Ser/c.1480T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|13|T),14771,180,15030,"0,0119760479",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,77",Deleterious,1,Damaging,"31,58","19,71"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,25468196,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys494Ser/c.1480T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|13|T),18413,219,18733,"0,0116905995",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,77",Deleterious,1,Damaging,"31,52","19,32"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,25468196,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys494Ser/c.1480T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|13|T),13549,164,13792,"0,0118909513",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,77",Deleterious,1,Damaging,"31,63","17,63"
"low bq, low freq, many artifacts, many samples",UPN2_007,2,25468196,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys494Ser/c.1480T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|13|T),16910,182,17169,"0,0106005009",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,77",Deleterious,1,Damaging,"31,87","17,43"
"low bq, low freq, many artifacts, many samples",UPN2_008,2,25468196,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys494Ser/c.1480T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|13|T),23007,264,23382,"0,0112907365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,77",Deleterious,1,Damaging,"31,89","19,12"
"low bq, low freq, many artifacts, many samples",UPN2_009,2,25468196,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys494Ser/c.1480T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|13|T),18896,206,19172,"0,0107448362",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,77",Deleterious,1,Damaging,"31,8","16,35"
"low bq, low freq, many artifacts, many samples",UPN2_010,2,25468196,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys494Ser/c.1480T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|13|T),14275,159,14498,"0,0109670299",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,77",Deleterious,1,Damaging,"31,87","18,47"
"low bq, low freq, many artifacts, many samples",UPN2_011,2,25468196,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys494Ser/c.1480T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|13|T),15065,158,15295,"0,0103301733",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,77",Deleterious,1,Damaging,"31,92","16,75"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,25468196,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys494Ser/c.1480T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|13|T),18353,204,18693,"0,0109131761",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,77",Deleterious,1,Damaging,"31,5","18,35"
"low bq, low freq, many artifacts, many samples",UPN2_056,2,25468196,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys494Ser/c.1480T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|13|T),12440,153,12639,"0,0121053881",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,77",Deleterious,1,Damaging,"31,47","18,54"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,25468196,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys494Ser/c.1480T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|13|T),14316,172,14560,"0,0118131868",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,77",Deleterious,1,Damaging,"31,45","19,8"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,25468196,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys494Ser/c.1480T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|13|T),17841,195,18148,"0,0107449857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,77",Deleterious,1,Damaging,"31,42","18,41"
"low bq, low freq, many artifacts, many samples",UPN2_013,2,25468196,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys494Ser/c.1480T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|13|T),4854,54,4943,"0,0109245398",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,77",Deleterious,1,Damaging,"31,8","16,52"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25468196,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys494Ser/c.1480T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|13|T),1971,24,2000,"0,012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,77",Deleterious,1,Damaging,"31,52","14,54"
"low bq, low freq, many artifacts",UPN2_085,2,25468196,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys494Ser/c.1480T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|13|T),2167,23,2202,"0,01044505",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,77",Deleterious,1,Damaging,"31,93","16,87"
"inspected, bad alignment, many artifacts",UPN2_044,2,25468895,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile490Phe/c.1468A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|12|A),1353,31,1389,"0,0223182145",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,39",Neutral,"0,11",Tolerated,"35,59","34,58"
"not in 2nd Illumina, low freq, no database",UPN2_006,2,25468924,A,G,missense_variant(MODERATE|MISSENSE|gTg/gCg|p.Val480Ala/c.1439T>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|12|G),2050,38,2115,"0,0179669031",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,23",Neutral,"0,353",Tolerated,"32,74","35,68"
"low freq, many artifacts",UPN2_006,2,25468924,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val480Glu/c.1439T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|12|T),2050,27,2115,"0,0127659574",0,0,0,0,0,0,0,1,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,02",Deleterious,81,Tolerated,"32,74",36
"inspected, many artifacts, low freq",UPN2_048,2,25468931,G,A,missense_variant(MODERATE|MISSENSE|Cgg/Tgg|p.Arg478Trp/c.1432C>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|12|A),9365,97,9470,"0,0102428722",0,0,0,0,1,0,0,1,2,NO,NO,COSM87003,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NA,NO,NO,"-4,95",Deleterious,"0,001",Damaging,"34,58","33,08"
"low freq, many artifacts, many samples",UPN2_001,2,25469031,C,G,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),5937,105,6057,"0,0173353145",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,3,Damaging,"33,31","30,97"
"low freq, many artifacts, many samples",UPN2_014,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),11964,218,12208,"0,0178571429",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,3,Damaging,33,"31,17"
"inspected, strandbias, bad alignment",UPN2_015,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),16009,171,16223,"0,0105405905",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,"0,003",Damaging,"32,97","31,13"
"inspected, strandbias, bad alignment",UPN2_016,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),7865,96,7980,"0,0120300752",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,"0,003",Damaging,"33,05","30,69"
"low freq, many artifacts, many samples",UPN2_017,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),5361,103,5470,"0,0188299817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,3,Damaging,"32,78","30,91"
"inspected, strandbias, bad alignment",UPN2_018,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),8602,119,8746,"0,01360622",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,"0,003",Damaging,"33,02","31,14"
"low freq, many artifacts, many samples",UPN2_019,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),8874,139,9036,"0,0153829128",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,3,Damaging,"33,04","31,32"
"low freq, many artifacts, many samples",UPN2_020,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),7902,140,8058,"0,0173740382",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,3,Damaging,"32,88","30,96"
"low freq, many artifacts, many samples",UPN2_021,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),9387,159,9559,"0,0166335391",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,3,Damaging,"33,04","31,46"
"low freq, many artifacts, many samples",UPN2_002,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),7545,109,7663,"0,0142241942",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,3,Damaging,"33,29","30,97"
"inspected, strandbias, bad alignment",UPN2_003,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),1550,25,1576,"0,0158629442",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,"0,003",Damaging,"33,44","30,12"
"low freq, many artifacts, many samples",UPN2_022,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),10913,122,11054,"0,0110367288",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,3,Damaging,"32,97","31,38"
"low freq, many artifacts, many samples",UPN2_023,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),12803,160,12989,"0,0123181153",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,3,Damaging,"33,01","31,2"
"low freq, many artifacts, many samples",UPN2_024,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),5760,66,5841,"0,011299435",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,3,Damaging,"32,95","30,64"
"inspected, strandbias, bad alignment",UPN2_025,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),15259,198,15489,"0,0127832655",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,"0,003",Damaging,"33,08","31,11"
"low freq, many artifacts, many samples",UPN2_026,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),14280,203,14519,"0,0139816792",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,3,Damaging,"32,99","31,02"
"low freq, many artifacts, many samples",UPN2_027,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),14580,242,14860,"0,0162853297",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,3,Damaging,"33,16","31,31"
"inspected, strandbias, bad alignment",UPN2_028,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),10309,139,10466,"0,0132811007",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,"0,003",Damaging,"33,21","31,48"
"low freq, many artifacts, many samples",UPN2_044,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),3729,39,3773,"0,0103366022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,3,Damaging,"32,63","29,87"
"low freq, many artifacts, many samples",UPN2_029,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),13009,190,13222,"0,0143699894",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,3,Damaging,"32,92","31,33"
"inspected, strandbias, bad alignment",UPN2_030,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),12898,198,13133,"0,0150765248",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,"0,003",Damaging,"32,98","31,49"
"inspected, strandbias, bad alignment",UPN2_031,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),9563,115,9702,"0,0118532261",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,"0,003",Damaging,"33,01","31,77"
"low freq, many artifacts, many samples",UPN2_005,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),2528,51,2583,"0,0197444832",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,3,Damaging,"33,3",32
"low freq, many artifacts, many samples",UPN2_032,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),4379,51,4438,"0,0114916629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,3,Damaging,"33,02","30,51"
"low freq, many artifacts, many samples",UPN2_033,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),9689,112,9835,"0,0113879004",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,3,Damaging,"33,11","31,12"
"low freq, many artifacts, many samples",UPN2_034,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),3784,51,3843,"0,0132708821",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,3,Damaging,"33,03","30,73"
"inspected, strandbias, bad alignment",UPN2_035,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),12550,193,12772,"0,0151111807",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,"0,003",Damaging,"33,08","30,78"
"low freq, many artifacts, many samples",UPN2_036,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),17190,303,17520,"0,0172945205",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,3,Damaging,"32,98","31,02"
"low freq, many artifacts, many samples",UPN2_006,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),3847,74,3926,"0,018848701",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,3,Damaging,"33,49","31,12"
"inspected, strandbias, bad alignment",UPN2_037,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),21203,308,21567,"0,0142810776",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,"0,003",Damaging,"32,99","31,53"
"inspected, strandbias, bad alignment",UPN2_038,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),21671,333,22049,"0,0151027257",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,"0,003",Damaging,"33,02","31,2"
"low freq, many artifacts, many samples",UPN2_039,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),18352,305,18701,"0,0163092883",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,3,Damaging,"33,09","31,3"
"inspected, strandbias, bad alignment",UPN2_007,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),15989,228,16259,"0,0140230026",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,"0,003",Damaging,"33,36","30,85"
"inspected, strandbias, bad alignment",UPN2_008,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),24262,391,24714,"0,0158209922",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,"0,003",Damaging,"33,05","31,13"
"low freq, many artifacts, many samples",UPN2_009,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),19624,231,19908,"0,0116033755",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,3,Damaging,"33,02","31,62"
"low freq, many artifacts, many samples",UPN2_010,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),12908,173,13128,"0,0131779403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,3,Damaging,"33,51","30,72"
"low freq, many artifacts, many samples",UPN2_011,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),13173,201,13393,"0,0150078399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,3,Damaging,"33,48","30,55"
"inspected, strandbias, bad alignment",UPN2_058,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),17343,183,17597,"0,0103994999",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,"0,003",Damaging,"32,83","30,37"
"low freq, many artifacts, many samples",UPN2_012,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),8354,133,8516,"0,0156176609",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,3,Damaging,"33,41","31,38"
"low freq, many artifacts, many samples",UPN2_040,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),7636,132,7787,"0,0169513291",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,3,Damaging,"32,98","31,37"
"inspected, strandbias, bad alignment",UPN2_013,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),4677,63,4757,"0,013243641",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,"0,003",Damaging,"33,38","31,65"
"low freq, many artifacts, many samples",UPN2_062,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),9970,120,10104,"0,0118764846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,3,Damaging,"33,85","30,92"
"low freq, many artifacts, many samples",UPN2_063,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),7939,89,8054,"0,0110504097",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,3,Damaging,"34,19","30,99"
"low freq, many artifacts, many samples",UPN2_071,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),9305,169,9487,"0,0178138505",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,3,Damaging,"33,46","30,3"
"inspected, strandbias, bad alignment",UPN2_072,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),10373,120,10509,"0,0114187839",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,"0,003",Damaging,"33,82","29,66"
"low freq, many artifacts, many samples",UPN2_075,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),11007,123,11174,"0,0110076964",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,3,Damaging,"33,87","30,8"
"low freq, many artifacts",UPN2_076,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),7167,84,7264,"0,0115638767",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,3,Damaging,"33,98","30,02"
"inspected, strandbias, bad alignment",UPN2_078,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),9164,110,9287,"0,0118445138",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,"0,003",Damaging,"33,8","30,97"
"inspected, strandbias, bad alignment",UPN2_080,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),9446,117,9583,"0,0122091203",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,"0,003",Damaging,"34,06","29,85"
"inspected, strandbias, bad alignment",UPN2_081,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),13244,159,13417,"0,0118506373",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,"0,003",Damaging,"33,78","30,28"
"inspected, strandbias, bad alignment",UPN2_083,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),9149,110,9272,"0,0118636756",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,"0,003",Damaging,"33,98","30,62"
"inspected, strandbias, bad alignment",UPN2_084,2,25469031,C,G,missense_variant(MODERATE|MISSENSE|aGa/aCa|p.Arg476Thr/c.1427G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),7629,86,7738,"0,0111139829",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,"0,003",Damaging,"34,09","30,94"
"inspected, bad alignment, many artifacts",UPN2_044,2,25469076,G,A,missense_variant(MODERATE|MISSENSE|aCa/aTa|p.Thr461Ile/c.1382C>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),3767,40,3814,"0,010487677",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,"0,27",Tolerated,"34,83","34,8"
"low freq, many artifacts",UPN2_006,2,25469076,GT,G,frameshift_variant(HIGH||aca/|p.Thr461fs/c.1381delA|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),3870,40,3919,"0,0102066854",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,22",NA
"bad alignment, strandbias, many samples",UPN2_001,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),5439,637,6089,"0,1046148793",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,62","31,62"
"bad alignment, strandbias, many samples",UPN2_014,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),11512,714,12259,"0,0582429236",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,99","31,52"
"bad alignment, strandbias, many samples",UPN2_015,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),15477,757,16281,"0,0464959155",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,99","31,91"
"bad alignment, strandbias, many samples",UPN2_016,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),7501,470,7986,"0,0588529927",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,93","31,76"
"bad alignment, strandbias, many samples",UPN2_017,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),5205,267,5491,"0,0486250228",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"34,14","31,64"
"bad alignment, strandbias, many samples",UPN2_018,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),8244,495,8761,"0,0565003995",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,97","31,72"
"inspected, strandbias, bad alignment",UPN2_019,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),8478,559,9059,"0,0617065901",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,95","31,79"
"bad alignment, strandbias, many samples",UPN2_020,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),7659,404,8085,"0,0499690785",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"34,12","31,77"
"bad alignment, strandbias, many samples",UPN2_021,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),8945,600,9588,"0,0625782228",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,88","31,87"
"bad alignment, strandbias, many samples",UPN2_002,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),6847,804,7675,"0,1047557003",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,64","31,67"
"bad alignment, strandbias, many samples",UPN2_003,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),1385,187,1577,"0,1185795815",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,56","31,54"
"bad alignment, strandbias, many samples",UPN2_022,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),10437,607,11082,"0,0547735066",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,95","31,69"
"bad alignment, strandbias, many samples",UPN2_023,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),12253,742,13036,"0,0569193004",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,93","31,77"
"bad alignment, strandbias, many samples",UPN2_041,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),13822,806,14664,"0,054964539",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"32,29","31,38"
"bad alignment, strandbias, many samples",UPN2_024,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),5535,308,5856,"0,0525956284",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,98","31,69"
"bad alignment, strandbias, many samples",UPN2_025,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),14546,980,15573,"0,0629294291",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,92","31,77"
"bad alignment, strandbias, many samples",UPN2_026,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),13743,779,14558,"0,0535100975",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,97","31,88"
"bad alignment, strandbias, many samples",UPN2_004,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),876,234,1111,"0,2106210621",0,1,0,0,1,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"32,12","31,69"
"bad alignment, strandbias, many samples",UPN2_027,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),13830,1005,14876,"0,0675584835",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,9","31,47"
"bad alignment, strandbias, many samples",UPN2_089,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),9448,237,9703,"0,0244254354",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,94","31,95"
"bad alignment, strandbias, many samples",UPN2_042,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),23627,827,24556,"0,0336781235",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,54","31,73"
"bad alignment, strandbias, many samples",UPN2_028,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),9818,627,10470,"0,0598853868",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,92","31,85"
"bad alignment, strandbias, many samples",UPN2_043,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),14385,426,14864,"0,0286598493",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,7","31,39"
"inspected, strandbias, bad alignment",UPN2_044,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),3656,144,3815,"0,0377457405",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,63","31,97"
"bad alignment, strandbias, many samples",UPN2_029,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),12503,718,13267,"0,0541192432",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"34,07","31,75"
"bad alignment, strandbias, many samples",UPN2_030,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),12424,707,13179,"0,0536459519",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"34,04","31,82"
"bad alignment, strandbias, many samples",UPN2_031,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),9174,532,9736,"0,0546425637",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,91","31,77"
"bad alignment, strandbias, many samples",UPN2_005,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),2304,270,2583,"0,1045296167",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,69","31,6"
"bad alignment, strandbias, many samples",UPN2_045,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),21285,423,21797,"0,0194063403",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,75","31,69"
"bad alignment, strandbias, many samples",UPN2_032,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),4185,236,4441,"0,0531411844",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,84","31,82"
"bad alignment, strandbias, many samples",UPN2_046,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),18053,808,18928,"0,0426880811",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,58","31,81"
"bad alignment, strandbias, many samples",UPN2_033,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),9264,561,9858,"0,0569080949",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,88","31,68"
"bad alignment, strandbias, many samples",UPN2_034,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),3649,186,3854,"0,0482615464",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"34,07","31,62"
"bad alignment, strandbias, many samples",UPN2_047,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),28027,975,29144,"0,0334545704",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,63","31,57"
"bad alignment, strandbias, many samples",UPN2_048,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),16260,898,17267,"0,052006718",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,08","31,55"
"bad alignment, strandbias, many samples",UPN2_035,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),11990,763,12807,"0,0595767939",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,97","31,78"
"bad alignment, strandbias, many samples",UPN2_036,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),16574,995,17618,"0,056476331",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,99","31,59"
"bad alignment, strandbias, many samples",UPN2_006,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),3436,466,3912,"0,1191206544",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,49","31,78"
"bad alignment, strandbias, many samples",UPN2_049,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),19240,625,19980,"0,0312812813",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,59","31,79"
"bad alignment, strandbias, many samples",UPN2_050,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),19335,364,19789,"0,0183940573",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,68","31,77"
"bad alignment, strandbias, many samples",UPN2_037,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),20464,1083,21622,"0,0500878735",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"34,02","31,69"
"bad alignment, strandbias, many samples",UPN2_051,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),15733,489,16296,"0,0300073638",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,58","31,37"
"bad alignment, strandbias, many samples",UPN2_052,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),16786,396,17236,"0,0229751683",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,61","31,87"
"bad alignment, strandbias, many samples",UPN2_038,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),20833,1229,22129,"0,0555379818",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,98","31,75"
"bad alignment, strandbias, many samples",UPN2_039,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),17593,1078,18724,"0,0575731681",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,96","31,89"
"bad alignment, strandbias, many samples",UPN2_053,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),20610,776,21495,"0,0361014189",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,58","31,89"
"bad alignment, strandbias, many samples",UPN2_054,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),12335,370,12761,"0,0289945929",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,47","31,77"
"bad alignment, strandbias, many samples",UPN2_007,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),14559,1668,16268,"0,1025325793",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,55","31,61"
"bad alignment, strandbias, many samples",UPN2_008,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),22601,2106,24786,"0,0849673203",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,73","31,69"
"bad alignment, strandbias, many samples",UPN2_009,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),18462,1429,19944,"0,0716506217",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,78","31,58"
"bad alignment, strandbias, many samples",UPN2_010,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),11668,1385,13095,"0,1057655594",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,36","31,61"
"bad alignment, strandbias, many samples",UPN2_011,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),11945,1439,13416,"0,1072599881",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,42","31,72"
"bad alignment, strandbias, many samples",UPN2_055,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),21854,674,22616,"0,0298019102",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,65","31,82"
"bad alignment, strandbias, many samples",UPN2_056,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),9792,343,10173,"0,0337167011",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,56","31,83"
"bad alignment, strandbias, many samples",UPN2_090,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),8778,207,8999,"0,0230025558",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,77","32,26"
"bad alignment, strandbias, many samples",UPN2_057,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),16780,703,17568,"0,0400159381",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,51","31,78"
"bad alignment, strandbias, many samples",UPN2_058,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),16773,814,17654,"0,0461085306",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,54","31,64"
"bad alignment, strandbias, many samples",UPN2_059,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),4799,770,5587,"0,1378199391",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"32,19","31,54"
"bad alignment, strandbias, many samples",UPN2_012,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),7665,829,8522,"0,0972776344",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,44","31,73"
"bad alignment, strandbias, many samples",UPN2_060,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),7192,1085,8293,"0,1308332328",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"32,68","31,75"
"bad alignment, strandbias, many samples",UPN2_040,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),7382,385,7797,"0,0493779659",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"34,03","31,78"
"bad alignment, strandbias, many samples",UPN2_013,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),4246,501,4761,"0,1052299937",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,52","31,62"
"bad alignment, strandbias, many samples",UPN2_091,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),8289,229,8532,"0,0268401313",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"34,04","31,92"
"bad alignment, strandbias, many samples",UPN2_092,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),5041,115,5162,"0,0222781867",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,92","31,67"
"bad alignment, strandbias, many samples",UPN2_093,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),6261,164,6432,"0,0254975124",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,82","32,12"
"bad alignment, strandbias, many samples",UPN2_061,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),7675,1170,8875,"0,1318309859",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"32,57","31,64"
"bad alignment, strandbias, many samples",UPN2_062,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),8849,1223,10102,"0,1210651356",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"32,91","31,67"
"bad alignment, strandbias, many samples",UPN2_063,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),6906,1076,7998,"0,1345336334",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"32,68","31,61"
"bad alignment, strandbias, many samples",UPN2_064,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),6096,1216,7333,"0,1658257194",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"32,21","31,69"
"bad alignment, strandbias, many samples",UPN2_065,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),3975,642,4620,"0,138961039",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"32,26","31,49"
"bad alignment, strandbias, many samples",UPN2_066,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),2741,513,3264,"0,1571691176",0,1,0,0,1,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"31,92","31,64"
"bad alignment, strandbias, many samples",UPN2_067,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),2992,539,3541,"0,1522168879",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"32,09","31,56"
"bad alignment, strandbias, many samples",UPN2_068,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),4453,715,5179,"0,1380575401",0,1,0,0,1,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"32,35","31,56"
"bad alignment, strandbias, many samples",UPN2_069,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),6986,1019,8023,"0,1270098467",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"32,49","31,64"
"bad alignment, strandbias, many samples",UPN2_070,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),3988,615,4616,"0,1332322357",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"32,46","31,52"
"bad alignment, strandbias, many samples",UPN2_071,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),8517,944,9487,"0,0995045852",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,3","31,46"
"bad alignment, strandbias, many samples",UPN2_072,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),9210,1210,10467,"0,115601414",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,01","31,52"
"bad alignment, strandbias, many samples",UPN2_073,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),5748,842,6600,"0,1275757576",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"32,65","31,59"
"bad alignment, strandbias, many samples",UPN2_074,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),2941,469,3416,"0,137295082",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"32,31","31,7"
"bad alignment, strandbias, many samples",UPN2_075,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),9927,1172,11128,"0,1053199137",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"32,96","31,58"
"bad alignment, strandbias, many samples",UPN2_076,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),6453,772,7243,"0,1065856689",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"32,83","31,52"
"bad alignment, strandbias, many samples",UPN2_077,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),5333,878,6220,"0,1411575563",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"32,4","31,57"
"bad alignment, strandbias, many samples",UPN2_078,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),8248,1014,9282,"0,1092436975",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,08","31,63"
"bad alignment, strandbias, many samples",UPN2_079,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),4680,590,5293,"0,1114679766",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"32,71","31,55"
"bad alignment, strandbias, many samples",UPN2_080,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),8341,1164,9525,"0,1222047244",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"32,84","31,57"
"bad alignment, strandbias, many samples",UPN2_081,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),12134,1256,13422,"0,0935777082",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"32,94","31,67"
"bad alignment, strandbias, many samples",UPN2_082,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),4526,622,5160,"0,1205426357",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"32,39","31,68"
"bad alignment, strandbias, many samples",UPN2_083,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),8083,1151,9261,"0,1242846345",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"32,77","31,43"
"bad alignment, strandbias, many samples",UPN2_084,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),6879,805,7704,"0,1044911734",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"32,74","31,52"
"bad alignment, strandbias, many samples",UPN2_085,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),3632,466,4107,"0,1134648162",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"32,61","31,74"
"bad alignment, strandbias, many samples",UPN2_086,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),1970,240,2210,"0,1085972851",0,1,0,0,1,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"32,49","31,55"
"bad alignment, strandbias, many samples",UPN2_087,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),6175,877,7068,"0,1240803622",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"32,45","31,68"
"bad alignment, strandbias, many samples",UPN2_088,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),4421,713,5153,"0,1383660004",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"32,47","31,67"
"bad alignment, strandbias, many samples",UPN2_094,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),11969,306,12292,"0,0248942402",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,86","31,77"
"bad alignment, strandbias, many samples",UPN2_095,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),10001,267,10283,"0,0259651853",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,79","31,89"
"bad alignment, strandbias, many samples",UPN2_096,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),11005,228,11248,"0,0202702703",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,93","32,05"
"bad alignment, strandbias, many samples",UPN2_097,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),13436,364,13818,"0,0263424519",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,99","31,63"
"bad alignment, strandbias, many samples",UPN2_098,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),9501,225,9739,"0,023102988",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,94","31,5"
"bad alignment, strandbias, many samples",UPN2_099,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),5125,134,5266,"0,025446259",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,96","32,25"
"bad alignment, strandbias, many samples",UPN2_100,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),8462,227,8699,"0,0260949534",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,82","31,81"
"bad alignment, strandbias, many samples",UPN2_101,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),8744,198,8950,"0,022122905",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,71","31,77"
"bad alignment, strandbias, many samples",UPN2_102,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),8875,237,9130,"0,025958379",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,81","31,8"
"bad alignment, strandbias, many samples",UPN2_103,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),8873,240,9133,"0,0262783313",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,79","31,69"
"bad alignment, strandbias, many samples",UPN2_104,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),11359,291,11663,"0,0249506988",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,93","31,67"
"bad alignment, strandbias, many samples",UPN2_105,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),10227,254,10499,"0,0241927803",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,83","31,78"
"bad alignment, strandbias, many samples",UPN2_106,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),15303,310,15633,"0,0198298471",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,81","31,83"
"bad alignment, strandbias, many samples",UPN2_107,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),16338,349,16713,"0,0208819482",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,93","31,72"
"bad alignment, strandbias, many samples",UPN2_108,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),12917,267,13200,"0,0202272727",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,83","31,47"
"bad alignment, strandbias, many samples",UPN2_109,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),12868,235,13129,"0,0178993069",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,88","31,7"
"bad alignment, strandbias, many samples",UPN2_110,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),14096,211,14329,"0,0147253821",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,84","31,86"
"bad alignment, strandbias, many samples",UPN2_111,2,25469083,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys459Glu/c.1375A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),11214,258,11489,"0,0224562625",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,028",Damaging,"33,94","31,62"
"inspected, many artifacts",UPN2_006,2,25469086,G,A,missense_variant(MODERATE|MISSENSE|Cgg/Tgg|p.Arg458Trp/c.1372C>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),1829,22,1860,"0,011827957",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,"0,003",Damaging,35,"33,82"
"inspected, many artifacts",UPN2_041,2,25469088,G,A,missense_variant(MODERATE|MISSENSE|cCc/cTc|p.Pro457Leu/c.1370C>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),2551,33,2593,"0,0127265715",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,11",Neutral,"0,151",Tolerated,"34,06","32,42"
"low bq, low freq, many artifacts",UPN2_044,2,25469092,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys456*/c.1366A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),2414,29,2452,"0,0118270799",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,64","19,17"
"inspected, many artifacts",UPN2_041,2,25469102,TG,T,frameshift_variant(HIGH||cca/|p.Pro452fs/c.1355delC|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|T),2550,26,2588,"0,0100463679",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,03",NA
"inspected, many artifacts",UPN2_006,2,25469121,G,A,missense_variant(MODERATE|MISSENSE|gCt/gTt|p.Ala446Val/c.1337C>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),1820,36,1859,"0,0193652501",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,"0,099",Tolerated,"34,77","31,33"
"low bq, low freq, many artifacts, many samples",UPN2_041,2,25469132,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu442Asp/c.1326A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),2542,31,2585,"0,0119922631",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,21",Neutral,239,Tolerated,"33,43","17,84"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,25469132,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu442Asp/c.1326A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),10039,104,10190,"0,0102060844",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,21",Neutral,239,Tolerated,"33,82","17,13"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,25469132,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu442Asp/c.1326A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),10431,112,10587,"0,010579012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,21",Neutral,239,Tolerated,"33,79","17,64"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25469136,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val441Gly/c.1322T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),2319,35,2365,"0,0147991543",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,22",Neutral,104,Tolerated,"27,88","14,2"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25469136,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val441Gly/c.1322T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),2391,33,2439,"0,0135301353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,22",Neutral,104,Tolerated,"27,78","16,24"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25469136,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val441Gly/c.1322T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),3520,63,3604,"0,0174805771",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,22",Neutral,104,Tolerated,"27,86","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25469136,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val441Gly/c.1322T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),2112,39,2158,"0,0180722892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,22",Neutral,104,Tolerated,"28,41","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25469136,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val441Gly/c.1322T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),1734,24,1771,"0,0135516657",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,22",Neutral,104,Tolerated,"28,29",14
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25469136,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val441Gly/c.1322T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),4301,64,4387,"0,0145885571",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,22",Neutral,104,Tolerated,"28,34","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25469136,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val441Gly/c.1322T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),3813,60,3887,"0,0154360689",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,22",Neutral,104,Tolerated,"28,09","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25469136,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val441Gly/c.1322T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),1625,23,1657,"0,0138805069",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,22",Neutral,104,Tolerated,"27,96","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25469136,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val441Gly/c.1322T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),3851,64,3929,"0,0162891321",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,22",Neutral,104,Tolerated,"28,2","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25469136,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val441Gly/c.1322T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),2354,39,2411,"0,0161758606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,22",Neutral,104,Tolerated,"28,02","14,92"
"low bq, many samples",UPN2_077,2,25469136,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val441Gly/c.1322T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),1097,28,1130,"0,0247787611",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,22",Neutral,104,Tolerated,"28,2","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25469136,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val441Gly/c.1322T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),3444,58,3525,"0,0164539007",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,22",Neutral,104,Tolerated,"28,02","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25469136,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val441Gly/c.1322T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),1552,25,1590,"0,0157232704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,22",Neutral,104,Tolerated,"28,36","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25469136,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val441Gly/c.1322T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),2909,40,2964,"0,0134952767",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,22",Neutral,104,Tolerated,28,"14,68"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25469136,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val441Gly/c.1322T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),4839,69,4931,"0,0139931048",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,22",Neutral,104,Tolerated,"27,97","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25469136,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val441Gly/c.1322T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),2723,54,2804,"0,0192582026",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,22",Neutral,104,Tolerated,"27,83","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25469136,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val441Gly/c.1322T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),2243,36,2289,"0,0157273919",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,22",Neutral,104,Tolerated,"28,26","16,28"
"low bq, low freq, many artifacts, many samples",UPN2_087,2,25469136,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val441Gly/c.1322T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),1540,24,1575,"0,0152380952",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,22",Neutral,104,Tolerated,"28,56","14,58"
"low bq, low freq, many artifacts",UPN2_088,2,25469136,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val441Gly/c.1322T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|C),1105,25,1139,"0,0219490781",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,22",Neutral,104,Tolerated,"27,94","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_041,2,25469143,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met439Leu/c.1315A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),2533,31,2582,"0,0120061967",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,306,Tolerated,"33,08","17,42"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,25469143,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met439Leu/c.1315A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),15033,163,15265,"0,0106780216",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,306,Tolerated,"33,19","17,11"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,25469143,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met439Leu/c.1315A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),9598,104,9768,"0,0106470106",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,306,Tolerated,"33,23","19,37"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,25469143,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met439Leu/c.1315A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),14938,166,15185,"0,0109318406",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,306,Tolerated,"33,31","17,44"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,25469143,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met439Leu/c.1315A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),18413,209,18705,"0,011173483",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,306,Tolerated,"33,13","19,24"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,25469143,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met439Leu/c.1315A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),12537,149,12745,"0,0116908592",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,306,Tolerated,"33,06",18
"low bq, low freq, many artifacts, many samples",UPN2_050,2,25469143,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met439Leu/c.1315A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),13256,136,13476,"0,0100920154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,306,Tolerated,"33,23","16,93"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,25469143,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met439Leu/c.1315A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),11016,134,11206,"0,0119578797",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,306,Tolerated,"33,07","17,54"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,25469143,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met439Leu/c.1315A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),7617,91,7742,"0,0117540687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,306,Tolerated,"33,12","17,2"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,25469143,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met439Leu/c.1315A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),10376,142,10570,"0,0134342479",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,306,Tolerated,"33,15","18,8"
"low bq, low freq, many artifacts",UPN2_061,2,25469143,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met439Leu/c.1315A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),2398,25,2436,"0,0102627258",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,306,Tolerated,"33,44","15,76"
"low bq, low freq, many artifacts",UPN2_048,2,25469145,T,A,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp438Val/c.1313A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),7832,80,7946,"0,0100679587",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,16",Neutral,8,Damaging,"33,7","23,35"
"low bq, low freq, many artifacts, many samples",UPN2_041,2,25469149,T,A,missense_variant(MODERATE|MISSENSE|Acg/Tcg|p.Thr437Ser/c.1309A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),2532,38,2585,"0,0147001934",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,2",Neutral,502,Tolerated,"32,53","16,08"
"low bq, low freq, many artifacts, many samples",UPN2_024,2,25469149,T,A,missense_variant(MODERATE|MISSENSE|Acg/Tcg|p.Thr437Ser/c.1309A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),3727,41,3785,"0,0108322325",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,2",Neutral,502,Tolerated,"33,35","18,17"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,25469149,T,A,missense_variant(MODERATE|MISSENSE|Acg/Tcg|p.Thr437Ser/c.1309A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),15019,193,15285,"0,0126267583",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,2",Neutral,502,Tolerated,"32,75","18,38"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,25469149,T,A,missense_variant(MODERATE|MISSENSE|Acg/Tcg|p.Thr437Ser/c.1309A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),9637,106,9790,"0,0108273749",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,2",Neutral,502,Tolerated,"32,61","16,53"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,25469149,T,A,missense_variant(MODERATE|MISSENSE|Acg/Tcg|p.Thr437Ser/c.1309A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),2389,37,2443,"0,0151453131",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,2",Neutral,502,Tolerated,"32,41","18,3"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,25469149,T,A,missense_variant(MODERATE|MISSENSE|Acg/Tcg|p.Thr437Ser/c.1309A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),14947,173,15209,"0,0113748438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,2",Neutral,502,Tolerated,"32,56","16,9"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,25469149,T,A,missense_variant(MODERATE|MISSENSE|Acg/Tcg|p.Thr437Ser/c.1309A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),11807,141,12026,"0,0117245967",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,2",Neutral,502,Tolerated,"32,51","16,66"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,25469149,T,A,missense_variant(MODERATE|MISSENSE|Acg/Tcg|p.Thr437Ser/c.1309A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),18364,254,18707,"0,0135778051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,2",Neutral,502,Tolerated,"32,49","18,19"
"low bq, low freq, many artifacts, many samples",UPN2_048,2,25469149,T,A,missense_variant(MODERATE|MISSENSE|Acg/Tcg|p.Thr437Ser/c.1309A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),7820,108,7959,"0,0135695439",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,2",Neutral,502,Tolerated,"32,46","16,82"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,25469149,T,A,missense_variant(MODERATE|MISSENSE|Acg/Tcg|p.Thr437Ser/c.1309A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),12522,166,12784,"0,0129849812",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,2",Neutral,502,Tolerated,"32,49","18,07"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,25469149,T,A,missense_variant(MODERATE|MISSENSE|Acg/Tcg|p.Thr437Ser/c.1309A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),13250,168,13496,"0,0124481328",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,2",Neutral,502,Tolerated,"32,62","17,04"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,25469149,T,A,missense_variant(MODERATE|MISSENSE|Acg/Tcg|p.Thr437Ser/c.1309A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),10218,132,10422,"0,0126655153",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,2",Neutral,502,Tolerated,"32,28","17,24"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,25469149,T,A,missense_variant(MODERATE|MISSENSE|Acg/Tcg|p.Thr437Ser/c.1309A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),11001,141,11205,"0,012583668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,2",Neutral,502,Tolerated,"32,48","17,35"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,25469149,T,A,missense_variant(MODERATE|MISSENSE|Acg/Tcg|p.Thr437Ser/c.1309A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),13434,166,13686,"0,0121291831",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,2",Neutral,502,Tolerated,"32,43","17,93"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,25469149,T,A,missense_variant(MODERATE|MISSENSE|Acg/Tcg|p.Thr437Ser/c.1309A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),7656,101,7794,"0,0129586862",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,2",Neutral,502,Tolerated,"32,4","16,68"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,25469149,T,A,missense_variant(MODERATE|MISSENSE|Acg/Tcg|p.Thr437Ser/c.1309A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),14748,181,15028,"0,0120441842",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,2",Neutral,502,Tolerated,"32,46","17,56"
"low bq, low freq, many artifacts, many samples",UPN2_056,2,25469149,T,A,missense_variant(MODERATE|MISSENSE|Acg/Tcg|p.Thr437Ser/c.1309A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),6116,75,6215,"0,0120675784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,2",Neutral,502,Tolerated,"32,58","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,25469149,T,A,missense_variant(MODERATE|MISSENSE|Acg/Tcg|p.Thr437Ser/c.1309A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),10704,131,10900,"0,0120183486",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,2",Neutral,502,Tolerated,"32,62","16,47"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,25469149,T,A,missense_variant(MODERATE|MISSENSE|Acg/Tcg|p.Thr437Ser/c.1309A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),10387,148,10595,"0,0139688532",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,2",Neutral,502,Tolerated,"32,41","16,78"
"low bq, low freq, many artifacts",UPN2_073,2,25469149,T,A,missense_variant(MODERATE|MISSENSE|Acg/Tcg|p.Thr437Ser/c.1309A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),1629,20,1655,"0,0120845921",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,2",Neutral,502,Tolerated,"33,26",14
"low bq, many samples",UPN2_059,2,25469151,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr436Ser/c.1307A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),1396,51,1451,"0,0351481737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,152,Tolerated,"28,86","15,65"
"low bq, many samples",UPN2_060,2,25469151,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr436Ser/c.1307A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),4560,150,4739,"0,0316522473",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,152,Tolerated,"29,01","16,04"
"low bq, many samples",UPN2_061,2,25469151,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr436Ser/c.1307A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),4696,131,4853,"0,0269936122",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,152,Tolerated,"29,09","15,66"
"low bq, many samples",UPN2_062,2,25469151,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr436Ser/c.1307A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),6966,200,7211,"0,0277354042",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,152,Tolerated,"28,71","16,53"
"low bq, many samples",UPN2_063,2,25469151,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr436Ser/c.1307A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),4164,140,4324,"0,0323774283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,152,Tolerated,"28,74","16,36"
"low bq, many samples",UPN2_064,2,25469151,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr436Ser/c.1307A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),2031,56,2096,"0,0267175573",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,152,Tolerated,"28,93","15,71"
"low bq, many samples",UPN2_065,2,25469151,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr436Ser/c.1307A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),1477,36,1518,"0,023715415",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,152,Tolerated,"29,2","14,92"
"low bq, many samples",UPN2_067,2,25469151,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr436Ser/c.1307A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),787,25,821,"0,0304506699",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,152,Tolerated,"28,81","15,32"
"low bq, many samples",UPN2_068,2,25469151,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr436Ser/c.1307A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),1759,44,1811,"0,0242959691",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,152,Tolerated,"28,8","16,95"
"low bq, many samples",UPN2_069,2,25469151,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr436Ser/c.1307A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),3405,126,3541,"0,0355831686",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,152,Tolerated,"29,02","16,02"
"low bq, many samples",UPN2_070,2,25469151,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr436Ser/c.1307A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),1856,73,1948,"0,0374743326",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,152,Tolerated,"28,93","16,62"
"low bq, many samples",UPN2_071,2,25469151,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr436Ser/c.1307A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),8443,258,8749,"0,0294890845",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,152,Tolerated,"28,81","15,98"
"low bq, many samples",UPN2_072,2,25469151,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr436Ser/c.1307A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),7517,229,7791,"0,0293928892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,152,Tolerated,"28,83","15,58"
"low bq, many samples",UPN2_073,2,25469151,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr436Ser/c.1307A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),3203,102,3317,"0,0307506783",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,152,Tolerated,"29,06","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,25469151,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr436Ser/c.1307A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),1346,30,1387,"0,021629416",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,152,Tolerated,"28,8","16,97"
"low bq, many samples",UPN2_075,2,25469151,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr436Ser/c.1307A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),7591,207,7827,"0,0264469145",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,152,Tolerated,"29,13","15,54"
"low bq, many samples",UPN2_076,2,25469151,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr436Ser/c.1307A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),4617,172,4822,"0,0356698465",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,152,Tolerated,"28,82","16,77"
"low bq, many samples",UPN2_077,2,25469151,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr436Ser/c.1307A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),2163,77,2249,"0,0342374389",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,152,Tolerated,"28,87","15,73"
"low bq, many samples",UPN2_078,2,25469151,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr436Ser/c.1307A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),6791,237,7057,"0,0335836758",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,152,Tolerated,"29,07","15,85"
"low bq, many samples",UPN2_079,2,25469151,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr436Ser/c.1307A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),3047,109,3171,"0,0343740145",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,152,Tolerated,"28,89","16,02"
"low bq, many samples",UPN2_080,2,25469151,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr436Ser/c.1307A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),5691,190,5913,"0,0321325892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,152,Tolerated,"29,11",16
"low bq, many samples",UPN2_081,2,25469151,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr436Ser/c.1307A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),9573,279,9904,"0,0281704362",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,152,Tolerated,"29,06","16,36"
"low bq, many samples",UPN2_082,2,25469151,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr436Ser/c.1307A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),2149,55,2216,"0,0248194946",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,152,Tolerated,"28,96","16,89"
"low bq, many samples",UPN2_083,2,25469151,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr436Ser/c.1307A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),5423,171,5606,"0,0305030325",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,152,Tolerated,"29,01","15,24"
"low bq, many samples",UPN2_084,2,25469151,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr436Ser/c.1307A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),4394,170,4585,"0,0370774264",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,152,Tolerated,"28,84","15,87"
"low bq, many samples",UPN2_085,2,25469151,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr436Ser/c.1307A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),2036,61,2110,"0,0289099526",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,152,Tolerated,"28,89","16,08"
"low bq, many samples",UPN2_086,2,25469151,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr436Ser/c.1307A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),1073,28,1111,"0,0252025203",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,152,Tolerated,"29,14","15,89"
"low bq, many samples",UPN2_087,2,25469151,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr436Ser/c.1307A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),3022,110,3150,"0,0349206349",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,152,Tolerated,"29,04","16,36"
low bq,UPN2_088,2,25469151,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr436Ser/c.1307A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),2194,72,2276,"0,0316344464",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,152,Tolerated,"29,09","16,85"
"low bq, low freq, many artifacts",UPN2_085,2,25469154,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val435Glu/c.1304T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|T),2078,27,2119,"0,0127418594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,3",Neutral,188,Tolerated,"30,93","24,11"
"inspected, many artifacts",UPN2_006,2,25469166,G,A,missense_variant(MODERATE|MISSENSE|cCc/cTc|p.Pro431Leu/c.1292C>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),3634,78,3723,"0,0209508461",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,72",Deleterious,"0,069",Tolerated,"33,07","34,44"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,25469169,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn430Thr/c.1289A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),1431,21,1457,"0,0144131778",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,44,Damaging,"27,7","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25469169,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn430Thr/c.1289A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),4660,71,4754,"0,0149347918",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,44,Damaging,"27,67","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25469169,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn430Thr/c.1289A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),4748,88,4889,"0,0179995909",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,44,Damaging,"27,91","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25469169,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn430Thr/c.1289A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),7087,113,7256,"0,0155733186",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,44,Damaging,"27,58","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25469169,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn430Thr/c.1289A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),4244,74,4344,"0,0170349908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,44,Damaging,"27,69","15,69"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25469169,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn430Thr/c.1289A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),2054,34,2107,"0,0161366872",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,44,Damaging,"27,73","16,94"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,25469169,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn430Thr/c.1289A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),1490,24,1521,"0,0157790927",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,44,Damaging,"28,22","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25469169,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn430Thr/c.1289A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),1768,37,1817,"0,0203632361",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,44,Damaging,"27,87","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25469169,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn430Thr/c.1289A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),3498,50,3568,"0,0140134529",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,44,Damaging,28,"15,76"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,25469169,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn430Thr/c.1289A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),1924,34,1965,"0,017302799",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,44,Damaging,"27,71","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25469169,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn430Thr/c.1289A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),8627,126,8807,"0,0143068014",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,44,Damaging,"27,72","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25469169,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn430Thr/c.1289A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),7644,123,7827,"0,0157148333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,44,Damaging,"27,71","15,75"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25469169,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn430Thr/c.1289A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),3276,50,3341,"0,0149655792",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,44,Damaging,"27,7","15,48"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,25469169,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn430Thr/c.1289A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),1379,20,1405,"0,0142348754",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,44,Damaging,"28,04",14
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25469169,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn430Thr/c.1289A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),7720,129,7887,"0,0163560289",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,44,Damaging,"27,92","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25469169,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn430Thr/c.1289A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),4729,85,4847,"0,0175366206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,44,Damaging,"27,7","15,51"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25469169,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn430Thr/c.1289A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),2211,37,2262,"0,016357206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,44,Damaging,"27,68","15,54"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25469169,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn430Thr/c.1289A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),6915,119,7087,"0,016791308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,44,Damaging,"27,66","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25469169,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn430Thr/c.1289A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),3122,49,3191,"0,0153556879",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,44,Damaging,"27,64","17,1"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25469169,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn430Thr/c.1289A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),5835,81,5949,"0,0136157337",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,44,Damaging,"27,71","16,15"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25469169,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn430Thr/c.1289A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),9754,134,9946,"0,0134727529",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,44,Damaging,28,"15,14"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25469169,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn430Thr/c.1289A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),2177,26,2224,"0,0116906475",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,44,Damaging,"28,01",15
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25469169,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn430Thr/c.1289A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),5500,91,5638,"0,0161404753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,44,Damaging,"27,74","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25469169,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn430Thr/c.1289A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),4498,68,4606,"0,0147633521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,44,Damaging,"27,76","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,25469169,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn430Thr/c.1289A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),2072,37,2119,"0,0174610665",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,44,Damaging,"27,97","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_087,2,25469169,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn430Thr/c.1289A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),3102,39,3168,"0,0123106061",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,44,Damaging,"27,59","14,67"
"low bq, low freq, many artifacts",UPN2_088,2,25469169,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn430Thr/c.1289A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),2246,27,2288,"0,0118006993",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,44,Damaging,"27,68",15
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25469170,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn430His/c.1288A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),4662,59,4754,"0,0124106016",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,"0,03",Damaging,"29,65","17,66"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25469170,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn430His/c.1288A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),4814,54,4889,"0,0110452035",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,"0,03",Damaging,"29,86","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25469170,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn430His/c.1288A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),7119,98,7256,"0,0135060639",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,"0,03",Damaging,"29,86","15,31"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25469170,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn430His/c.1288A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),4275,51,4344,"0,0117403315",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,"0,03",Damaging,"29,71","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25469170,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn430His/c.1288A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),2058,39,2107,"0,0185097295",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,"0,03",Damaging,"29,58","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25469170,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn430His/c.1288A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),1787,20,1817,"0,0110071547",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,"0,03",Damaging,"29,77",14
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25469170,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn430His/c.1288A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),3486,48,3566,"0,0134604599",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,"0,03",Damaging,"29,87","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,25469170,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn430His/c.1288A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),1931,26,1965,"0,0132315522",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,"0,03",Damaging,"29,47","16,19"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25469170,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn430His/c.1288A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),8674,110,8806,"0,0124914831",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,"0,03",Damaging,"29,78","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25469170,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn430His/c.1288A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),7698,98,7827,"0,0125207615",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,"0,03",Damaging,"29,87","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25469170,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn430His/c.1288A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),7757,97,7887,"0,0122987194",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,"0,03",Damaging,"29,79","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25469170,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn430His/c.1288A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),4761,52,4846,"0,0107304994",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,"0,03",Damaging,"29,57","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25469170,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn430His/c.1288A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),6968,80,7087,"0,0112882743",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,"0,03",Damaging,"29,83","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25469170,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn430His/c.1288A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),3132,42,3191,"0,0131620182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,"0,03",Damaging,"29,49","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25469170,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn430His/c.1288A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),5855,69,5947,"0,0116024886",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,"0,03",Damaging,"29,79","15,3"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25469170,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn430His/c.1288A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),9771,129,9943,"0,0129739515",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,"0,03",Damaging,"29,94","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25469170,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn430His/c.1288A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),2185,28,2224,"0,0125899281",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,"0,03",Damaging,"29,93","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25469170,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn430His/c.1288A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),5537,60,5638,"0,0106420717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,"0,03",Damaging,"29,63","15,57"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25469170,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn430His/c.1288A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),4527,65,4606,"0,0141120278",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,"0,03",Damaging,"29,5","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,25469170,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn430His/c.1288A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),2062,39,2119,"0,018404908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,"0,03",Damaging,"29,88","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_087,2,25469170,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn430His/c.1288A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),3112,42,3168,"0,0132575758",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,"0,03",Damaging,"29,89","14,43"
"low bq, low freq, many artifacts",UPN2_088,2,25469170,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn430His/c.1288A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),2247,23,2288,"0,0100524476",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,"0,03",Damaging,"29,8","14,3"
"inspected, many artifacts",UPN2_044,2,25469171,C,G,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys429Asn/c.1287G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|G),4849,54,4913,"0,0109912477",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,"0,017",Damaging,"33,33","31,63"
"inspected, many artifacts",UPN2_044,2,25469174,C,A,missense_variant(MODERATE|MISSENSE|gaG/gaT|p.Glu428Asp/c.1284G>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|A),4848,53,4911,"0,0107920994",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,67",Neutral,"0,176",Tolerated,"32,51","30,11"
"inspected, many artifacts",UPN2_044,2,25469176,C,T,missense_variant(MODERATE|MISSENSE|Gag/Aag|p.Glu428Lys/c.1282G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|11|T),4838,58,4909,"0,0118150336",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,"0,062",Tolerated,"33,16","32,12"
"inspected, many artifacts",UPN2_044,2,25469488,C,T,splice_donor_variant+intron_variant(HIGH|||c.1279+1G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|T),1866,34,1904,"0,0178571429",0,0,0,0,1,0,0,1,2,"0,0117",NO,NO,NO,O,NO,rs374440649,NO,NO,NO,NO,,,,,"35,32","35,74"
"inspected, many artifacts",UPN2_062,2,25469516,C,T,missense_variant(MODERATE|MISSENSE|Ggc/Agc|p.Gly418Ser/c.1252G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|T),1931,29,1960,"0,0147959184",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,"0,004",Damaging,"35,35","35,24"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25469519,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser417Ala/c.1249T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),1915,25,1960,"0,012755102",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,02",Neutral,63,Tolerated,"29,17","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25469519,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser417Ala/c.1249T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),2681,33,2720,"0,0121323529",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,02",Neutral,63,Tolerated,"29,08","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25469519,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser417Ala/c.1249T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),2436,34,2482,"0,0136986301",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,02",Neutral,63,Tolerated,"29,01","15,62"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25469519,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser417Ala/c.1249T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),2034,23,2059,"0,0111704711",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,02",Neutral,63,Tolerated,"29,16","15,57"
"low bq, low freq, many artifacts",UPN2_081,2,25469519,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser417Ala/c.1249T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),3047,49,3108,"0,0157657658",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,02",Neutral,63,Tolerated,"29,32","15,73"
"inspected, many artifacts",UPN2_006,2,25469519,A,G,missense_variant(MODERATE|MISSENSE|Tct/Cct|p.Ser417Pro/c.1249T>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),1669,23,1701,"0,013521458",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,"0,02",Damaging,"29,44","34,3"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25469527,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe414Cys/c.1241T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),1358,21,1384,"0,0151734104",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,02",Deleterious,0,Damaging,"30,23","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25469527,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe414Cys/c.1241T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),2444,26,2482,"0,010475423",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,02",Deleterious,0,Damaging,"29,66","14,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,2,25469528,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe414Val/c.1240T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),1608,21,1637,"0,0128283445",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,01",Deleterious,34,Damaging,"26,96","14,86"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,2,25469528,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe414Val/c.1240T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),1926,25,1960,"0,012755102",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,01",Deleterious,34,Damaging,"26,75","15,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,2,25469528,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe414Val/c.1240T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),2444,28,2482,"0,0112812248",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,01",Deleterious,34,Damaging,"26,77","16,32"
"low bq, low freq, many artifacts",UPN2_080,2,25469528,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe414Val/c.1240T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),2031,21,2058,"0,0102040816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,01",Deleterious,34,Damaging,"27,05",14
"inspected, many samples, homopolymer 6C, ins and del",UPN2_036,2,25469529,G,GC,frameshift_variant(HIGH||ggc/ggGc|p.Phe414fs/c.1238dupG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|GC),7265,144,7272,"0,0198019802",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,44",NA
"inspected, many samples, homopolymer 6C, ins and del",UPN2_039,2,25469529,G,GC,frameshift_variant(HIGH||ggc/ggGc|p.Phe414fs/c.1238dupG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|GC),6847,131,6855,"0,0191101386",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,41",NA
"inspected, many samples, homopolymer 6C, ins and del",UPN2_040,2,25469529,G,GC,frameshift_variant(HIGH||ggc/ggGc|p.Phe414fs/c.1238dupG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|GC),3055,63,3063,"0,0205680705",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,56",NA
"many samples, homopolymer 6C, low freq",UPN2_001,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),2192,25,2221,"0,0112561909",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,46",NA
"many samples, homopolymer 6C, low freq",UPN2_014,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),4401,55,4469,"0,0123070038",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,45",NA
"many samples, homopolymer 6C, low freq",UPN2_015,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),6250,83,6354,"0,0130626377",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,48",NA
"many samples, homopolymer 6C, low freq",UPN2_016,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),2744,36,2787,"0,0129171152",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,53",NA
"many samples, homopolymer 6C, low freq",UPN2_018,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),2996,36,3036,"0,0118577075",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,47",NA
"many samples, homopolymer 6C, low freq",UPN2_020,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),2988,48,3041,"0,0157842815",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,53",NA
"many samples, homopolymer 6C, low freq",UPN2_021,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),3439,42,3497,"0,0120102945",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,49",NA
"many samples, homopolymer 6C, low freq",UPN2_002,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),2963,34,3000,"0,0113333333",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,39",NA
"many samples, homopolymer 6C, low freq",UPN2_022,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),4160,44,4209,"0,0104537895",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,43",NA
"many samples, homopolymer 6C, low freq",UPN2_023,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),5024,72,5109,"0,0140927775",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,49",NA
"many samples, homopolymer 6C, low freq",UPN2_041,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),13388,152,13591,"0,0111838717",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,08",NA
"many samples, homopolymer 6C, low freq",UPN2_024,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),2123,33,2163,"0,0152565881",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,46",NA
"many samples, homopolymer 6C, low freq",UPN2_025,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),5165,61,5233,"0,0116567934",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,4",NA
"many samples, homopolymer 6C, low freq",UPN2_026,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),5202,66,5277,"0,0125071063",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,46",NA
"many samples, homopolymer 6C, low freq",UPN2_027,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),5902,75,5996,"0,0125083389",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,44",NA
"many samples, homopolymer 6C, low freq",UPN2_089,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),3631,50,3686,"0,0135648399",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,39",NA
"many samples, homopolymer 6C, low freq",UPN2_042,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),7432,107,7576,"0,014123548",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,1",NA
"many samples, homopolymer 6C, low freq",UPN2_043,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),4902,77,5003,"0,0153907655",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,15",NA
"many samples, homopolymer 6C, low freq",UPN2_044,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),1869,25,1903,"0,0131371519",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,05",NA
"many samples, homopolymer 6C, low freq",UPN2_029,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),5444,60,5515,"0,0108794198",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,39",NA
"many samples, homopolymer 6C, low freq",UPN2_030,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),4595,57,4660,"0,0122317597",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,49",NA
"many samples, homopolymer 6C, low freq",UPN2_031,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),2966,37,3007,"0,0123046225",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,49",NA
"many samples, homopolymer 6C, low freq",UPN2_045,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),6717,98,6834,"0,0143400644",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,11",NA
"many samples, homopolymer 6C, low freq",UPN2_032,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),1813,33,1854,"0,0177993528",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,51",NA
"many samples, homopolymer 6C, low freq",UPN2_046,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),6701,84,6806,"0,0123420511",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,17",NA
"many samples, homopolymer 6C, low freq",UPN2_033,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),3612,40,3657,"0,0109379273",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,45",NA
"many samples, homopolymer 6C, low freq",UPN2_047,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),9561,118,9706,"0,0121574284",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,22",NA
"many samples, homopolymer 6C, low freq",UPN2_048,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),10413,135,10613,"0,0127202488",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,14",NA
"many samples, homopolymer 6C, low freq",UPN2_035,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),4675,53,4738,"0,0111861545",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,49",NA
"many samples, homopolymer 6C, low freq",UPN2_036,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),7169,90,7272,"0,0123762376",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,42",NA
"many samples, homopolymer 6C, low freq",UPN2_049,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),7092,103,7213,"0,0142797726",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,1",NA
"many samples, homopolymer 6C, low freq",UPN2_050,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),6090,74,6187,"0,0119605625",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,14",NA
"many samples, homopolymer 6C, low freq",UPN2_037,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),8002,97,8121,"0,0119443418",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,4",NA
"many samples, homopolymer 6C, low freq",UPN2_051,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),5026,73,5118,"0,0142633841",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,19",NA
"many samples, homopolymer 6C, low freq",UPN2_052,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),6157,103,6278,"0,0164064989",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,22",NA
"many samples, homopolymer 6C, low freq",UPN2_038,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),8057,106,8177,"0,0129631894",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,41",NA
"many samples, homopolymer 6C, low freq",UPN2_039,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),6740,89,6855,"0,0129832239",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,4",NA
"many samples, homopolymer 6C, low freq",UPN2_053,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),6768,110,6912,"0,0159143519",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,18",NA
"many samples, homopolymer 6C, low freq",UPN2_054,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),4918,81,5018,"0,0161418892",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,15",NA
"many samples, homopolymer 6C, low freq",UPN2_011,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),4626,58,4692,"0,0123614663",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,41",NA
"many samples, homopolymer 6C, low freq",UPN2_055,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),7213,97,7332,"0,0132296781",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,11",NA
"many samples, homopolymer 6C, low freq",UPN2_056,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),4248,52,4322,"0,0120314669",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,04",NA
"many samples, homopolymer 6C, low freq",UPN2_090,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),3383,41,3433,"0,0119429071",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,32",NA
"many samples, homopolymer 6C, low freq",UPN2_057,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),6094,70,6180,"0,0113268608",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,06",NA
"many samples, homopolymer 6C, low freq",UPN2_058,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),7002,113,7140,"0,0158263305",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,05",NA
"many samples, homopolymer 6C, low freq",UPN2_012,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),2994,32,3035,"0,0105436573",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,5",NA
"many samples, homopolymer 6C, low freq",UPN2_040,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),3019,37,3063,"0,0120796605",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,44",NA
"many samples, homopolymer 6C, low freq",UPN2_013,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),1599,26,1628,"0,015970516",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,48",NA
"many samples, homopolymer 6C, low freq",UPN2_091,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),3323,49,3377,"0,01450992",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,41",NA
"many samples, homopolymer 6C, low freq",UPN2_092,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),2395,33,2436,"0,013546798",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,32",NA
"many samples, homopolymer 6C, low freq",UPN2_062,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),1929,20,1960,"0,0102040816",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,29",NA
"many samples, homopolymer 6C, low freq",UPN2_071,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),2668,44,2720,"0,0161764706",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,17",NA
"many samples, homopolymer 6C, low freq",UPN2_072,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),2450,29,2482,"0,0116841257",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,19",NA
"many samples, homopolymer 6C, low freq",UPN2_075,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),1829,26,1860,"0,0139784946",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,32",NA
"many samples, homopolymer 6C, low freq",UPN2_080,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),2029,27,2058,"0,0131195335",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,17",NA
"many samples, homopolymer 6C, low freq",UPN2_081,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),3065,34,3108,"0,0109395109",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,26",NA
"many samples, homopolymer 6C, low freq",UPN2_094,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),3916,45,3967,"0,0113435846",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,38",NA
"many samples, homopolymer 6C, low freq",UPN2_095,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),4167,58,4228,"0,01371807",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,36",NA
"many samples, homopolymer 6C, low freq",UPN2_096,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),3801,55,3861,"0,0142450142",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,42",NA
"many samples, homopolymer 6C, low freq",UPN2_097,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),4645,61,4714,"0,0129401782",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,31",NA
"many samples, homopolymer 6C, low freq",UPN2_098,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),3903,47,3955,"0,0118836915",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,41",NA
"many samples, homopolymer 6C, low freq",UPN2_100,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),3021,38,3066,"0,0123939987",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,39",NA
"many samples, homopolymer 6C, low freq",UPN2_101,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),3949,46,4006,"0,0114827758",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,43",NA
"many samples, homopolymer 6C, low freq",UPN2_102,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),3818,45,3870,"0,011627907",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,37",NA
"many samples, homopolymer 6C, low freq",UPN2_103,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),3293,34,3333,"0,0102010201",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,42",NA
"many samples, homopolymer 6C, low freq",UPN2_104,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),4016,50,4075,"0,0122699387",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,41",NA
"many samples, homopolymer 6C, low freq",UPN2_105,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),3384,38,3428,"0,0110851809",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,39",NA
"many samples, homopolymer 6C, low freq",UPN2_106,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),4589,57,4653,"0,0122501612",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,3",NA
"many samples, homopolymer 6C, low freq",UPN2_107,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),5957,71,6030,"0,011774461",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,36",NA
"many samples, homopolymer 6C, low freq",UPN2_108,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),5169,60,5239,"0,0114525673",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,36",NA
"many samples, homopolymer 6C, low freq",UPN2_109,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),4686,50,4742,"0,0105440742",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,27",NA
"many samples, homopolymer 6C, low freq",UPN2_111,2,25469529,GC,G,frameshift_variant(HIGH||ggc/|p.Gly413fs/c.1238delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),4543,53,4602,"0,0115167319",0,0,0,1,0,0,0,1,2,"0,1457",NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,33",NA
"inspected, many artifacts",UPN2_108,2,25469542,C,T,stop_gained(HIGH|NONSENSE|tGg/tAg|p.Trp409*/c.1226G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|T),5163,66,5234,"0,0126098586",0,0,0,0,1,0,0,1,2,NO,NO,COSM3991222,kidney,1,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,34","34,18"
"low bq, bad alignment, low freq, many artifacts",UPN2_062,2,25469548,A,C,missense_variant(MODERATE|MISSENSE|aTt/aGt|p.Ile407Ser/c.1220T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),1927,20,1959,"0,0102092905",0,0,0,0,1,0,0,0,1,NO,NO,COSM249800,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,1,Damaging,"25,76",15
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_041,2,25469566,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val401Gly/c.1202T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),13031,155,13385,"0,011580127",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,32",Tolerated,"21,28","14,97"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_089,2,25469566,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val401Gly/c.1202T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),3591,41,3648,"0,0112390351",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,32",Tolerated,"24,88","14,66"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_043,2,25469566,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val401Gly/c.1202T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),4842,53,4958,"0,0106897943",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,32",Tolerated,"21,65","14,13"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_044,2,25469566,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val401Gly/c.1202T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),1825,24,1867,"0,0128548473",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,32",Tolerated,"21,35","14,29"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,2,25469566,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val401Gly/c.1202T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),6593,89,6762,"0,0131617865",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,32",Tolerated,"20,96","14,9"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,2,25469566,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val401Gly/c.1202T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),9384,106,9602,"0,0110393668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,32",Tolerated,"21,26","14,25"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_048,2,25469566,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val401Gly/c.1202T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),10241,119,10473,"0,0113625513",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,32",Tolerated,"21,19","14,75"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,2,25469566,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val401Gly/c.1202T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),4959,55,5065,"0,0108588351",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,32",Tolerated,"21,37","14,33"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,2,25469566,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val401Gly/c.1202T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),6716,79,6851,"0,0115311633",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,32",Tolerated,"20,8","14,42"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,2,25469566,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val401Gly/c.1202T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),4865,59,4979,"0,011849769",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,32",Tolerated,"21,03","14,37"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,2,25469566,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val401Gly/c.1202T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),7114,80,7267,"0,0110086693",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,32",Tolerated,"20,84","14,59"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,2,25469566,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val401Gly/c.1202T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),4153,47,4255,"0,0110458284",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,32",Tolerated,"21,02","14,53"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_058,2,25469566,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val401Gly/c.1202T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),6909,82,7064,"0,011608154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,32",Tolerated,"21,34","14,95"
"low bq, bad alignment, many samples",UPN2_059,2,25469566,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val401Gly/c.1202T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),373,27,405,"0,0666666667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,32",Tolerated,"20,37",14
"low bq, bad alignment, many samples",UPN2_060,2,25469566,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val401Gly/c.1202T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),934,36,980,"0,0367346939",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,32",Tolerated,"19,86","15,61"
"low bq, bad alignment, many samples",UPN2_061,2,25469566,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val401Gly/c.1202T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),1533,89,1635,"0,0544342508",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,32",Tolerated,"19,76","15,01"
"low bq, bad alignment, many samples",UPN2_062,2,25469566,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val401Gly/c.1202T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),1861,80,1957,"0,0408788963",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,32",Tolerated,"19,83","14,09"
"low bq, bad alignment, many samples",UPN2_063,2,25469566,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val401Gly/c.1202T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),1317,55,1384,"0,0397398844",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,32",Tolerated,"20,18","15,09"
"low bq, bad alignment, many samples",UPN2_064,2,25469566,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val401Gly/c.1202T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),775,20,798,"0,0250626566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,32",Tolerated,"19,65","14,35"
"low bq, bad alignment, many samples",UPN2_065,2,25469566,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val401Gly/c.1202T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),546,25,572,"0,0437062937",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,32",Tolerated,"19,82","15,24"
"low bq, bad alignment, many samples",UPN2_068,2,25469566,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val401Gly/c.1202T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),499,32,536,"0,0597014925",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,32",Tolerated,"19,93",14
"low bq, bad alignment, many samples",UPN2_069,2,25469566,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val401Gly/c.1202T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),775,43,822,"0,0523114355",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,32",Tolerated,"20,2","14,88"
"low bq, bad alignment, many samples",UPN2_070,2,25469566,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val401Gly/c.1202T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),379,25,407,"0,0614250614",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,32",Tolerated,"19,61","14,52"
"low bq, bad alignment, many samples",UPN2_071,2,25469566,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val401Gly/c.1202T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),2571,116,2714,"0,0427413412",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,32",Tolerated,"19,6","14,73"
"low bq, bad alignment, many samples",UPN2_072,2,25469566,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val401Gly/c.1202T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),2328,135,2480,"0,0544354839",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,32",Tolerated,"20,02","14,6"
"low bq, bad alignment, many samples",UPN2_073,2,25469566,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val401Gly/c.1202T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),795,28,829,"0,0337756333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,32",Tolerated,"20,12",14
"low bq, bad alignment, many samples",UPN2_075,2,25469566,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val401Gly/c.1202T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),1765,79,1857,"0,042541734",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,32",Tolerated,"20,24","14,39"
"low bq, bad alignment, many samples",UPN2_076,2,25469566,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val401Gly/c.1202T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),980,46,1035,"0,0444444444",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,32",Tolerated,"19,81","14,15"
"low bq, bad alignment, many samples",UPN2_077,2,25469566,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val401Gly/c.1202T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),933,35,976,"0,0358606557",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,32",Tolerated,"20,18","15,2"
"low bq, bad alignment, many samples",UPN2_078,2,25469566,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val401Gly/c.1202T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),1858,72,1940,"0,0371134021",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,32",Tolerated,"20,58","14,61"
"low bq, bad alignment, many samples",UPN2_079,2,25469566,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val401Gly/c.1202T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),759,34,793,"0,0428751576",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,32",Tolerated,"19,51","15,38"
"low bq, bad alignment, many samples",UPN2_080,2,25469566,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val401Gly/c.1202T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),1954,84,2056,"0,0408560311",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,32",Tolerated,"20,1","14,31"
"low bq, bad alignment, many samples",UPN2_081,2,25469566,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val401Gly/c.1202T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),2932,145,3097,"0,0468195027",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,32",Tolerated,"19,98","14,86"
"low bq, bad alignment, many samples",UPN2_082,2,25469566,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val401Gly/c.1202T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),495,29,534,"0,0543071161",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,32",Tolerated,"20,6",14
"low bq, bad alignment, many samples",UPN2_083,2,25469566,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val401Gly/c.1202T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),879,44,932,"0,0472103004",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,32",Tolerated,"19,8",14
"low bq, bad alignment, many samples",UPN2_084,2,25469566,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val401Gly/c.1202T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),1021,61,1091,"0,0559120073",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,32",Tolerated,"19,76","14,66"
"low bq, bad alignment, many samples",UPN2_085,2,25469566,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val401Gly/c.1202T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),549,25,580,"0,0431034483",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,32",Tolerated,"19,44","14,72"
"low bq, bad alignment, many samples",UPN2_087,2,25469566,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val401Gly/c.1202T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),739,28,771,"0,0363164721",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,32",Tolerated,"20,12",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_105,2,25469566,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val401Gly/c.1202T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),3340,37,3392,"0,0109080189",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,32",Tolerated,"25,25","14,19"
"low bq, bad alignment, low freq, many artifacts",UPN2_109,2,25469566,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val401Gly/c.1202T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),4622,51,4700,"0,0108510638",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,32",Tolerated,"25,07","14,49"
"low freq, many artifacts",UPN2_041,2,25469566,A,G,missense_variant(MODERATE|MISSENSE|gTg/gCg|p.Val401Ala/c.1202T>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),13031,134,13385,"0,0100112066",0,0,0,0,0,0,0,1,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,42",Neutral,495,Tolerated,"21,28","32,59"
"low bq, low freq, many artifacts, many samples",UPN2_041,2,25469572,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val399Gly/c.1196T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),13172,148,13384,"0,0110579797",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,22",Neutral,8,Damaging,"27,03","18,51"
"low bq, bad alignment, many samples",UPN2_060,2,25469572,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val399Gly/c.1196T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),951,27,980,"0,0275510204",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,22",Neutral,8,Damaging,"25,48","14,26"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_013,2,25469572,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val399Gly/c.1196T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),1576,23,1604,"0,0143391521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,22",Neutral,8,Damaging,"25,45","14,87"
"low bq, bad alignment, many samples",UPN2_061,2,25469572,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val399Gly/c.1196T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),1578,49,1635,"0,029969419",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,22",Neutral,8,Damaging,"24,6","14,86"
"low bq, bad alignment, many samples",UPN2_062,2,25469572,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val399Gly/c.1196T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),1885,65,1957,"0,0332141032",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,22",Neutral,8,Damaging,"25,16","15,15"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,2,25469572,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val399Gly/c.1196T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),1350,29,1384,"0,0209537572",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,22",Neutral,8,Damaging,"25,42","14,48"
"low bq, bad alignment, many samples",UPN2_064,2,25469572,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val399Gly/c.1196T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),770,23,798,"0,0288220551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,22",Neutral,8,Damaging,"24,85",14
"low bq, bad alignment, many samples",UPN2_071,2,25469572,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val399Gly/c.1196T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),2642,64,2713,"0,0235901216",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,22",Neutral,8,Damaging,"25,22","15,95"
"low bq, bad alignment, many samples",UPN2_072,2,25469572,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val399Gly/c.1196T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),2398,74,2480,"0,0298387097",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,22",Neutral,8,Damaging,"24,59","14,61"
"low bq, bad alignment, many samples",UPN2_075,2,25469572,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val399Gly/c.1196T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),1799,49,1857,"0,0263866451",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,22",Neutral,8,Damaging,"25,97","15,16"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,2,25469572,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val399Gly/c.1196T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),1013,21,1035,"0,0202898551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,22",Neutral,8,Damaging,"24,74","14,86"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,2,25469572,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val399Gly/c.1196T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),951,20,976,"0,0204918033",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,22",Neutral,8,Damaging,"25,37",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,2,25469572,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val399Gly/c.1196T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),1892,40,1939,"0,0206291903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,22",Neutral,8,Damaging,"24,51","14,32"
"low bq, bad alignment, many samples",UPN2_079,2,25469572,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val399Gly/c.1196T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),765,21,792,"0,0265151515",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,22",Neutral,8,Damaging,"24,4","14,62"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,2,25469572,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val399Gly/c.1196T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),2005,45,2056,"0,0218871595",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,22",Neutral,8,Damaging,"24,88",14
"low bq, bad alignment, many samples",UPN2_081,2,25469572,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val399Gly/c.1196T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),2998,83,3097,"0,0268001292",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,22",Neutral,8,Damaging,"25,37","15,17"
"low bq, bad alignment, many samples",UPN2_083,2,25469572,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val399Gly/c.1196T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),909,22,932,"0,0236051502",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,22",Neutral,8,Damaging,"24,68","14,59"
"low bq, bad alignment, many samples",UPN2_084,2,25469572,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val399Gly/c.1196T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),1051,32,1090,"0,0293577982",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,22",Neutral,8,Damaging,"24,25","15,03"
"low bq, bad alignment",UPN2_087,2,25469572,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val399Gly/c.1196T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),742,25,771,"0,0324254215",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,22",Neutral,8,Damaging,"25,06","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25469577,C,G,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys397Asn/c.1191G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),1898,24,1924,"0,0124740125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,71,Tolerated,"29,67","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25469577,C,G,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys397Asn/c.1191G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),3189,34,3231,"0,0105230579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,71,Tolerated,"29,79",15
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25469577,C,G,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys397Asn/c.1191G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),3811,45,3863,"0,0116489775",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,71,Tolerated,"30,03",14
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25469577,C,G,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys397Asn/c.1191G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),2689,37,2731,"0,0135481509",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,71,Tolerated,"29,59","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25469577,C,G,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys397Asn/c.1191G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),1561,24,1585,"0,0151419558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,71,Tolerated,"29,96","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25469577,C,G,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys397Asn/c.1191G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),1604,25,1629,"0,0153468386",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,71,Tolerated,"29,78","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25469577,C,G,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys397Asn/c.1191G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),5264,81,5360,"0,0151119403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,71,Tolerated,"29,66","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25469577,C,G,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys397Asn/c.1191G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),4841,61,4905,"0,0124362895",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,71,Tolerated,"29,67","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25469577,C,G,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys397Asn/c.1191G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),1620,21,1647,"0,0127504554",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,71,Tolerated,"29,58",14
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25469577,C,G,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys397Asn/c.1191G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),3634,52,3691,"0,0140883229",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,71,Tolerated,"29,86","14,13"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25469577,C,G,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys397Asn/c.1191G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),2019,30,2055,"0,0145985401",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,71,Tolerated,"29,47","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25469577,C,G,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys397Asn/c.1191G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),1906,27,1936,"0,013946281",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,71,Tolerated,"29,92","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25469577,C,G,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys397Asn/c.1191G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),3777,48,3833,"0,0125228281",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,71,Tolerated,"29,76","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25469577,C,G,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys397Asn/c.1191G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),1546,24,1572,"0,0152671756",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,71,Tolerated,"29,75",14
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25469577,C,G,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys397Asn/c.1191G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),3994,67,4068,"0,0164700098",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,71,Tolerated,"29,57","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25469577,C,G,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys397Asn/c.1191G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),6042,82,6133,"0,0133702919",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,71,Tolerated,"29,72","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25469577,C,G,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys397Asn/c.1191G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),1804,33,1846,"0,0178764897",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,71,Tolerated,"29,94",15
"low bq, low freq, many artifacts",UPN2_087,2,25469577,C,G,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys397Asn/c.1191G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),1479,21,1516,"0,0138522427",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,71,Tolerated,"29,66","14,33"
"inspected, many artifacts",UPN2_079,2,25469585,T,C,missense_variant(MODERATE|MISSENSE|Act/Gct|p.Thr395Ala/c.1183A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),1540,20,1572,"0,0127226463",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,277",Tolerated,"30,46","31,6"
"inspected, many artifacts",UPN2_056,2,25469588,C,T,missense_variant(MODERATE|MISSENSE|Gac/Aac|p.Asp394Asn/c.1180G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|T),8398,91,8503,"0,0107021051",0,0,0,0,1,0,0,1,2,NO,NO,COSM4836021,cervix,1,NO,NO,NO,NO,NO,NO,"-1,05",Neutral,"0,089",Tolerated,"32,37","32,95"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25469589,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser393Arg/c.1179T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),1882,41,1940,"0,0211340206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,"0,01",Damaging,"27,76",14
"low bq, many samples",UPN2_061,2,25469589,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser393Arg/c.1179T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),3107,97,3231,"0,0300216651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,"0,01",Damaging,"27,68","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25469589,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser393Arg/c.1179T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),3775,84,3882,"0,0216383308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,"0,01",Damaging,"27,67","16,07"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25469589,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser393Arg/c.1179T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),2662,55,2730,"0,0201465201",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,"0,01",Damaging,"27,75","14,33"
"low bq, many samples",UPN2_064,2,25469589,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser393Arg/c.1179T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),1531,41,1586,"0,025851198",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,"0,01",Damaging,"27,9","15,07"
"low bq, many samples",UPN2_065,2,25469589,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser393Arg/c.1179T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),1097,26,1133,"0,0229479259",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,"0,01",Damaging,"27,71",14
"low bq, many samples",UPN2_068,2,25469589,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser393Arg/c.1179T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),1020,30,1068,"0,0280898876",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,"0,01",Damaging,"27,01","15,17"
"low bq, many samples",UPN2_069,2,25469589,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser393Arg/c.1179T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),1585,37,1633,"0,0226576852",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,"0,01",Damaging,"27,84","14,49"
"low bq, many samples",UPN2_070,2,25469589,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser393Arg/c.1179T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),769,34,808,"0,0420792079",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,"0,01",Damaging,"27,41","14,38"
"low bq, many samples",UPN2_071,2,25469589,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser393Arg/c.1179T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),5193,124,5367,"0,023104155",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,"0,01",Damaging,"27,57","15,13"
"low bq, many samples",UPN2_072,2,25469589,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser393Arg/c.1179T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),4766,133,4921,"0,027027027",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,"0,01",Damaging,"27,79","15,4"
"low bq, many samples",UPN2_073,2,25469589,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser393Arg/c.1179T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),1594,41,1648,"0,0248786408",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,"0,01",Damaging,"27,86","15,66"
"low bq, many samples",UPN2_075,2,25469589,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser393Arg/c.1179T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),3589,84,3694,"0,0227395777",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,"0,01",Damaging,"28,25","15,61"
"low bq, many samples",UPN2_076,2,25469589,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser393Arg/c.1179T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),1998,48,2065,"0,0232445521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,"0,01",Damaging,"27,8","14,94"
"low bq, many samples",UPN2_077,2,25469589,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser393Arg/c.1179T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),1873,50,1937,"0,0258131131",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,"0,01",Damaging,"27,81","15,14"
"low bq, many samples",UPN2_078,2,25469589,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser393Arg/c.1179T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),3729,95,3852,"0,024662513",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,"0,01",Damaging,"27,78","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25469589,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser393Arg/c.1179T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),1530,30,1571,"0,0190961171",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,"0,01",Damaging,"28,03","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25469589,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser393Arg/c.1179T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),3969,75,4084,"0,0183643487",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,"0,01",Damaging,"27,74","14,44"
"low bq, many samples",UPN2_081,2,25469589,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser393Arg/c.1179T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),5938,162,6136,"0,0264015645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,"0,01",Damaging,"27,81","14,93"
"low bq, many samples",UPN2_082,2,25469589,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser393Arg/c.1179T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),1021,28,1060,"0,0264150943",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,"0,01",Damaging,"28,11","20,79"
"low bq, many samples",UPN2_083,2,25469589,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser393Arg/c.1179T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),1782,46,1849,"0,0248783126",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,"0,01",Damaging,"27,59","15,13"
"low bq, many samples",UPN2_084,2,25469589,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser393Arg/c.1179T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),2091,67,2165,"0,0309468822",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,"0,01",Damaging,28,"15,31"
"low bq, many samples",UPN2_085,2,25469589,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser393Arg/c.1179T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),1118,26,1154,"0,0225303293",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,"0,01",Damaging,"27,72","15,04"
"low bq, many samples",UPN2_087,2,25469589,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser393Arg/c.1179T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),1454,39,1519,"0,025674786",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,"0,01",Damaging,"28,08","14,36"
low bq,UPN2_088,2,25469589,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser393Arg/c.1179T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),904,21,928,"0,0226293103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,"0,01",Damaging,"28,38",14
"low bq, low freq, many artifacts",UPN2_041,2,25469589,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser393Arg/c.1179T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|T),26232,273,26822,"0,0101782119",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,"0,01",Damaging,"28,13","23,83"
"inspected, many artifacts",UPN2_044,2,25469595,A,T,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp391Glu/c.1173T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|T),3629,67,3730,"0,0179624665",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,"0,163",Tolerated,"30,19","27,81"
"inspected, many artifacts",UPN2_044,2,25469604,G,T,missense_variant(MODERATE|MISSENSE|caC/caA|p.His388Gln/c.1164C>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|T),3674,49,3727,"0,0131473035",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,16",Neutral,"0,299",Tolerated,"32,56","29,82"
"low bq, low freq, many artifacts",UPN2_078,2,25469609,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys387Gly/c.1159T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),2645,39,2702,"0,0144337528",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,2,Damaging,"30,74","15,13"
"low bq, low freq, many artifacts",UPN2_078,2,25469611,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val386Gly/c.1157T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),2633,48,2700,"0,0177777778",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,402,Tolerated,"31,32","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_041,2,25469611,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val386Glu/c.1157T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|T),13240,142,13475,"0,0105380334",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,53",Neutral,292,Tolerated,"33,35","18,45"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,25469611,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val386Glu/c.1157T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|T),4804,54,4873,"0,0110814693",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,53",Neutral,292,Tolerated,"33,4","17,89"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,25469611,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val386Glu/c.1157T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|T),6612,76,6723,"0,0113044772",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,53",Neutral,292,Tolerated,"33,3","16,74"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,25469611,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val386Glu/c.1157T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|T),9341,96,9478,"0,0101287191",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,53",Neutral,292,Tolerated,"33,34","18,3"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,25469611,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val386Glu/c.1157T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|T),6002,66,6090,"0,0108374384",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,53",Neutral,292,Tolerated,"33,34",16
"low bq, low freq, many artifacts, many samples",UPN2_051,2,25469611,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val386Glu/c.1157T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|T),4942,55,5017,"0,0109627267",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,53",Neutral,292,Tolerated,"33,36","18,16"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,25469611,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val386Glu/c.1157T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|T),4833,60,4921,"0,0121926438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,53",Neutral,292,Tolerated,"33,5","20,07"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,25469611,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val386Glu/c.1157T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|T),7074,86,7189,"0,0119627208",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,53",Neutral,292,Tolerated,"33,41","17,26"
"low bq, low freq, many artifacts",UPN2_056,2,25469611,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val386Glu/c.1157T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|T),4204,44,4262,"0,0103237916",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,53",Neutral,292,Tolerated,"33,46",17
"low bq, low freq, many artifacts",UPN2_078,2,25469618,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe384Val/c.1150T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|C),2624,34,2697,"0,0126065999",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,17",Deleterious,25,Damaging,"30,24","14,79"
"low freq, many artifacts",UPN2_078,2,25469618,A,G,missense_variant(MODERATE|MISSENSE|Ttc/Ctc|p.Phe384Leu/c.1150T>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|G),2624,32,2697,"0,0118650352",0,0,0,0,0,0,0,1,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,55",Deleterious,43,Damaging,"30,24","34,75"
"low bq, low freq, many artifacts, many samples",UPN2_041,2,25469618,A,T,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe384Ile/c.1150T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|T),13252,136,13480,"0,0100890208",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,48",Deleterious,2,Damaging,"32,82","16,8"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,25469618,A,T,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe384Ile/c.1150T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|T),1831,23,1867,"0,0123192287",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,48",Deleterious,2,Damaging,"32,84","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,25469618,A,T,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe384Ile/c.1150T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|T),6617,70,6718,"0,0104197678",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,48",Deleterious,2,Damaging,"32,8","15,41"
"low bq, low freq, many artifacts, many samples",UPN2_032,2,25469618,A,T,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe384Ile/c.1150T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|T),1804,25,1834,"0,0136314068",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,48",Deleterious,2,Damaging,"33,71","17,36"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,25469618,A,T,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe384Ile/c.1150T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|T),6540,72,6650,"0,0108270677",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,48",Deleterious,2,Damaging,"32,77","15,92"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,25469618,A,T,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe384Ile/c.1150T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|T),9329,95,9478,"0,0100232116",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,48",Deleterious,2,Damaging,"32,87","16,81"
"low bq, low freq, many artifacts, many samples",UPN2_048,2,25469618,A,T,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe384Ile/c.1150T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|T),10265,107,10419,"0,0102696996",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,48",Deleterious,2,Damaging,"32,75","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,25469618,A,T,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe384Ile/c.1150T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|T),6957,76,7065,"0,0107572541",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,48",Deleterious,2,Damaging,"32,66","17,91"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,25469618,A,T,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe384Ile/c.1150T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|T),6641,68,6746,"0,0100800474",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,48",Deleterious,2,Damaging,"32,72","15,88"
"low bq, low freq, many artifacts",UPN2_056,2,25469618,A,T,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe384Ile/c.1150T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|T),4199,48,4262,"0,0112623182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,48",Deleterious,2,Damaging,"32,61","17,42"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,25469620,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu383Gln/c.1148T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|T),4805,52,4874,"0,0106688551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,41",Neutral,65,Tolerated,"33,9","16,52"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,25469620,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu383Gln/c.1148T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|T),1837,24,1868,"0,0128479657",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,41",Neutral,65,Tolerated,"33,83","16,38"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,25469620,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu383Gln/c.1148T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|T),6558,71,6650,"0,0106766917",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,41",Neutral,65,Tolerated,"33,88","22,04"
"low bq, low freq, many artifacts",UPN2_054,2,25469620,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu383Gln/c.1148T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|T),4837,53,4918,"0,0107767385",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,41",Neutral,65,Tolerated,"33,8","19,87"
"inspected, many artifacts",UPN2_078,2,25469633,G,A,missense_variant(MODERATE|MISSENSE|Cgc/Tgc|p.Arg379Cys/c.1135C>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|A),1892,24,1917,"0,0125195618",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"2,47E-005",NO,NO,"-6,79",Deleterious,0,Damaging,"34,52","33,79"
"inspected, many artifacts",UPN2_044,2,25469633,G,T,missense_variant(MODERATE|MISSENSE|Cgc/Agc|p.Arg379Ser/c.1135C>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|T),1832,33,1870,"0,0176470588",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,"0,01",Damaging,"34,94","31,48"
"low bq, low freq, many artifacts, many samples",UPN2_041,2,25469644,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val375Glu/c.1124T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|T),13289,138,13501,"0,0102214651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,235,Tolerated,"33,97","19,13"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,25469644,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val375Glu/c.1124T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|T),1834,22,1870,"0,0117647059",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,235,Tolerated,"33,97","17,64"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,25469644,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val375Glu/c.1124T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|10|T),6082,65,6182,"0,0105143966",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,235,Tolerated,"34,04","18,28"
inspected,UPN2_041,2,25469922,G,A,stop_gained(HIGH|NONSENSE|Cag/Tag|p.Gln374*/c.1120C>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|A),615,32,647,"0,0494590417",0,0,0,0,1,0,0,1,2,0,NO,NO,NO,O,NO,rs369109129,NO,"1,65E-005",NO,NO,NA,NA,NA,NA,"35,32","34,03"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,2,25469927,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val372Gly/c.1115T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2646,39,2689,"0,0145035329",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,0,Damaging,"23,1","14,72"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,2,25469927,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val372Gly/c.1115T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2877,40,2931,"0,0136472194",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,0,Damaging,"22,84","15,02"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,2,25469927,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val372Gly/c.1115T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3260,39,3315,"0,0117647059",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,0,Damaging,"23,75","14,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_070,2,25469927,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val372Gly/c.1115T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1558,24,1588,"0,0151133501",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,0,Damaging,"23,63","15,75"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,2,25469927,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val372Gly/c.1115T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2588,30,2627,"0,0114198706",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,0,Damaging,23,"14,47"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,2,25469927,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val372Gly/c.1115T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3476,46,3545,"0,0129760226",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,0,Damaging,"22,8","15,87"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_075,2,25469927,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val372Gly/c.1115T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2862,33,2902,"0,011371468",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,0,Damaging,"23,28","14,88"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,2,25469927,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val372Gly/c.1115T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1948,28,1986,"0,0140986908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,0,Damaging,"22,83","14,5"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,2,25469927,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val372Gly/c.1115T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2167,37,2209,"0,0167496605",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,0,Damaging,"23,03","14,95"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,2,25469927,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val372Gly/c.1115T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2941,39,2996,"0,0130173565",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,0,Damaging,"23,46","14,72"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,2,25469927,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val372Gly/c.1115T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3324,40,3379,"0,0118378218",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,0,Damaging,"22,88","15,25"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_081,2,25469927,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val372Gly/c.1115T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3820,42,3889,"0,0107996914",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,0,Damaging,"23,08","14,86"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,2,25469927,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val372Gly/c.1115T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2050,25,2085,"0,0119904077",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,0,Damaging,"22,33","15,64"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,2,25469927,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val372Gly/c.1115T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2777,40,2827,"0,0141492748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,0,Damaging,"23,49","14,98"
"low bq, bad alignment, low freq, many artifacts",UPN2_087,2,25469927,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val372Gly/c.1115T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1926,21,1957,"0,0107307103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,0,Damaging,"22,92","15,86"
"inspected, many artifacts",UPN2_044,2,25469927,A,G,missense_variant(MODERATE|MISSENSE|gTc/gCc|p.Val372Ala/c.1115T>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),2306,32,2348,"0,0136286201",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"0,19",Neutral,"0,731",Tolerated,"23,48","35,19"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25469960,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys361Thr/c.1082A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),2891,30,2930,"0,0102389078",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,05",Deleterious,98,Tolerated,"28,6",14
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25469960,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys361Thr/c.1082A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),3264,39,3315,"0,0117647059",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,05",Deleterious,98,Tolerated,"29,21","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,25469960,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys361Thr/c.1082A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),1556,21,1585,"0,0132492114",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,05",Deleterious,98,Tolerated,"28,98","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25469960,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys361Thr/c.1082A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),3492,39,3542,"0,0110107284",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,05",Deleterious,98,Tolerated,"28,71","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25469960,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys361Thr/c.1082A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),2353,25,2386,"0,0104777871",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,05",Deleterious,98,Tolerated,"29,33","15,56"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25469960,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys361Thr/c.1082A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),2947,35,2991,"0,011701772",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,05",Deleterious,98,Tolerated,"28,72","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25469960,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys361Thr/c.1082A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),1863,25,1894,"0,0131995776",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,05",Deleterious,98,Tolerated,"28,94","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25469960,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys361Thr/c.1082A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),2046,21,2084,"0,0100767754",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,05",Deleterious,98,Tolerated,"28,23","14,33"
"low bq, low freq, many artifacts",UPN2_084,2,25469960,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys361Thr/c.1082A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),2781,32,2821,"0,0113434952",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,05",Deleterious,98,Tolerated,"28,74",14
"inspected, many artifacts",UPN2_048,2,25469963,T,C,missense_variant(MODERATE|MISSENSE|aAc/aGc|p.Asn360Ser/c.1079A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2508,32,2554,"0,0125293657",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,037",Damaging,"33,15","34,59"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,2,25469967,A,C,missense_variant(MODERATE|MISSENSE|Tac/Gac|p.Tyr359Asp/c.1075T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2943,36,2990,"0,0120401338",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,66",Deleterious,38,Damaging,"24,22","14,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,2,25469967,A,C,missense_variant(MODERATE|MISSENSE|Tac/Gac|p.Tyr359Asp/c.1075T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2776,32,2821,"0,0113434952",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,66",Deleterious,38,Damaging,"23,99","14,69"
"low bq, bad alignment, many samples",UPN2_059,2,25469981,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe354Cys/c.1061T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1381,84,1469,"0,0571817563",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,58",Deleterious,0,Damaging,"20,82","15,1"
"low bq, bad alignment, many samples",UPN2_060,2,25469981,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe354Cys/c.1061T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2062,83,2156,"0,0384972171",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,58",Deleterious,0,Damaging,"21,21","14,4"
"low bq, bad alignment, many samples",UPN2_061,2,25469981,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe354Cys/c.1061T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2547,119,2684,"0,0443368107",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,58",Deleterious,0,Damaging,"20,25","14,56"
"low bq, bad alignment, many samples",UPN2_062,2,25469981,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe354Cys/c.1061T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2772,139,2927,"0,0474888965",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,58",Deleterious,0,Damaging,"20,16","14,76"
"low bq, bad alignment, many samples",UPN2_063,2,25469981,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe354Cys/c.1061T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3145,146,3308,"0,0441354293",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,58",Deleterious,0,Damaging,"21,06","14,45"
"low bq, bad alignment, many samples",UPN2_064,2,25469981,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe354Cys/c.1061T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1901,87,2005,"0,0433915212",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,58",Deleterious,0,Damaging,"21,06","14,36"
"low bq, bad alignment, many samples",UPN2_065,2,25469981,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe354Cys/c.1061T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),979,42,1025,"0,0409756098",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,58",Deleterious,0,Damaging,"20,85","14,9"
"low bq, bad alignment, many samples",UPN2_066,2,25469981,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe354Cys/c.1061T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),769,33,804,"0,0410447761",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,58",Deleterious,0,Damaging,"21,02","14,88"
"low bq, bad alignment, many samples",UPN2_067,2,25469981,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe354Cys/c.1061T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1165,57,1227,"0,0464547677",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,58",Deleterious,0,Damaging,"21,5","14,12"
"low bq, bad alignment, many samples",UPN2_068,2,25469981,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe354Cys/c.1061T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1460,68,1533,"0,044357469",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,58",Deleterious,0,Damaging,"20,09","14,66"
"low bq, bad alignment, many samples",UPN2_069,2,25469981,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe354Cys/c.1061T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3011,168,3189,"0,0526810913",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,58",Deleterious,0,Damaging,"20,64","14,56"
"low bq, bad alignment, many samples",UPN2_070,2,25469981,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe354Cys/c.1061T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1495,84,1583,"0,0530638029",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,58",Deleterious,0,Damaging,"20,75","14,24"
"low bq, bad alignment, many samples",UPN2_071,2,25469981,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe354Cys/c.1061T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2483,121,2619,"0,04620084",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,58",Deleterious,0,Damaging,"20,54","15,12"
"low bq, bad alignment, many samples",UPN2_072,2,25469981,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe354Cys/c.1061T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3362,162,3537,"0,0458015267",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,58",Deleterious,0,Damaging,"20,36","14,94"
"low bq, bad alignment, many samples",UPN2_073,2,25469981,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe354Cys/c.1061T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2285,91,2385,"0,0381551363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,58",Deleterious,0,Damaging,"20,94","14,36"
"low bq, bad alignment, many samples",UPN2_074,2,25469981,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe354Cys/c.1061T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1015,38,1058,"0,0359168242",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,58",Deleterious,0,Damaging,"21,25","14,34"
"low bq, bad alignment, many samples",UPN2_075,2,25469981,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe354Cys/c.1061T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2794,92,2897,"0,03175699",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,58",Deleterious,0,Damaging,"20,77","14,29"
"low bq, bad alignment, many samples",UPN2_076,2,25469981,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe354Cys/c.1061T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1870,101,1981,"0,0509843513",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,58",Deleterious,0,Damaging,"20,1","14,94"
"low bq, bad alignment, many samples",UPN2_077,2,25469981,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe354Cys/c.1061T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2088,109,2205,"0,0494331066",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,58",Deleterious,0,Damaging,"20,3","14,96"
"low bq, bad alignment, many samples",UPN2_078,2,25469981,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe354Cys/c.1061T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2820,150,2982,"0,0503018109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,58",Deleterious,0,Damaging,"20,09","14,73"
"low bq, bad alignment, many samples",UPN2_079,2,25469981,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe354Cys/c.1061T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1792,87,1888,"0,0460805085",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,58",Deleterious,0,Damaging,"20,77","14,45"
"low bq, bad alignment, many samples",UPN2_080,2,25469981,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe354Cys/c.1061T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3188,164,3372,"0,0486358244",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,58",Deleterious,0,Damaging,"20,69","14,59"
"low bq, bad alignment, many samples",UPN2_081,2,25469981,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe354Cys/c.1061T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3690,175,3879,"0,0451147203",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,58",Deleterious,0,Damaging,"20,69","14,31"
"low bq, bad alignment, many samples",UPN2_082,2,25469981,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe354Cys/c.1061T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1755,85,1847,"0,0460205739",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,58",Deleterious,0,Damaging,"21,38","14,68"
"low bq, bad alignment, many samples",UPN2_083,2,25469981,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe354Cys/c.1061T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1954,120,2080,"0,0576923077",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,58",Deleterious,0,Damaging,"19,96","14,29"
"low bq, bad alignment, many samples",UPN2_084,2,25469981,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe354Cys/c.1061T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2654,158,2817,"0,0560880369",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,58",Deleterious,0,Damaging,"20,49","14,78"
"low bq, bad alignment, many samples",UPN2_085,2,25469981,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe354Cys/c.1061T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1254,61,1316,"0,0463525836",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,58",Deleterious,0,Damaging,"20,19",14
"low bq, bad alignment, many samples",UPN2_086,2,25469981,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe354Cys/c.1061T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),767,41,813,"0,0504305043",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,58",Deleterious,0,Damaging,"19,92","14,88"
"low bq, bad alignment, many samples",UPN2_087,2,25469981,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe354Cys/c.1061T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1853,91,1953,"0,0465949821",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,58",Deleterious,0,Damaging,"20,31","14,55"
"low bq, bad alignment",UPN2_088,2,25469981,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe354Cys/c.1061T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1242,68,1319,"0,0515542077",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,58",Deleterious,0,Damaging,"21,22","14,74"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_089,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3827,40,3893,"0,0102748523",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"17,26",14
"low bq, bad alignment, many samples",UPN2_059,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1374,78,1469,"0,0530973451",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"16,47","14,17"
"low bq, bad alignment, many samples",UPN2_060,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2012,124,2156,"0,0575139147",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"16,24","14,35"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_091,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3519,41,3580,"0,011452514",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"17,02",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_092,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2088,23,2120,"0,0108490566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"17,21","15,35"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_093,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2829,30,2884,"0,0104022191",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"17,42","15,17"
"low bq, bad alignment, many samples",UPN2_061,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2513,139,2683,"0,051807678",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"16,51","14,26"
"low bq, bad alignment, many samples",UPN2_062,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2721,183,2925,"0,0625641026",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,16,"14,28"
"low bq, bad alignment, many samples",UPN2_063,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3073,193,3308,"0,0583434099",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"16,11","14,51"
"low bq, bad alignment, many samples",UPN2_064,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1882,108,2005,"0,0538653367",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"16,16","14,23"
"low bq, bad alignment, many samples",UPN2_065,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),960,55,1025,"0,0536585366",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"15,98","14,24"
"low bq, bad alignment, many samples",UPN2_066,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),750,44,804,"0,0547263682",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"16,7","14,16"
"low bq, bad alignment, many samples",UPN2_067,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1147,65,1227,"0,0529747351",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"16,68",14
"low bq, bad alignment, many samples",UPN2_068,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1434,89,1533,"0,0580560992",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"15,81","14,36"
"low bq, bad alignment, many samples",UPN2_069,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2970,176,3187,"0,0552243489",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"16,28","14,56"
"low bq, bad alignment, many samples",UPN2_070,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1456,105,1581,"0,0664136622",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"16,02","14,07"
"low bq, bad alignment, many samples",UPN2_071,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2449,143,2617,"0,0546427207",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"16,13","14,17"
"low bq, bad alignment, many samples",UPN2_072,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3309,203,3536,"0,0574095023",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"16,31","14,23"
"low bq, bad alignment, many samples",UPN2_073,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2248,113,2384,"0,0473993289",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"16,21","14,18"
"low bq, bad alignment, many samples",UPN2_074,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),990,60,1058,"0,056710775",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"16,98",14
"low bq, bad alignment, many samples",UPN2_075,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2709,157,2897,"0,0541939938",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"16,4","14,16"
"low bq, bad alignment, many samples",UPN2_076,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1853,111,1980,"0,0560606061",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"16,12","14,18"
"low bq, bad alignment, many samples",UPN2_077,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2065,122,2204,"0,055353902",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"15,9","14,2"
"low bq, bad alignment, many samples",UPN2_079,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1776,88,1886,"0,046659597",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"16,37","14,28"
"low bq, bad alignment, many samples",UPN2_080,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3144,192,3364,"0,0570749108",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"16,14","14,34"
"low bq, bad alignment, many samples",UPN2_081,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3641,192,3876,"0,0495356037",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"16,16","14,1"
"low bq, bad alignment, many samples",UPN2_082,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1741,90,1845,"0,0487804878",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"16,31","14,22"
"low bq, bad alignment, many samples",UPN2_083,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1940,117,2080,"0,05625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"15,8","14,34"
"low bq, bad alignment, many samples",UPN2_084,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2604,183,2816,"0,0649857955",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"15,97","14,17"
"low bq, bad alignment, many samples",UPN2_085,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1232,71,1316,"0,0539513678",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"16,31",14
"low bq, bad alignment, many samples",UPN2_086,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),758,52,813,"0,0639606396",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"16,5",14
"low bq, bad alignment, many samples",UPN2_087,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1830,108,1952,"0,0553278689",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"16,11","14,35"
"low bq, bad alignment, many samples",UPN2_088,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1255,50,1319,"0,0379075057",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"16,68",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_094,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4258,51,4328,"0,0117837338",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"17,22","14,78"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_095,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4138,55,4217,"0,0130424472",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"16,99","14,53"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_097,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4847,60,4933,"0,012162984",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"17,12","14,23"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_098,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4141,47,4211,"0,0111612444",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"16,99","14,62"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_099,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1970,29,2006,"0,0144566301",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"17,09","14,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_100,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3264,36,3323,"0,0108335841",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"16,98",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_102,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3939,49,4007,"0,0122286",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"17,14","14,27"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_103,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3443,38,3503,"0,0108478447",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"16,87",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_104,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4273,52,4341,"0,0119788067",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"16,88",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_106,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),5044,58,5134,"0,0112972341",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"17,34",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_107,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),6774,70,6895,"0,0101522843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"17,15","14,51"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_108,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),5395,65,5487,"0,0118461819",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"17,23","14,11"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_109,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),5221,55,5310,"0,0103578154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"17,06",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_110,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),5068,52,5150,"0,0100970874",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"17,28",14
"low bq, bad alignment, low freq, many artifacts",UPN2_111,2,25469982,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe354Val/c.1060T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4610,63,4699,"0,0134071079",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,65",Deleterious,2,Damaging,"17,19","14,76"
"low bq, bad alignment, low freq, many artifacts",UPN2_045,2,25469982,A,G,missense_variant(MODERATE|MISSENSE|Ttc/Ctc|p.Phe354Leu/c.1060T>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),7483,81,7638,"0,0106048704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,72",Deleterious,29,Damaging,"17,64","25,57"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_090,2,25469986,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser352Arg/c.1056T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3393,39,3446,"0,0113174695",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,02",Neutral,127,Tolerated,"19,44","14,46"
"low bq, bad alignment, many samples",UPN2_059,2,25469986,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser352Arg/c.1056T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1380,78,1469,"0,0530973451",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,02",Neutral,127,Tolerated,"17,58","14,55"
"low bq, bad alignment, many samples",UPN2_060,2,25469986,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser352Arg/c.1056T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2049,95,2156,"0,0440630798",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,02",Neutral,127,Tolerated,"17,36","14,15"
"low bq, bad alignment, many samples",UPN2_061,2,25469986,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser352Arg/c.1056T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2517,137,2683,"0,0510622438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,02",Neutral,127,Tolerated,"17,34","15,19"
"low bq, bad alignment, many samples",UPN2_064,2,25469986,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser352Arg/c.1056T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1910,85,2005,"0,042394015",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,02",Neutral,127,Tolerated,"17,42",14
"low bq, bad alignment, many samples",UPN2_065,2,25469986,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser352Arg/c.1056T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),976,43,1025,"0,0419512195",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,02",Neutral,127,Tolerated,"17,38","15,23"
"low bq, bad alignment, many samples",UPN2_066,2,25469986,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser352Arg/c.1056T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),758,35,804,"0,0435323383",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,02",Neutral,127,Tolerated,"17,29","14,2"
"low bq, bad alignment, many samples",UPN2_067,2,25469986,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser352Arg/c.1056T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1163,49,1227,"0,0399348003",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,02",Neutral,127,Tolerated,"17,88","14,14"
"low bq, bad alignment, many samples",UPN2_068,2,25469986,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser352Arg/c.1056T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1452,78,1533,"0,0508806262",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,02",Neutral,127,Tolerated,"17,42",14
"low bq, bad alignment, many samples",UPN2_069,2,25469986,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser352Arg/c.1056T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2984,171,3187,"0,0536554754",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,02",Neutral,127,Tolerated,"17,66","14,48"
"low bq, bad alignment, many samples",UPN2_070,2,25469986,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser352Arg/c.1056T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1487,80,1581,"0,0506008855",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,02",Neutral,127,Tolerated,"17,55","14,16"
"low bq, bad alignment, many samples",UPN2_071,2,25469986,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser352Arg/c.1056T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2477,120,2616,"0,0458715596",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,02",Neutral,127,Tolerated,"17,68","14,57"
"low bq, bad alignment, many samples",UPN2_072,2,25469986,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser352Arg/c.1056T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3339,162,3535,"0,0458274399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,02",Neutral,127,Tolerated,"17,29",14
"low bq, bad alignment, many samples",UPN2_073,2,25469986,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser352Arg/c.1056T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2256,113,2384,"0,0473993289",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,02",Neutral,127,Tolerated,"17,59","14,12"
"low bq, bad alignment, many samples",UPN2_074,2,25469986,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser352Arg/c.1056T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),991,52,1058,"0,0491493384",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,02",Neutral,127,Tolerated,"17,7","14,56"
"low bq, bad alignment, many samples",UPN2_075,2,25469986,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser352Arg/c.1056T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2743,129,2896,"0,0445441989",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,02",Neutral,127,Tolerated,"17,49","14,65"
"low bq, bad alignment, many samples",UPN2_076,2,25469986,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser352Arg/c.1056T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1861,97,1980,"0,048989899",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,02",Neutral,127,Tolerated,"17,19","14,33"
"low bq, bad alignment, many samples",UPN2_077,2,25469986,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser352Arg/c.1056T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2061,118,2203,"0,0535633227",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,02",Neutral,127,Tolerated,"17,15","14,52"
"low bq, bad alignment, many samples",UPN2_079,2,25469986,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser352Arg/c.1056T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1790,82,1886,"0,0434782609",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,02",Neutral,127,Tolerated,"17,64","14,6"
"low bq, bad alignment, many samples",UPN2_080,2,25469986,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser352Arg/c.1056T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3179,152,3364,"0,0451843044",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,02",Neutral,127,Tolerated,"17,48","14,58"
"low bq, bad alignment, many samples",UPN2_082,2,25469986,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser352Arg/c.1056T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1733,91,1845,"0,0493224932",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,02",Neutral,127,Tolerated,"17,71","14,44"
"low bq, bad alignment, many samples",UPN2_085,2,25469986,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser352Arg/c.1056T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1227,75,1316,"0,0569908815",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,02",Neutral,127,Tolerated,"17,43","14,09"
"low bq, bad alignment, many samples",UPN2_086,2,25469986,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser352Arg/c.1056T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),764,42,812,"0,0517241379",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,02",Neutral,127,Tolerated,"17,84","14,48"
"low bq, bad alignment, many samples",UPN2_087,2,25469986,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser352Arg/c.1056T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1859,78,1952,"0,0399590164",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,02",Neutral,127,Tolerated,"17,36","14,17"
"low bq, bad alignment, many samples",UPN2_088,2,25469986,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser352Arg/c.1056T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1257,54,1319,"0,0409401061",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,02",Neutral,127,Tolerated,18,14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_095,2,25469986,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser352Arg/c.1056T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4147,49,4217,"0,0116196348",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,02",Neutral,127,Tolerated,"19,06","14,82"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_096,2,25469986,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser352Arg/c.1056T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3883,40,3942,"0,0101471334",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,02",Neutral,127,Tolerated,"19,08",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_097,2,25469986,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser352Arg/c.1056T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4852,54,4933,"0,0109466856",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,02",Neutral,127,Tolerated,"19,29",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_101,2,25469986,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser352Arg/c.1056T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3731,44,3798,"0,0115850448",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,02",Neutral,127,Tolerated,"19,23","14,5"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_104,2,25469986,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser352Arg/c.1056T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4274,51,4341,"0,0117484451",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,02",Neutral,127,Tolerated,"18,9","14,61"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_106,2,25469986,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser352Arg/c.1056T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),5046,53,5132,"0,0103273578",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,02",Neutral,127,Tolerated,"19,2",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_107,2,25469986,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser352Arg/c.1056T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),6790,70,6895,"0,0101522843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,02",Neutral,127,Tolerated,"19,21","14,41"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_110,2,25469986,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser352Arg/c.1056T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),5070,59,5150,"0,0114563107",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,02",Neutral,127,Tolerated,"19,34",14
"low bq, bad alignment, low freq, many artifacts",UPN2_111,2,25469986,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser352Arg/c.1056T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4622,55,4699,"0,011704618",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,02",Neutral,127,Tolerated,"19,03","14,24"
"inspected, many artifacts",UPN2_048,2,25469990,C,T,missense_variant(MODERATE|MISSENSE|tGc/tAc|p.Cys351Tyr/c.1052G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|T),2490,59,2550,"0,0231372549",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,47",Neutral,"0,812",Tolerated,"33,56","31,49"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,2,25469992,A,C,missense_variant(MODERATE|MISSENSE|ttT/ttG|p.Phe350Leu/c.1050T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2868,32,2921,"0,0109551523",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,41",Deleterious,"0,05",Damaging,"21,65","14,22"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,2,25469992,A,C,missense_variant(MODERATE|MISSENSE|ttT/ttG|p.Phe350Leu/c.1050T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1973,21,2004,"0,0104790419",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,41",Deleterious,"0,05",Damaging,"22,41","14,86"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_069,2,25469992,A,C,missense_variant(MODERATE|MISSENSE|ttT/ttG|p.Phe350Leu/c.1050T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3136,38,3184,"0,0119346734",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,41",Deleterious,"0,05",Damaging,"22,17","15,61"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_070,2,25469992,A,C,missense_variant(MODERATE|MISSENSE|ttT/ttG|p.Phe350Leu/c.1050T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1551,24,1580,"0,0151898734",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,41",Deleterious,"0,05",Damaging,"22,15","14,29"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,2,25469992,A,C,missense_variant(MODERATE|MISSENSE|ttT/ttG|p.Phe350Leu/c.1050T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3461,40,3533,"0,0113218228",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,41",Deleterious,"0,05",Damaging,"21,86",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,2,25469992,A,C,missense_variant(MODERATE|MISSENSE|ttT/ttG|p.Phe350Leu/c.1050T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2342,27,2383,"0,011330256",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,41",Deleterious,"0,05",Damaging,"22,45",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_075,2,25469992,A,C,missense_variant(MODERATE|MISSENSE|ttT/ttG|p.Phe350Leu/c.1050T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2848,35,2893,"0,012098168",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,41",Deleterious,"0,05",Damaging,"22,63","14,2"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,2,25469992,A,C,missense_variant(MODERATE|MISSENSE|ttT/ttG|p.Phe350Leu/c.1050T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1948,20,1979,"0,0101061142",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,41",Deleterious,"0,05",Damaging,"21,9",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,2,25469992,A,C,missense_variant(MODERATE|MISSENSE|ttT/ttG|p.Phe350Leu/c.1050T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2152,42,2203,"0,0190649115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,41",Deleterious,"0,05",Damaging,"21,98","14,17"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,2,25469992,A,C,missense_variant(MODERATE|MISSENSE|ttT/ttG|p.Phe350Leu/c.1050T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2928,34,2975,"0,0114285714",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,41",Deleterious,"0,05",Damaging,"21,43",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,2,25469992,A,C,missense_variant(MODERATE|MISSENSE|ttT/ttG|p.Phe350Leu/c.1050T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2034,25,2078,"0,0120307988",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,41",Deleterious,"0,05",Damaging,"21,65",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,2,25469992,A,C,missense_variant(MODERATE|MISSENSE|ttT/ttG|p.Phe350Leu/c.1050T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2773,29,2814,"0,0103056148",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,41",Deleterious,"0,05",Damaging,"21,92","15,38"
"low bq, bad alignment, low freq, many artifacts",UPN2_087,2,25469992,A,C,missense_variant(MODERATE|MISSENSE|ttT/ttG|p.Phe350Leu/c.1050T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1919,21,1950,"0,0107692308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,41",Deleterious,"0,05",Damaging,"22,08","14,33"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_089,2,25469993,A,C,missense_variant(MODERATE|MISSENSE|tTt/tGt|p.Phe350Cys/c.1049T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3839,40,3890,"0,0102827763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,13",Deleterious,1,Damaging,"20,7","14,55"
"low bq, bad alignment, many samples",UPN2_059,2,25469993,A,C,missense_variant(MODERATE|MISSENSE|tTt/tGt|p.Phe350Cys/c.1049T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1389,74,1467,"0,0504430811",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,13",Deleterious,1,Damaging,"18,81","14,28"
"low bq, bad alignment, many samples",UPN2_060,2,25469993,A,C,missense_variant(MODERATE|MISSENSE|tTt/tGt|p.Phe350Cys/c.1049T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2040,105,2153,"0,0487691593",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,13",Deleterious,1,Damaging,"18,97","14,64"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_092,2,25469993,A,C,missense_variant(MODERATE|MISSENSE|tTt/tGt|p.Phe350Cys/c.1049T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2091,22,2120,"0,0103773585",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,13",Deleterious,1,Damaging,"21,23","18,82"
"low bq, bad alignment, many samples",UPN2_062,2,25469993,A,C,missense_variant(MODERATE|MISSENSE|tTt/tGt|p.Phe350Cys/c.1049T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2741,153,2922,"0,0523613963",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,13",Deleterious,1,Damaging,18,"14,09"
"low bq, bad alignment, many samples",UPN2_064,2,25469993,A,C,missense_variant(MODERATE|MISSENSE|tTt/tGt|p.Phe350Cys/c.1049T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1904,94,2004,"0,0469061876",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,13",Deleterious,1,Damaging,"18,59","14,5"
"low bq, bad alignment, many samples",UPN2_065,2,25469993,A,C,missense_variant(MODERATE|MISSENSE|tTt/tGt|p.Phe350Cys/c.1049T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),973,48,1025,"0,0468292683",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,13",Deleterious,1,Damaging,"18,22",14
"low bq, bad alignment, many samples",UPN2_066,2,25469993,A,C,missense_variant(MODERATE|MISSENSE|tTt/tGt|p.Phe350Cys/c.1049T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),756,40,803,"0,0498132005",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,13",Deleterious,1,Damaging,"18,94","15,38"
"low bq, bad alignment, many samples",UPN2_067,2,25469993,A,C,missense_variant(MODERATE|MISSENSE|tTt/tGt|p.Phe350Cys/c.1049T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1143,73,1226,"0,05954323",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,13",Deleterious,1,Damaging,"18,79",14
"low bq, bad alignment, many samples",UPN2_068,2,25469993,A,C,missense_variant(MODERATE|MISSENSE|tTt/tGt|p.Phe350Cys/c.1049T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1446,77,1531,"0,0502939255",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,13",Deleterious,1,Damaging,"18,11","14,26"
"low bq, bad alignment, many samples",UPN2_070,2,25469993,A,C,missense_variant(MODERATE|MISSENSE|tTt/tGt|p.Phe350Cys/c.1049T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1462,110,1580,"0,0696202532",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,13",Deleterious,1,Damaging,"18,55","14,13"
"low bq, bad alignment, many samples",UPN2_071,2,25469993,A,C,missense_variant(MODERATE|MISSENSE|tTt/tGt|p.Phe350Cys/c.1049T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2472,132,2611,"0,0505553428",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,13",Deleterious,1,Damaging,"18,81","14,57"
"low bq, bad alignment, many samples",UPN2_074,2,25469993,A,C,missense_variant(MODERATE|MISSENSE|tTt/tGt|p.Phe350Cys/c.1049T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),997,48,1057,"0,0454115421",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,13",Deleterious,1,Damaging,"18,77",14
"low bq, bad alignment, many samples",UPN2_075,2,25469993,A,C,missense_variant(MODERATE|MISSENSE|tTt/tGt|p.Phe350Cys/c.1049T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2738,134,2894,"0,0463026952",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,13",Deleterious,1,Damaging,"18,83","14,35"
"low bq, bad alignment, many samples",UPN2_076,2,25469993,A,C,missense_variant(MODERATE|MISSENSE|tTt/tGt|p.Phe350Cys/c.1049T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1857,114,1979,"0,0576048509",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,13",Deleterious,1,Damaging,"18,15","14,18"
"low bq, bad alignment, many samples",UPN2_077,2,25469993,A,C,missense_variant(MODERATE|MISSENSE|tTt/tGt|p.Phe350Cys/c.1049T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2072,119,2203,"0,0540172492",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,13",Deleterious,1,Damaging,"18,48","14,29"
"low bq, bad alignment, many samples",UPN2_078,2,25469993,A,C,missense_variant(MODERATE|MISSENSE|tTt/tGt|p.Phe350Cys/c.1049T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2791,167,2973,"0,0561722166",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,13",Deleterious,1,Damaging,"18,43","14,41"
"low bq, bad alignment, many samples",UPN2_079,2,25469993,A,C,missense_variant(MODERATE|MISSENSE|tTt/tGt|p.Phe350Cys/c.1049T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1752,121,1884,"0,0642250531",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,13",Deleterious,1,Damaging,"18,99","14,22"
"low bq, bad alignment, many samples",UPN2_080,2,25469993,A,C,missense_variant(MODERATE|MISSENSE|tTt/tGt|p.Phe350Cys/c.1049T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3170,178,3363,"0,0529289325",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,13",Deleterious,1,Damaging,"18,39","14,66"
"low bq, bad alignment, many samples",UPN2_081,2,25469993,A,C,missense_variant(MODERATE|MISSENSE|tTt/tGt|p.Phe350Cys/c.1049T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3654,202,3872,"0,0521694215",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,13",Deleterious,1,Damaging,"18,4","14,14"
"low bq, bad alignment, many samples",UPN2_082,2,25469993,A,C,missense_variant(MODERATE|MISSENSE|tTt/tGt|p.Phe350Cys/c.1049T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1723,113,1843,"0,0613130765",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,13",Deleterious,1,Damaging,"18,83","14,48"
"low bq, bad alignment, many samples",UPN2_085,2,25469993,A,C,missense_variant(MODERATE|MISSENSE|tTt/tGt|p.Phe350Cys/c.1049T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1246,68,1316,"0,0516717325",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,13",Deleterious,1,Damaging,"18,51",14
"low bq, bad alignment, many samples",UPN2_086,2,25469993,A,C,missense_variant(MODERATE|MISSENSE|tTt/tGt|p.Phe350Cys/c.1049T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),757,48,812,"0,0591133005",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,13",Deleterious,1,Damaging,"18,85","14,46"
"low bq, bad alignment, many samples",UPN2_087,2,25469993,A,C,missense_variant(MODERATE|MISSENSE|tTt/tGt|p.Phe350Cys/c.1049T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1836,101,1950,"0,0517948718",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,13",Deleterious,1,Damaging,"18,4","14,28"
"low bq, bad alignment, many samples",UPN2_088,2,25469993,A,C,missense_variant(MODERATE|MISSENSE|tTt/tGt|p.Phe350Cys/c.1049T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1245,66,1319,"0,0500379075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,13",Deleterious,1,Damaging,"19,28",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_095,2,25469993,A,C,missense_variant(MODERATE|MISSENSE|tTt/tGt|p.Phe350Cys/c.1049T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4145,49,4212,"0,0116334283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,13",Deleterious,1,Damaging,"20,44","15,67"
"low bq, bad alignment, low freq, many artifacts",UPN2_102,2,25469993,A,C,missense_variant(MODERATE|MISSENSE|tTt/tGt|p.Phe350Cys/c.1049T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3943,42,4005,"0,0104868914",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,13",Deleterious,1,Damaging,"20,77","14,33"
"inspected, many artifacts",UPN2_044,2,25469994,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe350Val/c.1048T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2261,53,2338,"0,0226689478",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,19",Deleterious,"0,004",Damaging,"20,15","31,49"
"low bq, bad alignment, many samples",UPN2_059,2,25469994,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe350Val/c.1048T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1401,60,1467,"0,0408997955",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,19",Deleterious,4,Damaging,"17,33","14,22"
"low bq, bad alignment, many samples",UPN2_060,2,25469994,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe350Val/c.1048T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2049,94,2153,"0,0436600093",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,19",Deleterious,4,Damaging,"17,54","14,5"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_092,2,25469994,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe350Val/c.1048T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2080,27,2119,"0,0127418594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,19",Deleterious,4,Damaging,"19,13","14,81"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_093,2,25469994,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe350Val/c.1048T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2828,38,2883,"0,0131807145",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,19",Deleterious,4,Damaging,"19,01","15,24"
"low bq, bad alignment, many samples",UPN2_064,2,25469994,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe350Val/c.1048T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1895,96,2004,"0,0479041916",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,19",Deleterious,4,Damaging,"17,33","14,49"
"low bq, bad alignment, many samples",UPN2_065,2,25469994,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe350Val/c.1048T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),944,69,1025,"0,0673170732",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,19",Deleterious,4,Damaging,"17,16",14
"low bq, bad alignment, many samples",UPN2_066,2,25469994,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe350Val/c.1048T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),765,32,803,"0,0398505604",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,19",Deleterious,4,Damaging,"17,57","15,09"
"low bq, bad alignment, many samples",UPN2_067,2,25469994,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe350Val/c.1048T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1165,52,1226,"0,0424143556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,19",Deleterious,4,Damaging,"17,65","14,25"
"low bq, bad alignment, many samples",UPN2_068,2,25469994,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe350Val/c.1048T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1435,79,1530,"0,0516339869",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,19",Deleterious,4,Damaging,"17,14",14
"low bq, bad alignment, many samples",UPN2_070,2,25469994,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe350Val/c.1048T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1497,77,1580,"0,0487341772",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,19",Deleterious,4,Damaging,"17,04","14,09"
"low bq, bad alignment, many samples",UPN2_071,2,25469994,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe350Val/c.1048T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2453,136,2609,"0,0521272518",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,19",Deleterious,4,Damaging,"17,33","14,16"
"low bq, bad alignment, many samples",UPN2_074,2,25469994,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe350Val/c.1048T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),993,54,1056,"0,0511363636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,19",Deleterious,4,Damaging,"17,53",14
"low bq, bad alignment, many samples",UPN2_075,2,25469994,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe350Val/c.1048T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2761,110,2894,"0,0380096752",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,19",Deleterious,4,Damaging,"17,56","14,2"
"low bq, bad alignment, many samples",UPN2_079,2,25469994,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe350Val/c.1048T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1773,98,1883,"0,0520446097",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,19",Deleterious,4,Damaging,"17,31","14,36"
"low bq, bad alignment, many samples",UPN2_085,2,25469994,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe350Val/c.1048T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1238,61,1316,"0,0463525836",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,19",Deleterious,4,Damaging,"17,1","14,36"
"low bq, bad alignment, many samples",UPN2_086,2,25469994,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe350Val/c.1048T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),766,43,812,"0,052955665",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,19",Deleterious,4,Damaging,"17,45","15,6"
"low bq, bad alignment, many samples",UPN2_087,2,25469994,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe350Val/c.1048T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1863,77,1950,"0,0394871795",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,19",Deleterious,4,Damaging,"17,13","14,86"
"low bq, bad alignment, many samples",UPN2_088,2,25469994,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe350Val/c.1048T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1257,48,1318,"0,0364188164",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,19",Deleterious,4,Damaging,"17,69","14,88"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_097,2,25469994,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe350Val/c.1048T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4865,54,4931,"0,0109511255",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,19",Deleterious,4,Damaging,"18,67",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_104,2,25469994,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe350Val/c.1048T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4282,44,4340,"0,0101382488",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,19",Deleterious,4,Damaging,"18,6",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_105,2,25469994,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe350Val/c.1048T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3847,40,3901,"0,0102537811",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,19",Deleterious,4,Damaging,"18,97","15,65"
"low bq, bad alignment, low freq, many artifacts",UPN2_109,2,25469994,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe350Val/c.1048T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),5229,54,5305,"0,0101790763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,19",Deleterious,4,Damaging,"18,8","16,69"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_002,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2398,27,2430,"0,0111111111",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"24,4","14,26"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_089,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3798,84,3890,"0,0215938303",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"24,88","14,38"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),7641,127,7795,"0,0162924952",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"25,25","14,27"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_043,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),5416,71,5513,"0,0128786505",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"25,58","14,46"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_044,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2300,32,2338,"0,0136869119",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"25,32","15,31"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),7479,126,7636,"0,0165007858",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"25,36","15,2"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),6769,83,6888,"0,0120499419",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"25,15","15,61"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),9974,155,10198,"0,0151990586",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"24,98","14,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),7146,87,7251,"0,0119983451",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"25,35","14,82"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),6881,93,7020,"0,0132478632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"25,31","14,59"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),5638,73,5736,"0,0127266388",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"25,73","14,29"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),5796,94,5907,"0,0159133232",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"24,8","14,62"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),6963,106,7106,"0,0149169716",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"24,76","14,19"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4755,62,4841,"0,0128072712",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"25,37","14,11"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_008,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),8320,102,8451,"0,0120695776",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"24,14","14,34"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_009,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),7441,86,7543,"0,0114012992",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"24,64","14,42"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_010,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3967,50,4033,"0,0123977188",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"24,02",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_011,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4541,56,4621,"0,012118589",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"24,65","14,86"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),7446,104,7589,"0,0137040453",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,25,"14,26"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2781,32,2822,"0,0113394755",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"24,99",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_090,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3382,55,3444,"0,0159698026",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"25,22",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),6533,88,6651,"0,0132310931",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"25,08","14,55"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_058,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),5808,78,5910,"0,0131979695",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"25,3","14,26"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_091,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3511,54,3580,"0,0150837989",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"24,8","14,7"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_092,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2078,34,2119,"0,0160453044",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"25,29","14,41"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_093,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2830,50,2883,"0,0173430454",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"24,92","14,26"
"low bq, bad alignment, many samples",UPN2_066,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),752,49,803,"0,0610211706",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"22,3","14,51"
"low bq, bad alignment, many samples",UPN2_086,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),741,68,812,"0,0837438424",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"21,58","14,96"
"low bq, bad alignment, many samples",UPN2_088,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1214,95,1317,"0,0721336371",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"21,94","14,69"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_094,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4253,65,4324,"0,0150323774",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"24,94",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_095,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4114,78,4212,"0,0185185185",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"24,48","14,97"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_096,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3848,84,3939,"0,0213252094",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"24,62","14,15"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_097,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4811,103,4931,"0,020888258",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"24,94","14,53"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_098,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4128,74,4210,"0,0175771971",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"25,08","14,36"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_099,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1960,40,2006,"0,0199401795",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"24,98","14,18"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_100,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3261,52,3321,"0,0156579344",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"24,97","14,56"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_101,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3712,73,3793,"0,0192459794",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"24,94","14,79"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_102,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3916,75,4004,"0,0187312687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"25,21","14,29"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_103,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3435,57,3502,"0,0162764135",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"24,07","14,25"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_104,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4258,71,4340,"0,016359447",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"24,76","14,18"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_105,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3819,66,3901,"0,0169187388",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"24,97","14,85"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_106,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),5013,105,5130,"0,0204678363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"24,85","14,55"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_107,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),6745,130,6893,"0,0188597128",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"24,83","14,16"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_108,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),5358,108,5480,"0,0197080292",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"25,24","14,06"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_109,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),5213,81,5305,"0,0152686145",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"24,61","14,41"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_110,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),5049,89,5150,"0,0172815534",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"24,99","14,08"
"low bq, bad alignment, low freq, many artifacts",UPN2_111,2,25469997,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser349Ala/c.1045T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4605,83,4698,"0,0176670924",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,441,Tolerated,"24,82","14,17"
"low bq, bad alignment, many samples",UPN2_059,2,25470002,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu347Arg/c.1040T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1405,54,1467,"0,036809816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,1,Damaging,"21,04","14,98"
"low bq, bad alignment, many samples",UPN2_060,2,25470002,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu347Arg/c.1040T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2081,65,2153,"0,030190432",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,1,Damaging,"21,2","14,54"
"low bq, bad alignment, many samples",UPN2_061,2,25470002,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu347Arg/c.1040T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2577,90,2679,"0,0335946249",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,1,Damaging,"20,66","14,22"
"low bq, bad alignment, many samples",UPN2_062,2,25470002,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu347Arg/c.1040T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2818,82,2917,"0,028111073",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,1,Damaging,"20,57","14,32"
"low bq, bad alignment, many samples",UPN2_063,2,25470002,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu347Arg/c.1040T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3187,107,3305,"0,0323751891",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,1,Damaging,"21,1","14,13"
"low bq, bad alignment, many samples",UPN2_064,2,25470002,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu347Arg/c.1040T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1925,70,2002,"0,034965035",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,1,Damaging,"21,25","14,39"
"low bq, bad alignment, many samples",UPN2_065,2,25470002,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu347Arg/c.1040T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),985,37,1025,"0,036097561",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,1,Damaging,"21,25","14,89"
"low bq, bad alignment, many samples",UPN2_066,2,25470002,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu347Arg/c.1040T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),771,26,803,"0,0323785803",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,1,Damaging,"21,52","14,5"
"low bq, bad alignment, many samples",UPN2_067,2,25470002,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu347Arg/c.1040T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1185,33,1226,"0,0269168026",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,1,Damaging,"21,48","14,67"
"low bq, bad alignment, many samples",UPN2_068,2,25470002,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu347Arg/c.1040T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1474,51,1530,"0,0333333333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,1,Damaging,"20,46","14,14"
"low bq, bad alignment, many samples",UPN2_069,2,25470002,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu347Arg/c.1040T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3054,104,3181,"0,0326941213",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,1,Damaging,"21,17","14,53"
"low bq, bad alignment, many samples",UPN2_070,2,25470002,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu347Arg/c.1040T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1516,60,1580,"0,0379746835",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,1,Damaging,"20,99",14
"low bq, bad alignment, many samples",UPN2_071,2,25470002,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu347Arg/c.1040T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2492,106,2608,"0,0406441718",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,1,Damaging,"21,06","14,78"
"low bq, bad alignment, many samples",UPN2_072,2,25470002,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu347Arg/c.1040T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3406,101,3531,"0,028603795",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,1,Damaging,"20,78","15,14"
"low bq, bad alignment, many samples",UPN2_073,2,25470002,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu347Arg/c.1040T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2304,59,2379,"0,0248003363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,1,Damaging,"21,28","14,22"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,2,25470002,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu347Arg/c.1040T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1026,21,1056,"0,0198863636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,1,Damaging,"20,87",14
"low bq, bad alignment, many samples",UPN2_075,2,25470002,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu347Arg/c.1040T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2792,90,2894,"0,0310988252",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,1,Damaging,"21,35","14,14"
"low bq, bad alignment, many samples",UPN2_076,2,25470002,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu347Arg/c.1040T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1910,58,1975,"0,0293670886",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,1,Damaging,"20,97","14,24"
"low bq, bad alignment, many samples",UPN2_077,2,25470002,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu347Arg/c.1040T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2124,70,2203,"0,0317748525",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,1,Damaging,"20,57","14,29"
"low bq, bad alignment, many samples",UPN2_078,2,25470002,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu347Arg/c.1040T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2832,122,2972,"0,0410497981",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,1,Damaging,"20,85","14,51"
"low bq, bad alignment, many samples",UPN2_079,2,25470002,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu347Arg/c.1040T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1797,73,1881,"0,0388091441",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,1,Damaging,"20,98","14,4"
"low bq, bad alignment, many samples",UPN2_080,2,25470002,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu347Arg/c.1040T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3240,118,3369,"0,03502523",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,1,Damaging,"20,73","14,11"
"low bq, bad alignment, many samples",UPN2_081,2,25470002,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu347Arg/c.1040T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3716,132,3870,"0,0341085271",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,1,Damaging,"20,72","14,32"
"low bq, bad alignment, many samples",UPN2_082,2,25470002,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu347Arg/c.1040T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1784,54,1842,"0,0293159609",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,1,Damaging,"21,32","14,13"
"low bq, bad alignment, many samples",UPN2_083,2,25470002,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu347Arg/c.1040T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1986,78,2076,"0,0375722543",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,1,Damaging,"20,57","14,59"
"low bq, bad alignment, many samples",UPN2_084,2,25470002,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu347Arg/c.1040T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2688,103,2810,"0,0366548043",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,1,Damaging,"20,5","14,52"
"low bq, bad alignment, many samples",UPN2_085,2,25470002,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu347Arg/c.1040T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1268,41,1316,"0,0311550152",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,1,Damaging,"20,71","14,17"
"low bq, bad alignment, many samples",UPN2_086,2,25470002,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu347Arg/c.1040T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),782,24,812,"0,0295566502",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,1,Damaging,"21,13","14,83"
"low bq, bad alignment, many samples",UPN2_087,2,25470002,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu347Arg/c.1040T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1877,62,1949,"0,0318111852",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,1,Damaging,"20,35",14
"low bq, bad alignment",UPN2_088,2,25470002,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu347Arg/c.1040T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1272,40,1317,"0,0303720577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,1,Damaging,"21,22","14,18"
"low bq, bad alignment, many samples",UPN2_059,2,25470008,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met345Arg/c.1034T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1387,65,1470,"0,0442176871",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,56,Tolerated,"18,1","14,4"
"low bq, bad alignment, many samples",UPN2_060,2,25470008,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met345Arg/c.1034T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2063,86,2160,"0,0398148148",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,56,Tolerated,"17,93","14,51"
"low bq, bad alignment, many samples",UPN2_061,2,25470008,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met345Arg/c.1034T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2538,118,2680,"0,0440298507",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,56,Tolerated,"17,6","14,53"
"low bq, bad alignment, many samples",UPN2_062,2,25470008,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met345Arg/c.1034T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2780,141,2938,"0,0479918312",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,56,Tolerated,"17,44","14,05"
"low bq, bad alignment, many samples",UPN2_063,2,25470008,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met345Arg/c.1034T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3160,120,3312,"0,0362318841",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,56,Tolerated,"17,73","14,38"
"low bq, bad alignment, many samples",UPN2_064,2,25470008,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met345Arg/c.1034T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1941,58,2008,"0,0288844622",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,56,Tolerated,"18,21","14,69"
"low bq, bad alignment, many samples",UPN2_065,2,25470008,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met345Arg/c.1034T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),978,44,1032,"0,0426356589",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,56,Tolerated,"17,88","14,3"
"low bq, bad alignment, many samples",UPN2_066,2,25470008,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met345Arg/c.1034T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),768,25,803,"0,0311332503",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,56,Tolerated,"18,52",14
"low bq, bad alignment, many samples",UPN2_067,2,25470008,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met345Arg/c.1034T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1175,44,1229,"0,0358014646",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,56,Tolerated,"18,24","14,41"
"low bq, bad alignment, many samples",UPN2_068,2,25470008,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met345Arg/c.1034T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1443,71,1533,"0,0463144162",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,56,Tolerated,"17,25","14,18"
"low bq, bad alignment, many samples",UPN2_069,2,25470008,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met345Arg/c.1034T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3010,144,3181,"0,0452687834",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,56,Tolerated,"17,81",14
"low bq, bad alignment, many samples",UPN2_070,2,25470008,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met345Arg/c.1034T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1499,74,1584,"0,0467171717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,56,Tolerated,"17,69","14,09"
"low bq, bad alignment, many samples",UPN2_071,2,25470008,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met345Arg/c.1034T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2504,86,2615,"0,0328871893",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,56,Tolerated,"18,15","14,5"
"low bq, bad alignment, many samples",UPN2_072,2,25470008,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met345Arg/c.1034T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3352,153,3535,"0,043281471",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,56,Tolerated,"17,66","14,29"
"low bq, bad alignment, many samples",UPN2_073,2,25470008,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met345Arg/c.1034T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2259,95,2379,"0,0399327449",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,56,Tolerated,"18,03","14,14"
"low bq, bad alignment, many samples",UPN2_074,2,25470008,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met345Arg/c.1034T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1008,41,1057,"0,0387890255",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,56,Tolerated,18,14
"low bq, bad alignment, many samples",UPN2_075,2,25470008,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met345Arg/c.1034T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2779,96,2897,"0,0331377287",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,56,Tolerated,"18,27",14
"low bq, bad alignment, many samples",UPN2_076,2,25470008,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met345Arg/c.1034T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1888,78,1979,"0,0394138454",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,56,Tolerated,"17,61","14,17"
"low bq, bad alignment, many samples",UPN2_077,2,25470008,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met345Arg/c.1034T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2076,110,2210,"0,0497737557",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,56,Tolerated,"17,89","14,18"
"low bq, bad alignment, many samples",UPN2_078,2,25470008,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met345Arg/c.1034T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2814,131,2970,"0,0441077441",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,56,Tolerated,"17,57","14,31"
"low bq, bad alignment, many samples",UPN2_079,2,25470008,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met345Arg/c.1034T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1773,93,1883,"0,0493892724",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,56,Tolerated,"17,77","14,14"
"low bq, bad alignment, many samples",UPN2_080,2,25470008,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met345Arg/c.1034T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3209,141,3380,"0,0417159763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,56,Tolerated,"17,86","14,24"
"low bq, bad alignment, many samples",UPN2_081,2,25470008,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met345Arg/c.1034T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3696,137,3871,"0,0353913717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,56,Tolerated,"17,87","14,19"
"low bq, bad alignment, many samples",UPN2_082,2,25470008,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met345Arg/c.1034T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1768,64,1846,"0,0346695558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,56,Tolerated,"18,14",14
"low bq, bad alignment, many samples",UPN2_083,2,25470008,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met345Arg/c.1034T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1983,88,2082,"0,0422670509",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,56,Tolerated,"17,53",14
"low bq, bad alignment, many samples",UPN2_084,2,25470008,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met345Arg/c.1034T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2640,145,2816,"0,0514914773",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,56,Tolerated,"18,09","14,05"
"low bq, bad alignment, many samples",UPN2_085,2,25470008,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met345Arg/c.1034T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1244,59,1317,"0,0447987851",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,56,Tolerated,"17,98","14,22"
"low bq, bad alignment, many samples",UPN2_086,2,25470008,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met345Arg/c.1034T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),776,32,813,"0,0393603936",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,56,Tolerated,"17,87","14,22"
"low bq, bad alignment, many samples",UPN2_087,2,25470008,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met345Arg/c.1034T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1851,83,1951,"0,042542286",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,56,Tolerated,"17,75",14
"low bq, bad alignment",UPN2_088,2,25470008,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met345Arg/c.1034T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1261,45,1319,"0,0341167551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,56,Tolerated,"18,26","14,29"
"inspected, many artifacts",UPN2_048,2,25470008,A,G,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met345Thr/c.1034T>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),2507,36,2564,"0,0140405616",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,34",Neutral,"0,15",Tolerated,"21,66","32,56"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,25470009,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met345Leu/c.1033A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),2419,31,2464,"0,0125811688",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,1,Tolerated,"29,51","26,06"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,2,25470009,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met345Leu/c.1033A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),2732,39,2786,"0,0139985642",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,1,Tolerated,"26,51","14,51"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,2,25470009,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met345Leu/c.1033A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),2954,38,3012,"0,0126162019",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,1,Tolerated,"26,77","14,71"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,2,25470009,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met345Leu/c.1033A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),3342,43,3399,"0,0126507796",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,1,Tolerated,"26,59","14,16"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,2,25470009,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met345Leu/c.1033A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),2034,27,2074,"0,0130183221",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,1,Tolerated,"26,88","14,48"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_069,2,25470009,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met345Leu/c.1033A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),3199,35,3251,"0,0107659182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,1,Tolerated,"26,76","14,94"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,2,25470009,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met345Leu/c.1033A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),2629,30,2670,"0,0112359551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,1,Tolerated,"26,72","14,73"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,2,25470009,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met345Leu/c.1033A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),3561,43,3614,"0,0118981738",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,1,Tolerated,"26,7","14,3"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,2,25470009,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met345Leu/c.1033A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),2413,27,2455,"0,0109979633",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,1,Tolerated,"26,77","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25470009,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met345Leu/c.1033A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),2915,30,2958,"0,0101419878",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,1,Tolerated,"27,09",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,2,25470009,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met345Leu/c.1033A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),1982,24,2014,"0,0119165839",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,1,Tolerated,"26,35","14,75"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,2,25470009,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met345Leu/c.1033A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),2222,31,2265,"0,0136865342",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,1,Tolerated,"26,44",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,2,25470009,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met345Leu/c.1033A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),3011,38,3064,"0,0124020888",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,1,Tolerated,"26,4",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_079,2,25470009,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met345Leu/c.1033A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),1904,23,1934,"0,0118924509",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,1,Tolerated,"26,68","14,3"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,2,25470009,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met345Leu/c.1033A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),3443,37,3491,"0,0105986823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,1,Tolerated,"26,48","15,19"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_081,2,25470009,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met345Leu/c.1033A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),3938,40,3992,"0,0100200401",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,1,Tolerated,"26,84","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25470009,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met345Leu/c.1033A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),1861,21,1894,"0,0110876452",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,1,Tolerated,"27,01","15,05"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,2,25470009,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met345Leu/c.1033A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),2111,31,2150,"0,0144186047",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,1,Tolerated,"26,24","14,58"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,2,25470009,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met345Leu/c.1033A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),2837,35,2883,"0,0121401318",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,1,Tolerated,"26,48","14,37"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_085,2,25470009,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met345Leu/c.1033A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),1331,21,1354,"0,0155096012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,1,Tolerated,"26,3","16,1"
"low bq, low freq, many artifacts",UPN2_088,2,25470009,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met345Leu/c.1033A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),1322,24,1352,"0,0177514793",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,1,Tolerated,"27,06","15,08"
"low bq, bad alignment, many samples",UPN2_059,2,25470011,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu344Arg/c.1031T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2782,77,2867,"0,0268573422",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,0,Damaging,24,14
"low bq, bad alignment, many samples",UPN2_060,2,25470011,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu344Arg/c.1031T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4095,122,4248,"0,0287193974",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,0,Damaging,"23,94","15,01"
"low bq, bad alignment, many samples",UPN2_061,2,25470011,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu344Arg/c.1031T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),5036,158,5217,"0,0302856048",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,0,Damaging,"23,66","14,29"
"low bq, bad alignment, many samples",UPN2_062,2,25470011,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu344Arg/c.1031T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),5556,165,5747,"0,0287106316",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,0,Damaging,"23,34","14,64"
"low bq, bad alignment, many samples",UPN2_063,2,25470011,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu344Arg/c.1031T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),6253,182,6476,"0,0281037678",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,0,Damaging,"23,88",14
"low bq, bad alignment, many samples",UPN2_064,2,25470011,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu344Arg/c.1031T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3789,94,3914,"0,0240163516",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,0,Damaging,"23,95","14,21"
"low bq, bad alignment, many samples",UPN2_065,2,25470011,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu344Arg/c.1031T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1938,58,2019,"0,0287270926",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,0,Damaging,"24,09","14,12"
"low bq, bad alignment, many samples",UPN2_066,2,25470011,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu344Arg/c.1031T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1532,36,1570,"0,0229299363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,0,Damaging,"24,01","14,19"
"low bq, bad alignment, many samples",UPN2_067,2,25470011,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu344Arg/c.1031T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2346,81,2437,"0,0332375872",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,0,Damaging,"24,21","14,09"
"low bq, bad alignment, many samples",UPN2_068,2,25470011,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu344Arg/c.1031T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2932,106,3054,"0,0347085789",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,0,Damaging,"23,41","14,48"
"low bq, bad alignment, many samples",UPN2_069,2,25470011,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu344Arg/c.1031T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),6052,171,6253,"0,0273468735",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,0,Damaging,"23,97","14,19"
"low bq, bad alignment, many samples",UPN2_070,2,25470011,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu344Arg/c.1031T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3029,98,3140,"0,0312101911",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,0,Damaging,"23,59","14,07"
"low bq, bad alignment, many samples",UPN2_071,2,25470011,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu344Arg/c.1031T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4959,131,5119,"0,0255909357",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,0,Damaging,"23,81","15,02"
"low bq, bad alignment, many samples",UPN2_072,2,25470011,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu344Arg/c.1031T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),6750,192,6963,"0,0275743214",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,0,Damaging,"23,79","14,38"
"low bq, bad alignment, many samples",UPN2_073,2,25470011,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu344Arg/c.1031T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4536,123,4697,"0,0261869278",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,0,Damaging,"24,17","14,11"
"low bq, bad alignment, many samples",UPN2_074,2,25470011,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu344Arg/c.1031T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2005,57,2070,"0,0275362319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,0,Damaging,"23,99","14,25"
"low bq, bad alignment, many samples",UPN2_075,2,25470011,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu344Arg/c.1031T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),5564,139,5728,"0,0242667598",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,0,Damaging,"23,86","14,19"
"low bq, bad alignment, many samples",UPN2_076,2,25470011,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu344Arg/c.1031T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3722,121,3862,"0,0313309166",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,0,Damaging,"23,4","14,69"
"low bq, bad alignment, many samples",UPN2_077,2,25470011,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu344Arg/c.1031T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4191,109,4325,"0,0252023121",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,0,Damaging,"23,65","14,5"
"low bq, bad alignment, many samples",UPN2_078,2,25470011,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu344Arg/c.1031T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),5664,156,5844,"0,0266940452",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,0,Damaging,"23,63","14,13"
"low bq, bad alignment, many samples",UPN2_079,2,25470011,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu344Arg/c.1031T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3609,89,3722,"0,0239118753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,0,Damaging,"23,65",14
"low bq, bad alignment, many samples",UPN2_080,2,25470011,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu344Arg/c.1031T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),6401,178,6611,"0,0269248223",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,0,Damaging,"23,66","14,57"
"low bq, bad alignment, many samples",UPN2_081,2,25470011,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu344Arg/c.1031T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),7473,196,7698,"0,0254611587",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,0,Damaging,"23,72","14,2"
"low bq, bad alignment, many samples",UPN2_082,2,25470011,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu344Arg/c.1031T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3527,97,3638,"0,0266630016",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,0,Damaging,"24,25","14,07"
"low bq, bad alignment, many samples",UPN2_083,2,25470011,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu344Arg/c.1031T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3932,145,4094,"0,0354176844",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,0,Damaging,"23,32",14
"low bq, bad alignment, many samples",UPN2_084,2,25470011,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu344Arg/c.1031T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),5384,177,5591,"0,0316580218",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,0,Damaging,"23,75","14,18"
"low bq, bad alignment, many samples",UPN2_085,2,25470011,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu344Arg/c.1031T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2507,64,2602,"0,0245964643",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,0,Damaging,"23,58",14
"low bq, bad alignment, many samples",UPN2_086,2,25470011,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu344Arg/c.1031T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1552,43,1601,"0,0268582136",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,0,Damaging,"23,52","14,42"
"low bq, bad alignment, many samples",UPN2_087,2,25470011,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu344Arg/c.1031T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3713,115,3864,"0,0297619048",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,0,Damaging,"23,61","14,73"
"low bq, bad alignment",UPN2_088,2,25470011,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu344Arg/c.1031T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2480,59,2559,"0,0230558812",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,0,Damaging,"23,83",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_059,2,25470014,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys343Thr/c.1028A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),2818,36,2868,"0,0125523013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,36,Damaging,"24,79",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_060,2,25470014,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys343Thr/c.1028A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),4195,43,4254,"0,0101081335",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,36,Damaging,"25,24","15,02"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,2,25470014,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys343Thr/c.1028A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),5136,59,5222,"0,0112983531",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,36,Damaging,"24,3","14,22"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,2,25470014,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys343Thr/c.1028A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),5625,81,5747,"0,0140943101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,36,Damaging,"24,2","14,91"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,2,25470014,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys343Thr/c.1028A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),6379,78,6478,"0,0120407533",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,36,Damaging,"25,01","14,26"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,2,25470014,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys343Thr/c.1028A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),3857,55,3923,"0,0140198827",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,36,Damaging,"25,32","14,98"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_065,2,25470014,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys343Thr/c.1028A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),1976,37,2023,"0,0182896688",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,36,Damaging,"25,41","15,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_066,2,25470014,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys343Thr/c.1028A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),1538,24,1574,"0,0152477764",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,36,Damaging,"25,45",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_067,2,25470014,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys343Thr/c.1028A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),2380,41,2438,"0,0168170632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,36,Damaging,"25,28",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_068,2,25470014,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys343Thr/c.1028A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),2994,41,3055,"0,0134206219",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,36,Damaging,"24,53","14,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_069,2,25470014,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys343Thr/c.1028A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),6137,91,6259,"0,0145390637",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,36,Damaging,"25,09","14,3"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_070,2,25470014,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys343Thr/c.1028A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),3064,64,3141,"0,0203756765",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,36,Damaging,"24,82","14,72"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,2,25470014,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys343Thr/c.1028A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),5037,65,5125,"0,0126829268",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,36,Damaging,"25,28","15,18"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,2,25470014,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys343Thr/c.1028A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),6851,98,6974,"0,0140521939",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,36,Damaging,"24,99","14,4"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,2,25470014,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys343Thr/c.1028A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),4615,67,4706,"0,0142371441",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,36,Damaging,"25,08","14,57"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,2,25470014,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys343Thr/c.1028A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),2042,24,2073,"0,011577424",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,36,Damaging,"25,29",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_075,2,25470014,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys343Thr/c.1028A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),5628,84,5736,"0,0146443515",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,36,Damaging,"25,13","14,77"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,2,25470014,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys343Thr/c.1028A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),3791,49,3862,"0,0126877266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,36,Damaging,"24,56",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,2,25470014,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys343Thr/c.1028A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),4252,59,4325,"0,0136416185",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,36,Damaging,"24,49","14,22"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,2,25470014,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys343Thr/c.1028A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),5726,92,5855,"0,0157130658",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,36,Damaging,"24,47","14,36"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_079,2,25470014,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys343Thr/c.1028A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),3652,50,3722,"0,0134336378",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,36,Damaging,"24,91","14,8"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,2,25470014,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys343Thr/c.1028A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),6479,113,6618,"0,0170746449",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,36,Damaging,"24,63","14,56"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_081,2,25470014,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys343Thr/c.1028A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),7578,97,7706,"0,0125875941",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,36,Damaging,"25,06","14,27"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_082,2,25470014,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys343Thr/c.1028A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),3574,50,3641,"0,0137324911",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,36,Damaging,"25,29","15,36"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,2,25470014,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys343Thr/c.1028A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),4011,55,4097,"0,0134244569",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,36,Damaging,"24,31","14,36"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,2,25470014,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys343Thr/c.1028A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),5493,89,5596,"0,0159042173",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,36,Damaging,"24,67","14,92"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_085,2,25470014,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys343Thr/c.1028A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),2559,37,2606,"0,0141980046",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,36,Damaging,"24,89","14,35"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,2,25470014,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys343Thr/c.1028A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),1566,22,1602,"0,013732834",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,36,Damaging,"24,88","14,59"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_087,2,25470014,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys343Thr/c.1028A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),3793,50,3865,"0,0129366106",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,36,Damaging,25,"14,26"
"low bq, bad alignment, low freq, many artifacts",UPN2_088,2,25470014,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys343Thr/c.1028A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),2517,33,2565,"0,0128654971",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,36,Damaging,"24,98","15,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_059,2,25470015,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys343Gln/c.1027A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),2817,37,2866,"0,0129099791",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,161,Tolerated,"26,21",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_060,2,25470015,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys343Gln/c.1027A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),4175,48,4253,"0,011286151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,161,Tolerated,"26,3",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,2,25470015,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys343Gln/c.1027A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),5120,72,5224,"0,0137825421",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,161,Tolerated,"25,89",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,2,25470015,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys343Gln/c.1027A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),5642,77,5746,"0,0134006265",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,161,Tolerated,"25,7",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,2,25470015,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys343Gln/c.1027A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),6328,107,6474,"0,0165276491",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,161,Tolerated,"26,34","14,6"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,2,25470015,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys343Gln/c.1027A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),3863,47,3923,"0,0119806271",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,161,Tolerated,"26,19","14,43"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_065,2,25470015,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys343Gln/c.1027A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),1995,22,2023,"0,0108749382",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,161,Tolerated,"26,33","14,91"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_066,2,25470015,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys343Gln/c.1027A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),1540,25,1574,"0,0158831004",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,161,Tolerated,"26,61","15,68"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_067,2,25470015,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys343Gln/c.1027A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),2400,32,2438,"0,0131255127",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,161,Tolerated,"26,25","14,22"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_069,2,25470015,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys343Gln/c.1027A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),6137,90,6260,"0,0143769968",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,161,Tolerated,"26,21","14,44"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_070,2,25470015,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys343Gln/c.1027A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),3073,47,3142,"0,0149586251",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,161,Tolerated,"26,12","14,43"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,2,25470015,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys343Gln/c.1027A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),5020,77,5128,"0,0150156006",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,161,Tolerated,"26,13","14,52"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,2,25470015,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys343Gln/c.1027A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),6851,92,6975,"0,0131899642",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,161,Tolerated,"26,09","14,63"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,2,25470015,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys343Gln/c.1027A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),4611,75,4708,"0,0159303314",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,161,Tolerated,"26,45","14,77"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,2,25470015,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys343Gln/c.1027A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),2033,32,2073,"0,0154365654",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,161,Tolerated,"26,42",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_075,2,25470015,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys343Gln/c.1027A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),5645,78,5740,"0,0135888502",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,161,Tolerated,"26,57","14,33"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,2,25470015,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys343Gln/c.1027A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),3793,55,3863,"0,0142376391",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,161,Tolerated,"25,95","14,8"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,2,25470015,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys343Gln/c.1027A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),4238,60,4321,"0,0138856746",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,161,Tolerated,"25,8","14,33"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,2,25470015,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys343Gln/c.1027A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),5720,90,5851,"0,015381986",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,161,Tolerated,"25,88","14,87"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_079,2,25470015,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys343Gln/c.1027A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),3646,63,3723,"0,0169218372",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,161,Tolerated,"25,95","14,6"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,2,25470015,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys343Gln/c.1027A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),6482,90,6618,"0,0135992747",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,161,Tolerated,"26,09","15,11"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_081,2,25470015,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys343Gln/c.1027A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),7581,97,7707,"0,0125859608",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,161,Tolerated,"26,37","14,47"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_082,2,25470015,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys343Gln/c.1027A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),3573,49,3643,"0,0134504529",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,161,Tolerated,"26,49","14,73"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,2,25470015,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys343Gln/c.1027A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),4029,53,4096,"0,0129394531",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,161,Tolerated,"25,64","14,47"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,2,25470015,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys343Gln/c.1027A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),5499,71,5597,"0,0126853672",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,161,Tolerated,"25,94",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_085,2,25470015,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys343Gln/c.1027A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),2567,34,2604,"0,0130568356",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,161,Tolerated,"26,11","14,91"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,2,25470015,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys343Gln/c.1027A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),1567,30,1602,"0,0187265918",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,161,Tolerated,"26,02",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_087,2,25470015,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys343Gln/c.1027A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),3817,41,3866,"0,0106052768",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,161,Tolerated,"26,31","14,8"
"low bq, bad alignment, low freq, many artifacts",UPN2_088,2,25470015,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys343Gln/c.1027A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|G),2527,36,2567,"0,0140241527",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,161,Tolerated,"26,35",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_089,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),7582,130,7750,"0,0167741935",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"22,25","14,1"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),15052,174,15436,"0,0112723503",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"21,89","14,35"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_043,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),10687,118,10937,"0,0107890646",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"22,05","14,97"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_044,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4514,64,4631,"0,0138199093",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"21,85","14,69"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),14723,214,15137,"0,0141375438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"21,81","14,17"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),13293,154,13662,"0,0112721417",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"21,85","14,55"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),19684,264,20206,"0,0130654261",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"21,94","15,09"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_048,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4980,53,5111,"0,0103697906",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"22,11",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_006,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2805,35,2891,"0,0121065375",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"21,48",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),14038,175,14395,"0,012156999",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"21,71","14,98"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),11105,125,11391,"0,0109735756",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"22,2","14,89"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),11415,151,11709,"0,0128960629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"21,71","14,62"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),13708,163,14079,"0,0115775268",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"21,58","14,36"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),9337,106,9558,"0,0110901862",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"21,73","14,27"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),14646,191,15048,"0,0126927166",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"21,79","14,51"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),5490,66,5605,"0,0117752007",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"21,85",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_090,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),6767,106,6899,"0,0153645456",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"22,33","14,48"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),12863,143,13179,"0,0108505956",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"21,87","14,24"
"low bq, bad alignment, many samples",UPN2_059,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2660,162,2858,"0,0566829951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"20,47","14,24"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_091,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),6957,122,7124,"0,0171252106",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"22,19","14,62"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_092,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4149,61,4236,"0,0144003777",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"21,94","14,8"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_093,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),5618,92,5741,"0,0160250827",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"22,12","14,55"
"low bq, bad alignment, many samples",UPN2_061,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4828,304,5207,"0,058382946",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"19,97","14,41"
"low bq, bad alignment, many samples",UPN2_062,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),5319,352,5731,"0,0614203455",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"19,98","14,4"
"low bq, bad alignment, many samples",UPN2_063,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),5985,391,6453,"0,0605919727",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"20,31","14,15"
"low bq, bad alignment, many samples",UPN2_064,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3627,221,3911,"0,0565072871",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"20,47","14,21"
"low bq, bad alignment, many samples",UPN2_065,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1879,115,2016,"0,0570436508",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"20,25","14,17"
"low bq, bad alignment, many samples",UPN2_066,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1472,80,1568,"0,0510204082",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"20,62",14
"low bq, bad alignment, many samples",UPN2_067,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2266,137,2436,"0,0562397373",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"20,46","14,32"
"low bq, bad alignment, many samples",UPN2_068,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2833,166,3044,"0,0545335085",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"20,27","14,04"
"low bq, bad alignment, many samples",UPN2_069,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),5806,388,6246,"0,0621197566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"20,5","14,18"
"low bq, bad alignment, many samples",UPN2_070,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2913,193,3134,"0,061582642",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"20,34","14,27"
"low bq, bad alignment, many samples",UPN2_071,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4766,285,5115,"0,0557184751",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"20,36","14,43"
"low bq, bad alignment, many samples",UPN2_072,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),6494,384,6952,"0,0552359033",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"20,29","14,17"
"low bq, bad alignment, many samples",UPN2_073,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4355,283,4695,"0,0602768903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"20,51","14,18"
"low bq, bad alignment, many samples",UPN2_074,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1924,112,2064,"0,0542635659",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"20,54","14,23"
"low bq, bad alignment, many samples",UPN2_075,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),5371,304,5729,"0,0530633618",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"20,17","14,15"
"low bq, bad alignment, many samples",UPN2_076,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3558,234,3842,"0,0609057782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"20,37","14,35"
"low bq, bad alignment, many samples",UPN2_077,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4016,248,4308,"0,0575673166",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"20,17","14,23"
"low bq, bad alignment, many samples",UPN2_078,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),5402,353,5824,"0,0606112637",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"20,29","14,15"
"low bq, bad alignment, many samples",UPN2_079,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3464,212,3718,"0,0570199032",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"20,3","14,22"
"low bq, bad alignment, many samples",UPN2_080,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),6086,426,6595,"0,0645943897",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"20,09","14,22"
"low bq, bad alignment, many samples",UPN2_081,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),7162,450,7686,"0,0585480094",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"20,43","14,26"
"low bq, bad alignment, many samples",UPN2_082,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3388,208,3636,"0,0572057206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"20,63","14,28"
"low bq, bad alignment, many samples",UPN2_084,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),5187,319,5568,"0,0572916667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"20,22","14,29"
"low bq, bad alignment, many samples",UPN2_085,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2406,154,2594,"0,0593677718",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"20,57","14,08"
"low bq, bad alignment, many samples",UPN2_086,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1501,77,1597,"0,0482154039",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"20,07",14
"low bq, bad alignment, many samples",UPN2_087,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3575,232,3856,"0,0601659751",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"20,41","14,22"
"low bq, bad alignment, many samples",UPN2_088,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2404,130,2557,"0,0508408291",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"19,92","14,25"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_094,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),8423,148,8629,"0,017151466",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"22,13","14,43"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_095,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),8224,141,8426,"0,0167339188",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"21,89","14,1"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_096,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),7693,114,7866,"0,0144927536",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"22,1",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_097,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),9610,172,9828,"0,0175010175",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"22,15","14,19"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_098,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),8203,126,8396,"0,0150071463",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"22,04","14,5"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_099,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3893,70,3995,"0,0175219024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"22,07",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_100,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),6494,100,6626,"0,0150920616",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"22,15",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_101,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),7405,121,7586,"0,015950435",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"22,09","14,12"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_102,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),7778,135,7981,"0,0169151735",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"22,07","14,23"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_103,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),6837,96,6969,"0,0137752906",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"21,66","14,14"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_104,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),8437,149,8647,"0,0172314097",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"22,06","14,05"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_105,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),7598,131,7780,"0,0168380463",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"22,04","14,33"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_106,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),9959,168,10186,"0,016493226",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"22,08","14,3"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_107,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),13383,233,13700,"0,0170072993",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"21,99","14,26"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_108,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),10691,174,10927,"0,0159238583",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"22,21","14,3"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_109,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),10375,164,10595,"0,0154789995",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"22,16","14,04"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_110,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),10056,164,10292,"0,0159347066",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"22,12","14,08"
"low bq, bad alignment, low freq, many artifacts",UPN2_111,2,25470020,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val341Gly/c.1022T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),9144,163,9371,"0,0173940881",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,37,Damaging,"22,05","14,22"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_089,2,25470022,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys340Trp/c.1020T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),7540,162,7748,"0,0209086216",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,44,Damaging,"23,52","14,86"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,2,25470022,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys340Trp/c.1020T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),15092,182,15438,"0,0117890919",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,44,Damaging,"23,7","14,8"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_043,2,25470022,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys340Trp/c.1020T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),10722,115,10940,"0,010511883",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,44,Damaging,"23,91","14,67"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_044,2,25470022,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys340Trp/c.1020T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4514,61,4631,"0,0131721011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,44,Damaging,"23,73","15,3"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,2,25470022,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys340Trp/c.1020T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),14806,161,15137,"0,0106361895",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,44,Damaging,"23,74","14,42"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,2,25470022,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys340Trp/c.1020T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),13356,157,13664,"0,0114900468",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,44,Damaging,"23,56","14,08"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,2,25470022,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys340Trp/c.1020T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),19785,214,20209,"0,0105893414",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,44,Damaging,"23,55","14,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_048,2,25470022,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys340Trp/c.1020T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4945,66,5116,"0,0129007037",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,44,Damaging,"23,67","14,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,2,25470022,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys340Trp/c.1020T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),14081,146,14394,"0,0101431152",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,44,Damaging,"23,52",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,2,25470022,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys340Trp/c.1020T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),13669,143,13953,"0,010248692",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,44,Damaging,"23,46","14,55"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,2,25470022,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys340Trp/c.1020T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),11152,120,11392,"0,0105337079",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,44,Damaging,"23,92","14,44"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,2,25470022,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys340Trp/c.1020T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),11412,161,11710,"0,0137489325",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,44,Damaging,"23,48","15,2"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,2,25470022,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys340Trp/c.1020T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),13773,183,14081,"0,0129962361",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,44,Damaging,"23,25","15,03"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,2,25470022,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys340Trp/c.1020T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),9329,110,9559,"0,0115074799",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,44,Damaging,"23,39","15,06"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,2,25470022,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys340Trp/c.1020T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),14721,172,15049,"0,0114293309",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,44,Damaging,"23,43","14,12"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,2,25470022,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys340Trp/c.1020T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),5497,60,5607,"0,0107009096",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,44,Damaging,"23,44","14,82"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_090,2,25470022,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys340Trp/c.1020T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),6759,109,6900,"0,0157971014",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,44,Damaging,"23,65","14,47"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,2,25470022,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys340Trp/c.1020T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),12863,138,13184,"0,010467233",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,44,Damaging,"23,67","14,29"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_058,2,25470022,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys340Trp/c.1020T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),11450,149,11705,"0,0127296027",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,44,Damaging,"23,8","14,17"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_091,2,25470022,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys340Trp/c.1020T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),6950,140,7124,"0,019651881",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,44,Damaging,"23,36","14,5"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_092,2,25470022,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys340Trp/c.1020T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4136,69,4235,"0,0162927981",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,44,Damaging,"23,3","14,58"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_093,2,25470022,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys340Trp/c.1020T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),5611,91,5741,"0,0158508971",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,44,Damaging,"23,46","14,48"
"low bq, bad alignment, many samples",UPN2_079,2,25470022,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys340Trp/c.1020T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3473,207,3716,"0,0557050592",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,44,Damaging,"21,43","14,26"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_094,2,25470022,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys340Trp/c.1020T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),8425,163,8629,"0,0188897902",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,44,Damaging,"23,34","14,25"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_095,2,25470022,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys340Trp/c.1020T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),8207,165,8428,"0,0195775985",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,44,Damaging,"23,13","14,04"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_096,2,25470022,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys340Trp/c.1020T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),7701,138,7867,"0,0175416296",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,44,Damaging,"23,34","14,64"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_097,2,25470022,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys340Trp/c.1020T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),9607,181,9830,"0,0184130214",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,44,Damaging,"23,37","14,19"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_098,2,25470022,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys340Trp/c.1020T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),8205,143,8397,"0,0170298916",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,44,Damaging,"23,36","14,37"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_099,2,25470022,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys340Trp/c.1020T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3902,67,3995,"0,0167709637",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,44,Damaging,"23,32","14,46"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_100,2,25470022,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys340Trp/c.1020T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),6495,102,6625,"0,0153962264",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,44,Damaging,"23,33","14,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_101,2,25470022,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys340Trp/c.1020T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),7387,135,7584,"0,0178006329",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,44,Damaging,"23,47","14,1"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_102,2,25470022,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys340Trp/c.1020T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),7776,166,7980,"0,020802005",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,44,Damaging,"23,37","14,27"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_103,2,25470022,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys340Trp/c.1020T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),6811,114,6969,"0,0163581576",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,44,Damaging,"22,91","14,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_104,2,25470022,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys340Trp/c.1020T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),8445,166,8647,"0,0191974095",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,44,Damaging,"23,16","14,27"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_105,2,25470022,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys340Trp/c.1020T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),7605,145,7780,"0,0186375321",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,44,Damaging,"23,47","14,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_106,2,25470022,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys340Trp/c.1020T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),9964,176,10184,"0,017282011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,44,Damaging,"23,3","14,19"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_107,2,25470022,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys340Trp/c.1020T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),13397,238,13698,"0,0173747992",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,44,Damaging,"23,25","14,19"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_108,2,25470022,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys340Trp/c.1020T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),10687,180,10927,"0,0164729569",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,44,Damaging,"23,51","14,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_109,2,25470022,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys340Trp/c.1020T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),10352,200,10594,"0,0188786105",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,44,Damaging,"23,28","14,23"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_110,2,25470022,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys340Trp/c.1020T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),10049,186,10292,"0,0180722892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,44,Damaging,"23,55","14,31"
"low bq, bad alignment, low freq, many artifacts",UPN2_111,2,25470022,A,C,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys340Trp/c.1020T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),9140,178,9370,"0,0189967983",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,44,Damaging,"23,18","14,4"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_001,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3469,59,3551,"0,016615038",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"23,04","14,97"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_015,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),12396,179,12716,"0,0140767537",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,44","14,16"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_017,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4057,53,4142,"0,0127957508",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,52",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_018,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),6949,95,7098,"0,0133840518",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,86","14,44"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_019,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),7016,94,7168,"0,0131138393",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,47",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_020,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),5939,63,6043,"0,0104252855",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,62","14,81"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_021,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),7520,94,7663,"0,0122667363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,83","14,07"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_002,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4694,86,4831,"0,0178016974",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,64",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_022,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),8246,127,8437,"0,0150527439",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,62","14,31"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_023,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),9541,116,9755,"0,0118913378",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,73",14
"low bq, bad alignment, many samples",UPN2_041,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1215,36,1260,"0,0285714286",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"23,3",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_024,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4404,64,4514,"0,0141781125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,81","15,38"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_025,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),11777,138,12008,"0,0114923384",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,87","14,05"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_026,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),11269,173,11518,"0,0150199687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,34","14,12"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_004,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1058,24,1102,"0,0217785844",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,49",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_027,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),10835,148,11079,"0,0133586064",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,51","14,21"
"low bq, bad alignment, many samples",UPN2_089,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),7371,321,7750,"0,0414193548",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,97","14,11"
"low bq, bad alignment, many samples",UPN2_042,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),14898,359,15441,"0,0232497895",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,86","14,31"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_028,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),8117,146,8327,"0,0175333253",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,47","14,84"
"low bq, bad alignment, many samples",UPN2_043,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),10509,276,10943,"0,0252216029",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"23,2","14,66"
"low bq, bad alignment, many samples",UPN2_044,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4475,114,4635,"0,0245954693",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,99","14,29"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_029,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),10390,141,10631,"0,0132630985",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,8",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_030,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),9295,121,9479,"0,0127650596",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,74","14,58"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_031,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),6804,76,6942,"0,0109478536",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,73",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_005,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1555,27,1589,"0,0169918188",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,88","14,67"
"low bq, bad alignment, many samples",UPN2_045,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),14573,385,15139,"0,025431006",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"23,06","14,73"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_032,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3589,43,3671,"0,0117134296",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,8","14,47"
"low bq, bad alignment, many samples",UPN2_046,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),13149,359,13670,"0,0262618873",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,85","14,25"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_033,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),7514,79,7640,"0,0103403141",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,87","14,44"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_034,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2691,44,2765,"0,0159132007",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,2",14
"low bq, bad alignment, many samples",UPN2_047,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),19472,535,20215,"0,0264654959",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,89","14,13"
"low bq, bad alignment, many samples",UPN2_048,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4935,128,5119,"0,0250048838",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"23,04","14,43"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_035,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),9302,117,9469,"0,0123561094",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,8","14,15"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_036,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),14214,198,14527,"0,0136297928",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,74","14,2"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_006,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2811,53,2892,"0,0183264177",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,85",14
"low bq, bad alignment, many samples",UPN2_049,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),13899,343,14397,"0,0238244079",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,91","14,11"
"low bq, bad alignment, many samples",UPN2_050,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),13478,330,13956,"0,0236457438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,83","14,95"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_037,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),17124,270,17528,"0,0154039251",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,48","14,4"
"low bq, bad alignment, many samples",UPN2_051,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),10997,255,11393,"0,0223821645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"23,1","14,44"
"low bq, bad alignment, many samples",UPN2_052,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),11255,301,11711,"0,0257023311",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,7","14,49"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_038,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),17278,231,17658,"0,0130818892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,59","14,42"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_039,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),15002,206,15332,"0,013435951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,38","14,17"
"low bq, bad alignment, many samples",UPN2_053,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),13579,348,14083,"0,024710644",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,59","14,32"
"low bq, bad alignment, many samples",UPN2_054,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),9200,256,9564,"0,0267670431",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,76","14,22"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_007,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),11673,179,11951,"0,0149778261",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"23,25",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_008,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),16423,319,16884,"0,0188936271",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,88","14,35"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_009,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),14665,261,15048,"0,0173444976",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,93","14,52"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_010,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),7797,166,8057,"0,0206032022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,81","14,69"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_011,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),8992,137,9198,"0,0148945423",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"23,12",14
"low bq, bad alignment, many samples",UPN2_055,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),14512,357,15055,"0,0237130521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,75","14,4"
"low bq, bad alignment, many samples",UPN2_056,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),5401,144,5608,"0,0256776034",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,93","14,05"
"low bq, bad alignment, many samples",UPN2_090,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),6600,257,6901,"0,0372409796",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,94","14,1"
"low bq, bad alignment, many samples",UPN2_057,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),12670,354,13187,"0,0268446197",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,23,"14,43"
"low bq, bad alignment, many samples",UPN2_058,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),11280,290,11708,"0,0247693885",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"23,12","14,31"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_012,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),5901,106,6064,"0,0174802111",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"23,15",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_040,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),5600,73,5720,"0,0127622378",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,67",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_013,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3046,48,3114,"0,0154142582",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,82",14
"low bq, bad alignment, many samples",UPN2_091,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),6827,281,7125,"0,0394385965",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,88","14,21"
"low bq, bad alignment, many samples",UPN2_092,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4053,148,4235,"0,0349468713",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,95","14,27"
"low bq, bad alignment, many samples",UPN2_093,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),5488,234,5742,"0,0407523511",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,83","14,09"
"low bq, bad alignment, many samples",UPN2_094,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),8212,356,8628,"0,0412610107",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,74","14,18"
"low bq, bad alignment, many samples",UPN2_095,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),8038,353,8430,"0,0418742586",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,54","14,18"
"low bq, bad alignment, many samples",UPN2_096,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),7498,323,7867,"0,0410575823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,88","14,16"
"low bq, bad alignment, many samples",UPN2_097,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),9375,386,9831,"0,0392635541",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,8","14,1"
"low bq, bad alignment, many samples",UPN2_098,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),8039,312,8398,"0,0371517028",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,77",14
"low bq, bad alignment, many samples",UPN2_099,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3805,161,3997,"0,0402802102",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,68","14,16"
"low bq, bad alignment, many samples",UPN2_100,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),6364,233,6625,"0,0351698113",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,73","14,17"
"low bq, bad alignment, many samples",UPN2_101,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),7251,275,7586,"0,0362509887",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,73","14,43"
"low bq, bad alignment, many samples",UPN2_102,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),7621,296,7980,"0,0370927318",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,62","14,07"
"low bq, bad alignment, many samples",UPN2_103,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),6659,276,6971,"0,0395925979",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,27","14,34"
"low bq, bad alignment, many samples",UPN2_104,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),8283,328,8647,"0,0379322308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,52","14,12"
"low bq, bad alignment, many samples",UPN2_105,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),7450,302,7782,"0,0388075045",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,67","14,45"
"low bq, bad alignment, many samples",UPN2_106,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),9764,363,10184,"0,0356441477",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,88","14,33"
"low bq, bad alignment, many samples",UPN2_107,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),13131,501,13701,"0,036566674",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,63","14,19"
"low bq, bad alignment, many samples",UPN2_108,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),10491,384,10928,"0,0351390922",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,87","14,14"
"low bq, bad alignment, many samples",UPN2_109,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),10106,423,10594,"0,0399282613",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,71","14,18"
"low bq, bad alignment, many samples",UPN2_110,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),9814,413,10293,"0,0401243564",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"23,02","14,21"
"low bq, bad alignment",UPN2_111,2,25470024,A,C,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys340Gly/c.1018T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),8934,379,9370,"0,0404482391",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,154,Tolerated,"22,67","14,36"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_001,2,25470026,A,C,missense_variant+splice_region_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3489,38,3551,"0,0107012109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,46","15,74"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_015,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),12444,141,12721,"0,0110840343",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"22,75","15,5"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_020,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),5932,61,6044,"0,0100926539",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"22,96","16,85"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_021,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),7509,97,7665,"0,012654925",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,05","16,44"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_002,2,25470026,A,C,missense_variant+splice_region_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4731,73,4833,"0,01510449",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,25","14,89"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_022,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),8294,98,8443,"0,0116072486",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"22,87","15,67"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_023,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),9589,101,9759,"0,010349421",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"22,91","14,94"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_041,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1225,24,1261,"0,0190325139",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,42",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_026,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),11314,133,11520,"0,0115451389",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"22,55","15,41"
"low bq, bad alignment, many samples",UPN2_089,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),7468,242,7753,"0,0312137237",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,65","14,6"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),14953,286,15442,"0,018520917",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,5","15,71"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_028,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),8162,87,8327,"0,0104479404",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"22,57","14,61"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_043,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),10643,173,10950,"0,0157990868",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,86","14,65"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_044,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4502,95,4639,"0,0204785514",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,6",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_029,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),10438,111,10630,"0,0104421449",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,02","14,52"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_030,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),9302,107,9481,"0,0112857294",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"22,88","16,27"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_005,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),1553,24,1589,"0,0151038389",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,36","15,83"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),14675,270,15143,"0,0178300205",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,6","15,03"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_032,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3600,43,3672,"0,0117102397",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"22,98","16,42"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),13281,265,13676,"0,0193770108",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,46","14,87"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_033,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),7499,82,7641,"0,0107315796",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,1","17,29"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_034,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2710,32,2765,"0,0115732369",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"22,52","15,38"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),19599,402,20224,"0,0198773734",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,49","14,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_048,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4971,92,5124,"0,0179547229",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,66","14,62"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_035,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),9287,95,9470,"0,010031679",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,02","16,89"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_006,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),2831,51,2894,"0,0176226676",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,51","15,14"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),13907,288,14403,"0,0199958342",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,63","15,8"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),13593,207,13960,"0,0148280802",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,39","15,51"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_037,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),17195,183,17534,"0,0104368655",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"22,68","15,42"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),11087,175,11401,"0,0153495307",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,76","15,6"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),11337,243,11720,"0,0207337884",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,31","15,19"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_039,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),15063,162,15337,"0,0105626915",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"22,59","15,86"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),13636,283,14092,"0,0200823162",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,28","15,06"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),9269,183,9568,"0,0191262542",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,48","14,4"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_007,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),11703,151,11958,"0,0126275297",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,92","15,02"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_008,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),16513,245,16885,"0,01450992",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,28","15,67"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_009,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),14722,220,15049,"0,0146189116",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,54","14,98"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_010,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),7878,122,8061,"0,0151345987",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,33","15,41"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_011,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),8981,135,9199,"0,0146755082",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,69","15,3"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),14609,295,15064,"0,0195831121",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,42","15,53"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),5469,86,5613,"0,0153215749",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,65","15,08"
"low bq, bad alignment, many samples",UPN2_090,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),6696,168,6903,"0,0243372447",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,77","14,99"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),12775,285,13194,"0,0216007276",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,52","15,88"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_058,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),11340,221,11715,"0,0188647034",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,59","14,47"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_012,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),5943,72,6065,"0,0118713932",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,8","14,18"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_013,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3048,47,3115,"0,0150882825",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,62","15,79"
"low bq, bad alignment, many samples",UPN2_091,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),6880,190,7125,"0,0266666667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,49","14,29"
"low bq, bad alignment, many samples",UPN2_092,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),4087,122,4235,"0,0288075561",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,44","14,42"
"low bq, bad alignment, many samples",UPN2_093,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),5529,171,5747,"0,0297546546",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,7","15,14"
"low bq, bad alignment, many samples",UPN2_094,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),8338,248,8629,"0,0287402944",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,46","14,32"
"low bq, bad alignment, many samples",UPN2_095,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),8097,267,8431,"0,0316688412",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,22","14,44"
"low bq, bad alignment, many samples",UPN2_096,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),7571,246,7868,"0,0312658871",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,6","14,46"
"low bq, bad alignment, many samples",UPN2_097,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),9512,287,9831,"0,0291933679",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,69","14,9"
"low bq, bad alignment, many samples",UPN2_098,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),8117,218,8398,"0,0259585616",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,35","14,57"
"low bq, bad alignment, many samples",UPN2_099,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),3889,93,3997,"0,0232674506",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,3","15,13"
"low bq, bad alignment, many samples",UPN2_100,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),6431,162,6627,"0,0244454504",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,51","14,81"
"low bq, bad alignment, many samples",UPN2_101,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),7342,213,7585,"0,0280817403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,56","14,58"
"low bq, bad alignment, many samples",UPN2_102,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),7735,217,7987,"0,0271691499",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,57","14,78"
"low bq, bad alignment, many samples",UPN2_103,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),6761,171,6971,"0,0245301965",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,05","15,16"
"low bq, bad alignment, many samples",UPN2_104,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),8371,233,8649,"0,0269395306",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,36","14,94"
"low bq, bad alignment, many samples",UPN2_105,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),7505,236,7783,"0,0303224978",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,38","14,91"
"low bq, bad alignment, many samples",UPN2_106,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),9850,293,10185,"0,0287677958",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,48","14,09"
"low bq, bad alignment, many samples",UPN2_107,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),13236,390,13711,"0,0284443148",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,39","14,41"
"low bq, bad alignment, many samples",UPN2_108,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),10587,282,10930,"0,0258005489",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,56","14,93"
"low bq, bad alignment, many samples",UPN2_109,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),10204,319,10595,"0,0301085418",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,47","14,49"
"low bq, bad alignment, many samples",UPN2_110,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),9891,348,10296,"0,0337995338",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,62","17,01"
"low bq, bad alignment",UPN2_111,2,25470026,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val339Gly/c.1016T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|9|C),9045,278,9373,"0,0296596607",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"23,43","14,52"
"inspected, not in 2nd illumina, not in 454",UPN2_006,2,25470464,G,T,stop_gained(HIGH|NONSENSE|tCa/tAa|p.Ser337*/c.1010C>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|T),1274,59,1336,"0,0441616766",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,7","34,22"
"inspected, many artifacts",UPN2_090,2,25470465,A,G,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser337Pro/c.1009T>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),1872,24,1896,"0,0126582278",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,04",Deleterious,"0,001",Damaging,"35,58","35,12"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,25470482,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe331Cys/c.992T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2488,32,2531,"0,012643224",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,42",Deleterious,0,Damaging,"28,05","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25470482,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe331Cys/c.992T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1487,26,1515,"0,0171617162",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,42",Deleterious,0,Damaging,"28,03","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25470482,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe331Cys/c.992T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1487,29,1520,"0,0190789474",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,42",Deleterious,0,Damaging,"27,72","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25470482,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe331Cys/c.992T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1557,33,1596,"0,0206766917",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,42",Deleterious,0,Damaging,"28,18","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25470482,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe331Cys/c.992T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2174,39,2222,"0,0175517552",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,42",Deleterious,0,Damaging,"27,84","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_066,2,25470482,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe331Cys/c.992T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1338,21,1362,"0,0154185022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,42",Deleterious,0,Damaging,"28,78","16,29"
"low bq, low freq, many artifacts, many samples",UPN2_067,2,25470482,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe331Cys/c.992T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1235,20,1258,"0,0158982512",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,42",Deleterious,0,Damaging,"28,1","15,75"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25470482,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe331Cys/c.992T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1732,26,1759,"0,0147811256",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,42",Deleterious,0,Damaging,"28,22","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25470482,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe331Cys/c.992T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2045,34,2083,"0,0163226116",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,42",Deleterious,0,Damaging,"28,12","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25470482,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe331Cys/c.992T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1537,24,1567,"0,0153158902",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,42",Deleterious,0,Damaging,"28,19","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25470482,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe331Cys/c.992T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1482,24,1511,"0,0158835208",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,42",Deleterious,0,Damaging,"28,02",14
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25470482,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe331Cys/c.992T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2713,41,2776,"0,0147694524",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,42",Deleterious,0,Damaging,"28,78","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25470482,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe331Cys/c.992T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1288,20,1315,"0,0152091255",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,42",Deleterious,0,Damaging,"27,97",14
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25470482,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe331Cys/c.992T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1394,31,1427,"0,0217238963",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,42",Deleterious,0,Damaging,"28,12","16,77"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25470482,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe331Cys/c.992T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1871,36,1916,"0,0187891441",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,42",Deleterious,0,Damaging,"27,83","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25470482,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe331Cys/c.992T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1132,24,1160,"0,0206896552",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,42",Deleterious,0,Damaging,"28,42","15,83"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25470482,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe331Cys/c.992T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1725,25,1760,"0,0142045455",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,42",Deleterious,0,Damaging,"28,82",14
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25470482,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe331Cys/c.992T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2662,44,2722,"0,0161645849",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,42",Deleterious,0,Damaging,"28,25","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25470482,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe331Cys/c.992T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1719,21,1747,"0,0120206068",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,42",Deleterious,0,Damaging,"28,41","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25470482,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe331Cys/c.992T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1617,28,1649,"0,0169799879",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,42",Deleterious,0,Damaging,"27,37","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25470482,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe331Cys/c.992T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1302,20,1325,"0,0150943396",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,42",Deleterious,0,Damaging,"27,32",14
"low bq, low freq, many artifacts, many samples",UPN2_085,2,25470482,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe331Cys/c.992T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1262,25,1297,"0,0192752506",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,42",Deleterious,0,Damaging,"28,31","15,6"
"low bq, low freq, many artifacts, many samples",UPN2_087,2,25470482,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe331Cys/c.992T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2012,40,2061,"0,0194080543",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,42",Deleterious,0,Damaging,"27,81","14,45"
"low bq, low freq, many artifacts",UPN2_088,2,25470482,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe331Cys/c.992T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1695,29,1730,"0,0167630058",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,42",Deleterious,0,Damaging,"28,62","14,45"
"low bq, low freq, many artifacts",UPN2_084,2,25470483,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe331Val/c.991T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1301,21,1325,"0,0158490566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,57",Deleterious,0,Damaging,"30,57","18,19"
"inspected, many artifacts",UPN2_056,2,25470486,A,G,missense_variant(MODERATE|MISSENSE|Tgg/Cgg|p.Trp330Arg/c.988T>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),1504,25,1539,"0,0162443145",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-11,03",Deleterious,0,Damaging,"31,65","32,68"
"low bq, low freq, many artifacts, many samples",UPN2_014,2,25470489,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met329Leu/c.985A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),3025,39,3071,"0,0126994464",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,27,Damaging,"31,96","18,31"
"low bq, low freq, many artifacts, many samples",UPN2_015,2,25470489,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met329Leu/c.985A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),5555,72,5644,"0,01275691",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,27,Damaging,"31,81","16,83"
"low bq, low freq, many artifacts, many samples",UPN2_017,2,25470489,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met329Leu/c.985A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),1557,21,1582,"0,0132743363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,27,Damaging,"32,12",14
"low bq, low freq, many artifacts, many samples",UPN2_018,2,25470489,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met329Leu/c.985A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),2843,41,2896,"0,0141574586",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,27,Damaging,"32,03","16,98"
"low bq, low freq, many artifacts, many samples",UPN2_019,2,25470489,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met329Leu/c.985A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),2955,36,3002,"0,0119920053",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,27,Damaging,"32,03","16,08"
"low bq, low freq, many artifacts, many samples",UPN2_020,2,25470489,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met329Leu/c.985A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),1960,30,1996,"0,0150300601",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,27,Damaging,"31,93","16,8"
"low bq, low freq, many artifacts, many samples",UPN2_021,2,25470489,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met329Leu/c.985A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),2815,49,2879,"0,0170197985",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,27,Damaging,"31,87","17,65"
"low bq, low freq, many artifacts, many samples",UPN2_002,2,25470489,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met329Leu/c.985A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),2363,24,2391,"0,0100376412",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,27,Damaging,"32,07",14
"low bq, low freq, many artifacts, many samples",UPN2_022,2,25470489,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met329Leu/c.985A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),3059,32,3102,"0,0103159252",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,27,Damaging,"31,87","16,06"
"low bq, low freq, many artifacts, many samples",UPN2_024,2,25470489,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met329Leu/c.985A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),1606,21,1640,"0,012804878",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,27,Damaging,"31,92",18
"low bq, low freq, many artifacts, many samples",UPN2_025,2,25470489,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met329Leu/c.985A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),5286,90,5396,"0,0166790215",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,27,Damaging,"31,78","19,4"
"low bq, low freq, many artifacts, many samples",UPN2_026,2,25470489,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met329Leu/c.985A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),3429,48,3486,"0,0137693632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,27,Damaging,"31,88","19,33"
"low bq, low freq, many artifacts, many samples",UPN2_027,2,25470489,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met329Leu/c.985A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),4781,62,4863,"0,0127493317",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,27,Damaging,"31,93","18,19"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,25470489,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met329Leu/c.985A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),5225,67,5312,"0,0126129518",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,27,Damaging,"32,2",19
"low bq, low freq, many artifacts, many samples",UPN2_028,2,25470489,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met329Leu/c.985A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),2916,56,2983,"0,0187730473",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,27,Damaging,"31,82","18,64"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,25470489,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met329Leu/c.985A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),4615,58,4697,"0,0123483074",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,27,Damaging,"32,04","20,31"
"low bq, many samples",UPN2_044,2,25470489,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met329Leu/c.985A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),1721,44,1774,"0,0248027057",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,27,Damaging,"32,08",25
"low bq, low freq, many artifacts, many samples",UPN2_030,2,25470489,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met329Leu/c.985A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),3934,52,3998,"0,0130065033",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,27,Damaging,"31,86","17,79"
"low bq, low freq, many artifacts, many samples",UPN2_031,2,25470489,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met329Leu/c.985A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),2786,48,2845,"0,0168717047",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,27,Damaging,"31,56","16,94"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,25470489,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met329Leu/c.985A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),7026,83,7171,"0,0115743969",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,27,Damaging,"32,13","20,05"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,25470489,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met329Leu/c.985A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),6332,78,6432,"0,0121268657",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,27,Damaging,"31,96","18,86"
"low bq, low freq, many artifacts, many samples",UPN2_033,2,25470489,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met329Leu/c.985A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),3145,36,3189,"0,0112888053",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,27,Damaging,"31,89","18,36"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,25470489,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met329Leu/c.985A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),8733,90,8871,"0,0101454177",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,27,Damaging,"31,97","16,74"
"low bq, low freq, many artifacts, many samples",UPN2_048,2,25470489,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met329Leu/c.985A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),1692,26,1729,"0,015037594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,27,Damaging,"32,2","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_036,2,25470489,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met329Leu/c.985A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),3806,46,3867,"0,0118955262",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,27,Damaging,"32,04","20,59"
"low bq, low freq, many artifacts, many samples",UPN2_006,2,25470489,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met329Leu/c.985A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),1297,23,1323,"0,0173847317",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,27,Damaging,"31,53","18,61"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,25470489,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met329Leu/c.985A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),5164,54,5247,"0,0102915952",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,27,Damaging,"32,1","17,85"
"low bq, low freq, many artifacts, many samples",UPN2_037,2,25470489,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met329Leu/c.985A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),5615,86,5725,"0,0150218341",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,27,Damaging,"31,91","15,95"
"low bq, low freq, many artifacts, many samples",UPN2_038,2,25470489,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met329Leu/c.985A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),6679,87,6796,"0,012801648",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,27,Damaging,"31,93","16,69"
"low bq, low freq, many artifacts, many samples",UPN2_039,2,25470489,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met329Leu/c.985A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),4925,60,5008,"0,0119808307",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,27,Damaging,"32,06","16,67"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,25470489,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met329Leu/c.985A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),6840,84,6967,"0,0120568394",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,27,Damaging,"32,06","19,51"
"low bq, low freq, many artifacts, many samples",UPN2_007,2,25470489,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met329Leu/c.985A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),5444,78,5534,"0,0140946874",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,27,Damaging,"31,75","15,82"
"low bq, low freq, many artifacts, many samples",UPN2_008,2,25470489,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met329Leu/c.985A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),7718,117,7864,"0,0148779247",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,27,Damaging,"31,85","17,4"
"low bq, low freq, many artifacts, many samples",UPN2_009,2,25470489,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met329Leu/c.985A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),5997,92,6095,"0,0150943396",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,27,Damaging,"31,7","15,53"
"low bq, low freq, many artifacts, many samples",UPN2_010,2,25470489,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met329Leu/c.985A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),3879,51,3943,"0,012934314",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,27,Damaging,"31,82","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_011,2,25470489,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met329Leu/c.985A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),4296,72,4381,"0,016434604",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,27,Damaging,"31,85","16,12"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,25470489,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met329Leu/c.985A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),7761,92,7890,"0,0116603295",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,27,Damaging,"32,12","17,45"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,25470489,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met329Leu/c.985A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),3869,46,3925,"0,0117197452",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,27,Damaging,"32,12","17,26"
"low bq, low freq, many artifacts, many samples",UPN2_012,2,25470489,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met329Leu/c.985A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),2186,32,2228,"0,0143626571",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,27,Damaging,"31,68","22,28"
"low bq, low freq, many artifacts, many samples",UPN2_040,2,25470489,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met329Leu/c.985A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),1820,32,1862,"0,0171858217",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,27,Damaging,"31,81","17,75"
"low bq, low freq, many artifacts",UPN2_083,2,25470489,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met329Leu/c.985A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),1621,20,1649,"0,0121285628",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,27,Damaging,"32,33","23,5"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25470491,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val328Gly/c.983T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2184,25,2222,"0,0112511251",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,0,Damaging,"29,3","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25470491,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val328Gly/c.983T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1888,21,1915,"0,0109660574",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,0,Damaging,"29,7","16,05"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25470491,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val328Gly/c.983T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1296,24,1325,"0,0181132075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,0,Damaging,"29,12","14,54"
"low bq, low freq, many artifacts",UPN2_087,2,25470491,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val328Gly/c.983T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2030,23,2061,"0,0111596312",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,0,Damaging,"29,2","15,96"
"inspected, many artifacts",UPN2_048,2,25470494,C,T,stop_gained(HIGH|NONSENSE|tGg/tAg|p.Trp327*/c.980G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|T),1689,38,1728,"0,0219907407",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,NA,NA,NA,NA,"31,59","32,53"
"inspected, many artifacts",UPN2_084,2,25470494,C,T,stop_gained(HIGH|NONSENSE|tGg/tAg|p.Trp327*/c.980G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|T),1292,33,1325,"0,0249056604",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,NA,NA,NA,NA,"30,37","31,55"
"inspected, many artifacts",UPN2_097,2,25470498,G,A,missense_variant(MODERATE|MISSENSE|Cgc/Tgc|p.Arg326Cys/c.976C>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),3307,51,3377,"0,0151021617",0,0,0,0,1,0,0,1,2,NO,NO,COSM4169721,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NA,NO,NO,"-5,97",Deleterious,0,Damaging,"31,53","31,25"
"inspected, many artifacts",UPN2_056,2,25470501,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr325Ala/c.973A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1501,23,1529,"0,0150425114",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,048",Damaging,"34,54","35,09"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,25470504,C,G,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly324Arg/c.970G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),1587,20,1609,"0,0124300808",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,99",Deleterious,1,Damaging,"30,37",14
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25470504,C,G,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly324Arg/c.970G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),3028,34,3069,"0,0110785272",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,99",Deleterious,1,Damaging,"30,66","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25470504,C,G,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly324Arg/c.970G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),2915,39,2966,"0,0131490223",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,99",Deleterious,1,Damaging,"30,42","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25470504,C,G,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly324Arg/c.970G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),2534,37,2585,"0,0143133462",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,99",Deleterious,1,Damaging,"30,43","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25470504,C,G,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly324Arg/c.970G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),5270,56,5342,"0,0104829652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,99",Deleterious,1,Damaging,"30,43","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25470504,C,G,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly324Arg/c.970G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),3383,44,3438,"0,0127981385",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,99",Deleterious,1,Damaging,"30,47","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25470504,C,G,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly324Arg/c.970G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),2553,32,2593,"0,0123409179",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,99",Deleterious,1,Damaging,"30,48","14,22"
"low bq, low freq, many artifacts",UPN2_085,2,25470504,C,G,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly324Arg/c.970G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),2508,28,2543,"0,0110106174",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,99",Deleterious,1,Damaging,"30,41","14,25"
"inspected, many artifacts",UPN2_006,2,25470513,C,T,missense_variant(MODERATE|MISSENSE|Gca/Aca|p.Ala321Thr/c.961G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|T),2588,27,2618,"0,0103132162",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,"0,011",Damaging,"34,22","31,81"
"inspected, many artifacts",UPN2_056,2,25470519,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser319Gly/c.955A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2967,38,3029,"0,0125453945",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,81",Neutral,"0,162",Tolerated,"31,8","32,29"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25470519,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser319Arg/c.955A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),2926,30,2974,"0,0100874243",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,81",Neutral,681,Tolerated,"30,89","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25470519,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser319Arg/c.955A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),2964,31,3011,"0,0102955829",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,81",Neutral,681,Tolerated,"30,55","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_067,2,25470519,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser319Arg/c.955A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),2449,25,2486,"0,0100563154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,81",Neutral,681,Tolerated,"30,98","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25470519,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser319Arg/c.955A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),2053,21,2082,"0,0100864553",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,81",Neutral,681,Tolerated,"30,93",14
"low bq, low freq, many artifacts",UPN2_069,2,25470519,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser319Arg/c.955A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),3425,37,3478,"0,0106382979",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,81",Neutral,681,Tolerated,"30,94","15,08"
"inspected, many artifacts",UPN2_041,2,25470521,C,A,missense_variant(MODERATE|MISSENSE|cGg/cTg|p.Arg318Leu/c.953G>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),308,22,332,"0,0662650602",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,7",Deleterious,"0,089",Tolerated,"31,56","32,68"
"low freq, many artifacts",UPN2_012,2,25470521,C,T,missense_variant(MODERATE|MISSENSE|cGg/cAg|p.Arg318Gln/c.953G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|T),4340,44,4392,"0,0100182149",0,0,0,0,1,0,0,0,1,NO,NO,COSM4312146,large_intestine. oesophagus,"1,1",NO,NO,NO,NO,NO,NO,"-1,68",Neutral,13,Damaging,"33,38","32,02"
"inspected, many artifacts",UPN2_071,2,25470524,C,T,missense_variant(MODERATE|MISSENSE|gGc/gAc|p.Gly317Asp/c.950G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|T),4065,43,4128,"0,0104166667",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,098",Tolerated,"32,67","27,42"
"low bq, low freq, many artifacts",UPN2_062,2,25470527,G,C,missense_variant(MODERATE|MISSENSE|aCg/aGg|p.Thr316Arg/c.947C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2974,33,3013,"0,010952539",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,04",Neutral,9,Damaging,"30,78","21,76"
"inspected, many artifacts",UPN2_078,2,25470528,T,A,missense_variant(MODERATE|MISSENSE|Acg/Tcg|p.Thr316Ser/c.946A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),3677,46,3787,"0,0121468181",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,"0,139",Tolerated,"28,79","25,72"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,25470528,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr316Pro/c.946A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),4886,92,5007,"0,018374276",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,21,Damaging,"28,86","15,54"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25470528,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr316Pro/c.946A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),2900,55,2977,"0,0184749748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,21,Damaging,"28,92","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25470528,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr316Pro/c.946A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),2937,44,2999,"0,0146715572",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,21,Damaging,"29,06",14
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25470528,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr316Pro/c.946A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),2932,54,3013,"0,0179223365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,21,Damaging,"28,51",14
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25470528,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr316Pro/c.946A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),3101,60,3171,"0,0189214759",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,21,Damaging,"28,97","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25470528,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr316Pro/c.946A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),4275,72,4393,"0,0163897109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,21,Damaging,"28,74","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,25470528,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr316Pro/c.946A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),1575,34,1616,"0,021039604",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,21,Damaging,"28,9","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_066,2,25470528,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr316Pro/c.946A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),2600,51,2666,"0,0191297824",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,21,Damaging,"29,09","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_067,2,25470528,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr316Pro/c.946A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),2437,37,2487,"0,0148773623",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,21,Damaging,"28,68","16,14"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25470528,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr316Pro/c.946A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),2037,38,2082,"0,0182516811",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,21,Damaging,"29,12","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25470528,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr316Pro/c.946A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),3422,55,3483,"0,0157909848",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,21,Damaging,"29,07","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,25470528,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr316Pro/c.946A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),1892,32,1937,"0,0165203924",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,21,Damaging,"28,43","15,31"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25470528,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr316Pro/c.946A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),4049,54,4128,"0,0130813953",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,21,Damaging,"28,77","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25470528,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr316Pro/c.946A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),2998,60,3081,"0,0194741967",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,21,Damaging,"28,99","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25470528,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr316Pro/c.946A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),2908,54,2984,"0,0180965147",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,21,Damaging,"28,75","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,25470528,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr316Pro/c.946A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),1919,36,1957,"0,0183955033",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,21,Damaging,"28,93","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25470528,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr316Pro/c.946A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),5346,105,5482,"0,0191535936",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,21,Damaging,"29,21","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25470528,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr316Pro/c.946A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),2544,44,2605,"0,016890595",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,21,Damaging,"29,08","15,5"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25470528,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr316Pro/c.946A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),2766,50,2826,"0,0176928521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,21,Damaging,"28,65",14
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25470528,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr316Pro/c.946A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),2240,42,2299,"0,0182688125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,21,Damaging,"28,84","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25470528,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr316Pro/c.946A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),3409,53,3482,"0,0152211373",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,21,Damaging,"29,07","14,13"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25470528,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr316Pro/c.946A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),5267,90,5390,"0,0166975881",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,21,Damaging,"28,99","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25470528,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr316Pro/c.946A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),3381,62,3459,"0,0179242556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,21,Damaging,"29,08","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25470528,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr316Pro/c.946A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),3193,59,3267,"0,0180593817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,21,Damaging,"28,91",14
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25470528,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr316Pro/c.946A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),2563,41,2612,"0,0156967841",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,21,Damaging,"28,86",14
"low bq, low freq, many artifacts, many samples",UPN2_085,2,25470528,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr316Pro/c.946A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),2483,54,2553,"0,0211515864",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,21,Damaging,"28,83","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_086,2,25470528,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr316Pro/c.946A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),2358,41,2410,"0,0170124481",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,21,Damaging,"28,59",14
"low bq, low freq, many artifacts, many samples",UPN2_087,2,25470528,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr316Pro/c.946A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),3992,62,4079,"0,0151998039",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,21,Damaging,"28,7","15,39"
"low bq, low freq, many artifacts",UPN2_088,2,25470528,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr316Pro/c.946A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),3334,62,3413,"0,0181658365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,21,Damaging,"28,92","14,61"
"inspected, many artifacts",UPN2_090,2,25470529,C,T,missense_variant(MODERATE|MISSENSE|atG/atA|p.Met315Ile/c.945G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|T),3620,53,3678,"0,0144100054",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,67",Neutral,"0,231",Tolerated,"33,22","32,51"
"inspected, many artifacts",UPN2_012,2,25470529,C,T,missense_variant(MODERATE|MISSENSE|atG/atA|p.Met315Ile/c.945G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|T),4313,62,4385,"0,0141391106",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,67",Neutral,"0,231",Tolerated,"33,73","32,97"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25470530,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met315Arg/c.944T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2923,38,2977,"0,012764528",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,315,Tolerated,"29,72","17,24"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25470530,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met315Arg/c.944T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2946,38,3000,"0,0126666667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,315,Tolerated,"29,89","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25470530,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met315Arg/c.944T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2934,45,3013,"0,0149352805",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,315,Tolerated,"29,46","15,73"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25470530,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met315Arg/c.944T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3110,46,3171,"0,0145064648",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,315,Tolerated,"29,99","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25470530,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met315Arg/c.944T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),4305,62,4393,"0,0141133622",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,315,Tolerated,"29,8","14,11"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,25470530,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met315Arg/c.944T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1583,26,1616,"0,0160891089",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,315,Tolerated,"30,17","16,15"
"low bq, low freq, many artifacts, many samples",UPN2_066,2,25470530,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met315Arg/c.944T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2604,33,2666,"0,0123780945",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,315,Tolerated,"30,1","15,73"
"low bq, low freq, many artifacts, many samples",UPN2_067,2,25470530,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met315Arg/c.944T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2444,30,2487,"0,0120627262",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,315,Tolerated,"30,41","15,57"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25470530,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met315Arg/c.944T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2041,31,2082,"0,0148895293",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,315,Tolerated,"29,57",15
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25470530,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met315Arg/c.944T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3424,41,3482,"0,011774842",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,315,Tolerated,"30,15","16,05"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,25470530,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met315Arg/c.944T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1893,29,1937,"0,0149716056",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,315,Tolerated,"29,71","15,55"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25470530,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met315Arg/c.944T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),4039,56,4128,"0,0135658915",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,315,Tolerated,"29,92","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25470530,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met315Arg/c.944T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3026,31,3083,"0,0100551411",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,315,Tolerated,"29,89","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25470530,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met315Arg/c.944T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2926,46,2984,"0,0154155496",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,315,Tolerated,"29,88",14
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25470530,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met315Arg/c.944T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5393,59,5483,"0,0107605326",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,315,Tolerated,"30,2","14,12"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25470530,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met315Arg/c.944T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2561,37,2605,"0,0142034549",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,315,Tolerated,"29,64","16,14"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25470530,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met315Arg/c.944T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2780,38,2826,"0,0134465676",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,315,Tolerated,"29,65","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25470530,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met315Arg/c.944T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3704,67,3788,"0,017687434",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,315,Tolerated,"29,97","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25470530,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met315Arg/c.944T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2265,23,2299,"0,0100043497",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,315,Tolerated,"30,48",14
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25470530,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met315Arg/c.944T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5293,58,5391,"0,0107586719",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,315,Tolerated,"29,81","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25470530,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met315Arg/c.944T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3407,36,3459,"0,0104076323",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,315,Tolerated,"30,04","14,19"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25470530,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met315Arg/c.944T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3198,49,3267,"0,0149984695",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,315,Tolerated,"29,67","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25470530,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met315Arg/c.944T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2572,29,2613,"0,0110983544",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,315,Tolerated,"29,86","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,25470530,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met315Arg/c.944T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2510,29,2553,"0,0113591853",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,315,Tolerated,"29,86","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_086,2,25470530,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met315Arg/c.944T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2367,33,2410,"0,0136929461",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,315,Tolerated,"29,68","14,82"
"low bq, low freq, many artifacts",UPN2_087,2,25470530,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met315Arg/c.944T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3988,61,4079,"0,0149546457",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,315,Tolerated,"29,86","18,31"
"inspected, many artifacts, low freq",UPN2_072,2,25470531,TC,T,frameshift_variant(HIGH||tgg/|p.Trp314fs/c.942delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|T),3033,34,3082,"0,0110317975",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,8",NA
"inspected, many artifacts",UPN2_067,2,25470532,C,T,stop_gained(HIGH|NONSENSE|tgG/tgA|p.Trp314*/c.942G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|T),2444,32,2487,"0,0128669079",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,NA,NA,NA,NA,"32,8","33,03"
"low bq, low freq, many artifacts, many samples",UPN2_010,2,25470534,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp314Gly/c.940T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),7657,91,7790,"0,0116816431",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,29",Neutral,175,Tolerated,"30,42","15,78"
"low bq, low freq, many artifacts, many samples",UPN2_056,2,25470534,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp314Gly/c.940T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3011,31,3065,"0,0101141925",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,29",Neutral,175,Tolerated,"30,46","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,25470534,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp314Gly/c.940T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),4906,58,5008,"0,0115814696",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,29",Neutral,175,Tolerated,"30,52","16,83"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25470534,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp314Gly/c.940T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2899,38,2977,"0,012764528",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,29",Neutral,175,Tolerated,"30,46","14,18"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25470534,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp314Gly/c.940T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2941,40,3000,"0,0133333333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,29",Neutral,175,Tolerated,"30,36","15,68"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25470534,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp314Gly/c.940T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2933,48,3013,"0,0159309658",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,29",Neutral,175,Tolerated,"30,25","15,56"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25470534,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp314Gly/c.940T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3087,59,3172,"0,0186002522",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,29",Neutral,175,Tolerated,"30,19","15,56"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25470534,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp314Gly/c.940T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),4275,73,4395,"0,0166097838",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,29",Neutral,175,Tolerated,"30,23","15,85"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,25470534,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp314Gly/c.940T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1574,35,1616,"0,0216584158",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,29",Neutral,175,Tolerated,"30,29","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_066,2,25470534,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp314Gly/c.940T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2597,45,2667,"0,0168728909",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,29",Neutral,175,Tolerated,"30,74","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_067,2,25470534,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp314Gly/c.940T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2431,40,2487,"0,0160836349",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,29",Neutral,175,Tolerated,"30,52","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25470534,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp314Gly/c.940T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2041,25,2082,"0,0120076849",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,29",Neutral,175,Tolerated,"30,21","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25470534,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp314Gly/c.940T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3401,66,3482,"0,0189546238",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,29",Neutral,175,Tolerated,"30,51","15,7"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,25470534,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp314Gly/c.940T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1886,36,1937,"0,0185854414",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,29",Neutral,175,Tolerated,"30,2","16,08"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25470534,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp314Gly/c.940T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),4027,65,4128,"0,015746124",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,29",Neutral,175,Tolerated,"30,41","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25470534,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp314Gly/c.940T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3004,53,3083,"0,0171910477",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,29",Neutral,175,Tolerated,"30,4","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25470534,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp314Gly/c.940T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2927,39,2984,"0,0130697051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,29",Neutral,175,Tolerated,"30,54","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,25470534,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp314Gly/c.940T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1915,22,1957,"0,0112416965",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,29",Neutral,175,Tolerated,"30,12",15
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25470534,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp314Gly/c.940T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5348,77,5482,"0,0140459686",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,29",Neutral,175,Tolerated,"30,71","15,57"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25470534,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp314Gly/c.940T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2547,49,2605,"0,0188099808",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,29",Neutral,175,Tolerated,"30,53","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25470534,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp314Gly/c.940T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2759,51,2828,"0,0180339463",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,29",Neutral,175,Tolerated,"30,3","16,14"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25470534,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp314Gly/c.940T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3695,58,3789,"0,015307469",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,29",Neutral,175,Tolerated,"30,19","15,69"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25470534,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp314Gly/c.940T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2253,34,2300,"0,0147826087",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,29",Neutral,175,Tolerated,"30,53","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25470534,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp314Gly/c.940T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3395,68,3483,"0,0195233994",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,29",Neutral,175,Tolerated,"30,56","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25470534,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp314Gly/c.940T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5280,90,5391,"0,0166944908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,29",Neutral,175,Tolerated,"30,28","15,39"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25470534,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp314Gly/c.940T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3376,59,3458,"0,0170618855",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,29",Neutral,175,Tolerated,"30,55","16,83"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25470534,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp314Gly/c.940T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3178,62,3267,"0,0189776553",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,29",Neutral,175,Tolerated,"30,32","16,02"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25470534,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp314Gly/c.940T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2550,40,2612,"0,0153139357",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,29",Neutral,175,Tolerated,"30,37","16,12"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,25470534,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp314Gly/c.940T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2489,48,2553,"0,0188014101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,29",Neutral,175,Tolerated,"30,28","15,73"
"low bq, low freq, many artifacts, many samples",UPN2_086,2,25470534,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp314Gly/c.940T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2353,35,2409,"0,0145288501",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,29",Neutral,175,Tolerated,"29,97","15,31"
"low bq, low freq, many artifacts, many samples",UPN2_087,2,25470534,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp314Gly/c.940T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3994,61,4079,"0,0149546457",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,29",Neutral,175,Tolerated,"30,1","15,25"
"low bq, low freq, many artifacts",UPN2_088,2,25470534,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp314Gly/c.940T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3363,37,3415,"0,0108345534",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,29",Neutral,175,Tolerated,"30,44","15,03"
"inspected, many artifacts",UPN2_006,2,25470536,C,T,stop_gained(HIGH|NONSENSE|tGg/tAg|p.Trp313*/c.938G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|T),2557,55,2619,"0,0210003818",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,02","28,69"
"inspected, many artifacts",UPN2_048,2,25470537,A,G,missense_variant(MODERATE|MISSENSE|Tgg/Cgg|p.Trp313Arg/c.937T>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),3190,44,3257,"0,0135093644",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,96",Deleterious,"0,002",Damaging,"31,43","31,48"
"low bq, low freq, many artifacts",UPN2_046,2,25470537,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp313Arg/c.937T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|T),12476,153,12687,"0,0120595886",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,96",Deleterious,2,Damaging,"31,28","24,61"
"low bq, low freq, many artifacts, many samples",UPN2_022,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),6056,66,6165,"0,0107055961",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"30,18","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),10305,112,10482,"0,0106849838",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"29,84","14,18"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3457,37,3516,"0,010523322",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"29,62","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),17246,199,17585,"0,0113164629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"29,66","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),10146,107,10335,"0,0103531688",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"29,79","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),9889,103,10100,"0,0101980198",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"29,7","14,19"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),13525,145,13767,"0,0105324326",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"29,76","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),7809,87,7952,"0,0109406439",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"29,63","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_009,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),11834,124,12057,"0,010284482",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"30,13","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_056,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3018,32,3065,"0,0104404568",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"29,76","16,66"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),7553,93,7696,"0,0120841996",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"29,87","14,34"
"low bq, many samples",UPN2_059,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),4858,124,5008,"0,0247603834",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"28,93","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_012,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),4313,48,4398,"0,0109140518",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"30,55","15,98"
"low bq, many samples",UPN2_060,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2893,66,2976,"0,0221774194",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"28,78","15,65"
"low bq, low freq, many artifacts, many samples",UPN2_013,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2129,25,2164,"0,0115526802",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"30,56","14,28"
"low bq, many samples",UPN2_061,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2902,75,3001,"0,0249916694",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"28,92","14,52"
"low bq, many samples",UPN2_062,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2913,82,3014,"0,0272063703",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"28,76","15,11"
"low bq, many samples",UPN2_063,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3079,75,3172,"0,0236443884",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"28,82","15,32"
"low bq, many samples",UPN2_064,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),4254,120,4395,"0,0273037543",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"29,06","15,32"
"low bq, many samples",UPN2_065,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1573,41,1616,"0,0253712871",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"29,4","16,51"
"low bq, many samples",UPN2_066,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2593,62,2669,"0,023229674",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"29,07","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_067,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2414,52,2487,"0,0209087254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"28,98","14,38"
"low bq, many samples",UPN2_068,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2028,51,2082,"0,0244956772",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"28,84","14,51"
"low bq, many samples",UPN2_069,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3378,92,3482,"0,0264215968",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"29,02","14,5"
"low bq, many samples",UPN2_070,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1868,52,1937,"0,0268456376",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"28,62","14,77"
"low bq, many samples",UPN2_071,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3984,114,4127,"0,0276229707",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"28,99","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3010,64,3084,"0,0207522698",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"28,81","14,94"
"low bq, many samples",UPN2_073,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2898,69,2983,"0,0231310761",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"28,77","14,86"
"low bq, many samples",UPN2_074,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1895,44,1957,"0,0224833929",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"29,35","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5352,108,5485,"0,0196900638",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"29,24","16,12"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2537,54,2605,"0,0207293666",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"29,02","14,63"
"low bq, many samples",UPN2_077,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2732,74,2827,"0,0261761585",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"28,98","15,35"
"low bq, many samples",UPN2_078,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3683,92,3790,"0,0242744063",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"28,87","15,09"
"low bq, many samples",UPN2_079,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2222,64,2300,"0,027826087",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"29,09","14,2"
"low bq, many samples",UPN2_080,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3361,100,3484,"0,0287026406",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,29,"15,21"
"low bq, many samples",UPN2_081,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5234,126,5390,"0,0233766234",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"29,05","15,05"
"low bq, many samples",UPN2_082,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3355,84,3458,"0,024291498",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"28,93","15,42"
"low bq, many samples",UPN2_083,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3173,73,3270,"0,022324159",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"28,92","15,42"
"low bq, many samples",UPN2_084,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2518,70,2612,"0,0267993874",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"28,84","15,43"
"low bq, many samples",UPN2_085,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2483,60,2554,"0,0234925607",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"28,88","15,17"
"low bq, many samples",UPN2_086,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2331,61,2408,"0,0253322259",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"28,64","14,46"
"low bq, many samples",UPN2_087,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3933,114,4079,"0,0279480265",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"28,93","15,25"
"low bq, many samples",UPN2_088,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3326,80,3416,"0,0234192037",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,29,"14,81"
"low bq, low freq, many artifacts",UPN2_096,2,25470540,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser312Ala/c.934T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),6077,66,6160,"0,0107142857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,36,Damaging,"30,53","14,32"
"low bq, low freq, many artifacts",UPN2_070,2,25470542,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val311Gly/c.932T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1898,20,1938,"0,0103199174",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,-5,Deleterious,0,Damaging,"31,16","15,8"
"inspected, many artifacts",UPN2_048,2,25470545,A,T,missense_variant(MODERATE|MISSENSE|aTt/aAt|p.Ile310Asn/c.929T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|T),3198,43,3257,"0,0132023334",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,22",Deleterious,0,Damaging,"32,54","26,12"
"low bq, many samples",UPN2_001,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),3456,80,3538,"0,022611645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,49","16,58"
"low bq, low freq, many artifacts, many samples",UPN2_014,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),5982,103,6101,"0,0168824783",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"31,22","17,12"
"low bq, low freq, many artifacts, many samples",UPN2_015,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),10942,210,11187,"0,0187717887",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"31,17","15,56"
"low bq, low freq, many artifacts, many samples",UPN2_016,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),5163,92,5268,"0,0174639332",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"31,38","16,24"
"low bq, low freq, many artifacts, many samples",UPN2_017,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),3067,63,3143,"0,0200445434",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,96","17,25"
"low bq, low freq, many artifacts, many samples",UPN2_018,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),5625,114,5761,"0,0197882312",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"31,14","15,62"
"low bq, low freq, many artifacts, many samples",UPN2_019,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),5846,106,5962,"0,0177792687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"31,31","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_020,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),3856,81,3965,"0,0204287516",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"31,08","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_021,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),5577,123,5710,"0,0215411559",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"31,16","16,23"
"low bq, low freq, many artifacts, many samples",UPN2_002,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),4660,92,4764,"0,0193115029",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,66","16,5"
"low bq, low freq, many artifacts, many samples",UPN2_003,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),1019,21,1042,"0,0201535509",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,93","16,76"
"low bq, many samples",UPN2_022,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),6014,137,6165,"0,0222222222",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"31,13","16,57"
"low bq, low freq, many artifacts, many samples",UPN2_023,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),6946,121,7085,"0,0170783345",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"31,22","16,77"
"low bq, low freq, many artifacts, many samples",UPN2_024,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),3164,69,3240,"0,0212962963",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"31,12","18,55"
"low bq, low freq, many artifacts, many samples",UPN2_025,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),10469,195,10702,"0,0182208933",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"31,09","15,78"
"low bq, low freq, many artifacts, many samples",UPN2_026,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),6760,145,6924,"0,0209416522",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"31,22","16,12"
"low bq, many samples",UPN2_004,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),1021,27,1052,"0,0256653992",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,5",14
"low bq, low freq, many artifacts, many samples",UPN2_027,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),9456,172,9658,"0,0178090702",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"31,08","15,77"
"low bq, low freq, many artifacts, many samples",UPN2_089,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),5156,65,5243,"0,0123974824",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,75","15,69"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),10236,212,10488,"0,0202135774",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,53","16,39"
"low bq, low freq, many artifacts, many samples",UPN2_028,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),5780,106,5898,"0,017972194",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"31,01","15,25"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),9053,151,9261,"0,0163049347",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,56","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),3442,62,3516,"0,0176336746",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,66","16,15"
"low bq, low freq, many artifacts, many samples",UPN2_029,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),6992,149,7155,"0,0208245982",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"31,06","16,08"
"low bq, many samples",UPN2_030,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),7744,175,7937,"0,022048633",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"31,17","16,36"
"low bq, many samples",UPN2_031,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),5483,139,5638,"0,0246541327",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"31,02","17,04"
"low bq, many samples",UPN2_005,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),1132,28,1160,"0,024137931",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,57",14
"low bq, low freq, many artifacts, many samples",UPN2_045,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),13827,303,14189,"0,0213545704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,57","16,7"
"low bq, low freq, many artifacts, many samples",UPN2_032,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),2354,34,2402,"0,0141548709",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"31,09","16,71"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),12411,249,12692,"0,0196186574",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,43","15,53"
"low bq, low freq, many artifacts, many samples",UPN2_033,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),6166,134,6320,"0,0212025316",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,95","16,92"
"low bq, low freq, many artifacts, many samples",UPN2_034,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),2074,36,2123,"0,0169571361",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"31,02","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),17152,359,17593,"0,0204058432",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,48","16,22"
"low bq, low freq, many artifacts, many samples",UPN2_048,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),3187,65,3261,"0,019932536",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,56","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_035,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),6105,117,6246,"0,0187319885",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"31,36","15,57"
"low bq, low freq, many artifacts, many samples",UPN2_036,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),7542,149,7711,"0,019323045",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"31,09","15,72"
"low bq, many samples",UPN2_006,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),2545,62,2621,"0,0236550935",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,5",16
"low bq, low freq, many artifacts, many samples",UPN2_049,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),6872,123,7018,"0,0175263608",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,48","15,98"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),10047,216,10339,"0,020891769",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,49","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_037,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),11112,221,11367,"0,0194422451",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"31,14",17
"low bq, low freq, many artifacts, many samples",UPN2_051,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),10462,188,10709,"0,0175553273",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,7","16,77"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),9897,168,10103,"0,0166287241",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,54","16,29"
"low bq, low freq, many artifacts, many samples",UPN2_038,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),13200,258,13487,"0,0191295321",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"31,22","17,34"
"low bq, low freq, many artifacts, many samples",UPN2_039,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),9729,181,9960,"0,0181726908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"31,19","16,44"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),13457,262,13771,"0,0190254883",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,49","15,63"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),7792,153,7956,"0,0192307692",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,51","17,53"
"low bq, many samples",UPN2_007,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),10704,262,10998,"0,0238225132",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,52","15,95"
"low bq, many samples",UPN2_008,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),15161,366,15562,"0,0235188279",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,6","16,13"
"low bq, many samples",UPN2_009,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),11678,334,12055,"0,0277063459",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,59","15,84"
"low bq, low freq, many artifacts, many samples",UPN2_010,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),7583,171,7785,"0,0219653179",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,57","15,86"
"low bq, many samples",UPN2_011,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),8443,237,8708,"0,0272163528",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,85","15,72"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),15257,286,15603,"0,0183298084",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,6","16,13"
"low bq, low freq, many artifacts, many samples",UPN2_056,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),2993,63,3066,"0,0205479452",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,7","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_090,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),3614,61,3682,"0,0165670831",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"31,02",14
"low bq, low freq, many artifacts, many samples",UPN2_057,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),8038,172,8239,"0,0208763199",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,69","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),7520,154,7703,"0,0199922108",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,74","15,86"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),4895,86,5010,"0,0171656687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,61","15,23"
"low bq, many samples",UPN2_012,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),4273,110,4399,"0,0250056831",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,64","15,51"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),2918,48,2979,"0,0161127895",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,56","14,27"
"low bq, many samples",UPN2_040,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),3602,86,3696,"0,0232683983",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,83","17,02"
"low bq, many samples",UPN2_013,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),2110,51,2164,"0,0235674677",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,85",14
"low bq, low freq, many artifacts, many samples",UPN2_091,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),4179,48,4238,"0,0113260972",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,75","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_092,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),2803,32,2849,"0,0112320112",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"31,05",14
"low bq, low freq, many artifacts, many samples",UPN2_093,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),2394,30,2427,"0,0123609394",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,83",14
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),2943,48,3001,"0,0159946684",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,77",14
"low bq, many samples",UPN2_062,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),2931,67,3014,"0,0222295952",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,29","15,45"
"low bq, many samples",UPN2_063,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),3090,71,3171,"0,0223904131",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,66","16,85"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),4277,85,4397,"0,0193313623",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,53","16,75"
"low bq, many samples",UPN2_065,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),1574,37,1616,"0,0228960396",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,34","17,7"
"low bq, low freq, many artifacts, many samples",UPN2_066,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),2619,51,2675,"0,0190654206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,56","15,92"
"low bq, low freq, many artifacts, many samples",UPN2_067,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),2446,38,2488,"0,0152733119",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,57","15,53"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),2032,34,2082,"0,0163304515",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,47","16,32"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),3418,55,3485,"0,0157819225",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,78","15,76"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),1905,28,1939,"0,0144404332",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,47",14
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),4033,74,4127,"0,0179307003",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,66","16,01"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),3023,48,3086,"0,0155541154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"31,01","15,02"
"low bq, many samples",UPN2_073,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),2915,68,2984,"0,0227882038",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,65","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),1922,35,1960,"0,0178571429",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,81","15,51"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),5371,104,5491,"0,0189400838",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,65","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),2555,36,2605,"0,0138195777",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,48",14
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),2784,32,2829,"0,0113114175",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,62","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),3710,72,3793,"0,0189823359",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,44","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),2256,35,2299,"0,0152240104",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,75","16,4"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),3412,59,3484,"0,016934558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,53","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),5289,95,5390,"0,0176252319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,42","15,53"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),3387,67,3459,"0,01936976",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,49","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),3205,54,3269,"0,0165188131",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,24","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),2544,55,2617,"0,021016431",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,67","15,73"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),2495,53,2554,"0,0207517619",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,4","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_086,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),2358,48,2409,"0,0199252802",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,24","15,1"
"low bq, many samples",UPN2_087,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),3980,92,4082,"0,0225379716",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,32","15,68"
"low bq, low freq, many artifacts, many samples",UPN2_088,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),3333,67,3417,"0,0196078431",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,38","15,31"
"low bq, low freq, many artifacts, many samples",UPN2_094,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),6514,72,6619,"0,0108777761",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,84","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_095,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),5172,85,5273,"0,0161198559",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,63","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_096,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),6072,63,6158,"0,0102305943",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,79","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_097,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),6624,68,6708,"0,0101371497",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,55","15,75"
"low bq, low freq, many artifacts, many samples",UPN2_098,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),4474,48,4533,"0,0105890139",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,69","16,29"
"low bq, low freq, many artifacts, many samples",UPN2_100,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),5378,65,5455,"0,0119156737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,93","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_101,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),4232,43,4280,"0,010046729",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,79","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_102,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),6261,75,6340,"0,011829653",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,93","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_103,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),5503,61,5572,"0,0109475951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,79","16,1"
"low bq, low freq, many artifacts, many samples",UPN2_104,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),6668,73,6761,"0,0107972193",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,97","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_106,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),7738,83,7857,"0,0105638284",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,81","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_107,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),9272,112,9415,"0,0118959108",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,83","16,7"
"low bq, low freq, many artifacts, many samples",UPN2_108,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),8102,90,8214,"0,0109569028",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"31,1","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_109,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),7257,80,7352,"0,0108813928",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,74","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_110,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),8247,97,8361,"0,0116014831",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,83","15,27"
"low bq, low freq, many artifacts",UPN2_111,2,25470546,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile310Phe/c.928A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),5987,89,6093,"0,014606926",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,39",Deleterious,1,Damaging,"30,74","16,09"
"inspected, many artifacts",UPN2_077,2,25470551,C,T,missense_variant(MODERATE|MISSENSE|gGc/gAc|p.Gly308Asp/c.923G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|T),2786,30,2828,"0,0106082037",0,0,0,0,1,0,0,1,2,NO,NO,COSM4169957,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,"0,001",Damaging,"32,02","29,67"
"inspected, many artifacts",UPN2_062,2,25470557,C,T,stop_gained(HIGH|NONSENSE|tGg/tAg|p.Trp306*/c.917G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|T),2938,67,3018,"0,0222001325",0,0,0,0,1,1,0,1,3,NO,NO,COSM249798,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,69","29,46"
"low bq, low freq, many artifacts, many samples",UPN2_015,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),10970,124,11181,"0,0110902424",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"28,76","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_018,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5654,58,5758,"0,010072942",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"28,69","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_002,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),4676,55,4764,"0,0115449202",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,04","15,53"
"low bq, low freq, many artifacts, many samples",UPN2_022,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),6037,70,6170,"0,0113452188",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"28,71","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_025,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),10504,110,10697,"0,010283257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"28,69","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_026,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),6805,74,6923,"0,0106890077",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"28,54","15,39"
"low bq, low freq, many artifacts, many samples",UPN2_027,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),9481,116,9656,"0,012013256",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"28,64","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_089,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5175,53,5241,"0,0101125739",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"30,89","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),10206,157,10487,"0,0149709164",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,33","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),9040,115,9257,"0,0124230312",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,33","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3333,46,3517,"0,013079329",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,47",14
"low bq, low freq, many artifacts, many samples",UPN2_029,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),7025,73,7154,"0,0102040816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"28,81","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),13871,173,14187,"0,0121942624",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,38","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_032,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2357,33,2402,"0,0137385512",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"28,81","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),12426,165,12696,"0,0129962193",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,27","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_033,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),6210,64,6313,"0,0101378109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"28,9",14
"low bq, low freq, many artifacts, many samples",UPN2_034,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2077,28,2122,"0,013195099",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"28,74","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),17225,233,17605,"0,0132348765",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,17","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_006,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2555,43,2622,"0,0163996949",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,22","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),6887,80,7018,"0,011399259",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,31","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),10104,120,10341,"0,0116042936",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,42","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_037,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),11186,119,11381,"0,0104560232",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"28,65","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),10506,119,10705,"0,0111163008",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,45","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),9841,140,10107,"0,0138517859",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,31","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),13490,197,13767,"0,0143095809",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,35","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),7801,96,7954,"0,012069399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,32","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_007,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),10787,136,10997,"0,0123670092",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,28","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_008,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),15280,212,15576,"0,0136106831",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,13","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_009,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),11844,160,12068,"0,0132582035",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,21","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_010,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),7641,111,7788,"0,0142526965",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,24","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_011,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),8544,123,8708,"0,0141249426",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,24","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),15242,211,15607,"0,0135195745",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,27","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_056,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3015,39,3066,"0,0127201566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,41","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_090,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3621,38,3681,"0,0103232817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"31,12","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),8070,86,8234,"0,0104444984",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,4","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),7490,94,7636,"0,01231011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,28","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),4884,98,5010,"0,0195608782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,42","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2891,65,2980,"0,0218120805",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,36","15,48"
"low bq, low freq, many artifacts, many samples",UPN2_040,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3620,39,3694,"0,0105576611",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"28,5","16,33"
"low bq, low freq, many artifacts, many samples",UPN2_013,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2130,22,2168,"0,0101476015",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,31",16
"low bq, low freq, many artifacts, many samples",UPN2_091,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),4174,47,4239,"0,0110875206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"31,01","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_092,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2803,33,2851,"0,011574886",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"31,01","15,45"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2923,58,2999,"0,0193397799",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,29","14,22"
"low bq, many samples",UPN2_062,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2919,79,3017,"0,0261849519",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,33","14,97"
"low bq, many samples",UPN2_063,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3079,83,3172,"0,0261664565",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,43",15
"low bq, many samples",UPN2_064,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),4244,102,4395,"0,0232081911",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,28","14,13"
"low bq, many samples",UPN2_065,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1565,43,1614,"0,0266418835",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,15","14,91"
"low bq, many samples",UPN2_066,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2590,68,2672,"0,0254491018",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,46","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_067,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2422,49,2485,"0,0197183099",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,14","15,59"
"low bq, many samples",UPN2_068,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2029,46,2080,"0,0221153846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,41","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3370,75,3484,"0,0215269805",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,42","15,56"
"low bq, many samples",UPN2_070,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1884,47,1939,"0,0242392986",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,14","15,64"
"low bq, many samples",UPN2_071,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3960,120,4127,"0,0290768112",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,26","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3024,52,3085,"0,0168557536",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,18","15,44"
"low bq, many samples",UPN2_073,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2893,67,2985,"0,0224455611",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,11","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1916,35,1962,"0,0178389399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,39","15,63"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5334,113,5487,"0,0205941316",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,52","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2541,57,2608,"0,0218558282",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"28,99","15,68"
"low bq, many samples",UPN2_077,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2747,66,2825,"0,0233628319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,34","15,59"
"low bq, many samples",UPN2_078,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3679,89,3793,"0,0234642763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,28","15,13"
"low bq, many samples",UPN2_079,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2217,58,2298,"0,0252393386",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,35","15,33"
"low bq, many samples",UPN2_080,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3360,98,3481,"0,0281528296",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,21","15,01"
"low bq, many samples",UPN2_081,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5203,151,5384,"0,0280460624",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,36","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3373,62,3458,"0,017929439",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,3","15,29"
"low bq, many samples",UPN2_083,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3158,78,3269,"0,0238605078",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,04","14,26"
"low bq, many samples",UPN2_084,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2530,59,2601,"0,0226835832",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,08","15,61"
"low bq, many samples",UPN2_085,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2478,65,2554,"0,0254502741",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,28","14,91"
"low bq, many samples",UPN2_086,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2319,75,2407,"0,0311591192",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,15","14,79"
"low bq, many samples",UPN2_087,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3948,104,4076,"0,025515211",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,27","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_088,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3320,75,3413,"0,0219748022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"29,24","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_097,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),6618,68,6707,"0,0101386611",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"30,92","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_098,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),4471,47,4533,"0,0103684094",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,31,"14,28"
"low bq, low freq, many artifacts, many samples",UPN2_102,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),6245,68,6340,"0,0107255521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"30,97","14,56"
"low bq, low freq, many artifacts",UPN2_106,2,25470558,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp306Gly/c.916T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),7749,81,7855,"0,0103119032",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,48",Deleterious,0,Damaging,"31,06","14,81"
"inspected, many artifacts",UPN2_044,2,25470558,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp306Arg/c.916T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|T),3333,136,3517,"0,0386693204",0,0,0,0,0,1,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-11,46",Deleterious,0,Damaging,"29,47","30,38"
"low bq, low freq, many artifacts, many samples",UPN2_021,2,25470566,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe303Cys/c.908T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5608,64,5706,"0,0112162636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,14",Deleterious,0,Damaging,"30,02","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,25470566,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe303Cys/c.908T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),10269,109,10478,"0,0104027486",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,14",Deleterious,0,Damaging,"29,86","15,59"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,25470566,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe303Cys/c.908T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3445,46,3515,"0,013086771",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,14",Deleterious,0,Damaging,"29,78","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,25470566,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe303Cys/c.908T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),13909,146,14180,"0,0102961918",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,14",Deleterious,0,Damaging,"29,94","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,25470566,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe303Cys/c.908T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),12473,127,12694,"0,0100047266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,14",Deleterious,0,Damaging,"29,73","14,8"
"low bq, many samples",UPN2_059,2,25470566,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe303Cys/c.908T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),4834,148,5003,"0,0295822506",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,14",Deleterious,0,Damaging,"28,33",15
"low bq, many samples",UPN2_060,2,25470566,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe303Cys/c.908T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2866,86,2978,"0,0288784419",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,14",Deleterious,0,Damaging,"28,73","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_040,2,25470566,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe303Cys/c.908T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3625,46,3694,"0,0124526259",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,14",Deleterious,0,Damaging,"30,09",14
"low bq, low freq, many artifacts, many samples",UPN2_092,2,25470566,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe303Cys/c.908T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2800,31,2849,"0,0108810109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,14",Deleterious,0,Damaging,"30,26","15,29"
"low bq, many samples",UPN2_061,2,25470566,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe303Cys/c.908T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2889,96,2994,"0,0320641283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,14",Deleterious,0,Damaging,"28,79","14,68"
"low bq, many samples",UPN2_062,2,25470566,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe303Cys/c.908T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2891,93,3012,"0,030876494",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,14",Deleterious,0,Damaging,"28,24","14,87"
"low bq, many samples",UPN2_063,2,25470566,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe303Cys/c.908T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3039,111,3170,"0,0350157729",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,14",Deleterious,0,Damaging,"28,32","14,77"
"low bq, many samples",UPN2_064,2,25470566,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe303Cys/c.908T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),4211,137,4387,"0,03122863",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,14",Deleterious,0,Damaging,"28,32","14,47"
"low bq, many samples",UPN2_065,2,25470566,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe303Cys/c.908T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1553,48,1607,"0,0298693217",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,14",Deleterious,0,Damaging,"28,58","15,31"
"low bq, many samples",UPN2_066,2,25470566,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe303Cys/c.908T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2569,79,2666,"0,0296324081",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,14",Deleterious,0,Damaging,"28,56","14,85"
"low bq, many samples",UPN2_067,2,25470566,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe303Cys/c.908T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2395,76,2486,"0,0305711987",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,14",Deleterious,0,Damaging,"28,6","14,84"
"low bq, many samples",UPN2_068,2,25470566,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe303Cys/c.908T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1998,68,2076,"0,0327552987",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,14",Deleterious,0,Damaging,"28,44","14,78"
"low bq, many samples",UPN2_069,2,25470566,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe303Cys/c.908T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3357,112,3479,"0,032193159",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,14",Deleterious,0,Damaging,"28,58","14,87"
"low bq, many samples",UPN2_070,2,25470566,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe303Cys/c.908T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1861,63,1940,"0,0324742268",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,14",Deleterious,0,Damaging,"28,38","15,44"
"low bq, many samples",UPN2_071,2,25470566,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe303Cys/c.908T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3958,138,4119,"0,0335032775",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,14",Deleterious,0,Damaging,"28,46","14,92"
"low bq, many samples",UPN2_072,2,25470566,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe303Cys/c.908T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2932,120,3078,"0,0389863548",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,14",Deleterious,0,Damaging,"28,39","14,76"
"low bq, many samples",UPN2_073,2,25470566,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe303Cys/c.908T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2866,85,2980,"0,0285234899",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,14",Deleterious,0,Damaging,"28,31","14,76"
"low bq, many samples",UPN2_074,2,25470566,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe303Cys/c.908T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1899,55,1958,"0,0280898876",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,14",Deleterious,0,Damaging,"28,47","14,95"
"low bq, many samples",UPN2_075,2,25470566,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe303Cys/c.908T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5299,154,5482,"0,0280919372",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,14",Deleterious,0,Damaging,"28,6","14,58"
"low bq, many samples",UPN2_076,2,25470566,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe303Cys/c.908T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2508,82,2604,"0,0314900154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,14",Deleterious,0,Damaging,"28,41","14,72"
"low bq, many samples",UPN2_077,2,25470566,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe303Cys/c.908T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2719,96,2823,"0,0340063762",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,14",Deleterious,0,Damaging,"28,82","14,69"
"low bq, many samples",UPN2_078,2,25470566,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe303Cys/c.908T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3628,129,3786,"0,0340729002",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,14",Deleterious,0,Damaging,"28,51","14,26"
"low bq, many samples",UPN2_079,2,25470566,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe303Cys/c.908T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2225,57,2299,"0,0247933884",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,14",Deleterious,0,Damaging,"28,68","14,7"
"low bq, many samples",UPN2_080,2,25470566,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe303Cys/c.908T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3391,101,3515,"0,0287339972",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,14",Deleterious,0,Damaging,"28,53","14,78"
"low bq, many samples",UPN2_081,2,25470566,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe303Cys/c.908T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5163,176,5372,"0,0327624721",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,14",Deleterious,0,Damaging,"28,44","15,86"
"low bq, many samples",UPN2_082,2,25470566,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe303Cys/c.908T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3305,113,3446,"0,0327916425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,14",Deleterious,0,Damaging,"28,69","14,88"
"low bq, many samples",UPN2_083,2,25470566,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe303Cys/c.908T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3140,107,3262,"0,032801962",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,14",Deleterious,0,Damaging,"28,53","14,93"
"low bq, many samples",UPN2_084,2,25470566,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe303Cys/c.908T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2509,78,2610,"0,0298850575",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,14",Deleterious,0,Damaging,"28,39","15,37"
"low bq, many samples",UPN2_085,2,25470566,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe303Cys/c.908T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2463,76,2550,"0,0298039216",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,14",Deleterious,0,Damaging,"28,32","15,2"
"low bq, many samples",UPN2_086,2,25470566,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe303Cys/c.908T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2324,71,2406,"0,0295095594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,14",Deleterious,0,Damaging,"28,3","14,94"
"low bq, many samples",UPN2_087,2,25470566,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe303Cys/c.908T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3907,136,4070,"0,0334152334",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,14",Deleterious,0,Damaging,"28,35","14,96"
"low bq, many samples",UPN2_088,2,25470566,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe303Cys/c.908T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3289,92,3409,"0,0269873863",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,14",Deleterious,0,Damaging,"28,54","15,12"
"low bq, low freq, many artifacts",UPN2_095,2,25470566,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe303Cys/c.908T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5211,54,5295,"0,0101983003",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,14",Deleterious,0,Damaging,"29,93","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,25470567,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe303Val/c.907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),4895,81,5001,"0,0161967606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,2,Damaging,"30,21","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25470567,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe303Val/c.907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2905,49,2977,"0,016459523",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,2,Damaging,"30,35","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25470567,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe303Val/c.907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2940,44,2993,"0,0147009689",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,2,Damaging,"30,4","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25470567,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe303Val/c.907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2948,57,3011,"0,0189305878",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,2,Damaging,"29,91","16,23"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25470567,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe303Val/c.907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3080,67,3169,"0,0211423162",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,2,Damaging,"30,03","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25470567,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe303Val/c.907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),4294,71,4385,"0,0161915621",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,2,Damaging,"30,31","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,25470567,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe303Val/c.907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1570,25,1607,"0,0155569384",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,2,Damaging,"30,51","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_066,2,25470567,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe303Val/c.907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2620,38,2666,"0,0142535634",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,2,Damaging,"30,26","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_067,2,25470567,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe303Val/c.907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2423,40,2486,"0,0160901046",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,2,Damaging,"30,38","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25470567,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe303Val/c.907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2033,37,2076,"0,017822736",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,2,Damaging,"30,26","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25470567,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe303Val/c.907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3403,69,3479,"0,0198332854",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,2,Damaging,"30,33","15,61"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,25470567,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe303Val/c.907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1897,36,1940,"0,018556701",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,2,Damaging,"30,2","16,94"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25470567,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe303Val/c.907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),4046,61,4118,"0,014813016",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,2,Damaging,"30,16","15,39"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25470567,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe303Val/c.907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3001,59,3078,"0,0191682911",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,2,Damaging,"30,43","15,53"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25470567,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe303Val/c.907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2915,53,2979,"0,0177912051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,2,Damaging,"30,15","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,25470567,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe303Val/c.907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1931,25,1958,"0,0127681307",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,2,Damaging,"30,31","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25470567,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe303Val/c.907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5383,75,5481,"0,0136836344",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,2,Damaging,"30,23","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25470567,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe303Val/c.907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2552,33,2604,"0,0126728111",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,2,Damaging,"30,12","16,12"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25470567,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe303Val/c.907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2740,48,2823,"0,0170031881",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,2,Damaging,"30,31","15,6"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25470567,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe303Val/c.907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3713,53,3786,"0,0139989435",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,2,Damaging,"29,87","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25470567,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe303Val/c.907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2257,37,2299,"0,0160939539",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,2,Damaging,"30,49","16,73"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25470567,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe303Val/c.907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3452,57,3515,"0,0162162162",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,2,Damaging,"30,28","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25470567,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe303Val/c.907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5254,84,5370,"0,0156424581",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,2,Damaging,"30,35","15,25"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25470567,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe303Val/c.907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3389,45,3444,"0,0130662021",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,2,Damaging,"30,08","15,56"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25470567,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe303Val/c.907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3167,71,3259,"0,0217858239",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,2,Damaging,"30,32","15,9"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25470567,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe303Val/c.907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2527,57,2609,"0,0218474511",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,2,Damaging,"30,32",15
"low bq, low freq, many artifacts, many samples",UPN2_085,2,25470567,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe303Val/c.907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2504,38,2549,"0,014907807",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,2,Damaging,"30,15","15,58"
"low bq, low freq, many artifacts, many samples",UPN2_086,2,25470567,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe303Val/c.907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2355,38,2405,"0,0158004158",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,2,Damaging,"30,04","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_087,2,25470567,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe303Val/c.907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3948,76,4068,"0,0186823992",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,2,Damaging,"30,09","15,04"
"low bq, low freq, many artifacts",UPN2_088,2,25470567,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe303Val/c.907T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3348,46,3409,"0,0134936932",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,2,Damaging,"30,4","15,26"
"low bq, many samples",UPN2_001,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3458,86,3551,"0,02421853",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,47","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_014,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5959,94,6074,"0,0154757985",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,72","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_015,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),10909,191,11121,"0,0171747145",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,65","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_016,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5164,75,5248,"0,0142911585",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,78","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_017,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3080,36,3129,"0,0115052733",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,75",14
"low bq, low freq, many artifacts, many samples",UPN2_018,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5636,88,5739,"0,0153336818",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,86","14,08"
"low bq, low freq, many artifacts, many samples",UPN2_019,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5844,89,5948,"0,0149630128",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,8","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_020,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3887,66,3965,"0,0166456494",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,88",14
"low bq, low freq, many artifacts, many samples",UPN2_021,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5590,72,5673,"0,0126916975",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,81","14,1"
"low bq, many samples",UPN2_002,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),4608,112,4728,"0,0236886633",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,64","14,26"
"low bq, many samples",UPN2_003,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1019,26,1047,"0,0248328558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,75",14
"low bq, low freq, many artifacts, many samples",UPN2_022,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),6018,112,6143,"0,0182321341",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,8",14
"low bq, low freq, many artifacts, many samples",UPN2_023,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),6930,117,7060,"0,016572238",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,76","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_024,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3155,59,3224,"0,0183002481",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,55",14
"low bq, low freq, many artifacts, many samples",UPN2_025,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),10462,182,10659,"0,0170747725",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,69","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_026,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),6786,97,6894,"0,014070206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,79","14,13"
"low bq, many samples",UPN2_004,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1021,26,1049,"0,02478551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,28,"14,85"
"low bq, low freq, many artifacts, many samples",UPN2_027,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),9458,152,9619,"0,0158020584",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,77","14,35"
"low bq, many samples",UPN2_089,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5084,118,5224,"0,0225880551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,69","14,56"
"low bq, many samples",UPN2_042,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),10159,232,10425,"0,0222541966",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,67","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_028,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5768,87,5868,"0,0148261759",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,71","14,23"
"low bq, many samples",UPN2_043,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),9022,209,9259,"0,022572632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,66","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3417,65,3506,"0,0185396463",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,53",14
"low bq, low freq, many artifacts, many samples",UPN2_029,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),6978,127,7112,"0,0178571429",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,89","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_030,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),7762,120,7898,"0,0151937199",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,72","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_031,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5504,103,5618,"0,0183339267",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,52","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_005,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1127,21,1153,"0,0182133565",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,57",14
"low bq, low freq, many artifacts, many samples",UPN2_045,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),13782,306,14130,"0,021656051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,5","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_032,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2355,35,2392,"0,014632107",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,3",14
"low bq, low freq, many artifacts, many samples",UPN2_046,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),12325,259,12630,"0,02050673",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,44","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_033,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),6129,128,6280,"0,0203821656",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,51","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_034,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2061,43,2110,"0,0203791469",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,82","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),17089,380,17524,"0,0216845469",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,44","14,26"
"low bq, many samples",UPN2_048,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3165,75,3254,"0,0230485556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,48","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_035,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),6147,84,6237,"0,0134680135",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,72","14,08"
"low bq, low freq, many artifacts, many samples",UPN2_036,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),7543,105,7673,"0,0136843477",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,75","14,21"
"low bq, many samples",UPN2_006,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2526,64,2595,"0,0246628131",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,62","14,2"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),6838,133,6994,"0,0190162997",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,48","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),10021,216,10282,"0,0210075861",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,57","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_037,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),11169,161,11348,"0,014187522",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,73","14,04"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),10467,181,10674,"0,016957092",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,48","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),9913,201,10150,"0,0198029557",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,72","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_038,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),13172,222,13411,"0,0165535754",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,81","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_039,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),9822,145,9984,"0,0145232372",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,81","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),13355,301,13704,"0,02196439",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,58","14,19"
"low bq, many samples",UPN2_054,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),7717,179,7915,"0,0226152874",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,61","14,2"
"low bq, many samples",UPN2_007,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),10668,247,10943,"0,0225715069",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,48","14,03"
"low bq, many samples",UPN2_008,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),15143,344,15509,"0,0221806693",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,39","14,14"
"low bq, many samples",UPN2_009,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),11694,300,12023,"0,024952175",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,55","14,24"
"low bq, many samples",UPN2_010,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),7547,174,7754,"0,022440031",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,52","14,24"
"low bq, many samples",UPN2_011,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),8456,192,8671,"0,0221427748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,45","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),15156,328,15540,"0,0211068211",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,61","14,25"
"low bq, many samples",UPN2_056,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2965,74,3054,"0,0242305174",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,49","15,53"
"low bq, many samples",UPN2_090,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3569,82,3663,"0,0223860224",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,65","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),7989,163,8187,"0,0199096128",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,58","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),7470,157,7641,"0,0205470488",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,43","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),4882,85,4986,"0,0170477337",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,98",14
"low bq, low freq, many artifacts, many samples",UPN2_012,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),4282,83,4400,"0,0188636364",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,32",14
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2911,51,2970,"0,0171717172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,87","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_040,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3590,77,3673,"0,0209637898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,73",14
"low bq, low freq, many artifacts, many samples",UPN2_013,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2109,39,2155,"0,0180974478",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,44",14
"low bq, many samples",UPN2_091,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),4102,93,4203,"0,0221270521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,65","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_092,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2787,45,2837,"0,0158618259",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,76",14
"low bq, low freq, many artifacts, many samples",UPN2_093,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2375,51,2430,"0,0209876543",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,84","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2923,48,2979,"0,0161127895",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"29,3","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2923,54,2988,"0,0180722892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,86","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3098,50,3154,"0,0158528852",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,86","14,26"
"low bq, many samples",UPN2_064,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),4255,97,4365,"0,0222222222",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"29,07","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1567,26,1595,"0,0163009404",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,74",14
"low bq, low freq, many artifacts, many samples",UPN2_066,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2595,45,2650,"0,0169811321",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"29,04","14,29"
"low bq, many samples",UPN2_067,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2412,56,2474,"0,0226354082",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,84","14,23"
"low bq, many samples",UPN2_068,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2011,47,2066,"0,022749274",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"29,02","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3396,58,3462,"0,0167533218",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"29,04",14
"low bq, many samples",UPN2_070,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1883,45,1934,"0,0232678387",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,88","14,29"
"low bq, many samples",UPN2_071,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3984,91,4085,"0,0222766218",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"29,04","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2998,65,3067,"0,0211933485",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,87","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2893,53,2956,"0,0179296346",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,81","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1912,36,1952,"0,018442623",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,76","14,19"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5340,97,5461,"0,0177623146",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,93","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2545,44,2594,"0,0169622205",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,98","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2745,55,2807,"0,0195938725",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"29,14","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3685,72,3768,"0,0191082803",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"29,17",14
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2227,45,2283,"0,0197109067",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"29,07","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3422,68,3500,"0,0194285714",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,29,"14,84"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5208,110,5333,"0,0206262891",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,84","14,43"
"low bq, many samples",UPN2_082,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3337,80,3432,"0,0233100233",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"29,04","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3167,52,3241,"0,0160444307",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,91","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2541,51,2598,"0,019630485",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"29,19","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2481,41,2536,"0,0161671924",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,86",14
"low bq, many samples",UPN2_086,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2315,62,2392,"0,0259197324",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,77","14,42"
"low bq, many samples",UPN2_087,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3947,91,4051,"0,0224635892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,76","14,7"
"low bq, many samples",UPN2_088,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3288,87,3388,"0,0256788666",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,84","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_094,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),6419,132,6573,"0,0200821543",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,62","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_095,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5144,115,5266,"0,0218382074",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,64","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_096,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5969,127,6108,"0,0207924034",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,69","14,1"
"low bq, many samples",UPN2_097,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),6483,161,6668,"0,024145171",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,58","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_098,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),4408,97,4514,"0,0214887018",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,87",14
"low bq, low freq, many artifacts, many samples",UPN2_099,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3042,64,3111,"0,0205721633",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,76","14,11"
"low bq, low freq, many artifacts, many samples",UPN2_100,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5296,106,5428,"0,0195283714",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,66","14,17"
"low bq, many samples",UPN2_101,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),4141,105,4256,"0,0246710526",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,76","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_103,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5428,117,5552,"0,021073487",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,85",14
"low bq, low freq, many artifacts, many samples",UPN2_104,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),6576,138,6731,"0,0205021542",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,77",14
"low bq, low freq, many artifacts, many samples",UPN2_105,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),4550,89,4649,"0,0191439019",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,67","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_106,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),7630,155,7805,"0,0198590647",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,65","14,05"
"low bq, low freq, many artifacts, many samples",UPN2_107,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),9143,175,9356,"0,0187045746",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,65","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_108,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),7995,145,8165,"0,0177587263",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,69","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_109,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),7165,151,7322,"0,0206227807",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,64","14,18"
"low bq, low freq, many artifacts, many samples",UPN2_110,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),8125,174,8314,"0,0209285542",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,65","14,04"
low bq,UPN2_111,2,25470573,G,C,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg301Gly/c.901C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5888,150,6061,"0,0247483914",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,36,Damaging,"28,76","14,12"
"low bq, low freq, many artifacts, many samples",UPN2_001,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3442,67,3539,"0,0189319017",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"28,79","14,1"
"low bq, low freq, many artifacts, many samples",UPN2_014,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5887,100,6022,"0,0166057788",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"28,24","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_015,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),10726,207,11008,"0,0188045058",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"28,36","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_016,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5108,73,5215,"0,0139980825",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"28,17","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_017,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3039,42,3093,"0,0135790495",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"28,37","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_018,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5548,90,5684,"0,0158339198",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"28,35","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_019,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5789,79,5895,"0,0134011874",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"28,3","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_020,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3837,68,3930,"0,017302799",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"28,64","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_021,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5502,82,5627,"0,0145725964",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"28,46","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_002,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),4577,88,4691,"0,0187593264",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"28,75","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_022,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5982,88,6095,"0,014438064",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"28,29","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_023,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),6882,101,7012,"0,0144038791",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"28,13","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_024,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3125,46,3201,"0,0143705092",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"28,05","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_025,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),10375,162,10586,"0,0153032307",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"28,28","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_026,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),6701,91,6835,"0,0133138259",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"28,3","14,43"
"low bq, many samples",UPN2_004,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1018,23,1044,"0,0220306513",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"28,7","15,74"
"low bq, low freq, many artifacts, many samples",UPN2_027,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),9294,156,9549,"0,0163367892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"28,3","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),10193,119,10382,"0,011462146",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"29,25","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_028,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5697,93,5821,"0,0159766363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"28,45","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_029,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),6898,97,7029,"0,0137999715",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"28,29","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_030,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),7674,103,7831,"0,013152854",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"28,35","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_031,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5441,97,5565,"0,0174303684",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"28,19","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),13761,158,14045,"0,011249555",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"29,28","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_032,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2314,33,2366,"0,0139475909",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"28,03","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),12296,138,12556,"0,0109907614",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"29,28","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_033,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),6066,109,6228,"0,0175016057",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"28,26","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_034,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2032,37,2082,"0,0177713737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"28,09","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),17125,208,17433,"0,0119313945",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"29,15","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_035,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),6055,95,6194,"0,0153374233",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"28,51","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_036,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),7472,101,7608,"0,0132754995",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"28,34","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_006,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2522,48,2577,"0,0186263097",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"28,98",14
"low bq, low freq, many artifacts, many samples",UPN2_049,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),6839,78,6971,"0,0111892125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"29,28","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),10035,107,10229,"0,0104604556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"29,37","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_037,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),10983,197,11243,"0,0175220137",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"28,27","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),9883,111,10113,"0,0109759715",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"29,28","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_038,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),13027,182,13303,"0,0136811246",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"28,42","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_039,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),9680,153,9901,"0,0154529845",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"28,33","14,09"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),13412,137,13640,"0,0100439883",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"29,36","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),7734,94,7884,"0,0119228818",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"29,41",14
"low bq, low freq, many artifacts, many samples",UPN2_007,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),10622,203,10887,"0,0186460917",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"28,81","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_008,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),15054,294,15422,"0,0190636753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"28,73","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_009,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),11655,214,11957,"0,0178974659",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"28,77","14,13"
"low bq, low freq, many artifacts, many samples",UPN2_010,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),7511,164,7706,"0,0212821178",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"28,87","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_011,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),8429,129,8619,"0,0149669335",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"28,8","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_056,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2988,34,3045,"0,0111658456",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"29,1","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),7480,88,7617,"0,0115531049",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"29,32","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),4848,60,4935,"0,0121580547",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"29,49","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_012,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),4250,87,4372,"0,0198993596",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"28,46","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2880,48,2939,"0,0163320857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"29,12","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_040,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3556,56,3639,"0,0153888431",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"28,27","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_013,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2100,33,2143,"0,0153989734",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"28,84",14
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2881,60,2953,"0,0203183204",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"29,59","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2890,46,2951,"0,0155879363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"29,11","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3047,46,3112,"0,014781491",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"29,26","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),4213,75,4304,"0,0174256506",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"29,55","14,61"
"low bq, many samples",UPN2_065,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1544,35,1586,"0,0220680958",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"29,36","14,2"
"low bq, low freq, many artifacts, many samples",UPN2_066,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2565,45,2623,"0,0171559283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"29,2","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_067,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2384,43,2448,"0,0175653595",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"29,47","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1997,29,2032,"0,0142716535",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"29,15","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3355,63,3426,"0,0183887916",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"29,5",15
"low bq, many samples",UPN2_070,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1858,45,1913,"0,0235232619",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"29,1","15,87"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3957,67,4035,"0,0166047088",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"29,29","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2948,53,3031,"0,0174859782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"29,11","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2867,46,2927,"0,0157157499",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"29,25","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1895,29,1937,"0,0149716056",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"29,36","17,21"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5304,70,5412,"0,0129342203",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"29,37","15,76"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2495,50,2566,"0,0194855807",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"29,4","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2709,56,2780,"0,0201438849",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"29,29","17,8"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3649,59,3727,"0,0158304266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"29,44","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2220,43,2273,"0,0189177299",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"29,46","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3386,60,3459,"0,0173460538",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"29,53","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5144,93,5282,"0,0176069671",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"29,29","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3335,46,3404,"0,0135135135",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"29,34","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3127,62,3204,"0,0193508115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"29,56","14,87"
"low bq, many samples",UPN2_084,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2502,58,2571,"0,0225593154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"29,49","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2437,52,2507,"0,0207419226",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"29,78","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_086,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2294,48,2370,"0,0202531646",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"29,21","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_087,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3941,42,3999,"0,0105026257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"28,99","14,95"
"low bq, low freq, many artifacts",UPN2_088,2,25470575,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu300Arg/c.899T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3273,67,3359,"0,0199464126",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,17",Deleterious,1,Damaging,"29,59","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_001,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3479,48,3536,"0,0135746606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,71",14
"low bq, low freq, many artifacts, many samples",UPN2_014,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5905,93,6005,"0,0154870941",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,7",14
"low bq, low freq, many artifacts, many samples",UPN2_015,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),10813,149,10977,"0,0135738362",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,57","14,09"
"low bq, low freq, many artifacts, many samples",UPN2_016,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5108,75,5198,"0,0144286264",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,72",14
"low bq, low freq, many artifacts, many samples",UPN2_017,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3043,42,3088,"0,0136010363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,84",14
"low bq, low freq, many artifacts, many samples",UPN2_018,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5568,87,5665,"0,0153574581",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,84","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_019,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5781,89,5877,"0,0151437808",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,78",14
"low bq, low freq, many artifacts, many samples",UPN2_020,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3855,54,3918,"0,0137825421",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,85","14,13"
"low bq, low freq, many artifacts, many samples",UPN2_021,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5530,69,5616,"0,0122863248",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,71","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_002,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),4617,52,4682,"0,0111063648",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,87",14
"low bq, low freq, many artifacts, many samples",UPN2_022,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5989,79,6081,"0,0129912843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,74",14
"low bq, low freq, many artifacts, many samples",UPN2_023,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),6870,110,6992,"0,0157322654",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,72","14,18"
"low bq, low freq, many artifacts, many samples",UPN2_024,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3141,52,3194,"0,016280526",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,65","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_025,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),10373,164,10558,"0,0155332449",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,65","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_026,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),6724,82,6822,"0,0120199355",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,83","14,09"
"low bq, low freq, many artifacts, many samples",UPN2_004,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1019,20,1043,"0,0191754554",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,37",14
"low bq, low freq, many artifacts, many samples",UPN2_027,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),9343,158,9524,"0,0165896682",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,75","14,13"
"low bq, many samples",UPN2_089,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),4976,200,5181,"0,0386025864",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"27,97","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),10147,173,10358,"0,016702066",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,84","14,2"
"low bq, low freq, many artifacts, many samples",UPN2_028,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5719,78,5803,"0,0134413235",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,62",14
"low bq, low freq, many artifacts, many samples",UPN2_043,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),9020,150,9199,"0,0163061202",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,8",14
"low bq, many samples",UPN2_044,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3389,84,3487,"0,0240894752",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,91","14,15"
"low bq, low freq, many artifacts, many samples",UPN2_029,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),6891,97,7012,"0,0138334284",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,79",14
"low bq, low freq, many artifacts, many samples",UPN2_030,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),7652,127,7806,"0,0162695363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,73","14,06"
"low bq, low freq, many artifacts, many samples",UPN2_031,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5439,102,5546,"0,0183916336",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,7",14
"low bq, low freq, many artifacts, many samples",UPN2_045,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),13694,274,14007,"0,0195616477",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,85","14,09"
"low bq, low freq, many artifacts, many samples",UPN2_032,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2327,30,2362,"0,0127011008",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,36","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),12240,247,12529,"0,0197142629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,86","14,11"
"low bq, low freq, many artifacts, many samples",UPN2_033,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),6086,107,6210,"0,0172302738",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,45",14
"low bq, low freq, many artifacts, many samples",UPN2_034,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2043,32,2078,"0,0153994225",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,49",14
"low bq, low freq, many artifacts, many samples",UPN2_047,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),17027,304,17384,"0,0174873447",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,68","14,07"
"low bq, low freq, many artifacts, many samples",UPN2_048,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3154,60,3225,"0,0186046512",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,74",14
"low bq, low freq, many artifacts, many samples",UPN2_035,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),6070,95,6174,"0,0153871072",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,71","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_036,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),7454,115,7581,"0,0151695027",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,76","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_006,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2535,32,2573,"0,0124368442",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,79",14
"low bq, low freq, many artifacts, many samples",UPN2_049,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),6819,122,6952,"0,0175489068",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,73","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),9962,199,10194,"0,019521287",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,82","14,1"
"low bq, low freq, many artifacts, many samples",UPN2_037,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),11047,137,11210,"0,012221231",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,73","14,05"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),10393,173,10604,"0,0163145983",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,89","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),9889,172,10090,"0,0170465808",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,91","14,04"
"low bq, low freq, many artifacts, many samples",UPN2_038,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),13076,169,13272,"0,0127335744",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,65",14
"low bq, low freq, many artifacts, many samples",UPN2_039,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),9754,102,9872,"0,0103322528",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,78","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),13295,252,13602,"0,0185266873",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,86","14,05"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),7716,125,7864,"0,0158952187",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,88",14
"low bq, low freq, many artifacts, many samples",UPN2_007,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),10690,134,10854,"0,012345679",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,54","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_008,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),15160,181,15399,"0,01175401",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,54",14
"low bq, low freq, many artifacts, many samples",UPN2_009,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),11737,150,11932,"0,012571237",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,73","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_010,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),7581,87,7689,"0,0113148654",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,73",14
"low bq, low freq, many artifacts, many samples",UPN2_011,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),8457,114,8599,"0,0132573555",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,65","14,06"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),15104,275,15425,"0,017828201",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,92","14,07"
"low bq, low freq, many artifacts, many samples",UPN2_056,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2974,55,3034,"0,018127884",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,87",14
"low bq, many samples",UPN2_090,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3513,123,3644,"0,0337541164",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,04","14,11"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),7973,130,8125,"0,016",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,87","14,15"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),7427,150,7589,"0,01976545",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,76","14,09"
"low bq, many samples",UPN2_059,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),4709,182,4898,"0,0371580237",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,32",14
"low bq, low freq, many artifacts, many samples",UPN2_012,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),4303,47,4362,"0,0107748739",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,29",14
"low bq, many samples",UPN2_060,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2805,108,2924,"0,0369357045",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,16","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_040,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3575,49,3630,"0,0134986226",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,65","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_013,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2112,24,2141,"0,0112097151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,69","14,54"
"low bq, many samples",UPN2_091,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3990,156,4156,"0,0375360924",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,2","14,04"
"low bq, many samples",UPN2_092,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2729,82,2817,"0,0291089812",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"27,98","14,09"
"low bq, many samples",UPN2_093,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2321,85,2414,"0,0352112676",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,21","14,15"
"low bq, many samples",UPN2_061,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2846,92,2942,"0,0312712441",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,41","14,93"
"low bq, many samples",UPN2_062,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2792,131,2930,"0,0447098976",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,21","14,26"
"low bq, many samples",UPN2_063,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2977,111,3093,"0,0358874879",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,26","14,3"
"low bq, many samples",UPN2_064,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),4124,150,4276,"0,0350795136",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,27","14,19"
"low bq, many samples",UPN2_065,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1499,71,1573,"0,0451366815",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,3",14
"low bq, many samples",UPN2_066,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2495,107,2607,"0,0410433448",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,41","14,31"
"low bq, many samples",UPN2_067,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2343,83,2432,"0,0341282895",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,2","14,57"
"low bq, many samples",UPN2_068,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1946,70,2020,"0,0346534653",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,2","14,54"
"low bq, many samples",UPN2_069,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3285,106,3400,"0,0311764706",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,32",14
"low bq, many samples",UPN2_070,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1820,78,1903,"0,0409879138",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,14","14,26"
"low bq, many samples",UPN2_071,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3855,151,4017,"0,0375902415",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,06","14,7"
"low bq, many samples",UPN2_072,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2882,129,3013,"0,0428144706",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,22","14,44"
"low bq, many samples",UPN2_073,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2788,117,2908,"0,0402338377",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,28","14,31"
"low bq, many samples",UPN2_074,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),1841,80,1927,"0,0415153088",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,21","14,25"
"low bq, many samples",UPN2_075,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5130,220,5365,"0,0410065238",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,28","14,55"
"low bq, many samples",UPN2_076,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2454,95,2551,"0,0372402979",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,28","14,07"
"low bq, many samples",UPN2_077,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2667,96,2768,"0,0346820809",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,3",14
"low bq, many samples",UPN2_078,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3578,123,3705,"0,0331983806",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,37","14,29"
"low bq, many samples",UPN2_079,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2184,70,2258,"0,0310008857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,34","14,47"
"low bq, many samples",UPN2_080,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3304,119,3434,"0,0346534653",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,52","14,5"
"low bq, many samples",UPN2_081,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5052,193,5249,"0,0367689084",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,19","14,53"
"low bq, many samples",UPN2_082,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3217,149,3380,"0,0440828402",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,51","14,36"
"low bq, many samples",UPN2_083,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3064,111,3179,"0,0349166405",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,33","14,36"
"low bq, many samples",UPN2_084,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2465,93,2560,"0,036328125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,23","14,6"
"low bq, many samples",UPN2_085,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2385,101,2491,"0,0405459655",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,38","14,34"
"low bq, many samples",UPN2_086,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2250,99,2354,"0,0420560748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,3","14,14"
"low bq, many samples",UPN2_087,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3827,143,3974,"0,0359838953",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,16","14,23"
"low bq, many samples",UPN2_088,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),3206,130,3343,"0,038887227",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,02","14,45"
"low bq, many samples",UPN2_094,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),6281,232,6519,"0,0355882804",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,11","14,26"
"low bq, many samples",UPN2_095,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5027,176,5212,"0,0337682272",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"27,99","14,11"
"low bq, many samples",UPN2_096,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5850,195,6055,"0,0322047894",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,16","14,13"
"low bq, many samples",UPN2_097,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),6344,237,6600,"0,0359090909",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,05","14,35"
"low bq, many samples",UPN2_098,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),4335,138,4478,"0,0308173292",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,15","14,05"
"low bq, many samples",UPN2_099,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2989,99,3090,"0,032038835",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,18","14,13"
"low bq, many samples",UPN2_100,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5187,192,5382,"0,0356744705",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,18","14,3"
"low bq, many samples",UPN2_101,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),4084,145,4234,"0,0342465753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,09","14,23"
"low bq, many samples",UPN2_103,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5295,195,5502,"0,0354416576",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,27","14,07"
"low bq, many samples",UPN2_104,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),6443,223,6680,"0,0333832335",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,19","14,15"
"low bq, many samples",UPN2_105,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),4459,158,4619,"0,0342065382",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,12","14,04"
"low bq, many samples",UPN2_106,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),7458,277,7750,"0,0357419355",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,22","14,24"
"low bq, many samples",UPN2_107,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),8941,319,9273,"0,034400949",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,21","14,08"
"low bq, many samples",UPN2_108,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),7829,258,8104,"0,0318361303",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,19","14,13"
"low bq, many samples",UPN2_109,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),7016,229,7252,"0,0315774959",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,08","14,75"
"low bq, many samples",UPN2_110,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),7925,299,8232,"0,0363216715",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,21","14,18"
low bq,UPN2_111,2,25470576,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu300Val/c.898C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),5779,218,6010,"0,0362728785",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,138,Tolerated,"28,2","14,31"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_060,2,25470577,T,A,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys299Asn/c.897A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),2806,30,2918,"0,0102810144",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"26,77","16,67"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_070,2,25470577,T,A,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys299Asn/c.897A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),1804,20,1900,"0,0105263158",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"26,62","15,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,2,25470577,T,A,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys299Asn/c.897A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),2628,35,2764,"0,0126628075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"26,84","19,91"
"low bq, low freq, many artifacts, many samples",UPN2_001,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),3453,50,3535,"0,0141442716",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,95","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_014,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),5812,111,5997,"0,0185092546",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,42","14,26"
"low bq, many samples",UPN2_015,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),10610,252,10968,"0,02297593",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,18","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_016,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),5028,114,5191,"0,0219610865",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,47","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_017,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),2997,63,3083,"0,0204346416",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,53","15,73"
"low bq, low freq, many artifacts, many samples",UPN2_018,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),5485,123,5655,"0,0217506631",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,35","14,36"
"low bq, many samples",UPN2_019,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),5665,141,5872,"0,0240122616",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,31","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_020,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),3783,78,3913,"0,0199335548",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,46","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_021,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),5440,115,5612,"0,0204918033",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,42","16,03"
"low bq, low freq, many artifacts, many samples",UPN2_002,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),4562,80,4680,"0,0170940171",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,65","14,18"
"low bq, low freq, many artifacts, many samples",UPN2_003,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),1004,20,1038,"0,0192678227",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,82",14
"low bq, many samples",UPN2_022,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),5851,147,6073,"0,0242054998",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,32","14,51"
"low bq, many samples",UPN2_023,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),6762,156,6985,"0,0223335719",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,35","15,81"
"low bq, many samples",UPN2_024,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),3093,71,3189,"0,0222640326",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,24","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_025,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),10204,226,10548,"0,0214258627",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,48","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_026,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),6589,148,6810,"0,021732746",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,17","14,61"
"low bq, many samples",UPN2_027,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),9179,230,9515,"0,0241723594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,22","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_089,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),5059,84,5172,"0,0162412993",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"28,36","16,39"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),10034,208,10344,"0,0201082753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,97","15,39"
"low bq, many samples",UPN2_028,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),5587,154,5796,"0,0265700483",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,25","15,61"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),8939,158,9188,"0,0171963431",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"28,05","15,42"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),3363,75,3484,"0,0215269805",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,93","15,12"
"low bq, many samples",UPN2_029,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),6751,181,7003,"0,025846066",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,41","15,41"
"low bq, many samples",UPN2_030,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),7544,177,7794,"0,0227097768",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,39","14,88"
"low bq, many samples",UPN2_031,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),5350,129,5538,"0,0232936078",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,31","15,33"
"low bq, many samples",UPN2_005,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),1110,28,1148,"0,0243902439",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,73","16,04"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),13578,243,13985,"0,0173757597",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"28,01","15,13"
"low bq, many samples",UPN2_032,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),2275,53,2356,"0,0224957555",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,04",14
"low bq, low freq, many artifacts, many samples",UPN2_046,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),12158,242,12511,"0,0193429782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,9","15,33"
"low bq, many samples",UPN2_033,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),6008,139,6205,"0,0224012893",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,46","14,92"
"low bq, many samples",UPN2_034,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),1990,66,2075,"0,0318072289",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,15","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),16854,334,17365,"0,0192340916",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"28,06","15,74"
"low bq, low freq, many artifacts, many samples",UPN2_048,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),3151,49,3222,"0,0152079454",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,9","14,82"
"low bq, many samples",UPN2_035,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),5958,138,6164,"0,0223880597",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,52","14,26"
"low bq, many samples",UPN2_036,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),7302,197,7571,"0,0260203408",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,46","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_006,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),2500,42,2570,"0,0163424125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,85",14
"low bq, low freq, many artifacts, many samples",UPN2_049,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),6757,118,6946,"0,0169881946",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"28,07","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),9921,168,10178,"0,0165061898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,98","15,26"
"low bq, many samples",UPN2_037,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),10776,295,11197,"0,0263463428",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,49","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),10329,164,10596,"0,0154775387",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"28,14","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),9758,191,10071,"0,018965346",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,28,"14,85"
"low bq, low freq, many artifacts, many samples",UPN2_038,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),12813,285,13256,"0,0214996982",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,35","14,76"
"low bq, many samples",UPN2_039,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),9485,242,9844,"0,0245835026",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,38","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),13200,245,13584,"0,0180359246",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,86","15,3"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),7636,153,7854,"0,0194805195",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,88","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_007,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),10575,177,10842,"0,0163254012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"28,03","16,33"
"low bq, low freq, many artifacts, many samples",UPN2_008,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),14952,277,15369,"0,0180232936",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,75","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_009,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),11620,189,11920,"0,0158557047",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,77",14
"low bq, low freq, many artifacts, many samples",UPN2_010,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),7475,125,7683,"0,0162696863",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,69","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_011,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),8391,118,8595,"0,0137289122",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,8","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),14965,314,15409,"0,0203777013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"28,02","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_056,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),2943,61,3032,"0,0201187335",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"28,06","16,1"
"low bq, low freq, many artifacts, many samples",UPN2_090,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),3567,53,3642,"0,0145524437",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"28,26","18,06"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),7870,159,8118,"0,019586105",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"28,21","16,35"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),7377,135,7581,"0,0178076771",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"28,14","16,26"
"low bq, many samples",UPN2_059,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),4698,133,4884,"0,0272317772",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,05","15,71"
"low bq, low freq, many artifacts, many samples",UPN2_012,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),4235,68,4360,"0,0155963303",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,86",14
"low bq, many samples",UPN2_040,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),3503,87,3622,"0,0240198785",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,35","16,39"
"low bq, low freq, many artifacts, many samples",UPN2_013,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),2085,28,2140,"0,0130841121",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,89",14
"low bq, low freq, many artifacts, many samples",UPN2_091,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),4077,52,4154,"0,0125180549",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"28,41","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_093,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),2369,31,2413,"0,0128470783",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"28,37","17,13"
"low bq, bad alignment, many samples",UPN2_061,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),2822,89,2939,"0,030282409",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"26,91","14,52"
"low bq, bad alignment, many samples",UPN2_062,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),2802,94,2925,"0,0321367521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"26,6","14,94"
"low bq, bad alignment, many samples",UPN2_063,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),2944,94,3087,"0,0304502753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"26,66","14,56"
"low bq, bad alignment, many samples",UPN2_064,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),4105,116,4269,"0,02717264",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"26,87","14,11"
"low bq, many samples",UPN2_065,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),1496,56,1572,"0,0356234097",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,26","14,23"
"low bq, many samples",UPN2_066,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),2482,87,2602,"0,0334358186",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,38","14,15"
"low bq, many samples",UPN2_067,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),2329,74,2430,"0,0304526749",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,27","14,47"
"low bq, bad alignment, many samples",UPN2_068,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),1920,74,2018,"0,0366699703",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"26,93","14,64"
"low bq, many samples",UPN2_069,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),3237,120,3391,"0,0353877912",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,07","14,62"
"low bq, bad alignment, many samples",UPN2_071,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),3837,132,4011,"0,0329094989",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"26,95","14,97"
"low bq, bad alignment, many samples",UPN2_072,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),2876,95,3006,"0,0316034597",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"26,96","14,61"
"low bq, many samples",UPN2_073,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),2787,92,2905,"0,0316695353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,03","14,65"
many samples,UPN2_074,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),1852,62,1925,"0,0322077922",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,27,"14,61"
"low bq, many samples",UPN2_075,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),5144,154,5357,"0,0287474333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,27","14,29"
"low bq, bad alignment, many samples",UPN2_076,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),2438,87,2548,"0,034144427",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"26,92","14,48"
"low bq, bad alignment, many samples",UPN2_078,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),3546,110,3701,"0,0297216968",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"26,88","14,24"
"low bq, many samples",UPN2_079,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),2169,60,2252,"0,026642984",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,31","14,43"
"low bq, many samples",UPN2_080,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),3302,89,3426,"0,0259778167",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,14","14,94"
"low bq, many samples",UPN2_081,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),5026,161,5246,"0,0306900496",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,08","14,49"
"low bq, many samples",UPN2_082,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),3248,86,3373,"0,0254965906",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,18","14,95"
"low bq, bad alignment, many samples",UPN2_083,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),3042,90,3172,"0,0283732661",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"26,97","14,29"
"low bq, bad alignment, many samples",UPN2_084,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),2455,74,2558,"0,0289288507",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"26,81","14,35"
"low bq, bad alignment, many samples",UPN2_085,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),2395,64,2488,"0,0257234727",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"26,87","14,11"
"low bq, bad alignment, many samples",UPN2_086,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),2250,69,2350,"0,0293617021",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"26,62","14,58"
"low bq, many samples",UPN2_087,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),3762,151,3966,"0,0380736258",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,09","15,19"
"low bq, many samples",UPN2_088,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),3201,97,3336,"0,0290767386",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"27,07","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_094,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),6395,90,6515,"0,0138142748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"28,33","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_095,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),5121,55,5210,"0,0105566219",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"28,03",14
"low bq, low freq, many artifacts, many samples",UPN2_096,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),5927,83,6047,"0,0137258145",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"28,3","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_097,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),6437,101,6588,"0,0153309047",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"28,21","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_098,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),4398,61,4476,"0,0136282395",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"28,38","16,66"
"low bq, low freq, many artifacts, many samples",UPN2_099,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),3032,37,3090,"0,01197411",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"28,24","15,54"
"low bq, low freq, many artifacts, many samples",UPN2_100,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),5273,73,5379,"0,0135712958",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"28,52","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_101,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),4142,60,4229,"0,0141877512",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"28,24","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_102,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),6112,92,6251,"0,0147176452",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"28,25","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_103,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),5371,85,5501,"0,015451736",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"28,11","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_104,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),6561,78,6678,"0,0116801438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"28,17","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_105,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),4502,69,4614,"0,0149544863",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"28,33","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_106,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),7619,88,7749,"0,011356304",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"28,32","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_107,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),9087,112,9270,"0,0120819849",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"28,34","15,34"
"low bq, low freq, many artifacts, many samples",UPN2_108,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),7946,89,8103,"0,0109835863",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"28,33","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_109,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),7093,105,7247,"0,014488754",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"28,15","15,79"
"low bq, low freq, many artifacts, many samples",UPN2_110,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),8056,113,8227,"0,0137352619",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"28,28","15,81"
"low bq, low freq, many artifacts",UPN2_111,2,25470577,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys299Asn/c.897A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|G),5881,80,6006,"0,0133200133",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,28,"15,84"
"inspected, homopolymer 5C, strandbias",UPN2_046,2,25470579,TC,T,frameshift_variant(HIGH||ggg/|p.Lys299fs/c.894delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|T),6220,68,6317,"0,0107646035",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,92",NA
"homopolymer 5C, strandbias",UPN2_090,2,25470579,TC,T,frameshift_variant(HIGH||ggg/|p.Lys299fs/c.894delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|T),1795,30,1834,"0,0163576881",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,61",NA
"inspected, many artifacts",UPN2_091,2,25470585,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp297Gly/c.889T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|C),2091,23,2124,"0,0108286252",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-9,97",Deleterious,"0,009",Damaging,"34,63","31,04"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,25470585,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp297Arg/c.889T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|T),4573,48,4656,"0,0103092784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,72",Deleterious,4,Damaging,"33,84","17,21"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,25470585,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp297Arg/c.889T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|T),5225,59,5335,"0,011059044",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,72",Deleterious,4,Damaging,"33,84","18,25"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,25470585,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp297Arg/c.889T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|T),5013,53,5105,"0,0103819785",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,72",Deleterious,4,Damaging,"33,68","20,45"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,25470585,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp297Arg/c.889T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|T),7604,99,7764,"0,0127511592",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,72",Deleterious,4,Damaging,"33,52","19,72"
"low bq, low freq, many artifacts, many samples",UPN2_056,2,25470585,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp297Arg/c.889T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|T),1507,26,1540,"0,0168831169",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,72",Deleterious,4,Damaging,"33,86","23,42"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,25470585,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp297Arg/c.889T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|T),4030,44,4093,"0,0107500611",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,72",Deleterious,4,Damaging,"33,73","17,95"
"low bq, low freq, many artifacts",UPN2_058,2,25470585,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp297Arg/c.889T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|T),3735,40,3806,"0,0105097215",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,72",Deleterious,4,Damaging,"33,69","19,52"
"inspected, many artifacts",UPN2_044,2,25470587,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val296Glu/c.887T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|T),1688,52,1748,"0,0297482838",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"33,59","29,58"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,25470587,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val296Glu/c.887T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|T),6218,70,6313,"0,0110882306",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"33,48","16,49"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,25470587,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val296Glu/c.887T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|T),8634,89,8799,"0,0101147858",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"33,47","18,06"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,25470587,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val296Glu/c.887T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|T),5060,53,5138,"0,0103152978",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"33,52","16,32"
"low bq, low freq, many artifacts, many samples",UPN2_010,2,25470587,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val296Glu/c.887T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|T),3821,45,3878,"0,0116039195",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"34,11","22,8"
"low bq, low freq, many artifacts",UPN2_055,2,25470587,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val296Glu/c.887T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|T),7641,87,7765,"0,0112041211",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,82",Deleterious,0,Damaging,"33,31","17,13"
"inspected, many artifacts",UPN2_002,2,25470602,C,T,missense_variant(MODERATE|MISSENSE|gGc/gAc|p.Gly291Asp/c.872G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|T),2344,33,2381,"0,0138597228",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,34",Deleterious,"0,025",Damaging,"34,6","32,97"
"low bq, low freq, many artifacts",UPN2_057,2,25470604,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe290Leu/c.870T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|T),4029,43,4100,"0,0104878049",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,43,Damaging,"34,42","26,09"
"low bq, low freq, many artifacts",UPN2_042,2,25470605,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe290Tyr/c.869T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|T),5128,57,5209,"0,0109425993",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,109,Tolerated,"33,92","19,3"
"inspected, many artifacts",UPN2_048,2,25470612,G,A,missense_variant(MODERATE|MISSENSE|Cgg/Tgg|p.Arg288Trp/c.862C>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|8|A),1587,23,1613,"0,0142591445",0,0,0,0,1,0,0,1,2,NO,NO,COSM2911825,large_intestine,3,NO,NO,NO,"8,24E-006",NO,NO,"-3,89",Deleterious,0,Damaging,"35,04","34,87"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25470967,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val265Gly/c.794T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|C),1377,22,1403,"0,0156806842",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,23",Neutral,27,Damaging,"28,99","16,73"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25470967,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val265Gly/c.794T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|C),2666,33,2706,"0,012195122",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,23",Neutral,27,Damaging,"28,78","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25470967,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val265Gly/c.794T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|C),2148,23,2176,"0,0105698529",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,23",Neutral,27,Damaging,"28,89","15,96"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25470967,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val265Gly/c.794T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|C),1818,28,1852,"0,0151187905",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,23",Neutral,27,Damaging,"29,2","17,64"
"low bq, low freq, many artifacts",UPN2_081,2,25470967,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val265Gly/c.794T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|C),2796,31,2835,"0,0109347443",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,23",Neutral,27,Damaging,"29,17","17,13"
"low bq, bad alignment, many samples",UPN2_001,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),10861,494,11424,"0,0432422969",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,9,Damaging,"25,73","15,03"
"low bq, bad alignment, many samples",UPN2_014,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),17382,1830,19325,"0,0946959897",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,9,Damaging,"25,82","15,06"
"low bq, bad alignment, many samples",UPN2_015,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),25817,3085,29047,"0,1062071815",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,9,Damaging,"25,94","14,98"
"low bq, many samples, no database",UPN2_016,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),12327,1192,13579,"0,0877826055",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"25,9","15,05"
"low bq, bad alignment, many samples",UPN2_017,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),8869,955,9889,"0,0965719486",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,9,Damaging,"25,87","15,09"
"low bq, bad alignment, many samples",UPN2_018,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),13715,1445,15249,"0,0947603122",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,9,Damaging,"25,89","14,99"
"low bq, bad alignment, many samples",UPN2_019,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),14834,1558,16462,"0,0946422063",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,9,Damaging,"25,78","14,97"
"low bq, bad alignment, many samples",UPN2_020,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),11378,1136,12578,"0,0903164255",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,9,Damaging,"25,85","15,01"
"low bq, many samples, no database",UPN2_021,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),15474,1515,17058,"0,0888146324",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"25,91","15,12"
"low bq, bad alignment, many samples",UPN2_002,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),14459,728,15252,"0,0477314451",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,9,Damaging,"25,72",15
"low bq, bad alignment, many samples",UPN2_003,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),2655,127,2796,"0,0454220315",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,9,Damaging,"25,7","14,63"
"low bq, many samples, no database",UPN2_022,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),18331,1923,20398,"0,0942739484",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"25,98","14,99"
"low bq, bad alignment, many samples",UPN2_023,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),19006,2078,21193,"0,0980512433",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,9,Damaging,"25,92","14,85"
"low bq, many samples, no database",UPN2_041,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),45576,4273,50149,"0,0852060859",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"26,13","15,59"
"low bq, bad alignment, many samples",UPN2_024,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),7233,768,8052,"0,0953800298",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,9,Damaging,"25,88","14,92"
"low bq, many samples, no database",UPN2_025,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),25925,2739,28808,"0,0950777562",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"25,92","15,03"
"low bq, many samples, no database",UPN2_026,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),21069,2327,23558,"0,0987774854",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"25,93","14,92"
"low bq, bad alignment, many samples",UPN2_004,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),4918,238,5172,"0,0460170147",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,9,Damaging,"25,63","14,62"
"low bq, many samples, no database",UPN2_027,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),22424,2571,25114,"0,1023731783",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"25,96","14,99"
"low bq, many samples, no database",UPN2_089,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),10236,1513,11791,"0,1283182088",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"27,4","18,71"
"low bq, many samples, no database",UPN2_042,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),37889,3662,41861,"0,0874799933",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"26,29","15,32"
"low bq, many samples, no database",UPN2_028,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),14000,1603,15703,"0,1020824046",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"25,88","14,88"
"low bq, many samples, no database",UPN2_043,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),17326,1651,19109,"0,086399079",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"26,36","15,49"
"low bq, many samples, no database",UPN2_044,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),8471,802,9340,"0,0858672377",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"26,35","15,32"
"low bq, bad alignment, many samples",UPN2_029,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),19815,2198,22159,"0,0991922018",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,9,Damaging,"25,96","15,14"
"low bq, many samples, no database",UPN2_030,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),21543,2239,23927,"0,0935762946",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"25,85","15,17"
"low bq, bad alignment, many samples",UPN2_031,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),15591,1629,17318,"0,0940639797",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,9,Damaging,"25,94","14,95"
"low bq, bad alignment, many samples",UPN2_005,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),3364,145,3537,"0,0409951937",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,9,Damaging,"25,63","15,36"
"low bq, many samples, no database",UPN2_045,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),28887,2769,31882,"0,086851515",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"26,29","15,28"
"low bq, many samples, no database",UPN2_032,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),6829,787,7668,"0,1026343245",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"26,06","15,13"
"low bq, many samples, no database",UPN2_046,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),29779,2833,32866,"0,086198503",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"26,26","15,48"
"low bq, many samples, no database",UPN2_033,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),15433,1619,17159,"0,0943528178",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"25,95","15,05"
"low bq, bad alignment, many samples",UPN2_034,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),5390,556,5985,"0,092898914",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,9,Damaging,"25,9","14,88"
"low bq, many samples, no database",UPN2_047,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),46200,4235,50695,"0,0835388105",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"26,35","15,4"
"low bq, many samples, no database",UPN2_048,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),41541,3754,45526,"0,0824583754",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"26,31","15,39"
"low bq, bad alignment, many samples",UPN2_035,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),20534,2115,22761,"0,0929221036",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,9,Damaging,"25,95","14,89"
"low bq, many samples, no database",UPN2_036,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),27299,2883,30358,"0,0949667304",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,26,"14,9"
"low bq, bad alignment, many samples",UPN2_006,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),9266,457,9754,"0,0468525733",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,9,Damaging,"25,82","15,02"
"low bq, many samples, no database",UPN2_049,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),28147,2659,30998,"0,0857797277",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"26,27","15,39"
"low bq, many samples, no database",UPN2_050,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),25690,2540,28434,"0,0893296757",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"26,29","15,34"
"low bq, many samples, no database",UPN2_037,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),31573,3432,35169,"0,0975859422",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"25,89","15,04"
"low bq, many samples, no database",UPN2_051,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),24188,2214,26574,"0,0833145179",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"26,3","15,44"
"low bq, many samples, no database",UPN2_052,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),23651,2358,26169,"0,0901066147",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"26,3","15,29"
"low bq, many samples, no database",UPN2_038,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),29423,3200,32793,"0,097581801",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"25,86","14,91"
"low bq, many samples, no database",UPN2_039,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),30217,3283,33702,"0,0974126165",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"25,88","15,06"
"low bq, bad alignment, many samples",UPN2_053,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),30653,3097,33959,"0,0911982096",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,9,Damaging,"26,31","15,34"
"low bq, many samples, no database",UPN2_054,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),17031,1709,18848,"0,0906727504",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"26,32","15,32"
"low bq, bad alignment, many samples",UPN2_007,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),32729,1556,34460,"0,0451538015",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,9,Damaging,"25,83","15,04"
"low bq, bad alignment, many samples",UPN2_008,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),49503,2435,52216,"0,0466332159",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,9,Damaging,"25,7","15,19"
"low bq, bad alignment, many samples",UPN2_009,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),41898,2076,44206,"0,0469619509",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,9,Damaging,"25,65","15,11"
"low bq, bad alignment, many samples",UPN2_010,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),26391,1311,27889,"0,0470077808",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,9,Damaging,"25,77","15,07"
"low bq, bad alignment, many samples",UPN2_011,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),26391,1284,27821,"0,0461521872",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,9,Damaging,"25,77","15,02"
"low bq, many samples, no database",UPN2_055,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),33328,3251,36817,"0,0883015998",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"26,34","15,42"
"low bq, bad alignment, many samples",UPN2_056,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),20413,1944,22531,"0,0862811238",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,9,Damaging,"26,34","15,41"
"low bq, many samples, no database",UPN2_090,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),8957,1581,10578,"0,1494611458",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"27,53","18,25"
"low bq, many samples, no database",UPN2_057,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),25664,2486,28304,"0,0878321085",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"26,33","15,27"
"low bq, bad alignment, many samples",UPN2_058,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),25363,2458,27975,"0,0878641644",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,9,Damaging,"26,37","15,25"
"low bq, many samples, no database",UPN2_059,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),868,251,1120,"0,2241071429",0,1,0,0,1,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"27,81","20,67"
"low bq, bad alignment, many samples",UPN2_012,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),16708,724,17530,"0,0413006275",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,9,Damaging,"25,74","15,04"
"low bq, many samples, no database",UPN2_060,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1700,506,2216,"0,2283393502",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"28,21","20,84"
"low bq, many samples, no database",UPN2_040,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),11963,1237,13263,"0,0932669833",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"25,91","15,02"
"low bq, bad alignment, many samples",UPN2_013,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),7701,409,8160,"0,050122549",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,9,Damaging,"25,78","14,96"
"low bq, many samples, no database",UPN2_091,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),12397,2110,14554,"0,1449773258",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"27,43","18,37"
"low bq, many samples",UPN2_092,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),7807,1421,9264,"0,1533894646",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,9,Damaging,"27,52","18,88"
"low bq, many samples, no database",UPN2_093,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),7052,1192,8278,"0,1439961343",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"27,46","18,16"
"low bq, many samples, no database",UPN2_061,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1353,403,1760,"0,2289772727",0,1,0,0,1,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"27,83","20,79"
"low bq, many samples, no database",UPN2_062,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),2378,716,3107,"0,2304473769",0,1,0,0,1,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"28,01","21,44"
"low bq, many samples, no database",UPN2_063,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),2133,610,2752,"0,2216569767",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"27,86","21,62"
"low bq, many samples, no database",UPN2_064,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1081,299,1385,"0,2158844765",0,1,0,0,1,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"27,86","21,33"
"low bq, many samples, no database",UPN2_065,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),488,117,610,"0,1918032787",0,1,0,0,1,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"27,71","20,97"
"low bq, many samples, no database",UPN2_066,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),151,48,205,"0,2341463415",0,1,0,0,1,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"28,25","21,48"
"low bq, many samples, no database",UPN2_067,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),295,82,381,"0,2152230971",0,1,0,0,1,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"28,32","21,46"
"low bq, many samples, no database",UPN2_068,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),768,237,1007,"0,2353525323",0,1,0,0,1,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"28,46","21,12"
"low bq, many samples, no database",UPN2_069,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1067,344,1421,"0,2420830401",0,1,0,0,1,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"28,21","21,01"
"low bq, many samples, no database",UPN2_070,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),731,233,974,"0,2392197125",0,1,0,0,1,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"28,39","21,48"
"low bq, many samples, no database",UPN2_071,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),4098,1161,5278,"0,2199696855",0,1,0,0,1,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"28,06","21,06"
"low bq, many samples, no database",UPN2_072,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),3267,929,4215,"0,2204033215",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"27,86","21,03"
"low bq, many samples, no database",UPN2_073,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1185,287,1481,"0,1937879811",0,1,0,0,1,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"27,67","20,6"
"low bq, many samples, no database",UPN2_074,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),466,130,599,"0,2170283806",0,1,0,0,1,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"28,42","20,76"
"low bq, many samples, no database",UPN2_075,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),2809,764,3577,"0,2135868046",0,1,0,0,1,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"28,03","21,27"
"low bq, many samples, no database",UPN2_076,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1378,373,1757,"0,2122936824",0,1,0,0,1,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"27,88","21,56"
"low bq, many samples, no database",UPN2_077,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),822,237,1063,"0,222953904",0,1,0,0,1,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"27,89","21,48"
"low bq, many samples, no database",UPN2_078,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1995,573,2576,"0,2224378882",0,1,0,0,1,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"28,1","21,24"
"low bq, many samples, no database",UPN2_079,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),868,225,1094,"0,2056672761",0,1,0,0,1,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"27,77","22,43"
"low bq, many samples, no database",UPN2_080,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),2275,604,2890,"0,2089965398",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"27,85","21,26"
"low bq, many samples, no database",UPN2_081,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),4336,1184,5538,"0,2137955941",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"27,99","20,88"
"low bq, many samples, no database",UPN2_082,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),706,192,902,"0,2128603104",0,1,0,0,1,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"27,74","21,51"
"low bq, many samples, no database",UPN2_083,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1551,456,2017,"0,2260783342",0,1,0,0,1,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"28,16","20,93"
"low bq, many samples, no database",UPN2_084,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1508,413,1933,"0,2136575272",0,1,0,0,1,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"27,88","21,79"
"low bq, many samples, no database",UPN2_085,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),618,170,793,"0,2143757881",0,1,0,0,1,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"27,78","20,92"
"low bq, many samples, no database",UPN2_086,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),275,63,338,"0,1863905325",0,1,0,0,1,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"27,38","21,63"
"low bq, many samples, no database",UPN2_087,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1118,316,1438,"0,2197496523",0,1,0,0,1,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"27,66","20,24"
"low bq, many samples, no database",UPN2_088,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),941,272,1224,"0,2222222222",0,1,0,0,1,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"28,26","21,76"
"low bq, many samples",UPN2_094,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),10579,1846,12471,"0,1480234143",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,9,Damaging,"27,44","18,62"
"low bq, many samples, no database",UPN2_095,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),12056,2239,14343,"0,1561040229",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"27,52","18,37"
"low bq, many samples, no database",UPN2_096,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),11221,1985,13270,"0,1495855313",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"27,39","18,38"
"low bq, many samples",UPN2_097,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),13083,2321,15454,"0,1501876537",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,9,Damaging,"27,43","18,31"
"low bq, many samples",UPN2_098,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),9731,1752,11526,"0,1520041645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,9,Damaging,"27,6","18,47"
"low bq, many samples, no database",UPN2_099,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),5427,1042,6490,"0,1605546995",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"27,51","18,38"
"low bq, many samples, no database",UPN2_100,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),9257,1484,10790,"0,1375347544",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"27,43","18,21"
"low bq, many samples",UPN2_101,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),8368,1564,9973,"0,1568234232",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,9,Damaging,"27,47","18,43"
"low bq, many samples, no database",UPN2_102,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),10393,1998,12429,"0,1607530775",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"27,46","18,04"
"low bq, many samples, no database",UPN2_103,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),9052,1774,10864,"0,1632916053",0,1,0,0,1,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"27,48","18,48"
"low bq, many samples, no database",UPN2_104,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),10894,1892,12824,"0,1475358702",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"27,32","18,52"
"low bq, many samples, no database",UPN2_105,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),7935,1430,9407,"0,1520144573",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"27,48","18,12"
"low bq, many samples",UPN2_106,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),15295,2661,18023,"0,1476446762",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,9,Damaging,"27,45","18,33"
"low bq, many samples, no database",UPN2_107,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),17699,3431,21218,"0,1617023282",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"27,5","18,22"
"low bq, many samples, no database",UPN2_108,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),14598,2551,17206,"0,1482622341",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"27,48","18,14"
"low bq, many samples, no database",UPN2_109,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),11445,1967,13472,"0,1460065321",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,009",Damaging,"27,42","18,19"
"low bq, many samples",UPN2_110,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),14358,2582,17006,"0,1518287663",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,9,Damaging,"27,42","18,44"
low bq,UPN2_111,2,25470973,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu263Ala/c.788A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),11830,2237,14122,"0,158405325",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,9,Damaging,"27,45","18,41"
"low freq, many artifacts",UPN2_084,2,25470980,T,C,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr261Ala/c.781A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|C),1853,25,1946,"0,0128468654",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,007",Damaging,"27,96","29,8"
"low bq, low freq, many artifacts, many samples",UPN2_089,2,25470980,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr261Pro/c.781A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),11731,126,11898,"0,0105900151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,4,Damaging,"29,15","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,25470980,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr261Pro/c.781A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),9244,101,9394,"0,0107515435",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,4,Damaging,"29,31","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,25470980,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr261Pro/c.781A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),31644,361,32212,"0,0112070036",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,4,Damaging,"29,27","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_090,2,25470980,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr261Pro/c.781A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),10508,119,10677,"0,0111454528",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,4,Damaging,"29,06","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,25470980,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr261Pro/c.781A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),28065,291,28526,"0,0102012199",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,4,Damaging,"29,18","14,36"
"low bq, many samples",UPN2_059,2,25470980,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr261Pro/c.781A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1088,34,1132,"0,0300353357",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,4,Damaging,"27,72",14
"low bq, many samples",UPN2_060,2,25470980,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr261Pro/c.781A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),2148,73,2238,"0,0326184093",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,4,Damaging,"27,91","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_091,2,25470980,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr261Pro/c.781A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),14494,155,14708,"0,0105384825",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,4,Damaging,"29,2","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_092,2,25470980,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr261Pro/c.781A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),9202,102,9337,"0,0109242797",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,4,Damaging,"29,06","14,85"
"low bq, many samples",UPN2_061,2,25470980,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr261Pro/c.781A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1700,64,1774,"0,0360766629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,4,Damaging,"27,95","15,28"
"low bq, many samples",UPN2_062,2,25470980,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr261Pro/c.781A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),3034,87,3134,"0,0277600511",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,4,Damaging,"27,89","14,31"
"low bq, many samples",UPN2_063,2,25470980,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr261Pro/c.781A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),2669,78,2775,"0,0281081081",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,4,Damaging,"28,08","14,92"
"low bq, many samples",UPN2_064,2,25470980,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr261Pro/c.781A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1347,49,1401,"0,0349750178",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,4,Damaging,"27,95","14,51"
"low bq, many samples",UPN2_068,2,25470980,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr261Pro/c.781A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),984,36,1026,"0,0350877193",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,4,Damaging,"28,27","14,19"
"low bq, many samples",UPN2_069,2,25470980,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr261Pro/c.781A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1381,50,1434,"0,0348675035",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,4,Damaging,"27,78","14,4"
"low bq, many samples",UPN2_070,2,25470980,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr261Pro/c.781A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),944,29,978,"0,0296523517",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,4,Damaging,"27,86","14,86"
"low bq, many samples",UPN2_071,2,25470980,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr261Pro/c.781A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),5156,158,5335,"0,0296157451",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,4,Damaging,"28,21","14,75"
"low bq, many samples",UPN2_072,2,25470980,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr261Pro/c.781A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),4156,106,4276,"0,0247895229",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,4,Damaging,"27,84","14,61"
"low bq, many samples",UPN2_073,2,25470980,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr261Pro/c.781A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1448,40,1494,"0,0267737617",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,4,Damaging,"27,91","14,18"
"low bq, many samples",UPN2_075,2,25470980,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr261Pro/c.781A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),3538,95,3643,"0,0260774087",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,4,Damaging,"27,89","14,42"
"low bq, many samples",UPN2_076,2,25470980,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr261Pro/c.781A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1741,50,1796,"0,0278396437",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,4,Damaging,"28,11","14,4"
"low bq, many samples",UPN2_077,2,25470980,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr261Pro/c.781A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1038,29,1072,"0,0270522388",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,4,Damaging,"27,51","14,48"
"low bq, many samples",UPN2_078,2,25470980,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr261Pro/c.781A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),2541,68,2616,"0,0259938838",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,4,Damaging,"27,99","14,81"
"low bq, many samples",UPN2_079,2,25470980,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr261Pro/c.781A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1069,32,1101,"0,0290644868",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,4,Damaging,"27,77","14,22"
"low bq, many samples",UPN2_080,2,25470980,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr261Pro/c.781A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),2824,76,2914,"0,0260809883",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,4,Damaging,"28,17","14,74"
"low bq, many samples",UPN2_081,2,25470980,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr261Pro/c.781A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),5442,128,5590,"0,0228980322",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,4,Damaging,"28,09","14,37"
"low bq, many samples",UPN2_082,2,25470980,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr261Pro/c.781A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),880,23,906,"0,0253863135",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,4,Damaging,"27,85","15,09"
"low bq, many samples",UPN2_083,2,25470980,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr261Pro/c.781A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1982,64,2060,"0,0310679612",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,4,Damaging,"27,97","14,11"
"low bq, many samples",UPN2_085,2,25470980,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr261Pro/c.781A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),775,28,803,"0,0348692403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,4,Damaging,"27,74","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_087,2,25470980,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr261Pro/c.781A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1417,28,1453,"0,0192704749",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,4,Damaging,"27,82","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_088,2,25470980,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr261Pro/c.781A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1209,26,1239,"0,0209846651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,4,Damaging,"27,88",14
"low bq, low freq, many artifacts, many samples",UPN2_094,2,25470980,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr261Pro/c.781A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),12418,140,12600,"0,0111111111",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,4,Damaging,"29,12","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_095,2,25470980,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr261Pro/c.781A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),14249,170,14474,"0,0117451983",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,4,Damaging,"29,11","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_096,2,25470980,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr261Pro/c.781A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),13143,134,13351,"0,0100367014",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,4,Damaging,"29,18","14,05"
"low bq, low freq, many artifacts, many samples",UPN2_099,2,25470980,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr261Pro/c.781A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),6446,73,6545,"0,0111535523",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,4,Damaging,"28,9","15,78"
"low bq, low freq, many artifacts, many samples",UPN2_101,2,25470980,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr261Pro/c.781A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),9882,110,10043,"0,0109529025",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,4,Damaging,"29,05","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_105,2,25470980,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr261Pro/c.781A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),9336,101,9480,"0,0106540084",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,4,Damaging,"29,15","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_107,2,25470980,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr261Pro/c.781A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),21066,224,21379,"0,0104775714",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,4,Damaging,"29,05","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_108,2,25470980,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr261Pro/c.781A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),17104,179,17333,"0,0103271217",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,4,Damaging,"29,26","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_110,2,25470980,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr261Pro/c.781A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),16873,207,17162,"0,0120615313",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,4,Damaging,"29,18","14,57"
"low bq, low freq, many artifacts",UPN2_111,2,25470980,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr261Pro/c.781A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),13965,177,14212,"0,012454264",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,4,Damaging,"29,12","14,9"
"low bq, low freq, many artifacts",UPN2_060,2,25470983,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr260Pro/c.778A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),2208,26,2245,"0,0115812918",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,5,Damaging,"30,59",14
"low freq, many artifacts",UPN2_080,2,25470985,GC,G,frameshift_variant(HIGH||gct/|p.Ala259fs/c.775delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),2872,31,2920,"0,0106164384",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,12",NA
"low bq, low freq, many artifacts, many samples",UPN2_001,2,25470988,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val258Glu/c.773T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),11323,123,11502,"0,0106937924",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,2,Damaging,"29,61","18,08"
"low bq, low freq, many artifacts, many samples",UPN2_014,2,25470988,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val258Glu/c.773T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),19220,198,19520,"0,0101434426",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,2,Damaging,"28,63","16,52"
"low bq, low freq, many artifacts, many samples",UPN2_020,2,25470988,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val258Glu/c.773T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),12478,139,12682,"0,0109604163",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,2,Damaging,"28,61","18,98"
"low bq, low freq, many artifacts, many samples",UPN2_041,2,25470988,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val258Glu/c.773T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),49517,848,50648,"0,0167430106",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,2,Damaging,"28,73","17,52"
"low bq, low freq, many artifacts, many samples",UPN2_026,2,25470988,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val258Glu/c.773T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),23380,239,23746,"0,010064853",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,2,Damaging,"28,7","17,97"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,25470988,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val258Glu/c.773T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),41485,588,42352,"0,0138836419",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,2,Damaging,"28,82","16,19"
"low bq, low freq, many artifacts, many samples",UPN2_028,2,25470988,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val258Glu/c.773T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),15594,160,15811,"0,010119537",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,2,Damaging,"28,57","17,96"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,25470988,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val258Glu/c.773T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),18932,292,19332,"0,01510449",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,2,Damaging,"28,89","17,44"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,25470988,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val258Glu/c.773T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),9225,130,9401,"0,0138283161",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,2,Damaging,"28,75","17,12"
"low bq, low freq, many artifacts, many samples",UPN2_029,2,25470988,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val258Glu/c.773T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),21980,226,22311,"0,0101295325",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,2,Damaging,"28,75","17,58"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,25470988,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val258Glu/c.773T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),31611,450,32261,"0,0139487307",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,2,Damaging,"28,85","16,7"
"low bq, low freq, many artifacts, many samples",UPN2_032,2,25470988,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val258Glu/c.773T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),7592,86,7728,"0,0111283644",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,2,Damaging,"28,57","18,43"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,25470988,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val258Glu/c.773T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),32575,444,33234,"0,0133598122",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,2,Damaging,"28,81","16,67"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,25470988,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val258Glu/c.773T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),50272,745,51261,"0,014533466",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,2,Damaging,"28,81","17,15"
"low bq, low freq, many artifacts, many samples",UPN2_048,2,25470988,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val258Glu/c.773T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),44977,710,46019,"0,01542841",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,2,Damaging,"28,78","16,98"
"low bq, low freq, many artifacts, many samples",UPN2_006,2,25470988,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val258Glu/c.773T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),9681,108,9831,"0,0109856576",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,2,Damaging,"29,5","19,74"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,25470988,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val258Glu/c.773T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),30611,474,31264,"0,0151612078",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,2,Damaging,"28,87","17,31"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,25470988,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val258Glu/c.773T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),28148,388,28695,"0,0135215194",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,2,Damaging,"28,97","16,61"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,25470988,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val258Glu/c.773T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),26307,389,26818,"0,0145051831",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,2,Damaging,"28,9","16,48"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,25470988,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val258Glu/c.773T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),25928,389,26461,"0,0147008805",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,2,Damaging,"28,93","16,78"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,25470988,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val258Glu/c.773T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),33624,499,34325,"0,0145375091",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,2,Damaging,"28,87","17,05"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,25470988,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val258Glu/c.773T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),18664,280,19059,"0,014691222",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,2,Damaging,"28,87","17,03"
"low bq, low freq, many artifacts, many samples",UPN2_007,2,25470988,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val258Glu/c.773T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),34277,352,34783,"0,0101198862",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,2,Damaging,"29,69","17,05"
"low bq, low freq, many artifacts, many samples",UPN2_011,2,25470988,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val258Glu/c.773T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),27636,295,28081,"0,0105053239",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,2,Damaging,"29,49","18,04"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,25470988,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val258Glu/c.773T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),36450,544,37196,"0,0146252285",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,2,Damaging,"28,82","16,99"
"low bq, low freq, many artifacts, many samples",UPN2_056,2,25470988,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val258Glu/c.773T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),22315,335,22778,"0,0147071736",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,2,Damaging,"28,88","16,33"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,25470988,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val258Glu/c.773T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),27960,450,28557,"0,0157579578",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,2,Damaging,"28,89","16,4"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,25470988,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val258Glu/c.773T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),27642,443,28246,"0,0156836366",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,2,Damaging,"28,91","17,35"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25470988,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val258Glu/c.773T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),2194,33,2245,"0,0146993318",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,2,Damaging,"28,65","16,36"
"low bq, low freq, many artifacts, many samples",UPN2_013,2,25470988,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val258Glu/c.773T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),8103,83,8231,"0,0100838294",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,2,Damaging,"29,43","19,51"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25470988,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val258Glu/c.773T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),1751,21,1780,"0,0117977528",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,2,Damaging,"28,93","17,29"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25470988,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val258Glu/c.773T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),2717,28,2777,"0,0100828232",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,2,Damaging,"28,68","17,39"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25470988,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val258Glu/c.773T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),5243,57,5347,"0,0106601833",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,2,Damaging,"28,55","16,28"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25470988,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val258Glu/c.773T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),4209,53,4294,"0,0123428039",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,2,Damaging,"28,46","16,04"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25470988,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val258Glu/c.773T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),3580,39,3651,"0,0106820049",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,2,Damaging,"28,88","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25470988,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val258Glu/c.773T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),5494,61,5598,"0,0108967488",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,2,Damaging,"28,52","17,34"
"low bq, low freq, many artifacts",UPN2_084,2,25470988,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val258Glu/c.773T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),1915,21,1949,"0,0107747563",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,2,Damaging,"28,61","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25470989,C,G,missense_variant(MODERATE|MISSENSE|Gtg/Ctg|p.Val258Leu/c.772G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),2216,30,2246,"0,0133570793",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,83,Tolerated,"29,74",14
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25470989,C,G,missense_variant(MODERATE|MISSENSE|Gtg/Ctg|p.Val258Leu/c.772G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),3103,33,3143,"0,0104995227",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,83,Tolerated,"29,86",14
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25470989,C,G,missense_variant(MODERATE|MISSENSE|Gtg/Ctg|p.Val258Leu/c.772G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1386,20,1406,"0,0142247511",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,83,Tolerated,"29,57",14
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25470989,C,G,missense_variant(MODERATE|MISSENSE|Gtg/Ctg|p.Val258Leu/c.772G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1412,20,1436,"0,0139275766",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,83,Tolerated,"29,98",16
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25470989,C,G,missense_variant(MODERATE|MISSENSE|Gtg/Ctg|p.Val258Leu/c.772G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),4236,52,4295,"0,0121071013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,83,Tolerated,"29,74",14
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25470989,C,G,missense_variant(MODERATE|MISSENSE|Gtg/Ctg|p.Val258Leu/c.772G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1775,22,1800,"0,0122222222",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,83,Tolerated,"30,19","16,73"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25470989,C,G,missense_variant(MODERATE|MISSENSE|Gtg/Ctg|p.Val258Leu/c.772G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),5531,60,5600,"0,0107142857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,83,Tolerated,"29,7","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25470989,C,G,missense_variant(MODERATE|MISSENSE|Gtg/Ctg|p.Val258Leu/c.772G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),2039,24,2068,"0,0116054159",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,83,Tolerated,"29,92","14,54"
"low bq, low freq, many artifacts",UPN2_084,2,25470989,C,G,missense_variant(MODERATE|MISSENSE|Gtg/Ctg|p.Val258Leu/c.772G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1927,20,1950,"0,0102564103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,83,Tolerated,"29,79",14
"low bq, low freq, many artifacts, many samples",UPN2_001,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),11336,117,11513,"0,0101624251",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"30,08","19,81"
"low bq, low freq, many artifacts, many samples",UPN2_002,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),15140,157,15386,"0,0102040816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,86","20,7"
"low bq, low freq, many artifacts, many samples",UPN2_041,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),49903,580,50766,"0,0114249695",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,9","20,08"
"low bq, low freq, many artifacts, many samples",UPN2_024,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),7992,85,8121,"0,0104666913",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,89","20,47"
"low bq, low freq, many artifacts, many samples",UPN2_004,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),5123,55,5205,"0,0105667627",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,96","19,29"
"low bq, low freq, many artifacts, many samples",UPN2_089,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),11736,140,11917,"0,0117479231",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,95","19,87"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),41594,521,42442,"0,0122755761",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,83","20,91"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),18967,258,19356,"0,0133292002",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,87","20,25"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),9268,112,9423,"0,0118858113",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,76","18,19"
"low bq, low freq, many artifacts, many samples",UPN2_005,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),3514,43,3578,"0,0120178871",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,94","20,51"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),31738,361,32324,"0,0111681723",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,88","18,65"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),32661,421,33311,"0,0126384678",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,75","19,82"
"low bq, low freq, many artifacts, many samples",UPN2_034,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),5932,66,6036,"0,0109343936",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,85","23,36"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),50380,610,51354,"0,0118783347",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,93","20,35"
"low bq, low freq, many artifacts, many samples",UPN2_048,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),45307,494,46113,"0,0107128142",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,97","19,76"
"low bq, low freq, many artifacts, many samples",UPN2_006,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),9693,109,9845,"0,01107161",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,93","20,24"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),30820,315,31339,"0,0100513737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,84","19,38"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),28264,304,28764,"0,0105687665",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,84","19,18"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),26410,302,26873,"0,0112380456",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,97","20,72"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),26061,279,26523,"0,010519172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,79","19,23"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),33680,444,34412,"0,0129024759",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,71","19,04"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),18742,225,19096,"0,0117825723",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,77","19,04"
"low bq, low freq, many artifacts, many samples",UPN2_007,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),34284,378,34821,"0,0108555182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"30,16","21,21"
"low bq, low freq, many artifacts, many samples",UPN2_011,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),27604,293,28073,"0,0104370748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,30,"20,87"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),36609,422,37280,"0,0113197425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,78","19,55"
"low bq, low freq, many artifacts, many samples",UPN2_056,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),22395,281,22819,"0,0123142995",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,89","20,01"
"low bq, low freq, many artifacts, many samples",UPN2_090,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),10528,135,10712,"0,0126026886",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,79","19,61"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),28103,317,28617,"0,0110773317",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,76","19,48"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),27715,322,28221,"0,011409943",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,99","19,05"
"low bq, many samples",UPN2_059,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1099,30,1135,"0,0264317181",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,04","17,07"
"low bq, many samples",UPN2_060,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),2166,73,2253,"0,0324012428",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"28,4","16,03"
"low bq, low freq, many artifacts, many samples",UPN2_091,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),14452,210,14720,"0,0142663043",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,93","20,94"
"low bq, low freq, many artifacts, many samples",UPN2_092,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),9202,119,9346,"0,0127327199",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,9","22,36"
"low bq, low freq, many artifacts, many samples",UPN2_093,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),8233,92,8345,"0,0110245656",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"30,03","20,42"
"low bq, many samples",UPN2_061,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1726,48,1784,"0,0269058296",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"28,46","16,21"
"low bq, many samples",UPN2_062,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),3030,91,3144,"0,0289440204",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"28,22","16,24"
"low bq, many samples",UPN2_063,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),2672,84,2782,"0,030194105",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"28,34","17,31"
"low bq, many samples",UPN2_064,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1367,33,1409,"0,0234208659",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"28,71","18,06"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1002,21,1028,"0,0204280156",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"28,6","15,48"
"low bq, many samples",UPN2_069,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1397,39,1438,"0,0271210014",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"28,5","19,28"
"low bq, many samples",UPN2_070,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),943,32,982,"0,032586558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"28,26","14,22"
"low bq, many samples",UPN2_071,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),5170,163,5352,"0,0304559043",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"28,52","16,79"
"low bq, many samples",UPN2_072,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),4139,127,4299,"0,0295417539",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"28,36","16,16"
"low bq, many samples",UPN2_073,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1454,33,1495,"0,0220735786",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"28,56","17,88"
"low bq, many samples",UPN2_075,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),3556,89,3663,"0,0242970243",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"28,68","16,44"
"low bq, many samples",UPN2_076,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1744,58,1804,"0,0321507761",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"28,88","15,62"
"low bq, many samples",UPN2_077,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1030,42,1074,"0,0391061453",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"28,47","15,26"
"low bq, many samples",UPN2_078,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),2538,81,2630,"0,0307984791",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"28,42","18,86"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1085,21,1111,"0,0189018902",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"28,67","16,1"
"low bq, many samples",UPN2_080,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),2839,75,2927,"0,0256235053",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"28,58","16,64"
"low bq, many samples",UPN2_081,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),5407,166,5610,"0,0295900178",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"28,58","17,78"
"low bq, many samples",UPN2_083,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),2008,51,2071,"0,0246257846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"28,29",15
"low bq, many samples",UPN2_084,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1881,62,1951,"0,0317785751",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"28,65","15,44"
"low bq, many samples",UPN2_087,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1403,39,1461,"0,0266940452",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"28,6","15,08"
"low bq, many samples",UPN2_088,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1205,32,1243,"0,0257441673",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"28,75",14
"low bq, low freq, many artifacts, many samples",UPN2_094,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),12430,140,12620,"0,0110935024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,94","18,99"
"low bq, low freq, many artifacts, many samples",UPN2_095,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),14290,171,14503,"0,011790664",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,89","19,43"
"low bq, low freq, many artifacts, many samples",UPN2_096,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),13184,139,13373,"0,0103940776",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,30,"18,22"
"low bq, low freq, many artifacts, many samples",UPN2_097,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),15382,171,15600,"0,0109615385",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,96","18,38"
"low bq, low freq, many artifacts, many samples",UPN2_098,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),11528,129,11688,"0,011036961",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,94","20,13"
"low bq, low freq, many artifacts, many samples",UPN2_099,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),6444,83,6557,"0,0126582278",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,73","18,72"
"low bq, low freq, many artifacts, many samples",UPN2_100,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),10732,116,10887,"0,0106549095",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"30,2","19,07"
"low bq, low freq, many artifacts, many samples",UPN2_101,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),9901,114,10060,"0,011332008",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,9","18,59"
"low bq, low freq, many artifacts, many samples",UPN2_102,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),12373,140,12558,"0,011148272",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,76","18,61"
"low bq, low freq, many artifacts, many samples",UPN2_103,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),10789,133,10973,"0,0121206598",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,79","19,57"
"low bq, low freq, many artifacts, many samples",UPN2_104,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),12778,153,12972,"0,0117946346",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,89","19,27"
"low bq, low freq, many artifacts, many samples",UPN2_105,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),9339,127,9501,"0,013367014",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,76","19,3"
"low bq, low freq, many artifacts, many samples",UPN2_106,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),17931,225,18234,"0,0123395854",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,99","19,4"
"low bq, low freq, many artifacts, many samples",UPN2_107,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),21058,280,21422,"0,013070675",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,77","20,59"
"low bq, low freq, many artifacts, many samples",UPN2_108,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),17103,207,17363,"0,0119219029",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"30,01","19,97"
"low bq, low freq, many artifacts, many samples",UPN2_109,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),13408,146,13614,"0,0107242544",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,77","17,63"
"low bq, low freq, many artifacts, many samples",UPN2_110,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),16894,232,17205,"0,0134844522",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,89","20,19"
"low bq, low freq, many artifacts",UPN2_111,2,25470992,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr257Pro/c.769A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),14004,178,14244,"0,0124964898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,28,Damaging,"29,79","18,97"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25470998,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser255Ala/c.763T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|C),2208,28,2257,"0,0124058485",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,2",Neutral,6,Damaging,"30,65","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25470998,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser255Ala/c.763T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|C),3085,37,3150,"0,0117460317",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,2",Neutral,6,Damaging,"30,25","15,57"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25470998,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser255Ala/c.763T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|C),2725,40,2786,"0,0143575018",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,2",Neutral,6,Damaging,"30,59","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25470998,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser255Ala/c.763T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|C),2568,37,2631,"0,0140630939",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,2",Neutral,6,Damaging,"30,54","15,54"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25470998,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser255Ala/c.763T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|C),2036,23,2072,"0,0111003861",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,2",Neutral,6,Damaging,"30,23","14,3"
"low bq, low freq, many artifacts",UPN2_084,2,25470998,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser255Ala/c.763T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|C),1909,25,1951,"0,0128139416",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,2",Neutral,6,Damaging,"30,13","15,6"
"low freq, many artifacts",UPN2_061,2,25470998,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser255Pro/c.763T>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1737,22,1784,"0,0123318386",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,01",Neutral,"0,003",Damaging,"30,65","33,45"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25471006,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp252Ala/c.755A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),2220,27,2257,"0,0119627825",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,5,Damaging,"28,78","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25471006,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp252Ala/c.755A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1753,28,1784,"0,0156950673",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,5,Damaging,"29,23","15,57"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25471006,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp252Ala/c.755A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),3084,52,3151,"0,0165026976",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,5,Damaging,"28,53","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25471006,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp252Ala/c.755A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),2729,46,2786,"0,0165111271",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,5,Damaging,"28,98","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25471006,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp252Ala/c.755A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1387,26,1413,"0,0184005662",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,5,Damaging,"28,88","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25471006,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp252Ala/c.755A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),5262,75,5360,"0,0139925373",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,5,Damaging,"29,1","14,09"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25471006,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp252Ala/c.755A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),4216,66,4300,"0,0153488372",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,5,Damaging,"28,87","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25471006,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp252Ala/c.755A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),3599,46,3661,"0,012564873",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,5,Damaging,"28,86",14
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25471006,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp252Ala/c.755A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1775,25,1806,"0,0138427464",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,5,Damaging,"28,95","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25471006,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp252Ala/c.755A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),2579,42,2630,"0,0159695817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,5,Damaging,"29,05","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25471006,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp252Ala/c.755A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),2881,41,2936,"0,0139645777",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,5,Damaging,"28,89","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25471006,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp252Ala/c.755A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),5520,73,5613,"0,0130055229",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,5,Damaging,"28,98","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25471006,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp252Ala/c.755A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),2036,30,2072,"0,0144787645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,5,Damaging,29,"14,23"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25471006,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp252Ala/c.755A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1922,23,1950,"0,0117948718",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,5,Damaging,"29,16","14,3"
"low bq, low freq, many artifacts",UPN2_087,2,25471006,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp252Ala/c.755A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1432,22,1463,"0,015037594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,5,Damaging,"28,66",14
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25471010,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr251Pro/c.751A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),2218,27,2256,"0,0119680851",0,0,0,0,1,0,0,0,1,0,NO,NO,NO,O,NO,rs139388008,NO,NO,NO,NO,"-1,52",Neutral,"0,01",Damaging,"29,89","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25471010,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr251Pro/c.751A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1756,20,1784,"0,0112107623",0,0,0,0,1,0,0,0,1,0,NO,NO,NO,O,NO,rs139388008,NO,NO,NO,NO,"-1,52",Neutral,"0,01",Damaging,"30,31","18,55"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25471010,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr251Pro/c.751A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),3089,33,3150,"0,0104761905",0,0,0,0,1,0,0,0,1,0,NO,NO,NO,O,NO,rs139388008,NO,NO,NO,NO,"-1,52",Neutral,"0,01",Damaging,"29,67","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25471010,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr251Pro/c.751A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),2743,31,2786,"0,0111270639",0,0,0,0,1,0,0,0,1,0,NO,NO,NO,O,NO,rs139388008,NO,NO,NO,NO,"-1,52",Neutral,"0,01",Damaging,"30,05","16,1"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25471010,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr251Pro/c.751A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),4221,48,4296,"0,0111731844",0,0,0,0,1,0,0,0,1,0,NO,NO,NO,O,NO,rs139388008,NO,NO,NO,NO,"-1,52",Neutral,"0,01",Damaging,"29,89","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25471010,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr251Pro/c.751A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),3606,37,3661,"0,0101065283",0,0,0,0,1,0,0,0,1,0,NO,NO,NO,O,NO,rs139388008,NO,NO,NO,NO,"-1,52",Neutral,"0,01",Damaging,"30,14","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25471010,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr251Pro/c.751A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),2574,29,2630,"0,011026616",0,0,0,0,1,0,0,0,1,0,NO,NO,NO,O,NO,rs139388008,NO,NO,NO,NO,"-1,52",Neutral,"0,01",Damaging,"30,22",14
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25471010,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr251Pro/c.751A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),2874,35,2935,"0,0119250426",0,0,0,0,1,0,0,0,1,0,NO,NO,NO,O,NO,rs139388008,NO,NO,NO,NO,"-1,52",Neutral,"0,01",Damaging,"30,09","14,89"
"low bq, low freq, many artifacts",UPN2_083,2,25471010,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr251Pro/c.751A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),2039,25,2073,"0,0120598167",0,0,0,0,1,0,0,0,1,0,NO,NO,NO,O,NO,rs139388008,NO,NO,NO,NO,"-1,52",Neutral,"0,01",Damaging,"29,89",14
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25471015,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln249Pro/c.746A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),2214,27,2256,"0,0119680851",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,151,Tolerated,"29,23","16,33"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25471015,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln249Pro/c.746A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1754,21,1784,"0,0117713004",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,151,Tolerated,"29,24",14
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25471015,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln249Pro/c.746A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),2740,32,2783,"0,011498383",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,151,Tolerated,"29,56","15,56"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25471015,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln249Pro/c.746A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),2590,30,2631,"0,0114025086",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,151,Tolerated,"29,4","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25471015,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln249Pro/c.746A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),2884,31,2931,"0,010576595",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,151,Tolerated,"29,6",14
"low bq, low freq, many artifacts",UPN2_081,2,25471015,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln249Pro/c.746A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),5525,57,5613,"0,0101549973",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,151,Tolerated,"29,63","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,25471021,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val247Gly/c.740T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|C),1106,24,1136,"0,0211267606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,2,Damaging,"27,66","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25471021,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val247Gly/c.740T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|C),2186,44,2253,"0,0195295162",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,2,Damaging,"27,54","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25471021,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val247Gly/c.740T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|C),1738,26,1781,"0,0145985401",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,2,Damaging,"27,61","14,27"
"low bq, many samples",UPN2_062,2,25471021,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val247Gly/c.740T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|C),3042,75,3144,"0,0238549618",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,2,Damaging,"27,36","14,72"
"low bq, many samples",UPN2_063,2,25471021,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val247Gly/c.740T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|C),2687,63,2782,"0,0226455787",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,2,Damaging,"27,72","14,63"
"low bq, many samples",UPN2_064,2,25471021,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val247Gly/c.740T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|C),1362,36,1408,"0,0255681818",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,2,Damaging,"27,58","15,28"
"low bq, many samples",UPN2_068,2,25471021,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val247Gly/c.740T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|C),979,23,1026,"0,022417154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,2,Damaging,"28,09",14
"low bq, many samples",UPN2_069,2,25471021,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val247Gly/c.740T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|C),1388,38,1437,"0,0264439805",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,2,Damaging,"27,88","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25471021,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val247Gly/c.740T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|C),5204,109,5353,"0,0203624136",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,2,Damaging,"27,99","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25471021,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val247Gly/c.740T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|C),4185,74,4294,"0,0172333489",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,2,Damaging,"27,42","14,19"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25471021,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val247Gly/c.740T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|C),1453,30,1498,"0,0200267023",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,2,Damaging,"27,89","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25471021,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val247Gly/c.740T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|C),3552,74,3660,"0,0202185792",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,2,Damaging,"28,1","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25471021,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val247Gly/c.740T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|C),1756,30,1802,"0,0166481687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,2,Damaging,"27,82",14
"low bq, many samples",UPN2_077,2,25471021,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val247Gly/c.740T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|C),1039,24,1072,"0,0223880597",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,2,Damaging,"27,63","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25471021,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val247Gly/c.740T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|C),2508,48,2628,"0,0182648402",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,2,Damaging,"27,88",14
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25471021,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val247Gly/c.740T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|C),1077,22,1109,"0,0198376916",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,2,Damaging,"27,89","16,86"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25471021,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val247Gly/c.740T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|C),2836,63,2924,"0,0215458276",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,2,Damaging,"27,72","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25471021,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val247Gly/c.740T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|C),5466,102,5599,"0,0182175388",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,2,Damaging,"27,66","14,32"
"low bq, many samples",UPN2_083,2,25471021,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val247Gly/c.740T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|C),1995,47,2066,"0,022749274",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,2,Damaging,"28,01","14,15"
"low bq, many samples",UPN2_084,2,25471021,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val247Gly/c.740T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|C),1877,48,1946,"0,0246659815",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,2,Damaging,"27,57","14,52"
"low bq, many samples",UPN2_085,2,25471021,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val247Gly/c.740T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|C),786,20,809,"0,0247218789",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,2,Damaging,"28,07",16
low bq,UPN2_087,2,25471021,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val247Gly/c.740T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|C),1414,33,1461,"0,022587269",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,2,Damaging,"27,87","14,21"
"low freq, many artifacts",UPN2_078,2,25471021,A,G,missense_variant(MODERATE|MISSENSE|gTg/gCg|p.Val247Ala/c.740T>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),2508,58,2628,"0,0220700152",0,0,0,0,0,1,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,4",Neutral,"0,127",Tolerated,"27,88","32,02"
"low freq, many artifacts",UPN2_072,2,25471025,C,T,missense_variant(MODERATE|MISSENSE|Gct/Act|p.Ala246Thr/c.736G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),4238,47,4292,"0,0109506058",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,173",Tolerated,"31,89","32,72"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_090,2,25471034,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser243Arg/c.727A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),5331,56,5423,"0,0103263876",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,14",Neutral,65,Tolerated,"26,24","14,95"
"low bq, bad alignment, many samples",UPN2_060,2,25471034,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser243Arg/c.727A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1080,33,1121,"0,0294380018",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,14",Neutral,65,Tolerated,"23,8","14,42"
"low bq, bad alignment, many samples",UPN2_061,2,25471034,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser243Arg/c.727A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),852,25,883,"0,0283125708",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,14",Neutral,65,Tolerated,"24,13","14,28"
"low bq, bad alignment, many samples",UPN2_062,2,25471034,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser243Arg/c.727A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1496,61,1566,"0,0389527458",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,14",Neutral,65,Tolerated,"22,77","14,51"
"low bq, bad alignment, many samples",UPN2_063,2,25471034,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser243Arg/c.727A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1340,41,1385,"0,0296028881",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,14",Neutral,65,Tolerated,"23,64","14,32"
"low bq, bad alignment, many samples",UPN2_064,2,25471034,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser243Arg/c.727A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),678,22,703,"0,0312944523",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,14",Neutral,65,Tolerated,"23,33",14
"low bq, bad alignment, many samples",UPN2_069,2,25471034,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser243Arg/c.727A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),684,24,713,"0,0336605891",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,14",Neutral,65,Tolerated,"23,42","14,75"
"low bq, bad alignment, many samples",UPN2_071,2,25471034,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser243Arg/c.727A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),2566,87,2664,"0,0326576577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,14",Neutral,65,Tolerated,"23,3","14,53"
"low bq, bad alignment, many samples",UPN2_072,2,25471034,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser243Arg/c.727A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),2063,68,2135,"0,0318501171",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,14",Neutral,65,Tolerated,"23,66","14,53"
"low bq, bad alignment, many samples",UPN2_073,2,25471034,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser243Arg/c.727A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),714,25,744,"0,0336021505",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,14",Neutral,65,Tolerated,24,"14,72"
"low bq, bad alignment, many samples",UPN2_075,2,25471034,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser243Arg/c.727A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1755,53,1818,"0,0291529153",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,14",Neutral,65,Tolerated,"24,1","14,26"
"low bq, bad alignment, many samples",UPN2_076,2,25471034,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser243Arg/c.727A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),856,32,897,"0,0356744705",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,14",Neutral,65,Tolerated,"24,18","14,41"
"low bq, bad alignment, many samples",UPN2_078,2,25471034,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser243Arg/c.727A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1265,44,1314,"0,0334855403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,14",Neutral,65,Tolerated,"23,26","14,32"
"low bq, bad alignment, many samples",UPN2_080,2,25471034,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser243Arg/c.727A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1410,38,1456,"0,0260989011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,14",Neutral,65,Tolerated,"24,09","14,34"
"low bq, bad alignment, many samples",UPN2_081,2,25471034,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser243Arg/c.727A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),2689,82,2787,"0,0294223179",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,14",Neutral,65,Tolerated,"24,03","14,89"
"low bq, bad alignment, many samples",UPN2_083,2,25471034,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser243Arg/c.727A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),987,40,1035,"0,038647343",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,14",Neutral,65,Tolerated,"23,87","14,5"
"low bq, bad alignment, many samples",UPN2_084,2,25471034,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser243Arg/c.727A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),932,29,965,"0,0300518135",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,14",Neutral,65,Tolerated,"24,04",15
"low bq, bad alignment, many samples",UPN2_087,2,25471034,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser243Arg/c.727A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),701,23,727,"0,0316368638",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,14",Neutral,65,Tolerated,"24,1","15,09"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_094,2,25471034,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser243Arg/c.727A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),6332,70,6436,"0,0108763207",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,14",Neutral,65,Tolerated,"26,27","14,41"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_095,2,25471034,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser243Arg/c.727A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),7285,81,7401,"0,010944467",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,14",Neutral,65,Tolerated,"26,15","14,78"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_099,2,25471034,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser243Arg/c.727A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),3295,41,3352,"0,0122315036",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,14",Neutral,65,Tolerated,"25,87","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_100,2,25471034,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser243Arg/c.727A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),5430,60,5516,"0,0108774474",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,14",Neutral,65,Tolerated,"27,06","15,55"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_102,2,25471034,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser243Arg/c.727A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),6316,75,6418,"0,0116858835",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,14",Neutral,65,Tolerated,"25,91","15,16"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_105,2,25471034,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser243Arg/c.727A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),4735,55,4812,"0,0114297589",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,14",Neutral,65,Tolerated,"26,15","14,13"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_106,2,25471034,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser243Arg/c.727A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),9098,101,9232,"0,010940208",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,14",Neutral,65,Tolerated,"26,58","14,57"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_107,2,25471034,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser243Arg/c.727A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),10752,115,10903,"0,0105475557",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,14",Neutral,65,Tolerated,"25,92","14,71"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_109,2,25471034,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser243Arg/c.727A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),6806,82,6931,"0,0118309046",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,14",Neutral,65,Tolerated,"26,18","14,94"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_110,2,25471034,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser243Arg/c.727A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),8634,111,8795,"0,0126208073",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,14",Neutral,65,Tolerated,"26,03","14,87"
"low bq, bad alignment, low freq, many artifacts",UPN2_111,2,25471034,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser243Arg/c.727A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),7182,82,7293,"0,0112436583",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,14",Neutral,65,Tolerated,"25,99",14
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25471039,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu241Ala/c.722A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1535,24,1566,"0,0153256705",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,96",Neutral,59,Tolerated,"29,49","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25471039,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu241Ala/c.722A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),2624,30,2664,"0,0112612613",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,96",Neutral,59,Tolerated,"30,05","16,87"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,25471045,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val239Glu/c.716T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),25533,264,25896,"0,0101946247",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,411,Tolerated,"34,29","18,65"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,25471045,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val239Glu/c.716T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),18552,194,18801,"0,0103186001",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,411,Tolerated,"34,25","19,37"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,25471045,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val239Glu/c.716T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),14270,146,14459,"0,0100975171",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,411,Tolerated,"34,27","18,06"
"low bq, low freq, many artifacts",UPN2_058,2,25471045,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val239Glu/c.716T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),14036,145,14211,"0,0102033636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,411,Tolerated,"34,21","20,38"
"inspected, low freq, neutral effect",UPN2_065,2,25471069,T,C,missense_variant(MODERATE|MISSENSE|cAg/cGg|p.Gln231Arg/c.692A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|C),310,22,337,"0,0652818991",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,326,Tolerated,"33,8",32
many samples,UPN2_059,2,25471069,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln231Pro/c.692A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),561,31,605,"0,0512396694",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,76",Neutral,329,Tolerated,"33,73","31,42"
"inspected, strandbias, bad alignment",UPN2_061,2,25471069,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln231Pro/c.692A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),883,32,918,"0,0348583878",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,76",Neutral,"0,329",Tolerated,"33,53","32,12"
many samples,UPN2_064,2,25471069,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln231Pro/c.692A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),704,38,743,"0,0511440108",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,76",Neutral,329,Tolerated,"33,76","30,76"
"inspected, strandbias, bad alignment",UPN2_066,2,25471069,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln231Pro/c.692A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),104,36,140,"0,2571428571",0,1,0,0,1,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,76",Neutral,"0,329",Tolerated,"33,69","31,08"
many samples,UPN2_076,2,25471069,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln231Pro/c.692A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),898,22,925,"0,0237837838",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,76",Neutral,329,Tolerated,"33,5","31,18"
"inspected, low freq, neutral effect",UPN2_083,2,25471069,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln231Pro/c.692A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|G),1035,68,1107,"0,0614272809",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,76",Neutral,329,Tolerated,"33,17","31,15"
"low bq, low freq, many artifacts",UPN2_041,2,25471081,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val227Glu/c.680T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|7|T),26240,306,26664,"0,0114761476",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,2,Damaging,"34,22","23,54"
"low freq, many artifacts",UPN2_043,2,25497815,T,C,missense_variant(MODERATE|MISSENSE|Agg/Ggg|p.Arg212Gly/c.634A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|C),2214,25,2265,"0,0110375276",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,"0,008",Damaging,"34,59","35,4"
"low freq, many artifacts",UPN2_029,2,25497815,T,C,missense_variant(MODERATE|MISSENSE|Agg/Ggg|p.Arg212Gly/c.634A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|C),2201,24,2236,"0,0107334526",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,"0,008",Damaging,"35,09","35,08"
"low freq, many artifacts, many samples",UPN2_010,2,25497815,T,C,missense_variant(MODERATE|MISSENSE|Agg/Ggg|p.Arg212Gly/c.634A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|C),1755,22,1787,"0,012311136",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,8,Damaging,"34,98",36
"low freq, many artifacts",UPN2_057,2,25497815,T,C,missense_variant(MODERATE|MISSENSE|Agg/Ggg|p.Arg212Gly/c.634A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|C),2561,30,2624,"0,0114329268",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,"0,008",Damaging,"34,61",36
"low freq, many artifacts, many samples",UPN2_071,2,25497815,T,C,missense_variant(MODERATE|MISSENSE|Agg/Ggg|p.Arg212Gly/c.634A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|C),1423,21,1449,"0,0144927536",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,8,Damaging,"34,58","35,43"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,25497816,T,A,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys211Asn/c.633A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|A),2218,25,2264,"0,0110424028",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,2,Damaging,"34,23","17,8"
"low bq, low freq, many artifacts, many samples",UPN2_048,2,25497816,T,A,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys211Asn/c.633A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|A),2167,25,2198,"0,0113739763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,2,Damaging,"34,39","15,76"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,25497816,T,A,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys211Asn/c.633A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|A),2335,31,2389,"0,0129761406",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,2,Damaging,"34,23","18,84"
"low bq, low freq, many artifacts",UPN2_051,2,25497816,T,A,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys211Asn/c.633A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|A),2156,24,2196,"0,0109289617",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,2,Damaging,"34,27","17,46"
"low bq, low freq, many artifacts",UPN2_051,2,25497817,T,A,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys211Ile/c.632A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|A),2165,24,2196,"0,0109289617",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,1,Damaging,"34,89","15,21"
"low freq, many artifacts",UPN2_041,2,25497818,T,C,missense_variant(MODERATE|MISSENSE|Aaa/Gaa|p.Lys211Glu/c.631A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|C),1283,22,1317,"0,0167046317",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,rs80021709,NO,NO,NO,NO,"-0,41",Neutral,"0,05",Damaging,"34,7","35,14"
"Inspected, not in 2nd Illumina",UPN2_083,2,25497826,G,A,missense_variant(MODERATE|MISSENSE|gCa/gTa|p.Ala208Val/c.623C>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|A),595,23,619,"0,0371567044",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,38",Neutral,"0,003",Damaging,"34,68","33,39"
inspected,UPN2_056,2,25497835,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu205Val/c.614A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|A),1099,41,1145,"0,0358078603",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,"0,001",Damaging,"34,51","31,76"
"low freq, many artifacts",UPN2_041,2,25497838,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp204Gly/c.611A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|C),1287,22,1314,"0,0167427702",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,82",Neutral,"0,001",Damaging,"34,53","34,45"
"inspected, many artifacts",UPN2_092,2,25497839,C,T,missense_variant(MODERATE|MISSENSE|Gac/Aac|p.Asp204Asn/c.610G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|T),807,25,833,"0,0300120048",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,"0,001",Damaging,"35,19","35,84"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,25497844,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys202Met/c.605A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|A),2224,28,2260,"0,0123893805",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,4,Damaging,"33,72","18,18"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,25497844,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys202Met/c.605A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|A),2157,26,2189,"0,0118775697",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,4,Damaging,"33,88","17,08"
"low freq, many artifacts",UPN2_007,2,25497844,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys202Met/c.605A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|A),2341,35,2383,"0,0146873689",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,"0,004",Damaging,"34,26","31,06"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,25497845,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys202*/c.604A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|A),2219,35,2260,"0,0154867257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,08","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,25497845,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys202*/c.604A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|A),3466,37,3513,"0,0105323086",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,23","19,24"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,25497845,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys202*/c.604A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|A),3719,40,3774,"0,0105988341",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,16","18,6"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,25497845,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys202*/c.604A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|A),2345,33,2386,"0,013830679",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,04","19,21"
"low bq, low freq, many artifacts",UPN2_053,2,25497845,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys202*/c.604A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|A),3087,37,3142,"0,0117759389",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,31","19,7"
"low freq, many artifacts",UPN2_048,2,25497845,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys202Glu/c.604A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|C),2150,36,2199,"0,0163710778",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,0,Neutral,"0,019",Damaging,"33,29","34,83"
"low freq, many artifacts",UPN2_047,2,25497848,G,A,missense_variant(MODERATE|MISSENSE|Cgc/Tgc|p.Arg201Cys/c.601C>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|A),7482,84,7581,"0,0110803324",0,0,0,0,1,1,0,1,3,NO,NO,COSM5480451,Something is odd...,0,NO,NO,NO,NO,NO,NO,"-1,96",Neutral,0,Damaging,"31,37","33,07"
"inspected, many artifacts",UPN2_091,2,25497851,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys200*/c.598A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|A),3058,35,3101,"0,0112866817",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,97","33,06"
"low freq, many artifacts",UPN2_050,2,25497854,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser199Gly/c.595A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|C),5036,55,5121,"0,0107400898",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,5",Neutral,"0,014",Damaging,"32,07","32,58"
"low freq, many artifacts",UPN2_054,2,25497854,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser199Gly/c.595A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|C),3468,48,3544,"0,0135440181",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,5",Neutral,"0,014",Damaging,"32,02","33,19"
"inspected, many artifacts",UPN2_002,2,25497856,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile198Asn/c.593T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|T),2316,27,2345,"0,0115138593",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,"0,013",Damaging,"33,84","28,37"
"low freq, many artifacts",UPN2_041,2,25497865,G,A,missense_variant(MODERATE|MISSENSE|cCc/cTc|p.Pro195Leu/c.584C>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|A),2571,54,2636,"0,0204855842",0,0,0,0,1,1,0,1,3,NO,NO,COSM3372728,thyroid,1,NO,NO,NO,NO,NO,NO,"-1,93",Neutral,"0,001",Damaging,"33,48","29,81"
"inspected, many artifacts",UPN2_091,2,25497866,G,A,missense_variant(MODERATE|MISSENSE|Ccc/Tcc|p.Pro195Ser/c.583C>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|A),3068,33,3103,"0,0106348695",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,"0,006",Damaging,"33,89","33,79"
"low freq, many artifacts",UPN2_040,2,25497868,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp194Gly/c.581A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|C),1949,38,2012,"0,0188866799",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,"0,007",Damaging,"28,24","35,58"
"low freq, many artifacts",UPN2_081,2,25497868,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp194Gly/c.581A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|C),3198,46,3427,"0,0134228188",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,"0,007",Damaging,"28,35","32,17"
"low bq, low freq, many artifacts, many samples",UPN2_019,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),3081,43,3135,"0,0137161085",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"27,67","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_020,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),3088,32,3130,"0,0102236422",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"27,95","15,25"
"low bq, low freq, many artifacts, many samples",UPN2_002,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),2313,24,2348,"0,0102214651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"27,57","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_041,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),2566,47,2636,"0,0178300455",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"28,01","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_089,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),2756,55,2820,"0,0195035461",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"30,16","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),7575,125,7768,"0,0160916581",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"28,11","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),4443,79,4552,"0,0173550088",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"28,14","14,33"
"low bq, many samples",UPN2_044,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),1147,26,1181,"0,0220152413",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"28,03","16,38"
"low bq, low freq, many artifacts, many samples",UPN2_029,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),4404,48,4487,"0,0106975708",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"27,91","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),6903,131,7075,"0,0185159011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"27,95","14,1"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),5864,106,6047,"0,0175293534",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"27,97","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),7418,129,7602,"0,0169692186",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"28,22","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_048,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),4313,88,4423,"0,0198959982",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"28,08",14
"low bq, low freq, many artifacts, many samples",UPN2_049,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),4684,73,4804,"0,0151956703",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"28,12","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),5012,85,5122,"0,01659508",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"28,04","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),4285,90,4414,"0,0203896692",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"28,21","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),4679,93,4824,"0,019278607",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"27,99","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),6182,106,6330,"0,0167456556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"28,15","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_007,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),4704,48,4792,"0,0100166945",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"28,09","14,15"
"low bq, low freq, many artifacts, many samples",UPN2_008,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),7455,88,7591,"0,0115926755",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"27,89","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_009,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),5949,67,6048,"0,0110780423",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"27,94","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_010,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),3528,43,3593,"0,011967715",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"27,77","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_011,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),3251,35,3298,"0,0106124924",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"27,9","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_056,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),2182,42,2232,"0,0188172043",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"28,34","15,9"
"low bq, low freq, many artifacts, many samples",UPN2_090,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),2349,28,2382,"0,0117548279",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"30,12","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),5141,91,5272,"0,0172610015",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"27,97","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),5509,107,5651,"0,0189347018",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"28,13","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_012,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),2426,32,2470,"0,0129554656",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"27,96",14
"low bq, many samples",UPN2_060,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),1134,60,1199,"0,0500417014",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"28,14","15,85"
"low bq, low freq, many artifacts, many samples",UPN2_091,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),3048,48,3103,"0,0154689011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"30,14","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_093,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),2052,22,2088,"0,0105363985",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"30,55",14
"low bq, many samples",UPN2_061,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),1231,52,1290,"0,0403100775",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"28,01","14,75"
"low bq, many samples",UPN2_062,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),2160,143,2319,"0,0616645106",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"28,22","14,75"
"low bq, many samples",UPN2_063,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),1128,48,1184,"0,0405405405",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"28,08","15,75"
"low bq, many samples",UPN2_064,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),731,45,780,"0,0576923077",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"28,25","14,84"
"low bq, many samples",UPN2_069,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),684,39,727,"0,0536451169",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"28,08","14,79"
"low bq, many samples",UPN2_071,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),2774,115,2920,"0,0393835616",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"28,17","14,89"
"low bq, many samples",UPN2_072,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),2147,120,2272,"0,0528169014",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"28,22","15,32"
"low bq, many samples",UPN2_073,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),856,32,894,"0,0357941834",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"27,82","15,03"
"low bq, many samples",UPN2_075,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),1688,69,1763,"0,0391378332",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"28,57","14,2"
"low bq, many samples",UPN2_076,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),1000,56,1076,"0,0520446097",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"28,21","15,62"
"low bq, many samples",UPN2_077,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),617,31,656,"0,0472560976",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"28,09","14,58"
"low bq, many samples",UPN2_079,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),732,38,778,"0,0488431877",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"28,05","14,68"
"low bq, many samples",UPN2_080,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),1557,80,1643,"0,0486914181",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"28,23","14,85"
"low bq, many samples",UPN2_083,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),1182,59,1250,"0,0472",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"28,46","15,27"
"low bq, many samples",UPN2_084,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),836,33,872,"0,0378440367",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"28,06","14,21"
"low bq, many samples",UPN2_085,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),417,21,443,"0,0474040632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"28,51",14
"low bq, many samples",UPN2_087,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),426,20,446,"0,0448430493",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"28,32","16,85"
"low bq, many samples",UPN2_088,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),514,23,544,"0,0422794118",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"28,23","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_094,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),4682,74,4774,"0,0155006284",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"30,11","15,49"
"low bq, low freq, many artifacts, many samples",UPN2_095,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),4236,65,4321,"0,0150428142",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"30,32","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_096,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),4046,53,4112,"0,0128891051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"30,31","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_097,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),4512,74,4613,"0,0160416215",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"30,11","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_098,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),2774,37,2824,"0,013101983",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"30,22","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_100,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),3238,54,3313,"0,0162994265",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"30,4","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_101,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),2829,52,2902,"0,0179186768",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"30,02","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_102,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),3427,52,3502,"0,0148486579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"30,27","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_103,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),3039,48,3115,"0,0154093098",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"29,98","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_104,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),3983,58,4057,"0,014296278",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"30,34","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_105,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),3217,33,3253,"0,010144482",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"30,22","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_106,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),5370,89,5475,"0,0162557078",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"30,34","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_107,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),5640,77,5758,"0,0133726989",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"30,25","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_108,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),5565,85,5679,"0,0149674238",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"30,43","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_109,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),4479,62,4557,"0,0136054422",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"30,23","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_110,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),5230,71,5337,"0,0133033539",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,"30,07","14,28"
"low bq, low freq, many artifacts",UPN2_111,2,25497868,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp194Ala/c.581A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),3763,53,3843,"0,0137913089",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,01",Damaging,30,"14,26"
"many samples, homopolymer 5C, low freq, no database",UPN2_030,2,25497868,TC,T,frameshift_variant(HIGH||gac/|p.Asp194fs/c.580delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|T),4451,52,4506,"0,0115401687",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,96",NA
"many samples, homopolymer 5C, low freq, no database",UPN2_035,2,25497868,TC,T,frameshift_variant(HIGH||gac/|p.Asp194fs/c.580delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|T),3379,59,3444,"0,0171312427",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,01",NA
"many samples, homopolymer 5C, low freq, no database",UPN2_054,2,25497868,TC,T,frameshift_variant(HIGH||gac/|p.Asp194fs/c.580delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|T),3495,48,3545,"0,0135401975",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,35,NA
"many samples, homopolymer 5C, low freq, no database",UPN2_055,2,25497868,TC,T,frameshift_variant(HIGH||gac/|p.Asp194fs/c.580delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|T),6634,77,6726,"0,0114481118",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,85",NA
"many samples, homopolymer 5C, low freq, no database",UPN2_078,2,25497868,TC,T,frameshift_variant(HIGH||gac/|p.Asp194fs/c.580delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|T),1498,22,1547,"0,014221073",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,75",NA
"low freq, many artifacts",UPN2_078,2,25497869,C,T,missense_variant(MODERATE|MISSENSE|Gac/Aac|p.Asp194Asn/c.580G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|T),1498,26,1547,"0,0168067227",0,0,0,0,0,0,0,1,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,9,Damaging,"34,75","31,88"
"many samples, low bq, low freq",UPN2_002,2,25497877,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln191Leu/c.572A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|A),2315,25,2348,"0,0106473595",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,0,Damaging,"32,32","28,8"
"many samples, low bq, low freq",UPN2_047,2,25497877,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln191Leu/c.572A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|A),7426,141,7600,"0,0185526316",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,0,Damaging,"32,32","27,01"
"many samples, low bq, low freq",UPN2_036,2,25497877,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln191Leu/c.572A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|A),4321,62,4399,"0,0140941123",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,0,Damaging,"32,78","28,71"
"many samples, low bq, low freq",UPN2_049,2,25497877,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln191Leu/c.572A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|A),4731,55,4804,"0,0114487927",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,0,Damaging,"32,32","25,71"
"low bq, low freq, many artifacts",UPN2_051,2,25497877,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln191Leu/c.572A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|A),4342,45,4413,"0,0101971448",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,0,Damaging,"32,62","20,76"
"low freq, many artifacts",UPN2_044,2,25497881,A,G,missense_variant(MODERATE|MISSENSE|Ttc/Ctc|p.Phe190Leu/c.568T>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),1156,21,1182,"0,0177664975",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,029",Damaging,"32,82","31,24"
"inspected, not in 2nd illumina, not in 454",UPN2_006,2,25497883,G,A,missense_variant(MODERATE|MISSENSE|aCc/aTc|p.Thr189Ile/c.566C>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|A),868,34,902,"0,0376940133",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,"0,379",Tolerated,"34,28","35,18"
"low freq, many artifacts",UPN2_050,2,25497884,T,A,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr189Ser/c.565A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|A),5029,53,5119,"0,0103535847",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,22",Neutral,34,Damaging,"30,93","28,75"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25497884,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr189Pro/c.565A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),2263,42,2320,"0,0181034483",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,321,Tolerated,"30,94",16
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25497884,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr189Pro/c.565A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),2240,28,2273,"0,0123185218",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,321,Tolerated,"30,69","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25497884,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr189Pro/c.565A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),1523,20,1546,"0,0129366106",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,321,Tolerated,"30,37",15
"low bq, low freq, many artifacts",UPN2_080,2,25497884,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr189Pro/c.565A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|G),1607,23,1644,"0,0139902676",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,321,Tolerated,"30,68","14,78"
"low freq, many artifacts",UPN2_051,2,25497892,G,A,missense_variant(MODERATE|MISSENSE|cCg/cTg|p.Pro186Leu/c.557C>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|A),4346,51,4411,"0,0115620041",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,3",Deleterious,"0,052",Tolerated,"33,99",33
"low freq, many artifacts",UPN2_052,2,25497892,G,A,missense_variant(MODERATE|MISSENSE|cCg/cTg|p.Pro186Leu/c.557C>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|A),4742,74,4822,"0,0153463293",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,3",Deleterious,"0,052",Tolerated,"33,93",34
"low bq, low freq, many artifacts",UPN2_057,2,25497896,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met185Leu/c.553A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|A),5191,71,5279,"0,013449517",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,24,Damaging,"31,27","23,06"
"inspected, not in 2nd illumina, not in 454",UPN2_004,2,25497896,T,C,missense_variant(MODERATE|MISSENSE|Atg/Gtg|p.Met185Val/c.553A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|C),478,20,500,"0,04",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,"0,015",Damaging,"31,15","34,55"
"low freq, many artifacts",UPN2_010,2,25497898,G,A,missense_variant(MODERATE|MISSENSE|cCc/cTc|p.Pro184Leu/c.551C>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|A),3549,38,3590,"0,0105849582",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,0,Damaging,"34,45","29,5"
"low freq, many artifacts",UPN2_041,2,25497904,T,C,missense_variant(MODERATE|MISSENSE|cAg/cGg|p.Gln182Arg/c.545A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|C),2568,43,2635,"0,0163187856",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,0,Damaging,"31,69","32,05"
"low freq, many artifacts",UPN2_010,2,25497905,G,A,stop_gained(HIGH|NONSENSE|Cag/Tag|p.Gln182*/c.544C>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|A),3538,50,3590,"0,0139275766",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,93","35,16"
"low freq, many artifacts",UPN2_047,2,25497908,G,A,missense_variant(MODERATE|MISSENSE|Cgt/Tgt|p.Arg181Cys/c.541C>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|A),7488,77,7592,"0,010142255",0,0,0,0,1,0,0,1,2,NO,NO,COSM5530099,Something is odd...,0,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,0,Damaging,"32,66","32,32"
"low freq, many artifacts",UPN2_011,2,25497908,G,A,missense_variant(MODERATE|MISSENSE|Cgt/Tgt|p.Arg181Cys/c.541C>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|A),3259,34,3298,"0,0103092784",0,0,0,0,1,0,0,1,2,NO,NO,COSM5530099,Something is odd...,0,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,0,Damaging,"34,32","34,32"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,25497910,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu180Arg/c.539T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|C),5043,52,5113,"0,0101701545",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,0,Damaging,"28,75","21,56"
"low bq, low freq, many artifacts, many samples",UPN2_056,2,25497910,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu180Arg/c.539T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|C),2196,24,2231,"0,0107575078",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,0,Damaging,"28,84","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25497910,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu180Arg/c.539T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|C),1173,21,1198,"0,0175292154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,0,Damaging,"27,42",14
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25497910,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu180Arg/c.539T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|C),2271,39,2316,"0,0168393782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,0,Damaging,"27,41",14
"low bq, many samples",UPN2_063,2,25497910,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu180Arg/c.539T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|C),1149,26,1181,"0,0220152413",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,0,Damaging,"27,39","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25497910,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu180Arg/c.539T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|C),2865,46,2916,"0,0157750343",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,0,Damaging,"27,22","14,15"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25497910,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu180Arg/c.539T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|C),2218,32,2268,"0,0141093474",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,0,Damaging,"27,17",14
"low bq, many samples",UPN2_073,2,25497910,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu180Arg/c.539T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|C),863,25,893,"0,0279955207",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,0,Damaging,"27,27","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25497910,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu180Arg/c.539T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|C),1735,21,1762,"0,0119182747",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,0,Damaging,"27,25",14
"low bq, many samples",UPN2_076,2,25497910,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu180Arg/c.539T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|C),1043,24,1075,"0,0223255814",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,0,Damaging,"27,46",14
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25497910,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu180Arg/c.539T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|C),1507,30,1543,"0,0194426442",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,0,Damaging,"27,44","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25497910,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu180Arg/c.539T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|C),1598,35,1642,"0,0213154689",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,0,Damaging,"27,28","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25497910,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu180Arg/c.539T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|C),3363,44,3421,"0,0128617363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,0,Damaging,"27,16",14
"low bq, low freq, many artifacts",UPN2_083,2,25497910,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu180Arg/c.539T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|C),1222,21,1247,"0,016840417",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,0,Damaging,"27,55",14
"low freq, many artifacts",UPN2_011,2,25497914,TG,T,frameshift_variant(HIGH||tcc/|p.Ser179fs/c.534delC|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|T),3254,37,3296,"0,0112257282",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,9",NA
"low bq, low freq, many artifacts, many samples",UPN2_041,2,25497923,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp176Gly/c.526T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|C),2577,33,2622,"0,0125858124",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,64",Deleterious,7,Damaging,"30,26",14
"low bq, low freq, many artifacts, many samples",UPN2_010,2,25497923,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp176Gly/c.526T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|C),3526,36,3579,"0,0100586756",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,64",Deleterious,7,Damaging,"30,32","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25497923,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp176Gly/c.526T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|C),1161,20,1188,"0,0168350168",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,64",Deleterious,7,Damaging,"28,86",14
"low bq, low freq, many artifacts",UPN2_071,2,25497923,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp176Gly/c.526T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|C),2823,34,2886,"0,0117810118",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,64",Deleterious,7,Damaging,"28,97","15,24"
"low freq, many artifacts",UPN2_036,2,25497925,C,T,missense_variant(MODERATE|MISSENSE|gGc/gAc|p.Gly175Asp/c.524G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|6|T),2496,26,2525,"0,0102970297",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,1,Damaging,"34,5","34,69"
"low bq, low freq, many artifacts",UPN2_044,2,25505310,C,A,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly150Cys/c.448G>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|A),3136,33,3171,"0,0104068117",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,14",Neutral,14,Damaging,"33,95","25,06"
"low bq, low freq, many artifacts",UPN2_083,2,25505336,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu141Ala/c.422A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4213,44,4267,"0,0103116944",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,13,Damaging,"31,31","14,89"
"low freq, many artifacts",UPN2_040,2,25505340,T,TG,frameshift_variant(HIGH||ccc/cccC|p.Lys140fs/c.417dupC|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|TG),1450,22,1466,"0,0150068213",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,24",NA
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25505348,C,G,missense_variant(MODERATE|MISSENSE|tGc/tCc|p.Cys137Ser/c.410G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6778,79,6884,"0,0114758861",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,23",Neutral,5,Damaging,"29,9","14,18"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25505348,C,G,missense_variant(MODERATE|MISSENSE|tGc/tCc|p.Cys137Ser/c.410G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7590,82,7693,"0,0106590407",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,23",Neutral,5,Damaging,"29,87","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25505348,C,G,missense_variant(MODERATE|MISSENSE|tGc/tCc|p.Cys137Ser/c.410G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6998,76,7081,"0,0107329473",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,23",Neutral,5,Damaging,"29,64","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,25505348,C,G,missense_variant(MODERATE|MISSENSE|tGc/tCc|p.Cys137Ser/c.410G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3962,47,4025,"0,0116770186",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,23",Neutral,5,Damaging,"29,84","14,15"
"low bq, low freq, many artifacts, many samples",UPN2_066,2,25505348,C,G,missense_variant(MODERATE|MISSENSE|tGc/tCc|p.Cys137Ser/c.410G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2825,46,2878,"0,0159833218",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,23",Neutral,5,Damaging,"29,71","14,15"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,25505348,C,G,missense_variant(MODERATE|MISSENSE|tGc/tCc|p.Cys137Ser/c.410G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5152,64,5232,"0,0122324159",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,23",Neutral,5,Damaging,"29,56","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25505348,C,G,missense_variant(MODERATE|MISSENSE|tGc/tCc|p.Cys137Ser/c.410G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7775,89,7878,"0,0112972836",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,23",Neutral,5,Damaging,"29,78","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25505348,C,G,missense_variant(MODERATE|MISSENSE|tGc/tCc|p.Cys137Ser/c.410G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),10501,117,10656,"0,0109797297",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,23",Neutral,5,Damaging,"29,78","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25505348,C,G,missense_variant(MODERATE|MISSENSE|tGc/tCc|p.Cys137Ser/c.410G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5960,62,6033,"0,0102768109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,23",Neutral,5,Damaging,"29,78","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,25505348,C,G,missense_variant(MODERATE|MISSENSE|tGc/tCc|p.Cys137Ser/c.410G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2851,29,2883,"0,0100589664",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,23",Neutral,5,Damaging,"29,84","15,79"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25505348,C,G,missense_variant(MODERATE|MISSENSE|tGc/tCc|p.Cys137Ser/c.410G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),10290,133,10439,"0,012740684",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,23",Neutral,5,Damaging,"29,65","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25505348,C,G,missense_variant(MODERATE|MISSENSE|tGc/tCc|p.Cys137Ser/c.410G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7022,86,7121,"0,0120769555",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,23",Neutral,5,Damaging,"29,72","14,08"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25505348,C,G,missense_variant(MODERATE|MISSENSE|tGc/tCc|p.Cys137Ser/c.410G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6531,85,6627,"0,0128263166",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,23",Neutral,5,Damaging,"29,87","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25505348,C,G,missense_variant(MODERATE|MISSENSE|tGc/tCc|p.Cys137Ser/c.410G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8479,90,8577,"0,0104931794",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,23",Neutral,5,Damaging,"29,71","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25505348,C,G,missense_variant(MODERATE|MISSENSE|tGc/tCc|p.Cys137Ser/c.410G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),10385,130,10541,"0,0123327957",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,23",Neutral,5,Damaging,"29,88","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25505348,C,G,missense_variant(MODERATE|MISSENSE|tGc/tCc|p.Cys137Ser/c.410G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),13220,146,13395,"0,0108995894",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,23",Neutral,5,Damaging,"29,74","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25505348,C,G,missense_variant(MODERATE|MISSENSE|tGc/tCc|p.Cys137Ser/c.410G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5623,78,5706,"0,0136698212",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,23",Neutral,5,Damaging,"29,61",14
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25505348,C,G,missense_variant(MODERATE|MISSENSE|tGc/tCc|p.Cys137Ser/c.410G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8751,102,8868,"0,0115020298",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,23",Neutral,5,Damaging,"29,73","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,25505348,C,G,missense_variant(MODERATE|MISSENSE|tGc/tCc|p.Cys137Ser/c.410G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4430,51,4486,"0,0113687026",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,23",Neutral,5,Damaging,"29,9","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_086,2,25505348,C,G,missense_variant(MODERATE|MISSENSE|tGc/tCc|p.Cys137Ser/c.410G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3083,32,3122,"0,0102498398",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,23",Neutral,5,Damaging,"29,52","14,62"
"low bq, low freq, many artifacts",UPN2_087,2,25505348,C,G,missense_variant(MODERATE|MISSENSE|tGc/tCc|p.Cys137Ser/c.410G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8073,88,8182,"0,0107553165",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,23",Neutral,5,Damaging,"29,75",14
"low bq, low freq, many artifacts, many samples",UPN2_059,2,25505349,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys137Gly/c.409T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),5790,75,5907,"0,0126968004",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,83",Neutral,12,Damaging,"28,34","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25505349,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys137Gly/c.409T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),6784,80,6919,"0,0115623645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,83",Neutral,12,Damaging,"28,5","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25505349,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys137Gly/c.409T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),7604,134,7769,"0,0172480371",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,83",Neutral,12,Damaging,"27,97","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25505349,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys137Gly/c.409T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),10636,190,10892,"0,0174439956",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,83",Neutral,12,Damaging,"27,82","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25505349,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys137Gly/c.409T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),8126,133,8329,"0,0159683035",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,83",Neutral,12,Damaging,"27,96","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25505349,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys137Gly/c.409T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),6930,118,7108,"0,0166010129",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,83",Neutral,12,Damaging,"28,25","15,69"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,25505349,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys137Gly/c.409T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),3965,53,4041,"0,0131155655",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,83",Neutral,12,Damaging,"28,31","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_066,2,25505349,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys137Gly/c.409T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),2817,47,2884,"0,01629681",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,83",Neutral,12,Damaging,"28,42","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_067,2,25505349,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys137Gly/c.409T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),3425,47,3493,"0,0134554824",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,83",Neutral,12,Damaging,"28,61","15,4"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25505349,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys137Gly/c.409T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),5423,92,5565,"0,0165318958",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,83",Neutral,12,Damaging,"27,91","15,57"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25505349,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys137Gly/c.409T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),8448,122,8629,"0,0141383706",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,83",Neutral,12,Damaging,"28,12","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,25505349,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys137Gly/c.409T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),5130,77,5252,"0,0146610815",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,83",Neutral,12,Damaging,"27,8","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25505349,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys137Gly/c.409T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),7702,132,7900,"0,0167088608",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,83",Neutral,12,Damaging,"28,12","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25505349,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys137Gly/c.409T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),10459,145,10682,"0,013574237",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,83",Neutral,12,Damaging,"28,44","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25505349,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys137Gly/c.409T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),5912,96,6045,"0,0158808933",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,83",Neutral,12,Damaging,"28,31","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,25505349,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys137Gly/c.409T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),2832,37,2897,"0,0127718329",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,83",Neutral,12,Damaging,"28,45","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25505349,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys137Gly/c.409T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),10277,132,10481,"0,0125942181",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,83",Neutral,12,Damaging,"28,56","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25505349,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys137Gly/c.409T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),7004,104,7134,"0,0145780768",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,83",Neutral,12,Damaging,"27,74","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25505349,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys137Gly/c.409T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),6522,89,6654,"0,0133754133",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,83",Neutral,12,Damaging,"28,06","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25505349,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys137Gly/c.409T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),8427,140,8606,"0,0162677202",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,83",Neutral,12,Damaging,"27,76","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25505349,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys137Gly/c.409T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),6330,101,6478,"0,0155912319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,83",Neutral,12,Damaging,"28,07","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25505349,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys137Gly/c.409T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),10376,133,10585,"0,0125649504",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,83",Neutral,12,Damaging,"28,25","15,53"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25505349,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys137Gly/c.409T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),13204,213,13503,"0,0157742724",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,83",Neutral,12,Damaging,"28,32","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25505349,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys137Gly/c.409T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),5617,87,5732,"0,0151779484",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,83",Neutral,12,Damaging,"28,29","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25505349,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys137Gly/c.409T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),8171,119,8345,"0,0142600359",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,83",Neutral,12,Damaging,"27,74","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25505349,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys137Gly/c.409T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),8728,133,8928,"0,0148969534",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,83",Neutral,12,Damaging,"27,76","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,25505349,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys137Gly/c.409T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),4395,69,4499,"0,0153367415",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,83",Neutral,12,Damaging,"28,16","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_086,2,25505349,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys137Gly/c.409T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),3050,61,3147,"0,0193835399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,83",Neutral,12,Damaging,"27,88","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_087,2,25505349,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys137Gly/c.409T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),8037,135,8213,"0,0164373554",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,83",Neutral,12,Damaging,"28,13","14,76"
"low bq, low freq, many artifacts",UPN2_088,2,25505349,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys137Gly/c.409T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),5198,71,5292,"0,0134164777",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,83",Neutral,12,Damaging,"28,69","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,25505352,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys136Gly/c.406T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),5744,128,5915,"0,0216398986",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,38",Neutral,11,Damaging,"29,34","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25505352,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys136Gly/c.406T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),6766,128,6936,"0,0184544406",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,38",Neutral,11,Damaging,"29,27","15,33"
"low bq, many samples",UPN2_061,2,25505352,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys136Gly/c.406T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),7557,182,7794,"0,0233512959",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,38",Neutral,11,Damaging,"28,9","15,14"
"low bq, many samples",UPN2_062,2,25505352,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys136Gly/c.406T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),10613,267,10925,"0,0244393593",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,38",Neutral,11,Damaging,"28,87","15,66"
"low bq, many samples",UPN2_063,2,25505352,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys136Gly/c.406T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),8120,185,8346,"0,0221663072",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,38",Neutral,11,Damaging,"29,03","15,3"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25505352,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys136Gly/c.406T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),6938,148,7124,"0,0207748456",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,38",Neutral,11,Damaging,"29,07","15,21"
"low bq, many samples",UPN2_065,2,25505352,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys136Gly/c.406T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),3926,101,4050,"0,0249382716",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,38",Neutral,11,Damaging,"29,17","16,51"
"low bq, low freq, many artifacts, many samples",UPN2_066,2,25505352,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys136Gly/c.406T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),2813,57,2893,"0,0197027307",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,38",Neutral,11,Damaging,"29,19","14,68"
"low bq, many samples",UPN2_067,2,25505352,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys136Gly/c.406T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),3397,77,3498,"0,0220125786",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,38",Neutral,11,Damaging,"29,24","15,08"
"low bq, many samples",UPN2_068,2,25505352,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys136Gly/c.406T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),5422,137,5578,"0,0245607745",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,38",Neutral,11,Damaging,"28,92","15,5"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25505352,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys136Gly/c.406T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),8425,185,8649,"0,021389756",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,38",Neutral,11,Damaging,"29,07","14,89"
"low bq, many samples",UPN2_070,2,25505352,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys136Gly/c.406T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),5116,120,5263,"0,022800684",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,38",Neutral,11,Damaging,"28,93","14,65"
"low bq, many samples",UPN2_071,2,25505352,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys136Gly/c.406T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),7689,182,7922,"0,0229739965",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,38",Neutral,11,Damaging,"29,15","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25505352,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys136Gly/c.406T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),10431,209,10703,"0,0195272354",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,38",Neutral,11,Damaging,"29,31","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25505352,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys136Gly/c.406T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),5897,118,6060,"0,0194719472",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,38",Neutral,11,Damaging,"29,28","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,25505352,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys136Gly/c.406T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),2839,49,2905,"0,0168674699",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,38",Neutral,11,Damaging,"29,44","15,69"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25505352,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys136Gly/c.406T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),10255,221,10509,"0,0210295937",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,38",Neutral,11,Damaging,"29,48","15,91"
"low bq, many samples",UPN2_076,2,25505352,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys136Gly/c.406T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),6939,162,7148,"0,0226636821",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,38",Neutral,11,Damaging,"28,89","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25505352,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys136Gly/c.406T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),6487,142,6665,"0,0213053263",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,38",Neutral,11,Damaging,"28,94","15,43"
"low bq, many samples",UPN2_078,2,25505352,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys136Gly/c.406T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),8358,215,8633,"0,0249044365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,38",Neutral,11,Damaging,"28,91","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25505352,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys136Gly/c.406T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),6342,130,6501,"0,0199969236",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,38",Neutral,11,Damaging,"29,14","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25505352,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys136Gly/c.406T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),10313,225,10601,"0,0212244128",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,38",Neutral,11,Damaging,"29,31","15,21"
"low bq, many samples",UPN2_081,2,25505352,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys136Gly/c.406T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),13161,301,13541,"0,0222287866",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,38",Neutral,11,Damaging,"29,26","14,84"
"low bq, many samples",UPN2_082,2,25505352,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys136Gly/c.406T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),5592,127,5749,"0,0220907984",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,38",Neutral,11,Damaging,"29,12","16,33"
"low bq, many samples",UPN2_083,2,25505352,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys136Gly/c.406T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),8078,231,8362,"0,0276249701",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,38",Neutral,11,Damaging,"29,08","15,44"
"low bq, many samples",UPN2_084,2,25505352,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys136Gly/c.406T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),8711,198,8950,"0,022122905",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,38",Neutral,11,Damaging,"29,09","15,51"
"low bq, many samples",UPN2_085,2,25505352,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys136Gly/c.406T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),4398,100,4512,"0,0221631206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,38",Neutral,11,Damaging,"28,95","15,77"
"low bq, many samples",UPN2_086,2,25505352,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys136Gly/c.406T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),3070,75,3157,"0,0237567311",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,38",Neutral,11,Damaging,"28,61","14,83"
"low bq, many samples",UPN2_087,2,25505352,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys136Gly/c.406T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),8003,186,8236,"0,0225837785",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,38",Neutral,11,Damaging,"29,21","15,22"
"low bq, low freq, many artifacts",UPN2_088,2,25505352,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys136Gly/c.406T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),5167,105,5297,"0,0198225411",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,38",Neutral,11,Damaging,"29,45","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,25505356,A,C,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn134Lys/c.402T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),3977,48,4060,"0,0118226601",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,98",Neutral,2,Damaging,"29,72","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25505356,A,C,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn134Lys/c.402T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),8245,89,8374,"0,0106281347",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,98",Neutral,2,Damaging,"29,61","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_086,2,25505356,A,C,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn134Lys/c.402T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),3117,36,3164,"0,0113780025",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,98",Neutral,2,Damaging,"29,42","15,28"
"low bq, bad alignment, many samples",UPN2_059,2,25505357,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn134Thr/c.401A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5714,175,5931,"0,0295059855",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,2,Damaging,"24,72","14,5"
"low bq, bad alignment, many samples",UPN2_060,2,25505357,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn134Thr/c.401A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6699,190,6955,"0,0273184759",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,2,Damaging,"24,83","14,51"
"low bq, bad alignment, many samples",UPN2_061,2,25505357,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn134Thr/c.401A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7487,240,7805,"0,0307495195",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,2,Damaging,"24,33","14,43"
"low bq, bad alignment, many samples",UPN2_062,2,25505357,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn134Thr/c.401A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),10525,335,10949,"0,0305964015",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,2,Damaging,"24,05","14,5"
"low bq, bad alignment, many samples",UPN2_063,2,25505357,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn134Thr/c.401A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8045,265,8371,"0,0316569108",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,2,Damaging,"24,44","14,61"
"low bq, bad alignment, many samples",UPN2_064,2,25505357,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn134Thr/c.401A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6846,237,7137,"0,0332072299",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,2,Damaging,"24,66","14,37"
"low bq, bad alignment, many samples",UPN2_065,2,25505357,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn134Thr/c.401A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3895,123,4060,"0,0302955665",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,2,Damaging,"24,84","14,63"
"low bq, bad alignment, many samples",UPN2_066,2,25505357,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn134Thr/c.401A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2807,71,2900,"0,0244827586",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,2,Damaging,"25,22","14,99"
"low bq, bad alignment, many samples",UPN2_067,2,25505357,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn134Thr/c.401A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3383,89,3507,"0,0253778158",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,2,Damaging,"25,2","14,71"
"low bq, bad alignment, many samples",UPN2_068,2,25505357,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn134Thr/c.401A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5362,183,5585,"0,0327663384",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,2,Damaging,"24,53","14,73"
"low bq, bad alignment, many samples",UPN2_069,2,25505357,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn134Thr/c.401A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8299,298,8677,"0,0343436672",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,2,Damaging,"24,56","14,34"
"low bq, bad alignment, many samples",UPN2_070,2,25505357,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn134Thr/c.401A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5071,172,5279,"0,0325819284",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,2,Damaging,"24,19","14,93"
"low bq, bad alignment, many samples",UPN2_071,2,25505357,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn134Thr/c.401A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7615,246,7934,"0,0310057978",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,2,Damaging,"24,77","14,57"
"low bq, bad alignment, many samples",UPN2_072,2,25505357,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn134Thr/c.401A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),10328,332,10729,"0,03094417",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,2,Damaging,"24,94","14,54"
"low bq, bad alignment, many samples",UPN2_073,2,25505357,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn134Thr/c.401A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5839,179,6072,"0,0294795784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,2,Damaging,"24,91","14,46"
"low bq, bad alignment, many samples",UPN2_074,2,25505357,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn134Thr/c.401A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2818,71,2911,"0,0243902439",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,2,Damaging,"24,8","14,2"
"low bq, bad alignment, many samples",UPN2_075,2,25505357,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn134Thr/c.401A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),10177,272,10540,"0,0258064516",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,2,Damaging,"25,06","14,59"
"low bq, bad alignment, many samples",UPN2_076,2,25505357,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn134Thr/c.401A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6870,230,7155,"0,0321453529",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,2,Damaging,"24,1","14,29"
"low bq, bad alignment, many samples",UPN2_077,2,25505357,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn134Thr/c.401A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6382,219,6673,"0,0328188221",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,2,Damaging,"24,59","14,53"
"low bq, bad alignment, many samples",UPN2_078,2,25505357,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn134Thr/c.401A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8302,282,8660,"0,0325635104",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,2,Damaging,"24,08","14,28"
"low bq, bad alignment, many samples",UPN2_079,2,25505357,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn134Thr/c.401A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6253,201,6518,"0,0308376803",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,2,Damaging,"24,55","14,28"
"low bq, bad alignment, many samples",UPN2_080,2,25505357,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn134Thr/c.401A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),10243,329,10629,"0,030953053",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,2,Damaging,"24,71","14,92"
"low bq, bad alignment, many samples",UPN2_081,2,25505357,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn134Thr/c.401A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),13071,400,13574,"0,0294681008",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,2,Damaging,"24,97","14,35"
"low bq, bad alignment, many samples",UPN2_082,2,25505357,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn134Thr/c.401A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5520,187,5753,"0,0325047801",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,2,Damaging,"24,66","14,91"
"low bq, bad alignment, many samples",UPN2_083,2,25505357,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn134Thr/c.401A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8027,272,8378,"0,0324659823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,2,Damaging,"24,22","14,64"
"low bq, bad alignment, many samples",UPN2_084,2,25505357,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn134Thr/c.401A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8592,289,8965,"0,0322364752",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,2,Damaging,"24,47","14,58"
"low bq, bad alignment, many samples",UPN2_085,2,25505357,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn134Thr/c.401A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4328,149,4528,"0,0329063604",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,2,Damaging,"24,51","15,06"
"low bq, bad alignment, many samples",UPN2_086,2,25505357,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn134Thr/c.401A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3047,105,3167,"0,0331544048",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,2,Damaging,"24,38","15,04"
"low bq, bad alignment, many samples",UPN2_087,2,25505357,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn134Thr/c.401A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7947,254,8252,"0,0307804169",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,2,Damaging,"24,69","14,7"
"low bq, bad alignment",UPN2_088,2,25505357,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn134Thr/c.401A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5120,135,5307,"0,0254381006",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,2,Damaging,"25,06","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,25505358,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn134His/c.400A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5813,65,5934,"0,0109538254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,2,Damaging,"27,6","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25505358,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn134His/c.400A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6838,77,6957,"0,0110679891",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,2,Damaging,"27,78","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25505358,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn134His/c.400A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7650,84,7808,"0,0107581967",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,2,Damaging,"27,37","15,68"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25505358,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn134His/c.400A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),10749,120,10951,"0,0109579034",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,2,Damaging,"27,18","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25505358,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn134His/c.400A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8212,94,8368,"0,0112332696",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,2,Damaging,"27,5","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25505358,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn134His/c.400A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7010,79,7140,"0,0110644258",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,2,Damaging,"27,77","14,09"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,25505358,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn134His/c.400A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3989,44,4061,"0,0108347698",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,2,Damaging,"27,75","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_066,2,25505358,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn134His/c.400A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2853,30,2901,"0,0103412616",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,2,Damaging,"27,95","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_067,2,25505358,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn134His/c.400A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3456,36,3507,"0,0102651839",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,2,Damaging,"28,28",14
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25505358,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn134His/c.400A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5477,81,5585,"0,0145031334",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,2,Damaging,"27,5","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25505358,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn134His/c.400A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7782,84,7933,"0,0105886802",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,2,Damaging,"27,75","14,15"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25505358,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn134His/c.400A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5969,61,6071,"0,0100477681",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,2,Damaging,"27,71","14,11"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,25505358,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn134His/c.400A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2862,30,2910,"0,0103092784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,2,Damaging,"27,69","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25505358,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn134His/c.400A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),10380,106,10547,"0,0100502513",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,2,Damaging,"27,95","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25505358,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn134His/c.400A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7024,76,7151,"0,0106278842",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,2,Damaging,"27,2","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25505358,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn134His/c.400A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8507,101,8662,"0,0116601247",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,2,Damaging,"27,25","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25505358,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn134His/c.400A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),10427,107,10628,"0,0100677456",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,2,Damaging,"27,81","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25505358,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn134His/c.400A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),13344,137,13574,"0,0100928245",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,2,Damaging,"27,93","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25505358,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn134His/c.400A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5662,59,5754,"0,0102537365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,2,Damaging,"27,85","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25505358,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn134His/c.400A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8206,95,8374,"0,0113446382",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,2,Damaging,"27,4","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25505358,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn134His/c.400A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8799,99,8963,"0,0110454089",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,2,Damaging,"27,57","14,52"
"low bq, low freq, many artifacts",UPN2_086,2,25505358,T,G,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn134His/c.400A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3104,39,3168,"0,0123106061",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,2,Damaging,"27,41",14
"low bq, bad alignment, many samples",UPN2_059,2,25505363,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val132Gly/c.395T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),5702,172,5936,"0,0289757412",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,3,Damaging,"25,01","14,85"
"low bq, bad alignment, many samples",UPN2_060,2,25505363,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val132Gly/c.395T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),6685,192,6957,"0,0275981026",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,3,Damaging,"25,41","14,46"
"low bq, bad alignment, many samples",UPN2_061,2,25505363,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val132Gly/c.395T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),7483,243,7805,"0,0311338885",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,3,Damaging,"24,74","14,84"
"low bq, bad alignment, many samples",UPN2_062,2,25505363,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val132Gly/c.395T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),10481,345,10948,"0,031512605",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,3,Damaging,"24,74","15,09"
"low bq, bad alignment, many samples",UPN2_063,2,25505363,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val132Gly/c.395T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),8005,250,8363,"0,0298935789",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,3,Damaging,"24,85","14,79"
"low bq, bad alignment, many samples",UPN2_064,2,25505363,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val132Gly/c.395T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),6844,211,7139,"0,0295559602",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,3,Damaging,"25,1","14,75"
"low bq, bad alignment, many samples",UPN2_065,2,25505363,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val132Gly/c.395T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),3893,121,4062,"0,0297882816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,3,Damaging,"25,15","14,45"
"low bq, bad alignment, many samples",UPN2_066,2,25505363,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val132Gly/c.395T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),2776,89,2900,"0,0306896552",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,3,Damaging,"25,27","14,72"
"low bq, bad alignment, many samples",UPN2_067,2,25505363,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val132Gly/c.395T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),3366,107,3508,"0,0305017104",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,3,Damaging,"25,64","14,24"
"low bq, bad alignment, many samples",UPN2_068,2,25505363,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val132Gly/c.395T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),5360,179,5588,"0,0320329277",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,3,Damaging,"24,92","14,78"
"low bq, bad alignment, many samples",UPN2_069,2,25505363,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val132Gly/c.395T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),8315,269,8676,"0,0310050715",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,3,Damaging,"25,18","14,8"
"low bq, bad alignment, many samples",UPN2_070,2,25505363,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val132Gly/c.395T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),5063,158,5279,"0,029929911",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,3,Damaging,"24,9","14,77"
"low bq, bad alignment, many samples",UPN2_071,2,25505363,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val132Gly/c.395T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),7603,249,7935,"0,0313799622",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,3,Damaging,"25,13","14,63"
"low bq, bad alignment, many samples",UPN2_072,2,25505363,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val132Gly/c.395T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),10315,316,10734,"0,0294391653",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,3,Damaging,"25,38","14,42"
"low bq, bad alignment, many samples",UPN2_073,2,25505363,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val132Gly/c.395T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),5788,210,6072,"0,0345849802",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,3,Damaging,"25,36","14,82"
"low bq, bad alignment, many samples",UPN2_074,2,25505363,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val132Gly/c.395T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),2812,78,2910,"0,0268041237",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,3,Damaging,"25,33","14,59"
"low bq, bad alignment, many samples",UPN2_075,2,25505363,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val132Gly/c.395T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),10148,291,10544,"0,0275986343",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,3,Damaging,"25,65","14,79"
"low bq, bad alignment, many samples",UPN2_076,2,25505363,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val132Gly/c.395T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),6842,223,7146,"0,0312062692",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,3,Damaging,"24,86","14,84"
"low bq, bad alignment, many samples",UPN2_077,2,25505363,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val132Gly/c.395T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),6403,203,6673,"0,0304211",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,3,Damaging,"24,94","15,06"
"low bq, bad alignment, many samples",UPN2_078,2,25505363,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val132Gly/c.395T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),8298,278,8660,"0,0321016166",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,3,Damaging,"24,64","14,73"
"low bq, bad alignment, many samples",UPN2_079,2,25505363,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val132Gly/c.395T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),6264,197,6518,"0,0302239951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,3,Damaging,"25,24","14,67"
"low bq, bad alignment, many samples",UPN2_080,2,25505363,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val132Gly/c.395T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),10195,327,10629,"0,0307648885",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,3,Damaging,"25,27","14,61"
"low bq, bad alignment, many samples",UPN2_081,2,25505363,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val132Gly/c.395T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),13013,399,13572,"0,0293987622",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,3,Damaging,"25,19","14,69"
"low bq, bad alignment, many samples",UPN2_082,2,25505363,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val132Gly/c.395T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),5559,155,5758,"0,0269190691",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,3,Damaging,"25,18","14,7"
"low bq, bad alignment, many samples",UPN2_083,2,25505363,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val132Gly/c.395T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),8034,263,8375,"0,0314029851",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,3,Damaging,"24,84","14,32"
"low bq, bad alignment, many samples",UPN2_084,2,25505363,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val132Gly/c.395T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),8586,282,8961,"0,031469702",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,3,Damaging,25,"14,55"
"low bq, bad alignment, many samples",UPN2_085,2,25505363,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val132Gly/c.395T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),4328,160,4529,"0,035327887",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,3,Damaging,"24,95","14,48"
"low bq, bad alignment, many samples",UPN2_086,2,25505363,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val132Gly/c.395T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),3034,97,3166,"0,0306380291",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,3,Damaging,"24,56","14,34"
"low bq, bad alignment, many samples",UPN2_087,2,25505363,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val132Gly/c.395T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),7904,250,8251,"0,0302993577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,3,Damaging,"25,33","14,78"
"low bq, bad alignment",UPN2_088,2,25505363,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val132Gly/c.395T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),5105,143,5307,"0,0269455436",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,3,Damaging,"25,74","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_041,2,25505363,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val132Glu/c.395T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),39845,556,40839,"0,0136144372",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,6,Damaging,"28,37","20,81"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,25505363,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val132Glu/c.395T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),34546,482,35338,"0,013639708",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,6,Damaging,"28,35","22,56"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,25505363,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val132Glu/c.395T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),22382,253,22817,"0,0110882237",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,6,Damaging,"28,43","19,85"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,25505363,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val132Glu/c.395T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),6134,74,6248,"0,01184379",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,6,Damaging,"28,12","17,08"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,25505363,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val132Glu/c.395T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),32188,386,32902,"0,0117318096",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,6,Damaging,"28,26","19,82"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,25505363,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val132Glu/c.395T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),27124,304,27680,"0,010982659",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,6,Damaging,"28,27","20,03"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,25505363,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val132Glu/c.395T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),42968,497,43852,"0,0113335766",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,6,Damaging,"28,4","19,1"
"low bq, low freq, many artifacts, many samples",UPN2_048,2,25505363,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val132Glu/c.395T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),37100,405,37829,"0,0107060721",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,6,Damaging,"28,31","17,65"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,25505363,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val132Glu/c.395T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),29065,310,29629,"0,0104627223",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,6,Damaging,"28,28","19,92"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,25505363,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val132Glu/c.395T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),20586,242,21013,"0,0115166802",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,6,Damaging,"28,4","18,79"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,25505363,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val132Glu/c.395T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),24947,315,25509,"0,0123485829",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,6,Damaging,"28,26","20,34"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,25505363,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val132Glu/c.395T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),30397,374,31077,"0,0120346237",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,6,Damaging,"28,23","19,17"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,25505363,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val132Glu/c.395T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),19244,235,19671,"0,0119465203",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,6,Damaging,"28,19","19,63"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,25505363,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val132Glu/c.395T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),30067,374,30699,"0,0121828073",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,6,Damaging,"28,34","20,09"
"low bq, low freq, many artifacts, many samples",UPN2_056,2,25505363,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val132Glu/c.395T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),18957,233,19416,"0,012000412",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,6,Damaging,"28,32","19,57"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,25505363,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val132Glu/c.395T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),27748,376,28354,"0,0132609156",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,6,Damaging,"28,35","20,33"
"low bq, low freq, many artifacts",UPN2_058,2,25505363,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val132Glu/c.395T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),29403,427,30118,"0,0141775682",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,6,Damaging,"28,57","20,12"
"low freq, many artifacts",UPN2_040,2,25505363,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val132Glu/c.395T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),2834,48,2893,"0,0165917732",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,"0,006",Damaging,"28,72","29,27"
"low bq, many samples",UPN2_059,2,25505368,T,G,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg130Ser/c.390A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5756,146,5933,"0,0246081241",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,33",Neutral,2,Damaging,"27,42","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25505368,T,G,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg130Ser/c.390A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6776,128,6955,"0,0184040259",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,33",Neutral,2,Damaging,"27,5","14,31"
"low bq, many samples",UPN2_061,2,25505368,T,G,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg130Ser/c.390A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7581,184,7802,"0,0235836965",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,33",Neutral,2,Damaging,"27,01","14,39"
"low bq, many samples",UPN2_062,2,25505368,T,G,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg130Ser/c.390A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),10647,267,10954,"0,0243746577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,33",Neutral,2,Damaging,"27,09","14,53"
"low bq, many samples",UPN2_063,2,25505368,T,G,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg130Ser/c.390A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8145,193,8368,"0,0230640535",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,33",Neutral,2,Damaging,"27,1","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25505368,T,G,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg130Ser/c.390A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6954,156,7139,"0,0218518",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,33",Neutral,2,Damaging,"27,27","14,55"
"low bq, many samples",UPN2_065,2,25505368,T,G,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg130Ser/c.390A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3964,90,4064,"0,0221456693",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,33",Neutral,2,Damaging,"27,52","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_066,2,25505368,T,G,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg130Ser/c.390A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2852,44,2902,"0,0151619573",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,33",Neutral,2,Damaging,"27,75",14
"low bq, low freq, many artifacts, many samples",UPN2_067,2,25505368,T,G,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg130Ser/c.390A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3426,71,3508,"0,0202394527",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,33",Neutral,2,Damaging,"27,48","14,37"
"low bq, many samples",UPN2_068,2,25505368,T,G,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg130Ser/c.390A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5440,130,5593,"0,0232433399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,33",Neutral,2,Damaging,"27,35","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25505368,T,G,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg130Ser/c.390A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8440,189,8679,"0,0217767024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,33",Neutral,2,Damaging,"27,31","14,66"
"low bq, bad alignment, many samples",UPN2_070,2,25505368,T,G,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg130Ser/c.390A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5142,121,5284,"0,0228993187",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,33",Neutral,2,Damaging,"26,89","14,17"
"low bq, many samples",UPN2_071,2,25505368,T,G,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg130Ser/c.390A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7705,185,7935,"0,0233144297",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,33",Neutral,2,Damaging,"27,36","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25505368,T,G,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg130Ser/c.390A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),10501,202,10738,"0,0188116968",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,33",Neutral,2,Damaging,"27,45","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25505368,T,G,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg130Ser/c.390A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5933,125,6071,"0,0205896887",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,33",Neutral,2,Damaging,"27,5","14,16"
"low bq, many samples",UPN2_074,2,25505368,T,G,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg130Ser/c.390A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2819,77,2909,"0,0264695772",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,33",Neutral,2,Damaging,"27,84","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25505368,T,G,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg130Ser/c.390A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),10296,201,10555,"0,0190431075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,33",Neutral,2,Damaging,"27,55","14,21"
"low bq, many samples",UPN2_076,2,25505368,T,G,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg130Ser/c.390A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6930,191,7149,"0,0267170234",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,33",Neutral,2,Damaging,"27,14","14,19"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25505368,T,G,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg130Ser/c.390A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6498,143,6677,"0,021416804",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,33",Neutral,2,Damaging,"27,07","14,48"
"low bq, bad alignment, many samples",UPN2_078,2,25505368,T,G,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg130Ser/c.390A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8430,200,8661,"0,0230920217",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,33",Neutral,2,Damaging,"26,96","14,49"
"low bq, many samples",UPN2_079,2,25505368,T,G,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg130Ser/c.390A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6343,145,6515,"0,0222563315",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,33",Neutral,2,Damaging,"27,09","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25505368,T,G,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg130Ser/c.390A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),10362,202,10628,"0,0190063982",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,33",Neutral,2,Damaging,"27,3","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25505368,T,G,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg130Ser/c.390A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),13227,277,13574,"0,0204066598",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,33",Neutral,2,Damaging,"27,38","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25505368,T,G,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg130Ser/c.390A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5641,109,5764,"0,0189104788",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,33",Neutral,2,Damaging,"27,34","14,28"
"low bq, many samples",UPN2_083,2,25505368,T,G,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg130Ser/c.390A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8146,199,8381,"0,0237441833",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,33",Neutral,2,Damaging,"27,04","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25505368,T,G,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg130Ser/c.390A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8744,188,8957,"0,0209891705",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,33",Neutral,2,Damaging,"27,15","14,32"
"low bq, many samples",UPN2_085,2,25505368,T,G,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg130Ser/c.390A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4398,106,4526,"0,0234202386",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,33",Neutral,2,Damaging,"27,17","14,83"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,2,25505368,T,G,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg130Ser/c.390A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3082,68,3168,"0,0214646465",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,33",Neutral,2,Damaging,"26,9","14,37"
"low bq, many samples",UPN2_087,2,25505368,T,G,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg130Ser/c.390A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8033,187,8255,"0,0226529376",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,33",Neutral,2,Damaging,"27,31","14,91"
"low bq, low freq, many artifacts",UPN2_088,2,25505368,T,G,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg130Ser/c.390A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5185,105,5313,"0,0197628458",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,33",Neutral,2,Damaging,"27,5","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,25505373,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser129Ala/c.385T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),5774,101,5909,"0,0170925707",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,44",Neutral,123,Tolerated,"28,01","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,25505373,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser129Ala/c.385T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),6804,103,6938,"0,0148457769",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,44",Neutral,123,Tolerated,"28,01","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25505373,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser129Ala/c.385T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),7607,134,7779,"0,0172258645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,44",Neutral,123,Tolerated,"27,76","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25505373,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser129Ala/c.385T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),10654,193,10911,"0,0176885712",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,44",Neutral,123,Tolerated,"27,68","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25505373,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser129Ala/c.385T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),8145,127,8331,"0,0152442684",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,44",Neutral,123,Tolerated,"27,86","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,25505373,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser129Ala/c.385T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),6940,121,7110,"0,0170182841",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,44",Neutral,123,Tolerated,"28,03","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,25505373,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser129Ala/c.385T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),3964,60,4050,"0,0148148148",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,44",Neutral,123,Tolerated,"28,06","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_066,2,25505373,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser129Ala/c.385T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),2833,47,2896,"0,0162292818",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,44",Neutral,123,Tolerated,28,"14,66"
"low bq, low freq, many artifacts, many samples",UPN2_067,2,25505373,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser129Ala/c.385T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),3434,50,3501,"0,0142816338",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,44",Neutral,123,Tolerated,"28,28","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25505373,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser129Ala/c.385T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),5452,75,5569,"0,0134674089",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,44",Neutral,123,Tolerated,"28,12","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25505373,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser129Ala/c.385T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),8461,134,8647,"0,0154967041",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,44",Neutral,123,Tolerated,"28,19","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,25505373,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser129Ala/c.385T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),5149,75,5260,"0,0142585551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,44",Neutral,123,Tolerated,"27,77","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25505373,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser129Ala/c.385T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),7732,126,7904,"0,0159412955",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,44",Neutral,123,Tolerated,"28,16","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25505373,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser129Ala/c.385T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),10489,168,10708,"0,0156892043",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,44",Neutral,123,Tolerated,"28,25","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,25505373,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser129Ala/c.385T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),5930,89,6056,"0,0146961691",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,44",Neutral,123,Tolerated,"27,91","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,25505373,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser129Ala/c.385T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),2841,41,2897,"0,0141525716",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,44",Neutral,123,Tolerated,"28,12","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,25505373,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser129Ala/c.385T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),10300,146,10519,"0,0138796464",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,44",Neutral,123,Tolerated,"28,03","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25505373,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser129Ala/c.385T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),6998,94,7129,"0,01318558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,44",Neutral,123,Tolerated,"27,87","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25505373,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser129Ala/c.385T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),6502,102,6648,"0,0153429603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,44",Neutral,123,Tolerated,"27,8","14,13"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25505373,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser129Ala/c.385T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),8444,123,8624,"0,0142625232",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,44",Neutral,123,Tolerated,"27,69","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25505373,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser129Ala/c.385T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),6369,103,6505,"0,0158339739",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,44",Neutral,123,Tolerated,"27,86","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25505373,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser129Ala/c.385T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),10348,165,10590,"0,0155807365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,44",Neutral,123,Tolerated,"27,92","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25505373,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser129Ala/c.385T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),13242,182,13533,"0,0134486071",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,44",Neutral,123,Tolerated,"28,26","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25505373,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser129Ala/c.385T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),5633,89,5753,"0,0154701895",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,44",Neutral,123,Tolerated,"27,98","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25505373,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser129Ala/c.385T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),8173,129,8347,"0,0154546544",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,44",Neutral,123,Tolerated,"27,72","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25505373,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser129Ala/c.385T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),8739,133,8918,"0,0149136578",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,44",Neutral,123,Tolerated,"27,96","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,25505373,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser129Ala/c.385T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),4411,87,4516,"0,0192648361",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,44",Neutral,123,Tolerated,"28,19","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_086,2,25505373,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser129Ala/c.385T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),3092,52,3159,"0,0164609053",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,44",Neutral,123,Tolerated,"27,77","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_087,2,25505373,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser129Ala/c.385T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),8031,134,8234,"0,0162739859",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,44",Neutral,123,Tolerated,"28,27","14,25"
"low bq, low freq, many artifacts",UPN2_088,2,25505373,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser129Ala/c.385T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),5200,73,5299,"0,0137761842",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,44",Neutral,123,Tolerated,"28,06","14,18"
"low bq, bad alignment, many samples",UPN2_001,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8951,209,9236,"0,0226288437",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"25,36","14,51"
"low bq, bad alignment, many samples",UPN2_014,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),14632,430,15162,"0,0283603746",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,08","15,85"
"low bq, bad alignment, many samples",UPN2_015,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),21408,770,22335,"0,0344750392",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"25,7","15,49"
"low bq, bad alignment, many samples",UPN2_016,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8917,244,9217,"0,026472822",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,39","15,5"
"low bq, bad alignment, many samples",UPN2_017,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6741,251,7022,"0,0357448021",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,01","15,54"
"low bq, bad alignment, many samples",UPN2_018,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),9903,303,10277,"0,0294833123",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,03","15,43"
"low bq, bad alignment, many samples",UPN2_019,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),10926,358,11361,"0,0315113106",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"25,84","16,14"
"low bq, bad alignment, many samples",UPN2_020,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),10456,319,10828,"0,0294606576",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,04","15,84"
"low bq, bad alignment, many samples",UPN2_021,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),11015,357,11435,"0,0312199388",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,08","15,62"
"low bq, bad alignment, many samples",UPN2_002,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),12441,390,12909,"0,0302114804",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"24,72","15,32"
"low bq, bad alignment, many samples",UPN2_003,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2224,61,2294,"0,0265911072",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"24,58","16,21"
"low bq, bad alignment, many samples",UPN2_022,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),14114,458,14679,"0,0312010355",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,05","15,64"
"low bq, bad alignment, many samples",UPN2_023,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),17211,532,17863,"0,0297822314",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"25,99","15,86"
"low bq, low freq, many artifacts, many samples",UPN2_041,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),39511,820,40655,"0,0201697208",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"27,03","15,26"
"low bq, bad alignment, many samples",UPN2_024,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7991,243,8300,"0,0292771084",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,22","15,56"
"low bq, bad alignment, many samples",UPN2_025,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),17096,484,17695,"0,0273523594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,25","15,85"
"low bq, bad alignment, many samples",UPN2_026,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),16758,637,17512,"0,0363750571",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"25,65","15,58"
"low bq, bad alignment, many samples",UPN2_004,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2068,78,2162,"0,0360777058",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"24,64","14,99"
"low bq, bad alignment, many samples",UPN2_027,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),18429,641,19188,"0,0334062956",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"25,87","15,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_089,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),13730,180,13952,"0,0129013761",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,89","14,84"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),34171,694,35140,"0,0197495731",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,89","15,36"
"low bq, bad alignment, many samples",UPN2_028,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),14180,474,14777,"0,0320768762",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"25,66","15,79"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),22034,431,22669,"0,0190127487",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"27,14","15,67"
"low bq, bad alignment, many samples",UPN2_044,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5990,150,6188,"0,0242404654",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,62","15,66"
"low bq, bad alignment, many samples",UPN2_029,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),17822,619,18548,"0,0333728704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"25,96","15,45"
"low bq, bad alignment, many samples",UPN2_030,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),17591,580,18314,"0,0316697608",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"25,99","15,66"
"low bq, bad alignment, many samples",UPN2_031,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),10680,354,11108,"0,0318689233",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,1","15,46"
"low bq, bad alignment, many samples",UPN2_005,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3631,111,3766,"0,0294742432",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"24,88","14,69"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),31832,668,32716,"0,020418144",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,87","15,64"
"low bq, bad alignment, many samples",UPN2_032,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6545,172,6755,"0,0254626203",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,06","15,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),26751,603,27535,"0,0218994008",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,79","15,58"
"low bq, bad alignment, many samples",UPN2_033,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),11506,336,11931,"0,0281619311",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,17","15,52"
"low bq, bad alignment, many samples",UPN2_034,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5071,188,5303,"0,0354516312",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"25,91","15,71"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),42340,897,43563,"0,0205908684",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"27,07","15,17"
"low bq, low freq, many artifacts, many samples",UPN2_048,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),36557,811,37625,"0,0215548173",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"27,07","15,46"
"low bq, bad alignment, many samples",UPN2_035,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),12094,330,12511,"0,0263767884",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,22","15,61"
"low bq, bad alignment, many samples",UPN2_036,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),10519,319,10875,"0,0293333333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"25,99","15,7"
"low bq, bad alignment, many samples",UPN2_006,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),10140,292,10500,"0,0278095238",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"25,04","14,9"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),28623,571,29443,"0,0193934042",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,9","15,13"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),26288,489,27015,"0,018101055",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,77","15,29"
"low bq, bad alignment, many samples",UPN2_037,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),28217,969,29397,"0,0329625472",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"25,83","15,78"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),20343,395,20876,"0,0189212493",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"27,06","15,01"
"low bq, bad alignment, many samples",UPN2_052,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),24644,559,25388,"0,0220182764",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,69","14,87"
"low bq, bad alignment, many samples",UPN2_038,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),27191,899,28288,"0,0317802602",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"25,91","15,73"
"low bq, bad alignment, many samples",UPN2_039,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6950,212,7202,"0,0294362677",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"25,63","15,89"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),30060,618,30901,"0,0199993528",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,63","15,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),19006,408,19561,"0,0208578294",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,48","15,2"
"low bq, bad alignment, many samples",UPN2_007,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),28154,816,29160,"0,0279835391",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"25,82","15,11"
"low bq, bad alignment, many samples",UPN2_008,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),39443,1254,40986,"0,0305958132",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"25,11","15,1"
"low bq, bad alignment, many samples",UPN2_009,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),32701,1013,33911,"0,0298723128",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"25,28","15,02"
"low bq, bad alignment, many samples",UPN2_010,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),21802,695,22651,"0,0306829721",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"25,06","15,11"
"low bq, bad alignment, many samples",UPN2_011,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),24596,704,25467,"0,0276436172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"25,39","15,1"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),29723,623,30558,"0,0203874599",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,83","15,19"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),18772,404,19327,"0,0209033994",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,76","15,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_090,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),13948,171,14187,"0,0120532882",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,9","14,78"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),27390,584,28213,"0,0206996775",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,99","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),29158,590,29969,"0,0196870099",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"27,17","15,27"
"bad alignment, many artifacts, many samples",UPN2_059,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5495,339,5881,"0,0576432579",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,009",Damaging,"22,78","15,83"
"low bq, bad alignment, many samples",UPN2_012,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),13382,352,13856,"0,025404157",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"25,57","14,7"
"inspected, bad alignment, many artifacts, many samples",UPN2_060,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6510,351,6916,"0,0507518797",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,009",Damaging,"22,99","16,34"
"low bq, bad alignment, many samples",UPN2_040,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2724,94,2838,"0,0331219168",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,02","16,1"
"low bq, bad alignment, many samples",UPN2_013,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7585,223,7872,"0,028328252",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"25,31","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_091,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),16617,198,16878,"0,0117312478",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"27,02","15,2"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_092,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),10361,126,10538,"0,011956728",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,96","15,17"
"bad alignment, many artifacts, many samples",UPN2_061,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7228,473,7747,"0,0610558926",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,009",Damaging,"22,61","16,48"
"bad alignment, many artifacts, many samples",UPN2_062,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),10030,724,10859,"0,066672806",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,009",Damaging,"22,34","16,51"
"bad alignment, many artifacts, many samples",UPN2_063,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7659,538,8262,"0,065117405",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,009",Damaging,"22,68","16,3"
"bad alignment, many artifacts, many samples",UPN2_064,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6588,429,7081,"0,0605846632",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,009",Damaging,"22,84","16,42"
"bad alignment, many artifacts, many samples",UPN2_065,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3753,251,4036,"0,0621902874",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,009",Damaging,"23,05","16,48"
"low bq, bad alignment, many samples",UPN2_066,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2705,162,2885,"0,056152513",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"22,99","16,09"
"low bq, bad alignment, many samples",UPN2_067,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3285,177,3481,"0,0508474576",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"23,01","15,67"
"bad alignment, many artifacts, many samples",UPN2_068,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5161,341,5538,"0,0615745757",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,009",Damaging,"22,68","16,55"
"bad alignment, many artifacts, many samples",UPN2_069,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7996,521,8564,"0,0608360579",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,009",Damaging,"22,76","16,39"
"bad alignment, many artifacts, many samples",UPN2_070,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4882,319,5228,"0,0610175976",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,009",Damaging,"22,59","16,04"
"bad alignment, many artifacts, many samples",UPN2_071,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7319,480,7855,"0,0611075748",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,009",Damaging,"22,86","16,26"
"bad alignment, many artifacts, many samples",UPN2_072,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),9926,586,10596,"0,0553038883",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,009",Damaging,23,"16,39"
"bad alignment, many artifacts, many samples",UPN2_073,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5635,334,6022,"0,0554633012",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,009",Damaging,23,"16,47"
"low bq, bad alignment, many samples",UPN2_074,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2707,153,2882,"0,0530881332",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"23,46","15,87"
"bad alignment, many artifacts, many samples",UPN2_075,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),9845,544,10455,"0,0520325203",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,009",Damaging,"23,26","16,12"
"bad alignment, many artifacts, many samples",UPN2_076,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6568,470,7090,"0,0662905501",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,009",Damaging,"22,49","16,16"
"bad alignment, many artifacts, many samples",UPN2_077,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6151,394,6599,"0,0597060161",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,009",Damaging,"22,55","16,8"
"bad alignment, many artifacts, many samples",UPN2_078,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7967,545,8562,"0,063653352",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,009",Damaging,"22,44","16,58"
"bad alignment, many artifacts, many samples",UPN2_079,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6060,354,6461,"0,0547902801",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,009",Damaging,"23,03","16,6"
"bad alignment, many artifacts, many samples",UPN2_080,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),9840,633,10552,"0,0599886277",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,009",Damaging,"22,84",16
"bad alignment, many artifacts, many samples",UPN2_081,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),12621,750,13457,"0,0557330757",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,009",Damaging,"23,07","16,46"
"low bq, bad alignment, many samples",UPN2_082,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5336,319,5706,"0,0559060638",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"22,79","15,65"
"bad alignment, many artifacts, many samples",UPN2_083,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7702,528,8287,"0,0637142512",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,009",Damaging,"22,48","16,64"
"bad alignment, many artifacts, many samples",UPN2_084,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8275,534,8864,"0,0602436823",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,009",Damaging,"22,7","16,04"
"bad alignment, many artifacts, many samples",UPN2_085,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4203,268,4498,"0,0595820365",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,009",Damaging,"22,86","16,17"
"bad alignment, many artifacts, many samples",UPN2_086,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2860,223,3123,"0,0714056996",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,009",Damaging,"22,64","17,16"
"bad alignment, many artifacts, many samples",UPN2_087,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7662,453,8163,"0,0554943036",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,009",Damaging,"22,81","16,56"
"low bq, bad alignment, many samples",UPN2_088,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4973,264,5262,"0,0501710376",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"23,06","16,15"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_094,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),16069,232,16352,"0,0141878669",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,96","14,87"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_095,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),15975,230,16286,"0,0141225593",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,81","14,88"
"low freq, many artifacts, many samples",UPN2_096,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),16290,223,16597,"0,0134361632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,27,"15,54"
"low bq, low freq, many artifacts, many samples",UPN2_097,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),16768,233,17079,"0,0136424849",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"27,07","15,07"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_098,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),15673,179,15915,"0,011247251",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,94","14,8"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_099,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7883,89,8006,"0,0111166625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,74","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_100,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),10616,134,10802,"0,0124051102",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"27,34","14,81"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_101,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),14501,204,14780,"0,0138024357",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,59","14,71"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_102,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),14962,210,15232,"0,0137867647",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,59","15,09"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_103,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),12321,147,12510,"0,0117505995",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,6","15,42"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_104,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),16170,217,16450,"0,0131914894",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,77","14,71"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_105,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),12626,137,12817,"0,0106889288",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,88","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_106,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),20497,257,20846,"0,0123285043",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"27,08","14,86"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_107,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),25219,323,25694,"0,0125710283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,82","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_108,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),19161,229,19510,"0,0117375705",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"27,07","15,05"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_109,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),16613,248,16930,"0,0146485529",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,91","14,83"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_110,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),19813,239,20152,"0,011859865",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,9","14,55"
"low bq, bad alignment, low freq, many artifacts",UPN2_111,2,25505377,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu127Asp/c.381A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),17644,267,17982,"0,0148481815",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,9,Damaging,"26,75","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_090,2,25505378,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu127Ala/c.380A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7187,74,7298,"0,0101397643",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,3,Damaging,"27,82","14,55"
"low bq, bad alignment, many samples",UPN2_059,2,25505378,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu127Ala/c.380A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2931,103,3052,"0,0337483617",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,3,Damaging,"23,7",14
"low bq, bad alignment, many samples",UPN2_060,2,25505378,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu127Ala/c.380A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3418,124,3555,"0,0348804501",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,3,Damaging,"23,75","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_091,2,25505378,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu127Ala/c.380A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8582,88,8697,"0,0101184316",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,3,Damaging,"27,9","14,08"
"low bq, low freq, many artifacts, many samples",UPN2_092,2,25505378,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu127Ala/c.380A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5334,61,5427,"0,0112400958",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,3,Damaging,"27,68","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_093,2,25505378,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu127Ala/c.380A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6063,62,6156,"0,010071475",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,3,Damaging,"28,05","14,47"
"low bq, bad alignment, many samples",UPN2_061,2,25505378,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu127Ala/c.380A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3871,134,4029,"0,0332588732",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,3,Damaging,"23,43","14,54"
"low bq, bad alignment, many samples",UPN2_062,2,25505378,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu127Ala/c.380A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5403,196,5634,"0,0347887824",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,3,Damaging,"23,17","14,88"
"low bq, bad alignment, many samples",UPN2_063,2,25505378,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu127Ala/c.380A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4073,151,4249,"0,0355377736",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,3,Damaging,"23,54","14,57"
"low bq, bad alignment, many samples",UPN2_064,2,25505378,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu127Ala/c.380A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3486,139,3639,"0,038197307",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,3,Damaging,"23,55","14,86"
"low bq, bad alignment, many samples",UPN2_065,2,25505378,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu127Ala/c.380A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2011,68,2096,"0,0324427481",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,3,Damaging,"24,19","15,1"
"low bq, bad alignment, many samples",UPN2_066,2,25505378,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu127Ala/c.380A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),1420,48,1478,"0,0324763194",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,3,Damaging,"23,68","14,73"
"low bq, bad alignment, many samples",UPN2_067,2,25505378,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu127Ala/c.380A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),1737,48,1798,"0,0266963293",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,3,Damaging,"23,81","14,54"
"low bq, bad alignment, many samples",UPN2_068,2,25505378,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu127Ala/c.380A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2720,126,2859,"0,0440713536",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,3,Damaging,"23,53","14,59"
"low bq, bad alignment, many samples",UPN2_069,2,25505378,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu127Ala/c.380A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4280,150,4448,"0,0337230216",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,3,Damaging,"23,5","14,75"
"low bq, bad alignment, many samples",UPN2_070,2,25505378,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu127Ala/c.380A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2593,91,2700,"0,0337037037",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,3,Damaging,"23,35","14,98"
"low bq, bad alignment, many samples",UPN2_071,2,25505378,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu127Ala/c.380A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3866,165,4049,"0,0407508027",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,3,Damaging,"23,77","14,64"
"low bq, bad alignment, many samples",UPN2_072,2,25505378,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu127Ala/c.380A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5277,188,5485,"0,0342752963",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,3,Damaging,"24,05","14,52"
"low bq, bad alignment, many samples",UPN2_073,2,25505378,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu127Ala/c.380A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2961,119,3098,"0,0384118786",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,3,Damaging,"24,04","14,28"
"low bq, bad alignment, many samples",UPN2_074,2,25505378,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu127Ala/c.380A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),1414,47,1466,"0,0320600273",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,3,Damaging,"24,28","14,45"
"low bq, bad alignment, many samples",UPN2_075,2,25505378,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu127Ala/c.380A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5174,175,5379,"0,0325339282",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,3,Damaging,"23,7","14,36"
"low bq, bad alignment, many samples",UPN2_076,2,25505378,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu127Ala/c.380A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3541,123,3683,"0,0333966875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,3,Damaging,"23,37","14,89"
"low bq, bad alignment, many samples",UPN2_077,2,25505378,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu127Ala/c.380A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3286,120,3419,"0,0350979819",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,3,Damaging,"23,2","15,28"
"low bq, bad alignment, many samples",UPN2_078,2,25505378,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu127Ala/c.380A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4226,182,4434,"0,0410464592",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,3,Damaging,"23,1","14,91"
"low bq, bad alignment, many samples",UPN2_079,2,25505378,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu127Ala/c.380A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3197,120,3336,"0,035971223",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,3,Damaging,"23,88","14,54"
"low bq, bad alignment, many samples",UPN2_080,2,25505378,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu127Ala/c.380A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5232,177,5437,"0,0325547177",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,3,Damaging,"23,77","14,55"
"low bq, bad alignment, many samples",UPN2_081,2,25505378,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu127Ala/c.380A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6605,239,6894,"0,0346678271",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,3,Damaging,"23,97","14,38"
"low bq, bad alignment, many samples",UPN2_082,2,25505378,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu127Ala/c.380A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2817,107,2935,"0,0364565588",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,3,Damaging,"23,57","14,79"
"low bq, bad alignment, many samples",UPN2_083,2,25505378,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu127Ala/c.380A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4113,167,4301,"0,0388281795",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,3,Damaging,"23,38","14,78"
"low bq, bad alignment, many samples",UPN2_084,2,25505378,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu127Ala/c.380A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4372,181,4568,"0,0396234676",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,3,Damaging,"23,61","14,43"
"low bq, bad alignment, many samples",UPN2_085,2,25505378,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu127Ala/c.380A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2225,86,2328,"0,0369415808",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,3,Damaging,"23,58","14,44"
"low bq, bad alignment, many samples",UPN2_086,2,25505378,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu127Ala/c.380A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),1530,67,1616,"0,041460396",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,3,Damaging,"23,35","14,63"
"low bq, bad alignment, many samples",UPN2_087,2,25505378,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu127Ala/c.380A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4021,156,4194,"0,0371959943",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,3,Damaging,"23,67","14,48"
"low bq, bad alignment, many samples",UPN2_088,2,25505378,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu127Ala/c.380A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2592,99,2697,"0,0367074527",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,3,Damaging,"23,67","14,2"
"low bq, low freq, many artifacts, many samples",UPN2_097,2,25505378,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu127Ala/c.380A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8633,90,8744,"0,0102927722",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,3,Damaging,"27,97","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_099,2,25505378,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu127Ala/c.380A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4057,49,4117,"0,0119018703",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,3,Damaging,"27,25","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_101,2,25505378,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu127Ala/c.380A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7498,79,7598,"0,010397473",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,3,Damaging,"27,52","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_103,2,25505378,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu127Ala/c.380A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6343,68,6432,"0,0105721393",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,3,Damaging,"27,53","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_104,2,25505378,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu127Ala/c.380A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8319,87,8435,"0,0103141672",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,3,Damaging,"27,61","14,48"
"low bq, low freq, many artifacts",UPN2_106,2,25505378,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu127Ala/c.380A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),10527,111,10666,"0,0104069004",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,3,Damaging,"27,93","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_041,2,25505384,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu125Gln/c.374T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),19849,306,20263,"0,0151014164",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,36",Neutral,95,Tolerated,"32,25","16,41"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,25505384,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu125Gln/c.374T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),17178,242,17524,"0,0138096325",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,36",Neutral,95,Tolerated,"32,28","16,24"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,25505384,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu125Gln/c.374T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),11065,166,11308,"0,0146798727",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,36",Neutral,95,Tolerated,"32,33","17,33"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,25505384,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu125Gln/c.374T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),3029,50,3096,"0,0161498708",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,36",Neutral,95,Tolerated,"32,16","17,76"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,25505384,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu125Gln/c.374T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),15963,231,16307,"0,0141656957",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,36",Neutral,95,Tolerated,"32,3","16,28"
"low bq, low freq, many artifacts, many samples",UPN2_032,2,25505384,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu125Gln/c.374T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),3328,38,3382,"0,0112359551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,36",Neutral,95,Tolerated,"33,16","19,68"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,25505384,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu125Gln/c.374T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),13472,184,13717,"0,0134140118",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,36",Neutral,95,Tolerated,"32,34","16,31"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,25505384,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu125Gln/c.374T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),21360,281,21755,"0,0129165709",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,36",Neutral,95,Tolerated,"32,36","16,86"
"low bq, low freq, many artifacts, many samples",UPN2_048,2,25505384,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu125Gln/c.374T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),18441,240,18772,"0,0127849989",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,36",Neutral,95,Tolerated,"32,31","16,14"
"low bq, low freq, many artifacts, many samples",UPN2_036,2,25505384,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu125Gln/c.374T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),5332,71,5436,"0,0130610743",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,36",Neutral,95,Tolerated,"33,09","19,34"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,25505384,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu125Gln/c.374T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),14374,247,14704,"0,0167981502",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,36",Neutral,95,Tolerated,"32,39","18,38"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,25505384,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu125Gln/c.374T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),13236,165,13482,"0,0122385403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,36",Neutral,95,Tolerated,"32,27","17,07"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,25505384,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu125Gln/c.374T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),10214,155,10425,"0,0148681055",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,36",Neutral,95,Tolerated,"32,39","16,86"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,25505384,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu125Gln/c.374T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),12434,151,12649,"0,0119377026",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,36",Neutral,95,Tolerated,"32,32","17,62"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,25505384,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu125Gln/c.374T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),15127,202,15423,"0,0130973222",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,36",Neutral,95,Tolerated,"32,27","16,98"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,25505384,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu125Gln/c.374T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),9557,139,9758,"0,0142447223",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,36",Neutral,95,Tolerated,"32,2","17,73"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,25505384,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu125Gln/c.374T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),14952,179,15224,"0,0117577509",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,36",Neutral,95,Tolerated,"32,32","17,65"
"low bq, low freq, many artifacts, many samples",UPN2_056,2,25505384,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu125Gln/c.374T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),9466,114,9625,"0,0118441558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,36",Neutral,95,Tolerated,"32,22","16,96"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,25505384,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu125Gln/c.374T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),13800,173,14050,"0,0123131673",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,36",Neutral,95,Tolerated,"32,36","16,85"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,25505384,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu125Gln/c.374T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),14650,210,14937,"0,014059048",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,36",Neutral,95,Tolerated,"32,44","16,36"
"low bq, low freq, many artifacts",UPN2_064,2,25505384,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu125Gln/c.374T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),3484,37,3542,"0,0104460757",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,36",Neutral,95,Tolerated,"31,24","15,81"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_001,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4528,68,4606,"0,0147633521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"24,95","14,85"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_002,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6343,89,6457,"0,0137834908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"24,05","14,55"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_041,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),19690,441,20270,"0,0217562901",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"24,7","14,77"
"low bq, bad alignment, many samples",UPN2_089,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6755,216,7004,"0,0308395203",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"22,88","14,52"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),17095,340,17529,"0,0193964288",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"24,27","14,62"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_043,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),11020,220,11314,"0,0194449355",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"24,73","14,67"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_044,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3028,53,3097,"0,0171133355",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"24,72","14,13"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_029,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),9124,104,9268,"0,011221407",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"26,5","14,66"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_005,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),1836,33,1878,"0,017571885",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"24,36","14,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),15874,336,16318,"0,0205907587",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"24,44","14,77"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),13383,270,13718,"0,0196821694",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"24,38","14,48"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_033,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5877,65,5980,"0,0108695652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"26,87","14,4"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),21230,426,21763,"0,0195745072",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"24,69","14,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_048,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),18348,358,18784,"0,0190587734",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"24,75","14,53"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_006,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5126,76,5224,"0,0145482389",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"24,57","14,17"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),14371,276,14709,"0,018764022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"24,25","14,63"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),13170,244,13490,"0,0180874722",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"23,84","14,73"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),10171,193,10430,"0,0185043145",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"24,63","14,9"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),12334,261,12655,"0,0206242592",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"24,08","14,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),15038,316,15424,"0,0204875519",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"24,12","14,59"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),9518,195,9765,"0,019969278",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"23,95","14,55"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_007,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),14325,188,14571,"0,0129023403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"25,65","14,47"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_008,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),20116,287,20490,"0,0140068326",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"25,14","14,77"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_009,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),16664,215,16952,"0,0126828693",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"25,28","14,58"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_010,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),11159,140,11329,"0,0123576662",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"25,07","14,34"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_011,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),12535,156,12750,"0,0122352941",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"25,41","14,26"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),14844,292,15227,"0,0191764629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"24,1","14,63"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),9399,190,9632,"0,0197259136",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"24,22","14,61"
"low bq, bad alignment, many samples",UPN2_090,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6838,235,7103,"0,0330846121",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"22,58","14,48"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),13741,249,14059,"0,0177110748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"24,56","14,69"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_058,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),14570,285,14946,"0,0190686471",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"24,87","14,26"
"low bq, bad alignment, many samples",UPN2_059,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2643,281,2941,"0,0955457327",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"19,55","14,8"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_012,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6807,102,6949,"0,014678371",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"25,52","14,63"
"low bq, bad alignment, many samples",UPN2_060,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3125,308,3448,"0,0893271462",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"19,41","14,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_013,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3856,52,3925,"0,0132484076",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"25,07","14,35"
"low bq, bad alignment, many samples",UPN2_091,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8170,259,8457,"0,0306255173",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"22,73","14,34"
"low bq, bad alignment, many samples",UPN2_092,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5063,180,5274,"0,0341296928",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"22,17","14,52"
"low bq, bad alignment, many samples",UPN2_093,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5751,210,5989,"0,0350642845",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"22,56","14,34"
"low bq, bad alignment, many samples",UPN2_061,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3486,375,3869,"0,0969242698",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"19,37","15,43"
"low bq, bad alignment, many samples",UPN2_062,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4901,503,5431,"0,0926164611",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"18,93","14,67"
"low bq, bad alignment, many samples",UPN2_063,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3708,408,4144,"0,0984555985",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"19,07","14,49"
"low bq, bad alignment, many samples",UPN2_064,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3229,301,3544,"0,0849322799",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"19,23","14,53"
"low bq, bad alignment, many samples",UPN2_065,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),1843,168,2017,"0,0832920178",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"19,81","15,07"
"low bq, bad alignment, many samples",UPN2_066,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),1321,115,1441,"0,0798056905",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"19,65","14,42"
"low bq, bad alignment, many samples",UPN2_067,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),1589,137,1740,"0,0787356322",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"19,82","14,45"
"low bq, bad alignment, many samples",UPN2_068,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2495,266,2771,"0,0959942259",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"19,46","14,72"
"low bq, bad alignment, many samples",UPN2_069,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3920,373,4306,"0,0866233163",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"19,52","14,93"
"low bq, bad alignment, many samples",UPN2_070,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2359,240,2607,"0,0920598389",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"19,4","14,64"
"low bq, bad alignment, many samples",UPN2_071,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3594,325,3941,"0,0824663791",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"19,58","14,76"
"low bq, bad alignment, many samples",UPN2_072,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4872,432,5322,"0,0811724915",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"19,94","14,69"
"low bq, bad alignment, many samples",UPN2_073,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2726,273,3012,"0,0906374502",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"19,93","15,12"
"low bq, bad alignment, many samples",UPN2_074,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),1315,117,1439,"0,0813064628",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"19,43","15,09"
"low bq, bad alignment, many samples",UPN2_075,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4763,448,5229,"0,0856760375",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"19,74","14,67"
"low bq, bad alignment, many samples",UPN2_076,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3185,357,3555,"0,1004219409",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"19,22","14,66"
"low bq, bad alignment, many samples",UPN2_077,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3005,282,3303,"0,0853769301",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"19,37","14,63"
"low bq, bad alignment, many samples",UPN2_078,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3892,387,4296,"0,0900837989",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"18,89","14,63"
"low bq, bad alignment, many samples",UPN2_079,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2902,295,3229,"0,091359554",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"19,51","14,8"
"low bq, bad alignment, many samples",UPN2_080,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4817,448,5285,"0,0847682119",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"19,6","14,81"
"low bq, bad alignment, many samples",UPN2_081,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6100,581,6722,"0,0864326093",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"19,74","14,72"
"low bq, bad alignment, many samples",UPN2_082,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2601,238,2852,"0,0834502104",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"19,46","14,45"
"low bq, bad alignment, many samples",UPN2_083,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3734,382,4147,"0,0921147818",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"19,18","14,81"
"low bq, bad alignment, many samples",UPN2_084,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4035,381,4443,"0,0857528697",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"19,42","14,94"
"low bq, bad alignment, many samples",UPN2_085,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2043,193,2245,"0,0859688196",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"19,2","14,82"
"low bq, bad alignment, many samples",UPN2_086,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),1408,157,1569,"0,1000637349",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"19,43","14,66"
"low bq, bad alignment, many samples",UPN2_087,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3767,307,4092,"0,0750244379",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"19,69","14,54"
"low bq, bad alignment, many samples",UPN2_088,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2388,242,2635,"0,0918406072",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"19,43","14,95"
"low bq, bad alignment, many samples",UPN2_094,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7863,281,8176,"0,0343688845",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"22,3","14,34"
"low bq, bad alignment, many samples",UPN2_095,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7839,293,8160,"0,0359068627",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"22,25","14,4"
"low bq, bad alignment, many samples",UPN2_096,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7984,285,8309,"0,0343001565",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"22,75","14,63"
"low bq, bad alignment, many samples",UPN2_097,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8227,286,8543,"0,033477701",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"22,82","14,41"
"low bq, bad alignment, many samples",UPN2_098,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7671,271,7967,"0,0340153132",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"22,35","14,6"
"low bq, bad alignment, many samples",UPN2_099,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3885,110,4012,"0,0274177468",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"22,12","14,25"
"low bq, bad alignment, many samples",UPN2_100,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5204,182,5406,"0,0336662967",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"22,71","14,43"
"low bq, bad alignment, many samples",UPN2_101,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7124,248,7397,"0,0335271056",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"22,08","14,38"
"low bq, bad alignment, many samples",UPN2_102,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7319,274,7625,"0,0359344262",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"21,87","14,27"
"low bq, bad alignment, many samples",UPN2_103,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6014,235,6276,"0,037444232",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"21,95","14,4"
"low bq, bad alignment, many samples",UPN2_104,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7912,297,8239,"0,0360480641",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"22,49","14,52"
"low bq, bad alignment, many samples",UPN2_105,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6168,209,6411,"0,0326002184",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"22,31","14,52"
"low bq, bad alignment, many samples",UPN2_106,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),10018,382,10433,"0,0366145883",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"22,88","14,78"
"low bq, bad alignment, many samples",UPN2_107,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),12371,449,12857,"0,0349226103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"22,43","14,63"
"low bq, bad alignment, many samples",UPN2_108,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),9400,336,9767,"0,0344015563",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"22,9","14,61"
"low bq, bad alignment, many samples",UPN2_109,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8146,278,8465,"0,0328411105",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"22,72","14,64"
"low bq, bad alignment, many samples",UPN2_110,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),9673,375,10093,"0,0371544635",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"22,61","14,47"
"low bq, bad alignment",UPN2_111,2,25505388,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr124Pro/c.370A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8666,295,9002,"0,0327704954",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,6,Damaging,"22,56","14,58"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_059,2,25505390,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu123Ala/c.368A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2865,57,2941,"0,0193811629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,78,Tolerated,"25,64","14,56"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_060,2,25505390,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu123Ala/c.368A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3369,62,3448,"0,0179814385",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,78,Tolerated,"25,45","14,66"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,2,25505390,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu123Ala/c.368A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3765,85,3869,"0,0219695012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,78,Tolerated,"25,35","14,62"
"low bq, bad alignment, many samples",UPN2_062,2,25505390,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu123Ala/c.368A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5261,139,5432,"0,0255891016",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,78,Tolerated,"25,13","14,7"
"low bq, bad alignment, many samples",UPN2_063,2,25505390,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu123Ala/c.368A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4016,99,4147,"0,023872679",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,78,Tolerated,"25,46","14,57"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,2,25505390,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu123Ala/c.368A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3441,75,3545,"0,0211565585",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,78,Tolerated,"25,67","14,19"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_065,2,25505390,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu123Ala/c.368A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),1975,37,2018,"0,0183349851",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,78,Tolerated,"26,3","14,86"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_066,2,25505390,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu123Ala/c.368A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),1411,20,1441,"0,0138792505",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,78,Tolerated,"25,71","14,65"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_067,2,25505390,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu123Ala/c.368A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),1706,30,1741,"0,0172314762",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,78,Tolerated,"26,22","14,7"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_068,2,25505390,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu123Ala/c.368A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2718,46,2772,"0,0165945166",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,78,Tolerated,"25,8","14,91"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_069,2,25505390,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu123Ala/c.368A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4205,92,4306,"0,0213655365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,78,Tolerated,"25,95","14,74"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_070,2,25505390,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu123Ala/c.368A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2546,46,2608,"0,0176380368",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,78,Tolerated,"25,52","14,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,2,25505390,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu123Ala/c.368A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3851,70,3942,"0,0177574835",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,78,Tolerated,"25,86","15,09"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,2,25505390,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu123Ala/c.368A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5203,95,5324,"0,0178437265",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,78,Tolerated,"26,12","14,44"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,2,25505390,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu123Ala/c.368A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2946,49,3013,"0,0162628609",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,78,Tolerated,"26,37","15,86"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,2,25505390,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu123Ala/c.368A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),1399,31,1439,"0,021542738",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,78,Tolerated,"25,76","14,87"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_075,2,25505390,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu123Ala/c.368A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5124,84,5233,"0,0160519778",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,78,Tolerated,"26,03","14,95"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,2,25505390,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu123Ala/c.368A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3466,77,3555,"0,0216596343",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,78,Tolerated,"25,32","14,18"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,2,25505390,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu123Ala/c.368A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3229,68,3304,"0,0205811138",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,78,Tolerated,"25,42",15
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,2,25505390,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu123Ala/c.368A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4191,89,4297,"0,0207121247",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,78,Tolerated,"25,16","14,3"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_079,2,25505390,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu123Ala/c.368A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3153,53,3229,"0,0164137504",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,78,Tolerated,"25,82","15,3"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,2,25505390,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu123Ala/c.368A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5180,81,5286,"0,015323496",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,78,Tolerated,"25,87","14,78"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_081,2,25505390,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu123Ala/c.368A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6581,110,6723,"0,0163617433",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,78,Tolerated,"26,1","14,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_082,2,25505390,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu123Ala/c.368A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2787,51,2852,"0,0178821879",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,78,Tolerated,"25,73","14,41"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,2,25505390,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu123Ala/c.368A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4042,80,4148,"0,0192864031",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,78,Tolerated,"25,34","14,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,2,25505390,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu123Ala/c.368A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4338,77,4443,"0,0173306325",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,78,Tolerated,"25,66","14,27"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_085,2,25505390,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu123Ala/c.368A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2199,37,2246,"0,0164737311",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,78,Tolerated,"25,72","16,11"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,2,25505390,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu123Ala/c.368A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),1528,29,1569,"0,0184831103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,78,Tolerated,"25,46","14,48"
"low bq, bad alignment, many samples",UPN2_087,2,25505390,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu123Ala/c.368A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3985,92,4092,"0,0224828935",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,78,Tolerated,"25,85","14,85"
"low bq, bad alignment, low freq, many artifacts",UPN2_088,2,25505390,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu123Ala/c.368A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2581,40,2635,"0,0151802657",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,78,Tolerated,"25,97","14,55"
"low bq, bad alignment, many samples",UPN2_001,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4456,130,4612,"0,0281873374",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"22,3","14,27"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_014,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7409,143,7580,"0,0188654354",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"22,59","14,46"
"low bq, bad alignment, many samples",UPN2_015,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),10863,251,11171,"0,0224688927",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"22,78","14,25"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_016,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4529,73,4620,"0,0158008658",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"22,76","14,3"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_017,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3438,72,3520,"0,0204545455",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"22,59","14,4"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_018,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5025,103,5151,"0,0199961173",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"22,97","14,07"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_019,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5568,103,5691,"0,0180987524",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"22,97","14,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_020,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5294,98,5419,"0,0180845174",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"22,97","14,07"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_021,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5585,109,5712,"0,0190826331",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"23,1","14,37"
"low bq, bad alignment, many samples",UPN2_002,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6231,208,6460,"0,0321981424",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"22,02","14,25"
"low bq, bad alignment, many samples",UPN2_003,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),1095,49,1149,"0,0426457789",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"22,46","14,71"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_022,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7160,140,7342,"0,0190683737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"22,71","14,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_023,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8707,177,8929,"0,0198230485",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"22,63","14,37"
"low bq, bad alignment, many samples",UPN2_041,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),19412,781,20306,"0,0384615385",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"21,98","14,36"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_024,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4050,78,4154,"0,0187770823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"22,83","14,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_025,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8651,177,8869,"0,0199571541",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"22,86","14,64"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_026,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8574,157,8779,"0,0178835858",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"22,73","14,42"
"low bq, bad alignment, many samples",UPN2_004,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),1040,36,1080,"0,0333333333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"21,63","14,56"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_027,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),9357,192,9593,"0,020014594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"22,6","14,38"
"low bq, bad alignment, many samples",UPN2_089,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6665,312,7005,"0,0445396146",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"21,58","14,77"
"low bq, bad alignment, many samples",UPN2_042,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),16719,757,17553,"0,0431265311",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"21,7","14,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_028,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7175,158,7376,"0,0214208243",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"22,65","14,23"
"low bq, bad alignment, many samples",UPN2_043,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),10824,442,11331,"0,0390080311",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"22,04","14,32"
"low bq, bad alignment, many samples",UPN2_044,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2952,134,3103,"0,0431840155",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"21,63","14,24"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_029,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),9047,185,9271,"0,0199546974",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"22,84","14,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_030,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8929,172,9143,"0,0188122061",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"22,79","14,37"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_031,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5430,114,5573,"0,0204557689",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"22,85","14,06"
"low bq, bad alignment, many samples",UPN2_005,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),1825,53,1882,"0,0281615303",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"21,89","14,55"
"low bq, bad alignment, many samples",UPN2_045,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),15605,649,16339,"0,0397209132",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"21,84","14,6"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_032,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3302,66,3384,"0,0195035461",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"22,9",14
"low bq, bad alignment, many samples",UPN2_046,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),13109,562,13731,"0,0409292841",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"21,7","14,53"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_033,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5837,118,5985,"0,0197159566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"22,64","14,17"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_034,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2601,44,2657,"0,0165600301",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"22,84","14,3"
"low bq, bad alignment, many samples",UPN2_047,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),20812,844,21793,"0,0387280319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"21,84","14,49"
"low bq, bad alignment, many samples",UPN2_048,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),18010,716,18808,"0,0380689068",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"22,06","14,51"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_035,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6122,122,6266,"0,0194701564",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"22,81","14,11"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_036,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5328,99,5440,"0,0181985294",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"22,44","14,4"
"low bq, bad alignment, many samples",UPN2_006,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5051,147,5232,"0,0280963303",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"22,19","14,2"
"low bq, bad alignment, many samples",UPN2_049,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),14071,585,14733,"0,0397067807",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"21,59","14,41"
"low bq, bad alignment, many samples",UPN2_050,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),12915,527,13507,"0,0390168061",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"21,68","14,63"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_037,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),14343,284,14702,"0,0193170997",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"22,68","14,6"
"low bq, bad alignment, many samples",UPN2_051,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),9981,411,10446,"0,0393452039",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"21,77","14,31"
"low bq, bad alignment, many samples",UPN2_052,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),12098,523,12671,"0,0412753532",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"21,7","14,59"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_038,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),13816,283,14180,"0,0199576869",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"22,73","14,21"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_039,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3528,70,3617,"0,019353055",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"22,58","14,31"
"low bq, bad alignment, many samples",UPN2_053,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),14711,630,15447,"0,0407846184",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"21,64","14,6"
"low bq, bad alignment, many samples",UPN2_054,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),9313,412,9777,"0,0421397157",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"21,38","14,47"
"low bq, bad alignment, many samples",UPN2_007,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),14099,425,14584,"0,029141525",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"22,76","14,34"
"low bq, bad alignment, many samples",UPN2_008,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),19816,616,20524,"0,0300136426",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"22,57","14,3"
"low bq, bad alignment, many samples",UPN2_009,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),16374,513,16963,"0,030242292",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"22,59","14,49"
"low bq, bad alignment, many samples",UPN2_010,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),10938,355,11336,"0,0313161609",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"22,57","14,5"
"low bq, bad alignment, many samples",UPN2_011,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),12337,385,12764,"0,0301629583",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"22,58","14,41"
"low bq, bad alignment, many samples",UPN2_055,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),14587,580,15246,"0,0380427653",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"21,64","14,37"
"low bq, bad alignment, many samples",UPN2_056,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),9232,358,9640,"0,0371369295",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"21,72","14,34"
"low bq, bad alignment, many samples",UPN2_090,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6741,338,7107,"0,0475587449",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"21,53","14,94"
"low bq, bad alignment, many samples",UPN2_057,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),13408,578,14074,"0,0410686372",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"21,73","14,35"
"low bq, bad alignment, many samples",UPN2_058,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),14287,602,14963,"0,0402325737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"21,77","14,4"
"low bq, bad alignment, many samples",UPN2_059,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2541,388,2943,"0,1318382603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"18,79","14,8"
"low bq, bad alignment, many samples",UPN2_012,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6715,215,6955,"0,0309130122",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"22,71","14,12"
"low bq, bad alignment, many samples",UPN2_060,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2981,454,3453,"0,1314798726",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"18,82","14,84"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_040,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),1402,28,1434,"0,019525802",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"22,48",14
"low bq, bad alignment, many samples",UPN2_013,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3784,121,3928,"0,0308044807",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"22,72","14,54"
"low bq, bad alignment, many samples",UPN2_091,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8032,406,8463,"0,0479735318",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"21,65","14,72"
"low bq, bad alignment, many samples",UPN2_092,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5037,235,5280,"0,0445075758",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"21,33","14,89"
"low bq, bad alignment, many samples",UPN2_093,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5672,306,5995,"0,0510425354",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"21,67","14,7"
"low bq, bad alignment, many samples",UPN2_061,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3320,535,3878,"0,1379577102",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"18,82","14,77"
"low bq, bad alignment, many samples",UPN2_062,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4639,775,5443,"0,1423847143",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"18,72","14,86"
"low bq, bad alignment, many samples",UPN2_063,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3570,553,4148,"0,1333172613",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"18,59","14,89"
"low bq, bad alignment, many samples",UPN2_064,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3055,481,3549,"0,1355311355",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"18,84","14,76"
"low bq, bad alignment, many samples",UPN2_065,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),1758,254,2021,"0,1256803563",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"19,32","14,73"
"low bq, bad alignment, many samples",UPN2_066,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),1243,192,1444,"0,1329639889",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"18,95","14,41"
"low bq, bad alignment, many samples",UPN2_067,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),1514,225,1747,"0,1287922152",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"18,79","14,56"
"low bq, bad alignment, many samples",UPN2_068,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2431,338,2784,"0,121408046",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"18,94","15,32"
"low bq, bad alignment, many samples",UPN2_069,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3739,557,4313,"0,129144447",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"18,6","14,79"
"low bq, bad alignment, many samples",UPN2_070,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2237,372,2618,"0,1420932009",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"18,91","14,98"
"low bq, bad alignment, many samples",UPN2_071,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3461,472,3948,"0,1195542047",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"18,85","15,17"
"low bq, bad alignment, many samples",UPN2_072,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4681,635,5334,"0,119047619",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"18,99","14,83"
"low bq, bad alignment, many samples",UPN2_073,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2607,400,3018,"0,1325381047",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"18,82","14,86"
"low bq, bad alignment, many samples",UPN2_074,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),1263,175,1440,"0,1215277778",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"18,95","15,29"
"low bq, bad alignment, many samples",UPN2_075,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4568,649,5241,"0,1238313299",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"18,95","14,95"
"low bq, bad alignment, many samples",UPN2_076,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3072,484,3566,"0,135726304",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"18,52","14,84"
"low bq, bad alignment, many samples",UPN2_077,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2870,425,3311,"0,1283600121",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"18,62","14,65"
"low bq, bad alignment, many samples",UPN2_078,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3740,554,4307,"0,1286278152",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"18,39","14,62"
"low bq, bad alignment, many samples",UPN2_079,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2804,419,3235,"0,1295208655",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"18,65","14,99"
"low bq, bad alignment, many samples",UPN2_080,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4609,667,5289,"0,126110796",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"18,85","14,88"
"low bq, bad alignment, many samples",UPN2_081,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5880,835,6741,"0,1238688622",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"18,94","14,9"
"low bq, bad alignment, many samples",UPN2_082,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2465,376,2859,"0,1315145156",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"19,01","14,88"
"low bq, bad alignment, many samples",UPN2_083,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3608,523,4157,"0,1258118836",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"18,64","14,97"
"low bq, bad alignment, many samples",UPN2_084,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3863,577,4454,"0,1295464751",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"18,97","14,89"
"low bq, bad alignment, many samples",UPN2_085,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),1959,284,2254,"0,1259982254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"18,73","15,24"
"low bq, bad alignment, many samples",UPN2_086,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),1323,243,1571,"0,1546785487",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"18,74","14,68"
"low bq, bad alignment, many samples",UPN2_087,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3543,533,4096,"0,1301269531",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"18,93","14,81"
"low bq, bad alignment, many samples",UPN2_088,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2327,307,2639,"0,1163319439",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"18,69","14,84"
"low bq, bad alignment, many samples",UPN2_094,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7751,407,8187,"0,0497129596",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"21,33","14,71"
"low bq, bad alignment, many samples",UPN2_095,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7733,407,8173,"0,0497981157",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"21,38","14,75"
"low bq, bad alignment, many samples",UPN2_096,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7918,373,8323,"0,0448155713",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"21,52","14,42"
"low bq, bad alignment, many samples",UPN2_097,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8111,410,8553,"0,0479363966",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"21,63","14,61"
"low bq, bad alignment, many samples",UPN2_098,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7574,371,7976,"0,0465145436",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"21,46","14,54"
"low bq, bad alignment, many samples",UPN2_099,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3808,195,4015,"0,0485678705",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"21,44","14,47"
"low bq, bad alignment, many samples",UPN2_100,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5159,233,5411,"0,0430604325",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"21,62","14,42"
"low bq, bad alignment, many samples",UPN2_101,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7030,348,7403,"0,0470079697",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"21,22","14,58"
"low bq, bad alignment, many samples",UPN2_102,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7200,407,7632,"0,0533280922",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"21,2","14,58"
"low bq, bad alignment, many samples",UPN2_103,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5961,301,6280,"0,0479299363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"21,32","14,59"
"low bq, bad alignment, many samples",UPN2_104,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7764,452,8246,"0,0548144555",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"21,19","14,47"
"low bq, bad alignment, many samples",UPN2_105,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6114,290,6419,"0,0451783767",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"21,39","14,52"
"low bq, bad alignment, many samples",UPN2_106,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),9863,530,10439,"0,0507711467",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"21,63","14,62"
"low bq, bad alignment, many samples",UPN2_107,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),12191,642,12867,"0,0498950804",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"21,44","14,47"
"low bq, bad alignment, many samples",UPN2_108,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),9260,492,9780,"0,0503067485",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"21,54","14,57"
"low bq, bad alignment, many samples",UPN2_109,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8068,381,8477,"0,0449451457",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"21,54","14,54"
"low bq, bad alignment, many samples",UPN2_110,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),9637,425,10100,"0,0420792079",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"21,51","14,62"
"low bq, bad alignment",UPN2_111,2,25505402,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu119Ala/c.356A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8536,434,9010,"0,0481687014",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,14,Damaging,"21,49","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,25505426,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys111Thr/c.332A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),1999,21,2028,"0,0103550296",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,271,Tolerated,"29,65","15,9"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25505426,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys111Thr/c.332A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6652,72,6761,"0,0106493122",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,271,Tolerated,"29,79","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,25505427,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys111Gln/c.331A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2900,41,2956,"0,0138700947",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,41",Neutral,7,Damaging,"27,73","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,25505427,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys111Gln/c.331A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3826,49,3887,"0,012606123",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,41",Neutral,7,Damaging,"27,4","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,25505427,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys111Gln/c.331A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5400,57,5466,"0,010428101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,41",Neutral,7,Damaging,"27,78","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,25505427,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys111Gln/c.331A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4095,50,4164,"0,0120076849",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,41",Neutral,7,Damaging,"27,79","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,25505427,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys111Gln/c.331A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),1992,29,2028,"0,0142998028",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,41",Neutral,7,Damaging,"27,69",14
"low bq, low freq, many artifacts, many samples",UPN2_067,2,25505427,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys111Gln/c.331A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),1728,22,1751,"0,012564249",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,41",Neutral,7,Damaging,"28,22",14
"low bq, low freq, many artifacts, many samples",UPN2_068,2,25505427,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys111Gln/c.331A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2755,32,2796,"0,0114449213",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,41",Neutral,7,Damaging,"27,54",14
"low bq, low freq, many artifacts, many samples",UPN2_069,2,25505427,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys111Gln/c.331A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4266,50,4334,"0,0115366867",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,41",Neutral,7,Damaging,"27,7",14
"low bq, low freq, many artifacts, many samples",UPN2_070,2,25505427,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys111Gln/c.331A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2584,28,2628,"0,0106544901",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,41",Neutral,7,Damaging,"27,89","15,57"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,25505427,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys111Gln/c.331A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5275,54,5349,"0,0100953449",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,41",Neutral,7,Damaging,"27,83","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,25505427,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys111Gln/c.331A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3528,36,3581,"0,0100530578",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,41",Neutral,7,Damaging,"27,22",14
"low bq, low freq, many artifacts, many samples",UPN2_077,2,25505427,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys111Gln/c.331A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3281,36,3332,"0,0108043217",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,41",Neutral,7,Damaging,"27,4","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,25505427,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys111Gln/c.331A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4255,51,4325,"0,0117919075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,41",Neutral,7,Damaging,"27,68","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,25505427,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys111Gln/c.331A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3204,37,3254,"0,0113706208",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,41",Neutral,7,Damaging,"27,89","16,46"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,25505427,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys111Gln/c.331A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5227,63,5308,"0,0118688772",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,41",Neutral,7,Damaging,"27,65",14
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25505427,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys111Gln/c.331A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6663,74,6761,"0,0109451265",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,41",Neutral,7,Damaging,"27,87","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,25505427,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys111Gln/c.331A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2833,34,2876,"0,011821975",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,41",Neutral,7,Damaging,"27,79",14
"low bq, low freq, many artifacts, many samples",UPN2_083,2,25505427,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys111Gln/c.331A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4117,49,4176,"0,0117337165",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,41",Neutral,7,Damaging,"27,4","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,25505427,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys111Gln/c.331A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4399,53,4471,"0,0118541713",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,41",Neutral,7,Damaging,"27,85","14,13"
"low bq, low freq, many artifacts",UPN2_085,2,25505427,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys111Gln/c.331A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2219,30,2261,"0,0132684653",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,41",Neutral,7,Damaging,"27,67","14,23"
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_036,2,25505430,G,GC,frameshift_variant(HIGH||ggg/gggG|p.Gln110fs/c.327dupG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|GC),5433,116,5448,"0,0212922173",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,34",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_039,2,25505430,G,GC,frameshift_variant(HIGH||ggg/gggG|p.Gln110fs/c.327dupG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|GC),3620,85,3624,"0,0234547461",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,36",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_040,2,25505430,G,GC,frameshift_variant(HIGH||ggg/gggG|p.Gln110fs/c.327dupG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|GC),1431,49,1437,"0,034098817",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,42",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_088,2,25505430,G,GC,frameshift_variant(HIGH||ggg/gggG|p.Gln110fs/c.327dupG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|GC),2642,27,2653,"0,0101771579",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,61",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_014,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7442,115,7593,"0,0151455288",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,89",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_015,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),10993,153,11186,"0,0136778116",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,94",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_016,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4527,80,4625,"0,0172972973",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,81",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_017,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3454,53,3524,"0,0150397276",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,07",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_018,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5061,71,5158,"0,0137650252",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,89",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_019,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5602,72,5695,"0,012642669",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,01",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_020,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5336,70,5426,"0,0129008478",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,94",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_021,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5628,74,5722,"0,0129325411",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,97",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_002,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6366,85,6473,"0,0131314692",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,87",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_022,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7237,89,7354,"0,0121022573",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,92",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_023,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8783,133,8943,"0,0148719669",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,95",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_041,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),19921,293,20337,"0,014407238",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,13",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_024,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4082,60,4159,"0,0144265448",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,03",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_025,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8741,112,8884,"0,0126069338",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,93",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_026,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8653,112,8795,"0,0127345082",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,99",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_027,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),9449,113,9607,"0,0117622567",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,02",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_089,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6906,83,7023,"0,0118183113",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,82",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_042,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),17230,241,17592,"0,0136994088",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,28",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_028,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7282,94,7406,"0,0126924116",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,97",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_043,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),11159,159,11402,"0,0139449219",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,24",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_044,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3055,36,3109,"0,0115792859",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,2",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_029,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),9157,118,9296,"0,0126936317",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,01",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_030,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),9010,112,9163,"0,012223071",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,94",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_031,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5470,75,5580,"0,0134408602",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,93",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_005,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),1859,20,1888,"0,0105932203",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,82",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_045,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),16040,242,16389,"0,0147660016",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,19",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_032,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3327,47,3389,"0,0138683978",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,99",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_046,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),13451,232,13776,"0,0168408827",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,35",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_033,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5894,75,5990,"0,0125208681",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,87",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_034,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2623,29,2662,"0,0108940646",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,96",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_047,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),21347,351,21842,"0,016069957",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,22",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_048,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),18479,256,18856,"0,0135765804",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,21",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_035,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6146,105,6281,"0,0167170833",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,89",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_036,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5345,82,5449,"0,0150486328",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,94",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_006,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5148,75,5242,"0,0143075162",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,76",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_049,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),14476,204,14772,"0,0138099106",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,25",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_050,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),13270,216,13547,"0,0159444896",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,23",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_037,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),14447,205,14717,"0,0139294693",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,94",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_051,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),10248,161,10480,"0,0153625954",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,23",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_052,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),12447,184,12707,"0,0144802078",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,24",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_038,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),13937,208,14199,"0,0146489189",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,91",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_039,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3557,51,3624,"0,0140728477",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,94",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_053,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),15205,204,15496,"0,0131646877",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,26",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_054,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),9602,153,9810,"0,0155963303",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,25",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_007,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),14378,172,14610,"0,0117727584",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,78",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_008,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),20258,220,20561,"0,0106998687",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,76",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_009,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),16746,207,17029,"0,0121557343",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,85",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_011,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),12620,147,12813,"0,011472723",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,78",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_055,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),14988,216,15280,"0,0141361257",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,23",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_056,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),9495,115,9672,"0,0118899917",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,22",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_090,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7019,79,7124,"0,0110892757",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,71",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_057,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),13786,212,14112,"0,0150226757",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,22",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_058,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),14731,202,15002,"0,0134648714",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,25",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_059,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2909,32,2956,"0,0108254398",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,26",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_012,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6830,101,6964,"0,0145031591",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,89",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_060,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3398,49,3459,"0,0141659439",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,22",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_040,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),1408,24,1437,"0,0167014614",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,94",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_013,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3876,43,3938,"0,0109192483",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,71",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_091,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8368,86,8485,"0,0101355333",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,62",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_092,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5206,71,5297,"0,0134038135",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,78",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_093,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5912,84,6015,"0,0139650873",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,63",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_061,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3793,69,3887,"0,0177514793",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,33",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_062,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5371,72,5469,"0,0131651125",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,21",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_063,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4090,49,4166,"0,0117618819",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,32",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_064,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3490,62,3572,"0,0173572228",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,14",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_065,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),1993,21,2029,"0,0103499261",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,12",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_066,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),1419,22,1452,"0,0151515152",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,93",NA
"low freq, many artifacts",UPN2_068,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2757,30,2796,"0,0107296137",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,21",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_069,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4251,50,4334,"0,0115366867",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,18",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_070,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2588,27,2630,"0,0102661597",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,19",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_071,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3897,46,3960,"0,0116161616",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,28",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_072,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5264,56,5349,"0,0104692466",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,24",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_075,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5163,54,5256,"0,0102739726",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,14",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_076,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3522,37,3582,"0,0103294249",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,17",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_077,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3281,34,3335,"0,0101949025",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,12",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_078,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4249,55,4328,"0,0127079482",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,3",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_079,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3194,36,3256,"0,0110565111",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,16",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_080,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5202,73,5307,"0,0137554174",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,17",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_081,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6627,101,6764,"0,0149319929",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,17",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_082,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2819,36,2875,"0,0125217391",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,03",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_083,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4106,53,4180,"0,0126794258",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,35",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_084,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4383,64,4471,"0,014314471",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,2",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_085,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2223,26,2261,"0,0114993366",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,13",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_087,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),4022,63,4113,"0,0153172867",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,23",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_088,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),2605,35,2654,"0,0131876413",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,2",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_094,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8073,104,8204,"0,0126767431",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,77",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_095,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8051,106,8189,"0,0129441934",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,69",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_096,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8194,120,8340,"0,0143884892",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,66",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_097,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8453,92,8577,"0,0107263612",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,75",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_098,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7840,112,7991,"0,0140157677",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,69",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_099,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3955,56,4026,"0,0139095877",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,77",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_100,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),5322,81,5421,"0,0149418926",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,66",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_101,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7315,79,7419,"0,0106483354",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,8",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_102,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),7522,103,7658,"0,0134499869",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,75",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_103,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6175,86,6284,"0,0136855506",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,71",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_104,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8146,89,8264,"0,0107696031",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,71",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_105,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),6332,73,6434,"0,0113459745",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,68",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_106,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),10300,126,10460,"0,0120458891",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,74",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_107,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),12673,179,12889,"0,0138878113",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,73",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_108,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),9638,137,9807,"0,0139696135",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,65",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_109,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8362,118,8503,"0,013877455",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,71",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_110,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),9955,128,10118,"0,0126507215",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,74",NA
"many samples, ins and del, homopolymer 6C, low freq, no database",UPN2_111,2,25505430,GC,G,frameshift_variant(HIGH||ggg/|p.Gln110fs/c.327delG|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),8903,101,9034,"0,0111799867",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,78",NA
"low freq, many artifacts",UPN2_066,2,25505479,CA,C,frameshift_variant(HIGH||ttg/|p.Leu93fs/c.278delT|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),1435,21,1467,"0,0143149284",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,88",NA
"low freq, many artifacts, many samples",UPN2_001,2,25505498,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu87Arg/c.260T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),6722,96,6842,"0,0140309851",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,248,Tolerated,"32,93","31,89"
"low freq, many artifacts, many samples",UPN2_014,2,25505498,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu87Arg/c.260T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),11554,131,11749,"0,0111498851",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,248,Tolerated,"33,05","31,36"
"low freq, many artifacts, many samples",UPN2_017,2,25505498,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu87Arg/c.260T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),5443,72,5534,"0,0130104807",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,248,Tolerated,"33,12","31,75"
"low freq, many artifacts, many samples",UPN2_018,2,25505498,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu87Arg/c.260T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),7939,85,8060,"0,0105459057",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,248,Tolerated,"33,12","31,66"
"low freq, many artifacts, many samples",UPN2_020,2,25505498,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu87Arg/c.260T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),8279,101,8417,"0,0119995248",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,"0,248",Tolerated,"33,07","31,57"
"low freq, many artifacts, many samples",UPN2_021,2,25505498,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu87Arg/c.260T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),9074,107,9228,"0,0115951452",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,"0,248",Tolerated,"33,15","31,46"
"low freq, many artifacts, many samples",UPN2_002,2,25505498,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu87Arg/c.260T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),9287,139,9466,"0,0146841327",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,248,Tolerated,"32,94","31,66"
"low freq, many artifacts, many samples",UPN2_022,2,25505498,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu87Arg/c.260T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),10815,111,10973,"0,0101157386",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,"0,248",Tolerated,"32,98","31,84"
"low freq, many artifacts, many samples",UPN2_023,2,25505498,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu87Arg/c.260T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),13243,140,13441,"0,0104158917",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,"0,248",Tolerated,"32,98","31,38"
"low freq, many artifacts, many samples",UPN2_027,2,25505498,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu87Arg/c.260T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),13714,180,13977,"0,0128783001",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,248,Tolerated,"32,93","31,48"
"low freq, many artifacts, many samples",UPN2_028,2,25505498,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu87Arg/c.260T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),10402,107,10569,"0,0101239474",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,248,Tolerated,"32,87","31,22"
"low freq, many artifacts, many samples",UPN2_029,2,25505498,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu87Arg/c.260T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),13221,162,13473,"0,0120240481",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,"0,248",Tolerated,"32,91","31,78"
"low freq, many artifacts, many samples",UPN2_005,2,25505498,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu87Arg/c.260T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),2634,34,2680,"0,0126865672",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,248,Tolerated,"32,8",32
"low freq, many artifacts, many samples",UPN2_034,2,25505498,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu87Arg/c.260T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),3693,45,3755,"0,0119840213",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,248,Tolerated,"32,83","30,96"
"low freq, many artifacts, many samples",UPN2_006,2,25505498,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu87Arg/c.260T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),6938,123,7087,"0,0173557217",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,248,Tolerated,"32,66","31,71"
"low freq, many artifacts, many samples",UPN2_059,2,25505498,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu87Arg/c.260T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),2926,45,2980,"0,0151006711",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,248,Tolerated,"31,7","31,51"
"low freq, many artifacts, many samples",UPN2_060,2,25505498,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu87Arg/c.260T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),3385,61,3459,"0,0176351547",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,248,Tolerated,"31,67","31,46"
many samples,UPN2_061,2,25505498,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu87Arg/c.260T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),3786,92,3898,"0,0236018471",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,248,Tolerated,"31,67","31,49"
many samples,UPN2_062,2,25505498,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu87Arg/c.260T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),5411,123,5554,"0,0221462009",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,248,Tolerated,"31,72","31,34"
many samples,UPN2_063,2,25505498,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu87Arg/c.260T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),4072,101,4185,"0,0241338112",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,248,Tolerated,"31,66","31,45"
many samples,UPN2_064,2,25505498,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu87Arg/c.260T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),3513,94,3622,"0,0259525124",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,248,Tolerated,"31,67","31,81"
many samples,UPN2_065,2,25505498,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu87Arg/c.260T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),1975,46,2033,"0,0226266601",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,248,Tolerated,"31,66","31,61"
many samples,UPN2_066,2,25505498,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu87Arg/c.260T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),1417,39,1464,"0,0266393443",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,248,Tolerated,"31,62","30,69"
"low freq, many artifacts, many samples",UPN2_067,2,25505498,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu87Arg/c.260T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),1726,29,1762,"0,0164585698",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,248,Tolerated,"31,7","31,24"
"low freq, many artifacts, many samples",UPN2_068,2,25505498,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu87Arg/c.260T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),2734,49,2800,"0,0175",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,248,Tolerated,"31,66","31,04"
"low freq, many artifacts, many samples",UPN2_069,2,25505498,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu87Arg/c.260T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),4262,90,4367,"0,0206091138",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,248,Tolerated,"31,67","31,31"
many samples,UPN2_070,2,25505498,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu87Arg/c.260T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),2586,72,2666,"0,0270067517",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,248,Tolerated,"31,7","31,6"
many samples,UPN2_071,2,25505498,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu87Arg/c.260T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),3913,94,4026,"0,0233482365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,248,Tolerated,"31,79","31,69"
"low freq, many artifacts, many samples",UPN2_072,2,25505498,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu87Arg/c.260T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),5232,112,5377,"0,0208294588",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,248,Tolerated,"31,67","31,64"
"low freq, many artifacts, many samples",UPN2_073,2,25505498,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu87Arg/c.260T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),2970,44,3030,"0,0145214521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,248,Tolerated,"31,66","31,09"
"low freq, many artifacts, many samples",UPN2_075,2,25505498,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu87Arg/c.260T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),5198,70,5293,"0,0132250142",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,248,Tolerated,"31,67","31,43"
"low freq, many artifacts, many samples",UPN2_076,2,25505498,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu87Arg/c.260T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),3545,46,3606,"0,0127565169",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,248,Tolerated,"31,73","31,61"
"low freq, many artifacts, many samples",UPN2_077,2,25505498,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu87Arg/c.260T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),3282,40,3334,"0,0119976005",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,248,Tolerated,"31,74",32
"low freq, many artifacts, many samples",UPN2_078,2,25505498,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu87Arg/c.260T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),4281,57,4353,"0,0130944176",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,248,Tolerated,"31,63","31,68"
"low freq, many artifacts, many samples",UPN2_080,2,25505498,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu87Arg/c.260T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),5264,56,5342,"0,0104829652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,248,Tolerated,"31,76","31,8"
"low freq, many artifacts, many samples",UPN2_081,2,25505498,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu87Arg/c.260T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),6702,76,6808,"0,0111633373",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,248,Tolerated,"31,69","31,76"
many samples,UPN2_083,2,25505498,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu87Arg/c.260T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),4063,95,4173,"0,0227653966",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,248,Tolerated,"31,7","31,62"
"low freq, many artifacts, many samples",UPN2_084,2,25505498,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu87Arg/c.260T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),4421,53,4492,"0,0117987533",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,248,Tolerated,"31,72","31,49"
"low freq, many artifacts, many samples",UPN2_085,2,25505498,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu87Arg/c.260T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),2242,24,2274,"0,0105540897",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,248,Tolerated,"31,65","31,25"
"low freq, many artifacts, many samples",UPN2_087,2,25505498,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu87Arg/c.260T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),4052,56,4133,"0,0135494798",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,248,Tolerated,"31,7","31,16"
"low freq, many artifacts",UPN2_088,2,25505498,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu87Arg/c.260T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),2605,51,2669,"0,0191082803",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,248,Tolerated,"31,7","31,78"
"low freq, many artifacts",UPN2_041,2,25505502,C,A,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu86*/c.256G>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|A),1480,27,1507,"0,0179163902",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,85","30,22"
"low bq, low freq, many artifacts",UPN2_043,2,25505516,T,A,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp81Val/c.242A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|A),6600,68,6690,"0,0101644245",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,3,Damaging,"34,72","20,93"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,25505519,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln80Leu/c.239A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|A),10884,116,11046,"0,010501539",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,129,Tolerated,"34,13","20,52"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,25505519,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln80Leu/c.239A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|A),4396,46,4449,"0,0103394021",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,129,Tolerated,"34,09","24,65"
"low freq, many artifacts",UPN2_044,2,25505523,C,T,missense_variant(MODERATE|MISSENSE|Gcc/Acc|p.Ala79Thr/c.235G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),3905,51,3969,"0,0128495843",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-0,27",Neutral,"0,003",Damaging,"30,95","26,29"
"low freq, many artifacts, many samples",UPN2_006,2,25505529,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser77Pro/c.229T>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3681,38,3726,"0,0101986044",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,67",Neutral,345,Tolerated,"33,26","32,21"
"low freq, many artifacts",UPN2_041,2,25505530,TG,T,frameshift_variant(HIGH||cca/|p.Pro76fs/c.227delC|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),2979,38,3032,"0,0125329815",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,87",NA
"low freq, many artifacts",UPN2_048,2,25505530,TG,T,frameshift_variant(HIGH||cca/|p.Pro76fs/c.227delC|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),8203,98,8334,"0,0117590593",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,13",NA
"low freq, many artifacts",UPN2_092,2,25505536,C,G,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys74Asn/c.222G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|G),3432,62,3503,"0,017699115",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,52",Neutral,"0,004",Damaging,"33,76","32,63"
"inspected, low coverage, common artifact",UPN2_064,2,25505540,G,A,missense_variant(MODERATE|MISSENSE|tCc/tTc|p.Ser73Phe/c.218C>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|A),90,27,117,"0,2307692308",0,1,1,1,1,1,1,1,7,NA,NA,NO,NO,NO,NO,O,NO,NO,NO,NO,"-0,98",Neutral,"0,01",Damaging,"31,97","35,11"
"low freq, many artifacts",UPN2_041,2,25505549,G,A,missense_variant(MODERATE|MISSENSE|gCg/gTg|p.Ala70Val/c.209C>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|A),2970,55,3033,"0,0181338609",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,45",Neutral,"0,05",Damaging,"32,11","32,25"
"inspected, low freq, many artifacts",UPN2_041,2,25505553,G,A,missense_variant(MODERATE|MISSENSE|Cct/Tct|p.Pro69Ser/c.205C>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|A),2914,101,3034,"0,0332893869",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,22",Neutral,"0,447",Tolerated,"32,11","32,98"
"low freq, many artifacts",UPN2_044,2,25505558,T,C,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys67Arg/c.200A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),3868,73,3975,"0,0183647799",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,26",Neutral,0,Damaging,"34,15","35,48"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,25505565,T,A,missense_variant(MODERATE|MISSENSE|Acg/Tcg|p.Thr65Ser/c.193A>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|A),14089,152,14340,"0,0105997211",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,1",Neutral,201,Tolerated,"32,79","22,82"
"low freq, many artifacts, many samples",UPN2_041,2,25505574,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser62Gly/c.184A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),2975,34,3030,"0,0112211221",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,87",Neutral,"0,004",Damaging,"32,8","35,15"
"low freq, many artifacts, many samples",UPN2_048,2,25505574,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser62Gly/c.184A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),8166,96,8334,"0,0115190785",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,87",Neutral,"0,004",Damaging,"32,76","34,58"
"low freq, many artifacts, many samples",UPN2_049,2,25505574,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser62Gly/c.184A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),13980,161,14280,"0,0112745098",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,87",Neutral,"0,004",Damaging,"32,78","34,67"
"low freq, many artifacts, many samples",UPN2_039,2,25505574,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser62Gly/c.184A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),3947,42,4010,"0,0104738155",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,87",Neutral,"0,004",Damaging,"33,22","34,67"
"low freq, many artifacts, many samples",UPN2_095,2,25505574,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser62Gly/c.184A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),4582,49,4644,"0,0105512489",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,87",Neutral,"0,004",Damaging,"34,07","32,8"
"low freq, many artifacts, many samples",UPN2_104,2,25505574,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser62Gly/c.184A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|C),2361,28,2397,"0,0116812683",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,87",Neutral,"0,004",Damaging,"34,17","33,57"
"low freq, many artifacts, many samples",UPN2_006,2,25505578,C,T,splice_region_variant+synonymous_variant(LOW|SILENT|gtG/gtA|p.Val60Val/c.180G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|4|T),3678,41,3727,"0,0110008049",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,0,Neutral,1,Tolerated,"34,07","34,07"
"many samples, ins and del, homopolymer 6G, low freq, no database",UPN2_028,2,25523008,C,CG,frameshift_variant(HIGH||ccg/ccCg|p.Val60fs/c.176dupC|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|CG),1996,21,2007,"0,0104633782",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,22",NA
"many samples, ins and del, homopolymer 6G, low freq, no database",UPN2_035,2,25523008,C,CG,frameshift_variant(HIGH||ccg/ccCg|p.Val60fs/c.176dupC|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|CG),1851,23,1855,"0,0123989218",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,18",NA
"many samples, ins and del, homopolymer 6G, low freq, no database",UPN2_036,2,25523008,C,CG,frameshift_variant(HIGH||ccg/ccCg|p.Val60fs/c.176dupC|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|CG),2105,111,2112,"0,0525568182",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,28",NA
"many samples, ins and del, homopolymer 6G, low freq, no database",UPN2_039,2,25523008,C,CG,frameshift_variant(HIGH||ccg/ccCg|p.Val60fs/c.176dupC|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|CG),2465,183,2472,"0,0740291262",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,22",NA
"many samples, ins and del, homopolymer 6G, low freq, no database",UPN2_012,2,25523008,C,CG,frameshift_variant(HIGH||ccg/ccCg|p.Val60fs/c.176dupC|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|CG),2225,38,2237,"0,0169870362",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,18",NA
"many samples, ins and del, homopolymer 6G, low freq, no database",UPN2_040,2,25523008,C,CG,frameshift_variant(HIGH||ccg/ccCg|p.Val60fs/c.176dupC|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|CG),952,42,953,"0,0440713536",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"4,12E-005",NO,NO,NA,NA,NA,NA,"35,22",NA
"many samples, ins and del, homopolymer 6G, low freq, no database",UPN2_021,2,25523008,CG,C,frameshift_variant(HIGH||ccg/|p.Pro59fs/c.176delC|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|C),2644,27,2680,"0,0100746269",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,16",NA
"many samples, ins and del, homopolymer 6G, low freq, no database",UPN2_022,2,25523008,CG,C,frameshift_variant(HIGH||ccg/|p.Pro59fs/c.176delC|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|C),2655,29,2696,"0,0107566766",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,16",NA
"many samples, ins and del, homopolymer 6G, low freq, no database",UPN2_041,2,25523008,CG,C,frameshift_variant(HIGH||ccg/|p.Pro59fs/c.176delC|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|C),8230,112,8372,"0,0133779264",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,9",NA
"many samples, ins and del, homopolymer 6G, low freq, no database",UPN2_025,2,25523008,CG,C,frameshift_variant(HIGH||ccg/|p.Pro59fs/c.176delC|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|C),5667,61,5755,"0,0105994787",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,13",NA
"many samples, ins and del, homopolymer 6G, low freq, no database",UPN2_089,2,25523008,CG,C,frameshift_variant(HIGH||ccg/|p.Pro59fs/c.176delC|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|C),1712,20,1736,"0,0115207373",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,23",NA
"low freq, many artifacts, many samples",UPN2_045,2,25523008,CG,C,frameshift_variant(HIGH||ccg/|p.Pro59fs/c.176delC|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|C),4952,51,5030,"0,010139165",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,89",NA
"many samples, ins and del, homopolymer 6G, low freq, no database",UPN2_046,2,25523008,CG,C,frameshift_variant(HIGH||ccg/|p.Pro59fs/c.176delC|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|C),5199,65,5287,"0,0122943068",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,82",NA
"many samples, ins and del, homopolymer 6G, low freq, no database",UPN2_033,2,25523008,CG,C,frameshift_variant(HIGH||ccg/|p.Pro59fs/c.176delC|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|C),2195,26,2228,"0,0116696589",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,04",NA
"many samples, ins and del, homopolymer 6G, low freq, no database",UPN2_047,2,25523008,CG,C,frameshift_variant(HIGH||ccg/|p.Pro59fs/c.176delC|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|C),7224,85,7347,"0,011569348",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,93",NA
"many samples, ins and del, homopolymer 6G, low freq, no database",UPN2_048,2,25523008,CG,C,frameshift_variant(HIGH||ccg/|p.Pro59fs/c.176delC|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|C),5532,68,5614,"0,0121125757",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,77",NA
"low freq, many artifacts",UPN2_049,2,25523008,CG,C,frameshift_variant(HIGH||ccg/|p.Pro59fs/c.176delC|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|C),4413,45,4486,"0,0100312082",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,93",NA
"many samples, ins and del, homopolymer 6G, low freq, no database",UPN2_050,2,25523008,CG,C,frameshift_variant(HIGH||ccg/|p.Pro59fs/c.176delC|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|C),4560,50,4645,"0,0107642626",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,92",NA
"many samples, ins and del, homopolymer 6G, low freq, no database",UPN2_037,2,25523008,CG,C,frameshift_variant(HIGH||ccg/|p.Pro59fs/c.176delC|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|C),5612,61,5704,"0,0106942496",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,09",NA
"many samples, ins and del, homopolymer 6G, low freq, no database",UPN2_051,2,25523008,CG,C,frameshift_variant(HIGH||ccg/|p.Pro59fs/c.176delC|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|C),5627,63,5723,"0,0110082125",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,87",NA
"many samples, ins and del, homopolymer 6G, low freq, no database",UPN2_039,2,25523008,CG,C,frameshift_variant(HIGH||ccg/|p.Pro59fs/c.176delC|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|C),2426,36,2472,"0,0145631068",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,11",NA
"many samples, ins and del, homopolymer 6G, low freq, no database",UPN2_054,2,25523008,CG,C,frameshift_variant(HIGH||ccg/|p.Pro59fs/c.176delC|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|C),2644,28,2701,"0,0103665309",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,82",NA
"many samples, ins and del, homopolymer 6G, low freq, no database",UPN2_090,2,25523008,CG,C,frameshift_variant(HIGH||ccg/|p.Pro59fs/c.176delC|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|C),2167,42,2213,"0,0189787619",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,2",NA
"many samples, ins and del, homopolymer 6G, low freq, no database",UPN2_057,2,25523008,CG,C,frameshift_variant(HIGH||ccg/|p.Pro59fs/c.176delC|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|C),2754,48,2819,"0,0170273147",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,99",NA
"many samples, ins and del, homopolymer 6G, low freq, no database",UPN2_058,2,25523008,CG,C,frameshift_variant(HIGH||ccg/|p.Pro59fs/c.176delC|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|C),3249,42,3318,"0,0126582278",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,95",NA
"many samples, ins and del, homopolymer 6G, low freq, no database",UPN2_012,2,25523008,CG,C,frameshift_variant(HIGH||ccg/|p.Pro59fs/c.176delC|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|C),2199,29,2237,"0,0129637908",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,95",NA
"many samples, ins and del, homopolymer 6G, low freq, no database",UPN2_091,2,25523008,CG,C,frameshift_variant(HIGH||ccg/|p.Pro59fs/c.176delC|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|C),1846,20,1870,"0,0106951872",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,28",NA
"many samples, ins and del, homopolymer 6G, low freq, no database",UPN2_094,2,25523008,CG,C,frameshift_variant(HIGH||ccg/|p.Pro59fs/c.176delC|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|C),2734,36,2789,"0,0129078523",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,16",NA
"many samples, ins and del, homopolymer 6G, low freq, no database",UPN2_095,2,25523008,CG,C,frameshift_variant(HIGH||ccg/|p.Pro59fs/c.176delC|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|C),2436,32,2477,"0,0129188535",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,16",NA
"many samples, ins and del, homopolymer 6G, low freq, no database",UPN2_102,2,25523008,CG,C,frameshift_variant(HIGH||ccg/|p.Pro59fs/c.176delC|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|C),1473,20,1498,"0,0133511348",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,07",NA
"many samples, ins and del, homopolymer 6G, low freq, no database",UPN2_103,2,25523008,CG,C,frameshift_variant(HIGH||ccg/|p.Pro59fs/c.176delC|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|C),2492,32,2527,"0,012663237",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,16",NA
"many samples, ins and del, homopolymer 6G, low freq, no database",UPN2_104,2,25523008,CG,C,frameshift_variant(HIGH||ccg/|p.Pro59fs/c.176delC|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|C),2605,28,2640,"0,0106060606",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,16",NA
"many samples, ins and del, homopolymer 6G, low freq, no database",UPN2_108,2,25523008,CG,C,frameshift_variant(HIGH||ccg/|p.Pro59fs/c.176delC|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|C),3545,39,3593,"0,0108544392",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,13",NA
"many samples, ins and del, homopolymer 6G, low freq, no database",UPN2_110,2,25523008,CG,C,frameshift_variant(HIGH||ccg/|p.Pro59fs/c.176delC|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|C),2824,31,2871,"0,0107976315",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,25",NA
"inspected, many artifacts",UPN2_006,2,25523021,C,T,missense_variant(MODERATE|MISSENSE|cGc/cAc|p.Arg55His/c.164G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|T),1228,29,1259,"0,0230341541",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,0,Damaging,"35,34","35,1"
"low freq, many artifacts",UPN2_047,2,25523028,T,C,missense_variant(MODERATE|MISSENSE|Agg/Ggg|p.Arg53Gly/c.157A>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|C),7225,102,7342,"0,0138926723",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,93",Neutral,0,Damaging,"35,44","34,6"
"low bq, low freq, many artifacts",UPN2_081,2,25523042,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val48Gly/c.143T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|C),2385,31,2425,"0,0127835052",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,8,Damaging,"27,72","16,35"
inspected,UPN2_060,2,25523042,A,G,missense_variant(MODERATE|MISSENSE|gTg/gCg|p.Val48Ala/c.143T>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|G),589,25,623,"0,0401284109",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,029",Damaging,"28,51","34,96"
"low freq, many artifacts",UPN2_047,2,25523067,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu40Gln/c.118G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|G),7173,91,7270,"0,0125171939",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,3",Neutral,"0,007",Damaging,"34,78","35,19"
"low freq, many artifacts",UPN2_044,2,25523067,C,T,missense_variant(MODERATE|MISSENSE|Gag/Aag|p.Glu40Lys/c.118G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|T),2568,46,2617,"0,0175773787",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,41",Neutral,"0,005",Damaging,"34,77","33,52"
"low freq, many artifacts",UPN2_081,2,25523072,C,T,missense_variant(MODERATE|MISSENSE|cGc/cAc|p.Arg38His/c.113G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|T),2392,26,2423,"0,0107304994",0,0,0,0,1,0,0,1,2,0,NO,"COSM94143, COSM4641183","large_intestine, lung","2, 1",NO,rs369618387,NO,"2,47E-005",NO,NO,"-0,79",Neutral,"0,002",Damaging,"34,16","33,81"
"low freq, many artifacts",UPN2_061,2,25523090,G,A,missense_variant(MODERATE|MISSENSE|cCg/cTg|p.Pro32Leu/c.95C>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|A),2024,23,2050,"0,0112195122",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,"0,042",Damaging,"31,08","29,22"
"inspected, many artifacts",UPN2_059,2,25523094,C,T,missense_variant(MODERATE|MISSENSE|Gag/Aag|p.Glu31Lys/c.91G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|T),931,20,952,"0,0210084034",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,0,Damaging,"31,07","30,4"
"low freq, many artifacts",UPN2_061,2,25523100,G,A,stop_gained(HIGH|NONSENSE|Cag/Tag|p.Gln29*/c.85C>T|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|A),2026,24,2058,"0,0116618076",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,07","29,04"
"low freq, many artifacts",UPN2_048,2,25523100,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln29Lys/c.85C>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|T),10697,131,10857,"0,0120659482",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,23",Neutral,"0,058",Tolerated,"32,91","30,38"
"inspected, not in 2nd illumina, not in 454",UPN2_006,2,25523109,C,T,missense_variant(MODERATE|MISSENSE|Gga/Aga|p.Gly26Arg/c.76G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|T),2408,85,2496,"0,0340544872",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,"1,65E-005",NO,NO,"-0,56",Neutral,0,Damaging,"33,29","32,54"
"low freq, many artifacts",UPN2_092,2,25523110,G,C,missense_variant+splice_region_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp25Glu/c.75C>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|3|C),2599,27,2634,"0,0102505695",0,0,0,0,1,0,0,1,2,NO,NO,"COSM4583407, COSM4583406",bone,2,NO,NO,NO,NO,NO,NO,"-0,22",Neutral,1,Tolerated,"31,48","31,37"
"low freq, many artifacts",UPN2_001,2,25536798,C,T,missense_variant(MODERATE|MISSENSE|cGg/cAg|p.Arg19Gln/c.56G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),2776,29,2809,"0,0103239587",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,04",Neutral,"0,038",Damaging,"35,53","34,17"
"inspected, many artifacts",UPN2_044,2,25536821,G,T,missense_variant(MODERATE|MISSENSE|gaC/gaA|p.Asp11Glu/c.33C>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),1759,38,1806,"0,0210409745",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,11",Neutral,"0,013",Damaging,35,"35,13"
"low bq, low freq, many artifacts, many samples",UPN2_001,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),5388,88,5485,"0,0160437557",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"29,02","14,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_014,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),10606,209,10830,"0,0192982456",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,32","15,05"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_015,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),14463,266,14768,"0,0180119177",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,45","14,57"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_016,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),7445,136,7590,"0,0179183136",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,21","14,44"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_017,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),5470,110,5584,"0,0196991404",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,45","14,13"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_018,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),7820,153,7990,"0,0191489362",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,28","14,96"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_019,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),8126,137,8271,"0,016563898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,4","14,69"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_020,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),6884,134,7045,"0,019020582",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,26","14,26"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_021,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),8094,150,8258,"0,0181642044",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,29","14,24"
"low bq, bad alignment, many samples",UPN2_002,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),5937,176,6133,"0,0286972118",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,32","14,53"
"low bq, bad alignment, many samples",UPN2_003,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),1131,40,1172,"0,0341296928",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,38",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_022,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),8579,165,8770,"0,0188141391",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,27","14,7"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_023,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),9874,185,10069,"0,0183732247",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,32","14,75"
"low bq, bad alignment, many samples",UPN2_041,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),19853,718,20616,"0,0348273186",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,68","14,67"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_024,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),4929,101,5037,"0,020051618",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,31","14,33"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_025,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),13635,300,13958,"0,0214930506",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,27","14,61"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_026,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),11629,211,11863,"0,0177863947",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,49","14,64"
"low bq, bad alignment, many samples",UPN2_004,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),1321,37,1360,"0,0272058824",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,4","16,14"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_027,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),10488,173,10684,"0,0161924373",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,28","14,58"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_089,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),5903,132,6039,"0,0218579235",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,29","14,22"
"low bq, bad alignment, many samples",UPN2_042,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),25622,955,26661,"0,0358201118",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,73","14,72"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_028,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),6777,136,6922,"0,0196475007",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,44","14,57"
"low bq, bad alignment, many samples",UPN2_043,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),13699,519,14246,"0,036431279",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,66","14,47"
"low bq, bad alignment, many samples",UPN2_044,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),3361,129,3555,"0,0362869198",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,58","14,67"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_029,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),9122,182,9319,"0,0195299925",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,45","14,38"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_030,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),10605,218,10847,"0,0200977229",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,3","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_031,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),7860,80,7951,"0,0100616275",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"29,12","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_005,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),1924,25,1953,"0,0128008193",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"29,18","14,52"
"low bq, bad alignment, many samples",UPN2_045,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),21463,771,22307,"0,0345631416",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,72","14,67"
"low bq, bad alignment, many samples",UPN2_032,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),2952,70,3032,"0,0230870712",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,52","14,46"
"low bq, bad alignment, many samples",UPN2_046,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),16338,558,16963,"0,0328951247",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,75","14,59"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_033,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),7106,121,7246,"0,0166988683",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,28","15,2"
"low bq, bad alignment, many samples",UPN2_034,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),2667,61,2731,"0,0223361406",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,35","14,59"
"low bq, bad alignment, many samples",UPN2_047,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),23881,897,24866,"0,0360733532",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,77","14,49"
"low bq, bad alignment, many samples",UPN2_048,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),17153,674,17865,"0,0377273999",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,58","14,56"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_035,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),8139,160,8311,"0,0192515943",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,34","15,06"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_036,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),11031,214,11261,"0,0190036409",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,39","14,97"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_006,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),3455,69,3528,"0,0195578231",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,47","14,74"
"low bq, bad alignment, many samples",UPN2_049,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),14289,505,14856,"0,0339929995",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,59","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),17001,282,17306,"0,0162949266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"28,77","14,84"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_037,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),17304,331,17669,"0,0187333748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,33","14,76"
"low bq, bad alignment, many samples",UPN2_051,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),15368,567,15970,"0,0355040701",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,51","14,58"
"low bq, bad alignment, many samples",UPN2_052,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),13684,491,14204,"0,0345677274",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,66","14,57"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_038,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),19428,375,19838,"0,0189031152",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,38","14,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_039,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),12894,233,13145,"0,0177253709",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,5","14,79"
"low bq, bad alignment, many samples",UPN2_053,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),19715,689,20455,"0,0336836959",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,67","14,5"
"low bq, bad alignment, many samples",UPN2_054,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),9617,349,9999,"0,0349034903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,77","14,64"
"low bq, bad alignment, many samples",UPN2_007,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),14072,385,14480,"0,0265883978",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,42","14,51"
"low bq, bad alignment, many samples",UPN2_008,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),23545,661,24259,"0,0272476194",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,42","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_009,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),17630,257,17909,"0,0143503267",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"29,09","14,61"
"low bq, bad alignment, many samples",UPN2_010,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),9864,267,10138,"0,0263365555",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,51","14,52"
"low bq, bad alignment, many samples",UPN2_011,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),11111,341,11478,"0,0297090085",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,37","14,37"
"low bq, bad alignment, many samples",UPN2_055,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),20280,791,21134,"0,0374278414",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,65","14,8"
"low bq, bad alignment, many samples",UPN2_056,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),6797,253,7061,"0,0358306189",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,6","14,49"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_090,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),5291,103,5399,"0,019077607",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,35","14,35"
"low bq, bad alignment, many samples",UPN2_057,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),13079,489,13597,"0,0359638155",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,67","14,5"
"low bq, bad alignment, many samples",UPN2_058,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),12251,484,12762,"0,0379250901",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,58","14,64"
"low bq, bad alignment, many samples",UPN2_012,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),4412,142,4563,"0,0311198773",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,45","14,72"
"low bq, bad alignment, many samples",UPN2_060,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),558,34,592,"0,0574324324",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,07","14,74"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_040,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),4402,85,4493,"0,0189183174",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,41","15,01"
"low bq, bad alignment, many samples",UPN2_013,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),3572,113,3695,"0,0305818674",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,5","15,02"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_091,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),6540,133,6679,"0,0199131607",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,33","14,64"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_093,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),3553,64,3620,"0,017679558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,13","14,22"
"low bq, bad alignment, many samples",UPN2_061,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),1008,45,1053,"0,0427350427",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"25,87","14,16"
"low bq, many samples",UPN2_062,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),1461,42,1503,"0,0279441118",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"28,11",14
"low bq, bad alignment, many samples",UPN2_069,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),363,27,391,"0,0690537084",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,24",15
"low bq, bad alignment, many samples",UPN2_071,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),2059,132,2198,"0,0600545951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,05","14,43"
"low bq, bad alignment, many samples",UPN2_072,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),1432,72,1504,"0,0478723404",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,12","14,86"
"low bq, bad alignment, many samples",UPN2_075,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),1036,55,1095,"0,0502283105",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,06","14,25"
"low bq, bad alignment, many samples",UPN2_076,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),460,21,481,"0,0436590437",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,02","14,33"
"low bq, bad alignment, many samples",UPN2_077,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),447,27,478,"0,0564853556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,22","14,26"
"low bq, many samples",UPN2_080,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),637,24,661,"0,0363086233",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"28,2",14
"low bq, bad alignment, many samples",UPN2_081,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),1692,98,1797,"0,0545353367",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"25,98","14,61"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_094,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),7635,152,7791,"0,0195096907",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,47","14,93"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_095,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),6915,135,7053,"0,0191407912",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,35","14,59"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_096,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),7419,157,7588,"0,020690564",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,33","14,09"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_097,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),9357,176,9546,"0,0184370417",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,49","14,97"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_099,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),3794,76,3876,"0,0196078431",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,25","15,03"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_100,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),6480,134,6619,"0,02024475",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,34","14,27"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_101,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),5222,102,5333,"0,0191261954",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,21","14,56"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_102,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),5887,98,5999,"0,016336056",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,32","14,43"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_103,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),5771,100,5877,"0,0170154841",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,4","14,86"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_104,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),7104,131,7246,"0,0180789401",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,26","14,49"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_105,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),4889,110,5010,"0,0219560878",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,17","14,8"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_106,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),11847,230,12096,"0,0190145503",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,25","14,58"
"low bq, bad alignment, many samples",UPN2_107,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),11395,282,11692,"0,0241190558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,32","14,69"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_108,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),10055,172,10243,"0,0167919555",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,18","14,66"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_109,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),8541,164,8714,"0,0188202892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,29","14,47"
"low bq, bad alignment, low freq, many artifacts",UPN2_110,2,25536826,C,G,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly10Arg/c.28G>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),9990,165,10172,"0,0162209988",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,27","14,4"
"low bq, bad alignment, low freq, many artifacts",UPN2_044,2,25536826,C,T,missense_variant(MODERATE|MISSENSE|Ggg/Agg|p.Gly10Arg/c.28G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),3361,64,3555,"0,0180028129",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-0,2",Neutral,106,Tolerated,"26,58","25,47"
"inspected, many artifacts",UPN2_080,2,25536831,C,T,missense_variant(MODERATE|MISSENSE|gGc/gAc|p.Gly8Asp/c.23G>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),627,29,662,"0,0438066465",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,04",Neutral,"0,012",Damaging,"32,25","28,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_001,2,25536835,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser7Arg/c.19A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),5445,61,5541,"0,0110088432",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,4,Damaging,"26,8",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_005,2,25536835,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser7Arg/c.19A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),1930,27,1972,"0,0136916836",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,4,Damaging,"26,43",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_006,2,25536835,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser7Arg/c.19A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),3502,38,3550,"0,0107042254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,4,Damaging,"26,63","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_007,2,25536835,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser7Arg/c.19A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),14364,148,14566,"0,0101606481",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,4,Damaging,"27,11","14,14"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_008,2,25536835,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser7Arg/c.19A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),24026,276,24416,"0,0113040629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,4,Damaging,"26,55","14,83"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_010,2,25536835,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser7Arg/c.19A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),10044,117,10193,"0,0114784656",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,4,Damaging,"26,6","14,23"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_012,2,25536835,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser7Arg/c.19A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),4510,47,4586,"0,0102485826",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,4,Damaging,"26,92","14,28"
"low bq, low freq, many artifacts",UPN2_081,2,25536835,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser7Arg/c.19A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),1771,27,1805,"0,0149584488",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,4,Damaging,"27,49","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_021,2,25536838,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser6Thr/c.16T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),8175,89,8306,"0,0107151457",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,21",Neutral,19,Damaging,"30,06","18,38"
"low bq, low freq, many artifacts, many samples",UPN2_002,2,25536838,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser6Thr/c.16T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),6073,67,6164,"0,0108695652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,21",Neutral,19,Damaging,"28,39","16,52"
"low bq, low freq, many artifacts, many samples",UPN2_041,2,25536838,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser6Thr/c.16T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),20488,221,20834,"0,0106076606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,21",Neutral,19,Damaging,"30,3","17,46"
"low bq, low freq, many artifacts, many samples",UPN2_024,2,25536838,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser6Thr/c.16T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),4994,51,5062,"0,0100750691",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,21",Neutral,19,Damaging,"30,06","16,98"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,25536838,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser6Thr/c.16T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),26407,311,26863,"0,0115772624",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,21",Neutral,19,Damaging,"30,27","16,61"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,25536838,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser6Thr/c.16T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),22107,232,22462,"0,0103285549",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,21",Neutral,19,Damaging,"30,28","16,19"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,25536838,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser6Thr/c.16T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),16847,186,17101,"0,0108765569",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,21",Neutral,19,Damaging,"30,19","16,55"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,25536838,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser6Thr/c.16T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),24704,268,25092,"0,010680695",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,21",Neutral,19,Damaging,"30,24","16,09"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,25536838,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser6Thr/c.16T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),14044,161,14281,"0,0112737203",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,21",Neutral,19,Damaging,"30,12","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_011,2,25536838,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser6Thr/c.16T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),11336,117,11516,"0,0101597777",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,21",Neutral,19,Damaging,"28,52","15,84"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,25536838,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser6Thr/c.16T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),20922,218,21266,"0,0102511051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,21",Neutral,19,Damaging,"30,19","15,95"
"low bq, low freq, many artifacts",UPN2_012,2,25536838,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser6Thr/c.16T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),4513,51,4587,"0,011118378",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,21",Neutral,19,Damaging,"28,58","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,25536843,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met4Lys/c.11T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),26457,273,26878,"0,0101570057",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,3,Damaging,"29,52","16,75"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,25536843,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met4Lys/c.11T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),14159,151,14376,"0,0105036171",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,3,Damaging,"29,52","15,56"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,25536843,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met4Lys/c.11T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),22088,252,22472,"0,0112139551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,3,Damaging,"29,48","16,48"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,25536843,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met4Lys/c.11T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),16830,195,17115,"0,0113935145",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,3,Damaging,"29,51","17,98"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,25536843,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met4Lys/c.11T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),24732,289,25111,"0,0115089005",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,3,Damaging,"29,45","16,23"
"low bq, low freq, many artifacts, many samples",UPN2_048,2,25536843,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met4Lys/c.11T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),17680,180,17973,"0,0100150225",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,3,Damaging,"29,3","16,54"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,25536843,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met4Lys/c.11T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),14722,166,14955,"0,0110999666",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,3,Damaging,"29,5","15,54"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,25536843,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met4Lys/c.11T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),17232,190,17529,"0,0108391808",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,3,Damaging,"29,63","16,48"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,25536843,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met4Lys/c.11T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),15841,161,16082,"0,0100111926",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,3,Damaging,"29,61","17,81"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,25536843,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met4Lys/c.11T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),9918,115,10073,"0,0114166584",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,3,Damaging,"29,44","18,07"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,25536843,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met4Lys/c.11T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),20935,229,21281,"0,0107607725",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,3,Damaging,"29,39","16,36"
"low bq, low freq, many artifacts, many samples",UPN2_056,2,25536843,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met4Lys/c.11T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),6973,99,7109,"0,0139260093",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,3,Damaging,"29,19","18,52"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,25536843,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met4Lys/c.11T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),13576,143,13781,"0,0103766055",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,3,Damaging,"29,56","15,88"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,25536843,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met4Lys/c.11T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),12632,134,12831,"0,0104434573",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,3,Damaging,"29,49","16,16"
"low bq, low freq, many artifacts",UPN2_012,2,25536843,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met4Lys/c.11T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),4526,49,4589,"0,0106777076",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,3,Damaging,"28,52","19,14"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,25536844,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met4Leu/c.10A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),2186,35,2224,"0,0157374101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,14,Damaging,"28,23","16,71"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,25536844,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met4Leu/c.10A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),1770,28,1806,"0,015503876",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,14,Damaging,"28,35","14,46"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,2,25536852,A,C,start_lost(HIGH|MISSENSE|aTg/aGg|p.Met1?/c.2T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|C),1483,29,1524,"0,0190288714",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,2,Damaging,"25,79","14,48"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,2,25536852,A,C,start_lost(HIGH|MISSENSE|aTg/aGg|p.Met1?/c.2T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|C),2170,35,2227,"0,0157162101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,2,Damaging,"25,61","16,29"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,2,25536852,A,C,start_lost(HIGH|MISSENSE|aTg/aGg|p.Met1?/c.2T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|C),1478,20,1512,"0,0132275132",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,2,Damaging,"25,36","14,9"
"low bq, bad alignment, low freq, many artifacts",UPN2_081,2,25536852,A,C,start_lost(HIGH|MISSENSE|aTg/aGg|p.Met1?/c.2T>G|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|C),1772,25,1806,"0,0138427464",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,2,Damaging,"25,41","16,04"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_002,2,25536852,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),6060,72,6170,"0,0116693679",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,08",Neutral,2,Damaging,"25,67","14,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_041,2,25536852,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),20461,305,20863,"0,0146191823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,08",Neutral,2,Damaging,"26,55","16,11"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_024,2,25536852,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),4990,56,5066,"0,0110540861",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,08",Neutral,2,Damaging,"25,73","14,68"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_025,2,25536852,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),13825,154,14035,"0,0109725686",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,08",Neutral,2,Damaging,"26,21","15,98"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,2,25536852,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),26412,347,26907,"0,0128962723",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,08",Neutral,2,Damaging,"26,47","15,63"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_043,2,25536852,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),14104,200,14381,"0,0139072387",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,08",Neutral,2,Damaging,"26,57","15,8"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_044,2,25536852,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),3511,52,3573,"0,0145535964",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,08",Neutral,2,Damaging,"26,38","14,77"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_005,2,25536852,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),1944,21,1972,"0,0106490872",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,08",Neutral,2,Damaging,"25,66","16,71"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,2,25536852,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),22076,288,22486,"0,0128079694",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,08",Neutral,2,Damaging,"26,53","15,02"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,2,25536852,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),16769,270,17131,"0,0157609013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,08",Neutral,2,Damaging,"26,41","17,5"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,2,25536852,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),24642,347,25132,"0,0138070985",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,08",Neutral,2,Damaging,"26,39","17,38"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_048,2,25536852,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),17637,262,17984,"0,0145685053",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,08",Neutral,2,Damaging,"26,34","16,25"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,2,25536852,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),14681,205,14961,"0,0137022926",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,08",Neutral,2,Damaging,"26,39",16
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,2,25536852,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),17203,237,17541,"0,0135112023",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,08",Neutral,2,Damaging,"26,69","16,02"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,2,25536852,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),15814,187,16087,"0,0116242929",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,08",Neutral,2,Damaging,"26,61","15,83"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,2,25536852,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),14028,204,14305,"0,014260748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,08",Neutral,2,Damaging,"26,36","15,1"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,2,25536852,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),20271,267,20670,"0,0129172714",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,08",Neutral,2,Damaging,"26,52","16,17"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,2,25536852,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),9934,102,10081,"0,0101180438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,08",Neutral,2,Damaging,"26,48","15,55"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_007,2,25536852,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),14336,158,14578,"0,0108382494",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,08",Neutral,2,Damaging,"26,18","15,41"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_011,2,25536852,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),11357,122,11525,"0,0105856833",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,08",Neutral,2,Damaging,"25,88","16,56"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,2,25536852,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),20877,298,21290,"0,0139971818",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,08",Neutral,2,Damaging,"26,42","15,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,2,25536852,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),6972,103,7111,"0,0144846013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,08",Neutral,2,Damaging,"26,39","15,97"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,2,25536852,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),13493,177,13753,"0,0128699193",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,08",Neutral,2,Damaging,"26,48","15,85"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_058,2,25536852,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),12598,150,12837,"0,0116849731",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,08",Neutral,2,Damaging,"26,57","16,75"
"low bq, bad alignment, low freq, many artifacts",UPN2_013,2,25536852,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|T),3651,39,3705,"0,0105263158",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,08",Neutral,2,Damaging,"26,03","15,54"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,25536853,T,G,initiator_codon_variant(LOW|MISSENSE|Atg/Ctg|p.Met1?/c.1A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),22156,230,22488,"0,010227677",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,1",Neutral,1,Tolerated,"27,82","14,44"
"low bq, bad alignment, many samples",UPN2_061,2,25536853,T,G,initiator_codon_variant(LOW|MISSENSE|Atg/Ctg|p.Met1?/c.1A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),1038,29,1069,"0,0271281572",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,1",Neutral,1,Tolerated,"24,45","14,24"
"low bq, bad alignment, many samples",UPN2_062,2,25536853,T,G,initiator_codon_variant(LOW|MISSENSE|Atg/Ctg|p.Met1?/c.1A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),1480,39,1524,"0,0255905512",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,1",Neutral,1,Tolerated,"24,8",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,2,25536853,T,G,initiator_codon_variant(LOW|MISSENSE|Atg/Ctg|p.Met1?/c.1A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),2187,38,2227,"0,0170633139",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,1",Neutral,1,Tolerated,"24,57",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,2,25536853,T,G,initiator_codon_variant(LOW|MISSENSE|Atg/Ctg|p.Met1?/c.1A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),1480,30,1512,"0,0198412698",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,1",Neutral,1,Tolerated,"24,04","14,43"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_075,2,25536853,T,G,initiator_codon_variant(LOW|MISSENSE|Atg/Ctg|p.Met1?/c.1A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),1074,20,1097,"0,0182315406",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,1",Neutral,1,Tolerated,"24,88","14,65"
"low bq, bad alignment, many samples",UPN2_078,2,25536853,T,G,initiator_codon_variant(LOW|MISSENSE|Atg/Ctg|p.Met1?/c.1A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),955,26,983,"0,0264496439",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,1",Neutral,1,Tolerated,"24,44","14,5"
"low bq, bad alignment",UPN2_081,2,25536853,T,G,initiator_codon_variant(LOW|MISSENSE|Atg/Ctg|p.Met1?/c.1A>C|912|DNMT3A|protein_coding|CODING|ENST00000264709|2|G),1756,42,1806,"0,023255814",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,1",Neutral,1,Tolerated,"24,56",14
"low freq, many artifacts",UPN2_036,2,198266476,A,AT,frameshift_variant(HIGH||att/aAtt|p.Ile787fs/c.2359dupA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|AT),3997,41,4005,"0,0102372035",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,63",NA
"low freq, many artifacts, many samples",UPN2_001,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),2038,21,2071,"0,010140029",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,14",NA
"low freq, many artifacts, many samples",UPN2_014,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),3650,47,3725,"0,0126174497",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,32",NA
"low freq, many artifacts, many samples",UPN2_015,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),5593,64,5687,"0,0112537366",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,26",NA
"low freq, many artifacts, many samples",UPN2_016,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),2997,46,3063,"0,0150179563",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,36",NA
"low freq, many artifacts, many samples",UPN2_017,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),1796,24,1834,"0,0130861505",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,43",NA
"low freq, many artifacts, many samples",UPN2_018,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),2779,35,2833,"0,0123543946",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,46",NA
"low freq, many artifacts, many samples",UPN2_019,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),3206,41,3264,"0,0125612745",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,43",NA
"low freq, many artifacts, many samples",UPN2_020,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),2405,41,2463,"0,0166463662",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,42",NA
"low freq, many artifacts, many samples",UPN2_021,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),3100,42,3154,"0,0133164236",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,4",NA
"low freq, many artifacts, many samples",UPN2_002,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),2961,37,3017,"0,0122638382",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,16",NA
"low freq, many artifacts, many samples",UPN2_022,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),4000,44,4066,"0,0108214461",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,35",NA
"low freq, many artifacts, many samples",UPN2_023,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),4318,52,4413,"0,0117833673",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,39",NA
"low freq, many artifacts, many samples",UPN2_024,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),2038,26,2081,"0,0124939933",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,36",NA
"low freq, many artifacts, many samples",UPN2_025,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),4112,61,4194,"0,0145445875",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,34",NA
"low freq, many artifacts, many samples",UPN2_026,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),5283,68,5386,"0,0126253249",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,43",NA
"low freq, many artifacts, many samples",UPN2_027,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),5353,57,5423,"0,0105107874",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,39",NA
"low freq, many artifacts, many samples",UPN2_089,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),3725,52,3793,"0,0137094648",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,25",NA
"low freq, many artifacts, many samples",UPN2_028,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),4077,51,4156,"0,0122714148",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,38",NA
"low freq, many artifacts, many samples",UPN2_043,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),3403,58,3479,"0,0166714573",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,12",NA
"low freq, many artifacts, many samples",UPN2_029,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),4296,64,4407,"0,0145223508",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,34",NA
"low freq, many artifacts, many samples",UPN2_030,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),4339,71,4432,"0,0160198556",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,35",NA
"low freq, many artifacts, many samples",UPN2_031,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),2289,30,2336,"0,0128424658",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,43",NA
"low freq, many artifacts, many samples",UPN2_045,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),2906,36,2966,"0,012137559",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,3",NA
"low freq, many artifacts, many samples",UPN2_046,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),4980,54,5069,"0,0106529888",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,1",NA
"low freq, many artifacts, many samples",UPN2_033,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),3521,49,3588,"0,0136566332",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,5",NA
"low freq, many artifacts, many samples",UPN2_034,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),1547,29,1586,"0,0182849937",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,35",NA
"low freq, many artifacts, many samples",UPN2_035,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),3811,51,3874,"0,0131646877",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,3",NA
"low freq, many artifacts, many samples",UPN2_036,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),3928,51,4005,"0,0127340824",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,35",NA
many samples,UPN2_006,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),1376,33,1415,"0,0233215548",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,08",NA
"low freq, many artifacts, many samples",UPN2_050,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),3453,57,3532,"0,0161381653",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,25",NA
"low freq, many artifacts, many samples",UPN2_037,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),6073,88,6192,"0,0142118863",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,25",NA
"low freq, many artifacts, many samples",UPN2_051,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),4251,58,4341,"0,0133609767",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,29",NA
"low freq, many artifacts, many samples",UPN2_052,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),3696,40,3762,"0,0106326422",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,13",NA
"low freq, many artifacts, many samples",UPN2_038,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),7356,102,7509,"0,0135836996",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,39",NA
"low freq, many artifacts, many samples",UPN2_039,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),3277,56,3353,"0,0167014614",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,29",NA
"low freq, many artifacts, many samples",UPN2_053,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),5747,74,5872,"0,0126021798",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,12",NA
"low freq, many artifacts, many samples",UPN2_054,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),4071,60,4160,"0,0144230769",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,23",NA
"low freq, many artifacts, many samples",UPN2_007,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),5710,94,5843,"0,0160876262",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,1",NA
"low freq, many artifacts, many samples",UPN2_008,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),6887,79,7011,"0,0112680074",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,05",NA
"low freq, many artifacts, many samples",UPN2_009,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),5127,69,5239,"0,0131704524",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,04",NA
"low freq, many artifacts, many samples",UPN2_010,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),4594,53,4674,"0,0113393239",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,06",NA
"low freq, many artifacts, many samples",UPN2_011,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),6349,95,6493,"0,0146311412",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,94",NA
"low freq, many artifacts, many samples",UPN2_055,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),4328,59,4416,"0,0133605072",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,13",NA
"low freq, many artifacts, many samples",UPN2_090,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),2757,34,2815,"0,0120781528",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,47",NA
"low freq, many artifacts, many samples",UPN2_057,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),5600,92,5721,"0,0160811047",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,18",NA
"low freq, many artifacts, many samples",UPN2_058,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),6726,85,6868,"0,0123762376",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,11",NA
"low freq, many artifacts, many samples",UPN2_060,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),4516,58,4607,"0,0125895377",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,17",NA
"low freq, many artifacts, many samples",UPN2_040,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),2544,40,2599,"0,0153905348",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,4",NA
"low freq, many artifacts, many samples",UPN2_013,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),1512,22,1546,"0,0142302717",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,28",NA
"low freq, many artifacts, many samples",UPN2_092,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),2212,41,2255,"0,0181818182",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,44",NA
"low freq, many artifacts, many samples",UPN2_093,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),2916,60,2990,"0,0200668896",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,53",NA
"low freq, many artifacts, many samples",UPN2_062,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),3393,48,3460,"0,0138728324",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,9",NA
"low freq, many artifacts, many samples",UPN2_063,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),4767,52,4853,"0,0107150216",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,98",NA
"low freq, many artifacts, many samples",UPN2_065,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),3010,31,3056,"0,0101439791",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,03",NA
"low freq, many artifacts, many samples",UPN2_066,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),15066,211,15379,"0,0137200078",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,07",NA
"low freq, many artifacts, many samples",UPN2_067,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),17876,207,18168,"0,0113936592",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,04",NA
"low freq, many artifacts, many samples",UPN2_068,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),9525,124,9708,"0,0127729707",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,35,NA
"low freq, many artifacts, many samples",UPN2_070,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),4795,61,4884,"0,0124897625",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,98",NA
"low freq, many artifacts, many samples",UPN2_071,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),2264,28,2310,"0,0121212121",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,96",NA
"low freq, many artifacts, many samples",UPN2_072,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),2135,36,2180,"0,0165137615",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,02",NA
"low freq, many artifacts, many samples",UPN2_073,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),1751,24,1782,"0,0134680135",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,9",NA
"low freq, many artifacts, many samples",UPN2_074,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),5659,76,5769,"0,0131738603",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,01",NA
"low freq, many artifacts, many samples",UPN2_075,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),5935,94,6073,"0,0154783468",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,07",NA
"low freq, many artifacts, many samples",UPN2_077,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),8367,106,8530,"0,0124267292",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,97",NA
"low freq, many artifacts, many samples",UPN2_078,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),4681,65,4777,"0,0136068662",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,95",NA
"low freq, many artifacts, many samples",UPN2_079,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),3461,46,3526,"0,0130459444",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,04",NA
"low freq, many artifacts, many samples",UPN2_080,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),3022,45,3079,"0,0146151348",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,16",NA
"low freq, many artifacts, many samples",UPN2_082,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),10153,148,10364,"0,0142802007",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,06",NA
"low freq, many artifacts, many samples",UPN2_083,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),7963,94,8106,"0,0115963484",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,06",NA
"low freq, many artifacts, many samples",UPN2_084,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),9740,140,9947,"0,0140745954",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,89",NA
"low freq, many artifacts, many samples",UPN2_085,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),14617,215,14935,"0,0143957148",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,9",NA
"low freq, many artifacts, many samples",UPN2_086,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),14376,164,14603,"0,0112305691",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,9",NA
"low freq, many artifacts, many samples",UPN2_087,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),11022,154,11250,"0,0136888889",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,98",NA
"low freq, many artifacts, many samples",UPN2_088,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),7654,111,7801,"0,014228945",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,09",NA
"low freq, many artifacts, many samples",UPN2_095,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),3728,49,3796,"0,0129083246",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,38",NA
"low freq, many artifacts, many samples",UPN2_096,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),3013,36,3061,"0,0117608625",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,47",NA
"low freq, many artifacts, many samples",UPN2_097,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),2813,31,2852,"0,0108695652",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,4",NA
"low freq, many artifacts, many samples",UPN2_098,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),2683,44,2735,"0,0160877514",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,29",NA
"low freq, many artifacts, many samples",UPN2_099,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),1967,35,2010,"0,0174129353",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,47",NA
"low freq, many artifacts, many samples",UPN2_100,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),1606,22,1635,"0,0134556575",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,53",NA
"low freq, many artifacts, many samples",UPN2_101,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),3086,43,3143,"0,0136811963",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,37",NA
"low freq, many artifacts, many samples",UPN2_102,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),3859,49,3923,"0,012490441",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,47",NA
"low freq, many artifacts, many samples",UPN2_103,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),2485,30,2526,"0,0118764846",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,42",NA
"low freq, many artifacts, many samples",UPN2_104,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),2881,32,2924,"0,0109439124",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,42",NA
"low freq, many artifacts, many samples",UPN2_107,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),4712,61,4793,"0,0127268934",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,38",NA
"low freq, many artifacts, many samples",UPN2_109,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),2889,37,2937,"0,012597889",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,44",NA
"low freq, many artifacts",UPN2_111,2,198266476,AT,A,frameshift_variant(HIGH||att/|p.Ile787fs/c.2359delA|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),3793,52,3861,"0,0134680135",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,4",NA
"low freq, many artifacts",UPN2_044,2,198266507,A,T,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe777Ile/c.2329T>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),1224,29,1261,"0,0229976209",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,76",Deleterious,0,Damaging,"34,2","33,9"
"low bq, low freq, many artifacts, many samples",UPN2_001,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),3993,62,4075,"0,0152147239",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"31,13","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_017,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),3552,43,3612,"0,0119047619",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"29,3","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_002,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),5892,66,5976,"0,0110441767",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"31,12","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),2515,41,2579,"0,0158976347",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"28,93","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),6595,144,6813,"0,0211360634",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"28,87","14,47"
"low bq, many samples",UPN2_044,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),2406,55,2482,"0,0221595488",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"29,04",14
"low bq, low freq, many artifacts, many samples",UPN2_031,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),4522,48,4601,"0,0104325147",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"29,13","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),5661,92,5830,"0,015780446",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"28,61","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),9675,168,9926,"0,0169252468",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"28,85","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),2316,32,2360,"0,013559322",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"28,94","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_006,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),2753,32,2791,"0,0114654246",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"30,99","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),2152,46,2216,"0,0207581227",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"29,2","15,57"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),6765,123,6950,"0,0176978417",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"28,85","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),8294,129,8517,"0,0151461782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"28,97","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),7209,128,7401,"0,0172949601",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"29,11","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),11219,181,11484,"0,0157610589",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"28,94","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),7952,121,8168,"0,0148139079",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"29,02","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_007,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),11306,164,11510,"0,0142484796",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"30,87","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_008,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),13576,174,13809,"0,0126004779",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"31,2","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_009,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),10150,143,10331,"0,0138418353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"30,91","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_010,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),9063,131,9212,"0,0142205818",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,31,"15,03"
"low bq, low freq, many artifacts, many samples",UPN2_011,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),12542,193,12776,"0,0151064496",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"30,83","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),8400,150,8646,"0,0173490632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,29,"14,77"
"low bq, low freq, many artifacts, many samples",UPN2_090,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),5492,63,5583,"0,0112842558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"30,07","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),10913,194,11221,"0,0172890117",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"28,89","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),13074,247,13416,"0,0184108527",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"28,81","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_012,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),5062,83,5177,"0,0160324512",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"31,04","15,37"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),8858,110,9048,"0,0121573828",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"29,72","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_040,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),5048,53,5135,"0,0103213242",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"29,26","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_013,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),2988,45,3046,"0,0147734734",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"31,02","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_091,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),5071,53,5150,"0,0102912621",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"29,93","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_093,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),5843,60,5933,"0,0101129277",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"30,13","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),9254,124,9451,"0,0131203047",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"29,59","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),9351,124,9560,"0,0129707113",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"29,64","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),1120,20,1148,"0,0174216028",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"29,59","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),5855,85,5992,"0,0141855808",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"29,39","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_066,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),29517,426,30212,"0,0141003575",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"29,4","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_067,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),35050,399,35716,"0,0111714638",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"29,41","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),18695,241,19089,"0,012625072",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"29,74","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),16259,216,16594,"0,013016753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"29,56","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),9382,128,9579,"0,0133625639",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"29,61","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),4440,56,4525,"0,0123756906",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"29,34","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),3438,48,3512,"0,013667426",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"29,2","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),11125,128,11356,"0,0112715745",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"29,47","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),11671,163,11938,"0,0136538784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"29,33","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),13572,154,13859,"0,0111119128",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"29,74","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),16425,223,16769,"0,0132983481",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"29,55","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),9183,108,9398,"0,0114918068",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"29,68","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),6773,86,6940,"0,0123919308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"29,56","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),5962,79,6083,"0,012987013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"29,49","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),1681,21,1718,"0,0122235157",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"29,47","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),19859,268,20311,"0,0131948205",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"29,44","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),15649,163,15952,"0,0102181545",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"29,77","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),19116,245,19525,"0,0125480154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"29,59","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),28742,362,29344,"0,0123364231",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"29,4","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_086,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),28150,327,28718,"0,0113865868",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"29,61","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_087,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),21634,258,22075,"0,0116874292",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"29,42","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_088,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),15017,175,15330,"0,0114155251",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"29,46","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_094,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),4172,44,4238,"0,0103822558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"30,03","15,98"
"low bq, low freq, many artifacts, many samples",UPN2_095,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),7428,76,7534,"0,0100876029",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"30,07","14,18"
"low bq, low freq, many artifacts, many samples",UPN2_097,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),5573,66,5660,"0,0116607774",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"29,93","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_098,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),5325,57,5411,"0,0105340972",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"30,2",14
"low bq, low freq, many artifacts, many samples",UPN2_104,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),5708,59,5793,"0,0101847057",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"30,15","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_105,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),3511,38,3562,"0,010668164",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"30,05","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_106,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),2345,34,2382,"0,0142737196",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"30,1","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_109,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),5735,59,5828,"0,0101235415",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"30,32","14,95"
"low bq, low freq, many artifacts",UPN2_111,2,198266552,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala762Ser/c.2284G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),7534,85,7643,"0,0111212875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,68,Tolerated,"30,19","14,81"
"low bq, low freq, many artifacts",UPN2_045,2,198266552,C,T,missense_variant(MODERATE|MISSENSE|Gcc/Acc|p.Ala762Thr/c.2284G>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),5661,73,5830,"0,0125214408",0,0,0,0,0,0,0,1,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,85",Deleterious,"0,08",Tolerated,"28,61","26,58"
"low bq, low freq, many artifacts, many samples",UPN2_089,2,198266560,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala759Glu/c.2276C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),7443,79,7532,"0,010488582",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,623,Tolerated,"28,18","17,39"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,198266560,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala759Glu/c.2276C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),2552,26,2591,"0,0100347356",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,623,Tolerated,"29,68","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,198266560,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala759Glu/c.2276C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),6757,69,6846,"0,0100788782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,623,Tolerated,"29,62",14
"low bq, low freq, many artifacts, many samples",UPN2_046,2,198266560,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala759Glu/c.2276C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),9855,106,9989,"0,0106116728",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,623,Tolerated,"29,6","17,91"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,198266560,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala759Glu/c.2276C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),2199,24,2227,"0,0107768298",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,623,Tolerated,"29,76",14
"low bq, low freq, many artifacts, many samples",UPN2_050,2,198266560,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala759Glu/c.2276C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),6870,93,6987,"0,0133104337",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,623,Tolerated,"29,37","16,38"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,198266560,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala759Glu/c.2276C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),8449,87,8558,"0,0101659266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,623,Tolerated,"29,58","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,198266560,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala759Glu/c.2276C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),11132,115,11276,"0,010198652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,623,Tolerated,"29,55","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,198266560,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala759Glu/c.2276C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),6762,70,6845,"0,0102264427",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,623,Tolerated,"28,82","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,198266560,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala759Glu/c.2276C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),5955,63,6030,"0,0104477612",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,623,Tolerated,"28,71","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_066,2,198266560,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala759Glu/c.2276C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),29931,316,30343,"0,0104142636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,623,Tolerated,"28,79","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,198266560,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala759Glu/c.2276C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),4251,45,4303,"0,0104578201",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,623,Tolerated,"28,93",14
"low bq, low freq, many artifacts, many samples",UPN2_073,2,198266560,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala759Glu/c.2276C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),3483,42,3530,"0,011898017",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,623,Tolerated,"28,89","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,198266560,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala759Glu/c.2276C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),11850,126,12002,"0,0104982503",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,623,Tolerated,"28,83","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,198266560,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala759Glu/c.2276C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),6886,79,6975,"0,0113261649",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,623,Tolerated,"28,84","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,198266560,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala759Glu/c.2276C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),6028,62,6105,"0,0101556102",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,623,Tolerated,"28,95",15
"low bq, low freq, many artifacts",UPN2_087,2,198266560,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala759Glu/c.2276C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),21899,241,22189,"0,0108612376",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,623,Tolerated,"28,78","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,198266564,C,A,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp758Tyr/c.2272G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),2445,35,2498,"0,014011209",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,57",Deleterious,9,Damaging,"30,08","15,83"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,198266564,C,A,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp758Tyr/c.2272G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),8106,93,8221,"0,0113124924",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,57",Deleterious,9,Damaging,"30,29","17,51"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,198266564,C,A,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp758Tyr/c.2272G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),8593,93,8711,"0,0106761566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,57",Deleterious,9,Damaging,30,"16,16"
"low bq, low freq, many artifacts",UPN2_078,2,198266564,C,A,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp758Tyr/c.2272G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),9284,97,9450,"0,0102645503",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,57",Deleterious,9,Damaging,"29,78","15,48"
"low bq, low freq, many artifacts",UPN2_047,2,198266565,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met757Ile/c.2271G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),2323,37,2367,"0,0156316012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,2,Damaging,"29,61","24,46"
"low bq, low freq, many artifacts, many samples",UPN2_001,2,198266572,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro755His/c.2264C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),4049,45,4100,"0,0109756098",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,64",Deleterious,0,Damaging,"31,03","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,198266572,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro755His/c.2264C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),2555,29,2591,"0,0111925897",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,64",Deleterious,0,Damaging,"27,87",14
"low bq, low freq, many artifacts, many samples",UPN2_043,2,198266572,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro755His/c.2264C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),6747,92,6861,"0,013409124",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,64",Deleterious,0,Damaging,"27,92","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,198266572,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro755His/c.2264C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),2463,32,2498,"0,0128102482",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,64",Deleterious,0,Damaging,"27,86","16,19"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,198266572,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro755His/c.2264C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),5778,81,5872,"0,0137942779",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,64",Deleterious,0,Damaging,"27,81",14
"low bq, low freq, many artifacts, many samples",UPN2_046,2,198266572,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro755His/c.2264C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),9825,124,9998,"0,0124024805",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,64",Deleterious,0,Damaging,"27,83","14,06"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,198266572,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro755His/c.2264C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),2196,30,2229,"0,0134589502",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,64",Deleterious,0,Damaging,"27,8",14
"low bq, low freq, many artifacts, many samples",UPN2_050,2,198266572,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro755His/c.2264C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),6897,82,7002,"0,0117109397",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,64",Deleterious,0,Damaging,"27,87","15,55"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,198266572,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro755His/c.2264C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),8442,102,8572,"0,0118992067",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,64",Deleterious,0,Damaging,"28,12","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,198266572,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro755His/c.2264C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),7328,96,7446,"0,0128928284",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,64",Deleterious,0,Damaging,"28,04","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,198266572,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro755His/c.2264C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),8077,112,8229,"0,0136104022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,64",Deleterious,0,Damaging,"27,96","14,18"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,198266572,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro755His/c.2264C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),11127,126,11292,"0,0111583422",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,64",Deleterious,0,Damaging,"27,9","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,198266572,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro755His/c.2264C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),13340,179,13551,"0,0132093572",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,64",Deleterious,0,Damaging,"27,98","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,198266572,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro755His/c.2264C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),8967,106,9106,"0,0116406765",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,64",Deleterious,0,Damaging,"27,73","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,198266572,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro755His/c.2264C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),9364,115,9510,"0,0120925342",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,64",Deleterious,0,Damaging,"27,68","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,198266572,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro755His/c.2264C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),6740,85,6854,"0,0124015174",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,64",Deleterious,0,Damaging,"27,76","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,198266572,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro755His/c.2264C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),9438,132,9613,"0,0137314054",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,64",Deleterious,0,Damaging,"27,72","14,2"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,198266572,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro755His/c.2264C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),5932,83,6043,"0,0137348999",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,64",Deleterious,0,Damaging,"27,66","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_066,2,198266572,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro755His/c.2264C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),29888,391,30379,"0,0128707331",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,64",Deleterious,0,Damaging,"27,64","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_067,2,198266572,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro755His/c.2264C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),35394,447,35969,"0,012427368",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,64",Deleterious,0,Damaging,"27,58","14,2"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,198266572,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro755His/c.2264C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),18879,255,19211,"0,0132736453",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,64",Deleterious,0,Damaging,"27,74","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,198266572,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro755His/c.2264C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),16446,196,16714,"0,0117266962",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,64",Deleterious,0,Damaging,"27,63","14,18"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,198266572,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro755His/c.2264C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),9494,119,9654,"0,0123264968",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,64",Deleterious,0,Damaging,"27,58","14,11"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,198266572,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro755His/c.2264C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),4490,51,4561,"0,0111817584",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,64",Deleterious,0,Damaging,"27,7",14
"low bq, low freq, many artifacts, many samples",UPN2_072,2,198266572,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro755His/c.2264C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),4217,71,4308,"0,0164809656",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,64",Deleterious,0,Damaging,"27,46","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,198266572,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro755His/c.2264C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),3482,42,3538,"0,0118711136",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,64",Deleterious,0,Damaging,"27,66","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,198266572,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro755His/c.2264C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),11217,136,11408,"0,0119214586",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,64",Deleterious,0,Damaging,"27,5","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,198266572,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro755His/c.2264C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),11822,147,12021,"0,0122286",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,64",Deleterious,0,Damaging,"27,69","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,198266572,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro755His/c.2264C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),13701,158,13920,"0,0113505747",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,64",Deleterious,0,Damaging,"27,72","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,198266572,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro755His/c.2264C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),16614,220,16886,"0,0130285444",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,64",Deleterious,0,Damaging,"27,63","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,198266572,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro755His/c.2264C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),9269,166,9455,"0,0175568482",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,64",Deleterious,0,Damaging,"27,65","18,99"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,198266572,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro755His/c.2264C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),6871,85,6983,"0,0121724187",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,64",Deleterious,0,Damaging,"27,53","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,198266572,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro755His/c.2264C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),6006,74,6109,"0,0121132755",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,64",Deleterious,0,Damaging,"27,84","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,198266572,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro755His/c.2264C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),20098,260,20456,"0,0127102073",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,64",Deleterious,0,Damaging,"27,6","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,198266572,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro755His/c.2264C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),15845,174,16067,"0,0108296508",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,64",Deleterious,0,Damaging,"27,62","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,198266572,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro755His/c.2264C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),19326,280,19674,"0,0142319813",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,64",Deleterious,0,Damaging,"27,72","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,198266572,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro755His/c.2264C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),28985,430,29537,"0,014558012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,64",Deleterious,0,Damaging,"27,7","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_086,2,198266572,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro755His/c.2264C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),28399,397,28908,"0,0137332226",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,64",Deleterious,0,Damaging,"27,67","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_087,2,198266572,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro755His/c.2264C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),21874,283,22225,"0,0127334083",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,64",Deleterious,0,Damaging,"27,66","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_088,2,198266572,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro755His/c.2264C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),15159,217,15423,"0,0140698956",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,64",Deleterious,0,Damaging,"27,59","14,99"
"low bq, low freq, many artifacts",UPN2_111,2,198266572,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro755His/c.2264C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),7592,80,7682,"0,0104139547",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,64",Deleterious,0,Damaging,"27,25",14
"low bq, low freq, many artifacts, many samples",UPN2_047,2,198266573,G,T,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro755Thr/c.2263C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),2323,35,2369,"0,0147741663",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,1,Damaging,"29,11","24,71"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,198266573,G,T,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro755Thr/c.2263C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),2202,24,2230,"0,0107623318",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,1,Damaging,"28,98","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,198266573,G,T,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro755Thr/c.2263C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),6906,72,7005,"0,0102783726",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,1,Damaging,"28,77",14
"low bq, low freq, many artifacts, many samples",UPN2_060,2,198266573,G,T,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro755Thr/c.2263C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),8996,92,9107,"0,0101021192",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,1,Damaging,"29,14","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,198266573,G,T,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro755Thr/c.2263C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),9478,111,9613,"0,0115468636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,1,Damaging,"29,22","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_066,2,198266573,G,T,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro755Thr/c.2263C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),29975,306,30381,"0,0100720845",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,1,Damaging,"29,08","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,198266573,G,T,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro755Thr/c.2263C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),18950,196,19214,"0,0102008952",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,1,Damaging,"29,28","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,198266573,G,T,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro755Thr/c.2263C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),16492,179,16715,"0,0107089441",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,1,Damaging,"29,16","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,198266573,G,T,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro755Thr/c.2263C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),3482,37,3538,"0,0104578858",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,1,Damaging,"29,24","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,198266573,G,T,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro755Thr/c.2263C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),6873,72,6984,"0,0103092784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,1,Damaging,"29,18","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,198266573,G,T,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro755Thr/c.2263C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),6030,64,6110,"0,0104746318",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,1,Damaging,"29,17","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,198266573,G,T,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro755Thr/c.2263C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),20162,218,20457,"0,010656499",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,1,Damaging,"29,11","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,198266573,G,T,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro755Thr/c.2263C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),29156,300,29538,"0,0101564087",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,1,Damaging,"29,12","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_086,2,198266573,G,T,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro755Thr/c.2263C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),28532,290,28911,"0,0100307841",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,1,Damaging,"29,16","14,27"
"low bq, low freq, many artifacts",UPN2_087,2,198266573,G,T,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro755Thr/c.2263C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),21938,226,22228,"0,0101673565",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,1,Damaging,"29,15","14,25"
"low freq, many artifacts",UPN2_044,2,198266576,T,C,missense_variant(MODERATE|MISSENSE|Att/Gtt|p.Ile754Val/c.2260A>G|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|C),2447,47,2499,"0,018807523",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,96",Neutral,"0,023",Damaging,"32,32","31,74"
"low freq, many artifacts",UPN2_006,2,198266578,A,T,missense_variant(MODERATE|MISSENSE|cTt/cAt|p.Leu753His/c.2258T>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),2756,48,2808,"0,0170940171",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"34,78","32,79"
"low freq, many artifacts",UPN2_006,2,198266582,A,G,missense_variant(MODERATE|MISSENSE|Tat/Cat|p.Tyr752His/c.2254T>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|G),2747,41,2797,"0,0146585627",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,"0,07",Tolerated,"33,63","34,27"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,198266590,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala749Asp/c.2246C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),3433,38,3484,"0,0109070034",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,0,Damaging,"30,68","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,198266590,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala749Asp/c.2246C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),5687,62,5761,"0,0107620205",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,0,Damaging,"31,04","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,198266590,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala749Asp/c.2246C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),4029,49,4092,"0,0119745846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,0,Damaging,"30,8","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,198266590,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala749Asp/c.2246C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),4266,50,4334,"0,0115366867",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,0,Damaging,"30,91","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,198266590,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala749Asp/c.2246C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),6619,77,6718,"0,0114617446",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,0,Damaging,"31,35","15,31"
"low bq, low freq, many artifacts, many samples",UPN2_012,2,198266590,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala749Asp/c.2246C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),2557,26,2588,"0,0100463679",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,0,Damaging,"33,2","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,198266590,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala749Asp/c.2246C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),4710,48,4782,"0,0100376412",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,0,Damaging,"31,56","15,46"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,198266590,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala749Asp/c.2246C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),2226,29,2264,"0,0128091873",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,0,Damaging,"31,47",14
"low bq, low freq, many artifacts, many samples",UPN2_074,2,198266590,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala749Asp/c.2246C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),5594,61,5674,"0,0107507931",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,0,Damaging,"31,67",14
"low bq, low freq, many artifacts, many samples",UPN2_077,2,198266590,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala749Asp/c.2246C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),8277,87,8399,"0,010358376",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,0,Damaging,"31,55","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,198266590,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala749Asp/c.2246C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),4640,53,4706,"0,0112622184",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,0,Damaging,"31,36","14,75"
"low bq, low freq, many artifacts",UPN2_082,2,198266590,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala749Asp/c.2246C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),9997,120,10152,"0,011820331",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,0,Damaging,"31,44",15
"low bq, low freq, many artifacts",UPN2_073,2,198266591,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala749Ser/c.2245G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|A),1734,20,1760,"0,0113636364",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,48",Neutral,14,Damaging,"32,31","15,3"
"low bq, low freq, many artifacts",UPN2_052,2,198266599,A,T,missense_variant(MODERATE|MISSENSE|tTc/tAc|p.Phe746Tyr/c.2237T>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),3654,39,3709,"0,0105149636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,"0,1",Tolerated,"33,9","17,62"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,198266602,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala745Asp/c.2234C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),2878,31,2916,"0,0106310014",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,1,Damaging,"31,62",14
"low bq, low freq, many artifacts, many samples",UPN2_050,2,198266602,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala745Asp/c.2234C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),3433,35,3488,"0,0100344037",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,1,Damaging,"31,39",14
"low bq, low freq, many artifacts, many samples",UPN2_054,2,198266602,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala745Asp/c.2234C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),4036,42,4094,"0,0102589155",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,1,Damaging,"31,43","16,74"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,198266602,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala745Asp/c.2234C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),4261,57,4336,"0,0131457565",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,1,Damaging,"31,44",17
"low bq, low freq, many artifacts, many samples",UPN2_066,2,198266602,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala745Asp/c.2234C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),14891,169,15109,"0,0111853862",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,1,Damaging,"32,16","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_067,2,198266602,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala745Asp/c.2234C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),17656,201,17903,"0,0112271686",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,1,Damaging,"32,27","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,198266602,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala745Asp/c.2234C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),2230,28,2269,"0,012340238",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,1,Damaging,"32,16",14
"low bq, low freq, many artifacts, many samples",UPN2_082,2,198266602,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala745Asp/c.2234C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),10010,128,10171,"0,0125847999",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,1,Damaging,"32,04","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,198266602,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala745Asp/c.2234C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),7876,94,7998,"0,0117529382",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,1,Damaging,"32,05",14
"low bq, low freq, many artifacts",UPN2_085,2,198266602,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala745Asp/c.2234C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),14506,150,14701,"0,0102033875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,1,Damaging,"32,15","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,198266605,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala744Asp/c.2231C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),3425,43,3488,"0,0123279817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-5,56",Deleterious,0,Damaging,"31,47","16,26"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,198266605,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala744Asp/c.2231C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),4186,45,4255,"0,0105757932",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-5,56",Deleterious,0,Damaging,"31,82","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,198266605,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala744Asp/c.2231C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),5686,60,5773,"0,0103932098",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-5,56",Deleterious,0,Damaging,"31,53",14
"low bq, low freq, many artifacts, many samples",UPN2_054,2,198266605,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala744Asp/c.2231C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),4027,47,4097,"0,0114718086",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-5,56",Deleterious,0,Damaging,"31,73","15,4"
"low bq, low freq, many artifacts, many samples",UPN2_011,2,198266605,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala744Asp/c.2231C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),6326,71,6406,"0,0110833594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-5,56",Deleterious,0,Damaging,"33,28","16,24"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,198266605,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala744Asp/c.2231C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),6621,77,6729,"0,0114430079",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-5,56",Deleterious,0,Damaging,"31,66","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,198266605,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala744Asp/c.2231C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),4440,49,4526,"0,0108263367",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-5,56",Deleterious,0,Damaging,"32,11","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,198266605,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala744Asp/c.2231C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),4650,51,4718,"0,0108096651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-5,56",Deleterious,0,Damaging,"31,87","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,198266605,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala744Asp/c.2231C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),3360,37,3415,"0,0108345534",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-5,56",Deleterious,0,Damaging,"31,97","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,198266605,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala744Asp/c.2231C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),4722,49,4789,"0,0102317812",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-5,56",Deleterious,0,Damaging,"31,85","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,198266605,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala744Asp/c.2231C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),2953,34,3001,"0,0113295568",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-5,56",Deleterious,0,Damaging,"32,09",14
"low bq, low freq, many artifacts, many samples",UPN2_066,2,198266605,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala744Asp/c.2231C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),14888,176,15118,"0,0116417516",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-5,56",Deleterious,0,Damaging,"31,78","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_067,2,198266605,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala744Asp/c.2231C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),17654,208,17912,"0,0116123269",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-5,56",Deleterious,0,Damaging,"31,97","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,198266605,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala744Asp/c.2231C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),9442,98,9568,"0,0102424749",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-5,56",Deleterious,0,Damaging,"31,88","14,13"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,198266605,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala744Asp/c.2231C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),8182,89,8303,"0,0107190172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-5,56",Deleterious,0,Damaging,"31,86","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,198266605,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala744Asp/c.2231C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),4726,62,4806,"0,012900541",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-5,56",Deleterious,0,Damaging,"31,79","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,198266605,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala744Asp/c.2231C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),2230,27,2269,"0,0118995152",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-5,56",Deleterious,0,Damaging,"31,73","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,198266605,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala744Asp/c.2231C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),2122,22,2152,"0,0102230483",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-5,56",Deleterious,0,Damaging,"31,84",15
"low bq, low freq, many artifacts, many samples",UPN2_073,2,198266605,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala744Asp/c.2231C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),1731,27,1761,"0,0153321976",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-5,56",Deleterious,0,Damaging,"32,06","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,198266605,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala744Asp/c.2231C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),6835,77,6936,"0,0111014994",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-5,56",Deleterious,0,Damaging,"31,86",14
"low bq, low freq, many artifacts, many samples",UPN2_077,2,198266605,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala744Asp/c.2231C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),8278,93,8403,"0,0110674759",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-5,56",Deleterious,0,Damaging,"31,93","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,198266605,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala744Asp/c.2231C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),4631,66,4712,"0,0140067912",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-5,56",Deleterious,0,Damaging,"31,83","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,198266605,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala744Asp/c.2231C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),3432,36,3476,"0,0103567319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-5,56",Deleterious,0,Damaging,"31,98","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,198266605,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala744Asp/c.2231C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),10018,115,10173,"0,0113044333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-5,56",Deleterious,0,Damaging,"31,84","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,198266605,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala744Asp/c.2231C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),9652,101,9781,"0,0103261425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-5,56",Deleterious,0,Damaging,"31,85","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,198266605,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala744Asp/c.2231C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),14466,164,14702,"0,0111549449",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-5,56",Deleterious,0,Damaging,"32,01","15,42"
"low bq, low freq, many artifacts, many samples",UPN2_086,2,198266605,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala744Asp/c.2231C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),14181,151,14384,"0,0104977753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-5,56",Deleterious,0,Damaging,"31,82","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_087,2,198266605,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala744Asp/c.2231C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),10898,113,11049,"0,0102271699",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-5,56",Deleterious,0,Damaging,"31,95","14,27"
"low bq, low freq, many artifacts",UPN2_088,2,198266605,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala744Asp/c.2231C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),7550,85,7666,"0,0110879207",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-5,56",Deleterious,0,Damaging,"32,04","14,96"
"low freq, many artifacts",UPN2_006,2,198266608,A,G,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu743Ser/c.2228T>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|G),1372,23,1401,"0,0164168451",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,1",Deleterious,0,Damaging,"34,6","35,83"
"low bq, low freq, many artifacts",UPN2_044,2,198266608,A,T,stop_gained(HIGH|NONSENSE|tTg/tAg|p.Leu743*/c.2228T>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),1217,21,1243,"0,0168946098",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,78","24,43"
"Hotspot, inspected, many artifacts",UPN2_054,2,198266611,C,T,missense_variant(MODERATE|MISSENSE|gGt/gAt|p.Gly742Asp/c.2225G>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|16|T),4017,50,4102,"0,012189176",0,0,0,0,1,0,0,1,2,NO,NO,COSM145923,"haematopoietic_and_lymphoid_tissue, kidney, lung","43, 1, 1",NO,NO,NO,"1,65E-005",NO,NO,"-4,28",Deleterious,"0,074",Tolerated,"32,48","33,64"
"low bq, low freq, many artifacts, many samples",UPN2_003,2,198266709,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys741Asn/c.2223G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),2345,26,2374,"0,0109519798",0,0,0,0,1,0,0,0,1,NO,NO,COSM1159841,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-4,55",Deleterious,1,Damaging,"32,5","16,54"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,198266709,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys741Asn/c.2223G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),12630,142,12799,"0,0110946168",0,0,0,0,1,0,0,0,1,NO,NO,COSM1159841,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-4,55",Deleterious,1,Damaging,"31,45","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,198266709,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys741Asn/c.2223G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),4203,50,4292,"0,0116495806",0,0,0,0,1,0,0,0,1,NO,NO,COSM1159841,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-4,55",Deleterious,1,Damaging,"31,41","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,198266709,C,A,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys741Asn/c.2223G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),14907,173,15134,"0,0114312145",0,0,0,0,1,0,0,0,1,NO,NO,COSM1159841,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-4,55",Deleterious,1,Damaging,"31,28","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,198266709,C,A,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys741Asn/c.2223G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),14232,146,14423,"0,0101227207",0,0,0,0,1,0,0,0,1,NO,NO,COSM1159841,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-4,55",Deleterious,1,Damaging,"31,09","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,198266709,C,A,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys741Asn/c.2223G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),21190,243,21503,"0,0113007487",0,0,0,0,1,0,0,0,1,NO,NO,COSM1159841,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-4,55",Deleterious,1,Damaging,"31,31","15,8"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,198266709,C,A,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys741Asn/c.2223G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),20234,235,20532,"0,0114455484",0,0,0,0,1,0,0,0,1,NO,NO,COSM1159841,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-4,55",Deleterious,1,Damaging,"31,45","15,7"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,198266709,C,A,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys741Asn/c.2223G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),9528,98,9659,"0,0101459778",0,0,0,0,1,0,0,0,1,NO,NO,COSM1159841,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-4,55",Deleterious,1,Damaging,"31,31","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,198266709,C,A,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys741Asn/c.2223G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),7285,84,7402,"0,0113482842",0,0,0,0,1,0,0,0,1,NO,NO,COSM1159841,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-4,55",Deleterious,1,Damaging,"31,18","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_067,2,198266709,C,A,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys741Asn/c.2223G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),15799,174,16012,"0,0108668499",0,0,0,0,1,0,0,0,1,NO,NO,COSM1159841,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-4,55",Deleterious,1,Damaging,"31,38","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,198266709,C,A,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys741Asn/c.2223G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),7491,93,7602,"0,0122336227",0,0,0,0,1,0,0,0,1,NO,NO,COSM1159841,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-4,55",Deleterious,1,Damaging,"31,29","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,198266709,C,A,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys741Asn/c.2223G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),5333,58,5409,"0,0107228693",0,0,0,0,1,0,0,0,1,NO,NO,COSM1159841,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-4,55",Deleterious,1,Damaging,"31,26","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,198266709,C,A,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys741Asn/c.2223G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),6394,68,6487,"0,0104825035",0,0,0,0,1,0,0,0,1,NO,NO,COSM1159841,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-4,55",Deleterious,1,Damaging,"31,33","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,198266709,C,A,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys741Asn/c.2223G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),8473,98,8602,"0,0113926994",0,0,0,0,1,0,0,0,1,NO,NO,COSM1159841,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-4,55",Deleterious,1,Damaging,"31,26","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,198266709,C,A,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys741Asn/c.2223G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),5460,65,5551,"0,0117096019",0,0,0,0,1,0,0,0,1,NO,NO,COSM1159841,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-4,55",Deleterious,1,Damaging,"31,41","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,198266709,C,A,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys741Asn/c.2223G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),6318,77,6421,"0,0119919016",0,0,0,0,1,0,0,0,1,NO,NO,COSM1159841,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-4,55",Deleterious,1,Damaging,"31,47","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,198266709,C,A,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys741Asn/c.2223G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),9827,104,9970,"0,0104312939",0,0,0,0,1,0,0,0,1,NO,NO,COSM1159841,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-4,55",Deleterious,1,Damaging,"31,32","14,42"
"low bq, low freq, many artifacts",UPN2_086,2,198266709,C,A,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys741Asn/c.2223G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),7693,84,7808,"0,0107581967",0,0,0,0,1,0,0,0,1,NO,NO,COSM1159841,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-4,55",Deleterious,1,Damaging,"31,34","14,26"
"low bq, low freq, many artifacts",UPN2_047,2,198266721,T,A,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln737His/c.2211A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),15422,157,15618,"0,0100525035",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,129,Tolerated,"34,51","22,08"
"low bq, low freq, many artifacts, many samples",UPN2_004,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),3318,40,3365,"0,0118870728",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"31,6","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),14557,190,14783,"0,012852601",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,91","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),12607,158,12793,"0,0123505042",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,85","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),15455,181,15667,"0,0115529457",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,73","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),18011,201,18257,"0,0110094758",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,75","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),15377,186,15614,"0,0119123863",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,87","16,27"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),10541,141,10708,"0,0131677251",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,77","15,92"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),14901,187,15125,"0,0123636364",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,68","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),13919,176,14117,"0,0124672381",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,83","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),14207,157,14411,"0,0108944556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,51","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),18467,229,18751,"0,012212682",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,6","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),13227,137,13402,"0,0102223549",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,58","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),18324,208,18578,"0,0111960383",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,72","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),21200,243,21487,"0,0113091637",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,79","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),20214,251,20520,"0,0122319688",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,87","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),5097,58,5163,"0,0112337788",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,76","15,45"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),9238,127,9382,"0,0135365594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,72","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_013,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),6730,72,6816,"0,0105633803",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"31,9","15,17"
"low bq, low freq, many artifacts, many samples",UPN2_091,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),7501,76,7590,"0,0100131752",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,99","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),9511,118,9654,"0,0122229128",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,79","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),7661,96,7782,"0,0123361604",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,55","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),9068,122,9212,"0,0132435953",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,82","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),5357,67,5438,"0,0123207061",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,71","15,66"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),7276,104,7395,"0,0140635565",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,53","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_066,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),13538,155,13723,"0,0112949064",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,61","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_067,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),15737,229,16000,"0,0143125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,68","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),11651,167,11851,"0,0140916378",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,65","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),12344,180,12549,"0,0143437724",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,56","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),7459,110,7587,"0,0144984842",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,62","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),5326,66,5406,"0,012208657",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,6","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),6378,89,6484,"0,013726095",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,66","15,37"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),5995,81,6085,"0,0133114215",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,61","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),7201,105,7328,"0,0143286026",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,71","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),9515,129,9669,"0,0133416072",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,8","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),9287,121,9428,"0,0128341112",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,67","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),10526,124,10692,"0,011597456",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,58","15,56"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),8448,103,8593,"0,0119865006",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,71","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),5478,56,5546,"0,0100973675",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,8","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),7602,115,7738,"0,0148617214",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,81","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),6319,82,6414,"0,0127845338",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,89","15,71"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),12365,162,12556,"0,0129021982",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,65","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),12502,187,12718,"0,0147035697",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,71","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),12448,167,12646,"0,0132057568",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,73","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),9817,126,9963,"0,0126467931",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,7","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_086,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),7671,106,7800,"0,0135897436",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,73","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_087,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),12665,189,12898,"0,0146534346",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,73","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_088,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),10605,123,10743,"0,0114493158",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,91","15,78"
"low bq, low freq, many artifacts, many samples",UPN2_099,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),5095,55,5158,"0,0106630477",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"30,78","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_108,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),10737,111,10865,"0,0102162908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"31,03","14,5"
"low bq, low freq, many artifacts",UPN2_110,2,198266732,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly734Cys/c.2200G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),10560,113,10686,"0,0105745836",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,0,Damaging,"31,01","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,198266735,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys733*/c.2197A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),12605,131,12794,"0,0102391746",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,65","19,01"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,198266735,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys733*/c.2197A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),4232,43,4288,"0,0100279851",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,41","20,07"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,198266735,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys733*/c.2197A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),14886,157,15122,"0,0103822246",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,41","18,35"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,198266747,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys729*/c.2185A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),15900,170,16163,"0,0105178494",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,47","18,08"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,198266747,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys729*/c.2185A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),18600,191,18857,"0,0101288646",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,47","18,74"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,198266747,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys729*/c.2185A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),15799,161,16060,"0,0100249066",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,51","17,01"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,198266747,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys729*/c.2185A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),15247,161,15488,"0,0103951446",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,42","16,88"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,198266747,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys729*/c.2185A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),19057,206,19375,"0,0106322581",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,39","19,55"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,198266747,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys729*/c.2185A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),18874,209,19188,"0,0108922243",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,53","17,17"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,198266747,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys729*/c.2185A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),21834,258,22194,"0,0116247634",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,58","18,41"
"low bq, low freq, many artifacts",UPN2_058,2,198266747,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys729*/c.2185A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),20970,230,21283,"0,0108067472",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,56","19,96"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,198266748,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu728Phe/c.2184A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),29295,338,29750,"0,0113613445",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,69",Deleterious,1,Damaging,"27,8","18,04"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,198266748,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu728Phe/c.2184A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),25297,321,25706,"0,012487357",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,69",Deleterious,1,Damaging,"27,69","17,18"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,198266748,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu728Phe/c.2184A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),8515,92,8646,"0,0106407587",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,69",Deleterious,1,Damaging,"27,77","17,08"
"low bq, low freq, many artifacts, many samples",UPN2_005,2,198266748,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu728Phe/c.2184A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),6564,67,6642,"0,0100873231",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,69",Deleterious,1,Damaging,"28,4","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,198266748,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu728Phe/c.2184A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),30922,379,31399,"0,0120704481",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,69",Deleterious,1,Damaging,"27,86","17,61"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,198266748,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu728Phe/c.2184A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),36120,405,36678,"0,0110420416",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,69",Deleterious,1,Damaging,"27,79","16,27"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,198266748,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu728Phe/c.2184A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),31019,355,31452,"0,0112870406",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,69",Deleterious,1,Damaging,"27,72","17,46"
"low bq, low freq, many artifacts, many samples",UPN2_006,2,198266748,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu728Phe/c.2184A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),21597,219,21861,"0,01001784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,69",Deleterious,1,Damaging,"28,44","18,51"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,198266748,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu728Phe/c.2184A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),21257,223,21535,"0,0103552357",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,69",Deleterious,1,Damaging,"27,83","16,75"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,198266748,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu728Phe/c.2184A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),29935,312,30356,"0,010278034",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,69",Deleterious,1,Damaging,"27,68","16,26"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,198266748,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu728Phe/c.2184A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),27881,322,28295,"0,0113801025",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,69",Deleterious,1,Damaging,"27,76","15,73"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,198266748,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu728Phe/c.2184A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),28395,315,28812,"0,0109329446",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,69",Deleterious,1,Damaging,"27,82","16,31"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,198266748,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu728Phe/c.2184A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),37012,395,37532,"0,0105243526",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,69",Deleterious,1,Damaging,"27,77","17,86"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,198266748,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu728Phe/c.2184A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),26458,321,26870,"0,0119464086",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,69",Deleterious,1,Damaging,"27,8","16,71"
"low bq, low freq, many artifacts, many samples",UPN2_011,2,198266748,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu728Phe/c.2184A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),46681,494,47312,"0,0104413257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,69",Deleterious,1,Damaging,"28,38","18,06"
"low bq, low freq, many artifacts, many samples",UPN2_056,2,198266748,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu728Phe/c.2184A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),3348,37,3396,"0,0108951708",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,69",Deleterious,1,Damaging,"27,7","15,78"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,198266748,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu728Phe/c.2184A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),42605,472,43205,"0,0109246615",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,69",Deleterious,1,Damaging,"27,76","16,38"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,198266748,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu728Phe/c.2184A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),40696,512,41366,"0,0123773147",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,69",Deleterious,1,Damaging,"27,74","17,58"
"low bq, low freq, many artifacts",UPN2_012,2,198266748,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu728Phe/c.2184A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),23929,243,24214,"0,0100355166",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,69",Deleterious,1,Damaging,"28,45","19,44"
"low freq, many artifacts",UPN2_048,2,198266771,T,C,missense_variant(MODERATE|MISSENSE|Atc/Gtc|p.Ile721Val/c.2161A>G|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|C),1874,33,1919,"0,0171964565",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,98",Neutral,"0,002",Damaging,"32,69","32,15"
"low bq, low freq, many artifacts, many samples",UPN2_048,2,198266774,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly720Cys/c.2158G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),1892,24,1917,"0,0125195618",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,79",Deleterious,0,Damaging,"31,05","15,5"
"low bq, low freq, many artifacts, many samples",UPN2_056,2,198266774,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly720Cys/c.2158G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),3398,37,3438,"0,010762071",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,79",Deleterious,0,Damaging,"30,88",14
"low bq, low freq, many artifacts, many samples",UPN2_001,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),17671,249,17944,"0,0138765047",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"31,57","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_014,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),23171,288,23528,"0,0122407344",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"28,93","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_015,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),30723,349,31186,"0,011190919",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"28,78","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_016,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),15989,207,16251,"0,0127376777",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"29,05","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_017,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),11026,132,11202,"0,0117836101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"28,82","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_018,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),16584,195,16841,"0,0115788849",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"28,76","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_019,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),18536,218,18794,"0,0115994466",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"28,79","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_020,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),15972,198,16229,"0,012200382",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"28,87","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_021,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),17595,215,17864,"0,0120353784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"28,97","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_002,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),23610,301,23950,"0,0125678497",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"31,54","14,07"
"low bq, low freq, many artifacts, many samples",UPN2_003,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),4669,58,4734,"0,0122517955",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"31,4","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_022,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),25636,286,26017,"0,0109928124",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"28,84","14,13"
"low bq, low freq, many artifacts, many samples",UPN2_023,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),26825,303,27228,"0,0111282503",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"28,81","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_024,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),12068,154,12284,"0,012536633",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"28,92","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_025,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),27849,343,28264,"0,0121355788",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,29,"14,53"
"low bq, low freq, many artifacts, many samples",UPN2_026,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),29177,299,29586,"0,0101061313",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"28,82","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_004,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),6661,84,6751,"0,0124426011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"31,33","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_027,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),31585,351,32075,"0,0109431021",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"28,83","14,29"
"low bq, many samples",UPN2_089,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),18139,527,18732,"0,028133675",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"29,54","14,92"
"low bq, many samples",UPN2_042,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),28678,703,29543,"0,023795823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"28,62","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_028,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),23037,279,23399,"0,0119235865",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"28,78","14,61"
"low bq, many samples",UPN2_043,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),24752,648,25582,"0,0253303104",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"28,75","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),8347,180,8585,"0,0209668026",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"28,4","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_029,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),28396,342,28857,"0,0118515438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"28,82","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_030,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),26505,329,26939,"0,012212777",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"28,84","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_031,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),15412,206,15679,"0,013138593",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"28,86","14,1"
"low bq, low freq, many artifacts, many samples",UPN2_005,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),6545,92,6646,"0,013842913",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"31,49","14,22"
"low bq, many samples",UPN2_045,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),30343,732,31312,"0,0233776188",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"28,55","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_032,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),11153,122,11311,"0,0107859606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"28,82","14,76"
"low bq, many samples",UPN2_046,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),35431,831,36498,"0,0227683709",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"28,6","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_033,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),19659,251,19976,"0,0125650781",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"29,04","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_034,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),8270,96,8389,"0,011443557",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"28,72","14,3"
"low bq, many samples",UPN2_047,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),30299,694,31181,"0,0222571438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"28,62","14,37"
"low bq, many samples",UPN2_048,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),1836,56,1902,"0,0294426919",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"28,73","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_035,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),25368,292,25739,"0,0113446521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"28,91","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_036,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),29098,332,29513,"0,01124928",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"28,91","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_006,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),21434,292,21768,"0,013414186",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"31,54","14,54"
"low bq, many samples",UPN2_049,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),20738,530,21411,"0,0247536313",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"28,56","14,55"
"low bq, many samples",UPN2_050,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),29266,717,30218,"0,0237275796",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"28,49","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_037,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),34541,379,35066,"0,0108081903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"28,75","14,39"
"low bq, many samples",UPN2_051,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),27356,683,28221,"0,0242018355",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"28,69","14,5"
"low bq, many samples",UPN2_052,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),27929,654,28798,"0,0227099104",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"28,43","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_038,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),43415,520,44114,"0,0117876411",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"28,76","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_039,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),17809,192,18094,"0,0106112523",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"28,68","14,28"
"low bq, many samples",UPN2_053,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),36320,876,37429,"0,0234043122",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"28,5","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),26006,576,26767,"0,0215190346",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"28,56","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_007,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),50510,741,51357,"0,0144284129",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"31,68","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_008,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),65020,942,66073,"0,0142569582",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"31,54","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_009,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),55543,746,56377,"0,0132323465",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"31,56","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_010,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),40072,519,40680,"0,0127581121",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"31,58","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_011,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),46733,654,47461,"0,0137797349",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"31,62","14,19"
"low bq, many samples",UPN2_055,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),36006,889,37117,"0,0239512892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"28,62","14,34"
"low bq, many samples",UPN2_056,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),3320,80,3421,"0,0233849752",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"28,46","15,15"
"low bq, many samples",UPN2_090,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),15280,439,15772,"0,0278341364",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"29,57","14,55"
"low bq, many samples",UPN2_057,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),41691,1023,42946,"0,0238206119",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"28,66","14,32"
"low bq, many samples",UPN2_058,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),39775,1072,41087,"0,0260909777",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"28,77","14,54"
"low bq, many samples",UPN2_059,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),10000,298,10348,"0,0287978353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"30,32","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_012,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),23786,347,24166,"0,0143590168",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"31,57","14,71"
"low bq, many samples",UPN2_060,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),18101,497,18687,"0,0265960293",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"30,23","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_040,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),15778,167,16006,"0,0104335874",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"28,8","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_013,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),13418,186,13638,"0,0136383634",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"31,6","14,48"
"low bq, many samples",UPN2_091,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),14707,441,15194,"0,029024615",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"29,69","14,69"
"low bq, many samples",UPN2_092,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),11346,325,11712,"0,0277493169",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"29,6","14,45"
"low bq, many samples",UPN2_093,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),11788,364,12194,"0,0298507463",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"29,76","15,11"
"low bq, many samples",UPN2_061,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),18655,466,19267,"0,0241864328",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"30,25","14,43"
"low bq, many samples",UPN2_062,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),15095,396,15564,"0,0254433308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"30,23","14,65"
"low bq, many samples",UPN2_063,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),17854,452,18393,"0,0245745664",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"30,34","14,78"
"low bq, many samples",UPN2_064,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),10511,279,10836,"0,0257475083",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"30,32","14,47"
"low bq, many samples",UPN2_065,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),14264,410,14750,"0,0277966102",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"30,31","14,54"
"low bq, many samples",UPN2_066,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),26593,703,27417,"0,0256410256",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"30,33","14,83"
"low bq, many samples",UPN2_067,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),30987,839,31955,"0,026255672",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"30,18","15,02"
"low bq, many samples",UPN2_068,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),22933,615,23675,"0,0259767687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"30,19","14,55"
"low bq, many samples",UPN2_069,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),24303,706,25132,"0,028091676",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"30,15","14,5"
"low bq, many samples",UPN2_070,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),14669,392,15144,"0,0258848389",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"30,21","14,52"
"low bq, many samples",UPN2_071,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),10446,301,10803,"0,0278626308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"30,35","14,53"
"low bq, many samples",UPN2_072,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),12507,353,12934,"0,0272924076",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"30,35","14,59"
"low bq, many samples",UPN2_073,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),11754,320,12141,"0,0263569722",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"30,24","14,67"
"low bq, many samples",UPN2_074,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),14133,394,14617,"0,0269549155",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"30,23","14,52"
"low bq, many samples",UPN2_075,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),18698,530,19314,"0,0274412343",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"30,32","14,62"
"low bq, many samples",UPN2_076,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),18298,453,18826,"0,0240624668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"30,13","14,77"
"low bq, many samples",UPN2_077,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),20676,568,21349,"0,0266054616",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"30,16","14,45"
"low bq, many samples",UPN2_078,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),16637,434,17151,"0,025304647",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"30,19","14,47"
"low bq, many samples",UPN2_079,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),10737,263,11064,"0,0237707881",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"30,15","14,66"
"low bq, many samples",UPN2_080,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),14998,435,15489,"0,028084447",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"30,27","14,6"
"low bq, many samples",UPN2_081,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),12392,373,12813,"0,0291110591",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"30,27","14,39"
"low bq, many samples",UPN2_082,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),24276,692,25094,"0,0275763131",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"30,22","14,43"
"low bq, many samples",UPN2_083,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),24656,630,25429,"0,0247748633",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"30,2","14,74"
"low bq, many samples",UPN2_084,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),24528,655,25322,"0,0258668352",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"30,23","14,73"
"low bq, many samples",UPN2_085,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),19239,557,19885,"0,0280110636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"30,34","14,66"
"low bq, many samples",UPN2_086,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),15122,416,15611,"0,0266478765",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"30,26","14,44"
"low bq, many samples",UPN2_087,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),24965,707,25786,"0,0274179787",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"30,24","14,55"
"low bq, many samples",UPN2_088,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),20846,571,21510,"0,0265457927",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"30,41","14,6"
"low bq, many samples",UPN2_094,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),15425,423,15923,"0,0265653457",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"29,55","14,88"
"low bq, many samples",UPN2_095,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),16543,474,17126,"0,0276772159",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"29,54","14,79"
"low bq, many samples",UPN2_096,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),17080,467,17619,"0,026505477",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"29,55","14,53"
"low bq, many samples",UPN2_097,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),17059,512,17648,"0,029011786",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"29,59","14,49"
"low bq, many samples",UPN2_098,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),15570,468,16096,"0,0290755467",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"29,58","14,49"
"low bq, many samples",UPN2_099,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),9992,281,10317,"0,0272365998",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"29,6","15,01"
"low bq, many samples",UPN2_100,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),12852,411,13300,"0,0309022556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"29,8","14,89"
"low bq, many samples",UPN2_101,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),16402,475,16946,"0,0280302136",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"29,52","14,87"
"low bq, many samples",UPN2_102,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),17854,512,18441,"0,027764221",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"29,5","14,59"
"low bq, many samples",UPN2_103,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),15348,401,15808,"0,0253669028",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"29,49","14,77"
"low bq, many samples",UPN2_104,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),18809,532,19406,"0,0274142018",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"29,57","14,81"
"low bq, many samples",UPN2_105,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),14758,443,15270,"0,0290111329",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"29,61","14,47"
"low bq, many samples",UPN2_106,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),16987,528,17587,"0,0300221755",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"29,59","14,56"
"low bq, many samples",UPN2_107,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),30348,853,31334,"0,027222825",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"29,58","14,67"
"low bq, many samples",UPN2_108,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),20999,612,21697,"0,0282066645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"29,64","14,57"
"low bq, many samples",UPN2_109,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),21787,621,22475,"0,0276307008",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"29,56","14,62"
"low bq, many samples",UPN2_110,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),20664,593,21334,"0,0277960064",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"29,56","14,52"
low bq,UPN2_111,2,198266786,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala716Ser/c.2146G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|A),21106,569,21756,"0,0261537047",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,532,Tolerated,"29,54","14,55"
"low freq, many artifacts",UPN2_056,2,198266797,A,C,missense_variant(MODERATE|MISSENSE|tTg/tGg|p.Leu712Trp/c.2135T>G|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|C),1702,23,1743,"0,0131956397",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"35,02","33,7"
"Hotspot, leakage, inspected",UPN2_007,2,198266834,T,C,missense_variant(MODERATE|MISSENSE|Aaa/Gaa|p.Lys700Glu/c.2098A>G|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|C),25502,494,26019,"0,0189861255",0,0,0,0,1,0,0,1,2,NO,0,COSM84677,"breast, central_nervous_system, eye, haematopoietic_and_lymphoid_tissue, kidney, NS, oesophagus, pancreas, prostate","14, 2, 1, 395, 1, 515, 1, 13, 4",NO,NO,NO,"0,0002306",NO,NO,"-3,91",Deleterious,"0,004",Damaging,"35,4","35,16"
"Hotspot, leakage, inspected",UPN2_094,2,198266834,T,C,missense_variant(MODERATE|MISSENSE|Aaa/Gaa|p.Lys700Glu/c.2098A>G|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|C),7820,227,8055,"0,0281812539",0,0,0,0,1,0,0,1,2,NO,0,COSM84677,"breast, central_nervous_system, eye, haematopoietic_and_lymphoid_tissue, kidney, NS, oesophagus, pancreas, prostate","14, 2, 1, 395, 1, 515, 1, 13, 4",NO,NO,NO,"0,0002306",NO,NO,"-3,91",Deleterious,"0,004",Damaging,"35,48","35,19"
"low freq, many artifacts",UPN2_056,2,198266836,T,C,missense_variant(MODERATE|MISSENSE|cAg/cGg|p.Gln699Arg/c.2096A>G|1304|SF3B1|protein_coding|CODING|ENST00000335508|15|C),1718,24,1743,"0,0137693632",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,"0,069",Tolerated,"34,77","35,46"
"low bq, low freq, many artifacts, many samples",UPN2_089,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3101,61,3168,"0,0192550505",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,3","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4056,58,4133,"0,0140333898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,91","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3466,38,3537,"0,010743568",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,89","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),5260,59,5342,"0,0110445526",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,88",14
"low bq, low freq, many artifacts, many samples",UPN2_047,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),5096,62,5165,"0,0120038722",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,14","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2166,27,2207,"0,0122338015",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,02",14
"low bq, low freq, many artifacts, many samples",UPN2_050,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2897,41,2951,"0,0138935954",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,62","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4057,45,4119,"0,0109249818",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,93",14
"low bq, low freq, many artifacts, many samples",UPN2_052,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4417,54,4505,"0,0119866815",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,74",14
"low bq, low freq, many artifacts, many samples",UPN2_054,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3703,51,3781,"0,0134884951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,74",14
"low bq, many samples",UPN2_090,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2438,55,2493,"0,022061773",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,46",14
"low bq, low freq, many artifacts, many samples",UPN2_057,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4473,61,4542,"0,013430207",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,93","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4299,54,4383,"0,0123203285",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,04","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4802,107,4927,"0,0217170692",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,14","14,55"
"low bq, many samples",UPN2_060,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4611,106,4767,"0,0222362073",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,01","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_091,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2539,53,2600,"0,0203846154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,59","14,34"
"low bq, many samples",UPN2_092,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1898,44,1945,"0,022622108",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,75","14,3"
"low bq, many samples",UPN2_093,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1475,41,1520,"0,0269736842",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,65",14
"low bq, many samples",UPN2_061,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2756,68,2836,"0,023977433",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,33","14,85"
"low bq, many samples",UPN2_062,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2945,71,3029,"0,0234400792",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,92","14,75"
"low bq, many samples",UPN2_063,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3246,94,3351,"0,028051328",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,36","14,66"
"low bq, many samples",UPN2_064,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2428,57,2494,"0,0228548516",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,78","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4682,90,4784,"0,018812709",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,08","15,37"
"low bq, many samples",UPN2_066,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),7664,184,7870,"0,0233799238",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,19","14,67"
"low bq, many samples",UPN2_067,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),7730,191,7962,"0,0239889475",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,07","14,32"
"low bq, many samples",UPN2_068,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4757,124,4907,"0,0252700224",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,29,"14,31"
"low bq, many samples",UPN2_069,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6801,168,7002,"0,0239931448",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,14","14,61"
"low bq, many samples",UPN2_070,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3616,110,3738,"0,0294275013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,17","14,4"
"low bq, many samples",UPN2_071,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4779,115,4915,"0,023397762",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,41","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3360,69,3440,"0,0200581395",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,17","14,19"
"low bq, many samples",UPN2_073,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3719,105,3843,"0,0273224044",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,18","14,71"
"low bq, many samples",UPN2_074,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4386,102,4508,"0,0226264419",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,04","14,18"
"low bq, many samples",UPN2_075,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),7232,175,7432,"0,0235468245",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,21","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4093,91,4208,"0,0216254753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,95","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4490,100,4605,"0,0217155266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,16","14,71"
"low bq, many samples",UPN2_078,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4704,132,4849,"0,0272221077",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,9","14,33"
"low bq, many samples",UPN2_079,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3511,89,3618,"0,0245992261",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,22","14,74"
"low bq, many samples",UPN2_080,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3725,93,3831,"0,024275646",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,14","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4762,98,4879,"0,0200860832",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,52","14,27"
"low bq, many samples",UPN2_082,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),7581,197,7822,"0,0251853746",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,15","14,53"
"low bq, many samples",UPN2_083,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6913,170,7110,"0,0239099859",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,29,"14,18"
"low bq, many samples",UPN2_084,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4308,118,4437,"0,0265945459",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,91","14,6"
"low bq, many samples",UPN2_085,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6739,163,6936,"0,0235005767",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,07","14,56"
"low bq, many samples",UPN2_086,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6255,157,6432,"0,024409204",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,14","14,44"
"low bq, many samples",UPN2_087,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),9263,225,9537,"0,0235923246",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,15","14,43"
"low bq, many samples",UPN2_088,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),7408,193,7633,"0,0252849469",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,21","14,47"
"low bq, many samples",UPN2_094,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2976,83,3075,"0,0269918699",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,47",14
"low bq, many samples",UPN2_095,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2544,61,2617,"0,0233091326",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,64","14,3"
"low bq, many samples",UPN2_096,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3078,82,3166,"0,0259001895",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,76",14
"low bq, low freq, many artifacts, many samples",UPN2_097,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2931,63,2999,"0,0210070023",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,41",14
"low bq, many samples",UPN2_098,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2448,60,2518,"0,0238284353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,66","14,52"
"low bq, many samples",UPN2_099,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1729,52,1785,"0,0291316527",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,21","14,25"
"low bq, many samples",UPN2_100,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2524,67,2595,"0,0258188825",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,33",14
"low bq, low freq, many artifacts, many samples",UPN2_101,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2152,41,2202,"0,0186194369",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,25",14
"low bq, many samples",UPN2_102,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2509,66,2578,"0,0256012413",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,18","14,27"
"low bq, many samples",UPN2_103,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2816,72,2899,"0,0248361504",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,06","14,18"
"low bq, low freq, many artifacts, many samples",UPN2_104,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3499,77,3587,"0,0214664065",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,33","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_105,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2260,49,2312,"0,0211937716",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,95",14
"low bq, many samples",UPN2_106,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3432,98,3535,"0,0277227723",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,63","14,18"
"low bq, many samples",UPN2_107,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),5402,149,5562,"0,0267889248",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,81",14
"low bq, many samples",UPN2_109,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4268,108,4389,"0,024606972",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,37","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_110,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4460,99,4572,"0,0216535433",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,61","14,4"
low bq,UPN2_111,2,198267279,C,A,splice_donor_variant+intron_variant(HIGH|||c.2077+1G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3112,81,3201,"0,0253045923",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,62","14,65"
"low bq, many samples",UPN2_001,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1470,88,1561,"0,0563741192",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"27,82","14,3"
"low bq, many samples",UPN2_014,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3572,166,3746,"0,0443139349",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"27,34","14,16"
"low bq, many samples",UPN2_015,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4483,217,4711,"0,0460624071",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"27,42","14,12"
"low bq, many samples",UPN2_016,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3623,145,3775,"0,038410596",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"27,33",14
"low bq, many samples",UPN2_017,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2259,109,2373,"0,0459334176",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"27,38","14,12"
"low bq, many samples",UPN2_018,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3641,174,3822,"0,0455259027",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"27,22",14
"low bq, many samples",UPN2_019,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3867,168,4038,"0,0416047548",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"27,22","14,37"
"low bq, many samples",UPN2_020,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2703,130,2838,"0,0458069063",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"27,37",14
"low bq, many samples",UPN2_021,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3844,188,4044,"0,0464886251",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"27,17","14,21"
"low bq, many samples",UPN2_002,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2460,128,2590,"0,0494208494",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"27,82","14,41"
"low bq, many samples",UPN2_003,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),450,20,471,"0,042462845",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"28,1","14,9"
"low bq, many samples",UPN2_022,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4741,216,4966,"0,0434957712",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"27,22",14
"low bq, many samples",UPN2_023,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4667,240,4912,"0,0488599349",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"27,11","14,16"
"low bq, many samples",UPN2_024,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2202,94,2299,"0,0408873423",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"27,29","14,56"
"low bq, many samples",UPN2_025,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6802,286,7100,"0,0402816901",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"27,08","14,05"
"low bq, many samples",UPN2_026,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6394,261,6659,"0,0391950743",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"27,21","14,17"
"low bq, many samples",UPN2_027,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),7307,310,7632,"0,0406184486",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"27,16","14,04"
"low bq, many samples",UPN2_089,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2875,269,3150,"0,0853968254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"29,65","14,26"
"low bq, bad alignment, many samples",UPN2_042,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3823,283,4118,"0,0687226809",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"26,42","14,74"
"low bq, many samples",UPN2_028,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3968,141,4113,"0,0342815463",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"27,14",14
"low bq, bad alignment, many samples",UPN2_043,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3116,226,3350,"0,0674626866",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"26,74","14,23"
"low bq, many samples",UPN2_044,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),974,62,1037,"0,0597878496",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"27,09",14
"low bq, many samples",UPN2_029,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4848,195,5049,"0,0386215092",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"27,19",14
"low bq, many samples",UPN2_030,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4991,240,5238,"0,0458190149",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"27,15",14
"low bq, many samples",UPN2_031,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3269,144,3417,"0,04214223",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"27,21","14,09"
"low bq, many samples",UPN2_005,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),528,29,558,"0,0519713262",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"28,03",14
"low bq, bad alignment, many samples",UPN2_045,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3284,223,3525,"0,0632624113",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"26,85","14,45"
"low bq, many samples",UPN2_032,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1671,67,1745,"0,0383954155",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"27,35",14
"low bq, bad alignment, many samples",UPN2_046,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4947,361,5325,"0,0677934272",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"26,55","14,12"
"low bq, many samples",UPN2_033,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4215,181,4403,"0,0411083352",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"27,13","14,07"
"low bq, bad alignment, many samples",UPN2_034,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1530,62,1594,"0,0388958595",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"26,94",14
"low bq, bad alignment, many samples",UPN2_047,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4815,323,5149,"0,0627306273",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"26,79","14,35"
"low bq, many samples",UPN2_048,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),798,54,853,"0,0633059789",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"27,08",14
"low bq, many samples",UPN2_035,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3699,144,3851,"0,037392885",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"27,24","14,09"
"low bq, many samples",UPN2_036,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3627,140,3780,"0,037037037",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"27,2",14
"low bq, many samples",UPN2_006,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1864,96,1960,"0,0489795918",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"27,57","14,19"
"low bq, bad alignment, many samples",UPN2_049,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2041,148,2197,"0,0673645881",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"26,44","14,18"
"low bq, bad alignment, many samples",UPN2_050,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2724,193,2936,"0,0657356948",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"26,8","14,2"
"low bq, many samples",UPN2_037,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6545,267,6825,"0,0391208791",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"27,22","14,22"
"low bq, bad alignment, many samples",UPN2_051,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3826,262,4104,"0,0638401559",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"26,6","14,1"
"low bq, bad alignment, many samples",UPN2_052,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4181,276,4480,"0,0616071429",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"26,27","14,3"
"low bq, many samples",UPN2_038,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),9284,381,9684,"0,0393432466",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"27,13","14,05"
"low bq, many samples",UPN2_039,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3050,139,3195,"0,0435054773",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"27,37",14
"low bq, bad alignment, many samples",UPN2_053,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4257,294,4565,"0,0644030668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"26,47","14,51"
"low bq, bad alignment, many samples",UPN2_054,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3507,234,3764,"0,0621679065",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"26,3","14,21"
"low bq, many samples",UPN2_007,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4803,227,5041,"0,0450307479",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"27,75","14,45"
"low bq, many samples",UPN2_008,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6299,368,6677,"0,0551145724",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"27,88","14,23"
"low bq, many samples",UPN2_009,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4363,275,4650,"0,0591397849",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"27,97","14,65"
"low bq, many samples",UPN2_010,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3359,205,3569,"0,0574390586",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"27,85","14,1"
"low bq, many samples",UPN2_011,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4174,243,4423,"0,0549400859",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"27,68","14,2"
"low bq, bad alignment, many samples",UPN2_055,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4433,290,4748,"0,0610783488",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"26,37","14,77"
"low bq, bad alignment, many samples",UPN2_056,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),651,43,695,"0,0618705036",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"26,91",14
"low bq, many samples",UPN2_090,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2280,196,2479,"0,0790641388",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"29,55","14,56"
"low bq, bad alignment, many samples",UPN2_057,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4225,277,4520,"0,0612831858",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"26,58","14,33"
"low bq, bad alignment, many samples",UPN2_058,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4035,311,4358,"0,0713630106",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"26,83","14,38"
"low bq, many samples",UPN2_059,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4527,364,4897,"0,0743312232",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"28,82","14,42"
"low bq, many samples",UPN2_012,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),986,58,1044,"0,0555555556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"27,81","14,66"
"low bq, many samples",UPN2_060,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4395,332,4742,"0,0700126529",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"28,78","14,61"
"low bq, many samples",UPN2_040,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1910,99,2015,"0,0491315136",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"27,34","14,44"
"low bq, many samples",UPN2_013,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1102,72,1176,"0,0612244898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"27,9",14
"low bq, many samples",UPN2_091,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2348,231,2583,"0,0894308943",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"30,23","14,84"
"low bq, many samples",UPN2_092,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1783,143,1929,"0,0741316744",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"30,26","14,69"
"low bq, many samples",UPN2_093,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1381,127,1510,"0,0841059603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"29,84","14,31"
"low bq, many samples",UPN2_061,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2597,201,2818,"0,0713271824",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"28,76","14,3"
"low bq, many samples",UPN2_062,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2786,217,3012,"0,0720451527",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"28,39","14,3"
"low bq, many samples",UPN2_063,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3081,240,3332,"0,0720288115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"29,02","14,55"
"low bq, many samples",UPN2_064,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2282,187,2478,"0,0754640839",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"28,77","14,37"
"low bq, many samples",UPN2_065,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4410,323,4749,"0,0680143188",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"28,72","14,65"
"low bq, many samples",UPN2_066,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),7204,596,7822,"0,0761953465",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"28,83","14,56"
"low bq, many samples",UPN2_067,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),7343,535,7900,"0,067721519",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"28,7","14,59"
"low bq, many samples",UPN2_068,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4505,362,4879,"0,0741955319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"28,76","14,69"
"low bq, many samples",UPN2_069,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6464,476,6962,"0,0683711577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"28,82","14,7"
"low bq, many samples",UPN2_070,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3429,266,3706,"0,0717754992",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"28,87","14,8"
"low bq, many samples",UPN2_071,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4545,332,4890,"0,0678936605",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"29,11","14,49"
"low bq, many samples",UPN2_072,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3148,248,3407,"0,072791312",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"28,97","14,93"
"low bq, many samples",UPN2_073,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3527,280,3823,"0,0732409103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"28,98","14,58"
"low bq, many samples",UPN2_074,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4160,303,4475,"0,0677094972",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"28,67","14,5"
"low bq, many samples",UPN2_075,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6859,499,7387,"0,0675511033",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"28,98","14,72"
"low bq, many samples",UPN2_076,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3865,295,4184,"0,0705066922",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"28,74","14,62"
"low bq, many samples",UPN2_077,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4260,300,4570,"0,0656455142",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"28,78","14,28"
"low bq, many samples",UPN2_078,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4452,354,4821,"0,0734287492",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"28,61","14,44"
"low bq, many samples",UPN2_079,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3350,235,3593,"0,0654049541",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"28,81","14,65"
"low bq, many samples",UPN2_080,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3492,294,3798,"0,0774091627",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"29,03","14,72"
"low bq, many samples",UPN2_081,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4484,332,4835,"0,0686659772",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"29,13","15,07"
"low bq, many samples",UPN2_082,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),7206,535,7766,"0,0688900335",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"28,91","14,44"
"low bq, many samples",UPN2_083,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6541,467,7050,"0,0662411348",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"28,66","14,66"
"low bq, many samples",UPN2_084,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4106,283,4403,"0,0642743584",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"28,63","14,6"
"low bq, many samples",UPN2_085,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6398,475,6889,"0,0689505008",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"28,84","14,76"
"low bq, many samples",UPN2_086,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),5933,440,6389,"0,0688683675",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"28,81","14,7"
"low bq, many samples",UPN2_087,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),8791,664,9483,"0,0700200359",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"28,85","14,66"
"low bq, many samples",UPN2_088,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),7006,538,7569,"0,0710794028",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"28,88","15,02"
"low bq, many samples",UPN2_094,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2753,291,3053,"0,0953160825",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"30,23","14,57"
"low bq, many samples",UPN2_095,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2373,225,2600,"0,0865384615",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"30,05","14,68"
"low bq, many samples",UPN2_096,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2887,257,3156,"0,0814321926",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"30,21","14,1"
"low bq, many samples",UPN2_097,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2707,260,2976,"0,0873655914",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"30,09","14,33"
"low bq, many samples",UPN2_098,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2287,216,2506,"0,0861931365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"30,08","14,2"
"low bq, many samples",UPN2_099,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1609,158,1776,"0,088963964",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"29,69","14,55"
"low bq, many samples",UPN2_100,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2347,228,2580,"0,088372093",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"29,72","14,51"
"low bq, many samples",UPN2_101,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1991,188,2190,"0,0858447489",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"29,75","14,48"
"low bq, many samples",UPN2_102,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2355,216,2572,"0,0839813375",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"29,52","14,38"
"low bq, many samples",UPN2_103,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2618,256,2882,"0,0888272033",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"29,65","14,23"
"low bq, many samples",UPN2_104,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3270,288,3565,"0,0807854137",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"29,72","14,35"
"low bq, many samples",UPN2_105,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2118,172,2293,"0,0750109027",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"29,36","14,52"
"low bq, many samples",UPN2_106,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3194,309,3510,"0,088034188",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"30,16","14,24"
"low bq, many samples",UPN2_107,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),5041,477,5536,"0,0861632948",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"30,26","14,52"
"low bq, many samples",UPN2_108,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3898,383,4305,"0,0889663182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"30,19","14,61"
"low bq, many samples",UPN2_109,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3988,380,4373,"0,0868968671",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"29,83","14,58"
"low bq, many samples",UPN2_110,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4137,400,4543,"0,0880475457",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"30,06","14,18"
low bq,UPN2_111,2,198267280,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly693Cys/c.2077G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2907,258,3178,"0,081183134",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,58",Deleterious,44,Damaging,"30,12","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,198267282,T,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|cAt/cTt|p.His692Leu/c.2075A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4820,54,4886,"0,0110519853",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,09",Deleterious,251,Tolerated,"28,93","17,02"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,198267282,T,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|cAt/cTt|p.His692Leu/c.2075A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4647,74,4736,"0,015625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,09",Deleterious,251,Tolerated,"28,85","19,34"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,198267282,T,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|cAt/cTt|p.His692Leu/c.2075A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2776,30,2810,"0,0106761566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,09",Deleterious,251,Tolerated,"28,76","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,198267282,T,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|cAt/cTt|p.His692Leu/c.2075A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2425,43,2475,"0,0173737374",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,09",Deleterious,251,Tolerated,"28,74","16,05"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,198267282,T,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|cAt/cTt|p.His692Leu/c.2075A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4668,62,4745,"0,0130663857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,09",Deleterious,251,Tolerated,"29,2","16,9"
"low bq, low freq, many artifacts, many samples",UPN2_067,2,198267282,T,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|cAt/cTt|p.His692Leu/c.2075A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),7771,82,7881,"0,010404771",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,09",Deleterious,251,Tolerated,"29,03","16,05"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,198267282,T,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|cAt/cTt|p.His692Leu/c.2075A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4789,66,4875,"0,0135384615",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,09",Deleterious,251,Tolerated,"28,89","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,198267282,T,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|cAt/cTt|p.His692Leu/c.2075A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3645,49,3701,"0,013239665",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,09",Deleterious,251,Tolerated,"28,79","17,14"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,198267282,T,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|cAt/cTt|p.His692Leu/c.2075A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4814,52,4879,"0,0106579217",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,09",Deleterious,251,Tolerated,"29,09","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,198267282,T,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|cAt/cTt|p.His692Leu/c.2075A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3346,43,3399,"0,0126507796",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,09",Deleterious,251,Tolerated,"28,98","16,35"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,198267282,T,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|cAt/cTt|p.His692Leu/c.2075A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4400,49,4463,"0,010979162",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,09",Deleterious,251,Tolerated,"29,09","16,16"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,198267282,T,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|cAt/cTt|p.His692Leu/c.2075A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),7277,80,7377,"0,0108445167",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,09",Deleterious,251,Tolerated,"29,26","16,98"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,198267282,T,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|cAt/cTt|p.His692Leu/c.2075A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4125,45,4177,"0,0107732823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,09",Deleterious,251,Tolerated,"28,78","17,22"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,198267282,T,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|cAt/cTt|p.His692Leu/c.2075A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4478,72,4565,"0,0157721796",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,09",Deleterious,251,Tolerated,"29,04","16,58"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,198267282,T,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|cAt/cTt|p.His692Leu/c.2075A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4743,54,4815,"0,0112149533",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,09",Deleterious,251,Tolerated,"28,74","16,94"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,198267282,T,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|cAt/cTt|p.His692Leu/c.2075A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3538,36,3586,"0,0100390407",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,09",Deleterious,251,Tolerated,"29,1","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,198267282,T,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|cAt/cTt|p.His692Leu/c.2075A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),7643,92,7758,"0,0118587265",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,09",Deleterious,251,Tolerated,"28,97","15,39"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,198267282,T,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|cAt/cTt|p.His692Leu/c.2075A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6926,82,7031,"0,0116626369",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,09",Deleterious,251,Tolerated,"28,58","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,198267282,T,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|cAt/cTt|p.His692Leu/c.2075A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6784,71,6881,"0,0103182677",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,09",Deleterious,251,Tolerated,"28,83","15,73"
"low bq, low freq, many artifacts",UPN2_087,2,198267282,T,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|cAt/cTt|p.His692Leu/c.2075A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),9320,117,9464,"0,0123626374",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,09",Deleterious,251,Tolerated,"28,92","18,38"
"low bq, many samples",UPN2_001,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),1504,44,1551,"0,0283687943",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"28,52",14
"low bq, low freq, many artifacts, many samples",UPN2_014,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),3652,71,3728,"0,0190450644",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,78",14
"low bq, low freq, many artifacts, many samples",UPN2_015,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),4606,72,4690,"0,0153518124",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,91",14
"low bq, low freq, many artifacts, many samples",UPN2_016,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),3669,77,3753,"0,0205169198",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"28,2","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_017,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),2325,34,2366,"0,0143702451",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,74",14
"low bq, low freq, many artifacts, many samples",UPN2_018,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),3728,69,3804,"0,0181388013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,74",14
"low bq, low freq, many artifacts, many samples",UPN2_019,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),3946,62,4023,"0,0154113845",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,81",14
"low bq, low freq, many artifacts, many samples",UPN2_020,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),2789,35,2826,"0,0123849965",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,85",14
"low bq, low freq, many artifacts, many samples",UPN2_021,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),3931,85,4030,"0,0210918114",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,8","14,52"
"low bq, many samples",UPN2_002,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),2513,58,2576,"0,022515528",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"28,63",14
"low bq, low freq, many artifacts, many samples",UPN2_022,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),4845,94,4951,"0,0189860634",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,76",14
"low bq, low freq, many artifacts, many samples",UPN2_023,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),4775,97,4887,"0,0198485779",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,92",14
"low bq, low freq, many artifacts, many samples",UPN2_024,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),2242,45,2292,"0,0196335079",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,85",14
"low bq, low freq, many artifacts, many samples",UPN2_025,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),6918,139,7072,"0,0196549774",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,81","14,09"
"low bq, low freq, many artifacts, many samples",UPN2_026,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),6520,99,6637,"0,0149163779",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,78","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_027,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),7479,116,7603,"0,0152571353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,76","14,06"
"low bq, many samples",UPN2_042,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),3981,117,4103,"0,0285157202",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,42","14,11"
"low bq, low freq, many artifacts, many samples",UPN2_028,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),4017,69,4091,"0,0168662919",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,76",14
"low bq, many samples",UPN2_044,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),1003,28,1033,"0,0271055179",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,26",14
"low bq, low freq, many artifacts, many samples",UPN2_029,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),4913,99,5024,"0,019705414",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,9",14
"low bq, low freq, many artifacts, many samples",UPN2_030,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),5115,86,5214,"0,0164940545",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,92",14
"low bq, low freq, many artifacts, many samples",UPN2_031,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),3340,59,3403,"0,0173376433",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,75",14
"low bq, low freq, many artifacts, many samples",UPN2_032,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),1709,26,1737,"0,0149683362",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"28,05",14
"low bq, many samples",UPN2_046,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),5109,180,5308,"0,0339110776",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,44","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_033,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),4305,74,4383,"0,0168834132",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,86",14
"low bq, low freq, many artifacts, many samples",UPN2_034,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),1560,23,1586,"0,0145018916",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,6",14
"low bq, many samples",UPN2_047,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),4950,169,5132,"0,0329306313",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,54","14,24"
"low bq, many samples",UPN2_048,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),814,33,848,"0,0389150943",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,82",14
"low bq, low freq, many artifacts, many samples",UPN2_035,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),3752,72,3832,"0,0187891441",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,96","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_036,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),3685,78,3770,"0,0206896552",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,94",14
"low bq, many samples",UPN2_006,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),1895,54,1952,"0,0276639344",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"28,62",14
"low bq, many samples",UPN2_049,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),2120,67,2193,"0,0305517556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,35","14,39"
"low bq, many samples",UPN2_050,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),2823,96,2924,"0,0328317373",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,36","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_037,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),6676,113,6799,"0,0166200912",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,85","14,06"
"low bq, many samples",UPN2_051,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),3941,140,4085,"0,0342717258",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,4","14,09"
"low bq, low freq, many artifacts, many samples",UPN2_038,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),9472,162,9651,"0,0167858253",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,91","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_039,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),3136,39,3184,"0,0122487437",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,78",14
"low bq, many samples",UPN2_054,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),3612,124,3748,"0,0330843116",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,17","14,15"
"low bq, many samples",UPN2_009,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),4478,129,4612,"0,0279705117",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"28,7","14,05"
"low bq, many samples",UPN2_011,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),4269,125,4398,"0,02842201",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"28,49","14,1"
"low bq, many samples",UPN2_055,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),4564,157,4734,"0,0331643431",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,33","14,2"
"low bq, many samples",UPN2_012,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),992,39,1036,"0,0376447876",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"28,74",14
"low bq, many samples",UPN2_060,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),4534,157,4715,"0,0332979852",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,34",14
"low bq, many samples",UPN2_040,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),1950,51,2007,"0,0254110613",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,93","14,25"
"low bq, many samples",UPN2_013,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),1128,33,1168,"0,0282534247",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"28,66",14
"low bq, many samples",UPN2_091,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),2512,59,2573,"0,0229304314",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"28,59",14
"low bq, many samples",UPN2_092,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),1878,43,1925,"0,0223376623",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"28,75",14
"low bq, many samples",UPN2_093,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),1454,46,1502,"0,0306258322",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"28,47",14
"low bq, bad alignment, many samples",UPN2_062,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),2870,108,2995,"0,0360601002",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"26,97",14
"low bq, many samples",UPN2_063,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),3183,110,3315,"0,0331825038",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,42","14,2"
"low bq, many samples",UPN2_064,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),2386,67,2465,"0,0271805274",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,37",14
"low bq, many samples",UPN2_070,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),3550,115,3681,"0,0312415105",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,22","14,16"
"low bq, many samples",UPN2_071,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),4680,166,4862,"0,0341423283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,44","14,13"
"low bq, many samples",UPN2_072,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),3241,102,3384,"0,030141844",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,37",14
"low bq, many samples",UPN2_074,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),4282,141,4441,"0,0317496059",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,31","14,13"
"low bq, many samples",UPN2_076,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),4006,131,4156,"0,031520693",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,14",14
"low bq, many samples",UPN2_077,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),4368,154,4548,"0,0338610378",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,32","14,13"
"low bq, many samples",UPN2_083,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),6749,212,7007,"0,0302554588",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,26","14,17"
"low bq, many samples",UPN2_088,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),7237,263,7534,"0,0349084152",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"27,54",14
"low bq, many samples",UPN2_099,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),1720,45,1772,"0,0253950339",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,28,14
low bq,UPN2_108,2,198267283,G,T,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His692Asn/c.2074C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),4186,100,4287,"0,0233263354",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,371,Tolerated,"28,59",14
"low bq, many samples",UPN2_001,2,198267285,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu691Val/c.2072A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1504,34,1545,"0,0220064725",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,116,Tolerated,"28,34","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_014,2,198267285,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu691Val/c.2072A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3625,57,3709,"0,0153680237",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,116,Tolerated,"27,83","15,93"
"low bq, low freq, many artifacts, many samples",UPN2_015,2,198267285,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu691Val/c.2072A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4548,95,4665,"0,0203644159",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,116,Tolerated,"27,71","17,16"
"low bq, low freq, many artifacts, many samples",UPN2_016,2,198267285,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu691Val/c.2072A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3666,59,3738,"0,0157838416",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,116,Tolerated,"28,05","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_017,2,198267285,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu691Val/c.2072A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2306,38,2356,"0,0161290323",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,116,Tolerated,"27,61",14
"low bq, low freq, many artifacts, many samples",UPN2_018,2,198267285,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu691Val/c.2072A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3699,77,3787,"0,0203327172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,116,Tolerated,"27,58","16,01"
"low bq, low freq, many artifacts, many samples",UPN2_019,2,198267285,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu691Val/c.2072A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3918,70,4000,"0,0175",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,116,Tolerated,"27,73","15,39"
"low bq, low freq, many artifacts, many samples",UPN2_020,2,198267285,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu691Val/c.2072A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2750,57,2817,"0,0202342918",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,116,Tolerated,"27,93",15
"low bq, low freq, many artifacts, many samples",UPN2_021,2,198267285,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu691Val/c.2072A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3922,73,4012,"0,0181954138",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,116,Tolerated,"27,56","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_002,2,198267285,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu691Val/c.2072A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2512,40,2568,"0,015576324",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,116,Tolerated,"28,46","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_022,2,198267285,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu691Val/c.2072A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4824,76,4932,"0,0154095702",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,116,Tolerated,"27,79","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_023,2,198267285,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu691Val/c.2072A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4759,87,4869,"0,0178681454",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,116,Tolerated,"27,61","15,52"
"low bq, low freq, many artifacts, many samples",UPN2_024,2,198267285,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu691Val/c.2072A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2233,38,2276,"0,0166959578",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,116,Tolerated,"27,92","16,11"
"low bq, low freq, many artifacts, many samples",UPN2_025,2,198267285,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu691Val/c.2072A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6890,119,7044,"0,0168938103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,116,Tolerated,"27,74","15,66"
"low bq, low freq, many artifacts, many samples",UPN2_026,2,198267285,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu691Val/c.2072A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6464,109,6613,"0,0164826856",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,116,Tolerated,"27,55","16,41"
"low bq, low freq, many artifacts, many samples",UPN2_027,2,198267285,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu691Val/c.2072A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),7413,134,7571,"0,017699115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,116,Tolerated,"27,62","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_028,2,198267285,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu691Val/c.2072A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3957,88,4068,"0,0216322517",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,116,Tolerated,"27,6","15,41"
"low bq, many samples",UPN2_029,2,198267285,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu691Val/c.2072A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4862,112,4997,"0,0224134481",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,116,Tolerated,"27,86","18,57"
"low bq, low freq, many artifacts, many samples",UPN2_030,2,198267285,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu691Val/c.2072A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),5042,110,5178,"0,0212437234",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,116,Tolerated,"27,66","18,45"
"low bq, low freq, many artifacts, many samples",UPN2_031,2,198267285,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu691Val/c.2072A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3317,70,3398,"0,0206003531",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,116,Tolerated,"27,79","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_032,2,198267285,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu691Val/c.2072A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1690,27,1726,"0,0156431054",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,116,Tolerated,"27,96","18,89"
"low bq, low freq, many artifacts, many samples",UPN2_033,2,198267285,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu691Val/c.2072A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4257,86,4361,"0,0197202476",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,116,Tolerated,"27,89","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_034,2,198267285,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu691Val/c.2072A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1553,21,1579,"0,0132995567",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,116,Tolerated,"27,37",14
"low bq, low freq, many artifacts, many samples",UPN2_047,2,198267285,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu691Val/c.2072A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),5022,69,5118,"0,0134818288",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,116,Tolerated,"27,98","17,83"
"low bq, low freq, many artifacts, many samples",UPN2_035,2,198267285,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu691Val/c.2072A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3717,75,3813,"0,0196695515",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,116,Tolerated,"27,91","18,29"
"low bq, low freq, many artifacts, many samples",UPN2_036,2,198267285,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu691Val/c.2072A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3671,67,3757,"0,0178333777",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,116,Tolerated,"27,96","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,198267285,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu691Val/c.2072A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2134,37,2187,"0,0169181527",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,116,Tolerated,"27,54","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_037,2,198267285,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu691Val/c.2072A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6615,121,6771,"0,0178703293",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,116,Tolerated,"27,71","16,44"
"low bq, low freq, many artifacts, many samples",UPN2_038,2,198267285,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu691Val/c.2072A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),9424,158,9615,"0,0164326573",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,116,Tolerated,"27,7","15,56"
"low bq, low freq, many artifacts, many samples",UPN2_039,2,198267285,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu691Val/c.2072A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3109,53,3172,"0,0167087011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,116,Tolerated,"27,63","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_009,2,198267285,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu691Val/c.2072A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4493,86,4599,"0,0186997173",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,116,Tolerated,"28,56","15,85"
"low bq, low freq, many artifacts, many samples",UPN2_040,2,198267285,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu691Val/c.2072A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1971,27,2004,"0,0134730539",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,116,Tolerated,"27,66","16,44"
"low bq, low freq, many artifacts",UPN2_013,2,198267285,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu691Val/c.2072A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1128,22,1164,"0,0189003436",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,116,Tolerated,"28,45",16
"low bq, many samples",UPN2_001,2,198267286,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu691*/c.2071G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1374,157,1535,"0,1022801303",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,38","14,39"
"low bq, many samples",UPN2_014,2,198267286,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu691*/c.2071G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3337,329,3671,"0,0896213566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,69","14,19"
"low bq, many samples",UPN2_015,2,198267286,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu691*/c.2071G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4234,391,4630,"0,0844492441",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,7",14
"low bq, many samples",UPN2_016,2,198267286,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu691*/c.2071G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3386,321,3711,"0,0864995958",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,93","14,16"
"low bq, many samples",UPN2_017,2,198267286,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu691*/c.2071G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2153,187,2343,"0,0798122066",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,49",14
"low bq, many samples",UPN2_018,2,198267286,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu691*/c.2071G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3415,333,3755,"0,0886817577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,66","14,14"
"low bq, many samples",UPN2_019,2,198267286,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu691*/c.2071G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3614,357,3979,"0,0897210354",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,72","14,04"
"low bq, many samples",UPN2_020,2,198267286,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu691*/c.2071G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2565,213,2795,"0,0762075134",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,46","14,06"
"low bq, many samples",UPN2_021,2,198267286,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu691*/c.2071G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3643,339,3985,"0,0850690088",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,45","14,1"
"low bq, many samples",UPN2_002,2,198267286,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu691*/c.2071G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2327,226,2555,"0,0884540117",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,43","14,15"
"low bq, many samples",UPN2_003,2,198267286,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu691*/c.2071G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),414,49,465,"0,1053763441",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,62","14,14"
"low bq, many samples",UPN2_022,2,198267286,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu691*/c.2071G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4480,412,4897,"0,0841331427",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,55","14,2"
"low bq, many samples",UPN2_023,2,198267286,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu691*/c.2071G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4392,433,4829,"0,0896665976",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,69",14
"low bq, many samples",UPN2_024,2,198267286,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu691*/c.2071G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2090,169,2259,"0,0748118637",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,55","14,08"
"low bq, many samples",UPN2_025,2,198267286,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu691*/c.2071G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6364,620,6995,"0,0886347391",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,64","14,17"
"low bq, many samples",UPN2_026,2,198267286,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu691*/c.2071G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6007,551,6575,"0,0838022814",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,56","14,09"
"low bq, many samples",UPN2_027,2,198267286,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu691*/c.2071G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6870,635,7513,"0,084520165",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,6","14,07"
"low bq, many samples",UPN2_028,2,198267286,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu691*/c.2071G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3689,343,4039,"0,0849220104",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,76","14,11"
"low bq, many samples",UPN2_044,2,198267286,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu691*/c.2071G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),921,99,1020,"0,0970588235",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,01",14
"low bq, many samples",UPN2_029,2,198267286,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu691*/c.2071G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4553,412,4968,"0,0829307568",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,5","14,03"
"low bq, many samples",UPN2_030,2,198267286,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu691*/c.2071G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4707,419,5132,"0,081644583",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,72","14,03"
"low bq, many samples",UPN2_031,2,198267286,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu691*/c.2071G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3081,278,3372,"0,0824436536",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,54","14,09"
"low bq, many samples",UPN2_005,2,198267286,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu691*/c.2071G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),485,60,546,"0,1098901099",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,48",14
"low bq, many samples",UPN2_032,2,198267286,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu691*/c.2071G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1588,125,1715,"0,0728862974",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,49",14
"low bq, many samples",UPN2_033,2,198267286,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu691*/c.2071G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3929,388,4328,"0,0896487985",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,7","14,09"
"low bq, many samples",UPN2_034,2,198267286,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu691*/c.2071G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1432,138,1570,"0,0878980892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,53","14,35"
many samples,UPN2_047,2,198267286,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu691*/c.2071G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4584,499,5090,"0,0980353635",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,27,"14,3"
"low bq, many samples",UPN2_048,2,198267286,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu691*/c.2071G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),745,94,842,"0,1116389549",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,1","15,07"
"low bq, many samples",UPN2_035,2,198267286,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu691*/c.2071G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3451,326,3785,"0,0861294584",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,7",14
"low bq, many samples",UPN2_036,2,198267286,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu691*/c.2071G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3423,299,3728,"0,0802038627",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,72","14,12"
"low bq, many samples",UPN2_037,2,198267286,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu691*/c.2071G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6135,580,6726,"0,0862325305",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,72","14,13"
"low bq, many samples",UPN2_038,2,198267286,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu691*/c.2071G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),8729,801,9551,"0,0838655638",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,58","14,07"
"low bq, many samples",UPN2_039,2,198267286,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu691*/c.2071G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2885,258,3148,"0,081956798",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,78","14,11"
"low bq, many samples",UPN2_009,2,198267286,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu691*/c.2071G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4097,468,4572,"0,1023622047",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,52","14,43"
"low bq, many samples",UPN2_056,2,198267286,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu691*/c.2071G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),621,67,689,"0,0972423803",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,45","14,33"
"low bq, many samples",UPN2_040,2,198267286,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu691*/c.2071G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1819,159,1983,"0,0801815431",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,67","14,26"
"low bq, many samples",UPN2_013,2,198267286,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu691*/c.2071G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1037,115,1154,"0,0996533795",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,55","14,23"
"low bq, many samples",UPN2_092,2,198267286,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu691*/c.2071G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1738,167,1907,"0,0875721028",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,87","14,43"
"low bq, many samples",UPN2_099,2,198267286,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu691*/c.2071G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1552,202,1755,"0,1150997151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,72","14,36"
low bq,UPN2_108,2,198267286,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu691*/c.2071G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3792,449,4248,"0,1056967985",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,04","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,198267289,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile690Phe/c.2068A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4728,57,4793,"0,011892343",0,0,0,0,1,0,0,0,1,NO,NO,COSM132869,testis,1,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,1,Damaging,"29,42","15,77"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,198267289,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile690Phe/c.2068A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2723,32,2760,"0,0115942029",0,0,0,0,1,0,0,0,1,NO,NO,COSM132869,testis,1,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,1,Damaging,"29,18","16,06"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,198267289,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile690Phe/c.2068A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2872,42,2933,"0,0143198091",0,0,0,0,1,0,0,0,1,NO,NO,COSM132869,testis,1,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,1,Damaging,"28,78","18,9"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,198267289,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile690Phe/c.2068A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3219,34,3260,"0,0104294479",0,0,0,0,1,0,0,0,1,NO,NO,COSM132869,testis,1,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,1,Damaging,"29,24","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,198267289,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile690Phe/c.2068A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4589,51,4654,"0,0109583154",0,0,0,0,1,0,0,0,1,NO,NO,COSM132869,testis,1,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,1,Damaging,"29,39","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,198267289,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile690Phe/c.2068A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4723,53,4788,"0,01106934",0,0,0,0,1,0,0,0,1,NO,NO,COSM132869,testis,1,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,1,Damaging,"29,14","16,08"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,198267289,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile690Phe/c.2068A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3559,38,3612,"0,0105204873",0,0,0,0,1,0,0,0,1,NO,NO,COSM132869,testis,1,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,1,Damaging,"29,27","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,198267289,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile690Phe/c.2068A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4313,48,4378,"0,0109639105",0,0,0,0,1,0,0,0,1,NO,NO,COSM132869,testis,1,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,1,Damaging,"29,38","17,85"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,198267289,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile690Phe/c.2068A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4416,47,4474,"0,0105051408",0,0,0,0,1,0,0,0,1,NO,NO,COSM132869,testis,1,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,1,Damaging,"29,29","15,4"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,198267289,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile690Phe/c.2068A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4638,57,4707,"0,012109624",0,0,0,0,1,0,0,0,1,NO,NO,COSM132869,testis,1,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,1,Damaging,"29,25","16,81"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,198267289,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile690Phe/c.2068A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),7502,78,7597,"0,0102672107",0,0,0,0,1,0,0,0,1,NO,NO,COSM132869,testis,1,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,1,Damaging,"29,29","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,198267289,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile690Phe/c.2068A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6785,86,6893,"0,0124764254",0,0,0,0,1,0,0,0,1,NO,NO,COSM132869,testis,1,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,1,Damaging,"29,08","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,198267289,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile690Phe/c.2068A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4221,49,4281,"0,0114459238",0,0,0,0,1,0,0,0,1,NO,NO,COSM132869,testis,1,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,1,Damaging,"29,21","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,198267289,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile690Phe/c.2068A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6625,76,6720,"0,0113095238",0,0,0,0,1,0,0,0,1,NO,NO,COSM132869,testis,1,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,1,Damaging,"29,3","16,2"
"low bq, low freq, many artifacts, many samples",UPN2_086,2,198267289,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile690Phe/c.2068A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6160,65,6241,"0,0104149976",0,0,0,0,1,0,0,0,1,NO,NO,COSM132869,testis,1,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,1,Damaging,"29,33","15,35"
"low bq, low freq, many artifacts",UPN2_087,2,198267289,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile690Phe/c.2068A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),9158,110,9286,"0,0118457894",0,0,0,0,1,0,0,0,1,NO,NO,COSM132869,testis,1,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,1,Damaging,"29,33","15,96"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,198267290,G,T,missense_variant(MODERATE|MISSENSE|atC/atG|p.Ile689Met/c.2067C>G|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|C),3131,49,3236,"0,0151421508",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,0,Neutral,1,Tolerated,"28,49",14
"low bq, low freq, many artifacts, many samples",UPN2_071,2,198267290,G,T,missense_variant(MODERATE|MISSENSE|atC/atG|p.Ile689Met/c.2067C>G|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|C),4555,84,4736,"0,0177364865",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,0,Neutral,1,Tolerated,"28,94",14
"low bq, low freq, many artifacts, many samples",UPN2_064,2,198267292,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile689Phe/c.2065A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2359,25,2403,"0,0104036621",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,4,Damaging,"29,01",14
"low bq, low freq, many artifacts, many samples",UPN2_001,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1486,22,1512,"0,0145502646",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"29,53",17
"low bq, low freq, many artifacts, many samples",UPN2_014,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3546,51,3611,"0,0141235115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"28,67","19,02"
"low bq, low freq, many artifacts, many samples",UPN2_015,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4472,68,4556,"0,0149253731",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"28,89","17,18"
"low bq, low freq, many artifacts, many samples",UPN2_016,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3587,59,3665,"0,0160982265",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"28,95","17,25"
"low bq, low freq, many artifacts, many samples",UPN2_017,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2256,42,2308,"0,0181975737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"28,62","19,21"
"low bq, low freq, many artifacts, many samples",UPN2_018,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3613,51,3683,"0,013847407",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"28,6","18,76"
"low bq, low freq, many artifacts, many samples",UPN2_019,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3865,42,3917,"0,0107224917",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"28,6","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_020,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2692,45,2754,"0,0163398693",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"28,87","19,09"
"low bq, low freq, many artifacts, many samples",UPN2_021,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3869,48,3927,"0,012223071",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"28,53","16,02"
"low bq, low freq, many artifacts, many samples",UPN2_002,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2472,31,2511,"0,012345679",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"29,52","22,68"
"low bq, low freq, many artifacts, many samples",UPN2_022,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4707,83,4812,"0,0172485453",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"28,78","18,8"
"low bq, low freq, many artifacts, many samples",UPN2_023,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4649,70,4741,"0,0147648175",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"28,69","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_024,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2186,36,2231,"0,0161362618",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"28,86","17,44"
"low bq, low freq, many artifacts, many samples",UPN2_025,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6766,87,6880,"0,0126453488",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"28,71","15,64"
"low bq, low freq, many artifacts, many samples",UPN2_026,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6340,99,6482,"0,0152730639",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"28,65","18,46"
"low bq, low freq, many artifacts, many samples",UPN2_027,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),7268,101,7395,"0,0136578769",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"28,49","17,24"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3938,47,4009,"0,0117236219",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"28,88","22,36"
"low bq, low freq, many artifacts, many samples",UPN2_028,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3904,43,3974,"0,0108203322",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"28,65","18,84"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3205,35,3263,"0,0107263255",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"29,14","17,66"
"low bq, low freq, many artifacts, many samples",UPN2_029,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4786,97,4900,"0,0197959184",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"28,78","20,93"
"low bq, low freq, many artifacts, many samples",UPN2_030,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4963,76,5054,"0,015037594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"28,69","16,13"
"low bq, low freq, many artifacts, many samples",UPN2_031,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3256,57,3330,"0,0171171171",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"28,66","17,16"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),5095,55,5172,"0,0106341841",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"28,99","19,02"
"low bq, low freq, many artifacts, many samples",UPN2_033,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4179,64,4256,"0,015037594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"28,81","18,67"
"low bq, low freq, many artifacts, many samples",UPN2_034,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1519,24,1545,"0,0155339806",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"28,55","17,33"
"low bq, low freq, many artifacts, many samples",UPN2_035,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3655,57,3726,"0,0152979066",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"28,86","17,44"
"low bq, low freq, many artifacts, many samples",UPN2_036,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3590,64,3665,"0,0174624829",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"28,92",16
"low bq, low freq, many artifacts, many samples",UPN2_006,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1860,28,1891,"0,0148069804",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"29,58","19,18"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2127,23,2154,"0,0106778087",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"28,81","18,43"
"low bq, low freq, many artifacts, many samples",UPN2_037,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6517,67,6607,"0,0101407598",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"28,88","15,63"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3951,45,4006,"0,0112331503",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"29,23","18,31"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4309,49,4380,"0,0111872146",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"28,58","19,1"
"low bq, low freq, many artifacts, many samples",UPN2_038,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),9223,129,9402,"0,013720485",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"28,86","16,65"
"low bq, low freq, many artifacts, many samples",UPN2_039,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3039,51,3101,"0,0164463076",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"28,86","19,37"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4376,46,4458,"0,0103185285",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"28,88","19,65"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3613,41,3677,"0,0111503943",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"28,76","19,9"
"low bq, low freq, many artifacts, many samples",UPN2_008,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6367,74,6453,"0,0114675345",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"29,54","17,46"
"low bq, low freq, many artifacts, many samples",UPN2_009,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4417,62,4489,"0,0138115393",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"29,84","17,34"
"low bq, low freq, many artifacts, many samples",UPN2_010,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3373,47,3440,"0,0136627907",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"29,43","16,57"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4335,49,4405,"0,011123723",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"29,03","18,06"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4193,50,4259,"0,011739845",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"29,11","19,2"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4619,55,4693,"0,0117195824",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"29,48","19,69"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4486,52,4552,"0,0114235501",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"29,39","16,04"
"low bq, low freq, many artifacts, many samples",UPN2_040,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1906,29,1942,"0,0149330587",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"28,78","23,41"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2659,40,2707,"0,0147765054",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"29,54","23,62"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2841,31,2878,"0,010771369",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"29,01","16,13"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3143,38,3202,"0,0118675828",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"29,33","17,84"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2336,30,2386,"0,0125733445",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"29,06","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4493,49,4565,"0,0107338445",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"29,61","18,14"
"low bq, low freq, many artifacts, many samples",UPN2_066,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),7405,94,7533,"0,0124784282",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"29,42","16,68"
"low bq, low freq, many artifacts, many samples",UPN2_067,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),7482,81,7594,"0,0106663155",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"29,53","16,49"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4627,62,4706,"0,0131746706",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"29,35","17,98"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6572,67,6655,"0,0100676183",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"29,37","18,67"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3474,45,3541,"0,0127082745",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"29,51","16,84"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3186,43,3243,"0,0132593278",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"29,51","17,28"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3622,54,3688,"0,0146420824",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"29,45","17,43"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4237,45,4299,"0,0104675506",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"29,41","17,62"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6962,103,7092,"0,0145234067",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"29,82","20,71"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3927,55,4001,"0,0137465634",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"29,49","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4528,60,4603,"0,0130349772",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"29,31","17,68"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3388,46,3446,"0,0133488102",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"29,37","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3571,45,3634,"0,012383049",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"29,81",14
"low bq, low freq, many artifacts, many samples",UPN2_081,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4601,49,4664,"0,0105060034",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"29,6","20,06"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),7317,95,7444,"0,0127619559",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"29,6","18,92"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6631,93,6772,"0,0137330183",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"29,16","19,88"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4131,54,4202,"0,0128510233",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"29,38",18
"low bq, low freq, many artifacts, many samples",UPN2_085,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6505,81,6611,"0,0122523068",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"29,53","17,48"
"low bq, low freq, many artifacts, many samples",UPN2_086,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6010,77,6114,"0,0125940465",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"29,46","19,22"
"low bq, low freq, many artifacts, many samples",UPN2_087,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),8960,102,9104,"0,0112038664",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"29,5","15,22"
"low bq, low freq, many artifacts",UPN2_088,2,198267294,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu688Val/c.2063A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),7144,95,7275,"0,0130584192",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,13,Damaging,"29,52","16,33"
"low bq, many samples",UPN2_003,2,198267295,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu688*/c.2062G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),408,29,438,"0,0662100457",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,29,14
"low bq, many samples",UPN2_044,2,198267295,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu688*/c.2062G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),884,105,993,"0,1057401813",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,91","14,42"
"low bq, many samples",UPN2_005,2,198267295,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu688*/c.2062G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),479,39,518,"0,0752895753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,63","14,18"
"low bq, many samples",UPN2_048,2,198267295,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu688*/c.2062G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),726,84,812,"0,1034482759",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,62","14,31"
"low bq, many samples",UPN2_056,2,198267295,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu688*/c.2062G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),600,61,662,"0,0921450151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,74","14,3"
"low bq, many samples",UPN2_013,2,198267295,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu688*/c.2062G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),980,101,1083,"0,0932594645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,16","14,26"
"low bq, many samples",UPN2_067,2,198267295,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu688*/c.2062G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6668,682,7363,"0,0926252886",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,81","15,33"
low bq,UPN2_068,2,198267295,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu688*/c.2062G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4130,413,4552,"0,0907293497",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,41","15,58"
"low bq, many samples",UPN2_003,2,198267298,C,A,missense_variant(MODERATE|MISSENSE|Gtt/Ttt|p.Val687Phe/c.2059G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),395,33,428,"0,0771028037",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"29,59","14,61"
"low bq, many samples",UPN2_005,2,198267298,C,A,missense_variant(MODERATE|MISSENSE|Gtt/Ttt|p.Val687Phe/c.2059G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),476,37,513,"0,0721247563",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"29,08","14,59"
"low bq, many samples",UPN2_056,2,198267298,C,A,missense_variant(MODERATE|MISSENSE|Gtt/Ttt|p.Val687Phe/c.2059G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),609,45,654,"0,0688073394",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"28,15",14
"low bq, many samples",UPN2_001,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1399,41,1440,"0,0284722222",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"27,3","14,76"
"low bq, many samples",UPN2_014,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3319,99,3435,"0,0288209607",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"27,36","14,07"
"low bq, many samples",UPN2_015,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4224,116,4358,"0,0266177145",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"27,39","15,22"
"low bq, many samples",UPN2_016,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3402,87,3494,"0,0248998283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"27,39","15,87"
"low bq, many samples",UPN2_017,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2117,82,2204,"0,0372050817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"27,2","15,22"
"low bq, many samples",UPN2_018,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3404,96,3512,"0,0273348519",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"27,13","15,04"
"low bq, many samples",UPN2_019,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3616,119,3744,"0,031784188",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"27,23","14,6"
"low bq, many samples",UPN2_020,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2565,70,2640,"0,0265151515",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"27,1","16,09"
"low bq, many samples",UPN2_021,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3632,114,3758,"0,0303352847",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"27,08","14,97"
"low bq, many samples",UPN2_002,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2335,57,2396,"0,0237896494",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"27,77","14,46"
"low bq, many samples",UPN2_022,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4461,135,4611,"0,0292778139",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"27,18","15,24"
"low bq, many samples",UPN2_023,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4382,140,4546,"0,0307963044",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"27,16","14,79"
"low bq, many samples",UPN2_024,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2080,66,2148,"0,030726257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"27,34","15,14"
"low bq, many samples",UPN2_025,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6345,220,6573,"0,0334702571",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"27,26","14,62"
"low bq, bad alignment, many samples",UPN2_026,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6011,206,6228,"0,033076429",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"26,91","15,21"
many samples,UPN2_027,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6867,209,7085,"0,0294989414",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,27,"15,07"
"low bq, low freq, many artifacts, many samples",UPN2_089,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2852,48,2902,"0,016540317",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"29,02",14
"low bq, bad alignment, many samples",UPN2_042,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3745,88,3843,"0,022898777",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"25,49","16,19"
"low bq, many samples",UPN2_028,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3687,126,3819,"0,0329929301",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"27,15","15,02"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_043,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3083,62,3151,"0,0196762932",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"25,74",14
"low bq, bad alignment, many samples",UPN2_044,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),956,24,983,"0,024415056",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"25,65",14
"low bq, many samples",UPN2_029,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4527,149,4684,"0,0318104184",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"27,25","15,21"
"low bq, many samples",UPN2_030,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4650,145,4801,"0,0302020412",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"27,19","15,28"
"low bq, many samples",UPN2_031,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3087,91,3182,"0,0285983658",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"27,16","15,77"
"low bq, bad alignment, many samples",UPN2_045,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3220,75,3300,"0,0227272727",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"25,58","16,15"
"low bq, many samples",UPN2_032,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1560,53,1613,"0,0328580285",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"27,47","14,66"
"low bq, bad alignment, many samples",UPN2_046,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4841,127,4980,"0,025502008",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"25,56","14,76"
"low bq, many samples",UPN2_033,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3925,137,4075,"0,0336196319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"27,41","14,92"
"low bq, many samples",UPN2_034,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1426,52,1486,"0,0349932705",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"27,03","16,12"
"low bq, bad alignment, many samples",UPN2_047,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4680,133,4826,"0,0275590551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"25,91","14,5"
"low bq, many samples",UPN2_035,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3450,115,3576,"0,0321588367",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"27,29","16,14"
"low bq, many samples",UPN2_036,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3420,88,3516,"0,0250284414",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"27,23","14,98"
"low bq, many samples",UPN2_006,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1765,43,1812,"0,0237306843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"27,56","14,3"
"low bq, bad alignment, many samples",UPN2_049,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2019,54,2076,"0,0260115607",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"25,61","15,19"
"low bq, bad alignment, many samples",UPN2_050,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2680,73,2761,"0,0264396958",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"25,54","15,1"
"low bq, many samples",UPN2_037,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6150,170,6332,"0,0268477574",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"27,26","15,22"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3767,84,3868,"0,0217166494",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"25,73","15,42"
"low bq, bad alignment, many samples",UPN2_052,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4105,99,4216,"0,0234819734",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"25,3",15
"low bq, many samples",UPN2_038,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),8724,288,9019,"0,0319325868",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"27,24","15,06"
"low bq, many samples",UPN2_039,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2869,95,2966,"0,0320296696",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"27,35","15,25"
"low bq, bad alignment, many samples",UPN2_053,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4166,120,4295,"0,0279394645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"25,49","14,97"
"low bq, bad alignment, many samples",UPN2_054,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3435,90,3535,"0,0254596888",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"25,74","17,37"
"low bq, many samples",UPN2_007,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4505,123,4636,"0,0265314927",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"27,78","14,89"
"low bq, many samples",UPN2_008,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),5955,162,6129,"0,0264317181",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"27,75","15,49"
"low bq, many samples",UPN2_009,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4178,105,4287,"0,0244926522",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"27,87","15,01"
"low bq, many samples",UPN2_010,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3160,93,3263,"0,0285013791",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"27,7","14,14"
"low bq, many samples",UPN2_011,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3948,116,4069,"0,028508233",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"27,52","14,34"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4369,95,4473,"0,0212385424",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"25,78","14,19"
"low bq, low freq, many artifacts, many samples",UPN2_090,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2254,35,2291,"0,0152771715",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"29,5","14,83"
"low bq, bad alignment, many samples",UPN2_057,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4134,113,4250,"0,0265882353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"25,49","15,36"
"low bq, bad alignment, many samples",UPN2_058,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3969,114,4084,"0,02791381",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"25,95","15,54"
"low bq, many samples",UPN2_059,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4341,114,4462,"0,0255490811",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"28,56","14,89"
"low bq, many samples",UPN2_012,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),929,25,954,"0,0262054507",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"27,26","15,76"
"low bq, many samples",UPN2_060,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4209,128,4344,"0,02946593",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"28,39","14,93"
"low bq, many samples",UPN2_040,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1791,48,1848,"0,025974026",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"27,41","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_013,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1049,20,1072,"0,0186567164",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"27,93",14
"low bq, low freq, many artifacts, many samples",UPN2_091,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2324,36,2365,"0,0152219873",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"29,54","15,72"
"low bq, low freq, many artifacts, many samples",UPN2_092,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1760,26,1796,"0,0144766147",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"29,65",14
"low bq, low freq, many artifacts, many samples",UPN2_093,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1375,24,1399,"0,0171551108",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"28,96",14
"low bq, many samples",UPN2_061,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2493,82,2579,"0,0317952695",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"28,47","15,61"
"low bq, many samples",UPN2_062,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2641,75,2729,"0,0274825944",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"28,07","15,32"
"low bq, many samples",UPN2_063,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2929,99,3046,"0,0325016415",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"28,76","14,76"
"low bq, many samples",UPN2_064,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2202,59,2270,"0,0259911894",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"28,17","15,12"
"low bq, many samples",UPN2_065,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4219,126,4350,"0,0289655172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"28,45","14,26"
"low bq, many samples",UPN2_066,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6948,194,7164,"0,0270798437",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"28,56","14,84"
"low bq, many samples",UPN2_067,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),7066,188,7267,"0,0258703729",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"28,54","14,73"
"low bq, many samples",UPN2_068,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4337,139,4485,"0,0309921962",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"28,39","14,47"
"low bq, many samples",UPN2_069,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6117,173,6314,"0,0273994298",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"28,63","15,21"
"low bq, many samples",UPN2_070,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3274,99,3381,"0,0292812777",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"28,61","14,89"
"low bq, many samples",UPN2_071,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4346,142,4501,"0,0315485448",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"28,97","16,01"
"low bq, many samples",UPN2_072,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3004,75,3089,"0,0242797022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"28,62","14,88"
"low bq, many samples",UPN2_073,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3405,109,3524,"0,0309307605",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"28,48","14,37"
"low bq, many samples",UPN2_074,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3978,99,4087,"0,0242231466",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"28,69","14,63"
"low bq, many samples",UPN2_075,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6559,187,6759,"0,0276668146",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"28,87","15,72"
"low bq, many samples",UPN2_076,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3699,117,3823,"0,0306042375",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"28,46","15,06"
"low bq, many samples",UPN2_077,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4036,133,4181,"0,0318105716",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"28,72","14,79"
"low bq, many samples",UPN2_078,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4254,121,4383,"0,0276066621",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"28,42","15,02"
"low bq, many samples",UPN2_079,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3181,105,3301,"0,0318085429",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"28,48","15,18"
"low bq, many samples",UPN2_080,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3322,102,3433,"0,0297116225",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"28,81","16,21"
"low bq, many samples",UPN2_081,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4344,121,4467,"0,0270875308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"28,75","14,87"
"low bq, many samples",UPN2_082,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6886,180,7076,"0,0254381006",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"28,66","14,59"
"low bq, many samples",UPN2_083,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6215,210,6433,"0,0326441785",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"28,28","14,92"
"low bq, many samples",UPN2_084,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3877,125,4009,"0,0311798453",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"28,41","14,92"
"low bq, many samples",UPN2_085,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6100,162,6275,"0,0258167331",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"28,5","14,84"
"low bq, many samples",UPN2_086,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),5655,168,5834,"0,0287967089",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"28,43","14,42"
"low bq, many samples",UPN2_087,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),8415,237,8674,"0,0273230344",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"28,58","15,6"
"low bq, many samples",UPN2_088,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6752,170,6935,"0,0245133381",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"28,65","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_094,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2750,34,2788,"0,012195122",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"29,52",14
"low bq, low freq, many artifacts, many samples",UPN2_095,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2368,43,2414,"0,0178127589",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"29,23","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_096,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2869,39,2913,"0,0133882595",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"29,78","16,15"
"low bq, low freq, many artifacts, many samples",UPN2_097,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2673,45,2728,"0,0164956012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"29,61","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_098,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2271,31,2306,"0,0134431917",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"29,69","17,06"
"low bq, low freq, many artifacts, many samples",UPN2_099,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1589,26,1621,"0,0160394818",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"29,13","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_100,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2347,33,2384,"0,0138422819",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"29,15","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_101,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1985,29,2015,"0,0143920596",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"29,28","16,28"
"low bq, low freq, many artifacts, many samples",UPN2_102,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2334,35,2373,"0,0147492625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"28,78","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_103,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2593,45,2643,"0,0170261067",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"28,96","16,24"
"low bq, low freq, many artifacts, many samples",UPN2_104,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3205,63,3278,"0,019219036",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"29,56",14
"low bq, low freq, many artifacts, many samples",UPN2_105,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2068,40,2117,"0,0188946623",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"29,01","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_106,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3170,55,3229,"0,0170331372",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"29,6",16
"low bq, low freq, many artifacts, many samples",UPN2_107,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),5016,55,5077,"0,0108331692",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"29,71","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_108,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3861,65,3939,"0,0165016502",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"29,68","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_109,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3925,57,3989,"0,0142892956",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"29,5","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_110,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4092,55,4156,"0,0132338787",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"29,58","14,65"
"low bq, low freq, many artifacts",UPN2_111,2,198267299,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu686Phe/c.2058A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2875,58,2939,"0,0197346036",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,1,Damaging,"29,48","14,6"
"low freq, many artifacts",UPN2_052,2,198267301,A,T,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu686Ile/c.2056T>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),4156,49,4214,"0,011627907",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,"0,063",Tolerated,"33,27","27,12"
"low bq, low freq, many artifacts",UPN2_047,2,198267302,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser685Arg/c.2055T>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),4738,59,4822,"0,0122355869",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,95",Deleterious,133,Tolerated,"32,73","24,39"
"low bq, many samples",UPN2_044,2,198267303,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser685Ile/c.2054G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),902,61,965,"0,0632124352",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,61",Deleterious,68,Tolerated,"28,28","14,3"
"low bq, many samples",UPN2_005,2,198267303,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser685Ile/c.2054G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),477,24,501,"0,0479041916",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,61",Deleterious,68,Tolerated,"29,05",14
"low bq, many samples",UPN2_048,2,198267303,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser685Ile/c.2054G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),743,41,785,"0,0522292994",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,61",Deleterious,68,Tolerated,"28,29","14,44"
"low bq, many samples",UPN2_056,2,198267303,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser685Ile/c.2054G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),596,46,642,"0,0716510903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,61",Deleterious,68,Tolerated,"28,77",14
low bq,UPN2_013,2,198267303,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser685Ile/c.2054G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),989,63,1052,"0,0598859316",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,61",Deleterious,68,Tolerated,"29,31",14
"low bq, many samples",UPN2_003,2,198267306,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg684Ile/c.2051G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),388,27,416,"0,0649038462",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,1",Deleterious,5,Damaging,"29,53","14,48"
"low bq, many samples",UPN2_005,2,198267306,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg684Ile/c.2051G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),447,44,491,"0,0896130346",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,1",Deleterious,5,Damaging,"29,5",14
"low bq, many samples",UPN2_048,2,198267306,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg684Ile/c.2051G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),687,68,758,"0,0897097625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,1",Deleterious,5,Damaging,"28,88",14
"low bq, many samples",UPN2_056,2,198267306,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg684Ile/c.2051G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),577,50,628,"0,0796178344",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,1",Deleterious,5,Damaging,"28,48",14
low bq,UPN2_013,2,198267306,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg684Ile/c.2051G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),949,79,1029,"0,0767735666",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,1",Deleterious,5,Damaging,"29,54",14
"low bq, low freq, many artifacts, many samples",UPN2_001,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1345,26,1371,"0,0189642597",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,33",14
"low bq, many samples",UPN2_014,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3190,89,3285,"0,0270928463",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,91","17,16"
"low bq, many samples",UPN2_015,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4053,109,4164,"0,0261767531",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,91","16,44"
"low bq, many samples",UPN2_016,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3242,81,3341,"0,0242442383",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,21","14,89"
"low bq, many samples",UPN2_017,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2046,56,2108,"0,0265654649",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,86","15,04"
"low bq, many samples",UPN2_018,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3266,93,3367,"0,0276210276",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,96","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_019,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3501,72,3583,"0,0200948925",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,91","14,81"
"low bq, many samples",UPN2_020,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2442,74,2520,"0,0293650794",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,94","15,91"
"low bq, many samples",UPN2_021,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3468,103,3577,"0,0287950797",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,7","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_002,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2229,40,2277,"0,0175669741",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,56",14
"low bq, many samples",UPN2_022,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4301,102,4408,"0,0231397459",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,7","14,85"
"low bq, many samples",UPN2_023,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4211,111,4332,"0,0256232687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,91","14,5"
"low bq, many samples",UPN2_024,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2000,46,2050,"0,0224390244",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,91","15,52"
"low bq, many samples",UPN2_025,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6098,178,6287,"0,0283123906",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,95","14,63"
"low bq, many samples",UPN2_026,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),5796,156,5964,"0,0261569416",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,5","15,74"
"low bq, many samples",UPN2_027,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6604,176,6791,"0,0259166544",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,66","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_089,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2767,30,2798,"0,0107219442",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,65","14,97"
"low bq, bad alignment, many samples",UPN2_042,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3545,90,3648,"0,0246710526",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,71","15,4"
"low bq, many samples",UPN2_028,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3558,100,3665,"0,0272851296",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,76","14,82"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_043,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2951,52,3010,"0,0172757475",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,99","14,42"
"low bq, bad alignment, many samples",UPN2_044,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),923,23,946,"0,0243128964",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,61","20,61"
"low bq, many samples",UPN2_029,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4348,133,4487,"0,0296411856",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,77","15,5"
"low bq, many samples",UPN2_030,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4453,115,4578,"0,0251201398",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,97","15,05"
"low bq, many samples",UPN2_031,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2931,94,3027,"0,0310538487",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,01","14,72"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3108,50,3162,"0,0158127767",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,65","14,5"
"low bq, many samples",UPN2_032,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1498,38,1545,"0,0245954693",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,03","18,55"
"low bq, bad alignment, many samples",UPN2_046,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4635,106,4763,"0,0222548814",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,43","16,14"
"low bq, many samples",UPN2_033,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3801,100,3906,"0,0256016385",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,01","15,14"
"low bq, many samples",UPN2_034,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1384,48,1436,"0,0334261838",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,61","15,9"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4521,95,4638,"0,0204829668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,84",15
"low bq, many samples",UPN2_035,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3319,94,3419,"0,0274934191",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,92","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_036,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3276,66,3353,"0,0196838652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,88","15,55"
"low bq, many samples",UPN2_006,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1689,40,1733,"0,0230813618",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,12","16,65"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1946,39,1997,"0,0195292939",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,49","15,59"
"low bq, bad alignment, many samples",UPN2_050,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2573,64,2646,"0,0241874528",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,64","16,22"
"low bq, many samples",UPN2_037,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),5867,167,6061,"0,027553209",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,87","15,86"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3610,69,3687,"0,018714402",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,98","16,42"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3902,88,4004,"0,021978022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,54","15,7"
"low bq, many samples",UPN2_038,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),8392,220,8631,"0,0254895145",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,84","16,18"
"low bq, low freq, many artifacts, many samples",UPN2_039,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2756,61,2824,"0,0216005666",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,94","16,44"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4025,65,4091,"0,0158885358",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,65","14,11"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3302,56,3367,"0,0166320166",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,35","16,27"
"low bq, low freq, many artifacts, many samples",UPN2_007,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4353,79,4439,"0,0177968011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,34","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_008,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),5724,124,5855,"0,0211784799",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,4","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_009,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4017,82,4109,"0,0199561937",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,39","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_010,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3047,52,3101,"0,0167687843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,39","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_011,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3789,77,3880,"0,0198453608",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,36","15,04"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4228,69,4310,"0,0160092807",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,74","15,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3930,81,4018,"0,0201592832",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,8","14,75"
"low bq, bad alignment, many samples",UPN2_058,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3816,87,3914,"0,0222278998",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,99","15,57"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4198,81,4290,"0,0188811189",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,03","15,9"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4086,81,4176,"0,0193965517",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,63","15,96"
"low bq, many samples",UPN2_040,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1710,56,1768,"0,0316742081",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,08","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_013,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1004,22,1028,"0,0214007782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,93",14
"low bq, low freq, many artifacts, many samples",UPN2_091,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2263,24,2293,"0,0104666376",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,05","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2418,49,2472,"0,0198220065",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,78","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2564,47,2623,"0,017918414",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,61","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2849,57,2921,"0,0195138651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,25","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2155,36,2192,"0,0164233577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,61","16,11"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4100,77,4183,"0,0184078413",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,29,"15,4"
"low bq, low freq, many artifacts, many samples",UPN2_066,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6751,115,6879,"0,0167175462",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,05","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_067,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6845,118,6976,"0,0169151376",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,03","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4198,85,4292,"0,019804287",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,97","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),5958,111,6082,"0,0182505755",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,91","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3172,63,3240,"0,0194444444",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,92","14,11"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4227,90,4327,"0,0207996302",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,26","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2911,52,2969,"0,0175143146",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,07","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3296,57,3361,"0,0169592383",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,61","15,37"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3868,56,3928,"0,0142566191",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,07","16,59"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6354,124,6498,"0,0190827947",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,29","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3590,65,3668,"0,0177208288",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,75","15,22"
"low bq, many samples",UPN2_077,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3908,106,4024,"0,0263419483",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,19","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4115,78,4197,"0,0185847034",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,96","15,87"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3099,52,3165,"0,0164296998",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,88","15,75"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3254,62,3322,"0,0186634557",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,98","16,21"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4226,69,4304,"0,0160315985",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,2","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6641,135,6811,"0,019820878",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,12","16,31"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6059,117,6189,"0,018904508",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,77","14,6"
"low bq, many samples",UPN2_084,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3763,98,3866,"0,0253491981",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,62","15,86"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),5905,100,6017,"0,0166195779",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,97",15
"low bq, low freq, many artifacts, many samples",UPN2_086,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),5470,110,5600,"0,0196428571",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,95","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_087,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),8112,160,8296,"0,0192864031",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,03","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_088,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6537,111,6661,"0,0166641645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,07","15,17"
"low bq, low freq, many artifacts, many samples",UPN2_106,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3084,42,3128,"0,01342711",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,23","15,74"
"low bq, low freq, many artifacts",UPN2_111,2,198267307,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg684*/c.2050A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2818,29,2851,"0,0101718695",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,91",14
"low bq, many samples",UPN2_089,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2257,57,2337,"0,0243902439",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"34,61","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_090,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1779,36,1844,"0,0195227766",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"34,63","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3322,53,3424,"0,015478972",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"33,98","15,66"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3226,64,3352,"0,0190930788",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"33,89","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_091,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1876,35,1931,"0,0181253237",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"34,64","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_092,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1393,23,1431,"0,0160726765",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"34,56","15,91"
"low bq, low freq, many artifacts, many samples",UPN2_093,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1078,20,1117,"0,017905103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"34,83",14
"low bq, low freq, many artifacts, many samples",UPN2_061,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1919,38,1986,"0,0191339376",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"33,66","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2015,33,2088,"0,0158045977",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"33,63","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2262,46,2352,"0,0195578231",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"33,92","15,52"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1683,25,1731,"0,0144425188",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"33,63","15,6"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3202,50,3306,"0,0151240169",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"33,95","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_066,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),5296,80,5464,"0,0146412884",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"34,03","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_067,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),5338,82,5535,"0,0148148148",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"33,97","15,77"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3305,62,3431,"0,0180705334",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"33,79","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4723,86,4881,"0,0176193403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"33,82","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2492,37,2578,"0,014352211",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"33,96","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3354,48,3457,"0,0138848713",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"33,91","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2290,32,2364,"0,013536379",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"34,08","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2568,31,2641,"0,011737978",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"33,86","15,42"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3065,60,3181,"0,0188619931",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"33,97",14
"low bq, low freq, many artifacts, many samples",UPN2_075,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),5037,87,5206,"0,0167114867",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"34,11","16,08"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2777,51,2897,"0,0176044184",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"34,07","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3080,43,3177,"0,0135347812",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"34,04",14
"low bq, low freq, many artifacts, many samples",UPN2_078,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3234,49,3331,"0,0147102972",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"34,07","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2398,34,2497,"0,0136163396",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"34,08","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2578,32,2652,"0,012066365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"34,01","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3345,55,3450,"0,015942029",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"34,11","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),5294,80,5461,"0,0146493316",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"33,87","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_083,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4726,75,4882,"0,0153625563",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"33,82",15
"low bq, low freq, many artifacts, many samples",UPN2_084,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2959,49,3050,"0,0160655738",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"33,74","15,53"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4632,88,4801,"0,0183295147",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"34,08","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_086,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4334,77,4488,"0,0171568627",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"33,99","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_087,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),6387,97,6615,"0,0146636432",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,34,"15,47"
"low bq, low freq, many artifacts, many samples",UPN2_088,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),5157,94,5364,"0,0175242356",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"33,88","15,73"
"low bq, low freq, many artifacts, many samples",UPN2_094,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2208,44,2283,"0,0192728866",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"34,66",14
"low bq, low freq, many artifacts, many samples",UPN2_095,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1887,27,1949,"0,0138532581",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"34,42",14
"low bq, low freq, many artifacts, many samples",UPN2_096,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2283,32,2342,"0,0136635354",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"34,76","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_097,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2158,40,2222,"0,0180018002",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"34,7","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_098,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1851,33,1904,"0,0173319328",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"34,38","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_100,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1870,34,1927,"0,0176440062",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"34,34","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_101,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1625,26,1669,"0,0155781905",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"34,05","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_102,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1852,29,1903,"0,0152390962",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"34,39",14
"low bq, many samples",UPN2_103,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2096,48,2166,"0,0221606648",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"34,23","14,15"
"low bq, low freq, many artifacts, many samples",UPN2_104,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2609,46,2686,"0,0171258377",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"34,22","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_105,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1692,32,1743,"0,0183591509",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"34,3",14
"low bq, low freq, many artifacts, many samples",UPN2_106,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2528,43,2607,"0,0164940545",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"34,83","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_107,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4078,76,4204,"0,0180780209",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"34,7","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_108,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3111,54,3202,"0,0168644597",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"34,71","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_109,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3131,54,3227,"0,0167338085",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"34,79","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_110,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3307,56,3407,"0,0164367479",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"34,65","15,46"
"low bq, low freq, many artifacts",UPN2_111,2,198267310,G,A,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu683Phe/c.2047C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2321,41,2386,"0,0171835708",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,91",Deleterious,0,Damaging,"34,69","15,51"
"low bq, many samples",UPN2_014,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),2094,63,2176,"0,0289522059",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"34,96",14
"low bq, many samples",UPN2_015,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),2667,81,2764,"0,0293053546",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"34,89",14
"low bq, many samples",UPN2_016,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),2154,70,2240,"0,03125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"34,99",14
"low bq, many samples",UPN2_017,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),1353,36,1398,"0,025751073",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"34,55",14
"low bq, many samples",UPN2_018,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),2148,54,2212,"0,0244122966",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"34,92","14,54"
"low bq, many samples",UPN2_019,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),2282,72,2369,"0,0303925707",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"34,88",14
"low bq, many samples",UPN2_020,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),1608,56,1680,"0,0333333333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"34,85",14
"low bq, many samples",UPN2_021,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),2269,74,2355,"0,0314225053",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"34,85",14
"low bq, many samples",UPN2_002,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),1554,36,1605,"0,0224299065",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"34,26",14
"low bq, many samples",UPN2_022,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),2818,81,2923,"0,0277112556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"34,85",14
"low bq, many samples",UPN2_023,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),2801,94,2920,"0,0321917808",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"34,73",14
"low bq, low freq, many artifacts, many samples",UPN2_024,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),1309,27,1345,"0,0200743494",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"34,77",14
"low bq, many samples",UPN2_025,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),4010,133,4170,"0,0318944844",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"34,8","14,4"
"low bq, many samples",UPN2_026,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),3753,111,3890,"0,0285347044",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"34,91","14,46"
"low bq, many samples",UPN2_027,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),4330,120,4483,"0,0267677894",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"34,77","14,06"
"low bq, many samples",UPN2_042,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),2342,54,2409,"0,0224159402",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"34,31",14
"low bq, many samples",UPN2_028,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),2314,68,2403,"0,0282979609",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"34,82",14
"low bq, many samples",UPN2_043,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),1904,63,1981,"0,0318021201",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"33,98","15,6"
"low bq, many samples",UPN2_029,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),2829,86,2938,"0,0292716133",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"34,93",14
"low bq, many samples",UPN2_030,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),2987,79,3089,"0,0255746196",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"34,69","14,28"
"low bq, many samples",UPN2_031,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),1934,61,2009,"0,0303633649",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"34,73","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),2027,39,2074,"0,018804243",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"34,05",14
"low bq, many samples",UPN2_032,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),997,25,1034,"0,0241779497",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"34,72",14
"low bq, low freq, many artifacts, many samples",UPN2_046,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),3038,67,3125,"0,02144",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"34,13","14,19"
"low bq, many samples",UPN2_033,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),2491,66,2573,"0,0256509911",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"34,73",14
"low bq, many samples",UPN2_034,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),892,29,926,"0,0313174946",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"34,92",14
"low bq, low freq, many artifacts, many samples",UPN2_047,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),2985,62,3072,"0,0201822917",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"33,86","14,35"
"low bq, many samples",UPN2_035,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),2169,68,2256,"0,030141844",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"34,84",14
"low bq, many samples",UPN2_036,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),2161,60,2234,"0,0268576544",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"34,75",14
"low bq, many samples",UPN2_049,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),1238,31,1278,"0,024256651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"34,02","14,42"
"low bq, many samples",UPN2_050,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),1666,39,1717,"0,0227140361",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"34,33",14
"low bq, many samples",UPN2_037,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),3843,104,3965,"0,0262295082",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"34,88","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),2358,43,2413,"0,0178201409",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"33,88","14,51"
"low bq, many samples",UPN2_052,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),2546,67,2638,"0,0253980288",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"34,01","14,19"
"low bq, many samples",UPN2_038,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),5443,175,5659,"0,0309241916",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"34,79","14,13"
"low bq, many samples",UPN2_039,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),1818,62,1892,"0,032769556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"34,81","14,35"
"low bq, many samples",UPN2_053,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),2605,64,2687,"0,0238183848",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"33,85","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),2155,38,2209,"0,017202354",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"33,82",14
"low bq, low freq, many artifacts, many samples",UPN2_007,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),2993,50,3063,"0,0163238655",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"34,52",14
"low bq, low freq, many artifacts, many samples",UPN2_008,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),3995,53,4068,"0,0130285152",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"34,25",14
"low bq, low freq, many artifacts, many samples",UPN2_009,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),2778,32,2823,"0,0113354587",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"34,6","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_010,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),2126,29,2171,"0,0133578996",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"34,39",14
"low bq, low freq, many artifacts, many samples",UPN2_011,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),2611,39,2674,"0,0145848915",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"34,57","14,56"
"low bq, many samples",UPN2_055,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),2710,72,2805,"0,0256684492",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"33,97","14,1"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),2563,58,2648,"0,0219033233",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"34,12",14
"low bq, many samples",UPN2_058,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),2528,65,2620,"0,0248091603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"34,15",14
low bq,UPN2_040,2,198267310,G,T,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu683Ile/c.2047C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),1137,30,1172,"0,0255972696",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,0,Damaging,"34,9",14
"low freq, many artifacts",UPN2_036,2,198267312,T,A,missense_variant(MODERATE|MISSENSE|cAt/cTt|p.His682Leu/c.2045A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2052,21,2082,"0,0100864553",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,65",Deleterious,1,Damaging,"35,22","34,1"
"inspected, many artifacts",UPN2_044,2,198267324,G,C,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala678Gly/c.2033C>G|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|C),554,20,576,"0,0347222222",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,24",Deleterious,"0,287",Tolerated,"34,53","31,75"
many samples,UPN2_001,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),6162,575,6763,"0,0850214402",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,17","31,36"
"inspected, strandbias, many samples",UPN2_014,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),10465,684,11178,"0,0611916264",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,"0,001",Damaging,"32,48","31,43"
many samples,UPN2_015,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),14579,716,15342,"0,0466692739",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,43","31,36"
"strandbias, many samples",UPN2_016,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),8138,397,8562,"0,0463676711",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,"0,001",Damaging,"32,67","31,49"
many samples,UPN2_017,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),5432,354,5807,"0,0609609092",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,6","31,2"
many samples,UPN2_018,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),8117,430,8577,"0,0501340795",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,72","31,36"
many samples,UPN2_019,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),9141,568,9737,"0,0583341892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,67","31,53"
many samples,UPN2_020,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),7199,483,7700,"0,0627272727",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,53","31,36"
many samples,UPN2_021,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),8843,543,9413,"0,0576861787",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,6","31,38"
many samples,UPN2_002,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),7799,700,8518,"0,0821789152",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,38","31,53"
many samples,UPN2_003,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),1417,122,1542,"0,0791180285",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,27","31,02"
many samples,UPN2_022,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),11383,606,12027,"0,0503866301",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,61","31,5"
many samples,UPN2_023,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),12327,668,13027,"0,0512781147",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,53","31,21"
many samples,UPN2_024,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),5922,266,6206,"0,0428617467",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,54","31,62"
many samples,UPN2_025,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),14165,680,14896,"0,0456498389",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,74","31,19"
many samples,UPN2_026,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),14340,815,15194,"0,0536395946",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,68","31,41"
many samples,UPN2_004,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),1158,110,1273,"0,086410055",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"31,96","30,98"
many samples,UPN2_027,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),15584,1033,16660,"0,0620048019",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,66","31,52"
"low freq, many artifacts, many samples",UPN2_042,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),3551,37,3615,"0,0102351314",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"33,06","31,22"
"strandbias, many samples",UPN2_028,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),10711,680,11432,"0,0594821554",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,"0,001",Damaging,"32,53","31,45"
many samples,UPN2_043,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),7118,179,7343,"0,0243769576",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,28","31,47"
many samples,UPN2_044,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),2813,98,2916,"0,0336076818",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,26","31,3"
"strandbias, many samples",UPN2_029,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),13230,882,14155,"0,0623101378",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,"0,001",Damaging,"32,51","31,41"
"strandbias, many samples",UPN2_030,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),11869,695,12600,"0,0551587302",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,"0,001",Damaging,"32,62","31,77"
many samples,UPN2_031,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),7206,362,7593,"0,0476754906",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,63","31,23"
"strandbias, many samples",UPN2_005,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),1723,189,1917,"0,0985915493",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,"0,001",Damaging,"32,29","31,4"
"low freq, many artifacts, many samples",UPN2_045,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),10245,173,10452,"0,0165518561",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,15","31,39"
many samples,UPN2_032,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),4936,293,5258,"0,0557246101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,5","31,28"
many samples,UPN2_046,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),11457,437,11927,"0,0366395573",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,25","31,49"
many samples,UPN2_033,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),9996,525,10554,"0,0497441728",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,66","31,61"
many samples,UPN2_034,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),3988,226,4225,"0,0534911243",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,59","31,24"
many samples,UPN2_035,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),10462,767,11265,"0,0680869951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,49","31,6"
"strandbias, many samples",UPN2_036,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),10871,825,11765,"0,0701232469",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,"0,001",Damaging,"32,41","31,43"
many samples,UPN2_006,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),2856,235,3103,"0,0757331615",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,94","31,68"
"low freq, many artifacts, many samples",UPN2_049,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),2355,44,2412,"0,0182421227",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,84","30,77"
many samples,UPN2_037,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),15837,835,16714,"0,0499581189",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,62","31,41"
"low freq, many artifacts, many samples",UPN2_051,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),11443,210,11699,"0,0179502522",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,08","30,99"
many samples,UPN2_038,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),20783,1220,22070,"0,0552786588",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,64","31,5"
many samples,UPN2_039,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),7839,486,8353,"0,0581826889",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,49","31,25"
"strandbias, many samples",UPN2_053,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),13420,408,13888,"0,0293778802",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,"0,001",Damaging,"32,06","31,44"
"low freq, many artifacts, many samples",UPN2_054,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),9939,160,10135,"0,0157868772",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,14","31,31"
many samples,UPN2_007,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),17522,1445,19036,"0,0759088044",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,26","31,43"
many samples,UPN2_008,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),22712,1747,24545,"0,0711753921",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,29","31,37"
"strandbias, many samples",UPN2_009,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),18637,1293,19996,"0,0646629326",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,"0,001",Damaging,"32,24","31,4"
many samples,UPN2_010,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),13996,1100,15133,"0,0726888257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,27","31,59"
many samples,UPN2_011,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),15962,1400,17401,"0,0804551463",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,23","31,43"
"strandbias, many samples",UPN2_055,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),9857,223,10114,"0,0220486454",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,"0,001",Damaging,"32,25","31,19"
"strandbias, many samples",UPN2_057,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),13759,444,14276,"0,0311011488",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,"0,001",Damaging,"32,08","30,93"
many samples,UPN2_058,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),16531,777,17353,"0,0447761194",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,04","31,27"
many samples,UPN2_012,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),5967,479,6460,"0,0741486068",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,11","31,25"
many samples,UPN2_060,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),7987,495,8524,"0,058071328",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,76","31,01"
many samples,UPN2_040,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),6756,481,7254,"0,0663082437",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,36","31,44"
many samples,UPN2_013,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),4400,350,4769,"0,0733906479",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,23","31,07"
many samples,UPN2_061,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),9739,826,10609,"0,0778584221",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,12","31,12"
"strandbias, many samples",UPN2_062,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),8937,775,9734,"0,0796178344",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,"0,001",Damaging,"32,24","31,34"
many samples,UPN2_063,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),9287,826,10137,"0,0814836737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,38","31,2"
"low freq, many artifacts, many samples",UPN2_064,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),2018,41,2063,"0,0198739699",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"33,85","30,56"
"low freq, many artifacts, many samples",UPN2_065,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),4173,83,4260,"0,0194835681",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"33,75","30,7"
"strandbias, many samples",UPN2_066,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),13366,751,14153,"0,0530629549",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,"0,001",Damaging,"32,73","31,12"
"strandbias, many samples",UPN2_067,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),15674,926,16657,"0,0555922435",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,"0,001",Damaging,"32,63","31,37"
"strandbias, many samples",UPN2_068,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),11438,702,12191,"0,0575834632",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,"0,001",Damaging,"32,46","31,41"
many samples,UPN2_069,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),14679,923,15646,"0,0589927138",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,52","31,13"
many samples,UPN2_070,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),8689,611,9331,"0,0654806559",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,49","31,13"
many samples,UPN2_071,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),7478,451,7960,"0,0566582915",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,88","31,04"
many samples,UPN2_072,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),4980,333,5330,"0,0624765478",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,96","30,93"
many samples,UPN2_073,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),3590,115,3721,"0,0309056705",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"33,7","31,34"
many samples,UPN2_074,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),6962,392,7373,"0,0531669605",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,9","31,19"
many samples,UPN2_075,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),12314,727,13084,"0,0555640477",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,81","31,09"
"strandbias, many samples",UPN2_076,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),9716,744,10500,"0,0708571429",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,"0,001",Damaging,"32,46","31,06"
many samples,UPN2_077,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),10683,731,11459,"0,0637926521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,45","31,25"
"strandbias, many samples",UPN2_078,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),9624,683,10345,"0,066022233",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,"0,001",Damaging,"32,58","31,2"
"strandbias, many samples",UPN2_079,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),6118,389,6522,"0,0596442809",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,"0,001",Damaging,"32,77","31,24"
many samples,UPN2_080,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),6246,408,6661,"0,0612520643",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,84","31,21"
"low freq, many artifacts, many samples",UPN2_081,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),3731,46,3791,"0,0121340016",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"34,04","31,61"
many samples,UPN2_082,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),11633,494,12165,"0,0406083025",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,93","31,24"
"strandbias, many samples",UPN2_083,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),13784,990,14819,"0,0668061273",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,"0,001",Damaging,"32,64","31,2"
many samples,UPN2_084,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),12555,900,13485,"0,0667408231",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,27","31,25"
"strandbias, many samples",UPN2_085,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),10546,549,11136,"0,049299569",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,"0,001",Damaging,"32,88","31,2"
many samples,UPN2_086,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),9047,419,9486,"0,0441703563",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,91","31,24"
"strandbias, many samples",UPN2_087,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),13849,691,14585,"0,0473774426",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,"0,001",Damaging,"33,01","31,3"
"inspected, strandbias",UPN2_088,2,198267330,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly676Ala/c.2027G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),12060,673,12795,"0,0525986714",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"32,81","31,12"
"low freq, many artifacts",UPN2_064,2,198267331,C,T,missense_variant(MODERATE|MISSENSE|Ggc/Agc|p.Gly676Ser/c.2026G>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),2096,22,2127,"0,0103432064",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,1,Damaging,"33,4","34,59"
"low freq, many artifacts",UPN2_044,2,198267334,T,C,missense_variant(MODERATE|MISSENSE|Atg/Gtg|p.Met675Val/c.2023A>G|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|C),2946,39,2992,"0,0130347594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,13",Deleterious,67,Tolerated,"31,88","31,18"
"low freq, many artifacts",UPN2_044,2,198267345,A,T,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile671Lys/c.2012T>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),2933,53,2993,"0,0177079853",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,94",Deleterious,0,Damaging,"34,92","34,6"
"low freq, many artifacts",UPN2_019,2,198267359,C,G,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys666Asn/c.1998G>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),9789,116,9938,"0,0116723687",0,0,0,0,1,0,0,0,1,"0,0116",NO,COSM132937,haematopoietic_and_lymphoid_tissue. liver,"20,1",NO,rs377023736,NO,NA,NO,NO,"-4,88",Deleterious,0,Damaging,"35,6","34,95"
"low bq, low freq, many artifacts",UPN2_054,2,198267370,T,A,missense_variant(MODERATE|MISSENSE|Act/Tct|p.Thr663Ser/c.1987A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),10216,106,10361,"0,0102306727",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,89",Deleterious,"0,01",Damaging,"34,63","24,36"
"low freq, many artifacts",UPN2_044,2,198267381,T,C,missense_variant(MODERATE|MISSENSE|cAa/cGa|p.Gln659Arg/c.1976A>G|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|C),2924,54,2995,"0,0180300501",0,0,0,0,1,1,0,1,3,NO,NO,COSM1291401,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-3,61",Deleterious,"0,109",Tolerated,"33,7","34,59"
"low freq, many artifacts",UPN2_006,2,198267390,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys656Met/c.1967A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2109,38,2154,"0,017641597",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,82",Deleterious,0,Damaging,"34,97","31,45"
"low freq, many artifacts",UPN2_042,2,198267397,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser654Gly/c.1960A>G|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|C),1499,20,1530,"0,0130718954",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,88",Deleterious,0,Damaging,"34,49","35,15"
"low freq, many artifacts",UPN2_006,2,198267397,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser654Gly/c.1960A>G|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|C),2110,30,2154,"0,0139275766",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,88",Deleterious,0,Damaging,"34,59","35,47"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,198267398,T,A,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys653Asn/c.1959A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),8663,90,8790,"0,0102389078",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,4",Neutral,143,Tolerated,"33,8","18,8"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,198267398,T,A,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys653Asn/c.1959A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),8963,92,9107,"0,0101021192",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,4",Neutral,143,Tolerated,"33,96","18,93"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,198267399,T,A,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys653Ile/c.1958A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1332,20,1364,"0,0146627566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,09",Deleterious,4,Damaging,"34,23","21,5"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,198267410,T,A,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys649Asn/c.1947A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),8618,93,8787,"0,010583817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,75",Deleterious,93,Tolerated,"34,03","16,94"
"low bq, low freq, many artifacts",UPN2_057,2,198267410,T,A,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys649Asn/c.1947A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),11934,129,12188,"0,0105841812",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,75",Deleterious,93,Tolerated,"33,93","20,03"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,198267411,T,A,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys649Ile/c.1946A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),5562,86,5667,"0,0151755779",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,1,Damaging,"33,37","16,47"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,198267411,T,A,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys649Ile/c.1946A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2370,33,2416,"0,0136589404",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,1,Damaging,"33,1","17,27"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,198267411,T,A,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys649Ile/c.1946A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),8642,98,8785,"0,0111553785",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,1,Damaging,"33,27","16,27"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,198267411,T,A,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys649Ile/c.1946A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),9171,99,9312,"0,0106314433",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,1,Damaging,"33,39","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,198267411,T,A,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys649Ile/c.1946A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),9539,107,9706,"0,0110241088",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,1,Damaging,"33,31","16,65"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,198267411,T,A,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys649Ile/c.1946A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),8942,118,9101,"0,0129656082",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,1,Damaging,"33,34","17,31"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,198267411,T,A,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys649Ile/c.1946A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),11455,143,11664,"0,0122599451",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,1,Damaging,"33,3","16,76"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,198267411,T,A,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys649Ile/c.1946A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),8109,110,8271,"0,0132994801",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,1,Damaging,"33,45","19,77"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,198267411,T,A,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys649Ile/c.1946A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),7589,110,7740,"0,0142118863",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,1,Damaging,"33,31","17,66"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,198267411,T,A,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys649Ile/c.1946A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),11970,160,12188,"0,0131276666",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,1,Damaging,"33,39","17,17"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,198267411,T,A,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys649Ile/c.1946A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),15194,198,15467,"0,0128014482",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,1,Damaging,"33,32","16,15"
"low bq, low freq, many artifacts",UPN2_074,2,198267411,T,A,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys649Ile/c.1946A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),4433,46,4496,"0,0102313167",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,1,Damaging,"33,5","16,04"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,198267412,T,A,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys649*/c.1945A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),5576,57,5667,"0,0100582319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,48","17,05"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,198267412,T,A,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys649*/c.1945A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2378,29,2416,"0,0120033113",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,75","16,07"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,198267412,T,A,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys649*/c.1945A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),8625,118,8785,"0,0134319863",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,6","16,77"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,198267412,T,A,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys649*/c.1945A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1336,24,1366,"0,0175695461",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,47","22,62"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,198267412,T,A,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys649*/c.1945A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),8078,87,8196,"0,0106149341",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,59","17,11"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,198267412,T,A,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys649*/c.1945A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),9567,106,9706,"0,0109210797",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,73","18,23"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,198267412,T,A,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys649*/c.1945A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),8154,84,8273,"0,0101535114",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,81","17,45"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,198267412,T,A,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys649*/c.1945A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),7622,80,7740,"0,0103359173",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,81","18,49"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,198267412,T,A,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys649*/c.1945A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),12004,130,12188,"0,0106662291",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,72","18,6"
"low bq, low freq, many artifacts",UPN2_058,2,198267412,T,A,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys649*/c.1945A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),15248,170,15467,"0,0109911424",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,6","18,52"
"low bq, low freq, many artifacts",UPN2_044,2,198267425,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu644Phe/c.1932A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2380,26,2414,"0,0107705054",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,88",Deleterious,94,Tolerated,"33,42","17,77"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,198267436,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile641Phe/c.1921A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),5593,61,5672,"0,0107545839",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"31,77","17,66"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,198267436,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile641Phe/c.1921A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2377,33,2415,"0,0136645963",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"32,03","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,198267436,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile641Phe/c.1921A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),8669,105,8800,"0,0119318182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"31,88","18,15"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,198267436,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile641Phe/c.1921A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),9176,111,9321,"0,0119085935",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,32,"18,48"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,198267436,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile641Phe/c.1921A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),8075,100,8194,"0,0122040517",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"32,14","17,42"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,198267436,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile641Phe/c.1921A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),9550,117,9709,"0,0120506746",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"32,14","17,1"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,198267436,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile641Phe/c.1921A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),11498,132,11677,"0,0113042734",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"32,16","16,93"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,198267436,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile641Phe/c.1921A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),7617,91,7736,"0,0117631851",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"32,18","16,09"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,198267436,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile641Phe/c.1921A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),12021,138,12194,"0,0113170412",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"31,94","17,86"
"low bq, low freq, many artifacts",UPN2_058,2,198267436,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile641Phe/c.1921A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),15277,162,15486,"0,0104610616",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"31,9","17,19"
"low bq, low freq, many artifacts",UPN2_073,2,198267439,C,A,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly640Cys/c.1918G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),2532,28,2580,"0,0108527132",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,73",Deleterious,0,Damaging,"28,06","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,198267444,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala638Asp/c.1913C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),10906,134,11078,"0,0120960462",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,82",Deleterious,0,Damaging,"27,92","16,46"
"low bq, low freq, many artifacts, many samples",UPN2_061,2,198267444,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala638Asp/c.1913C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),17940,185,18182,"0,0101748983",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,82",Deleterious,0,Damaging,"28,05","16,15"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,198267444,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala638Asp/c.1913C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),15806,166,16037,"0,0103510632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,82",Deleterious,0,Damaging,"28,08","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,198267444,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala638Asp/c.1913C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),16127,166,16337,"0,0101609843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,82",Deleterious,0,Damaging,"28,05","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_066,2,198267444,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala638Asp/c.1913C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),18289,215,18574,"0,0115753203",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,82",Deleterious,0,Damaging,"28,03","15,93"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,198267444,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala638Asp/c.1913C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),8878,94,8994,"0,0104514121",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,82",Deleterious,0,Damaging,"27,98","16,53"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,198267444,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala638Asp/c.1913C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),16584,202,16849,"0,0119888421",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,82",Deleterious,0,Damaging,"27,88","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,198267444,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala638Asp/c.1913C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),17088,181,17301,"0,010461823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,82",Deleterious,0,Damaging,"28,12","15,87"
"low bq, low freq, many artifacts, many samples",UPN2_079,2,198267444,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala638Asp/c.1913C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),8491,107,8627,"0,0124029211",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,82",Deleterious,0,Damaging,"27,9","16,03"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,198267444,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala638Asp/c.1913C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),14229,175,14454,"0,0121073751",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,82",Deleterious,0,Damaging,"27,94","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,198267444,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala638Asp/c.1913C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),21750,253,22069,"0,0114640446",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,82",Deleterious,0,Damaging,"28,03","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_085,2,198267444,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala638Asp/c.1913C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),13453,166,13659,"0,0121531591",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,82",Deleterious,0,Damaging,"28,03","15,42"
"low bq, low freq, many artifacts",UPN2_086,2,198267444,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala638Asp/c.1913C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),10641,121,10804,"0,0111995557",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,82",Deleterious,0,Damaging,"28,14","16,04"
"low freq, many artifacts",UPN2_047,2,198267444,GC,G,frameshift_variant(HIGH||gcc/|p.Ala638fs/c.1912delG|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|G),2092,27,2133,"0,0126582278",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,74",NA
"low freq, many artifacts",UPN2_042,2,198267450,G,A,missense_variant(MODERATE|MISSENSE|gCc/gTc|p.Ala636Val/c.1907C>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3022,33,3080,"0,0107142857",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,88",Deleterious,"0,001",Damaging,"29,8","29,73"
"low bq, low freq, many artifacts",UPN2_063,2,198267450,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala636Asp/c.1907C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),16132,165,16364,"0,0100831093",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,83",Deleterious,0,Damaging,"28,72","15,55"
"low bq, low freq, many artifacts",UPN2_042,2,198267451,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala636Ser/c.1906G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),3026,37,3079,"0,0120168886",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,91",Deleterious,24,Damaging,"32,66","20,78"
"low freq, many artifacts",UPN2_044,2,198267461,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe632Leu/c.1896T>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),4764,61,4850,"0,0125773196",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,83",Deleterious,"0,117",Tolerated,"32,29","28,61"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,198267475,T,A,missense_variant(MODERATE|MISSENSE|Aca/Tca|p.Thr628Ser/c.1882A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),17914,203,18175,"0,0111691884",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,88",Deleterious,"0,02",Damaging,"32,18","17,42"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,198267475,T,A,missense_variant(MODERATE|MISSENSE|Aca/Tca|p.Thr628Ser/c.1882A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),23965,273,24319,"0,0112257905",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,88",Deleterious,"0,02",Damaging,"32,09","17,27"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,198267475,T,A,missense_variant(MODERATE|MISSENSE|Aca/Tca|p.Thr628Ser/c.1882A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),8299,91,8422,"0,0108050344",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,88",Deleterious,"0,02",Damaging,"32,02","19,11"
"inspected, many artifacts",UPN2_081,2,198267475,T,A,missense_variant(MODERATE|MISSENSE|Aca/Tca|p.Thr628Ser/c.1882A>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|A),1171,34,1212,"0,0280528053",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,88",Deleterious,"0,02",Damaging,"32,02","26,79"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,198267477,G,C,missense_variant(MODERATE|MISSENSE|aCa/aGa|p.Thr627Arg/c.1880C>G|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|C),2399,26,2433,"0,0106863954",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,69",Deleterious,1,Damaging,"28,81",14
"low bq, low freq, many artifacts, many samples",UPN2_060,2,198267484,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg625Ser/c.1873C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),5517,64,5599,"0,0114306126",0,0,0,0,1,0,0,0,1,NO,NO,COSM1658998,salivary_gland,1,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,0,Damaging,"28,96","16,55"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,198267484,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg625Ser/c.1873C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),7031,72,7118,"0,0101152009",0,0,0,0,1,0,0,0,1,NO,NO,COSM1658998,salivary_gland,1,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,0,Damaging,"29,21","15,65"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,198267484,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg625Ser/c.1873C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),4487,49,4543,"0,0107858243",0,0,0,0,1,0,0,0,1,NO,NO,COSM1658998,salivary_gland,1,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,0,Damaging,"29,05","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,198267484,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg625Ser/c.1873C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),7316,75,7403,"0,010131028",0,0,0,0,1,0,0,0,1,NO,NO,COSM1658998,salivary_gland,1,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,0,Damaging,"29,26","16,83"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,198267484,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg625Ser/c.1873C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),7222,77,7314,"0,010527755",0,0,0,0,1,0,0,0,1,NO,NO,COSM1658998,salivary_gland,1,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,0,Damaging,"29,03","15,48"
"low bq, low freq, many artifacts",UPN2_085,2,198267484,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg625Ser/c.1873C>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),6823,73,6913,"0,0105598148",0,0,0,0,1,0,0,0,1,NO,NO,COSM1658998,salivary_gland,1,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,0,Damaging,"29,09","16,15"
"low freq, many artifacts",UPN2_044,2,198267486,A,T,missense_variant(MODERATE|MISSENSE|gTc/gAc|p.Val624Asp/c.1871T>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|14|T),2389,40,2446,"0,0163532298",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,56",Deleterious,0,Damaging,"34,49","33,42"
"low freq, many artifacts",UPN2_044,2,198267672,C,T,splice_donor_variant+intron_variant(HIGH|||c.1806+1G>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|13|T),5591,61,5678,"0,0107432194",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,,,,,"31,49","33,18"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,198267673,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys602Asn/c.1806G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|13|A),20125,213,20390,"0,0104462972",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,52",Deleterious,27,Damaging,"28,92","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,198267673,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys602Asn/c.1806G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|13|A),14784,156,14970,"0,0104208417",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,52",Deleterious,27,Damaging,"29,02","15,57"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,198267673,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys602Asn/c.1806G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|13|A),19603,215,19856,"0,0108279613",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,52",Deleterious,27,Damaging,"29,03","14,85"
"low bq, low freq, many artifacts",UPN2_055,2,198267673,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys602Asn/c.1806G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|13|A),23514,246,23840,"0,0103187919",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,52",Deleterious,27,Damaging,"29,07","14,58"
"low freq, many artifacts",UPN2_056,2,198267675,T,C,missense_variant+splice_region_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys602Glu/c.1804A>G|1304|SF3B1|protein_coding|CODING|ENST00000335508|13|C),2407,28,2443,"0,0114613181",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,62",Deleterious,"0,001",Damaging,"31,84","31,82"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,198267678,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala601Ser/c.1801G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|13|A),19525,204,19842,"0,0102812217",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,79",Neutral,689,Tolerated,"28,68","16,82"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,198267678,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala601Ser/c.1801G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|13|A),24361,251,24683,"0,0101689422",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,79",Neutral,689,Tolerated,"28,8","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,198267678,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala601Ser/c.1801G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|13|A),26933,279,27283,"0,0102261482",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,79",Neutral,689,Tolerated,"28,79","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_067,2,198267678,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala601Ser/c.1801G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|13|A),64461,675,65299,"0,0103370649",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,79",Neutral,689,Tolerated,"28,74","15,69"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,198267678,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala601Ser/c.1801G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|13|A),34957,358,35382,"0,0101181392",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,79",Neutral,689,Tolerated,"28,79","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,198267678,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala601Ser/c.1801G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|13|A),23782,242,24090,"0,0100456621",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,79",Neutral,689,Tolerated,"28,65","15,35"
"low bq, low freq, many artifacts",UPN2_082,2,198267678,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala601Ser/c.1801G>T|1304|SF3B1|protein_coding|CODING|ENST00000335508|13|A),44367,470,44949,"0,0104562949",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,79",Neutral,689,Tolerated,"28,74","15,33"
"low freq, many artifacts",UPN2_056,2,198267678,C,T,missense_variant(MODERATE|MISSENSE|Gca/Aca|p.Ala601Thr/c.1801G>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|13|T),2376,40,2443,"0,0163733115",0,0,0,0,1,1,0,1,3,NO,NO,COSM2905675,large_intestine,1,NO,NO,NO,NO,NO,NO,"-2,34",Neutral,"0,25",Tolerated,"28,58","34,3"
"low bq, low freq, many artifacts",UPN2_044,2,198267689,A,T,missense_variant(MODERATE|MISSENSE|aTt/aAt|p.Ile597Asn/c.1790T>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|13|T),2767,29,2814,"0,0103056148",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,3",Deleterious,0,Damaging,"31,68","22,21"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,198267707,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val591Glu/c.1772T>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|13|T),8835,91,8954,"0,0101630556",0,0,0,0,1,0,0,0,1,NO,NO,COSM1736900,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"-5,16",Deleterious,22,Damaging,"33,85","20,33"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,198267707,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val591Glu/c.1772T>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|13|T),8310,86,8427,"0,0102052925",0,0,0,0,1,0,0,0,1,NO,NO,COSM1736900,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"-5,16",Deleterious,22,Damaging,"34,04","22,02"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,198267707,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val591Glu/c.1772T>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|13|T),2773,29,2818,"0,0102909865",0,0,0,0,1,0,0,0,1,NO,NO,COSM1736900,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"-5,16",Deleterious,22,Damaging,"33,89","18,14"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,198267707,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val591Glu/c.1772T>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|13|T),9477,102,9614,"0,0106095278",0,0,0,0,1,0,0,0,1,NO,NO,COSM1736900,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"-5,16",Deleterious,22,Damaging,"34,06","19,24"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,198267707,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val591Glu/c.1772T>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|13|T),12150,129,12330,"0,0104622871",0,0,0,0,1,0,0,0,1,NO,NO,COSM1736900,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"-5,16",Deleterious,22,Damaging,"34,12","22,48"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,198267707,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val591Glu/c.1772T>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|13|T),11685,144,11856,"0,012145749",0,0,0,0,1,0,0,0,1,NO,NO,COSM1736900,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"-5,16",Deleterious,22,Damaging,"34,02","20,6"
"low bq, low freq, many artifacts",UPN2_056,2,198267707,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val591Glu/c.1772T>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|13|T),1193,20,1217,"0,0164338537",0,0,0,0,1,0,0,1,2,NO,NO,COSM1736900,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"-5,16",Deleterious,"0,022",Damaging,"33,93","25,5"
"low bq, low freq, many artifacts",UPN2_057,2,198267707,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val591Glu/c.1772T>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|13|T),14442,166,14641,"0,0113380234",0,0,0,0,1,0,0,0,1,NO,NO,COSM1736900,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"-5,16",Deleterious,22,Damaging,"33,94","22,7"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,198267715,A,T,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr588*/c.1764T>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|13|T),8820,104,8956,"0,0116123269",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,56","21,41"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,198267715,A,T,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr588*/c.1764T>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|13|T),9964,113,10130,"0,0111549852",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,55","18,35"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,198267715,A,T,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr588*/c.1764T>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|13|T),7342,78,7450,"0,0104697987",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,59","21,95"
"low freq, many artifacts, many samples",UPN2_044,2,198267717,A,T,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr588Asn/c.1762T>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|13|T),2784,34,2820,"0,0120567376",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,04",Deleterious,2,Damaging,"34,28","27,94"
"low freq, many artifacts",UPN2_006,2,198267726,C,T,missense_variant(MODERATE|MISSENSE|Gaa/Aaa|p.Glu585Lys/c.1753G>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|13|T),5822,66,5898,"0,011190234",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,"0,009",Damaging,"34,69","29,56"
"low freq, many artifacts",UPN2_044,2,198267752,A,G,missense_variant(MODERATE|MISSENSE|gTg/gCg|p.Val576Ala/c.1727T>C|1304|SF3B1|protein_coding|CODING|ENST00000335508|13|G),2771,30,2825,"0,010619469",0,0,0,0,1,0,0,1,2,NO,NO,COSM4913926,liver,1,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,"0,014",Damaging,"34,52","33,7"
"low freq, many artifacts",UPN2_044,2,198267755,A,T,missense_variant(MODERATE|MISSENSE|cTc/cAc|p.Leu575His/c.1724T>A|1304|SF3B1|protein_coding|CODING|ENST00000335508|13|T),2778,37,2824,"0,013101983",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,32",Deleterious,0,Damaging,"34,73","27,95"
"low bq, low freq, many artifacts, many samples",UPN2_012,2,209113135,C,A,missense_variant(MODERATE|MISSENSE|tgG/tgT|p.Trp124Cys/c.372G>T|414|IDH1|protein_coding|CODING|ENST00000345146|4|A),6566,69,6651,"0,0103743798",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-11,25",Deleterious,25,Damaging,"33,33","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_063,2,209113135,C,A,missense_variant(MODERATE|MISSENSE|tgG/tgT|p.Trp124Cys/c.372G>T|414|IDH1|protein_coding|CODING|ENST00000345146|4|A),5186,53,5246,"0,0101029356",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-11,25",Deleterious,25,Damaging,"31,9","16,04"
"low bq, low freq, many artifacts, many samples",UPN2_067,2,209113135,C,A,missense_variant(MODERATE|MISSENSE|tgG/tgT|p.Trp124Cys/c.372G>T|414|IDH1|protein_coding|CODING|ENST00000345146|4|A),18986,216,19219,"0,0112388782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-11,25",Deleterious,25,Damaging,"31,84","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,209113135,C,A,missense_variant(MODERATE|MISSENSE|tgG/tgT|p.Trp124Cys/c.372G>T|414|IDH1|protein_coding|CODING|ENST00000345146|4|A),2350,29,2383,"0,0121695342",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-11,25",Deleterious,25,Damaging,"31,88","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,209113135,C,A,missense_variant(MODERATE|MISSENSE|tgG/tgT|p.Trp124Cys/c.372G>T|414|IDH1|protein_coding|CODING|ENST00000345146|4|A),3943,46,3999,"0,0115028757",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-11,25",Deleterious,25,Damaging,"31,86","16,78"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,209113135,C,A,missense_variant(MODERATE|MISSENSE|tgG/tgT|p.Trp124Cys/c.372G>T|414|IDH1|protein_coding|CODING|ENST00000345146|4|A),6974,71,7061,"0,010055233",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-11,25",Deleterious,25,Damaging,"31,94","15,42"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,209113135,C,A,missense_variant(MODERATE|MISSENSE|tgG/tgT|p.Trp124Cys/c.372G>T|414|IDH1|protein_coding|CODING|ENST00000345146|4|A),5969,65,6038,"0,010765154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-11,25",Deleterious,25,Damaging,"31,82","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,209113135,C,A,missense_variant(MODERATE|MISSENSE|tgG/tgT|p.Trp124Cys/c.372G>T|414|IDH1|protein_coding|CODING|ENST00000345146|4|A),3781,56,3861,"0,0145040145",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-11,25",Deleterious,25,Damaging,"31,79","15,57"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,209113135,C,A,missense_variant(MODERATE|MISSENSE|tgG/tgT|p.Trp124Cys/c.372G>T|414|IDH1|protein_coding|CODING|ENST00000345146|4|A),14820,155,15025,"0,0103161398",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-11,25",Deleterious,25,Damaging,"31,83","15,79"
"low bq, low freq, many artifacts",UPN2_085,2,209113135,C,A,missense_variant(MODERATE|MISSENSE|tgG/tgT|p.Trp124Cys/c.372G>T|414|IDH1|protein_coding|CODING|ENST00000345146|4|A),12900,141,13060,"0,0107963247",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-11,25",Deleterious,25,Damaging,"31,91","16,44"
"low freq, many artifacts",UPN2_044,2,209113151,C,T,missense_variant(MODERATE|MISSENSE|cGg/cAg|p.Arg119Gln/c.356G>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),5691,89,5818,"0,015297353",0,0,0,0,1,1,0,1,3,NO,NO,COSM242544,prostate,1,NO,NO,NO,"7,41E-005",NO,NO,"-3,23",Deleterious,"0,004",Damaging,"30,37","33,31"
"low bq, low freq, many artifacts, many samples",UPN2_056,2,209113154,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro118His/c.353C>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),1831,21,1857,"0,0113085622",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,03",Deleterious,0,Damaging,"29,22","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_059,2,209113154,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro118His/c.353C>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),9586,102,9743,"0,0104690547",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,03",Deleterious,0,Damaging,"28,17","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,209113154,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro118His/c.353C>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),16796,174,17052,"0,0102040816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,03",Deleterious,0,Damaging,"28,03","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_067,2,209113154,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro118His/c.353C>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),37064,432,37690,"0,0114619262",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,03",Deleterious,0,Damaging,"28,14","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,209113154,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro118His/c.353C>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),20850,237,21196,"0,011181355",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,03",Deleterious,0,Damaging,"28,21","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,209113154,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro118His/c.353C>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),16170,174,16430,"0,0105903834",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,03",Deleterious,0,Damaging,"28,14","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,209113154,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro118His/c.353C>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),10208,112,10371,"0,0107993443",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,03",Deleterious,0,Damaging,"28,13","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_071,2,209113154,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro118His/c.353C>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),4632,49,4710,"0,010403397",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,03",Deleterious,0,Damaging,"28,04","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_072,2,209113154,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro118His/c.353C>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),5704,73,5797,"0,0125927204",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,03",Deleterious,0,Damaging,"28,11","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_073,2,209113154,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro118His/c.353C>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),7742,93,7884,"0,0117960426",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,03",Deleterious,0,Damaging,"28,25","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,209113154,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro118His/c.353C>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),13687,156,13893,"0,0112286763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,03",Deleterious,0,Damaging,"27,92","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,209113154,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro118His/c.353C>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),11700,125,11883,"0,0105192292",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,03",Deleterious,0,Damaging,"28,09","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_076,2,209113154,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro118His/c.353C>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),11580,128,11782,"0,0108640299",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,03",Deleterious,0,Damaging,"28,14","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_078,2,209113154,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro118His/c.353C>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),9757,105,9941,"0,0105623177",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,03",Deleterious,0,Damaging,"28,03","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_080,2,209113154,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro118His/c.353C>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),7349,90,7470,"0,0120481928",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,03",Deleterious,0,Damaging,"28,09","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,209113154,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro118His/c.353C>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),7441,87,7560,"0,0115079365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,03",Deleterious,0,Damaging,"28,03","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,209113154,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro118His/c.353C>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),29036,311,29508,"0,0105395147",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,03",Deleterious,0,Damaging,"28,05","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_084,2,209113154,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro118His/c.353C>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),19076,220,19390,"0,0113460547",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,03",Deleterious,0,Damaging,"28,2","15,56"
"low bq, low freq, many artifacts, many samples",UPN2_086,2,209113154,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro118His/c.353C>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),23589,258,23971,"0,0107630053",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,03",Deleterious,0,Damaging,"28,14","15,23"
"low bq, low freq, many artifacts",UPN2_087,2,209113154,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro118His/c.353C>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),22322,274,22716,"0,0120619827",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,03",Deleterious,0,Damaging,"28,16","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_060,2,209113155,G,T,missense_variant(MODERATE|MISSENSE|Ccc/Acc|p.Pro118Thr/c.352C>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),10061,114,10227,"0,0111469639",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,14",Deleterious,0,Damaging,"29,16","15,34"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,209113155,G,T,missense_variant(MODERATE|MISSENSE|Ccc/Acc|p.Pro118Thr/c.352C>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),8471,98,8601,"0,011394024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,14",Deleterious,0,Damaging,"28,97","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_064,2,209113155,G,T,missense_variant(MODERATE|MISSENSE|Ccc/Acc|p.Pro118Thr/c.352C>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),9461,101,9608,"0,0105120733",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,14",Deleterious,0,Damaging,"28,96","15,97"
"low bq, low freq, many artifacts, many samples",UPN2_065,2,209113155,G,T,missense_variant(MODERATE|MISSENSE|Ccc/Acc|p.Pro118Thr/c.352C>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),16805,174,17062,"0,010198101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,14",Deleterious,0,Damaging,"28,93","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_066,2,209113155,G,T,missense_variant(MODERATE|MISSENSE|Ccc/Acc|p.Pro118Thr/c.352C>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),33429,370,33912,"0,0109105921",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,14",Deleterious,0,Damaging,"28,94","15,46"
"low bq, low freq, many artifacts, many samples",UPN2_068,2,209113155,G,T,missense_variant(MODERATE|MISSENSE|Ccc/Acc|p.Pro118Thr/c.352C>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),20859,226,21212,"0,0106543466",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,14",Deleterious,0,Damaging,"29,05","16,64"
"low bq, low freq, many artifacts, many samples",UPN2_069,2,209113155,G,T,missense_variant(MODERATE|MISSENSE|Ccc/Acc|p.Pro118Thr/c.352C>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),16190,167,16447,"0,0101538274",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,14",Deleterious,0,Damaging,"28,99","15,4"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,209113155,G,T,missense_variant(MODERATE|MISSENSE|Ccc/Acc|p.Pro118Thr/c.352C>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),10210,124,10385,"0,0119402985",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,14",Deleterious,0,Damaging,"29,01","15,89"
"low bq, low freq, many artifacts, many samples",UPN2_074,2,209113155,G,T,missense_variant(MODERATE|MISSENSE|Ccc/Acc|p.Pro118Thr/c.352C>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),13694,155,13902,"0,0111494749",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,14",Deleterious,0,Damaging,"28,89","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_075,2,209113155,G,T,missense_variant(MODERATE|MISSENSE|Ccc/Acc|p.Pro118Thr/c.352C>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),11703,135,11897,"0,0113473985",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,14",Deleterious,0,Damaging,"28,93","17,18"
"low bq, low freq, many artifacts, many samples",UPN2_077,2,209113155,G,T,missense_variant(MODERATE|MISSENSE|Ccc/Acc|p.Pro118Thr/c.352C>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),17808,204,18082,"0,0112819378",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,14",Deleterious,0,Damaging,"28,92","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_081,2,209113155,G,T,missense_variant(MODERATE|MISSENSE|Ccc/Acc|p.Pro118Thr/c.352C>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),7445,91,7572,"0,0120179609",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,14",Deleterious,0,Damaging,"28,78","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_082,2,209113155,G,T,missense_variant(MODERATE|MISSENSE|Ccc/Acc|p.Pro118Thr/c.352C>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),29038,335,29532,"0,0113436273",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,14",Deleterious,0,Damaging,"28,92","15,74"
"low bq, low freq, many artifacts",UPN2_085,2,209113155,G,T,missense_variant(MODERATE|MISSENSE|Ccc/Acc|p.Pro118Thr/c.352C>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),25290,289,25706,"0,0112425115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,14",Deleterious,0,Damaging,"28,94","15,92"
"low freq, many artifacts",UPN2_044,2,209113181,C,T,missense_variant(MODERATE|MISSENSE|aGa/aAa|p.Arg109Lys/c.326G>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),5732,107,5860,"0,0182593857",0,0,0,0,1,1,0,1,3,NO,NO,COSM573095,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,0,Damaging,"33,31","34,28"
"low bq, low freq, many artifacts",UPN2_006,2,209113191,T,A,missense_variant(MODERATE|MISSENSE|Acg/Tcg|p.Thr106Ser/c.316A>T|414|IDH1|protein_coding|CODING|ENST00000345146|4|A),9772,120,9944,"0,0120675784",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,"0,001",Damaging,"32,52","26,45"
"low bq, low freq, many artifacts",UPN2_049,2,209113211,A,T,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile99Lys/c.296T>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),14656,150,14877,"0,010082678",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,19",Deleterious,0,Damaging,"32,26","20,65"
"low freq, many artifacts",UPN2_006,2,209113217,C,T,missense_variant(MODERATE|MISSENSE|gGc/gAc|p.Gly97Asp/c.290G>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),4873,61,4950,"0,0123232323",0,0,0,0,1,0,0,1,2,NO,NO,COSM1669702,large_intestine,4,NO,NO,NO,NO,NO,NO,"-6,24",Deleterious,0,Damaging,"34,13","30,85"
"low bq, low freq, many artifacts, many samples",UPN2_002,2,209113219,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn96Lys/c.288T>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),5840,77,5927,"0,0129913953",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,0,Damaging,"34,41","20,3"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,209113219,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn96Lys/c.288T>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),9778,123,9935,"0,0123804731",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,0,Damaging,"33,86","18,85"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,209113219,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn96Lys/c.288T>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),8300,91,8428,"0,0107973422",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,0,Damaging,"33,89","19,47"
"low bq, low freq, many artifacts, many samples",UPN2_005,2,209113219,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn96Lys/c.288T>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),1808,20,1833,"0,0109110747",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,0,Damaging,"34,34","20,4"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,209113219,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn96Lys/c.288T>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),13448,152,13660,"0,0111273792",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,0,Damaging,"33,88","18,14"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,209113219,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn96Lys/c.288T>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),7294,76,7398,"0,0102730468",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,0,Damaging,"33,85","17,63"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,209113219,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn96Lys/c.288T>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),11171,121,11327,"0,0106824402",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,0,Damaging,"33,78","16,69"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,209113219,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn96Lys/c.288T>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),8592,111,8741,"0,0126987759",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,0,Damaging,"33,86","17,28"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,209113219,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn96Lys/c.288T>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),13110,150,13311,"0,0112688754",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,0,Damaging,"33,89","17,81"
"low bq, low freq, many artifacts, many samples",UPN2_010,2,209113219,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn96Lys/c.288T>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),10438,117,10586,"0,0110523333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,0,Damaging,"34,42","21,02"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,209113219,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn96Lys/c.288T>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),12191,145,12381,"0,0117114934",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,0,Damaging,"33,82","18,22"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,209113219,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn96Lys/c.288T>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),11207,137,11381,"0,0120376065",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,0,Damaging,"33,9","19,67"
"low bq, low freq, many artifacts, many samples",UPN2_058,2,209113219,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn96Lys/c.288T>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),11605,135,11775,"0,0114649682",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,0,Damaging,"33,95","19,09"
"low bq, low freq, many artifacts, many samples",UPN2_013,2,209113219,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn96Lys/c.288T>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),3403,41,3449,"0,0118875036",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,0,Damaging,"34,32","20,07"
"low bq, low freq, many artifacts, many samples",UPN2_062,2,209113219,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn96Lys/c.288T>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),4234,44,4293,"0,010249243",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,0,Damaging,"33,87","17,41"
"low bq, low freq, many artifacts, many samples",UPN2_070,2,209113219,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn96Lys/c.288T>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),5132,57,5203,"0,0109552181",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,0,Damaging,"33,95","17,91"
"low bq, low freq, many artifacts",UPN2_081,2,209113219,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn96Lys/c.288T>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),3733,46,3786,"0,0121500264",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,0,Damaging,34,"18,7"
"low bq, low freq, many artifacts",UPN2_044,2,209113223,G,T,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro95Gln/c.284C>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),2872,31,2911,"0,0106492614",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,14",Deleterious,0,Damaging,"33,91","23,65"
"low bq, low freq, many artifacts, many samples",UPN2_042,2,209113233,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp92Arg/c.274T>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),9795,113,9938,"0,0113704971",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-12,03",Deleterious,0,Damaging,"34,12","22,8"
"low bq, low freq, many artifacts, many samples",UPN2_043,2,209113233,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp92Arg/c.274T>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),8290,99,8434,"0,0117382025",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-12,03",Deleterious,0,Damaging,"34,23","21,17"
"low bq, low freq, many artifacts, many samples",UPN2_044,2,209113233,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp92Arg/c.274T>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),2860,39,2912,"0,0133928571",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-12,03",Deleterious,0,Damaging,"34,19","21,92"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,209113233,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp92Arg/c.274T>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),13449,148,13667,"0,0108290042",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-12,03",Deleterious,0,Damaging,"34,07","21,43"
"low bq, low freq, many artifacts, many samples",UPN2_046,2,209113233,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp92Arg/c.274T>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),11360,125,11525,"0,010845987",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-12,03",Deleterious,0,Damaging,"34,12","20,45"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,209113233,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp92Arg/c.274T>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),10631,118,10785,"0,0109411219",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-12,03",Deleterious,0,Damaging,"34,21","20,11"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,209113233,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp92Arg/c.274T>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),7287,88,7406,"0,0118822576",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-12,03",Deleterious,0,Damaging,"34,13","20,19"
"low bq, low freq, many artifacts, many samples",UPN2_050,2,209113233,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp92Arg/c.274T>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),11163,130,11329,"0,0114749757",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-12,03",Deleterious,0,Damaging,34,"20,7"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,209113233,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp92Arg/c.274T>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),8594,114,8742,"0,0130404942",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-12,03",Deleterious,0,Damaging,"34,1","20,64"
"low bq, low freq, many artifacts, many samples",UPN2_053,2,209113233,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp92Arg/c.274T>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),13118,141,13314,"0,010590356",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-12,03",Deleterious,0,Damaging,"34,16","21,09"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,209113233,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp92Arg/c.274T>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),8607,93,8732,"0,010650481",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-12,03",Deleterious,0,Damaging,"34,02","20,81"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,209113233,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp92Arg/c.274T>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),12196,138,12391,"0,0111371156",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-12,03",Deleterious,0,Damaging,"34,13","20,76"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,209113233,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp92Arg/c.274T>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),11197,143,11393,"0,0125515668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-12,03",Deleterious,0,Damaging,"34,19","20,78"
"low bq, low freq, many artifacts",UPN2_058,2,209113233,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp92Arg/c.274T>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),11596,146,11779,"0,0123949401",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-12,03",Deleterious,0,Damaging,"34,07","20,65"
"low bq, low freq, many artifacts, many samples",UPN2_049,2,209113235,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met91Lys/c.272T>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),7289,90,7406,"0,0121523089",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,0,Damaging,"34,26","19,99"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,209113235,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met91Lys/c.272T>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),8607,100,8742,"0,01143903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,0,Damaging,"34,21","20,18"
"low bq, low freq, many artifacts, many samples",UPN2_054,2,209113235,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met91Lys/c.272T>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),8601,92,8732,"0,0105359597",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,0,Damaging,"34,11","19,74"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,209113235,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met91Lys/c.272T>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),12215,129,12391,"0,010410782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,0,Damaging,"34,14","22,2"
"low bq, low freq, many artifacts",UPN2_071,2,209113235,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met91Lys/c.272T>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),2320,24,2355,"0,0101910828",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,0,Damaging,"34,5","24,38"
"low freq, many artifacts",UPN2_056,2,209113271,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp79Val/c.236A>T|414|IDH1|protein_coding|CODING|ENST00000345146|4|A),3137,35,3185,"0,010989011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,23",Deleterious,0,Damaging,"35,16","28,97"
"low freq, many artifacts",UPN2_056,2,209113284,T,A,missense_variant(MODERATE|MISSENSE|Act/Tct|p.Thr75Ser/c.223A>T|414|IDH1|protein_coding|CODING|ENST00000345146|4|A),3127,32,3185,"0,0100470958",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,65",Deleterious,0,Damaging,"34,94","30,09"
inspected,UPN2_041,2,209113292,T,C,missense_variant(MODERATE|MISSENSE|aAa/aGa|p.Lys72Arg/c.215A>G|414|IDH1|protein_coding|CODING|ENST00000345146|4|C),584,25,612,"0,0408496732",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,0,Damaging,"34,6","35,28"
"low freq, many artifacts",UPN2_044,2,209113293,T,G,missense_variant(MODERATE|MISSENSE|Aaa/Caa|p.Lys72Gln/c.214A>C|414|IDH1|protein_coding|CODING|ENST00000345146|4|G),3905,48,3982,"0,0120542441",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,65",Deleterious,0,Damaging,"32,57","31,4"
"low bq, low freq, many artifacts, many samples",UPN2_045,2,209113307,T,A,missense_variant(MODERATE|MISSENSE|cAt/cTt|p.His67Leu/c.200A>T|414|IDH1|protein_coding|CODING|ENST00000345146|4|A),3777,39,3834,"0,010172144",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,94",Deleterious,16,Damaging,"34,25","19,54"
"low bq, low freq, many artifacts, many samples",UPN2_056,2,209113307,T,A,missense_variant(MODERATE|MISSENSE|cAt/cTt|p.His67Leu/c.200A>T|414|IDH1|protein_coding|CODING|ENST00000345146|4|A),2231,23,2257,"0,0101905184",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,94",Deleterious,16,Damaging,"34,34","21,3"
"low bq, low freq, many artifacts, many samples",UPN2_057,2,209113307,T,A,missense_variant(MODERATE|MISSENSE|cAt/cTt|p.His67Leu/c.200A>T|414|IDH1|protein_coding|CODING|ENST00000345146|4|A),5302,56,5378,"0,0104127929",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,94",Deleterious,16,Damaging,"34,36","18,95"
"low freq, many artifacts",UPN2_043,2,209113313,T,C,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys65Arg/c.194A>G|414|IDH1|protein_coding|CODING|ENST00000345146|4|C),3039,32,3105,"0,0103059581",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,19",Neutral,"0,235",Tolerated,"34,38","34,94"
"low bq, low freq, many artifacts, many samples",UPN2_052,2,209113317,T,A,missense_variant(MODERATE|MISSENSE|Ata/Tta|p.Ile64Leu/c.190A>T|414|IDH1|protein_coding|CODING|ENST00000345146|4|A),4028,42,4079,"0,0102966413",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,8,Damaging,"34,77","26,81"
"low bq, low freq, many artifacts, many samples",UPN2_047,2,209113321,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu62Asp/c.186A>T|414|IDH1|protein_coding|CODING|ENST00000345146|4|A),6200,64,6302,"0,0101555062",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,79",Neutral,22,Damaging,"33,73","23,02"
"low freq, many artifacts",UPN2_006,2,209113326,C,T,missense_variant(MODERATE|MISSENSE|Gca/Aca|p.Ala61Thr/c.181G>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),1912,28,1946,"0,0143884892",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,58",Deleterious,0,Damaging,"34,93","34,75"
"low bq, low freq, many artifacts, many samples",UPN2_048,2,209113335,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys58*/c.172A>T|414|IDH1|protein_coding|CODING|ENST00000345146|4|A),2850,30,2893,"0,0103698583",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,45","22,53"
"low bq, low freq, many artifacts, many samples",UPN2_051,2,209113335,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys58*/c.172A>T|414|IDH1|protein_coding|CODING|ENST00000345146|4|A),4672,52,4743,"0,0109635252",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,55",19
"low bq, low freq, many artifacts, many samples",UPN2_053,2,209113335,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys58*/c.172A>T|414|IDH1|protein_coding|CODING|ENST00000345146|4|A),4977,51,5053,"0,0100930141",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,43","20,63"
"low bq, low freq, many artifacts, many samples",UPN2_055,2,209113335,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys58*/c.172A>T|414|IDH1|protein_coding|CODING|ENST00000345146|4|A),4908,50,4981,"0,010038145",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,42","17,56"
"low bq, low freq, many artifacts",UPN2_057,2,209113335,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys58*/c.172A>T|414|IDH1|protein_coding|CODING|ENST00000345146|4|A),5327,54,5395,"0,0100092678",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,54","17,46"
"inspected, many artifacts",UPN2_044,2,209113343,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln55Leu/c.164A>T|414|IDH1|protein_coding|CODING|ENST00000345146|4|A),2092,70,2170,"0,0322580645",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,"0,001",Damaging,"32,54","30,21"
"low bq, low freq, many artifacts",UPN2_056,2,209113343,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln55Leu/c.164A>T|414|IDH1|protein_coding|CODING|ENST00000345146|4|A),4499,46,4549,"0,0101121126",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,1,Damaging,"32,51","25,85"
"low freq, many artifacts",UPN2_056,2,209113344,G,A,stop_gained(HIGH|NONSENSE|Caa/Taa|p.Gln55*/c.163C>T|414|IDH1|protein_coding|CODING|ENST00000345146|4|A),4453,55,4549,"0,0120905694",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,75","32,69"
"low freq, many artifacts",UPN2_044,2,209113353,T,A,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr52Ser/c.154A>T|414|IDH1|protein_coding|CODING|ENST00000345146|4|A),2114,38,2171,"0,0175034546",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,56",Deleterious,"0,008",Damaging,"31,9","31,32"
"low freq, many artifacts",UPN2_050,2,209113353,T,A,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr52Ser/c.154A>T|414|IDH1|protein_coding|CODING|ENST00000345146|4|A),8934,96,9060,"0,0105960265",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,56",Deleterious,"0,008",Damaging,"32,16","31,08"
"low freq, many artifacts",UPN2_044,2,209113363,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn48Lys/c.144T>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),2137,25,2171,"0,0115154307",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,"0,08",Tolerated,"33,9","30,04"
"low freq, many artifacts",UPN2_056,2,209113364,T,C,missense_variant(MODERATE|MISSENSE|aAt/aGt|p.Asn48Ser/c.143A>G|414|IDH1|protein_coding|CODING|ENST00000345146|4|C),4466,53,4548,"0,0116534741",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,119",Tolerated,"32,79","32,83"
"low bq, low freq, many artifacts",UPN2_043,2,209113371,T,A,missense_variant(MODERATE|MISSENSE|Ata/Tta|p.Ile46Leu/c.136A>T|414|IDH1|protein_coding|CODING|ENST00000345146|4|A),6161,63,6257,"0,010068723",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,22",Neutral,789,Tolerated,"32,64","21,38"
"low freq, many artifacts",UPN2_006,2,209113375,T,A,missense_variant(MODERATE|MISSENSE|ttA/ttT|p.Leu44Phe/c.132A>T|414|IDH1|protein_coding|CODING|ENST00000345146|4|A),3852,50,3914,"0,0127746551",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,34",Deleterious,"0,001",Damaging,"34,46","31,88"
"low freq, many artifacts",UPN2_006,2,209113381,A,T,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr42*/c.126T>A|414|IDH1|protein_coding|CODING|ENST00000345146|4|T),3855,43,3914,"0,0109862034",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,58","33,12"
"low bq, low freq, many artifacts, many samples",UPN2_017,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),7636,101,7750,"0,0130322581",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"31,21","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_020,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),9435,139,9598,"0,0144821838",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"31,19","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_021,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),11605,229,11844,"0,0193346842",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"30,2","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_024,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),8330,93,8432,"0,0110294118",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"31,28","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_089,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),13405,233,13653,"0,0170658463",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"30,75","15,4"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),7895,119,8021,"0,0148360554",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"31,22","15,76"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),12391,150,12567,"0,0119360229",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"31,15","16,92"
"low bq, low freq, many artifacts, many samples",UPN2_029,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),17751,217,17986,"0,0120649394",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"31,1","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_030,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),17206,367,17604,"0,0208475347",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"30,16","15,17"
"low bq, low freq, many artifacts, many samples",UPN2_031,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),11114,223,11362,"0,0196268263",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"30,31","15,79"
"low bq, low freq, many artifacts, many samples",UPN2_032,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),6507,137,6663,"0,0205613087",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"30,04","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_046,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),17576,196,17804,"0,0110087621",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"31,11","15,46"
"low bq, many samples",UPN2_047,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),8048,263,8330,"0,0315726291",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"29,31","15,74"
"low bq, many samples",UPN2_036,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),30367,713,31120,"0,0229113111",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"30,05","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_037,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),22408,257,22700,"0,0113215859",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"31,15","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),17215,252,17523,"0,0143810991",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"30,42","15,9"
"low bq, low freq, many artifacts, many samples",UPN2_038,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),31688,356,32107,"0,0110879248",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"31,28","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_039,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),27360,363,27781,"0,0130664843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"30,99","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_054,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),13897,167,14091,"0,0118515364",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"30,66","16,1"
"low bq, low freq, many artifacts, many samples",UPN2_007,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),25384,348,25766,"0,0135061709",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"30,76","15,17"
"low bq, low freq, many artifacts, many samples",UPN2_008,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),32416,379,32832,"0,011543616",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"30,88","15,24"
"low bq, many samples",UPN2_056,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),984,27,1011,"0,0267062315",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"29,58",14
"low bq, low freq, many artifacts, many samples",UPN2_090,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),8626,103,8751,"0,0117700834",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"31,14","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_057,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),19160,396,19601,"0,0202030509",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"30,17","15,73"
"low bq, many samples",UPN2_059,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),2433,87,2525,"0,0344554455",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"30,79","15,41"
"low bq, low freq, many artifacts, many samples",UPN2_091,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2003|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),8575,122,8709,"0,014008497",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"31,21","15,02"
"low bq, many samples",UPN2_092,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),7149,190,7345,"0,0258679374",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"29,75","14,58"
"low bq, many samples",UPN2_093,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),9648,262,9932,"0,0263793798",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"30,25","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_061,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),17035,180,17240,"0,0104408353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"31,35","15,64"
"low bq, low freq, many artifacts, many samples",UPN2_063,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),14349,317,14688,"0,021582244",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"30,77","15,7"
"low bq, low freq, many artifacts, many samples",UPN2_064,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),3296,72,3371,"0,0213586473",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"31,13","16,36"
"low bq, many samples",UPN2_065,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),4052,120,4181,"0,0287012676",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"30,93","15,8"
"low bq, many samples",UPN2_066,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),9286,449,9741,"0,0460938302",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"29,91","15,68"
"low bq, many samples",UPN2_067,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),11979,288,12288,"0,0234375",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"31,07","15,6"
"low bq, low freq, many artifacts, many samples",UPN2_068,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),12101,208,12333,"0,0168653207",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"31,2",17
"low bq, low freq, many artifacts, many samples",UPN2_070,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),10835,151,11008,"0,0137172965",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"31,21","15,85"
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),10758,124,10895,"0,0113813676",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"31,18","15,81"
"low bq, many samples",UPN2_073,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),4028,115,4154,"0,0276841598",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"31,04","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_075,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),17321,386,17753,"0,021742804",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"30,82","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_076,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),14511,154,14687,"0,0104854633",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"31,29","15,86"
"low bq, low freq, many artifacts, many samples",UPN2_077,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),13760,208,13992,"0,0148656375",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"31,23","16,02"
"low bq, low freq, many artifacts, many samples",UPN2_080,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),12192,133,12344,"0,0107744653",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"31,28","15,62"
"low bq, many samples",UPN2_082,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),11050,475,11544,"0,0411469161",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,30,"15,97"
"low bq, low freq, many artifacts, many samples",UPN2_083,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),18882,224,19148,"0,0116983497",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"31,29","16,07"
"low bq, low freq, many artifacts, many samples",UPN2_084,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),19803,287,20140,"0,0142502483",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"31,16","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_085,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),10219,227,10473,"0,0216747828",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"31,16","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_086,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),7159,145,7312,"0,0198304158",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"31,05","15,97"
"low bq, many samples",UPN2_088,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),10600,347,10968,"0,0316374909",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"30,62","15,89"
"low bq, low freq, many artifacts, many samples",UPN2_094,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2000|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),8979,94,9092,"0,0103387593",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"31,35","15,51"
"low bq, low freq, many artifacts, many samples",UPN2_097,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),10359,123,10507,"0,0117064814",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"31,4","15,34"
"low bq, low freq, many artifacts, many samples",UPN2_100,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),11332,149,11490,"0,0129677981",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"30,87","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_101,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),10924,192,11131,"0,0172491241",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"30,5","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_102,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),13852,170,14042,"0,0121065375",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"31,31","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_105,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),9481,131,9617,"0,0136217116",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"30,82","15,28"
"low bq, many samples",UPN2_107,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),17780,497,18298,"0,0271614384",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"30,21","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_109,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),15239,248,15507,"0,0159927775",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"30,69","15,01"
"low bq, low freq, many artifacts",UPN2_111,4,106155076,G,T,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-24G>T|2001|TET2|protein_coding|CODING|ENST00000380013|3|T|WARNING_TRANSCRIPT_MULTIPLE_STOP_CODONS),15726,169,15914,"0,0106195802",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,0,Damaging,"31,26","15,02"
"low freq, many artifacts",UPN2_026,4,106155102,G,A,start_lost(HIGH|MISSENSE|atG/atA|p.Met1?/c.3G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),16653,176,16874,"0,0104302477",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,0,Damaging,"35,32","35,71"
"low bq, bad alignment, low freq, many artifacts",UPN2_048,4,106155114,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg5Ser/c.15A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),1118,21,1143,"0,0183727034",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,27,Damaging,"26,03","14,33"
"low freq, many artifacts",UPN2_044,4,106155121,C,T,missense_variant(MODERATE|MISSENSE|Cat/Tat|p.His8Tyr/c.22C>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),3950,54,4010,"0,0134663342",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,61",Deleterious,0,Damaging,"35,29","35,83"
"low bq, bad alignment, many samples",UPN2_041,4,106155138,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg13Ser/c.39A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),721,20,745,"0,0268456376",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,23",Neutral,83,Tolerated,"26,15",14
"low bq, bad alignment, many samples",UPN2_048,4,106155138,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg13Ser/c.39A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),1103,27,1143,"0,0236220472",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,23",Neutral,83,Tolerated,"26,27","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_044,4,106155148,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe17Ile/c.49T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),4132,43,4186,"0,0102723364",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,2,Damaging,"32,61","22,86"
"low bq, many samples",UPN2_041,4,106155148,T,G,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe17Val/c.49T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),703,29,744,"0,0389784946",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,43",Neutral,2,Damaging,"27,41","14,93"
low bq,UPN2_048,4,106155148,T,G,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe17Val/c.49T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),1095,31,1143,"0,0271216098",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,43",Neutral,2,Damaging,"28,32","14,84"
low bq,UPN2_048,4,106155155,T,G,missense_variant(MODERATE|MISSENSE|aTa/aGa|p.Ile19Arg/c.56T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),1067,28,1116,"0,0250896057",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,57",Deleterious,0,Damaging,"28,47",14
"low bq, many samples",UPN2_041,4,106155172,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys25Ser/c.73T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),750,20,775,"0,0258064516",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,65",Deleterious,169,Tolerated,"32,16","15,9"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106155172,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys25Ser/c.73T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),3603,44,3668,"0,0119956379",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,65",Deleterious,169,Tolerated,"32,45","22,36"
"inspected, many artifacts",UPN2_047,4,106155175,C,A,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln26Lys/c.76C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),3581,76,3668,"0,0207197383",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,004",Damaging,"33,06","29,72"
"low bq, bad alignment, many samples",UPN2_048,4,106155178,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr27Pro/c.79A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),1068,37,1115,"0,0331838565",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,159,Tolerated,"25,77","14,35"
"low bq, bad alignment, many samples",UPN2_041,4,106155182,A,C,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu28Ala/c.83A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),728,41,774,"0,0529715762",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,22",Neutral,2,Damaging,"25,69","14,98"
"low bq, bad alignment",UPN2_048,4,106155182,A,C,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu28Ala/c.83A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),1064,37,1114,"0,0332136445",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,22",Neutral,2,Damaging,"25,4","14,57"
"low bq, bad alignment, many samples",UPN2_041,4,106155183,A,C,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu28Asp/c.84A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),720,24,774,"0,0310077519",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,5,Damaging,"22,82","14,92"
"low bq, bad alignment, many samples",UPN2_048,4,106155183,A,C,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu28Asp/c.84A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),1043,34,1114,"0,0305206463",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,5,Damaging,"22,58",14
"low bq, many samples",UPN2_041,4,106155188,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu30Gln/c.89T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),742,23,773,"0,0297542044",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,2,Damaging,"30,29","15,57"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106155188,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu30Gln/c.89T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),12593,128,12772,"0,010021923",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,2,Damaging,"33,29","23,62"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106155188,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu30Gln/c.89T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),3614,38,3667,"0,0103626943",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,2,Damaging,"33,01","18,32"
"low bq, low freq, many artifacts, many samples",UPN2_048,4,106155188,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu30Gln/c.89T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),1084,20,1115,"0,0179372197",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,2,Damaging,"30,54","16,4"
"low bq, low freq, many artifacts",UPN2_049,4,106155188,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu30Gln/c.89T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),4093,45,4149,"0,010845987",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,2,Damaging,"33,08","21,76"
low bq,UPN2_048,4,106155193,A,T,missense_variant(MODERATE|MISSENSE|Aca/Tca|p.Thr32Ser/c.94A>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),1069,31,1114,"0,0278276481",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,21,Damaging,"27,53","14,71"
"low bq, bad alignment, many samples",UPN2_041,4,106155197,A,C,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys33Thr/c.98A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),734,29,773,"0,0375161708",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,16",Neutral,4,Damaging,"25,57","14,45"
"low bq, bad alignment, many samples",UPN2_048,4,106155197,A,C,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys33Thr/c.98A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),1077,29,1113,"0,0260557053",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,16",Neutral,4,Damaging,"25,76",14
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106155207,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn36Lys/c.108T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),3591,50,3658,"0,0136686714",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,52",Deleterious,0,Damaging,"32,35","18,4"
low bq,UPN2_048,4,106155207,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn36Lys/c.108T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),1059,33,1108,"0,0297833935",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,52",Deleterious,0,Damaging,"28,27","14,79"
"low bq, bad alignment",UPN2_048,4,106155211,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser38Arg/c.112A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),1040,40,1105,"0,036199095",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,95",Neutral,1,Damaging,"24,43","15,43"
"low bq, low freq, many artifacts",UPN2_048,4,106155213,C,A,missense_variant(MODERATE|MISSENSE|agC/agA|p.Ser38Arg/c.114C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),1074,22,1105,"0,0199095023",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,95",Neutral,1,Damaging,"30,11","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_044,4,106155218,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu40Gln/c.119T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),7043,88,7167,"0,0122784987",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,4,Damaging,"31,5","18,68"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106155218,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu40Gln/c.119T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),8018,84,8133,"0,0103282921",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,4,Damaging,"31,49","19,67"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106155218,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu40Gln/c.119T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),26347,278,26758,"0,0103894162",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,4,Damaging,"31,53","19,18"
"low bq, low freq, many artifacts, many samples",UPN2_052,4,106155218,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu40Gln/c.119T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),18107,205,18433,"0,0111213584",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,4,Damaging,"31,59","18,39"
"low bq, low freq, many artifacts, many samples",UPN2_053,4,106155218,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu40Gln/c.119T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),31784,351,32270,"0,0108769755",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,4,Damaging,"31,56","18,64"
"low bq, low freq, many artifacts, many samples",UPN2_057,4,106155218,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu40Gln/c.119T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),25023,269,25382,"0,0105980616",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,4,Damaging,"31,42","19,83"
"low bq, low freq, many artifacts, many samples",UPN2_058,4,106155218,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu40Gln/c.119T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),36072,376,36563,"0,0102836201",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,4,Damaging,"31,48","17,98"
"low bq, low freq, many artifacts",UPN2_013,4,106155218,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu40Gln/c.119T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),10881,118,11033,"0,0106951872",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,4,Damaging,"32,03","18,79"
"low bq, low freq, many artifacts",UPN2_041,4,106155224,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu42Val/c.125A>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),5106,54,5236,"0,0103132162",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,77",Neutral,1,Damaging,"33,63","19,3"
"low freq, many artifacts",UPN2_044,4,106155246,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn49Lys/c.147T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),3834,39,3883,"0,0100437806",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,44",Neutral,0,Damaging,"35,59","34,77"
"low freq, many artifacts",UPN2_041,4,106155274,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser59Gly/c.175A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),4481,47,4534,"0,0103661226",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,"0,008",Damaging,"35,63","35,51"
"low freq, many artifacts",UPN2_056,4,106155274,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser59Gly/c.175A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),3371,44,3416,"0,0128805621",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,"0,008",Damaging,"35,6",36
"low freq, many artifacts",UPN2_041,4,106155301,G,C,missense_variant(MODERATE|MISSENSE|Gga/Cga|p.Gly68Arg/c.202G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),8601,90,8745,"0,0102915952",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,19",Deleterious,"0,06",Tolerated,"31,8","29,87"
"low freq, many artifacts",UPN2_034,4,106155308,A,G,missense_variant(MODERATE|MISSENSE|cAg/cGg|p.Gln70Arg/c.209A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),2953,30,2992,"0,010026738",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,"0,029",Damaging,"34,15","31,13"
"inspected, bad alignment",UPN2_042,4,106155328,GACTTTAC,G,frameshift_variant(HIGH||tttacacaa/|p.Phe78fs/c.232_238delTTTACAC|2002|TET2|protein_coding|CODING|ENST00000380013|3|G|INFO_REALIGN_3_PRIME),12188,382,12683,"0,030119057",0,0,0,1,1,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,24",NA
"many samples, low freq",UPN2_016,4,106155331,T,C,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe78Leu/c.232T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),4787,50,4870,"0,0102669405",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,"0,404",Tolerated,"33,94","33,72"
"many samples, low freq",UPN2_018,4,106155331,T,C,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe78Leu/c.232T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),6311,81,6434,"0,012589369",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,"0,404",Tolerated,"33,68","34,43"
"many samples, low freq",UPN2_020,4,106155331,T,C,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe78Leu/c.232T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),3113,39,3175,"0,0122834646",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,"0,404",Tolerated,"33,87","33,62"
"many samples, low freq",UPN2_041,4,106155331,T,C,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe78Leu/c.232T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),8604,107,8765,"0,012207644",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,"0,404",Tolerated,"33,27","32,8"
"many samples, low freq",UPN2_024,4,106155331,T,C,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe78Leu/c.232T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),3204,34,3255,"0,0104454685",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,"0,404",Tolerated,"33,77","33,65"
"many samples, low freq",UPN2_042,4,106155331,T,C,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe78Leu/c.232T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),12091,128,12303,"0,0104039665",0,0,0,0,0,1,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,"0,404",Tolerated,"33,4","33,62"
"many samples, low freq",UPN2_043,4,106155331,T,C,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe78Leu/c.232T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),6023,65,6129,"0,010605319",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,"0,404",Tolerated,"33,44","32,75"
"many samples, low freq",UPN2_030,4,106155331,T,C,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe78Leu/c.232T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),6969,80,7094,"0,0112771356",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,"0,404",Tolerated,"33,8","33,25"
"many samples, low freq",UPN2_047,4,106155331,T,C,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe78Leu/c.232T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),12012,134,12240,"0,0109477124",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,"0,404",Tolerated,"33,3","34,21"
"many samples, low freq",UPN2_050,4,106155331,T,C,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe78Leu/c.232T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),6165,63,6269,"0,0100494497",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,"0,404",Tolerated,"33,29","33,84"
"many samples, low freq",UPN2_051,4,106155331,T,C,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe78Leu/c.232T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),7355,81,7496,"0,0108057631",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,"0,404",Tolerated,"33,43","32,84"
"inspected, many artifacts",UPN2_055,4,106155331,T,C,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe78Leu/c.232T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),9164,100,9320,"0,0107296137",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,"0,404",Tolerated,"33,49","33,03"
"inspected, many artifacts",UPN2_056,4,106155331,T,C,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe78Leu/c.232T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),6287,72,6400,"0,01125",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,"0,404",Tolerated,"33,48","34,22"
"many samples, low freq",UPN2_057,4,106155331,T,C,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe78Leu/c.232T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),7631,93,7778,"0,0119568012",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,"0,404",Tolerated,"33,47","32,65"
"many samples, low freq",UPN2_058,4,106155331,T,C,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe78Leu/c.232T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),8236,85,8351,"0,0101784217",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,"0,404",Tolerated,"33,57","33,75"
"low freq, many artifacts",UPN2_040,4,106155331,T,C,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe78Leu/c.232T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),11604,120,11792,"0,0101763908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,404,Tolerated,"33,81","33,2"
"many samples, low freq",UPN2_091,4,106155331,T,C,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe78Leu/c.232T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),4963,53,5030,"0,0105367793",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,"0,404",Tolerated,"34,27","33,43"
"inspected, many artifacts",UPN2_050,4,106155338,A,G,missense_variant(MODERATE|MISSENSE|cAa/cGa|p.Gln80Arg/c.239A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),6167,65,6268,"0,010370134",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,"0,02",Damaging,"34,1","34,09"
"inspected, many artifacts",UPN2_041,4,106155343,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser82Gly/c.244A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),8584,137,8762,"0,0156356996",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-0,03",Neutral,1,Tolerated,"34,02","33,68"
"inspected, many artifacts",UPN2_056,4,106155347,G,T,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg83Ile/c.248G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),6312,78,6405,"0,0121779859",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,"0,001",Damaging,"33,94","32,53"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106155369,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln90His/c.270A>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),5972,62,6059,"0,0102327117",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,0,Damaging,"33,94","24,73"
"low bq, low freq, many artifacts, many samples",UPN2_053,4,106155369,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln90His/c.270A>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),4454,55,4527,"0,0121493263",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,0,Damaging,"34,17","19,69"
"Not in 2nd illumina, inspected, many artifacts",UPN2_006,4,106155374,G,T,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly92Val/c.275G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),5858,96,5957,"0,0161154944",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,4",Deleterious,0,Damaging,"34,7","33,08"
"low freq, many artifacts, many samples",UPN2_001,4,106155377,G,A,missense_variant(MODERATE|MISSENSE|gGa/gAa|p.Gly93Glu/c.278G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),1918,20,1954,"0,0102354145",0,0,0,0,1,0,0,0,1,NO,NO,COSM5479691. COSM5479692,Something is odd...,0,NO,NO,NO,NO,NO,NO,"-2,83",Deleterious,0,Damaging,"32,9",32
"many samples, strandbias",UPN2_030,4,106155377,G,A,missense_variant(MODERATE|MISSENSE|gGa/gAa|p.Gly93Glu/c.278G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),3513,44,3574,"0,012311136",0,0,0,0,1,0,0,1,2,NO,NO,"COSM5479691, COSM5479692",Something is odd...,0,NO,NO,NO,NO,NO,NO,"-2,83",Deleterious,0,Damaging,"33,82","32,55"
"inspected, strandbias, bad alignment",UPN2_035,4,106155377,G,A,missense_variant(MODERATE|MISSENSE|gGa/gAa|p.Gly93Glu/c.278G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),6576,91,6698,"0,0135861451",0,0,0,0,1,1,0,1,3,NO,NO,"COSM5479691, COSM5479692",Something is odd...,0,NO,NO,NO,NO,NO,NO,"-2,83",Deleterious,0,Damaging,"33,69","31,88"
"low freq, many artifacts",UPN2_049,4,106155377,G,A,missense_variant(MODERATE|MISSENSE|gGa/gAa|p.Gly93Glu/c.278G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),3919,44,3996,"0,011011011",0,0,0,0,1,0,0,0,1,NO,NO,COSM5479691. COSM5479692,Something is odd...,0,NO,NO,NO,NO,NO,NO,"-2,83",Deleterious,0,Damaging,"31,37","31,59"
"many samples, strandbias",UPN2_052,4,106155377,G,A,missense_variant(MODERATE|MISSENSE|gGa/gAa|p.Gly93Glu/c.278G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),2471,44,2542,"0,0173092054",0,0,0,0,1,1,0,1,3,NO,NO,"COSM5479691, COSM5479692",Something is odd...,0,NO,NO,NO,NO,NO,NO,"-2,83",Deleterious,0,Damaging,"31,75","32,36"
"many samples, strandbias",UPN2_008,4,106155377,G,A,missense_variant(MODERATE|MISSENSE|gGa/gAa|p.Gly93Glu/c.278G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),6220,73,6356,"0,0114852108",0,0,0,0,1,1,0,1,3,NO,NO,"COSM5479691, COSM5479692",Something is odd...,0,NO,NO,NO,NO,NO,NO,"-2,83",Deleterious,0,Damaging,"33,01","32,48"
"many samples, strandbias",UPN2_011,4,106155377,G,A,missense_variant(MODERATE|MISSENSE|gGa/gAa|p.Gly93Glu/c.278G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),5949,102,6090,"0,0167487685",0,0,0,0,1,1,0,0,2,NO,NO,"COSM5479691, COSM5479692",Something is odd...,0,NO,NO,NO,NO,NO,NO,"-2,83",Deleterious,0,Damaging,"33,15","31,94"
"many samples, strandbias",UPN2_057,4,106155377,G,A,missense_variant(MODERATE|MISSENSE|gGa/gAa|p.Gly93Glu/c.278G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),3834,64,3934,"0,0162684291",0,0,0,0,1,1,0,1,3,NO,NO,"COSM5479691, COSM5479692",Something is odd...,0,NO,NO,NO,NO,NO,NO,"-2,83",Deleterious,0,Damaging,"31,68","31,61"
"many samples, strandbias",UPN2_093,4,106155377,G,A,missense_variant(MODERATE|MISSENSE|gGa/gAa|p.Gly93Glu/c.278G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),2170,36,2219,"0,0162235241",0,0,0,0,1,1,0,1,3,NO,NO,"COSM5479691, COSM5479692",Something is odd...,0,NO,NO,NO,NO,NO,NO,"-2,83",Deleterious,0,Damaging,"33,03","32,44"
"many samples, strandbias",UPN2_107,4,106155377,G,A,missense_variant(MODERATE|MISSENSE|gGa/gAa|p.Gly93Glu/c.278G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),6972,72,7077,"0,0101738025",0,0,0,0,1,0,0,1,2,NO,NO,"COSM5479691, COSM5479692",Something is odd...,0,NO,NO,NO,NO,NO,NO,"-2,83",Deleterious,0,Damaging,"33,03","31,83"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106155377,G,T,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly93Val/c.278G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),3002,34,3068,"0,0110821382",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,0,Damaging,"31,85","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_052,4,106155377,G,T,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly93Val/c.278G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),2471,27,2542,"0,0106215578",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,0,Damaging,"31,75",14
"inspected, many artifacts",UPN2_044,4,106155389,C,T,missense_variant(MODERATE|MISSENSE|aCa/aTa|p.Thr97Ile/c.290C>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),5017,72,5093,"0,0141370509",0,0,0,0,1,1,0,1,3,NO,NO,"COSM1228964, COSM1228965",large_intestine,2,NO,NO,NO,NO,NO,NO,"-2,84",Deleterious,0,Damaging,"35,32","35,58"
"homo TC, many samples",UPN2_059,4,106155402,TTC,T,frameshift_variant(HIGH||tct/|p.Ser104fs/c.311_312delCT|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),53232,1012,54519,"0,0185623361",1,0,0,1,0,0,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,17",NA
"homo TC, many samples",UPN2_060,4,106155402,TTC,T,frameshift_variant(HIGH||tct/|p.Ser104fs/c.311_312delCT|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),34146,686,34990,"0,0196056016",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,11",NA
"homo TC, many samples",UPN2_091,4,106155402,TTC,T,frameshift_variant(HIGH||tct/|p.Ser104fs/c.311_312delCT|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),12944,136,13126,"0,0103611153",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,51",NA
"low freq, many artifacts, many samples",UPN2_092,4,106155402,TTC,T,frameshift_variant(HIGH||tct/|p.Ser104fs/c.311_312delCT|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),9335,108,9476,"0,011397214",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,52",NA
"homo TC, many samples",UPN2_061,4,106155402,TTC,T,frameshift_variant(HIGH||tct/|p.Ser104fs/c.311_312delCT|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),32498,635,33310,"0,0190633443",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,1",NA
"homo TC, many samples",UPN2_062,4,106155402,TTC,T,frameshift_variant(HIGH||tct/|p.Ser104fs/c.311_312delCT|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),28783,487,29415,"0,0165561788",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,09",NA
"homo TC, many samples",UPN2_063,4,106155402,TTC,T,frameshift_variant(HIGH||tct/|p.Ser104fs/c.311_312delCT|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),36222,577,36990,"0,0155988105",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,1",NA
"homo TC, many samples",UPN2_064,4,106155402,TTC,T,frameshift_variant(HIGH||tct/|p.Ser104fs/c.311_312delCT|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),45580,834,46635,"0,0178835638",1,0,0,1,0,0,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,08",NA
"homo TC, many samples",UPN2_065,4,106155402,TTC,T,frameshift_variant(HIGH||tct/|p.Ser104fs/c.311_312delCT|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),37684,669,38571,"0,0173446372",1,0,0,1,0,0,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,13",NA
"homo TC, many samples",UPN2_066,4,106155402,TTC,T,frameshift_variant(HIGH||tct/|p.Ser104fs/c.311_312delCT|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),56623,1049,57980,"0,0180924457",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,09",NA
"homo TC, many samples",UPN2_067,4,106155402,TTC,T,frameshift_variant(HIGH||tct/|p.Ser104fs/c.311_312delCT|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),62521,1072,63903,"0,0167754253",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,13",NA
"inspected, homo TC, many samples",UPN2_068,4,106155402,TTC,T,frameshift_variant(HIGH||tct/|p.Ser104fs/c.311_312delCT|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),40157,548,40909,"0,0133955853",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,08",NA
"homo TC, many samples",UPN2_069,4,106155402,TTC,T,frameshift_variant(HIGH||tct/|p.Ser104fs/c.311_312delCT|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),40820,607,41616,"0,0145857363",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,08",NA
"homo TC, many samples",UPN2_070,4,106155402,TTC,T,frameshift_variant(HIGH||tct/|p.Ser104fs/c.311_312delCT|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),27761,423,28331,"0,0149306413",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,04",NA
"homo TC, many samples",UPN2_071,4,106155402,TTC,T,frameshift_variant(HIGH||tct/|p.Ser104fs/c.311_312delCT|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),20935,397,21431,"0,0185245672",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,12",NA
"homo TC, many samples",UPN2_072,4,106155402,TTC,T,frameshift_variant(HIGH||tct/|p.Ser104fs/c.311_312delCT|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),31226,349,31734,"0,0109976681",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,05",NA
"homo TC, many samples",UPN2_073,4,106155402,TTC,T,frameshift_variant(HIGH||tct/|p.Ser104fs/c.311_312delCT|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),26342,417,26898,"0,0155030114",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,09",NA
"homo TC, many samples",UPN2_074,4,106155402,TTC,T,frameshift_variant(HIGH||tct/|p.Ser104fs/c.311_312delCT|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),28470,365,28964,"0,0126018506",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,11",NA
"homo TC, many samples",UPN2_075,4,106155402,TTC,T,frameshift_variant(HIGH||tct/|p.Ser104fs/c.311_312delCT|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),35850,614,36650,"0,0167530696",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,14",NA
"homo TC, many samples",UPN2_076,4,106155402,TTC,T,frameshift_variant(HIGH||tct/|p.Ser104fs/c.311_312delCT|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),33931,679,34781,"0,0195221529",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,15",NA
"homo TC, many samples",UPN2_077,4,106155402,TTC,T,frameshift_variant(HIGH||tct/|p.Ser104fs/c.311_312delCT|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),39997,596,40790,"0,0146114244",1,0,0,1,0,0,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,11",NA
"homo TC, many samples",UPN2_078,4,106155402,TTC,T,frameshift_variant(HIGH||tct/|p.Ser104fs/c.311_312delCT|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),30991,594,31762,"0,0187015931",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,15",NA
"homo TC, many samples",UPN2_079,4,106155402,TTC,T,frameshift_variant(HIGH||tct/|p.Ser104fs/c.311_312delCT|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),20383,359,20845,"0,0172223555",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,11",NA
"homo TC, many samples",UPN2_080,4,106155402,TTC,T,frameshift_variant(HIGH||tct/|p.Ser104fs/c.311_312delCT|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),33582,704,34432,"0,0204460967",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,09",NA
"homo TC, many samples",UPN2_081,4,106155402,TTC,T,frameshift_variant(HIGH||tct/|p.Ser104fs/c.311_312delCT|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),45558,681,46521,"0,0146385503",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,12",NA
"homo TC, many samples",UPN2_082,4,106155402,TTC,T,frameshift_variant(HIGH||tct/|p.Ser104fs/c.311_312delCT|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),54292,857,55419,"0,0154640105",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,09",NA
"homo TC, many samples",UPN2_083,4,106155402,TTC,T,frameshift_variant(HIGH||tct/|p.Ser104fs/c.311_312delCT|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),41783,704,42711,"0,0164828733",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,1",NA
"homo TC, many samples",UPN2_084,4,106155402,TTC,T,frameshift_variant(HIGH||tct/|p.Ser104fs/c.311_312delCT|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),51971,795,53046,"0,0149869924",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,13",NA
"homo TC, many samples",UPN2_085,4,106155402,TTC,T,frameshift_variant(HIGH||tct/|p.Ser104fs/c.311_312delCT|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),50092,790,51141,"0,0154474883",1,0,0,1,0,0,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,14",NA
"homo TC, many samples",UPN2_086,4,106155402,TTC,T,frameshift_variant(HIGH||tct/|p.Ser104fs/c.311_312delCT|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),40777,768,41777,"0,018383321",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,16",NA
"homo TC, many samples",UPN2_087,4,106155402,TTC,T,frameshift_variant(HIGH||tct/|p.Ser104fs/c.311_312delCT|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),49454,662,50373,"0,013141961",1,0,0,1,0,0,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,14",NA
"homo TC, many samples",UPN2_088,4,106155402,TTC,T,frameshift_variant(HIGH||tct/|p.Ser104fs/c.311_312delCT|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),36793,668,37642,"0,0177461346",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,12",NA
"inspected, many artifacts",UPN2_044,4,106155419,T,C,missense_variant(MODERATE|MISSENSE|cTt/cCt|p.Leu107Pro/c.320T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),5005,65,5093,"0,0127626154",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,41",Neutral,"0,028",Damaging,"34,73","35,14"
"low freq, many artifacts, many samples",UPN2_044,4,106155430,A,G,missense_variant(MODERATE|MISSENSE|Aaa/Gaa|p.Lys111Glu/c.331A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),5032,51,5090,"0,0100196464",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,4,Damaging,"35,19","34,47"
"inspected, many artifacts",UPN2_041,4,106155451,G,A,missense_variant(MODERATE|MISSENSE|Gct/Act|p.Ala118Thr/c.352G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),3861,42,3918,"0,010719755",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,"0,014",Damaging,"33,65","32,69"
"inspected, many artifacts",UPN2_044,4,106155484,C,T,stop_gained(HIGH|NONSENSE|Caa/Taa|p.Gln129*/c.385C>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),9037,116,9176,"0,0126416739",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,27","34,12"
"low freq, many artifacts, many samples",UPN2_044,4,106155503,A,T,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu135Val/c.404A>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),9039,92,9171,"0,0100316214",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,19",Neutral,45,Damaging,"34,37","31,4"
"low bq, low freq, many artifacts, many samples",UPN2_041,4,106155510,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser137Arg/c.411T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),7745,79,7869,"0,0100393951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,-1,Neutral,151,Tolerated,"32,14","25,77"
"inspected, many artifacts",UPN2_044,4,106155511,C,T,stop_gained(HIGH|NONSENSE|Caa/Taa|p.Gln138*/c.412C>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),9028,124,9169,"0,0135238303",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,67","32,69"
"low bq, low freq, many artifacts, many samples",UPN2_041,4,106155517,A,T,missense_variant(MODERATE|MISSENSE|Aat/Tat|p.Asn140Tyr/c.418A>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),7764,82,7862,"0,0104299161",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,15",Neutral,4,Damaging,"33,44","25,45"
"inspected, many artifacts",UPN2_041,4,106155560,T,C,missense_variant(MODERATE|MISSENSE|gTa/gCa|p.Val154Ala/c.461T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),4044,44,4098,"0,0107369449",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-0,34",Neutral,"0,478",Tolerated,"35,54","35,91"
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106155590,C,A,missense_variant(MODERATE|MISSENSE|aCc/aAc|p.Thr164Asn/c.491C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),53711,557,54454,"0,010228817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,49,Damaging,"31,25","15,73"
"inspected, bad alignment!",UPN2_048,4,106155653,A,G,missense_variant(MODERATE|MISSENSE|cAg/cGg|p.Gln185Arg/c.554A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),8011,84,8125,"0,0103384615",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,34",Neutral,0,Damaging,"33,39","30,71"
"inspected, bad alignment!",UPN2_043,4,106155664,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser189Gly/c.565A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),34054,366,34535,"0,0105979441",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,67",Neutral,"0,043",Damaging,"34,32","33,19"
"inspected, bad alignment!",UPN2_049,4,106155664,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser189Gly/c.565A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),32321,336,32755,"0,0102579759",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,67",Neutral,"0,043",Damaging,"34,3","32,89"
"low bq, low freq, many artifacts, many samples",UPN2_059,4,106155666,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser189Arg/c.567T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),33455,382,34007,"0,0112329814",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,84,Tolerated,"31,35","15,9"
"low bq, low freq, many artifacts, many samples",UPN2_061,4,106155666,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser189Arg/c.567T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),42209,531,42954,"0,0123620617",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,84,Tolerated,"31,24","15,97"
"low bq, low freq, many artifacts, many samples",UPN2_062,4,106155666,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser189Arg/c.567T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),37440,458,38122,"0,0120140601",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,84,Tolerated,"31,21","15,8"
"low bq, low freq, many artifacts, many samples",UPN2_063,4,106155666,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser189Arg/c.567T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),48001,571,48801,"0,0117005799",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,84,Tolerated,"31,3","15,62"
"low bq, low freq, many artifacts, many samples",UPN2_064,4,106155666,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser189Arg/c.567T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),36101,453,36763,"0,0123221717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,84,Tolerated,"31,23","16,14"
"low bq, low freq, many artifacts, many samples",UPN2_065,4,106155666,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser189Arg/c.567T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),33214,408,33785,"0,0120763653",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,84,Tolerated,"31,35","16,21"
"low bq, low freq, many artifacts, many samples",UPN2_066,4,106155666,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser189Arg/c.567T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),56269,683,57242,"0,0119317983",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,84,Tolerated,"31,37","16,11"
"low bq, low freq, many artifacts, many samples",UPN2_068,4,106155666,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser189Arg/c.567T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),44459,622,45290,"0,0137337161",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,84,Tolerated,"31,25","16,25"
"low bq, low freq, many artifacts, many samples",UPN2_069,4,106155666,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser189Arg/c.567T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),50781,638,51679,"0,0123454401",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,84,Tolerated,"31,39","16,04"
"low bq, low freq, many artifacts, many samples",UPN2_070,4,106155666,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser189Arg/c.567T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),34546,472,35230,"0,0133976724",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,84,Tolerated,"31,17","15,94"
"low bq, low freq, many artifacts, many samples",UPN2_071,4,106155666,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser189Arg/c.567T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),29916,348,30392,"0,0114503817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,84,Tolerated,"31,35","15,71"
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106155666,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser189Arg/c.567T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),39570,509,40278,"0,0126371717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,84,Tolerated,"31,27","16,04"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106155666,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser189Arg/c.567T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),29651,372,30201,"0,0123174729",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,84,Tolerated,"31,35","16,11"
"low bq, low freq, many artifacts, many samples",UPN2_074,4,106155666,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser189Arg/c.567T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),29109,333,29596,"0,0112515205",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,84,Tolerated,"31,38","15,56"
"low bq, low freq, many artifacts, many samples",UPN2_076,4,106155666,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser189Arg/c.567T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),44168,570,44963,"0,0126770901",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,84,Tolerated,"31,15","15,94"
"low bq, low freq, many artifacts, many samples",UPN2_077,4,106155666,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser189Arg/c.567T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),47500,581,48320,"0,0120240066",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,84,Tolerated,"31,27","16,05"
"low bq, low freq, many artifacts, many samples",UPN2_078,4,106155666,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser189Arg/c.567T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),45390,583,46197,"0,0126198671",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,84,Tolerated,"31,26","15,75"
"low bq, low freq, many artifacts, many samples",UPN2_079,4,106155666,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser189Arg/c.567T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),28431,358,28935,"0,0123725592",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,84,Tolerated,"31,29","16,3"
"low bq, low freq, many artifacts, many samples",UPN2_080,4,106155666,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser189Arg/c.567T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),45550,587,46386,"0,0126546803",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,84,Tolerated,"31,3","16,1"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106155666,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser189Arg/c.567T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),49206,612,50067,"0,0122236203",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,84,Tolerated,"31,28",16
"low bq, low freq, many artifacts, many samples",UPN2_082,4,106155666,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser189Arg/c.567T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),54291,606,55131,"0,0109920009",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,84,Tolerated,"31,31","16,11"
"low bq, low freq, many artifacts, many samples",UPN2_083,4,106155666,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser189Arg/c.567T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),55045,689,55993,"0,0123051096",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,84,Tolerated,"31,23","16,08"
"low bq, low freq, many artifacts, many samples",UPN2_084,4,106155666,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser189Arg/c.567T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),63599,789,64696,"0,0121954989",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,84,Tolerated,"31,15","15,93"
"low bq, low freq, many artifacts, many samples",UPN2_085,4,106155666,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser189Arg/c.567T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),44899,608,45741,"0,0132922324",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,84,Tolerated,"31,3","16,37"
"low bq, low freq, many artifacts, many samples",UPN2_086,4,106155666,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser189Arg/c.567T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),30931,431,31520,"0,0136738579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,84,Tolerated,"31,16","15,89"
"low bq, low freq, many artifacts, many samples",UPN2_087,4,106155666,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser189Arg/c.567T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),55923,704,56940,"0,0123638918",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,84,Tolerated,"31,27","15,95"
"low bq, low freq, many artifacts",UPN2_088,4,106155666,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser189Arg/c.567T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),46015,518,46834,"0,0110603408",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,84,Tolerated,"31,43","15,88"
"low freq, many samples, bad alignment",UPN2_001,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),21079,2401,23558,"0,1019186688",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,76","31,65"
"low freq, many samples, bad alignment",UPN2_014,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),26215,2158,28478,"0,0757777934",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,59","31,79"
"low freq, many samples, bad alignment",UPN2_015,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),34624,2432,37191,"0,0653921648",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,64","31,81"
"low freq, many samples, bad alignment",UPN2_016,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),17240,1313,18631,"0,0704739413",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,62","31,78"
"low freq, many samples, bad alignment",UPN2_017,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),12093,1051,13195,"0,0796513831",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,67","31,93"
"low freq, many samples, bad alignment",UPN2_018,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),18053,1453,19581,"0,0742045861",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,63","31,73"
"low freq, many samples, bad alignment",UPN2_019,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),20772,1690,22540,"0,0749778172",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,66","31,8"
"low freq, many samples, bad alignment",UPN2_020,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),16741,1335,18147,"0,0735658787",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,71","31,81"
"low freq, many samples, bad alignment",UPN2_021,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),18823,1711,20616,"0,0829937912",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,71","31,74"
"low freq, many samples, bad alignment",UPN2_002,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),27670,3244,31013,"0,1046012962",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,69","31,66"
"low freq, many samples, bad alignment",UPN2_003,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),5277,575,5871,"0,0979390223",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,76","31,64"
"low freq, many samples, bad alignment",UPN2_022,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),30056,2371,32547,"0,072848496",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,67","31,84"
"low freq, many samples, bad alignment",UPN2_023,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),30975,2560,33670,"0,076032076",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,62","31,65"
"low freq, many samples, bad alignment",UPN2_024,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),14462,917,15434,"0,0594142802",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,68","31,74"
"low freq, many samples, bad alignment",UPN2_025,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),31272,2561,33966,"0,0753989283",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,64","31,78"
"low freq, many samples, bad alignment",UPN2_026,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),33020,2676,35842,"0,0746610122",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,65","31,77"
"low freq, many samples, bad alignment",UPN2_004,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),4534,728,5273,"0,1380618244",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,08","31,77"
"low freq, many samples, bad alignment",UPN2_027,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),37789,3337,41267,"0,0808636441",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,7","31,82"
"low freq, many samples, bad alignment",UPN2_089,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),23808,713,24573,"0,0290155862",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,61","31,97"
"low freq, many samples, bad alignment",UPN2_042,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),27542,487,28226,"0,017253596",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"34,06","32,31"
"low freq, many samples, bad alignment",UPN2_028,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),27430,2197,29738,"0,0738785392",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,63","31,83"
"inspected, bad alignment, strandbias, many samples",UPN2_043,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),27911,1011,29103,"0,0347386867",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,47","31,76"
"low freq, many samples, bad alignment",UPN2_044,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),9224,406,9679,"0,0419464821",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,33","31,82"
"low freq, many samples, bad alignment",UPN2_029,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),31509,2489,34109,"0,0729719429",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,7","31,74"
"low freq, many samples, bad alignment",UPN2_030,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),28131,2191,30426,"0,0720107803",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,69","31,8"
"low freq, many samples, bad alignment",UPN2_031,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),18139,1375,19596,"0,0701673811",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,69","31,79"
"low freq, many samples, bad alignment",UPN2_005,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),8134,1071,9231,"0,1160220994",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,66","31,66"
"low freq, many samples, bad alignment",UPN2_045,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),35523,997,36704,"0,027163252",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,4","31,83"
"low freq, many samples, bad alignment",UPN2_032,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),11666,898,12606,"0,0712359194",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,58","31,7"
"low freq, many samples, bad alignment",UPN2_046,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),37026,1928,39184,"0,0492037566",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,37","31,72"
"low freq, many samples, bad alignment",UPN2_033,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),22461,1742,24294,"0,0717049477",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,61","31,82"
"low freq, many samples, bad alignment",UPN2_034,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),8553,590,9177,"0,0642911627",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,62","31,69"
"low freq, many samples, bad alignment",UPN2_047,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),28496,470,29192,"0,0161003015",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"34,15","32,4"
"low freq, many samples, bad alignment",UPN2_035,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),51355,3885,55492,"0,0700100915",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,69","31,76"
"low freq, many samples, bad alignment",UPN2_036,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),55998,4600,60828,"0,0756230683",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,63","31,84"
"low freq, many samples, bad alignment",UPN2_006,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),24711,2101,26903,"0,0780953797",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,99","31,84"
"inspected, bad alignment, strandbias, many samples",UPN2_049,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),20114,471,20740,"0,0227097396",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,91","31,82"
"low freq, many samples, bad alignment",UPN2_050,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),34609,911,35701,"0,0255174925",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,27","31,78"
"low freq, many samples, bad alignment",UPN2_037,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),35894,2641,38672,"0,0682923045",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,62","31,86"
"low freq, many samples, bad alignment",UPN2_051,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),29762,1157,31074,"0,0372337002",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,24","31,76"
"low freq, many samples, bad alignment",UPN2_052,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),31785,973,32913,"0,0295627867",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,21",32
"low freq, many samples, bad alignment",UPN2_038,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),49783,3860,53849,"0,0716819254",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,71","31,83"
"low freq, many samples, bad alignment",UPN2_039,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),45939,3841,49938,"0,0769153751",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,59","31,82"
"low freq, many samples, bad alignment",UPN2_053,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),42494,2163,44889,"0,0481855243",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,25","31,66"
"low freq, many samples, bad alignment",UPN2_054,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),28941,1110,30216,"0,0367355044",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,22","31,83"
"low freq, many samples, bad alignment",UPN2_007,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),64253,6550,71088,"0,0921393203",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,68","31,69"
"low freq, many samples, bad alignment",UPN2_008,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),78179,7548,86046,"0,0877205216",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,73","31,63"
"low freq, many samples, bad alignment",UPN2_009,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),63150,5328,68726,"0,0775252452",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,72","31,67"
"low freq, many samples, bad alignment",UPN2_010,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),49847,5081,55130,"0,0921639761",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,63","31,7"
"low freq, many samples, bad alignment",UPN2_011,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),59225,6625,66107,"0,100216316",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,6","31,65"
"low freq, many samples, bad alignment",UPN2_055,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),40512,1541,42288,"0,0364405978",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,42","31,74"
"low freq, many samples, bad alignment",UPN2_090,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),20002,545,20586,"0,0264743029",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,47","31,96"
"low freq, many samples, bad alignment",UPN2_057,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),43478,2191,45879,"0,047756054",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,24","31,72"
"low freq, many samples, bad alignment",UPN2_058,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),45008,2546,47829,"0,0532313032",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,28","31,68"
"low freq, many samples, bad alignment",UPN2_059,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),18116,298,18478,"0,0161272865",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"34,49","32,39"
"low freq, many samples, bad alignment",UPN2_012,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),29602,2848,32570,"0,0874424317",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,72","31,65"
"low freq, many samples, bad alignment",UPN2_060,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),41952,3974,46065,"0,0862694019",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,41","31,61"
"low freq, many samples, bad alignment",UPN2_040,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),65451,4929,70664,"0,0697526322",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,67","31,76"
"low freq, many samples, bad alignment",UPN2_013,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),16876,1680,18636,"0,0901481005",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,62","31,67"
"low freq, many samples, bad alignment",UPN2_091,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),16603,526,17157,"0,0306580404",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,8","31,81"
"low freq, many samples, bad alignment",UPN2_092,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),14809,450,15284,"0,0294425543",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,55","32,07"
"low freq, many samples, bad alignment",UPN2_093,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),16724,515,17276,"0,0298101412",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,52","31,81"
"low freq, many samples, bad alignment",UPN2_061,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),41128,4387,45670,"0,0960586818",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,28","31,64"
"low freq, many samples, bad alignment",UPN2_062,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),38577,4455,43162,"0,1032157917",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,2","31,61"
"low freq, many samples, bad alignment",UPN2_063,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),44370,4795,49335,"0,0971926624",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,35","31,53"
"low freq, many samples, bad alignment",UPN2_064,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),20624,602,21330,"0,0282231599",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"34,34","31,97"
"low freq, many samples, bad alignment",UPN2_065,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),22812,1150,24063,"0,0477912147",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,95","31,49"
"low freq, many samples, bad alignment",UPN2_066,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),56863,5592,62631,"0,0892848589",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,22","31,58"
"low freq, many samples, bad alignment",UPN2_067,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),64607,7360,72161,"0,101994152",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,08","31,54"
"inspected, bad alignment, strandbias, many samples",UPN2_068,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),46203,4860,51238,"0,0948514774",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,18","31,65"
"low freq, many samples, bad alignment",UPN2_069,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),51121,5003,56296,"0,0888695467",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,24","31,63"
"low freq, many samples, bad alignment",UPN2_070,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),34516,3639,38271,"0,0950850513",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,23","31,65"
"low freq, many samples, bad alignment",UPN2_071,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),28581,3070,31764,"0,0966502959",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,35","31,67"
"low freq, many samples, bad alignment",UPN2_072,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),32883,2930,35932,"0,0815429144",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,54","31,63"
"low freq, many samples, bad alignment",UPN2_073,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),20359,1142,21572,"0,052938995",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,92","31,59"
"low freq, many samples, bad alignment",UPN2_074,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),28986,3024,32107,"0,0941850687",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,19","31,53"
"low freq, many samples, bad alignment",UPN2_075,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),47996,4678,52845,"0,0885230391",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,33","31,61"
"low freq, many samples, bad alignment",UPN2_076,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),43947,4437,48542,"0,0914053809",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,22","31,57"
"low freq, many samples, bad alignment",UPN2_077,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),46996,4539,51711,"0,0877762952",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,24","31,63"
"low freq, many samples, bad alignment",UPN2_078,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),42679,4053,46890,"0,0864363404",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,36","31,62"
"low freq, many samples, bad alignment",UPN2_079,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),26172,2464,28743,"0,0857252201",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,37","31,56"
"low freq, many samples, bad alignment",UPN2_080,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),37709,3125,40947,"0,0763181674",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,53","31,65"
"low freq, many samples, bad alignment",UPN2_081,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),28344,659,29150,"0,0226072041",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"34,3","31,9"
"low freq, many samples, bad alignment",UPN2_082,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),52326,4438,56960,"0,0779143258",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,28","31,6"
"low freq, many samples, bad alignment",UPN2_083,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),52676,5642,58515,"0,0964197214",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,33","31,56"
"low freq, many samples, bad alignment",UPN2_084,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),61822,5612,67668,"0,0829343264",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,28","31,59"
"low freq, many samples, bad alignment",UPN2_085,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),49306,4836,54308,"0,0890476541",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,12","31,55"
"low freq, many samples, bad alignment",UPN2_086,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),37582,3958,41663,"0,09500036",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,33,"31,56"
"low freq, many samples, bad alignment",UPN2_087,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),53589,5029,58833,"0,0854792378",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,3","31,63"
"low freq, many samples, bad alignment",UPN2_088,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),44558,4726,49435,"0,0956002832",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,27","31,58"
"low freq, many samples, bad alignment",UPN2_094,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),20627,538,21197,"0,0253809501",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,59","31,92"
"low freq, many samples, bad alignment",UPN2_095,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),22785,701,23521,"0,0298031546",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,57","31,96"
"low freq, many samples, bad alignment",UPN2_096,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),22727,595,23354,"0,0254774343",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,63","31,87"
"low freq, many samples, bad alignment",UPN2_097,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),21013,655,21706,"0,0301759882",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,67","31,91"
"low freq, many samples, bad alignment",UPN2_098,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),19512,530,20089,"0,0263825974",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,85","32,04"
"low freq, many samples, bad alignment",UPN2_099,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),12376,385,12775,"0,0301369863",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,6","32,03"
"low freq, many samples, bad alignment",UPN2_100,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),19874,511,20418,"0,025026937",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,64","31,92"
"low freq, many samples, bad alignment",UPN2_101,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),21244,517,21806,"0,0237090709",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,54","31,77"
"low freq, many samples, bad alignment",UPN2_102,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),25363,706,26112,"0,0270373775",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,56","31,89"
"low freq, many samples, bad alignment",UPN2_103,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),22015,662,22721,"0,0291360415",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,56","31,63"
"low freq, many samples, bad alignment",UPN2_104,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),25562,807,26415,"0,0305508234",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,6","31,68"
"low freq, many samples, bad alignment",UPN2_105,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),20244,587,20864,"0,0281345859",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,65","31,77"
"low freq, many samples, bad alignment",UPN2_106,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),22442,369,22847,"0,016150917",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"34,15","32,17"
"low freq, many samples, bad alignment",UPN2_107,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),40626,1108,41824,"0,0264919663",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,62","31,73"
"low freq, many samples, bad alignment",UPN2_108,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),31645,736,32439,"0,0226887389",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,59","31,92"
"low freq, many samples, bad alignment",UPN2_109,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),34072,779,34924,"0,0223055778",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,59","31,93"
"low freq, many samples, bad alignment",UPN2_110,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),31356,552,31954,"0,0172748326",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,56","32,06"
"inspected, bad alignment, strandbias, many samples",UPN2_111,4,106155682,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys195Glu/c.583A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),30839,837,31733,"0,0263763275",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,21",Neutral,"0,163",Tolerated,"33,53","31,88"
"low freq, many artifacts",UPN2_004,4,106155699,TA,T,frameshift_variant(HIGH||aac/|p.Asn202fs/c.605delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),5216,81,5313,"0,0152456239",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,14",NA
"low freq, many artifacts",UPN2_048,4,106155716,T,A,missense_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu206Gln/c.617T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),3996,54,4065,"0,0132841328",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,"0,041",Damaging,"35,2","35,5"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106155757,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His220Asn/c.658C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),10152,111,10301,"0,0107756528",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,73",Neutral,1,Tolerated,"30,27","17,92"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106155757,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His220Asn/c.658C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),23683,256,23981,"0,0106751178",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,73",Neutral,1,Tolerated,"30,52","18,77"
"low bq, low freq, many artifacts, many samples",UPN2_045,4,106155757,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His220Asn/c.658C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),30824,317,31196,"0,0101615592",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,73",Neutral,1,Tolerated,"30,56","17,37"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106155757,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His220Asn/c.658C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),7713,80,7801,"0,0102550955",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,73",Neutral,1,Tolerated,"30,3","18,27"
"low bq, bad alignment, many samples",UPN2_048,4,106155757,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His220Asn/c.658C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),849,20,871,"0,0229621125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,73",Neutral,1,Tolerated,"23,75","18,35"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106155757,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His220Asn/c.658C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),9144,98,9249,"0,0105957401",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,73",Neutral,1,Tolerated,"30,36","17,89"
"low bq, low freq, many artifacts, many samples",UPN2_053,4,106155757,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His220Asn/c.658C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),41860,429,42366,"0,0101260445",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,73",Neutral,1,Tolerated,"30,54","17,94"
"low bq, low freq, many artifacts, many samples",UPN2_057,4,106155757,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His220Asn/c.658C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),43079,462,43612,"0,0105934147",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,73",Neutral,1,Tolerated,"30,51","18,33"
"low bq, low freq, many artifacts, many samples",UPN2_060,4,106155757,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His220Asn/c.658C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),43646,474,44161,"0,0107334526",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,73",Neutral,1,Tolerated,"30,73","18,28"
"low bq, low freq, many artifacts, many samples",UPN2_063,4,106155757,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His220Asn/c.658C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),49439,514,50029,"0,0102740411",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,73",Neutral,1,Tolerated,"30,74","17,87"
"low bq, low freq, many artifacts, many samples",UPN2_064,4,106155757,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His220Asn/c.658C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),5957,63,6021,"0,0104633782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,73",Neutral,1,Tolerated,"30,72","17,32"
"low bq, low freq, many artifacts, many samples",UPN2_065,4,106155757,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His220Asn/c.658C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),14198,171,14391,"0,0118824265",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,73",Neutral,1,Tolerated,"30,65","19,3"
"low bq, low freq, many artifacts, many samples",UPN2_066,4,106155757,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His220Asn/c.658C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),67384,717,68214,"0,0105110388",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,73",Neutral,1,Tolerated,"30,68","17,67"
"low bq, low freq, many artifacts, many samples",UPN2_067,4,106155757,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His220Asn/c.658C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),84947,891,85932,"0,0103686636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,73",Neutral,1,Tolerated,"30,71","17,56"
"low bq, low freq, many artifacts, many samples",UPN2_071,4,106155757,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His220Asn/c.658C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),32996,336,33356,"0,0100731503",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,73",Neutral,1,Tolerated,"30,74","17,48"
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106155757,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His220Asn/c.658C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),31393,321,31749,"0,0101105547",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,73",Neutral,1,Tolerated,"30,71","18,57"
"low bq, low freq, many artifacts, many samples",UPN2_074,4,106155757,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His220Asn/c.658C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),34163,359,34580,"0,0103817235",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,73",Neutral,1,Tolerated,"30,73","17,52"
"low bq, low freq, many artifacts, many samples",UPN2_075,4,106155757,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His220Asn/c.658C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),52657,589,53362,"0,0110378172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,73",Neutral,1,Tolerated,"30,77","17,25"
"low bq, low freq, many artifacts, many samples",UPN2_079,4,106155757,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His220Asn/c.658C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),28125,309,28470,"0,01085353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,73",Neutral,1,Tolerated,"30,73","18,01"
"low bq, low freq, many artifacts, many samples",UPN2_080,4,106155757,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His220Asn/c.658C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),35086,373,35528,"0,0104987615",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,73",Neutral,1,Tolerated,"30,82","18,47"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106155757,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His220Asn/c.658C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),8246,92,8350,"0,0110179641",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,73",Neutral,1,Tolerated,"30,77","16,46"
"low bq, low freq, many artifacts, many samples",UPN2_082,4,106155757,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His220Asn/c.658C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),58192,617,58899,"0,0104755599",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,73",Neutral,1,Tolerated,"30,68","17,41"
"low bq, low freq, many artifacts, many samples",UPN2_087,4,106155757,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His220Asn/c.658C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),60060,647,60801,"0,0106412723",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,73",Neutral,1,Tolerated,"30,76","17,73"
"low bq, low freq, many artifacts",UPN2_088,4,106155757,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His220Asn/c.658C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),51539,563,52196,"0,0107862671",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,73",Neutral,1,Tolerated,"30,76","18,11"
"low freq, many artifacts",UPN2_044,4,106155763,C,T,missense_variant(MODERATE|MISSENSE|Cat/Tat|p.His222Tyr/c.664C>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),8586,167,8769,"0,0190443608",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,"0,004",Damaging,"33,79","33,21"
"low freq, many artifacts",UPN2_047,4,106155778,GA,G,frameshift_variant(HIGH||aca/|p.Thr229fs/c.685delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|G|INFO_REALIGN_3_PRIME),7715,89,7850,"0,0113375796",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,78",NA
"low freq, many artifacts",UPN2_042,4,106155784,A,G,missense_variant(MODERATE|MISSENSE|Aca/Gca|p.Thr229Ala/c.685A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),10271,127,10475,"0,012124105",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,"0,106",Tolerated,"32,91","34,13"
inspected,UPN2_056,4,106155784,A,G,missense_variant(MODERATE|MISSENSE|Aca/Gca|p.Thr229Ala/c.685A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),925,127,1062,"0,1195856874",1,1,0,1,1,1,0,1,6,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,"0,106",Tolerated,"32,85","33,87"
"low freq, many artifacts",UPN2_064,4,106155784,A,G,missense_variant(MODERATE|MISSENSE|Aca/Gca|p.Thr229Ala/c.685A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),6017,73,6116,"0,0119359058",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,"0,106",Tolerated,"32,47","31,88"
"low freq, many artifacts",UPN2_004,4,106155811,G,A,missense_variant(MODERATE|MISSENSE|Gtt/Att|p.Val238Ile/c.712G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),6641,73,6723,"0,0108582478",0,0,0,0,1,0,0,1,2,NO,NO,"COSM4635066, COSM4635067",large_intestine,2,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,0,Damaging,"34,49","34,81"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106155832,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr245Pro/c.733A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),10257,105,10427,"0,0100700105",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,68",Neutral,2,Damaging,"30,53","24,61"
"low bq, low freq, many artifacts",UPN2_051,4,106155832,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr245Pro/c.733A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),29117,307,29596,"0,0103730234",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,68",Neutral,"0,002",Damaging,"30,64","25,76"
"low bq, low freq, many artifacts, many samples",UPN2_059,4,106155832,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr245Pro/c.733A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),2893,58,2967,"0,0195483654",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,68",Neutral,2,Damaging,"29,7","20,36"
"low bq, low freq, many artifacts, many samples",UPN2_060,4,106155832,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr245Pro/c.733A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),43102,843,44097,"0,0191169467",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,68",Neutral,2,Damaging,"29,55","19,48"
"low bq, low freq, many artifacts, many samples",UPN2_061,4,106155832,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr245Pro/c.733A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),47333,901,48447,"0,0185976428",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,68",Neutral,2,Damaging,"29,56","18,89"
"low bq, low freq, many artifacts, many samples",UPN2_062,4,106155832,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr245Pro/c.733A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),47291,897,48352,"0,018551456",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,68",Neutral,2,Damaging,"29,44","19,13"
"low bq, low freq, many artifacts, many samples",UPN2_063,4,106155832,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr245Pro/c.733A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),48898,913,50018,"0,0182534288",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,68",Neutral,2,Damaging,"29,57","18,7"
"low bq, low freq, many artifacts, many samples",UPN2_064,4,106155832,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr245Pro/c.733A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),5940,122,6076,"0,0200789993",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,68",Neutral,2,Damaging,"29,83","17,87"
"low bq, low freq, many artifacts, many samples",UPN2_065,4,106155832,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr245Pro/c.733A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),14140,240,14434,"0,0166274075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,68",Neutral,2,Damaging,"29,66","19,24"
"low bq, low freq, many artifacts, many samples",UPN2_066,4,106155832,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr245Pro/c.733A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),66787,1220,68239,"0,0178783394",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,68",Neutral,2,Damaging,"29,58","18,81"
"low bq, low freq, many artifacts, many samples",UPN2_067,4,106155832,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr245Pro/c.733A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),84166,1500,85983,"0,017445309",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,68",Neutral,2,Damaging,"29,67","19,12"
"low bq, low freq, many artifacts, many samples",UPN2_068,4,106155832,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr245Pro/c.733A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),56130,1047,57374,"0,0182486841",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,68",Neutral,2,Damaging,"29,58","19,12"
"low bq, low freq, many artifacts, many samples",UPN2_069,4,106155832,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr245Pro/c.733A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),59964,1019,61229,"0,0166424407",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,68",Neutral,2,Damaging,"29,64","18,9"
"low bq, low freq, many artifacts, many samples",UPN2_070,4,106155832,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr245Pro/c.733A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),40610,751,41523,"0,0180863618",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,68",Neutral,2,Damaging,"29,48","18,56"
"low bq, low freq, many artifacts, many samples",UPN2_071,4,106155832,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr245Pro/c.733A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),32684,562,33381,"0,0168359246",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,68",Neutral,2,Damaging,"29,71","18,7"
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106155832,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr245Pro/c.733A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),31016,613,31759,"0,0193016153",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,68",Neutral,2,Damaging,"29,54","20,06"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106155832,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr245Pro/c.733A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),12823,205,13083,"0,015669189",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,68",Neutral,2,Damaging,"29,67","19,41"
"low bq, low freq, many artifacts, many samples",UPN2_074,4,106155832,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr245Pro/c.733A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),33860,636,34628,"0,0183666397",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,68",Neutral,2,Damaging,"29,53","19,11"
"low bq, low freq, many artifacts, many samples",UPN2_075,4,106155832,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr245Pro/c.733A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),52103,995,53329,"0,0186577659",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,68",Neutral,2,Damaging,"29,67","19,5"
"low bq, low freq, many artifacts, many samples",UPN2_076,4,106155832,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr245Pro/c.733A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),51000,941,52155,"0,0180423737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,68",Neutral,2,Damaging,"29,5","18,54"
"low bq, low freq, many artifacts, many samples",UPN2_077,4,106155832,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr245Pro/c.733A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),54042,983,55264,"0,017787348",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,68",Neutral,2,Damaging,"29,6","18,9"
"low bq, low freq, many artifacts, many samples",UPN2_078,4,106155832,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr245Pro/c.733A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),46504,870,47594,"0,0182796151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,68",Neutral,2,Damaging,"29,43","19,22"
"low bq, low freq, many artifacts, many samples",UPN2_079,4,106155832,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr245Pro/c.733A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),27915,467,28463,"0,0164072656",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,68",Neutral,2,Damaging,"29,65","18,13"
"low bq, low freq, many artifacts, many samples",UPN2_080,4,106155832,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr245Pro/c.733A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),34749,630,35528,"0,0177324927",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,68",Neutral,2,Damaging,"29,68","19,19"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106155832,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr245Pro/c.733A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),8245,139,8415,"0,0165181224",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,68",Neutral,2,Damaging,"29,71","19,17"
"low bq, low freq, many artifacts, many samples",UPN2_082,4,106155832,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr245Pro/c.733A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),57742,1005,58958,"0,0170460328",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,68",Neutral,2,Damaging,"29,62","19,54"
"low bq, low freq, many artifacts, many samples",UPN2_083,4,106155832,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr245Pro/c.733A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),59832,1134,61204,"0,0185282008",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,68",Neutral,2,Damaging,"29,55","19,05"
"low bq, low freq, many artifacts, many samples",UPN2_084,4,106155832,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr245Pro/c.733A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),69237,1221,70757,"0,0172562432",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,68",Neutral,2,Damaging,"29,56","19,01"
"low bq, low freq, many artifacts, many samples",UPN2_085,4,106155832,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr245Pro/c.733A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),61638,1151,63021,"0,0182637534",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,68",Neutral,2,Damaging,"29,74","19,6"
"low bq, low freq, many artifacts, many samples",UPN2_086,4,106155832,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr245Pro/c.733A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),50677,965,51845,"0,0186131739",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,68",Neutral,2,Damaging,"29,54",19
"low bq, low freq, many artifacts, many samples",UPN2_087,4,106155832,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr245Pro/c.733A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),59546,1011,60797,"0,01662911",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,68",Neutral,2,Damaging,"29,68","19,15"
"low bq, low freq, many artifacts",UPN2_088,4,106155832,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr245Pro/c.733A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),51048,958,52221,"0,0183451102",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,68",Neutral,2,Damaging,"29,65","19,21"
"low freq, many artifacts",UPN2_081,4,106155847,A,T,missense_variant(MODERATE|MISSENSE|Aat/Tat|p.Asn250Tyr/c.748A>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),4303,46,4359,"0,0105528791",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,"0,001",Damaging,"35,42","31,57"
"low freq, many artifacts",UPN2_048,4,106155872,A,G,missense_variant(MODERATE|MISSENSE|aAt/aGt|p.Asn258Ser/c.773A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),3400,36,3443,"0,0104559977",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,"0,127",Tolerated,"35,55","35,28"
"low bq, low freq, many artifacts",UPN2_056,4,106155922,A,T,missense_variant(MODERATE|MISSENSE|Aat/Tat|p.Asn275Tyr/c.823A>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),7794,82,7907,"0,0103705577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,9",Neutral,3,Damaging,"31,55","26,84"
"low freq, many artifacts",UPN2_044,4,106155950,TG,T,frameshift_variant(HIGH||ctg/|p.Pro285fs/c.852delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),9751,119,9920,"0,0119959677",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,99",NA
"low freq, many artifacts",UPN2_048,4,106155994,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp299Tyr/c.895G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),5014,80,5103,"0,0156770527",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,"0,004",Damaging,"33,27","33,53"
"strandbias, many samples",UPN2_001,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),18641,2108,20797,"0,1013607732",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,85","31,54"
"strandbias, many samples",UPN2_014,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),24112,1785,25963,"0,0687516851",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,76","31,6"
"strandbias, many samples",UPN2_015,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),31361,1927,33390,"0,0577118898",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,75","31,63"
"strandbias, many samples",UPN2_016,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),15810,1205,17066,"0,0706082269",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,76","31,6"
"strandbias, many samples",UPN2_017,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),11216,846,12103,"0,0699000248",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,78","31,76"
"strandbias, many samples",UPN2_018,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),16867,1240,18166,"0,0682593857",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,82","31,7"
"strandbias, many samples",UPN2_019,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),18795,1401,20265,"0,0691339748",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,72","31,71"
"strandbias, many samples",UPN2_020,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),15511,1155,16728,"0,069045911",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,74","31,76"
"strandbias, many samples",UPN2_021,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),16636,1342,18016,"0,0744893428",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,79","31,64"
"strandbias, many samples",UPN2_002,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),25076,2880,28013,"0,1028094099",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,88","31,52"
"strandbias, many samples",UPN2_003,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),4614,475,5105,"0,0930460333",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,96","31,68"
"strandbias, many samples",UPN2_022,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),26180,1953,28207,"0,0692381324",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,78","31,7"
"strandbias, many samples",UPN2_023,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),28343,1906,30338,"0,0628254994",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,76","31,62"
"strandbias, many samples",UPN2_024,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),13253,767,14059,"0,0545558006",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,74","31,83"
"strandbias, many samples",UPN2_025,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),27849,2137,30070,"0,0710675091",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,8","31,69"
"strandbias, many samples",UPN2_026,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),28678,2152,30906,"0,0696304925",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,8","31,73"
"strandbias, many samples",UPN2_004,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),3528,420,3957,"0,1061410159",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,58","31,73"
"strandbias, many samples",UPN2_027,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),31509,2693,34307,"0,0784970997",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,81","31,62"
"strandbias, many samples",UPN2_089,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),21675,672,22398,"0,0300026788",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,75","31,65"
"inspected, strandbias, many samples",UPN2_042,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),26328,599,27045,"0,0221482714",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"34,21","31,57"
"strandbias, many samples",UPN2_028,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),23221,1704,24986,"0,068198191",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,85","31,65"
"strandbias, many samples",UPN2_043,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),26653,979,27751,"0,035278008",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,71","31,43"
"strandbias, many samples",UPN2_044,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),7833,297,8153,"0,0364283086",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,82","31,59"
"strandbias, many samples",UPN2_029,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),27598,1905,29583,"0,0643950918",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,85","31,72"
"strandbias, many samples",UPN2_030,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),24767,1940,26784,"0,0724313023",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,81","31,68"
"strandbias, many samples",UPN2_031,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),16483,1094,17636,"0,0620322068",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,8","31,75"
"strandbias, many samples",UPN2_005,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),6845,821,7678,"0,1069288877",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,83","31,66"
"strandbias, many samples",UPN2_045,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),34012,921,35054,"0,0262737491",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,63","31,49"
"strandbias, many samples",UPN2_032,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),10404,732,11172,"0,0655209452",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,73","31,66"
"strandbias, many samples",UPN2_046,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),31676,1371,33139,"0,0413711941",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,72","31,4"
"strandbias, many samples",UPN2_033,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),19955,1402,21424,"0,0654406273",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,74","31,75"
"strandbias, many samples",UPN2_034,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),7672,431,8130,"0,0530135301",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,82","31,86"
"strandbias, many samples",UPN2_047,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),27315,609,28032,"0,0217251712",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"34,33","31,77"
"strandbias, many samples",UPN2_035,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),43298,3158,46581,"0,0677958824",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,84","31,71"
"strandbias, many samples",UPN2_036,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),48044,3348,51550,"0,0649466537",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,89","31,71"
"strandbias, many samples",UPN2_006,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),22493,1925,24465,"0,078683834",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"34,12","31,57"
"strandbias, many samples",UPN2_049,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),18440,473,18969,"0,0249354209",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"34,15","31,96"
"strandbias, many samples",UPN2_050,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),30843,790,31779,"0,0248591837",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,63","31,69"
"strandbias, many samples",UPN2_037,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),32756,2320,35157,"0,0659897033",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,79","31,74"
"strandbias, many samples",UPN2_051,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),26827,880,27811,"0,031642156",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,62","31,56"
"strandbias, many samples",UPN2_052,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),28229,733,29046,"0,0252358328",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,61","31,49"
"strandbias, many samples",UPN2_038,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),42607,3365,46139,"0,0729317931",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,8","31,63"
"strandbias, many samples",UPN2_039,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),39839,2957,42936,"0,068869946",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,88","31,72"
"strandbias, many samples",UPN2_053,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),38264,1687,40112,"0,0420572397",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,64","31,53"
"strandbias, many samples",UPN2_054,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),25738,808,26673,"0,0302928055",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,65","31,53"
"strandbias, many samples",UPN2_007,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),54519,5711,60396,"0,0945592423",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,85","31,58"
"strandbias, many samples",UPN2_008,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),69116,7168,76531,"0,0936613921",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,85","31,55"
"strandbias, many samples",UPN2_009,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),56636,5505,62324,"0,0883287337",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,78","31,58"
"strandbias, many samples",UPN2_010,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),41586,4131,45858,"0,0900824284",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,9","31,61"
"strandbias, many samples",UPN2_011,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),50768,5014,55963,"0,0895949109",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,92","31,55"
"strandbias, many samples",UPN2_055,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),36434,1321,37895,"0,0348594801",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,72","31,6"
"low freq, many artifacts",UPN2_056,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),4387,45,4461,"0,0100874243",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,8,Damaging,"34,59","32,27"
"strandbias, many samples",UPN2_090,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),16722,359,17125,"0,0209635036",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,72","31,81"
"strandbias, many samples",UPN2_057,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),35483,1598,37246,"0,042903936",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,54","31,63"
"strandbias, many samples",UPN2_058,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),36651,2266,39018,"0,0580757599",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,52","31,49"
"strandbias, many samples",UPN2_059,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),15059,405,15501,"0,0261273466",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"34,67","31,58"
"strandbias, many samples",UPN2_012,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),25272,2545,27896,"0,0912317178",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,89","31,45"
"strandbias, many samples",UPN2_060,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),33450,2379,35918,"0,0662342001",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,88","31,51"
"strandbias, many samples",UPN2_040,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),57839,4132,62179,"0,0664533042",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,89","31,69"
"strandbias, many samples",UPN2_013,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),15042,1401,16499,"0,0849142372",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,92","31,66"
"strandbias, many samples",UPN2_091,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),15488,463,15978,"0,0289773438",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,72","31,89"
"strandbias, many samples",UPN2_092,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),11986,326,12325,"0,0264503043",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,78","31,74"
"strandbias, many samples",UPN2_093,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),13524,356,13899,"0,0256133535",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,73","31,83"
"strandbias, many samples",UPN2_061,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),30771,2549,33402,"0,0763127956",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,68","31,51"
"strandbias, many samples",UPN2_062,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),27947,2383,30406,"0,0783726896",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,76","31,47"
"strandbias, many samples",UPN2_063,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),31586,2543,34227,"0,0742980688",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,78","31,48"
"strandbias, many samples",UPN2_064,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),15837,603,16475,"0,0366009105",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"34,55","31,73"
"strandbias, many samples",UPN2_065,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),19896,1155,21114,"0,0547030406",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,97","31,47"
"strandbias, many samples",UPN2_066,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),42276,3868,46250,"0,0836324324",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,32","31,44"
"strandbias, many samples",UPN2_067,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),47601,4718,52468,"0,0899214759",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,37","31,52"
"strandbias, many samples",UPN2_068,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),34338,2999,37415,"0,080155018",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,46","31,51"
"strandbias, many samples",UPN2_069,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),37837,3110,41048,"0,0757649581",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,59","31,58"
"strandbias, many samples",UPN2_070,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),25439,1923,27459,"0,0700316836",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,66","31,49"
"strandbias, many samples",UPN2_071,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),22504,1588,24165,"0,0657148769",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,96","31,47"
"strandbias, many samples",UPN2_072,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),23731,1497,25279,"0,0592191147",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"34,03","31,6"
"strandbias, many samples",UPN2_073,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),17137,1000,18185,"0,0549903767",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"34,14","31,46"
"strandbias, many samples",UPN2_074,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),22159,2131,24363,"0,0874687025",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,47","31,56"
"strandbias, many samples",UPN2_075,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),36860,2958,39909,"0,0741186199",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,74","31,41"
"strandbias, many samples",UPN2_076,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),31920,2732,34753,"0,0786119184",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,67","31,56"
"strandbias, many samples",UPN2_077,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),35887,3177,39187,"0,0810728048",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,53","31,64"
"strandbias, many samples",UPN2_078,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),30780,2377,33245,"0,0714994736",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,71","31,55"
"strandbias, many samples",UPN2_079,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),19527,1625,21208,"0,0766220294",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,6","31,68"
"strandbias, many samples",UPN2_080,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),28449,1907,30465,"0,0625964221",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"34,04","31,45"
"strandbias, many samples",UPN2_081,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),25110,874,26063,"0,0335341288",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"34,45","31,54"
"strandbias, many samples",UPN2_082,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),42407,3283,45830,"0,0716343007",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,55","31,53"
"strandbias, many samples",UPN2_083,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),38850,3420,42370,"0,0807174888",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,63","31,55"
"strandbias, many samples",UPN2_084,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),44976,3747,48826,"0,0767418998",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,63","31,43"
"strandbias, many samples",UPN2_085,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),35658,3021,38771,"0,0779190632",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,47","31,45"
"strandbias, many samples",UPN2_086,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),24994,2257,27315,"0,0826285923",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,36","31,55"
"strandbias, many samples",UPN2_087,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),44011,3882,48015,"0,0808497345",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,54","31,48"
"strandbias, many samples",UPN2_088,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),32871,2979,35930,"0,0829112163",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,58","31,47"
"strandbias, many samples",UPN2_094,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),20996,489,21516,"0,0227272727",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,77","31,72"
"strandbias, many samples",UPN2_095,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),20774,634,21443,"0,0295667584",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,69","31,69"
"strandbias, many samples",UPN2_096,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),21940,566,22549,"0,0251008914",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,72","31,81"
"strandbias, many samples",UPN2_097,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),20360,613,21021,"0,0291613149",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,69","31,56"
"strandbias, many samples",UPN2_098,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),18432,467,18924,"0,024677658",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,92","31,77"
"strandbias, many samples",UPN2_099,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),11389,352,11760,"0,0299319728",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,69","31,61"
"strandbias, many samples",UPN2_100,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),19085,470,19593,"0,023988159",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,72","31,8"
"strandbias, many samples",UPN2_101,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),18915,414,19366,"0,0213776722",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,7","31,72"
"strandbias, many samples",UPN2_102,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),22304,585,22935,"0,0255068672",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,7","31,68"
"strandbias, many samples",UPN2_103,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),20168,582,20796,"0,0279861512",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,78","31,63"
"strandbias, many samples",UPN2_104,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),24466,736,25251,"0,0291473605",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,7","31,8"
"strandbias, many samples",UPN2_105,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),19027,546,19622,"0,0278259097",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,75","31,73"
"strandbias, many samples",UPN2_106,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),23637,381,24057,"0,0158373862",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"34,12","31,53"
"strandbias, many samples",UPN2_107,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),38497,1020,39586,"0,0257666852",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,75","31,74"
"strandbias, many samples",UPN2_108,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),29650,624,30328,"0,0205750462",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,82","31,72"
"strandbias, many samples",UPN2_109,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),31234,759,32052,"0,0236802696",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,68","31,87"
"strandbias, many samples",UPN2_110,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),31364,586,32014,"0,0183044918",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,73","31,76"
"strandbias, many samples",UPN2_111,4,106156012,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser305Gly/c.913A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),27747,718,28523,"0,0251726677",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,008",Damaging,"33,75","31,71"
"low freq, many artifacts",UPN2_048,4,106156047,T,A,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe316Leu/c.948T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),2537,40,2584,"0,0154798762",0,0,0,0,1,0,0,1,2,NO,NO,"COSM4625209, COSM4625208",large_intestine,2,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,"0,665",Tolerated,"35,32","34,25"
"low freq, many artifacts",UPN2_056,4,106156049,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln317Leu/c.950A>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),4394,47,4462,"0,0105333931",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,1,Damaging,"35,21","31,85"
"low freq, many artifacts",UPN2_044,4,106156094,G,A,missense_variant(MODERATE|MISSENSE|tGc/tAc|p.Cys332Tyr/c.995G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),6397,112,6528,"0,0171568627",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,"0,115",Tolerated,"31,59","32,96"
"low bq, low freq, many artifacts",UPN2_044,4,106156156,T,A,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys353Ser/c.1057T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),6406,77,6495,"0,0118552733",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,88",Neutral,"0,657",Tolerated,"33,2","27,78"
"low bq, low freq, many artifacts, many samples",UPN2_062,4,106156162,G,C,missense_variant(MODERATE|MISSENSE|Ggt/Cgt|p.Gly355Arg/c.1063G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),26845,288,27425,"0,0105013674",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,5,Damaging,"30,05","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_079,4,106156162,G,C,missense_variant(MODERATE|MISSENSE|Ggt/Cgt|p.Gly355Arg/c.1063G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),19568,233,20004,"0,0116476705",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,5,Damaging,"30,01","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_023,4,106156162,G,T,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly355Cys/c.1063G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),29190,357,29836,"0,0119654109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,93",Deleterious,7,Damaging,"29,1","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_045,4,106156162,G,T,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly355Cys/c.1063G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),31446,391,32104,"0,0121791677",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,93",Deleterious,7,Damaging,"30,85","14,46"
"low bq, low freq, many artifacts",UPN2_040,4,106156162,G,T,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly355Cys/c.1063G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),56600,697,57845,"0,0120494425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,93",Deleterious,7,Damaging,"28,95","14,23"
low freq!,UPN2_097,4,106156163,G,A,missense_variant(MODERATE|MISSENSE|gGt/gAt|p.Gly355Asp/c.1064G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),10805,301,11118,"0,0270732146",0,0,0,1,1,1,0,1,4,"4,3721",NO,NO,NO,O,rs61744960,rs61744960,NO,"0,027",NO,YES,"-2,2",Neutral,"0,005",Damaging,"35,13","35,54"
low bq,UPN2_041,4,106156176,T,G,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn359Lys/c.1077T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),886,26,915,"0,0284153005",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,119,Tolerated,"27,19","14,69"
"inspected, low freq, neutral effect",UPN2_048,4,106156178,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu360Ser/c.1079T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),3182,73,3262,"0,0223789086",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,32",Neutral,76,Tolerated,"31,75",32
"low freq, many artifacts",UPN2_049,4,106156178,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu360Ser/c.1079T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),13812,147,14011,"0,0104917565",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,32",Neutral,"0,076",Tolerated,"33,34","32,7"
"low freq, many artifacts",UPN2_048,4,106156183,G,A,missense_variant(MODERATE|MISSENSE|Gct/Act|p.Ala362Thr/c.1084G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),3231,34,3266,"0,0104102878",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,1",Tolerated,"35,46","33,47"
low freq!,UPN2_094,4,106156187,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro363Leu/c.1088C>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),17309,346,17661,"0,0195911896",0,0,0,0,1,1,0,0,2,"5,8953",NO,"COSM5020142, COSM5020141",soft_tissue,4,rs17253672,rs17253672,NO,"0,048",NO,YES,"-2,11",Neutral,"0,004",Damaging,"35,49","35,83"
low freq!,UPN2_097,4,106156187,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro363Leu/c.1088C>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),17230,420,17663,"0,0237785201",0,0,0,0,1,1,0,0,2,"5,8953",NO,"COSM5020142, COSM5020141",soft_tissue,4,rs17253672,rs17253672,NO,"0,048",NO,YES,"-2,11",Neutral,"0,004",Damaging,"35,48","35,82"
"low freq, many artifacts",UPN2_048,4,106156222,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu375*/c.1123G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),3222,37,3265,"0,0113323124",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,1","34,22"
"low freq, many artifacts",UPN2_044,4,106156230,T,TG,frameshift_variant(HIGH||ggt/ggGt|p.Ala379fs/c.1133dupG|2002|TET2|protein_coding|CODING|ENST00000380013|3|TG|INFO_REALIGN_3_PRIME),4428,48,4464,"0,0107526882",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,6",NA
"inspected, many artifacts",UPN2_041,4,106156249,A,T,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser384Cys/c.1150A>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),893,26,923,"0,0281690141",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,"0,042",Damaging,"30,99","32,27"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_015,4,106156252,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser385Thr/c.1153T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),19535,229,20104,"0,011390768",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,0,Damaging,"26,56","15,87"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_016,4,106156252,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser385Thr/c.1153T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),9388,97,9606,"0,0100978555",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,0,Damaging,"26,81","16,09"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_017,4,106156252,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser385Thr/c.1153T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),7323,98,7542,"0,0129939008",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,0,Damaging,"26,71","16,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_018,4,106156252,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser385Thr/c.1153T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),11053,142,11348,"0,0125132182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,0,Damaging,"26,64","15,36"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_019,4,106156252,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser385Thr/c.1153T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),12470,146,12816,"0,01139201",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,0,Damaging,"26,51","16,21"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_020,4,106156252,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser385Thr/c.1153T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),9645,116,9900,"0,0117171717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,0,Damaging,"26,71","16,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_022,4,106156252,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser385Thr/c.1153T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),16768,183,17211,"0,0106327349",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,0,Damaging,"26,68","15,15"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_023,4,106156252,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser385Thr/c.1153T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),17911,211,18451,"0,0114356945",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,0,Damaging,"26,7","16,13"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_024,4,106156252,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser385Thr/c.1153T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),8214,109,8444,"0,0129085741",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,0,Damaging,"26,74","18,35"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_025,4,106156252,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser385Thr/c.1153T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),18190,187,18651,"0,010026272",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,0,Damaging,"26,7","16,53"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_026,4,106156252,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser385Thr/c.1153T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),19343,245,19911,"0,0123047562",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,0,Damaging,"26,76","15,91"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_027,4,106156252,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser385Thr/c.1153T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),21309,259,21949,"0,011800082",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,0,Damaging,"26,58","15,63"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,4,106156252,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser385Thr/c.1153T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),25576,355,26548,"0,0133720054",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,0,Damaging,"26,96","15,37"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_028,4,106156252,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser385Thr/c.1153T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),15136,208,15622,"0,0133145564",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,0,Damaging,"26,66","15,75"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106156252,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser385Thr/c.1153T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),18397,256,19028,"0,0134538575",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,0,Damaging,"27,12","15,77"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_044,4,106156252,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser385Thr/c.1153T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),2231,37,2320,"0,0159482759",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,0,Damaging,"26,96","16,16"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_029,4,106156252,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser385Thr/c.1153T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),17514,198,17996,"0,011002445",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,0,Damaging,"26,73","16,92"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_030,4,106156252,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser385Thr/c.1153T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),14762,165,15167,"0,0108788818",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,0,Damaging,"26,67","15,58"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,4,106156252,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser385Thr/c.1153T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),22278,334,23172,"0,0144139479",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,0,Damaging,"26,93","15,46"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_032,4,106156252,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser385Thr/c.1153T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),6350,74,6528,"0,0113357843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,0,Damaging,"26,68","15,68"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,4,106156252,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser385Thr/c.1153T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),20060,315,20921,"0,0150566417",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,0,Damaging,"26,95","15,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_034,4,106156252,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser385Thr/c.1153T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),4936,56,5085,"0,0110127827",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,0,Damaging,"26,84","15,93"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106156252,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser385Thr/c.1153T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),28484,429,29642,"0,0144727076",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,0,Damaging,"27,03","16,62"
"low bq, low freq, many artifacts, many samples",UPN2_048,4,106156252,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser385Thr/c.1153T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),5853,66,6046,"0,0109163083",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,0,Damaging,"27,35","15,53"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_035,4,106156252,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser385Thr/c.1153T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),33141,352,33954,"0,0103669671",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,0,Damaging,"26,71","15,3"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_036,4,106156252,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser385Thr/c.1153T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),38675,450,39665,"0,0113450145",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,0,Damaging,"26,65","15,66"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,4,106156252,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser385Thr/c.1153T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),15970,231,16559,"0,0139501178",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,0,Damaging,"26,87","16,13"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,4,106156252,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser385Thr/c.1153T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),19688,257,20447,"0,012569081",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,0,Damaging,"26,97","16,03"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_037,4,106156252,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser385Thr/c.1153T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),18763,230,19288,"0,0119245127",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,0,Damaging,"26,56","15,53"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106156252,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser385Thr/c.1153T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),15860,204,16436,"0,012411779",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,0,Damaging,"27,04","16,12"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,4,106156252,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser385Thr/c.1153T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),17970,238,18655,"0,0127579737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,0,Damaging,"26,95","16,14"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_038,4,106156252,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser385Thr/c.1153T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),27706,360,28497,"0,0126329087",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,0,Damaging,"26,66","15,7"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_039,4,106156252,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser385Thr/c.1153T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),32267,381,33219,"0,0114693398",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,0,Damaging,"26,6","15,73"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,4,106156252,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser385Thr/c.1153T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),23402,337,24346,"0,0138421096",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,0,Damaging,"26,89","15,72"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,4,106156252,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser385Thr/c.1153T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),15220,216,15830,"0,0136449779",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,0,Damaging,"26,9","16,19"
"low bq, low freq, many artifacts, many samples",UPN2_055,4,106156252,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser385Thr/c.1153T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),24096,313,25009,"0,0125154944",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,0,Damaging,"27,02","15,96"
"low bq, low freq, many artifacts, many samples",UPN2_056,4,106156252,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser385Thr/c.1153T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),5826,70,6025,"0,0116182573",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,0,Damaging,"27,1","14,81"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,4,106156252,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser385Thr/c.1153T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),21894,317,22779,"0,0139163264",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,0,Damaging,"26,99","15,42"
"low bq, low freq, many artifacts, many samples",UPN2_058,4,106156252,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser385Thr/c.1153T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),21398,268,22158,"0,0120949544",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,0,Damaging,"27,06","15,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_040,4,106156252,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser385Thr/c.1153T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),49193,542,50452,"0,0107428843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,0,Damaging,"26,71","16,11"
"low bq, low freq, many artifacts",UPN2_013,4,106156252,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser385Thr/c.1153T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),8735,91,8933,"0,0101869473",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,0,Damaging,"27,36","17,95"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_023,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),17911,191,18451,"0,0103517425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"26,7","20,31"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_089,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),12510,182,13375,"0,0136074766",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"26,8","18,19"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),25576,287,26548,"0,0108106072",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"26,96","17,64"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_044,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),2231,28,2320,"0,0120689655",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"26,96","16,21"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),22278,289,23172,"0,0124719489",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"26,93","19,08"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),20060,288,20921,"0,0137660724",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"26,95","17,98"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_034,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),4936,55,5085,"0,0108161259",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"26,84","19,38"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),28484,349,29642,"0,0117738344",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"27,03","18,58"
"low bq, low freq, many artifacts, many samples",UPN2_048,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),5853,61,6046,"0,0100893152",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"27,35","18,95"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),15970,172,16559,"0,0103871007",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"26,87","18,3"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),19688,234,20447,"0,0114442216",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"26,97","18,38"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),15860,184,16436,"0,0111949379",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"27,04","18,1"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),17970,228,18655,"0,0122219244",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"26,95","19,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),23402,296,24346,"0,0121580547",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"26,89","18,56"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),15220,192,15830,"0,0121288692",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"26,9","18,83"
"low bq, low freq, many artifacts, many samples",UPN2_055,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),24096,285,25009,"0,0113958975",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"27,02","18,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_090,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),10278,131,10895,"0,0120238642",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"26,82","16,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),21894,286,22779,"0,0125554239",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"26,99","19,32"
"low bq, low freq, many artifacts, many samples",UPN2_058,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),21398,236,22158,"0,0106507808",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"27,06","19,17"
"low bq, low freq, many artifacts, many samples",UPN2_059,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),22554,482,24870,"0,0193807801",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"27,04","15,77"
"low bq, low freq, many artifacts, many samples",UPN2_060,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),15906,359,17583,"0,0204174487",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"27,11","15,57"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_092,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),6717,94,7201,"0,0130537425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"26,82","16,59"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_093,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),7468,96,7924,"0,0121150934",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"26,69","19,62"
"low bq, many samples",UPN2_061,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),14229,377,15861,"0,0237689931",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"27,13","16,42"
"low bq, many samples",UPN2_062,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),12643,325,14100,"0,0230496454",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"27,17","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_063,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),15371,328,17003,"0,0192907134",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"27,2","16,13"
"low bq, low freq, many artifacts, many samples",UPN2_064,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),14242,346,15728,"0,0219989827",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"27,01","16,27"
"low bq, low freq, many artifacts, many samples",UPN2_065,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),16070,335,17621,"0,0190114068",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"27,03","17,04"
"low bq, low freq, many artifacts, many samples",UPN2_066,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),23750,566,26262,"0,0215520524",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"27,07","16,49"
"low bq, low freq, many artifacts, many samples",UPN2_067,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),29051,548,31842,"0,0172099742",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"27,05","15,62"
"low bq, many samples",UPN2_068,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),17235,420,19067,"0,0220275869",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"27,04","15,6"
"low bq, low freq, many artifacts, many samples",UPN2_069,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),20756,501,22969,"0,0218120075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"27,12",16
"low bq, many samples",UPN2_070,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),12014,307,13355,"0,0229876451",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"27,11","15,92"
"low bq, low freq, many artifacts, many samples",UPN2_071,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),13466,304,14801,"0,0205391528",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"27,1","16,74"
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),13995,298,15419,"0,0193268046",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"27,07","15,95"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),12192,275,13439,"0,0204628321",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"27,08","16,01"
"low bq, low freq, many artifacts, many samples",UPN2_074,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),13561,292,14980,"0,0194926569",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"27,04","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_075,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),18879,388,20765,"0,0186852877",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"27,03","16,62"
"low bq, many samples",UPN2_076,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),16083,398,17828,"0,0223244335",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"27,03","15,91"
"low bq, low freq, many artifacts, many samples",UPN2_077,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),17836,419,19777,"0,0211862264",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"27,1","15,99"
"low bq, many samples",UPN2_078,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),16135,411,18027,"0,0227991346",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"27,13","15,04"
"low bq, many samples",UPN2_079,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),10810,267,11985,"0,0222778473",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"27,27","16,03"
"low bq, low freq, many artifacts, many samples",UPN2_080,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),16645,383,18385,"0,0208322002",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"27,07","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),20444,426,22440,"0,0189839572",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"27,07","16,21"
"low bq, low freq, many artifacts, many samples",UPN2_082,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),26626,572,29391,"0,01946174",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"27,16","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_083,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),20447,483,22705,"0,0212728474",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"27,08",16
"low bq, many samples",UPN2_084,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),23763,587,26383,"0,0222491756",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"27,07","15,91"
"low bq, low freq, many artifacts, many samples",UPN2_085,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),25037,538,27644,"0,0194617277",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"27,03","16,08"
"low bq, low freq, many artifacts, many samples",UPN2_086,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),21656,526,24025,"0,0218938606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"27,07","15,94"
"low bq, low freq, many artifacts, many samples",UPN2_087,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),27445,567,30135,"0,018815331",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"27,11","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_088,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),18820,410,20658,"0,0198470326",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"27,04","16,46"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_094,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),12785,156,13626,"0,011448701",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"26,72","16,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_095,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),13170,180,14080,"0,0127840909",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"26,74","16,96"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_096,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),13254,165,14107,"0,011696321",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"26,82","16,55"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_097,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),12809,178,13619,"0,0130699758",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"26,79","17,79"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_098,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),12720,149,13491,"0,0110444",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"26,76","15,68"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_099,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),7511,98,8006,"0,0122408194",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"26,7","16,92"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_101,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),10990,176,11750,"0,0149787234",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"26,79","17,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_102,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),13231,203,14131,"0,0143655792",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"26,78","16,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_103,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),12617,214,13562,"0,0157793836",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"26,73","17,67"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_104,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),15834,212,16838,"0,012590569",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"26,66","16,66"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_105,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),11777,134,12491,"0,010727724",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"26,73","16,2"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_106,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),18911,230,20071,"0,0114593194",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"26,75","16,75"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_107,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),24536,322,26131,"0,0123225288",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"26,75","17,53"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_108,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),19107,234,20254,"0,0115532734",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"26,68","17,61"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_109,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),19524,253,20799,"0,0121640463",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"26,7","17,46"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_110,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),18881,267,20242,"0,0131903962",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"26,74","17,66"
"low bq, bad alignment, low freq, many artifacts",UPN2_111,4,106156252,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser385Pro/c.1153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),16554,210,17637,"0,0119067869",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,0,Damaging,"26,76","17,27"
"low bq, bad alignment, many samples",UPN2_089,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),12510,587,13375,"0,0438878505",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"26,8","14,55"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),25576,330,26548,"0,0124303149",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"26,96","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),18397,191,19028,"0,010037839",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"27,12","14,26"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_044,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),2231,24,2320,"0,0103448276",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"26,96","14,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),22278,271,23172,"0,0116951493",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"26,93","14,72"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),20060,258,20921,"0,0123321065",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"26,95","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),28484,380,29642,"0,0128196478",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"27,03","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_048,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),5853,66,6046,"0,0109163083",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"27,35","14,47"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),15970,186,16559,"0,0112325624",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"26,87","14,46"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),19688,267,20447,"0,0130581503",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"26,97","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),15860,188,16436,"0,0114383062",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"27,04","14,8"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),17970,219,18655,"0,01173948",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"26,95","14,3"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),23402,311,24346,"0,0127741723",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"26,89","14,68"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),15220,202,15830,"0,0127605812",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"26,9","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_055,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),24096,315,25009,"0,0125954656",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"27,02","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_056,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),5826,72,6025,"0,0119502075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"27,1","14,78"
"low bq, bad alignment, many samples",UPN2_090,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),10278,428,10895,"0,0392840753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"26,82","14,71"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),21894,282,22779,"0,0123798235",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"26,99","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_058,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),21398,256,22158,"0,0115533893",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"27,06","14,59"
"inspected, strandbias, low bq, many samples",UPN2_059,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),22554,1705,24870,"0,0685564938",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"27,04","15,52"
"low bq, many samples",UPN2_060,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),15906,1209,17583,"0,0687595973",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"27,11","15,3"
"low bq, bad alignment, many samples",UPN2_091,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),9528,393,10088,"0,0389571768",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"26,75","14,72"
"low bq, bad alignment, many samples",UPN2_092,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),6717,353,7201,"0,0490209693",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"26,82","14,65"
"low bq, bad alignment, many samples",UPN2_093,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),7468,326,7924,"0,041140838",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"26,69","14,48"
"strandbias, low bq, many samples",UPN2_061,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),14229,1159,15861,"0,0730723157",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"27,13","15,23"
"low bq, many samples",UPN2_062,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),12643,1060,14100,"0,075177305",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"27,17","15,44"
"strandbias, low bq, many samples",UPN2_063,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),15371,1229,17003,"0,0722813621",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"27,2","15,42"
"strandbias, low bq, many samples",UPN2_064,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),14242,1075,15728,"0,0683494405",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"27,01","15,54"
"strandbias, low bq, many samples",UPN2_065,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),16070,1123,17621,"0,0637307758",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"27,03","15,47"
"strandbias, low bq, many samples",UPN2_066,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),23750,1808,26262,"0,0688447186",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"27,07","15,5"
"strandbias, low bq, many samples",UPN2_067,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),29051,2119,31842,"0,0665473274",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"27,05","15,42"
"strandbias, low bq, many samples",UPN2_068,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),17235,1321,19067,"0,0692820056",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"27,04","15,35"
"strandbias, low bq, many samples",UPN2_069,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),20756,1595,22969,"0,069441421",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"27,12","15,5"
"strandbias, low bq, many samples",UPN2_070,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),12014,953,13355,"0,0713590416",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"27,11","15,68"
"strandbias, low bq, many samples",UPN2_071,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),13466,963,14801,"0,0650631714",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"27,1","15,37"
"strandbias, low bq, many samples",UPN2_072,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),13995,1051,15419,"0,0681626565",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"27,07","15,52"
"strandbias, low bq, many samples",UPN2_073,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),12192,903,13439,"0,0671924994",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"27,08","15,53"
"low bq, many samples",UPN2_074,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),13561,1046,14980,"0,0698264352",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"27,04","15,35"
"strandbias, low bq, many samples",UPN2_075,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),18879,1380,20765,"0,0664579822",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"27,03","15,46"
"strandbias, low bq, many samples",UPN2_076,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),16083,1262,17828,"0,0707875252",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"27,03","15,52"
"strandbias, low bq, many samples",UPN2_077,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),17836,1405,19777,"0,0710421196",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"27,1","15,54"
"strandbias, low bq, many samples",UPN2_078,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),16135,1395,18027,"0,0773839241",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"27,13","15,42"
"low bq, many samples",UPN2_079,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),10810,839,11985,"0,0700041719",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"27,27","15,42"
"strandbias, low bq, many samples",UPN2_080,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),16645,1257,18385,"0,0683709546",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"27,07","15,44"
"strandbias, low bq, many samples",UPN2_081,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),20444,1460,22440,"0,0650623886",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"27,07","15,49"
"strandbias, low bq, many samples",UPN2_082,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),26626,2058,29391,"0,0700214351",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"27,16","15,44"
"strandbias, low bq, many samples",UPN2_083,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),20447,1665,22705,"0,0733318652",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"27,08","15,34"
"strandbias, low bq, many samples",UPN2_084,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),23763,1897,26383,"0,0719023614",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"27,07","15,51"
"strandbias, low bq, many samples",UPN2_085,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),25037,1926,27644,"0,0696715381",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"27,03","15,26"
"low bq, many samples",UPN2_086,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),21656,1731,24025,"0,072049948",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"27,07","15,27"
"strandbias, low bq, many samples",UPN2_087,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),27445,1990,30135,"0,0660361706",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"27,11","15,66"
"low bq, many samples",UPN2_088,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),18820,1332,20658,"0,0644786523",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"27,04","15,4"
"low bq, bad alignment, many samples",UPN2_094,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),12785,599,13626,"0,0439600763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"26,72","14,62"
"low bq, bad alignment, many samples",UPN2_095,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),13170,644,14080,"0,0457386364",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"26,74","14,31"
"low bq, bad alignment, many samples",UPN2_096,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),13254,596,14107,"0,0422485291",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"26,82","14,52"
"low bq, bad alignment, many samples",UPN2_097,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),12809,557,13619,"0,0408987444",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"26,79","14,48"
"low bq, bad alignment, many samples",UPN2_098,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),12720,548,13491,"0,0406196724",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"26,76","14,49"
"low bq, bad alignment, many samples",UPN2_099,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),7511,349,8006,"0,0435923058",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"26,7","14,48"
"low bq, bad alignment, many samples",UPN2_100,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),11405,467,12060,"0,0387230514",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"26,79","14,39"
"low bq, bad alignment, many samples",UPN2_101,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),10990,507,11750,"0,0431489362",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"26,79","14,45"
"low bq, bad alignment, many samples",UPN2_102,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),13231,594,14131,"0,0420352417",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"26,78","14,49"
"low bq, bad alignment, many samples",UPN2_103,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),12617,640,13562,"0,0471906798",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"26,73","14,24"
"low bq, bad alignment, many samples",UPN2_104,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),15834,707,16838,"0,0419883597",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"26,66","14,62"
"low bq, bad alignment, many samples",UPN2_105,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),11777,513,12491,"0,0410695701",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"26,73","14,7"
"low bq, bad alignment, many samples",UPN2_106,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),18911,822,20071,"0,0409546111",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"26,75","14,5"
"low bq, bad alignment, many samples",UPN2_107,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),24536,1136,26131,"0,0434732693",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"26,75","14,43"
"low bq, bad alignment, many samples",UPN2_108,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),19107,799,20254,"0,0394489977",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"26,68","14,53"
"low bq, bad alignment, many samples",UPN2_109,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),19524,895,20799,"0,0430309149",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"26,7","14,58"
"low bq, bad alignment, many samples",UPN2_110,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),18881,938,20242,"0,0463392945",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"26,74","14,49"
"low bq, bad alignment",UPN2_111,4,106156252,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser385Ala/c.1153T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),16554,780,17637,"0,0442252084",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,0,Damaging,"26,76","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106156258,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe387Ile/c.1159T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),26213,292,26775,"0,0109056956",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,23",Neutral,5,Damaging,"28,31","16,99"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106156258,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe387Ile/c.1159T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),18833,193,19196,"0,010054178",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,23",Neutral,5,Damaging,"28,48","16,77"
"low bq, low freq, many artifacts, many samples",UPN2_046,4,106156258,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe387Ile/c.1159T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),20621,220,21065,"0,0104438642",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,23",Neutral,5,Damaging,"28,2","16,5"
"low bq, low freq, many artifacts, many samples",UPN2_048,4,106156258,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe387Ile/c.1159T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),5975,80,6110,"0,0130932897",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,23",Neutral,5,Damaging,"28,69","18,33"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106156258,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe387Ile/c.1159T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),16303,174,16634,"0,0104605026",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,23",Neutral,5,Damaging,"28,42","17,02"
"low bq, low freq, many artifacts, many samples",UPN2_053,4,106156258,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe387Ile/c.1159T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),24013,268,24494,"0,0109414551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,23",Neutral,5,Damaging,"28,21","17,95"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,4,106156258,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe387Ile/c.1159T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),16709,185,17240,"0,0107308585",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,23",Neutral,5,Damaging,"26,7","15,97"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,4,106156258,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe387Ile/c.1159T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),15446,168,15879,"0,0105800113",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,23",Neutral,5,Damaging,"26,53","17,44"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_065,4,106156258,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe387Ile/c.1159T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),17304,178,17786,"0,0100078714",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,23",Neutral,5,Damaging,"26,88","15,92"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_067,4,106156258,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe387Ile/c.1159T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),31201,325,32096,"0,0101258724",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,23",Neutral,5,Damaging,"26,79","16,55"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_068,4,106156258,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe387Ile/c.1159T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),18642,209,19229,"0,0108689999",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,23",Neutral,5,Damaging,"26,44","16,38"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_069,4,106156258,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe387Ile/c.1159T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),22513,259,23222,"0,0111532168",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,23",Neutral,5,Damaging,"26,65",16
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,4,106156258,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe387Ile/c.1159T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),13163,154,13581,"0,0113393712",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,23",Neutral,5,Damaging,"26,73","16,38"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,4,106156258,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe387Ile/c.1159T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),17488,194,18001,"0,010777179",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,23",Neutral,5,Damaging,"26,53","15,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,4,106156258,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe387Ile/c.1159T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),19395,207,19989,"0,0103556956",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,23",Neutral,5,Damaging,"26,48","16,91"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,4,106156258,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe387Ile/c.1159T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),17676,186,18245,"0,0101945739",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,23",Neutral,5,Damaging,"26,45","16,24"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_079,4,106156258,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe387Ile/c.1159T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),11785,127,12116,"0,0104820073",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,23",Neutral,5,Damaging,"26,69","17,03"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,4,106156258,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe387Ile/c.1159T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),17988,209,18552,"0,0112656317",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,23",Neutral,5,Damaging,"26,67",17
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_082,4,106156258,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe387Ile/c.1159T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),28893,299,29696,"0,0100686961",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,23",Neutral,5,Damaging,"26,71","16,43"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,4,106156258,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe387Ile/c.1159T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),25891,285,26649,"0,0106945852",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,23",Neutral,5,Damaging,"26,55","14,94"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_085,4,106156258,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe387Ile/c.1159T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),27076,298,27913,"0,0106760291",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,23",Neutral,5,Damaging,"26,62","15,94"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,4,106156258,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe387Ile/c.1159T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),23560,257,24311,"0,0105713463",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,23",Neutral,5,Damaging,"26,55","16,31"
"low bq, bad alignment, low freq, many artifacts",UPN2_088,4,106156258,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe387Ile/c.1159T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),20270,218,20836,"0,0104626608",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,23",Neutral,5,Damaging,"26,81","16,56"
"low bq, bad alignment, low freq, many artifacts",UPN2_086,4,106156258,T,C,missense_variant(MODERATE|MISSENSE|Ttc/Ctc|p.Phe387Leu/c.1159T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),23560,246,24311,"0,0101188762",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,29",Neutral,12,Damaging,"26,55","22,17"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_059,4,106156258,T,G,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe387Val/c.1159T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),24398,265,25113,"0,0105523036",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,65",Deleterious,5,Damaging,"26,76","14,82"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,4,106156258,T,G,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe387Val/c.1159T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),15548,164,16004,"0,0102474381",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,65",Deleterious,5,Damaging,"26,5","14,57"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,4,106156258,T,G,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe387Val/c.1159T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),16709,197,17240,"0,0114269142",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,65",Deleterious,5,Damaging,"26,7","14,41"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_066,4,106156258,T,G,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe387Val/c.1159T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),25791,277,26561,"0,0104288242",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,65",Deleterious,5,Damaging,"26,63","14,4"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_068,4,106156258,T,G,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe387Val/c.1159T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),18642,213,19229,"0,0110770191",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,65",Deleterious,5,Damaging,"26,44","14,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_069,4,106156258,T,G,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe387Val/c.1159T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),22513,239,23222,"0,0102919645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,65",Deleterious,5,Damaging,"26,65","14,51"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_070,4,106156258,T,G,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe387Val/c.1159T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),13088,149,13494,"0,0110419446",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,65",Deleterious,5,Damaging,"26,53","14,36"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,4,106156258,T,G,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe387Val/c.1159T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),14572,152,14991,"0,010139417",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,65",Deleterious,5,Damaging,"26,63","14,57"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,4,106156258,T,G,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe387Val/c.1159T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),15138,166,15574,"0,0106587903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,65",Deleterious,5,Damaging,"26,63","15,02"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,4,106156258,T,G,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe387Val/c.1159T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),14682,157,15094,"0,010401484",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,65",Deleterious,5,Damaging,"26,6","14,55"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_075,4,106156258,T,G,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe387Val/c.1159T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),20394,218,20976,"0,0103928299",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,65",Deleterious,5,Damaging,"26,79","14,47"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,4,106156258,T,G,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe387Val/c.1159T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),19395,206,19989,"0,0103056681",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,65",Deleterious,5,Damaging,"26,48","14,46"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,4,106156258,T,G,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe387Val/c.1159T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),17676,207,18245,"0,0113455741",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,65",Deleterious,5,Damaging,"26,45","14,86"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_081,4,106156258,T,G,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe387Val/c.1159T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),22068,232,22699,"0,0102207146",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,65",Deleterious,5,Damaging,"26,81","14,53"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_085,4,106156258,T,G,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe387Val/c.1159T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),27076,291,27913,"0,0104252499",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,65",Deleterious,5,Damaging,"26,62","14,71"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,4,106156258,T,G,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe387Val/c.1159T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),23560,248,24311,"0,0102011435",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,65",Deleterious,5,Damaging,"26,55","14,19"
"low bq, bad alignment, low freq, many artifacts",UPN2_087,4,106156258,T,G,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe387Val/c.1159T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),29578,342,30438,"0,0112359551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,65",Deleterious,5,Damaging,"26,8","14,98"
inspected,UPN2_044,4,106156266,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys389Asn/c.1167G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),2215,111,2330,"0,047639485",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,06",Neutral,"0,004",Damaging,"31,27","31,32"
"low bq, low freq, many artifacts",UPN2_048,4,106156267,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp390Tyr/c.1168G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),6025,83,6120,"0,0135620915",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,55",Deleterious,"0,001",Damaging,"32,44","26,29"
"low bq, low freq, many artifacts, many samples",UPN2_061,4,106156275,T,A,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe392Leu/c.1176T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),15860,168,16129,"0,0104160208",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,482,Tolerated,"30,15","16,98"
"low bq, low freq, many artifacts, many samples",UPN2_062,4,106156275,T,A,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe392Leu/c.1176T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),14199,153,14398,"0,0106264759",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,482,Tolerated,"29,96","16,59"
"low bq, low freq, many artifacts, many samples",UPN2_069,4,106156275,T,A,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe392Leu/c.1176T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),23119,240,23439,"0,0102393447",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,482,Tolerated,"30,19","16,45"
"CAC repeat, many artifacts, low freq, many samples",UPN2_001,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),10667,112,10817,"0,0103540723",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,52",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_014,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),15707,208,15950,"0,0130407524",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,31",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_016,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),9556,100,9684,"0,0103263114",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,32",NA
"low freq, many artifacts, many samples",UPN2_017,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),7503,77,7605,"0,0101249178",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,28",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_018,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),11236,161,11421,"0,0140968392",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,31",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_019,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),12772,156,12961,"0,0120361083",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,33",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_020,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),9823,128,9983,"0,0128217971",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,27",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_002,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),15309,185,15542,"0,01190323",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,44",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_003,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),2749,28,2786,"0,0100502513",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,38",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_022,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),17075,209,17309,"0,0120746432",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,33",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_023,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),18380,188,18604,"0,0101053537",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,31",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_026,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),19798,255,20109,"0,0126808892",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,39",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_004,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),1970,28,2007,"0,0139511709",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,36",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_027,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),21827,245,22138,"0,0110669437",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,33",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_089,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),13367,138,13533,"0,0101972955",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,11",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_028,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),15505,187,15726,"0,0118911357",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,38",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_043,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),18913,247,19264,"0,0128218439",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"33,83",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_044,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),2288,38,2332,"0,0162950257",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"33,9",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_029,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),17836,241,18135,"0,0132892197",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,33",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_030,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),15044,186,15261,"0,01218793",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,37",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_031,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),10977,119,11111,"0,0107101071",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,19",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_046,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),20829,221,21141,"0,0104536209",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"33,81",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_033,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),13447,159,13630,"0,0116654439",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,24",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_047,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),29474,346,29951,"0,0115522019",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"33,8",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_035,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),33754,364,34223,"0,0106361219",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,28",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_036,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),39565,415,40064,"0,0103584265",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,33",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_006,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),15835,247,16236,"0,0152131067",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,37",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_050,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),20331,225,20655,"0,0108932462",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"33,87",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_037,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),19231,201,19469,"0,010324105",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,42",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_052,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),18541,243,18868,"0,0128789485",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"33,9",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_038,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),28221,350,28635,"0,0122228043",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,36",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_039,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),33119,380,33570,"0,0113196306",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,39",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_054,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),15776,181,16023,"0,0112962616",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"33,86",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_007,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),32671,423,33211,"0,0127367438",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,3",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_008,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),44338,572,45038,"0,0127003863",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,38",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_009,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),36638,388,37120,"0,0104525862",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,4",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_010,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),25472,320,25869,"0,0123700182",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,38",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_011,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),30487,375,31004,"0,0120952135",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,32",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_055,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),24895,286,25293,"0,0113074764",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"33,85",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_090,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),10841,136,11021,"0,012340078",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,09",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_058,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),22048,259,22376,"0,0115749017",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"33,81",NA
"inspected, CAC repeat, many artifacts, low freq, many samples",UPN2_059,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),24958,281,25340,"0,0110891871",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"33,28",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_012,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),14464,153,14655,"0,0104401228",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,29",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_060,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),17591,241,17918,"0,0134501618",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"33,36",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_040,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),50243,531,50901,"0,0104320151",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,34",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_013,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),8886,99,9014,"0,0109829155",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,31",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_091,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),10073,117,10221,"0,0114470208",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,1",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_092,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),7200,84,7298,"0,0115100027",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,13",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_093,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),7879,91,7997,"0,0113792672",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,1",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_061,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),15892,201,16152,"0,0124442793",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"33,43",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_063,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),17149,197,17404,"0,011319237",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"33,35",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_065,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),17636,233,17947,"0,0129826712",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"33,27",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_066,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),26406,288,26812,"0,010741459",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"33,26",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_067,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),31928,350,32409,"0,0107994693",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"33,33",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_068,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),19104,243,19409,"0,012519965",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"33,41",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_069,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),23070,267,23473,"0,011374771",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"33,3",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_070,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),13376,183,13616,"0,0134400705",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"33,4",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_071,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),14898,165,15122,"0,0109112551",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"33,26",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_072,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),15487,158,15707,"0,0100592093",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"33,31",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_073,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),13440,170,13702,"0,0124069479",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"33,24",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_076,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),17840,239,18164,"0,0131578947",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"33,38",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_077,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),19856,240,20184,"0,0118906064",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"33,36",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_078,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),18146,215,18431,"0,0116651294",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"33,42",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_079,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),12004,137,12220,"0,0112111293",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"33,31",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_080,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),18408,220,18708,"0,011759675",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"33,41",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_081,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),22558,234,22885,"0,0102250382",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"33,27",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_082,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),29443,367,29943,"0,0122566209",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"33,36",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_083,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),22850,256,23194,"0,0110373372",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"33,37",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_085,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),27674,324,28131,"0,0115175429",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"33,35",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_086,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),24115,289,24511,"0,0117906246",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"33,43",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_087,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),30219,356,30703,"0,0115949581",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"33,29",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_088,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),20695,229,21030,"0,0108892059",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"33,24",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_095,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),14042,158,14252,"0,0110861633",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,02",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_096,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),14048,158,14252,"0,0110861633",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,12",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_097,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),13508,173,13735,"0,0125955588",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,08",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_098,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),13416,145,13606,"0,0106570631",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,12",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_099,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),7978,96,8091,"0,0118650352",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,18",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_104,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),16823,191,17065,"0,0111924993",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,12",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_106,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),20011,206,20291,"0,0101522843",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,1",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_107,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),26077,270,26450,"0,0102079395",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,04",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_108,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),20127,252,20442,"0,0123275609",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,1",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_109,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),20708,240,21008,"0,0114242193",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,12",NA
"CAC repeat, many artifacts, low freq, many samples",UPN2_111,4,106156288,ACAC,A,inframe_deletion(MODERATE||cca/|p.Pro401del/c.1201_1203delCCA|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),17561,205,17817,"0,0115058652",1,0,0,1,0,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,24",Neutral,NA,NA,"34,14",NA
"low freq, many artifacts, many samples",UPN2_044,4,106156300,C,T,missense_variant(MODERATE|MISSENSE|Cca/Tca|p.Pro401Ser/c.1201C>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),2286,31,2332,"0,0132933105",0,0,0,0,0,0,0,1,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,41",Neutral,175,Tolerated,"32,92","32,77"
"many samples, low freq, no database",UPN2_030,4,106156300,C,T,missense_variant(MODERATE|MISSENSE|Cca/Tca|p.Pro401Ser/c.1201C>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),15064,155,15260,"0,0101572739",0,0,0,0,0,1,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,41",Neutral,"0,175",Tolerated,"32,9","33,6"
"many samples, low freq, no database",UPN2_032,4,106156300,C,T,missense_variant(MODERATE|MISSENSE|Cca/Tca|p.Pro401Ser/c.1201C>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),6476,70,6569,"0,010656112",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,41",Neutral,"0,175",Tolerated,"32,87","34,56"
"many samples, low freq, no database",UPN2_046,4,106156300,C,T,missense_variant(MODERATE|MISSENSE|Cca/Tca|p.Pro401Ser/c.1201C>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),20817,233,21137,"0,011023324",0,0,0,0,0,1,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,41",Neutral,"0,175",Tolerated,"32,93","33,31"
"many samples, low freq, no database",UPN2_049,4,106156300,C,T,missense_variant(MODERATE|MISSENSE|Cca/Tca|p.Pro401Ser/c.1201C>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),16402,205,16686,"0,0122857485",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,41",Neutral,"0,175",Tolerated,"32,89","34,28"
"many samples, low freq, no database",UPN2_056,4,106156300,C,T,missense_variant(MODERATE|MISSENSE|Cca/Tca|p.Pro401Ser/c.1201C>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),5973,72,6100,"0,0118032787",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,41",Neutral,"0,175",Tolerated,"32,98","33,67"
"many samples, low freq, no database",UPN2_063,4,106156300,C,T,missense_variant(MODERATE|MISSENSE|Cca/Tca|p.Pro401Ser/c.1201C>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),17069,199,17405,"0,0114334961",0,0,0,0,0,1,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,41",Neutral,"0,175",Tolerated,"32,45","32,89"
"many samples, low freq, no database",UPN2_076,4,106156300,C,T,missense_variant(MODERATE|MISSENSE|Cca/Tca|p.Pro401Ser/c.1201C>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),17870,201,18164,"0,0110658445",0,0,0,0,0,1,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,41",Neutral,"0,175",Tolerated,"32,52","32,99"
"many samples, low freq, no database",UPN2_080,4,106156300,C,T,missense_variant(MODERATE|MISSENSE|Cca/Tca|p.Pro401Ser/c.1201C>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),18393,219,18722,"0,0116974682",0,0,0,0,0,1,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,41",Neutral,"0,175",Tolerated,"32,4","33,18"
inspected,UPN2_044,4,106156306,C,T,stop_gained(HIGH|NONSENSE|Caa/Taa|p.Gln403*/c.1207C>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),2216,108,2331,"0,0463320463",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,2","33,06"
"low freq, many artifacts",UPN2_056,4,106156325,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro409Leu/c.1226C>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),5981,62,6062,"0,0102276476",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,31",Neutral,"0,712",Tolerated,"29,75","30,26"
many samples,UPN2_001,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),12377,447,12865,"0,0347454333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,17","31,26"
many samples,UPN2_014,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),18227,483,18760,"0,0257462687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,21","31,29"
"low freq, many artifacts, many samples",UPN2_015,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),23550,423,24043,"0,0175934784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,23","31,4"
many samples,UPN2_016,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),11836,294,12163,"0,0241716682",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,12","31,47"
"strandbias, many samples",UPN2_017,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),8772,239,9027,"0,0264761272",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,19","31,69"
many samples,UPN2_018,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),13030,299,13361,"0,0223785645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,22","31,64"
many samples,UPN2_019,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),15054,427,15515,"0,0275217531",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,22","31,6"
many samples,UPN2_020,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),11294,305,11624,"0,0262388162",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,27","31,6"
many samples,UPN2_021,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),12899,321,13250,"0,0242264151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,21","31,07"
many samples,UPN2_002,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),16243,619,16896,"0,0366358902",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,28","31,26"
many samples,UPN2_003,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),3006,104,3111,"0,0334297653",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,19","31,34"
"strandbias, many samples",UPN2_022,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),19485,435,19961,"0,0217924954",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,27","31,36"
"low freq, many artifacts, many samples",UPN2_023,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),20732,444,21219,"0,020924643",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,29","31,19"
"low freq, many artifacts, many samples",UPN2_024,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),9804,177,10004,"0,0176929228",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,2","31,61"
"strandbias, many samples",UPN2_025,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),21504,525,22087,"0,0237696382",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,22","31,35"
"strandbias, many samples",UPN2_026,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),22846,516,23422,"0,0220305695",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,26","31,57"
many samples,UPN2_004,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),1752,61,1829,"0,0333515582",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,54","30,93"
"strandbias, many samples",UPN2_027,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),24290,661,25010,"0,0264294282",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,33","31,29"
"strandbias, many samples",UPN2_028,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),17879,447,18376,"0,0243252068",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,28","31,42"
"low freq, many artifacts, many samples",UPN2_044,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),3849,65,3919,"0,0165858637",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"32,61","30,38"
many samples,UPN2_029,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),20322,547,20921,"0,0261459777",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,26","31,3"
many samples,UPN2_030,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),18472,444,18957,"0,0234214274",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,15","31,5"
"strandbias, many samples",UPN2_031,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),12680,293,13008,"0,0225246002",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,25","31,12"
many samples,UPN2_005,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),4497,175,4684,"0,0373612297",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,17","31,38"
"low freq, many artifacts, many samples",UPN2_032,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),7525,169,7709,"0,0219224283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,23","31,79"
"low freq, many artifacts, many samples",UPN2_046,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),24352,344,24752,"0,0138978668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"32,94","31,13"
"low freq, many artifacts, many samples",UPN2_033,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),15323,337,15700,"0,0214649682",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,23","31,29"
"strandbias, many samples",UPN2_034,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),5797,130,5943,"0,0218744742",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,29","31,68"
"strandbias, many samples",UPN2_047,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),28880,322,29275,"0,010999146",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,15","30,09"
"strandbias, many samples",UPN2_035,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),36023,773,36889,"0,0209547562",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,35","31,5"
"strandbias, many samples",UPN2_036,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),37983,761,38834,"0,0195962301",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,5","31,48"
many samples,UPN2_006,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),16508,606,17137,"0,035362082",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,32","31,31"
"inspected, strandbias, many samples",UPN2_049,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),17304,196,17557,"0,0111636384",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,06","30,68"
"low freq, many artifacts, many samples",UPN2_037,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),23436,428,23922,"0,0178914806",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,19","31,51"
"strandbias, many samples",UPN2_038,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),32663,693,33453,"0,0207156309",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,26","31,4"
"low freq, many artifacts, many samples",UPN2_039,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),32794,578,33443,"0,0172831385",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,49","31,22"
"strandbias, many samples",UPN2_053,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),28379,372,28830,"0,0129032258",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"32,97",31
"strandbias, many samples",UPN2_007,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),36128,980,37236,"0,0263186164",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,19","31,14"
many samples,UPN2_008,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),47131,1150,48385,"0,0237676966",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,24","31,32"
"low freq, many artifacts, many samples",UPN2_009,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),38048,775,38921,"0,0199121297",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,27","31,17"
many samples,UPN2_010,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),27645,663,28393,"0,0233508259",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,21","31,47"
many samples,UPN2_011,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),32670,867,33615,"0,0257920571",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,22","31,08"
"low freq, many artifacts, many samples",UPN2_057,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),25624,310,25984,"0,0119304187",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"32,93","31,24"
"strandbias, many samples",UPN2_058,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),26174,412,26659,"0,0154544432",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"32,92","30,9"
"strandbias, many samples",UPN2_059,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),18310,260,18626,"0,0139589821",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,64","29,43"
many samples,UPN2_012,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),16340,426,16806,"0,02534809",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,1","31,32"
"strandbias, many samples",UPN2_060,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),15820,399,16262,"0,0245357275",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,25","31,03"
"strandbias, many samples",UPN2_040,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),49896,962,50956,"0,0188790329",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,5","31,33"
"strandbias, many samples",UPN2_013,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),9499,235,9759,"0,0240803361",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,17","31,23"
many samples,UPN2_061,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),15917,468,16431,"0,028482746",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,13","30,81"
many samples,UPN2_062,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),11946,303,12284,"0,0246662325",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,46","30,85"
"strandbias, many samples",UPN2_063,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),15798,466,16297,"0,0285942198",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,25","30,9"
"strandbias, many samples",UPN2_064,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),13347,379,13766,"0,0275315996",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,42","30,94"
many samples,UPN2_065,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),16238,366,16626,"0,0220137135",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,21","30,46"
many samples,UPN2_066,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),26320,655,27046,"0,024217999",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,1","30,6"
"strandbias, many samples",UPN2_067,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),31829,776,32687,"0,0237403249",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,13","30,58"
many samples,UPN2_068,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),20041,550,20630,"0,0266602036",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,07","30,88"
many samples,UPN2_069,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),21616,529,22198,"0,0238309758",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,23","30,78"
many samples,UPN2_070,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),13580,397,14003,"0,0283510676",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,06","31,01"
"low freq, many artifacts, many samples",UPN2_071,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),10791,210,11026,"0,0190458915",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,65","30,81"
"strandbias, many samples",UPN2_072,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),12483,275,12782,"0,0215146299",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,39","30,54"
"strandbias, many samples",UPN2_073,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),11952,227,12210,"0,0185913186",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,24","30,75"
"low freq, many artifacts, many samples",UPN2_074,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),14420,290,14754,"0,0196556866",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,16","30,66"
"strandbias, many samples",UPN2_075,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),18150,357,18561,"0,0192338775",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,33","30,58"
"strandbias, many samples",UPN2_076,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),17441,375,17852,"0,0210060497",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,17","30,83"
"strandbias, many samples",UPN2_077,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),20374,437,20846,"0,0209632543",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,08","30,97"
"low freq, many artifacts, many samples",UPN2_078,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),16237,307,16588,"0,0185073547",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,33","30,37"
"strandbias, many samples",UPN2_079,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),10772,210,11002,"0,0190874386",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,29","30,43"
"low freq, many artifacts, many samples",UPN2_080,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),15085,298,15413,"0,0193343282",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,42","30,82"
"low freq, many artifacts, many samples",UPN2_081,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),18073,260,18376,"0,0141488899",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,41","30,62"
"low freq, many artifacts, many samples",UPN2_082,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),27310,475,27861,"0,0170489214",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,23","30,91"
"strandbias, many samples",UPN2_083,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),22178,612,22846,"0,0267880592",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,19","30,93"
"strandbias, many samples",UPN2_084,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),25786,525,26381,"0,0199006861",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,19","30,82"
"strandbias, many samples",UPN2_085,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),24304,378,24754,"0,0152702594",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,37","30,16"
"strandbias, many samples",UPN2_086,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),19743,279,20093,"0,0138854327",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,48","30,43"
"strandbias, many samples",UPN2_087,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),28045,534,28660,"0,0186322401",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,24","30,43"
"inspected, low freq, neutral effect",UPN2_088,4,106156348,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln417Glu/c.1249C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),19792,512,20354,"0,0251547607",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,12",Tolerated,"33,16","30,53"
"low freq, many artifacts",UPN2_004,4,106156357,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser420Ala/c.1258T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),1810,25,1839,"0,0135943448",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,78,Tolerated,"35,4","35,12"
"low freq, many artifacts",UPN2_056,4,106156387,GT,G,frameshift_variant(HIGH||tta/|p.Leu431fs/c.1292delT|2002|TET2|protein_coding|CODING|ENST00000380013|3|G|INFO_REALIGN_3_PRIME),5202,55,5304,"0,0103695324",1,0,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,94",NA
"low freq, many artifacts",UPN2_044,4,106156393,G,A,missense_variant(MODERATE|MISSENSE|Gaa/Aaa|p.Glu432Lys/c.1294G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),3958,52,4017,"0,0129449838",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,4,Damaging,"35,08","35,67"
"low bq, many samples, no database, low freq",UPN2_048,4,106156403,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His435Pro/c.1304A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),1406,43,1462,"0,0294117647",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,071",Tolerated,"31,58","29,23"
"low bq, many samples, no database, low freq",UPN2_056,4,106156403,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His435Pro/c.1304A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),2278,37,2325,"0,0159139785",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,071",Tolerated,"32,12",31
"low bq, many samples, no database, low freq",UPN2_059,4,106156403,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His435Pro/c.1304A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),6079,67,6169,"0,0108607554",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,071",Tolerated,"30,35","26,57"
"low bq, many samples, no database, low freq",UPN2_060,4,106156403,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His435Pro/c.1304A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),7365,88,7486,"0,0117552765",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,071",Tolerated,"29,97","25,2"
"low bq, many samples, no database, low freq",UPN2_092,4,106156403,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His435Pro/c.1304A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),5307,58,5378,"0,0107846783",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,071",Tolerated,"31,99","30,59"
"low bq, many samples, no database, low freq",UPN2_063,4,106156403,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His435Pro/c.1304A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),7665,95,7805,"0,0121716848",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,071",Tolerated,"30,12","26,01"
"low bq, many samples, no database, low freq",UPN2_064,4,106156403,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His435Pro/c.1304A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),5807,75,5913,"0,0126839168",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,071",Tolerated,"30,26","25,15"
"low bq, many samples, no database, low freq",UPN2_071,4,106156403,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His435Pro/c.1304A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),3558,71,3641,"0,0195001373",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,071",Tolerated,"29,97","28,65"
"low bq, many samples, no database, low freq",UPN2_078,4,106156403,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His435Pro/c.1304A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),7430,97,7566,"0,0128205128",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,071",Tolerated,"29,91","26,34"
"low bq, many samples, no database, low freq",UPN2_079,4,106156403,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His435Pro/c.1304A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),4926,56,5005,"0,0111888112",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,071",Tolerated,"30,26","27,95"
"low bq, many samples, no database, low freq",UPN2_080,4,106156403,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His435Pro/c.1304A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),6176,75,6268,"0,0119655392",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,071",Tolerated,"30,36","26,13"
"low bq, many samples, no database, low freq",UPN2_081,4,106156403,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His435Pro/c.1304A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),7014,102,7163,"0,0142398436",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,071",Tolerated,"30,26","26,27"
"low bq, low freq, many artifacts",UPN2_082,4,106156403,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His435Pro/c.1304A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),13042,140,13253,"0,010563646",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,71,Tolerated,"30,18","24,35"
"low bq, many samples, no database, low freq",UPN2_086,4,106156403,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His435Pro/c.1304A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),7956,92,8098,"0,0113608298",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,071",Tolerated,"30,21","27,7"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106156408,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr437Asn/c.1309T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),11453,122,11616,"0,0105027548",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,0,Damaging,"34,06","18,98"
"low bq, low freq, many artifacts, many samples",UPN2_044,4,106156408,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr437Asn/c.1309T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),2735,36,2776,"0,0129682997",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,0,Damaging,"34,07","18,56"
"low bq, low freq, many artifacts, many samples",UPN2_005,4,106156408,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr437Asn/c.1309T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),2667,28,2698,"0,0103780578",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,0,Damaging,"34,42","17,14"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106156408,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr437Asn/c.1309T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),14359,163,14562,"0,0111935174",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,0,Damaging,"34,11","18,64"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106156408,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr437Asn/c.1309T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),9172,130,9326,"0,0139395239",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,0,Damaging,"34,02","22,06"
"low bq, low freq, many artifacts, many samples",UPN2_050,4,106156408,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr437Asn/c.1309T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),14408,161,14618,"0,0110138186",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,0,Damaging,"34,16","18,64"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106156408,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr437Asn/c.1309T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),12533,141,12724,"0,0110814209",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,0,Damaging,"34,05","19,06"
"low bq, low freq, many artifacts, many samples",UPN2_052,4,106156408,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr437Asn/c.1309T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),12697,146,12898,"0,0113195844",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,0,Damaging,"34,2","18,27"
"low bq, low freq, many artifacts, many samples",UPN2_053,4,106156408,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr437Asn/c.1309T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),16570,183,16812,"0,0108850821",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,0,Damaging,"34,13","19,33"
"low bq, low freq, many artifacts, many samples",UPN2_055,4,106156408,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr437Asn/c.1309T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),16964,217,17255,"0,0125760649",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,0,Damaging,"34,04","20,17"
"low bq, low freq, many artifacts, many samples",UPN2_056,4,106156408,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr437Asn/c.1309T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),2255,29,2291,"0,0126582278",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,0,Damaging,"34,14","15,62"
"low bq, low freq, many artifacts, many samples",UPN2_058,4,106156408,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr437Asn/c.1309T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),15480,184,15711,"0,0117115397",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,0,Damaging,"34,04","19,92"
"low bq, low freq, many artifacts",UPN2_013,4,106156408,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr437Asn/c.1309T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),5287,57,5353,"0,0106482346",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,0,Damaging,"34,38","18,39"
"low freq, many artifacts",UPN2_056,4,106156418,A,G,missense_variant(MODERATE|MISSENSE|cAa/cGa|p.Gln440Arg/c.1319A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),2255,28,2291,"0,0122217372",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,63",Neutral,"0,412",Tolerated,"34,29","33,21"
"low bq, low freq, many artifacts",UPN2_048,4,106156435,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu446Ile/c.1336T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),2724,33,2766,"0,0119305857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,215,Tolerated,"33,14","19,36"
"low freq, many artifacts",UPN2_044,4,106156448,A,G,missense_variant(MODERATE|MISSENSE|aAa/aGa|p.Lys450Arg/c.1349A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),5510,62,5588,"0,011095204",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,"0,011",Damaging,"33,72","33,06"
"low freq, many artifacts",UPN2_044,4,106156451,T,C,missense_variant(MODERATE|MISSENSE|aTa/aCa|p.Ile451Thr/c.1352T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),5488,74,5587,"0,0132450331",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,"0,385",Tolerated,"34,13","35,09"
"low freq, many artifacts",UPN2_056,4,106156477,T,A,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser460Thr/c.1378T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),4526,59,4599,"0,0128288758",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,"0,013",Damaging,"33,06","26,2"
"low freq, many artifacts",UPN2_044,4,106156510,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser471Arg/c.1411A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),5287,64,5381,"0,0118937001",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,4",Neutral,12,Damaging,"35,45","35,5"
"low freq, many artifacts",UPN2_044,4,106156551,T,G,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys484Trp/c.1452T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),5285,59,5381,"0,0109645047",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,44",Neutral,"0,01",Damaging,"35,2","35,41"
"low freq, many artifacts",UPN2_044,4,106156553,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val485Gly/c.1454T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),5260,86,5381,"0,0159821594",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,"0,127",Tolerated,"35,26","35,02"
"low bq, low freq, many artifacts, many samples",UPN2_041,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),15881,258,16177,"0,015948569",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"31,35","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_089,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),31515,322,31865,"0,010105131",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,62","15,49"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),65921,854,66893,"0,0127666572",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"32,38","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),43644,505,44225,"0,0114188807",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"32,67","15,4"
"low bq, low freq, many artifacts, many samples",UPN2_045,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),58919,688,59714,"0,0115215862",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"32,68","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_046,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),52308,537,52901,"0,0101510368",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"32,7","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),71539,877,72540,"0,0120898814",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"32,45","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_048,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),37026,532,37622,"0,0141406624",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"31,64","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),41662,541,42291,"0,0127923199",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"32,54","16,03"
"low bq, low freq, many artifacts, many samples",UPN2_050,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),54648,664,55403,"0,0119849106",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"32,67","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),41519,473,42046,"0,0112495838",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"32,87","15,51"
"low bq, low freq, many artifacts, many samples",UPN2_052,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),44357,454,44862,"0,0101199233",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"32,85","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_053,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),57409,657,58159,"0,0112966179",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"32,79","16,06"
"low bq, low freq, many artifacts, many samples",UPN2_054,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),40820,430,41311,"0,0104088499",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"32,81","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_010,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),57670,588,58331,"0,0100804032",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,58","16,01"
"low bq, low freq, many artifacts, many samples",UPN2_055,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),61925,729,62754,"0,0116167894",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"32,76","15,37"
"low bq, low freq, many artifacts, many samples",UPN2_056,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),17921,242,18189,"0,0133047446",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"32,15","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_090,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),26966,354,27348,"0,0129442738",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,64","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_057,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),57068,668,57877,"0,0115417178",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"32,55","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_058,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),54348,640,55069,"0,0116217836",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"32,75","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_059,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),60249,882,61240,"0,0144023514",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"32,85","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_060,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),39068,550,39687,"0,0138584423",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,09","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_091,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),22819,245,23097,"0,0106074382",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,61","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_092,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),17883,192,18098,"0,0106089071",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,59","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_093,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),18991,238,19241,"0,0123694195",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,66","17,28"
"low bq, low freq, many artifacts, many samples",UPN2_061,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),34725,405,35227,"0,0114968632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,31","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_062,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),28089,336,28518,"0,0117820324",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,17","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_063,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),36152,427,36659,"0,01164789",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,17","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_064,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),35658,432,36146,"0,0119515299",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,06","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_065,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),44146,605,44824,"0,0134972336",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,02","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_066,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),71449,1031,72598,"0,0142014932",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,05","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_067,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),76246,1004,77391,"0,0129730847",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,17","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_068,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),46879,569,47504,"0,0119779387",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,28","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_069,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),45997,596,46679,"0,0127680542",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,25","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_070,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),30836,341,31235,"0,0109172403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,23","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_071,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),24462,358,24862,"0,0143994852",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"32,91","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),27488,400,27942,"0,0143153675",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,06","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),27886,363,28290,"0,0128313892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,14","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_074,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),32132,419,32608,"0,0128496075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,17","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_075,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),39846,490,40399,"0,0121290131",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,19","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_076,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),40997,500,41571,"0,0120276154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,26","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_077,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),44396,547,45021,"0,0121498856",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,27","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_078,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),35303,450,35816,"0,0125642171",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,22","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_079,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),22592,296,22949,"0,0128981655",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,19","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_080,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),35390,478,35942,"0,0132992043",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"32,99","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),45397,679,46169,"0,0147068379",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"32,95","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_082,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),65345,919,66417,"0,0138368189",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,09","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_083,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),47352,560,47975,"0,0116727462",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,35","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_084,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),58707,694,59517,"0,011660534",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,2","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_085,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),62760,832,63742,"0,0130526184",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,03","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_086,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),49419,642,50134,"0,0128056808",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,1","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_087,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),59530,763,60412,"0,0126299411",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,17","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_088,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),43004,558,43638,"0,0127870205",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,27","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_095,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),30780,341,31159,"0,0109438685",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,66","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_097,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),29302,317,29645,"0,0106932029",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,64","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_098,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),30204,349,30577,"0,0114138078",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,55","15,91"
"low bq, low freq, many artifacts, many samples",UPN2_099,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),17115,177,17307,"0,0102270757",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,66","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_100,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),29729,326,30094,"0,0108327241",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,71","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_102,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),34002,367,34408,"0,0106661242",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,66","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_104,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),36480,410,36938,"0,0110996805",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,66","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_106,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),45182,560,45784,"0,0122313472",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,45","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_107,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),58090,734,58894,"0,0124630692",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,53","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_108,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),44938,506,45490,"0,0111233238",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,68","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_110,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),48562,494,49136,"0,0100537284",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,6","14,83"
"low bq, low freq, many artifacts",UPN2_111,4,106156560,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg487Ser/c.1461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),39486,430,39957,"0,0107615687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,66,Tolerated,"33,61","14,68"
"low freq, many artifacts",UPN2_044,4,106156571,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln491Leu/c.1472A>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),7686,101,7818,"0,0129189051",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,-1,Neutral,"0,073",Tolerated,"32,96","32,16"
"low freq, many artifacts",UPN2_044,4,106156579,G,T,missense_variant(MODERATE|MISSENSE|Ggg/Tgg|p.Gly494Trp/c.1480G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),4986,54,5052,"0,0106888361",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,33,Damaging,"33,15","30,48"
"low freq, many artifacts",UPN2_044,4,106156583,C,G,missense_variant(MODERATE|MISSENSE|aCa/aGa|p.Thr495Arg/c.1484C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),4963,72,5056,"0,0142405063",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,"0,003",Damaging,"32,93","33,71"
"low freq, many artifacts",UPN2_044,4,106156609,A,G,missense_variant(MODERATE|MISSENSE|Aaa/Gaa|p.Lys504Glu/c.1510A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),4956,95,5063,"0,0187635789",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,68",Neutral,"0,282",Tolerated,"34,44","33,61"
"low freq, many artifacts",UPN2_017,4,106156612,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr505Pro/c.1513A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),12617,140,12826,"0,0109153282",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,05",Neutral,"0,012",Damaging,"34,83","33,6"
"low freq, many artifacts",UPN2_044,4,106156612,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr505Pro/c.1513A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),4974,54,5063,"0,0106656133",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,05",Neutral,"0,012",Damaging,"34,12","31,74"
"inspected, strandbias",UPN2_044,4,106156680,C,A,missense_variant(MODERATE|MISSENSE|gaC/gaA|p.Asp527Glu/c.1581C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),4455,111,4579,"0,0242411007",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,2",Neutral,"0,534",Tolerated,"35,12","34,63"
"low freq, many artifacts",UPN2_029,4,106156701,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg534Ser/c.1602A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),21361,225,21784,"0,0103286816",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,21",Neutral,"0,037",Damaging,"35,5","35,52"
"low freq, many artifacts",UPN2_004,4,106156702,A,C,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn535His/c.1603A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),3156,34,3217,"0,010568853",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,75",Neutral,1,Tolerated,"35,21","35,35"
many samples,UPN2_001,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),12102,273,12397,"0,0220214568",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,101,Tolerated,"32,53","31,49"
"low freq, many artifacts, many samples",UPN2_014,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),17286,353,17688,"0,019957033",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,"0,101",Tolerated,"32,59","31,33"
"low freq, many artifacts, many samples",UPN2_015,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),23181,284,23536,"0,0120666213",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,101,Tolerated,"32,65","31,26"
"low freq, many artifacts, many samples",UPN2_016,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),11155,183,11366,"0,0161006511",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,101,Tolerated,"32,66","31,03"
"low freq, many artifacts, many samples",UPN2_017,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),8232,173,8428,"0,0205268154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,101,Tolerated,"32,72","31,62"
"low freq, many artifacts, many samples",UPN2_018,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),11428,174,11624,"0,0149690296",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,101,Tolerated,"32,7","31,54"
"low freq, many artifacts, many samples",UPN2_019,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),13315,230,13579,"0,0169379188",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,"0,101",Tolerated,"32,69","31,73"
"low freq, many artifacts, many samples",UPN2_020,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),11430,198,11661,"0,0169796758",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,101,Tolerated,"32,64","31,54"
many samples,UPN2_021,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),11910,270,12200,"0,0221311475",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,101,Tolerated,"32,64","31,53"
"low freq, many artifacts, many samples",UPN2_002,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),14342,401,14768,"0,0271533044",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,"0,101",Tolerated,"32,61","31,22"
many samples,UPN2_003,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),3082,74,3158,"0,0234325522",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,101,Tolerated,"32,61","31,76"
"low freq, many artifacts, many samples",UPN2_022,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),18699,253,18996,"0,0133185934",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,101,Tolerated,"32,71","31,08"
"low freq, many artifacts, many samples",UPN2_023,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),20372,312,20723,"0,0150557352",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,"0,101",Tolerated,"32,68","31,55"
"low freq, many artifacts, many samples",UPN2_024,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),10144,122,10292,"0,0118538671",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,101,Tolerated,"32,68","30,99"
"low freq, many artifacts, many samples",UPN2_025,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),19439,275,19755,"0,0139205264",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,101,Tolerated,"32,64","31,55"
"low freq, many artifacts, many samples",UPN2_026,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),21782,357,22191,"0,0160876031",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,101,Tolerated,"32,69","31,49"
many samples,UPN2_004,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),3065,114,3189,"0,0357478833",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,101,Tolerated,"32,29","31,45"
"low freq, many artifacts, many samples",UPN2_027,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),22559,378,22983,"0,016446939",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,101,Tolerated,"32,68","31,46"
"low freq, many artifacts, many samples",UPN2_028,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),15718,307,16051,"0,0191265342",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,101,Tolerated,"32,52","31,61"
"low freq, many artifacts, many samples",UPN2_029,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),21135,436,21606,"0,0201795797",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,101,Tolerated,"32,62","31,58"
"low freq, many artifacts, many samples",UPN2_030,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),18131,281,18456,"0,015225401",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,101,Tolerated,"32,65","31,38"
"low freq, many artifacts, many samples",UPN2_031,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),11872,162,12071,"0,0134205948",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,101,Tolerated,"32,71","31,53"
many samples,UPN2_005,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),4216,128,4350,"0,0294252874",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,101,Tolerated,"32,54","31,41"
"low freq, many artifacts, many samples",UPN2_032,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),7573,119,7720,"0,0154145078",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,101,Tolerated,"32,68","31,06"
"low freq, many artifacts, many samples",UPN2_046,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),25165,286,25494,"0,0112183259",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,"0,101",Tolerated,"32,47","31,06"
"low freq, many artifacts, many samples",UPN2_033,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),14439,212,14695,"0,0144266757",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,"0,101",Tolerated,"32,69","31,6"
"low freq, many artifacts, many samples",UPN2_034,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),5758,77,5850,"0,0131623932",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,101,Tolerated,"32,66","31,86"
"low freq, many artifacts, many samples",UPN2_035,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),30941,627,31654,"0,0198079232",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,"0,101",Tolerated,"32,68","31,4"
"low freq, many artifacts, many samples",UPN2_036,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),32348,692,33113,"0,0208981367",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,101,Tolerated,"32,58","31,67"
many samples,UPN2_006,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),16561,513,17088,"0,0300210674",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,101,Tolerated,"32,61","31,56"
"low freq, many artifacts, many samples",UPN2_037,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),23203,367,23635,"0,0155278189",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,"0,101",Tolerated,"32,67","31,57"
"low freq, many artifacts, many samples",UPN2_038,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),30805,559,31441,"0,0177793327",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,101,Tolerated,"32,65","31,6"
"low freq, many artifacts, many samples",UPN2_039,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),27371,511,27928,"0,0182970496",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,"0,101",Tolerated,"32,65","31,67"
"low freq, many artifacts, many samples",UPN2_007,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),33576,720,34361,"0,0209539885",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,101,Tolerated,"32,55","31,27"
"low freq, many artifacts, many samples",UPN2_008,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),42188,807,43094,"0,0187265048",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,101,Tolerated,"32,52","31,41"
"low freq, many artifacts, many samples",UPN2_009,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),36480,637,37213,"0,0171176739",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,"0,101",Tolerated,"32,43","31,41"
"low freq, many artifacts, many samples",UPN2_010,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),26620,539,27253,"0,0197776392",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,101,Tolerated,"32,52","31,53"
many samples,UPN2_011,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),32344,761,33189,"0,0229292838",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,101,Tolerated,"32,47","31,48"
"low freq, many artifacts, many samples",UPN2_058,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),25929,336,26328,"0,0127620784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,101,Tolerated,"32,49","31,43"
"low freq, many artifacts, many samples",UPN2_059,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),40479,626,41193,"0,0151967567",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,"0,101",Tolerated,"32,69","31,12"
many samples,UPN2_012,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),15711,360,16129,"0,0223200446",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,101,Tolerated,"32,56","31,65"
"low freq, many artifacts, many samples",UPN2_060,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),24766,477,25349,"0,0188173103",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,"0,101",Tolerated,"32,79","31,01"
"low freq, many artifacts, many samples",UPN2_040,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),39154,695,39985,"0,0173815181",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,"0,101",Tolerated,"32,64","31,49"
"low freq, many artifacts, many samples",UPN2_013,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),8899,179,9095,"0,0196811435",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,"0,101",Tolerated,"32,57","31,66"
"low freq, many artifacts, many samples",UPN2_061,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),21797,419,22261,"0,0188221553",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,101,Tolerated,"32,96","31,19"
"low freq, many artifacts, many samples",UPN2_062,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),20052,413,20506,"0,0201404467",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,101,Tolerated,"33,02","30,74"
"low freq, many artifacts, many samples",UPN2_063,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),22747,547,23351,"0,023425121",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,"0,101",Tolerated,"32,87","31,09"
"low freq, many artifacts, many samples",UPN2_064,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),25076,538,25662,"0,0209648508",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,"0,101",Tolerated,"32,94","31,02"
"low freq, many artifacts, many samples",UPN2_065,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),28380,453,28916,"0,0156660672",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,"0,101",Tolerated,"32,77","31,06"
"low freq, many artifacts, many samples",UPN2_066,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),43556,751,44445,"0,0168972888",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,"0,101",Tolerated,"32,7","31,07"
"low freq, many artifacts, many samples",UPN2_067,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),46388,771,47324,"0,0162919449",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,"0,101",Tolerated,"32,78","31,22"
"low freq, many artifacts, many samples",UPN2_068,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),28677,438,29182,"0,0150092523",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,101,Tolerated,"32,84","31,23"
"low freq, many artifacts, many samples",UPN2_069,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),28822,547,29464,"0,0185650285",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,101,Tolerated,"32,92","31,05"
"low freq, many artifacts, many samples",UPN2_070,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),19496,343,19881,"0,0172526533",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,"0,101",Tolerated,"32,93","30,9"
"low freq, many artifacts, many samples",UPN2_071,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),17108,376,17527,"0,021452616",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,"0,101",Tolerated,"32,88","30,9"
"low freq, many artifacts, many samples",UPN2_072,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),19346,386,19770,"0,0195245321",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,"0,101",Tolerated,"32,96","31,23"
"low freq, many artifacts, many samples",UPN2_073,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),18257,320,18607,"0,0171978288",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,101,Tolerated,"32,86","31,14"
"low freq, many artifacts, many samples",UPN2_074,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),20150,363,20568,"0,0176487748",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,"0,101",Tolerated,"32,8","31,52"
"low freq, many artifacts, many samples",UPN2_075,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),26741,449,27246,"0,0164794832",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,101,Tolerated,"32,94","31,12"
"low freq, many artifacts, many samples",UPN2_076,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),25388,524,25959,"0,0201856774",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,"0,101",Tolerated,"32,84","31,42"
"low freq, many artifacts, many samples",UPN2_077,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),27686,539,28306,"0,0190418992",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,"0,101",Tolerated,"32,9","31,22"
"low freq, many artifacts, many samples",UPN2_078,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),23285,434,23764,"0,0182629187",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,101,Tolerated,"32,91","31,02"
"low freq, many artifacts, many samples",UPN2_079,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),14861,275,15171,"0,0181266891",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,101,Tolerated,"32,96","30,68"
"low freq, many artifacts, many samples",UPN2_080,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),24176,509,24767,"0,0205515404",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,101,Tolerated,"32,91","30,95"
"low freq, many artifacts, many samples",UPN2_081,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),32622,540,33267,"0,0162323023",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,101,Tolerated,"32,95",31
"low freq, many artifacts, many samples",UPN2_082,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),41944,590,42632,"0,0138393695",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,"0,101",Tolerated,"32,8","31,01"
"low freq, many artifacts, many samples",UPN2_083,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),29102,583,29769,"0,0195841311",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,"0,101",Tolerated,"32,92","31,23"
"low freq, many artifacts, many samples",UPN2_084,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),35663,638,36429,"0,0175135194",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,"0,101",Tolerated,"32,82",31
"low freq, many artifacts, many samples",UPN2_085,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),39387,646,40131,"0,0160972814",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,"0,101",Tolerated,"32,73",31
"low freq, many artifacts, many samples",UPN2_086,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),31577,527,32180,"0,0163766314",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,"0,101",Tolerated,"32,76","30,94"
"low freq, many artifacts",UPN2_087,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),38116,636,38877,"0,016359287",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,101,Tolerated,"32,91","31,12"
"low freq, many artifacts, many samples",UPN2_088,4,106156710,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu537Asp/c.1611G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),26108,515,26710,"0,0192811681",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,"0,101",Tolerated,"32,87","31,2"
"low freq, many artifacts",UPN2_006,4,106156714,G,A,missense_variant(MODERATE|MISSENSE|Gag/Aag|p.Glu539Lys/c.1615G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),4235,47,4292,"0,0109506058",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,17",Neutral,"0,078",Tolerated,"35,3","33,34"
"low freq, many artifacts",UPN2_041,4,106156721,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu541Gln/c.1622T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),3244,60,3328,"0,0180288462",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,"0,066",Tolerated,"34,36","30,15"
"low freq, many artifacts",UPN2_048,4,106156721,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu541Gln/c.1622T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),6295,91,6416,"0,0141832918",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,"0,066",Tolerated,"34,53","29,53"
"low freq, many artifacts",UPN2_005,4,106156734,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp545Glu/c.1635C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),1889,20,1913,"0,0104547831",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,"0,703",Tolerated,"34,43","34,35"
inspected,UPN2_042,4,106156747,C,T,stop_gained(HIGH|NONSENSE|Cga/Tga|p.Arg550*/c.1648C>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),18784,830,19659,"0,0422198484",0,0,0,0,1,1,0,1,3,NO,NO,"COSM41644, COSM1318629",haematopoietic_and_lymphoid_tissue,33,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,29","34,43"
"low freq, many artifacts",UPN2_044,4,106156756,G,A,missense_variant(MODERATE|MISSENSE|Gtg/Atg|p.Val553Met/c.1657G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),4074,71,4164,"0,0170509126",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,31",Neutral,"0,153",Tolerated,"32,59","33,7"
"low bq, low freq, many artifacts",UPN2_046,4,106156757,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val553Glu/c.1658T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),12817,137,13031,"0,0105133911",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,46,Damaging,"30,83","21,15"
"low freq, many artifacts",UPN2_048,4,106156758,GC,G,frameshift_variant(HIGH||cca/|p.Pro555fs/c.1664delC|2002|TET2|protein_coding|CODING|ENST00000380013|3|G|INFO_REALIGN_3_PRIME),12686,136,12929,"0,0105189883",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,41",NA
"low freq, many artifacts",UPN2_041,4,106156765,AC,A,frameshift_variant(HIGH||aca/|p.Thr556fs/c.1667delC|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),6309,70,6447,"0,0108577633",0,0,0,1,1,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,14",NA
"low freq, many artifacts",UPN2_041,4,106156772,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His558Leu/c.1673A>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),6349,69,6447,"0,0107026524",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,57",Neutral,"0,189",Tolerated,"33,38","30,16"
"low bq, low freq, many artifacts",UPN2_050,4,106156776,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr559*/c.1677T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),15025,154,15249,"0,0100990229",0,0,0,0,1,0,0,0,1,NO,NO,COSM4383820. COSM4383821,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,57","22,76"
"low freq, many artifacts",UPN2_041,4,106156778,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu560Gln/c.1679T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),6293,106,6443,"0,0164519634",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,88",Neutral,"0,008",Damaging,"33,71","26,75"
"low freq, many artifacts",UPN2_044,4,106156879,C,T,missense_variant(MODERATE|MISSENSE|Ccc/Tcc|p.Pro594Ser/c.1780C>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),10869,180,11101,"0,0162147554",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,9",Neutral,1,Tolerated,"31,89","32,28"
"low freq, many artifacts",UPN2_041,4,106156882,A,T,missense_variant(MODERATE|MISSENSE|Aat/Tat|p.Asn595Tyr/c.1783A>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),20027,307,20419,"0,0150350164",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,58",Deleterious,"0,004",Damaging,"32,74",28
"low freq, many artifacts",UPN2_044,4,106156913,A,T,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr605Phe/c.1814A>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),8768,93,8874,"0,0104800541",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,24,Damaging,"34,34","30,06"
"low freq, many artifacts",UPN2_044,4,106156932,G,C,missense_variant(MODERATE|MISSENSE|atG/atC|p.Met611Ile/c.1833G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),8701,125,8875,"0,014084507",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,71",Neutral,"0,266",Tolerated,"32,75","31,15"
"low freq, many artifacts",UPN2_041,4,106156932,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met611Ile/c.1833G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),20133,274,20459,"0,0133926389",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,71",Neutral,"0,266",Tolerated,"32,86","28,11"
"many samples, ins and del, low freq",UPN2_035,4,106156935,T,TG,frameshift_variant(HIGH||ctc/Gctc|p.Leu615fs/c.1842dupG|2002|TET2|protein_coding|CODING|ENST00000380013|3|TG|INFO_REALIGN_3_PRIME),50376,704,50864,"0,0138408304",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,47",NA
"many samples, ins and del, low freq",UPN2_036,4,106156935,T,TG,frameshift_variant(HIGH||ctc/Gctc|p.Leu615fs/c.1842dupG|2002|TET2|protein_coding|CODING|ENST00000380013|3|TG|INFO_REALIGN_3_PRIME),42002,630,42464,"0,0148360965",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,48",NA
"many samples, ins and del, low freq",UPN2_039,4,106156935,T,TG,frameshift_variant(HIGH||ctc/Gctc|p.Leu615fs/c.1842dupG|2002|TET2|protein_coding|CODING|ENST00000380013|3|TG|INFO_REALIGN_3_PRIME),44494,982,44978,"0,0218328961",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,53",NA
"many samples, ins and del, low freq",UPN2_040,4,106156935,T,TG,frameshift_variant(HIGH||ctc/Gctc|p.Leu615fs/c.1842dupG|2002|TET2|protein_coding|CODING|ENST00000380013|3|TG|INFO_REALIGN_3_PRIME),53302,918,53820,"0,0170568562",1,0,0,1,0,0,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,47",NA
"many samples, ins and del, low freq",UPN2_001,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),23033,280,23441,"0,0119448829",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,67",NA
"many samples, ins and del, low freq",UPN2_014,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),28532,346,28990,"0,0119351501",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,5",NA
"many samples, ins and del, low freq",UPN2_015,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),41588,469,42214,"0,0111100583",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,51",NA
"many samples, ins and del, low freq",UPN2_016,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),20021,290,20400,"0,0142156863",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,53",NA
"many samples, ins and del, low freq",UPN2_017,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),14332,171,14547,"0,011755001",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,61",NA
"many samples, ins and del, low freq",UPN2_018,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),21952,299,22309,"0,0134026626",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,59",NA
"many samples, ins and del, low freq",UPN2_019,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),24712,302,25083,"0,0120400271",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,54",NA
"many samples, ins and del, low freq",UPN2_020,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),18253,224,18531,"0,0120878528",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,51",NA
"many samples, ins and del, low freq",UPN2_021,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),21639,266,21973,"0,0121057662",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,58",NA
"many samples, ins and del, low freq",UPN2_003,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),5829,70,5918,"0,0118283204",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,6",NA
"many samples, ins and del, low freq",UPN2_022,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),32036,382,32526,"0,0117444506",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,55",NA
"many samples, ins and del, low freq",UPN2_023,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),33616,421,34150,"0,0123279649",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,46",NA
"many samples, ins and del, low freq",UPN2_041,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),19983,283,20466,"0,013827812",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,54",NA
"many samples, ins and del, low freq",UPN2_024,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),16986,246,17321,"0,0142024133",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,54",NA
"many samples, ins and del, low freq",UPN2_025,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),35720,445,36275,"0,0122674018",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,55",NA
"many samples, ins and del, low freq",UPN2_026,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),37061,390,37559,"0,010383663",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,63",NA
"many samples, ins and del, low freq",UPN2_004,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),7097,109,7224,"0,0150885936",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,63",NA
"many samples, ins and del, low freq",UPN2_027,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),39645,506,40317,"0,012550537",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,56",NA
"many samples, ins and del, low freq",UPN2_089,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),26269,421,26784,"0,0157183393",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,27",NA
"many samples, ins and del, low freq",UPN2_042,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),64478,831,65693,"0,0126497496",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,49",NA
"many samples, ins and del, low freq",UPN2_028,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),29671,367,30159,"0,0121688385",1,0,0,1,0,0,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,52",NA
"many samples, ins and del, low freq",UPN2_043,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),40573,689,41476,"0,0166120166",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,5",NA
"many samples, ins and del, low freq",UPN2_044,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),8729,122,8881,"0,0137371918",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,44",NA
"many samples, ins and del, low freq",UPN2_029,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),34101,363,34635,"0,0104807276",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,51",NA
"many samples, ins and del, low freq",UPN2_030,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),32403,395,32914,"0,0120009722",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,6",NA
"many samples, ins and del, low freq",UPN2_005,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),8569,108,8701,"0,0124123664",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,67",NA
"many samples, ins and del, low freq",UPN2_045,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),50862,715,51823,"0,0137969627",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,52",NA
"many samples, ins and del, low freq",UPN2_032,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),11658,161,11877,"0,0135556117",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,52",NA
"many samples, ins and del, low freq",UPN2_046,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),45046,622,45886,"0,0135553328",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,34",NA
"many samples, ins and del, low freq",UPN2_033,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),25669,290,26048,"0,0111332924",1,0,0,1,0,0,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,52",NA
"many samples, ins and del, low freq",UPN2_034,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),9794,127,9967,"0,0127420488",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,6",NA
"many samples, ins and del, low freq",UPN2_047,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),69199,992,70538,"0,0140633417",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,48",NA
"many samples, ins and del, low freq",UPN2_048,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),41778,578,42562,"0,0135801889",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,53",NA
"many samples, ins and del, low freq",UPN2_035,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),49975,641,50866,"0,0126017379",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,54",NA
"many samples, ins and del, low freq",UPN2_036,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),41782,530,42465,"0,0124808666",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,48",NA
"many samples, ins and del, low freq",UPN2_006,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),38703,517,39391,"0,0131248255",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,69",NA
"many samples, ins and del, low freq",UPN2_049,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),39960,622,40783,"0,0152514528",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,52",NA
"many samples, ins and del, low freq",UPN2_050,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),43031,661,43916,"0,0150514619",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,57",NA
"many samples, ins and del, low freq",UPN2_037,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),41275,517,41911,"0,0123356637",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,67",NA
"many samples, ins and del, low freq",UPN2_051,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),36982,556,37745,"0,0147304279",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,63",NA
"many samples, ins and del, low freq",UPN2_052,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),37044,441,37690,"0,0117007164",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,59",NA
"many samples, ins and del, low freq",UPN2_038,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),55346,787,56328,"0,013971737",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,54",NA
"many samples, ins and del, low freq",UPN2_039,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),44108,678,44984,"0,0150720256",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,54",NA
"many samples, ins and del, low freq",UPN2_053,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),51643,735,52716,"0,013942636",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,56",NA
"many samples, ins and del, low freq",UPN2_054,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),35138,507,35856,"0,0141398929",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,4",NA
"low freq, many artifacts, many samples",UPN2_007,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),68885,699,69873,"0,0100038642",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,63",NA
"many samples, ins and del, low freq",UPN2_008,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),83900,888,85081,"0,0104371129",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,7",NA
"many samples, ins and del, low freq",UPN2_009,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),67083,744,68089,"0,0109268751",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,65",NA
"many samples, ins and del, low freq",UPN2_055,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),55861,889,57076,"0,0155757236",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,53",NA
"many samples, ins and del, low freq",UPN2_056,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),17892,374,18415,"0,0203095303",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,52",NA
"many samples, ins and del, low freq",UPN2_090,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),20269,223,20577,"0,0108373427",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,24",NA
"many samples, ins and del, low freq",UPN2_057,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),47486,731,48497,"0,0150730973",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,49",NA
"many samples, ins and del, low freq",UPN2_058,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),43573,585,44343,"0,0131926121",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,45",NA
"many samples, ins and del, low freq",UPN2_059,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),72048,885,73469,"0,0120458969",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"30,9",NA
"many samples, ins and del, low freq",UPN2_012,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),31462,365,31920,"0,0114348371",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,6",NA
"many samples, ins and del, low freq",UPN2_060,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),56289,675,57407,"0,011758148",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"30,89",NA
"many samples, ins and del, low freq",UPN2_013,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),18468,245,18802,"0,0130305287",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,57",NA
"many samples, ins and del, low freq",UPN2_091,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),19039,221,19331,"0,0114324143",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,23",NA
"many samples, ins and del, low freq",UPN2_092,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),13401,181,13646,"0,0132639601",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,28",NA
"many samples, ins and del, low freq",UPN2_093,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),14689,217,14975,"0,014490818",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,24",NA
"many samples, ins and del, low freq",UPN2_061,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),42744,508,43563,"0,0116612722",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"30,98",NA
"many samples, ins and del, low freq",UPN2_062,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),36974,424,37750,"0,0112317881",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"30,81",NA
"many samples, ins and del, low freq",UPN2_063,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),47573,503,48430,"0,0103861243",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"30,91",NA
"many samples, ins and del, low freq",UPN2_064,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),49832,606,50817,"0,0119251432",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"30,9",NA
"many samples, ins and del, low freq",UPN2_065,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),52905,651,53927,"0,0120718749",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"30,83",NA
"many samples, ins and del, low freq",UPN2_066,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),76508,927,78041,"0,0118783716",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"30,91",NA
"many samples, ins and del, low freq",UPN2_067,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),74924,909,76426,"0,0118938581",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"30,82",NA
"many samples, ins and del, low freq",UPN2_068,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),53358,650,54376,"0,0119538031",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"30,95",NA
"many samples, ins and del, low freq",UPN2_069,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),62244,687,63427,"0,0108313494",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"30,93",NA
"many samples, ins and del, low freq",UPN2_070,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),40039,474,40881,"0,0115946283",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"30,78",NA
"many samples, ins and del, low freq",UPN2_071,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),37974,434,38674,"0,0112220096",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"30,9",NA
"many samples, ins and del, low freq",UPN2_072,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),43332,506,44168,"0,0114562579",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"30,84",NA
"low freq, many artifacts, many samples",UPN2_073,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),42202,430,42954,"0,0100107091",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"30,95",NA
"many samples, ins and del, low freq",UPN2_075,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),57931,673,59072,"0,0113928765",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"30,83",NA
"many samples, ins and del, low freq",UPN2_076,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),52352,676,53446,"0,0126482805",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"30,97",NA
"many samples, ins and del, low freq",UPN2_077,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),52857,618,53896,"0,0114665281",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"30,94",NA
"many samples, ins and del, low freq",UPN2_078,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),49378,566,50331,"0,0112455544",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"30,74",NA
"many samples, ins and del, low freq",UPN2_079,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),31040,394,31674,"0,0124392246",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"30,86",NA
"many samples, ins and del, low freq",UPN2_080,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),51473,612,52478,"0,0116620298",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"30,9",NA
"many samples, ins and del, low freq",UPN2_081,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),66348,722,67593,"0,0106815795",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"30,81",NA
"many samples, ins and del, low freq",UPN2_082,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),72352,872,73778,"0,0118192415",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"30,83",NA
"many samples, ins and del, low freq",UPN2_083,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),63229,732,64384,"0,0113692843",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,01",NA
"many samples, ins and del, low freq",UPN2_084,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),65597,755,66887,"0,0112876942",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"30,9",NA
"many samples, ins and del, low freq",UPN2_085,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),53562,617,54625,"0,0112951945",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"30,88",NA
"many samples, ins and del, low freq",UPN2_086,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),42269,521,43186,"0,0120640948",1,0,0,1,0,0,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"30,74",NA
"many samples, ins and del, low freq",UPN2_087,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),72484,844,73937,"0,0114151237",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"30,84",NA
"many samples, ins and del, low freq",UPN2_088,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),55199,656,56232,"0,0116659553",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"30,8",NA
"many samples, ins and del, low freq",UPN2_094,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),27011,347,27495,"0,0126204765",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,27",NA
"many samples, ins and del, low freq",UPN2_095,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),26343,296,26837,"0,0110295488",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"30,92",NA
"many samples, ins and del, low freq",UPN2_096,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),28300,335,28749,"0,0116525792",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,22",NA
"many samples, ins and del, low freq",UPN2_097,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),25395,303,25788,"0,011749651",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,22",NA
"many samples, ins and del, low freq",UPN2_098,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),25182,342,25646,"0,0133354129",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,22",NA
"many samples, ins and del, low freq",UPN2_099,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),13870,160,14095,"0,0113515431",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,3",NA
"many samples, ins and del, low freq",UPN2_100,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),24224,348,24689,"0,0140953461",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,36",NA
"many samples, ins and del, low freq",UPN2_101,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),23719,296,24131,"0,0122663793",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,32",NA
"many samples, ins and del, low freq",UPN2_102,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),27841,403,28362,"0,0142091531",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,28",NA
"many samples, ins and del, low freq",UPN2_103,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),26898,339,27370,"0,0123858239",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"30,98",NA
"many samples, ins and del, low freq",UPN2_104,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),31700,373,32199,"0,0115842107",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,29",NA
"many samples, ins and del, low freq",UPN2_105,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),26438,293,26831,"0,0109202042",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,27",NA
"many samples, ins and del, low freq",UPN2_106,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),41620,526,42365,"0,0124159094",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,16",NA
"many samples, ins and del, low freq",UPN2_107,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),47326,535,48061,"0,0111316868",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,27",NA
"many samples, ins and del, low freq",UPN2_108,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),36441,422,37001,"0,0114050972",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,24",NA
"many samples, ins and del, low freq",UPN2_109,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),40020,496,40693,"0,0121888285",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,25",NA
"many samples, ins and del, low freq",UPN2_110,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),39763,436,40351,"0,0108051845",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"31,21",NA
"many samples, ins and del, low freq",UPN2_111,4,106156935,TG,T,frameshift_variant(HIGH||ggg/|p.Leu615fs/c.1842delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),32990,446,33606,"0,0132714396",1,0,0,1,0,0,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"30,93",NA
"low freq, many artifacts",UPN2_044,4,106156940,G,A,missense_variant(MODERATE|MISSENSE|gGg/gAg|p.Gly614Glu/c.1841G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),8706,151,8880,"0,0170045045",0,0,0,0,0,1,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,"0,065",Tolerated,"33,15","33,89"
"low freq, many artifacts",UPN2_044,4,106156960,A,G,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr621Ala/c.1861A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),4317,55,4406,"0,0124829778",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,"0,047",Damaging,"34,83","35,36"
"low freq, many samples",UPN2_016,4,106156986,C,A,missense_variant(MODERATE|MISSENSE|caC/caA|p.His629Gln/c.1887C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),21903,252,22201,"0,0113508401",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,05",Neutral,1,Tolerated,"35,37","34,51"
"low freq, many samples",UPN2_032,4,106156986,C,A,missense_variant(MODERATE|MISSENSE|caC/caA|p.His629Gln/c.1887C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),13788,147,13972,"0,0105210421",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,05",Neutral,1,Tolerated,"35,43","34,05"
"low freq, many artifacts, many samples",UPN2_047,4,106156986,C,A,missense_variant(MODERATE|MISSENSE|caC/caA|p.His629Gln/c.1887C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),80323,841,81382,"0,0103339805",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,05",Neutral,1,Tolerated,"34,96","33,46"
"low freq, many artifacts, many samples",UPN2_048,4,106156986,C,A,missense_variant(MODERATE|MISSENSE|caC/caA|p.His629Gln/c.1887C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),48813,506,49431,"0,0102364913",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,05",Neutral,1,Tolerated,35,"33,31"
"low freq, many samples",UPN2_035,4,106156986,C,A,missense_variant(MODERATE|MISSENSE|caC/caA|p.His629Gln/c.1887C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),57819,674,58633,"0,0114952331",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,05",Neutral,1,Tolerated,"35,4","34,6"
"low freq, many samples",UPN2_036,4,106156986,C,A,missense_variant(MODERATE|MISSENSE|caC/caA|p.His629Gln/c.1887C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),50858,638,51592,"0,0123662583",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,05",Neutral,1,Tolerated,"35,41","34,68"
"low freq, many samples",UPN2_006,4,106156986,C,A,missense_variant(MODERATE|MISSENSE|caC/caA|p.His629Gln/c.1887C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),42833,546,43497,"0,0125525898",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,05",Neutral,1,Tolerated,"35,23","34,26"
"low freq, many samples",UPN2_049,4,106156986,C,A,missense_variant(MODERATE|MISSENSE|caC/caA|p.His629Gln/c.1887C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),44225,548,44885,"0,0122089785",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,05",Neutral,1,Tolerated,"34,93","33,4"
"low freq, many artifacts, many samples",UPN2_050,4,106156986,C,A,missense_variant(MODERATE|MISSENSE|caC/caA|p.His629Gln/c.1887C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),50976,553,51689,"0,0106986012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,05",Neutral,1,Tolerated,"34,97","32,84"
"low freq, many samples",UPN2_039,4,106156986,C,A,missense_variant(MODERATE|MISSENSE|caC/caA|p.His629Gln/c.1887C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),49382,550,50020,"0,0109956018",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,05",Neutral,1,Tolerated,"35,38","34,96"
"low freq, many artifacts, many samples",UPN2_053,4,106156986,C,A,missense_variant(MODERATE|MISSENSE|caC/caA|p.His629Gln/c.1887C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),56730,615,57486,"0,010698257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,05",Neutral,1,Tolerated,"34,94",33
"low freq, many samples",UPN2_055,4,106156986,C,A,missense_variant(MODERATE|MISSENSE|caC/caA|p.His629Gln/c.1887C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),61320,691,62171,"0,0111145068",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,05",Neutral,1,Tolerated,"34,92","33,01"
"low freq, many samples",UPN2_056,4,106156986,C,A,missense_variant(MODERATE|MISSENSE|caC/caA|p.His629Gln/c.1887C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),21508,273,21833,"0,0125040077",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,05",Neutral,1,Tolerated,"34,98","33,36"
"low freq, many samples",UPN2_058,4,106156986,C,A,missense_variant(MODERATE|MISSENSE|caC/caA|p.His629Gln/c.1887C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),47740,585,48430,"0,0120792897",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,05",Neutral,1,Tolerated,"34,93","33,29"
"low freq, many artifacts, many samples",UPN2_093,4,106156986,C,A,missense_variant(MODERATE|MISSENSE|caC/caA|p.His629Gln/c.1887C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),16914,177,17141,"0,0103261187",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,05",Neutral,1,Tolerated,"35,39","33,78"
"low freq, many artifacts",UPN2_095,4,106156986,C,A,missense_variant(MODERATE|MISSENSE|caC/caA|p.His629Gln/c.1887C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),28227,290,28571,"0,0101501523",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,05",Neutral,1,Tolerated,"35,32","33,55"
"low freq, many samples",UPN2_097,4,106156986,C,A,missense_variant(MODERATE|MISSENSE|caC/caA|p.His629Gln/c.1887C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),27168,289,27504,"0,0105075625",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,05",Neutral,1,Tolerated,"35,3","34,63"
"low freq, many samples",UPN2_111,4,106156986,C,A,missense_variant(MODERATE|MISSENSE|caC/caA|p.His629Gln/c.1887C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),35531,397,36005,"0,0110262464",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,05",Neutral,1,Tolerated,"35,32","34,21"
many samples,UPN2_001,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),24113,862,25024,"0,0344469309",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,144,Tolerated,"33,39","31,13"
"low freq, many samples",UPN2_014,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),31698,881,32652,"0,0269815019",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"33,63","31,33"
"low freq, many samples",UPN2_015,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),44314,788,45210,"0,0174297722",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"33,58","31,21"
"low freq, many samples",UPN2_016,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),21551,504,22098,"0,0228074939",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"33,53","31,38"
many samples,UPN2_017,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),15763,381,16178,"0,0235505007",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,144,Tolerated,"33,61","31,12"
"low freq, many samples",UPN2_018,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),22975,518,23561,"0,0219854845",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"33,58","31,34"
many samples,UPN2_019,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),25732,743,26541,"0,0279944237",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,144,Tolerated,"33,6","31,51"
many samples,UPN2_020,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),20872,535,21452,"0,0249393996",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,144,Tolerated,"33,67","31,15"
"low freq, many samples",UPN2_021,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),23755,697,24488,"0,0284629206",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"33,65","31,48"
"low freq, many samples",UPN2_002,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),31420,1163,32673,"0,0355951397",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"33,46","31,45"
many samples,UPN2_003,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),6083,175,6272,"0,0279017857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,144,Tolerated,"33,37","31,29"
"low freq, many samples",UPN2_022,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),35833,773,36673,"0,0210781774",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"33,64","31,27"
"low freq, many samples",UPN2_023,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),37768,862,38744,"0,0222486062",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"33,66","31,45"
"low freq, many samples",UPN2_024,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),18407,328,18774,"0,0174709705",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"33,53","31,46"
"low freq, many samples",UPN2_025,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),38077,767,38931,"0,0197015232",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"33,56","31,34"
many samples,UPN2_026,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),40685,927,41707,"0,0222264848",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,144,Tolerated,"33,67","31,53"
many samples,UPN2_004,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),10215,314,10545,"0,0297771456",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,144,Tolerated,"33,86","31,56"
"low freq, many samples",UPN2_027,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),43466,1140,44717,"0,0254936601",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"33,63","31,27"
"low freq, many artifacts, many samples",UPN2_042,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),70167,712,71077,"0,0100173052",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,144,Tolerated,"33,07","29,59"
many samples,UPN2_028,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),32476,822,33384,"0,0246225737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,144,Tolerated,"33,67","31,26"
"low freq, many samples",UPN2_043,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),43932,508,44582,"0,0113947333",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"33,05","29,88"
"low freq, many samples",UPN2_044,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),11798,150,11998,"0,0125020837",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"33,36","28,49"
"low freq, many samples",UPN2_029,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),38168,1007,39259,"0,0256501694",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"33,67","31,19"
"low freq, many samples",UPN2_030,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),35239,841,36147,"0,0232661078",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"33,61","31,15"
"low freq, many samples",UPN2_031,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),23178,443,23666,"0,0187188372",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"33,55","31,41"
many samples,UPN2_005,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),8800,310,9138,"0,0339242723",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,144,Tolerated,"33,43","31,53"
"low freq, many artifacts, many samples",UPN2_032,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),13603,276,13915,"0,0198347107",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,144,Tolerated,"33,66","31,36"
"low freq, many samples",UPN2_046,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),52025,838,53002,"0,0158107241",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"33,22","30,31"
"low freq, many samples",UPN2_033,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),28452,555,29092,"0,0190774096",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"33,61","31,22"
"low freq, many artifacts, many samples",UPN2_034,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),10845,218,11088,"0,0196608947",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,144,Tolerated,"33,61","31,63"
"low freq, many samples",UPN2_047,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),79899,1006,81148,"0,0123971016",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"33,15",30
"low freq, many samples",UPN2_048,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),48431,660,49227,"0,0134072765",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"33,2","30,42"
many samples,UPN2_035,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),56832,1435,58424,"0,0245618239",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,144,Tolerated,"33,69","31,24"
"low freq, many samples",UPN2_036,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),49893,1329,51339,"0,0258867528",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"33,77","31,25"
"low freq, many samples",UPN2_006,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),41536,1690,43322,"0,0390102027",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"33,49","31,47"
"low freq, many samples",UPN2_049,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),44037,524,44705,"0,011721284",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"33,09","30,02"
"low freq, many samples",UPN2_037,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),45317,1013,46422,"0,0218215501",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"33,64","31,31"
"low freq, many samples",UPN2_038,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),61289,1547,62968,"0,0245680346",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"33,66","31,23"
"low freq, many samples",UPN2_039,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),48315,1332,49766,"0,0267652614",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"33,63","31,43"
"low freq, many samples",UPN2_053,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),56331,771,57265,"0,0134637213",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"33,08","30,34"
"low freq, many samples",UPN2_007,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),71562,2283,74026,"0,0308405155",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"33,37","31,1"
"low freq, many samples",UPN2_008,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),86347,2573,89157,"0,0288592034",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"33,4","31,19"
many samples,UPN2_009,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),69709,1791,71716,"0,0249735066",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,144,Tolerated,"33,36","31,14"
"low freq, many samples",UPN2_010,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),53930,1485,55565,"0,0267254567",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"33,4","31,19"
"low freq, many samples",UPN2_011,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),67174,2388,69773,"0,0342252734",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"33,35","31,39"
"low freq, many artifacts, many samples",UPN2_055,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),61135,621,61927,"0,0100279361",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,144,Tolerated,"33,06","29,71"
"low freq, many samples",UPN2_057,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),55841,773,56777,"0,0136146679",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"33,18","30,11"
"low freq, many samples",UPN2_058,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),47202,901,48220,"0,0186851929",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"33,06","30,49"
"low freq, many samples",UPN2_059,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),58194,1898,60247,"0,0315036433",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"32,64","30,96"
"low freq, many samples",UPN2_012,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),33511,1037,34640,"0,0299364896",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"33,42","31,15"
"low freq, many samples",UPN2_060,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),42114,1947,44188,"0,0440617362",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"32,57","31,08"
"low freq, many samples",UPN2_040,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),63022,1619,64771,"0,0249957543",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"33,72","31,29"
"low freq, many samples",UPN2_013,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),18367,560,18977,"0,0295094061",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"33,3","31,17"
"low freq, many samples",UPN2_061,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),33754,1687,35531,"0,0474796656",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"32,68","31,13"
"low freq, many samples",UPN2_062,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),28592,1516,30178,"0,0502352707",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"32,63","31,19"
"low freq, many samples",UPN2_063,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),35529,1925,37551,"0,0512636148",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"32,55","31,03"
many samples,UPN2_064,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),40733,1948,42788,"0,0455267832",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,144,Tolerated,"32,72","31,08"
"low freq, many samples",UPN2_065,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),43055,1566,44734,"0,0350069299",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"32,63","30,86"
"low freq, many samples",UPN2_066,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),61401,2290,63855,"0,035862501",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"32,62","30,91"
"low freq, many samples",UPN2_067,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),63387,2257,65880,"0,0342592593",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"32,7","30,87"
"low freq, many samples",UPN2_068,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),41602,1628,43324,"0,0375773243",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"32,59","30,91"
"low freq, many samples",UPN2_069,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),47935,1964,50016,"0,0392674344",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"32,58","31,02"
"low freq, many samples",UPN2_070,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),29786,1365,31221,"0,0437205727",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"32,55","30,98"
many samples,UPN2_071,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),27448,1455,28978,"0,0502105045",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,144,Tolerated,"32,52","31,15"
many samples,UPN2_072,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),32833,1608,34533,"0,046564156",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,144,Tolerated,"32,58","30,98"
"low freq, many samples",UPN2_073,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),32260,1374,33720,"0,040747331",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"32,51","30,99"
"low freq, many samples",UPN2_074,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),29634,1203,30940,"0,0388817065",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"32,69","30,76"
"low freq, many samples",UPN2_075,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),43520,2046,45679,"0,0447908229",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"32,59","31,06"
"low freq, many samples",UPN2_076,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),39512,1850,41460,"0,0446213218",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"32,56","31,14"
"low freq, many samples",UPN2_077,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),41933,1815,43861,"0,0413807255",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"32,67","31,04"
"low freq, many samples",UPN2_078,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),36453,1799,38333,"0,0469308429",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"32,6","31,01"
"low freq, many samples",UPN2_079,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),23342,1130,24539,"0,0460491463",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"32,57","30,98"
"low freq, many samples",UPN2_080,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),37696,1948,39731,"0,0490297249",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"32,56",31
"low freq, many samples",UPN2_081,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),50247,2029,52397,"0,038723591",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"32,55","30,88"
"low freq, many samples",UPN2_082,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),59792,1942,61913,"0,0313665951",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"32,67","30,7"
"low freq, many samples",UPN2_083,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),49203,2374,51739,"0,0458841493",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"32,66","31,11"
"low freq, many samples",UPN2_084,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),51369,2125,53627,"0,0396255618",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"32,65","31,02"
"inspected, low freq, neutral effect",UPN2_085,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),46578,1672,48373,"0,0345647365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,144,Tolerated,"32,78","30,52"
"low freq, many samples",UPN2_086,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),36060,1257,37413,"0,0335979472",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"32,77","30,8"
"low freq, many samples",UPN2_087,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),57631,2357,60171,"0,039171694",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"32,63","30,84"
"low freq, many samples",UPN2_088,4,106157021,G,C,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly641Ala/c.1922G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),42407,1723,44252,"0,0389360933",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,144",Tolerated,"32,56","31,09"
"low bq, low freq, many artifacts",UPN2_049,4,106157056,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe653Ile/c.1957T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),48711,533,49477,"0,0107726823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,"0,01",Damaging,"31,16","18,74"
"low freq, many artifacts",UPN2_044,4,106157071,C,T,missense_variant(MODERATE|MISSENSE|Cac/Tac|p.His658Tyr/c.1972C>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),15144,154,15330,"0,0100456621",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,"1,65E-005",NO,NO,"-0,05",Neutral,1,Tolerated,"34,23","32,91"
"low bq, low freq, many artifacts, many samples",UPN2_041,4,106157078,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val660Glu/c.1979T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),24026,247,24484,"0,0100882209",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,714,Tolerated,"31,85","18,21"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106157078,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val660Glu/c.1979T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),76474,779,77696,"0,0100262562",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,714,Tolerated,"31,83",19
"low bq, low freq, many artifacts, many samples",UPN2_045,4,106157078,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val660Glu/c.1979T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),64760,660,65800,"0,0100303951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,714,Tolerated,"31,83","19,63"
"low bq, low freq, many artifacts, many samples",UPN2_046,4,106157078,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val660Glu/c.1979T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),60088,648,61102,"0,0106052175",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,714,Tolerated,"31,9","20,65"
"low bq, low freq, many artifacts, many samples",UPN2_050,4,106157078,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val660Glu/c.1979T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),58988,603,60011,"0,0100481578",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,714,Tolerated,"31,76","18,22"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106157078,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val660Glu/c.1979T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),42892,502,43667,"0,0114960954",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,714,Tolerated,"31,81","18,99"
"low bq, low freq, many artifacts, many samples",UPN2_053,4,106157078,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val660Glu/c.1979T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),61852,633,62824,"0,0100757672",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,714,Tolerated,"31,74","19,08"
"low bq, low freq, many artifacts, many samples",UPN2_054,4,106157078,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val660Glu/c.1979T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),46333,480,47088,"0,0101936799",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,714,Tolerated,"31,83","18,77"
"low bq, low freq, many artifacts, many samples",UPN2_055,4,106157078,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val660Glu/c.1979T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),66809,744,67958,"0,0109479384",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,714,Tolerated,"31,8","18,56"
"low bq, low freq, many artifacts, many samples",UPN2_056,4,106157078,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val660Glu/c.1979T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),25089,287,25531,"0,0112412361",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,714,Tolerated,"31,74","19,46"
"low bq, low freq, many artifacts",UPN2_057,4,106157078,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val660Glu/c.1979T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),65177,718,66219,"0,0108428095",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,714,Tolerated,"31,83","18,68"
"low bq, low freq, many artifacts",UPN2_041,4,106157084,T,A,missense_variant(MODERATE|MISSENSE|tTc/tAc|p.Phe662Tyr/c.1985T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),24072,252,24474,"0,0102966413",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,31",Neutral,"0,02",Damaging,"33,18","21,9"
"low freq, many artifacts",UPN2_044,4,106157087,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser663Tyr/c.1988C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),15109,159,15317,"0,0103806228",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,3,Damaging,"33,4","29,25"
"low bq, low freq, many artifacts, many samples",UPN2_059,4,106157096,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp666Ala/c.1997A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),46931,874,48015,"0,018202645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,4,Damaging,"29,41","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_060,4,106157096,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp666Ala/c.1997A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),31010,602,31716,"0,018980956",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,4,Damaging,"29,31","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_061,4,106157096,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp666Ala/c.1997A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),27518,580,28173,"0,0205870869",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,4,Damaging,"29,29","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_062,4,106157096,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp666Ala/c.1997A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),22728,472,23294,"0,0202627286",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,4,Damaging,"29,21","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_063,4,106157096,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp666Ala/c.1997A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),26818,494,27386,"0,0180384138",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,4,Damaging,"29,28","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_064,4,106157096,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp666Ala/c.1997A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),34695,666,35456,"0,0187838448",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,4,Damaging,"29,36","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_065,4,106157096,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp666Ala/c.1997A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),35576,666,36398,"0,0182977087",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,4,Damaging,"29,35","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_066,4,106157096,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp666Ala/c.1997A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),49907,925,51039,"0,0181233958",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,4,Damaging,"29,33","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_067,4,106157096,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp666Ala/c.1997A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),55310,1085,56599,"0,01916995",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,4,Damaging,"29,4","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_068,4,106157096,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp666Ala/c.1997A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),32396,709,33218,"0,0213438497",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,4,Damaging,"29,39","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_069,4,106157096,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp666Ala/c.1997A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),36708,769,37647,"0,0204265944",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,4,Damaging,"29,32","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_070,4,106157096,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp666Ala/c.1997A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),21721,424,22210,"0,0190904998",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,4,Damaging,"29,22","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_071,4,106157096,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp666Ala/c.1997A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),19646,337,20075,"0,0167870486",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,4,Damaging,"29,39","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106157096,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp666Ala/c.1997A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),25052,482,25633,"0,0188038856",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,4,Damaging,"29,45","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106157096,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp666Ala/c.1997A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),24562,483,25125,"0,0192238806",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,4,Damaging,"29,36","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_074,4,106157096,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp666Ala/c.1997A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),24686,477,25251,"0,018890341",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,4,Damaging,"29,31","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_075,4,106157096,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp666Ala/c.1997A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),32532,611,33271,"0,0183643413",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,4,Damaging,"29,37","14,2"
"low bq, low freq, many artifacts, many samples",UPN2_076,4,106157096,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp666Ala/c.1997A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),29391,599,30107,"0,0198957053",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,4,Damaging,"29,23","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_077,4,106157096,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp666Ala/c.1997A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),33815,693,34623,"0,0200155966",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,4,Damaging,"29,28","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_078,4,106157096,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp666Ala/c.1997A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),26401,545,27041,"0,0201545801",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,4,Damaging,"29,27","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_079,4,106157096,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp666Ala/c.1997A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),17433,313,17802,"0,0175822941",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,4,Damaging,"29,35","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_080,4,106157096,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp666Ala/c.1997A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),27152,480,27708,"0,0173235167",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,4,Damaging,"29,43","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106157096,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp666Ala/c.1997A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),37387,698,38221,"0,0182622119",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,4,Damaging,"29,43","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_082,4,106157096,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp666Ala/c.1997A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),50293,958,51428,"0,0186279848",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,4,Damaging,"29,32","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_083,4,106157096,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp666Ala/c.1997A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),39059,818,40012,"0,0204438668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,4,Damaging,"29,32","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_084,4,106157096,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp666Ala/c.1997A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),40658,768,41553,"0,01848242",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,4,Damaging,"29,34","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_085,4,106157096,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp666Ala/c.1997A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),42203,848,43212,"0,0196241785",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,4,Damaging,"29,36","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_086,4,106157096,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp666Ala/c.1997A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),31703,644,32465,"0,0198367473",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,4,Damaging,"29,33","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_087,4,106157096,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp666Ala/c.1997A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),46683,911,47782,"0,019065757",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,4,Damaging,"29,37","14,47"
"low bq, low freq, many artifacts",UPN2_088,4,106157096,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp666Ala/c.1997A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),32299,592,33010,"0,0179339594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,4,Damaging,"29,36","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_041,4,106157100,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His667Gln/c.2001T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),23850,285,24417,"0,0116721956",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,43",Neutral,77,Tolerated,"31,15","17,9"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106157100,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His667Gln/c.2001T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),75863,828,77518,"0,0106813901",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,43",Neutral,77,Tolerated,"31,29","17,79"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106157100,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His667Gln/c.2001T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),47381,525,48451,"0,0108356897",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,43",Neutral,77,Tolerated,"31,33","16,73"
"low bq, low freq, many artifacts, many samples",UPN2_045,4,106157100,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His667Gln/c.2001T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),64266,659,65676,"0,0100341068",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,43",Neutral,77,Tolerated,"31,28","16,37"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106157100,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His667Gln/c.2001T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),48273,550,49375,"0,0111392405",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,43",Neutral,77,Tolerated,"31,22","17,64"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106157100,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His667Gln/c.2001T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),42657,489,43559,"0,011226153",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,43",Neutral,77,Tolerated,"31,23","17,13"
"low bq, low freq, many artifacts, many samples",UPN2_052,4,106157100,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His667Gln/c.2001T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),48440,533,49507,"0,0107661543",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,43",Neutral,77,Tolerated,"31,21","16,85"
"low bq, low freq, many artifacts, many samples",UPN2_053,4,106157100,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His667Gln/c.2001T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),61411,654,62701,"0,0104304557",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,43",Neutral,77,Tolerated,"31,16","16,83"
"low bq, low freq, many artifacts, many samples",UPN2_054,4,106157100,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His667Gln/c.2001T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),45972,474,46988,"0,010087682",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,43",Neutral,77,Tolerated,"31,02","16,29"
"low bq, low freq, many artifacts, many samples",UPN2_055,4,106157100,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His667Gln/c.2001T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),66461,687,67820,"0,0101297552",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,43",Neutral,77,Tolerated,"31,17","17,29"
"low bq, low freq, many artifacts, many samples",UPN2_056,4,106157100,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His667Gln/c.2001T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),24924,276,25478,"0,0108328754",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,43",Neutral,77,Tolerated,"31,22","16,9"
"low bq, low freq, many artifacts, many samples",UPN2_057,4,106157100,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His667Gln/c.2001T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),64758,667,66061,"0,0100967288",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,43",Neutral,77,Tolerated,"31,27","17,16"
"low bq, low freq, many artifacts",UPN2_058,4,106157100,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His667Gln/c.2001T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),51781,628,52893,"0,0118730267",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,43",Neutral,77,Tolerated,"31,24","16,97"
"low bq, low freq, many artifacts, many samples",UPN2_041,4,106157101,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu668Ile/c.2002T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),24041,296,24408,"0,0121271714",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,53",Neutral,307,Tolerated,"31,63","17,91"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106157101,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu668Ile/c.2002T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),76185,937,77502,"0,0120900106",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,53",Neutral,307,Tolerated,"31,67","18,83"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106157101,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu668Ile/c.2002T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),47563,648,48449,"0,0133748891",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,53",Neutral,307,Tolerated,"31,66","18,68"
"low bq, low freq, many artifacts, many samples",UPN2_044,4,106157101,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu668Ile/c.2002T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),15053,169,15288,"0,0110544218",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,53",Neutral,307,Tolerated,"31,73","16,78"
"low bq, low freq, many artifacts, many samples",UPN2_045,4,106157101,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu668Ile/c.2002T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),64526,774,65658,"0,0117883579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,53",Neutral,307,Tolerated,"31,65","18,53"
"low bq, low freq, many artifacts, many samples",UPN2_046,4,106157101,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu668Ile/c.2002T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),60088,654,60976,"0,0107255314",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,53",Neutral,307,Tolerated,"31,69","18,63"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106157101,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu668Ile/c.2002T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),91310,1182,92903,"0,0127229476",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,53",Neutral,307,Tolerated,"31,71","20,54"
"low bq, low freq, many artifacts, many samples",UPN2_048,4,106157101,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu668Ile/c.2002T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),55622,641,56468,"0,0113515619",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,53",Neutral,307,Tolerated,"31,71","17,75"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106157101,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu668Ile/c.2002T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),48459,657,49362,"0,0133098335",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,53",Neutral,307,Tolerated,"31,58","18,54"
"low bq, low freq, many artifacts, many samples",UPN2_050,4,106157101,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu668Ile/c.2002T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),58895,709,59896,"0,0118371845",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,53",Neutral,307,Tolerated,"31,56","18,13"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106157101,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu668Ile/c.2002T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),42774,596,43548,"0,0136860476",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,53",Neutral,307,Tolerated,"31,58","19,38"
"low bq, low freq, many artifacts, many samples",UPN2_052,4,106157101,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu668Ile/c.2002T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),48702,546,49493,"0,0110318631",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,53",Neutral,307,Tolerated,"31,65","18,34"
"low bq, low freq, many artifacts, many samples",UPN2_053,4,106157101,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu668Ile/c.2002T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),61717,713,62682,"0,0113748764",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,53",Neutral,307,Tolerated,"31,54","18,66"
"low bq, low freq, many artifacts, many samples",UPN2_054,4,106157101,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu668Ile/c.2002T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),46200,556,46978,"0,0118353272",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,53",Neutral,307,Tolerated,"31,58","18,1"
"low bq, low freq, many artifacts, many samples",UPN2_055,4,106157101,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu668Ile/c.2002T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),66630,897,67804,"0,013229308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,53",Neutral,307,Tolerated,"31,6","18,77"
"low bq, low freq, many artifacts, many samples",UPN2_056,4,106157101,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu668Ile/c.2002T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),24968,367,25469,"0,0144096745",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,53",Neutral,307,Tolerated,"31,54","20,47"
"low bq, low freq, many artifacts, many samples",UPN2_057,4,106157101,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu668Ile/c.2002T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),64917,878,66045,"0,0132939662",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,53",Neutral,307,Tolerated,"31,6","18,77"
"low bq, low freq, many artifacts, many samples",UPN2_058,4,106157101,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu668Ile/c.2002T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),52011,687,52880,"0,0129916793",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,53",Neutral,307,Tolerated,"31,65","18,27"
"low bq, low freq, many artifacts, many samples",UPN2_061,4,106157101,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu668Ile/c.2002T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),27721,287,28133,"0,0102015427",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,53",Neutral,307,Tolerated,"30,78","16,35"
"low bq, low freq, many artifacts, many samples",UPN2_065,4,106157101,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu668Ile/c.2002T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),35841,379,36352,"0,0104258363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,53",Neutral,307,Tolerated,"30,82","17,46"
"low bq, low freq, many artifacts, many samples",UPN2_066,4,106157101,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu668Ile/c.2002T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),50279,529,50981,"0,0103764147",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,53",Neutral,307,Tolerated,"30,75","16,66"
"low bq, low freq, many artifacts, many samples",UPN2_067,4,106157101,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu668Ile/c.2002T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),55699,589,56520,"0,0104210899",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,53",Neutral,307,Tolerated,"30,8","18,33"
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106157101,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu668Ile/c.2002T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),25230,271,25598,"0,0105867646",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,53",Neutral,307,Tolerated,"30,82","18,41"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106157101,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu668Ile/c.2002T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),24691,294,25080,"0,011722488",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,53",Neutral,307,Tolerated,"30,71","17,68"
"low bq, low freq, many artifacts, many samples",UPN2_074,4,106157101,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu668Ile/c.2002T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),24867,270,25228,"0,0107023942",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,53",Neutral,307,Tolerated,"30,71","18,03"
"low bq, low freq, many artifacts, many samples",UPN2_076,4,106157101,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu668Ile/c.2002T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),29618,335,30072,"0,0111399308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,53",Neutral,307,Tolerated,"30,82","18,56"
"low bq, low freq, many artifacts, many samples",UPN2_077,4,106157101,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu668Ile/c.2002T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),34059,348,34582,"0,0100630386",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,53",Neutral,307,Tolerated,"30,74",19
"low bq, low freq, many artifacts, many samples",UPN2_080,4,106157101,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu668Ile/c.2002T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),27276,287,27673,"0,0103711199",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,53",Neutral,307,Tolerated,"30,8","17,73"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106157101,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu668Ile/c.2002T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),37639,394,38171,"0,0103219722",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,53",Neutral,307,Tolerated,"30,85","17,91"
"low bq, low freq, many artifacts, many samples",UPN2_082,4,106157101,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu668Ile/c.2002T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),50609,514,51377,"0,0100044767",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,53",Neutral,307,Tolerated,"30,73","17,76"
"low bq, low freq, many artifacts, many samples",UPN2_085,4,106157101,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu668Ile/c.2002T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),42510,472,43153,"0,0109378259",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,53",Neutral,307,Tolerated,"30,79","18,09"
"low bq, low freq, many artifacts, many samples",UPN2_087,4,106157101,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu668Ile/c.2002T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),47023,506,47730,"0,010601299",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,53",Neutral,307,Tolerated,"30,83","17,94"
"low bq, low freq, many artifacts",UPN2_088,4,106157101,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu668Ile/c.2002T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),32474,338,32954,"0,0102567215",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,53",Neutral,307,Tolerated,"30,82","18,56"
"low bq, low freq, many artifacts, many samples",UPN2_054,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),13315,137,13625,"0,0100550459",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,85","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_056,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),3807,48,3901,"0,0123045373",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,97",14
"low bq, low freq, many artifacts, many samples",UPN2_090,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),8285,100,8520,"0,0117370892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,19","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_059,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),22490,318,23226,"0,0136915526",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,61","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_060,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),34874,527,36038,"0,014623453",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,52","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_091,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),8459,107,8705,"0,0122917863",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,41",14
"low bq, low freq, many artifacts, many samples",UPN2_092,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),5749,62,5895,"0,0105173876",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,18",14
"low bq, low freq, many artifacts, many samples",UPN2_061,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),25507,330,26327,"0,0125346602",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,56","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_062,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),22455,345,23162,"0,0148950868",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,52","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_063,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),27505,372,28418,"0,0130902949",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,67","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_064,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),19838,255,20429,"0,0124822556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,64","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_065,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),20115,268,20788,"0,0128920531",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,72","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_066,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),27636,351,28586,"0,0122787378",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,54","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_067,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),27771,354,28652,"0,0123551585",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,72","14,13"
"low bq, low freq, many artifacts, many samples",UPN2_068,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),20625,270,21286,"0,0126843935",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,58","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_069,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),33955,502,35161,"0,0142771821",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,63","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_070,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),23905,335,24751,"0,0135348067",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,52","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_071,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),21653,273,22310,"0,0122366652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,67","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),24427,303,25226,"0,0120114168",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,7","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),20276,245,20913,"0,0117152011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,5","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_074,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),15310,196,15799,"0,0124058485",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,59","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_075,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),36674,443,37807,"0,0117174068",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,63","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_076,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),33904,452,34962,"0,0129283222",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,58","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_077,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),29681,437,30686,"0,014241022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,49","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_078,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),31336,451,32367,"0,0139339451",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,52","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_079,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),19698,250,20313,"0,0123073894",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,63","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_080,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),31753,441,32791,"0,0134488122",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,63","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),35880,495,37106,"0,0133401606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,69","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_082,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),29301,370,30262,"0,0122265548",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,63","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_083,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),37275,546,38493,"0,0141843972",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,55","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_084,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),40056,511,41359,"0,012355231",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,65","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_085,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),27224,362,28105,"0,0128802704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,69","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_086,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),17514,243,18097,"0,0134276399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,58","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_087,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),35591,409,36689,"0,0111477555",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,71","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_088,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),29688,377,30584,"0,0123267068",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,62","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_094,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),11444,127,11713,"0,0108426535",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,27","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_095,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),12278,157,12614,"0,012446488",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,3","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_096,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),10051,129,10295,"0,0125303545",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,19","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_098,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),11803,137,12123,"0,0113008331",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,18","14,18"
"low bq, low freq, many artifacts, many samples",UPN2_099,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),6436,87,6618,"0,0131459655",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,2","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_101,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),11709,174,12024,"0,0144710579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,21","14,2"
"low bq, low freq, many artifacts, many samples",UPN2_102,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),12678,203,13055,"0,0155495979",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,22","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_103,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),14017,193,14419,"0,0133851169",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,14","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_104,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),13992,166,14367,"0,0115542563",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,17","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_105,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),12933,169,13270,"0,0127354936",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,29","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_106,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),15322,158,15698,"0,0100649764",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,39","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_107,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),19453,253,19992,"0,012655062",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,2","14,19"
"low bq, low freq, many artifacts, many samples",UPN2_108,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),21880,251,22411,"0,0111998572",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,29","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_109,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),20591,251,21149,"0,0118681734",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,35","14,05"
"low bq, low freq, many artifacts, many samples",UPN2_110,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),15673,204,16096,"0,0126739563",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,21","14,45"
"low bq, low freq, many artifacts",UPN2_111,4,106157202,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln701His/c.2103G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),16826,220,17243,"0,0127588007",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,27","14,2"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),20803,261,21302,"0,0122523707",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,01","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),13728,171,14037,"0,0121820902",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,09","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_045,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),12533,137,12831,"0,010677266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,1","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_046,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),15747,193,16128,"0,0119667659",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,09","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),16725,202,17126,"0,0117949317",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,16","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_048,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),3266,46,3353,"0,0137190576",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,09",14
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),9608,118,9862,"0,0119651186",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,93","15,17"
"low bq, low freq, many artifacts, many samples",UPN2_050,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),11369,120,11622,"0,0103252452",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,83","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),19589,215,20019,"0,0107397972",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,97","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_052,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),10622,124,10870,"0,0114075437",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,94","14,2"
"low bq, low freq, many artifacts, many samples",UPN2_053,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),22206,257,22732,"0,0113056484",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,88","15,34"
"low bq, low freq, many artifacts, many samples",UPN2_054,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),13315,140,13625,"0,0102752294",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,85","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_055,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),20086,216,20529,"0,010521701",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,98","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_056,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),3807,42,3901,"0,0107664701",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,97","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_090,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),8285,127,8520,"0,0149061033",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,19","16,82"
"low bq, low freq, many artifacts, many samples",UPN2_057,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),15235,167,15557,"0,0107347175",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,08","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_058,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),20383,216,20784,"0,0103926097",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,23","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_059,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),22490,398,23226,"0,0171359683",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,61","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_060,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),34874,600,36038,"0,0166490926",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,52","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_091,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),8459,122,8705,"0,0140149339",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,41","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_092,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),5749,76,5895,"0,0128922816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,18","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_093,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),7363,81,7523,"0,0107669813",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,35",14
"low bq, low freq, many artifacts, many samples",UPN2_061,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),25507,458,26327,"0,0173965891",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,56","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_062,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),22455,340,23162,"0,014679216",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,52","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_063,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),27505,505,28418,"0,0177704272",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,67","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_064,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),19838,323,20429,"0,0158108571",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,64","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_065,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),20115,391,20788,"0,0188089282",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,72","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_066,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),27636,542,28586,"0,0189603302",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,54","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_067,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),27771,506,28652,"0,0176601982",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,72","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_068,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),20625,364,21286,"0,0171004416",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,58","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_069,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),33955,669,35161,"0,0190267626",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,63","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_070,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),23905,482,24751,"0,0194739606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,52","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_071,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),21653,371,22310,"0,0166293142",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,67","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),24427,468,25226,"0,0185522873",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,7","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),20276,356,20913,"0,0170229044",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,5","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_074,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),15310,278,15799,"0,0175960504",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,59","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_075,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),36674,650,37807,"0,0171925834",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,63","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_076,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),33904,564,34962,"0,0161318002",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,58","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_077,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),29681,530,30686,"0,01727172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,49","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_078,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),31336,522,32367,"0,0161275373",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,52","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_079,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),19698,349,20313,"0,0171811155",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,63","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_080,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),31753,564,32791,"0,0171998414",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,63","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),35880,685,37106,"0,0184606263",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,69","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_082,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),29301,560,30262,"0,0185050558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,63","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_083,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),37275,630,38493,"0,0163666121",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,55","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_084,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),40056,743,41359,"0,017964651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,65","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_085,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),27224,490,28105,"0,0174346202",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,69","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_086,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),17514,313,18097,"0,0172956844",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,58","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_087,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),35591,644,36689,"0,017552945",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,71","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_088,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),29688,487,30584,"0,0159233586",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"28,62","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_094,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),11444,127,11713,"0,0108426535",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,27","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_095,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),12278,162,12614,"0,012842873",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,3","15,69"
"low bq, low freq, many artifacts, many samples",UPN2_096,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),10051,105,10295,"0,0101991258",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,19","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_097,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),11343,152,11621,"0,0130797694",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,43","15,71"
"low bq, low freq, many artifacts, many samples",UPN2_098,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),11803,169,12123,"0,0139404438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,18","15,91"
"low bq, low freq, many artifacts, many samples",UPN2_099,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),6436,89,6618,"0,0134481717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,2","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_100,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),15048,208,15426,"0,0134837288",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,36","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_101,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),11709,136,12024,"0,0113107119",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,21","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_102,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),12678,155,13055,"0,0118728457",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,22","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_103,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),14017,191,14419,"0,013246411",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,14","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_104,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),13992,182,14367,"0,0126679195",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,17","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_105,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),12933,163,13270,"0,0122833459",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,29","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_106,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),15322,192,15698,"0,0122308574",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,39","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_107,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),19453,272,19992,"0,0136054422",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,2","15,85"
"low bq, low freq, many artifacts, many samples",UPN2_108,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),21880,262,22411,"0,0116906876",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,29","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_109,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),20591,274,21149,"0,0129556953",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,35","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_110,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),15673,184,16096,"0,0114314115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,21","14,62"
"low bq, low freq, many artifacts",UPN2_111,4,106157202,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln701His/c.2103G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),16826,182,17243,"0,0105550078",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,0,Damaging,"27,27","14,47"
inspected,UPN2_044,4,106157203,C,T,missense_variant(MODERATE|MISSENSE|Cac/Tac|p.His702Tyr/c.2104C>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),3072,87,3169,"0,0274534553",0,0,0,0,1,1,0,1,3,NO,NO,"COSM4584703, COSM4584704",bone,2,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,"0,001",Damaging,"32,61","35,01"
"low freq, many artifacts",UPN2_048,4,106157237,T,C,missense_variant(MODERATE|MISSENSE|tTt/tCt|p.Phe713Ser/c.2138T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),3298,58,3366,"0,0172311349",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,0,Damaging,"33,4","33,62"
"low freq, many artifacts",UPN2_044,4,106157252,T,C,missense_variant(MODERATE|MISSENSE|cTt/cCt|p.Leu718Pro/c.2153T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),3134,34,3183,"0,0106817468",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,01",Neutral,"0,11",Tolerated,"33,41","32,59"
"low freq, many artifacts",UPN2_056,4,106157258,A,T,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln720Leu/c.2159A>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),3834,58,3922,"0,0147883733",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,"0,074",Tolerated,"34,35","32,52"
"low freq, many artifacts",UPN2_044,4,106157261,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His721Arg/c.2162A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),3129,44,3183,"0,013823437",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,61",Neutral,"0,036",Damaging,"34,49","32,27"
"low freq, many artifacts",UPN2_056,4,106157263,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys722Glu/c.2164A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),3840,69,3923,"0,0175885802",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,18",Neutral,"0,214",Tolerated,"34,64","33,59"
"low freq, many artifacts",UPN2_004,4,106157272,A,T,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys725*/c.2173A>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),1821,21,1852,"0,0113390929",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,79","28,71"
many samples,UPN2_001,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),12612,605,13248,"0,0456672705",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,29,Damaging,"32,94","31,43"
many samples,UPN2_014,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),20466,689,21197,"0,0325045997",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,29,Damaging,"32,98","31,53"
"low freq, many artifacts, many samples",UPN2_015,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),30404,668,31144,"0,0214487542",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,29,Damaging,"33,13","31,5"
"inspected, strandbias, many samples",UPN2_016,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),14854,381,15280,"0,024934555",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"33,24","31,65"
many samples,UPN2_017,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),9511,337,9885,"0,0340920587",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,29,Damaging,"32,94","31,57"
"strandbias, many samples",UPN2_018,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),16064,416,16522,"0,0251785498",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"33,25","31,65"
many samples,UPN2_019,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),17843,532,18410,"0,0288973384",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,29,Damaging,"33,23","31,66"
many samples,UPN2_020,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),12100,439,12559,"0,0349550123",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,29,Damaging,"32,84","31,66"
many samples,UPN2_021,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),15432,475,15956,"0,0297693658",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,29,Damaging,"33,09","31,65"
"strandbias, many samples",UPN2_002,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),15429,845,16309,"0,051811883",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"32,75","31,5"
many samples,UPN2_003,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),3032,131,3173,"0,0412858494",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,29,Damaging,"32,66","31,66"
many samples,UPN2_022,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),22351,633,23038,"0,0274763434",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,29,Damaging,"32,98","31,51"
"strandbias, many samples",UPN2_023,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),23107,626,23793,"0,0263102593",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"32,94","31,68"
"low freq, many artifacts, many samples",UPN2_041,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),9933,162,10134,"0,0159857904",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,29,Damaging,"31,65","31,3"
many samples,UPN2_024,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),11580,292,11900,"0,0245378151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,29,Damaging,"32,88","31,44"
many samples,UPN2_025,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),27753,676,28513,"0,0237084838",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,29,Damaging,"33,3","31,6"
"strandbias, many samples",UPN2_026,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),27146,774,27988,"0,0276547092",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"33,1","31,48"
"strandbias, many samples",UPN2_004,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),2759,130,2891,"0,0449671394",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"32,82","31,45"
"strandbias, many samples",UPN2_027,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),27760,992,28838,"0,0343990568",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"33,05","31,58"
"low freq, many artifacts, many samples",UPN2_042,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),39527,590,40238,"0,0146627566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,29,Damaging,"32,45","31,17"
many samples,UPN2_028,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),19542,574,20167,"0,0284623395",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,29,Damaging,"33,02","31,55"
"strandbias, many samples",UPN2_043,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),24394,421,24919,"0,016894739",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"32,52","31,14"
"strandbias, many samples",UPN2_044,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),7123,132,7258,"0,0181868283",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"32,33","31,37"
"strandbias, many samples",UPN2_029,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),21335,777,22172,"0,0350441999",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"32,71","31,55"
"strandbias, many samples",UPN2_030,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),23439,693,24188,"0,0286505705",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"33,14","31,59"
"low freq, many artifacts, many samples",UPN2_031,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),16076,360,16475,"0,0218512898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,29,Damaging,"33,22","31,45"
many samples,UPN2_005,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),4685,256,4947,"0,0517485345",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,29,Damaging,"32,9","31,64"
"low freq, many artifacts, many samples",UPN2_045,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),29852,316,30255,"0,0104445546",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,29,Damaging,"32,29","31,3"
many samples,UPN2_032,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),7882,250,8150,"0,0306748466",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,29,Damaging,"32,8","31,86"
"strandbias, many samples",UPN2_046,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),28819,624,29496,"0,0211554109",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"32,56","30,73"
"strandbias, many samples",UPN2_033,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),18412,506,18986,"0,0266512167",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"33,02","31,63"
"strandbias, many samples",UPN2_034,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),6549,187,6751,"0,0276996001",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"32,88","31,56"
"strandbias, many samples",UPN2_047,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),43127,819,44097,"0,018572692",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"32,26","31,15"
many samples,UPN2_048,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),23159,567,23766,"0,0238576117",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,29,Damaging,"31,89","31,53"
"strandbias, many samples",UPN2_035,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),36466,1055,37600,"0,0280585106",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"32,83","31,45"
"strandbias, many samples",UPN2_036,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),30235,1008,31335,"0,0321685017",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"32,69","31,5"
"strandbias, many samples",UPN2_006,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),21208,1126,22375,"0,0503240223",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"32,83","31,63"
"strandbias, many samples",UPN2_049,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),21769,437,22281,"0,0196131233",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"32,36","31,48"
many samples,UPN2_037,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),28097,685,28858,"0,0237369187",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,29,Damaging,"32,96","31,58"
many samples,UPN2_038,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),40226,979,41337,"0,0236833829",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,29,Damaging,"33,13","31,49"
many samples,UPN2_039,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),31695,856,32635,"0,0262295082",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,29,Damaging,"33,02","31,6"
"strandbias, many samples",UPN2_053,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),34540,579,35213,"0,016442791",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"32,68","31,38"
"low freq, many artifacts, many samples",UPN2_054,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),23324,256,23646,"0,0108263554",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,29,Damaging,"32,55","30,94"
"strandbias, many samples",UPN2_007,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),38746,1361,40251,"0,0338128245",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"32,87","31,34"
"strandbias, many samples",UPN2_008,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),46896,1663,48690,"0,0341548573",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"32,75","31,52"
"strandbias, many samples",UPN2_009,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),38217,1110,39425,"0,0281547242",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"32,8","31,47"
"strandbias, many samples",UPN2_010,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),30972,1036,32067,"0,0323073565",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"32,95","31,57"
"strandbias, many samples",UPN2_011,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),38198,1327,39623,"0,0334906494",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"32,75","31,57"
"low freq, many artifacts, many samples",UPN2_055,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),36465,483,37046,"0,0130378448",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,29,Damaging,"32,55","31,3"
"low freq, many artifacts, many samples",UPN2_056,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),11356,173,11557,"0,0149692827",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,29,Damaging,"32,22","31,15"
"strandbias, many samples",UPN2_057,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),29550,469,30090,"0,0155865736",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"32,41","31,35"
"low freq, many artifacts, many samples",UPN2_058,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),29866,613,30553,"0,0200634962",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,29,Damaging,"32,73","31,1"
"strandbias, many samples",UPN2_059,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),47869,1605,49624,"0,032343221",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"32,44","31,34"
"strandbias, many samples",UPN2_012,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),17426,617,18074,"0,034137435",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"32,81","31,62"
many samples,UPN2_060,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),37208,1212,38513,"0,0314698933",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,29,Damaging,"33,18","31,18"
"strandbias, many samples",UPN2_040,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),37962,1164,39213,"0,0296840334",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"32,75","31,67"
"strandbias, many samples",UPN2_013,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),10086,375,10481,"0,0357790287",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"32,92","31,7"
"strandbias, many samples",UPN2_061,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),28610,949,29621,"0,0320380811",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"33,09","31,26"
"strandbias, many samples",UPN2_062,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),25243,1023,26318,"0,0388707349",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"33,15","31,49"
many samples,UPN2_063,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),30551,1138,31776,"0,0358131923",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,29,Damaging,"33,12","31,18"
"strandbias, many samples",UPN2_064,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),30782,1437,32298,"0,044491919",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"32,72","31,39"
"strandbias, many samples",UPN2_065,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),33064,1120,34263,"0,0326883227",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"32,66","31,22"
"strandbias, many samples",UPN2_066,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),51429,1968,53551,"0,036750014",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"32,53","31,39"
many samples,UPN2_067,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),55334,2307,57780,"0,0399273105",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,29,Damaging,"32,48","31,28"
"strandbias, many samples",UPN2_068,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),34660,1362,36127,"0,0377003349",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"32,61","31,37"
"strandbias, many samples",UPN2_069,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),41231,1381,42723,"0,032324509",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,33,"31,19"
"strandbias, many samples",UPN2_070,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),28147,960,29170,"0,0329105245",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"33,03","31,19"
"strandbias, many samples",UPN2_071,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),22199,792,23089,"0,0343020486",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"33,25","31,16"
"strandbias, many samples",UPN2_072,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),25281,770,26123,"0,0294759407",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"33,22","31,23"
"strandbias, many samples",UPN2_073,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),25993,690,26746,"0,0257982502",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"32,95","31,4"
"strandbias, many samples",UPN2_074,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),25069,895,26034,"0,0343781209",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"32,65","31,38"
"strandbias, many samples",UPN2_075,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),39557,1139,40806,"0,0279125619",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"33,16","31,01"
"strandbias, many samples",UPN2_076,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),38071,1093,39281,"0,0278251572",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"33,13","31,48"
many samples,UPN2_077,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),38269,1127,39495,"0,0285352576",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,29,Damaging,"32,95",31
"inspected, strandbias",UPN2_078,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),34002,946,35032,"0,0270038822",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,29,Damaging,"33,18","31,26"
"strandbias, many samples",UPN2_079,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),22212,622,22878,"0,0271876912",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"33,09","31,2"
"strandbias, many samples",UPN2_080,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),33890,998,34973,"0,0285362994",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"33,16","31,17"
"strandbias, many samples",UPN2_081,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),42827,1044,43946,"0,0237564283",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,33,"31,08"
"strandbias, many samples",UPN2_082,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),50458,1400,52029,"0,0269080705",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"32,59","31,08"
"strandbias, many samples",UPN2_083,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),42324,1538,43966,"0,0349815767",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"33,11","31,34"
"strandbias, many samples",UPN2_084,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),50268,1302,51690,"0,0251886245",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"32,95","31,17"
"strandbias, many samples",UPN2_085,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),49272,1471,50873,"0,0289151416",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"32,56","31,29"
"strandbias, many samples",UPN2_086,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),42361,1354,43848,"0,0308794016",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"32,34","31,28"
"strandbias, many samples",UPN2_087,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),50874,1460,52502,"0,0278084644",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"32,8","31,19"
"strandbias, many samples",UPN2_088,4,106157294,C,G,missense_variant(MODERATE|MISSENSE|cCa/cGa|p.Pro732Arg/c.2195C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),37954,1369,39405,"0,034741784",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,029",Damaging,"32,97","31,17"
"low freq, many artifacts",UPN2_044,4,106157312,TC,T,frameshift_variant(HIGH||cct/|p.Pro739fs/c.2216delC|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),7262,121,7411,"0,0163270814",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,NA,NA,NA,NA,"35,01",NA
"low freq, many artifacts, many samples",UPN2_047,4,106157317,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln740Lys/c.2218C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),43924,460,44449,"0,0103489392",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,79",Neutral,56,Tolerated,"35,37","33,93"
"low freq, many artifacts, many samples",UPN2_052,4,106157317,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln740Lys/c.2218C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),23784,251,24079,"0,0104240209",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,79",Neutral,56,Tolerated,"35,36","34,21"
"low freq, many artifacts, many samples",UPN2_004,4,106157352,G,C,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys751Asn/c.2253G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),2858,31,2895,"0,0107081174",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,2,Damaging,"33,62","30,84"
"low freq, many artifacts, many samples",UPN2_005,4,106157352,G,C,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys751Asn/c.2253G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),4902,58,4966,"0,0116794201",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,2,Damaging,"33,67","30,53"
"many samples, low freq, many artifacts",UPN2_006,4,106157352,G,C,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys751Asn/c.2253G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),22120,250,22408,"0,0111567297",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,"0,002",Damaging,"33,66","30,76"
"many samples, low freq, many artifacts",UPN2_060,4,106157352,G,C,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys751Asn/c.2253G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),37994,483,38586,"0,0125174934",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,"0,002",Damaging,"33,28","30,65"
"many samples, low freq, many artifacts",UPN2_061,4,106157352,G,C,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys751Asn/c.2253G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),29272,370,29702,"0,0124570736",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,"0,002",Damaging,"33,37","30,63"
"many samples, low freq, many artifacts",UPN2_062,4,106157352,G,C,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys751Asn/c.2253G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),26001,384,26446,"0,0145201543",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,"0,002",Damaging,"33,41","30,75"
"many samples, low freq, many artifacts",UPN2_063,4,106157352,G,C,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys751Asn/c.2253G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),31400,445,31898,"0,0139507179",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,"0,002",Damaging,"33,39","30,5"
"low freq, many artifacts, many samples",UPN2_064,4,106157352,G,C,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys751Asn/c.2253G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),32111,331,32505,"0,0101830488",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,2,Damaging,"33,84","29,71"
"many samples, low freq, many artifacts",UPN2_069,4,106157352,G,C,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys751Asn/c.2253G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),42312,482,42875,"0,0112419825",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,"0,002",Damaging,"33,48","30,4"
"many samples, low freq, many artifacts",UPN2_071,4,106157352,G,C,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys751Asn/c.2253G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),22714,336,23096,"0,0145479737",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,"0,002",Damaging,"33,25","30,51"
"many samples, low freq, many artifacts",UPN2_072,4,106157352,G,C,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys751Asn/c.2253G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),25791,403,26237,"0,0153599878",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,"0,002",Damaging,"33,25","30,53"
"many samples, low freq, many artifacts",UPN2_075,4,106157352,G,C,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys751Asn/c.2253G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),40252,557,40889,"0,0136222456",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,"0,002",Damaging,"33,31","30,35"
"many samples, low freq, many artifacts",UPN2_076,4,106157352,G,C,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys751Asn/c.2253G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),38803,519,39412,"0,0131685781",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,"0,002",Damaging,"33,4","30,73"
"low freq, many artifacts",UPN2_078,4,106157352,G,C,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys751Asn/c.2253G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),34545,481,35101,"0,0137033133",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,2,Damaging,"33,33","31,05"
"many samples, low freq, many artifacts",UPN2_079,4,106157352,G,C,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys751Asn/c.2253G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),22561,283,22895,"0,0123607775",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,"0,002",Damaging,"33,36","30,92"
"many samples, low freq, many artifacts",UPN2_080,4,106157352,G,C,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys751Asn/c.2253G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),34502,476,35047,"0,0135817616",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,"0,002",Damaging,"33,35","30,56"
"many samples, low freq, many artifacts",UPN2_083,4,106157352,G,C,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys751Asn/c.2253G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),43598,568,44271,"0,0128300693",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,"0,002",Damaging,"33,46","30,66"
"many samples, low freq, many artifacts",UPN2_084,4,106157352,G,C,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys751Asn/c.2253G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),51195,539,51846,"0,0103961733",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,"0,002",Damaging,"33,53","30,57"
"low freq, many artifacts",UPN2_044,4,106157366,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile756Lys/c.2267T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),5702,112,5823,"0,0192340718",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,"0,009",Damaging,"34,14","27,3"
"low bq, low freq, many artifacts",UPN2_047,4,106157368,C,A,missense_variant(MODERATE|MISSENSE|Ctc/Atc|p.Leu757Ile/c.2269C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),70523,729,71404,"0,0102095121",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,55,Tolerated,"32,12","17,23"
"low freq, many artifacts",UPN2_041,4,106157384,AC,A,frameshift_variant(HIGH||caa/|p.Gln764fs/c.2290delC|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),20230,222,20512,"0,0108229329",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,37",NA
"low freq, many artifacts",UPN2_053,4,106157404,C,T,stop_gained(HIGH|NONSENSE|Cag/Tag|p.Gln769*/c.2305C>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),47347,750,48250,"0,0155440415",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,NA,NA,NA,NA,"34,08","33,19"
"low freq, many artifacts",UPN2_044,4,106157423,T,C,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe775Ser/c.2324T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),11447,117,11634,"0,0100567303",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,34",Neutral,632,Tolerated,"33,22","32,77"
"low freq, many artifacts",UPN2_044,4,106157426,T,A,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe776Tyr/c.2327T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),11320,206,11630,"0,0177128117",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,"0,007",Damaging,"32,69","28,97"
"low bq, low freq, many artifacts, many samples",UPN2_063,4,106157506,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln803Lys/c.2407C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),63324,648,64082,"0,0101120439",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,3,Damaging,"31,41","16,67"
"low bq, low freq, many artifacts, many samples",UPN2_066,4,106157506,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln803Lys/c.2407C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),130820,1343,132414,"0,0101424321",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,3,Damaging,"31,47","16,61"
"low bq, low freq, many artifacts, many samples",UPN2_069,4,106157506,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln803Lys/c.2407C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),89735,912,90824,"0,0100413987",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,3,Damaging,"31,37","16,61"
"low bq, low freq, many artifacts, many samples",UPN2_071,4,106157506,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln803Lys/c.2407C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),49200,516,49822,"0,0103568705",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,3,Damaging,"31,13","16,62"
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106157506,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln803Lys/c.2407C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),46522,488,47102,"0,0103604942",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,3,Damaging,"31,4","16,63"
"low bq, low freq, many artifacts, many samples",UPN2_078,4,106157506,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln803Lys/c.2407C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),71038,763,72010,"0,0105957506",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,3,Damaging,"31,3","17,43"
"low bq, low freq, many artifacts, many samples",UPN2_082,4,106157506,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln803Lys/c.2407C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),111935,1138,113320,"0,0100423579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,3,Damaging,"31,65","17,03"
"low bq, low freq, many artifacts",UPN2_086,4,106157506,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln803Lys/c.2407C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),108443,1104,109769,"0,0100574844",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,3,Damaging,"31,66","16,66"
"inspected, many artifacts",UPN2_048,4,106157519,A,G,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu807Gly/c.2420A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),1011,63,1077,"0,0584958217",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,13",Neutral,1,Damaging,"33,67","31,83"
"low freq, many artifacts",UPN2_056,4,106157519,A,G,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu807Gly/c.2420A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),2632,32,2670,"0,0119850187",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,13",Neutral,"0,001",Damaging,"33,93","32,88"
"low freq, many artifacts",UPN2_044,4,106157569,A,G,missense_variant(MODERATE|MISSENSE|Aaa/Gaa|p.Lys824Glu/c.2470A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),5908,75,6021,"0,0124564026",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,"0,151",Tolerated,"34,84","33,52"
"low freq, many artifacts",UPN2_047,4,106157599,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys834Arg/c.2500T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),7872,85,8075,"0,0105263158",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,62",Deleterious,"0,012",Damaging,"35,29","33,44"
"low freq, many artifacts",UPN2_044,4,106157599,T,G,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys834Gly/c.2500T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),2974,60,3043,"0,0197173842",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,92",Deleterious,"0,132",Tolerated,"35,3","31,7"
"low freq, many artifacts",UPN2_047,4,106157599,T,G,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys834Gly/c.2500T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),7872,101,8075,"0,0125077399",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,92",Deleterious,"0,132",Tolerated,"35,29","31,47"
"low freq, many artifacts",UPN2_049,4,106157599,T,G,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys834Gly/c.2500T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),5797,90,5918,"0,0152078405",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,92",Deleterious,"0,132",Tolerated,"35,26","32,02"
"inspected, strandbias",UPN2_056,4,106157599,T,G,missense_variant(MODERATE|MISSENSE|Tgt/Ggt|p.Cys834Gly/c.2500T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),1051,33,1090,"0,0302752294",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,92",Deleterious,"0,132",Tolerated,"35,33","31,79"
"inspected, strandbias",UPN2_056,4,106157657,T,C,missense_variant(MODERATE|MISSENSE|cTt/cCt|p.Leu853Pro/c.2558T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),1204,53,1265,"0,0418972332",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,084",Tolerated,"34,66","32,25"
"low freq, many artifacts",UPN2_006,4,106157660,T,A,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe854Tyr/c.2561T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),9170,112,9314,"0,0120249087",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,96",Neutral,"0,015",Damaging,"34,81","30,58"
"low freq, many artifacts",UPN2_006,4,106157666,G,A,missense_variant(MODERATE|MISSENSE|gGa/gAa|p.Gly856Glu/c.2567G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),9192,106,9313,"0,0113819392",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,28",Tolerated,"34,83","34,81"
inspected,UPN2_056,4,106157702,T,C,missense_variant(MODERATE|MISSENSE|tTt/tCt|p.Phe868Ser/c.2603T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),2349,69,2428,"0,0284184514",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,96",Neutral,"0,002",Damaging,"31,57","33,87"
"inspected, bad alignment",UPN2_002,4,106157714,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val872Gly/c.2615T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),17062,2543,19725,"0,1289226869",1,1,0,1,0,1,0,0,4,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,"0,203",Tolerated,"34,56","33,37"
"inspected, bad alignment",UPN2_002,4,106157714,TGATCCCAAAGCAAGATCT,GGA,frameshift_variant+missense_variant(HIGH||gtgatcccaaagcaagatctt/gGGAt|p.Val872fs/c.2615_2633delTGATCCCAAAGCAAGATCTinsGGA|2002|TET2|protein_coding|CODING|ENST00000380013|3|GGA),17062,2543,19725,"0,1289226869",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,NA,NA
"inspected, bad alignment",UPN2_002,4,106157716,ATCCCAAAGCAAGATCT,A,frameshift_variant(HIGH||ccaaagcaagatcttctt/|p.Pro874fs/c.2620_2635delCCAAAGCAAGATCTTC|2002|TET2|protein_coding|CODING|ENST00000380013|3|A|INFO_REALIGN_3_PRIME),17087,2528,19709,"0,1282662743",1,1,0,1,0,1,0,0,4,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,14",NA
"inspected, low freq, many artifacts, many samples",UPN2_048,4,106157750,A,G,missense_variant(MODERATE|MISSENSE|cAa/cGa|p.Gln884Arg/c.2651A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),925,35,966,"0,0362318841",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,084",Tolerated,"31,34","29,2"
"low bq, bad alignment, many samples",UPN2_042,4,106157847,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln916His/c.2748G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),1729,149,1901,"0,0783798001",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"25,26","14,43"
"low bq, bad alignment, many samples",UPN2_047,4,106157847,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln916His/c.2748G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),1216,223,1457,"0,153054221",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"22,31","14,3"
"low bq, bad alignment, many samples",UPN2_048,4,106157847,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln916His/c.2748G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),665,140,816,"0,1715686275",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"21,04","14,29"
"low bq, bad alignment, many samples",UPN2_049,4,106157847,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln916His/c.2748G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),912,128,1060,"0,120754717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"24,1","14,36"
"low bq, bad alignment, many samples",UPN2_056,4,106157847,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln916His/c.2748G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),367,116,487,"0,2381930185",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"19,02","14,22"
"low bq, many samples",UPN2_059,4,106157847,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln916His/c.2748G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),580,34,626,"0,054313099",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"28,4","14,38"
"low bq, many samples",UPN2_064,4,106157847,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln916His/c.2748G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),778,20,818,"0,0244498778",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"28,65",15
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106157847,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln916His/c.2748G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),2031,38,2107,"0,018035121",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"29,85",15
low bq,UPN2_081,4,106157847,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln916His/c.2748G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),1091,85,1205,"0,0705394191",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"27,51","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_089,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),19484,327,19897,"0,0164346384",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"29,51","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),7630,90,7790,"0,0115532734",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"28,31","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_044,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),2501,51,2563,"0,0198985564",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"28,38","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_005,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),3399,36,3446,"0,010446895",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"30,71",14
"low bq, low freq, many artifacts, many samples",UPN2_045,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),13256,186,13543,"0,0137340323",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"28,45",15
"low bq, low freq, many artifacts, many samples",UPN2_046,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),9756,123,9995,"0,0123061531",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"28,25","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_050,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),12237,173,12529,"0,0138079655",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"28,35","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),15058,189,15344,"0,0123175182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"28,52","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_052,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),17999,243,18364,"0,0132324112",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"28,43","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_053,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),21680,291,22115,"0,0131584897",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"28,36","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_054,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),14241,190,14556,"0,0130530365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"28,37","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_055,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),11181,150,11450,"0,0131004367",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"28,23","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_090,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),15288,261,15624,"0,0167050691",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"29,39","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_057,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),17160,226,17521,"0,0128988071",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"28,48","14,12"
"low bq, low freq, many artifacts, many samples",UPN2_058,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),20186,266,20575,"0,0129283111",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"28,48","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_060,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),15496,315,15893,"0,0198200466",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"30,05","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_091,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),5820,108,5973,"0,0180813661",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"29,54","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_092,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),10693,177,10997,"0,0160952987",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"29,46","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_093,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),11466,200,11696,"0,0170998632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"29,69","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_061,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),22153,439,22718,"0,0193238841",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"29,98","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_062,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),20810,411,21324,"0,0192740574",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"29,96","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_063,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),18035,355,18474,"0,0192161957",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"30,06","14,63"
"low bq, many samples",UPN2_065,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),3034,69,3134,"0,0220165922",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"29,9","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_066,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),34102,661,34910,"0,0189344027",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"30,07","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_067,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),49148,1041,50431,"0,0206420654",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"30,12","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_068,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),33901,641,34711,"0,0184667685",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"30,01","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_069,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),35106,692,35968,"0,0192393238",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"30,02","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_070,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),21895,426,22406,"0,0190127644",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"30,04","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_071,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),15497,278,15865,"0,017522849",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"30,06","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),5863,115,6023,"0,019093475",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"29,86","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),2031,34,2107,"0,0161366872",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"29,85","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_074,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),14420,300,14797,"0,0202743799",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"30,03","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_075,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),27049,510,27694,"0,0184155413",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"30,09","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_076,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),27859,528,28522,"0,0185120258",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"30,02","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_077,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),31255,562,31961,"0,0175839304",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"29,94","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_078,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),24274,430,24827,"0,0173198534",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"29,93","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_079,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),13417,267,13740,"0,0194323144",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"30,08","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_080,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),8939,175,9174,"0,0190756486",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,30,"14,24"
"low bq, many samples",UPN2_081,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),1091,29,1205,"0,02406639",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"27,51","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_082,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),23635,465,24227,"0,0191934618",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"30,15","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_083,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),36517,673,37384,"0,0180023539",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"30,02","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_084,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),36598,720,37482,"0,0192092204",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"30,17","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_085,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),32507,638,33305,"0,0191562828",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"30,08","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_086,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),24406,469,24990,"0,018767507",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"29,98","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_087,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),31017,631,31810,"0,0198365294",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"30,13","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_088,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),29854,621,30638,"0,0202689471",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"30,06","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_094,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),17983,324,18362,"0,0176451367",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"29,45","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_095,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),17929,329,18345,"0,017934042",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"29,41","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_096,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),19475,373,19928,"0,0187173826",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"29,63","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_097,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),15663,299,16016,"0,0186688312",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"29,55","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_098,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),8320,126,8495,"0,0148322543",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"29,28","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_099,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),10395,176,10608,"0,0165912519",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"29,36","15,95"
"low bq, low freq, many artifacts, many samples",UPN2_100,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),16355,325,16730,"0,0194261805",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"29,73","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_101,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),16589,284,16959,"0,0167462704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"29,35","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_102,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),21085,358,21532,"0,0166264165",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"29,33","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_103,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),17769,316,18158,"0,0174027977",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"29,31","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_104,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),21204,399,21691,"0,0183947259",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"29,38","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_105,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),14341,295,14697,"0,0200721236",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"29,58","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_106,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),7531,121,7707,"0,015700013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"29,33","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_107,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),33632,583,34364,"0,0169654289",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"29,43","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_108,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),24975,442,25512,"0,0173251803",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"29,59","15,45"
"low bq, low freq, many artifacts, many samples",UPN2_109,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),27905,481,28496,"0,016879562",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"29,51","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_110,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),28816,486,29421,"0,0165188131",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"29,51","14,64"
"low bq, low freq, many artifacts",UPN2_111,4,106157847,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln916His/c.2748G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),25015,414,25536,"0,016212406",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,2,Damaging,"29,43","14,46"
"inspected, many artifacts",UPN2_042,4,106157851,A,G,missense_variant(MODERATE|MISSENSE|Agg/Ggg|p.Arg918Gly/c.2752A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),1864,39,1912,"0,0203974895",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,004",Damaging,"31,63","31,69"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106157853,G,C,missense_variant(MODERATE|MISSENSE|agG/agC|p.Arg918Ser/c.2754G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),1885,20,1916,"0,0104384134",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,198,Tolerated,"30,54",14
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106157853,G,C,missense_variant(MODERATE|MISSENSE|agG/agC|p.Arg918Ser/c.2754G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),1194,25,1222,"0,0204582651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,198,Tolerated,"29,98","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106157854,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr919Asn/c.2755T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),1876,22,1917,"0,011476265",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,2,Damaging,"29,51","14,59"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,4,106157854,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr919Asn/c.2755T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),1420,24,1476,"0,0162601626",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,2,Damaging,"26,2",14
"low bq, bad alignment, many samples",UPN2_048,4,106157854,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr919Asn/c.2755T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),809,20,841,"0,0237812128",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,2,Damaging,"24,58",14
"low bq, low freq, many artifacts",UPN2_049,4,106157854,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr919Asn/c.2755T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),1028,20,1073,"0,018639329",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,2,Damaging,"27,99",14
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106157857,T,A,missense_variant(MODERATE|MISSENSE|Ttg/Atg|p.Leu920Met/c.2758T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),1869,36,1921,"0,0187402395",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,18,Damaging,"30,62","18,78"
"low bq, many samples",UPN2_047,4,106157857,T,A,missense_variant(MODERATE|MISSENSE|Ttg/Atg|p.Leu920Met/c.2758T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),1433,35,1484,"0,0235849057",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,18,Damaging,"27,24","14,51"
"low bq, bad alignment, many samples",UPN2_048,4,106157857,T,A,missense_variant(MODERATE|MISSENSE|Ttg/Atg|p.Leu920Met/c.2758T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),819,22,845,"0,026035503",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,18,Damaging,"25,95","15,41"
"low bq, low freq, many artifacts",UPN2_049,4,106157857,T,A,missense_variant(MODERATE|MISSENSE|Ttg/Atg|p.Leu920Met/c.2758T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),1043,20,1075,"0,0186046512",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,18,Damaging,"29,4","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106157858,T,A,stop_gained(HIGH|NONSENSE|tTg/tAg|p.Leu920*/c.2759T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),1887,23,1921,"0,0119729308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,42","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106157858,T,A,stop_gained(HIGH|NONSENSE|tTg/tAg|p.Leu920*/c.2759T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),1441,32,1485,"0,0215488215",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,88","15,81"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106157858,T,A,stop_gained(HIGH|NONSENSE|tTg/tAg|p.Leu920*/c.2759T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),1044,21,1075,"0,0195348837",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,23","16,71"
"low bq, low freq, many artifacts",UPN2_065,4,106157858,T,A,stop_gained(HIGH|NONSENSE|tTg/tAg|p.Leu920*/c.2759T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),3112,32,3164,"0,01011378",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,79","26,34"
"low bq, low freq, many artifacts",UPN2_047,4,106157861,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile921Lys/c.2762T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),1460,22,1490,"0,0147651007",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,09",Neutral,"0,05",Damaging,"28,8","15,59"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106157865,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His922Gln/c.2766T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),1896,23,1928,"0,0119294606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,428,Tolerated,"30,15","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106157865,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His922Gln/c.2766T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),1468,23,1496,"0,0153743316",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,428,Tolerated,"28,84","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106157866,A,C,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn923His/c.2767A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),1892,24,1928,"0,0124481328",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,98",Neutral,137,Tolerated,"31,03",14
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106157866,A,C,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn923His/c.2767A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),1452,31,1496,"0,0207219251",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,98",Neutral,137,Tolerated,"28,45","14,58"
"low bq, low freq, many artifacts",UPN2_081,4,106157866,A,C,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn923His/c.2767A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),1201,24,1230,"0,0195121951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,98",Neutral,137,Tolerated,"31,22","17,12"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106157867,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn923Thr/c.2768A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),1882,24,1928,"0,0124481328",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,33,Damaging,"30,29","15,5"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106157867,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn923Thr/c.2768A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),1442,30,1497,"0,0200400802",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,33,Damaging,"28,31","15,3"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106157867,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn923Thr/c.2768A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),1051,23,1079,"0,0213160334",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,33,Damaging,29,"14,78"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106157867,A,T,missense_variant(MODERATE|MISSENSE|aAc/aTc|p.Asn923Ile/c.2768A>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),1442,21,1497,"0,0140280561",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,81,Tolerated,"28,31","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106157870,A,C,missense_variant(MODERATE|MISSENSE|cAt/cCt|p.His924Pro/c.2771A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),1898,21,1929,"0,0108864697",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,71",Neutral,86,Tolerated,"30,57",14
"low bq, low freq, many artifacts",UPN2_047,4,106157870,A,C,missense_variant(MODERATE|MISSENSE|cAt/cCt|p.His924Pro/c.2771A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),1469,26,1498,"0,0173564753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,71",Neutral,86,Tolerated,"28,28",14
"low bq, low freq, many artifacts",UPN2_045,4,106157875,A,T,missense_variant(MODERATE|MISSENSE|Aat/Tat|p.Asn926Tyr/c.2776A>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),13413,140,13618,"0,0102805111",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,12,Damaging,"33,3","24,04"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106157876,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn926Thr/c.2777A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),1880,36,1934,"0,0186142709",0,0,0,0,1,0,0,0,1,"0,0116",NO,NO,NO,O,NO,rs373958593,NO,"8,24E-006",NO,NO,"-0,33",Neutral,591,Tolerated,"30,69","15,19"
"low bq, many samples",UPN2_047,4,106157876,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn926Thr/c.2777A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),1437,52,1501,"0,034643571",0,0,0,0,1,0,0,0,1,"0,0116",NO,NO,NO,O,NO,rs373958593,NO,"8,24E-006",NO,NO,"-0,33",Neutral,591,Tolerated,"28,09","14,75"
"low bq, bad alignment, many samples",UPN2_048,4,106157876,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn926Thr/c.2777A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),823,28,858,"0,0326340326",0,0,0,0,1,0,0,0,1,"0,0116",NO,NO,NO,O,NO,rs373958593,NO,"8,24E-006",NO,NO,"-0,33",Neutral,591,Tolerated,"26,72","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106157876,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn926Thr/c.2777A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),1055,21,1085,"0,0193548387",0,0,0,0,1,0,0,0,1,"0,0116",NO,NO,NO,O,NO,rs373958593,NO,"8,24E-006",NO,NO,"-0,33",Neutral,591,Tolerated,"29,08","14,62"
"low bq, bad alignment",UPN2_056,4,106157876,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn926Thr/c.2777A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),481,21,504,"0,0416666667",0,0,0,0,1,0,0,0,1,"0,0116",NO,NO,NO,O,NO,rs373958593,NO,"8,24E-006",NO,NO,"-0,33",Neutral,591,Tolerated,"25,44",14
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106157879,T,A,missense_variant(MODERATE|MISSENSE|gTt/gAt|p.Val927Asp/c.2780T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),1873,24,1937,"0,0123902943",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,42",Neutral,6,Damaging,"29,14","15,29"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,4,106157879,T,A,missense_variant(MODERATE|MISSENSE|gTt/gAt|p.Val927Asp/c.2780T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),1441,31,1502,"0,0206391478",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,42",Neutral,6,Damaging,26,"14,42"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106157879,T,C,missense_variant(MODERATE|MISSENSE|gTt/gCt|p.Val927Ala/c.2780T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),1873,23,1937,"0,011874032",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,19",Neutral,1,Tolerated,"29,14","22,04"
"low bq, many samples",UPN2_042,4,106157882,T,A,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe928Tyr/c.2783T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),1887,44,1939,"0,0226921093",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,3",Neutral,488,Tolerated,"30,91","14,32"
"low bq, many samples",UPN2_047,4,106157882,T,A,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe928Tyr/c.2783T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),1450,48,1505,"0,0318936877",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,3",Neutral,488,Tolerated,"28,66","14,71"
"low bq, many samples",UPN2_048,4,106157882,T,A,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe928Tyr/c.2783T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),829,29,861,"0,0336817654",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,3",Neutral,488,Tolerated,"27,57","15,38"
"low bq, many samples",UPN2_049,4,106157882,T,A,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe928Tyr/c.2783T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),1048,32,1086,"0,02946593",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,3",Neutral,488,Tolerated,"29,63","14,62"
"low bq, bad alignment, many samples",UPN2_056,4,106157882,T,A,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe928Tyr/c.2783T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),481,23,505,"0,0455445545",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,3",Neutral,488,Tolerated,26,"14,57"
"low bq, low freq, many artifacts",UPN2_081,4,106157882,T,A,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe928Tyr/c.2783T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),1209,20,1234,"0,0162074554",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,3",Neutral,488,Tolerated,"31,33","18,55"
"low freq, many artifacts",UPN2_044,4,106157882,T,C,missense_variant(MODERATE|MISSENSE|tTt/tCt|p.Phe928Ser/c.2783T>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),2550,26,2583,"0,0100658149",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"0,08",Neutral,"0,834",Tolerated,"33,7","34,38"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106157888,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val930Glu/c.2789T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),1898,32,1941,"0,0164863472",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,5,Damaging,"30,26","15,66"
"low bq, many samples",UPN2_047,4,106157888,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val930Glu/c.2789T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),1428,70,1510,"0,0463576159",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,5,Damaging,"27,27","17,96"
"low bq, bad alignment, many samples",UPN2_048,4,106157888,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val930Glu/c.2789T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),825,33,862,"0,0382830626",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,5,Damaging,"25,58",14
low bq,UPN2_049,4,106157888,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val930Glu/c.2789T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),1045,29,1088,"0,0266544118",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,5,Damaging,"28,9","17,21"
"low freq, many artifacts",UPN2_006,4,106157905,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser936Arg/c.2806A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),2615,33,2661,"0,0124013529",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,"0,026",Damaging,"34,8","34,06"
"low bq, low freq, many artifacts",UPN2_081,4,106157907,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser936Arg/c.2808T>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),1196,21,1241,"0,0169218372",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,26,Damaging,"30,11","15,57"
"low freq, many artifacts",UPN2_044,4,106157909,A,G,missense_variant(MODERATE|MISSENSE|cAc/cGc|p.His937Arg/c.2810A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),2533,38,2581,"0,0147229756",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,"0,013",Damaging,"32,6","31,11"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106157917,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr940Pro/c.2818A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),1911,21,1942,"0,0108135942",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,63",Neutral,"0,11",Tolerated,"29,99",14
"low bq, low freq, many artifacts, many samples",UPN2_060,4,106157917,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr940Pro/c.2818A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),15675,207,15937,"0,0129886428",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,63",Neutral,"0,11",Tolerated,"30,13","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_061,4,106157917,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr940Pro/c.2818A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),22347,364,22826,"0,0159467274",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,63",Neutral,"0,11",Tolerated,"30,01","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_062,4,106157917,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr940Pro/c.2818A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),21037,297,21434,"0,0138564897",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,63",Neutral,"0,11",Tolerated,"29,99","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_063,4,106157917,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr940Pro/c.2818A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),18218,308,18585,"0,0165725047",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,63",Neutral,"0,11",Tolerated,"30,09","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_065,4,106157917,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr940Pro/c.2818A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),3096,45,3161,"0,0142360013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,63",Neutral,"0,11",Tolerated,"30,07","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_066,4,106157917,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr940Pro/c.2818A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),34471,494,35104,"0,0140724704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,63",Neutral,"0,11",Tolerated,"30,1","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_067,4,106157917,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr940Pro/c.2818A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),49841,718,50737,"0,0141514082",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,63",Neutral,"0,11",Tolerated,"30,18","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_068,4,106157917,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr940Pro/c.2818A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),34147,579,34895,"0,016592635",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,63",Neutral,"0,11",Tolerated,"29,96","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_069,4,106157917,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr940Pro/c.2818A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),35515,508,36170,"0,0140447885",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,63",Neutral,"0,11",Tolerated,"30,1","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_070,4,106157917,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr940Pro/c.2818A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),22139,323,22542,"0,0143288084",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,63",Neutral,"0,11",Tolerated,"30,05","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_071,4,106157917,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr940Pro/c.2818A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),15661,236,15964,"0,0147832623",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,63",Neutral,"0,11",Tolerated,"30,04","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106157917,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr940Pro/c.2818A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),5948,88,6085,"0,0144617913",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,63",Neutral,"0,11",Tolerated,"30,01","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106157917,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr940Pro/c.2818A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),2089,36,2139,"0,0168302945",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,63",Neutral,"0,11",Tolerated,"30,07","16,08"
"low bq, low freq, many artifacts, many samples",UPN2_074,4,106157917,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr940Pro/c.2818A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),14634,190,14871,"0,012776545",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,63",Neutral,"0,11",Tolerated,"30,01","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_075,4,106157917,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr940Pro/c.2818A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),27367,371,27834,"0,0133290221",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,63",Neutral,"0,11",Tolerated,"30,15","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_076,4,106157917,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr940Pro/c.2818A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),28135,430,28671,"0,0149977329",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,63",Neutral,"0,11",Tolerated,"30,04","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_077,4,106157917,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr940Pro/c.2818A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),31539,465,32138,"0,0144688531",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,63",Neutral,"0,11",Tolerated,"30,06","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_078,4,106157917,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr940Pro/c.2818A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),24464,389,24939,"0,0155980593",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,63",Neutral,"0,11",Tolerated,"30,01","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_079,4,106157917,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr940Pro/c.2818A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),13557,173,13775,"0,0125589837",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,63",Neutral,"0,11",Tolerated,"30,08","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_080,4,106157917,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr940Pro/c.2818A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),9049,133,9205,"0,0144486692",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,63",Neutral,"0,11",Tolerated,"30,09","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_082,4,106157917,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr940Pro/c.2818A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),23874,362,24348,"0,0148677509",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,63",Neutral,"0,11",Tolerated,"30,17","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_083,4,106157917,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr940Pro/c.2818A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),36828,588,37571,"0,0156503686",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,63",Neutral,"0,11",Tolerated,"30,07","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_084,4,106157917,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr940Pro/c.2818A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),36927,555,37640,"0,0147449522",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,63",Neutral,"0,11",Tolerated,"30,03","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_085,4,106157917,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr940Pro/c.2818A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),32869,490,33496,"0,0146286124",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,63",Neutral,"0,11",Tolerated,"30,08","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_086,4,106157917,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr940Pro/c.2818A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),24650,369,25115,"0,0146924149",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,63",Neutral,"0,11",Tolerated,"30,02","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_087,4,106157917,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr940Pro/c.2818A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),31382,496,31991,"0,0155043606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,63",Neutral,"0,11",Tolerated,"30,08","14,86"
"low bq, low freq, many artifacts",UPN2_088,4,106157917,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr940Pro/c.2818A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),30306,378,30829,"0,0122611827",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,63",Neutral,"0,11",Tolerated,"30,17","14,25"
"low freq, many artifacts",UPN2_004,4,106157940,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln947His/c.2841A>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),1259,21,1282,"0,0163806552",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,"0,104",Tolerated,"35,01","29,71"
"low bq, low freq, many artifacts",UPN2_050,4,106157941,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys948*/c.2842A>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),6243,71,6345,"0,0111899133",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,92","21,45"
many samples,UPN2_042,4,106157943,G,C,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys948Asn/c.2844G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),1284,32,1322,"0,0242057489",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,91",Neutral,1,Damaging,"32,02","28,62"
inspected,UPN2_048,4,106157943,G,C,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys948Asn/c.2844G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),740,52,797,"0,0652446675",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,91",Neutral,"0,001",Damaging,"30,43","30,42"
"low freq, many artifacts, many samples",UPN2_065,4,106157943,G,C,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys948Asn/c.2844G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),1598,20,1625,"0,0123076923",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,91",Neutral,1,Damaging,"34,69","31,1"
"low freq, many artifacts",UPN2_073,4,106157943,G,C,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys948Asn/c.2844G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),1134,21,1157,"0,0181503889",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,91",Neutral,"0,001",Damaging,"34,43","30,29"
many samples,UPN2_081,4,106157943,G,C,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys948Asn/c.2844G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),779,45,829,"0,0542822678",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,91",Neutral,1,Damaging,"32,54","30,16"
many samples,UPN2_001,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),13192,546,13771,"0,0396485368",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,11","31,34"
many samples,UPN2_014,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),21686,574,22310,"0,0257283729",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,34","31,52"
"many samples, strandbias",UPN2_015,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),30430,504,31013,"0,0162512495",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,36","31,62"
many samples,UPN2_016,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),14458,342,14849,"0,023031854",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,24","31,44"
"many samples, strandbias",UPN2_017,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),10321,282,10633,"0,0265212076",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,37","31,42"
"low freq, many artifacts, many samples",UPN2_018,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),14873,323,15232,"0,0212053571",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,34","31,44"
"many samples, strandbias",UPN2_019,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),17362,472,17866,"0,0264188962",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,28","31,69"
many samples,UPN2_020,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),13481,332,13839,"0,0239901727",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,34","31,1"
many samples,UPN2_021,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),14681,451,15178,"0,0297140598",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,14","31,62"
"many samples, strandbias",UPN2_002,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),15474,588,16101,"0,0365194708",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,15","31,49"
many samples,UPN2_003,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),3007,109,3123,"0,0349023375",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,19","31,57"
many samples,UPN2_022,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),21573,498,22135,"0,0224983059",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,1","31,55"
"many samples, strandbias",UPN2_023,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),25667,582,26317,"0,0221149827",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,35","31,43"
"low freq, many artifacts, many samples",UPN2_041,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),20739,280,21092,"0,0132751754",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"31,81","31,61"
"low freq, many artifacts, many samples",UPN2_024,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),12131,246,12407,"0,0198275167",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,39","31,59"
"low freq, many artifacts, many samples",UPN2_025,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),25825,576,26458,"0,021770353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,28","31,45"
many samples,UPN2_026,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),28584,743,29406,"0,0252669523",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,33","31,56"
many samples,UPN2_004,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),3971,192,4173,"0,0460100647",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"32,87","31,6"
"many samples, strandbias",UPN2_027,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),30625,787,31476,"0,025003177",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,35","31,35"
"many samples, strandbias",UPN2_042,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),26232,452,26775,"0,0168814192",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"31,91","31,71"
"many samples, strandbias",UPN2_028,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),21300,550,21900,"0,0251141553",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,33","31,61"
"inspected, bad alignment, strandbias, many samples",UPN2_043,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),19175,287,19524,"0,0146998566",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"32,35","30,95"
"low freq, many artifacts, many samples",UPN2_044,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),5026,71,5104,"0,0139106583",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"32,48","31,59"
many samples,UPN2_029,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),25643,627,26337,"0,0238068117",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,37","31,64"
"many samples, strandbias",UPN2_030,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),21608,552,22236,"0,0248246087",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,22","31,72"
many samples,UPN2_031,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),14449,357,14831,"0,0240712022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,07","31,66"
many samples,UPN2_005,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),4271,177,4456,"0,0397217235",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,05",32
many samples,UPN2_032,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),9504,220,9746,"0,0225733634",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,32","31,77"
"low freq, many artifacts, many samples",UPN2_046,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),22788,486,23369,"0,0207967821",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"32,4","30,93"
"many samples, strandbias",UPN2_033,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),19194,417,19663,"0,0212073437",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,28","31,48"
"many samples, strandbias",UPN2_034,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),7356,156,7520,"0,0207446809",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,36","31,54"
"many samples, strandbias",UPN2_047,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),30292,627,31056,"0,0201893354",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"31,88","31,38"
many samples,UPN2_048,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),25227,600,25917,"0,0231508276",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"31,85","31,56"
"many samples, strandbias",UPN2_035,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),33262,872,34219,"0,0254829188",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,03","31,52"
many samples,UPN2_036,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),34015,774,34871,"0,0221960942",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,33","31,49"
many samples,UPN2_006,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),13772,873,14711,"0,0593433485",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"32,14","31,6"
"low freq, many artifacts, many samples",UPN2_049,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),15651,300,15994,"0,0187570339",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"31,89","31,25"
"low freq, many artifacts, many samples",UPN2_037,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),30479,577,31148,"0,0185244639",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,31","31,57"
"many samples, strandbias",UPN2_038,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),40100,803,41020,"0,0195758167",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,34","31,24"
many samples,UPN2_039,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),32014,743,32867,"0,0226062616",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,28","31,45"
"low freq, many artifacts, many samples",UPN2_053,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),31168,466,31746,"0,0146790147",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"32,75","31,26"
"low freq, many artifacts, many samples",UPN2_054,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),22635,230,22955,"0,0100196036",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"32,63","31,1"
"many samples, strandbias",UPN2_007,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),35960,995,37062,"0,0268469052",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,06","31,51"
many samples,UPN2_008,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),47983,1197,49309,"0,0242754872",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,13","31,27"
many samples,UPN2_009,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),37281,854,38268,"0,0223162956",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,08","31,41"
many samples,UPN2_010,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),29353,862,30311,"0,0284385207",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"32,99","31,17"
many samples,UPN2_011,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),33264,1038,34376,"0,0301954852",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,33,"31,45"
"low freq, many artifacts, many samples",UPN2_055,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),27047,377,27502,"0,013708094",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"32,38","31,47"
"low freq, many artifacts, many samples",UPN2_056,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),9530,151,9704,"0,0155605936",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"31,83","31,4"
"low freq, many artifacts, many samples",UPN2_057,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),28779,356,29207,"0,0121888588",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"32,61","31,3"
"many samples, strandbias",UPN2_058,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),27706,463,28230,"0,0164009919",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"32,74","30,76"
many samples,UPN2_059,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),28309,1224,29611,"0,04133599",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"31,84","31,56"
many samples,UPN2_012,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),15386,488,15905,"0,0306821754",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"32,74","31,37"
many samples,UPN2_060,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),25582,954,26606,"0,0358565737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"32,59","31,31"
"low freq, many artifacts, many samples",UPN2_040,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),40260,866,41241,"0,0209985209",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,27","31,51"
"many samples, strandbias",UPN2_013,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),9801,253,10074,"0,0251141553",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,07","31,3"
"many samples, strandbias",UPN2_061,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),24434,764,25247,"0,0302610211",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,06","31,15"
"many samples, strandbias",UPN2_062,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),22854,739,23653,"0,0312433941",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,06","31,36"
many samples,UPN2_063,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),23174,917,24141,"0,0379851705",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"32,89","31,28"
many samples,UPN2_064,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),17691,1109,18848,"0,0588391341",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"31,86","31,44"
many samples,UPN2_065,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),18959,861,19888,"0,0432924377",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,32,"31,41"
"many samples, strandbias",UPN2_066,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),42777,1314,44212,"0,0297204379",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"32,88","31,25"
"many samples, strandbias",UPN2_067,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),51552,1372,53075,"0,025850212",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,11","31,08"
"inspected, bad alignment, strandbias, many samples",UPN2_068,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),34413,880,35401,"0,0248580549",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,19","31,02"
"many samples, strandbias",UPN2_069,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),37758,1049,38927,"0,0269478768",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,08","31,2"
many samples,UPN2_070,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),24178,663,24906,"0,0266200915",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,12","31,25"
many samples,UPN2_071,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),17588,616,18248,"0,0337571241",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,03","31,37"
many samples,UPN2_072,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),15431,756,16211,"0,0466350009",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"32,34","31,47"
"many samples, strandbias",UPN2_073,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),14400,554,14998,"0,0369382584",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"32,02","31,3"
"many samples, strandbias",UPN2_074,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),19743,576,20365,"0,0282838203",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"32,79","31,35"
many samples,UPN2_075,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),31738,875,32679,"0,0267756051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"32,99","30,94"
"many samples, strandbias",UPN2_076,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),31029,757,31871,"0,0237520003",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,06","30,98"
"many samples, strandbias",UPN2_077,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),33907,739,34733,"0,0212765957",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,1","30,96"
many samples,UPN2_078,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),27252,724,28046,"0,0258147329",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,05","31,2"
"many samples, strandbias",UPN2_079,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),16352,436,16822,"0,0259184401",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"32,94","31,12"
"many samples, strandbias",UPN2_080,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),20689,851,21595,"0,0394072702",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"32,38","31,57"
many samples,UPN2_081,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),23958,873,24887,"0,0350785551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"31,86","31,32"
"many samples, strandbias",UPN2_082,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),38272,937,39310,"0,023836174",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"32,68","31,05"
many samples,UPN2_083,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),37887,1174,39158,"0,0299811022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,17","31,28"
"low freq, many artifacts, many samples",UPN2_084,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),41420,889,42458,"0,0209383391",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,04","31,03"
"inspected, strandbias",UPN2_085,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),41365,956,42428,"0,02253229",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"32,89","31,07"
"many samples, strandbias",UPN2_086,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),33954,788,34847,"0,0226131374",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"32,77","31,36"
"many samples, strandbias",UPN2_087,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),40843,1032,41994,"0,0245749393",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"32,86","31,13"
"many samples, strandbias",UPN2_088,4,106157944,C,G,missense_variant(MODERATE|MISSENSE|Cat/Gat|p.His949Asp/c.2845C>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),33716,995,34785,"0,0286042835",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,0,Damaging,"33,02","30,99"
"low freq, many artifacts, many samples",UPN2_001,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),13557,196,13788,"0,0142152596",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,2,Damaging,"33,77","30,82"
"many samples, strandbias",UPN2_014,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),21917,314,22286,"0,014089563",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"33,78","30,61"
"low freq, many artifacts, many samples",UPN2_016,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),14636,173,14852,"0,0116482629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,2,Damaging,"33,73","31,14"
"many samples, strandbias",UPN2_017,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),10449,162,10639,"0,015226995",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"33,74","31,27"
"low freq, many artifacts, many samples",UPN2_018,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),15052,173,15258,"0,0113383143",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,2,Damaging,"33,71","31,61"
"low freq, many artifacts, many samples",UPN2_019,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),17628,229,17892,"0,0127990163",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,2,Damaging,"33,83","30,7"
"low freq, many artifacts, many samples",UPN2_020,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),13636,210,13868,"0,0151427747",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,2,Damaging,"33,79","31,17"
"many samples, strandbias",UPN2_021,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),15014,203,15255,"0,0133071124",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,34,"31,63"
"many samples, strandbias",UPN2_002,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),15857,262,16164,"0,0162088592",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"33,78","31,03"
"low freq, many artifacts, many samples",UPN2_003,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),3087,39,3131,"0,0124560843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,2,Damaging,"33,66","31,64"
"many samples, strandbias",UPN2_023,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),26046,294,26401,"0,0111359418",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"33,71","31,13"
"many samples, strandbias",UPN2_024,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),12218,138,12389,"0,0111389136",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"33,74","31,45"
"many samples, strandbias",UPN2_026,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),29108,331,29512,"0,0112157766",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"33,77","30,83"
"low freq, many artifacts, many samples",UPN2_004,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),4162,59,4231,"0,0139446939",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,2,Damaging,34,"31,39"
"low freq, many artifacts, many samples",UPN2_027,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),30976,467,31536,"0,0148084729",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,2,Damaging,"33,75","31,26"
"many samples, strandbias",UPN2_028,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),21662,279,22003,"0,0126800891",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"33,8","30,9"
"many samples, strandbias",UPN2_029,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),25977,397,26435,"0,0150179686",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"33,69","31,19"
"low freq, many artifacts, many samples",UPN2_030,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),21994,248,22298,"0,0111220737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,2,Damaging,"33,87","30,98"
"low freq, many artifacts, many samples",UPN2_005,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),4409,72,4484,"0,0160570919",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,2,Damaging,"33,75","30,6"
"low freq, many artifacts, many samples",UPN2_032,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),9658,110,9787,"0,0112393992",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,2,Damaging,"33,7","31,27"
"low freq, many artifacts, many samples",UPN2_033,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),19396,225,19672,"0,0114375763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,2,Damaging,"33,77","30,78"
"many samples, strandbias",UPN2_035,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),33851,381,34313,"0,0111036633",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"34,07","30,76"
"many samples, strandbias",UPN2_036,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),34343,534,34959,"0,0152750365",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"33,76","31,15"
"low freq, many artifacts",UPN2_037,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),30746,355,31165,"0,0113909835",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,2,Damaging,"33,81",31
"many samples, strandbias",UPN2_038,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),40451,517,41084,"0,0125839743",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"33,79","31,18"
"many samples, strandbias",UPN2_039,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),32340,475,32901,"0,0144372511",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"33,83","31,22"
"many samples, strandbias",UPN2_007,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),36609,485,37200,"0,0130376344",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"33,71","31,03"
"many samples, strandbias",UPN2_008,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),48604,681,49391,"0,0137879371",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"33,71","30,98"
"many samples, strandbias",UPN2_009,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),37806,404,38323,"0,0105419722",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"33,72","30,69"
"many samples, strandbias",UPN2_010,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),29844,376,30289,"0,0124137476",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"33,84","30,79"
"many samples, strandbias",UPN2_011,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),33963,484,34526,"0,0140184209",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"33,84","30,55"
"many samples, strandbias",UPN2_060,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),26369,323,26746,"0,0120765722",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"33,8","30,09"
"many samples, strandbias",UPN2_040,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),40612,584,41290,"0,0141438605",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"33,84","31,27"
"many samples, strandbias",UPN2_013,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),9958,145,10122,"0,0143252322",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"33,76","31,41"
"many samples, strandbias",UPN2_061,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),24756,481,25308,"0,019005848",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"33,32","30,75"
"many samples, strandbias",UPN2_062,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),23204,542,23811,"0,0227625887",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"33,37","30,95"
"many samples, strandbias",UPN2_063,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),23813,432,24295,"0,0177814365",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"33,54","30,39"
"many samples, strandbias",UPN2_066,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),43655,551,44306,"0,0124362389",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"33,53","30,58"
"many samples, strandbias",UPN2_067,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),52193,776,53098,"0,0146144864",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"33,25","30,64"
"inspected, bad alignment, strandbias, many samples",UPN2_068,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),34756,551,35394,"0,0155676103",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"33,25","30,66"
"many samples, strandbias",UPN2_069,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),38221,653,38970,"0,0167564793",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"33,29","30,9"
"many samples, strandbias",UPN2_070,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),24424,426,24901,"0,0171077467",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"33,31","30,73"
"many samples, strandbias",UPN2_071,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),17872,319,18228,"0,0175005486",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"33,38","31,02"
"many samples, strandbias",UPN2_074,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),20036,285,20378,"0,0139856708",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"33,64","30,54"
"many samples, strandbias",UPN2_075,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),32056,506,32652,"0,0154967536",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"33,39","30,25"
"many samples, strandbias",UPN2_076,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),31304,589,31966,"0,0184258274",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"33,39","30,81"
"many samples, strandbias",UPN2_077,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),34303,560,34926,"0,0160339002",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"33,34","30,77"
"many samples, strandbias",UPN2_078,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),27392,540,28020,"0,0192719486",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"33,44","30,79"
"many samples, strandbias",UPN2_079,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),16605,269,16907,"0,0159105696",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"33,49","30,79"
"many samples, strandbias",UPN2_080,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),21547,228,21806,"0,0104558378",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"34,08","30,02"
"many samples, strandbias",UPN2_083,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),38371,750,39193,"0,0191360702",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"33,25","30,61"
"many samples, strandbias",UPN2_084,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),41825,639,42556,"0,015015509",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"33,4","30,27"
"many samples, strandbias",UPN2_085,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),41882,546,42561,"0,0128286459",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"33,55","30,36"
"many samples, strandbias",UPN2_086,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),34457,384,34917,"0,0109975084",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"33,68","30,14"
"many samples, strandbias",UPN2_087,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),41433,561,42134,"0,0133146627",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"33,6","30,26"
"many samples, strandbias",UPN2_088,4,106157997,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln966His/c.2898G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),34240,550,34856,"0,0157792059",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,002",Damaging,"33,37","30,84"
"low freq, many artifacts",UPN2_044,4,106158047,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val983Glu/c.2948T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),7797,81,7897,"0,0102570596",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,12",Neutral,8,Damaging,"31,98","27,17"
"inspected, bad alignment, many artifacts",UPN2_044,4,106158077,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met993Lys/c.2978T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),7750,116,7890,"0,0147021546",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,"0,119",Tolerated,"33,7","29,34"
"low bq, low freq, many artifacts, many samples",UPN2_020,4,106158094,G,A,missense_variant(MODERATE|MISSENSE|Gaa/Aaa|p.Glu999Lys/c.2995G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),15226,168,15731,"0,0106795499",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,7,Damaging,"27,45","19,99"
"low bq, low freq, many artifacts, many samples",UPN2_041,4,106158094,G,A,missense_variant(MODERATE|MISSENSE|Gaa/Aaa|p.Glu999Lys/c.2995G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),40732,577,42696,"0,0135141465",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,7,Damaging,"28,23","17,61"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106158094,G,A,missense_variant(MODERATE|MISSENSE|Gaa/Aaa|p.Glu999Lys/c.2995G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),49308,631,51551,"0,0122403057",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,7,Damaging,"28,34","17,36"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106158094,G,A,missense_variant(MODERATE|MISSENSE|Gaa/Aaa|p.Glu999Lys/c.2995G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),29957,359,31328,"0,0114593973",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,7,Damaging,"28,28","17,11"
"low bq, low freq, many artifacts, many samples",UPN2_044,4,106158094,G,A,missense_variant(MODERATE|MISSENSE|Gaa/Aaa|p.Glu999Lys/c.2995G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),7527,86,7864,"0,0109359105",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,7,Damaging,"28,46","17,48"
"low bq, low freq, many artifacts, many samples",UPN2_045,4,106158094,G,A,missense_variant(MODERATE|MISSENSE|Gaa/Aaa|p.Glu999Lys/c.2995G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),37648,482,39389,"0,0122369189",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,7,Damaging,"28,36","16,76"
"low bq, low freq, many artifacts, many samples",UPN2_046,4,106158094,G,A,missense_variant(MODERATE|MISSENSE|Gaa/Aaa|p.Glu999Lys/c.2995G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),35488,425,37079,"0,0114620135",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,7,Damaging,"28,49","17,61"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106158094,G,A,missense_variant(MODERATE|MISSENSE|Gaa/Aaa|p.Glu999Lys/c.2995G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),57468,783,60205,"0,0130055643",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,7,Damaging,"28,23","17,31"
"low bq, low freq, many artifacts, many samples",UPN2_048,4,106158094,G,A,missense_variant(MODERATE|MISSENSE|Gaa/Aaa|p.Glu999Lys/c.2995G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),48589,707,50938,"0,0138796184",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,7,Damaging,"28,22","18,43"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106158094,G,A,missense_variant(MODERATE|MISSENSE|Gaa/Aaa|p.Glu999Lys/c.2995G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),29353,368,30655,"0,012004567",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,7,Damaging,"28,36","16,73"
"low bq, low freq, many artifacts, many samples",UPN2_050,4,106158094,G,A,missense_variant(MODERATE|MISSENSE|Gaa/Aaa|p.Glu999Lys/c.2995G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),35127,450,36701,"0,0122612463",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,7,Damaging,"28,48","17,6"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106158094,G,A,missense_variant(MODERATE|MISSENSE|Gaa/Aaa|p.Glu999Lys/c.2995G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),29630,452,31082,"0,0145421788",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,7,Damaging,"28,23","17,37"
"low bq, low freq, many artifacts, many samples",UPN2_052,4,106158094,G,A,missense_variant(MODERATE|MISSENSE|Gaa/Aaa|p.Glu999Lys/c.2995G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),30805,347,32105,"0,0108082853",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,7,Damaging,"28,5","17,26"
"low bq, low freq, many artifacts, many samples",UPN2_053,4,106158094,G,A,missense_variant(MODERATE|MISSENSE|Gaa/Aaa|p.Glu999Lys/c.2995G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),40029,489,41696,"0,0117277437",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,7,Damaging,"28,54","17,86"
"low bq, low freq, many artifacts, many samples",UPN2_054,4,106158094,G,A,missense_variant(MODERATE|MISSENSE|Gaa/Aaa|p.Glu999Lys/c.2995G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),30099,377,31451,"0,0119869003",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,7,Damaging,"28,57","17,24"
"low bq, low freq, many artifacts, many samples",UPN2_007,4,106158094,G,A,missense_variant(MODERATE|MISSENSE|Gaa/Aaa|p.Glu999Lys/c.2995G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),44545,472,45845,"0,0102955611",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,7,Damaging,"28,18","17,99"
"low bq, low freq, many artifacts, many samples",UPN2_010,4,106158094,G,A,missense_variant(MODERATE|MISSENSE|Gaa/Aaa|p.Glu999Lys/c.2995G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),38055,409,39151,"0,0104467319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,7,Damaging,"28,41","17,78"
"low bq, low freq, many artifacts, many samples",UPN2_055,4,106158094,G,A,missense_variant(MODERATE|MISSENSE|Gaa/Aaa|p.Glu999Lys/c.2995G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),41864,550,43779,"0,012563101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,7,Damaging,"28,39","18,21"
"low bq, low freq, many artifacts, many samples",UPN2_056,4,106158094,G,A,missense_variant(MODERATE|MISSENSE|Gaa/Aaa|p.Glu999Lys/c.2995G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),17711,217,18521,"0,01171643",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,7,Damaging,"28,29","16,55"
"low bq, low freq, many artifacts, many samples",UPN2_057,4,106158094,G,A,missense_variant(MODERATE|MISSENSE|Gaa/Aaa|p.Glu999Lys/c.2995G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),39271,527,41134,"0,0128117859",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,7,Damaging,"28,35","17,67"
"low bq, low freq, many artifacts, many samples",UPN2_058,4,106158094,G,A,missense_variant(MODERATE|MISSENSE|Gaa/Aaa|p.Glu999Lys/c.2995G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),34625,472,36277,"0,0130109987",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,7,Damaging,"28,19","18,53"
"low bq, low freq, many artifacts",UPN2_040,4,106158094,G,A,missense_variant(MODERATE|MISSENSE|Gaa/Aaa|p.Glu999Lys/c.2995G>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),46783,494,48292,"0,0102294376",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,7,Damaging,"27,68","22,03"
"low bq, low freq, many artifacts, many samples",UPN2_001,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),16667,261,17157,"0,0152124497",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"28,26","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_014,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),24638,482,25411,"0,0189681634",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,54","14,13"
"low bq, low freq, many artifacts, many samples",UPN2_015,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),34329,606,35256,"0,0171885636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"28,05","14,15"
"low bq, low freq, many artifacts, many samples",UPN2_016,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),16464,345,16983,"0,0203144321",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,25","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_017,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),11719,221,12070,"0,0183098592",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,64","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_018,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),16497,315,16988,"0,0185425006",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,52","14,13"
"low bq, low freq, many artifacts, many samples",UPN2_019,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),20177,390,20764,"0,0187825082",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,53","14,12"
"low bq, low freq, many artifacts, many samples",UPN2_020,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),15226,296,15731,"0,0188163499",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,45","14,07"
"low bq, low freq, many artifacts, many samples",UPN2_021,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),18405,411,19021,"0,0216076968",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,45","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_002,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),19077,254,19534,"0,0130029692",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"28,53","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_003,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),3676,53,3778,"0,0140285866",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"28,67","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_022,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),27195,555,28047,"0,0197882126",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,53","14,19"
"low bq, low freq, many artifacts, many samples",UPN2_023,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),28610,598,29523,"0,0202553941",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,69","14,18"
"low bq, many samples",UPN2_041,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),40732,1157,42696,"0,0270985572",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"28,23","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_024,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),13644,248,14050,"0,0176512456",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,87","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_025,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),29814,607,30733,"0,0197507565",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,56","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_026,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),32855,619,33802,"0,0183125259",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,78","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_004,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),5729,85,5891,"0,0144287897",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"28,51","14,15"
"low bq, low freq, many artifacts, many samples",UPN2_027,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),34720,678,35762,"0,0189586712",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,69","14,28"
"low bq, many samples",UPN2_089,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),21651,734,22554,"0,0325441163",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,93","14,26"
"low bq, many samples",UPN2_042,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),49308,1358,51551,"0,0263428449",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"28,34","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_028,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),24592,491,25343,"0,0193741862",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,85","14,4"
"low bq, many samples",UPN2_043,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),29957,837,31328,"0,0267173136",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"28,28","14,3"
"low bq, many samples",UPN2_044,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),7527,208,7864,"0,0264496439",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"28,46","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_029,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),28543,586,29435,"0,0199082725",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,66","14,15"
"low bq, low freq, many artifacts, many samples",UPN2_030,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),26127,539,26930,"0,0200148533",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,58","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_031,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),18677,387,19230,"0,020124805",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,74","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_005,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),5412,71,5558,"0,0127743793",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"28,42",14
"low bq, many samples",UPN2_045,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),37648,1050,39389,"0,0266571886",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"28,36","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_032,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),10689,222,11028,"0,0201305767",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,9","14,27"
"low bq, many samples",UPN2_046,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),35488,973,37079,"0,0262412686",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"28,49","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_033,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),22093,441,22792,"0,0193488943",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,84","14,19"
"low bq, low freq, many artifacts, many samples",UPN2_034,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),8363,158,8603,"0,0183656864",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,9","14,17"
"low bq, many samples",UPN2_047,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),57468,1582,60205,"0,0262768873",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"28,23","14,3"
"low bq, many samples",UPN2_048,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),48589,1353,50938,"0,0265617025",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"28,22","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_035,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),44095,883,45472,"0,0194185433",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,55","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_036,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),38489,735,39673,"0,0185264538",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,75","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_006,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),26206,381,26933,"0,0141462147",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"28,35","14,21"
"low bq, many samples",UPN2_049,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),29353,760,30655,"0,0247920405",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"28,36","14,31"
"low bq, many samples",UPN2_050,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),35127,945,36701,"0,0257486172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"28,48","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_037,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),34998,715,36068,"0,0198236664",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,76","14,28"
"low bq, many samples",UPN2_051,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),29630,828,31082,"0,0266392124",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"28,23","14,48"
"low bq, many samples",UPN2_052,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),30805,784,32105,"0,0244198723",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"28,5","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_038,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),45839,833,47205,"0,0176464358",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,71","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_039,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),37502,698,38560,"0,0181016598",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,82","14,26"
"low bq, many samples",UPN2_053,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),40029,969,41696,"0,0232396393",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"28,54","14,33"
"low bq, many samples",UPN2_054,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),30099,822,31451,"0,0261358939",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"28,57","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_007,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),44545,655,45845,"0,0142872723",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"28,18","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_008,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),57729,865,59335,"0,0145782422",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"28,36","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_009,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),45765,678,47078,"0,0144016313",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"28,31","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_010,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),38055,557,39151,"0,0142269674",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"28,41","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_011,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),43114,624,44290,"0,0140889591",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"28,32","14,33"
"low bq, many samples",UPN2_055,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),41864,1133,43779,"0,0258799881",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"28,39","14,33"
"low bq, many samples",UPN2_056,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),17711,506,18521,"0,0273203391",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"28,29","14,28"
"low bq, many samples",UPN2_090,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),19041,653,19841,"0,0329116476",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,94","14,23"
"low bq, many samples",UPN2_057,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),39271,1125,41134,"0,0273496378",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"28,35","14,42"
"low bq, many samples",UPN2_058,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),34625,976,36277,"0,026904099",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"28,19","14,37"
"low bq, many samples",UPN2_059,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),54112,4277,58893,"0,072623232",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,69","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_012,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),22178,360,22853,"0,0157528552",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"28,08","14,11"
"low bq, many samples",UPN2_060,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),34666,2598,37633,"0,0690351553",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,78","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_040,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),46783,919,48292,"0,0190300671",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,68","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_013,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),12284,186,12620,"0,0147385103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"28,29","14,08"
"low bq, many samples",UPN2_091,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),16805,631,17583,"0,0358869362",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,92","14,21"
"low bq, many samples",UPN2_092,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),11785,402,12289,"0,0327121816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"28,12","14,25"
"low bq, many samples",UPN2_093,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),12063,420,12579,"0,0333889816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,92","14,32"
"low bq, many samples",UPN2_061,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),25808,1941,27990,"0,0693461951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,79","14,71"
"low bq, many samples",UPN2_062,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),24417,1715,26433,"0,0648810199",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,86","14,65"
"low bq, many samples",UPN2_063,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),27711,2195,30198,"0,0726869329",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,79","14,61"
"low bq, many samples",UPN2_064,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),34066,2603,37023,"0,0703076466",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,7","14,64"
"low bq, many samples",UPN2_065,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),33921,2525,36842,"0,0685359101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,78","14,77"
"low bq, many samples",UPN2_066,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),49817,3540,53853,"0,0657344995",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,83","14,69"
"low bq, many samples",UPN2_067,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),51724,3891,56110,"0,0693459276",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,83","14,76"
"low bq, many samples",UPN2_068,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),33801,2259,36372,"0,0621082151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,95","14,67"
"low bq, many samples",UPN2_069,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),39064,2795,42194,"0,0662416457",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,91","14,68"
"low bq, many samples",UPN2_070,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),25569,1737,27541,"0,0630696053",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,95","14,73"
"low bq, many samples",UPN2_071,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),19178,1406,20760,"0,0677263969",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,87","14,63"
"low bq, many samples",UPN2_072,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),24597,1759,26593,"0,0661452262",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,82","14,75"
"low bq, many samples",UPN2_073,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),25680,1920,27884,"0,068856692",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,6","14,71"
"low bq, many samples",UPN2_074,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),23999,1727,25951,"0,0665484952",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,65","14,59"
"low bq, many samples",UPN2_075,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),34801,2676,37839,"0,070720685",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,66","14,69"
"low bq, many samples",UPN2_076,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),32957,2239,35472,"0,0631202075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,82","14,69"
"low bq, many samples",UPN2_077,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),34813,2630,37802,"0,0695730385",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,81","14,7"
"low bq, many samples",UPN2_078,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),29113,2096,31457,"0,0666306386",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,83","14,79"
"low bq, many samples",UPN2_079,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),18517,1424,20132,"0,0707331611",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,68","14,61"
"low bq, many samples",UPN2_080,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),31570,2428,34333,"0,0707191332",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,74","14,7"
"low bq, many samples",UPN2_081,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),44328,3614,48550,"0,074438723",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,75","14,7"
"low bq, many samples",UPN2_082,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),50575,3778,54877,"0,0688448713",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,74","14,71"
"low bq, many samples",UPN2_083,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),38139,2826,41314,"0,0684029627",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,84","14,61"
"low bq, many samples",UPN2_084,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),44194,3337,48006,"0,0695121443",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,86","14,63"
"low bq, many samples",UPN2_085,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),47967,3529,51952,"0,0679280875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,75","14,73"
"low bq, many samples",UPN2_086,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),41556,3038,44991,"0,067524616",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,78","14,67"
"low bq, many samples",UPN2_087,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),48468,3645,52624,"0,0692649742",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,71","14,69"
"low bq, many samples",UPN2_088,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),35934,2918,39220,"0,0744008159",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,69","14,82"
"low bq, many samples",UPN2_094,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),23315,760,24220,"0,0313790256",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,28,"14,19"
"low bq, many samples",UPN2_095,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),20560,647,21332,"0,0303300206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"28,06","14,3"
"low bq, many samples",UPN2_096,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),23607,816,24572,"0,03320853",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,92","14,37"
"low bq, many samples",UPN2_097,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),21988,755,22894,"0,0329780729",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,9","14,34"
"low bq, many samples",UPN2_098,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),22326,774,23288,"0,0332360014",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,97","14,2"
"low bq, many samples",UPN2_099,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),11233,366,11689,"0,0313114894",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"28,11","14,37"
"low bq, many samples",UPN2_100,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),20763,762,21690,"0,035131397",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,56","14,23"
"low bq, many samples",UPN2_101,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),19309,600,20036,"0,029946097",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"28,08","14,19"
"low bq, many samples",UPN2_102,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),22284,729,23187,"0,0314400311",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"28,17","14,24"
"low bq, many samples",UPN2_103,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),21619,694,22455,"0,030906257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"28,12","14,28"
"low bq, many samples",UPN2_104,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),25282,858,26339,"0,0325752686",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,98","14,4"
"low bq, many samples",UPN2_105,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),21912,761,22829,"0,0333347935",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,84","14,26"
"low bq, many samples",UPN2_106,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),35843,1244,37389,"0,0332718179",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,87","14,27"
"low bq, many samples",UPN2_107,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),39742,1298,41365,"0,0313791853",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"28,05","14,25"
"low bq, many samples",UPN2_108,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),31302,1039,32574,"0,0318966047",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,86","14,36"
"low bq, many samples",UPN2_109,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),35507,1185,36946,"0,0320738375",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"28,04","14,28"
"low bq, many samples",UPN2_110,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),35077,1164,36517,"0,0318755648",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"27,99","14,3"
low bq,UPN2_111,4,106158094,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu999Gln/c.2995G>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),29278,978,30419,"0,0321509583",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,59,Tolerated,"28,04","14,21"
"inspected, bad alignment, many artifacts",UPN2_044,4,106158106,TG,T,frameshift_variant(HIGH||tgg/|p.Trp1003fs/c.3009delG|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),3922,50,3986,"0,0125439037",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,56",NA
"inspected, many artifacts",UPN2_056,4,106158110,A,G,missense_variant(MODERATE|MISSENSE|aAa/aGa|p.Lys1004Arg/c.3011A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),9255,100,9381,"0,0106598444",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,007",Damaging,"35,45","34,71"
"low freq, many artifacts, many samples",UPN2_001,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),16963,361,17342,"0,0208165148",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,528,Tolerated,"35,36","34,94"
"many samples, strandbias",UPN2_014,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),24440,1024,25529,"0,040111246",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,51","35,47"
"many samples, strandbias",UPN2_015,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),33987,1416,35486,"0,0399030604",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,53","35,49"
"many samples, strandbias",UPN2_016,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),15840,743,16637,"0,0446594939",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,5","35,33"
"many samples, strandbias",UPN2_017,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),11782,582,12403,"0,0469241313",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,54","35,59"
"many samples, strandbias",UPN2_018,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),16770,789,17593,"0,0448473825",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,48","35,32"
"many samples, strandbias",UPN2_019,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),19643,850,20541,"0,0413806533",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,54","35,57"
"many samples, strandbias",UPN2_020,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),15204,654,15900,"0,0411320755",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,52","35,64"
"many samples, strandbias",UPN2_021,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),17751,762,18539,"0,0411025406",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,53","35,33"
"many samples, strandbias",UPN2_002,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),20251,679,20975,"0,0323718713",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,4","34,95"
many samples,UPN2_003,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),4205,121,4331,"0,0279381205",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,528,Tolerated,"35,34","35,21"
"many samples, strandbias",UPN2_022,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),27232,1298,28586,"0,0454068425",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,51","35,45"
"many samples, strandbias",UPN2_023,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),28759,1254,30082,"0,0416860581",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,47","35,37"
"many samples, strandbias",UPN2_024,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),13680,650,14369,"0,0452362725",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,53","35,37"
"many samples, strandbias",UPN2_025,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),29518,1389,30973,"0,0448455106",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,51","35,39"
"many samples, strandbias",UPN2_026,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),32439,1375,33896,"0,0405652584",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,52","35,27"
"many samples, strandbias",UPN2_004,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),6745,156,6921,"0,0225400954",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,31","34,46"
"many samples, strandbias",UPN2_027,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),34811,1265,36177,"0,034966968",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,51","35,26"
"many samples, strandbias",UPN2_089,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),21796,740,22585,"0,0327651096",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,55","35,58"
"many samples, strandbias",UPN2_042,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),50312,1716,52190,"0,032879862",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,29","35,2"
"many samples, strandbias",UPN2_028,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),24961,1069,26073,"0,0410002685",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,52","35,37"
many samples,UPN2_043,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),32189,1111,33404,"0,0332594899",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,528,Tolerated,"35,28",35
many samples,UPN2_044,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),6502,153,6667,"0,0229488526",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,528,Tolerated,"35,35","35,2"
"many samples, strandbias",UPN2_029,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),28735,1325,30136,"0,043967348",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,48","35,38"
many samples,UPN2_030,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),26296,1121,27477,"0,0407977581",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,528,Tolerated,"35,54","35,33"
many samples,UPN2_031,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),18410,853,19302,"0,0441923117",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,528,Tolerated,"35,51","35,43"
many samples,UPN2_005,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),6087,192,6286,"0,0305440662",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,528,Tolerated,"35,42","35,42"
"many samples, strandbias",UPN2_045,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),40631,1468,42252,"0,0347439174",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,26","35,11"
many samples,UPN2_032,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),11022,463,11512,"0,040218902",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,528,Tolerated,"35,52","35,53"
"many samples, strandbias",UPN2_046,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),37407,1185,38711,"0,0306114541",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,27","35,17"
"many samples, strandbias",UPN2_033,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),21872,1019,22940,"0,0444202267",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,53","35,26"
"many samples, strandbias",UPN2_034,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),8328,327,8680,"0,0376728111",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,55","35,25"
"many samples, strandbias",UPN2_047,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),60111,1492,61805,"0,0241404417",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,29","34,99"
"many samples, strandbias",UPN2_035,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),42838,1967,44905,"0,0438035853",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,54","35,39"
"many samples, strandbias",UPN2_036,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),39639,1195,40910,"0,029210462",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,51","35,27"
"many samples, strandbias",UPN2_006,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),27031,472,27547,"0,0171343522",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,39","35,09"
"many samples, strandbias",UPN2_049,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),30517,770,31378,"0,0245394863",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,27","35,08"
"many samples, strandbias",UPN2_050,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),36450,1280,37890,"0,0337820005",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,31","35,09"
"many samples, strandbias",UPN2_037,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),34769,1468,36327,"0,0404107138",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,53","35,26"
"many samples, strandbias",UPN2_051,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),29758,976,30845,"0,0316420814",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,3","35,4"
"many samples, strandbias",UPN2_052,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),32066,1113,33335,"0,0333883306",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,28","34,98"
"many samples, strandbias",UPN2_038,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),45437,2075,47624,"0,0435704687",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,53","35,33"
"many samples, strandbias",UPN2_039,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),37512,1528,39151,"0,0390283773",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,5","35,36"
"many samples, strandbias",UPN2_053,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),41450,1380,42953,"0,0321281401",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,32","35,19"
"many samples, strandbias",UPN2_054,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),30343,1051,31536,"0,0333269914",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,35","35,37"
"many samples, strandbias",UPN2_007,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),47706,1713,49502,"0,0346046624",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,33","35,19"
"many samples, strandbias",UPN2_008,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),61180,2251,63556,"0,0354175845",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,35","35,02"
"many samples, strandbias",UPN2_009,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),48706,1775,50600,"0,0350790514",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,3","34,99"
"many samples, strandbias",UPN2_010,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),39188,1027,40290,"0,0254901961",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,34",35
"many samples, strandbias",UPN2_011,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),45192,1803,47074,"0,0383013978",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,34","35,15"
"many samples, strandbias",UPN2_055,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),43950,1491,45613,"0,0326880495",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,28","35,25"
"many samples, strandbias",UPN2_056,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),17671,291,18020,"0,0161487236",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,3","34,54"
"many samples, strandbias",UPN2_090,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),19189,539,19763,"0,0272731873",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,54","35,47"
"many samples, strandbias",UPN2_057,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),40697,1834,42647,"0,0430041972",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,26","35,07"
"many samples, strandbias",UPN2_058,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),36007,790,36900,"0,0214092141",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,27","34,79"
"many samples, strandbias",UPN2_059,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),58871,2075,61125,"0,0339468303",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,21","35,21"
"many samples, strandbias",UPN2_012,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),23862,734,24642,"0,0297865433",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,28","34,81"
"many samples, strandbias",UPN2_060,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),37579,1270,38910,"0,0326394243",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,23","35,14"
"many samples, strandbias",UPN2_040,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),46876,1842,48822,"0,0377288927",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,51","35,23"
many samples,UPN2_013,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),13385,389,13794,"0,028200667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,528,Tolerated,"35,32","35,22"
"many samples, strandbias",UPN2_091,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),16298,499,16829,"0,0296511973",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,54","35,37"
"low freq, many artifacts, many samples",UPN2_092,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),11849,259,12136,"0,0213414634",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,528,Tolerated,"35,54","35,67"
"many samples, strandbias",UPN2_093,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),12006,367,12389,"0,0296230527",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,55","35,88"
"many samples, strandbias",UPN2_061,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),27586,984,28639,"0,0343587416",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,24","35,15"
"many samples, strandbias",UPN2_062,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),25347,736,26154,"0,0281410109",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,25","34,95"
"many samples, strandbias",UPN2_063,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),30186,1013,31254,"0,0324118513",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,23","35,13"
"many samples, strandbias",UPN2_064,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),36087,968,37128,"0,0260719672",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,23","35,15"
"many samples, strandbias",UPN2_065,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),38427,2127,40667,"0,05230285",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,21","35,16"
"many samples, strandbias",UPN2_066,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),56794,4121,61038,"0,0675153183",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,2","35,23"
"many samples, strandbias",UPN2_067,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),57296,4343,61793,"0,0702830418",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,21","35,28"
"inspected, bad alignment, strandbias, many samples",UPN2_068,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),37486,2070,39627,"0,0522371111",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,25","35,26"
"many samples, strandbias",UPN2_069,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),41744,1713,43562,"0,0393232634",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,22","35,1"
"many samples, strandbias",UPN2_070,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),27544,989,28594,"0,0345876757",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,21","35,25"
"many samples, strandbias",UPN2_071,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),21161,373,21582,"0,017282921",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,24","34,85"
"many samples, strandbias",UPN2_072,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),25848,545,26464,"0,0205940145",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,23",35
"many samples, strandbias",UPN2_073,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),27653,902,28627,"0,0315087155",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,24","35,34"
"many samples, strandbias",UPN2_074,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),26237,1538,27830,"0,0552641035",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,25","35,45"
"many samples, strandbias",UPN2_075,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),37433,1198,38723,"0,0309376856",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,23","35,1"
"many samples, strandbias",UPN2_076,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),35101,1434,36645,"0,0391322145",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,27","35,24"
"many samples, strandbias",UPN2_077,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),38543,1525,40182,"0,037952317",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,19","35,02"
"many samples, strandbias",UPN2_078,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),31765,790,32630,"0,0242108489",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,29",35
"many samples, strandbias",UPN2_079,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),20570,520,21139,"0,0245990823",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,22","35,01"
"many samples, strandbias",UPN2_080,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),34150,627,34854,"0,0179893269",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,22","35,3"
"many samples, strandbias",UPN2_081,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),47212,896,48228,"0,0185784192",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,2","34,6"
"many samples, strandbias",UPN2_082,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),54287,2686,57131,"0,0470147556",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,2","35,14"
"many samples, strandbias",UPN2_083,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),41978,1766,43849,"0,0402745787",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,23","35,11"
"many samples, strandbias",UPN2_084,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),47894,1717,49749,"0,0345132565",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,24","35,17"
"many samples, strandbias",UPN2_085,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),49305,2729,52197,"0,0522826982",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,25","35,11"
"many samples, strandbias",UPN2_086,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),40409,2909,43422,"0,0669936898",1,0,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,25","35,13"
"many samples, strandbias",UPN2_087,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),51540,2312,53978,"0,042832265",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,21","35,27"
"many samples, strandbias",UPN2_088,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),39053,1545,40687,"0,0379728169",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,2","35,27"
many samples,UPN2_094,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),21785,868,22698,"0,0382412547",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,528,Tolerated,"35,56","35,47"
"many samples, strandbias",UPN2_095,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),20086,688,20815,"0,0330530867",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,57","35,54"
"many samples, strandbias",UPN2_096,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),22266,877,23186,"0,0378245493",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,54","35,36"
"many samples, strandbias",UPN2_097,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),20800,852,21685,"0,0392898317",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,54","35,55"
"many samples, strandbias",UPN2_098,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),21196,716,21959,"0,0326062207",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,52","35,54"
"many samples, strandbias",UPN2_099,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),11204,444,11670,"0,0380462725",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,54","35,65"
"many samples, strandbias",UPN2_100,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),19720,848,20605,"0,0411550595",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,55","35,66"
many samples,UPN2_101,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),18613,717,19374,"0,0370083617",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,528,Tolerated,"35,6","35,51"
"many samples, strandbias",UPN2_102,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),21480,1043,22582,"0,0461872288",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,58","35,57"
"inspected, low freq, neutral effect",UPN2_103,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),20695,807,21552,"0,0374443207",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,528,Tolerated,"35,56","35,52"
"many samples, strandbias",UPN2_104,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),24301,997,25346,"0,0393355954",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,53","35,65"
"many samples, strandbias",UPN2_105,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),20545,791,21387,"0,0369850844",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,55","35,54"
"many samples, strandbias",UPN2_106,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),33218,1136,34420,"0,0330040674",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,54","35,55"
"many samples, strandbias",UPN2_107,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),39431,1676,41196,"0,0406835615",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,53","35,61"
"many samples, strandbias",UPN2_108,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),30303,1021,31386,"0,0325304276",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,53","35,5"
"many samples, strandbias",UPN2_109,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),34041,1362,35480,"0,0383878241",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,57","35,54"
"many samples, strandbias",UPN2_110,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),33309,1378,34776,"0,0396250288",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,53","35,59"
"many samples, strandbias",UPN2_111,4,106158139,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1014Ser/c.3040G>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),28368,1071,29486,"0,0363223225",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,rs145019756,NO,NO,NO,NO,"0,36",Neutral,"0,528",Tolerated,"35,55","35,35"
"low bq, low freq, many artifacts",UPN2_044,4,106158192,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1031Gln/c.3093T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),5112,58,5190,"0,0111753372",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,584,Tolerated,"29,43","16,48"
"low freq, many artifacts",UPN2_044,4,106158212,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1038Arg/c.3113A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),5104,61,5201,"0,0117285137",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,004",Damaging,"33,89","33,7"
"low freq, many artifacts",UPN2_044,4,106158224,A,T,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp1042Val/c.3125A>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),5106,69,5202,"0,0132641292",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,34",Deleterious,"0,001",Damaging,"32,57","30,93"
"low bq, low freq, many artifacts",UPN2_044,4,106158244,A,T,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys1049*/c.3145A>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),5040,134,5204,"0,0257494235",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,26","28,88"
"low bq, low freq, many artifacts, many samples",UPN2_041,4,106158286,A,T,missense_variant(MODERATE|MISSENSE|Aca/Tca|p.Thr1063Ser/c.3187A>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),18664,212,19003,"0,0111561332",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,39,Damaging,"34,46","23,79"
"low bq, low freq, many artifacts, many samples",UPN2_044,4,106158286,A,T,missense_variant(MODERATE|MISSENSE|Aca/Tca|p.Thr1063Ser/c.3187A>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),2538,26,2581,"0,0100736149",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,39,Damaging,"34,44","20,81"
"low bq, low freq, many artifacts, many samples",UPN2_048,4,106158286,A,T,missense_variant(MODERATE|MISSENSE|Aca/Tca|p.Thr1063Ser/c.3187A>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),23267,287,23675,"0,0121224921",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,39,Damaging,"34,44","25,9"
"low bq, low freq, many artifacts, many samples",UPN2_054,4,106158286,A,T,missense_variant(MODERATE|MISSENSE|Aca/Tca|p.Thr1063Ser/c.3187A>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),15028,158,15271,"0,0103464082",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,39,Damaging,"34,43","23,45"
"low bq, low freq, many artifacts",UPN2_055,4,106158286,A,T,missense_variant(MODERATE|MISSENSE|Aca/Tca|p.Thr1063Ser/c.3187A>T|2002|TET2|protein_coding|CODING|ENST00000380013|3|T),22512,252,22899,"0,0110048474",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,39,Damaging,"34,45","22,65"
"low freq, many artifacts",UPN2_044,4,106158287,C,A,missense_variant(MODERATE|MISSENSE|aCa/aAa|p.Thr1063Lys/c.3188C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),2578,27,2612,"0,0103369066",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,38",Deleterious,2,Damaging,"34,52",30
"many samples, low freq, many artifacts",UPN2_001,4,106158342,A,C,missense_variant(MODERATE|MISSENSE|ttA/ttC|p.Leu1081Phe/c.3243A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),13319,224,13629,"0,0164355419",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,"0,325",Tolerated,"33,12","31,53"
"low freq, many artifacts, many samples",UPN2_014,4,106158342,A,C,missense_variant(MODERATE|MISSENSE|ttA/ttC|p.Leu1081Phe/c.3243A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),20233,262,20623,"0,0127042622",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,325,Tolerated,"33,23","31,35"
"many samples, low freq, many artifacts",UPN2_017,4,106158342,A,C,missense_variant(MODERATE|MISSENSE|ttA/ttC|p.Leu1081Phe/c.3243A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),9512,116,9700,"0,0119587629",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,"0,325",Tolerated,"33,11","31,69"
"many samples, low freq, many artifacts",UPN2_020,4,106158342,A,C,missense_variant(MODERATE|MISSENSE|ttA/ttC|p.Leu1081Phe/c.3243A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),11650,171,11889,"0,0143830431",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,"0,325",Tolerated,"33,04","31,75"
"low freq, many artifacts, many samples",UPN2_021,4,106158342,A,C,missense_variant(MODERATE|MISSENSE|ttA/ttC|p.Leu1081Phe/c.3243A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),15263,174,15513,"0,0112163991",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,325,Tolerated,"33,38","31,29"
"many samples, low freq, many artifacts",UPN2_002,4,106158342,A,C,missense_variant(MODERATE|MISSENSE|ttA/ttC|p.Leu1081Phe/c.3243A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),16916,299,17310,"0,0172732525",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,"0,325",Tolerated,"33,11","31,52"
"low freq, many artifacts, many samples",UPN2_003,4,106158342,A,C,missense_variant(MODERATE|MISSENSE|ttA/ttC|p.Leu1081Phe/c.3243A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),3566,60,3641,"0,0164789893",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,325,Tolerated,"33,07","30,73"
"many samples, low freq, many artifacts",UPN2_026,4,106158342,A,C,missense_variant(MODERATE|MISSENSE|ttA/ttC|p.Leu1081Phe/c.3243A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),26597,303,27038,"0,0112064502",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,"0,325",Tolerated,"33,21","31,57"
"low freq, many artifacts, many samples",UPN2_004,4,106158342,A,C,missense_variant(MODERATE|MISSENSE|ttA/ttC|p.Leu1081Phe/c.3243A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),5443,117,5583,"0,020956475",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,325,Tolerated,"32,79","30,79"
"many samples, low freq, many artifacts",UPN2_027,4,106158342,A,C,missense_variant(MODERATE|MISSENSE|ttA/ttC|p.Leu1081Phe/c.3243A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),30399,360,30928,"0,0116399379",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,"0,325",Tolerated,"33,36","31,46"
"many samples, low freq, many artifacts",UPN2_028,4,106158342,A,C,missense_variant(MODERATE|MISSENSE|ttA/ttC|p.Leu1081Phe/c.3243A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),21789,225,22142,"0,0101616837",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,"0,325",Tolerated,"33,29","31,68"
"many samples, low freq, many artifacts",UPN2_029,4,106158342,A,C,missense_variant(MODERATE|MISSENSE|ttA/ttC|p.Leu1081Phe/c.3243A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),22703,278,23115,"0,0120268224",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,"0,325",Tolerated,"33,07","31,19"
"many samples, low freq, many artifacts",UPN2_030,4,106158342,A,C,missense_variant(MODERATE|MISSENSE|ttA/ttC|p.Leu1081Phe/c.3243A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),22488,232,22843,"0,0101562842",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,"0,325",Tolerated,"33,29","31,49"
"low freq, many artifacts, many samples",UPN2_005,4,106158342,A,C,missense_variant(MODERATE|MISSENSE|ttA/ttC|p.Leu1081Phe/c.3243A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),5338,80,5456,"0,0146627566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,325,Tolerated,"33,07","31,86"
"low freq, many artifacts, many samples",UPN2_032,4,106158342,A,C,missense_variant(MODERATE|MISSENSE|ttA/ttC|p.Leu1081Phe/c.3243A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),9247,100,9413,"0,0106236057",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,325,Tolerated,"33,17","31,49"
"many samples, low freq, many artifacts",UPN2_033,4,106158342,A,C,missense_variant(MODERATE|MISSENSE|ttA/ttC|p.Leu1081Phe/c.3243A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),19174,200,19479,"0,0102674675",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,"0,325",Tolerated,"33,35","31,68"
"low freq, many artifacts, many samples",UPN2_034,4,106158342,A,C,missense_variant(MODERATE|MISSENSE|ttA/ttC|p.Leu1081Phe/c.3243A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),6863,79,6980,"0,0113180516",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,325,Tolerated,"33,18","31,27"
"low freq, many artifacts, many samples",UPN2_006,4,106158342,A,C,missense_variant(MODERATE|MISSENSE|ttA/ttC|p.Leu1081Phe/c.3243A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),22456,383,22946,"0,0166913623",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,325,Tolerated,"33,19","31,65"
"many samples, low freq, many artifacts",UPN2_060,4,106158342,A,C,missense_variant(MODERATE|MISSENSE|ttA/ttC|p.Leu1081Phe/c.3243A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),35234,419,35803,"0,0117029299",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,"0,325",Tolerated,"33,29","31,44"
"many samples, low freq, many artifacts",UPN2_061,4,106158342,A,C,missense_variant(MODERATE|MISSENSE|ttA/ttC|p.Leu1081Phe/c.3243A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),26701,371,27222,"0,0136286827",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,"0,325",Tolerated,"33,41","31,29"
"many samples, low freq, many artifacts",UPN2_062,4,106158342,A,C,missense_variant(MODERATE|MISSENSE|ttA/ttC|p.Leu1081Phe/c.3243A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),24276,317,24695,"0,0128366066",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,"0,325",Tolerated,"33,46","31,4"
"low freq, many artifacts, many samples",UPN2_063,4,106158342,A,C,missense_variant(MODERATE|MISSENSE|ttA/ttC|p.Leu1081Phe/c.3243A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),30269,432,30837,"0,0140091449",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,325,Tolerated,"33,44","31,33"
"many samples, low freq, many artifacts",UPN2_064,4,106158342,A,C,missense_variant(MODERATE|MISSENSE|ttA/ttC|p.Leu1081Phe/c.3243A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),34973,496,35612,"0,0139278895",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,"0,325",Tolerated,"33,48","31,21"
"many samples, low freq, many artifacts",UPN2_065,4,106158342,A,C,missense_variant(MODERATE|MISSENSE|ttA/ttC|p.Leu1081Phe/c.3243A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),39129,519,39846,"0,0130251468",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,"0,325",Tolerated,"33,27","31,43"
"many samples, low freq, many artifacts",UPN2_066,4,106158342,A,C,missense_variant(MODERATE|MISSENSE|ttA/ttC|p.Leu1081Phe/c.3243A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),62280,872,63408,"0,0137522079",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,"0,325",Tolerated,"33,35","31,28"
"many samples, low freq, many artifacts",UPN2_067,4,106158342,A,C,missense_variant(MODERATE|MISSENSE|ttA/ttC|p.Leu1081Phe/c.3243A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),65305,769,66337,"0,011592324",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,"0,325",Tolerated,"33,5","31,22"
"low freq, many artifacts, many samples",UPN2_068,4,106158342,A,C,missense_variant(MODERATE|MISSENSE|ttA/ttC|p.Leu1081Phe/c.3243A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),40073,492,40746,"0,0120748049",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,325,Tolerated,"33,4","31,49"
"many samples, low freq, many artifacts",UPN2_069,4,106158342,A,C,missense_variant(MODERATE|MISSENSE|ttA/ttC|p.Leu1081Phe/c.3243A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),40568,612,41377,"0,0147908258",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,"0,325",Tolerated,"33,35","31,52"
"low freq, many artifacts",UPN2_070,4,106158342,A,C,missense_variant(MODERATE|MISSENSE|ttA/ttC|p.Leu1081Phe/c.3243A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),25974,378,26471,"0,0142797779",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,325,Tolerated,"33,28","31,41"
"many samples, low freq, many artifacts",UPN2_071,4,106158342,A,C,missense_variant(MODERATE|MISSENSE|ttA/ttC|p.Leu1081Phe/c.3243A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),21202,363,21648,"0,0167682927",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,"0,325",Tolerated,"33,42","30,83"
"many samples, low freq, many artifacts",UPN2_072,4,106158342,A,C,missense_variant(MODERATE|MISSENSE|ttA/ttC|p.Leu1081Phe/c.3243A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),25401,390,25897,"0,0150596594",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,"0,325",Tolerated,"33,46","31,56"
"many samples, low freq, many artifacts",UPN2_083,4,106158342,A,C,missense_variant(MODERATE|MISSENSE|ttA/ttC|p.Leu1081Phe/c.3243A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),41312,561,42056,"0,013339357",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,"0,325",Tolerated,"33,34","31,35"
"many samples, low freq, many artifacts",UPN2_088,4,106158342,A,C,missense_variant(MODERATE|MISSENSE|ttA/ttC|p.Leu1081Phe/c.3243A>C|2002|TET2|protein_coding|CODING|ENST00000380013|3|C),38167,450,38756,"0,0116111054",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,"0,325",Tolerated,"33,38","31,14"
"inspected, 4A, low freq",UPN2_103,4,106158364,GA,G,frameshift_variant(HIGH||aag/|p.Lys1090fs/c.3269delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|G|INFO_REALIGN_3_PRIME),6178,141,6334,"0,0222608147",0,0,0,1,1,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,06",NA
"many samples, low freq, many artifacts",UPN2_017,4,106158368,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1090Arg/c.3269A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),3510,36,3553,"0,0101322826",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,12",Neutral,"0,055",Tolerated,"35,34","35,78"
"many samples, low freq, many artifacts",UPN2_018,4,106158368,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1090Arg/c.3269A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),6307,74,6388,"0,0115842204",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,12",Neutral,"0,055",Tolerated,"35,34","34,3"
"many samples, low freq, many artifacts",UPN2_020,4,106158368,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1090Arg/c.3269A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),4041,57,4104,"0,0138888889",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,12",Neutral,"0,055",Tolerated,"35,37","33,98"
"many samples, low freq, many artifacts",UPN2_041,4,106158368,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1090Arg/c.3269A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),3593,46,3646,"0,0126165661",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,12",Neutral,"0,055",Tolerated,"34,97","33,33"
"many samples, low freq, many artifacts",UPN2_024,4,106158368,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1090Arg/c.3269A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),3755,46,3804,"0,0120925342",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,12",Neutral,"0,055",Tolerated,"35,37","35,09"
"low freq, many artifacts, many samples",UPN2_025,4,106158368,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1090Arg/c.3269A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),11260,116,11394,"0,0101807969",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,12",Neutral,55,Tolerated,"35,41","34,56"
"low freq, many artifacts, many samples",UPN2_026,4,106158368,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1090Arg/c.3269A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),10639,109,10755,"0,010134821",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,12",Neutral,55,Tolerated,"35,31","34,35"
"many samples, low freq, many artifacts",UPN2_089,4,106158368,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1090Arg/c.3269A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),7003,73,7080,"0,0103107345",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,12",Neutral,"0,055",Tolerated,"35,4","34,88"
"many samples, low freq, many artifacts",UPN2_042,4,106158368,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1090Arg/c.3269A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),12765,161,12947,"0,0124353132",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,12",Neutral,"0,055",Tolerated,"34,96","34,53"
"many samples, low freq, many artifacts",UPN2_028,4,106158368,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1090Arg/c.3269A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),9177,101,9291,"0,0108707351",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,12",Neutral,"0,055",Tolerated,"35,25","34,95"
"many samples, low freq, many artifacts",UPN2_043,4,106158368,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1090Arg/c.3269A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),7982,90,8086,"0,0111303488",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,12",Neutral,"0,055",Tolerated,"34,97","33,81"
"many samples, low freq, many artifacts",UPN2_030,4,106158368,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1090Arg/c.3269A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),9246,99,9356,"0,0105814451",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,12",Neutral,"0,055",Tolerated,"35,37","34,46"
"many samples, low freq, many artifacts",UPN2_045,4,106158368,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1090Arg/c.3269A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),6321,67,6400,"0,01046875",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,12",Neutral,"0,055",Tolerated,"34,94","33,93"
"many samples, low freq, many artifacts",UPN2_047,4,106158368,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1090Arg/c.3269A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),15549,168,15749,"0,010667344",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,12",Neutral,"0,055",Tolerated,"34,99","34,43"
"many samples, low freq, many artifacts",UPN2_048,4,106158368,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1090Arg/c.3269A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),11147,119,11284,"0,0105459057",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,12",Neutral,"0,055",Tolerated,"34,95","34,19"
"low freq, many artifacts, many samples",UPN2_036,4,106158368,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1090Arg/c.3269A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),12836,131,12988,"0,0100862334",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,12",Neutral,55,Tolerated,"35,29","35,31"
"many samples, low freq, many artifacts",UPN2_049,4,106158368,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1090Arg/c.3269A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),8204,110,8328,"0,0132084534",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,12",Neutral,"0,055",Tolerated,"34,97","34,02"
"many samples, low freq, many artifacts",UPN2_050,4,106158368,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1090Arg/c.3269A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),8814,110,8937,"0,0123083809",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,12",Neutral,"0,055",Tolerated,"34,97","34,14"
"many samples, low freq, many artifacts",UPN2_037,4,106158368,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1090Arg/c.3269A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),11077,113,11206,"0,0100838836",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,12",Neutral,"0,055",Tolerated,"35,3","35,35"
"many samples, low freq, many artifacts",UPN2_051,4,106158368,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1090Arg/c.3269A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),10699,121,10852,"0,0111500184",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,12",Neutral,"0,055",Tolerated,"35,02","34,41"
"many samples, low freq, many artifacts",UPN2_052,4,106158368,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1090Arg/c.3269A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),7936,87,8033,"0,0108303249",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,12",Neutral,"0,055",Tolerated,"34,99","34,67"
"low freq, many artifacts, many samples",UPN2_039,4,106158368,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1090Arg/c.3269A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),14720,149,14893,"0,0100047002",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,12",Neutral,55,Tolerated,"35,35","35,74"
"low freq, many artifacts, many samples",UPN2_053,4,106158368,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1090Arg/c.3269A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),13292,136,13450,"0,0101115242",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,12",Neutral,55,Tolerated,"34,92","34,53"
"many samples, low freq, many artifacts",UPN2_054,4,106158368,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1090Arg/c.3269A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),10182,124,10316,"0,0120201629",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,12",Neutral,"0,055",Tolerated,"34,92","34,52"
"many samples, low freq, many artifacts",UPN2_055,4,106158368,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1090Arg/c.3269A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),12431,170,12628,"0,0134621476",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,12",Neutral,"0,055",Tolerated,"34,9","34,56"
"many samples, low freq, many artifacts",UPN2_056,4,106158368,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1090Arg/c.3269A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),4768,66,4844,"0,0136251032",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,12",Neutral,"0,055",Tolerated,"34,93","34,55"
"many samples, low freq, many artifacts",UPN2_057,4,106158368,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1090Arg/c.3269A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),11766,148,11934,"0,0124015418",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,12",Neutral,"0,055",Tolerated,"34,87","34,46"
"many samples, low freq, many artifacts",UPN2_058,4,106158368,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1090Arg/c.3269A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),14833,205,15056,"0,0136158342",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,12",Neutral,"0,055",Tolerated,"34,93","34,26"
"many samples, low freq, many artifacts",UPN2_040,4,106158368,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1090Arg/c.3269A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),13126,137,13298,"0,0103023011",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,12",Neutral,"0,055",Tolerated,"35,37","35,08"
"many samples, low freq, many artifacts",UPN2_093,4,106158368,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1090Arg/c.3269A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),4514,53,4574,"0,0115872322",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,12",Neutral,"0,055",Tolerated,"35,49","35,36"
"many samples, low freq, many artifacts",UPN2_064,4,106158368,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1090Arg/c.3269A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),17977,197,18201,"0,0108235811",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,12",Neutral,"0,055",Tolerated,"34,87","34,18"
"many samples, low freq, many artifacts",UPN2_075,4,106158368,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1090Arg/c.3269A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),18125,185,18335,"0,0100899918",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,12",Neutral,"0,055",Tolerated,"34,97","34,94"
"many samples, low freq, many artifacts",UPN2_085,4,106158368,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1090Arg/c.3269A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),22626,234,22895,"0,0102205722",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,12",Neutral,"0,055",Tolerated,"34,92","33,83"
"many samples, low freq, many artifacts",UPN2_095,4,106158368,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1090Arg/c.3269A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),5586,65,5657,"0,0114901891",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,12",Neutral,"0,055",Tolerated,"35,43","34,38"
"many samples, low freq, many artifacts",UPN2_097,4,106158368,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1090Arg/c.3269A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),5403,62,5470,"0,0113345521",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,12",Neutral,"0,055",Tolerated,"35,32","34,87"
"many samples, low freq, many artifacts",UPN2_101,4,106158368,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1090Arg/c.3269A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),5924,62,5993,"0,010345403",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,12",Neutral,"0,055",Tolerated,"35,41","33,74"
"many samples, low freq, many artifacts",UPN2_102,4,106158368,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1090Arg/c.3269A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),6396,73,6474,"0,0112758727",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,12",Neutral,"0,055",Tolerated,"35,38","34,58"
"low freq, many artifacts",UPN2_107,4,106158368,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1090Arg/c.3269A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),10572,107,10687,"0,0100121643",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,12",Neutral,55,Tolerated,"35,37","35,07"
"many samples, low freq, many artifacts",UPN2_109,4,106158368,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1090Arg/c.3269A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),8777,91,8874,"0,0102546766",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,12",Neutral,"0,055",Tolerated,"35,43","35,19"
"many samples, low freq, many artifacts",UPN2_110,4,106158368,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1090Arg/c.3269A>G|2002|TET2|protein_coding|CODING|ENST00000380013|3|G),6603,69,6676,"0,0103355303",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,12",Neutral,"0,055",Tolerated,"35,42","34,81"
"low bq, low freq, many artifacts",UPN2_082,4,106158371,C,A,missense_variant(MODERATE|MISSENSE|aCa/aAa|p.Thr1091Lys/c.3272C>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),57771,608,58453,"0,0104015192",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,1,Damaging,"28,89","15,82"
"low bq, low freq, many artifacts, many samples",UPN2_001,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),10214,224,10470,"0,0213944604",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,38","16,54"
"low bq, many samples",UPN2_014,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),16146,486,16669,"0,0291559182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,27","15,4"
"low bq, many samples",UPN2_015,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),25190,665,25916,"0,025659824",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,98","15,75"
"low bq, many samples",UPN2_016,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),13069,405,13506,"0,0299866726",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,3","14,93"
"low bq, many samples",UPN2_017,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),6899,205,7116,"0,0288083193",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,54","15,49"
"low bq, many samples",UPN2_018,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),12398,352,12777,"0,027549503",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,73","15,41"
"low bq, many samples",UPN2_019,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),15482,435,15959,"0,027257347",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,81","15,4"
"low bq, many samples",UPN2_020,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),7952,255,8225,"0,0310030395",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,28","15,98"
"low bq, many samples",UPN2_021,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),13147,373,13546,"0,0275358039",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,37","15,31"
"low bq, many samples",UPN2_002,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),12932,301,13254,"0,0227101252",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,7","16,22"
"low bq, low freq, many artifacts, many samples",UPN2_003,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),2580,44,2628,"0,0167427702",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,86","16,3"
"low bq, many samples",UPN2_022,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),19632,564,20229,"0,0278807652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,51","15,24"
"low bq, many samples",UPN2_023,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),19626,540,20214,"0,0267141585",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,63","15,42"
"low bq, many samples",UPN2_041,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),6999,299,7309,"0,040908469",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"30,91","15,21"
"low bq, many samples",UPN2_024,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),7387,207,7610,"0,0272010512",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,44","16,06"
"low bq, many samples",UPN2_025,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),22085,645,22779,"0,0283155538",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,43","15,13"
"low bq, many samples",UPN2_026,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),20939,534,21526,"0,0248072099",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,88","15,41"
"low bq, low freq, many artifacts, many samples",UPN2_004,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),3402,76,3486,"0,0218014917",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,68","14,82"
"low bq, many samples",UPN2_027,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),26174,721,26928,"0,026775104",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,76","15,41"
"low bq, low freq, many artifacts, many samples",UPN2_089,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),13916,234,14169,"0,016514927",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"30,95","15,31"
"low bq, many samples",UPN2_042,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),24808,988,25862,"0,0382027685",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,1","15,38"
"low bq, many samples",UPN2_028,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),18110,480,18614,"0,025787042",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,98","15,84"
"low bq, many samples",UPN2_043,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),15473,632,16144,"0,039147671",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"30,93","15,59"
"low bq, many samples",UPN2_044,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),3796,143,3945,"0,0362484157",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,17","15,72"
"low bq, many samples",UPN2_029,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),16138,457,16620,"0,0274969916",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,74","15,52"
"low bq, many samples",UPN2_030,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),18201,519,18757,"0,02766967",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,63","15,48"
"low bq, many samples",UPN2_031,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),12216,387,12613,"0,030682629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,27","15,04"
"low bq, many samples",UPN2_005,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),4051,92,4147,"0,0221847118",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,54","14,85"
"low bq, many samples",UPN2_045,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),12255,500,12782,"0,039117509",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,1","15,44"
"low bq, many samples",UPN2_032,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),7165,239,7415,"0,0322319622",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,61","15,27"
"low bq, many samples",UPN2_046,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),27219,994,28251,"0,0351845952",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,19","15,47"
"low bq, many samples",UPN2_033,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),16426,482,16936,"0,028460085",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,3","15,21"
"low bq, many samples",UPN2_034,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),5339,160,5513,"0,0290223109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,58","14,71"
"low bq, many samples",UPN2_047,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),30130,1268,31484,"0,0402744251",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"30,97","15,98"
"low bq, many samples",UPN2_048,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),21664,906,22602,"0,0400849482",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"30,97","15,87"
"low bq, many samples",UPN2_035,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),30022,911,31001,"0,0293861488",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,32","15,29"
"low bq, many samples",UPN2_036,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),25207,737,26001,"0,0283450637",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,65","15,33"
"low bq, many samples",UPN2_006,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),18167,421,18624,"0,0226052405",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,57","15,39"
"low bq, many samples",UPN2_049,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),15953,654,16630,"0,0393265183",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,1","16,44"
"low bq, many samples",UPN2_050,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),17074,723,17850,"0,0405042017",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,11","15,42"
"low bq, many samples",UPN2_037,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),21671,658,22387,"0,0293920579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,68","15,56"
"low bq, many samples",UPN2_051,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),20699,861,21615,"0,039833449",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,01","16,2"
"low bq, many samples",UPN2_052,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),15376,600,16010,"0,0374765771",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,32","15,7"
"low bq, many samples",UPN2_038,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),32154,891,33119,"0,0269029862",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,75","15,31"
"low bq, many samples",UPN2_039,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),28954,743,29790,"0,0249412555",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,82","15,38"
"low bq, many samples",UPN2_053,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),25932,887,26880,"0,0329985119",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,25","15,83"
"low bq, many samples",UPN2_054,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),19777,768,20602,"0,0372779342",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,45","15,85"
"low bq, many samples",UPN2_007,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),33431,819,34326,"0,0238594651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,29","15,4"
"low bq, low freq, many artifacts, many samples",UPN2_008,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),40649,868,41586,"0,020872409",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,57","15,1"
"low bq, many samples",UPN2_009,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),31990,722,32764,"0,0220363814",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,53","15,66"
"low bq, many samples",UPN2_010,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),28265,651,28957,"0,0224816107",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,61","15,93"
"low bq, many samples",UPN2_011,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),27803,698,28550,"0,0244483363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,39","15,52"
"low bq, many samples",UPN2_055,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),24146,990,25189,"0,0393028703",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,09","15,64"
"low bq, many samples",UPN2_056,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),9283,355,9656,"0,0367647059",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,01","15,9"
"low bq, low freq, many artifacts, many samples",UPN2_090,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),10694,187,10914,"0,0171339564",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"30,95","14,83"
"low bq, many samples",UPN2_057,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),22843,965,23852,"0,0404578232",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,12","15,59"
"low bq, many samples",UPN2_058,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),28732,1232,30025,"0,0410324729",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"30,98","15,42"
"low bq, many samples",UPN2_059,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),52932,1680,54721,"0,0307011933",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"30,49","14,66"
"low bq, many samples",UPN2_012,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),14627,364,15023,"0,0242295147",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,33","14,83"
"low bq, many samples",UPN2_060,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),32833,1078,33998,"0,0317077475",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"30,55","14,76"
"low bq, many samples",UPN2_040,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),25779,766,26613,"0,0287829256",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,53","14,97"
"low bq, many samples",UPN2_013,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),8160,186,8350,"0,0222754491",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,54","16,72"
"low bq, low freq, many artifacts, many samples",UPN2_091,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),10328,172,10535,"0,0163265306",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"30,91","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_092,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),7088,113,7223,"0,0156444691",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,18","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_093,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),9032,115,9164,"0,0125491052",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,05","14,52"
"low bq, many samples",UPN2_061,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),25995,838,26870,"0,0311871976",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"30,64","15,17"
"low bq, many samples",UPN2_062,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),24414,712,25183,"0,0282730413",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"30,76","14,65"
"low bq, many samples",UPN2_063,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),29887,978,30932,"0,0316177421",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"30,61","14,73"
"low bq, many samples",UPN2_064,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),35253,1114,36417,"0,030590109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"30,54","14,81"
"low bq, many samples",UPN2_065,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),36168,1250,37481,"0,0333502308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"30,44","14,92"
"low bq, many samples",UPN2_066,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),59966,2043,62157,"0,0328683817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"30,45","14,84"
"low bq, many samples",UPN2_067,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),66389,2320,68837,"0,0337028052",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"30,34","14,84"
"low bq, many samples",UPN2_068,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),39650,1269,41000,"0,0309512195",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"30,62","14,82"
"low bq, many samples",UPN2_069,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),38764,1254,40111,"0,0312632445",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"30,62","14,72"
"low bq, many samples",UPN2_070,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),24021,779,24838,"0,0313632338",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"30,62","14,79"
"low bq, many samples",UPN2_071,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),21223,653,21927,"0,0297806357",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"30,48","14,76"
"low bq, many samples",UPN2_072,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),25672,875,26587,"0,0329108211",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"30,46","14,78"
"low bq, many samples",UPN2_073,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),25453,859,26382,"0,0325600788",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"30,42","14,6"
"low bq, many samples",UPN2_074,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),26551,902,27491,"0,0328107381",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"30,5","14,72"
"low bq, many samples",UPN2_075,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),35398,1158,36636,"0,0316082542",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"30,38","14,94"
"low bq, many samples",UPN2_076,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),32517,1032,33628,"0,0306887118",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"30,61","14,98"
"low bq, many samples",UPN2_077,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),36958,1187,38225,"0,0310529758",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"30,58","14,94"
"low bq, many samples",UPN2_078,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),29248,857,30181,"0,0283953481",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"30,75","14,62"
"low bq, many samples",UPN2_079,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),20417,668,21125,"0,0316213018",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"30,47","14,82"
"low bq, many samples",UPN2_080,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),29527,1011,30613,"0,0330251854",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"30,49","15,19"
"low bq, many samples",UPN2_081,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),41397,1420,42900,"0,0331002331",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"30,45","14,87"
"low bq, many samples",UPN2_082,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),56507,1895,58511,"0,0323870725",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"30,5","14,79"
"low bq, many samples",UPN2_083,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),39153,1161,40428,"0,0287177204",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"30,65","14,89"
"low bq, many samples",UPN2_084,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),44866,1468,46447,"0,0316059164",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"30,58","14,96"
"low bq, many samples",UPN2_085,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),44296,1378,45772,"0,0301057415",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"30,55","14,93"
"low bq, many samples",UPN2_086,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),38083,1180,39357,"0,02998196",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"30,76","14,91"
"low bq, many samples",UPN2_087,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),52258,1727,54070,"0,0319400777",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"30,47","14,8"
"low bq, many samples",UPN2_088,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),36400,1201,37685,"0,0318694441",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"30,49","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_094,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),9777,158,9948,"0,0158825895",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,25","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_095,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),11137,158,11326,"0,0139502031",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,29","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_096,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),9584,139,9758,"0,0142447223",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,07","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_097,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),10765,167,10947,"0,0152553211",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"30,97","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_098,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),12178,202,12406,"0,016282444",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,08","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_099,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),6309,99,6426,"0,0154061625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,21","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_100,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),10999,201,11231,"0,0178968925",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"30,84","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_101,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),11819,157,11995,"0,013088787",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,22","14,13"
"low bq, low freq, many artifacts, many samples",UPN2_102,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),12760,195,12978,"0,0150254276",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,25","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_103,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),12474,184,12687,"0,0145030346",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,51","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_104,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),12544,188,12763,"0,0147300791",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,08","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_105,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),10764,206,10997,"0,0187323816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,07","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_106,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),14489,246,14773,"0,0166520003",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,01","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_107,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),21052,318,21412,"0,0148514851",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,11","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_108,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),16650,263,16956,"0,0155107337",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,03","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_109,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),17469,256,17765,"0,0144103574",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,18","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_110,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),13139,194,13348,"0,0145340126",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,16","14,39"
"low bq, low freq, many artifacts",UPN2_111,4,106158438,T,A,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp1113Glu/c.3339T>A|2002|TET2|protein_coding|CODING|ENST00000380013|3|A),17315,279,17629,"0,0158261955",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,2,Damaging,"31,26","15,63"
"low freq, many artifacts, many samples",UPN2_001,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),5208,80,5309,"0,0150687512",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,38",NA
"low freq, many artifacts, many samples",UPN2_014,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),8306,95,8433,"0,0112652674",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,47",NA
"low freq, many artifacts, many samples",UPN2_015,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),12966,136,13143,"0,0103477136",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,52",NA
"low freq, many artifacts, many samples",UPN2_017,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),3547,40,3602,"0,0111049417",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,59",NA
"low freq, many artifacts, many samples",UPN2_018,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),6382,73,6470,"0,0112828439",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,51",NA
"low freq, many artifacts, many samples",UPN2_019,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),7944,92,8056,"0,0114200596",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,47",NA
"low freq, many artifacts, many samples",UPN2_021,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),6756,83,6855,"0,0121079504",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,54",NA
"low freq, many artifacts, many samples",UPN2_022,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),10098,114,10238,"0,0111349873",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,44",NA
"low freq, many artifacts, many samples",UPN2_023,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),10090,109,10233,"0,0106518128",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,47",NA
"low freq, many artifacts, many samples",UPN2_024,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),3802,43,3855,"0,011154345",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,42",NA
"low freq, many artifacts, many samples",UPN2_026,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),10743,112,10883,"0,01029128",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,55",NA
"low freq, many artifacts, many samples",UPN2_004,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),1733,21,1760,"0,0119318182",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,32",NA
"low freq, many artifacts, many samples",UPN2_027,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),13449,145,13632,"0,0106367371",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,44",NA
"low freq, many artifacts, many samples",UPN2_042,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),12988,155,13174,"0,0117655989",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,36",NA
"low freq, many artifacts, many samples",UPN2_028,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),9270,117,9419,"0,0124217008",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,39",NA
"low freq, many artifacts, many samples",UPN2_043,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),8101,84,8209,"0,0102326715",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,41",NA
"low freq, many artifacts, many samples",UPN2_044,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),1990,22,2017,"0,0109072881",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,39",NA
"low freq, many artifacts, many samples",UPN2_029,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),8287,103,8414,"0,0122415023",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,5",NA
"low freq, many artifacts, many samples",UPN2_030,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),9352,102,9484,"0,0107549557",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,49",NA
"low freq, many artifacts, many samples",UPN2_045,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),6398,69,6488,"0,0106350185",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,43",NA
"low freq, many artifacts, many samples",UPN2_046,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),14138,188,14362,"0,0130900989",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,39",NA
"low freq, many artifacts, many samples",UPN2_047,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),15809,163,16016,"0,0101773227",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,41",NA
"low freq, many artifacts, many samples",UPN2_048,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),11354,141,11531,"0,0122279074",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,35",NA
"low freq, many artifacts, many samples",UPN2_035,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),15432,191,15669,"0,0121896739",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,48",NA
"low freq, many artifacts, many samples",UPN2_036,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),12932,153,13128,"0,011654479",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,49",NA
"low freq, many artifacts, many samples",UPN2_006,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),9301,111,9441,"0,0117572291",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,38",NA
"low freq, many artifacts, many samples",UPN2_049,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),8306,114,8453,"0,0134863362",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,5",NA
"low freq, many artifacts, many samples",UPN2_037,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),11174,116,11327,"0,010241017",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,46",NA
"low freq, many artifacts, many samples",UPN2_051,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),10808,150,10990,"0,0136487716",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,44",NA
"low freq, many artifacts, many samples",UPN2_038,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),16544,183,16775,"0,0109090909",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,53",NA
"low freq, many artifacts, many samples",UPN2_039,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),14856,160,15067,"0,0106192341",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,48",NA
"low freq, many artifacts, many samples",UPN2_053,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),13483,147,13665,"0,0107574094",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,4",NA
"low freq, many artifacts, many samples",UPN2_007,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),17129,201,17381,"0,0115643519",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,32",NA
"low freq, many artifacts, many samples",UPN2_011,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),14242,167,14449,"0,0115578933",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,31",NA
"low freq, many artifacts, many samples",UPN2_055,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),12588,166,12785,"0,0129839656",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,4",NA
"low freq, many artifacts, many samples",UPN2_056,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),4840,53,4901,"0,0108141196",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,38",NA
"low freq, many artifacts, many samples",UPN2_058,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),15056,156,15260,"0,0102228047",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,39",NA
"low freq, many artifacts, many samples",UPN2_059,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),27408,286,27771,"0,0102985128",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,42",NA
"low freq, many artifacts, many samples",UPN2_012,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),7536,83,7641,"0,0108624526",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,29",NA
"low freq, many artifacts, many samples",UPN2_060,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),17025,178,17251,"0,0103182424",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,46",NA
"low freq, many artifacts, many samples",UPN2_040,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),13292,144,13475,"0,0106864564",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,48",NA
"low freq, many artifacts, many samples",UPN2_092,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),3599,44,3651,"0,0120514927",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,7",NA
"low freq, many artifacts, many samples",UPN2_093,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),4564,50,4617,"0,010829543",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,7",NA
"low freq, many artifacts, many samples",UPN2_061,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),13459,149,13639,"0,0109245546",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,44",NA
"low freq, many artifacts, many samples",UPN2_062,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),12621,159,12807,"0,0124150855",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,46",NA
"low freq, many artifacts, many samples",UPN2_064,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),18251,195,18493,"0,0105445304",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,39",NA
"low freq, many artifacts, many samples",UPN2_065,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),18761,209,19032,"0,0109815048",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,41",NA
"low freq, many artifacts, many samples",UPN2_066,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),31145,329,31560,"0,0104245881",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,42",NA
"low freq, many artifacts, many samples",UPN2_067,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),34514,369,34973,"0,0105509965",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,41",NA
"low freq, many artifacts, many samples",UPN2_069,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),20039,253,20347,"0,0124342655",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,42",NA
"low freq, many artifacts, many samples",UPN2_071,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),10985,123,11137,"0,0110442669",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,43",NA
"low freq, many artifacts, many samples",UPN2_072,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),13351,138,13514,"0,0102116324",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,38",NA
"low freq, many artifacts, many samples",UPN2_073,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),13185,147,13364,"0,0109997007",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,4",NA
"low freq, many artifacts, many samples",UPN2_074,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),13768,143,13945,"0,0102545715",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,41",NA
"low freq, many artifacts, many samples",UPN2_075,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),18285,248,18570,"0,0133548735",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,43",NA
"low freq, many artifacts, many samples",UPN2_076,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),16827,180,17056,"0,0105534709",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,44",NA
"low freq, many artifacts, many samples",UPN2_077,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),19087,226,19373,"0,0116657203",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,39",NA
"low freq, many artifacts, many samples",UPN2_078,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),15101,156,15289,"0,0102034142",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,39",NA
"low freq, many artifacts, many samples",UPN2_079,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),10564,119,10716,"0,0111048899",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,38",NA
"low freq, many artifacts, many samples",UPN2_080,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),15288,186,15522,"0,0119829919",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,36",NA
"low freq, many artifacts, many samples",UPN2_081,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),21451,267,21786,"0,012255577",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,41",NA
"low freq, many artifacts, many samples",UPN2_082,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),29322,328,29720,"0,0110363392",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,4",NA
"low freq, many artifacts, many samples",UPN2_083,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),20238,221,20506,"0,0107773335",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,41",NA
"low freq, many artifacts, many samples",UPN2_084,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),23271,254,23589,"0,0107677307",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,44",NA
"low freq, many artifacts, many samples",UPN2_085,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),22912,256,23231,"0,0110197581",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,38",NA
"low freq, many artifacts, many samples",UPN2_086,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),19707,210,19976,"0,0105126151",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,39",NA
"low freq, many artifacts, many samples",UPN2_087,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),27068,283,27447,"0,0103107808",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,4",NA
"low freq, many artifacts, many samples",UPN2_088,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),18891,210,19159,"0,0109609061",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,4",NA
"low freq, many artifacts, many samples",UPN2_094,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),4958,56,5019,"0,0111576011",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,71",NA
"low freq, many artifacts, many samples",UPN2_098,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),6181,64,6260,"0,0102236422",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,68",NA
"low freq, many artifacts, many samples",UPN2_103,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),6323,65,6393,"0,0101673706",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,7",NA
"low freq, many artifacts",UPN2_104,4,106158446,TA,T,frameshift_variant(HIGH||aat/|p.Asn1118fs/c.3353delA|2002|TET2|protein_coding|CODING|ENST00000380013|3|T|INFO_REALIGN_3_PRIME),6359,70,6438,"0,0108729419",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,69",NA
"low bq, low freq, many artifacts, many samples",UPN2_060,4,106162498,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln1138Lys/c.3412C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),13421,157,13594,"0,0115492129",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,63",Deleterious,84,Tolerated,"30,82","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_013,4,106162498,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln1138Lys/c.3412C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),4966,54,5025,"0,0107462687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,63",Deleterious,84,Tolerated,"32,73","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_061,4,106162498,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln1138Lys/c.3412C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),9908,114,10040,"0,0113545817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,63",Deleterious,84,Tolerated,"30,71","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_062,4,106162498,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln1138Lys/c.3412C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),8919,103,9040,"0,0113938053",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,63",Deleterious,84,Tolerated,"30,92","15,55"
"low bq, low freq, many artifacts, many samples",UPN2_065,4,106162498,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln1138Lys/c.3412C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),11701,140,11862,"0,0118023942",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,63",Deleterious,84,Tolerated,"30,67","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_066,4,106162498,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln1138Lys/c.3412C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),18150,197,18389,"0,0107129262",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,63",Deleterious,84,Tolerated,"30,65","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_067,4,106162498,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln1138Lys/c.3412C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),19877,245,20148,"0,0121600159",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,63",Deleterious,84,Tolerated,"30,54","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_068,4,106162498,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln1138Lys/c.3412C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),12654,137,12814,"0,0106914312",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,63",Deleterious,84,Tolerated,"30,86","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_069,4,106162498,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln1138Lys/c.3412C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),14687,154,14868,"0,0103578154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,63",Deleterious,84,Tolerated,"30,82","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_070,4,106162498,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln1138Lys/c.3412C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),8847,99,8960,"0,0110491071",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,63",Deleterious,84,Tolerated,"30,76","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106162498,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln1138Lys/c.3412C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),9409,96,9525,"0,0100787402",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,63",Deleterious,84,Tolerated,"30,63","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106162498,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln1138Lys/c.3412C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),9318,108,9452,"0,0114261532",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,63",Deleterious,84,Tolerated,"30,95","16,5"
"low bq, low freq, many artifacts, many samples",UPN2_077,4,106162498,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln1138Lys/c.3412C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),12752,131,12907,"0,0101495313",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,63",Deleterious,84,Tolerated,"30,7","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_078,4,106162498,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln1138Lys/c.3412C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),11667,123,11808,"0,0104166667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,63",Deleterious,84,Tolerated,"30,75","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_079,4,106162498,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln1138Lys/c.3412C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),7755,82,7849,"0,0104471907",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,63",Deleterious,84,Tolerated,"30,74","16,15"
"low bq, low freq, many artifacts, many samples",UPN2_080,4,106162498,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln1138Lys/c.3412C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),11422,127,11575,"0,0109719222",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,63",Deleterious,84,Tolerated,"30,78","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106162498,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln1138Lys/c.3412C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),15286,194,15503,"0,012513707",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,63",Deleterious,84,Tolerated,"30,61","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_082,4,106162498,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln1138Lys/c.3412C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),17940,190,18151,"0,0104677428",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,63",Deleterious,84,Tolerated,"30,61","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_084,4,106162498,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln1138Lys/c.3412C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),17458,200,17694,"0,0113032666",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,63",Deleterious,84,Tolerated,"30,9","15,31"
"low bq, low freq, many artifacts, many samples",UPN2_086,4,106162498,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln1138Lys/c.3412C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),10550,110,10683,"0,0102967331",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,63",Deleterious,84,Tolerated,"30,95","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_087,4,106162498,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln1138Lys/c.3412C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),18009,223,18259,"0,0122131552",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,63",Deleterious,84,Tolerated,"30,69","15,11"
"low bq, low freq, many artifacts",UPN2_088,4,106162498,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln1138Lys/c.3412C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),13539,167,13741,"0,0121534095",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,63",Deleterious,84,Tolerated,"30,76","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106162519,G,T,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly1145Cys/c.3433G>T|2002|TET2|protein_coding|CODING|ENST00000380013|4|T),9775,101,9894,"0,010208207",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,95",Deleterious,1,Damaging,"31,71","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_075,4,106162519,G,T,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly1145Cys/c.3433G>T|2002|TET2|protein_coding|CODING|ENST00000380013|4|T),14991,155,15181,"0,0102101311",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,95",Deleterious,1,Damaging,"31,51","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_060,4,106162520,G,T,missense_variant(MODERATE|MISSENSE|gGt/gTt|p.Gly1145Val/c.3434G>T|2002|TET2|protein_coding|CODING|ENST00000380013|4|T),26337,282,26671,"0,0105732818",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,95",Deleterious,1,Damaging,"28,61","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_061,4,106162520,G,T,missense_variant(MODERATE|MISSENSE|gGt/gTt|p.Gly1145Val/c.3434G>T|2002|TET2|protein_coding|CODING|ENST00000380013|4|T),19518,200,19751,"0,0101260696",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,95",Deleterious,1,Damaging,"28,65","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_062,4,106162520,G,T,missense_variant(MODERATE|MISSENSE|gGt/gTt|p.Gly1145Val/c.3434G>T|2002|TET2|protein_coding|CODING|ENST00000380013|4|T),17501,204,17750,"0,0114929577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,95",Deleterious,1,Damaging,"28,66","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_063,4,106162520,G,T,missense_variant(MODERATE|MISSENSE|gGt/gTt|p.Gly1145Val/c.3434G>T|2002|TET2|protein_coding|CODING|ENST00000380013|4|T),18208,191,18428,"0,0103646625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,95",Deleterious,1,Damaging,"28,56","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_064,4,106162520,G,T,missense_variant(MODERATE|MISSENSE|gGt/gTt|p.Gly1145Val/c.3434G>T|2002|TET2|protein_coding|CODING|ENST00000380013|4|T),19069,202,19330,"0,0104500776",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,95",Deleterious,1,Damaging,"28,61","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_065,4,106162520,G,T,missense_variant(MODERATE|MISSENSE|gGt/gTt|p.Gly1145Val/c.3434G>T|2002|TET2|protein_coding|CODING|ENST00000380013|4|T),22983,262,23293,"0,0112480144",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,95",Deleterious,1,Damaging,"28,52","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_066,4,106162520,G,T,missense_variant(MODERATE|MISSENSE|gGt/gTt|p.Gly1145Val/c.3434G>T|2002|TET2|protein_coding|CODING|ENST00000380013|4|T),35598,421,36097,"0,0116630191",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,95",Deleterious,1,Damaging,"28,6","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_067,4,106162520,G,T,missense_variant(MODERATE|MISSENSE|gGt/gTt|p.Gly1145Val/c.3434G>T|2002|TET2|protein_coding|CODING|ENST00000380013|4|T),39048,447,39577,"0,0112944387",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,95",Deleterious,1,Damaging,"28,53","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_068,4,106162520,G,T,missense_variant(MODERATE|MISSENSE|gGt/gTt|p.Gly1145Val/c.3434G>T|2002|TET2|protein_coding|CODING|ENST00000380013|4|T),24785,269,25104,"0,0107154238",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,95",Deleterious,1,Damaging,"28,63","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_069,4,106162520,G,T,missense_variant(MODERATE|MISSENSE|gGt/gTt|p.Gly1145Val/c.3434G>T|2002|TET2|protein_coding|CODING|ENST00000380013|4|T),28854,301,29222,"0,0103004586",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,95",Deleterious,1,Damaging,"28,59","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_070,4,106162520,G,T,missense_variant(MODERATE|MISSENSE|gGt/gTt|p.Gly1145Val/c.3434G>T|2002|TET2|protein_coding|CODING|ENST00000380013|4|T),17340,186,17568,"0,0105874317",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,95",Deleterious,1,Damaging,"28,66","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_071,4,106162520,G,T,missense_variant(MODERATE|MISSENSE|gGt/gTt|p.Gly1145Val/c.3434G>T|2002|TET2|protein_coding|CODING|ENST00000380013|4|T),16763,175,16973,"0,0103104931",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,95",Deleterious,1,Damaging,"28,66","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106162520,G,T,missense_variant(MODERATE|MISSENSE|gGt/gTt|p.Gly1145Val/c.3434G>T|2002|TET2|protein_coding|CODING|ENST00000380013|4|T),18489,199,18720,"0,0106303419",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,95",Deleterious,1,Damaging,"28,59","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106162520,G,T,missense_variant(MODERATE|MISSENSE|gGt/gTt|p.Gly1145Val/c.3434G>T|2002|TET2|protein_coding|CODING|ENST00000380013|4|T),18332,199,18581,"0,0107098649",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,95",Deleterious,1,Damaging,"28,56","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_075,4,106162520,G,T,missense_variant(MODERATE|MISSENSE|gGt/gTt|p.Gly1145Val/c.3434G>T|2002|TET2|protein_coding|CODING|ENST00000380013|4|T),28414,299,28784,"0,0103877154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,95",Deleterious,1,Damaging,"28,49","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_077,4,106162520,G,T,missense_variant(MODERATE|MISSENSE|gGt/gTt|p.Gly1145Val/c.3434G>T|2002|TET2|protein_coding|CODING|ENST00000380013|4|T),25067,283,25397,"0,0111430484",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,95",Deleterious,1,Damaging,"28,51","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_079,4,106162520,G,T,missense_variant(MODERATE|MISSENSE|gGt/gTt|p.Gly1145Val/c.3434G>T|2002|TET2|protein_coding|CODING|ENST00000380013|4|T),15228,161,15413,"0,0104457276",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,95",Deleterious,1,Damaging,"28,6","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106162520,G,T,missense_variant(MODERATE|MISSENSE|gGt/gTt|p.Gly1145Val/c.3434G>T|2002|TET2|protein_coding|CODING|ENST00000380013|4|T),29992,367,30418,"0,0120652245",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,95",Deleterious,1,Damaging,"28,52","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_082,4,106162520,G,T,missense_variant(MODERATE|MISSENSE|gGt/gTt|p.Gly1145Val/c.3434G>T|2002|TET2|protein_coding|CODING|ENST00000380013|4|T),35175,393,35639,"0,0110272454",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,95",Deleterious,1,Damaging,"28,62","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_084,4,106162520,G,T,missense_variant(MODERATE|MISSENSE|gGt/gTt|p.Gly1145Val/c.3434G>T|2002|TET2|protein_coding|CODING|ENST00000380013|4|T),34272,380,34727,"0,0109424943",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,95",Deleterious,1,Damaging,"28,61","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_085,4,106162520,G,T,missense_variant(MODERATE|MISSENSE|gGt/gTt|p.Gly1145Val/c.3434G>T|2002|TET2|protein_coding|CODING|ENST00000380013|4|T),29057,310,29429,"0,0105338272",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,95",Deleterious,1,Damaging,"28,57","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_086,4,106162520,G,T,missense_variant(MODERATE|MISSENSE|gGt/gTt|p.Gly1145Val/c.3434G>T|2002|TET2|protein_coding|CODING|ENST00000380013|4|T),20728,221,21001,"0,0105233084",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,95",Deleterious,1,Damaging,"28,71","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_087,4,106162520,G,T,missense_variant(MODERATE|MISSENSE|gGt/gTt|p.Gly1145Val/c.3434G>T|2002|TET2|protein_coding|CODING|ENST00000380013|4|T),35389,397,35860,"0,011070831",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,95",Deleterious,1,Damaging,"28,6","14,73"
"low bq, low freq, many artifacts",UPN2_088,4,106162520,G,T,missense_variant(MODERATE|MISSENSE|gGt/gTt|p.Gly1145Val/c.3434G>T|2002|TET2|protein_coding|CODING|ENST00000380013|4|T),26686,293,27019,"0,0108442207",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,95",Deleterious,1,Damaging,"28,53","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_059,4,106162522,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro1146Thr/c.3436C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),27757,284,28133,"0,0100949063",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,22",Deleterious,31,Damaging,"28,38","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_060,4,106162522,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro1146Thr/c.3436C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),26388,280,26757,"0,0104645513",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,22",Deleterious,31,Damaging,"28,35","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_066,4,106162522,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro1146Thr/c.3436C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),35698,370,36192,"0,0102232538",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,22",Deleterious,31,Damaging,"28,3","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_067,4,106162522,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro1146Thr/c.3436C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),39086,423,39672,"0,0106624319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,22",Deleterious,31,Damaging,"28,22",15
"low bq, low freq, many artifacts, many samples",UPN2_068,4,106162522,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro1146Thr/c.3436C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),24848,271,25185,"0,0107603732",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,22",Deleterious,31,Damaging,"28,41","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_070,4,106162522,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro1146Thr/c.3436C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),17348,187,17628,"0,0106081234",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,22",Deleterious,31,Damaging,"28,44","15,48"
"low bq, low freq, many artifacts, many samples",UPN2_079,4,106162522,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro1146Thr/c.3436C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),15244,160,15464,"0,0103466115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,22",Deleterious,31,Damaging,"28,37","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106162522,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro1146Thr/c.3436C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),30005,345,30466,"0,011324099",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,22",Deleterious,31,Damaging,"28,31","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_082,4,106162522,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro1146Thr/c.3436C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),35167,395,35688,"0,0110681462",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,22",Deleterious,31,Damaging,"28,24","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_084,4,106162522,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro1146Thr/c.3436C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),34355,377,34836,"0,010822138",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,22",Deleterious,31,Damaging,"28,39","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_085,4,106162522,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro1146Thr/c.3436C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),29066,300,29494,"0,0101715603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,22",Deleterious,31,Damaging,"28,37","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_086,4,106162522,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro1146Thr/c.3436C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),20751,215,21037,"0,0102200884",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,22",Deleterious,31,Damaging,"28,47","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_087,4,106162522,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro1146Thr/c.3436C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),35399,406,35952,"0,0112928349",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,22",Deleterious,31,Damaging,"28,33","15,11"
"low bq, low freq, many artifacts",UPN2_088,4,106162522,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro1146Thr/c.3436C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),26722,286,27086,"0,0105589603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,22",Deleterious,31,Damaging,"28,36","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_059,4,106162523,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1146His/c.3437C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),27732,328,28165,"0,0116456595",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"27,65","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_060,4,106162523,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1146His/c.3437C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),26370,287,26791,"0,0107125527",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"27,66","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_062,4,106162523,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1146His/c.3437C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),17558,192,17824,"0,0107719928",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"27,65","15,4"
"low bq, low freq, many artifacts, many samples",UPN2_063,4,106162523,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1146His/c.3437C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),18161,208,18472,"0,0112602858",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"27,63","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_064,4,106162523,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1146His/c.3437C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),19074,219,19383,"0,0112985606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"27,65","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_065,4,106162523,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1146His/c.3437C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),22976,279,23363,"0,0119419595",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"27,54","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_066,4,106162523,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1146His/c.3437C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),35637,405,36232,"0,0111779642",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"27,56","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_067,4,106162523,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1146His/c.3437C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),39089,456,39712,"0,0114826753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"27,48","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_068,4,106162523,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1146His/c.3437C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),24805,283,25213,"0,0112243684",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"27,72","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_070,4,106162523,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1146His/c.3437C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),17365,198,17643,"0,0112225812",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"27,68","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_071,4,106162523,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1146His/c.3437C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),16784,177,17037,"0,010389153",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"27,57","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106162523,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1146His/c.3437C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),18477,219,18780,"0,0116613419",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"27,53","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106162523,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1146His/c.3437C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),18352,231,18660,"0,0123794212",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"27,69","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_074,4,106162523,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1146His/c.3437C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),17475,220,17751,"0,012393668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"27,64","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_075,4,106162523,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1146His/c.3437C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),28444,359,28920,"0,0124135546",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"27,57","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_077,4,106162523,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1146His/c.3437C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),25094,291,25498,"0,0114126598",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"27,62","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_078,4,106162523,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1146His/c.3437C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),22967,250,23319,"0,0107208714",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"27,62","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_079,4,106162523,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1146His/c.3437C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),15239,171,15482,"0,0110450846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"27,63","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_080,4,106162523,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1146His/c.3437C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),22543,231,22865,"0,0101027772",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"27,61","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106162523,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1146His/c.3437C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),29972,381,30500,"0,0124918033",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"27,58","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_082,4,106162523,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1146His/c.3437C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),35168,402,35735,"0,0112494753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"27,52","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_083,4,106162523,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1146His/c.3437C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),30348,340,30820,"0,0110317975",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"27,8","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_084,4,106162523,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1146His/c.3437C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),34350,391,34879,"0,0112101838",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"27,66",15
"low bq, low freq, many artifacts, many samples",UPN2_085,4,106162523,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1146His/c.3437C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),29096,303,29532,"0,0102600569",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"27,66","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_086,4,106162523,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1146His/c.3437C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),20743,232,21059,"0,0110166675",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"27,76","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_087,4,106162523,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1146His/c.3437C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),35396,423,35991,"0,0117529382",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"27,59","14,6"
"low bq, low freq, many artifacts",UPN2_088,4,106162523,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1146His/c.3437C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),26695,303,27114,"0,0111750387",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"27,52","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_059,4,106162532,C,A,missense_variant(MODERATE|MISSENSE|aCc/aAc|p.Thr1149Asn/c.3446C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),27755,294,28197,"0,0104266411",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,34,Damaging,"29,42","15,17"
"low bq, low freq, many artifacts, many samples",UPN2_060,4,106162532,C,A,missense_variant(MODERATE|MISSENSE|aCc/aAc|p.Thr1149Asn/c.3446C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),26372,311,26828,"0,0115923662",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,34,Damaging,"29,39","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_062,4,106162532,C,A,missense_variant(MODERATE|MISSENSE|aCc/aAc|p.Thr1149Asn/c.3446C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),17552,196,17850,"0,0109803922",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,34,Damaging,"29,49","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_064,4,106162532,C,A,missense_variant(MODERATE|MISSENSE|aCc/aAc|p.Thr1149Asn/c.3446C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),19080,220,19404,"0,0113378685",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,34,Damaging,"29,43","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_066,4,106162532,C,A,missense_variant(MODERATE|MISSENSE|aCc/aAc|p.Thr1149Asn/c.3446C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),35665,399,36287,"0,0109956734",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,34,Damaging,"29,28","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_067,4,106162532,C,A,missense_variant(MODERATE|MISSENSE|aCc/aAc|p.Thr1149Asn/c.3446C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),39081,430,39751,"0,0108173379",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,34,Damaging,"29,26","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_068,4,106162532,C,A,missense_variant(MODERATE|MISSENSE|aCc/aAc|p.Thr1149Asn/c.3446C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),24853,257,25250,"0,0101782178",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,34,Damaging,"29,41","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_070,4,106162532,C,A,missense_variant(MODERATE|MISSENSE|aCc/aAc|p.Thr1149Asn/c.3446C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),17378,190,17669,"0,0107532967",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,34,Damaging,"29,33","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_071,4,106162532,C,A,missense_variant(MODERATE|MISSENSE|aCc/aAc|p.Thr1149Asn/c.3446C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),16790,187,17060,"0,010961313",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,34,Damaging,"29,35","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106162532,C,A,missense_variant(MODERATE|MISSENSE|aCc/aAc|p.Thr1149Asn/c.3446C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),18489,198,18807,"0,0105279949",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,34,Damaging,"29,28","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106162532,C,A,missense_variant(MODERATE|MISSENSE|aCc/aAc|p.Thr1149Asn/c.3446C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),18333,223,18686,"0,0119340683",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,34,Damaging,"29,41","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_074,4,106162532,C,A,missense_variant(MODERATE|MISSENSE|aCc/aAc|p.Thr1149Asn/c.3446C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),17466,200,17770,"0,011254924",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,34,Damaging,"29,44","15,49"
"low bq, low freq, many artifacts, many samples",UPN2_075,4,106162532,C,A,missense_variant(MODERATE|MISSENSE|aCc/aAc|p.Thr1149Asn/c.3446C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),28460,322,28974,"0,011113412",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,34,Damaging,"29,31","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_076,4,106162532,C,A,missense_variant(MODERATE|MISSENSE|aCc/aAc|p.Thr1149Asn/c.3446C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),25890,317,26374,"0,0120194131",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,34,Damaging,"29,47","16,8"
"low bq, low freq, many artifacts, many samples",UPN2_077,4,106162532,C,A,missense_variant(MODERATE|MISSENSE|aCc/aAc|p.Thr1149Asn/c.3446C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),25092,268,25520,"0,0105015674",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,34,Damaging,"29,39","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_078,4,106162532,C,A,missense_variant(MODERATE|MISSENSE|aCc/aAc|p.Thr1149Asn/c.3446C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),22968,267,23357,"0,0114312626",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,34,Damaging,"29,38","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_080,4,106162532,C,A,missense_variant(MODERATE|MISSENSE|aCc/aAc|p.Thr1149Asn/c.3446C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),22531,235,22896,"0,0102638015",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,34,Damaging,"29,39","15,3"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106162532,C,A,missense_variant(MODERATE|MISSENSE|aCc/aAc|p.Thr1149Asn/c.3446C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),30038,350,30554,"0,0114551286",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,34,Damaging,"29,33","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_082,4,106162532,C,A,missense_variant(MODERATE|MISSENSE|aCc/aAc|p.Thr1149Asn/c.3446C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),35199,384,35790,"0,010729254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,34,Damaging,"29,33","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_085,4,106162532,C,A,missense_variant(MODERATE|MISSENSE|aCc/aAc|p.Thr1149Asn/c.3446C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),29045,316,29570,"0,0106865066",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,34,Damaging,"29,35","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_086,4,106162532,C,A,missense_variant(MODERATE|MISSENSE|aCc/aAc|p.Thr1149Asn/c.3446C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),20713,260,21094,"0,0123257798",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,34,Damaging,"29,45","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_087,4,106162532,C,A,missense_variant(MODERATE|MISSENSE|aCc/aAc|p.Thr1149Asn/c.3446C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),35410,363,36023,"0,0100768953",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,34,Damaging,"29,34","14,82"
"low bq, low freq, many artifacts",UPN2_088,4,106162532,C,A,missense_variant(MODERATE|MISSENSE|aCc/aAc|p.Thr1149Asn/c.3446C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),26671,320,27147,"0,0117876745",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,34,Damaging,"29,41","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_058,4,106162534,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His1150Asn/c.3448C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),31763,327,32234,"0,0101445678",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,1,Damaging,"28,05","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_059,4,106162534,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His1150Asn/c.3448C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),27623,437,28189,"0,015502501",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,1,Damaging,"27,43","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_060,4,106162534,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His1150Asn/c.3448C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),26295,385,26825,"0,0143522833",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,1,Damaging,"27,45","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_061,4,106162534,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His1150Asn/c.3448C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),19448,277,19820,"0,013975782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,1,Damaging,"27,43","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_062,4,106162534,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His1150Asn/c.3448C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),17487,257,17839,"0,0144066371",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,1,Damaging,"27,52","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_063,4,106162534,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His1150Asn/c.3448C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),18102,295,18489,"0,015955433",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,1,Damaging,"27,47","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_064,4,106162534,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His1150Asn/c.3448C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),18975,302,19386,"0,0155782523",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,1,Damaging,"27,51","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_065,4,106162534,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His1150Asn/c.3448C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),22927,344,23385,"0,0147102844",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,1,Damaging,"27,38","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_066,4,106162534,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His1150Asn/c.3448C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),35543,548,36280,"0,0151047409",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,1,Damaging,"27,48","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_067,4,106162534,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His1150Asn/c.3448C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),38924,577,39737,"0,0145204721",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,1,Damaging,"27,3","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_068,4,106162534,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His1150Asn/c.3448C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),24770,360,25246,"0,0142596847",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,1,Damaging,"27,42","15,25"
"low bq, low freq, many artifacts, many samples",UPN2_069,4,106162534,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His1150Asn/c.3448C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),28786,438,29366,"0,0149152081",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,1,Damaging,"27,6","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_070,4,106162534,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His1150Asn/c.3448C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),17327,266,17662,"0,015060582",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,1,Damaging,"27,36","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_071,4,106162534,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His1150Asn/c.3448C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),16660,258,17046,"0,0151355157",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,1,Damaging,"27,37","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106162534,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His1150Asn/c.3448C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),18412,288,18802,"0,0153175194",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,1,Damaging,"27,37","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106162534,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His1150Asn/c.3448C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),18279,296,18678,"0,0158475211",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,1,Damaging,"27,4","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_074,4,106162534,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His1150Asn/c.3448C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),17402,246,17763,"0,013849012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,1,Damaging,"27,43","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_075,4,106162534,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His1150Asn/c.3448C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),28398,407,28967,"0,0140504712",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,1,Damaging,"27,33","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_076,4,106162534,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His1150Asn/c.3448C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),25902,332,26362,"0,0125938851",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,1,Damaging,"27,45","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_077,4,106162534,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His1150Asn/c.3448C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),25023,360,25506,"0,014114326",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,1,Damaging,"27,41","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_078,4,106162534,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His1150Asn/c.3448C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),22874,326,23345,"0,0139644463",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,1,Damaging,"27,43","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_079,4,106162534,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His1150Asn/c.3448C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),15216,200,15493,"0,0129090557",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,1,Damaging,"27,39","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_080,4,106162534,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His1150Asn/c.3448C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),22424,338,22885,"0,0147694997",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,1,Damaging,"27,4","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106162534,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His1150Asn/c.3448C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),29941,453,30539,"0,0148334916",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,1,Damaging,"27,39","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_082,4,106162534,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His1150Asn/c.3448C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),35066,510,35778,"0,0142545698",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,1,Damaging,"27,43","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_083,4,106162534,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His1150Asn/c.3448C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),30302,408,30844,"0,0132278563",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,1,Damaging,"27,61","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_084,4,106162534,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His1150Asn/c.3448C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),34197,515,34898,"0,0147572927",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,1,Damaging,"27,52","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_085,4,106162534,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His1150Asn/c.3448C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),28961,431,29549,"0,014585942",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,1,Damaging,"27,44","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_086,4,106162534,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His1150Asn/c.3448C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),20696,298,21089,"0,0141305894",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,1,Damaging,"27,56","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_087,4,106162534,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His1150Asn/c.3448C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),35297,519,36007,"0,014413864",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,1,Damaging,"27,4","14,47"
"low bq, low freq, many artifacts",UPN2_088,4,106162534,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His1150Asn/c.3448C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),26556,427,27133,"0,0157372941",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,1,Damaging,"27,41","14,77"
"low freq, many artifacts",UPN2_041,4,106162538,TA,T,frameshift_variant(HIGH||cta/|p.Gly1152fs/c.3453delA|2002|TET2|protein_coding|CODING|ENST00000380013|4|T),2509,39,2563,"0,0152165431",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,96",NA
"low bq, low freq, many artifacts, many samples",UPN2_063,4,106162541,G,T,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly1152Val/c.3455G>T|2002|TET2|protein_coding|CODING|ENST00000380013|4|T),18230,198,18493,"0,0107067539",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,15",Deleterious,0,Damaging,"29,05","15,71"
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106162541,G,T,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly1152Val/c.3455G>T|2002|TET2|protein_coding|CODING|ENST00000380013|4|T),18536,198,18793,"0,0105358378",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,15",Deleterious,0,Damaging,"29,01","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_059,4,106162544,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala1153Glu/c.3458C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),27737,324,28170,"0,0115015974",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,41",Deleterious,1,Damaging,"28,95","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_060,4,106162544,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala1153Glu/c.3458C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),26401,309,26821,"0,0115208232",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,41",Deleterious,1,Damaging,"28,92","16,21"
"low bq, low freq, many artifacts, many samples",UPN2_061,4,106162544,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala1153Glu/c.3458C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),19538,206,19819,"0,0103940663",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,41",Deleterious,1,Damaging,"28,85","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_062,4,106162544,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala1153Glu/c.3458C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),17574,189,17829,"0,0106007067",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,41",Deleterious,1,Damaging,"28,92","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_063,4,106162544,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala1153Glu/c.3458C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),18229,190,18490,"0,0102758248",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,41",Deleterious,1,Damaging,"28,88","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_064,4,106162544,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala1153Glu/c.3458C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),19111,211,19380,"0,0108875129",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,41",Deleterious,1,Damaging,"28,87","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_065,4,106162544,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala1153Glu/c.3458C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),23063,241,23389,"0,0103039891",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,41",Deleterious,1,Damaging,"28,77","15,73"
"low bq, low freq, many artifacts, many samples",UPN2_066,4,106162544,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala1153Glu/c.3458C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),35681,418,36254,"0,0115297622",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,41",Deleterious,1,Damaging,"28,86","15,17"
"low bq, low freq, many artifacts, many samples",UPN2_067,4,106162544,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala1153Glu/c.3458C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),39025,469,39702,"0,0118130069",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,41",Deleterious,1,Damaging,"28,73","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_069,4,106162544,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala1153Glu/c.3458C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),28931,303,29356,"0,0103215697",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,41",Deleterious,1,Damaging,"28,89","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_070,4,106162544,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala1153Glu/c.3458C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),17369,190,17636,"0,010773418",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,41",Deleterious,1,Damaging,"28,8","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106162544,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala1153Glu/c.3458C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),18485,222,18779,"0,0118217157",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,41",Deleterious,1,Damaging,"28,78","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106162544,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala1153Glu/c.3458C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),18407,199,18669,"0,0106593819",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,41",Deleterious,1,Damaging,"28,85","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_074,4,106162544,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala1153Glu/c.3458C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),17487,197,17760,"0,0110923423",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,41",Deleterious,1,Damaging,"28,86","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_075,4,106162544,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala1153Glu/c.3458C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),28447,361,28949,"0,0124702062",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,41",Deleterious,1,Damaging,"28,81","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_076,4,106162544,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala1153Glu/c.3458C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),25966,279,26349,"0,0105886371",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,41",Deleterious,1,Damaging,"28,9","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_077,4,106162544,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala1153Glu/c.3458C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),25108,278,25498,"0,0109028159",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,41",Deleterious,1,Damaging,"28,91","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_078,4,106162544,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala1153Glu/c.3458C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),22966,266,23336,"0,0113986973",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,41",Deleterious,1,Damaging,"28,9","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_079,4,106162544,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala1153Glu/c.3458C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),15260,178,15486,"0,0114942529",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,41",Deleterious,1,Damaging,"28,84","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_080,4,106162544,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala1153Glu/c.3458C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),22543,243,22865,"0,0106275968",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,41",Deleterious,1,Damaging,"28,9","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106162544,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala1153Glu/c.3458C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),30071,349,30536,"0,0114291328",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,41",Deleterious,1,Damaging,"28,79","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_082,4,106162544,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala1153Glu/c.3458C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),35215,397,35763,"0,0111008584",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,41",Deleterious,1,Damaging,"28,78","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_084,4,106162544,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala1153Glu/c.3458C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),34320,367,34870,"0,0105248064",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,41",Deleterious,1,Damaging,"28,87","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_085,4,106162544,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala1153Glu/c.3458C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),29087,329,29541,"0,0111370637",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,41",Deleterious,1,Damaging,"28,83","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_087,4,106162544,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala1153Glu/c.3458C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),35475,379,35998,"0,0105283627",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,41",Deleterious,1,Damaging,"28,8","14,76"
"low bq, low freq, many artifacts",UPN2_088,4,106162544,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala1153Glu/c.3458C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),26701,302,27115,"0,0111377466",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,41",Deleterious,1,Damaging,"28,82","15,19"
"low freq, many artifacts, low bqs",UPN2_041,4,106162544,C,G,missense_variant(MODERATE|MISSENSE|gCa/gGa|p.Ala1153Gly/c.3458C>G|2002|TET2|protein_coding|CODING|ENST00000380013|4|G),2500,38,2563,"0,0148263753",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,"0,003",Damaging,"29,39","27,63"
"low bq, low freq, many artifacts",UPN2_070,4,106162547,G,T,missense_variant(MODERATE|MISSENSE|gGt/gTt|p.Gly1154Val/c.3461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|4|T),17387,181,17630,"0,010266591",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,22",Deleterious,1,Damaging,"28,63","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_059,4,106162550,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1155His/c.3464C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),27737,310,28161,"0,0110081318",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,76",Deleterious,9,Damaging,"28,31","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_060,4,106162550,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1155His/c.3464C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),26423,284,26792,"0,0106001792",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,76",Deleterious,9,Damaging,"28,28","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_061,4,106162550,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1155His/c.3464C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),19535,199,19802,"0,01004949",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,76",Deleterious,9,Damaging,"28,21","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_063,4,106162550,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1155His/c.3464C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),18206,191,18480,"0,0103354978",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,76",Deleterious,9,Damaging,"28,33","15,52"
"low bq, low freq, many artifacts, many samples",UPN2_064,4,106162550,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1155His/c.3464C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),19112,198,19369,"0,0102225205",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,76",Deleterious,9,Damaging,"28,22",15
"low bq, low freq, many artifacts, many samples",UPN2_065,4,106162550,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1155His/c.3464C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),23049,252,23377,"0,0107798263",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,76",Deleterious,9,Damaging,"28,12","15,25"
"low bq, low freq, many artifacts, many samples",UPN2_067,4,106162550,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1155His/c.3464C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),39051,474,39681,"0,0119452635",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,76",Deleterious,9,Damaging,"28,14","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_068,4,106162550,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1155His/c.3464C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),24908,254,25220,"0,0100713719",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,76",Deleterious,9,Damaging,"28,3","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_070,4,106162550,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1155His/c.3464C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),17368,200,17626,"0,0113468739",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,76",Deleterious,9,Damaging,"28,26","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_071,4,106162550,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1155His/c.3464C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),16803,175,17041,"0,0102693504",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,76",Deleterious,9,Damaging,"28,13","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106162550,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1155His/c.3464C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),18471,217,18760,"0,0115671642",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,76",Deleterious,9,Damaging,"28,17","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106162550,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1155His/c.3464C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),18334,219,18656,"0,0117388508",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,76",Deleterious,9,Damaging,"28,3","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_075,4,106162550,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1155His/c.3464C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),28503,320,28931,"0,0110607998",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,76",Deleterious,9,Damaging,"28,16","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_076,4,106162550,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1155His/c.3464C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),25957,290,26328,"0,0110148891",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,76",Deleterious,9,Damaging,"28,3","15,42"
"low bq, low freq, many artifacts, many samples",UPN2_077,4,106162550,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1155His/c.3464C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),25117,292,25487,"0,0114568211",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,76",Deleterious,9,Damaging,"28,25","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_078,4,106162550,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1155His/c.3464C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),22992,262,23321,"0,0112345097",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,76",Deleterious,9,Damaging,"28,28","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_080,4,106162550,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1155His/c.3464C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),22510,258,22848,"0,0112920168",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,76",Deleterious,9,Damaging,"28,2","15,55"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106162550,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1155His/c.3464C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),30089,310,30515,"0,0101589382",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,76",Deleterious,9,Damaging,"28,11","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_082,4,106162550,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1155His/c.3464C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),35193,402,35737,"0,0112488457",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,76",Deleterious,9,Damaging,"28,16","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_084,4,106162550,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1155His/c.3464C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),34367,382,34845,"0,0109628354",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,76",Deleterious,9,Damaging,"28,3","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_085,4,106162550,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1155His/c.3464C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),29133,301,29521,"0,0101961316",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,76",Deleterious,9,Damaging,"28,18","15,48"
"low bq, low freq, many artifacts",UPN2_087,4,106162550,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro1155His/c.3464C>A|2002|TET2|protein_coding|CODING|ENST00000380013|4|A),35494,363,35984,"0,0100878168",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,76",Deleterious,9,Damaging,"28,2","15,37"
"inspected, many artifacts",UPN2_044,4,106162553,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn1156Ile/c.3467A>T|2002|TET2|protein_coding|CODING|ENST00000380013|4|T),3331,72,3412,"0,021101993",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,0,Damaging,"33,05",28
"low bq, low freq, many artifacts, many samples",UPN2_052,4,106162564,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile1160Phe/c.3478A>T|2002|TET2|protein_coding|CODING|ENST00000380013|4|T),12649,147,12834,"0,0114539504",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,72",Deleterious,1,Damaging,"33,26","18,52"
"low bq, low freq, many artifacts, many samples",UPN2_056,4,106162564,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile1160Phe/c.3478A>T|2002|TET2|protein_coding|CODING|ENST00000380013|4|T),5342,55,5408,"0,0101701183",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,72",Deleterious,1,Damaging,"33,12","19,58"
"low bq, low freq, many artifacts, many samples",UPN2_044,4,106162572,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu1162Asp/c.3486A>T|2002|TET2|protein_coding|CODING|ENST00000380013|4|T),1669,23,1699,"0,0135373749",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,13,Damaging,"33,78","17,65"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106162572,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu1162Asp/c.3486A>T|2002|TET2|protein_coding|CODING|ENST00000380013|4|T),12115,133,12297,"0,0108156461",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,13,Damaging,"33,69","18,87"
"low bq, low freq, many artifacts",UPN2_056,4,106162572,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu1162Asp/c.3486A>T|2002|TET2|protein_coding|CODING|ENST00000380013|4|T),5328,55,5409,"0,0101682381",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,13,Damaging,"33,53","17,05"
"low freq, many artifacts",UPN2_106,4,106162585,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg1167Trp/c.3499A>T|2002|TET2|protein_coding|CODING|ENST00000380013|4|T),7580,96,7703,"0,0124626769",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,4",Deleterious,0,Damaging,"34,6","32,84"
"inspected, many artifacts",UPN2_089,4,106163998,C,T,stop_gained(HIGH|NONSENSE|Cag/Tag|p.Gln1170*/c.3508C>T|2002|TET2|protein_coding|CODING|ENST00000380013|5|T),11632,263,11899,"0,0221026977",0,0,0,0,1,0,0,1,2,NO,NO,COSM43457,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,"2,24E-005",NO,NO,NA,NA,NA,NA,"35,59","35,56"
"low freq, many artifacts",UPN2_044,4,106164019,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile1177Phe/c.3529A>T|2002|TET2|protein_coding|CODING|ENST00000380013|5|T),3578,40,3622,"0,0110436223",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,"0,027",Damaging,"35,31","34,72"
inspected,UPN2_041,4,106164027,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg1179Ser/c.3537A>T|2002|TET2|protein_coding|CODING|ENST00000380013|5|T),821,26,849,"0,0306242638",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,68",Deleterious,"0,005",Damaging,"35,27","35,69"
"low bq, low freq, many artifacts, many samples",UPN2_059,4,106164029,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1180Gly/c.3539T>G|2002|TET2|protein_coding|CODING|ENST00000380013|5|G),54208,1075,55610,"0,0193310556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,64",Deleterious,0,Damaging,"29,25","17,03"
"low bq, low freq, many artifacts, many samples",UPN2_060,4,106164029,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1180Gly/c.3539T>G|2002|TET2|protein_coding|CODING|ENST00000380013|5|G),42844,909,44018,"0,0206506429",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,64",Deleterious,0,Damaging,"29,18","17,54"
"low bq, low freq, many artifacts, many samples",UPN2_061,4,106164029,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1180Gly/c.3539T>G|2002|TET2|protein_coding|CODING|ENST00000380013|5|G),33203,710,34061,"0,0208449546",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,64",Deleterious,0,Damaging,"29,19","16,78"
"low bq, many samples",UPN2_062,4,106164029,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1180Gly/c.3539T>G|2002|TET2|protein_coding|CODING|ENST00000380013|5|G),27460,634,28239,"0,0224512199",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,64",Deleterious,0,Damaging,"29,22","17,65"
"low bq, many samples",UPN2_063,4,106164029,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1180Gly/c.3539T>G|2002|TET2|protein_coding|CODING|ENST00000380013|5|G),32467,744,33348,"0,0223101835",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,64",Deleterious,0,Damaging,"29,21","17,01"
"low bq, low freq, many artifacts, many samples",UPN2_064,4,106164029,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1180Gly/c.3539T>G|2002|TET2|protein_coding|CODING|ENST00000380013|5|G),39079,800,40054,"0,0199730364",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,64",Deleterious,0,Damaging,"29,28","16,97"
"low bq, low freq, many artifacts, many samples",UPN2_065,4,106164029,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1180Gly/c.3539T>G|2002|TET2|protein_coding|CODING|ENST00000380013|5|G),42544,858,43597,"0,0196802532",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,64",Deleterious,0,Damaging,"29,27","17,56"
"low bq, low freq, many artifacts, many samples",UPN2_066,4,106164029,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1180Gly/c.3539T>G|2002|TET2|protein_coding|CODING|ENST00000380013|5|G),63880,1368,65596,"0,0208549302",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,64",Deleterious,0,Damaging,"29,16","17,04"
"low bq, low freq, many artifacts, many samples",UPN2_067,4,106164029,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1180Gly/c.3539T>G|2002|TET2|protein_coding|CODING|ENST00000380013|5|G),73196,1553,75143,"0,0206672611",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,64",Deleterious,0,Damaging,"29,3","17,32"
"low bq, low freq, many artifacts, many samples",UPN2_068,4,106164029,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1180Gly/c.3539T>G|2002|TET2|protein_coding|CODING|ENST00000380013|5|G),44210,900,45402,"0,0198229153",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,64",Deleterious,0,Damaging,"29,34","17,32"
"low bq, many samples",UPN2_069,4,106164029,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1180Gly/c.3539T>G|2002|TET2|protein_coding|CODING|ENST00000380013|5|G),49692,1124,51088,"0,0220012527",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,64",Deleterious,0,Damaging,"29,23","17,18"
"low bq, low freq, many artifacts, many samples",UPN2_070,4,106164029,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1180Gly/c.3539T>G|2002|TET2|protein_coding|CODING|ENST00000380013|5|G),30021,640,30838,"0,0207536157",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,64",Deleterious,0,Damaging,"29,29","17,35"
"low bq, low freq, many artifacts, many samples",UPN2_071,4,106164029,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1180Gly/c.3539T>G|2002|TET2|protein_coding|CODING|ENST00000380013|5|G),27776,598,28509,"0,0209758322",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,64",Deleterious,0,Damaging,"29,26","17,32"
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106164029,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1180Gly/c.3539T>G|2002|TET2|protein_coding|CODING|ENST00000380013|5|G),32451,641,33260,"0,0192723993",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,64",Deleterious,0,Damaging,"29,21","17,14"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106164029,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1180Gly/c.3539T>G|2002|TET2|protein_coding|CODING|ENST00000380013|5|G),30741,621,31532,"0,0196942788",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,64",Deleterious,0,Damaging,"29,28","17,34"
"low bq, many samples",UPN2_074,4,106164029,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1180Gly/c.3539T>G|2002|TET2|protein_coding|CODING|ENST00000380013|5|G),32391,753,33311,"0,0226051454",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,64",Deleterious,0,Damaging,"29,22","17,31"
"low bq, low freq, many artifacts, many samples",UPN2_075,4,106164029,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1180Gly/c.3539T>G|2002|TET2|protein_coding|CODING|ENST00000380013|5|G),46800,1003,48074,"0,0208636685",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,64",Deleterious,0,Damaging,"29,29","17,54"
"low bq, low freq, many artifacts, many samples",UPN2_076,4,106164029,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1180Gly/c.3539T>G|2002|TET2|protein_coding|CODING|ENST00000380013|5|G),40241,822,41260,"0,019922443",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,64",Deleterious,0,Damaging,"29,28","16,69"
"low bq, many samples",UPN2_077,4,106164029,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1180Gly/c.3539T>G|2002|TET2|protein_coding|CODING|ENST00000380013|5|G),42932,993,44167,"0,0224828492",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,64",Deleterious,0,Damaging,"29,13","17,29"
"low bq, low freq, many artifacts, many samples",UPN2_078,4,106164029,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1180Gly/c.3539T>G|2002|TET2|protein_coding|CODING|ENST00000380013|5|G),34781,757,35712,"0,0211973566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,64",Deleterious,0,Damaging,"29,23","16,85"
"low bq, low freq, many artifacts, many samples",UPN2_079,4,106164029,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1180Gly/c.3539T>G|2002|TET2|protein_coding|CODING|ENST00000380013|5|G),23073,466,23652,"0,0197023508",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,64",Deleterious,0,Damaging,"29,24",17
"low bq, low freq, many artifacts, many samples",UPN2_080,4,106164029,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1180Gly/c.3539T>G|2002|TET2|protein_coding|CODING|ENST00000380013|5|G),35387,676,36293,"0,0186261814",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,64",Deleterious,0,Damaging,"29,29","16,75"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106164029,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1180Gly/c.3539T>G|2002|TET2|protein_coding|CODING|ENST00000380013|5|G),49896,997,51203,"0,0194715153",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,64",Deleterious,0,Damaging,"29,34","17,08"
"low bq, low freq, many artifacts, many samples",UPN2_082,4,106164029,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1180Gly/c.3539T>G|2002|TET2|protein_coding|CODING|ENST00000380013|5|G),61376,1299,63009,"0,0206161025",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,64",Deleterious,0,Damaging,"29,26","17,02"
"low bq, low freq, many artifacts, many samples",UPN2_083,4,106164029,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1180Gly/c.3539T>G|2002|TET2|protein_coding|CODING|ENST00000380013|5|G),50621,1024,51917,"0,0197237899",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,64",Deleterious,0,Damaging,"29,3","17,05"
"low bq, low freq, many artifacts, many samples",UPN2_084,4,106164029,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1180Gly/c.3539T>G|2002|TET2|protein_coding|CODING|ENST00000380013|5|G),56964,1117,58368,"0,0191371985",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,64",Deleterious,0,Damaging,"29,38","17,34"
"low bq, low freq, many artifacts, many samples",UPN2_085,4,106164029,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1180Gly/c.3539T>G|2002|TET2|protein_coding|CODING|ENST00000380013|5|G),56287,1129,57673,"0,0195758847",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,64",Deleterious,0,Damaging,"29,28","17,33"
"low bq, low freq, many artifacts, many samples",UPN2_086,4,106164029,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1180Gly/c.3539T>G|2002|TET2|protein_coding|CODING|ENST00000380013|5|G),44619,892,45718,"0,0195109147",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,64",Deleterious,0,Damaging,"29,28","17,25"
"low bq, low freq, many artifacts, many samples",UPN2_087,4,106164029,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1180Gly/c.3539T>G|2002|TET2|protein_coding|CODING|ENST00000380013|5|G),57358,1174,58839,"0,0199527524",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,64",Deleterious,0,Damaging,"29,35","17,57"
"low bq, low freq, many artifacts",UPN2_088,4,106164029,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1180Gly/c.3539T>G|2002|TET2|protein_coding|CODING|ENST00000380013|5|G),47838,973,49071,"0,0198284119",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,64",Deleterious,0,Damaging,"29,25","17,34"
"inspected, many artifacts",UPN2_044,4,106164035,A,T,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr1182Phe/c.3545A>T|2002|TET2|protein_coding|CODING|ENST00000380013|5|T),6920,196,7143,"0,0274394512",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,83",Deleterious,"0,014",Damaging,"32,46","29,26"
"low bq, low freq, many artifacts",UPN2_058,4,106164037,A,T,missense_variant(MODERATE|MISSENSE|Act/Tct|p.Thr1183Ser/c.3547A>T|2002|TET2|protein_coding|CODING|ENST00000380013|5|T),44873,458,45431,"0,0100812221",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,11,Damaging,"32,51","23,13"
"low freq, many artifacts",UPN2_044,4,106164047,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu1186Gly/c.3557A>G|2002|TET2|protein_coding|CODING|ENST00000380013|5|G),7019,100,7155,"0,0139762404",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,71",Deleterious,0,Damaging,"33,16","33,89"
"low freq, many artifacts",UPN2_041,4,106164052,A,T,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys1188*/c.3562A>T|2002|TET2|protein_coding|CODING|ENST00000380013|5|T),1650,22,1684,"0,013064133",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,92","30,95"
"low bq, low freq, many artifacts, many samples",UPN2_044,4,106164053,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys1188Ile/c.3563A>T|2002|TET2|protein_coding|CODING|ENST00000380013|5|T),7055,80,7156,"0,0111794298",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,67",Deleterious,0,Damaging,"32,95","18,79"
"low bq, low freq, many artifacts, many samples",UPN2_050,4,106164053,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys1188Ile/c.3563A>T|2002|TET2|protein_coding|CODING|ENST00000380013|5|T),37474,386,38054,"0,0101434803",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,67",Deleterious,0,Damaging,"32,73","19,16"
"low bq, low freq, many artifacts, many samples",UPN2_056,4,106164053,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys1188Ile/c.3563A>T|2002|TET2|protein_coding|CODING|ENST00000380013|5|T),15400,171,15636,"0,0109363008",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,67",Deleterious,0,Damaging,"32,88","20,05"
"low freq, many artifacts",UPN2_041,4,106164058,T,C,missense_variant(MODERATE|MISSENSE|Tct/Cct|p.Ser1190Pro/c.3568T>C|2002|TET2|protein_coding|CODING|ENST00000380013|5|C),1658,20,1686,"0,0118623962",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,49",Deleterious,"0,002",Damaging,"33,67","35,6"
"low freq, many artifacts",UPN2_044,4,106164082,TG,T,splice_donor_variant+intron_variant(HIGH|||c.3594+1delG|2002|TET2|protein_coding|CODING|ENST00000380013|5|T|INFO_REALIGN_3_PRIME),7054,73,7172,"0,0101784718",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,97",NA
"low freq, many artifacts",UPN2_093,4,106164730,G,A,missense_variant(MODERATE|MISSENSE|Gtt/Att|p.Val1200Ile/c.3598G>A|2002|TET2|protein_coding|CODING|ENST00000380013|6|A),1357,21,1378,"0,0152394775",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,4",Neutral,"0,961",Tolerated,"35,56",36
"low freq, many artifacts",UPN2_092,4,106164730,G,C,missense_variant(MODERATE|MISSENSE|Gtt/Ctt|p.Val1200Leu/c.3598G>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),2648,30,2679,"0,0111982083",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,84",Neutral,"0,22",Tolerated,"35,57","35,6"
"low freq, many artifacts",UPN2_044,4,106164755,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1208Arg/c.3623A>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),1740,23,1767,"0,013016412",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,"0,002",Damaging,"34,08",36
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_060,4,106164788,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1219Pro/c.3656A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),2330,27,2377,"0,0113588557",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,6",Deleterious,0,Damaging,"25,86",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,4,106164788,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1219Pro/c.3656A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),2693,28,2747,"0,0101929378",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,6",Deleterious,0,Damaging,"25,87","15,68"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,4,106164788,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1219Pro/c.3656A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),2498,30,2539,"0,0118156755",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,6",Deleterious,0,Damaging,"25,81","15,4"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,4,106164788,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1219Pro/c.3656A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),3315,34,3364,"0,0101070155",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,6",Deleterious,0,Damaging,"25,73","15,56"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,4,106164788,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1219Pro/c.3656A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),3466,36,3519,"0,010230179",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,6",Deleterious,0,Damaging,"25,94","15,47"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_081,4,106164788,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1219Pro/c.3656A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),3739,43,3818,"0,0112624411",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,6",Deleterious,0,Damaging,"25,83","14,42"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,4,106164788,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1219Pro/c.3656A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),2932,41,2989,"0,0137169622",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,6",Deleterious,0,Damaging,"25,51","14,32"
"low bq, bad alignment, low freq, many artifacts",UPN2_084,4,106164788,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1219Pro/c.3656A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),3364,37,3437,"0,0107652022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,6",Deleterious,0,Damaging,"25,59","14,19"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_060,4,106164790,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1220Pro/c.3658A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),2331,32,2378,"0,0134566863",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,18",Neutral,27,Damaging,"24,74",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,4,106164790,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1220Pro/c.3658A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),2698,43,2752,"0,015625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,18",Neutral,27,Damaging,"25,26","15,74"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,4,106164790,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1220Pro/c.3658A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),3415,52,3495,"0,0148783977",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,18",Neutral,27,Damaging,"25,16","15,04"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,4,106164790,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1220Pro/c.3658A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),2499,31,2540,"0,0122047244",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,18",Neutral,27,Damaging,"24,79","15,94"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,4,106164790,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1220Pro/c.3658A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),1645,25,1677,"0,014907573",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,18",Neutral,27,Damaging,"24,93","14,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_068,4,106164790,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1220Pro/c.3658A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),1629,26,1669,"0,0155781905",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,18",Neutral,27,Damaging,"25,51","14,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_069,4,106164790,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1220Pro/c.3658A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),2344,43,2395,"0,017954071",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,18",Neutral,27,Damaging,"25,2","16,58"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_070,4,106164790,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1220Pro/c.3658A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),1668,24,1702,"0,0141010576",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,18",Neutral,27,Damaging,"25,01","15,12"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,4,106164790,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1220Pro/c.3658A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),3490,53,3562,"0,0148792813",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,18",Neutral,27,Damaging,"25,23","15,15"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,4,106164790,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1220Pro/c.3658A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),3287,62,3364,"0,01843044",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,18",Neutral,27,Damaging,"25,16","14,73"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,4,106164790,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1220Pro/c.3658A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),1915,30,1950,"0,0153846154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,18",Neutral,27,Damaging,"25,2","14,73"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_075,4,106164790,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1220Pro/c.3658A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),4042,61,4143,"0,0147236302",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,18",Neutral,27,Damaging,"25,32","14,89"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,4,106164790,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1220Pro/c.3658A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),2354,52,2420,"0,0214876033",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,18",Neutral,27,Damaging,"25,09","15,27"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,4,106164790,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1220Pro/c.3658A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),2022,37,2067,"0,0179003387",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,18",Neutral,27,Damaging,"25,71","15,03"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,4,106164790,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1220Pro/c.3658A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),3102,60,3192,"0,0187969925",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,18",Neutral,27,Damaging,"24,9","14,22"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_079,4,106164790,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1220Pro/c.3658A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),2003,35,2049,"0,0170815032",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,18",Neutral,27,Damaging,"25,22","17,09"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,4,106164790,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1220Pro/c.3658A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),3430,64,3523,"0,0181663355",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,18",Neutral,27,Damaging,"25,27","15,05"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_081,4,106164790,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1220Pro/c.3658A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),3730,60,3817,"0,0157191512",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,18",Neutral,27,Damaging,"25,64","14,33"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_082,4,106164790,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1220Pro/c.3658A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),1864,29,1905,"0,0152230971",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,18",Neutral,27,Damaging,"25,07",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,4,106164790,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1220Pro/c.3658A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),2931,45,2991,"0,0150451354",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,18",Neutral,27,Damaging,"24,89","15,09"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,4,106164790,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1220Pro/c.3658A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),3352,73,3438,"0,0212332752",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,18",Neutral,27,Damaging,"25,24","15,34"
"low bq, bad alignment, many samples",UPN2_086,4,106164790,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1220Pro/c.3658A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),937,23,971,"0,0236869207",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,18",Neutral,27,Damaging,"25,08","14,96"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_087,4,106164790,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1220Pro/c.3658A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),2807,36,2865,"0,012565445",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,18",Neutral,27,Damaging,"24,75","14,69"
"low bq, bad alignment, low freq, many artifacts",UPN2_088,4,106164790,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1220Pro/c.3658A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),1677,27,1717,"0,0157251019",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,18",Neutral,27,Damaging,"25,54","14,48"
"low freq, many artifacts",UPN2_090,4,106164790,A,T,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr1220Ser/c.3658A>T|2002|TET2|protein_coding|CODING|ENST00000380013|6|T),3840,46,3909,"0,0117677155",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,63",Neutral,"0,267",Tolerated,"28,93","34,78"
inspected,UPN2_044,4,106164791,C,T,missense_variant(MODERATE|MISSENSE|aCc/aTc|p.Thr1220Ile/c.3659C>T|2002|TET2|protein_coding|CODING|ENST00000380013|6|T),1601,48,1650,"0,0290909091",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,"3,91E-005",NO,NO,"-2,88",Deleterious,"0,016",Damaging,"34,56","34,62"
"low freq, many artifacts",UPN2_044,4,106164797,A,G,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu1222Gly/c.3665A>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),1619,28,1650,"0,016969697",0,0,0,0,1,0,0,1,2,NO,NO,COSM41651,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-4,63",Deleterious,"0,008",Damaging,"34,69","35,39"
"low freq, many artifacts",UPN2_048,4,106164808,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile1226Phe/c.3676A>T|2002|TET2|protein_coding|CODING|ENST00000380013|6|T),2261,29,2302,"0,0125977411",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,58",Deleterious,"0,001",Damaging,"35,05","34,83"
"low bq, low freq, many artifacts, many samples",UPN2_071,4,106164814,A,C,missense_variant(MODERATE|MISSENSE|Att/Ctt|p.Ile1228Leu/c.3682A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),3524,36,3577,"0,0100642997",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,4,Damaging,"30,36","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106164814,A,C,missense_variant(MODERATE|MISSENSE|Att/Ctt|p.Ile1228Leu/c.3682A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),3305,36,3365,"0,0106983655",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,4,Damaging,"30,36","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_083,4,106164814,A,C,missense_variant(MODERATE|MISSENSE|Att/Ctt|p.Ile1228Leu/c.3682A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),2963,31,3003,"0,0103230103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,4,Damaging,"30,2","14,42"
"low bq, low freq, many artifacts",UPN2_084,4,106164814,A,C,missense_variant(MODERATE|MISSENSE|Att/Ctt|p.Ile1228Leu/c.3682A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),3393,39,3441,"0,0113339146",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,4,Damaging,"30,02","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_076,4,106164815,T,G,missense_variant(MODERATE|MISSENSE|aTt/aGt|p.Ile1228Ser/c.3683T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),2442,31,2484,"0,0124798712",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,39",Deleterious,0,Damaging,"29,22","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_083,4,106164815,T,G,missense_variant(MODERATE|MISSENSE|aTt/aGt|p.Ile1228Ser/c.3683T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),3106,34,3147,"0,0108039403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,39",Deleterious,0,Damaging,"28,99",14
"low bq, low freq, many artifacts, many samples",UPN2_059,4,106164816,T,G,missense_variant(MODERATE|MISSENSE|atT/atG|p.Ile1228Met/c.3684T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),2010,30,2056,"0,0145914397",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,25,Damaging,"28,74","17,53"
"low bq, low freq, many artifacts, many samples",UPN2_060,4,106164816,T,G,missense_variant(MODERATE|MISSENSE|atT/atG|p.Ile1228Met/c.3684T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),4543,55,4628,"0,0118841832",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,25,Damaging,"28,7","16,18"
"low bq, low freq, many artifacts, many samples",UPN2_061,4,106164816,T,G,missense_variant(MODERATE|MISSENSE|atT/atG|p.Ile1228Met/c.3684T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),5312,72,5415,"0,0132963989",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,25,Damaging,"28,73","18,1"
"low bq, low freq, many artifacts, many samples",UPN2_062,4,106164816,T,G,missense_variant(MODERATE|MISSENSE|atT/atG|p.Ile1228Met/c.3684T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),6767,86,6890,"0,0124818578",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,25,Damaging,"28,49","16,47"
"low bq, low freq, many artifacts, many samples",UPN2_063,4,106164816,T,G,missense_variant(MODERATE|MISSENSE|atT/atG|p.Ile1228Met/c.3684T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),4880,60,4979,"0,0120506126",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,25,Damaging,"28,82","16,75"
"low bq, low freq, many artifacts, many samples",UPN2_064,4,106164816,T,G,missense_variant(MODERATE|MISSENSE|atT/atG|p.Ile1228Met/c.3684T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),3231,41,3286,"0,0124771759",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,25,Damaging,"28,7","15,51"
"low bq, low freq, many artifacts, many samples",UPN2_065,4,106164816,T,G,missense_variant(MODERATE|MISSENSE|atT/atG|p.Ile1228Met/c.3684T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),1691,27,1722,"0,0156794425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,25,Damaging,"29,02","16,96"
"low bq, low freq, many artifacts, many samples",UPN2_067,4,106164816,T,G,missense_variant(MODERATE|MISSENSE|atT/atG|p.Ile1228Met/c.3684T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),2647,30,2688,"0,0111607143",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,25,Damaging,"28,7","17,57"
"low bq, low freq, many artifacts, many samples",UPN2_068,4,106164816,T,G,missense_variant(MODERATE|MISSENSE|atT/atG|p.Ile1228Met/c.3684T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),3235,35,3287,"0,0106480073",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,25,Damaging,"28,73","17,46"
"low bq, low freq, many artifacts, many samples",UPN2_069,4,106164816,T,G,missense_variant(MODERATE|MISSENSE|atT/atG|p.Ile1228Met/c.3684T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),4639,56,4718,"0,0118694362",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,25,Damaging,"28,73","15,46"
"low bq, low freq, many artifacts, many samples",UPN2_070,4,106164816,T,G,missense_variant(MODERATE|MISSENSE|atT/atG|p.Ile1228Met/c.3684T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),3267,49,3338,"0,0146794488",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,25,Damaging,"28,65","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_071,4,106164816,T,G,missense_variant(MODERATE|MISSENSE|atT/atG|p.Ile1228Met/c.3684T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),6898,79,7010,"0,0112696148",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,25,Damaging,"28,83","16,3"
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106164816,T,G,missense_variant(MODERATE|MISSENSE|atT/atG|p.Ile1228Met/c.3684T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),6478,75,6589,"0,0113826074",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,25,Damaging,"28,79","17,15"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106164816,T,G,missense_variant(MODERATE|MISSENSE|atT/atG|p.Ile1228Met/c.3684T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),3774,50,3839,"0,0130242251",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,25,Damaging,"28,75","15,94"
"low bq, low freq, many artifacts, many samples",UPN2_075,4,106164816,T,G,missense_variant(MODERATE|MISSENSE|atT/atG|p.Ile1228Met/c.3684T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),8000,105,8154,"0,0128771155",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,25,Damaging,"28,89","16,72"
"low bq, low freq, many artifacts, many samples",UPN2_076,4,106164816,T,G,missense_variant(MODERATE|MISSENSE|atT/atG|p.Ile1228Met/c.3684T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),4671,65,4761,"0,013652594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,25,Damaging,"28,51","16,88"
"low bq, low freq, many artifacts, many samples",UPN2_077,4,106164816,T,G,missense_variant(MODERATE|MISSENSE|atT/atG|p.Ile1228Met/c.3684T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),3995,67,4083,"0,0164095028",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,25,Damaging,"28,78","17,42"
"low bq, low freq, many artifacts, many samples",UPN2_078,4,106164816,T,G,missense_variant(MODERATE|MISSENSE|atT/atG|p.Ile1228Met/c.3684T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),6160,82,6285,"0,0130469372",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,25,Damaging,"28,55","17,23"
"low bq, low freq, many artifacts, many samples",UPN2_079,4,106164816,T,G,missense_variant(MODERATE|MISSENSE|atT/atG|p.Ile1228Met/c.3684T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),3934,51,4008,"0,0127245509",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,25,Damaging,"28,88","15,92"
"low bq, low freq, many artifacts, many samples",UPN2_080,4,106164816,T,G,missense_variant(MODERATE|MISSENSE|atT/atG|p.Ile1228Met/c.3684T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),6821,81,6957,"0,0116429495",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,25,Damaging,"28,74","16,84"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106164816,T,G,missense_variant(MODERATE|MISSENSE|atT/atG|p.Ile1228Met/c.3684T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),7350,78,7467,"0,0104459622",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,25,Damaging,"28,99","16,65"
"low bq, low freq, many artifacts, many samples",UPN2_082,4,106164816,T,G,missense_variant(MODERATE|MISSENSE|atT/atG|p.Ile1228Met/c.3684T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),3680,39,3742,"0,0104222341",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,25,Damaging,"28,9","16,56"
"low bq, low freq, many artifacts, many samples",UPN2_083,4,106164816,T,G,missense_variant(MODERATE|MISSENSE|atT/atG|p.Ile1228Met/c.3684T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),5732,92,5869,"0,0156755836",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,25,Damaging,"28,61","17,11"
"low bq, low freq, many artifacts, many samples",UPN2_084,4,106164816,T,G,missense_variant(MODERATE|MISSENSE|atT/atG|p.Ile1228Met/c.3684T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),6635,83,6760,"0,0122781065",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,25,Damaging,"28,6","17,17"
"low bq, low freq, many artifacts, many samples",UPN2_085,4,106164816,T,G,missense_variant(MODERATE|MISSENSE|atT/atG|p.Ile1228Met/c.3684T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),2982,41,3042,"0,013477975",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,25,Damaging,"28,83","16,66"
"low bq, low freq, many artifacts, many samples",UPN2_086,4,106164816,T,G,missense_variant(MODERATE|MISSENSE|atT/atG|p.Ile1228Met/c.3684T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),1870,24,1907,"0,0125852124",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,25,Damaging,"28,88","17,21"
"low bq, low freq, many artifacts",UPN2_088,4,106164816,T,G,missense_variant(MODERATE|MISSENSE|atT/atG|p.Ile1228Met/c.3684T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),3296,38,3358,"0,0113162597",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,25,Damaging,"28,82","17,39"
"low bq, low freq, many artifacts, many samples",UPN2_061,4,106164820,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1230Leu/c.3688A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),5321,60,5428,"0,0110537951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,91",Neutral,17,Damaging,"27,41","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_062,4,106164820,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1230Leu/c.3688A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),6778,72,6914,"0,0104136535",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,91",Neutral,17,Damaging,"27,26","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_064,4,106164820,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1230Leu/c.3688A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),3265,38,3321,"0,0114423366",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,91",Neutral,17,Damaging,"27,33",14
"low bq, low freq, many artifacts, many samples",UPN2_065,4,106164820,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1230Leu/c.3688A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),1725,20,1762,"0,0113507378",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,91",Neutral,17,Damaging,"27,65","17,75"
"low bq, low freq, many artifacts, many samples",UPN2_068,4,106164820,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1230Leu/c.3688A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),3235,37,3296,"0,0112257282",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,91",Neutral,17,Damaging,"27,36","15,41"
"low bq, low freq, many artifacts, many samples",UPN2_070,4,106164820,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1230Leu/c.3688A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),3277,37,3354,"0,0110316041",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,91",Neutral,17,Damaging,"27,08","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_077,4,106164820,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1230Leu/c.3688A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),4022,42,4090,"0,0102689487",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,91",Neutral,17,Damaging,"27,52","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_082,4,106164820,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1230Leu/c.3688A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),3690,40,3757,"0,0106467927",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,91",Neutral,17,Damaging,"27,37","14,32"
"low bq, low freq, many artifacts",UPN2_087,4,106164820,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1230Leu/c.3688A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),5560,62,5658,"0,0109579357",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,91",Neutral,17,Damaging,"27,49","14,11"
"low bq, low freq, many artifacts, many samples",UPN2_059,4,106164827,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1232Gly/c.3695T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),2034,21,2065,"0,0101694915",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,87",Deleterious,0,Damaging,"29,39","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_060,4,106164827,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1232Gly/c.3695T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),4597,68,4698,"0,0144742444",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,87",Deleterious,0,Damaging,"29,14","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_061,4,106164827,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1232Gly/c.3695T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),5336,71,5436,"0,0130610743",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,87",Deleterious,0,Damaging,"28,97","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_062,4,106164827,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1232Gly/c.3695T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),6783,96,6923,"0,0138668207",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,87",Deleterious,0,Damaging,"28,72","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_063,4,106164827,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1232Gly/c.3695T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),4917,80,5021,"0,0159330811",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,87",Deleterious,0,Damaging,"29,19","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_064,4,106164827,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1232Gly/c.3695T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),3263,40,3326,"0,0120264582",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,87",Deleterious,0,Damaging,"28,97","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_065,4,106164827,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1232Gly/c.3695T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),1729,25,1764,"0,0141723356",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,87",Deleterious,0,Damaging,"28,99",14
"low bq, low freq, many artifacts, many samples",UPN2_066,4,106164827,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1232Gly/c.3695T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),1825,31,1867,"0,0166041778",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,87",Deleterious,0,Damaging,"29,02","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_067,4,106164827,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1232Gly/c.3695T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),2667,40,2718,"0,0147167035",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,87",Deleterious,0,Damaging,"29,17","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_068,4,106164827,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1232Gly/c.3695T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),3234,46,3303,"0,0139267333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,87",Deleterious,0,Damaging,"28,97","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_069,4,106164827,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1232Gly/c.3695T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),4653,61,4742,"0,0128637706",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,87",Deleterious,0,Damaging,"29,1","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_070,4,106164827,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1232Gly/c.3695T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),3292,47,3359,"0,0139922596",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,87",Deleterious,0,Damaging,"28,98","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_071,4,106164827,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1232Gly/c.3695T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),6931,90,7050,"0,0127659574",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,87",Deleterious,0,Damaging,"29,09","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106164827,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1232Gly/c.3695T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),6494,103,6642,"0,0155073773",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,87",Deleterious,0,Damaging,"29,21","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106164827,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1232Gly/c.3695T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),3786,61,3865,"0,0157826649",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,87",Deleterious,0,Damaging,"28,9","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_074,4,106164827,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1232Gly/c.3695T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),2156,27,2197,"0,0122894857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,87",Deleterious,0,Damaging,"28,96",14
"low bq, low freq, many artifacts, many samples",UPN2_075,4,106164827,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1232Gly/c.3695T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),8032,135,8208,"0,0164473684",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,87",Deleterious,0,Damaging,"29,19","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_076,4,106164827,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1232Gly/c.3695T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),4687,78,4799,"0,0162533861",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,87",Deleterious,0,Damaging,"28,89","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_077,4,106164827,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1232Gly/c.3695T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),4032,51,4097,"0,0124481328",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,87",Deleterious,0,Damaging,"28,8","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_078,4,106164827,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1232Gly/c.3695T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),6188,102,6322,"0,0161341348",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,87",Deleterious,0,Damaging,"28,83","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_079,4,106164827,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1232Gly/c.3695T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),3985,52,4052,"0,0128331688",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,87",Deleterious,0,Damaging,"28,99","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_080,4,106164827,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1232Gly/c.3695T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),6849,86,6975,"0,0123297491",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,87",Deleterious,0,Damaging,"29,07","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106164827,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1232Gly/c.3695T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),7374,120,7538,"0,015919342",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,87",Deleterious,0,Damaging,"29,19","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_082,4,106164827,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1232Gly/c.3695T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),3695,49,3762,"0,0130249867",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,87",Deleterious,0,Damaging,"29,17","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_083,4,106164827,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1232Gly/c.3695T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),5776,87,5923,"0,0146885024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,87",Deleterious,0,Damaging,"28,85","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_084,4,106164827,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1232Gly/c.3695T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),6674,104,6811,"0,0152694171",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,87",Deleterious,0,Damaging,"28,92","14,12"
"low bq, low freq, many artifacts, many samples",UPN2_085,4,106164827,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1232Gly/c.3695T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),2993,41,3056,"0,0134162304",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,87",Deleterious,0,Damaging,"29,35","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_086,4,106164827,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1232Gly/c.3695T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),1871,39,1926,"0,0202492212",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,87",Deleterious,0,Damaging,"28,95","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_087,4,106164827,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1232Gly/c.3695T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),5562,65,5664,"0,0114759887",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,87",Deleterious,0,Damaging,"29,09","14,89"
"low bq, low freq, many artifacts",UPN2_088,4,106164827,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1232Gly/c.3695T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),3327,45,3384,"0,0132978723",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,87",Deleterious,0,Damaging,"29,13","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_059,4,106164829,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp1233Gly/c.3697T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),2024,29,2065,"0,0140435835",0,0,0,0,1,0,0,0,1,NO,NO,COSM211621,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-12,01",Deleterious,24,Damaging,"28,97","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_060,4,106164829,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp1233Gly/c.3697T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),4602,74,4699,"0,0157480315",0,0,0,0,1,0,0,0,1,NO,NO,COSM211621,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-12,01",Deleterious,24,Damaging,"28,81","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_093,4,106164829,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp1233Gly/c.3697T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),2692,29,2734,"0,010607169",0,0,0,0,1,0,0,0,1,NO,NO,COSM211621,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-12,01",Deleterious,24,Damaging,"30,68","21,03"
"low bq, low freq, many artifacts, many samples",UPN2_061,4,106164829,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp1233Gly/c.3697T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),5282,118,5437,"0,0217031451",0,0,0,0,1,0,0,0,1,NO,NO,COSM211621,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-12,01",Deleterious,24,Damaging,"29,06","16,49"
"low bq, low freq, many artifacts, many samples",UPN2_062,4,106164829,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp1233Gly/c.3697T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),6755,121,6926,"0,0174704014",0,0,0,0,1,0,0,0,1,NO,NO,COSM211621,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-12,01",Deleterious,24,Damaging,"28,88","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_063,4,106164829,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp1233Gly/c.3697T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),4889,102,5023,"0,0203065897",0,0,0,0,1,0,0,0,1,NO,NO,COSM211621,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-12,01",Deleterious,24,Damaging,"29,13","17,77"
"low bq, low freq, many artifacts, many samples",UPN2_064,4,106164829,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp1233Gly/c.3697T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),3259,52,3327,"0,0156296964",0,0,0,0,1,0,0,0,1,NO,NO,COSM211621,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-12,01",Deleterious,24,Damaging,"28,95","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_065,4,106164829,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp1233Gly/c.3697T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),1715,35,1764,"0,0198412698",0,0,0,0,1,0,0,0,1,NO,NO,COSM211621,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-12,01",Deleterious,24,Damaging,"29,37","14,2"
"low bq, low freq, many artifacts, many samples",UPN2_066,4,106164829,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp1233Gly/c.3697T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),1827,30,1868,"0,0160599572",0,0,0,0,1,0,0,0,1,NO,NO,COSM211621,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-12,01",Deleterious,24,Damaging,"29,28","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_067,4,106164829,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp1233Gly/c.3697T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),2647,50,2718,"0,0183958793",0,0,0,0,1,0,0,0,1,NO,NO,COSM211621,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-12,01",Deleterious,24,Damaging,"28,95","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_068,4,106164829,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp1233Gly/c.3697T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),3237,52,3303,"0,0157432637",0,0,0,0,1,0,0,0,1,NO,NO,COSM211621,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-12,01",Deleterious,24,Damaging,"28,86","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_069,4,106164829,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp1233Gly/c.3697T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),4642,82,4743,"0,0172886359",0,0,0,0,1,0,0,0,1,NO,NO,COSM211621,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-12,01",Deleterious,24,Damaging,"28,86","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_070,4,106164829,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp1233Gly/c.3697T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),3276,63,3359,"0,018755582",0,0,0,0,1,0,0,0,1,NO,NO,COSM211621,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-12,01",Deleterious,24,Damaging,"28,91","16,1"
"low bq, low freq, many artifacts, many samples",UPN2_071,4,106164829,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp1233Gly/c.3697T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),6900,117,7052,"0,016591038",0,0,0,0,1,0,0,0,1,NO,NO,COSM211621,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-12,01",Deleterious,24,Damaging,"29,36","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106164829,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp1233Gly/c.3697T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),6512,93,6642,"0,0140018067",0,0,0,0,1,0,0,0,1,NO,NO,COSM211621,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-12,01",Deleterious,24,Damaging,"29,07","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106164829,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp1233Gly/c.3697T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),3777,66,3866,"0,0170719089",0,0,0,0,1,0,0,0,1,NO,NO,COSM211621,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-12,01",Deleterious,24,Damaging,"28,89","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_074,4,106164829,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp1233Gly/c.3697T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),2146,37,2197,"0,016841147",0,0,0,0,1,0,0,0,1,NO,NO,COSM211621,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-12,01",Deleterious,24,Damaging,"28,77","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_075,4,106164829,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp1233Gly/c.3697T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),8018,141,8209,"0,0171762699",0,0,0,0,1,0,0,0,1,NO,NO,COSM211621,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-12,01",Deleterious,24,Damaging,"29,08","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_076,4,106164829,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp1233Gly/c.3697T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),4703,67,4799,"0,0139612419",0,0,0,0,1,0,0,0,1,NO,NO,COSM211621,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-12,01",Deleterious,24,Damaging,"28,76","14,19"
"low bq, low freq, many artifacts, many samples",UPN2_077,4,106164829,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp1233Gly/c.3697T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),4006,65,4098,"0,0158613958",0,0,0,0,1,0,0,0,1,NO,NO,COSM211621,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-12,01",Deleterious,24,Damaging,"28,83","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_078,4,106164829,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp1233Gly/c.3697T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),6164,115,6323,"0,0181875692",0,0,0,0,1,0,0,0,1,NO,NO,COSM211621,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-12,01",Deleterious,24,Damaging,"28,66","15,77"
"low bq, low freq, many artifacts, many samples",UPN2_079,4,106164829,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp1233Gly/c.3697T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),3963,66,4052,"0,0162882527",0,0,0,0,1,0,0,0,1,NO,NO,COSM211621,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-12,01",Deleterious,24,Damaging,"29,05","15,91"
"low bq, low freq, many artifacts, many samples",UPN2_080,4,106164829,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp1233Gly/c.3697T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),6822,108,6975,"0,015483871",0,0,0,0,1,0,0,0,1,NO,NO,COSM211621,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-12,01",Deleterious,24,Damaging,"29,06","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106164829,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp1233Gly/c.3697T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),7351,129,7540,"0,0171087533",0,0,0,0,1,0,0,0,1,NO,NO,COSM211621,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-12,01",Deleterious,24,Damaging,"29,06","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_082,4,106164829,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp1233Gly/c.3697T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),3683,60,3763,"0,015944725",0,0,0,0,1,0,0,0,1,NO,NO,COSM211621,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-12,01",Deleterious,24,Damaging,"29,18","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_083,4,106164829,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp1233Gly/c.3697T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),5792,104,5927,"0,0175468196",0,0,0,0,1,0,0,0,1,NO,NO,COSM211621,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-12,01",Deleterious,24,Damaging,"28,75","15,39"
"low bq, low freq, many artifacts, many samples",UPN2_084,4,106164829,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp1233Gly/c.3697T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),6664,128,6812,"0,0187903699",0,0,0,0,1,0,0,0,1,NO,NO,COSM211621,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-12,01",Deleterious,24,Damaging,"29,07","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_085,4,106164829,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp1233Gly/c.3697T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),2984,62,3056,"0,0202879581",0,0,0,0,1,0,0,0,1,NO,NO,COSM211621,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-12,01",Deleterious,24,Damaging,"28,99","16,34"
"low bq, low freq, many artifacts, many samples",UPN2_086,4,106164829,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp1233Gly/c.3697T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),1880,36,1928,"0,0186721992",0,0,0,0,1,0,0,0,1,NO,NO,COSM211621,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-12,01",Deleterious,24,Damaging,"28,68",14
"low bq, low freq, many artifacts, many samples",UPN2_087,4,106164829,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp1233Gly/c.3697T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),5543,89,5664,"0,0157132768",0,0,0,0,1,0,0,0,1,NO,NO,COSM211621,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-12,01",Deleterious,24,Damaging,"28,8","15,73"
"low bq, low freq, many artifacts",UPN2_088,4,106164829,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp1233Gly/c.3697T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),3298,58,3385,"0,0171344165",0,0,0,0,1,0,0,0,1,NO,NO,COSM211621,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-12,01",Deleterious,24,Damaging,"29,03","15,57"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_059,4,106164838,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1236Leu/c.3706A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),2014,27,2067,"0,0130624093",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,32,Damaging,"25,32","14,67"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_060,4,106164838,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1236Leu/c.3706A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),4578,78,4701,"0,0165922144",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,32,Damaging,"25,27","14,58"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,4,106164838,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1236Leu/c.3706A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),5279,100,5442,"0,0183755972",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,32,Damaging,"25,36","14,2"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,4,106164838,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1236Leu/c.3706A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),6720,132,6929,"0,019050368",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,32,Damaging,"25,08","14,26"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,4,106164838,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1236Leu/c.3706A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),4916,83,5027,"0,0165108415",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,32,Damaging,"25,33","14,47"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,4,106164838,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1236Leu/c.3706A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),3223,68,3330,"0,0204204204",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,32,Damaging,"25,48","15,1"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_065,4,106164838,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1236Leu/c.3706A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),1721,36,1765,"0,0203966006",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,32,Damaging,"25,76","14,36"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_066,4,106164838,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1236Leu/c.3706A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),1816,27,1864,"0,0144849785",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,32,Damaging,"25,36","14,74"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_067,4,106164838,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1236Leu/c.3706A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),2648,52,2720,"0,0191176471",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,32,Damaging,"25,37","14,25"
"low bq, bad alignment, many samples",UPN2_068,4,106164838,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1236Leu/c.3706A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),3198,74,3303,"0,0224038753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,32,Damaging,"25,04",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_069,4,106164838,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1236Leu/c.3706A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),4622,78,4744,"0,0164418212",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,32,Damaging,"25,21","14,33"
"low bq, bad alignment, many samples",UPN2_070,4,106164838,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1236Leu/c.3706A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),3247,74,3355,"0,0220566319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,32,Damaging,"25,21","14,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,4,106164838,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1236Leu/c.3706A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),6872,122,7057,"0,0172877993",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,32,Damaging,"25,67","15,17"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,4,106164838,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1236Leu/c.3706A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),6453,109,6645,"0,0164033108",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,32,Damaging,"25,33","14,3"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,4,106164838,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1236Leu/c.3706A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),3763,80,3869,"0,0206771776",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,32,Damaging,"25,55","14,25"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,4,106164838,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1236Leu/c.3706A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),2132,35,2195,"0,0159453303",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,32,Damaging,"25,24",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_075,4,106164838,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1236Leu/c.3706A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),8004,138,8206,"0,0168169632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,32,Damaging,"25,45","14,37"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,4,106164838,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1236Leu/c.3706A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),4676,83,4802,"0,0172844648",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,32,Damaging,"25,28","14,4"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,4,106164838,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1236Leu/c.3706A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),3986,80,4099,"0,0195169554",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,32,Damaging,"25,58","14,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,4,106164838,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1236Leu/c.3706A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),6169,106,6328,"0,0167509482",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,32,Damaging,"25,25","14,42"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_079,4,106164838,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1236Leu/c.3706A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),3943,71,4054,"0,0175135668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,32,Damaging,"25,74","15,03"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,4,106164838,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1236Leu/c.3706A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),6794,118,6977,"0,0169127132",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,32,Damaging,"25,41","14,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_081,4,106164838,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1236Leu/c.3706A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),7341,139,7543,"0,0184276813",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,32,Damaging,"25,67","15,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_082,4,106164838,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1236Leu/c.3706A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),3682,48,3763,"0,01275578",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,32,Damaging,"25,34","15,56"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,4,106164838,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1236Leu/c.3706A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),5714,111,5924,"0,0187373396",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,32,Damaging,"25,21","14,58"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,4,106164838,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1236Leu/c.3706A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),6627,122,6813,"0,0179069426",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,32,Damaging,"25,34","14,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_085,4,106164838,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1236Leu/c.3706A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),2978,58,3058,"0,0189666449",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,32,Damaging,"25,47","14,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,4,106164838,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1236Leu/c.3706A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),1879,31,1929,"0,0160705029",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,32,Damaging,"25,17","15,26"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_087,4,106164838,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1236Leu/c.3706A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),5511,99,5662,"0,0174849876",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,32,Damaging,"25,41","14,32"
"low bq, bad alignment, low freq, many artifacts",UPN2_088,4,106164838,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1236Leu/c.3706A>C|2002|TET2|protein_coding|CODING|ENST00000380013|6|C),3306,45,3389,"0,0132782532",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,32,Damaging,"25,56","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_068,4,106164839,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile1236Ser/c.3707T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),3257,34,3304,"0,0102905569",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,53",Deleterious,0,Damaging,"29,06","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106164839,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile1236Ser/c.3707T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),3813,41,3869,"0,0105970535",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,53",Deleterious,0,Damaging,"28,9","15,51"
"low bq, low freq, many artifacts, many samples",UPN2_084,4,106164839,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile1236Ser/c.3707T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),6723,71,6813,"0,0104212535",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,53",Deleterious,0,Damaging,"28,91","14,41"
"low bq, low freq, many artifacts",UPN2_086,4,106164839,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile1236Ser/c.3707T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),1902,24,1929,"0,0124416796",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,53",Deleterious,0,Damaging,"28,85",14
"low freq, many artifacts",UPN2_065,4,106164841,C,A,missense_variant(MODERATE|MISSENSE|Ccg/Acg|p.Pro1237Thr/c.3709C>A|2002|TET2|protein_coding|CODING|ENST00000380013|6|A),1731,23,1765,"0,0130311615",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,52",Deleterious,"0,018",Damaging,"30,56","31,17"
"low bq, low freq, many artifacts, many samples",UPN2_059,4,106164847,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser1239Ala/c.3715T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),2035,28,2067,"0,0135462022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,32","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_060,4,106164847,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser1239Ala/c.3715T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),4617,58,4692,"0,0123614663",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,23","15,64"
"low bq, low freq, many artifacts, many samples",UPN2_061,4,106164847,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser1239Ala/c.3715T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),5345,60,5431,"0,0110476892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"27,98","15,55"
"low bq, low freq, many artifacts, many samples",UPN2_063,4,106164847,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser1239Ala/c.3715T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),4944,64,5021,"0,0127464648",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,44","14,2"
"low bq, low freq, many artifacts, many samples",UPN2_066,4,106164847,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser1239Ala/c.3715T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),1828,22,1860,"0,011827957",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,64",14
"low bq, low freq, many artifacts, many samples",UPN2_067,4,106164847,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser1239Ala/c.3715T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),2673,29,2712,"0,0106932153",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,29","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_068,4,106164847,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser1239Ala/c.3715T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),3243,34,3292,"0,010328068",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,05","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106164847,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser1239Ala/c.3715T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),6541,75,6631,"0,0113105112",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,49","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106164847,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser1239Ala/c.3715T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),3809,43,3867,"0,0111197311",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,13",14
"low bq, low freq, many artifacts, many samples",UPN2_074,4,106164847,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser1239Ala/c.3715T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),2160,24,2190,"0,0109589041",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,38","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_075,4,106164847,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser1239Ala/c.3715T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),8072,86,8193,"0,0104967655",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,52","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_076,4,106164847,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser1239Ala/c.3715T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),4708,55,4786,"0,0114918512",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"27,92","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_077,4,106164847,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser1239Ala/c.3715T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),4022,47,4090,"0,0114914425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,38","14,15"
"low bq, low freq, many artifacts, many samples",UPN2_078,4,106164847,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser1239Ala/c.3715T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),6194,71,6311,"0,0112501981",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,05","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_080,4,106164847,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser1239Ala/c.3715T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),6859,72,6963,"0,0103403705",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,43","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106164847,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser1239Ala/c.3715T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),7418,85,7535,"0,0112806901",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,52","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_082,4,106164847,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser1239Ala/c.3715T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),3687,44,3754,"0,0117208311",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,61","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_083,4,106164847,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser1239Ala/c.3715T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),5820,81,5918,"0,0136870564",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,14","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_084,4,106164847,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser1239Ala/c.3715T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),6692,78,6801,"0,0114689016",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,13","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_085,4,106164847,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser1239Ala/c.3715T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),3009,40,3056,"0,0130890052",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,66","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_086,4,106164847,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser1239Ala/c.3715T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),1892,21,1926,"0,0109034268",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,23","14,95"
"low bq, low freq, many artifacts",UPN2_087,4,106164847,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser1239Ala/c.3715T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),5570,65,5652,"0,0115003539",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,54",14
"low freq, many artifacts",UPN2_044,4,106164851,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu1240Gln/c.3719T>A|2002|TET2|protein_coding|CODING|ENST00000380013|6|A),3126,35,3223,"0,0108594477",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,"0,006",Damaging,"28,96","26,31"
"low bq, low freq, many artifacts, many samples",UPN2_001,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),9465,121,9630,"0,0125649013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"29,56","15,4"
"low bq, many samples",UPN2_014,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),10210,236,10489,"0,0224997617",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,08","15,06"
"low bq, many samples",UPN2_015,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),15114,402,15602,"0,0257659274",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"27,96","15,04"
"low bq, many samples",UPN2_016,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),7278,177,7495,"0,0236157438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,14","15,05"
"low bq, many samples",UPN2_017,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),4576,137,4739,"0,0289090525",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,13","15,17"
"low bq, many samples",UPN2_018,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),7428,208,7685,"0,0270657124",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,13","15,34"
"low bq, many samples",UPN2_019,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),8984,226,9256,"0,0244165946",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"27,95","15,07"
"low bq, many samples",UPN2_020,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),6692,184,6888,"0,0267131243",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,08","15,2"
"low bq, many samples",UPN2_021,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),8048,211,8307,"0,0254002648",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,08","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_002,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),11244,150,11436,"0,0131164743",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"29,42","14,86"
"low bq, many samples",UPN2_022,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),11180,332,11559,"0,0287222078",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,17","15,05"
"low bq, many samples",UPN2_023,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),11985,318,12388,"0,0256700032",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,02","14,98"
"low bq, many samples",UPN2_024,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),5433,131,5602,"0,0233845055",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,27","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_025,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),13083,295,13426,"0,0219722926",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,08","15,35"
"low bq, many samples",UPN2_026,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),12057,334,12476,"0,0267714011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"27,97","14,86"
"low bq, many samples",UPN2_027,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),14049,354,14475,"0,0244559585",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,05","15,11"
"low bq, many samples",UPN2_089,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),11744,295,12104,"0,0243721084",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,83","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),13731,265,14089,"0,0188089999",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"29,21","15,44"
"low bq, many samples",UPN2_028,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),10107,264,10436,"0,0252970487",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"27,98","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),10782,205,11055,"0,0185436454",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"29,21","15,6"
"low bq, low freq, many artifacts, many samples",UPN2_044,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),3126,54,3223,"0,0167545765",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,96","15,26"
"low bq, many samples",UPN2_029,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),12312,316,12690,"0,0249014972",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,04","14,97"
"low bq, many samples",UPN2_030,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),11963,307,12316,"0,0249269243",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,07","15,14"
"low bq, many samples",UPN2_031,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),7302,204,7553,"0,0270091354",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,11","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_005,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),3172,40,3228,"0,0123915737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"29,58","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_045,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),11320,197,11582,"0,0170091521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"29,25","14,88"
"low bq, many samples",UPN2_032,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),4966,159,5140,"0,0309338521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,28,"15,03"
"low bq, low freq, many artifacts, many samples",UPN2_046,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),16344,284,16766,"0,0169390433",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"29,2","15,46"
"low bq, many samples",UPN2_033,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),9063,232,9339,"0,0248420602",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,06","15,12"
"low bq, many samples",UPN2_034,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),3650,109,3781,"0,0288283523",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"27,91","15,72"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),18903,349,19368,"0,0180194135",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"29,26","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_048,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),4455,83,4564,"0,0181858019",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"29,19","15,29"
"low bq, many samples",UPN2_035,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),19272,558,19945,"0,0279769366",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,13","15,11"
"low bq, many samples",UPN2_036,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),16571,429,17074,"0,0251259225",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,1","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),11419,217,11740,"0,018483816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"29,26","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_050,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),15165,281,15554,"0,0180660923",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"29,18","14,99"
"low bq, many samples",UPN2_037,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),14601,405,15123,"0,0267804007",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"27,97","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),13534,252,13888,"0,0181451613",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"29,29","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_052,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),13123,259,13483,"0,0192093748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"29,25","14,99"
"low bq, many samples",UPN2_038,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),20061,527,20702,"0,0254564776",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,05","14,97"
"low bq, many samples",UPN2_039,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),22741,630,23506,"0,0268016677",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,04","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_053,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),17246,319,17691,"0,0180317676",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"29,17","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_054,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),11236,204,11517,"0,0177129461",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"29,15","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_007,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),23917,264,24328,"0,0108516935",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"29,49","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_008,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),31516,423,32100,"0,0131775701",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"29,44","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_009,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),24906,294,25317,"0,0116127503",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"29,54","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_010,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),14930,166,15177,"0,010937603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"29,33","15,97"
"low bq, low freq, many artifacts, many samples",UPN2_011,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),17452,199,17740,"0,0112175874",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"29,45","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_055,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),16961,328,17397,"0,0188538254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"29,21","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_056,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),4542,83,4643,"0,017876373",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"29,2","15,54"
"low bq, low freq, many artifacts, many samples",UPN2_090,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),7554,157,7757,"0,0202397834",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,81","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_057,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),16429,288,16873,"0,0170686896",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"29,06","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_058,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),23274,408,23829,"0,0171219942",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"29,27","15,53"
"low bq, many samples, no database",UPN2_059,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),1838,205,2062,"0,0994180407",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,"0,047",Damaging,"27,36","16,98"
"low bq, low freq, many artifacts, many samples",UPN2_012,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),10870,136,11064,"0,0122921186",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"29,42","14,82"
"low bq, many samples",UPN2_060,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),4208,417,4668,"0,0893316195",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"27,33","16,4"
"low bq, many samples",UPN2_040,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),20647,522,21293,"0,0245150989",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,08","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_013,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),6478,87,6612,"0,0131578947",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"29,61","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_091,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),8625,184,8839,"0,0208168345",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,9","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_092,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),5153,111,5285,"0,0210028382",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,84","15,76"
"low bq, low freq, many artifacts, many samples",UPN2_093,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),2662,57,2733,"0,020856202",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,96","14,23"
"low bq, many samples",UPN2_061,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),4935,453,5423,"0,0835330998",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"27,32","16,42"
"low bq, many samples, no database",UPN2_062,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),6228,626,6886,"0,0909090909",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,"0,047",Damaging,"27,51","16,32"
"low bq, many samples",UPN2_063,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),4539,467,5018,"0,0930649661",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"27,76","16,15"
"low bq, many samples",UPN2_064,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),2990,307,3306,"0,092861464",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"27,41","16,33"
"low bq, many samples",UPN2_065,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),1601,140,1757,"0,0796812749",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"27,89","15,95"
"low bq, many samples",UPN2_066,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),1695,154,1857,"0,0829294561",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"27,61","15,99"
"low bq, many samples",UPN2_067,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),2456,235,2707,"0,086811969",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"27,67","16,49"
"low bq, many samples",UPN2_068,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),2936,326,3280,"0,0993902439",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"27,42","16,2"
"low bq, many samples, no database",UPN2_069,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),4262,440,4728,"0,0930626058",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,"0,047",Damaging,"27,44","16,15"
"low bq, many samples",UPN2_070,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),2987,327,3343,"0,0978163326",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"27,49","16,09"
"low bq, many samples, no database",UPN2_071,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),6354,622,7014,"0,0886797833",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,"0,047",Damaging,"27,52","16,87"
"low bq, many samples, no database",UPN2_072,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),5952,593,6583,"0,0900805104",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,"0,047",Damaging,"27,55","16,57"
"low bq, many samples",UPN2_073,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),3466,357,3837,"0,0930414386",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"27,69","16,51"
"low bq, many samples",UPN2_074,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),1967,209,2186,"0,0956084172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"27,49","16,61"
"low bq, many samples",UPN2_075,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),7409,723,8168,"0,0885161606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"27,6","16,09"
"low bq, many samples",UPN2_076,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),4322,428,4772,"0,0896898575",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"27,38","16,92"
"low bq, many samples",UPN2_077,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),3705,352,4078,"0,086316822",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"27,64","16,12"
"low bq, many samples, no database",UPN2_078,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),5672,574,6275,"0,0914741036",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,"0,047",Damaging,"27,43","16,72"
"low bq, many samples, no database",UPN2_079,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),3671,347,4034,"0,0860188399",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,"0,047",Damaging,"27,43","16,14"
"low bq, many samples",UPN2_080,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),6268,639,6945,"0,0920086393",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"27,6","16,51"
"low bq, many samples",UPN2_081,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),6771,698,7515,"0,0928809049",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"27,66","16,47"
"low bq, many samples, no database",UPN2_082,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),3391,320,3722,"0,0859752821",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,"0,047",Damaging,"27,54","16,23"
"low bq, many samples",UPN2_083,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),5295,570,5888,"0,0968070652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"27,44","16,38"
"low bq, many samples",UPN2_084,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),6106,639,6779,"0,0942616905",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"27,5","16,31"
"low bq, many samples",UPN2_085,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),2772,260,3049,"0,0852738603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"27,89","16,2"
"low bq, many samples",UPN2_086,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),1714,195,1922,"0,1014568158",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"27,41","16,37"
"low bq, many samples, no database",UPN2_087,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),5104,501,5632,"0,0889559659",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,"0,047",Damaging,"27,54","16,51"
"low bq, many samples, no database",UPN2_088,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),3085,285,3379,"0,0843444806",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,"0,047",Damaging,"27,37","16,46"
"low bq, many samples",UPN2_094,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),11008,254,11311,"0,0224560163",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,79","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_095,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),10554,233,10830,"0,0215143121",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,8","14,85"
"low bq, many samples",UPN2_096,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),10884,248,11179,"0,022184453",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,91","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_097,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),10275,221,10534,"0,0209796848",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,9","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_098,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),10656,237,10947,"0,0216497671",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,91","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_099,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),6151,124,6295,"0,0196981732",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,76","15,3"
"low bq, low freq, many artifacts, many samples",UPN2_100,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),11345,220,11624,"0,0189263593",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,29,"14,7"
"low bq, many samples",UPN2_101,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),9185,219,9470,"0,02312566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,83","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_102,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),11060,245,11368,"0,0215517241",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,85","14,78"
"low bq, many samples",UPN2_103,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),11257,276,11579,"0,0238362553",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,77","15,4"
"low bq, many samples",UPN2_104,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),12781,293,13137,"0,0223034178",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,84","15,05"
"low bq, many samples",UPN2_105,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),10723,249,11014,"0,0226075903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,79","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_106,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),13346,275,13680,"0,0201023392",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,79","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_107,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),19942,425,20462,"0,0207702082",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,82","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_108,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),17005,352,17437,"0,0201869588",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,91","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_109,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),16109,342,16528,"0,0206921588",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,72","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_110,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),14833,329,15219,"0,0216177147",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,78","14,74"
low bq,UPN2_111,4,106164851,T,G,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu1240Arg/c.3719T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),14760,356,15187,"0,0234411009",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,03",Deleterious,47,Damaging,"28,85","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106164859,A,T,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys1243*/c.3727A>T|2002|TET2|protein_coding|CODING|ENST00000380013|6|T),5402,59,5487,"0,0107526882",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,72","19,54"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106164859,A,T,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys1243*/c.3727A>T|2002|TET2|protein_coding|CODING|ENST00000380013|6|T),9442,105,9601,"0,0109363608",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,84","19,48"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106164859,A,T,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys1243*/c.3727A>T|2002|TET2|protein_coding|CODING|ENST00000380013|6|T),6794,75,6906,"0,0108601216",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,66","18,71"
"low bq, low freq, many artifacts",UPN2_054,4,106164859,A,T,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys1243*/c.3727A>T|2002|TET2|protein_coding|CODING|ENST00000380013|6|T),5599,60,5720,"0,0104895105",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,72","18,38"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106164860,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys1243Ile/c.3728A>T|2002|TET2|protein_coding|CODING|ENST00000380013|6|T),5414,56,5487,"0,0102059413",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,"0,01",Damaging,"32,16","17,2"
"low bq, low freq, many artifacts, many samples",UPN2_055,4,106164860,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys1243Ile/c.3728A>T|2002|TET2|protein_coding|CODING|ENST00000380013|6|T),8529,94,8654,"0,0108620291",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,"0,01",Damaging,"32,26","19,41"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106164861,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys1243Asn/c.3729A>T|2002|TET2|protein_coding|CODING|ENST00000380013|6|T),6890,81,7016,"0,0115450399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,"4,03E-005",NO,NO,"-1,15",Neutral,72,Tolerated,"32,02","17,94"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106164861,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys1243Asn/c.3729A>T|2002|TET2|protein_coding|CODING|ENST00000380013|6|T),5384,79,5487,"0,0143976672",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,"4,03E-005",NO,NO,"-1,15",Neutral,72,Tolerated,"32,1","16,52"
"low bq, low freq, many artifacts, many samples",UPN2_045,4,106164861,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys1243Asn/c.3729A>T|2002|TET2|protein_coding|CODING|ENST00000380013|6|T),5672,59,5770,"0,0102253033",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,"4,03E-005",NO,NO,"-1,15",Neutral,72,Tolerated,"31,92","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_046,4,106164861,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys1243Asn/c.3729A>T|2002|TET2|protein_coding|CODING|ENST00000380013|6|T),8200,95,8340,"0,0113908873",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,"4,03E-005",NO,NO,"-1,15",Neutral,72,Tolerated,"31,91","16,32"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106164861,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys1243Asn/c.3729A>T|2002|TET2|protein_coding|CODING|ENST00000380013|6|T),9415,122,9601,"0,0127070097",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,"4,03E-005",NO,NO,"-1,15",Neutral,72,Tolerated,"32,13","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_048,4,106164861,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys1243Asn/c.3729A>T|2002|TET2|protein_coding|CODING|ENST00000380013|6|T),2235,28,2272,"0,0123239437",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,"4,03E-005",NO,NO,"-1,15",Neutral,72,Tolerated,"32,09","16,21"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106164861,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys1243Asn/c.3729A>T|2002|TET2|protein_coding|CODING|ENST00000380013|6|T),5724,67,5835,"0,0114824336",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,"4,03E-005",NO,NO,"-1,15",Neutral,72,Tolerated,"32,25","17,24"
"low bq, low freq, many artifacts, many samples",UPN2_050,4,106164861,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys1243Asn/c.3729A>T|2002|TET2|protein_coding|CODING|ENST00000380013|6|T),7587,91,7731,"0,0117707929",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,"4,03E-005",NO,NO,"-1,15",Neutral,72,Tolerated,"31,84","17,44"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106164861,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys1243Asn/c.3729A>T|2002|TET2|protein_coding|CODING|ENST00000380013|6|T),6768,83,6905,"0,0120202752",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,"4,03E-005",NO,NO,"-1,15",Neutral,72,Tolerated,"31,95","17,2"
"low bq, low freq, many artifacts, many samples",UPN2_054,4,106164861,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys1243Asn/c.3729A>T|2002|TET2|protein_coding|CODING|ENST00000380013|6|T),5618,68,5720,"0,0118881119",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,"4,03E-005",NO,NO,"-1,15",Neutral,72,Tolerated,"31,75","15,85"
"low bq, low freq, many artifacts, many samples",UPN2_055,4,106164861,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys1243Asn/c.3729A>T|2002|TET2|protein_coding|CODING|ENST00000380013|6|T),8506,100,8654,"0,0115553501",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,"4,03E-005",NO,NO,"-1,15",Neutral,72,Tolerated,"31,91","16,63"
"low bq, low freq, many artifacts, many samples",UPN2_056,4,106164861,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys1243Asn/c.3729A>T|2002|TET2|protein_coding|CODING|ENST00000380013|6|T),2255,27,2307,"0,0117035111",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,"4,03E-005",NO,NO,"-1,15",Neutral,72,Tolerated,"31,76","15,3"
"low bq, low freq, many artifacts, many samples",UPN2_057,4,106164861,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys1243Asn/c.3729A>T|2002|TET2|protein_coding|CODING|ENST00000380013|6|T),8235,97,8391,"0,0115600048",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,"4,03E-005",NO,NO,"-1,15",Neutral,72,Tolerated,"31,93","15,69"
"low bq, low freq, many artifacts, many samples",UPN2_058,4,106164861,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys1243Asn/c.3729A>T|2002|TET2|protein_coding|CODING|ENST00000380013|6|T),11655,133,11846,"0,0112274185",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,"4,03E-005",NO,NO,"-1,15",Neutral,72,Tolerated,"32,05","15,92"
"low bq, low freq, many artifacts",UPN2_069,4,106164861,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys1243Asn/c.3729A>T|2002|TET2|protein_coding|CODING|ENST00000380013|6|T),2316,24,2357,"0,0101824353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,"4,03E-005",NO,NO,"-1,15",Neutral,72,Tolerated,"31,35","18,42"
"low freq, many artifacts",UPN2_085,4,106164869,C,T,missense_variant(MODERATE|MISSENSE|tCg/tTg|p.Ser1246Leu/c.3737C>T|2002|TET2|protein_coding|CODING|ENST00000380013|6|T),1495,20,1521,"0,0131492439",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,11",Deleterious,"0,003",Damaging,"33,95","33,85"
"low freq, many artifacts",UPN2_048,4,106164891,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg1253Ser/c.3759G>T|2002|TET2|protein_coding|CODING|ENST00000380013|6|T),2234,38,2276,"0,0166959578",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,14",Tolerated,"33,94","30,89"
"low freq, many artifacts",UPN2_048,4,106164892,A,T,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys1254*/c.3760A>T|2002|TET2|protein_coding|CODING|ENST00000380013|6|T),2222,43,2276,"0,0188927944",0,0,0,0,1,0,0,1,2,NO,NO,COSM110776,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,9","29,95"
"low bq, low freq, many artifacts",UPN2_045,4,106164893,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys1254Ile/c.3761A>T|2002|TET2|protein_coding|CODING|ENST00000380013|6|T),5675,65,5776,"0,0112534626",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,72",Deleterious,1,Damaging,"34,61","23,57"
"low freq, many artifacts",UPN2_006,4,106164894,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys1254Asn/c.3762A>T|2002|TET2|protein_coding|CODING|ENST00000380013|6|T),5749,69,5837,"0,011821141",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,19",Deleterious,"0,075",Tolerated,"32,95","27,65"
"low bq, low freq, many artifacts",UPN2_056,4,106164894,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys1254Asn/c.3762A>T|2002|TET2|protein_coding|CODING|ENST00000380013|6|T),2255,30,2310,"0,012987013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,19",Deleterious,75,Tolerated,"32,13","16,93"
"low freq, many artifacts",UPN2_006,4,106164902,C,T,missense_variant(MODERATE|MISSENSE|aCg/aTg|p.Thr1257Met/c.3770C>T|2002|TET2|protein_coding|CODING|ENST00000380013|6|T),5764,69,5838,"0,0118191161",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,24",Neutral,"0,053",Tolerated,"35,14","32,16"
"low freq, many artifacts",UPN2_044,4,106164907,A,G,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr1259Ala/c.3775A>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),1588,22,1614,"0,0136307311",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,62",Deleterious,"0,001",Damaging,"34,28",36
"low freq, many artifacts",UPN2_044,4,106164910,A,T,missense_variant(MODERATE|MISSENSE|Aat/Tat|p.Asn1260Tyr/c.3778A>T|2002|TET2|protein_coding|CODING|ENST00000380013|6|T),1572,27,1615,"0,0167182663",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,71",Deleterious,"0,001",Damaging,"34,3","29,22"
"low bq, low freq, many artifacts, many samples",UPN2_056,4,106164910,A,T,missense_variant(MODERATE|MISSENSE|Aat/Tat|p.Asn1260Tyr/c.3778A>T|2002|TET2|protein_coding|CODING|ENST00000380013|6|T),2282,24,2312,"0,0103806228",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,71",Deleterious,1,Damaging,"34,28","21,29"
"low bq, low freq, many artifacts, many samples",UPN2_058,4,106164910,A,T,missense_variant(MODERATE|MISSENSE|Aat/Tat|p.Asn1260Tyr/c.3778A>T|2002|TET2|protein_coding|CODING|ENST00000380013|6|T),11692,119,11865,"0,0100294985",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,71",Deleterious,1,Damaging,"34,27","21,55"
"low bq, many samples",UPN2_044,4,106164923,C,T,missense_variant(MODERATE|MISSENSE|gCc/gTc|p.Ala1264Val/c.3791C>T|2002|TET2|protein_coding|CODING|ENST00000380013|6|T),1570,44,1617,"0,0272108844",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,84",Deleterious,3,Damaging,"34,49","26,8"
"inspected, many artifacts",UPN2_044,4,106164926,T,G,missense_variant(MODERATE|MISSENSE|tTg/tGg|p.Leu1265Trp/c.3794T>G|2002|TET2|protein_coding|CODING|ENST00000380013|6|G),1573,35,1617,"0,0216450216",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,9",Deleterious,"0,006",Damaging,"34,18","34,2"
"low freq, many artifacts",UPN2_044,4,106180781,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr1270Ile/c.3809C>T|2002|TET2|protein_coding|CODING|ENST00000380013|7|T),2378,37,2417,"0,0153082333",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,28",Deleterious,"0,001",Damaging,"35,51","34,78"
"low freq, CT region, inspected",UPN2_049,4,106180822,T,TC,frameshift_variant(HIGH||ttc/Cttc|p.Phe1285fs/c.3852dupC|2002|TET2|protein_coding|CODING|ENST00000380013|7|TC|INFO_REALIGN_3_PRIME),5484,121,5503,"0,0219880065",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,18",NA
"low bq, low freq, many artifacts, many samples",UPN2_014,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),17683,209,17935,"0,0116531921",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,"29,51","16,26"
"low bq, low freq, many artifacts, many samples",UPN2_015,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),26199,377,26620,"0,014162284",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,"29,38","15,97"
"low bq, low freq, many artifacts, many samples",UPN2_016,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),11871,161,12051,"0,0133598871",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,"29,65","16,43"
"low bq, low freq, many artifacts, many samples",UPN2_017,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),7176,81,7268,"0,0111447441",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,"29,54","15,64"
"low bq, low freq, many artifacts, many samples",UPN2_018,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),12567,152,12755,"0,0119168953",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,"29,54","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_019,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),14799,200,15033,"0,0133040644",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,"29,48","15,81"
"low bq, low freq, many artifacts, many samples",UPN2_020,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),10787,120,10940,"0,0109689214",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,"29,61","15,91"
"low bq, low freq, many artifacts, many samples",UPN2_021,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),13037,133,13205,"0,0100719424",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,"29,63","15,95"
"low bq, low freq, many artifacts, many samples",UPN2_022,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),18666,250,18960,"0,013185654",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,"29,47","15,5"
"low bq, low freq, many artifacts, many samples",UPN2_023,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),19934,303,20281,"0,0149400917",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,"29,37","15,34"
"low bq, low freq, many artifacts, many samples",UPN2_024,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),9150,124,9296,"0,0133390706",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,"29,56","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_025,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),20988,253,21304,"0,0118757041",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,"29,57","15,58"
"low bq, low freq, many artifacts, many samples",UPN2_026,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),21080,281,21426,"0,0131149071",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,"29,5","15,63"
"low bq, low freq, many artifacts, many samples",UPN2_027,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),24016,375,24439,"0,0153443267",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,"29,51","15,77"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),13199,176,13410,"0,0131245339",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,"30,01","16,18"
"low bq, low freq, many artifacts, many samples",UPN2_028,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),18320,286,18644,"0,0153400558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,"29,38","17,08"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),16579,229,16867,"0,0135768068",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,"30,07",16
"low bq, low freq, many artifacts, many samples",UPN2_044,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),4681,64,4760,"0,0134453782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,"30,04","15,62"
"low bq, low freq, many artifacts, many samples",UPN2_029,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),20246,265,20558,"0,012890359",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,"29,5","15,95"
"low bq, low freq, many artifacts, many samples",UPN2_030,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),19097,247,19384,"0,012742468",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,"29,51","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_031,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),12529,151,12704,"0,0118860202",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,"29,54","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_045,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),18292,277,18636,"0,0148637047",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,"30,08","16,43"
"low bq, low freq, many artifacts, many samples",UPN2_032,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),8573,132,8729,"0,0151220071",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,"29,45","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_046,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),24319,366,24761,"0,0147813093",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,"30,01","15,96"
"low bq, low freq, many artifacts, many samples",UPN2_033,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),16675,212,16929,"0,0125228897",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,"29,71","16,89"
"low bq, low freq, many artifacts, many samples",UPN2_034,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),6073,69,6154,"0,0112122197",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,"29,55","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),12797,171,12993,"0,0131609328",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,"30,1","15,82"
"low bq, low freq, many artifacts, many samples",UPN2_035,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),22610,305,22964,"0,0132816582",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,"29,52","16,02"
"low bq, low freq, many artifacts, many samples",UPN2_036,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),20397,280,20721,"0,0135128613",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,"29,45","15,98"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),10606,164,10807,"0,0151753493",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,"30,09","16,3"
"low bq, low freq, many artifacts, many samples",UPN2_050,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),21370,326,21766,"0,0149774878",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,"29,88","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_037,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),23813,322,24200,"0,0133057851",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,"29,45","16,11"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),21227,244,21534,"0,0113309185",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,"30,11","16,13"
"low bq, low freq, many artifacts, many samples",UPN2_052,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),20719,317,21091,"0,0150301076",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,"29,95","15,74"
"low bq, low freq, many artifacts, many samples",UPN2_038,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),34168,509,34755,"0,0146453748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,"29,47","16,04"
"low bq, low freq, many artifacts, many samples",UPN2_039,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),29766,416,30275,"0,0137407102",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,"29,48","15,62"
"low bq, low freq, many artifacts, many samples",UPN2_053,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),28684,452,29236,"0,0154603913",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,"29,93","15,64"
"low bq, low freq, many artifacts, many samples",UPN2_054,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),22134,362,22566,"0,0160418328",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,"29,87","15,58"
"low bq, low freq, many artifacts, many samples",UPN2_055,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),25526,368,25987,"0,0141609266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,30,"16,61"
"low bq, low freq, many artifacts, many samples",UPN2_057,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),28715,350,29146,"0,0120085089",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,"30,05","15,87"
"low bq, low freq, many artifacts, many samples",UPN2_058,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),31819,422,32338,"0,0130496629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,"30,1","16,66"
"low bq, low freq, many artifacts",UPN2_040,4,106180855,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1295Asn/c.3883T>A|2002|TET2|protein_coding|CODING|ENST00000380013|7|A),21008,293,21346,"0,0137262251",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,35",Deleterious,0,Damaging,"29,56","16,15"
"inspected, many artifacts",UPN2_056,4,106180862,G,T,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly1297Val/c.3890G>T|2002|TET2|protein_coding|CODING|ENST00000380013|7|T),1001,21,1022,"0,0205479452",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,05",Deleterious,0,Damaging,"32,13","32,48"
"low freq, many artifacts",UPN2_044,4,106180874,C,T,missense_variant(MODERATE|MISSENSE|gCc/gTc|p.Ala1301Val/c.3902C>T|2002|TET2|protein_coding|CODING|ENST00000380013|7|T),4680,83,4789,"0,0173313844",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,44",Deleterious,"0,001",Damaging,"31,05","32,22"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106180900,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys1310*/c.3928A>T|2002|TET2|protein_coding|CODING|ENST00000380013|7|T),6580,68,6693,"0,0101598685",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,94","17,87"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106180900,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys1310*/c.3928A>T|2002|TET2|protein_coding|CODING|ENST00000380013|7|T),8291,88,8409,"0,010464978",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,03","17,17"
"low bq, low freq, many artifacts, many samples",UPN2_046,4,106180900,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys1310*/c.3928A>T|2002|TET2|protein_coding|CODING|ENST00000380013|7|T),12176,156,12370,"0,012611156",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,87","17,1"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106180900,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys1310*/c.3928A>T|2002|TET2|protein_coding|CODING|ENST00000380013|7|T),6404,88,6510,"0,0135176651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,92","16,48"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106180900,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys1310*/c.3928A>T|2002|TET2|protein_coding|CODING|ENST00000380013|7|T),5316,68,5403,"0,0125856006",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,87","17,37"
"low bq, low freq, many artifacts, many samples",UPN2_050,4,106180900,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys1310*/c.3928A>T|2002|TET2|protein_coding|CODING|ENST00000380013|7|T),10710,119,10876,"0,0109415226",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,83","16,29"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106180900,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys1310*/c.3928A>T|2002|TET2|protein_coding|CODING|ENST00000380013|7|T),10589,119,10742,"0,0110780115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,96","15,9"
"low bq, low freq, many artifacts, many samples",UPN2_053,4,106180900,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys1310*/c.3928A>T|2002|TET2|protein_coding|CODING|ENST00000380013|7|T),14386,162,14617,"0,0110829856",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,68","17,44"
"low bq, low freq, many artifacts, many samples",UPN2_054,4,106180900,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys1310*/c.3928A>T|2002|TET2|protein_coding|CODING|ENST00000380013|7|T),11097,119,11253,"0,0105749578",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,77","16,67"
"low bq, low freq, many artifacts, many samples",UPN2_055,4,106180900,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys1310*/c.3928A>T|2002|TET2|protein_coding|CODING|ENST00000380013|7|T),12783,157,12983,"0,0120927367",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,84","17,68"
"low bq, low freq, many artifacts, many samples",UPN2_057,4,106180900,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys1310*/c.3928A>T|2002|TET2|protein_coding|CODING|ENST00000380013|7|T),14313,154,14542,"0,0105900151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,87","17,95"
"low bq, low freq, many artifacts",UPN2_058,4,106180900,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys1310*/c.3928A>T|2002|TET2|protein_coding|CODING|ENST00000380013|7|T),15866,202,16124,"0,0125279087",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,94","16,81"
"low bq, low freq, many artifacts",UPN2_042,4,106180901,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys1310Met/c.3929A>T|2002|TET2|protein_coding|CODING|ENST00000380013|7|T),6600,67,6695,"0,0100074683",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,56",Deleterious,1,Damaging,"33,89","21,18"
"low bq, low freq, many artifacts, many samples",UPN2_044,4,106180922,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys1317Ile/c.3950A>T|2002|TET2|protein_coding|CODING|ENST00000380013|7|T),2347,29,2381,"0,0121797564",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,59",Deleterious,2,Damaging,"33,62","17,52"
"low bq, low freq, many artifacts, many samples",UPN2_045,4,106180922,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys1317Ile/c.3950A>T|2002|TET2|protein_coding|CODING|ENST00000380013|7|T),9191,97,9330,"0,0103965702",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,59",Deleterious,2,Damaging,"33,73","16,87"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106180922,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys1317Ile/c.3950A>T|2002|TET2|protein_coding|CODING|ENST00000380013|7|T),6419,77,6519,"0,0118116276",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,59",Deleterious,2,Damaging,"33,6","17,53"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106180922,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys1317Ile/c.3950A>T|2002|TET2|protein_coding|CODING|ENST00000380013|7|T),5324,58,5410,"0,0107208872",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,59",Deleterious,2,Damaging,"33,75","17,66"
"low bq, low freq, many artifacts, many samples",UPN2_050,4,106180922,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys1317Ile/c.3950A>T|2002|TET2|protein_coding|CODING|ENST00000380013|7|T),10734,120,10895,"0,0110142267",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,59",Deleterious,2,Damaging,"33,61","17,93"
"low bq, low freq, many artifacts",UPN2_053,4,106180922,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys1317Ile/c.3950A>T|2002|TET2|protein_coding|CODING|ENST00000380013|7|T),14432,148,14636,"0,0101120525",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,59",Deleterious,2,Damaging,"33,69","17,41"
inspected,UPN2_051,4,106180926,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu1318Asp/c.3954G>C|2002|TET2|protein_coding|CODING|ENST00000380013|7|C),8760,1918,10770,"0,1780872795",1,0,0,0,0,0,0,0,1,NO,NO,COSM4383929,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,3,Damaging,"32,92","33,51"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106182960,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1333Ile/c.3999G>T|2002|TET2|protein_coding|CODING|ENST00000380013|8|T),22922,237,23231,"0,0102018854",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,11",Neutral,319,Tolerated,"31,5","18,51"
"low bq, low freq, many artifacts, many samples",UPN2_056,4,106182960,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1333Ile/c.3999G>T|2002|TET2|protein_coding|CODING|ENST00000380013|8|T),5768,61,5839,"0,0104469943",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,11",Neutral,319,Tolerated,"31,54","16,95"
"low bq, low freq, many artifacts, many samples",UPN2_064,4,106182960,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1333Ile/c.3999G>T|2002|TET2|protein_coding|CODING|ENST00000380013|8|T),30662,319,31078,"0,0102644958",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,11",Neutral,319,Tolerated,"31,19","15,17"
"low bq, low freq, many artifacts, many samples",UPN2_066,4,106182960,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1333Ile/c.3999G>T|2002|TET2|protein_coding|CODING|ENST00000380013|8|T),88537,923,89698,"0,0102900845",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,11",Neutral,319,Tolerated,"31,13","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_071,4,106182960,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1333Ile/c.3999G>T|2002|TET2|protein_coding|CODING|ENST00000380013|8|T),26534,269,26860,"0,010014892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,11",Neutral,319,Tolerated,"31,12","15,76"
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106182960,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1333Ile/c.3999G>T|2002|TET2|protein_coding|CODING|ENST00000380013|8|T),33139,349,33584,"0,0103918533",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,11",Neutral,319,Tolerated,"31,12","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106182960,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1333Ile/c.3999G>T|2002|TET2|protein_coding|CODING|ENST00000380013|8|T),27138,275,27481,"0,0100069139",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,11",Neutral,319,Tolerated,"31,18","14,92"
"low bq, low freq, many artifacts",UPN2_082,4,106182960,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1333Ile/c.3999G>T|2002|TET2|protein_coding|CODING|ENST00000380013|8|T),72732,737,73694,"0,0100008142",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,11",Neutral,319,Tolerated,"31,17","15,05"
"low freq, many artifacts",UPN2_056,4,106182977,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys1339Ile/c.4016A>T|2002|TET2|protein_coding|CODING|ENST00000380013|8|T),2871,32,2922,"0,0109514031",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,19",Deleterious,"0,012",Damaging,"34,73","29,56"
"inspected, low freq",UPN2_056,4,106182981,TG,T,frameshift_variant(HIGH||gca/|p.Ala1341fs/c.4021delG|2002|TET2|protein_coding|CODING|ENST00000380013|8|T),2866,30,2925,"0,0102564103",0,0,0,1,1,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,27",NA
"inspected, many artifacts",UPN2_044,4,106190791,G,T,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu1357*/c.4069G>T|2002|TET2|protein_coding|CODING|ENST00000380013|9|T),814,23,841,"0,0273483948",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,35","34,87"
"low bq, low freq, many artifacts",UPN2_067,4,106190818,C,A,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg1366Ser/c.4096C>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),2138,25,2165,"0,0115473441",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,81",Deleterious,1,Damaging,"31,48","15,92"
"low freq, many artifacts",UPN2_012,4,106190818,C,T,missense_variant(MODERATE|MISSENSE|Cgt/Tgt|p.Arg1366Cys/c.4096C>T|2002|TET2|protein_coding|CODING|ENST00000380013|9|T),2361,25,2397,"0,0104297038",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,77",Deleterious,0,Damaging,"33,43","35,32"
"inspected, many artifacts",UPN2_044,4,106190819,G,T,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg1366Leu/c.4097G>T|2002|TET2|protein_coding|CODING|ENST00000380013|9|T),810,30,841,"0,0356718193",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,8",Deleterious,"0,001",Damaging,"33,94","32,53"
"low bq, low freq, many artifacts, many samples",UPN2_060,4,106190834,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1371Gly/c.4112T>G|2002|TET2|protein_coding|CODING|ENST00000380013|9|G),4998,51,5070,"0,0100591716",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,7",Deleterious,0,Damaging,"30,48","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_064,4,106190834,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1371Gly/c.4112T>G|2002|TET2|protein_coding|CODING|ENST00000380013|9|G),1994,22,2023,"0,0108749382",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,7",Deleterious,0,Damaging,"30,32","15,82"
"low bq, low freq, many artifacts, many samples",UPN2_066,4,106190834,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1371Gly/c.4112T>G|2002|TET2|protein_coding|CODING|ENST00000380013|9|G),3603,47,3664,"0,0128275109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,7",Deleterious,0,Damaging,"30,41","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_071,4,106190834,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1371Gly/c.4112T>G|2002|TET2|protein_coding|CODING|ENST00000380013|9|G),4729,53,4796,"0,0110508757",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,7",Deleterious,0,Damaging,"30,46","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106190834,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1371Gly/c.4112T>G|2002|TET2|protein_coding|CODING|ENST00000380013|9|G),3007,40,3058,"0,0130804447",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,7",Deleterious,0,Damaging,"30,39","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_074,4,106190834,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1371Gly/c.4112T>G|2002|TET2|protein_coding|CODING|ENST00000380013|9|G),2586,27,2618,"0,0103132162",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,7",Deleterious,0,Damaging,"30,45","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_075,4,106190834,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1371Gly/c.4112T>G|2002|TET2|protein_coding|CODING|ENST00000380013|9|G),6613,69,6712,"0,0102800954",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,7",Deleterious,0,Damaging,"30,43","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_077,4,106190834,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1371Gly/c.4112T>G|2002|TET2|protein_coding|CODING|ENST00000380013|9|G),4853,53,4922,"0,0107679805",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,7",Deleterious,0,Damaging,"30,6","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_078,4,106190834,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1371Gly/c.4112T>G|2002|TET2|protein_coding|CODING|ENST00000380013|9|G),5476,59,5551,"0,0106287155",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,7",Deleterious,0,Damaging,"30,53","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_083,4,106190834,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1371Gly/c.4112T>G|2002|TET2|protein_coding|CODING|ENST00000380013|9|G),8408,102,8562,"0,0119131044",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,7",Deleterious,0,Damaging,"30,35","14,55"
"low bq, low freq, many artifacts",UPN2_088,4,106190834,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1371Gly/c.4112T>G|2002|TET2|protein_coding|CODING|ENST00000380013|9|G),4866,52,4949,"0,0105071732",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,7",Deleterious,0,Damaging,"30,54",19
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106190836,A,T,missense_variant(MODERATE|MISSENSE|Act/Tct|p.Thr1372Ser/c.4114A>T|2002|TET2|protein_coding|CODING|ENST00000380013|9|T),8155,86,8267,"0,0104028063",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,81",Deleterious,3,Damaging,"32,44","18,86"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106190836,A,T,missense_variant(MODERATE|MISSENSE|Act/Tct|p.Thr1372Ser/c.4114A>T|2002|TET2|protein_coding|CODING|ENST00000380013|9|T),9370,97,9510,"0,0101997897",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,81",Deleterious,3,Damaging,"32,43","19,12"
"low bq, low freq, many artifacts, many samples",UPN2_054,4,106190836,A,T,missense_variant(MODERATE|MISSENSE|Act/Tct|p.Thr1372Ser/c.4114A>T|2002|TET2|protein_coding|CODING|ENST00000380013|9|T),9484,97,9622,"0,0100810642",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,81",Deleterious,3,Damaging,"32,54","20,18"
"low bq, low freq, many artifacts",UPN2_085,4,106190836,A,T,missense_variant(MODERATE|MISSENSE|Act/Tct|p.Thr1372Ser/c.4114A>T|2002|TET2|protein_coding|CODING|ENST00000380013|9|T),2471,26,2507,"0,0103709613",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,81",Deleterious,3,Damaging,"32,78","21,19"
"low freq, many artifacts",UPN2_044,4,106190839,G,A,missense_variant(MODERATE|MISSENSE|Gca/Aca|p.Ala1373Thr/c.4117G>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),1638,20,1661,"0,0120409392",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,"0,001",Damaging,"32,81","33,75"
"inspected, many artifacts",UPN2_006,4,106190851,T,C,missense_variant(MODERATE|MISSENSE|Ttc/Ctc|p.Phe1377Leu/c.4129T>C|2002|TET2|protein_coding|CODING|ENST00000380013|9|C),5006,106,5125,"0,0206829268",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,69",Deleterious,"0,001",Damaging,"34,19","33,8"
"low freq, many artifacts",UPN2_035,4,106190854,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1378Arg/c.4132T>C|2002|TET2|protein_coding|CODING|ENST00000380013|9|C),14251,233,14517,"0,0160501481",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-11,08",Deleterious,"0,001",Damaging,"32,03","30,86"
"low freq, many artifacts",UPN2_011,4,106190854,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1378Arg/c.4132T>C|2002|TET2|protein_coding|CODING|ENST00000380013|9|C),11038,185,11249,"0,0164459063",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-11,08",Deleterious,"0,001",Damaging,"32,94","32,45"
"low freq, many artifacts",UPN2_044,4,106190862,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1380Gln/c.4140T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),1640,22,1665,"0,0132132132",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,0,Damaging,"33,93",33
"low freq, many artifacts",UPN2_012,4,106190863,GC,G,frameshift_variant(HIGH||cac/|p.His1382fs/c.4144delC|2002|TET2|protein_coding|CODING|ENST00000380013|9|G|INFO_REALIGN_3_PRIME),4693,50,4759,"0,0105064089",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,35",NA
"low freq, many artifacts",UPN2_064,4,106190864,C,A,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala1381Asp/c.4142C>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),1989,30,2029,"0,0147856087",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,75",Deleterious,"0,001",Damaging,"31,19","26,07"
"low freq, many artifacts",UPN2_063,4,106190869,A,G,missense_variant(MODERATE|MISSENSE|Aga/Gga|p.Arg1383Gly/c.4147A>G|2002|TET2|protein_coding|CODING|ENST00000380013|9|G),4547,65,4623,"0,0140601341",0,0,0,0,1,1,0,1,3,NO,NO,COSM4170030,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,45",Deleterious,"0,001",Damaging,"33,59","31,09"
inspected,UPN2_107,4,106190876,TG,T,frameshift_variant(HIGH||ttg/|p.Leu1385fs/c.4155delG|2002|TET2|protein_coding|CODING|ENST00000380013|9|T),14123,311,14515,"0,0214261109",0,0,0,1,1,0,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,65",NA
"low freq, many artifacts",UPN2_085,4,106190879,A,G,missense_variant(MODERATE|MISSENSE|cAc/cGc|p.His1386Arg/c.4157A>G|2002|TET2|protein_coding|CODING|ENST00000380013|9|G),2472,26,2512,"0,0103503185",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,36",Deleterious,"0,002",Damaging,"32,71","32,04"
"inspected, many artifacts",UPN2_056,4,106190881,A,G,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn1387Asp/c.4159A>G|2002|TET2|protein_coding|CODING|ENST00000380013|9|G),723,26,749,"0,0347129506",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,83",Deleterious,"0,015",Damaging,"33,07","33,08"
"low freq, many artifacts",UPN2_065,4,106190881,A,T,missense_variant(MODERATE|MISSENSE|Aac/Tac|p.Asn1387Tyr/c.4159A>T|2002|TET2|protein_coding|CODING|ENST00000380013|9|T),1993,21,2021,"0,0103908956",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,67",Deleterious,0,Damaging,"33,27","30,24"
"low freq, many artifacts",UPN2_050,4,106190882,A,T,missense_variant(MODERATE|MISSENSE|aAc/aTc|p.Asn1387Ile/c.4160A>T|2002|TET2|protein_coding|CODING|ENST00000380013|9|T),10129,111,10283,"0,0107945152",0,0,0,0,1,0,0,0,1,NO,NO,COSM4383941,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-8,71",Deleterious,3,Damaging,"33,86","27,74"
"low bq, low freq, many artifacts, many samples",UPN2_001,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),4258,54,4320,"0,0125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"32,56","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_015,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),15597,168,15844,"0,010603383",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"31,78","16,38"
"low bq, low freq, many artifacts, many samples",UPN2_016,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),7323,90,7451,"0,0120789156",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"31,62","16,7"
"low bq, low freq, many artifacts, many samples",UPN2_018,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),7869,82,7972,"0,010286001",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"31,83","16,48"
"low bq, low freq, many artifacts, many samples",UPN2_019,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),8673,91,8802,"0,0103385594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"31,81","15,7"
"low bq, low freq, many artifacts, many samples",UPN2_020,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),6392,74,6488,"0,011405672",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"31,79","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_002,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),5347,57,5418,"0,0105204873",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"32,76","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_022,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),10289,117,10450,"0,0111961722",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"31,67","16,59"
"low bq, low freq, many artifacts, many samples",UPN2_024,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),5072,62,5162,"0,0120108485",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"31,57","15,82"
"low bq, low freq, many artifacts, many samples",UPN2_025,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),12369,128,12533,"0,0102130376",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"31,65","16,03"
"low bq, low freq, many artifacts, many samples",UPN2_026,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),12570,141,12750,"0,0110588235",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"31,9","16,03"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),7056,79,7169,"0,011019668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"31,6","16,13"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),7825,119,7982,"0,0149085442",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"31,83","16,14"
"low bq, low freq, many artifacts, many samples",UPN2_044,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),1631,22,1663,"0,013229104",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"31,89","18,55"
"low bq, low freq, many artifacts, many samples",UPN2_029,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),11411,125,11603,"0,0107730759",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"31,75","16,5"
"low bq, low freq, many artifacts, many samples",UPN2_031,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),5982,67,6067,"0,0110433493",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"31,53","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_045,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),10184,118,10369,"0,0113800752",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"31,84","15,55"
"low bq, low freq, many artifacts, many samples",UPN2_032,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),3914,44,3989,"0,0110303334",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"31,69","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_046,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),11414,133,11597,"0,0114684832",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"31,9","15,74"
"low bq, low freq, many artifacts, many samples",UPN2_033,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),9120,120,9270,"0,0129449838",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"31,58","15,82"
"low bq, low freq, many artifacts, many samples",UPN2_034,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),3461,40,3522,"0,0113571834",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"31,96","18,67"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),8109,106,8260,"0,0128329298",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"31,58","16,85"
"low bq, low freq, many artifacts, many samples",UPN2_035,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),14242,160,14448,"0,0110741971",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"31,56","15,54"
"low bq, low freq, many artifacts, many samples",UPN2_036,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),15178,184,15429,"0,0119255947",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"31,68","16,71"
"low bq, low freq, many artifacts, many samples",UPN2_006,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),5034,64,5111,"0,0125220113",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"32,73","15,34"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),4892,60,4973,"0,0120651518",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"31,8","15,85"
"low bq, low freq, many artifacts, many samples",UPN2_050,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),10066,129,10248,"0,012587822",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"31,87","16,31"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),9317,110,9460,"0,011627907",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"31,81","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_052,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),9730,107,9885,"0,0108244815",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"31,92","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_038,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),17553,183,17835,"0,0102607233",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"31,78","16,17"
"low bq, low freq, many artifacts, many samples",UPN2_039,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),23261,275,23637,"0,0116343022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"31,79","16,62"
"low bq, low freq, many artifacts, many samples",UPN2_053,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),13173,163,13386,"0,0121769012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"31,96","15,52"
"low bq, low freq, many artifacts, many samples",UPN2_054,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),9455,104,9602,"0,0108310769",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"31,82","15,88"
"low bq, low freq, many artifacts, many samples",UPN2_007,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),12307,150,12491,"0,0120086462",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"32,54","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_008,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),16334,173,16578,"0,010435517",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"32,67","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_009,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),12032,136,12217,"0,0111320291",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"32,56","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_011,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),11030,125,11191,"0,0111696899",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"32,5","15,62"
"low bq, low freq, many artifacts, many samples",UPN2_055,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),12412,140,12598,"0,0111128751",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"31,83","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_057,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),11138,134,11337,"0,0118197054",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"31,69","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_058,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),10185,141,10376,"0,0135890517",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"31,65","16,43"
"low bq, low freq, many artifacts, many samples",UPN2_040,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),18304,194,18585,"0,0104385257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"31,74","15,39"
"low bq, low freq, many artifacts, many samples",UPN2_065,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),1981,24,2014,"0,0119165839",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"31,48","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_067,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),4192,45,4247,"0,0105957146",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"31,33","15,62"
"low bq, low freq, many artifacts, many samples",UPN2_079,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),3410,35,3453,"0,0101361135",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"31,39","17,09"
"low bq, low freq, many artifacts",UPN2_088,4,106190885,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met1388Lys/c.4163T>A|2002|TET2|protein_coding|CODING|ENST00000380013|9|A),4873,58,4949,"0,0117195393",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"31,47","16,83"
"low freq, many artifacts",UPN2_074,4,106190885,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1388Thr/c.4163T>C|2002|TET2|protein_coding|CODING|ENST00000380013|9|C),2572,28,2617,"0,010699274",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,0,Damaging,"31,71","30,82"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106190888,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln1389Leu/c.4166A>T|2002|TET2|protein_coding|CODING|ENST00000380013|9|T),3905,48,3975,"0,0120754717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,55,Tolerated,"31,89","21,44"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106190888,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln1389Leu/c.4166A>T|2002|TET2|protein_coding|CODING|ENST00000380013|9|T),4039,49,4100,"0,0119512195",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,55,Tolerated,"31,84","21,88"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106190888,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln1389Leu/c.4166A>T|2002|TET2|protein_coding|CODING|ENST00000380013|9|T),4649,51,4719,"0,0108073744",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,55,Tolerated,32,"22,25"
"low freq, many artifacts",UPN2_006,4,106190890,A,G,missense_variant(MODERATE|MISSENSE|Aat/Gat|p.Asn1390Asp/c.4168A>G|2002|TET2|protein_coding|CODING|ENST00000380013|9|G),2514,29,2556,"0,0113458529",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,83",Deleterious,"0,051",Tolerated,"33,74","33,83"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106190890,A,T,missense_variant(MODERATE|MISSENSE|Aat/Tat|p.Asn1390Tyr/c.4168A>T|2002|TET2|protein_coding|CODING|ENST00000380013|9|T),4047,42,4100,"0,0102439024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,0,Damaging,"32,36","19,74"
"low bq, low freq, many artifacts",UPN2_050,4,106190890,A,T,missense_variant(MODERATE|MISSENSE|Aat/Tat|p.Asn1390Tyr/c.4168A>T|2002|TET2|protein_coding|CODING|ENST00000380013|9|T),5033,57,5105,"0,011165524",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,68",Deleterious,0,Damaging,"32,72","21,53"
"low bq, low freq, many artifacts, many samples",UPN2_017,4,106190899,A,T,missense_variant(MODERATE|MISSENSE|Aca/Tca|p.Thr1393Ser/c.4177A>T|2002|TET2|protein_coding|CODING|ENST00000380013|9|T),2555,31,2597,"0,0119368502",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,92",Deleterious,16,Damaging,"34,36","19,42"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106190899,A,T,missense_variant(MODERATE|MISSENSE|Aca/Tca|p.Thr1393Ser/c.4177A>T|2002|TET2|protein_coding|CODING|ENST00000380013|9|T),3513,39,3568,"0,0109304933",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,92",Deleterious,16,Damaging,"33,44","17,79"
"low bq, low freq, many artifacts, many samples",UPN2_045,4,106190899,A,T,missense_variant(MODERATE|MISSENSE|Aca/Tca|p.Thr1393Ser/c.4177A>T|2002|TET2|protein_coding|CODING|ENST00000380013|9|T),5061,70,5151,"0,0135895943",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,92",Deleterious,16,Damaging,"33,49","19,46"
"low bq, low freq, many artifacts, many samples",UPN2_046,4,106190899,A,T,missense_variant(MODERATE|MISSENSE|Aca/Tca|p.Thr1393Ser/c.4177A>T|2002|TET2|protein_coding|CODING|ENST00000380013|9|T),5687,64,5779,"0,0110745804",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,92",Deleterious,16,Damaging,"33,5","17,42"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106190899,A,T,missense_variant(MODERATE|MISSENSE|Aca/Tca|p.Thr1393Ser/c.4177A>T|2002|TET2|protein_coding|CODING|ENST00000380013|9|T),2442,25,2483,"0,0100684656",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,92",Deleterious,16,Damaging,"33,39","18,08"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106190899,A,T,missense_variant(MODERATE|MISSENSE|Aca/Tca|p.Thr1393Ser/c.4177A>T|2002|TET2|protein_coding|CODING|ENST00000380013|9|T),4643,60,4720,"0,0127118644",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,92",Deleterious,16,Damaging,"33,48","17,75"
"low bq, low freq, many artifacts, many samples",UPN2_053,4,106190899,A,T,missense_variant(MODERATE|MISSENSE|Aca/Tca|p.Thr1393Ser/c.4177A>T|2002|TET2|protein_coding|CODING|ENST00000380013|9|T),6569,81,6671,"0,0121421076",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,92",Deleterious,16,Damaging,"33,48","19,15"
"low bq, low freq, many artifacts, many samples",UPN2_054,4,106190899,A,T,missense_variant(MODERATE|MISSENSE|Aca/Tca|p.Thr1393Ser/c.4177A>T|2002|TET2|protein_coding|CODING|ENST00000380013|9|T),4716,50,4781,"0,0104580632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,92",Deleterious,16,Damaging,"33,4","16,78"
"low bq, low freq, many artifacts, many samples",UPN2_055,4,106190899,A,T,missense_variant(MODERATE|MISSENSE|Aca/Tca|p.Thr1393Ser/c.4177A>T|2002|TET2|protein_coding|CODING|ENST00000380013|9|T),6174,77,6277,"0,0122670065",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,92",Deleterious,16,Damaging,"33,45","15,73"
"low bq, low freq, many artifacts, many samples",UPN2_057,4,106190899,A,T,missense_variant(MODERATE|MISSENSE|Aca/Tca|p.Thr1393Ser/c.4177A>T|2002|TET2|protein_coding|CODING|ENST00000380013|9|T),5553,62,5645,"0,0109831709",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,92",Deleterious,16,Damaging,"33,41","17,35"
"low bq, low freq, many artifacts",UPN2_058,4,106190899,A,T,missense_variant(MODERATE|MISSENSE|Aca/Tca|p.Thr1393Ser/c.4177A>T|2002|TET2|protein_coding|CODING|ENST00000380013|9|T),5086,57,5162,"0,0110422317",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,92",Deleterious,16,Damaging,"33,43","14,86"
"low bq, low freq, many artifacts",UPN2_062,4,106190900,C,G,missense_variant(MODERATE|MISSENSE|aCa/aGa|p.Thr1393Arg/c.4178C>G|2002|TET2|protein_coding|CODING|ENST00000380013|9|G),2553,27,2588,"0,0104327666",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,88",Deleterious,0,Damaging,"32,88","14,26"
inspected,UPN2_044,4,106190900,C,T,missense_variant(MODERATE|MISSENSE|aCa/aTa|p.Thr1393Ile/c.4178C>T|2002|TET2|protein_coding|CODING|ENST00000380013|9|T),781,40,824,"0,0485436893",0,0,0,0,1,0,0,1,2,NO,NO,COSM4383944,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,88",Deleterious,0,Damaging,"32,53","34,1"
"low freq, many artifacts",UPN2_041,4,106193727,A,T,missense_variant(MODERATE|MISSENSE|Act/Tct|p.Thr1397Ser/c.4189A>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),1357,23,1383,"0,0166305134",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,"0,011",Damaging,"35,31",36
"low freq, many artifacts",UPN2_041,4,106193740,A,T,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu1401Val/c.4202A>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),1351,27,1383,"0,0195227766",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,-6,Deleterious,"0,001",Damaging,"35,49","34,22"
"inspected, many artifacts",UPN2_044,4,106193781,C,T,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu1415Phe/c.4243C>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),1540,40,1584,"0,0252525253",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,4",Deleterious,"0,123",Tolerated,"34,87","35,6"
"low freq, many artifacts",UPN2_041,4,106193782,T,C,missense_variant(MODERATE|MISSENSE|cTt/cCt|p.Leu1415Pro/c.4244T>C|2002|TET2|protein_coding|CODING|ENST00000380013|10|C),1358,21,1383,"0,0151843818",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,41",Deleterious,0,Damaging,"34,77","34,33"
"low freq, many artifacts",UPN2_012,4,106193789,TC,T,frameshift_variant(HIGH||ctg/|p.Leu1418fs/c.4252delC|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),6058,109,6182,"0,0176318344",0,0,0,1,1,0,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,13",NA
"low bq, low freq, many artifacts",UPN2_041,4,106193812,A,T,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp1425Val/c.4274A>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),2688,30,2736,"0,0109649123",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,3",Deleterious,4,Damaging,"32,23","21,8"
"low freq, many artifacts",UPN2_044,4,106193817,G,A,missense_variant(MODERATE|MISSENSE|Gat/Aat|p.Asp1427Asn/c.4279G>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),3097,36,3141,"0,0114613181",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,55",Deleterious,"0,01",Damaging,"32,97","32,31"
"low freq, many artifacts",UPN2_041,4,106193818,A,G,missense_variant(MODERATE|MISSENSE|gAt/gGt|p.Asp1427Gly/c.4280A>G|2002|TET2|protein_coding|CODING|ENST00000380013|10|G),2670,54,2737,"0,019729631",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,38",Deleterious,"0,002",Damaging,"33,83","33,7"
"low freq, many artifacts",UPN2_056,4,106193830,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1431Asn/c.4292G>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),6804,69,6882,"0,0100261552",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,11,Damaging,"34,18","32,71"
"low freq, many artifacts",UPN2_002,4,106193838,GC,G,frameshift_variant(HIGH||gct/|p.Ala1434fs/c.4301delC|2002|TET2|protein_coding|CODING|ENST00000380013|10|G),10716,1277,12026,"0,1061865957",1,1,0,1,0,1,0,1,5,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,76",NA
"low bq, low freq, many artifacts, many samples",UPN2_001,4,106193841,C,A,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln1435Lys/c.4303C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),9519,110,9662,"0,0113848065",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-3,Deleterious,1,Damaging,"29,84","14,12"
"low bq, low freq, many artifacts, many samples",UPN2_003,4,106193841,C,A,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln1435Lys/c.4303C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),2393,27,2422,"0,0111478117",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-3,Deleterious,1,Damaging,"29,95","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_041,4,106193841,C,A,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln1435Lys/c.4303C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),2669,59,2737,"0,0215564487",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-3,Deleterious,1,Damaging,"28,99","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_004,4,106193841,C,A,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln1435Lys/c.4303C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),3066,52,3124,"0,0166453265",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-3,Deleterious,1,Damaging,"29,95","15,6"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106193841,C,A,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln1435Lys/c.4303C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),19912,347,20330,"0,0170683719",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-3,Deleterious,1,Damaging,"28,75","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106193841,C,A,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln1435Lys/c.4303C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),12511,247,12800,"0,019296875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-3,Deleterious,1,Damaging,"28,85","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_044,4,106193841,C,A,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln1435Lys/c.4303C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),3073,53,3134,"0,0169112955",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-3,Deleterious,1,Damaging,"28,96","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_005,4,106193841,C,A,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln1435Lys/c.4303C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),3128,51,3187,"0,0160025102",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-3,Deleterious,1,Damaging,"29,96","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_045,4,106193841,C,A,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln1435Lys/c.4303C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),12937,262,13250,"0,0197735849",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-3,Deleterious,1,Damaging,"28,77","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_046,4,106193841,C,A,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln1435Lys/c.4303C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),18508,316,18872,"0,0167443832",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-3,Deleterious,1,Damaging,"28,7","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106193841,C,A,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln1435Lys/c.4303C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),22069,406,22540,"0,0180124224",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-3,Deleterious,1,Damaging,"28,77","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_048,4,106193841,C,A,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln1435Lys/c.4303C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),11293,212,11553,"0,0183502121",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-3,Deleterious,1,Damaging,"28,63","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_006,4,106193841,C,A,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln1435Lys/c.4303C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),15874,221,16134,"0,0136977811",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-3,Deleterious,1,Damaging,"29,83","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106193841,C,A,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln1435Lys/c.4303C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),14056,277,14394,"0,0192441295",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-3,Deleterious,1,Damaging,"28,74","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_050,4,106193841,C,A,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln1435Lys/c.4303C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),14018,254,14370,"0,0176757133",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-3,Deleterious,1,Damaging,"28,71","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106193841,C,A,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln1435Lys/c.4303C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),16015,295,16371,"0,0180196689",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-3,Deleterious,1,Damaging,"28,64","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_052,4,106193841,C,A,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln1435Lys/c.4303C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),12460,255,12771,"0,019967113",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-3,Deleterious,1,Damaging,"28,8","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_053,4,106193841,C,A,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln1435Lys/c.4303C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),20299,378,20726,"0,018237962",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-3,Deleterious,1,Damaging,"28,79","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_054,4,106193841,C,A,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln1435Lys/c.4303C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),14549,263,14839,"0,0177235663",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-3,Deleterious,1,Damaging,"28,88","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_007,4,106193841,C,A,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln1435Lys/c.4303C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),28883,389,29321,"0,0132669418",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-3,Deleterious,1,Damaging,"29,83","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_008,4,106193841,C,A,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln1435Lys/c.4303C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),36117,480,36641,"0,0131000791",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-3,Deleterious,1,Damaging,"29,75","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_009,4,106193841,C,A,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln1435Lys/c.4303C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),31759,444,32256,"0,013764881",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-3,Deleterious,1,Damaging,"29,8","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_010,4,106193841,C,A,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln1435Lys/c.4303C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),23949,334,24330,"0,0137279079",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-3,Deleterious,1,Damaging,"29,74","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_011,4,106193841,C,A,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln1435Lys/c.4303C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),24981,320,25347,"0,0126247682",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-3,Deleterious,1,Damaging,"29,77","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_055,4,106193841,C,A,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln1435Lys/c.4303C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),19921,378,20363,"0,0185630801",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-3,Deleterious,1,Damaging,"28,7","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_056,4,106193841,C,A,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln1435Lys/c.4303C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),6686,115,6857,"0,0167711827",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-3,Deleterious,1,Damaging,"28,71","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_057,4,106193841,C,A,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln1435Lys/c.4303C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),19255,372,19676,"0,0189062818",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-3,Deleterious,1,Damaging,"28,77","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_058,4,106193841,C,A,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln1435Lys/c.4303C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),21004,373,21476,"0,017368225",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-3,Deleterious,1,Damaging,"28,73","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_012,4,106193841,C,A,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln1435Lys/c.4303C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),11977,163,12186,"0,0133760053",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-3,Deleterious,1,Damaging,"29,82","15,42"
"low bq, low freq, many artifacts",UPN2_013,4,106193841,C,A,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln1435Lys/c.4303C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),7197,103,7308,"0,0140941434",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-3,Deleterious,1,Damaging,"29,7","14,56"
"inspected, many artifacts",UPN2_041,4,106193850,A,G,missense_variant(MODERATE|MISSENSE|Aaa/Gaa|p.Lys1438Glu/c.4312A>G|2002|TET2|protein_coding|CODING|ENST00000380013|10|G),1308,40,1359,"0,0294334069",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,0,Damaging,"34,53","33,8"
"low bq, low freq, many artifacts, many samples",UPN2_046,4,106193852,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys1438Asn/c.4314A>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),9272,96,9414,"0,0101975781",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,54",Deleterious,0,Damaging,"34,14","23,85"
"low bq, low freq, many artifacts, many samples",UPN2_058,4,106193852,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys1438Asn/c.4314A>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),10490,123,10687,"0,0115093104",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,54",Deleterious,0,Damaging,"33,99","20,1"
"low bq, low freq, many artifacts, many samples",UPN2_057,4,106193853,A,T,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys1439*/c.4315A>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),9644,102,9791,"0,0104177306",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,19","17,06"
"low bq, low freq, many artifacts, many samples",UPN2_045,4,106193854,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys1439Ile/c.4316A>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),6509,68,6614,"0,0102812217",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,85",Neutral,836,Tolerated,"31,95","16,63"
"low bq, low freq, many artifacts, many samples",UPN2_046,4,106193854,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys1439Ile/c.4316A>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),9253,95,9414,"0,0100913533",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,85",Neutral,836,Tolerated,"31,77","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_048,4,106193854,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys1439Ile/c.4316A>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),5669,61,5758,"0,0105939562",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,85",Neutral,836,Tolerated,"32,05","16,16"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106193854,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys1439Ile/c.4316A>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),7041,83,7163,"0,0115873237",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,85",Neutral,836,Tolerated,"31,76","15,34"
"low bq, low freq, many artifacts, many samples",UPN2_050,4,106193854,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys1439Ile/c.4316A>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),7054,76,7164,"0,0106085985",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,85",Neutral,836,Tolerated,"31,86","15,49"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106193854,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys1439Ile/c.4316A>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),8021,97,8163,"0,0118828862",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,85",Neutral,836,Tolerated,"32,06","15,55"
"low bq, low freq, many artifacts, many samples",UPN2_052,4,106193854,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys1439Ile/c.4316A>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),6286,70,6386,"0,0109614782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,85",Neutral,836,Tolerated,"31,64","16,11"
"low bq, low freq, many artifacts, many samples",UPN2_056,4,106193854,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys1439Ile/c.4316A>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),3342,42,3412,"0,0123094959",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,85",Neutral,836,Tolerated,"31,71","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_057,4,106193854,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys1439Ile/c.4316A>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),9635,100,9792,"0,0102124183",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,85",Neutral,836,Tolerated,"31,76","16,32"
"low bq, low freq, many artifacts",UPN2_058,4,106193854,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys1439Ile/c.4316A>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),10532,111,10688,"0,010385479",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,85",Neutral,836,Tolerated,"31,8","16,2"
"low bq, low freq, many artifacts, many samples",UPN2_001,4,106193855,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys1439Asn/c.4317A>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),4741,52,4835,"0,0107549121",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,207,Tolerated,"32,18","17,79"
"low bq, low freq, many artifacts, many samples",UPN2_045,4,106193855,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys1439Asn/c.4317A>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),6493,68,6614,"0,0102812217",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,207,Tolerated,"31,6","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_046,4,106193855,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys1439Asn/c.4317A>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),9238,97,9414,"0,0103038028",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,207,Tolerated,"31,38","16,4"
"low bq, low freq, many artifacts, many samples",UPN2_048,4,106193855,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys1439Asn/c.4317A>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),5633,73,5758,"0,0126780132",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,207,Tolerated,"31,63","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106193855,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys1439Asn/c.4317A>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),7008,83,7164,"0,0115857063",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,207,Tolerated,"31,4","16,84"
"low bq, low freq, many artifacts, many samples",UPN2_050,4,106193855,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys1439Asn/c.4317A>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),7026,74,7164,"0,0103294249",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,207,Tolerated,"31,25","16,31"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106193855,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys1439Asn/c.4317A>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),8006,94,8163,"0,0115153742",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,207,Tolerated,"31,59","15,9"
"low bq, low freq, many artifacts, many samples",UPN2_052,4,106193855,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys1439Asn/c.4317A>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),6257,71,6386,"0,0111180708",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,207,Tolerated,"31,28","15,77"
"low bq, low freq, many artifacts, many samples",UPN2_053,4,106193855,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys1439Asn/c.4317A>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),10125,128,10345,"0,0123731271",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,207,Tolerated,"31,43","16,86"
"low bq, low freq, many artifacts, many samples",UPN2_055,4,106193855,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys1439Asn/c.4317A>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),9933,103,10152,"0,0101457841",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,207,Tolerated,"31,42","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_057,4,106193855,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys1439Asn/c.4317A>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),9589,111,9792,"0,0113357843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,207,Tolerated,"31,43","16,31"
"low bq, low freq, many artifacts",UPN2_058,4,106193855,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys1439Asn/c.4317A>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),10474,120,10689,"0,0112264945",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,207,Tolerated,"31,46","15,37"
"low bq, low freq, many artifacts",UPN2_041,4,106193859,A,T,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser1441Cys/c.4321A>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),1336,22,1360,"0,0161764706",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,6,Damaging,"34,01","23,32"
"inspected, many artifacts",UPN2_044,4,106193892,C,T,stop_gained(HIGH|NONSENSE|Cga/Tga|p.Arg1452*/c.4354C>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),1504,51,1561,"0,0326713645",0,0,0,0,1,0,0,1,2,NO,NO,COSM41706,haematopoietic_and_lymphoid_tissue,12,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,97","31,43"
"low freq, many artifacts",UPN2_044,4,106193904,AT,A,frameshift_variant(HIGH||atg/|p.Met1456fs/c.4367delT|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),4413,60,4505,"0,013318535",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,78",NA
"inspected, connected to del, strandbias",UPN2_071,4,106193929,G,A,missense_variant(MODERATE|MISSENSE|tGc/tAc|p.Cys1464Tyr/c.4391G>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),5354,825,6194,"0,133193413",1,1,0,0,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,32",Deleterious,0,Damaging,"34,76","33,87"
"low freq, many artifacts",UPN2_063,4,106193931,C,T,stop_gained(HIGH|NONSENSE|Cga/Tga|p.Arg1465*/c.4393C>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),10588,209,10840,"0,0192804428",0,0,0,0,1,1,0,1,3,NO,NO,COSM42016,haematopoietic_and_lymphoid_tissue,26,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,72","35,15"
"low freq, many artifacts",UPN2_041,4,106193950,C,T,missense_variant(MODERATE|MISSENSE|gCc/gTc|p.Ala1471Val/c.4412C>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),2318,37,2364,"0,0156514382",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,"0,005",Damaging,"33,1","30,57"
"low freq, many artifacts, many samples",UPN2_042,4,106193971,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1478Arg/c.4433A>G|2002|TET2|protein_coding|CODING|ENST00000380013|10|G),16072,163,16263,"0,010022751",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,2",Neutral,79,Tolerated,"34,38","34,19"
"many samples, low freq, many artifacts",UPN2_043,4,106193971,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1478Arg/c.4433A>G|2002|TET2|protein_coding|CODING|ENST00000380013|10|G),10609,111,10731,"0,0103438636",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,2",Neutral,"0,079",Tolerated,"34,34","33,24"
"many samples, low freq, many artifacts",UPN2_056,4,106193971,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1478Arg/c.4433A>G|2002|TET2|protein_coding|CODING|ENST00000380013|10|G),4274,45,4330,"0,0103926097",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,2",Neutral,"0,079",Tolerated,"34,35","34,91"
"many samples, low freq, many artifacts",UPN2_090,4,106193971,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1478Arg/c.4433A>G|2002|TET2|protein_coding|CODING|ENST00000380013|10|G),4533,50,4584,"0,0109075044",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,2",Neutral,"0,079",Tolerated,"34,82","33,4"
"many samples, low freq, many artifacts",UPN2_058,4,106193971,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1478Arg/c.4433A>G|2002|TET2|protein_coding|CODING|ENST00000380013|10|G),13898,141,14049,"0,0100363015",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,2",Neutral,"0,079",Tolerated,"34,37","33,3"
"many samples, low freq, many artifacts",UPN2_063,4,106193971,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1478Arg/c.4433A>G|2002|TET2|protein_coding|CODING|ENST00000380013|10|G),5678,59,5759,"0,0102448342",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,2",Neutral,"0,079",Tolerated,"33,39","32,73"
"low freq, many artifacts, many samples",UPN2_080,4,106193971,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1478Arg/c.4433A>G|2002|TET2|protein_coding|CODING|ENST00000380013|10|G),5164,53,5222,"0,0101493681",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,2",Neutral,79,Tolerated,"33,35","33,34"
"many samples, low freq, many artifacts",UPN2_083,4,106193971,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1478Arg/c.4433A>G|2002|TET2|protein_coding|CODING|ENST00000380013|10|G),8188,83,8283,"0,010020524",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,2",Neutral,"0,079",Tolerated,"33,27","33,41"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106193976,T,A,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser1480Thr/c.4438T>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),16039,164,16256,"0,0100885827",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,28,Damaging,"34,13","17,69"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106193976,T,A,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser1480Thr/c.4438T>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),10581,113,10727,"0,0105341661",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,28,Damaging,"34,08","19,27"
"low bq, low freq, many artifacts, many samples",UPN2_050,4,106193976,T,A,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser1480Thr/c.4438T>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),11939,131,12126,"0,0108032327",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,28,Damaging,"34,09","18,25"
"low bq, low freq, many artifacts",UPN2_053,4,106193976,T,A,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser1480Thr/c.4438T>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),15887,172,16122,"0,0106686515",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,28,Damaging,"34,12","17,42"
"low freq, many artifacts",UPN2_071,4,106193976,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1480Pro/c.4438T>C|2002|TET2|protein_coding|CODING|ENST00000380013|10|C),3335,34,3393,"0,0100206307",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,"0,01",Damaging,"34,26","33,41"
"inspected, many artifacts",UPN2_041,4,106193982,C,A,missense_variant(MODERATE|MISSENSE|Ctg/Atg|p.Leu1482Met/c.4444C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),1002,22,1024,"0,021484375",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,067",Tolerated,"34,09","31,82"
"low bq, low freq, many artifacts",UPN2_056,4,106193983,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu1482Gln/c.4445T>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),4253,53,4328,"0,012245841",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,72",Deleterious,44,Damaging,"33,98","23,49"
"low bq, low freq, many artifacts, many samples",UPN2_070,4,106193988,A,C,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn1484His/c.4450A>C|2002|TET2|protein_coding|CODING|ENST00000380013|10|C),4851,60,4938,"0,0121506683",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,7",Neutral,1,Damaging,"29,08","15,53"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106193988,A,C,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn1484His/c.4450A>C|2002|TET2|protein_coding|CODING|ENST00000380013|10|C),5032,53,5100,"0,0103921569",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,7",Neutral,1,Damaging,"29,31",14
"low bq, low freq, many artifacts, many samples",UPN2_048,4,106194005,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1489Lys/c.4467T>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),6761,73,6855,"0,0106491612",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,71,Tolerated,"33,37","16,1"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106194005,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1489Lys/c.4467T>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),10631,121,10814,"0,0111891992",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,71,Tolerated,"33,43","20,47"
"low bq, low freq, many artifacts, many samples",UPN2_052,4,106194005,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1489Lys/c.4467T>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),9700,115,9872,"0,0116491086",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,71,Tolerated,"33,32","19,03"
"low bq, low freq, many artifacts, many samples",UPN2_056,4,106194005,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1489Lys/c.4467T>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),4272,46,4328,"0,0106284658",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,71,Tolerated,"33,44","15,59"
"low bq, low freq, many artifacts",UPN2_075,4,106194005,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1489Lys/c.4467T>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),6576,67,6672,"0,0100419664",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,71,Tolerated,"33,4","16,31"
"low freq, many artifacts",UPN2_044,4,106194010,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1491Arg/c.4472A>G|2002|TET2|protein_coding|CODING|ENST00000380013|10|G),2904,35,2944,"0,011888587",0,0,0,0,1,0,0,1,2,NO,NO,COSM220690,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-2,45",Neutral,"0,108",Tolerated,"33,27","33,06"
"low freq, many artifacts",UPN2_051,4,106194016,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1493Arg/c.4478A>G|2002|TET2|protein_coding|CODING|ENST00000380013|10|G),22033,246,22341,"0,0110111454",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,18",Neutral,"0,005",Damaging,"32,85","28,1"
"low freq, many artifacts",UPN2_055,4,106194016,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1493Arg/c.4478A>G|2002|TET2|protein_coding|CODING|ENST00000380013|10|G),33158,336,33567,"0,0100098311",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,18",Neutral,5,Damaging,"32,81","28,66"
"low freq, many artifacts",UPN2_071,4,106194016,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1493Arg/c.4478A>G|2002|TET2|protein_coding|CODING|ENST00000380013|10|G),6718,86,6828,"0,0125951963",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,18",Neutral,"0,005",Damaging,"31,99","29,51"
"low freq, many artifacts",UPN2_111,4,106194016,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1493Arg/c.4478A>G|2002|TET2|protein_coding|CODING|ENST00000380013|10|G),17629,182,17837,"0,0102035096",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,18",Neutral,"0,005",Damaging,"33,21","29,03"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106194018,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser1494Thr/c.4480T>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),32174,342,32661,"0,0104712042",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,6,Damaging,"32,01","20,07"
"low bq, low freq, many artifacts, many samples",UPN2_044,4,106194018,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser1494Thr/c.4480T>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),5812,75,5920,"0,0126689189",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,6,Damaging,"31,99","16,99"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106194018,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser1494Thr/c.4480T>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),21981,262,22343,"0,0117262677",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,6,Damaging,"32,03","19,97"
"low bq, low freq, many artifacts, many samples",UPN2_055,4,106194018,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser1494Thr/c.4480T>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),33072,346,33566,"0,0103080498",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,6,Damaging,"32,05","18,3"
"low bq, low freq, many artifacts",UPN2_057,4,106194018,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser1494Thr/c.4480T>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),29001,296,29387,"0,010072481",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,6,Damaging,32,"18,51"
"low bq, low freq, many artifacts, many samples",UPN2_059,4,106194021,G,T,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala1495Ser/c.4483G>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),18973,230,19260,"0,0119418484",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,19",Neutral,"0,39",Tolerated,"28,42","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_061,4,106194021,G,T,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala1495Ser/c.4483G>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),12471,134,12628,"0,0106113399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,19",Neutral,"0,39",Tolerated,"28,5","15,73"
"low bq, low freq, many artifacts, many samples",UPN2_062,4,106194021,G,T,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala1495Ser/c.4483G>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),9027,94,9154,"0,010268735",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,19",Neutral,"0,39",Tolerated,"28,53","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_065,4,106194021,G,T,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala1495Ser/c.4483G>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),14863,173,15095,"0,0114607486",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,19",Neutral,"0,39",Tolerated,"28,34","15,71"
"low bq, low freq, many artifacts, many samples",UPN2_066,4,106194021,G,T,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala1495Ser/c.4483G>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),23931,264,24279,"0,0108735945",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,19",Neutral,"0,39",Tolerated,"28,34","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_067,4,106194021,G,T,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala1495Ser/c.4483G>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),29927,321,30379,"0,0105665098",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,19",Neutral,"0,39",Tolerated,"28,36","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_069,4,106194021,G,T,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala1495Ser/c.4483G>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),16155,172,16391,"0,0104935635",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,19",Neutral,"0,39",Tolerated,"28,51","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106194021,G,T,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala1495Ser/c.4483G>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),8130,98,8260,"0,0118644068",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,19",Neutral,"0,39",Tolerated,"28,31","15,9"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106194021,G,T,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala1495Ser/c.4483G>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),10076,125,10235,"0,0122129946",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,19",Neutral,"0,39",Tolerated,"28,28","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_074,4,106194021,G,T,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala1495Ser/c.4483G>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),11685,136,11857,"0,0114700177",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,19",Neutral,"0,39",Tolerated,"28,34","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_075,4,106194021,G,T,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala1495Ser/c.4483G>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),13206,138,13413,"0,0102885261",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,19",Neutral,"0,39",Tolerated,"28,3","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106194021,G,T,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala1495Ser/c.4483G>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),14269,156,14493,"0,010763817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,19",Neutral,"0,39",Tolerated,"28,35","16,08"
"low bq, low freq, many artifacts, many samples",UPN2_082,4,106194021,G,T,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala1495Ser/c.4483G>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),23758,251,24090,"0,0104192611",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,19",Neutral,"0,39",Tolerated,"28,38","15,6"
"low bq, low freq, many artifacts",UPN2_087,4,106194021,G,T,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala1495Ser/c.4483G>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),22013,235,22344,"0,0105173648",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,19",Neutral,"0,39",Tolerated,"28,4","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_061,4,106194022,C,A,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala1495Asp/c.4484C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),12445,135,12631,"0,0106879899",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,18,Damaging,"29,54","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_062,4,106194022,C,A,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala1495Asp/c.4484C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),9020,106,9152,"0,0115821678",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,18,Damaging,"29,47","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_063,4,106194022,C,A,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala1495Asp/c.4484C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),11355,125,11563,"0,0108103433",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,18,Damaging,"29,53","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_064,4,106194022,C,A,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala1495Asp/c.4484C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),14244,152,14454,"0,0105161201",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,18,Damaging,"29,46","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_066,4,106194022,C,A,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala1495Asp/c.4484C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),23893,277,24281,"0,0114080969",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,18,Damaging,"29,29","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_067,4,106194022,C,A,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala1495Asp/c.4484C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),29889,341,30380,"0,0112244898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,18,Damaging,"29,32","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_071,4,106194022,C,A,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala1495Asp/c.4484C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),6709,70,6823,"0,0102594167",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,18,Damaging,"29,46","19,91"
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106194022,C,A,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala1495Asp/c.4484C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),8144,83,8261,"0,0100472098",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,18,Damaging,"29,4","16,02"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106194022,C,A,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala1495Asp/c.4484C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),10082,106,10236,"0,0103556077",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,18,Damaging,"29,36","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_074,4,106194022,C,A,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala1495Asp/c.4484C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),11659,127,11857,"0,0107109724",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,18,Damaging,"29,42","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_076,4,106194022,C,A,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala1495Asp/c.4484C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),12634,130,12818,"0,0101419878",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,18,Damaging,"29,51","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_079,4,106194022,C,A,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala1495Asp/c.4484C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),8207,102,8351,"0,0122141061",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,18,Damaging,"29,41","15,79"
"low bq, low freq, many artifacts, many samples",UPN2_080,4,106194022,C,A,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala1495Asp/c.4484C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),10318,116,10482,"0,0110665903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,18,Damaging,"29,48","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106194022,C,A,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala1495Asp/c.4484C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),14270,160,14498,"0,011036005",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,18,Damaging,"29,41","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_083,4,106194022,C,A,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala1495Asp/c.4484C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),16392,170,16624,"0,010226179",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,18,Damaging,"29,62","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_085,4,106194022,C,A,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala1495Asp/c.4484C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),19264,202,19548,"0,010333538",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,18,Damaging,"29,45","14,94"
"low bq, low freq, many artifacts",UPN2_086,4,106194022,C,A,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala1495Asp/c.4484C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),17797,184,18047,"0,0101956004",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,18,Damaging,"29,55","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_041,4,106194024,C,A,missense_variant(MODERATE|MISSENSE|Cca/Aca|p.Pro1496Thr/c.4486C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),2029,23,2056,"0,0111867704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,325,Tolerated,"29,68","15,74"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106194024,C,A,missense_variant(MODERATE|MISSENSE|Cca/Aca|p.Pro1496Thr/c.4486C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),32238,348,32663,"0,0106542571",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,325,Tolerated,"29,77","16,93"
"low bq, low freq, many artifacts, many samples",UPN2_056,4,106194024,C,A,missense_variant(MODERATE|MISSENSE|Cca/Aca|p.Pro1496Thr/c.4486C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),8602,89,8704,"0,0102251838",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,325,Tolerated,"29,88","15,56"
"low bq, low freq, many artifacts, many samples",UPN2_059,4,106194024,C,A,missense_variant(MODERATE|MISSENSE|Cca/Aca|p.Pro1496Thr/c.4486C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),18929,259,19270,"0,0134405812",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,325,Tolerated,"28,58","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_060,4,106194024,C,A,missense_variant(MODERATE|MISSENSE|Cca/Aca|p.Pro1496Thr/c.4486C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),11547,140,11749,"0,0119159077",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,325,Tolerated,"28,52","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_061,4,106194024,C,A,missense_variant(MODERATE|MISSENSE|Cca/Aca|p.Pro1496Thr/c.4486C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),12424,159,12631,"0,012588077",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,325,Tolerated,"28,47",16
"low bq, low freq, many artifacts, many samples",UPN2_062,4,106194024,C,A,missense_variant(MODERATE|MISSENSE|Cca/Aca|p.Pro1496Thr/c.4486C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),8997,115,9153,"0,0125641866",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,325,Tolerated,"28,5","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_063,4,106194024,C,A,missense_variant(MODERATE|MISSENSE|Cca/Aca|p.Pro1496Thr/c.4486C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),11336,158,11556,"0,0136725511",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,325,Tolerated,"28,67","16,39"
"low bq, low freq, many artifacts, many samples",UPN2_064,4,106194024,C,A,missense_variant(MODERATE|MISSENSE|Cca/Aca|p.Pro1496Thr/c.4486C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),14201,183,14454,"0,0126608551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,325,Tolerated,"28,48","15,73"
"low bq, low freq, many artifacts, many samples",UPN2_065,4,106194024,C,A,missense_variant(MODERATE|MISSENSE|Cca/Aca|p.Pro1496Thr/c.4486C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),14845,178,15095,"0,0117919841",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,325,Tolerated,"28,45","15,34"
"low bq, low freq, many artifacts, many samples",UPN2_066,4,106194024,C,A,missense_variant(MODERATE|MISSENSE|Cca/Aca|p.Pro1496Thr/c.4486C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),23867,289,24277,"0,0119042715",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,325,Tolerated,"28,46","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_067,4,106194024,C,A,missense_variant(MODERATE|MISSENSE|Cca/Aca|p.Pro1496Thr/c.4486C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),29846,420,30392,"0,0138194262",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,325,Tolerated,"28,35","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_068,4,106194024,C,A,missense_variant(MODERATE|MISSENSE|Cca/Aca|p.Pro1496Thr/c.4486C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),17001,192,17261,"0,0111233416",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,325,Tolerated,"28,5","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_069,4,106194024,C,A,missense_variant(MODERATE|MISSENSE|Cca/Aca|p.Pro1496Thr/c.4486C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),16126,207,16400,"0,0126219512",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,325,Tolerated,"28,49","15,62"
"low bq, low freq, many artifacts, many samples",UPN2_070,4,106194024,C,A,missense_variant(MODERATE|MISSENSE|Cca/Aca|p.Pro1496Thr/c.4486C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),9752,120,9914,"0,0121040952",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,325,Tolerated,"28,56","15,69"
"low bq, low freq, many artifacts, many samples",UPN2_071,4,106194024,C,A,missense_variant(MODERATE|MISSENSE|Cca/Aca|p.Pro1496Thr/c.4486C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),6726,70,6821,"0,0102624249",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,325,Tolerated,"28,43","15,71"
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106194024,C,A,missense_variant(MODERATE|MISSENSE|Cca/Aca|p.Pro1496Thr/c.4486C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),8118,108,8261,"0,0130734778",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,325,Tolerated,"28,5","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106194024,C,A,missense_variant(MODERATE|MISSENSE|Cca/Aca|p.Pro1496Thr/c.4486C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),10069,123,10234,"0,012018761",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,325,Tolerated,"28,38","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_074,4,106194024,C,A,missense_variant(MODERATE|MISSENSE|Cca/Aca|p.Pro1496Thr/c.4486C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),11661,146,11860,"0,0123102867",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,325,Tolerated,"28,51","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_075,4,106194024,C,A,missense_variant(MODERATE|MISSENSE|Cca/Aca|p.Pro1496Thr/c.4486C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),13205,145,13415,"0,0108087961",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,325,Tolerated,"28,46","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_076,4,106194024,C,A,missense_variant(MODERATE|MISSENSE|Cca/Aca|p.Pro1496Thr/c.4486C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),12609,151,12816,"0,0117821473",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,325,Tolerated,"28,43","15,39"
"low bq, low freq, many artifacts, many samples",UPN2_077,4,106194024,C,A,missense_variant(MODERATE|MISSENSE|Cca/Aca|p.Pro1496Thr/c.4486C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),15455,186,15707,"0,011841854",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,325,Tolerated,"28,48","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_078,4,106194024,C,A,missense_variant(MODERATE|MISSENSE|Cca/Aca|p.Pro1496Thr/c.4486C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),10862,119,11035,"0,0107838695",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,325,Tolerated,"28,55","14,11"
"low bq, low freq, many artifacts, many samples",UPN2_079,4,106194024,C,A,missense_variant(MODERATE|MISSENSE|Cca/Aca|p.Pro1496Thr/c.4486C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),8228,86,8350,"0,0102994012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,325,Tolerated,"28,52","15,58"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106194024,C,A,missense_variant(MODERATE|MISSENSE|Cca/Aca|p.Pro1496Thr/c.4486C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),14247,200,14499,"0,0137940548",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,325,Tolerated,"28,51","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_082,4,106194024,C,A,missense_variant(MODERATE|MISSENSE|Cca/Aca|p.Pro1496Thr/c.4486C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),23659,312,24095,"0,0129487446",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,325,Tolerated,"28,55","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_083,4,106194024,C,A,missense_variant(MODERATE|MISSENSE|Cca/Aca|p.Pro1496Thr/c.4486C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),16367,190,16624,"0,0114292589",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,325,Tolerated,"28,53","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_084,4,106194024,C,A,missense_variant(MODERATE|MISSENSE|Cca/Aca|p.Pro1496Thr/c.4486C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),17710,212,17981,"0,011790223",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,325,Tolerated,"28,52","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_085,4,106194024,C,A,missense_variant(MODERATE|MISSENSE|Cca/Aca|p.Pro1496Thr/c.4486C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),19217,253,19549,"0,0129418385",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,325,Tolerated,"28,44","15,34"
"low bq, low freq, many artifacts, many samples",UPN2_086,4,106194024,C,A,missense_variant(MODERATE|MISSENSE|Cca/Aca|p.Pro1496Thr/c.4486C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),17760,206,18049,"0,0114133747",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,325,Tolerated,"28,5","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_087,4,106194024,C,A,missense_variant(MODERATE|MISSENSE|Cca/Aca|p.Pro1496Thr/c.4486C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),21976,242,22345,"0,0108301633",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,325,Tolerated,"28,44","14,76"
"low bq, low freq, many artifacts",UPN2_088,4,106194024,C,A,missense_variant(MODERATE|MISSENSE|Cca/Aca|p.Pro1496Thr/c.4486C>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),14412,175,14649,"0,0119462079",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,325,Tolerated,"28,42","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_041,4,106194027,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser1497Thr/c.4489T>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),2023,23,2056,"0,0111867704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,203,Tolerated,32,"15,13"
"low bq, low freq, many artifacts, many samples",UPN2_044,4,106194027,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser1497Thr/c.4489T>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),5818,75,5927,"0,0126539565",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,203,Tolerated,"32,24","20,21"
"low bq, low freq, many artifacts, many samples",UPN2_054,4,106194027,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser1497Thr/c.4489T>A|2002|TET2|protein_coding|CODING|ENST00000380013|10|A),18975,203,19267,"0,0105361499",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,203,Tolerated,"32,15","19,15"
"low bq, low freq, many artifacts, many samples",UPN2_004,4,106194031,G,T,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg1498Leu/c.4493G>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),1635,20,1661,"0,0120409392",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,2",Deleterious,39,Damaging,"33,22","25,7"
"inspected, many artifacts",UPN2_041,4,106194039,C,G,missense_variant(MODERATE|MISSENSE|Caa/Gaa|p.Gln1501Glu/c.4501C>G|2002|TET2|protein_coding|CODING|ENST00000380013|10|G),1990,55,2055,"0,0267639903",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,57",Neutral,"0,036",Damaging,"32,56","31,45"
"low freq, many artifacts",UPN2_041,4,106194040,A,G,missense_variant(MODERATE|MISSENSE|cAa/cGa|p.Gln1501Arg/c.4502A>G|2002|TET2|protein_coding|CODING|ENST00000380013|10|G),2021,28,2055,"0,0136253041",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,"0,079",Tolerated,"33,07","29,61"
"low bq, low freq, many artifacts, many samples",UPN2_059,4,106194051,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1505Ser/c.4513G>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),9631,98,9753,"0,0100481903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,"-0,27",Neutral,"0,26",Tolerated,"30,48","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_060,4,106194051,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1505Ser/c.4513G>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),5870,61,5949,"0,0102538242",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,"-0,27",Neutral,"0,26",Tolerated,"30,49","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_066,4,106194051,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1505Ser/c.4513G>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),12115,125,12281,"0,0101783242",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,"-0,27",Neutral,"0,26",Tolerated,"30,42","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_067,4,106194051,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1505Ser/c.4513G>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),15177,170,15382,"0,0110518788",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,"-0,27",Neutral,"0,26",Tolerated,"30,33","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106194051,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1505Ser/c.4513G>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),7225,77,7336,"0,0104961832",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,"-0,27",Neutral,"0,26",Tolerated,"30,5","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_084,4,106194051,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1505Ser/c.4513G>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),8975,93,9102,"0,0102175346",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,"-0,27",Neutral,"0,26",Tolerated,"30,62","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_086,4,106194051,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1505Ser/c.4513G>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),9023,92,9133,"0,0100733603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,"-0,27",Neutral,"0,26",Tolerated,"30,56","15,15"
"low bq, low freq, many artifacts",UPN2_088,4,106194051,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1505Ser/c.4513G>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),7324,75,7414,"0,0101159968",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,"-0,27",Neutral,"0,26",Tolerated,"30,4","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_061,4,106194060,G,T,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala1508Ser/c.4522G>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),6323,68,6401,"0,0106233401",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,202,Tolerated,"30,35","16,03"
"low bq, low freq, many artifacts, many samples",UPN2_067,4,106194060,G,T,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala1508Ser/c.4522G>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),15193,171,15389,"0,0111118331",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,202,Tolerated,"30,07","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106194060,G,T,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala1508Ser/c.4522G>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),5116,63,5182,"0,0121574682",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,202,Tolerated,"30,16","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_074,4,106194060,G,T,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala1508Ser/c.4522G>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),5911,69,5988,"0,0115230461",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,202,Tolerated,"30,2","15,67"
"low bq, low freq, many artifacts",UPN2_088,4,106194060,G,T,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala1508Ser/c.4522G>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),7319,84,7419,"0,0113222806",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,202,Tolerated,"30,14","14,79"
"low freq, many artifacts",UPN2_044,4,106194070,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1511Ser/c.4532T>C|2002|TET2|protein_coding|CODING|ENST00000380013|10|C),2941,50,2996,"0,0166889186",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,"0,016",Damaging,"34,5","31,26"
"low bq, low freq, many artifacts, many samples",UPN2_064,4,106194071,G,T,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu1511Phe/c.4533G>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),7216,83,7313,"0,0113496513",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,3,Damaging,"30,53","18,88"
"low bq, low freq, many artifacts, many samples",UPN2_074,4,106194071,G,T,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu1511Phe/c.4533G>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),5914,63,5988,"0,0105210421",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,3,Damaging,"30,58","16,46"
"low bq, low freq, many artifacts, many samples",UPN2_083,4,106194071,G,T,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu1511Phe/c.4533G>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),8309,87,8421,"0,0103313146",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,3,Damaging,"30,8","15,94"
"low bq, low freq, many artifacts, many samples",UPN2_059,4,106194072,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1512Ser/c.4534G>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),9684,99,9798,"0,0101041029",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,67",Neutral,48,Damaging,"31,26","15,92"
"low bq, low freq, many artifacts, many samples",UPN2_061,4,106194072,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1512Ser/c.4534G>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),6330,65,6406,"0,0101467374",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,67",Neutral,48,Damaging,"31,49","17,8"
"low bq, low freq, many artifacts, many samples",UPN2_062,4,106194072,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1512Ser/c.4534G>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),4581,49,4638,"0,0105648987",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,67",Neutral,48,Damaging,"31,55","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_067,4,106194072,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1512Ser/c.4534G>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),15222,161,15402,"0,0104531879",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,67",Neutral,48,Damaging,"31,23","16,43"
"low bq, low freq, many artifacts, many samples",UPN2_074,4,106194072,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1512Ser/c.4534G>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),5918,63,5989,"0,0105192854",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,67",Neutral,48,Damaging,"31,41","15,54"
"low bq, low freq, many artifacts, many samples",UPN2_075,4,106194072,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1512Ser/c.4534G>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),6716,73,6808,"0,0107226792",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,67",Neutral,48,Damaging,"31,28","15,66"
"low bq, low freq, many artifacts, many samples",UPN2_076,4,106194072,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1512Ser/c.4534G>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),6412,65,6485,"0,0100231303",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,67",Neutral,48,Damaging,"31,59","18,66"
"low bq, low freq, many artifacts",UPN2_081,4,106194072,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala1512Ser/c.4534G>T|2002|TET2|protein_coding|CODING|ENST00000380013|10|T),7255,81,7345,"0,0110279101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,67",Neutral,48,Damaging,"31,36","16,01"
"low freq, many artifacts",UPN2_041,4,106196204,G,T,(TET2|ENSG00000168769|11|0,6881,88,6997,"0,0125768186",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,,,,,"33,07","29,22"
"low freq, many artifacts",UPN2_044,4,106196232,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1522Thr/c.4565T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2741,52,2803,"0,0185515519",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,"0,612",Tolerated,"34,68","34,56"
"many samples, low bq, low freq",UPN2_001,4,106196235,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln1523Leu/c.4568A>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),5057,57,5131,"0,0111089456",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,4",Neutral,"0,032",Damaging,"34,92",30
"many samples, low bq, low freq",UPN2_016,4,106196235,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln1523Leu/c.4568A>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),7303,83,7414,"0,0111950364",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,4",Neutral,"0,032",Damaging,35,"31,04"
"many samples, low bq, low freq",UPN2_002,4,106196235,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln1523Leu/c.4568A>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),6725,89,6849,"0,0129945978",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,4",Neutral,"0,032",Damaging,"34,9","29,61"
"many samples, low bq, low freq",UPN2_041,4,106196235,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln1523Leu/c.4568A>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),4015,47,4085,"0,011505508",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,4",Neutral,"0,032",Damaging,"34,57","26,74"
"many samples, low bq, low freq",UPN2_005,4,106196235,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln1523Leu/c.4568A>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),1870,43,1921,"0,0223841749",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,4",Neutral,"0,032",Damaging,"34,78","29,26"
"many samples, low bq, low freq",UPN2_008,4,106196235,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln1523Leu/c.4568A>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),23791,343,24234,"0,0141536684",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,4",Neutral,"0,032",Damaging,"34,83","30,37"
"many samples, low bq, low freq",UPN2_010,4,106196235,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln1523Leu/c.4568A>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),9806,147,9986,"0,0147206089",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,4",Neutral,"0,032",Damaging,"34,85","29,21"
"many samples, low bq, low freq",UPN2_011,4,106196235,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln1523Leu/c.4568A>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),12446,219,12724,"0,0172115687",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,4",Neutral,"0,032",Damaging,"34,86","30,09"
"low freq, many artifacts",UPN2_056,4,106196235,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln1523Leu/c.4568A>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),1522,22,1552,"0,0141752577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,4",Neutral,32,Damaging,"34,18","32,73"
"many samples, low bq, low freq",UPN2_090,4,106196235,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln1523Leu/c.4568A>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),6934,416,7388,"0,0563075257",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,4",Neutral,"0,032",Damaging,"35,14","31,79"
"many samples, low bq, low freq",UPN2_012,4,106196235,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln1523Leu/c.4568A>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),6322,147,6503,"0,0226049516",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,4",Neutral,"0,032",Damaging,"34,89","30,96"
"many samples, low bq, low freq",UPN2_013,4,106196235,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln1523Leu/c.4568A>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),3622,190,3825,"0,0496732026",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,4",Neutral,"0,032",Damaging,"34,86","31,03"
"low bq, low freq, many artifacts",UPN2_048,4,106196240,T,A,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser1525Thr/c.4573T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1814,20,1837,"0,0108873163",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,485,Tolerated,"34,83","22,7"
"low freq, many artifacts",UPN2_041,4,106196244,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln1526Leu/c.4577A>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),4036,52,4102,"0,0126767431",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,"0,07",Tolerated,"34,46","30,42"
"low freq, many artifacts",UPN2_005,4,106196245,G,GCCCA,frameshift_variant(HIGH||cag/cCCACag|p.Gln1527fs/c.4579_4580insCCAC|2002|TET2|protein_coding|CODING|ENST00000380013|11|GCCCA|INFO_REALIGN_3_PRIME),1922,34,1928,"0,0176348548",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,85",NA
"low freq, many artifacts",UPN2_011,4,106196245,G,GCCCA,frameshift_variant(HIGH||cag/cCCACag|p.Gln1527fs/c.4579_4580insCCAC|2002|TET2|protein_coding|CODING|ENST00000380013|11|GCCCA|INFO_REALIGN_3_PRIME),12696,176,12741,"0,0138136724",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,35,NA
"inspected, bad alignment",UPN2_090,4,106196245,G,GCCCA,frameshift_variant(HIGH||cag/cCCACag|p.Gln1527fs/c.4579_4580insCCAC|2002|TET2|protein_coding|CODING|ENST00000380013|11|GCCCA|INFO_REALIGN_3_PRIME),7368,399,7395,"0,0539553753",0,1,0,1,0,1,0,1,4,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,91",NA
"low freq, many artifacts",UPN2_012,4,106196245,G,GCCCA,frameshift_variant(HIGH||cag/cCCACag|p.Gln1527fs/c.4579_4580insCCAC|2002|TET2|protein_coding|CODING|ENST00000380013|11|GCCCA|INFO_REALIGN_3_PRIME),6513,100,6536,"0,0152998776",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,93",NA
"inspected, bad alignment",UPN2_013,4,106196245,G,GCCCA,frameshift_variant(HIGH||cag/cCCACag|p.Gln1527fs/c.4579_4580insCCAC|2002|TET2|protein_coding|CODING|ENST00000380013|11|GCCCA|INFO_REALIGN_3_PRIME),3829,160,3842,"0,0416449766",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,95",NA
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106196259,T,A,missense_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu1531Gln/c.4592T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),10845,133,11019,"0,0120700608",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,63",Neutral,108,Tolerated,"33,86","18,28"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106196259,T,A,missense_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu1531Gln/c.4592T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),11418,164,11630,"0,0141014617",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,63",Neutral,108,Tolerated,"33,92","18,52"
"low bq, low freq, many artifacts, many samples",UPN2_048,4,106196259,T,A,missense_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu1531Gln/c.4592T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1799,34,1842,"0,0184581976",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,63",Neutral,108,Tolerated,"33,71","17,94"
"low freq, many artifacts",UPN2_044,4,106196265,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1533Arg/c.4598A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),2705,36,2754,"0,0130718954",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,5",Neutral,"0,704",Tolerated,"33,76","34,11"
"low freq, many artifacts",UPN2_048,4,106196280,C,T,missense_variant(MODERATE|MISSENSE|cCc/cTc|p.Pro1538Leu/c.4613C>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),1811,24,1841,"0,0130363933",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,82",Neutral,"0,03",Damaging,"34,36","34,38"
"low freq, many artifacts",UPN2_001,4,106196281,CCAG,C,inframe_deletion(MODERATE||cag/|p.Gln1542del/c.4624_4626delCAG|2002|TET2|protein_coding|CODING|ENST00000380013|11|C|INFO_REALIGN_3_PRIME),5104,53,5178,"0,0102356122",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,NA,NA,"34,71",NA
"low freq, many artifacts",UPN2_005,4,106196281,CCAG,C,inframe_deletion(MODERATE||cag/|p.Gln1542del/c.4624_4626delCAG|2002|TET2|protein_coding|CODING|ENST00000380013|11|C|INFO_REALIGN_3_PRIME),1947,22,1974,"0,0111448835",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,NA,NA,"34,86",NA
"low freq, many artifacts",UPN2_011,4,106196281,CCAG,C,inframe_deletion(MODERATE||cag/|p.Gln1542del/c.4624_4626delCAG|2002|TET2|protein_coding|CODING|ENST00000380013|11|C|INFO_REALIGN_3_PRIME),12781,133,12934,"0,0102829751",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,NA,NA,"34,79",NA
"low freq, many artifacts, many samples",UPN2_005,4,106196283,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1539Pro/c.4616A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1910,26,1952,"0,0133196721",0,0,0,0,0,0,0,1,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,256,Tolerated,"33,89","32,58"
"low freq, many artifacts, many samples",UPN2_044,4,106196288,CA,C,frameshift_variant(HIGH||cag/|p.Gln1541fs/c.4622delA|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2751,39,2808,"0,0138888889",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,05",NA
"low freq, many artifacts, many samples",UPN2_093,4,106196290,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1541His/c.4623G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4122,45,4174,"0,0107810254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,02",Neutral,141,Tolerated,"35,09","33,69"
"low freq, many artifacts, low bq",UPN2_041,4,106196296,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg1543Ser/c.4629A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4045,47,4115,"0,0114216282",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,"0,04",Damaging,"33,58","26,53"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106196296,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg1543Ser/c.4629A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),10861,199,11123,"0,0178908568",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,"0,04",Damaging,"28,1","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106196296,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg1543Ser/c.4629A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),12914,136,13124,"0,0103626943",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,"0,04",Damaging,"31,31","15,52"
"low bq, low freq, many artifacts, many samples",UPN2_044,4,106196296,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg1543Ser/c.4629A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2743,38,2804,"0,0135520685",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,"0,04",Damaging,"30,7","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_045,4,106196296,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg1543Ser/c.4629A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),16991,198,17288,"0,011453031",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,"0,04",Damaging,"31,38","16,26"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106196296,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg1543Ser/c.4629A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),11395,217,11667,"0,0185994686",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,"0,04",Damaging,"28,07","14,86"
"low bq, bad alignment, many samples",UPN2_048,4,106196296,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg1543Ser/c.4629A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1776,54,1838,"0,0293797606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,"0,04",Damaging,"24,73","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106196296,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg1543Ser/c.4629A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5166,81,5290,"0,0153119093",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,"0,04",Damaging,"28,99","16,48"
"low bq, low freq, many artifacts, many samples",UPN2_050,4,106196296,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg1543Ser/c.4629A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),13262,151,13504,"0,011181872",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,"0,04",Damaging,"31,35","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106196296,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg1543Ser/c.4629A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),12504,131,12723,"0,0102963138",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,"0,04",Damaging,"31,34","16,33"
"low bq, low freq, many artifacts, many samples",UPN2_052,4,106196296,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg1543Ser/c.4629A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),12360,126,12559,"0,0100326459",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,"0,04",Damaging,"31,78","20,27"
"low bq, low freq, many artifacts, many samples",UPN2_053,4,106196296,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg1543Ser/c.4629A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),17101,204,17414,"0,0117147123",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,"0,04",Damaging,"31,55","15,53"
"low bq, low freq, many artifacts, many samples",UPN2_055,4,106196296,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg1543Ser/c.4629A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),17762,188,18048,"0,0104166667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,"0,04",Damaging,"30,85","15,02"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,4,106196296,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg1543Ser/c.4629A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1525,31,1564,"0,0198209719",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,"0,04",Damaging,"26,77","15,71"
"low bq, low freq, many artifacts, many samples",UPN2_090,4,106196296,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg1543Ser/c.4629A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),7773,81,7893,"0,0102622577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,"0,04",Damaging,"31,99","17,33"
"low bq, low freq, many artifacts, many samples",UPN2_057,4,106196296,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg1543Ser/c.4629A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),11936,138,12151,"0,01135709",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,"0,04",Damaging,"32,21","17,57"
"low bq, many samples",UPN2_059,4,106196296,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg1543Ser/c.4629A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1520,47,1573,"0,0298792117",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,"0,04",Damaging,"27,88","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_093,4,106196296,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg1543Ser/c.4629A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4104,46,4171,"0,0110285303",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,"0,04",Damaging,"33,52","24,87"
"low bq, many samples",UPN2_064,4,106196296,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg1543Ser/c.4629A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1246,31,1280,"0,02421875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,"0,04",Damaging,"29,27","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_065,4,106196296,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg1543Ser/c.4629A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2959,34,3006,"0,0113107119",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,"0,04",Damaging,"33,19","21,65"
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106196296,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg1543Ser/c.4629A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4781,88,4885,"0,0180143296",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,"0,04",Damaging,"33,51","25,82"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106196296,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg1543Ser/c.4629A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2831,40,2879,"0,0138937131",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,"0,04",Damaging,"31,7","15,23"
"low bq, low freq, many artifacts",UPN2_081,4,106196296,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg1543Ser/c.4629A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2568,58,2640,"0,021969697",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,"0,04",Damaging,"29,77","14,67"
"low freq, many artifacts, many samples",UPN2_041,4,106196300,C,A,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln1545Lys/c.4633C>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4024,58,4108,"0,0141187926",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,45,Damaging,"31,65","28,83"
"low freq, many artifacts, low bq",UPN2_044,4,106196300,C,A,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln1545Lys/c.4633C>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2753,36,2804,"0,0128388017",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,"0,045",Damaging,"32,52","28,5"
"low freq, many artifacts, many samples",UPN2_092,4,106196300,C,A,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln1545Lys/c.4633C>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4480,51,4550,"0,0112087912",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,45,Damaging,"32,09","30,24"
"low freq, many artifacts, many samples",UPN2_006,4,106196300,C,G,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln1545Glu/c.4633C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),5145,53,5284,"0,0100302801",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,79",Neutral,26,Damaging,"32,78","31,32"
"low freq, many samples, low bq",UPN2_001,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4998,104,5151,"0,0201902543",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"30,45","29,7"
"low freq, many samples, low bq",UPN2_014,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),9686,110,9874,"0,0111403686",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"30,29","28,46"
"low freq, many samples, low bq",UPN2_017,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5672,60,5764,"0,0104094379",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"30,55","28,42"
"low freq, many samples, low bq",UPN2_019,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),8391,100,8549,"0,0116972745",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"30,59","28,23"
"low freq, many samples, low bq",UPN2_020,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6957,75,7083,"0,0105887336",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"30,69","28,27"
"low freq, many samples, low bq",UPN2_021,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),7432,104,7595,"0,0136932192",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"30,41","28,86"
"low freq, many samples, low bq",UPN2_002,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6763,99,6915,"0,0143167028",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"30,6","28,66"
"low freq, many artifacts, many samples",UPN2_028,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),7143,81,7275,"0,0111340206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,28,Damaging,"30,67","29,86"
"low freq, many artifacts, many samples",UPN2_029,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),9885,102,10068,"0,0101311085",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,28,Damaging,"30,74","29,17"
"low freq, many samples, low bq",UPN2_030,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),12049,129,12260,"0,0105220228",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"30,57","27,88"
"low freq, many samples, low bq",UPN2_005,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1927,30,1967,"0,0152516523",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"30,66","29,6"
"low freq, many samples, low bq",UPN2_032,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3343,36,3406,"0,0105695831",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"30,62","28,47"
"low bq, low freq, many artifacts, many samples",UPN2_048,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1878,20,1914,"0,0104493208",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,28,Damaging,"28,46","16,15"
"low freq, many samples, low bq",UPN2_035,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),17779,191,18105,"0,0105495719",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"30,56","28,91"
"low freq, many samples, low bq",UPN2_036,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),15702,192,16018,"0,0119865152",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"30,9","29,91"
"low freq, many samples, low bq",UPN2_006,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5146,73,5248,"0,013910061",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"30,1","28,36"
"low freq, many artifacts, many samples",UPN2_037,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),14114,145,14365,"0,0100939784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,28,Damaging,"30,57","28,71"
"low freq, many artifacts, many samples",UPN2_039,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),32537,332,33073,"0,0100383999",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,28,Damaging,"30,68","28,77"
"low freq, many samples, low bq",UPN2_007,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),14799,234,15130,"0,0154659617",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"30,3","27,71"
"low freq, many samples, low bq",UPN2_008,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),24045,309,24566,"0,0125783603",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"30,46","27,66"
"low freq, many samples, low bq",UPN2_009,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),19601,212,19952,"0,0106255012",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"30,53","27,53"
"low freq, many samples, low bq",UPN2_010,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),10002,124,10198,"0,0121592469",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"30,55","29,1"
"low freq, many samples, low bq",UPN2_011,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),12522,185,12802,"0,0144508671",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"30,62","28,75"
"low freq, many samples, low bq",UPN2_058,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),10701,134,10918,"0,0122733101",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"30,7","27,45"
"low bq, low freq, many artifacts, many samples",UPN2_059,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1558,27,1591,"0,0169704588",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,28,Damaging,"28,76","18,41"
"low freq, many samples, low bq",UPN2_012,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6381,85,6515,"0,013046815",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"30,35","28,06"
"low freq, many samples, low bq",UPN2_060,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5902,102,6052,"0,0168539326",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"30,83","29,66"
"low freq, many samples, low bq",UPN2_040,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),32431,363,33049,"0,0109836909",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"30,55","29,52"
"low freq, many samples, low bq",UPN2_013,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3929,49,4008,"0,0122255489",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"30,59","27,45"
"low freq, many artifacts, many samples",UPN2_061,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5119,100,5247,"0,0190585096",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,28,Damaging,"31,29","30,34"
"low freq, many samples, low bq",UPN2_062,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4854,106,4982,"0,0212765957",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"31,1","29,94"
"low freq, many samples, low bq",UPN2_063,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5040,125,5208,"0,0240015361",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"31,01","30,63"
"low freq, many samples, low bq",UPN2_064,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1295,22,1320,"0,0166666667",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"28,9","26,64"
"low freq, many samples, low bq",UPN2_065,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2959,41,3019,"0,0135806558",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"30,56","27,78"
"low freq, many samples, low bq",UPN2_066,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),9018,130,9202,"0,0141273636",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"31,4","30,52"
"low freq, many samples, low bq",UPN2_067,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),9229,134,9426,"0,0142159983",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"31,26","29,97"
"low freq, many samples, low bq",UPN2_068,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6710,115,6864,"0,0167540793",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"31,24","29,83"
"low freq, many artifacts, many samples",UPN2_069,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),7590,122,7769,"0,0157034367",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,28,Damaging,"31,06","29,78"
"low freq, many artifacts, many samples",UPN2_070,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4583,65,4675,"0,0139037433",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,28,Damaging,"31,2","30,45"
"low freq, many samples, low bq",UPN2_071,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4615,92,4723,"0,0194791446",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"30,67","29,97"
"low freq, many samples, low bq",UPN2_072,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4747,102,4868,"0,0209531635",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"30,84","29,6"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2847,48,2911,"0,016489179",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,28,Damaging,"29,93","24,35"
"low freq, many samples, low bq",UPN2_074,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4527,96,4645,"0,0206673843",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"31,13","28,94"
"low freq, many samples, low bq",UPN2_075,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),7713,140,7895,"0,0177327422",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"31,09","29,37"
"low freq, many artifacts, many samples",UPN2_076,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6909,153,7118,"0,0214948019",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,28,Damaging,"31,09","29,99"
"low freq, many samples, low bq",UPN2_077,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),7783,140,7989,"0,0175240956",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"31,07","30,71"
"low freq, many samples, low bq",UPN2_078,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6462,113,6626,"0,0170540296",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"31,05","29,97"
"low freq, many samples, low bq",UPN2_079,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4109,60,4191,"0,0143163923",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"30,77","28,52"
"low freq, many samples, low bq",UPN2_080,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5746,117,5889,"0,0198675497",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"30,97","28,91"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2641,45,2709,"0,0166112957",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,28,Damaging,"29,4","23,36"
"low freq, many samples, low bq",UPN2_082,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),10083,138,10283,"0,0134202081",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"31,2","29,98"
"low freq, many samples, low bq",UPN2_083,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),8793,203,9064,"0,022396293",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"30,96","30,43"
"low freq, many samples, low bq",UPN2_084,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),8953,155,9188,"0,0168698302",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"31,16","30,09"
"low freq, many artifacts, many samples",UPN2_085,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),10432,164,10680,"0,0153558052",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,28,Damaging,"31,27","30,48"
"low freq, many artifacts, many samples",UPN2_086,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),9579,143,9794,"0,014600776",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,28,Damaging,"31,29","30,69"
"low freq, many artifacts",UPN2_087,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),9947,190,10214,"0,0186019189",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,28,Damaging,"30,96","30,06"
"low freq, many samples, low bq",UPN2_088,4,106196301,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1545Pro/c.4634A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),8341,149,8566,"0,0173943498",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,028",Damaging,"31,14","29,72"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_001,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3213,55,3289,"0,016722408",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"26,48","21,49"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_014,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),8030,155,8207,"0,0188863166",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,55","17,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_015,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),11959,227,12235,"0,0185533306",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,79","17,89"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_016,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6156,123,6296,"0,0195362135",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,46","18,33"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_017,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4597,102,4730,"0,021564482",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,57","17,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_018,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6135,127,6301,"0,0201555309",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,62","16,46"
"low bq, bad alignment, many samples",UPN2_019,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6626,157,6815,"0,0230374175",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,6","17,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_020,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5121,114,5258,"0,0216812476",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,55","16,79"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_021,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6117,130,6260,"0,0207667732",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,64","16,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_002,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4376,57,4461,"0,0127774042",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"26,51","18,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_022,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),7347,150,7529,"0,0199229645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,55","18,19"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_023,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),7397,144,7579,"0,0189998681",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,58","17,54"
"low bq, bad alignment, many samples",UPN2_041,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1152,41,1201,"0,0341382182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,53","16,49"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_024,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3894,58,3975,"0,014591195",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,79","17,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_025,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),10957,201,11215,"0,0179224253",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,57","17,71"
"low bq, low freq, many artifacts, many samples",UPN2_026,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),9696,106,9851,"0,0107603289",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"28,06",17
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_027,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),8077,159,8266,"0,0192354222",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,66","17,36"
"low bq, bad alignment, many samples",UPN2_089,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5210,250,5492,"0,0455207575",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,27","15,3"
"low bq, bad alignment, many samples",UPN2_042,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),14070,498,14697,"0,0338844662",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,37","15,9"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_028,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4212,88,4325,"0,0203468208",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,64","16,66"
"low bq, bad alignment, many samples",UPN2_043,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),9390,311,9778,"0,0318060953",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,48","15,9"
"low bq, bad alignment, many samples",UPN2_044,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2288,89,2392,"0,0372073579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,53","15,11"
"low bq, bad alignment, many samples",UPN2_029,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6303,149,6504,"0,0229089791",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,56","17,21"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_030,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),9138,184,9373,"0,0196308546",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,58","16,97"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_031,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5836,117,5979,"0,0195684897",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,7","18,54"
"low bq, bad alignment, many samples",UPN2_045,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),12010,410,12512,"0,0327685422",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,31","15,73"
"low bq, bad alignment, many samples",UPN2_032,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2077,50,2142,"0,0233426704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,84","18,32"
"low bq, bad alignment, many samples",UPN2_046,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),9114,321,9511,"0,0337503943",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,43","16,17"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_033,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6272,120,6426,"0,0186741363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,77","17,92"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_034,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1959,28,2000,"0,014",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,56","16,82"
"low bq, bad alignment, many samples",UPN2_047,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),15385,487,16014,"0,0304108905",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,41","15,33"
"low bq, bad alignment, many samples",UPN2_048,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3561,119,3709,"0,0320841197",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,37","15,42"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_035,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),12881,230,13163,"0,0174732204",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,8","18,03"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_036,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),8493,150,8681,"0,0172791153",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,75","17,15"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_006,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5123,75,5232,"0,0143348624",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"26,36","18,91"
"low bq, bad alignment, many samples",UPN2_049,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6056,208,6310,"0,0329635499",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,5","15,54"
"low bq, bad alignment, many samples",UPN2_050,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),9295,286,9686,"0,0295271526",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,31","15,63"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_037,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),10433,227,10741,"0,0211339726",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,81","17,55"
"low bq, bad alignment, many samples",UPN2_051,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),8843,343,9301,"0,0368777551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,16","15,79"
"low bq, bad alignment, many samples",UPN2_052,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),7627,222,7937,"0,0279702658",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,24","15,22"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_038,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),14213,272,14544,"0,0187018702",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,77","18,21"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_039,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),22208,427,22747,"0,0187717062",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,85","18,01"
"low bq, bad alignment, many samples",UPN2_053,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),11431,372,11924,"0,0311975847",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,45","15,94"
"low bq, bad alignment, many samples",UPN2_054,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6221,193,6468,"0,0298392084",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,37","15,36"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_007,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),10059,137,10279,"0,0133281448",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"26,38","17,74"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_008,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),17476,251,17870,"0,014045887",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"26,53","19,08"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_009,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),13430,221,13772,"0,016047052",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"26,46","18,69"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_010,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5493,86,5617,"0,0153106641",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"26,34","19,58"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_011,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),7619,113,7774,"0,0145356316",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"26,59","19,62"
"low bq, bad alignment, many samples",UPN2_055,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),14347,486,14946,"0,0325170614",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,4","15,73"
"low bq, bad alignment, many samples",UPN2_056,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2428,71,2514,"0,0282418457",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,38","15,92"
"low bq, bad alignment, many samples",UPN2_090,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4893,261,5171,"0,0504737962",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,85","15,37"
"low bq, bad alignment, many samples",UPN2_057,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6548,193,6799,"0,0283865274",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,39","15,1"
"low bq, bad alignment, many samples",UPN2_058,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6118,235,6405,"0,0366900859",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,43","16,31"
"low bq, bad alignment, many samples",UPN2_059,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1894,154,2063,"0,07464857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,33","15,13"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_012,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4548,92,4662,"0,0197340197",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"26,42","20,64"
"low bq, bad alignment, many samples",UPN2_060,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1374,139,1519,"0,0915075708",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"24,97","15,03"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_040,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),23051,431,23620,"0,0182472481",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,77","17,95"
"low bq, low freq, many artifacts, many samples",UPN2_013,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2540,36,2591,"0,0138942493",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"27,23","17,89"
"low bq, bad alignment, many samples",UPN2_091,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4845,248,5104,"0,0485893417",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,01","15,4"
"low bq, bad alignment, many samples",UPN2_092,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2096,108,2218,"0,0486925158",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,06","15,48"
"low bq, bad alignment, many samples",UPN2_093,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1655,108,1767,"0,0611205433",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,25,"14,43"
"low bq, bad alignment, many samples",UPN2_061,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),678,57,738,"0,0772357724",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"24,75",16
"low bq, bad alignment, many samples",UPN2_062,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),858,62,921,"0,0673181325",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,51","14,82"
"low bq, bad alignment, many samples",UPN2_063,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),877,108,987,"0,1094224924",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,29","15,25"
"low bq, bad alignment, many samples",UPN2_064,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1259,115,1378,"0,0834542816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,23","15,14"
"low bq, bad alignment, many samples",UPN2_065,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1081,70,1155,"0,0606060606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,48","15,29"
"low bq, bad alignment, many samples",UPN2_066,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),565,41,608,"0,0674342105",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,31","14,34"
"low bq, bad alignment, many samples",UPN2_067,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),938,87,1032,"0,0843023256",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,07","15,16"
"low bq, bad alignment, many samples",UPN2_068,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),806,64,873,"0,0733104238",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,65","15,11"
"low bq, bad alignment, many samples",UPN2_069,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1431,125,1560,"0,0801282051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"24,92","14,7"
"low bq, bad alignment, many samples",UPN2_070,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),575,44,622,"0,0707395498",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,45","16,07"
"low bq, bad alignment, many samples",UPN2_071,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1377,112,1495,"0,074916388",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,29","14,95"
"low bq, bad alignment, many samples",UPN2_072,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1407,106,1532,"0,0691906005",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"24,74","15,06"
"low bq, bad alignment, many samples",UPN2_073,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1689,157,1853,"0,084727469",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,39","15,03"
"low bq, bad alignment, many samples",UPN2_074,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),852,99,959,"0,1032325339",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,92","15,32"
"low bq, bad alignment, many samples",UPN2_075,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1591,119,1722,"0,0691056911",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,1","15,13"
"low bq, bad alignment, many samples",UPN2_076,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1120,103,1230,"0,0837398374",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,11","15,56"
"low bq, bad alignment, many samples",UPN2_077,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1291,96,1406,"0,0682788051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,13","14,99"
"low bq, bad alignment, many samples",UPN2_078,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1362,110,1479,"0,0743745774",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,49","14,97"
"low bq, bad alignment, many samples",UPN2_079,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1008,100,1117,"0,0895255148",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,09","14,9"
"low bq, bad alignment, many samples",UPN2_080,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1200,72,1279,"0,0562939797",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"24,97","15,08"
"low bq, bad alignment, many samples",UPN2_081,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2423,230,2665,"0,08630394",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,04","15,1"
"low bq, bad alignment, many samples",UPN2_082,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1408,142,1555,"0,091318328",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,27","14,86"
"low bq, bad alignment, many samples",UPN2_083,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1930,192,2132,"0,0900562852",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,46","14,34"
"low bq, bad alignment, many samples",UPN2_084,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1411,131,1549,"0,0845706908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,2","14,75"
"low bq, bad alignment, many samples",UPN2_085,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1252,98,1358,"0,0721649485",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,8","15,34"
"low bq, bad alignment, many samples",UPN2_086,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),968,86,1059,"0,0812086874",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,65","14,78"
"low bq, bad alignment, many samples",UPN2_087,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1986,196,2195,"0,0892938497",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,16","14,89"
"low bq, bad alignment, many samples",UPN2_088,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1257,95,1355,"0,0701107011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,21","15,14"
"low bq, bad alignment, many samples",UPN2_094,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5332,281,5641,"0,0498138628",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,04","15,42"
"low bq, bad alignment, many samples",UPN2_095,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4469,253,4738,"0,0533980583",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"24,94","15,83"
"low bq, bad alignment, many samples",UPN2_096,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5808,309,6136,"0,0503585398",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"24,92","15,06"
"low bq, bad alignment, many samples",UPN2_097,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6709,340,7081,"0,048015817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,1","15,22"
"low bq, bad alignment, many samples",UPN2_098,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4985,244,5248,"0,0464939024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,21","15,56"
"low bq, bad alignment, many samples",UPN2_099,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2754,143,2922,"0,0489390828",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"24,97","15,22"
"low bq, bad alignment, many samples",UPN2_100,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5238,253,5521,"0,0458250317",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"24,89","15,02"
"low bq, bad alignment, many samples",UPN2_101,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3375,190,3579,"0,0530874546",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,13","15,36"
"low bq, bad alignment, many samples",UPN2_102,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3852,220,4094,"0,0537371764",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,24","14,84"
"low bq, bad alignment, many samples",UPN2_103,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5137,243,5395,"0,0450417053",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,11","14,93"
"low bq, bad alignment, many samples",UPN2_104,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6821,373,7231,"0,0515834601",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,11","15,01"
"low bq, bad alignment, many samples",UPN2_105,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5047,239,5310,"0,0450094162",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,1","15,16"
"low bq, bad alignment, many samples",UPN2_106,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),10157,547,10763,"0,0508222615",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"24,9","14,99"
"low bq, bad alignment, many samples",UPN2_107,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),10093,556,10692,"0,0520014964",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,07","15,06"
"low bq, bad alignment, many samples",UPN2_108,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),9322,522,9898,"0,0527379269",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,08","14,85"
"low bq, bad alignment, many samples",UPN2_109,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),8222,373,8633,"0,0432063014",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,14","15,03"
"low bq, bad alignment, many samples",UPN2_110,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),8680,458,9174,"0,0499236974",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,07",15
"low bq, bad alignment",UPN2_111,4,106196302,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1545His/c.4635G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6002,318,6332,"0,0502210992",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,35",Neutral,"0,08",Tolerated,"25,09","15,28"
"inspected, many artifacts",UPN2_063,4,106196303,C,T,stop_gained(HIGH|NONSENSE|Cag/Tag|p.Gln1546*/c.4636C>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),971,20,994,"0,0201207243",0,0,0,0,1,0,0,1,2,NO,NO,COSM211736,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,78","31,35"
"low bq, low freq, many artifacts",UPN2_075,4,106196307,A,G,missense_variant(MODERATE|MISSENSE|cAg/cGg|p.Gln1547Arg/c.4640A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),1683,20,1719,"0,0116346713",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,"0,08",Tolerated,"30,49","28,35"
"low bq, low freq, many artifacts, many samples",UPN2_059,4,106196310,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1548Pro/c.4643A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2035,21,2068,"0,0101547389",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,12",Neutral,32,Damaging,"30,08","16,71"
"low bq, low freq, many artifacts, many samples",UPN2_060,4,106196310,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1548Pro/c.4643A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1486,24,1522,"0,0157687254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,12",Neutral,32,Damaging,"29,57",14
"low bq, low freq, many artifacts, many samples",UPN2_092,4,106196310,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1548Pro/c.4643A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2166,30,2217,"0,0135317997",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,12",Neutral,32,Damaging,"31,66","23,5"
"low bq, low freq, many artifacts, many samples",UPN2_069,4,106196310,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1548Pro/c.4643A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1518,26,1553,"0,0167417901",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,12",Neutral,32,Damaging,"29,7","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106196310,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1548Pro/c.4643A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1497,23,1525,"0,0150819672",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,12",Neutral,32,Damaging,"29,62","17,57"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106196310,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1548Pro/c.4643A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1832,30,1878,"0,0159744409",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,12",Neutral,32,Damaging,"29,91","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_079,4,106196310,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1548Pro/c.4643A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1098,20,1121,"0,0178412132",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,12",Neutral,32,Damaging,"29,99","15,3"
"low bq, low freq, many artifacts, many samples",UPN2_080,4,106196310,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1548Pro/c.4643A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1252,20,1278,"0,0156494523",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,12",Neutral,32,Damaging,"30,04","17,55"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106196310,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1548Pro/c.4643A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2651,31,2696,"0,0114985163",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,12",Neutral,32,Damaging,"30,07","16,94"
"low bq, low freq, many artifacts, many samples",UPN2_082,4,106196310,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1548Pro/c.4643A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1485,22,1517,"0,0145023072",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,12",Neutral,32,Damaging,"29,8","17,55"
"low bq, low freq, many artifacts, many samples",UPN2_083,4,106196310,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1548Pro/c.4643A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2128,26,2168,"0,0119926199",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,12",Neutral,32,Damaging,"29,72","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_084,4,106196310,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1548Pro/c.4643A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1505,22,1536,"0,0143229167",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,12",Neutral,32,Damaging,"29,86","18,45"
"low bq, low freq, many artifacts",UPN2_087,4,106196310,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln1548Pro/c.4643A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2139,28,2177,"0,0128617363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,12",Neutral,32,Damaging,"29,66","17,61"
"low bq, low freq, many artifacts",UPN2_072,4,106196312,C,T,missense_variant(MODERATE|MISSENSE|Cca/Tca|p.Pro1549Ser/c.4645C>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),1486,25,1525,"0,0163934426",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,02",Neutral,"0,123",Tolerated,"31,3","29,36"
"low bq, low freq, many artifacts, many samples",UPN2_059,4,106196316,A,C,missense_variant(MODERATE|MISSENSE|cAt/cCt|p.His1550Pro/c.4649A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2031,32,2070,"0,0154589372",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,84",Neutral,29,Damaging,"29,04","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_060,4,106196316,A,C,missense_variant(MODERATE|MISSENSE|cAt/cCt|p.His1550Pro/c.4649A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1485,29,1523,"0,0190413657",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,84",Neutral,29,Damaging,"28,8","14,24"
"low bq, many samples",UPN2_063,4,106196316,A,C,missense_variant(MODERATE|MISSENSE|cAt/cCt|p.His1550Pro/c.4649A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),971,24,998,"0,0240480962",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,84",Neutral,29,Damaging,"29,04","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_064,4,106196316,A,C,missense_variant(MODERATE|MISSENSE|cAt/cCt|p.His1550Pro/c.4649A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1363,23,1391,"0,016534867",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,84",Neutral,29,Damaging,"28,75","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_067,4,106196316,A,C,missense_variant(MODERATE|MISSENSE|cAt/cCt|p.His1550Pro/c.4649A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1007,20,1030,"0,0194174757",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,84",Neutral,29,Damaging,"28,8","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_069,4,106196316,A,C,missense_variant(MODERATE|MISSENSE|cAt/cCt|p.His1550Pro/c.4649A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1521,22,1553,"0,0141661301",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,84",Neutral,29,Damaging,"28,9","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_071,4,106196316,A,C,missense_variant(MODERATE|MISSENSE|cAt/cCt|p.His1550Pro/c.4649A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1465,25,1499,"0,0166777852",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,84",Neutral,29,Damaging,"28,81","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106196316,A,C,missense_variant(MODERATE|MISSENSE|cAt/cCt|p.His1550Pro/c.4649A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1488,28,1525,"0,0183606557",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,84",Neutral,29,Damaging,"28,47","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106196316,A,C,missense_variant(MODERATE|MISSENSE|cAt/cCt|p.His1550Pro/c.4649A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1828,41,1879,"0,0218201171",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,84",Neutral,29,Damaging,"28,57","15,73"
"low bq, low freq, many artifacts, many samples",UPN2_075,4,106196316,A,C,missense_variant(MODERATE|MISSENSE|cAt/cCt|p.His1550Pro/c.4649A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1682,24,1717,"0,0139778684",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,84",Neutral,29,Damaging,"29,12","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_076,4,106196316,A,C,missense_variant(MODERATE|MISSENSE|cAt/cCt|p.His1550Pro/c.4649A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1204,26,1237,"0,0210185934",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,84",Neutral,29,Damaging,"28,82","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_077,4,106196316,A,C,missense_variant(MODERATE|MISSENSE|cAt/cCt|p.His1550Pro/c.4649A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1373,22,1405,"0,015658363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,84",Neutral,29,Damaging,"28,31",14
"low bq, low freq, many artifacts, many samples",UPN2_078,4,106196316,A,C,missense_variant(MODERATE|MISSENSE|cAt/cCt|p.His1550Pro/c.4649A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1456,22,1479,"0,0148749155",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,84",Neutral,29,Damaging,"28,81","14,91"
"low bq, many samples",UPN2_079,4,106196316,A,C,missense_variant(MODERATE|MISSENSE|cAt/cCt|p.His1550Pro/c.4649A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1093,28,1123,"0,0249332146",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,84",Neutral,29,Damaging,"28,7","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_080,4,106196316,A,C,missense_variant(MODERATE|MISSENSE|cAt/cCt|p.His1550Pro/c.4649A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1252,23,1281,"0,0179547229",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,84",Neutral,29,Damaging,"28,46",14
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106196316,A,C,missense_variant(MODERATE|MISSENSE|cAt/cCt|p.His1550Pro/c.4649A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2632,52,2696,"0,0192878338",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,84",Neutral,29,Damaging,"29,29","14,73"
"low bq, many samples",UPN2_082,4,106196316,A,C,missense_variant(MODERATE|MISSENSE|cAt/cCt|p.His1550Pro/c.4649A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1473,34,1516,"0,0224274406",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,84",Neutral,29,Damaging,"28,63",14
"low bq, low freq, many artifacts, many samples",UPN2_083,4,106196316,A,C,missense_variant(MODERATE|MISSENSE|cAt/cCt|p.His1550Pro/c.4649A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2133,35,2173,"0,0161067648",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,84",Neutral,29,Damaging,"28,75","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_084,4,106196316,A,C,missense_variant(MODERATE|MISSENSE|cAt/cCt|p.His1550Pro/c.4649A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1505,32,1540,"0,0207792208",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,84",Neutral,29,Damaging,"28,94","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_085,4,106196316,A,C,missense_variant(MODERATE|MISSENSE|cAt/cCt|p.His1550Pro/c.4649A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1321,20,1347,"0,0148478099",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,84",Neutral,29,Damaging,"28,76","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_087,4,106196316,A,C,missense_variant(MODERATE|MISSENSE|cAt/cCt|p.His1550Pro/c.4649A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2126,46,2179,"0,0211106012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,84",Neutral,29,Damaging,"28,91","15,59"
"low bq, low freq, many artifacts",UPN2_088,4,106196316,A,C,missense_variant(MODERATE|MISSENSE|cAt/cCt|p.His1550Pro/c.4649A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1320,26,1348,"0,0192878338",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,84",Neutral,29,Damaging,"28,81","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_001,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3237,48,3295,"0,0145675266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"32,92","16,1"
"low bq, low freq, many artifacts, many samples",UPN2_014,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),8127,104,8279,"0,0125619036",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"32,99","17,65"
"low bq, low freq, many artifacts, many samples",UPN2_015,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),12204,138,12375,"0,0111515152",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"33,22","17,28"
"low bq, low freq, many artifacts, many samples",UPN2_016,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6210,84,6329,"0,0132722389",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"33,04","17,06"
"low bq, low freq, many artifacts, many samples",UPN2_019,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6760,83,6872,"0,0120779977",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"33,12","18,54"
"low bq, low freq, many artifacts, many samples",UPN2_020,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5191,59,5271,"0,011193322",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"33,08","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_021,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6199,84,6309,"0,0133143129",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"33,03","18,61"
"low bq, low freq, many artifacts, many samples",UPN2_002,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4339,63,4417,"0,0142630745",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"32,52","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_022,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7522,98,7651,"0,0128087832",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"33,26","17,2"
"low bq, low freq, many artifacts, many samples",UPN2_023,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7533,83,7647,"0,0108539296",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"33,03","17,61"
"low bq, low freq, many artifacts, many samples",UPN2_026,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9811,119,9966,"0,011940598",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"33,11","16,76"
"low bq, low freq, many artifacts, many samples",UPN2_027,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),8221,95,8347,"0,0113813346",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"33,16","17,68"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),14572,241,14890,"0,0161853593",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"32,63","17,46"
"low bq, low freq, many artifacts, many samples",UPN2_028,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4261,56,4339,"0,0129061996",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"33,1","17,86"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9600,167,9823,"0,0170009162",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"32,78","17,23"
"low bq, low freq, many artifacts, many samples",UPN2_029,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6420,78,6526,"0,0119521912",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"33,15","17,9"
"low bq, low freq, many artifacts, many samples",UPN2_030,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9313,104,9444,"0,0110122829",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"33,09","17,33"
"low bq, low freq, many artifacts, many samples",UPN2_031,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5919,61,6011,"0,0101480619",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"33,1","16,62"
"low bq, low freq, many artifacts, many samples",UPN2_005,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1141,21,1165,"0,0180257511",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"32,62","16,57"
"low bq, low freq, many artifacts, many samples",UPN2_045,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),12436,184,12707,"0,0144802078",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"32,71","16,88"
"low bq, low freq, many artifacts, many samples",UPN2_046,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9421,145,9619,"0,0150743321",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"32,63","16,3"
"low bq, low freq, many artifacts, many samples",UPN2_034,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1966,28,2005,"0,0139650873",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"32,97","16,07"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),15853,213,16161,"0,0131798775",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"32,67","16,79"
"low bq, low freq, many artifacts, many samples",UPN2_048,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3643,54,3723,"0,0145044319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"32,74","17,65"
"low bq, low freq, many artifacts, many samples",UPN2_035,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),13047,170,13258,"0,0128224468",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"33,26","17,33"
"low bq, low freq, many artifacts, many samples",UPN2_006,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5153,72,5260,"0,0136882129",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"32,76","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6254,91,6375,"0,0142745098",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"32,77","17,01"
"low bq, low freq, many artifacts, many samples",UPN2_050,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9626,145,9807,"0,0147853574",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"32,61","16,52"
"low bq, low freq, many artifacts, many samples",UPN2_037,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),10643,108,10799,"0,010000926",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"33,13","18,27"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9174,161,9396,"0,017134951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"32,69","17,69"
"low bq, low freq, many artifacts, many samples",UPN2_052,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7872,116,8033,"0,0144404332",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"32,64","17,16"
"low bq, low freq, many artifacts, many samples",UPN2_039,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),22548,243,22896,"0,0106132075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"33,12","17,37"
"low bq, low freq, many artifacts, many samples",UPN2_053,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),11778,171,12008,"0,0142405063",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"32,7","17,26"
"low bq, low freq, many artifacts, many samples",UPN2_054,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6371,104,6536,"0,0159118727",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"32,6","16,77"
"low bq, low freq, many artifacts, many samples",UPN2_007,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),10173,147,10351,"0,0142015264",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"32,88","16,39"
"low bq, low freq, many artifacts, many samples",UPN2_008,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),17411,272,17738,"0,0153343105",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"32,69","18,64"
"low bq, low freq, many artifacts, many samples",UPN2_009,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),13497,209,13760,"0,0151889535",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"32,69","16,04"
"low bq, low freq, many artifacts, many samples",UPN2_010,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5425,95,5548,"0,0171232877",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"32,61","17,24"
"low bq, low freq, many artifacts, many samples",UPN2_011,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7516,121,7655,"0,0158066623",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"32,64","16,19"
"low bq, low freq, many artifacts, many samples",UPN2_055,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),14772,225,15079,"0,0149214139",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"32,69","16,78"
"low bq, many samples",UPN2_056,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2431,56,2508,"0,0223285486",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"32,45","21,09"
"low bq, low freq, many artifacts, many samples",UPN2_057,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6700,121,6865,"0,0176256373",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"32,76","16,62"
"low bq, low freq, many artifacts, many samples",UPN2_058,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6331,86,6455,"0,0133230054",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"32,71","16,72"
"low bq, low freq, many artifacts, many samples",UPN2_012,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4522,78,4614,"0,0169050715",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"32,73","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_060,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1491,23,1522,"0,0151116951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"31,29","16,09"
"low bq, low freq, many artifacts, many samples",UPN2_040,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),23397,277,23758,"0,0116592306",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"33,09",17
"low bq, low freq, many artifacts, many samples",UPN2_013,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2379,47,2432,"0,0193256579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"32,86","15,79"
"low bq, low freq, many artifacts, many samples",UPN2_075,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1684,24,1716,"0,013986014",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"31,54","18,25"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2646,34,2696,"0,012611276",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"31,55","15,97"
"low bq, low freq, many artifacts",UPN2_085,4,106196317,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1550Gln/c.4650T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1317,20,1347,"0,0148478099",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,428,Tolerated,"31,4","17,95"
"low bq, low freq, many artifacts, many samples",UPN2_001,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3228,46,3293,"0,0139690252",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,59","18,17"
"low bq, low freq, many artifacts, many samples",UPN2_002,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4333,65,4417,"0,0147158705",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,56","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_041,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1157,20,1187,"0,0168491997",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,67","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_089,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5362,61,5460,"0,0111721612",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,25","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),14552,204,14889,"0,0137013903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"28,96","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),9645,124,9824,"0,0126221498",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,17","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_044,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2343,37,2410,"0,0153526971",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"28,98","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_045,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),12434,183,12706,"0,0144026444",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"28,98","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_046,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),9405,153,9618,"0,0159076731",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,12","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),15774,226,16162,"0,0139834179",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,06","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_048,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3631,58,3723,"0,0155788343",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,33","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_006,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5158,71,5262,"0,0134929685",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,65","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6218,102,6372,"0,016007533",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"28,94","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_050,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),9604,138,9805,"0,0140744518",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"28,92","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),9217,120,9394,"0,0127741111",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,1","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_052,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),7885,105,8031,"0,0130743369",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,02","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_053,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),11749,173,12004,"0,0144118627",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"28,85","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_054,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6408,85,6535,"0,013006886",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"28,86","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_007,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),10143,154,10350,"0,0148792271",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,77","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_008,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),17417,212,17736,"0,0119530898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,68","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_009,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),13494,189,13762,"0,013733469",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,77","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_010,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5435,82,5548,"0,0147801009",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,49","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_011,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),7492,117,7653,"0,0152881223",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,66","15,97"
"low bq, low freq, many artifacts, many samples",UPN2_055,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),14819,185,15115,"0,0122394972",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,23","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_056,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2443,41,2508,"0,0163476874",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,06","15,41"
"low bq, low freq, many artifacts, many samples",UPN2_090,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4732,62,4815,"0,0128764278",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,22","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_057,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6730,88,6863,"0,0128223809",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"28,97","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_058,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6331,85,6455,"0,0131680868",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,09","14,74"
"low bq, many samples",UPN2_059,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2015,48,2070,"0,0231884058",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"28,3","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_012,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4541,52,4615,"0,0112676056",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,7","14,83"
"low bq, many samples",UPN2_060,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1481,39,1522,"0,0256241787",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"27,97","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_013,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2383,35,2432,"0,0143914474",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,9","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_091,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5071,69,5162,"0,013366912",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,56","15,77"
"low bq, low freq, many artifacts, many samples",UPN2_093,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1753,20,1783,"0,0112170499",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,44","15,05"
"low bq, many samples",UPN2_062,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),897,25,928,"0,0269396552",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"27,79",14
"low bq, many samples",UPN2_063,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),964,25,997,"0,0250752257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"28,84","14,28"
"low bq, many samples",UPN2_064,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1346,37,1391,"0,0265995687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"28,35","15,54"
"low bq, many samples",UPN2_065,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1093,40,1144,"0,034965035",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"28,14","14,73"
"low bq, many samples",UPN2_067,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),999,27,1030,"0,0262135922",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"27,77","14,26"
"low bq, many samples",UPN2_068,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),846,26,879,"0,0295790671",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"28,58","15,54"
"low bq, many samples",UPN2_069,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1493,44,1552,"0,0283505155",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"27,98","14,61"
"low bq, many samples",UPN2_071,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1429,48,1499,"0,0320213476",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"28,2","15,46"
"low bq, many samples",UPN2_072,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1484,40,1525,"0,0262295082",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"28,12","14,9"
"low bq, many samples",UPN2_073,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1804,62,1879,"0,0329962746",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"28,43","15,05"
"low bq, many samples",UPN2_074,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),932,22,957,"0,0229885057",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"28,13","14,91"
"low bq, many samples",UPN2_075,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1659,49,1716,"0,0285547786",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"28,48","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_076,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1207,26,1237,"0,0210185934",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"27,78",14
"low bq, many samples",UPN2_077,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1337,52,1407,"0,0369580668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"27,98","15,31"
"low bq, many samples",UPN2_078,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1424,44,1480,"0,0297297297",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"28,25","14,61"
"low bq, many samples",UPN2_079,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1088,30,1123,"0,0267141585",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"27,82","14,73"
"low bq, many samples",UPN2_080,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1247,30,1281,"0,0234192037",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"27,9",14
"low bq, many samples",UPN2_081,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2611,67,2698,"0,0248332098",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"28,48","14,97"
"low bq, many samples",UPN2_082,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1463,48,1515,"0,0316831683",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"28,11","14,54"
"low bq, many samples",UPN2_083,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2086,71,2173,"0,032673723",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"28,21","15,18"
"low bq, many samples",UPN2_084,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1495,41,1540,"0,0266233766",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"27,89","14,85"
"low bq, many samples",UPN2_085,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1300,38,1347,"0,0282108389",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"28,27","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_086,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),984,22,1009,"0,0218037661",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"28,58","14,64"
"low bq, many samples",UPN2_087,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2103,56,2179,"0,0256998623",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"28,22","14,25"
"low bq, many samples",UPN2_088,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1298,35,1347,"0,0259836674",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"28,43","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_094,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5594,73,5691,"0,0128272711",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,37","14,18"
"low bq, low freq, many artifacts, many samples",UPN2_095,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4700,73,4792,"0,0152337229",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,25","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_096,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6098,70,6193,"0,0113030841",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,33","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_097,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),7003,91,7121,"0,0127791041",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,45","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_098,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5147,67,5249,"0,0127643361",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,17","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_099,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2871,41,2930,"0,0139931741",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,24","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_100,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5423,73,5513,"0,0132414293",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,46","15,3"
"low bq, low freq, many artifacts, many samples",UPN2_101,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3516,51,3579,"0,0142497904",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,18","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_102,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4024,47,4081,"0,0115167851",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,3","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_103,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5314,80,5407,"0,0147956353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,16","14,18"
"low bq, low freq, many artifacts, many samples",UPN2_104,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),7110,98,7221,"0,0135715275",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,28","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_105,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5270,55,5342,"0,0102957694",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,23","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_106,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),10634,153,10847,"0,0141052826",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,4","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_107,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),10555,142,10767,"0,0131884462",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,22","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_108,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),9728,135,9924,"0,0136033857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,42","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_109,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),8515,108,8648,"0,0124884366",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,38","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_110,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),9037,151,9230,"0,0163596966",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,13","14,82"
"low bq, low freq, many artifacts",UPN2_111,4,106196319,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His1551Pro/c.4652A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6244,92,6365,"0,0144540456",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,19",Neutral,304,Tolerated,"29,29","14,47"
"low bq, low freq, many artifacts",UPN2_071,4,106196319,A,G,missense_variant(MODERATE|MISSENSE|cAc/cGc|p.His1551Arg/c.4652A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),1429,20,1499,"0,0133422282",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,"0,738",Tolerated,"28,2","26,3"
"low bq, low freq, many artifacts",UPN2_087,4,106196321,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro1552Thr/c.4654C>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2144,24,2179,"0,0110142267",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,"0,01",Damaging,"31,08","19,88"
"low bq, low freq, many artifacts",UPN2_064,4,106196326,G,C,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln1553His/c.4659G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1368,21,1391,"0,0150970525",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,34,Damaging,"30,71","14,33"
"low bq, low freq, many artifacts",UPN2_082,4,106196327,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr1554Pro/c.4660A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1484,21,1514,"0,0138705416",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,296,Tolerated,"30,55","17,81"
"low bq, low freq, many artifacts",UPN2_048,4,106196327,A,T,missense_variant(MODERATE|MISSENSE|Aca/Tca|p.Thr1554Ser/c.4660A>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),3639,57,3720,"0,0153225806",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,42",Neutral,1,Tolerated,"32,07","29,82"
"low bq, low freq, many artifacts",UPN2_078,4,106196327,A,T,missense_variant(MODERATE|MISSENSE|Aca/Tca|p.Thr1554Ser/c.4660A>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),1438,23,1477,"0,0155721056",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,42",Neutral,1,Tolerated,"30,78","28,22"
"low bq, low freq, many artifacts, many samples",UPN2_059,4,106196332,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu1555Asp/c.4665G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2023,30,2063,"0,0145419292",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,142,Tolerated,"29,93","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_065,4,106196332,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu1555Asp/c.4665G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1122,20,1145,"0,0174672489",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,142,Tolerated,"30,19","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106196332,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu1555Asp/c.4665G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2653,31,2695,"0,0115027829",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,142,Tolerated,"29,79","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_082,4,106196332,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu1555Asp/c.4665G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1485,20,1512,"0,0132275132",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,142,Tolerated,"29,69","15,9"
"low bq, low freq, many artifacts, many samples",UPN2_083,4,106196332,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu1555Asp/c.4665G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2143,22,2170,"0,0101382488",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,142,Tolerated,"29,76",16
"low bq, low freq, many artifacts",UPN2_087,4,106196332,G,C,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu1555Asp/c.4665G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2133,29,2176,"0,0133272059",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,142,Tolerated,"29,18",14
"low bq, low freq, many artifacts, many samples",UPN2_001,4,106196333,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1556Thr/c.4666T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3241,35,3291,"0,0106350653",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,47",Neutral,58,Tolerated,"31,91","15,63"
"low bq, low freq, many artifacts, many samples",UPN2_016,4,106196333,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1556Thr/c.4666T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6242,65,6325,"0,0102766798",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,47",Neutral,58,Tolerated,"32,19","17,12"
"low bq, low freq, many artifacts, many samples",UPN2_017,4,106196333,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1556Thr/c.4666T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4694,49,4767,"0,0102790015",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,47",Neutral,58,Tolerated,"32,33","18,88"
"low bq, low freq, many artifacts, many samples",UPN2_002,4,106196333,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1556Thr/c.4666T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4346,49,4411,"0,0111085922",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,47",Neutral,58,Tolerated,"31,81","15,31"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106196333,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1556Thr/c.4666T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),14505,213,14829,"0,0143637467",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,47",Neutral,58,Tolerated,"31,11","17,49"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106196333,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1556Thr/c.4666T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9580,135,9789,"0,0137909899",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,47",Neutral,58,Tolerated,"31,27","16,21"
"low bq, low freq, many artifacts, many samples",UPN2_045,4,106196333,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1556Thr/c.4666T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),12401,154,12655,"0,0121691031",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,47",Neutral,58,Tolerated,"31,15","16,29"
"low bq, low freq, many artifacts, many samples",UPN2_032,4,106196333,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1556Thr/c.4666T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2128,25,2160,"0,0115740741",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,47",Neutral,58,Tolerated,"32,3","17,16"
"low bq, low freq, many artifacts, many samples",UPN2_046,4,106196333,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1556Thr/c.4666T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9427,103,9581,"0,0107504436",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,47",Neutral,58,Tolerated,"31,26","16,44"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106196333,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1556Thr/c.4666T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),15820,189,16117,"0,0117267482",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,47",Neutral,58,Tolerated,"31,06","16,16"
"low bq, low freq, many artifacts, many samples",UPN2_048,4,106196333,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1556Thr/c.4666T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3632,52,3710,"0,0140161725",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,47",Neutral,58,Tolerated,"31,07","19,35"
"low bq, low freq, many artifacts, many samples",UPN2_006,4,106196333,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1556Thr/c.4666T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5159,57,5246,"0,0108654213",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,47",Neutral,58,Tolerated,"31,97","17,02"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106196333,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1556Thr/c.4666T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6240,83,6357,"0,0130564732",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,47",Neutral,58,Tolerated,"31,32","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_050,4,106196333,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1556Thr/c.4666T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9576,125,9777,"0,0127851079",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,47",Neutral,58,Tolerated,"31,27","15,45"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106196333,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1556Thr/c.4666T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9184,122,9356,"0,0130397606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,47",Neutral,58,Tolerated,"31,06","17,6"
"low bq, low freq, many artifacts, many samples",UPN2_052,4,106196333,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1556Thr/c.4666T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7843,99,7993,"0,0123858376",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,47",Neutral,58,Tolerated,"31,19","16,46"
"low bq, low freq, many artifacts, many samples",UPN2_053,4,106196333,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1556Thr/c.4666T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),11724,147,11967,"0,0122837804",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,47",Neutral,58,Tolerated,"31,05","17,22"
"low bq, low freq, many artifacts, many samples",UPN2_054,4,106196333,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1556Thr/c.4666T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6377,73,6503,"0,0112255882",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,47",Neutral,58,Tolerated,"31,02","18,32"
"low bq, low freq, many artifacts, many samples",UPN2_007,4,106196333,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1556Thr/c.4666T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),10132,143,10336,"0,0138351393",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,47",Neutral,58,Tolerated,"32,07","17,53"
"low bq, low freq, many artifacts, many samples",UPN2_008,4,106196333,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1556Thr/c.4666T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),17439,187,17698,"0,0105661657",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,47",Neutral,58,Tolerated,"32,01","15,85"
"low bq, low freq, many artifacts, many samples",UPN2_009,4,106196333,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1556Thr/c.4666T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),13519,153,13734,"0,0111402359",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,47",Neutral,58,Tolerated,"31,91","17,31"
"low bq, low freq, many artifacts, many samples",UPN2_010,4,106196333,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1556Thr/c.4666T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5447,60,5534,"0,0108420672",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,47",Neutral,58,Tolerated,"31,88","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_011,4,106196333,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1556Thr/c.4666T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7528,83,7638,"0,010866719",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,47",Neutral,58,Tolerated,"31,98","15,61"
"low bq, low freq, many artifacts, many samples",UPN2_055,4,106196333,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1556Thr/c.4666T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),14776,189,15050,"0,0125581395",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,47",Neutral,58,Tolerated,"31,11","15,96"
"low bq, low freq, many artifacts, many samples",UPN2_056,4,106196333,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1556Thr/c.4666T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2455,27,2499,"0,0108043217",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,47",Neutral,58,Tolerated,"31,2","16,78"
"low bq, low freq, many artifacts, many samples",UPN2_057,4,106196333,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1556Thr/c.4666T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6712,76,6835,"0,0111192392",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,47",Neutral,58,Tolerated,"31,3","15,25"
"low bq, low freq, many artifacts, many samples",UPN2_058,4,106196333,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1556Thr/c.4666T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6309,73,6428,"0,011356565",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,47",Neutral,58,Tolerated,"31,29","15,49"
"low bq, low freq, many artifacts, many samples",UPN2_012,4,106196333,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1556Thr/c.4666T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4523,61,4604,"0,0132493484",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,47",Neutral,58,Tolerated,"32,16","19,08"
"low bq, low freq, many artifacts, many samples",UPN2_013,4,106196333,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1556Thr/c.4666T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2383,29,2427,"0,0119489081",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,47",Neutral,58,Tolerated,"32,09","15,76"
"low bq, low freq, many artifacts, many samples",UPN2_093,4,106196333,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1556Thr/c.4666T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1774,21,1800,"0,0116666667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,47",Neutral,58,Tolerated,"31,87","19,43"
"low bq, low freq, many artifacts",UPN2_063,4,106196333,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1556Thr/c.4666T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),960,27,996,"0,0271084337",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,47",Neutral,"0,058",Tolerated,"29,64","26,07"
"low bq, low freq, many artifacts",UPN2_087,4,106196333,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1556Thr/c.4666T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2115,28,2177,"0,0128617363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,47",Neutral,58,Tolerated,"29,55","17,14"
"low bq, low freq, many artifacts, many samples",UPN2_059,4,106196333,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser1556Ala/c.4666T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),2015,25,2063,"0,0121182744",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,18",Neutral,283,Tolerated,"29,76","15,72"
"low bq, many samples",UPN2_071,4,106196333,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser1556Ala/c.4666T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),1439,38,1495,"0,0254180602",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,18",Neutral,283,Tolerated,"29,57","17,71"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106196333,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser1556Ala/c.4666T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),1838,20,1871,"0,0106894709",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,18",Neutral,283,Tolerated,"29,79",14
"low bq, low freq, many artifacts, many samples",UPN2_083,4,106196333,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser1556Ala/c.4666T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),2129,22,2169,"0,010142923",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,18",Neutral,283,Tolerated,"29,56","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_084,4,106196333,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser1556Ala/c.4666T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),1503,23,1537,"0,014964216",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,18",Neutral,283,Tolerated,"29,68",14
"low bq, low freq, many artifacts",UPN2_087,4,106196333,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser1556Ala/c.4666T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),2115,33,2177,"0,015158475",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,18",Neutral,283,Tolerated,"29,55","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_059,4,106196336,G,C,missense_variant(MODERATE|MISSENSE|Gtc/Ctc|p.Val1557Leu/c.4669G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2029,24,2063,"0,0116335434",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,02",Neutral,"0,19",Tolerated,"30,73",14
"low bq, low freq, many artifacts, many samples",UPN2_060,4,106196336,G,C,missense_variant(MODERATE|MISSENSE|Gtc/Ctc|p.Val1557Leu/c.4669G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1485,24,1519,"0,0157998683",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,02",Neutral,"0,19",Tolerated,"30,69","14,54"
"low bq, many samples",UPN2_071,4,106196336,G,C,missense_variant(MODERATE|MISSENSE|Gtc/Ctc|p.Val1557Leu/c.4669G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1457,34,1494,"0,0227576975",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,02",Neutral,"0,19",Tolerated,"30,64","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106196336,G,C,missense_variant(MODERATE|MISSENSE|Gtc/Ctc|p.Val1557Leu/c.4669G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1490,21,1521,"0,0138067061",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,02",Neutral,"0,19",Tolerated,"30,4","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_080,4,106196336,G,C,missense_variant(MODERATE|MISSENSE|Gtc/Ctc|p.Val1557Leu/c.4669G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1252,22,1280,"0,0171875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,02",Neutral,"0,19",Tolerated,"30,4","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106196336,G,C,missense_variant(MODERATE|MISSENSE|Gtc/Ctc|p.Val1557Leu/c.4669G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2656,29,2696,"0,0107566766",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,02",Neutral,"0,19",Tolerated,"30,54","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_083,4,106196336,G,C,missense_variant(MODERATE|MISSENSE|Gtc/Ctc|p.Val1557Leu/c.4669G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2139,25,2169,"0,0115260489",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,02",Neutral,"0,19",Tolerated,"30,5","14,52"
"low bq, low freq, many artifacts",UPN2_087,4,106196336,G,C,missense_variant(MODERATE|MISSENSE|Gtc/Ctc|p.Val1557Leu/c.4669G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2133,29,2177,"0,0133210841",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,02",Neutral,"0,19",Tolerated,"30,53","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_014,4,106196337,T,A,missense_variant(MODERATE|MISSENSE|gTc/gAc|p.Val1557Asp/c.4670T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),8133,89,8266,"0,0107669973",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,48",Neutral,0,Damaging,"32,96","18,96"
"low bq, low freq, many artifacts, many samples",UPN2_016,4,106196337,T,A,missense_variant(MODERATE|MISSENSE|gTc/gAc|p.Val1557Asp/c.4670T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6225,66,6324,"0,0104364326",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,48",Neutral,0,Damaging,"33,08","20,08"
"low bq, low freq, many artifacts, many samples",UPN2_022,4,106196337,T,A,missense_variant(MODERATE|MISSENSE|gTc/gAc|p.Val1557Asp/c.4670T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7518,78,7630,"0,0102228047",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,48",Neutral,0,Damaging,"33,24","20,19"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106196337,T,A,missense_variant(MODERATE|MISSENSE|gTc/gAc|p.Val1557Asp/c.4670T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),14537,171,14811,"0,011545473",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,48",Neutral,0,Damaging,"32,41","19,15"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106196337,T,A,missense_variant(MODERATE|MISSENSE|gTc/gAc|p.Val1557Asp/c.4670T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9618,98,9784,"0,0100163532",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,48",Neutral,0,Damaging,"32,39","16,3"
"low bq, low freq, many artifacts, many samples",UPN2_045,4,106196337,T,A,missense_variant(MODERATE|MISSENSE|gTc/gAc|p.Val1557Asp/c.4670T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),12404,129,12642,"0,0102040816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,48",Neutral,0,Damaging,"32,43","18,3"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106196337,T,A,missense_variant(MODERATE|MISSENSE|gTc/gAc|p.Val1557Asp/c.4670T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),15810,190,16107,"0,0117961135",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,48",Neutral,0,Damaging,"32,32","18,45"
"low bq, low freq, many artifacts, many samples",UPN2_050,4,106196337,T,A,missense_variant(MODERATE|MISSENSE|gTc/gAc|p.Val1557Asp/c.4670T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9552,130,9771,"0,0133046771",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,48",Neutral,0,Damaging,"32,33","18,59"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106196337,T,A,missense_variant(MODERATE|MISSENSE|gTc/gAc|p.Val1557Asp/c.4670T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9203,108,9347,"0,0115545095",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,48",Neutral,0,Damaging,"32,3","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_052,4,106196337,T,A,missense_variant(MODERATE|MISSENSE|gTc/gAc|p.Val1557Asp/c.4670T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7847,91,7981,"0,0114020799",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,48",Neutral,0,Damaging,"32,47","19,48"
"low bq, low freq, many artifacts, many samples",UPN2_053,4,106196337,T,A,missense_variant(MODERATE|MISSENSE|gTc/gAc|p.Val1557Asp/c.4670T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),11760,138,11961,"0,0115374969",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,48",Neutral,0,Damaging,"32,33","17,04"
"low bq, low freq, many artifacts, many samples",UPN2_054,4,106196337,T,A,missense_variant(MODERATE|MISSENSE|gTc/gAc|p.Val1557Asp/c.4670T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6387,72,6499,"0,0110786275",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,48",Neutral,0,Damaging,"32,28","19,07"
"low bq, low freq, many artifacts, many samples",UPN2_011,4,106196337,T,A,missense_variant(MODERATE|MISSENSE|gTc/gAc|p.Val1557Asp/c.4670T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7512,82,7634,"0,01074142",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,48",Neutral,0,Damaging,"32,72","16,55"
"low bq, low freq, many artifacts, many samples",UPN2_055,4,106196337,T,A,missense_variant(MODERATE|MISSENSE|gTc/gAc|p.Val1557Asp/c.4670T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),14783,182,15041,"0,0121002593",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,48",Neutral,0,Damaging,"32,4","18,38"
"low bq, low freq, many artifacts, many samples",UPN2_056,4,106196337,T,A,missense_variant(MODERATE|MISSENSE|gTc/gAc|p.Val1557Asp/c.4670T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2443,39,2498,"0,01561249",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,48",Neutral,0,Damaging,"32,32","19,64"
"low bq, low freq, many artifacts, many samples",UPN2_057,4,106196337,T,A,missense_variant(MODERATE|MISSENSE|gTc/gAc|p.Val1557Asp/c.4670T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6715,70,6834,"0,0102429031",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,48",Neutral,0,Damaging,"32,29","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_058,4,106196337,T,A,missense_variant(MODERATE|MISSENSE|gTc/gAc|p.Val1557Asp/c.4670T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6306,88,6425,"0,0136964981",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,48",Neutral,0,Damaging,"32,27","19,01"
"low bq, low freq, many artifacts, many samples",UPN2_012,4,106196337,T,A,missense_variant(MODERATE|MISSENSE|gTc/gAc|p.Val1557Asp/c.4670T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4516,58,4599,"0,0126114373",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,48",Neutral,0,Damaging,"32,67","19,16"
"low bq, low freq, many artifacts, many samples",UPN2_077,4,106196337,T,A,missense_variant(MODERATE|MISSENSE|gTc/gAc|p.Val1557Asp/c.4670T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1371,22,1400,"0,0157142857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,48",Neutral,0,Damaging,"31,73","25,23"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106196337,T,A,missense_variant(MODERATE|MISSENSE|gTc/gAc|p.Val1557Asp/c.4670T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2629,41,2696,"0,0152077151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,48",Neutral,0,Damaging,"31,94","17,66"
"low bq, low freq, many artifacts",UPN2_087,4,106196337,T,A,missense_variant(MODERATE|MISSENSE|gTc/gAc|p.Val1557Asp/c.4670T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2129,28,2178,"0,012855831",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,48",Neutral,0,Damaging,"31,82","21,25"
"low freq, many artifacts",UPN2_093,4,106196337,T,C,missense_variant(MODERATE|MISSENSE|gTc/gCc|p.Val1557Ala/c.4670T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1770,21,1801,"0,0116601888",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,003",Damaging,"33,31","32,9"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106196340,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn1558Thr/c.4673A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1836,27,1868,"0,0144539615",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,17,Damaging,"30,51","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106196340,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn1558Thr/c.4673A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2653,28,2696,"0,0103857567",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,17,Damaging,"30,63","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_082,4,106196340,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn1558Thr/c.4673A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1480,21,1511,"0,0138980807",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,17,Damaging,"30,17",14
"low bq, low freq, many artifacts, many samples",UPN2_083,4,106196340,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn1558Thr/c.4673A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2125,25,2167,"0,0115366867",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,17,Damaging,"30,31","16,2"
"low bq, low freq, many artifacts, many samples",UPN2_084,4,106196340,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn1558Thr/c.4673A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1505,24,1535,"0,0156351792",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,17,Damaging,"30,69","17,33"
"low bq, low freq, many artifacts",UPN2_087,4,106196340,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn1558Thr/c.4673A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2127,36,2179,"0,0165213401",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,17,Damaging,"30,98","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_001,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3226,47,3287,"0,0142987527",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"32,04","14,15"
"low bq, low freq, many artifacts, many samples",UPN2_014,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),8125,111,8261,"0,0134366299",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"32,9","15,65"
"low bq, low freq, many artifacts, many samples",UPN2_017,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4683,49,4763,"0,0102876338",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"33,16","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_019,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6762,70,6859,"0,0102055693",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"32,88","16,27"
"low bq, low freq, many artifacts, many samples",UPN2_020,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5173,67,5257,"0,0127449115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"32,89","19,78"
"low bq, low freq, many artifacts, many samples",UPN2_021,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6204,68,6289,"0,0108125298",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"32,99","16,78"
"low bq, low freq, many artifacts, many samples",UPN2_002,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4326,51,4399,"0,011593544",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"32,25","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_022,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7507,93,7627,"0,012193523",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"33,15","18,54"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),14518,188,14797,"0,0127052781",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"32,56","16,89"
"low bq, low freq, many artifacts, many samples",UPN2_028,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4273,46,4333,"0,0106162012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"32,93","16,59"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9627,109,9778,"0,0111474739",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"32,5","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_044,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2359,31,2401,"0,012911287",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"32,62","17,55"
"low bq, low freq, many artifacts, many samples",UPN2_030,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9274,111,9422,"0,0117809382",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"33,06","15,57"
"low bq, low freq, many artifacts, many samples",UPN2_045,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),12386,150,12629,"0,011877425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"32,6","16,04"
"low bq, low freq, many artifacts, many samples",UPN2_046,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9404,116,9568,"0,0121237458",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"32,53","15,71"
"low bq, low freq, many artifacts, many samples",UPN2_034,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1965,20,1995,"0,0100250627",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"32,97","16,1"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),15813,205,16095,"0,0127368748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"32,51","15,41"
"low bq, low freq, many artifacts, many samples",UPN2_048,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3645,45,3708,"0,0121359223",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"32,43","16,73"
"low bq, low freq, many artifacts, many samples",UPN2_035,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),13055,136,13235,"0,0102757839",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"33,06","16,35"
"low bq, low freq, many artifacts, many samples",UPN2_036,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),8602,93,8726,"0,0106578043",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"32,9","15,85"
"low bq, low freq, many artifacts, many samples",UPN2_006,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5128,92,5241,"0,0175539019",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"32,33","17,53"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6223,96,6344,"0,0151324086",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"32,64","15,98"
"low bq, low freq, many artifacts, many samples",UPN2_050,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9572,124,9764,"0,0126997132",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"32,51","16,1"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9137,153,9337,"0,0163864196",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"32,48","17,56"
"low bq, low freq, many artifacts, many samples",UPN2_052,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7837,100,7971,"0,0125454774",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"32,57","15,64"
"low bq, low freq, many artifacts, many samples",UPN2_039,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),22497,250,22831,"0,0109500241",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"33,01","16,62"
"low bq, low freq, many artifacts, many samples",UPN2_053,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),11731,173,11954,"0,0144721432",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"32,43","17,77"
"low bq, low freq, many artifacts, many samples",UPN2_054,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6366,83,6491,"0,0127869358",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"32,38","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_007,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),10095,163,10309,"0,0158114269",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"32,24","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_008,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),17294,274,17658,"0,0155170461",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"32,2","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_009,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),13420,220,13708,"0,0160490225",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"32,29","15,98"
"low bq, low freq, many artifacts, many samples",UPN2_010,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5422,77,5528,"0,0139290883",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"32,19","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_011,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7476,126,7630,"0,0165137615",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"32,31","16,07"
"low bq, low freq, many artifacts, many samples",UPN2_055,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),14760,194,15025,"0,0129118136",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"32,56","16,24"
"low bq, low freq, many artifacts, many samples",UPN2_056,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2459,26,2493,"0,0104292018",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"32,64","19,19"
"low bq, low freq, many artifacts, many samples",UPN2_057,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6685,97,6821,"0,0142207887",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"32,46","16,22"
"low bq, low freq, many artifacts, many samples",UPN2_058,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6311,76,6416,"0,0118453865",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"32,62","15,88"
"low bq, low freq, many artifacts, many samples",UPN2_059,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2028,21,2060,"0,0101941748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"32,28",14
"low bq, low freq, many artifacts, many samples",UPN2_012,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4501,76,4598,"0,0165289256",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"32,35","16,7"
"low bq, low freq, many artifacts, many samples",UPN2_040,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),23348,254,23710,"0,0107127794",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"32,96","16,41"
"low bq, low freq, many artifacts, many samples",UPN2_013,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2377,31,2420,"0,0128099174",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"32,14","17,06"
"low bq, low freq, many artifacts, many samples",UPN2_071,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1462,24,1495,"0,0160535117",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"31,83","18,79"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1833,26,1866,"0,0139335477",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"31,99","17,04"
"low bq, low freq, many artifacts, many samples",UPN2_075,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1674,28,1710,"0,016374269",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"32,26","19,36"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2642,39,2692,"0,01448737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"32,04","16,51"
"low bq, low freq, many artifacts, many samples",UPN2_082,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1480,20,1510,"0,0132450331",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"31,8",14
"low bq, low freq, many artifacts, many samples",UPN2_083,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2126,31,2165,"0,0143187067",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,32,14
"low bq, low freq, many artifacts",UPN2_087,4,106196342,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1559Thr/c.4675T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2125,37,2178,"0,0169880624",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,283,Tolerated,"31,91","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_001,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3234,42,3283,"0,012793177",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"31,82","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_016,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6219,78,6321,"0,0123398196",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"31,54","17,08"
"low bq, low freq, many artifacts, many samples",UPN2_020,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5181,59,5249,"0,0112402362",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"31,7","15,76"
"low bq, low freq, many artifacts, many samples",UPN2_002,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4317,58,4394,"0,0131998179",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"32,03","15,41"
"low bq, low freq, many artifacts, many samples",UPN2_022,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7532,81,7625,"0,0106229508",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"31,9","16,33"
"low bq, low freq, many artifacts, many samples",UPN2_024,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3926,53,3990,"0,013283208",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"31,5","16,4"
"low bq, low freq, many artifacts, many samples",UPN2_025,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),11129,114,11282,"0,0101045914",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"31,77","17,13"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),14504,208,14778,"0,0140749763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"31,05","17,27"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9585,140,9765,"0,0143369176",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"31,01","15,89"
"low bq, low freq, many artifacts, many samples",UPN2_044,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2355,29,2400,"0,0120833333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"31,12","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_029,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6418,74,6510,"0,0113671275",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"31,74","15,58"
"low bq, low freq, many artifacts, many samples",UPN2_031,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5916,66,5994,"0,011011011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"31,77","16,47"
"low bq, low freq, many artifacts, many samples",UPN2_045,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),12385,152,12614,"0,0120501031",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"31,1","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_032,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2119,32,2156,"0,0148423006",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"31,73","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_046,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9417,113,9558,"0,011822557",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"30,98","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_033,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6358,82,6455,"0,0127033308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"31,62","15,78"
"low bq, low freq, many artifacts, many samples",UPN2_034,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1958,20,1993,"0,0100351229",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"31,56","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),15789,205,16075,"0,0127527216",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"31,07","16,12"
"low bq, low freq, many artifacts, many samples",UPN2_048,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3626,53,3700,"0,0143243243",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"31,18","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_006,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5153,73,5235,"0,0139446036",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"32,02","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6206,99,6337,"0,0156225343",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"31,24","16,75"
"low bq, low freq, many artifacts, many samples",UPN2_050,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9565,129,9745,"0,0132375577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"30,89","16,18"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9107,158,9323,"0,0169473345",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"30,94","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_052,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7782,108,7965,"0,013559322",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"31,19","15,9"
"low bq, low freq, many artifacts, many samples",UPN2_038,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),14427,149,14613,"0,0101964005",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"31,77","16,17"
"low bq, low freq, many artifacts, many samples",UPN2_053,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),11695,162,11934,"0,0135746606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"31,06","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_054,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6362,74,6477,"0,0114250425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"31,05","16,45"
"low bq, low freq, many artifacts, many samples",UPN2_007,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),10125,144,10298,"0,0139832977",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"31,91","18,43"
"low bq, low freq, many artifacts, many samples",UPN2_008,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),17379,214,17645,"0,0121280816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"31,91","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_009,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),13471,167,13680,"0,0122076023",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"31,94","15,25"
"low bq, low freq, many artifacts, many samples",UPN2_011,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7513,81,7624,"0,0106243442",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"31,93","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_055,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),14723,211,15011,"0,0140563587",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"31,07","16,3"
"low bq, low freq, many artifacts, many samples",UPN2_056,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2428,28,2490,"0,0112449799",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"30,92",14
"low bq, low freq, many artifacts, many samples",UPN2_057,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6672,97,6813,"0,0142374872",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"31,15","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_058,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6306,69,6411,"0,0107627515",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"31,15","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_059,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2025,28,2060,"0,013592233",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"31,19","16,36"
"low bq, low freq, many artifacts, many samples",UPN2_012,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4516,67,4597,"0,0145747226",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"31,82","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_013,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2372,29,2417,"0,0119983451",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"31,76","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_069,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1517,20,1547,"0,0129282482",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"30,97",14
"low bq, low freq, many artifacts, many samples",UPN2_078,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1444,20,1476,"0,0135501355",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"31,29","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2644,31,2686,"0,0115413254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"31,09",14
"low bq, low freq, many artifacts, many samples",UPN2_082,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1478,22,1511,"0,0145598941",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"31,17",14
"low bq, low freq, many artifacts, many samples",UPN2_084,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1501,21,1531,"0,0137165251",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"30,79","14,86"
"low bq, low freq, many artifacts",UPN2_087,4,106196345,T,A,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr1560Asn/c.4678T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2131,37,2176,"0,0170036765",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,3,Damaging,"30,91","15,19"
"low freq, many artifacts",UPN2_056,4,106196345,T,C,missense_variant(MODERATE|MISSENSE|Tat/Cat|p.Tyr1560His/c.4678T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2428,25,2490,"0,0100401606",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,58",Deleterious,"0,199",Tolerated,"30,92","33,4"
"low bq, many samples",UPN2_001,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3193,75,3283,"0,0228449589",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,52","15,53"
"low bq, low freq, many artifacts, many samples",UPN2_014,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),8104,121,8259,"0,0146506841",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,8","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_015,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),12113,167,12342,"0,0135310322",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,82","15,81"
"low bq, low freq, many artifacts, many samples",UPN2_016,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6185,99,6321,"0,0156620788",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,67","15,6"
"low bq, low freq, many artifacts, many samples",UPN2_017,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4677,70,4759,"0,0147089725",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,87","16,83"
"low bq, low freq, many artifacts, many samples",UPN2_018,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6253,78,6347,"0,0122892705",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,6","15,71"
"low bq, low freq, many artifacts, many samples",UPN2_019,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6705,116,6853,"0,0169268933",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,68","16,33"
"low bq, low freq, many artifacts, many samples",UPN2_020,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5136,87,5249,"0,0165745856",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,8","16,06"
"low bq, low freq, many artifacts, many samples",UPN2_021,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6169,92,6286,"0,0146356984",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,79","15,61"
"low bq, low freq, many artifacts, many samples",UPN2_002,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4289,82,4393,"0,0186660596",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,55","16,16"
"low bq, low freq, many artifacts, many samples",UPN2_022,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7485,112,7623,"0,0146923783",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,95","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_023,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7489,107,7625,"0,0140327869",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,83","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_041,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1146,20,1179,"0,0169635284",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,09","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_024,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3919,56,3990,"0,0140350877",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,77","15,48"
"low bq, low freq, many artifacts, many samples",UPN2_025,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),11062,169,11281,"0,0149809414",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,01","16,69"
"low bq, low freq, many artifacts, many samples",UPN2_026,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9774,118,9924,"0,0118903668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,81","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_027,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),8173,104,8317,"0,0125045088",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,73","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),14381,304,14771,"0,0205808679",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,72","15,82"
"low bq, low freq, many artifacts, many samples",UPN2_028,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4245,62,4331,"0,0143154006",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,84","16,19"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9511,191,9764,"0,0195616551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,72","16,02"
"low bq, low freq, many artifacts, many samples",UPN2_044,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2323,52,2400,"0,0216666667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,83","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_029,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6392,82,6510,"0,0125960061",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,78","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_030,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9264,124,9414,"0,0131718717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,8","16,42"
"low bq, low freq, many artifacts, many samples",UPN2_031,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5887,77,5994,"0,0128461795",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,84","16,4"
"low bq, low freq, many artifacts, many samples",UPN2_045,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),12296,230,12613,"0,0182351542",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,78","16,29"
"low bq, low freq, many artifacts, many samples",UPN2_032,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2120,25,2156,"0,0115955473",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,84","20,36"
"low bq, low freq, many artifacts, many samples",UPN2_046,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9310,180,9556,"0,0188363332",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,57","15,46"
"low bq, low freq, many artifacts, many samples",UPN2_033,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6329,101,6454,"0,0156492098",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,69","17,32"
"low bq, low freq, many artifacts, many samples",UPN2_034,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1953,36,1993,"0,0180632213",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,85","16,67"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),15646,347,16069,"0,0215943743",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,71","15,76"
"low bq, low freq, many artifacts, many samples",UPN2_048,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3604,68,3699,"0,0183833469",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,81","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_035,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),12949,197,13221,"0,014900537",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,99","16,34"
"low bq, low freq, many artifacts, many samples",UPN2_036,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),8549,142,8719,"0,0162862714",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,89","19,53"
"low bq, low freq, many artifacts, many samples",UPN2_006,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5104,106,5234,"0,0202521972",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,55","15,59"
"low bq, many samples",UPN2_049,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6134,147,6336,"0,0232007576",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,59","17,48"
"low bq, low freq, many artifacts, many samples",UPN2_050,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9515,184,9742,"0,0188872921",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,53","15,55"
"low bq, low freq, many artifacts, many samples",UPN2_037,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),10574,151,10761,"0,0140321531",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,94","15,02"
"low bq, many samples",UPN2_051,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9049,224,9323,"0,0240266009",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,45","15,68"
"low bq, low freq, many artifacts, many samples",UPN2_052,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7741,165,7964,"0,020718232",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,69","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_038,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),14340,215,14612,"0,0147139338",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,86","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_039,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),22396,329,22811,"0,0144228662",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,87","17,28"
"low bq, low freq, many artifacts, many samples",UPN2_053,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),11605,262,11931,"0,021959601",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,47","15,43"
"low bq, many samples",UPN2_054,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6297,145,6477,"0,0223869075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,43","15,73"
"low bq, low freq, many artifacts, many samples",UPN2_007,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),10060,206,10298,"0,0200038842",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,56","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_008,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),17235,339,17643,"0,0192144193",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,67","16,96"
"low bq, low freq, many artifacts, many samples",UPN2_009,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),13379,243,13675,"0,0177696527",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,61",15
"low bq, low freq, many artifacts, many samples",UPN2_010,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5379,117,5517,"0,0212071778",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,5","16,07"
"low bq, low freq, many artifacts, many samples",UPN2_011,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7468,122,7623,"0,0160041978",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,48","15,57"
"low bq, many samples",UPN2_055,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),14536,354,15008,"0,02358742",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,6","18,25"
"low bq, low freq, many artifacts, many samples",UPN2_056,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2432,47,2489,"0,0188830856",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,75","16,43"
"low bq, low freq, many artifacts, many samples",UPN2_090,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4743,52,4808,"0,0108153078",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,6","15,96"
"low bq, many samples",UPN2_057,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6621,154,6813,"0,0226038456",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,51","15,76"
"low bq, low freq, many artifacts, many samples",UPN2_058,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6246,133,6410,"0,02074883",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,7","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_059,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2017,30,2060,"0,0145631068",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,66","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_012,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4492,91,4595,"0,0198041349",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,45","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_040,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),23266,334,23693,"0,0140969907",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,83","15,78"
"low bq, low freq, many artifacts, many samples",UPN2_013,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2368,37,2417,"0,0153082333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,49","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_064,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1355,20,1385,"0,0144404332",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,57",14
"low bq, low freq, many artifacts, many samples",UPN2_065,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1105,23,1142,"0,0201401051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,2","15,13"
"low bq, many samples",UPN2_067,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),987,31,1022,"0,030332681",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,22",16
"low bq, many samples",UPN2_068,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),852,23,879,"0,0261660978",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,97",14
"low bq, low freq, many artifacts, many samples",UPN2_069,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1514,20,1547,"0,0129282482",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,24",14
"low bq, low freq, many artifacts, many samples",UPN2_071,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1452,25,1494,"0,0167336011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,14","16,12"
"low bq, many samples",UPN2_072,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1468,37,1517,"0,0243902439",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,24","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1816,34,1865,"0,018230563",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,22","14,38"
"low bq, many samples",UPN2_074,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),913,26,952,"0,0273109244",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,43","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_075,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1676,22,1708,"0,0128805621",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,59",14
"low bq, low freq, many artifacts, many samples",UPN2_076,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1194,26,1229,"0,0211554109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,37","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_077,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1358,20,1398,"0,0143061516",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,24","15,3"
"low bq, low freq, many artifacts, many samples",UPN2_079,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1081,23,1118,"0,0205724508",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,97",14
"low bq, low freq, many artifacts, many samples",UPN2_080,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1248,23,1278,"0,0179968701",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,43","15,52"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2607,50,2686,"0,018615041",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,39","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_082,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1467,27,1511,"0,017868961",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,97","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_083,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2092,46,2161,"0,0212864415",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,69","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_085,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1317,25,1345,"0,0185873606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,06",14
"low bq, low freq, many artifacts, many samples",UPN2_087,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2123,43,2176,"0,0197610294",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,25","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_088,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1312,23,1342,"0,0171385991",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,26","17,26"
"low bq, low freq, many artifacts, many samples",UPN2_094,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5587,65,5674,"0,0114557631",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,68","15,49"
"low bq, low freq, many artifacts, many samples",UPN2_096,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6088,62,6177,"0,0100372349",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,56","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_097,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7000,75,7103,"0,0105589188",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,6","16,69"
"low bq, low freq, many artifacts, many samples",UPN2_099,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2872,38,2922,"0,0130047912",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,31","15,53"
"low bq, low freq, many artifacts, many samples",UPN2_100,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5404,67,5492,"0,012199563",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,62","15,84"
"low bq, low freq, many artifacts, many samples",UPN2_101,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3509,45,3565,"0,0126227209",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,5",14
"low bq, low freq, many artifacts",UPN2_108,4,106196347,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr1560*/c.4680T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9759,110,9909,"0,0111010193",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,69","15,6"
"low bq, low freq, many artifacts, many samples",UPN2_001,4,106196348,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1561Thr/c.4681T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3233,39,3283,"0,0118793786",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,59",Neutral,11,Damaging,"33,36","19,21"
"low bq, low freq, many artifacts",UPN2_041,4,106196348,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1561Thr/c.4681T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1143,31,1179,"0,026293469",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,59",Neutral,"0,011",Damaging,"32,38","26,52"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106196348,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1561Thr/c.4681T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),14555,168,14767,"0,0113767184",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,59",Neutral,11,Damaging,"32,59","17,8"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106196348,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1561Thr/c.4681T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9601,133,9761,"0,0136256531",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,59",Neutral,11,Damaging,"32,62","15,82"
"low bq, low freq, many artifacts, many samples",UPN2_045,4,106196348,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1561Thr/c.4681T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),12420,147,12609,"0,0116583393",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,59",Neutral,11,Damaging,"32,6","18,29"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106196348,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1561Thr/c.4681T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),15785,191,16066,"0,0118884601",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,59",Neutral,11,Damaging,"32,46","17,02"
"low bq, low freq, many artifacts, many samples",UPN2_006,4,106196348,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1561Thr/c.4681T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5128,56,5231,"0,0107054101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,59",Neutral,11,Damaging,"33,38","16,41"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106196348,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1561Thr/c.4681T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6247,67,6331,"0,0105828463",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,59",Neutral,11,Damaging,"32,58","16,16"
"low bq, low freq, many artifacts, many samples",UPN2_050,4,106196348,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1561Thr/c.4681T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9609,107,9740,"0,0109856263",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,59",Neutral,11,Damaging,"32,51","15,69"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106196348,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1561Thr/c.4681T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9160,122,9320,"0,0130901288",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,59",Neutral,11,Damaging,"32,51","15,66"
"low bq, low freq, many artifacts, many samples",UPN2_052,4,106196348,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1561Thr/c.4681T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7855,89,7962,"0,011178096",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,59",Neutral,11,Damaging,"32,57","18,73"
"low bq, low freq, many artifacts, many samples",UPN2_053,4,106196348,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1561Thr/c.4681T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),11730,155,11929,"0,0129935451",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,59",Neutral,11,Damaging,"32,57","15,55"
"low bq, low freq, many artifacts, many samples",UPN2_054,4,106196348,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1561Thr/c.4681T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6387,65,6476,"0,0100370599",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,59",Neutral,11,Damaging,"32,52",16
"low bq, low freq, many artifacts, many samples",UPN2_007,4,106196348,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1561Thr/c.4681T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),10141,117,10296,"0,0113636364",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,59",Neutral,11,Damaging,"33,22","20,09"
"low bq, low freq, many artifacts, many samples",UPN2_055,4,106196348,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1561Thr/c.4681T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),14787,166,15006,"0,0110622418",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,59",Neutral,11,Damaging,"32,51","16,93"
"low bq, low freq, many artifacts, many samples",UPN2_057,4,106196348,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1561Thr/c.4681T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6706,85,6812,"0,01247798",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,59",Neutral,11,Damaging,"32,57","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_058,4,106196348,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1561Thr/c.4681T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6332,66,6408,"0,0102996255",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,59",Neutral,11,Damaging,"32,52","16,14"
"low bq, low freq, many artifacts",UPN2_059,4,106196348,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1561Thr/c.4681T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2029,21,2058,"0,0102040816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,59",Neutral,11,Damaging,"32,66","17,14"
"low bq, low freq, many artifacts, many samples",UPN2_001,4,106196354,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1563Thr/c.4687T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3224,35,3280,"0,0106707317",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,104,Tolerated,"33,02","19,17"
"low bq, low freq, many artifacts, many samples",UPN2_044,4,106196354,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1563Thr/c.4687T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2365,25,2397,"0,0104297038",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,104,Tolerated,"32,22","17,64"
"low bq, low freq, many artifacts, many samples",UPN2_046,4,106196354,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1563Thr/c.4687T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9387,127,9544,"0,0133067896",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,104,Tolerated,"32,22","23,84"
"low bq, low freq, many artifacts, many samples",UPN2_050,4,106196354,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1563Thr/c.4687T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9567,119,9729,"0,0122314729",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,104,Tolerated,"32,11","22,23"
"low bq, low freq, many artifacts, many samples",UPN2_052,4,106196354,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1563Thr/c.4687T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7833,88,7958,"0,0110580548",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,104,Tolerated,"32,25","18,17"
"low bq, low freq, many artifacts, many samples",UPN2_053,4,106196354,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1563Thr/c.4687T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),11738,129,11919,"0,0108230556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,104,Tolerated,"32,21","17,59"
"low bq, low freq, many artifacts, many samples",UPN2_054,4,106196354,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1563Thr/c.4687T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6366,68,6465,"0,0105181748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,104,Tolerated,"32,18","19,22"
"low bq, low freq, many artifacts, many samples",UPN2_056,4,106196354,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1563Thr/c.4687T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2454,27,2485,"0,0108651911",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,104,Tolerated,"32,2","20,63"
"low bq, low freq, many artifacts, many samples",UPN2_057,4,106196354,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1563Thr/c.4687T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6709,71,6799,"0,0104427122",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,104,Tolerated,"32,22","20,31"
"low bq, low freq, many artifacts, many samples",UPN2_012,4,106196354,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1563Thr/c.4687T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4523,46,4584,"0,010034904",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,104,Tolerated,"32,99","19,26"
"low bq, low freq, many artifacts",UPN2_087,4,106196354,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser1563Thr/c.4687T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2139,26,2173,"0,0119650253",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,104,Tolerated,"32,01","14,69"
"low bq, low freq, many artifacts",UPN2_084,4,106196357,G,C,missense_variant(MODERATE|MISSENSE|Gga/Cga|p.Gly1564Arg/c.4690G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1496,20,1529,"0,0130804447",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,1,Damaging,"30,18","14,65"
"inspected, many artifacts",UPN2_060,4,106196358,G,A,missense_variant(MODERATE|MISSENSE|gGa/gAa|p.Gly1564Glu/c.4691G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1466,31,1514,"0,0204755614",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,32",Deleterious,"0,001",Damaging,"30,97","31,61"
"low bq, low freq, many artifacts, many samples",UPN2_059,4,106196358,G,C,missense_variant(MODERATE|MISSENSE|gGa/gCa|p.Gly1564Ala/c.4691G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2023,25,2055,"0,0121654501",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,214,Tolerated,"30,92","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106196358,G,C,missense_variant(MODERATE|MISSENSE|gGa/gCa|p.Gly1564Ala/c.4691G>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2636,36,2681,"0,0134278254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,214,Tolerated,"30,85","15,58"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106196360,T,A,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser1565Thr/c.4693T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9158,104,9302,"0,0111803913",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,32",Neutral,24,Damaging,"31,96","16,91"
"low bq, low freq, many artifacts, many samples",UPN2_053,4,106196360,T,A,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser1565Thr/c.4693T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),11721,125,11913,"0,010492739",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,32",Neutral,24,Damaging,"31,94","18,88"
"low bq, low freq, many artifacts, many samples",UPN2_011,4,106196360,T,A,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser1565Thr/c.4693T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7499,78,7607,"0,0102537137",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,32",Neutral,24,Damaging,"32,61","17,06"
"low bq, low freq, many artifacts",UPN2_013,4,106196360,T,A,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser1565Thr/c.4693T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2377,26,2410,"0,0107883817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,32",Neutral,24,Damaging,"32,57","17,04"
"low bq, low freq, many artifacts",UPN2_082,4,106196361,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser1565Tyr/c.4694C>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1478,22,1508,"0,0145888594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,9",Deleterious,3,Damaging,"30,72","18,14"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106196363,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1566Pro/c.4696A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),14505,151,14736,"0,0102470141",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,294,Tolerated,"30,36","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_044,4,106196363,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1566Pro/c.4696A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2351,25,2393,"0,0104471375",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,294,Tolerated,"30,09","17,52"
"low bq, low freq, many artifacts, many samples",UPN2_045,4,106196363,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1566Pro/c.4696A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),12341,143,12585,"0,0113627334",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,294,Tolerated,"30,33","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106196363,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1566Pro/c.4696A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),15707,176,16015,"0,0109896972",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,294,Tolerated,"30,38","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106196363,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1566Pro/c.4696A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6216,65,6312,"0,0102978454",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,294,Tolerated,"30,44","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_050,4,106196363,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1566Pro/c.4696A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),9532,110,9713,"0,0113250283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,294,Tolerated,"30,27","15,99"
"low bq, low freq, many artifacts, many samples",UPN2_052,4,106196363,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1566Pro/c.4696A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),7810,86,7946,"0,0108230556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,294,Tolerated,"30,39","15,65"
"low bq, low freq, many artifacts, many samples",UPN2_054,4,106196363,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1566Pro/c.4696A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6353,73,6460,"0,0113003096",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,294,Tolerated,"30,29","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_055,4,106196363,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1566Pro/c.4696A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),14702,152,14959,"0,010161107",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,294,Tolerated,"30,39","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_056,4,106196363,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1566Pro/c.4696A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2428,32,2478,"0,01291364",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,294,Tolerated,"30,36","19,56"
"low bq, low freq, many artifacts, many samples",UPN2_057,4,106196363,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1566Pro/c.4696A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6667,69,6789,"0,0101634998",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,294,Tolerated,"30,35","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_058,4,106196363,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1566Pro/c.4696A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6295,67,6398,"0,0104720225",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,294,Tolerated,"30,46","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_059,4,106196363,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1566Pro/c.4696A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2008,37,2052,"0,0180311891",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,294,Tolerated,"29,67","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_060,4,106196363,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1566Pro/c.4696A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1473,28,1511,"0,0185307743",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,294,Tolerated,"29,87","14,93"
"low bq, many samples",UPN2_063,4,106196363,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1566Pro/c.4696A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),958,22,988,"0,0222672065",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,294,Tolerated,"29,75","14,91"
"low bq, many samples",UPN2_064,4,106196363,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1566Pro/c.4696A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1336,35,1382,"0,0253256151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,294,Tolerated,"30,55","14,57"
"low bq, many samples",UPN2_069,4,106196363,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1566Pro/c.4696A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1501,34,1542,"0,0220492866",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,294,Tolerated,"29,94","15,74"
"low bq, many samples",UPN2_071,4,106196363,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1566Pro/c.4696A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1450,33,1486,"0,0222072678",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,294,Tolerated,"29,82","14,21"
"low bq, many samples",UPN2_072,4,106196363,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1566Pro/c.4696A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1468,38,1510,"0,0251655629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,294,Tolerated,"29,85","16,05"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106196363,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1566Pro/c.4696A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1817,33,1856,"0,0177801724",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,294,Tolerated,"29,61","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_075,4,106196363,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1566Pro/c.4696A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1663,31,1703,"0,0182031709",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,294,Tolerated,"30,07","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_076,4,106196363,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1566Pro/c.4696A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1198,24,1227,"0,0195599022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,294,Tolerated,"29,72","14,54"
"low bq, many samples",UPN2_077,4,106196363,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1566Pro/c.4696A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1345,47,1395,"0,0336917563",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,294,Tolerated,"29,6","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_078,4,106196363,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1566Pro/c.4696A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1447,23,1473,"0,0156143924",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,294,Tolerated,"29,82","14,87"
"low bq, many samples",UPN2_079,4,106196363,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1566Pro/c.4696A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1082,26,1112,"0,023381295",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,294,Tolerated,"30,24",14
"low bq, low freq, many artifacts, many samples",UPN2_080,4,106196363,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1566Pro/c.4696A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1237,28,1274,"0,021978022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,294,Tolerated,"29,68",14
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106196363,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1566Pro/c.4696A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2621,43,2678,"0,0160567588",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,294,Tolerated,"29,91","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_082,4,106196363,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1566Pro/c.4696A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1472,27,1508,"0,0179045093",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,294,Tolerated,"29,78","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_083,4,106196363,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1566Pro/c.4696A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2101,37,2154,"0,0171773445",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,294,Tolerated,"29,56",14
"low bq, low freq, many artifacts, many samples",UPN2_084,4,106196363,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1566Pro/c.4696A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1500,27,1527,"0,0176817289",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,294,Tolerated,"30,01",14
"low bq, low freq, many artifacts, many samples",UPN2_085,4,106196363,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1566Pro/c.4696A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1312,26,1343,"0,0193596426",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,294,Tolerated,"29,89","15,5"
"low bq, low freq, many artifacts, many samples",UPN2_086,4,106196363,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1566Pro/c.4696A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),975,21,999,"0,021021021",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,294,Tolerated,"29,74","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_087,4,106196363,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1566Pro/c.4696A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2123,39,2170,"0,0179723502",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,294,Tolerated,"29,78","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_088,4,106196363,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1566Pro/c.4696A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1302,24,1337,"0,0179506358",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,294,Tolerated,"29,81","14,54"
"low bq, low freq, many artifacts",UPN2_102,4,106196363,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1566Pro/c.4696A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4001,44,4070,"0,0108108108",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,294,Tolerated,"30,61","14,48"
"low freq, many artifacts",UPN2_048,4,106196366,A,G,missense_variant(MODERATE|MISSENSE|Aat/Gat|p.Asn1567Asp/c.4699A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),3619,37,3683,"0,010046158",0,0,0,0,1,0,0,0,1,NO,NO,COSM5191274,large_intestine,1,NO,NO,NO,NO,NO,NO,"-1,3",Neutral,25,Damaging,"32,15","32,11"
"low bq, low freq, many artifacts, many samples",UPN2_059,4,106196367,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn1567Thr/c.4700A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2017,30,2051,"0,0146270112",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,13",Neutral,6,Damaging,"30,41","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_060,4,106196367,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn1567Thr/c.4700A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1472,20,1510,"0,0132450331",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,13",Neutral,6,Damaging,"29,55",14
"low bq, many samples",UPN2_067,4,106196367,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn1567Thr/c.4700A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),993,23,1018,"0,0225933202",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,13",Neutral,6,Damaging,"29,7","16,52"
"low bq, low freq, many artifacts, many samples",UPN2_069,4,106196367,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn1567Thr/c.4700A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1513,23,1541,"0,0149253731",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,13",Neutral,6,Damaging,"30,12",14
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106196367,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn1567Thr/c.4700A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1468,30,1506,"0,0199203187",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,13",Neutral,6,Damaging,"29,52","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106196367,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn1567Thr/c.4700A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1818,32,1855,"0,0172506739",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,13",Neutral,6,Damaging,"29,92","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_075,4,106196367,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn1567Thr/c.4700A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1674,26,1704,"0,015258216",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,13",Neutral,6,Damaging,"30,23","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_076,4,106196367,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn1567Thr/c.4700A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1199,20,1225,"0,0163265306",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,13",Neutral,6,Damaging,"29,74",14
"low bq, low freq, many artifacts, many samples",UPN2_077,4,106196367,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn1567Thr/c.4700A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1358,26,1393,"0,0186647523",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,13",Neutral,6,Damaging,"29,48","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_078,4,106196367,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn1567Thr/c.4700A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1441,25,1473,"0,0169721656",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,13",Neutral,6,Damaging,"29,76","15,52"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106196367,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn1567Thr/c.4700A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2637,35,2679,"0,0130645763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,13",Neutral,6,Damaging,"29,99","16,66"
"low bq, low freq, many artifacts, many samples",UPN2_082,4,106196367,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn1567Thr/c.4700A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1475,26,1506,"0,0172642762",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,13",Neutral,6,Damaging,"29,77","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_083,4,106196367,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn1567Thr/c.4700A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2119,27,2152,"0,0125464684",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,13",Neutral,6,Damaging,"29,97","15,3"
"low bq, low freq, many artifacts, many samples",UPN2_084,4,106196367,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn1567Thr/c.4700A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1489,31,1525,"0,0203278689",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,13",Neutral,6,Damaging,"29,91","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_085,4,106196367,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn1567Thr/c.4700A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1315,25,1343,"0,018615041",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,13",Neutral,6,Damaging,"29,99","15,52"
"low bq, low freq, many artifacts, many samples",UPN2_087,4,106196367,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn1567Thr/c.4700A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2111,47,2167,"0,0216889709",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,13",Neutral,6,Damaging,"29,86","14,3"
"low bq, low freq, many artifacts",UPN2_088,4,106196367,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn1567Thr/c.4700A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1310,21,1335,"0,0157303371",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,13",Neutral,6,Damaging,"29,97",14
"low bq, low freq, many artifacts, many samples",UPN2_001,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3202,51,3282,"0,0155393053",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,47","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_014,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),8089,119,8254,"0,0144172522",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,84","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_015,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),12120,158,12323,"0,0128215532",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"32,02","15,87"
"low bq, low freq, many artifacts, many samples",UPN2_016,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6186,90,6319,"0,0142427599",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,82","16,04"
"low bq, low freq, many artifacts, many samples",UPN2_017,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4665,75,4762,"0,015749685",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"32,07",15
"low bq, low freq, many artifacts, many samples",UPN2_018,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6244,76,6351,"0,0119666194",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,83","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_019,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6734,82,6854,"0,0119638167",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,91","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_020,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5155,65,5239,"0,0124069479",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,83","16,23"
"low bq, low freq, many artifacts, many samples",UPN2_021,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6149,88,6318,"0,0139284584",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,97","16,59"
"low bq, low freq, many artifacts, many samples",UPN2_002,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4289,80,4405,"0,0181611805",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,46","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_022,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7481,99,7621,"0,0129904212",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"32,1","16,67"
"low bq, low freq, many artifacts, many samples",UPN2_023,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7496,93,7645,"0,0121648136",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,85","15,3"
"low bq, low freq, many artifacts, many samples",UPN2_024,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3905,69,4006,"0,0172241638",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,85","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_025,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),11067,147,11264,"0,0130504261",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,97","16,52"
"low bq, low freq, many artifacts, many samples",UPN2_026,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9702,162,9943,"0,0162928694",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,96","16,09"
"low bq, low freq, many artifacts, many samples",UPN2_027,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),8178,98,8338,"0,0117534181",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,95","16,81"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),14377,261,14764,"0,017678136",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,23","16,81"
"low bq, low freq, many artifacts, many samples",UPN2_028,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4234,48,4324,"0,0111008326",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"32,01","18,5"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9496,183,9755,"0,0187596105",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,28","16,55"
"low bq, low freq, many artifacts, many samples",UPN2_044,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2332,44,2395,"0,0183716075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,43","17,32"
"low bq, low freq, many artifacts, many samples",UPN2_029,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6397,78,6551,"0,0119065791",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,95","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_030,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9213,125,9417,"0,0132738664",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"32,03","15,69"
"low bq, low freq, many artifacts, many samples",UPN2_031,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5865,80,5980,"0,0133779264",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,99","15,49"
"low bq, many samples",UPN2_005,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1117,32,1158,"0,0276338515",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,6","15,66"
"low bq, low freq, many artifacts, many samples",UPN2_045,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),12327,190,12640,"0,0150316456",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,39","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_046,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9280,178,9536,"0,0186661074",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,43","16,25"
"low bq, low freq, many artifacts, many samples",UPN2_033,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6308,107,6462,"0,0165583411",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"32,01","16,96"
"low bq, low freq, many artifacts, many samples",UPN2_034,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1953,30,1996,"0,0150300601",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,66","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),15636,268,16020,"0,0167290886",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,23","16,51"
"low bq, low freq, many artifacts, many samples",UPN2_048,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3564,56,3846,"0,0145605824",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,26","16,14"
"low bq, low freq, many artifacts, many samples",UPN2_035,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),13000,159,13258,"0,0119927591",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,97","15,99"
"low bq, low freq, many artifacts, many samples",UPN2_036,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),8577,105,8714,"0,0120495754",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,91","15,41"
"low bq, low freq, many artifacts, many samples",UPN2_006,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5070,91,5196,"0,0175134719",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,49","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6144,108,6297,"0,0171510243",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,35","16,51"
"low bq, low freq, many artifacts, many samples",UPN2_050,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9468,172,9695,"0,0177411037",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,23","16,23"
"low bq, low freq, many artifacts, many samples",UPN2_037,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),10553,130,10747,"0,012096399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"32,01","15,42"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9052,168,9305,"0,0180548092",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,3","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_052,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7738,136,7938,"0,017132779",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,43","15,46"
"low bq, low freq, many artifacts, many samples",UPN2_038,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),14397,180,14639,"0,0122959219",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,87","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_039,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),22444,287,22860,"0,0125546807",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,96","15,76"
"low bq, low freq, many artifacts, many samples",UPN2_053,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),11610,211,11924,"0,0176954042",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,24","15,45"
"low bq, low freq, many artifacts, many samples",UPN2_054,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6305,108,6493,"0,0166332974",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,19","15,7"
"low bq, low freq, many artifacts, many samples",UPN2_007,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9994,200,10316,"0,0193873594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,5","15,57"
"low bq, low freq, many artifacts, many samples",UPN2_008,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),17164,325,17622,"0,0184428555",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,52","17,42"
"low bq, low freq, many artifacts, many samples",UPN2_009,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),13349,237,13674,"0,0173321632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,55","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_010,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5389,95,5559,"0,0170894046",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,51","15,45"
"low bq, low freq, many artifacts, many samples",UPN2_011,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7483,135,7693,"0,0175484206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,52","16,1"
"low bq, low freq, many artifacts, many samples",UPN2_055,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),14569,280,14970,"0,0187040748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,23","16,16"
"low bq, low freq, many artifacts, many samples",UPN2_057,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6627,111,6766,"0,0164055572",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,22","15,68"
"low bq, low freq, many artifacts, many samples",UPN2_058,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6256,116,6388,"0,0181590482",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,46","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_059,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2025,38,2314,"0,0164217805",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"30,92","14,53"
"low bq, many samples",UPN2_012,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4436,117,4599,"0,0254403131",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,7","19,22"
"low bq, low freq, many artifacts, many samples",UPN2_060,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1512,20,1577,"0,0126823082",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"30,56","20,4"
"low bq, low freq, many artifacts, many samples",UPN2_040,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),23341,278,23735,"0,0117126606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,84","15,62"
"low bq, low freq, many artifacts, many samples",UPN2_013,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2358,37,2402,"0,0154038301",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"31,48","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_064,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1388,21,1456,"0,0144230769",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"30,97","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_065,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1165,20,1262,"0,0158478605",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"30,72","16,65"
"low bq, low freq, many artifacts, many samples",UPN2_067,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1009,22,1229,"0,0179007323",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"30,66","18,59"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1834,29,1925,"0,0150649351",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"30,52",14
"low bq, low freq, many artifacts, many samples",UPN2_074,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),940,22,1059,"0,0207743154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"30,57","15,82"
"low bq, low freq, many artifacts, many samples",UPN2_075,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1697,24,1756,"0,013667426",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"30,74","15,5"
"low bq, low freq, many artifacts, many samples",UPN2_077,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1372,21,1507,"0,0139349701",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"30,4","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_078,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1472,24,1569,"0,0152963671",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"30,9","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_079,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1091,22,1167,"0,0188517566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"30,74","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2672,45,2814,"0,0159914712",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"30,67","16,96"
"low bq, low freq, many artifacts, many samples",UPN2_083,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2115,31,2227,"0,0139200718",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"30,62","16,35"
"low bq, low freq, many artifacts, many samples",UPN2_085,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1346,20,1452,"0,0137741047",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"30,39","15,55"
"low bq, low freq, many artifacts",UPN2_087,4,106196368,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn1567Lys/c.4701T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2157,32,2354,"0,0135938828",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,7,Damaging,"30,57","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_016,4,106196372,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1569Asn/c.4705T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),10840,131,11005,"0,0119036801",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,43",Deleterious,11,Damaging,"31,32","18,56"
"low bq, low freq, many artifacts, many samples",UPN2_019,4,106196372,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1569Asn/c.4705T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),11997,125,12161,"0,01027876",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,43",Deleterious,11,Damaging,"31,4","18,98"
"low freq, many artifacts, many samples",UPN2_044,4,106196375,A,C,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met1570Leu/c.4708A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5487,66,5577,"0,0118343195",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,78,Tolerated,"34,39","33,76"
"low bq, low freq, many artifacts, many samples",UPN2_001,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),8292,124,8451,"0,0146728198",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"32,92","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_014,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),14743,222,15074,"0,0147273451",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"31,65","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_015,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),21262,287,21711,"0,0132191055",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"31,58","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_016,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),10674,180,10964,"0,0164173659",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"31,34","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_017,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),8189,110,8370,"0,0131421744",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"31,45","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_018,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),11038,141,11257,"0,0125255397",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"31,57","14,1"
"low bq, low freq, many artifacts, many samples",UPN2_019,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),11872,175,12126,"0,0144317994",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"31,55","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_020,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),9812,153,10034,"0,0152481563",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"31,69","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_021,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),10700,161,10949,"0,0147045392",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"31,32","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_002,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),10551,190,10797,"0,0175974808",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"32,76","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_003,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),1895,30,1936,"0,0154958678",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"32,3","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_022,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),15009,208,15323,"0,0135743653",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"32,02","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_023,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),15649,222,15979,"0,0138932349",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"32,17","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_024,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),7459,133,7646,"0,0173947162",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"31,87","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_025,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),19544,303,20013,"0,0151401589",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"31,5","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_089,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),11633,137,11888,"0,0115242261",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"32,05","14,47"
"low bq, many samples",UPN2_042,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),27002,656,27976,"0,0234486703",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"31,79","14,55"
"low bq, many samples",UPN2_043,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),17421,428,18060,"0,0236987818",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"31,65","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_044,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),5391,104,5551,"0,018735363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"32,42","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_029,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),14379,206,14678,"0,0140346096",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"32,4","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_030,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),16561,230,16921,"0,0135925773",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"31,57","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_031,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),10852,167,11103,"0,0150409799",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"31,79","14,08"
"low bq, low freq, many artifacts, many samples",UPN2_005,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),2903,44,2963,"0,0148498144",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"32,93","14,45"
"low bq, many samples",UPN2_045,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),23272,532,24019,"0,0221491319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"31,76","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_032,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),5086,53,5167,"0,0102574027",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"32,64","14,42"
"low bq, many samples",UPN2_046,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),17977,429,18602,"0,0230620363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"31,82","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_033,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),12654,165,12925,"0,0127659574",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"32,01","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_034,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),4236,53,4310,"0,0122969838",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"32,34","14,64"
"low bq, many samples",UPN2_047,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),30818,709,31846,"0,0222633926",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"31,84","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_048,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),12309,149,12527,"0,0118943083",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"33,26","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_035,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),28144,377,28709,"0,0131317705",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"32,17","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_006,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),11161,207,11435,"0,0181023174",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"32,35","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),12892,257,13274,"0,0193611571",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"32,06","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_050,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),18958,416,19583,"0,0212429148",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"31,92","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_037,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),19943,287,20362,"0,0140948826",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"31,78","14,24"
"low bq, many samples",UPN2_051,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),17113,397,17723,"0,0224002708",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"31,68","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_052,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),15704,350,16219,"0,0215796288",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"32,03","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_038,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),27138,356,27739,"0,0128339161",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"31,8","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_039,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),44777,561,45623,"0,0122964294",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"32,05","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_053,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),22711,464,23411,"0,0198197429",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"31,85","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_054,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),14037,249,14423,"0,0172640921",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"32,27","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_007,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),23505,443,24092,"0,0183878466",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"32,58","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_008,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),34115,690,35048,"0,019687286",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"32,02","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_009,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),27572,540,28276,"0,0190974678",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"32,15","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_010,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),16979,237,17273,"0,013720836",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"33,3","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_011,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),19867,357,20317,"0,0175714919",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"32,77","14,5"
"low bq, many samples",UPN2_055,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),26132,617,27047,"0,0228121418",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"31,49","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_056,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),5808,103,5956,"0,0172934856",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"32,41","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_090,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),9717,118,9957,"0,0118509591",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"31,75","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_057,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),17811,266,18236,"0,0145865321",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"32,79","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_058,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),14890,276,15284,"0,0180581",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"32,51","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_012,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),10542,196,10796,"0,0181548722",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"32,53","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_040,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),43759,651,44732,"0,0145533399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"31,64","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_013,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),6147,102,6278,"0,0162472125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"32,86","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_091,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),10027,126,10277,"0,0122603873",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"31,61","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_096,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),12863,146,13144,"0,0111077298",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"31,89","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_097,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),13635,169,13986,"0,0120835121",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"31,52","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_098,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),11356,116,11588,"0,0100103555",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"32,1","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_099,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),6373,68,6513,"0,0104406571",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"32,21","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_100,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),11105,147,11386,"0,012910592",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"31,85","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_103,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),11651,122,11890,"0,0102607233",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"32,18","14,18"
"low bq, low freq, many artifacts, many samples",UPN2_104,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),14837,163,15157,"0,010754107",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"31,8","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_105,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),11432,117,11674,"0,0100222717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,32,"14,37"
"low bq, low freq, many artifacts, many samples",UPN2_106,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),19963,233,20431,"0,0114042387",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"31,4","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_107,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),22701,233,23166,"0,0100578434",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,32,"14,52"
"low bq, low freq, many artifacts, many samples",UPN2_108,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),18207,221,18626,"0,0118651348",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"31,47","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_110,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),18983,204,19398,"0,0105165481",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"31,98","14,25"
"low bq, low freq, many artifacts",UPN2_111,4,106196377,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met1570Ile/c.4710G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),13980,148,14265,"0,0103750438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,65,Tolerated,"32,19","14,72"
"low freq, many artifacts",UPN2_044,4,106196386,CA,C,frameshift_variant(HIGH||aat/|p.Asn1574fs/c.4721delA|2002|TET2|protein_coding|CODING|ENST00000380013|11|C|INFO_REALIGN_3_PRIME),4376,81,4481,"0,0180763222",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,24",NA
"low freq, many artifacts",UPN2_045,4,106196387,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn1574His/c.4720A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),17893,191,18190,"0,0105002749",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,002",Damaging,"35,2","35,42"
"low freq, many artifacts, many samples",UPN2_092,4,106196387,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn1574His/c.4720A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5110,64,5184,"0,012345679",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,2,Damaging,"35,56","35,88"
"low freq, many artifacts, many samples",UPN2_093,4,106196387,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn1574His/c.4720A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4967,56,5035,"0,011122145",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,2,Damaging,"35,66","35,93"
"low freq, many artifacts, many samples",UPN2_070,4,106196387,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn1574His/c.4720A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),19423,199,19806,"0,0100474604",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,2,Damaging,"35,4","35,38"
"low freq, many artifacts",UPN2_076,4,106196387,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn1574His/c.4720A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),24004,252,24382,"0,0103354934",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,002",Damaging,"35,42","34,94"
"low freq, many artifacts, many samples",UPN2_056,4,106196429,A,T,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile1588Phe/c.4762A>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),4699,56,4776,"0,0117252931",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,18",Neutral,121,Tolerated,"35,49","34,86"
"low freq, many artifacts, many samples",UPN2_090,4,106196451,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met1595Arg/c.4784T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),12476,130,12710,"0,0102281668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,84",Neutral,2,Damaging,"33,37","31,86"
"low bq, low freq, many artifacts, many samples",UPN2_056,4,106196454,A,T,missense_variant(MODERATE|MISSENSE|aAc/aTc|p.Asn1596Ile/c.4787A>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),6826,72,6924,"0,0103986135",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,13",Deleterious,0,Damaging,"32,37","23,93"
"low freq, many artifacts",UPN2_066,4,106196459,T,TAA,frameshift_variant+stop_gained(HIGH||tat/taAAt|p.Tyr1598fs/c.4793_4794insAA|2002|TET2|protein_coding|CODING|ENST00000380013|11|TAA|INFO_REALIGN_3_PRIME),104415,1908,104852,"0,0181970778",0,0,0,1,1,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,51",NA
"low freq, many artifacts",UPN2_056,4,106196463,C,T,missense_variant(MODERATE|MISSENSE|tCc/tTc|p.Ser1599Phe/c.4796C>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),6800,80,6931,"0,011542346",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,22",Neutral,"0,01",Damaging,"32,61","33,39"
"low freq, many artifacts",UPN2_006,4,106196483,G,T,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly1606Cys/c.4816G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),12336,148,12503,"0,0118371591",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,24",Deleterious,"0,006",Damaging,"33,91","30,2"
"low freq, many artifacts",UPN2_056,4,106196487,C,T,missense_variant(MODERATE|MISSENSE|tCa/tTa|p.Ser1607Leu/c.4820C>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),6814,98,6949,"0,0141027486",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,75",Deleterious,"0,062",Tolerated,"33,13","33,87"
"low freq, many artifacts",UPN2_044,4,106196504,A,G,missense_variant(MODERATE|MISSENSE|Aat/Gat|p.Asn1613Asp/c.4837A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),6210,121,6350,"0,0190551181",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,"0,007",Damaging,"34,18","33,32"
"strandbias, many samples, low freq",UPN2_001,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),16659,585,17275,"0,0338639653",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"32,72","31,47"
many samples,UPN2_014,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),22864,687,23600,"0,0291101695",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,2,Damaging,"32,5","31,59"
"strandbias, many samples, low freq",UPN2_015,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),31830,661,32565,"0,0202978658",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"32,58","31,55"
"low freq, many artifacts, many samples",UPN2_016,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),15525,348,15916,"0,0218647901",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,2,Damaging,"32,49","31,29"
"strandbias, many samples, low freq",UPN2_017,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),11501,319,11847,"0,0269266481",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"32,56","31,54"
"low freq, many artifacts, many samples",UPN2_018,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),16193,345,16584,"0,0208031838",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,2,Damaging,"32,57","31,54"
many samples,UPN2_019,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),17863,500,18407,"0,0271635791",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,2,Damaging,"32,56","31,31"
many samples,UPN2_020,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),15800,438,16275,"0,0269124424",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,2,Damaging,"32,5","31,48"
"strandbias, many samples, low freq",UPN2_021,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),16145,493,16676,"0,0295634445",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"32,53","31,55"
"strandbias, many samples, low freq",UPN2_002,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),20801,716,21566,"0,033200408",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"32,73","31,57"
"strandbias, many samples, low freq",UPN2_003,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),3689,108,3803,"0,0283986327",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"32,74","31,91"
"strandbias, many samples, low freq",UPN2_022,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),25423,577,26055,"0,0221454615",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"32,55","31,74"
"strandbias, many samples, low freq",UPN2_023,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),27230,625,27924,"0,0223821802",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"32,49","31,36"
"strandbias, many samples, low freq",UPN2_024,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),12082,226,12347,"0,0183040415",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"32,5","31,25"
"low freq, many artifacts, many samples",UPN2_025,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),28163,603,28836,"0,0209113608",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,2,Damaging,"32,53","31,25"
"inspected, strandbias, many samples, low freq",UPN2_026,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),29816,719,30631,"0,0234729522",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"32,63","31,37"
"low freq, many artifacts, many samples",UPN2_004,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),4135,59,4204,"0,0140342531",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,2,Damaging,"33,05","31,51"
"strandbias, many samples, low freq",UPN2_027,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),31736,859,32679,"0,0262859941",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"32,59","31,51"
"strandbias, many samples, low freq",UPN2_028,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),21686,605,22342,"0,027079044",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"32,6","31,44"
"low freq, many artifacts, many samples",UPN2_043,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),26450,269,26808,"0,0100343181",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,2,Damaging,"31,72","30,61"
"low freq, many artifacts, many samples",UPN2_044,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),9960,149,10143,"0,0146899339",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,2,Damaging,"31,75","30,93"
"strandbias, many samples, low freq",UPN2_029,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),26506,724,27275,"0,0265444546",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"32,58","31,39"
many samples,UPN2_030,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),25073,685,25841,"0,0265082621",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,2,Damaging,"32,56","31,6"
"low freq, many artifacts, many samples",UPN2_031,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),16592,301,16934,"0,0177748908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,2,Damaging,"32,51","31,53"
many samples,UPN2_005,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),5919,227,6171,"0,0367849619",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,2,Damaging,"32,68","31,67"
"strandbias, many samples, low freq",UPN2_032,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),9761,231,10028,"0,0230355006",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"32,44","31,36"
"low freq, many artifacts, many samples",UPN2_046,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),29655,480,30231,"0,0158777414",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,2,Damaging,"31,67","30,9"
"strandbias, many samples, low freq",UPN2_033,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),20764,403,21208,"0,0190022633",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"32,55","31,33"
"low freq, many artifacts, many samples",UPN2_034,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),7629,143,7803,"0,0183262848",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,2,Damaging,"32,59","31,37"
"strandbias, many samples, low freq",UPN2_047,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),46805,501,47501,"0,0105471464",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"31,65","30,79"
"strandbias, many samples, low freq",UPN2_035,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),50008,1310,51439,"0,0254670581",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"32,52","31,44"
"strandbias, many samples, low freq",UPN2_036,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),44711,1384,46210,"0,0299502272",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"32,5","31,51"
"strandbias, many samples, low freq",UPN2_006,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),20558,883,21494,"0,041081232",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"32,68","31,41"
"strandbias, many samples, low freq",UPN2_049,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),21620,242,21934,"0,0110330993",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"31,72","30,36"
"strandbias, many samples, low freq",UPN2_037,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),31392,724,32209,"0,0224781893",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"32,6","31,51"
"strandbias, many samples, low freq",UPN2_038,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),42316,1058,43493,"0,0243257536",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"32,58","31,55"
"strandbias, many samples, low freq",UPN2_039,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),74547,2103,76781,"0,0273895886",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"32,58","31,41"
"strandbias, many samples, low freq",UPN2_053,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),37043,434,37653,"0,011526306",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"31,76","30,31"
"strandbias, many samples, low freq",UPN2_007,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),46310,1469,47943,"0,0306405523",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"32,67","31,38"
"strandbias, many samples, low freq",UPN2_008,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),58198,1678,60025,"0,0279550187",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"32,73","31,43"
"strandbias, many samples, low freq",UPN2_009,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),47470,1194,48839,"0,024447675",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"32,71","31,31"
"strandbias, many samples, low freq",UPN2_010,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),37998,1134,39238,"0,0289005556",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"32,75","31,23"
"strandbias, many samples, low freq",UPN2_011,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),42808,1410,44339,"0,0318004466",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"32,73","31,3"
"strandbias, many samples, low freq",UPN2_057,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),35960,475,36571,"0,0129884335",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"31,66","30,76"
"strandbias, many samples, low freq",UPN2_058,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),31217,692,32036,"0,0216006992",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"31,72","30,94"
"strandbias, many samples, low freq",UPN2_012,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),20691,685,21416,"0,0319854315",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"32,68","31,26"
"strandbias, many samples, low freq",UPN2_060,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),49540,595,50339,"0,0118198613",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"31,46","29,4"
"strandbias, many samples, low freq",UPN2_040,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),68250,1856,70301,"0,0264007624",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"32,52","31,42"
many samples,UPN2_013,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),12927,457,13430,"0,0340282949",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,2,Damaging,"32,63","31,35"
"strandbias, many samples, low freq",UPN2_061,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),48698,595,49475,"0,0120262759",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"31,52","29,82"
"strandbias, many samples, low freq",UPN2_062,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),40291,562,40999,"0,0137076514",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"31,57","30,01"
"strandbias, many samples, low freq",UPN2_063,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),44562,646,45394,"0,0142309556",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"31,47","29,94"
"strandbias, many samples, low freq",UPN2_064,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),51387,591,52106,"0,0113422638",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"31,46","29,43"
"strandbias, many samples, low freq",UPN2_069,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),64153,702,65091,"0,0107849011",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"31,48","29,28"
"strandbias, many samples, low freq",UPN2_070,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),43830,498,44461,"0,0112008277",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"31,53","29,34"
"strandbias, many samples, low freq",UPN2_071,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),26971,423,27483,"0,0153913328",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"31,51","30,24"
"strandbias, many samples, low freq",UPN2_072,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),31598,425,32130,"0,0132275132",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"31,48","30,12"
"strandbias, many samples, low freq",UPN2_075,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),54104,721,55060,"0,0130948057",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"31,39","29,48"
"strandbias, many samples, low freq",UPN2_076,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),53563,610,54319,"0,0112299564",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"31,58","29,56"
"strandbias, many samples, low freq",UPN2_077,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),64364,738,65344,"0,0112940744",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"31,52","29,64"
"strandbias, many samples, low freq",UPN2_078,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),44315,538,44980,"0,0119608715",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"31,55","29,88"
"strandbias, many samples, low freq",UPN2_079,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),30597,395,31092,"0,0127042326",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"31,53","30,44"
"strandbias, many samples, low freq",UPN2_080,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),41722,609,42449,"0,0143466277",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"31,52","30,23"
"low freq, many artifacts, many samples",UPN2_081,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),53781,557,54581,"0,0102050164",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,2,Damaging,"31,37","29,61"
"strandbias, many samples, low freq",UPN2_083,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),64146,797,65190,"0,0122258015",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"31,57","29,59"
"low freq, many artifacts",UPN2_084,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),72567,746,73539,"0,0101442772",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,2,Damaging,"31,52","29,58"
"strandbias, many samples, low freq",UPN2_087,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),87979,944,89240,"0,010578216",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"31,44","29,32"
"strandbias, many samples, low freq",UPN2_088,4,106196515,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn1616Lys/c.4848C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),63205,666,64079,"0,0103934206",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,002",Damaging,"31,37","29,42"
"low bq, low freq, many artifacts",UPN2_041,4,106196519,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1618Asn/c.4852T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9741,100,9880,"0,0101214575",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,69",Deleterious,0,Damaging,"29,35","17,44"
"low freq, many artifacts",UPN2_059,4,106196594,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1643Pro/c.4927T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),16997,198,17273,"0,0114629769",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,09",Neutral,"0,394",Tolerated,"33,01","31,59"
"low freq, many artifacts",UPN2_080,4,106196594,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1643Pro/c.4927T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),13827,144,14027,"0,0102659157",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,09",Neutral,"0,394",Tolerated,"32,89","31,6"
"low freq, many artifacts",UPN2_084,4,106196594,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1643Pro/c.4927T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),20368,265,20739,"0,0127778581",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,09",Neutral,"0,394",Tolerated,"32,87","31,54"
"low freq, many artifacts",UPN2_086,4,106196594,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1643Pro/c.4927T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),17231,253,17566,"0,0144028236",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,09",Neutral,"0,394",Tolerated,"32,98","31,86"
"low freq, many artifacts",UPN2_044,4,106196648,T,C,missense_variant(MODERATE|MISSENSE|Tat/Cat|p.Tyr1661His/c.4981T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),7583,113,7729,"0,0146202614",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,22",Neutral,0,Damaging,"32,9","33,43"
"low freq, many artifacts",UPN2_044,4,106196662,C,A,missense_variant(MODERATE|MISSENSE|gaC/gaA|p.Asp1665Glu/c.4995C>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),10408,126,10559,"0,0119329482",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,84",Neutral,"0,087",Tolerated,"33,55","31,2"
"low bq, low freq, many artifacts",UPN2_041,4,106196743,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys1692Asn/c.5076A>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),27486,297,27931,"0,0106333465",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,1,Damaging,"32,22","24,58"
"low freq, many artifacts",UPN2_044,4,106196751,GT,G,frameshift_variant(HIGH||tat/|p.Tyr1696fs/c.5086delT|2002|TET2|protein_coding|CODING|ENST00000380013|11|G|INFO_REALIGN_3_PRIME),5562,70,5671,"0,012343502",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,17",NA
"low bq, low freq, many artifacts",UPN2_041,4,106196805,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro1713Gln/c.5138C>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),27662,289,28022,"0,0103133252",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,71",Deleterious,1,Damaging,"28,97","18,7"
"low freq, many artifacts, many samples",UPN2_018,4,106196819,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val1718Leu/c.5152G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),14390,154,14580,"0,0105624143",0,0,0,0,1,0,0,0,1,"0,66",NO,COSM41742,haematopoietic_and_lymphoid_tissue,11,NO,rs142312318,NO,"0,002662",NO,NO,"-0,34",Neutral,377,Tolerated,"35,45","35,04"
"low freq, many artifacts",UPN2_004,4,106196819,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val1718Leu/c.5152G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),2937,88,3036,"0,0289855072",0,0,0,0,1,1,0,0,2,"0,66",NO,COSM41742,haematopoietic_and_lymphoid_tissue,11,NO,rs142312318,NO,"0,002662",NO,NO,"-0,34",Neutral,"0,377",Tolerated,"35,26","35,1"
"low freq, many artifacts",UPN2_029,4,106196819,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val1718Leu/c.5152G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),24605,305,24954,"0,0122224894",0,0,0,0,1,1,0,0,2,"0,66",NO,COSM41742,haematopoietic_and_lymphoid_tissue,11,NO,rs142312318,NO,"0,002662",NO,NO,"-0,34",Neutral,"0,377",Tolerated,"35,43","35,27"
"low freq, many artifacts, many samples",UPN2_034,4,106196819,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val1718Leu/c.5152G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),7290,83,7383,"0,0112420425",0,0,0,0,1,0,0,0,1,"0,66",NO,COSM41742,haematopoietic_and_lymphoid_tissue,11,NO,rs142312318,NO,"0,002662",NO,NO,"-0,34",Neutral,377,Tolerated,"35,39","34,6"
"low freq, many artifacts",UPN2_095,4,106196819,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val1718Leu/c.5152G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),19014,212,19253,"0,011011271",0,0,0,0,1,1,0,0,2,"0,66",NO,COSM41742,haematopoietic_and_lymphoid_tissue,11,NO,rs142312318,NO,"0,002662",NO,NO,"-0,34",Neutral,"0,377",Tolerated,"35,29","34,43"
"low freq, many artifacts, many samples",UPN2_111,4,106196819,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val1718Leu/c.5152G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),25186,265,25489,"0,0103966417",0,0,0,0,1,0,0,0,1,"0,66",NO,COSM41742,haematopoietic_and_lymphoid_tissue,11,NO,rs142312318,NO,"0,002662",NO,NO,"-0,34",Neutral,377,Tolerated,"35,27","34,23"
"low freq, many artifacts",UPN2_094,4,106196829,T,G,missense_variant(MODERATE|MISSENSE|tTg/tGg|p.Leu1721Trp/c.5162T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),20752,922,21759,"0,0423732708",0,0,0,1,1,1,0,1,4,"13,4821",NO,COSM5020013,soft_tissue,4,rs34402524,rs34402524,NO,"0,118",NO,YES,"0,03",Neutral,"0,003",Damaging,"35,62","35,23"
"low freq, many artifacts",UPN2_097,4,106196829,T,G,missense_variant(MODERATE|MISSENSE|tTg/tGg|p.Leu1721Trp/c.5162T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),21128,1302,22498,"0,0578718108",0,0,0,1,1,1,0,1,4,"13,4821",NO,COSM5020013,soft_tissue,4,rs34402524,rs34402524,NO,"0,118",NO,YES,"0,03",Neutral,"0,003",Damaging,"35,56","35,28"
"inspected, many artifacts",UPN2_044,4,106196942,C,G,missense_variant(MODERATE|MISSENSE|Cct/Gct|p.Pro1759Ala/c.5275C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),10051,141,10218,"0,0137991779",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,68",Deleterious,"0,21",Tolerated,"32,91","33,04"
"inspected, many artifacts",UPN2_044,4,106196946,C,T,missense_variant(MODERATE|MISSENSE|tCt/tTt|p.Ser1760Phe/c.5279C>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),9990,133,10152,"0,0131008668",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,"0,004",Damaging,"34,17","32,83"
"leakage, freq too low for SNP",UPN2_094,4,106196951,A,G,missense_variant(MODERATE|MISSENSE|Ata/Gta|p.Ile1762Val/c.5284A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),18346,1396,19770,"0,0706120384",0,0,0,0,1,1,0,0,2,"37,335",NO,COSM3760322,"haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1",rs2454206,rs2454206,NO,"0,272",NO,YES,"-0,06",Neutral,"0,047",Damaging,"35,78","35,21"
"low freq, many artifacts",UPN2_105,4,106196951,A,G,missense_variant(MODERATE|MISSENSE|Ata/Gta|p.Ile1762Val/c.5284A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),17824,745,18603,"0,0400473042",0,0,0,0,1,1,0,0,2,"37,335",NO,COSM3760322,"haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1",rs2454206,rs2454206,NO,"0,272",NO,YES,"-0,06",Neutral,"0,047",Damaging,"35,79","35,36"
"low freq, many artifacts",UPN2_044,4,106196957,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His1764Asn/c.5290C>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6285,77,6368,"0,0120917085",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,"0,021",Damaging,"35,27","34,23"
"many samples, low freq, many artifacts",UPN2_001,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),13893,160,14062,"0,0113781823",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,31","35,95"
"many samples, low freq, many artifacts",UPN2_014,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),20298,603,20911,"0,0288364975",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,4","35,79"
"many samples, low freq, many artifacts",UPN2_015,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),29547,1253,30817,"0,0406593763",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,4","35,8"
"many samples, low freq, many artifacts",UPN2_016,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),13895,425,14327,"0,0296642703",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,35","35,87"
"many samples, low freq, many artifacts",UPN2_017,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),10121,385,10509,"0,036635265",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,38","35,79"
"many samples, low freq, many artifacts",UPN2_018,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),13887,509,14405,"0,0353349531",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,42","35,82"
"many samples, low freq, many artifacts",UPN2_019,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),16226,529,16765,"0,0315538324",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,4","35,74"
"many samples, low freq, many artifacts",UPN2_020,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),13439,373,13814,"0,0270015926",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,37","35,81"
"many samples, low freq, many artifacts",UPN2_021,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),15229,559,15795,"0,0353909465",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,4","35,75"
"many samples, low freq, many artifacts",UPN2_002,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),18269,354,18635,"0,0189965119",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,34","35,7"
"many samples, low freq, many artifacts",UPN2_003,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3574,65,3640,"0,0178571429",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,38","35,65"
"many samples, low freq, many artifacts",UPN2_022,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),20048,467,20524,"0,0227538492",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,37","35,75"
"many samples, low freq, many artifacts",UPN2_023,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),22959,691,23663,"0,0292017073",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,36","35,69"
"many samples, low freq, many artifacts",UPN2_024,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),11356,412,11774,"0,034992356",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,36","35,88"
"many samples, low freq, many artifacts",UPN2_025,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),23913,1025,24947,"0,0410871047",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,41","35,76"
"many samples, low freq, many artifacts",UPN2_026,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),26104,881,26999,"0,0326308382",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,38","35,82"
"many samples, low freq, many artifacts",UPN2_004,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2791,73,2864,"0,0254888268",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,43",36
"many samples, low freq, many artifacts",UPN2_027,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),27650,791,28456,"0,0277973011",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,43","35,73"
"many samples, low freq, many artifacts",UPN2_089,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),17905,1223,19141,"0,0638942584",1,0,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,5","35,87"
"many samples, low freq, many artifacts",UPN2_042,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),25540,610,26171,"0,0233082419",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,2","35,7"
"many samples, low freq, many artifacts",UPN2_028,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),19909,387,20306,"0,0190584064",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,45","35,78"
"many samples, low freq, many artifacts",UPN2_043,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),21563,542,22124,"0,0244982824",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,25","35,77"
"many samples, low freq, many artifacts",UPN2_029,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),23447,697,24154,"0,0288565041",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,39","35,66"
"many samples, low freq, many artifacts",UPN2_030,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),22729,722,23465,"0,0307692308",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,39","35,76"
"many samples, low freq, many artifacts",UPN2_031,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),14330,669,15007,"0,0445791964",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,36","35,69"
"many samples, low freq, many artifacts",UPN2_005,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5344,102,5447,"0,0187259042",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,32",36
"many samples, low freq, many artifacts",UPN2_045,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),31688,868,32580,"0,0266421117",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,25","35,78"
"many samples, low freq, many artifacts",UPN2_032,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9125,238,9366,"0,0254110613",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,37","35,61"
"many samples, low freq, many artifacts",UPN2_046,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),25617,428,26061,"0,0164230076",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,29","35,78"
"many samples, low freq, many artifacts",UPN2_033,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),18384,850,19245,"0,0441673162",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,35","35,81"
"many samples, low freq, many artifacts",UPN2_034,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6988,202,7196,"0,0280711506",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,36","35,92"
"many samples, low freq, many artifacts",UPN2_047,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),39041,1103,40171,"0,0274576187",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,2","35,71"
"many samples, low freq, many artifacts",UPN2_048,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6043,81,6130,"0,0132137031",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,03","35,14"
"many samples, low freq, many artifacts",UPN2_035,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),40492,1158,41662,"0,0277951131",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,37","35,85"
"many samples, low freq, many artifacts",UPN2_036,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),43757,1182,44960,"0,0262900356",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,39","35,77"
"many samples, low freq, many artifacts",UPN2_006,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),16447,287,16750,"0,0171343284",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,27","35,68"
"many samples, low freq, many artifacts",UPN2_049,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),18303,377,18694,"0,0201668985",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,24","35,68"
"many samples, low freq, many artifacts",UPN2_037,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),27645,1121,28778,"0,0389533672",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,39","35,81"
"many samples, low freq, many artifacts",UPN2_051,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),24701,1092,25808,"0,0423124613",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,29","35,79"
"many samples, low freq, many artifacts",UPN2_052,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),26692,896,27605,"0,0324578881",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,25","35,68"
"many samples, low freq, many artifacts",UPN2_038,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),38882,1418,40323,"0,0351660343",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,43","35,78"
"many samples, low freq, many artifacts",UPN2_039,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),66967,2327,69335,"0,0335616932",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,39","35,75"
"many samples, low freq, many artifacts",UPN2_053,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),32904,981,33904,"0,028934639",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,27","35,63"
"many samples, low freq, many artifacts",UPN2_054,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),24548,750,25318,"0,029623193",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,23","35,56"
"many samples, low freq, many artifacts",UPN2_007,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),41468,715,42201,"0,0169427265",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,25","35,71"
"many samples, low freq, many artifacts",UPN2_008,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),51733,1005,52768,"0,0190456337",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,23","35,59"
"many samples, low freq, many artifacts",UPN2_009,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),41945,1062,43037,"0,0246764412",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,28","35,75"
"many samples, low freq, many artifacts",UPN2_010,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),31649,632,32309,"0,019561113",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,25","35,57"
"many samples, low freq, many artifacts",UPN2_011,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),37548,781,38352,"0,0203639967",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,24","35,74"
"many samples, low freq, many artifacts",UPN2_055,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),32958,891,33868,"0,0263080194",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,28","35,64"
"many samples, low freq, many artifacts",UPN2_056,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6954,120,7076,"0,0169587337",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,23","35,9"
"many samples, low freq, many artifacts",UPN2_090,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),14765,678,15456,"0,0438664596",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,43","35,74"
"many samples, low freq, many artifacts",UPN2_057,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),33635,719,34380,"0,0209133217",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,22","35,64"
"many samples, low freq, many artifacts",UPN2_058,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),27921,326,28264,"0,011534107",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,2","35,35"
"many samples, low freq, many artifacts",UPN2_059,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),19558,1490,21069,"0,0707200152",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"34,93","35,73"
"many samples, low freq, many artifacts",UPN2_060,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),21005,1008,22042,"0,0457308774",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"34,84","35,74"
"many samples, low freq, many artifacts",UPN2_040,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),59145,1018,60190,"0,0169131085",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,41","35,81"
"many samples, low freq, many artifacts",UPN2_013,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),11018,128,11151,"0,0114787911",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,22","34,95"
"many samples, low freq, many artifacts",UPN2_091,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),11231,237,11472,"0,0206589958",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,39","35,67"
"many samples, low freq, many artifacts",UPN2_092,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9711,304,10018,"0,0303453783",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,43","35,77"
"many samples, low freq, many artifacts",UPN2_093,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),10753,523,11282,"0,0463570289",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,49","35,93"
"many samples, low freq, many artifacts",UPN2_061,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),23714,1166,24902,"0,0468235483",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"34,82","35,63"
"many samples, low freq, many artifacts",UPN2_062,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),19346,735,20099,"0,0365689835",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"34,87","35,56"
"many samples, low freq, many artifacts",UPN2_063,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),20306,905,21232,"0,0426243406",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"34,86","35,65"
"many samples, low freq, many artifacts",UPN2_064,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),12226,367,12609,"0,029106194",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"34,7","35,75"
"many samples, low freq, many artifacts",UPN2_065,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),17399,2021,19439,"0,1039662534",1,1,0,0,1,1,0,0,4,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"34,9","35,65"
"many samples, low freq, many artifacts",UPN2_066,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),30423,5565,36012,"0,1545318227",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"34,89","35,72"
"many samples, low freq, many artifacts",UPN2_067,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),31008,4702,35756,"0,1315024052",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"34,89","35,69"
"many samples, low freq, many artifacts",UPN2_068,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),24347,2180,26542,"0,0821339763",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"34,87","35,56"
"many samples, low freq, many artifacts",UPN2_069,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),27965,1338,29330,"0,0456188203",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"34,82","35,67"
"many samples, low freq, many artifacts",UPN2_070,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),18389,1118,19520,"0,0572745902",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"34,92","35,56"
"many samples, low freq, many artifacts",UPN2_071,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),14944,306,15257,"0,0200563676",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"34,81","35,75"
"many samples, low freq, many artifacts",UPN2_072,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),13973,229,14214,"0,0161108766",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"34,73","35,3"
"many samples, low freq, many artifacts",UPN2_073,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),13562,501,14077,"0,0355899695",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"34,74","35,54"
"many samples, low freq, many artifacts",UPN2_074,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),12956,526,13490,"0,0389918458",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"34,75","35,7"
"many samples, low freq, many artifacts",UPN2_075,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),28224,1557,29806,"0,0522378045",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"34,81","35,71"
"many samples, low freq, many artifacts",UPN2_076,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),25691,1267,26977,"0,0469659339",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"34,89","35,52"
"many samples, low freq, many artifacts",UPN2_077,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),28461,1966,30452,"0,06456062",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"34,84","35,68"
"many samples, low freq, many artifacts",UPN2_078,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),23622,802,24440,"0,0328150573",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"34,84","35,6"
"many samples, low freq, many artifacts",UPN2_079,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),14135,205,14353,"0,0142827283",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"34,82","35,6"
"many samples, low freq, many artifacts",UPN2_080,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),20645,446,21121,"0,0211164244",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"34,75","35,56"
"many samples, low freq, many artifacts",UPN2_081,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),23163,1131,24319,"0,0465068465",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"34,85","35,56"
"many samples, low freq, many artifacts",UPN2_082,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),31225,3701,34964,"0,1058517332",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"34,86","35,66"
"many samples, low freq, many artifacts",UPN2_083,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),28724,2252,31002,"0,0726404748",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"34,94","35,71"
"many samples, low freq, many artifacts",UPN2_084,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),31126,3406,34557,"0,0985617965",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"34,86","35,65"
"many samples, low freq, many artifacts",UPN2_085,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),25397,3726,29153,"0,1278084588",1,1,0,0,1,1,0,0,4,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"34,91","35,66"
"many samples, low freq, many artifacts",UPN2_086,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),18846,2863,21731,"0,1317472735",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"34,95","35,63"
"many samples, low freq, many artifacts",UPN2_087,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),28714,951,29696,"0,0320245151",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"34,82","35,71"
"many samples, low freq, many artifacts",UPN2_088,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),25311,2647,27980,"0,0946032881",1,1,0,0,1,1,0,0,4,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"34,87","35,67"
"many samples, low freq, many artifacts",UPN2_094,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),18230,1537,19772,"0,0777361926",1,0,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,46","35,84"
"many samples, low freq, many artifacts",UPN2_095,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),15903,696,16607,"0,0419100379",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,5","35,85"
"many samples, low freq, many artifacts",UPN2_096,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),18189,1230,19423,"0,0633269835",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,42","35,9"
"many samples, low freq, many artifacts",UPN2_097,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),18763,1115,19886,"0,0560695967",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,45","35,79"
"many samples, low freq, many artifacts",UPN2_098,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),14928,620,15559,"0,0398483193",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,43","35,95"
"many samples, low freq, many artifacts",UPN2_099,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9941,611,10556,"0,0578817734",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,44","35,89"
"many samples, low freq, many artifacts",UPN2_100,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),16160,1451,17617,"0,082363626",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,5","35,91"
"many samples, low freq, many artifacts",UPN2_101,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),15924,1250,17182,"0,0727505529",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,52","35,84"
"many samples, low freq, many artifacts",UPN2_102,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),19024,1283,20314,"0,0631584129",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,46","35,76"
"many samples, low freq, many artifacts",UPN2_103,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),16909,1159,18077,"0,0641146208",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,48","35,83"
"many samples, low freq, many artifacts",UPN2_104,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),20344,1573,21929,"0,0717314971",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,42","35,93"
"many samples, low freq, many artifacts",UPN2_105,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),17140,1451,18606,"0,077985596",1,0,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,45","35,87"
"many samples, low freq, many artifacts",UPN2_106,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),16349,196,16555,"0,0118393235",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,38","35,49"
"many samples, low freq, many artifacts",UPN2_107,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),31923,2429,34369,"0,070674154",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,44","35,85"
"many samples, low freq, many artifacts",UPN2_108,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),25421,1315,26745,"0,0491680688",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,48","35,94"
"many samples, low freq, many artifacts",UPN2_109,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),25659,2228,27897,"0,0798652185",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,47","35,83"
"many samples, low freq, many artifacts",UPN2_110,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),26419,1791,28222,"0,0634611296",1,0,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,47","35,9"
"many samples, low freq, many artifacts",UPN2_111,4,106196967,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser1767Asn/c.5300G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),21904,1630,23543,"0,0692350168",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,rs185223849,NO,"3,93E-005",NO,NO,"-0,57",Neutral,"0,45",Tolerated,"35,46","35,86"
"2nd Illumina, low freq",UPN2_001,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),13523,468,14009,"0,0334070954",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,4","35,72"
low freq,UPN2_014,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),19795,1104,20939,"0,0527245809",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,48","35,78"
low freq,UPN2_015,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),29293,1461,30818,"0,0474073593",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,42","35,76"
low freq,UPN2_016,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),13505,795,14329,"0,0554818899",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,44","35,61"
low freq,UPN2_017,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),9881,603,10500,"0,0574285714",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,52","35,78"
low freq,UPN2_018,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),13673,686,14398,"0,0476455063",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,44","35,65"
low freq,UPN2_019,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),15915,810,16765,"0,0483149418",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,45","35,8"
low freq,UPN2_020,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),13176,614,13813,"0,0444508796",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,49","35,72"
low freq,UPN2_021,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),15017,737,15794,"0,0466632899",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,46","35,67"
low freq,UPN2_002,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),17934,658,18627,"0,0353250658",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,33","35,65"
low freq,UPN2_003,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),3483,155,3639,"0,0425941193",0,0,0,0,1,1,0,1,3,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,31","35,54"
low freq,UPN2_022,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),19566,924,20526,"0,0450160772",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,45","35,73"
low freq,UPN2_023,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),22481,1133,23665,"0,047876611",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,47","35,82"
low freq,UPN2_024,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),11042,705,11774,"0,0598776966",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,45","35,69"
low freq,UPN2_025,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),23584,1296,24944,"0,0519563823",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,47","35,68"
low freq,UPN2_026,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),25498,1439,26998,"0,0533002445",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,45","35,75"
low freq,UPN2_027,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),27080,1320,28457,"0,046385775",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,46","35,71"
low freq,UPN2_089,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),18114,992,19130,"0,051855724",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,38","35,8"
low freq,UPN2_042,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),25615,519,26203,"0,0198068923",0,0,0,0,1,1,0,1,3,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,38","35,47"
low freq,UPN2_028,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),19306,934,20305,"0,0459985225",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,45","35,77"
low freq,UPN2_043,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),21105,928,22114,"0,0419643665",0,0,0,0,1,1,0,1,3,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,37","35,58"
low freq,UPN2_044,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),6170,150,6369,"0,023551578",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,38","35,45"
low freq,UPN2_029,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),23157,959,24154,"0,0397035688",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,46","35,78"
low freq,UPN2_030,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),22298,1116,23465,"0,047560196",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,45","35,76"
low freq,UPN2_031,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),14362,621,15006,"0,0413834466",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,42","35,82"
low freq,UPN2_005,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),5246,186,5444,"0,0341660544",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,38","35,51"
low freq,UPN2_045,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),31006,1502,32583,"0,0460976583",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,31","35,53"
low freq,UPN2_032,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),8891,455,9366,"0,0485799701",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,43","35,86"
low freq,UPN2_033,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),18281,893,19222,"0,0464571845",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,43","35,56"
low freq,UPN2_047,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),39341,701,40170,"0,017450834",0,0,0,0,1,1,0,1,3,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,28","35,45"
low freq,UPN2_035,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),39646,1940,41673,"0,046552924",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,44","35,66"
low freq,UPN2_049,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),18331,311,18693,"0,0166372439",0,0,0,0,1,1,0,1,3,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,33","35,45"
low freq,UPN2_050,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),23355,1537,24984,"0,0615193724",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,41","35,54"
low freq,UPN2_037,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),27253,1465,28778,"0,0509069428",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,4","35,68"
low freq,UPN2_051,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),24632,1105,25801,"0,0428277974",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,33","35,62"
low freq,UPN2_052,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),26303,1206,27606,"0,0436861552",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,3","35,49"
low freq,UPN2_038,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),38261,1944,40320,"0,0482142857",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,46","35,73"
low freq,UPN2_039,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),65757,3426,69337,"0,0494108485",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,45","35,71"
low freq,UPN2_053,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),32444,1385,33903,"0,040851842",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,33","35,5"
low freq,UPN2_054,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),24424,804,25319,"0,0317548086",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,31","35,55"
low freq,UPN2_007,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),40853,1254,42200,"0,0297156398",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,35","35,67"
low freq,UPN2_008,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),50818,1861,52770,"0,0352662498",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,3","35,62"
low freq,UPN2_009,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),41356,1603,43035,"0,037248751",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,33","35,56"
low freq,UPN2_010,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),31236,947,32241,"0,0293725381",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,28","35,72"
low freq,UPN2_011,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),37113,1119,38283,"0,0292296842",0,0,0,0,1,1,0,1,3,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,31","35,65"
low freq,UPN2_055,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),32516,1249,33869,"0,0368773805",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,37","35,52"
low freq,UPN2_056,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),6973,73,7076,"0,010316563",0,0,0,0,1,0,0,1,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,34",36
low freq,UPN2_057,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),32775,1520,34378,"0,0442143231",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,33","35,58"
low freq,UPN2_058,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),27363,832,28268,"0,0294325739",0,0,0,0,1,1,0,1,3,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,33","35,51"
low freq,UPN2_012,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),17084,532,17642,"0,0301553112",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,31","35,54"
low freq,UPN2_060,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),21333,665,22042,"0,0301696761",0,0,0,0,1,1,0,1,3,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,25","35,33"
low freq,UPN2_040,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),56561,3478,60194,"0,0577798452",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,45","35,76"
"leakage, freq too low for SNP",UPN2_013,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),10697,407,11128,"0,0365744069",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,29","35,71"
low freq,UPN2_091,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),10981,482,11473,"0,0420116796",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,41","35,75"
low freq,UPN2_092,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),9573,432,10019,"0,0431180757",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,44","35,58"
low freq,UPN2_093,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),10710,538,11265,"0,0477585442",1,0,0,0,1,1,0,0,3,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,42","35,64"
low freq,UPN2_061,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),23668,1185,24903,"0,0475846284",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,24","35,55"
low freq,UPN2_062,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),19353,711,20096,"0,0353801752",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,17","35,33"
low freq,UPN2_064,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),12374,213,12609,"0,0168926957",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,28","35,5"
low freq,UPN2_066,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),34842,1123,36024,"0,031173662",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,1","35,45"
low freq,UPN2_067,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),34188,1509,35756,"0,0422027072",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,11","35,36"
low freq,UPN2_068,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),25529,962,26542,"0,0362444428",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,13","35,39"
low freq,UPN2_069,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),27993,1282,29333,"0,0437050421",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,18","35,56"
low freq,UPN2_070,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),18717,744,19507,"0,0381401548",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,18","35,49"
low freq,UPN2_071,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),14735,494,15258,"0,0323764583",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,17","35,67"
low freq,UPN2_072,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),13866,325,14212,"0,0228679989",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,31","35,69"
low freq,UPN2_073,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),13652,394,14077,"0,0279889181",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,3","35,34"
low freq,UPN2_074,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),12859,662,13537,"0,0489030066",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,29","35,46"
low freq,UPN2_075,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),28799,928,29806,"0,0311346709",0,0,0,0,1,1,0,1,3,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,2","35,34"
low freq,UPN2_076,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),25826,1103,26975,"0,0408897127",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,13","35,46"
low freq,UPN2_077,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),29067,1322,30451,"0,0434140094",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,21","35,44"
low freq,UPN2_078,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),23627,767,24439,"0,0313842629",0,0,0,0,1,1,0,1,3,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,17","35,4"
low freq,UPN2_079,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),13728,586,14353,"0,0408277015",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,26","35,61"
low freq,UPN2_080,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),20509,574,21123,"0,0271741703",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,23","35,58"
low freq,UPN2_081,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),23881,396,24318,"0,0162842339",0,0,0,0,1,1,0,1,3,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,17","34,94"
low freq,UPN2_082,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),33852,1031,34967,"0,0294849429",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,15","35,47"
"leakage, freq too low for SNP",UPN2_083,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),29816,1142,31007,"0,0368303931",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,14","35,48"
low freq,UPN2_084,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),33486,965,34561,"0,0279216458",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,09","35,54"
low freq,UPN2_085,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),28214,894,29154,"0,0306647458",0,0,0,0,1,1,0,1,3,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,1","35,42"
"leakage, freq too low for SNP",UPN2_086,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),20977,710,21727,"0,0326782345",0,0,0,0,1,1,0,1,3,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,03","35,44"
low freq,UPN2_087,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),28437,1186,29695,"0,0399393837",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,24","35,34"
low freq,UPN2_088,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),27025,919,27980,"0,0328448892",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,18","35,58"
low freq,UPN2_094,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),18714,1035,19771,"0,0523494006",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,39","35,77"
low freq,UPN2_095,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),15644,925,16595,"0,0557396806",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,41","35,76"
low freq,UPN2_096,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),18395,1017,19430,"0,0523417396",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,39","35,6"
low freq,UPN2_097,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),18758,1105,19886,"0,0555667304",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,41","35,65"
low freq,UPN2_098,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),14820,705,15559,"0,0453113953",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,42","35,7"
low freq,UPN2_099,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),9986,561,10557,"0,0531400966",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,42","35,8"
low freq,UPN2_100,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),16552,1041,17619,"0,0590839435",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,4","35,7"
low freq,UPN2_101,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),16344,816,17183,"0,0474887971",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,39","35,81"
low freq,UPN2_102,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),19158,1136,20316,"0,055916519",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,4","35,76"
low freq,UPN2_103,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),17112,952,18078,"0,0526606926",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,39","35,68"
low freq,UPN2_104,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),20673,1230,21934,"0,0560773229",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,4","35,61"
low freq,UPN2_105,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),17549,1036,18609,"0,0556719867",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,42","35,84"
low freq,UPN2_106,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),15742,795,16556,"0,0480188451",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,59","35,73"
low freq,UPN2_107,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),32565,1762,34368,"0,051268622",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,41","35,76"
low freq,UPN2_108,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),25421,1296,26746,"0,0484558439",1,0,0,0,1,1,0,0,3,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,42","35,72"
low freq,UPN2_109,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),26350,1518,27890,"0,0544281104",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,34","35,69"
low freq,UPN2_110,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),26601,1593,28220,"0,0564493267",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,38","35,66"
low freq,UPN2_111,4,106197000,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His1778Arg/c.5333A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),22179,1335,23542,"0,0567071617",0,0,0,0,1,1,0,0,2,"3,017",NO,NO,NO,O,rs62621450,rs62621450,NO,"0,045",NO,YES,"-2,49",Neutral,"0,01",Damaging,"35,35","35,63"
"low freq, many artifacts",UPN2_044,4,106197026,A,G,missense_variant(MODERATE|MISSENSE|Aat/Gat|p.Asn1787Asp/c.5359A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),4747,50,4815,"0,010384216",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,012",Damaging,"33,08","33,98"
"low freq, many artifacts",UPN2_048,4,106197027,A,G,missense_variant(MODERATE|MISSENSE|aAt/aGt|p.Asn1787Ser/c.5360A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),6101,68,6195,"0,010976594",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,"0,232",Tolerated,"33,94","33,51"
"low freq, many artifacts",UPN2_006,4,106197029,G,A,missense_variant(MODERATE|MISSENSE|Gac/Aac|p.Asp1788Asn/c.5362G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9639,102,9833,"0,010373233",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,22",Neutral,"0,011",Damaging,"34,77","34,68"
"low freq, many artifacts",UPN2_044,4,106197031,CA,C,frameshift_variant(HIGH||atg/|p.Met1789fs/c.5365delA|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4642,135,4822,"0,0279966819",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,59",NA
"low freq, many artifacts",UPN2_044,4,106197048,C,T,missense_variant(MODERATE|MISSENSE|gCt/gTt|p.Ala1794Val/c.5381C>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),4735,75,4827,"0,015537601",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,98",Neutral,"0,137",Tolerated,"33,5","34,73"
"low freq, many artifacts",UPN2_064,4,106197071,C,T,missense_variant(MODERATE|MISSENSE|Cca/Tca|p.Pro1802Ser/c.5404C>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),7841,80,7972,"0,0100351229",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,16",Deleterious,"0,087",Tolerated,"32,72","33,75"
"inspected, many artifacts",UPN2_048,4,106197072,C,T,missense_variant(MODERATE|MISSENSE|cCa/cTa|p.Pro1802Leu/c.5405C>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),6075,131,6216,"0,0210746461",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,"0,001",Damaging,"32,03","32,24"
"low bq, low freq, many artifacts",UPN2_044,4,106197092,A,T,missense_variant(MODERATE|MISSENSE|Act/Tct|p.Thr1809Ser/c.5425A>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),2374,30,2410,"0,0124481328",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,"0,079",Tolerated,"34,31","27,37"
"low freq, many artifacts",UPN2_048,4,106197098,T,A,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys1811Ser/c.5431T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3112,33,3158,"0,0104496517",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,4",Neutral,1,Tolerated,"34,72","33,76"
"low freq, many artifacts, many samples",UPN2_048,4,106197107,G,T,stop_gained(HIGH|NONSENSE|Gga/Tga|p.Gly1814*/c.5440G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),3342,54,3399,"0,0158870256",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,66",33
"low freq, many artifacts, many samples",UPN2_006,4,106197116,C,T,missense_variant(MODERATE|MISSENSE|Cac/Tac|p.His1817Tyr/c.5449C>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),7298,83,7400,"0,0112162162",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,534,Tolerated,"35,12","35,07"
"low freq, many artifacts, many samples",UPN2_044,4,106197128,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp1821Tyr/c.5461G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),3061,47,3116,"0,0150834403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,6,Damaging,"35,15","32,64"
"low freq, many artifacts",UPN2_044,4,106197131,G,A,missense_variant(MODERATE|MISSENSE|Gct/Act|p.Ala1822Thr/c.5464G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3078,32,3116,"0,0102695764",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,"0,031",Damaging,"35,06","35,09"
"low freq, many artifacts, many samples",UPN2_044,4,106197141,A,G,missense_variant(MODERATE|MISSENSE|cAg/cGg|p.Gln1825Arg/c.5474A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),3056,51,3115,"0,0163723917",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,45,Damaging,"35,39","35,39"
"many samples, low freq, many artifacts",UPN2_014,4,106197147,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1827Arg/c.5480A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),11359,120,11501,"0,0104338753",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,"0,017",Damaging,"34,95","35,38"
"low freq, many artifacts, many samples",UPN2_022,4,106197147,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1827Arg/c.5480A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),11428,116,11561,"0,0100337341",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,17,Damaging,"34,94","34,98"
"many samples, low freq, many artifacts",UPN2_024,4,106197147,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1827Arg/c.5480A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),6502,76,6592,"0,0115291262",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,"0,017",Damaging,"34,99","35,03"
"many samples, low freq, many artifacts",UPN2_042,4,106197147,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1827Arg/c.5480A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),13116,155,13303,"0,0116515072",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,"0,017",Damaging,"33,76","33,92"
"many samples, low freq, many artifacts",UPN2_045,4,106197147,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1827Arg/c.5480A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),17605,193,17829,"0,0108250603",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,"0,017",Damaging,"34,13","35,03"
"many samples, low freq, many artifacts",UPN2_006,4,106197147,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1827Arg/c.5480A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),7293,94,7400,"0,0127027027",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,"0,017",Damaging,"34,61","35,4"
"many samples, low freq, many artifacts",UPN2_053,4,106197147,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1827Arg/c.5480A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),19186,196,19443,"0,0100807489",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,"0,017",Damaging,"33,97","35,36"
"many samples, low freq, many artifacts",UPN2_054,4,106197147,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1827Arg/c.5480A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),14714,172,14926,"0,011523516",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,"0,017",Damaging,"34,03","35,1"
"low bq, low freq, many artifacts, many samples",UPN2_050,4,106197174,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val1836Glu/c.5507T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3816,40,3879,"0,0103119361",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,23",Neutral,613,Tolerated,"33,72","19,52"
"low bq, low freq, many artifacts",UPN2_055,4,106197174,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val1836Glu/c.5507T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5566,60,5659,"0,01060258",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,23",Neutral,613,Tolerated,"33,42","20,97"
"low bq, low freq, many artifacts, many samples",UPN2_024,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),3148,33,3188,"0,0103513174",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,68","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_025,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),9241,97,9358,"0,0103654627",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,81","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_026,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),7553,84,7649,"0,0109818277",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,83","14,08"
"low bq, low freq, many artifacts, many samples",UPN2_089,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),8114,92,8219,"0,0111935759",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,66","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),10071,117,10237,"0,0114291296",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,18","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),8202,106,8360,"0,0126794258",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,24",14
"low bq, low freq, many artifacts, many samples",UPN2_030,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),6785,77,6901,"0,0111578032",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,75","14,09"
"low bq, low freq, many artifacts, many samples",UPN2_031,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),5355,56,5430,"0,0103130755",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,63","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_045,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),10444,127,10618,"0,0119608212",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,14","14,1"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),9802,122,9958,"0,0122514561",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,14","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_035,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),19201,205,19447,"0,0105414717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,72","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_036,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),17904,185,18146,"0,0101950843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,76","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),4710,58,4797,"0,0120908901",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,03",14
"low bq, low freq, many artifacts, many samples",UPN2_050,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),7604,92,7746,"0,0118770979",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,12","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),9244,96,9393,"0,0102203769",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,36","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_052,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),7587,109,7727,"0,0141063802",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,03","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_053,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),11165,154,11370,"0,0135444151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"29,97","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_054,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),7736,110,7883,"0,0139540784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,02","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_055,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),11168,130,11356,"0,0114476928",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,16","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_090,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),5172,61,5245,"0,0116301239",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,71",14
"low bq, low freq, many artifacts, many samples",UPN2_057,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),8702,126,8879,"0,0141907873",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,02","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_058,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),9948,117,10098,"0,0115864528",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,19",14
"low bq, low freq, many artifacts, many samples",UPN2_059,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),13998,256,14300,"0,0179020979",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"29,48","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_060,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),14341,262,14640,"0,0178961749",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"29,4","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_091,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),3355,39,3401,"0,0114672155",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,8","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_092,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),2917,30,2952,"0,0101626016",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,8","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_093,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),3022,35,3060,"0,0114379085",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,89",14
"low bq, low freq, many artifacts, many samples",UPN2_061,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),14647,222,14940,"0,0148594378",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"29,53","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_062,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),12401,211,12635,"0,0166996438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"29,42","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_063,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),13073,207,13312,"0,0155498798",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"29,51","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_064,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),9253,151,9433,"0,0160076328",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"29,51","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_065,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),15994,270,16294,"0,0165705168",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"29,45","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_066,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),34388,624,35115,"0,0177701837",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"29,41","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_067,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),38950,705,39746,"0,017737634",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"29,54","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_068,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),21329,386,21759,"0,0177397858",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"29,32","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_069,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),20975,349,21383,"0,0163213768",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"29,38","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_070,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),13024,236,13280,"0,0177710843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"29,39","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_071,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),9042,157,9217,"0,017033742",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"29,31","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),9450,173,9641,"0,0179441967",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"29,46","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),10546,168,10726,"0,0156628753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"29,43","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_074,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),16094,290,16426,"0,0176549373",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"29,5","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_075,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),18807,328,19189,"0,0170931263",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"29,55","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_076,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),17415,311,17765,"0,0175063327",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"29,49","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_077,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),22063,392,22511,"0,0174137089",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"29,5","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_078,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),13646,253,13929,"0,0181635437",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"29,4","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_079,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),10082,167,10280,"0,0162451362",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"29,32","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_080,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),13096,257,13394,"0,019187696",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"29,39","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),12594,238,12863,"0,0185026821",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"29,6","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_082,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),31020,543,31633,"0,0171656182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"29,51","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_083,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),21299,376,21732,"0,0173016749",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"29,43","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_084,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),24023,432,24528,"0,0176125245",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"29,34","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_085,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),32987,583,33687,"0,0173063793",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"29,45","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_086,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),29873,533,30482,"0,0174857293",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"29,43","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_087,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),29562,502,30147,"0,0166517398",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"29,4","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_088,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),20329,369,20753,"0,0177805618",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"29,45","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_094,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),9245,124,9392,"0,0132027257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,71","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_095,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),7433,90,7540,"0,0119363395",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,69","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_096,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),8532,128,8678,"0,0147499424",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,78","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_097,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),9239,124,9392,"0,0132027257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,88","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_098,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),6262,86,6355,"0,0135326515",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,81","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_099,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),4477,64,4550,"0,0140659341",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,83","14,2"
"low bq, low freq, many artifacts, many samples",UPN2_100,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),8098,93,8209,"0,0113290291",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,94","14,08"
"low bq, low freq, many artifacts, many samples",UPN2_101,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),6859,88,6970,"0,012625538",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,55","14,15"
"low bq, low freq, many artifacts, many samples",UPN2_102,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),7817,108,7953,"0,0135797812",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,79","14,06"
"low bq, low freq, many artifacts, many samples",UPN2_103,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),8313,122,8444,"0,0144481288",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,69","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_104,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),10231,127,10373,"0,012243324",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,77","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_105,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),8195,92,8312,"0,0110683349",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,77",14
"low bq, low freq, many artifacts, many samples",UPN2_106,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),10689,156,10873,"0,0143474662",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,73","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_107,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),13884,162,14076,"0,0115089514",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,74","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_108,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),11191,127,11343,"0,0111963325",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,88","14,06"
"low bq, low freq, many artifacts, many samples",UPN2_109,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),11712,149,11889,"0,0125325932",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,83","14,12"
"low bq, low freq, many artifacts, many samples",UPN2_110,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),13180,160,13376,"0,0119617225",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,74","14,13"
"low bq, low freq, many artifacts",UPN2_111,4,106197177,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1837Gly/c.5510C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),9224,96,9339,"0,0102794732",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,344,Tolerated,"30,65","14,21"
"low freq, many artifacts",UPN2_006,4,106197195,AC,A,frameshift_variant(HIGH||aac/|p.Asn1843fs/c.5529delC|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4925,60,5010,"0,0119760479",0,0,0,1,1,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,39",NA
"low bq, low freq, many artifacts, many samples",UPN2_062,4,106197199,T,G,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp1844Glu/c.5532T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),12559,132,12769,"0,0103375362",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,282,Tolerated,"29,44","15,51"
"low bq, low freq, many artifacts, many samples",UPN2_071,4,106197199,T,G,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp1844Glu/c.5532T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),9110,95,9247,"0,0102736022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,282,Tolerated,"29,49",14
"low bq, low freq, many artifacts, many samples",UPN2_076,4,106197199,T,G,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp1844Glu/c.5532T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),17574,182,17865,"0,0101875175",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,282,Tolerated,"29,45","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_077,4,106197199,T,G,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp1844Glu/c.5532T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),22308,238,22684,"0,0104919767",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,282,Tolerated,"29,47","15,58"
"low bq, low freq, many artifacts",UPN2_086,4,106197199,T,G,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp1844Glu/c.5532T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),30192,307,30666,"0,0100110872",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,282,Tolerated,"29,48","15,69"
"low bq, many samples",UPN2_059,4,106197204,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1846Gly/c.5537T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),13795,496,14362,"0,03453558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,1,Damaging,"28,23","14,64"
"low bq, many samples",UPN2_060,4,106197204,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1846Gly/c.5537T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),14133,518,14727,"0,0351734909",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,1,Damaging,"28,05","15,01"
"low bq, many samples",UPN2_061,4,106197204,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1846Gly/c.5537T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),14519,491,15073,"0,0325748026",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,1,Damaging,"28,15","14,87"
"low bq, many samples",UPN2_062,4,106197204,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1846Gly/c.5537T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),12226,477,12766,"0,0373648755",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,1,Damaging,"28,03","15,04"
"low bq, many samples",UPN2_063,4,106197204,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1846Gly/c.5537T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),12918,436,13407,"0,0325203252",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,1,Damaging,"28,24","14,77"
"low bq, many samples",UPN2_064,4,106197204,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1846Gly/c.5537T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),9133,331,9508,"0,0348127892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,1,Damaging,"28,14","15,02"
"low bq, many samples",UPN2_065,4,106197204,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1846Gly/c.5537T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),15735,558,16396,"0,0340326909",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,1,Damaging,"28,17","14,91"
"low bq, many samples",UPN2_066,4,106197204,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1846Gly/c.5537T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),33980,1189,35368,"0,0336179597",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,1,Damaging,"28,06",15
"low bq, many samples",UPN2_067,4,106197204,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1846Gly/c.5537T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),38441,1282,39967,"0,0320764631",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,1,Damaging,"28,23","14,97"
"low bq, many samples",UPN2_068,4,106197204,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1846Gly/c.5537T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),20963,795,21869,"0,0363528282",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,1,Damaging,"28,07","15,16"
"low bq, many samples",UPN2_069,4,106197204,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1846Gly/c.5537T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),20678,752,21540,"0,034911792",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,1,Damaging,"28,07","15,09"
"low bq, many samples",UPN2_070,4,106197204,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1846Gly/c.5537T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),12822,447,13345,"0,0334956913",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,1,Damaging,"28,02","14,96"
"low bq, many samples",UPN2_071,4,106197204,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1846Gly/c.5537T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),8858,335,9242,"0,0362475655",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,1,Damaging,"28,08","15,21"
"low bq, many samples",UPN2_072,4,106197204,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1846Gly/c.5537T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),9305,355,9712,"0,0365527183",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,1,Damaging,"28,26","14,9"
"low bq, many samples",UPN2_073,4,106197204,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1846Gly/c.5537T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),10411,329,10785,"0,0305053315",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,1,Damaging,"28,13","14,71"
"low bq, many samples",UPN2_074,4,106197204,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1846Gly/c.5537T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),15889,551,16533,"0,0333272848",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,1,Damaging,"28,14","14,91"
"low bq, many samples",UPN2_075,4,106197204,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1846Gly/c.5537T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),18554,653,19293,"0,0338464728",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,1,Damaging,"28,25","14,98"
"low bq, many samples",UPN2_076,4,106197204,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1846Gly/c.5537T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),17146,640,17861,"0,0358322602",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,1,Damaging,"28,1","14,77"
"low bq, many samples",UPN2_077,4,106197204,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1846Gly/c.5537T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),21780,803,22678,"0,0354087662",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,1,Damaging,"28,16","15,23"
"low bq, many samples",UPN2_078,4,106197204,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1846Gly/c.5537T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),13438,499,14013,"0,0356097909",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,1,Damaging,"28,11","14,89"
"low bq, many samples",UPN2_079,4,106197204,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1846Gly/c.5537T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),9926,340,10343,"0,0328724741",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,1,Damaging,"28,19","14,95"
"low bq, many samples",UPN2_080,4,106197204,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1846Gly/c.5537T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),12912,475,13449,"0,035318611",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,1,Damaging,"28,27","14,91"
"low bq, many samples",UPN2_081,4,106197204,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1846Gly/c.5537T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),12388,480,12931,"0,037120099",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,1,Damaging,"28,23","15,25"
"low bq, many samples",UPN2_082,4,106197204,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1846Gly/c.5537T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),30592,1040,31826,"0,0326776849",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,1,Damaging,"28,11","15,05"
"low bq, many samples",UPN2_083,4,106197204,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1846Gly/c.5537T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),21034,760,21894,"0,0347127067",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,1,Damaging,"28,06","15,11"
"low bq, many samples",UPN2_084,4,106197204,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1846Gly/c.5537T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),23690,891,24699,"0,036074335",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,1,Damaging,"28,15","15,08"
"low bq, many samples",UPN2_085,4,106197204,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1846Gly/c.5537T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),32599,1163,33902,"0,0343047608",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,1,Damaging,"28,18","14,95"
"low bq, many samples",UPN2_086,4,106197204,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1846Gly/c.5537T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),29461,1052,30660,"0,0343118069",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,1,Damaging,"28,08","14,9"
"low bq, many samples",UPN2_087,4,106197204,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1846Gly/c.5537T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),29121,1023,30313,"0,0337478969",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,1,Damaging,"28,13",15
"low bq, many samples",UPN2_088,4,106197204,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1846Gly/c.5537T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),20092,673,20869,"0,0322487901",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,1,Damaging,"28,21","14,87"
"low bq, low freq, many artifacts",UPN2_095,4,106197204,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1846Gly/c.5537T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),7482,80,7586,"0,0105457422",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,1,Damaging,"29,89","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106197209,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser1848Ala/c.5542T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),9797,101,9977,"0,0101232836",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,72",Deleterious,3,Damaging,"28,7","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106197209,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser1848Ala/c.5542T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),4709,49,4803,"0,0102019571",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,72",Deleterious,3,Damaging,"28,68","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_054,4,106197209,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser1848Ala/c.5542T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),7790,82,7927,"0,0103443926",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,72",Deleterious,3,Damaging,"28,67","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_056,4,106197209,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser1848Ala/c.5542T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),1636,25,1673,"0,0149432158",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,72",Deleterious,3,Damaging,"28,39","14,28"
"low bq, many samples",UPN2_059,4,106197209,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser1848Ala/c.5542T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),13871,437,14362,"0,0304275171",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,72",Deleterious,3,Damaging,28,"14,49"
"low bq, many samples",UPN2_060,4,106197209,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser1848Ala/c.5542T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),14147,506,14728,"0,0343563281",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,72",Deleterious,3,Damaging,"27,97","14,59"
"low bq, many samples",UPN2_061,4,106197209,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser1848Ala/c.5542T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),14494,491,15072,"0,0325769639",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,72",Deleterious,3,Damaging,"28,06","14,82"
"low bq, many samples",UPN2_062,4,106197209,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser1848Ala/c.5542T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),12293,426,12764,"0,0333751175",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,72",Deleterious,3,Damaging,"27,85","14,67"
"low bq, many samples",UPN2_063,4,106197209,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser1848Ala/c.5542T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),12944,396,13404,"0,0295434199",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,72",Deleterious,3,Damaging,"28,06","15,05"
"low bq, many samples",UPN2_064,4,106197209,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser1848Ala/c.5542T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),9134,328,9503,"0,0345154162",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,72",Deleterious,3,Damaging,"28,13","15,42"
"low bq, many samples",UPN2_065,4,106197209,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser1848Ala/c.5542T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),15781,514,16396,"0,0313491095",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,72",Deleterious,3,Damaging,"28,07","15,02"
"low bq, many samples",UPN2_066,4,106197209,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser1848Ala/c.5542T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),34122,1025,35368,"0,0289809998",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,72",Deleterious,3,Damaging,"27,9","14,77"
"low bq, many samples",UPN2_067,4,106197209,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser1848Ala/c.5542T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),38543,1197,39954,"0,0299594534",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,72",Deleterious,3,Damaging,"28,15","14,88"
"low bq, many samples",UPN2_068,4,106197209,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser1848Ala/c.5542T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),21027,737,21867,"0,0337037545",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,72",Deleterious,3,Damaging,"27,96","14,62"
"low bq, many samples",UPN2_069,4,106197209,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser1848Ala/c.5542T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),20748,703,21541,"0,0326354394",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,72",Deleterious,3,Damaging,"27,93","14,73"
"low bq, many samples",UPN2_070,4,106197209,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser1848Ala/c.5542T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),12797,488,13344,"0,0365707434",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,72",Deleterious,3,Damaging,"27,85","14,93"
"low bq, many samples",UPN2_071,4,106197209,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser1848Ala/c.5542T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),8895,302,9241,"0,0326804458",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,72",Deleterious,3,Damaging,"28,01","14,59"
"low bq, many samples",UPN2_072,4,106197209,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser1848Ala/c.5542T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),9357,312,9710,"0,0321318229",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,72",Deleterious,3,Damaging,"28,11","14,44"
"low bq, many samples",UPN2_073,4,106197209,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser1848Ala/c.5542T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),10388,319,10783,"0,0295836038",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,72",Deleterious,3,Damaging,"28,22","14,95"
"low bq, many samples",UPN2_074,4,106197209,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser1848Ala/c.5542T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),15942,512,16534,"0,0309664933",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,72",Deleterious,3,Damaging,"28,03","14,81"
"low bq, many samples",UPN2_075,4,106197209,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser1848Ala/c.5542T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),18639,546,19291,"0,0283033539",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,72",Deleterious,3,Damaging,"28,07","14,77"
"low bq, many samples",UPN2_076,4,106197209,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser1848Ala/c.5542T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),17174,588,17863,"0,0329172032",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,72",Deleterious,3,Damaging,"27,94","14,75"
"low bq, many samples",UPN2_077,4,106197209,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser1848Ala/c.5542T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),21831,731,22675,"0,0322381477",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,72",Deleterious,3,Damaging,"27,95","14,7"
"low bq, many samples",UPN2_078,4,106197209,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser1848Ala/c.5542T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),13501,451,14012,"0,0321866971",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,72",Deleterious,3,Damaging,"27,92","15,02"
"low bq, many samples",UPN2_079,4,106197209,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser1848Ala/c.5542T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),9955,330,10340,"0,0319148936",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,72",Deleterious,3,Damaging,"27,98","14,9"
"low bq, many samples",UPN2_080,4,106197209,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser1848Ala/c.5542T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),12957,438,13444,"0,0325795894",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,72",Deleterious,3,Damaging,"28,01","14,53"
"low bq, many samples",UPN2_081,4,106197209,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser1848Ala/c.5542T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),12479,390,12930,"0,030162413",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,72",Deleterious,3,Damaging,"28,09","14,71"
"low bq, many samples",UPN2_082,4,106197209,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser1848Ala/c.5542T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),30584,1084,31825,"0,0340612726",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,72",Deleterious,3,Damaging,"28,08","14,59"
"low bq, many samples",UPN2_083,4,106197209,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser1848Ala/c.5542T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),21057,713,21893,"0,0325674873",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,72",Deleterious,3,Damaging,28,"14,75"
"low bq, many samples",UPN2_084,4,106197209,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser1848Ala/c.5542T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),23789,798,24698,"0,0323103085",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,72",Deleterious,3,Damaging,"28,03","14,86"
"low bq, many samples",UPN2_085,4,106197209,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser1848Ala/c.5542T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),32632,1118,33896,"0,0329832429",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,72",Deleterious,3,Damaging,"28,05","14,91"
"low bq, many samples",UPN2_086,4,106197209,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser1848Ala/c.5542T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),29473,1042,30657,"0,0339889748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,72",Deleterious,3,Damaging,28,"14,72"
"low bq, many samples",UPN2_087,4,106197209,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser1848Ala/c.5542T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),29174,999,30308,"0,0329615943",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,72",Deleterious,3,Damaging,"28,05","14,79"
low bq,UPN2_088,4,106197209,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser1848Ala/c.5542T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),20040,690,20861,"0,033076075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,72",Deleterious,3,Damaging,"28,13","14,66"
"low freq, many artifacts",UPN2_056,4,106197215,A,G,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser1850Gly/c.5548A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),1648,20,1673,"0,0119545726",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,42",Deleterious,"0,003",Damaging,"32,75","32,15"
"low bq, low freq, many artifacts, many samples",UPN2_064,4,106197227,T,G,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe1854Val/c.5560T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),9349,97,9496,"0,0102148273",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,34",Deleterious,"0,01",Damaging,"28,68","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_068,4,106197227,T,G,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe1854Val/c.5560T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),21472,225,21853,"0,0102960692",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,34",Deleterious,"0,01",Damaging,"28,47","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_076,4,106197227,T,G,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe1854Val/c.5560T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),17543,183,17853,"0,0102503781",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,34",Deleterious,"0,01",Damaging,"28,45","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_059,4,106197240,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1858Ala/c.5573A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),14120,160,14335,"0,0111614928",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,32,Damaging,"29,91","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_060,4,106197240,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1858Ala/c.5573A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),14473,159,14702,"0,0108148551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,32,Damaging,"29,76","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_061,4,106197240,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1858Ala/c.5573A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),14830,162,15053,"0,0107619744",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,32,Damaging,"29,77","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_062,4,106197240,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1858Ala/c.5573A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),12536,137,12747,"0,0107476269",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,32,Damaging,"29,72","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_063,4,106197240,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1858Ala/c.5573A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),13191,137,13393,"0,0102292242",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,32,Damaging,"29,87","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_064,4,106197240,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1858Ala/c.5573A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),9345,96,9489,"0,0101169776",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,32,Damaging,"30,01","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_065,4,106197240,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1858Ala/c.5573A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),16092,197,16365,"0,0120378857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,32,Damaging,"30,05","16,4"
"low bq, low freq, many artifacts, many samples",UPN2_066,4,106197240,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1858Ala/c.5573A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),34715,384,35298,"0,0108788033",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,32,Damaging,"29,93","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_067,4,106197240,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1858Ala/c.5573A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),39284,406,39846,"0,0101892285",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,32,Damaging,"30,07","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_068,4,106197240,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1858Ala/c.5573A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),21493,223,21837,"0,0102120255",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,32,Damaging,"29,96","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_069,4,106197240,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1858Ala/c.5573A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),21117,259,21494,"0,0120498744",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,32,Damaging,"29,93","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_070,4,106197240,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1858Ala/c.5573A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),13089,154,13322,"0,0115598259",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,32,Damaging,"29,87","15,66"
"low bq, low freq, many artifacts, many samples",UPN2_071,4,106197240,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1858Ala/c.5573A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),9068,108,9225,"0,0117073171",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,32,Damaging,"30,02","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_074,4,106197240,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1858Ala/c.5573A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),16248,187,16505,"0,0113299",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,32,Damaging,"29,86","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_076,4,106197240,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1858Ala/c.5573A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),17567,203,17837,"0,0113808376",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,32,Damaging,"29,81","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_077,4,106197240,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1858Ala/c.5573A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),22239,266,22637,"0,0117506737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,32,Damaging,"29,86","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_078,4,106197240,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1858Ala/c.5573A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),13739,165,13994,"0,0117907675",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,32,Damaging,"29,8","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_083,4,106197240,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1858Ala/c.5573A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),21491,240,21854,"0,0109819713",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,32,Damaging,"29,9","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_084,4,106197240,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1858Ala/c.5573A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),24218,294,24653,"0,0119255263",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,32,Damaging,"29,95","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_085,4,106197240,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1858Ala/c.5573A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),33268,351,33842,"0,0103717274",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,32,Damaging,"29,97","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_086,4,106197240,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1858Ala/c.5573A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),30150,312,30618,"0,0101900843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,32,Damaging,"29,86","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_087,4,106197240,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1858Ala/c.5573A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),29764,315,30236,"0,0104180447",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,32,Damaging,"30,09","14,7"
"low bq, low freq, many artifacts",UPN2_088,4,106197240,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1858Ala/c.5573A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),20494,213,20798,"0,0102413694",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,32,Damaging,"29,86","14,49"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_059,4,106197258,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1864Gly/c.5591T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),7119,98,7252,"0,0135135135",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,34",Deleterious,0,Damaging,"23,15","14,21"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_060,4,106197258,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1864Gly/c.5591T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),7301,101,7438,"0,0135789191",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,34",Deleterious,0,Damaging,"23,12","15,24"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,4,106197258,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1864Gly/c.5591T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),7439,108,7593,"0,014223627",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,34",Deleterious,0,Damaging,"22,99","15,1"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,4,106197258,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1864Gly/c.5591T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),6306,110,6465,"0,0170146945",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,34",Deleterious,0,Damaging,"23,01","14,59"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,4,106197258,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1864Gly/c.5591T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),6651,83,6761,"0,0122762905",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,34",Deleterious,0,Damaging,"22,96","14,24"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,4,106197258,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1864Gly/c.5591T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),4716,54,4795,"0,011261731",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,34",Deleterious,0,Damaging,"23,17","14,8"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_065,4,106197258,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1864Gly/c.5591T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),8098,114,8278,"0,0137714424",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,34",Deleterious,0,Damaging,"22,93","14,78"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_066,4,106197258,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1864Gly/c.5591T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),17537,237,17853,"0,0132750798",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,34",Deleterious,0,Damaging,"22,96","14,59"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_068,4,106197258,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1864Gly/c.5591T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),10818,172,11050,"0,0155656109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,34",Deleterious,0,Damaging,"22,95","14,55"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_069,4,106197258,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1864Gly/c.5591T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),10664,149,10871,"0,0137061908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,34",Deleterious,0,Damaging,"22,95","14,48"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_070,4,106197258,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1864Gly/c.5591T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),6613,92,6743,"0,0136437787",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,34",Deleterious,0,Damaging,"22,97","14,7"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,4,106197258,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1864Gly/c.5591T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),4603,50,4671,"0,010704346",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,34",Deleterious,0,Damaging,"22,8","14,58"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,4,106197258,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1864Gly/c.5591T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),4818,67,4903,"0,013665103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,34",Deleterious,0,Damaging,"22,91","15,18"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,4,106197258,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1864Gly/c.5591T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),5344,62,5437,"0,0114033474",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,34",Deleterious,0,Damaging,"23,27","14,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,4,106197258,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1864Gly/c.5591T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),8200,110,8342,"0,0131862863",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,34",Deleterious,0,Damaging,"23,09","14,53"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_075,4,106197258,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1864Gly/c.5591T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),9536,121,9722,"0,0124459988",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,34",Deleterious,0,Damaging,"23,38","14,46"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,4,106197258,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1864Gly/c.5591T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),8832,119,9002,"0,0132192846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,34",Deleterious,0,Damaging,"22,83","14,23"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,4,106197258,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1864Gly/c.5591T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),11209,154,11434,"0,0134686024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,34",Deleterious,0,Damaging,"22,99","14,8"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,4,106197258,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1864Gly/c.5591T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),6921,99,7053,"0,0140365802",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,34",Deleterious,0,Damaging,"23,38","14,42"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_079,4,106197258,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1864Gly/c.5591T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),5141,66,5222,"0,0126388357",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,34",Deleterious,0,Damaging,"23,1",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,4,106197258,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1864Gly/c.5591T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),6655,96,6778,"0,0141634701",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,34",Deleterious,0,Damaging,"23,26","15,07"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_081,4,106197258,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1864Gly/c.5591T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),6426,96,6548,"0,0146609652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,34",Deleterious,0,Damaging,"23,06","14,22"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_082,4,106197258,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1864Gly/c.5591T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),15779,206,16078,"0,0128125389",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,34",Deleterious,0,Damaging,"23,03","14,67"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,4,106197258,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1864Gly/c.5591T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),10847,144,11039,"0,0130446598",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,34",Deleterious,0,Damaging,"22,94","14,98"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,4,106197258,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1864Gly/c.5591T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),12229,192,12482,"0,0153821503",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,34",Deleterious,0,Damaging,"23,03","14,78"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_085,4,106197258,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1864Gly/c.5591T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),16825,240,17134,"0,0140072371",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,34",Deleterious,0,Damaging,"23,02","14,49"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,4,106197258,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1864Gly/c.5591T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),15188,223,15487,"0,0143991735",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,34",Deleterious,0,Damaging,"22,92","14,63"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_087,4,106197258,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1864Gly/c.5591T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),15007,194,15290,"0,0126880314",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,34",Deleterious,0,Damaging,"22,9","14,21"
"low bq, bad alignment, low freq, many artifacts",UPN2_088,4,106197258,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1864Gly/c.5591T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),10348,116,10521,"0,0110255679",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,34",Deleterious,0,Damaging,"23,01","14,69"
"low freq, many artifacts",UPN2_006,4,106197272,G,T,missense_variant(MODERATE|MISSENSE|Ggg/Tgg|p.Gly1869Trp/c.5605G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),2516,49,2574,"0,019036519",0,0,0,0,1,0,0,0,1,NO,NO,COSM43523,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-7,2",Deleterious,0,Damaging,"34,37","30,9"
"low freq, many artifacts",UPN2_049,4,106197272,G,T,missense_variant(MODERATE|MISSENSE|Ggg/Tgg|p.Gly1869Trp/c.5605G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),2433,27,2477,"0,0109002826",0,0,0,0,1,0,0,1,2,NO,NO,COSM43523,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-7,2",Deleterious,0,Damaging,"34,29","30,81"
"low freq, many artifacts",UPN2_044,4,106197372,AC,A,frameshift_variant(HIGH||cag/|p.Gln1903fs/c.5707delC|2002|TET2|protein_coding|CODING|ENST00000380013|11|A|INFO_REALIGN_3_PRIME),9977,122,10216,"0,0119420517",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,31",NA
"low freq, many artifacts",UPN2_004,4,106197386,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met1907Leu/c.5719A>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),2718,29,2751,"0,0105416212",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"7,94E-005",NO,NO,"0,17",Neutral,669,Tolerated,"34,86","31,14"
"low freq, many artifacts",UPN2_041,4,106197402,A,T,missense_variant(MODERATE|MISSENSE|cAt/cTt|p.His1912Leu/c.5735A>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),7682,150,7876,"0,0190452006",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,95",Deleterious,0,Damaging,"33,88","30,55"
"low freq, many artifacts",UPN2_044,4,106197414,T,A,missense_variant(MODERATE|MISSENSE|cTt/cAt|p.Leu1916His/c.5747T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),10047,120,10222,"0,0117393856",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,87",Deleterious,"0,001",Damaging,"32,59","30,58"
"low freq, many artifacts",UPN2_044,4,106197417,G,T,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp1917Leu/c.5750G>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),10059,124,10220,"0,0121330724",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-10,02",Deleterious,3,Damaging,"32,96","30,25"
many samples,UPN2_001,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),14532,370,14970,"0,0247160989",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"34,19","31,35"
"many samples, low freq, many artifacts",UPN2_014,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),18419,370,18842,"0,0196369812",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,"0,001",Damaging,"34,07","31,41"
"many samples, low freq, many artifacts",UPN2_015,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),27722,471,28286,"0,016651347",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,"0,001",Damaging,"33,95","31,48"
many samples,UPN2_016,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),12906,314,13262,"0,0236766702",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"33,9","31,63"
"low freq, many artifacts, many samples",UPN2_017,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),8439,182,8656,"0,021025878",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"34,16","31,07"
"low freq, many artifacts, many samples",UPN2_018,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),12949,239,13229,"0,0180663693",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"33,95","31,44"
"many samples, low freq, many artifacts",UPN2_019,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),15591,364,16000,"0,02275",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,"0,001",Damaging,"34,06","31,21"
"low freq, many artifacts, many samples",UPN2_020,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),11403,208,11646,"0,0178602095",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"34,22","31,27"
"many samples, low freq, many artifacts",UPN2_021,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),14276,358,14686,"0,0243769576",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,"0,001",Damaging,"33,98","31,49"
many samples,UPN2_002,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),17625,425,18102,"0,0234780687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"34,21","31,13"
"low freq, many artifacts, many samples",UPN2_003,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),3477,65,3556,"0,0182789651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"34,13","31,83"
"low freq, many artifacts, many samples",UPN2_022,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),20907,440,21406,"0,0205549846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"34,02","31,44"
"many samples, low freq, many artifacts",UPN2_023,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),21319,385,21786,"0,0176718994",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,"0,001",Damaging,"34,05","31,56"
"low freq, many artifacts, many samples",UPN2_024,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),9870,170,10067,"0,0168868581",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"34,15","31,48"
"low freq, many artifacts, many samples",UPN2_025,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),23246,446,23775,"0,0187592008",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"34,05","31,4"
"many samples, low freq, many artifacts",UPN2_026,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),23711,529,24305,"0,0217650689",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,"0,001",Damaging,"34,05","31,34"
many samples,UPN2_004,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),2281,129,2413,"0,0534604227",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"33,6","31,33"
"many samples, low freq, many artifacts",UPN2_027,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),26448,600,27138,"0,0221092195",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,"0,001",Damaging,"34,03","31,43"
many samples,UPN2_028,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),18794,497,19341,"0,0256967065",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"34,02","31,03"
"low freq, many artifacts, many samples",UPN2_044,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),7276,84,7387,"0,011371328",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"33,61","30,29"
"many samples, low freq, many artifacts",UPN2_029,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),20043,384,20489,"0,0187417639",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,"0,001",Damaging,"34,17","31,29"
"low freq, many artifacts, many samples",UPN2_030,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),21650,465,22184,"0,020961053",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"34,07","31,37"
"low freq, many artifacts, many samples",UPN2_031,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),13725,239,14002,"0,0170689901",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,34,"31,44"
many samples,UPN2_005,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),5363,136,5522,"0,0246287577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"34,18","31,07"
"low freq, many artifacts, many samples",UPN2_032,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),8010,150,8189,"0,0183172549",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"34,11","31,37"
"many samples, low freq, many artifacts",UPN2_046,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),26180,446,26735,"0,0166822517",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,"0,001",Damaging,"33,54","30,94"
"many samples, low freq, many artifacts",UPN2_033,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),16620,363,17042,"0,0213003169",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,"0,001",Damaging,"33,95","31,73"
"low freq, many artifacts, many samples",UPN2_034,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),6485,97,6596,"0,0147058824",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"34,1","31,26"
"many samples, low freq, many artifacts",UPN2_048,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),21014,320,21408,"0,0149476831",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,"0,001",Damaging,"33,41","31,09"
"many samples, low freq, many artifacts",UPN2_035,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),40441,989,41555,"0,0237997834",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,"0,001",Damaging,"34,02","31,48"
many samples,UPN2_036,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),38314,890,39363,"0,0226100653",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"34,14","31,34"
many samples,UPN2_006,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),18685,581,19333,"0,0300522423",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"34,07","31,17"
"many samples, low freq, many artifacts",UPN2_049,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),17806,196,18088,"0,0108359133",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,"0,001",Damaging,"33,49","30,83"
"low freq, many artifacts, many samples",UPN2_037,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),25193,440,25703,"0,0171186243",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"34,16","31,48"
many samples,UPN2_038,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),35725,808,36656,"0,0220427761",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"34,06","31,31"
"many samples, low freq, many artifacts",UPN2_039,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),60212,1455,61843,"0,0235273192",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,"0,001",Damaging,34,"31,45"
"many samples, low freq, many artifacts",UPN2_053,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),30313,311,30739,"0,0101174404",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,"0,001",Damaging,"33,64","30,44"
"many samples, low freq, many artifacts",UPN2_007,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),40964,848,41934,"0,020222254",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,"0,001",Damaging,"34,12","31,14"
"many samples, low freq, many artifacts",UPN2_008,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),53131,1056,54363,"0,0194249765",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,"0,001",Damaging,"34,14","31,33"
"many samples, low freq, many artifacts",UPN2_009,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),43123,722,43998,"0,0164098368",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,"0,001",Damaging,"34,16","31,08"
many samples,UPN2_010,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),32924,790,33825,"0,0233555063",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"34,09","31,36"
"many samples, low freq, many artifacts",UPN2_011,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),38184,811,39159,"0,0207104369",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,"0,001",Damaging,"34,19","31,23"
"many samples, low freq, many artifacts",UPN2_057,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),25387,272,25766,"0,0105565474",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,"0,001",Damaging,"33,65","30,76"
"many samples, low freq, many artifacts",UPN2_058,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),28019,430,28560,"0,0150560224",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,"0,001",Damaging,"33,53","31,16"
"low freq, many artifacts, many samples",UPN2_059,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),16517,337,16921,"0,0199160806",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"33,6","31,02"
"low freq, many artifacts, many samples",UPN2_012,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),18689,366,19102,"0,0191602974",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"34,17","30,94"
"low freq, many artifacts, many samples",UPN2_060,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),12189,265,12501,"0,0211983041",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"33,79","31,05"
"many samples, low freq, many artifacts",UPN2_040,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),51534,972,52686,"0,0184489238",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,"0,001",Damaging,"34,19","31,47"
"low freq, many artifacts, many samples",UPN2_013,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),11259,221,11524,"0,019177369",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"34,1","31,24"
many samples,UPN2_061,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),11211,268,11535,"0,0232336368",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"33,74","31,01"
many samples,UPN2_062,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),8663,261,8953,"0,0291522395",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"33,66","30,93"
many samples,UPN2_063,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),9699,253,9992,"0,0253202562",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"33,75","30,5"
many samples,UPN2_064,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),11798,345,12175,"0,0283367556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"33,64","30,86"
"many samples, low freq, many artifacts",UPN2_065,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),14052,308,14420,"0,0213592233",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,"0,001",Damaging,"33,69","30,81"
"low freq, many artifacts, many samples",UPN2_066,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),14463,206,14722,"0,013992664",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"33,83","30,44"
"many samples, low freq, many artifacts",UPN2_067,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),15423,320,15803,"0,0202493197",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,"0,001",Damaging,"33,67","30,41"
"many samples, low freq, many artifacts",UPN2_068,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),13057,265,13373,"0,0198160473",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,"0,001",Damaging,"33,75","31,31"
"low freq, many artifacts, many samples",UPN2_069,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),15564,326,15950,"0,0204388715",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"33,66","30,73"
"many samples, low freq, many artifacts",UPN2_070,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),10272,209,10521,"0,0198650318",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,"0,001",Damaging,"33,71","30,62"
many samples,UPN2_071,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),7362,170,7560,"0,0224867725",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"33,61","30,55"
many samples,UPN2_072,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),9257,285,9572,"0,0297743418",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"33,43","31,02"
"many samples, low freq, many artifacts",UPN2_073,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),11156,286,11475,"0,0249237473",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,"0,001",Damaging,"33,53","30,95"
"low freq, many artifacts, many samples",UPN2_074,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),8619,161,8806,"0,0182829889",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"33,86","31,19"
many samples,UPN2_075,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),13954,364,14370,"0,0253305498",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"33,57","30,71"
many samples,UPN2_076,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),13079,330,13446,"0,0245426149",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"33,67","30,89"
"many samples, low freq, many artifacts",UPN2_077,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),13996,277,14340,"0,0193165969",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,"0,001",Damaging,"33,76","30,53"
"many samples, low freq, many artifacts",UPN2_078,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),11724,291,12066,"0,0241173545",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,"0,001",Damaging,"33,65","31,44"
"low freq, many artifacts, many samples",UPN2_079,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),8074,168,8270,"0,0203143894",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"33,74","30,84"
"many samples, low freq, many artifacts",UPN2_080,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),12344,271,12648,"0,0214263125",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,"0,001",Damaging,"33,68","31,15"
"many samples, low freq, many artifacts",UPN2_081,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),16313,377,16752,"0,0225047755",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,"0,001",Damaging,"33,56","30,69"
"many samples, low freq, many artifacts",UPN2_082,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),16698,185,16949,"0,0109150982",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,"0,001",Damaging,"33,89","30,1"
"many samples, low freq, many artifacts",UPN2_083,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),16484,416,16956,"0,0245340882",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,"0,001",Damaging,"33,69","31,16"
many samples,UPN2_084,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),15202,346,15638,"0,0221255915",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"33,69","30,34"
"low freq, many artifacts, many samples",UPN2_085,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),11570,189,11800,"0,0160169492",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"33,73","31,1"
"low freq, many artifacts, many samples",UPN2_086,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),7900,117,8047,"0,01453958",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"33,71","30,79"
"low freq, many artifacts, many samples",UPN2_087,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),17721,302,18082,"0,0167016923",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"33,83","30,62"
"low freq, many artifacts",UPN2_088,4,106197443,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg1926Gly/c.5776C>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),14882,335,15284,"0,021918346",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,35",Deleterious,1,Damaging,"33,68","31,15"
"many samples, low freq, many artifacts",UPN2_001,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),15047,157,15231,"0,0103079246",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,3","34,55"
"many samples, low freq, many artifacts",UPN2_014,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),18945,231,19220,"0,0120187305",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,39","35,15"
"many samples, low freq, many artifacts",UPN2_015,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),28341,312,28707,"0,0108684293",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,4","35,19"
"many samples, low freq, many artifacts",UPN2_016,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),13304,181,13508,"0,013399467",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,4","35,29"
"many samples, low freq, many artifacts",UPN2_017,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),8654,105,8779,"0,0119603599",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,41",36
"many samples, low freq, many artifacts",UPN2_018,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),13255,167,13449,"0,0124172801",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,43","35,4"
"many samples, low freq, many artifacts",UPN2_020,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),11662,136,11818,"0,0115078694",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,43","34,97"
"many samples, low freq, many artifacts",UPN2_021,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),14822,168,15024,"0,0111821086",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,35","35,22"
"many samples, low freq, many artifacts",UPN2_022,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),21499,233,21772,"0,0107018188",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,39","34,7"
"many samples, low freq, many artifacts",UPN2_023,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),21825,245,22113,"0,0110794555",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,39","35,26"
"many samples, low freq, many artifacts",UPN2_041,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),5846,79,5942,"0,0132951868",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"34,97","35,23"
"many samples, low freq, many artifacts",UPN2_024,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),10034,113,10180,"0,0111001965",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,46","35,21"
"many samples, low freq, many artifacts",UPN2_025,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),23830,251,24130,"0,0104019892",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,43","35,51"
"many samples, low freq, many artifacts",UPN2_026,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),24409,287,24744,"0,0115987714",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,4","34,66"
"many samples, low freq, many artifacts",UPN2_027,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),27290,292,27661,"0,010556379",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,37","35,3"
"many samples, low freq, many artifacts",UPN2_042,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),34482,397,34971,"0,0113522633",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,06","35,04"
"many samples, low freq, many artifacts",UPN2_043,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),21467,299,21837,"0,013692357",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,13","35,04"
"many samples, low freq, many artifacts",UPN2_044,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),7339,100,7464,"0,013397642",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,03","34,78"
"many samples, low freq, many artifacts",UPN2_029,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),20538,262,20845,"0,0125689614",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,42","35,41"
"many samples, low freq, many artifacts",UPN2_030,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),22299,232,22575,"0,0102768549",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,37","35,42"
"many samples, low freq, many artifacts",UPN2_031,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),14049,147,14216,"0,0103404615",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,38","35,67"
"low freq, many artifacts, many samples",UPN2_005,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),5592,58,5655,"0,0102564103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,436,Tolerated,"35,29","34,69"
"many samples, low freq, many artifacts",UPN2_045,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),25708,326,26090,"0,0124952089",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,07",35
"low freq, many artifacts, many samples",UPN2_032,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),8182,83,8284,"0,0100193143",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,436,Tolerated,"35,35","35,06"
"many samples, low freq, many artifacts",UPN2_046,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),26740,299,27118,"0,0110258869",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"34,97","35,06"
"many samples, low freq, many artifacts",UPN2_033,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),17076,202,17317,"0,011664838",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,35","35,4"
"many samples, low freq, many artifacts",UPN2_034,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),6598,82,6704,"0,0122315036",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,38","35,85"
"many samples, low freq, many artifacts",UPN2_047,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),40782,481,41389,"0,0116214453",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,08","34,77"
"many samples, low freq, many artifacts",UPN2_048,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),21320,270,21672,"0,0124584718",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,03","34,67"
"many samples, low freq, many artifacts",UPN2_035,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),41793,458,42338,"0,0108177051",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,39","35,31"
"many samples, low freq, many artifacts",UPN2_036,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),39542,429,40067,"0,0107070657",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,38","34,85"
"many samples, low freq, many artifacts",UPN2_006,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),19509,242,19792,"0,0122271625",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,21","34,98"
"many samples, low freq, many artifacts",UPN2_049,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),17906,274,18245,"0,0150178131",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,02","34,95"
"many samples, low freq, many artifacts",UPN2_050,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),24057,280,24408,"0,0114716486",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,02","34,9"
"many samples, low freq, many artifacts",UPN2_037,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),25738,292,26067,"0,0112019028",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,43","35,44"
"many samples, low freq, many artifacts",UPN2_051,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),22947,279,23294,"0,0119773332",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,09","34,37"
"many samples, low freq, many artifacts",UPN2_052,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),21285,257,21590,"0,0119036591",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,05","34,47"
"many samples, low freq, many artifacts",UPN2_038,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),36787,434,37308,"0,0116328937",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,39","34,89"
"many samples, low freq, many artifacts",UPN2_039,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),62305,641,63080,"0,0101616994",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,39","35,04"
"many samples, low freq, many artifacts",UPN2_053,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),30557,396,31048,"0,0127544447",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,03","34,51"
"many samples, low freq, many artifacts",UPN2_054,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),21520,240,21832,"0,0109930377",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,35,"34,45"
"many samples, low freq, many artifacts",UPN2_055,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),31776,397,32277,"0,01229978",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,07","35,04"
"many samples, low freq, many artifacts",UPN2_057,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),25645,300,26033,"0,0115238351",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,02","34,92"
"many samples, low freq, many artifacts",UPN2_058,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),28516,359,28949,"0,0124011192",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,03","34,93"
"many samples, low freq, many artifacts",UPN2_040,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),52768,644,53513,"0,0120344589",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,41","35,1"
"many samples, low freq, many artifacts",UPN2_092,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),7212,80,7299,"0,0109604055",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,45","35,6"
"many samples, low freq, many artifacts",UPN2_093,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),8476,90,8578,"0,0104919562",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,49","35,23"
"many samples, low freq, many artifacts",UPN2_080,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),12764,137,12924,"0,0106004333",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,01","34,42"
"low freq, many artifacts, many samples",UPN2_083,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),17049,174,17248,"0,0100881262",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,436,Tolerated,"35,05","34,29"
"many samples, low freq, many artifacts",UPN2_086,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),8049,89,8156,"0,0109122119",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,08","34,98"
"many samples, low freq, many artifacts",UPN2_095,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),13308,142,13477,"0,0105364695",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,41","35,55"
"many samples, low freq, many artifacts",UPN2_101,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),12518,130,12653,"0,0102742433",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,38","34,88"
"many samples, low freq, many artifacts",UPN2_106,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),20745,231,20994,"0,0110031438",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,43","35,77"
"many samples, low freq, many artifacts",UPN2_107,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),24826,280,25139,"0,0111380723",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,41","35,38"
"many samples, low freq, many artifacts",UPN2_111,4,106197468,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys1934Arg/c.5801A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),18384,190,18593,"0,0102188996",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,05",Neutral,"0,436",Tolerated,"35,41","35,08"
"low freq, many artifacts, many samples",UPN2_004,4,106197472,TG,T,frameshift_variant(HIGH||ggc/|p.Gly1936fs/c.5807delG|2002|TET2|protein_coding|CODING|ENST00000380013|11|T|INFO_REALIGN_3_PRIME),2437,44,2491,"0,0176635889",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,18",NA
"many samples, strandbias",UPN2_001,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),12834,2265,15133,"0,1496729003",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,73","31,61"
"many samples, strandbias",UPN2_014,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),17321,1732,19108,"0,0906426628",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,95","31,59"
"many samples, strandbias",UPN2_015,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),26368,2128,28574,"0,0744732974",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"33,13","31,74"
"many samples, strandbias",UPN2_016,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),12258,1150,13451,"0,0854955022",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"33,14","31,83"
"many samples, strandbias",UPN2_017,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),7882,842,8743,"0,0963056159",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,9","31,63"
"many samples, strandbias",UPN2_018,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),12269,1085,13392,"0,0810185185",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"33,07","31,59"
"many samples, strandbias",UPN2_019,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),14661,1541,16236,"0,09491254",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"33,1","31,73"
"many samples, strandbias",UPN2_020,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),10574,1143,11758,"0,0972104099",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,8","31,63"
"many samples, strandbias",UPN2_021,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),13490,1429,14959,"0,0955277759",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"33,09","31,76"
"many samples, strandbias",UPN2_002,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),15438,2790,18271,"0,1527010016",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,6","31,65"
"many samples, strandbias",UPN2_003,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3045,531,3587,"0,1480345693",0,1,0,0,1,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,56","31,63"
"many samples, strandbias",UPN2_022,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),19668,1946,21692,"0,0897104923",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"33,05","31,69"
"many samples, strandbias",UPN2_023,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),19872,2095,22041,"0,0950501338",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,97","31,69"
"many samples, strandbias",UPN2_041,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5687,218,5929,"0,0367684264",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,75","31,79"
"many samples, strandbias",UPN2_024,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),9252,859,10133,"0,0847725254",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,85","31,64"
"many samples, strandbias",UPN2_025,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),21736,2232,24033,"0,0928723006",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"33,06","31,6"
"many samples, strandbias",UPN2_026,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),22312,2255,24620,"0,0915922015",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,96","31,64"
"many samples, strandbias",UPN2_004,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2205,260,2472,"0,1051779935",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"33,39","31,59"
"many samples, strandbias",UPN2_027,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),24728,2722,27533,"0,0988631824",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"33,02","31,69"
"many samples, strandbias",UPN2_089,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),12986,542,13548,"0,0400059049",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,61","31,74"
"many samples, strandbias",UPN2_042,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),32911,1768,34813,"0,0507856261",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,61","31,53"
"many samples, strandbias",UPN2_028,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),17769,1738,19580,"0,0887640449",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"33,12","31,68"
"many samples, strandbias",UPN2_043,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),20431,1223,21722,"0,0563023663",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,53","31,57"
"many samples, strandbias",UPN2_044,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6973,439,7438,"0,0590212423",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,58","31,43"
"many samples, strandbias",UPN2_029,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),18675,1980,20730,"0,0955137482",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,84","31,62"
"many samples, strandbias",UPN2_030,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),20404,1990,22468,"0,0885704113",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"33,02","31,7"
"many samples, strandbias",UPN2_031,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),12890,1231,14160,"0,0869350282",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,99","31,64"
"many samples, strandbias",UPN2_005,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4704,887,5609,"0,1581387057",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,52","31,63"
"many samples, strandbias",UPN2_045,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),24774,1117,25962,"0,0430244203",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,37","31,71"
"many samples, strandbias",UPN2_032,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),7541,694,8252,"0,084100824",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,89","31,55"
"many samples, strandbias",UPN2_046,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),25214,1676,26969,"0,0621454262",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,85","31,61"
"many samples, strandbias",UPN2_033,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),15692,1502,17248,"0,0870825603",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"33,14","31,71"
"many samples, strandbias",UPN2_034,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6100,536,6664,"0,0804321729",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,9","31,69"
"many samples, strandbias",UPN2_047,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),38702,2356,41206,"0,0571761394",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,55","31,56"
"many samples, strandbias",UPN2_048,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),20401,1113,21588,"0,0515564202",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,88","31,46"
"many samples, strandbias",UPN2_035,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),38122,3971,42190,"0,0941218298",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"33,05","31,65"
"many samples, strandbias",UPN2_036,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),35750,3957,39823,"0,0993646887",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,93","31,67"
"many samples, strandbias",UPN2_006,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),16920,2682,19656,"0,1364468864",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,86","31,68"
"many samples, strandbias",UPN2_049,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),17114,979,18146,"0,053951284",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,7","31,55"
"many samples, strandbias",UPN2_050,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),23441,799,24329,"0,0328414649",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,58","31,49"
"many samples, strandbias",UPN2_037,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),23538,2343,25954,"0,0902751021",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,87","31,54"
"many samples, strandbias",UPN2_051,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),22106,998,23197,"0,0430228047",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,78","31,54"
"many samples, strandbias",UPN2_052,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),20670,781,21529,"0,0362766501",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,51","31,66"
"many samples, strandbias",UPN2_038,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),33465,3540,37115,"0,0953792267",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"33,01","31,65"
"many samples, strandbias",UPN2_039,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),56974,5555,62713,"0,0885781257",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"33,1","31,75"
"many samples, strandbias",UPN2_053,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),28930,1848,30877,"0,0598503741",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,66","31,56"
"many samples, strandbias",UPN2_054,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),20753,939,21759,"0,0431545567",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,73","31,54"
"many samples, strandbias",UPN2_007,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),36358,5985,42449,"0,1409927207",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,7","31,51"
"many samples, strandbias",UPN2_008,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),47035,7642,54840,"0,1393508388",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,65","31,63"
"many samples, strandbias",UPN2_009,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),38620,5593,44340,"0,1261389265",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,6","31,63"
"many samples, strandbias",UPN2_010,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),29602,4542,34236,"0,1326673677",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,77","31,69"
"many samples, strandbias",UPN2_011,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),33633,5783,39533,"0,1462828523",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,61","31,58"
"many samples, strandbias",UPN2_055,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),30477,1560,32160,"0,0485074627",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,61","31,44"
"inspected, bad alignment, strandbias, many samples",UPN2_056,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),9414,458,9919,"0,0461740095",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,83","31,65"
"many samples, strandbias",UPN2_090,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),11332,366,11716,"0,0312393308",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,65","31,59"
"many samples, strandbias",UPN2_057,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),24180,1594,25876,"0,061601484",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,66","31,57"
"many samples, strandbias",UPN2_058,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),26600,2135,28842,"0,0740239928",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,74","31,51"
"many samples, strandbias",UPN2_059,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),15474,1624,17132,"0,0947933691",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,6","31,67"
"many samples, strandbias",UPN2_012,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),16562,2739,19346,"0,1415796547",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,69","31,66"
"many samples, strandbias",UPN2_060,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),11142,1458,12630,"0,1154394299",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,51","31,6"
"many samples, strandbias",UPN2_040,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),47883,5219,53274,"0,0979652363",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,83","31,73"
"many samples, strandbias",UPN2_013,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),9945,1655,11634,"0,1422554581",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,59","31,55"
"many samples, strandbias",UPN2_091,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),10885,497,11403,"0,0435850215",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,78","31,91"
"many samples, strandbias",UPN2_092,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6975,287,7273,"0,0394610202",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,67","31,49"
many samples,UPN2_093,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),8229,308,8554,"0,0360065466",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,84","31,63"
"many samples, strandbias",UPN2_061,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),10281,1409,11717,"0,1202526244",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,58","31,6"
"many samples, strandbias",UPN2_062,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),8134,981,9139,"0,10734216",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,71","31,61"
"many samples, strandbias",UPN2_063,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),8825,1286,10135,"0,1268870252",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,52","31,55"
"many samples, strandbias",UPN2_064,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),10751,1572,12375,"0,127030303",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,64","31,6"
"many samples, strandbias",UPN2_065,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),13015,1485,14535,"0,1021671827",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,58","31,63"
"many samples, strandbias",UPN2_066,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),13088,1718,14838,"0,1157837984",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,33","31,54"
"many samples, strandbias",UPN2_067,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),14103,1826,15972,"0,1143250689",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,53","31,56"
"many samples, strandbias",UPN2_068,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),12077,1408,13516,"0,1041728322",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,48","31,58"
"many samples, strandbias",UPN2_069,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),14325,1779,16147,"0,1101752648",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,55","31,54"
"many samples, strandbias",UPN2_070,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),9412,1214,10652,"0,1139692077",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,54","31,57"
"many samples, strandbias",UPN2_071,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6787,864,7672,"0,1126173097",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,7","31,49"
"many samples, strandbias",UPN2_072,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),8773,1006,9804,"0,1026111791",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,71","31,62"
"many samples, strandbias",UPN2_073,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),10312,1286,11617,"0,1106998364",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,77","31,46"
"many samples, strandbias",UPN2_074,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),7649,1185,8867,"0,1336415924",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,47","31,56"
"many samples, strandbias",UPN2_075,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),12810,1698,14546,"0,1167331225",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,63","31,52"
"many samples, strandbias",UPN2_076,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),12079,1551,13663,"0,113518261",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,62","31,61"
"many samples, strandbias",UPN2_077,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),12794,1629,14461,"0,1126478114",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,55","31,55"
"many samples, strandbias",UPN2_078,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),10885,1343,12261,"0,1095342957",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,7","31,61"
"many samples, strandbias",UPN2_079,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),7355,987,8371,"0,1179070601",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,51","31,49"
"many samples, strandbias",UPN2_080,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),11343,1490,12867,"0,1158001088",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,63","31,7"
"many samples, strandbias",UPN2_081,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),15291,1719,17052,"0,1008092892",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,66","31,47"
"many samples, strandbias",UPN2_082,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),15052,1942,17044,"0,1139403896",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,3","31,41"
"many samples, strandbias",UPN2_083,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),14954,2116,17125,"0,1235620438",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,57","31,52"
"many samples, strandbias",UPN2_084,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),14190,1656,15887,"0,1042361679",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,58","31,59"
"many samples, strandbias",UPN2_085,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),10608,1253,11891,"0,1053738121",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,44","31,56"
"many samples, strandbias",UPN2_086,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),7202,889,8111,"0,1096042412",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,4","31,49"
"many samples, strandbias",UPN2_087,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),16030,2127,18216,"0,1167654809",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,38","31,52"
"many samples, strandbias",UPN2_088,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),13570,1884,15502,"0,1215327055",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,6","31,49"
"many samples, strandbias",UPN2_094,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),13841,457,14320,"0,0319134078",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,63","31,55"
"many samples, strandbias",UPN2_095,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),12882,553,13447,"0,0411244144",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,8","31,78"
"many samples, strandbias",UPN2_096,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),13786,481,14292,"0,0336551917",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,62","31,48"
"many samples, strandbias",UPN2_097,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),15063,629,15717,"0,0400203601",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,74","31,64"
"many samples, strandbias",UPN2_098,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),13860,592,14467,"0,0409207161",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,83","31,8"
"many samples, strandbias",UPN2_099,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),7446,307,7765,"0,0395363812",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,71","31,78"
"many samples, strandbias",UPN2_100,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),12394,390,12798,"0,0304735115",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,79","31,72"
"many samples, strandbias",UPN2_101,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),12202,363,12590,"0,0288324067",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,8","31,93"
"many samples, strandbias",UPN2_102,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),14214,508,14745,"0,0344523567",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,76","31,71"
"many samples, strandbias",UPN2_103,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),13769,516,14304,"0,0360738255",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,91","31,77"
"many samples, strandbias",UPN2_104,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),15651,654,16326,"0,0400588019",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,64","31,68"
"many samples, strandbias",UPN2_105,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),13828,551,14399,"0,0382665463",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,7","31,71"
"many samples, strandbias",UPN2_106,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),20317,578,20926,"0,0276211412",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,65","31,76"
"many samples, strandbias",UPN2_107,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),24233,797,25069,"0,0317922534",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,72","31,88"
"many samples, strandbias",UPN2_108,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),20694,592,21318,"0,0277699597",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,82","31,7"
"many samples, strandbias",UPN2_109,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),20701,577,21307,"0,0270803022",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,74","31,48"
"many samples, strandbias",UPN2_110,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),19247,462,19731,"0,0234149308",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,64","31,77"
"many samples, strandbias",UPN2_111,4,106197497,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser1944Pro/c.5830T>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),17896,623,18542,"0,033599396",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,"0,04",Damaging,"32,84","31,61"
"low bq, low freq, many artifacts, many samples",UPN2_001,4,106197502,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1945Gln/c.5835T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3834,40,3883,"0,0103013134",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,4,Damaging,"34,36","18,08"
"low bq, low freq, many artifacts, many samples",UPN2_020,4,106197502,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1945Gln/c.5835T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3160,34,3202,"0,0106183635",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,4,Damaging,"34,48","23,15"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106197502,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1945Gln/c.5835T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),10144,130,10322,"0,0125944584",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,4,Damaging,"33,77","19,46"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106197502,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1945Gln/c.5835T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5791,67,5893,"0,0113694213",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,4,Damaging,"33,57","18,48"
"low bq, low freq, many artifacts, many samples",UPN2_044,4,106197502,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1945Gln/c.5835T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2334,37,2378,"0,0155592935",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,4,Damaging,"33,59","19,24"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106197502,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1945Gln/c.5835T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),11695,131,11883,"0,0110241522",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,4,Damaging,"33,66","19,71"
"low bq, low freq, many artifacts, many samples",UPN2_048,4,106197502,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1945Gln/c.5835T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),8324,101,8463,"0,0119343023",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,4,Damaging,"33,71","19,94"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106197502,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1945Gln/c.5835T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6017,74,6135,"0,0120619397",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,4,Damaging,"33,57","18,49"
"low bq, low freq, many artifacts, many samples",UPN2_050,4,106197502,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1945Gln/c.5835T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7452,85,7576,"0,011219641",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,4,Damaging,"33,68","21,09"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106197502,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1945Gln/c.5835T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),8389,97,8533,"0,0113676315",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,4,Damaging,"33,66","20,32"
"low bq, low freq, many artifacts, many samples",UPN2_052,4,106197502,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1945Gln/c.5835T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6017,65,6115,"0,0106295993",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,4,Damaging,"33,44","19,85"
"low bq, low freq, many artifacts, many samples",UPN2_053,4,106197502,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1945Gln/c.5835T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9834,106,9983,"0,0106180507",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,4,Damaging,"33,52","19,79"
"low bq, low freq, many artifacts, many samples",UPN2_054,4,106197502,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1945Gln/c.5835T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7572,95,7699,"0,0123392648",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,4,Damaging,"33,56","19,99"
"low bq, low freq, many artifacts, many samples",UPN2_055,4,106197502,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1945Gln/c.5835T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9942,136,10145,"0,0134056185",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,4,Damaging,"33,56","20,11"
"low bq, low freq, many artifacts, many samples",UPN2_056,4,106197502,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1945Gln/c.5835T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3627,41,3689,"0,0111141231",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,4,Damaging,"33,71","20,15"
"low bq, low freq, many artifacts, many samples",UPN2_057,4,106197502,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1945Gln/c.5835T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7898,94,8038,"0,0116944514",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,4,Damaging,"33,72","19,5"
"low bq, low freq, many artifacts",UPN2_058,4,106197502,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1945Gln/c.5835T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9570,112,9718,"0,0115250051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,4,Damaging,"33,73","18,77"
"low freq, many artifacts",UPN2_036,4,106197505,C,CA,frameshift_variant(HIGH||gtg/Agtg|p.Val1949fs/c.5844dupA|2002|TET2|protein_coding|CODING|ENST00000380013|11|CA|INFO_REALIGN_3_PRIME),12415,127,12459,"0,0101934345",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,31",NA
"low freq, many artifacts, many samples",UPN2_032,4,106197505,CA,C,frameshift_variant(HIGH||aaa/|p.Val1949fs/c.5844delA|2002|TET2|protein_coding|CODING|ENST00000380013|11|C|INFO_REALIGN_3_PRIME),2557,27,2597,"0,0103966115",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,96",NA
"low freq, many artifacts, many samples",UPN2_010,4,106197505,CA,C,frameshift_variant(HIGH||aaa/|p.Val1949fs/c.5844delA|2002|TET2|protein_coding|CODING|ENST00000380013|11|C|INFO_REALIGN_3_PRIME),9452,99,9600,"0,0103125",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,74",NA
"low freq, many artifacts, many samples",UPN2_061,4,106197505,CA,C,frameshift_variant(HIGH||aaa/|p.Val1949fs/c.5844delA|2002|TET2|protein_coding|CODING|ENST00000380013|11|C|INFO_REALIGN_3_PRIME),3183,35,3240,"0,0108024691",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,9",NA
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106197513,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val1949Glu/c.5846T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),10126,128,10316,"0,01240791",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,26",Neutral,543,Tolerated,"33,82","17,79"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106197513,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val1949Glu/c.5846T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5782,78,5888,"0,0132472826",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,26",Neutral,543,Tolerated,"33,74","18,78"
"low bq, low freq, many artifacts, many samples",UPN2_044,4,106197513,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val1949Glu/c.5846T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2342,27,2379,"0,0113493064",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,26",Neutral,543,Tolerated,"33,72","16,81"
"low bq, low freq, many artifacts, many samples",UPN2_045,4,106197513,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val1949Glu/c.5846T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5573,57,5658,"0,0100742312",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,26",Neutral,543,Tolerated,"33,85","19,26"
"low bq, low freq, many artifacts, many samples",UPN2_046,4,106197513,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val1949Glu/c.5846T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9870,120,10036,"0,011956955",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,26",Neutral,543,Tolerated,"33,9","19,67"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106197513,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val1949Glu/c.5846T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),11682,157,11880,"0,0132154882",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,26",Neutral,543,Tolerated,"33,81","20,41"
"low bq, low freq, many artifacts, many samples",UPN2_048,4,106197513,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val1949Glu/c.5846T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),8304,119,8462,"0,0140628693",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,26",Neutral,543,Tolerated,"33,75","21,3"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106197513,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val1949Glu/c.5846T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6047,64,6132,"0,0104370515",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,26",Neutral,543,Tolerated,"33,71","20,41"
"low bq, low freq, many artifacts, many samples",UPN2_050,4,106197513,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val1949Glu/c.5846T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7433,87,7568,"0,0114957717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,26",Neutral,543,Tolerated,"33,73","17,92"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106197513,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val1949Glu/c.5846T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),8393,107,8532,"0,012541022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,26",Neutral,543,Tolerated,"33,82","19,09"
"low bq, low freq, many artifacts, many samples",UPN2_052,4,106197513,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val1949Glu/c.5846T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6000,87,6115,"0,0142273099",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,26",Neutral,543,Tolerated,"33,73","18,79"
"low bq, low freq, many artifacts, many samples",UPN2_053,4,106197513,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val1949Glu/c.5846T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9821,119,9977,"0,0119274331",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,26",Neutral,543,Tolerated,"33,76","18,5"
"low bq, low freq, many artifacts, many samples",UPN2_054,4,106197513,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val1949Glu/c.5846T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7549,107,7696,"0,0139033264",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,26",Neutral,543,Tolerated,"33,77","18,44"
"low bq, low freq, many artifacts, many samples",UPN2_057,4,106197513,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val1949Glu/c.5846T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7903,98,8034,"0,0121981578",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,26",Neutral,543,Tolerated,"33,77","16,96"
"low bq, low freq, many artifacts, many samples",UPN2_058,4,106197513,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val1949Glu/c.5846T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9531,126,9707,"0,0129803235",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,26",Neutral,543,Tolerated,"33,98","19,97"
"low bq, low freq, many artifacts, many samples",UPN2_012,4,106197513,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val1949Glu/c.5846T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4718,54,4788,"0,0112781955",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,26",Neutral,543,Tolerated,"34,53","18,13"
"low bq, low freq, many artifacts, many samples",UPN2_013,4,106197513,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val1949Glu/c.5846T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2848,32,2895,"0,0110535406",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,26",Neutral,543,Tolerated,"34,37","18,69"
"low bq, low freq, many artifacts",UPN2_072,4,106197513,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val1949Glu/c.5846T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3383,37,3436,"0,0107683353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,26",Neutral,543,Tolerated,"33,72","19,05"
"inspected, bad alignment, many artifacts",UPN2_056,4,106197516,A,G,missense_variant(MODERATE|MISSENSE|aAa/aGa|p.Lys1950Arg/c.5849A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),3640,38,3686,"0,0103092784",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,18",Neutral,"0,016",Damaging,"31,87","34,68"
"inspected, bad alignment, many artifacts",UPN2_041,4,106197521,G,A,missense_variant(MODERATE|MISSENSE|Gag/Aag|p.Glu1952Lys/c.5854G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1995,34,2031,"0,0167405219",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,"0,048",Damaging,"33,76","29,82"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106197531,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1955Ala/c.5864A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),10138,104,10307,"0,0100902299",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,19",Neutral,58,Tolerated,"28,1","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_044,4,106197531,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1955Ala/c.5864A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2330,26,2375,"0,0109473684",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,19",Neutral,58,Tolerated,"28,01","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_045,4,106197531,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1955Ala/c.5864A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5553,61,5651,"0,0107945496",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,19",Neutral,58,Tolerated,"27,94","15,66"
"low bq, low freq, many artifacts, many samples",UPN2_058,4,106197531,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1955Ala/c.5864A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),9541,100,9697,"0,0103124678",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,19",Neutral,58,Tolerated,"28,27","14,53"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_059,4,106197531,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1955Ala/c.5864A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5048,113,5188,"0,0217810332",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,19",Neutral,58,Tolerated,"26,41","14,74"
"low bq, bad alignment, many samples",UPN2_060,4,106197531,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1955Ala/c.5864A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3192,81,3285,"0,0246575342",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,19",Neutral,58,Tolerated,"26,28","14,26"
"low bq, bad alignment, many samples",UPN2_061,4,106197531,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1955Ala/c.5864A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3125,92,3230,"0,0284829721",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,19",Neutral,58,Tolerated,"26,19","15,11"
"low bq, bad alignment, many samples",UPN2_062,4,106197531,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1955Ala/c.5864A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2868,77,2959,"0,0260223048",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,19",Neutral,58,Tolerated,"25,8","15,06"
"low bq, bad alignment, many samples",UPN2_063,4,106197531,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1955Ala/c.5864A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2718,72,2802,"0,0256959315",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,19",Neutral,58,Tolerated,"26,13","15,25"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,4,106197531,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1955Ala/c.5864A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3552,74,3646,"0,020296215",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,19",Neutral,58,Tolerated,"26,2","14,95"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_065,4,106197531,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1955Ala/c.5864A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4015,89,4123,"0,0215862236",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,19",Neutral,58,Tolerated,"26,51","14,44"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_066,4,106197531,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1955Ala/c.5864A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3025,56,3095,"0,0180936995",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,19",Neutral,58,Tolerated,"26,51","14,89"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_067,4,106197531,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1955Ala/c.5864A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3982,87,4086,"0,0212922173",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,19",Neutral,58,Tolerated,"26,43","14,87"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_068,4,106197531,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1955Ala/c.5864A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3424,74,3518,"0,0210346788",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,19",Neutral,58,Tolerated,"26,05","14,19"
"low bq, bad alignment, many samples",UPN2_069,4,106197531,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1955Ala/c.5864A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4303,110,4431,"0,0248250959",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,19",Neutral,58,Tolerated,"26,32","14,56"
"low bq, bad alignment, many samples",UPN2_070,4,106197531,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1955Ala/c.5864A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2933,85,3033,"0,0280250577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,19",Neutral,58,Tolerated,"25,98","14,94"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,4,106197531,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1955Ala/c.5864A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2365,49,2424,"0,0202145215",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,19",Neutral,58,Tolerated,"26,35","14,41"
"low bq, bad alignment, many samples",UPN2_072,4,106197531,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1955Ala/c.5864A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3317,84,3417,"0,0245829675",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,19",Neutral,58,Tolerated,"26,46",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,4,106197531,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1955Ala/c.5864A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3659,71,3743,"0,0189687417",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,19",Neutral,58,Tolerated,"26,19","14,56"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,4,106197531,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1955Ala/c.5864A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1981,44,2036,"0,021611002",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,19",Neutral,58,Tolerated,"26,07",14
"low bq, bad alignment, many samples",UPN2_075,4,106197531,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1955Ala/c.5864A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4080,99,4202,"0,0235602094",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,19",Neutral,58,Tolerated,"26,25","14,43"
"low bq, bad alignment, many samples",UPN2_076,4,106197531,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1955Ala/c.5864A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4103,102,4227,"0,0241305891",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,19",Neutral,58,Tolerated,"25,87","14,86"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,4,106197531,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1955Ala/c.5864A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3706,83,3799,"0,0218478547",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,19",Neutral,58,Tolerated,"25,94","14,86"
"low bq, bad alignment, many samples",UPN2_078,4,106197531,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1955Ala/c.5864A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3617,97,3736,"0,0259635974",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,19",Neutral,58,Tolerated,"25,88","14,63"
"low bq, bad alignment, many samples",UPN2_079,4,106197531,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1955Ala/c.5864A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2076,48,2134,"0,0224929709",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,19",Neutral,58,Tolerated,"26,1","14,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,4,106197531,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1955Ala/c.5864A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3571,80,3661,"0,021851953",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,19",Neutral,58,Tolerated,"26,43","14,41"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_081,4,106197531,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1955Ala/c.5864A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5218,115,5364,"0,0214392245",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,19",Neutral,58,Tolerated,"26,45","14,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_082,4,106197531,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1955Ala/c.5864A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3192,68,3273,"0,0207760464",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,19",Neutral,58,Tolerated,"26,32","14,21"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,4,106197531,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1955Ala/c.5864A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4653,103,4771,"0,0215887655",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,19",Neutral,58,Tolerated,"26,14","14,57"
"low bq, bad alignment, many samples",UPN2_084,4,106197531,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1955Ala/c.5864A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4379,101,4503,"0,0224294915",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,19",Neutral,58,Tolerated,"26,27","14,58"
"low bq, bad alignment, many samples",UPN2_085,4,106197531,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1955Ala/c.5864A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2732,74,2816,"0,0262784091",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,19",Neutral,58,Tolerated,"26,26","14,61"
"low bq, bad alignment, many samples",UPN2_086,4,106197531,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1955Ala/c.5864A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1819,54,1879,"0,0287386908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,19",Neutral,58,Tolerated,"26,32",15
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_087,4,106197531,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1955Ala/c.5864A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4129,85,4238,"0,0200566305",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,19",Neutral,58,Tolerated,"25,92",15
"low bq, bad alignment",UPN2_088,4,106197531,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1955Ala/c.5864A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4149,103,4278,"0,0240766713",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,19",Neutral,58,Tolerated,"26,51","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106197538,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1957Gln/c.5871T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),10126,125,10304,"0,0121312112",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,81",Neutral,377,Tolerated,"33,5","19,51"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106197538,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1957Gln/c.5871T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5778,63,5880,"0,0107142857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,81",Neutral,377,Tolerated,"33,51","19,25"
"low bq, low freq, many artifacts, many samples",UPN2_045,4,106197538,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1957Gln/c.5871T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5544,65,5651,"0,011502389",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,81",Neutral,377,Tolerated,"33,68","20,11"
"low bq, low freq, many artifacts, many samples",UPN2_046,4,106197538,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1957Gln/c.5871T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9855,119,10026,"0,0118691402",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,81",Neutral,377,Tolerated,"33,63","18,21"
"low bq, low freq, many artifacts, many samples",UPN2_033,4,106197538,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1957Gln/c.5871T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6318,66,6399,"0,0103141116",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,81",Neutral,377,Tolerated,"34,39","17,21"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106197538,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1957Gln/c.5871T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),11678,126,11858,"0,0106257379",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,81",Neutral,377,Tolerated,"33,57","18,56"
"low bq, low freq, many artifacts, many samples",UPN2_048,4,106197538,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1957Gln/c.5871T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),8311,97,8451,"0,0114779316",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,81",Neutral,377,Tolerated,"33,54","16,99"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106197538,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1957Gln/c.5871T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6009,75,6118,"0,0122589081",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,81",Neutral,377,Tolerated,"33,51","18,12"
"low bq, low freq, many artifacts, many samples",UPN2_050,4,106197538,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1957Gln/c.5871T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7410,91,7559,"0,0120386294",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,81",Neutral,377,Tolerated,"33,55","21,45"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106197538,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1957Gln/c.5871T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),8369,105,8521,"0,0123224974",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,81",Neutral,377,Tolerated,"33,57","17,36"
"low bq, low freq, many artifacts, many samples",UPN2_052,4,106197538,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1957Gln/c.5871T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5981,89,6108,"0,0145710544",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,81",Neutral,377,Tolerated,"33,35","17,98"
"low bq, low freq, many artifacts, many samples",UPN2_053,4,106197538,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1957Gln/c.5871T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9810,109,9962,"0,010941578",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,81",Neutral,377,Tolerated,"33,53","16,59"
"low bq, low freq, many artifacts, many samples",UPN2_054,4,106197538,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1957Gln/c.5871T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7550,87,7678,"0,0113310758",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,81",Neutral,377,Tolerated,"33,56","18,82"
"low bq, low freq, many artifacts, many samples",UPN2_055,4,106197538,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1957Gln/c.5871T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9941,128,10132,"0,0126332412",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,81",Neutral,377,Tolerated,"33,53","17,66"
"low bq, low freq, many artifacts, many samples",UPN2_056,4,106197538,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1957Gln/c.5871T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3599,55,3682,"0,0149375339",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,81",Neutral,377,Tolerated,"33,67","19,8"
"low bq, low freq, many artifacts, many samples",UPN2_057,4,106197538,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1957Gln/c.5871T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7884,96,8016,"0,0119760479",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,81",Neutral,377,Tolerated,"33,54","18,16"
"low bq, low freq, many artifacts, many samples",UPN2_058,4,106197538,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1957Gln/c.5871T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9538,110,9687,"0,0113554248",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,81",Neutral,377,Tolerated,"33,58","16,98"
"low bq, low freq, many artifacts",UPN2_012,4,106197538,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His1957Gln/c.5871T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4703,58,4781,"0,0121313533",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,81",Neutral,377,Tolerated,34,"20,29"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_059,4,106197542,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1959Pro/c.5875A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5063,78,5191,"0,0150260065",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,08",Neutral,1,Tolerated,"24,84","15,91"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_060,4,106197542,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1959Pro/c.5875A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3213,39,3281,"0,0118866199",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,08",Neutral,1,Tolerated,"24,99","14,74"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,4,106197542,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1959Pro/c.5875A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3149,52,3228,"0,0161090458",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,08",Neutral,1,Tolerated,"24,76","14,73"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,4,106197542,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1959Pro/c.5875A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2879,47,2955,"0,0159052453",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,08",Neutral,1,Tolerated,"24,35","14,81"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,4,106197542,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1959Pro/c.5875A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2754,35,2798,"0,012508935",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,08",Neutral,1,Tolerated,"24,43","15,09"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,4,106197542,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1959Pro/c.5875A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3568,42,3642,"0,0115321252",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,08",Neutral,1,Tolerated,"24,67","15,95"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_065,4,106197542,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1959Pro/c.5875A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4031,53,4119,"0,0128672008",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,08",Neutral,1,Tolerated,"25,21","15,51"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_066,4,106197542,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1959Pro/c.5875A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3035,38,3091,"0,0122937561",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,08",Neutral,1,Tolerated,"25,01","15,24"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_067,4,106197542,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1959Pro/c.5875A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3991,45,4079,"0,0110321157",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,08",Neutral,1,Tolerated,"25,21","15,04"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_068,4,106197542,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1959Pro/c.5875A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3432,51,3512,"0,0145216401",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,08",Neutral,1,Tolerated,"24,44","14,75"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_069,4,106197542,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1959Pro/c.5875A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4318,72,4425,"0,0162711864",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,08",Neutral,1,Tolerated,"24,66","14,79"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_070,4,106197542,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1959Pro/c.5875A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2942,42,3029,"0,0138659624",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,08",Neutral,1,Tolerated,"24,45","14,86"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,4,106197542,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1959Pro/c.5875A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2360,39,2421,"0,0161090458",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,08",Neutral,1,Tolerated,"24,77","15,67"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,4,106197542,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1959Pro/c.5875A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3345,39,3412,"0,0114302462",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,08",Neutral,1,Tolerated,"24,88","14,36"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,4,106197542,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1959Pro/c.5875A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3669,48,3740,"0,0128342246",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,08",Neutral,1,Tolerated,"25,17","16,04"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,4,106197542,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1959Pro/c.5875A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1993,28,2034,"0,0137659784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,08",Neutral,1,Tolerated,"24,75","14,25"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_075,4,106197542,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1959Pro/c.5875A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4122,43,4194,"0,010252742",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,08",Neutral,1,Tolerated,"24,88","14,51"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,4,106197542,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1959Pro/c.5875A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4136,53,4223,"0,0125503197",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,08",Neutral,1,Tolerated,"24,05","16,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,4,106197542,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1959Pro/c.5875A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3714,56,3797,"0,0147484856",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,08",Neutral,1,Tolerated,"24,54",15
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,4,106197542,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1959Pro/c.5875A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3670,41,3732,"0,0109860665",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,08",Neutral,1,Tolerated,"24,02","14,17"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,4,106197542,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1959Pro/c.5875A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3581,40,3661,"0,0109259765",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,08",Neutral,1,Tolerated,"24,74","14,18"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_081,4,106197542,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1959Pro/c.5875A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5263,58,5360,"0,0108208955",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,08",Neutral,1,Tolerated,"25,13","15,83"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_082,4,106197542,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1959Pro/c.5875A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3205,37,3271,"0,0113115255",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,08",Neutral,1,Tolerated,"25,1","17,16"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,4,106197542,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1959Pro/c.5875A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4669,50,4762,"0,01049979",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,08",Neutral,1,Tolerated,"24,41","15,38"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,4,106197542,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1959Pro/c.5875A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4415,56,4498,"0,0124499778",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,08",Neutral,1,Tolerated,"24,08","15,96"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_085,4,106197542,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1959Pro/c.5875A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2754,36,2816,"0,0127840909",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,08",Neutral,1,Tolerated,"24,51","14,78"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,4,106197542,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1959Pro/c.5875A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1845,23,1878,"0,0122470714",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,08",Neutral,1,Tolerated,"24,66","14,61"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_087,4,106197542,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1959Pro/c.5875A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4142,56,4235,"0,0132231405",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,08",Neutral,1,Tolerated,"24,72","14,45"
"low bq, bad alignment, low freq, many artifacts",UPN2_088,4,106197542,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1959Pro/c.5875A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4188,61,4274,"0,0142723444",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,08",Neutral,1,Tolerated,"25,03","14,11"
"low bq, low freq, many artifacts, many samples",UPN2_041,4,106197545,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser1960Thr/c.5878T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1983,27,2027,"0,0133201776",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,105,Tolerated,"32,97","19,56"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106197545,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser1960Thr/c.5878T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),10123,115,10296,"0,0111693862",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,105,Tolerated,"33,07","19,35"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106197545,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser1960Thr/c.5878T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5763,74,5874,"0,012597889",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,105,Tolerated,"33,18","17,92"
"low bq, low freq, many artifacts, many samples",UPN2_044,4,106197545,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser1960Thr/c.5878T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2338,27,2371,"0,0113876002",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,105,Tolerated,"32,93","17,59"
"low bq, low freq, many artifacts, many samples",UPN2_045,4,106197545,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser1960Thr/c.5878T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5564,62,5651,"0,0109715095",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,105,Tolerated,"33,11","18,11"
"low bq, low freq, many artifacts, many samples",UPN2_046,4,106197545,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser1960Thr/c.5878T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9845,110,10019,"0,0109791396",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,105,Tolerated,"33,05","18,45"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106197545,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser1960Thr/c.5878T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),11662,131,11854,"0,011051122",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,105,Tolerated,"33,18","18,77"
"low bq, low freq, many artifacts, many samples",UPN2_048,4,106197545,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser1960Thr/c.5878T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),8301,97,8443,"0,0114888073",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,105,Tolerated,"33,17","17,26"
"low bq, low freq, many artifacts, many samples",UPN2_006,4,106197545,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser1960Thr/c.5878T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5911,61,6007,"0,0101548194",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,105,Tolerated,"33,77","21,03"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106197545,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser1960Thr/c.5878T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6006,80,6114,"0,0130847236",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,105,Tolerated,"33,05","19,29"
"low bq, low freq, many artifacts, many samples",UPN2_050,4,106197545,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser1960Thr/c.5878T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7424,90,7554,"0,0119142176",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,105,Tolerated,"33,02","17,49"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106197545,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser1960Thr/c.5878T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),8360,106,8515,"0,0124486201",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,105,Tolerated,"33,1","20,12"
"low bq, low freq, many artifacts, many samples",UPN2_052,4,106197545,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser1960Thr/c.5878T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5986,73,6102,"0,0119632907",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,105,Tolerated,"32,94","15,64"
"low bq, low freq, many artifacts, many samples",UPN2_053,4,106197545,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser1960Thr/c.5878T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9790,123,9957,"0,0123531184",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,105,Tolerated,33,"17,41"
"low bq, low freq, many artifacts, many samples",UPN2_054,4,106197545,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser1960Thr/c.5878T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7558,85,7675,"0,0110749186",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,105,Tolerated,"32,94","19,19"
"low bq, low freq, many artifacts, many samples",UPN2_055,4,106197545,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser1960Thr/c.5878T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9939,124,10124,"0,0122481233",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,105,Tolerated,"33,02","18,6"
"low bq, low freq, many artifacts, many samples",UPN2_056,4,106197545,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser1960Thr/c.5878T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3620,40,3682,"0,0108636611",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,105,Tolerated,"33,11","17,65"
"low bq, low freq, many artifacts, many samples",UPN2_057,4,106197545,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser1960Thr/c.5878T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7893,86,8011,"0,010735239",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,105,Tolerated,"33,04","16,41"
"low bq, low freq, many artifacts",UPN2_058,4,106197545,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser1960Thr/c.5878T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9539,99,9684,"0,0102230483",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,105,Tolerated,"33,19","18,92"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_041,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1993,32,2027,"0,0157868772",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"26,3","14,81"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_089,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3550,55,3616,"0,015210177",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"26,05","14,65"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),10102,148,10292,"0,014380101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"26,23","14,84"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_043,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5748,96,5873,"0,0163459901",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"26,38","14,85"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_044,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2324,35,2370,"0,0147679325",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"26,06","14,2"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5522,102,5651,"0,0180499027",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"26,11","14,6"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),9835,144,10017,"0,0143755615",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"25,91","14,69"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),11609,186,11854,"0,015690906",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"26,07","14,74"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_048,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),8306,110,8439,"0,0130347198",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"26,19","14,53"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5994,98,6114,"0,0160287864",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"26,1","14,46"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),7422,91,7553,"0,0120481928",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"26,11","14,66"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),8324,141,8512,"0,0165648496",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"26,2","14,52"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5976,105,6101,"0,0172102934",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"25,76","14,87"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),9749,151,9955,"0,0151682572",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"25,79","14,66"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),7517,120,7673,"0,0156392545",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"25,84","14,18"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),9927,144,10121,"0,0142278431",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"25,81","14,88"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3608,60,3681,"0,0162999185",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"26,28","14,85"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_090,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3012,33,3060,"0,0107843137",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"26,5","14,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),7858,112,8010,"0,0139825218",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"26,16","14,31"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_058,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),9473,157,9683,"0,0162139833",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"26,45","14,54"
"low bq, bad alignment, many samples",UPN2_059,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4949,221,5184,"0,0426311728",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"23,73","14,99"
"low bq, bad alignment, many samples",UPN2_060,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3137,119,3270,"0,0363914373",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"23,79","15,29"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_091,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3145,53,3214,"0,0164903547",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"26,22","15,09"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_092,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1785,24,1818,"0,0132013201",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"26,22","15,21"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_093,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2659,44,2709,"0,0162421558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"26,26","14,32"
"low bq, bad alignment, many samples",UPN2_061,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3051,164,3227,"0,0508211962",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"23,49","14,35"
"low bq, bad alignment, many samples",UPN2_062,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2801,139,2953,"0,0470707755",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"23,28","14,55"
"low bq, bad alignment, many samples",UPN2_063,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2638,143,2794,"0,0511811024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"23,46","14,9"
"low bq, bad alignment, many samples",UPN2_064,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3473,153,3641,"0,0420214227",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"23,76","14,34"
"low bq, bad alignment, many samples",UPN2_065,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3899,190,4115,"0,0461725395",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"23,76","14,53"
"low bq, bad alignment, many samples",UPN2_066,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2968,111,3088,"0,0359455959",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"23,87","14,59"
"low bq, bad alignment, many samples",UPN2_067,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3884,176,4078,"0,043158411",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"24,08","14,7"
"low bq, bad alignment, many samples",UPN2_068,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3355,146,3510,"0,0415954416",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"23,29","14,76"
"low bq, bad alignment, many samples",UPN2_069,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4199,213,4423,"0,0481573593",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"23,54","14,57"
"low bq, bad alignment, many samples",UPN2_070,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2871,143,3024,"0,0472883598",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"23,44","14,86"
"low bq, bad alignment, many samples",UPN2_071,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2300,117,2421,"0,0483271375",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"23,56","14,76"
"low bq, bad alignment, many samples",UPN2_072,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3240,154,3407,"0,0452010566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"23,69","14,45"
"low bq, bad alignment, many samples",UPN2_073,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3565,153,3735,"0,0409638554",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"23,73","14,78"
"low bq, bad alignment, many samples",UPN2_074,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1930,96,2033,"0,0472208559",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"23,88","14,74"
"low bq, bad alignment, many samples",UPN2_075,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3966,205,4185,"0,0489844683",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"23,84","14,85"
"low bq, bad alignment, many samples",UPN2_076,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3984,220,4218,"0,0521574206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"23,42","14,52"
"low bq, bad alignment, many samples",UPN2_077,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3607,176,3795,"0,0463768116",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"23,73","14,74"
"low bq, bad alignment, many samples",UPN2_078,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3550,167,3731,"0,0447601179",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"23,24","14,83"
"low bq, bad alignment, many samples",UPN2_079,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2027,90,2132,"0,0422138837",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"23,59","14,7"
"low bq, bad alignment, many samples",UPN2_080,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3473,169,3657,"0,0462127427",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"23,52","14,41"
"low bq, bad alignment, many samples",UPN2_081,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5111,235,5356,"0,0438760269",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"23,9","14,53"
"low bq, bad alignment, many samples",UPN2_082,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3101,151,3269,"0,0461914959",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"23,83","14,95"
"low bq, bad alignment, many samples",UPN2_083,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4524,219,4759,"0,046018071",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"23,35","14,47"
"low bq, bad alignment, many samples",UPN2_084,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4274,196,4495,"0,0436040044",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"23,45","15,02"
"low bq, bad alignment, many samples",UPN2_085,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2655,147,2814,"0,052238806",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"23,72","14,42"
"low bq, bad alignment, many samples",UPN2_086,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1795,77,1876,"0,0410447761",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"23,65","14,66"
"low bq, bad alignment, many samples",UPN2_087,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4017,198,4230,"0,0468085106",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"23,6","14,78"
"low bq, bad alignment, many samples",UPN2_088,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4072,178,4270,"0,0416861827",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"23,86","14,44"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_094,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3449,57,3517,"0,0162069946",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"26,11","14,44"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_095,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3925,59,4000,"0,01475",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"25,96","14,24"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_096,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3393,58,3463,"0,016748484",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"26,13","14,67"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_097,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4195,48,4252,"0,0112888053",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"26,5","14,15"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_098,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4197,68,4281,"0,0158841392",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"26,13","14,1"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_099,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2243,29,2274,"0,0127528584",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"25,88",15
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_100,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3572,52,3630,"0,0143250689",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"26,72",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_101,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3961,52,4024,"0,0129224652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"25,76",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_102,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4171,75,4262,"0,0175973721",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"25,76","14,33"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_103,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4538,70,4617,"0,0151613602",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"25,91","14,4"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_104,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4395,62,4471,"0,0138671438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"25,71","14,35"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_105,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3865,69,3943,"0,017499366",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"26,17","14,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_106,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5394,67,5484,"0,0122173596",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"26,37","14,51"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_107,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6581,100,6706,"0,0149120191",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"26,38","14,35"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_108,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6360,83,6459,"0,0128502864",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"26,7","14,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_109,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6080,94,6195,"0,015173527",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"26,01","14,87"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_110,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4871,74,4967,"0,014898329",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"26,31","14,47"
"low bq, bad alignment, low freq, many artifacts",UPN2_111,4,106197549,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1961Ala/c.5882A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5860,113,5993,"0,0188553312",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,105,Tolerated,"25,93","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_060,4,106197551,C,A,missense_variant(MODERATE|MISSENSE|Ccc/Acc|p.Pro1962Thr/c.5884C>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3226,33,3268,"0,0100979192",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,35",Deleterious,2,Damaging,"31,45","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_066,4,106197551,C,A,missense_variant(MODERATE|MISSENSE|Ccc/Acc|p.Pro1962Thr/c.5884C>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3039,33,3088,"0,0106865285",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,35",Deleterious,2,Damaging,"31,23","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_074,4,106197551,C,A,missense_variant(MODERATE|MISSENSE|Ccc/Acc|p.Pro1962Thr/c.5884C>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1995,29,2032,"0,0142716535",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,35",Deleterious,2,Damaging,"31,16","14,45"
"low bq, low freq, many artifacts",UPN2_076,4,106197551,C,A,missense_variant(MODERATE|MISSENSE|Ccc/Acc|p.Pro1962Thr/c.5884C>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4151,43,4218,"0,0101944049",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,35",Deleterious,2,Damaging,"31,26",14
"low bq, bad alignment, many samples",UPN2_059,4,106197554,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1963Pro/c.5887A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5024,129,5181,"0,0248986682",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,52",Neutral,112,Tolerated,"25,25","15,04"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_060,4,106197554,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1963Pro/c.5887A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3188,64,3267,"0,0195898378",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,52",Neutral,112,Tolerated,"25,45","14,7"
"low bq, bad alignment, many samples",UPN2_061,4,106197554,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1963Pro/c.5887A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3113,94,3227,"0,0291292222",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,52",Neutral,112,Tolerated,"24,93","15,03"
"low bq, bad alignment, many samples",UPN2_062,4,106197554,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1963Pro/c.5887A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2849,81,2947,"0,0274855786",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,52",Neutral,112,Tolerated,"24,88","14,88"
"low bq, bad alignment, many samples",UPN2_063,4,106197554,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1963Pro/c.5887A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2685,91,2791,"0,0326048011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,52",Neutral,112,Tolerated,"24,92","14,66"
"low bq, bad alignment, many samples",UPN2_064,4,106197554,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1963Pro/c.5887A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3528,85,3637,"0,0233709101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,52",Neutral,112,Tolerated,"25,29","15,11"
"low bq, bad alignment, many samples",UPN2_065,4,106197554,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1963Pro/c.5887A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3987,95,4110,"0,0231143552",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,52",Neutral,112,Tolerated,"25,46","14,89"
"low bq, bad alignment, many samples",UPN2_066,4,106197554,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1963Pro/c.5887A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2991,82,3088,"0,0265544041",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,52",Neutral,112,Tolerated,"25,45","14,22"
"low bq, bad alignment, many samples",UPN2_067,4,106197554,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1963Pro/c.5887A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3958,99,4074,"0,0243004418",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,52",Neutral,112,Tolerated,"25,44","14,97"
"low bq, bad alignment, many samples",UPN2_068,4,106197554,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1963Pro/c.5887A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3376,98,3505,"0,0279600571",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,52",Neutral,112,Tolerated,"25,2","14,78"
"low bq, bad alignment, many samples",UPN2_069,4,106197554,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1963Pro/c.5887A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4253,139,4423,"0,0314266335",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,52",Neutral,112,Tolerated,"25,1","14,29"
"low bq, bad alignment, many samples",UPN2_070,4,106197554,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1963Pro/c.5887A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2914,81,3021,"0,0268123138",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,52",Neutral,112,Tolerated,"25,19","14,69"
"low bq, bad alignment, many samples",UPN2_071,4,106197554,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1963Pro/c.5887A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2350,57,2418,"0,023573201",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,52",Neutral,112,Tolerated,"25,17","14,88"
"low bq, bad alignment, many samples",UPN2_072,4,106197554,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1963Pro/c.5887A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3285,97,3403,"0,0285042609",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,52",Neutral,112,Tolerated,"25,24","14,33"
"low bq, bad alignment, many samples",UPN2_073,4,106197554,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1963Pro/c.5887A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3620,88,3732,"0,0235798499",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,52",Neutral,112,Tolerated,"25,53","15,43"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,4,106197554,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1963Pro/c.5887A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1981,40,2032,"0,0196850394",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,52",Neutral,112,Tolerated,"25,17","14,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_075,4,106197554,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1963Pro/c.5887A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4073,84,4179,"0,0201005025",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,52",Neutral,112,Tolerated,"25,37","15,06"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,4,106197554,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1963Pro/c.5887A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4101,87,4216,"0,0206356736",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,52",Neutral,112,Tolerated,"24,58","14,39"
"low bq, bad alignment, many samples",UPN2_077,4,106197554,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1963Pro/c.5887A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3662,103,3790,"0,027176781",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,52",Neutral,112,Tolerated,"24,79","14,79"
"low bq, bad alignment, many samples",UPN2_078,4,106197554,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1963Pro/c.5887A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3605,104,3726,"0,0279119699",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,52",Neutral,112,Tolerated,"24,69","14,97"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_079,4,106197554,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1963Pro/c.5887A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2074,43,2130,"0,0201877934",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,52",Neutral,112,Tolerated,"25,26","15,77"
"low bq, bad alignment, many samples",UPN2_080,4,106197554,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1963Pro/c.5887A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3550,84,3656,"0,02297593",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,52",Neutral,112,Tolerated,"25,35","15,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_081,4,106197554,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1963Pro/c.5887A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5215,111,5350,"0,0207476636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,52",Neutral,112,Tolerated,"25,41","14,45"
"low bq, bad alignment, many samples",UPN2_082,4,106197554,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1963Pro/c.5887A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3161,83,3265,"0,0254211332",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,52",Neutral,112,Tolerated,"25,49","14,67"
"low bq, bad alignment, many samples",UPN2_083,4,106197554,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1963Pro/c.5887A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4596,125,4755,"0,0262881178",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,52",Neutral,112,Tolerated,"24,71","15,02"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,4,106197554,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1963Pro/c.5887A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4362,96,4493,"0,0213665702",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,52",Neutral,112,Tolerated,"24,96","14,78"
"low bq, bad alignment, many samples",UPN2_085,4,106197554,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1963Pro/c.5887A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2712,79,2812,"0,0280938834",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,52",Neutral,112,Tolerated,"25,14","14,32"
"low bq, bad alignment, many samples",UPN2_086,4,106197554,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1963Pro/c.5887A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),1812,54,1874,"0,0288153682",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,52",Neutral,112,Tolerated,"25,33","14,67"
"low bq, bad alignment, many samples",UPN2_087,4,106197554,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1963Pro/c.5887A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4064,128,4224,"0,0303030303",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,52",Neutral,112,Tolerated,"25,06","14,66"
"low bq, bad alignment",UPN2_088,4,106197554,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1963Pro/c.5887A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4153,100,4269,"0,0234246896",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,52",Neutral,112,Tolerated,"25,34","14,27"
"low freq, many artifacts",UPN2_041,4,106197554,A,G,missense_variant(MODERATE|MISSENSE|Act/Gct|p.Thr1963Ala/c.5887A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),1988,22,2026,"0,0108588351",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,43,Damaging,"28,11",29
"low bq, low freq, many artifacts, many samples",UPN2_002,4,106197557,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1964Asn/c.5890T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4302,45,4357,"0,0103282075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,17",Deleterious,4,Damaging,"32,94","20,33"
"low bq, low freq, many artifacts, many samples",UPN2_041,4,106197557,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1964Asn/c.5890T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1986,27,2021,"0,0133597229",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,17",Deleterious,4,Damaging,"32,52","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106197557,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1964Asn/c.5890T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),10088,123,10262,"0,0119859676",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,17",Deleterious,4,Damaging,"32,21","16,51"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106197557,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1964Asn/c.5890T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5763,71,5860,"0,012116041",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,17",Deleterious,4,Damaging,"32,15","16,83"
"low bq, many samples",UPN2_044,4,106197557,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1964Asn/c.5890T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2264,77,2364,"0,032571912",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,17",Deleterious,4,Damaging,"32,27","25,22"
"low bq, low freq, many artifacts, many samples",UPN2_045,4,106197557,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1964Asn/c.5890T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5533,70,5640,"0,0124113475",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,17",Deleterious,4,Damaging,"32,36","16,71"
"low bq, low freq, many artifacts, many samples",UPN2_046,4,106197557,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1964Asn/c.5890T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9846,107,10001,"0,0106989301",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,17",Deleterious,4,Damaging,"32,14","16,43"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106197557,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1964Asn/c.5890T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),11658,138,11829,"0,011666244",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,17",Deleterious,4,Damaging,"32,3","15,59"
"low bq, low freq, many artifacts, many samples",UPN2_048,4,106197557,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1964Asn/c.5890T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),8273,99,8418,"0,0117605132",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,17",Deleterious,4,Damaging,"32,26","15,92"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106197557,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1964Asn/c.5890T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6001,75,6106,"0,0122830003",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,17",Deleterious,4,Damaging,"31,94","15,39"
"low bq, low freq, many artifacts, many samples",UPN2_050,4,106197557,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1964Asn/c.5890T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7406,90,7530,"0,0119521912",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,17",Deleterious,4,Damaging,"32,23","16,06"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106197557,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1964Asn/c.5890T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),8358,110,8496,"0,0129472693",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,17",Deleterious,4,Damaging,"32,26","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_052,4,106197557,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1964Asn/c.5890T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5978,77,6085,"0,0126540674",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,17",Deleterious,4,Damaging,"32,06","16,14"
"low bq, low freq, many artifacts, many samples",UPN2_053,4,106197557,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1964Asn/c.5890T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9783,115,9936,"0,0115740741",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,17",Deleterious,4,Damaging,"32,01","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_054,4,106197557,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1964Asn/c.5890T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7540,79,7655,"0,0103200523",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,17",Deleterious,4,Damaging,"32,19","16,81"
"low bq, low freq, many artifacts, many samples",UPN2_055,4,106197557,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1964Asn/c.5890T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9939,129,10103,"0,0127684846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,17",Deleterious,4,Damaging,"32,11","16,19"
"low bq, low freq, many artifacts, many samples",UPN2_057,4,106197557,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1964Asn/c.5890T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7849,102,7989,"0,0127675554",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,17",Deleterious,4,Damaging,"32,2","15,06"
"low bq, low freq, many artifacts",UPN2_058,4,106197557,T,A,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr1964Asn/c.5890T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9497,104,9660,"0,0107660455",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,17",Deleterious,4,Damaging,"32,32","16,03"
"low bq, low freq, many artifacts",UPN2_079,4,106197558,A,C,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr1964Ser/c.5891A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),2093,24,2127,"0,0112834979",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,91E-005",NO,NO,"-3,29",Deleterious,"0,01",Damaging,"27,96",14
"low bq, low freq, many artifacts, many samples",UPN2_001,4,106197561,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu1965Gln/c.5894T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3813,44,3876,"0,0113519092",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,4,Damaging,"32,79","17,89"
"low bq, low freq, many artifacts, many samples",UPN2_017,4,106197561,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu1965Gln/c.5894T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2708,30,2751,"0,0109051254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,4,Damaging,"32,83","18,27"
"low bq, low freq, many artifacts, many samples",UPN2_041,4,106197561,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu1965Gln/c.5894T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1961,33,2020,"0,0163366337",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,4,Damaging,"31,7","21,88"
"low bq, low freq, many artifacts, many samples",UPN2_026,4,106197561,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu1965Gln/c.5894T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),8274,91,8397,"0,0108372038",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,4,Damaging,"32,74","17,55"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106197561,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu1965Gln/c.5894T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),10079,130,10256,"0,012675507",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,4,Damaging,"31,8","17,88"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106197561,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu1965Gln/c.5894T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5729,86,5858,"0,0146807784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,4,Damaging,"31,88","18,12"
"low bq, low freq, many artifacts, many samples",UPN2_044,4,106197561,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu1965Gln/c.5894T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2317,31,2363,"0,0131189166",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,4,Damaging,"31,89","17,26"
"low bq, low freq, many artifacts, many samples",UPN2_045,4,106197561,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu1965Gln/c.5894T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5537,71,5639,"0,0125908849",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,4,Damaging,"31,76","18,2"
"low bq, low freq, many artifacts, many samples",UPN2_032,4,106197561,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu1965Gln/c.5894T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2552,26,2591,"0,0100347356",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,4,Damaging,"32,8","18,23"
"low bq, low freq, many artifacts, many samples",UPN2_046,4,106197561,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu1965Gln/c.5894T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9808,121,9995,"0,012106053",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,4,Damaging,"31,7","16,66"
"low bq, low freq, many artifacts, many samples",UPN2_033,4,106197561,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu1965Gln/c.5894T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6303,68,6390,"0,0106416275",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,4,Damaging,"32,78","17,24"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106197561,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu1965Gln/c.5894T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),11595,143,11821,"0,0120971153",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,4,Damaging,"31,9","17,18"
"low bq, low freq, many artifacts, many samples",UPN2_048,4,106197561,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu1965Gln/c.5894T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),8242,134,8412,"0,0159296243",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,4,Damaging,"31,83","20,58"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106197561,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu1965Gln/c.5894T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5971,95,6104,"0,0155635649",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,4,Damaging,"31,51","18,56"
"low bq, low freq, many artifacts, many samples",UPN2_050,4,106197561,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu1965Gln/c.5894T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7370,108,7527,"0,014348346",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,4,Damaging,"31,73","16,8"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106197561,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu1965Gln/c.5894T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),8312,120,8493,"0,0141292829",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,4,Damaging,"31,83","19,14"
"low bq, low freq, many artifacts, many samples",UPN2_052,4,106197561,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu1965Gln/c.5894T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5946,88,6083,"0,0144665461",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,4,Damaging,"31,55","17,25"
"low bq, low freq, many artifacts, many samples",UPN2_053,4,106197561,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu1965Gln/c.5894T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9745,145,9933,"0,0145978053",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,4,Damaging,"31,53","17,36"
"low bq, low freq, many artifacts, many samples",UPN2_054,4,106197561,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu1965Gln/c.5894T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7514,102,7653,"0,0133281066",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,4,Damaging,"31,65","17,34"
"low bq, low freq, many artifacts, many samples",UPN2_007,4,106197561,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu1965Gln/c.5894T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),10596,109,10762,"0,010128229",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,4,Damaging,"32,76","17,15"
"low bq, low freq, many artifacts, many samples",UPN2_010,4,106197561,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu1965Gln/c.5894T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9411,97,9562,"0,0101443213",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,4,Damaging,"32,75","17,76"
"low bq, low freq, many artifacts, many samples",UPN2_055,4,106197561,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu1965Gln/c.5894T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9908,120,10101,"0,0118800119",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,4,Damaging,"31,62","16,94"
"low bq, low freq, many artifacts, many samples",UPN2_056,4,106197561,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu1965Gln/c.5894T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3584,40,3668,"0,0109051254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,4,Damaging,"31,69","19,3"
"low bq, low freq, many artifacts, many samples",UPN2_057,4,106197561,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu1965Gln/c.5894T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7815,112,7985,"0,0140262993",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,4,Damaging,"31,73","18,96"
"low bq, low freq, many artifacts, many samples",UPN2_058,4,106197561,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu1965Gln/c.5894T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9462,132,9652,"0,0136759221",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,4,Damaging,"31,93","18,37"
"low bq, low freq, many artifacts, many samples",UPN2_064,4,106197561,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu1965Gln/c.5894T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3563,37,3634,"0,0101816181",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,4,Damaging,"31,08","18,05"
"low bq, low freq, many artifacts, many samples",UPN2_065,4,106197561,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu1965Gln/c.5894T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4036,44,4104,"0,0107212476",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,4,Damaging,"31,16","16,91"
"low bq, low freq, many artifacts, many samples",UPN2_066,4,106197561,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu1965Gln/c.5894T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3033,34,3084,"0,0110246433",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,4,Damaging,"30,9","18,38"
"low bq, low freq, many artifacts, many samples",UPN2_069,4,106197561,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu1965Gln/c.5894T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4332,51,4419,"0,0115410726",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,4,Damaging,"30,85","17,02"
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106197561,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu1965Gln/c.5894T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3332,39,3398,"0,0114773396",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,4,Damaging,"31,2","16,9"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106197561,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu1965Gln/c.5894T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3669,38,3722,"0,0102095648",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,4,Damaging,"31,39","17,32"
"low bq, low freq, many artifacts, many samples",UPN2_074,4,106197561,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu1965Gln/c.5894T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1991,21,2030,"0,0103448276",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,4,Damaging,"31,06","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_075,4,106197561,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu1965Gln/c.5894T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4088,49,4169,"0,0117534181",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,4,Damaging,"31,31","17,84"
"low bq, low freq, many artifacts, many samples",UPN2_076,4,106197561,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu1965Gln/c.5894T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4120,52,4209,"0,0123544785",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,4,Damaging,"30,91","19,6"
"low bq, low freq, many artifacts, many samples",UPN2_082,4,106197561,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu1965Gln/c.5894T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3193,35,3256,"0,0107493857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,4,Damaging,"31,09","17,34"
"low bq, low freq, many artifacts, many samples",UPN2_083,4,106197561,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu1965Gln/c.5894T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4666,50,4748,"0,0105307498",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,4,Damaging,"30,9","18,62"
"low bq, low freq, many artifacts, many samples",UPN2_087,4,106197561,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu1965Gln/c.5894T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4138,43,4213,"0,0102065037",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,4,Damaging,"30,86","18,23"
"low bq, low freq, many artifacts",UPN2_088,4,106197561,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu1965Gln/c.5894T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4187,44,4262,"0,0103237916",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,4,Damaging,"31,03","15,91"
"low bq, low freq, many artifacts, many samples",UPN2_002,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4427,46,4509,"0,0102018186",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"31,28","18,57"
"low bq, low freq, many artifacts, many samples",UPN2_041,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2010,38,2069,"0,0183663606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"29,64","15,87"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),10365,153,10609,"0,0144217174",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"29,52","15,46"
"low bq, low freq, many artifacts, many samples",UPN2_043,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5930,78,6066,"0,0128585559",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"29,42","15,41"
"low bq, low freq, many artifacts, many samples",UPN2_044,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2383,29,2431,"0,0119292472",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"29,37","15,31"
"low bq, low freq, many artifacts, many samples",UPN2_045,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5710,76,5838,"0,0130181569",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"29,19","15,93"
"low bq, low freq, many artifacts, many samples",UPN2_046,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),10114,142,10338,"0,0137357322",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"29,41","15,92"
"low bq, low freq, many artifacts, many samples",UPN2_047,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),12026,162,12294,"0,0131771596",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"29,43","15,78"
"low bq, low freq, many artifacts, many samples",UPN2_048,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),8496,131,8712,"0,0150367309",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"29,35","17,08"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6141,96,6298,"0,0152429343",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"29,28","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_050,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7605,120,7792,"0,0154004107",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"29,27","15,52"
"low bq, low freq, many artifacts, many samples",UPN2_051,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),8557,129,8784,"0,0146857923",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"29,43","16,16"
"low bq, low freq, many artifacts, many samples",UPN2_052,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6180,91,6327,"0,0143828039",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"29,2","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_053,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),10012,158,10279,"0,0153711451",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"29,23","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_054,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),7760,117,7952,"0,0147132797",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"29,24","15,37"
"low bq, low freq, many artifacts, many samples",UPN2_007,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),10943,121,11128,"0,0108734723",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"31,71","15,41"
"low bq, low freq, many artifacts, many samples",UPN2_055,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),10242,142,10484,"0,0135444487",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"29,3","15,98"
"low bq, low freq, many artifacts, many samples",UPN2_056,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3693,48,3775,"0,0127152318",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"29,21","16,67"
"low bq, low freq, many artifacts, many samples",UPN2_057,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),8109,122,8321,"0,0146616993",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"29,38","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_058,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),9736,150,9989,"0,0150165182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"29,54","16,98"
"low bq, low freq, many artifacts, many samples",UPN2_060,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3300,34,3378,"0,0100651273",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"28,12","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_061,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3248,34,3335,"0,0101949025",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"27,71","15,68"
"low bq, low freq, many artifacts, many samples",UPN2_062,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2964,34,3047,"0,0111585166",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"27,72","15,56"
"low bq, low freq, many artifacts, many samples",UPN2_063,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2807,29,2868,"0,010111576",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"27,61","15,52"
"low bq, low freq, many artifacts, many samples",UPN2_064,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3626,51,3736,"0,0136509636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"27,81","15,65"
"low bq, low freq, many artifacts, many samples",UPN2_065,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4125,55,4230,"0,0130023641",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"27,88","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_066,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3121,34,3199,"0,0106283214",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"28,06","15,56"
"low bq, low freq, many artifacts, many samples",UPN2_067,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4083,50,4165,"0,0120048019",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"27,87",14
"low bq, low freq, many artifacts, many samples",UPN2_069,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4442,48,4569,"0,0105055811",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"27,43","15,83"
"low bq, low freq, many artifacts, many samples",UPN2_070,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3018,36,3102,"0,0116054159",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"27,73","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_071,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2432,26,2492,"0,0104333868",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"27,85","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3730,42,3831,"0,010963195",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"27,92","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_074,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2061,26,2114,"0,0122989593",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"27,65",15
"low bq, low freq, many artifacts, many samples",UPN2_076,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4267,52,4369,"0,0119020371",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"27,68","15,96"
"low bq, low freq, many artifacts, many samples",UPN2_077,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3797,50,3908,"0,0127942682",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"27,67","17,62"
"low bq, low freq, many artifacts, many samples",UPN2_079,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2129,25,2194,"0,0113947129",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"27,77","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_080,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3696,43,3788,"0,0113516367",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"27,84","17,42"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5390,75,5531,"0,0135599349",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"28,04","15,95"
"low bq, low freq, many artifacts, many samples",UPN2_082,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),3320,37,3415,"0,0108345534",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"28,07","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_083,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4791,51,4913,"0,0103806228",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"27,57","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_084,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4488,57,4611,"0,0123617437",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"27,71","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_085,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2808,40,2892,"0,0138312586",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"27,74","15,75"
"low bq, low freq, many artifacts, many samples",UPN2_086,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),1856,26,1919,"0,0135487233",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"27,82","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_087,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4268,45,4382,"0,0102692834",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"27,87","16,42"
"low bq, low freq, many artifacts",UPN2_088,4,106197566,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1967Ile/c.5899T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4294,47,4415,"0,0106455266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,6,Damaging,"27,91","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_059,4,106197566,T,G,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe1967Val/c.5899T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),5182,55,5312,"0,0103539157",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,66",Deleterious,7,Damaging,"28,06","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_061,4,106197566,T,G,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe1967Val/c.5899T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),3248,41,3335,"0,0122938531",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,66",Deleterious,7,Damaging,"27,71","15,61"
"low bq, low freq, many artifacts, many samples",UPN2_062,4,106197566,T,G,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe1967Val/c.5899T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),2964,41,3047,"0,0134558582",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,66",Deleterious,7,Damaging,"27,72","15,39"
"low bq, low freq, many artifacts, many samples",UPN2_064,4,106197566,T,G,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe1967Val/c.5899T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),3626,42,3736,"0,01124197",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,66",Deleterious,7,Damaging,"27,81","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_068,4,106197566,T,G,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe1967Val/c.5899T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),3505,48,3604,"0,013318535",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,66",Deleterious,7,Damaging,"27,6","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_069,4,106197566,T,G,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe1967Val/c.5899T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),4442,57,4569,"0,0124753775",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,66",Deleterious,7,Damaging,"27,43","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_070,4,106197566,T,G,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe1967Val/c.5899T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),3018,38,3102,"0,0122501612",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,66",Deleterious,7,Damaging,"27,73","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106197566,T,G,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe1967Val/c.5899T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),3730,42,3831,"0,010963195",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,66",Deleterious,7,Damaging,"27,92","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_075,4,106197566,T,G,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe1967Val/c.5899T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),4190,46,4297,"0,0107051431",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,66",Deleterious,7,Damaging,"27,89","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_079,4,106197566,T,G,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe1967Val/c.5899T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),2129,29,2194,"0,0132178669",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,66",Deleterious,7,Damaging,"27,77",14
"low bq, low freq, many artifacts, many samples",UPN2_082,4,106197566,T,G,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe1967Val/c.5899T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),3320,38,3415,"0,0111273792",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,66",Deleterious,7,Damaging,"28,07","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_083,4,106197566,T,G,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe1967Val/c.5899T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),4791,50,4913,"0,0101770812",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,66",Deleterious,7,Damaging,"27,57","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_085,4,106197566,T,G,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe1967Val/c.5899T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),2808,30,2892,"0,010373444",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,66",Deleterious,7,Damaging,"27,74","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_086,4,106197566,T,G,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe1967Val/c.5899T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),1856,24,1919,"0,0125065138",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,66",Deleterious,7,Damaging,"27,82","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_087,4,106197566,T,G,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe1967Val/c.5899T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),4268,49,4382,"0,0111821086",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,66",Deleterious,7,Damaging,"27,87","14,27"
"low bq, low freq, many artifacts",UPN2_088,4,106197566,T,G,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe1967Val/c.5899T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),4294,48,4415,"0,0108720272",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,66",Deleterious,7,Damaging,"27,91","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_061,4,106197569,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1968Leu/c.5902A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6394,70,6495,"0,0107775212",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,35,Damaging,"29,25","14,19"
"low bq, low freq, many artifacts, many samples",UPN2_063,4,106197569,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1968Leu/c.5902A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5541,64,5633,"0,011361619",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,35,Damaging,"29,4","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_070,4,106197569,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1968Leu/c.5902A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5980,68,6077,"0,0111897318",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,35,Damaging,"29,11","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_076,4,106197569,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1968Leu/c.5902A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),8343,88,8487,"0,0103687993",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,35,Damaging,"29,15","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_079,4,106197569,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1968Leu/c.5902A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4229,44,4289,"0,0102588016",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,35,Damaging,"29,29","17,5"
"low bq, low freq, many artifacts, many samples",UPN2_083,4,106197569,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1968Leu/c.5902A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),9449,99,9591,"0,010322177",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,35,Damaging,"29,27","14,52"
"low bq, low freq, many artifacts",UPN2_088,4,106197569,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1968Leu/c.5902A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),8469,98,8601,"0,011394024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,35,Damaging,"29,48","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_042,4,106197579,T,A,missense_variant(MODERATE|MISSENSE|cTt/cAt|p.Leu1971His/c.5912T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),20397,216,20719,"0,0104252136",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,4,Damaging,"31,22","17,86"
"low bq, low freq, many artifacts, many samples",UPN2_044,4,106197579,T,A,missense_variant(MODERATE|MISSENSE|cTt/cAt|p.Leu1971His/c.5912T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),4689,49,4769,"0,0102746907",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,4,Damaging,"31,24","19,08"
"low bq, low freq, many artifacts, many samples",UPN2_046,4,106197579,T,A,missense_variant(MODERATE|MISSENSE|cTt/cAt|p.Leu1971His/c.5912T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),19797,231,20179,"0,0114475445",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,4,Damaging,"31,09","20,43"
"low bq, low freq, many artifacts, many samples",UPN2_048,4,106197579,T,A,missense_variant(MODERATE|MISSENSE|cTt/cAt|p.Leu1971His/c.5912T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),16685,195,16996,"0,0114732878",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,4,Damaging,"31,2","18,18"
"low bq, low freq, many artifacts, many samples",UPN2_049,4,106197579,T,A,missense_variant(MODERATE|MISSENSE|cTt/cAt|p.Leu1971His/c.5912T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),12073,183,12315,"0,0148599269",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,4,Damaging,"31,01","21,68"
"low bq, low freq, many artifacts, many samples",UPN2_050,4,106197579,T,A,missense_variant(MODERATE|MISSENSE|cTt/cAt|p.Leu1971His/c.5912T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),14960,159,15226,"0,0104426639",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,4,Damaging,"31,18","18,91"
"low bq, low freq, many artifacts, many samples",UPN2_052,4,106197579,T,A,missense_variant(MODERATE|MISSENSE|cTt/cAt|p.Leu1971His/c.5912T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),12066,132,12285,"0,0107448107",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,4,Damaging,"31,04","17,98"
"low bq, low freq, many artifacts, many samples",UPN2_054,4,106197579,T,A,missense_variant(MODERATE|MISSENSE|cTt/cAt|p.Leu1971His/c.5912T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),15166,156,15452,"0,0100957805",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,4,Damaging,"31,24","17,02"
"low bq, low freq, many artifacts, many samples",UPN2_063,4,106197579,T,A,missense_variant(MODERATE|MISSENSE|cTt/cAt|p.Leu1971His/c.5912T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5528,58,5632,"0,0102982955",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,4,Damaging,"29,63","18,5"
"low bq, low freq, many artifacts, many samples",UPN2_075,4,106197579,T,A,missense_variant(MODERATE|MISSENSE|cTt/cAt|p.Leu1971His/c.5912T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),8275,88,8405,"0,0104699584",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,4,Damaging,"29,75","18,81"
"low bq, low freq, many artifacts",UPN2_085,4,106197579,T,A,missense_variant(MODERATE|MISSENSE|cTt/cAt|p.Leu1971His/c.5912T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),5573,57,5671,"0,0100511374",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,4,Damaging,"29,45","16,11"
"low bq, low freq, many artifacts, many samples",UPN2_059,4,106197590,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1975Pro/c.5923A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),10212,163,10411,"0,0156565171",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,43",Neutral,1,Damaging,"29,22","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_060,4,106197590,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1975Pro/c.5923A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6414,109,6557,"0,0166234558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,43",Neutral,1,Damaging,"29,12","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_061,4,106197590,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1975Pro/c.5923A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6321,110,6468,"0,0170068027",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,43",Neutral,1,Damaging,"28,93","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_062,4,106197590,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1975Pro/c.5923A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5778,101,5913,"0,0170810079",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,43",Neutral,1,Damaging,"29,24","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_063,4,106197590,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1975Pro/c.5923A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5486,84,5598,"0,0150053591",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,43",Neutral,1,Damaging,"29,18","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_064,4,106197590,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1975Pro/c.5923A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),7135,133,7309,"0,0181967437",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,43",Neutral,1,Damaging,"29,17","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_065,4,106197590,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1975Pro/c.5923A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),8079,136,8251,"0,0164828506",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,43",Neutral,1,Damaging,"29,4","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_066,4,106197590,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1975Pro/c.5923A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6104,87,6222,"0,0139826422",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,43",Neutral,1,Damaging,"29,15","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_067,4,106197590,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1975Pro/c.5923A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),8015,105,8182,"0,0128330482",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,43",Neutral,1,Damaging,"29,36","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_068,4,106197590,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1975Pro/c.5923A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6875,111,7035,"0,0157782516",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,43",Neutral,1,Damaging,"29,1","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_069,4,106197590,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1975Pro/c.5923A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),8710,124,8882,"0,0139608196",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,43",Neutral,1,Damaging,"28,8","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_070,4,106197590,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1975Pro/c.5923A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5956,78,6061,"0,0128691635",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,43",Neutral,1,Damaging,"28,82","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_071,4,106197590,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1975Pro/c.5923A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4758,83,4871,"0,0170396223",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,43",Neutral,1,Damaging,"28,99","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106197590,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1975Pro/c.5923A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6742,109,6868,"0,0158707047",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,43",Neutral,1,Damaging,"29,15","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106197590,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1975Pro/c.5923A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),7311,129,7487,"0,0172298651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,43",Neutral,1,Damaging,"29,23","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_074,4,106197590,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1975Pro/c.5923A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3994,70,4082,"0,0171484566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,43",Neutral,1,Damaging,"29,17","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_075,4,106197590,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1975Pro/c.5923A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),8201,115,8375,"0,0137313433",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,43",Neutral,1,Damaging,"29,3","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_076,4,106197590,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1975Pro/c.5923A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),8258,150,8452,"0,0177472788",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,43",Neutral,1,Damaging,"28,92","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_077,4,106197590,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1975Pro/c.5923A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),7441,114,7602,"0,0149960537",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,43",Neutral,1,Damaging,"28,91","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_078,4,106197590,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1975Pro/c.5923A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),7297,122,7459,"0,0163560799",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,43",Neutral,1,Damaging,"28,9","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_079,4,106197590,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1975Pro/c.5923A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4171,77,4273,"0,0180201264",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,43",Neutral,1,Damaging,"29,04","15,73"
"low bq, low freq, many artifacts, many samples",UPN2_080,4,106197590,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1975Pro/c.5923A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),7162,121,7335,"0,0164962509",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,43",Neutral,1,Damaging,"29,18","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_081,4,106197590,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1975Pro/c.5923A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),10514,160,10748,"0,0148864905",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,43",Neutral,1,Damaging,"29,21","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_082,4,106197590,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1975Pro/c.5923A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6419,91,6537,"0,0139207588",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,43",Neutral,1,Damaging,"29,23","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_083,4,106197590,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1975Pro/c.5923A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),9376,144,9563,"0,0150580362",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,43",Neutral,1,Damaging,"28,76","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_084,4,106197590,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1975Pro/c.5923A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),8844,155,9037,"0,0171517096",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,43",Neutral,1,Damaging,"29,07","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_085,4,106197590,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1975Pro/c.5923A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5539,91,5657,"0,0160862648",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,43",Neutral,1,Damaging,"29,01","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_086,4,106197590,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1975Pro/c.5923A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3700,62,3775,"0,0164238411",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,43",Neutral,1,Damaging,"29,15","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_087,4,106197590,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1975Pro/c.5923A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),8322,139,8498,"0,0163567898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,43",Neutral,1,Damaging,"29,05","14,38"
"low bq, low freq, many artifacts",UPN2_088,4,106197590,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1975Pro/c.5923A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),8386,117,8568,"0,0136554622",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,43",Neutral,1,Damaging,"29,36","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_064,4,106197593,A,C,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met1976Leu/c.5926A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),7167,77,7275,"0,0105841924",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,1",Neutral,465,Tolerated,"29,82","15,91"
"low bq, low freq, many artifacts, many samples",UPN2_070,4,106197593,A,C,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met1976Leu/c.5926A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),5938,62,6031,"0,0102802189",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,1",Neutral,465,Tolerated,"29,61","17,16"
"low bq, low freq, many artifacts, many samples",UPN2_071,4,106197593,A,C,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met1976Leu/c.5926A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4772,51,4847,"0,0105219724",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,1",Neutral,465,Tolerated,"29,83","18,04"
"low bq, low freq, many artifacts, many samples",UPN2_072,4,106197593,A,C,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met1976Leu/c.5926A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),6711,72,6828,"0,0105448155",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,1",Neutral,465,Tolerated,"29,84","18,22"
"low bq, low freq, many artifacts, many samples",UPN2_073,4,106197593,A,C,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met1976Leu/c.5926A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),7343,76,7441,"0,010213681",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,1",Neutral,465,Tolerated,"30,03","15,7"
"low bq, low freq, many artifacts, many samples",UPN2_074,4,106197593,A,C,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met1976Leu/c.5926A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3989,54,4067,"0,0132776002",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,1",Neutral,465,Tolerated,"29,9","17,37"
"low bq, low freq, many artifacts, many samples",UPN2_076,4,106197593,A,C,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met1976Leu/c.5926A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),8309,86,8422,"0,0102113512",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,1",Neutral,465,Tolerated,"29,61","17,34"
"low bq, low freq, many artifacts, many samples",UPN2_077,4,106197593,A,C,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met1976Leu/c.5926A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),7464,82,7573,"0,0108279414",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,1",Neutral,465,Tolerated,"29,63","16,68"
"low bq, low freq, many artifacts, many samples",UPN2_079,4,106197593,A,C,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met1976Leu/c.5926A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),4184,48,4254,"0,0112834979",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,1",Neutral,465,Tolerated,"29,86","16,96"
"low bq, low freq, many artifacts, many samples",UPN2_080,4,106197593,A,C,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met1976Leu/c.5926A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),7195,75,7303,"0,0102697522",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,1",Neutral,465,Tolerated,"29,96","16,09"
"low bq, low freq, many artifacts",UPN2_086,4,106197593,A,C,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met1976Leu/c.5926A>C|2002|TET2|protein_coding|CODING|ENST00000380013|11|C),3678,45,3746,"0,0120128137",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,1",Neutral,465,Tolerated,"30,08","17,22"
"inspected, bad alignment, many artifacts",UPN2_041,4,106197615,C,A,missense_variant(MODERATE|MISSENSE|aCa/aAa|p.Thr1983Lys/c.5948C>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2035,34,2073,"0,0164013507",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,82",Deleterious,"0,002",Damaging,"34,28","31,62"
"inspected, bad alignment, many artifacts",UPN2_041,4,106197618,T,A,missense_variant(MODERATE|MISSENSE|gTa/gAa|p.Val1984Glu/c.5951T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2040,29,2073,"0,0139893874",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,0,Damaging,"34,24",33
"inspected, bad alignment, many artifacts",UPN2_044,4,106197629,C,T,missense_variant(MODERATE|MISSENSE|Cca/Tca|p.Pro1988Ser/c.5962C>T|2002|TET2|protein_coding|CODING|ENST00000380013|11|T),2364,39,2415,"0,0161490683",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,23",Deleterious,"0,099",Tolerated,"34,12","35,44"
"Not in 2nd Illumina, many artifacts, low freq",UPN2_006,4,106197645,G,A,missense_variant(MODERATE|MISSENSE|cGg/cAg|p.Arg1993Gln/c.5978G>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),6012,61,6097,"0,0100049205",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,57",Neutral,"0,229",Tolerated,"34,46","35,18"
"low bq, low freq, many artifacts",UPN2_084,4,106197648,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1994Gly/c.5981T>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),4531,47,4608,"0,0101996528",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,88",Deleterious,0,Damaging,"31,05","15,36"
"inspected, bad alignment, many artifacts",UPN2_044,4,106197650,A,G,missense_variant(MODERATE|MISSENSE|Aca/Gca|p.Thr1995Ala/c.5983A>G|2002|TET2|protein_coding|CODING|ENST00000380013|11|G),2374,35,2416,"0,014486755",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,57",Deleterious,"0,102",Tolerated,"34,81","32,94"
"inspected, bad alignment, many artifacts",UPN2_041,4,106197661,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr1998*/c.5994C>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2035,33,2074,"0,0159112825",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,99","35,21"
"inspected, bad alignment, many artifacts",UPN2_044,4,106197670,T,A,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr2001*/c.6003T>A|2002|TET2|protein_coding|CODING|ENST00000380013|11|A),2377,30,2417,"0,0124120811",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,12","34,4"
"low bq, low freq, many artifacts, many samples",UPN2_016,7,148504738,T,A,stop_lost(HIGH|MISSENSE|tgA/tgT|p.Ter752Cysext*?/c.2256A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5985,68,6071,"0,0112007906",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,04","20,22"
"low bq, low freq, many artifacts, many samples",UPN2_017,7,148504738,T,A,stop_lost(HIGH|MISSENSE|tgA/tgT|p.Ter752Cysext*?/c.2256A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3306,47,3362,"0,0139797739",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,1","17,02"
"low bq, low freq, many artifacts, many samples",UPN2_018,7,148504738,T,A,stop_lost(HIGH|MISSENSE|tgA/tgT|p.Ter752Cysext*?/c.2256A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6027,72,6118,"0,0117685518",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,68","18,29"
"low bq, low freq, many artifacts, many samples",UPN2_020,7,148504738,T,A,stop_lost(HIGH|MISSENSE|tgA/tgT|p.Ter752Cysext*?/c.2256A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3703,62,3771,"0,0164412623",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,82","18,55"
"low bq, low freq, many artifacts, many samples",UPN2_021,7,148504738,T,A,stop_lost(HIGH|MISSENSE|tgA/tgT|p.Ter752Cysext*?/c.2256A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6086,80,6179,"0,0129470788",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,63","17,15"
"low bq, low freq, many artifacts, many samples",UPN2_023,7,148504738,T,A,stop_lost(HIGH|MISSENSE|tgA/tgT|p.Ter752Cysext*?/c.2256A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9510,98,9640,"0,0101659751",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,99","18,86"
"low bq, low freq, many artifacts, many samples",UPN2_025,7,148504738,T,A,stop_lost(HIGH|MISSENSE|tgA/tgT|p.Ter752Cysext*?/c.2256A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10826,115,10978,"0,0104754964",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,97","16,76"
"low bq, low freq, many artifacts, many samples",UPN2_026,7,148504738,T,A,stop_lost(HIGH|MISSENSE|tgA/tgT|p.Ter752Cysext*?/c.2256A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8334,138,8495,"0,0162448499",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,86","16,78"
"low bq, low freq, many artifacts, many samples",UPN2_027,7,148504738,T,A,stop_lost(HIGH|MISSENSE|tgA/tgT|p.Ter752Cysext*?/c.2256A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11311,129,11471,"0,0112457502",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,1","18,17"
"low bq, low freq, many artifacts, many samples",UPN2_028,7,148504738,T,A,stop_lost(HIGH|MISSENSE|tgA/tgT|p.Ter752Cysext*?/c.2256A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9062,93,9184,"0,0101263066",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,5","16,9"
"low bq, low freq, many artifacts, many samples",UPN2_030,7,148504738,T,A,stop_lost(HIGH|MISSENSE|tgA/tgT|p.Ter752Cysext*?/c.2256A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8498,92,8624,"0,0106679035",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,17","17,74"
"low bq, low freq, many artifacts, many samples",UPN2_033,7,148504738,T,A,stop_lost(HIGH|MISSENSE|tgA/tgT|p.Ter752Cysext*?/c.2256A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5958,77,6053,"0,0127209648",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,37","17,66"
"low bq, low freq, many artifacts, many samples",UPN2_034,7,148504738,T,A,stop_lost(HIGH|MISSENSE|tgA/tgT|p.Ter752Cysext*?/c.2256A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1912,26,1948,"0,0133470226",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,52","17,92"
"low bq, low freq, many artifacts, many samples",UPN2_047,7,148504738,T,A,stop_lost(HIGH|MISSENSE|tgA/tgT|p.Ter752Cysext*?/c.2256A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10088,110,10228,"0,0107547908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,46","21,59"
"low bq, low freq, many artifacts, many samples",UPN2_048,7,148504738,T,A,stop_lost(HIGH|MISSENSE|tgA/tgT|p.Ter752Cysext*?/c.2256A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4135,42,4192,"0,010019084",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,55","21,57"
"low bq, low freq, many artifacts, many samples",UPN2_037,7,148504738,T,A,stop_lost(HIGH|MISSENSE|tgA/tgT|p.Ter752Cysext*?/c.2256A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9313,109,9457,"0,0115258539",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,14","16,82"
"low bq, low freq, many artifacts, many samples",UPN2_052,7,148504738,T,A,stop_lost(HIGH|MISSENSE|tgA/tgT|p.Ter752Cysext*?/c.2256A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5220,56,5287,"0,0105920182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,09","16,29"
"low bq, low freq, many artifacts, many samples",UPN2_038,7,148504738,T,A,stop_lost(HIGH|MISSENSE|tgA/tgT|p.Ter752Cysext*?/c.2256A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13473,163,13664,"0,0119291569",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,72","18,15"
"low bq, low freq, many artifacts, many samples",UPN2_053,7,148504738,T,A,stop_lost(HIGH|MISSENSE|tgA/tgT|p.Ter752Cysext*?/c.2256A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8706,117,8854,"0,0132143664",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,39","19,76"
"low bq, low freq, many artifacts, many samples",UPN2_007,7,148504738,T,A,stop_lost(HIGH|MISSENSE|tgA/tgT|p.Ter752Cysext*?/c.2256A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11812,125,11963,"0,0104488841",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,97","16,81"
"low bq, low freq, many artifacts, many samples",UPN2_008,7,148504738,T,A,stop_lost(HIGH|MISSENSE|tgA/tgT|p.Ter752Cysext*?/c.2256A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13229,144,13418,"0,0107318527",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,39","16,74"
"low bq, low freq, many artifacts, many samples",UPN2_009,7,148504738,T,A,stop_lost(HIGH|MISSENSE|tgA/tgT|p.Ter752Cysext*?/c.2256A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10968,125,11124,"0,0112369651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,43","15,96"
"low bq, low freq, many artifacts, many samples",UPN2_056,7,148504738,T,A,stop_lost(HIGH|MISSENSE|tgA/tgT|p.Ter752Cysext*?/c.2256A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2574,29,2610,"0,0111111111",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,4","17,03"
"low bq, low freq, many artifacts, many samples",UPN2_012,7,148504738,T,A,stop_lost(HIGH|MISSENSE|tgA/tgT|p.Ter752Cysext*?/c.2256A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3324,43,3379,"0,0127256585",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,04","15,02"
"low bq, low freq, many artifacts",UPN2_040,7,148504738,T,A,stop_lost(HIGH|MISSENSE|tgA/tgT|p.Ter752Cysext*?/c.2256A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8204,87,8320,"0,0104567308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,69","20,6"
"low bq, low freq, many artifacts, many samples",UPN2_019,7,148504746,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile750Phe/c.2248A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7781,85,7911,"0,0107445329",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,75",Neutral,647,Tolerated,"30,98","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_031,7,148504746,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile750Phe/c.2248A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5589,62,5685,"0,0109058927",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,75",Neutral,647,Tolerated,"31,55","16,08"
"low bq, low freq, many artifacts, many samples",UPN2_033,7,148504746,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile750Phe/c.2248A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5948,73,6049,"0,0120681104",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,75",Neutral,647,Tolerated,"30,42","16,07"
"low bq, low freq, many artifacts, many samples",UPN2_039,7,148504746,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile750Phe/c.2248A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),18316,189,18600,"0,0101612903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,75",Neutral,647,Tolerated,"30,97","15,51"
"low bq, low freq, many artifacts",UPN2_040,7,148504746,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile750Phe/c.2248A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8200,84,8318,"0,0100985814",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,75",Neutral,647,Tolerated,"31,34","15,63"
"low bq, low freq, many artifacts, many samples",UPN2_014,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8417,113,8554,"0,0132101941",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"28,6","18,25"
"low bq, low freq, many artifacts, many samples",UPN2_015,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11739,120,11904,"0,0100806452",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"29,3","17,1"
"low bq, low freq, many artifacts, many samples",UPN2_016,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5965,79,6068,"0,0130191167",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"28,07","17,19"
"low bq, low freq, many artifacts, many samples",UPN2_017,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3303,46,3358,"0,0136986301",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"28,33","16,37"
"low bq, low freq, many artifacts, many samples",UPN2_018,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6025,69,6110,"0,0112929624",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"27,69","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_019,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7781,98,7909,"0,012390947",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"28,7","17,69"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_020,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3678,74,3766,"0,0196494955",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"26,46","15,62"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_021,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6051,99,6172,"0,0160401815",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"26,27","16,52"
"low bq, low freq, many artifacts, many samples",UPN2_002,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4494,47,4556,"0,0103160667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"30,19","15,7"
"low bq, low freq, many artifacts, many samples",UPN2_022,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8737,126,8891,"0,0141716342",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"28,3","16,47"
"low bq, low freq, many artifacts, many samples",UPN2_023,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9498,100,9631,"0,0103831378",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"29,25","16,59"
"low bq, low freq, many artifacts, many samples",UPN2_024,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3084,34,3128,"0,0108695652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"28,54","15,5"
"low bq, low freq, many artifacts, many samples",UPN2_025,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10775,141,10962,"0,0128626163",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"27,98","15,94"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_026,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8337,124,8490,"0,0146054181",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"26,81","17,08"
"low bq, low freq, many artifacts, many samples",UPN2_027,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11278,141,11461,"0,0123025914",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"28,11","15,76"
"low bq, low freq, many artifacts, many samples",UPN2_042,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8595,91,8717,"0,0104393713",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"29,38","16,44"
"low bq, low freq, many artifacts, many samples",UPN2_028,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9009,126,9171,"0,0137389598",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"27,65","17,09"
"low bq, low freq, many artifacts, many samples",UPN2_029,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7908,85,8023,"0,0105945407",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"28,67","17,74"
"low bq, low freq, many artifacts, many samples",UPN2_030,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8487,105,8621,"0,0121795615",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"27,29","17,27"
"low bq, low freq, many artifacts, many samples",UPN2_031,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5605,58,5685,"0,0102022867",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"29,57","17,34"
"low bq, low freq, many artifacts, many samples",UPN2_045,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5023,66,5112,"0,0129107981",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"29,16","16,88"
"low bq, low freq, many artifacts, many samples",UPN2_046,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10859,112,11008,"0,0101744186",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"29,46","16,38"
"low bq, low freq, many artifacts, many samples",UPN2_033,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5939,81,6045,"0,0133995037",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"27,38","17,26"
"low bq, low freq, many artifacts, many samples",UPN2_034,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1911,29,1947,"0,0148947098",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"27,99","16,28"
"low bq, low freq, many artifacts, many samples",UPN2_047,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10070,111,10217,"0,0108642459",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"29,7","18,23"
"low bq, low freq, many artifacts, many samples",UPN2_048,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4123,50,4188,"0,011938873",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"29,41","15,68"
"low bq, low freq, many artifacts, many samples",UPN2_036,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13542,146,13723,"0,0106390731",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"29,08","16,7"
"low bq, low freq, many artifacts, many samples",UPN2_006,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5512,61,5602,"0,0108889682",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"30,21","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_050,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7708,101,7834,"0,0128925198",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"30,44","17,47"
"low bq, low freq, many artifacts, many samples",UPN2_037,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9270,131,9439,"0,0138785888",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"27,22","15,7"
"low bq, low freq, many artifacts, many samples",UPN2_052,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5168,82,5276,"0,0155420773",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"28,26","16,5"
"low bq, low freq, many artifacts, many samples",UPN2_038,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13418,194,13657,"0,0142051695",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"27,84","16,26"
"low bq, low freq, many artifacts, many samples",UPN2_039,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),18340,200,18598,"0,0107538445",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"28,88","17,27"
"low bq, low freq, many artifacts, many samples",UPN2_053,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8699,110,8844,"0,0124378109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"28,35","17,29"
"low bq, low freq, many artifacts, many samples",UPN2_007,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11789,132,11956,"0,0110404818",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"30,74","15,5"
"low bq, low freq, many artifacts, many samples",UPN2_008,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13209,164,13415,"0,0122251211",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"30,11","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_009,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10944,132,11119,"0,0118715712",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"29,95","15,49"
"low bq, low freq, many artifacts, many samples",UPN2_011,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10611,124,10774,"0,0115091888",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"30,77","16,39"
"low bq, low freq, many artifacts, many samples",UPN2_055,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9190,116,9357,"0,0123971358",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"29,59","17,09"
"low bq, low freq, many artifacts, many samples",UPN2_056,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2553,37,2608,"0,0141871166",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"28,51","15,97"
"low bq, low freq, many artifacts, many samples",UPN2_040,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8155,115,8314,"0,0138320904",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"28,94","16,17"
"low bq, low freq, many artifacts",UPN2_013,7,148504747,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu749Asp/c.2247A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2499,33,2541,"0,012987013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,56",Neutral,333,Tolerated,"30,18",16
"low bq, low freq, many artifacts, many samples",UPN2_016,7,148504748,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu749Val/c.2246A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5962,80,6065,"0,0131904369",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,15",Deleterious,1,Damaging,"27,78","15,93"
"low bq, low freq, many artifacts, many samples",UPN2_017,7,148504748,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu749Val/c.2246A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3298,48,3357,"0,0142984808",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,15",Deleterious,1,Damaging,"28,08","17,21"
"low bq, low freq, many artifacts, many samples",UPN2_018,7,148504748,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu749Val/c.2246A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6013,76,6104,"0,0124508519",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,15",Deleterious,1,Damaging,"27,66","16,49"
"low bq, low freq, many artifacts, many samples",UPN2_019,7,148504748,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu749Val/c.2246A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7793,91,7905,"0,0115117015",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,15",Deleterious,1,Damaging,"28,58","15,65"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_020,7,148504748,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu749Val/c.2246A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3677,78,3764,"0,0207226355",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,15",Deleterious,1,Damaging,"26,42","17,22"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_021,7,148504748,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu749Val/c.2246A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6035,115,6170,"0,0186385737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,15",Deleterious,1,Damaging,"25,98","15,65"
"low bq, low freq, many artifacts, many samples",UPN2_022,7,148504748,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu749Val/c.2246A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8750,107,8885,"0,0120427687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,15",Deleterious,1,Damaging,"28,11","17,21"
"low bq, low freq, many artifacts, many samples",UPN2_024,7,148504748,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu749Val/c.2246A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3080,34,3126,"0,0108765195",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,15",Deleterious,1,Damaging,"28,47","18,53"
"low bq, low freq, many artifacts, many samples",UPN2_025,7,148504748,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu749Val/c.2246A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10756,163,10952,"0,0148831264",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,15",Deleterious,1,Damaging,"27,7","15,93"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_026,7,148504748,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu749Val/c.2246A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8289,163,8486,"0,0192081075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,15",Deleterious,1,Damaging,"26,45","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_027,7,148504748,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu749Val/c.2246A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11249,165,11454,"0,0144054479",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,15",Deleterious,1,Damaging,"27,96","16,17"
"low bq, low freq, many artifacts, many samples",UPN2_042,7,148504748,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu749Val/c.2246A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8563,110,8714,"0,0126233647",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,15",Deleterious,1,Damaging,"29,69","17,79"
"low bq, low freq, many artifacts, many samples",UPN2_028,7,148504748,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu749Val/c.2246A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9014,117,9166,"0,0127645647",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,15",Deleterious,1,Damaging,"27,43","16,68"
"low bq, low freq, many artifacts, many samples",UPN2_045,7,148504748,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu749Val/c.2246A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5005,71,5108,"0,0138997651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,15",Deleterious,1,Damaging,"29,41","17,35"
"low bq, low freq, many artifacts, many samples",UPN2_046,7,148504748,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu749Val/c.2246A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10832,137,11005,"0,0124488869",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,15",Deleterious,1,Damaging,"29,5","16,56"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_033,7,148504748,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu749Val/c.2246A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5947,80,6043,"0,0132384577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,15",Deleterious,1,Damaging,"26,97","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_034,7,148504748,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu749Val/c.2246A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1908,28,1947,"0,0143810991",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,15",Deleterious,1,Damaging,"27,55","16,36"
"low bq, low freq, many artifacts, many samples",UPN2_047,7,148504748,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu749Val/c.2246A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10047,122,10213,"0,0119455596",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,15",Deleterious,1,Damaging,"29,69","18,01"
"low bq, low freq, many artifacts, many samples",UPN2_048,7,148504748,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu749Val/c.2246A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4114,49,4186,"0,0117056856",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,15",Deleterious,1,Damaging,"29,66","17,14"
"low bq, low freq, many artifacts, many samples",UPN2_036,7,148504748,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu749Val/c.2246A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13533,145,13718,"0,0105700539",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,15",Deleterious,1,Damaging,"28,89","16,75"
"low bq, low freq, many artifacts, many samples",UPN2_006,7,148504748,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu749Val/c.2246A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5531,57,5599,"0,0101803894",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,15",Deleterious,1,Damaging,"30,33","15,72"
"low bq, low freq, many artifacts, many samples",UPN2_037,7,148504748,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu749Val/c.2246A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9250,147,9435,"0,0155802862",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,15",Deleterious,1,Damaging,"27,08","16,61"
"low bq, low freq, many artifacts, many samples",UPN2_051,7,148504748,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu749Val/c.2246A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8127,93,8265,"0,0112522686",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,15",Deleterious,1,Damaging,"29,51","18,48"
"low bq, low freq, many artifacts, many samples",UPN2_052,7,148504748,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu749Val/c.2246A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5156,95,5274,"0,0180128934",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,15",Deleterious,1,Damaging,"28,24","17,35"
"low bq, low freq, many artifacts, many samples",UPN2_038,7,148504748,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu749Val/c.2246A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13402,217,13651,"0,0158962713",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,15",Deleterious,1,Damaging,"27,58","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_053,7,148504748,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu749Val/c.2246A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8673,138,8839,"0,0156126259",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,15",Deleterious,1,Damaging,"28,31","17,67"
"low bq, low freq, many artifacts, many samples",UPN2_008,7,148504748,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu749Val/c.2246A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13208,170,13410,"0,0126771066",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,15",Deleterious,1,Damaging,"30,15","16,86"
"low bq, low freq, many artifacts, many samples",UPN2_009,7,148504748,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu749Val/c.2246A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10957,132,11114,"0,011876912",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,15",Deleterious,1,Damaging,"30,16","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_055,7,148504748,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu749Val/c.2246A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9224,107,9354,"0,0114389566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,15",Deleterious,1,Damaging,"29,67","16,91"
"low bq, low freq, many artifacts, many samples",UPN2_056,7,148504748,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu749Val/c.2246A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2559,38,2605,"0,0145873321",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,15",Deleterious,1,Damaging,"28,75","16,79"
"low bq, low freq, many artifacts, many samples",UPN2_057,7,148504748,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu749Val/c.2246A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8463,87,8586,"0,0101327743",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,15",Deleterious,1,Damaging,"30,35","19,3"
"low bq, low freq, many artifacts, many samples",UPN2_012,7,148504748,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu749Val/c.2246A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3319,46,3376,"0,0136255924",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,15",Deleterious,1,Damaging,"29,73","17,26"
"low bq, low freq, many artifacts",UPN2_013,7,148504748,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu749Val/c.2246A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2505,30,2540,"0,0118110236",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,15",Deleterious,1,Damaging,"30,2","17,77"
"low bq, low freq, many artifacts, many samples",UPN2_052,7,148504749,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu749*/c.2245G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5206,59,5273,"0,0111890764",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,58","14,22"
"low bq, bad alignment, many samples",UPN2_095,7,148504749,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu749*/c.2245G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),769,22,791,"0,0278128951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"24,61",14
"low bq, bad alignment, many samples",UPN2_096,7,148504749,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu749*/c.2245G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),666,22,690,"0,031884058",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"23,52",14
"low bq, bad alignment, many samples",UPN2_098,7,148504749,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu749*/c.2245G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),887,22,910,"0,0241758242",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"24,27",14
"low bq, bad alignment, many samples",UPN2_102,7,148504749,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu749*/c.2245G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),803,21,828,"0,0253623188",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"23,51","15,05"
"low bq, bad alignment, many samples",UPN2_103,7,148504749,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu749*/c.2245G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),758,24,783,"0,030651341",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"23,59",14
"low bq, bad alignment, many samples",UPN2_106,7,148504749,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu749*/c.2245G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),553,20,573,"0,034904014",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"24,69",14
"low bq, bad alignment",UPN2_108,7,148504749,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu749*/c.2245G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),867,20,887,"0,0225479143",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"23,95",14
"low bq, bad alignment, many samples",UPN2_089,7,148504750,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met748Ile/c.2244G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),946,27,977,"0,0276356192",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,176,Tolerated,"23,48",14
"low bq, low freq, many artifacts, many samples",UPN2_042,7,148504750,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met748Ile/c.2244G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8588,95,8706,"0,0109120147",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,176,Tolerated,"29,16","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_048,7,148504750,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met748Ile/c.2244G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4132,45,4184,"0,0107552581",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,176,Tolerated,"29,48","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_051,7,148504750,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met748Ile/c.2244G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8157,94,8264,"0,011374637",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,176,Tolerated,"29,11",14
"low bq, low freq, many artifacts, many samples",UPN2_052,7,148504750,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met748Ile/c.2244G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5193,65,5272,"0,0123292868",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,176,Tolerated,"27,84",14
"low bq, low freq, many artifacts, many samples",UPN2_053,7,148504750,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met748Ile/c.2244G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8696,126,8834,"0,0142630745",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,176,Tolerated,"27,79","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_055,7,148504750,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met748Ile/c.2244G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9237,94,9349,"0,0100545513",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,176,Tolerated,"29,54",14
"low bq, low freq, many artifacts, many samples",UPN2_056,7,148504750,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met748Ile/c.2244G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2547,47,2603,"0,0180560891",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,176,Tolerated,"28,61",14
"low bq, low freq, many artifacts, many samples",UPN2_013,7,148504750,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met748Ile/c.2244G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2499,26,2540,"0,0102362205",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,176,Tolerated,"31,28","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_082,7,148504750,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met748Ile/c.2244G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1307,25,1333,"0,0187546887",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,176,Tolerated,28,14
"low bq, bad alignment, many samples",UPN2_095,7,148504750,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met748Ile/c.2244G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),762,29,791,"0,0366624526",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,176,Tolerated,"23,6",14
"low bq, bad alignment, many samples",UPN2_096,7,148504750,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met748Ile/c.2244G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),662,28,690,"0,0405797101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,176,Tolerated,"23,2",14
"low bq, bad alignment, many samples",UPN2_097,7,148504750,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met748Ile/c.2244G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),723,30,754,"0,0397877984",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,176,Tolerated,"23,47",14
"low bq, bad alignment, many samples",UPN2_098,7,148504750,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met748Ile/c.2244G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),886,22,909,"0,0242024202",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,176,Tolerated,"24,22","14,32"
"low bq, bad alignment, many samples",UPN2_100,7,148504750,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met748Ile/c.2244G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),918,26,945,"0,0275132275",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,176,Tolerated,"23,4","14,85"
"low bq, bad alignment, many samples",UPN2_102,7,148504750,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met748Ile/c.2244G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),807,20,828,"0,0241545894",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,176,Tolerated,"23,23",14
"low bq, bad alignment, many samples",UPN2_103,7,148504750,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met748Ile/c.2244G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),749,32,783,"0,0408684547",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,176,Tolerated,"22,75",14
"low bq, bad alignment, many samples",UPN2_105,7,148504750,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met748Ile/c.2244G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),797,39,839,"0,0464839094",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,176,Tolerated,"22,94","14,33"
"low bq, bad alignment, many samples",UPN2_107,7,148504750,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met748Ile/c.2244G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),713,28,741,"0,0377867746",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,176,Tolerated,"23,42","14,79"
"low bq, bad alignment, many samples",UPN2_108,7,148504750,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met748Ile/c.2244G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),849,34,886,"0,0383747178",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,176,Tolerated,"22,91",14
"low bq, bad alignment, many samples",UPN2_109,7,148504750,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met748Ile/c.2244G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),853,21,874,"0,02402746",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,176,Tolerated,"23,67",14
"low bq, bad alignment",UPN2_111,7,148504750,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met748Ile/c.2244G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),779,31,810,"0,0382716049",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,176,Tolerated,"23,29",14
"inspected, bad alignment, many artifacts",UPN2_041,7,148504750,C,T,missense_variant(MODERATE|MISSENSE|atG/atA|p.Met748Ile/c.2244G>A|751|EZH2|protein_coding|CODING|ENST00000320356|20|T),1219,21,1251,"0,0167865707",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,176",Tolerated,"29,43","32,19"
"low bq, low freq, many artifacts, many samples",UPN2_014,7,148504752,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met748Leu/c.2242A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8407,98,8551,"0,0114606479",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,279,Tolerated,"27,82","15,4"
"low bq, low freq, many artifacts, many samples",UPN2_016,7,148504752,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met748Leu/c.2242A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5977,67,6059,"0,0110579304",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,279,Tolerated,"27,61","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_017,7,148504752,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met748Leu/c.2242A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3295,43,3354,"0,0128205128",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,279,Tolerated,"27,64","14,93"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_020,7,148504752,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met748Leu/c.2242A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3698,49,3761,"0,0130284499",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,279,Tolerated,"26,73","14,82"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_021,7,148504752,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met748Leu/c.2242A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6056,81,6163,"0,0131429499",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,279,Tolerated,"26,56","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_022,7,148504752,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met748Leu/c.2242A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8765,92,8882,"0,0103580275",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,279,Tolerated,"27,57","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_023,7,148504752,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met748Leu/c.2242A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9467,125,9625,"0,012987013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,279,Tolerated,"28,21","15,98"
"low bq, low freq, many artifacts, many samples",UPN2_025,7,148504752,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met748Leu/c.2242A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10790,118,10949,"0,0107772399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,279,Tolerated,"27,58","15,24"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_026,7,148504752,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met748Leu/c.2242A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8333,104,8473,"0,012274283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,279,Tolerated,"26,75","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_027,7,148504752,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met748Leu/c.2242A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11263,134,11449,"0,011704079",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,279,Tolerated,"27,36","15,19"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_028,7,148504752,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met748Leu/c.2242A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9011,105,9161,"0,0114616308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,279,Tolerated,"26,95","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_044,7,148504752,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met748Leu/c.2242A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1156,20,1185,"0,0168776371",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,279,Tolerated,"29,44","15,8"
"low bq, low freq, many artifacts, many samples",UPN2_045,7,148504752,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met748Leu/c.2242A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5011,56,5106,"0,0109674892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,279,Tolerated,"28,97","15,18"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_033,7,148504752,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met748Leu/c.2242A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5939,71,6043,"0,0117491312",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,279,Tolerated,"26,97","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_036,7,148504752,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met748Leu/c.2242A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13514,140,13709,"0,0102122693",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,279,Tolerated,28,"16,12"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_037,7,148504752,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met748Leu/c.2242A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9282,105,9429,"0,0111358575",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,279,Tolerated,"26,71","15,31"
"low bq, low freq, many artifacts, many samples",UPN2_052,7,148504752,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met748Leu/c.2242A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5181,65,5272,"0,0123292868",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,279,Tolerated,"28,15","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_038,7,148504752,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met748Leu/c.2242A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13430,161,13645,"0,0117991938",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,279,Tolerated,"27,22","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_039,7,148504752,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met748Leu/c.2242A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),18303,200,18585,"0,0107613667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,279,Tolerated,"27,77","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_053,7,148504752,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met748Leu/c.2242A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8675,108,8833,"0,0122268765",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,279,Tolerated,"28,05","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_056,7,148504752,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met748Leu/c.2242A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2562,28,2603,"0,0107568191",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,279,Tolerated,"28,19","17,14"
"low bq, low freq, many artifacts",UPN2_012,7,148504752,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met748Leu/c.2242A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3322,47,3376,"0,0139218009",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,279,Tolerated,"29,6","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_001,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4224,60,4299,"0,0139567341",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"27,31","15,4"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_014,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8350,169,8548,"0,0197707066",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"23,88","16,2"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_015,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11663,191,11895,"0,0160571669",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"24,61","15,58"
"low bq, bad alignment, many samples",UPN2_016,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5898,137,6058,"0,0226147243",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"23,67","16,02"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_017,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3270,70,3352,"0,0208830549",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"24,05","15,2"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_018,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5947,128,6102,"0,0209767289",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"23,48","15,62"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_019,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7721,152,7899,"0,0192429421",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"23,93","15,71"
"low bq, bad alignment, many samples",UPN2_020,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3659,91,3761,"0,0241956926",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"23,01","15,79"
"low bq, bad alignment, many samples",UPN2_021,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5999,150,6162,"0,0243427459",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"22,97","15,91"
"low bq, low freq, many artifacts, many samples",UPN2_002,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4467,71,4555,"0,0155872667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"27,27","15,18"
"low bq, bad alignment, many samples",UPN2_022,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8647,208,8879,"0,0234260615",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"24,05","15,23"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_023,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9422,173,9618,"0,0179871075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"24,38","16,02"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_041,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1220,20,1249,"0,0160128102",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"25,67","15,1"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_024,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3061,52,3122,"0,0166559898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"24,29","16,46"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_025,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10717,196,10943,"0,0179109933",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"23,53","15,31"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_026,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8284,164,8470,"0,0193624557",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"23,29","15,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_027,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11201,217,11447,"0,0189569319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"23,82","14,88"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8515,151,8699,"0,017358317",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"25,34","15,64"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_028,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8932,197,9155,"0,021518296",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"23,31","15,75"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_043,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6643,97,6766,"0,0143363878",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"25,58","15,41"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_029,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7840,142,8017,"0,0177123612",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"23,71","15,49"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_030,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8412,160,8609,"0,0185852015",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"22,48","15,36"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_031,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5561,105,5682,"0,0184794087",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"24,6","15,46"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4981,97,5106,"0,0189972581",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"25,17","15,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_032,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3415,51,3476,"0,0146720368",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"24,75","16,35"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10746,199,10992,"0,0181040757",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"25,35","15,86"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_033,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5912,115,6043,"0,019030283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"23,12","14,92"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_034,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1901,40,1945,"0,0205655527",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"23,5","16,1"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9994,174,10202,"0,0170554793",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"25,74","14,97"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_048,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4095,68,4181,"0,0162640517",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"25,62","15,16"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_035,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11818,207,12077,"0,0171400182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"24,63","15,63"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_036,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13448,211,13706,"0,0153947176",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"24,28","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_006,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5487,94,5599,"0,0167887123",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"27,03","15,6"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6764,89,6876,"0,0129435718",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"26,23","16,18"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7664,120,7821,"0,0153433065",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"26,32","15,4"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_037,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9200,196,9426,"0,0207935498",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"23,05","14,91"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8101,124,8260,"0,0150121065",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"25,57","16,02"
"low bq, bad alignment, many samples",UPN2_052,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5129,129,5269,"0,0244828241",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"24,6","14,99"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_038,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13305,284,13642,"0,0208180619",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"23,51","15,09"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_039,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),18177,336,18579,"0,0180849346",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"24,14","15,53"
"low bq, bad alignment, many samples",UPN2_053,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8613,196,8833,"0,0221895166",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"24,75","15,19"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8991,128,9153,"0,013984486",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"26,01","15,48"
"low bq, low freq, many artifacts, many samples",UPN2_007,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11729,183,11951,"0,0153125261",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"27,26","15,16"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_008,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13117,243,13403,"0,0181302693",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"26,75","15,58"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_009,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10862,215,11108,"0,0193554195",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"26,6","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_010,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10654,204,10890,"0,0187327824",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"27,14","16,08"
"low bq, low freq, many artifacts, many samples",UPN2_011,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10549,182,10766,"0,0169050715",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"27,39","15,57"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9115,191,9345,"0,0204387373",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"25,7","15,94"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2539,55,2603,"0,021129466",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"24,63","15,93"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8419,130,8581,"0,0151497494",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"26,07","15,52"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_058,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9072,128,9240,"0,0138528139",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"26,23","15,8"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_012,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3294,74,3375,"0,0219259259",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"26,24","15,31"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_040,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8128,141,8306,"0,0169756802",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"24,3","14,94"
low bq,UPN2_013,7,148504753,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu747Asp/c.2241A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2473,56,2540,"0,0220472441",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,114,Tolerated,"27,02","15,89"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_014,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8376,139,8543,"0,0162706309",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"22,87","17,17"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_015,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11698,152,11891,"0,0127827769",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"23,71","17,25"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_016,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5948,91,6057,"0,0150239392",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"22,27","15,93"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_017,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3289,57,3350,"0,0170149254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"22,69","18,25"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_018,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6004,77,6101,"0,0126208818",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"22,18","16,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_019,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7762,108,7895,"0,013679544",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"23,25","15,8"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_020,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3667,75,3758,"0,0199574242",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"21,06","15,41"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_021,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6014,128,6157,"0,0207893455",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"21,04","15,55"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_002,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4485,56,4553,"0,0122995827",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"26,36","14,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_022,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8708,137,8875,"0,0154366197",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"22,55","16,77"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_023,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9437,147,9615,"0,0152886115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"23,35","15,86"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_025,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10722,191,10938,"0,0174620589",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"21,93","16,29"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_026,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8281,163,8463,"0,0192603096",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"21,33","15,57"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_027,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11212,195,11438,"0,017048435",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"22,47","15,72"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8558,121,8704,"0,0139016544",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"24,28","16,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_028,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8961,157,9150,"0,0171584699",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"22,14","17,96"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_043,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6636,91,6765,"0,0134515891",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"25,2","16,8"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_029,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7882,108,8013,"0,0134780981",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"22,92","16,49"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_030,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8450,123,8609,"0,0142873737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"21,82","15,37"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_031,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5588,71,5678,"0,012504403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"23,77","16,92"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_005,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1394,20,1417,"0,014114326",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"26,55","16,2"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4985,85,5101,"0,0166633993",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"24,19","14,52"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_032,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3427,38,3475,"0,0109352518",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"23,76","16,89"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10773,175,10984,"0,0159322651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"24,46","16,69"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_033,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5903,116,6037,"0,0192148418",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"21,62","16,02"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_034,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1897,38,1943,"0,0195573855",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"22,45","18,05"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9995,169,10197,"0,016573502",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"24,74","16,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_048,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4102,67,4180,"0,0160287081",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"24,43","16,18"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_035,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11886,151,12072,"0,0125082836",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"23,74","15,05"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_036,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13457,200,13699,"0,0145996058",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"23,25","16,26"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_006,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5516,70,5597,"0,0125067",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"26,19","15,49"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6717,119,6872,"0,0173166473",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"25,44","17,41"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7643,135,7817,"0,0172700524",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"25,56","16,67"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_037,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9190,195,9422,"0,0206962428",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"21,95","16,2"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8098,122,8256,"0,0147771318",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"24,52","15,38"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5145,101,5266,"0,019179643",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"23,2","15,57"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_038,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13361,233,13632,"0,0170921362",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"22,28","16,88"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_039,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),18254,249,18573,"0,0134065579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"23,45","16,2"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8607,183,8830,"0,0207248018",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"23,21","16,52"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8962,133,9151,"0,0145339307",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"25,51","17,83"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_007,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11742,161,11949,"0,0134739309",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"26,86","15,86"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_008,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13186,177,13399,"0,013209941",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,26,"16,17"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_009,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10896,181,11106,"0,0162974968",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"26,06","15,87"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_010,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10714,141,10886,"0,0129524159",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"26,88","16,8"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_011,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10585,147,10764,"0,0136566332",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"26,92","16,61"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9131,167,9334,"0,0178915792",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"24,64","16,27"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2556,43,2601,"0,016532103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"23,76","18,3"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8441,115,8579,"0,0134048257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"25,42","16,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_058,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9083,112,9238,"0,0121238363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"25,37","15,77"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_012,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3317,50,3376,"0,0148104265",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"25,31","16,12"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_040,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8152,123,8301,"0,0148174919",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"23,16","16,8"
"low bq, bad alignment, low freq, many artifacts",UPN2_013,7,148504754,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu747Val/c.2240A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2491,34,2538,"0,0133963751",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,0,Damaging,"25,97","15,94"
"low bq, bad alignment, many samples",UPN2_089,7,148504755,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu747*/c.2239G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),954,22,976,"0,0225409836",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"22,34",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,7,148504755,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu747*/c.2239G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5203,55,5265,"0,0104463438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,77","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_056,7,148504755,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu747*/c.2239G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2569,28,2601,"0,0107650903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,06",14
"low bq, bad alignment, many samples",UPN2_095,7,148504755,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu747*/c.2239G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),759,31,791,"0,0391908976",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"22,74",14
"low bq, bad alignment, many samples",UPN2_097,7,148504755,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu747*/c.2239G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),727,26,754,"0,0344827586",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"21,77",14
"low bq, bad alignment, many samples",UPN2_100,7,148504755,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu747*/c.2239G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),919,25,945,"0,0264550265",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"22,14","14,52"
"low bq, bad alignment, many samples",UPN2_103,7,148504755,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu747*/c.2239G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),762,21,783,"0,0268199234",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"21,82",14
"low bq, bad alignment, many samples",UPN2_105,7,148504755,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu747*/c.2239G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),807,31,838,"0,0369928401",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"21,87",14
"low bq, bad alignment, many samples",UPN2_108,7,148504755,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu747*/c.2239G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),861,23,884,"0,0260180995",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"22,59",14
"low bq, bad alignment, many samples",UPN2_109,7,148504755,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu747*/c.2239G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),850,24,874,"0,0274599542",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"22,14",14
"low bq, bad alignment",UPN2_111,7,148504755,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu747*/c.2239G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),783,24,809,"0,0296662546",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"22,66",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_014,7,148504756,T,A,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg746Ser/c.2238A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8424,88,8539,"0,0103056564",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,69",Deleterious,1,Damaging,"25,99","15,16"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_016,7,148504756,T,A,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg746Ser/c.2238A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5952,82,6055,"0,0135425268",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,69",Deleterious,1,Damaging,"25,27","15,95"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_017,7,148504756,T,A,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg746Ser/c.2238A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3293,41,3349,"0,0122424604",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,69",Deleterious,1,Damaging,"25,68","15,83"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_018,7,148504756,T,A,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg746Ser/c.2238A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6020,64,6098,"0,0104952443",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,69",Deleterious,1,Damaging,"25,02","15,31"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_020,7,148504756,T,A,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg746Ser/c.2238A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3697,44,3757,"0,0117114719",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,69",Deleterious,1,Damaging,"24,07",15
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_021,7,148504756,T,A,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg746Ser/c.2238A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6064,75,6154,"0,0121871953",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,69",Deleterious,1,Damaging,"23,86","15,23"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_022,7,148504756,T,A,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg746Ser/c.2238A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8740,107,8872,"0,0120604148",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,69",Deleterious,1,Damaging,"25,54","16,1"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_024,7,148504756,T,A,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg746Ser/c.2238A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3070,39,3121,"0,0124959949",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,69",Deleterious,1,Damaging,"25,91","16,72"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_025,7,148504756,T,A,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg746Ser/c.2238A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10759,140,10933,"0,0128052685",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,69",Deleterious,1,Damaging,"24,96","15,35"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_026,7,148504756,T,A,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg746Ser/c.2238A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8319,118,8462,"0,0139446939",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,69",Deleterious,1,Damaging,"24,22","15,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_027,7,148504756,T,A,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg746Ser/c.2238A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11256,132,11433,"0,0115455261",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,69",Deleterious,1,Damaging,"25,41","15,78"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,7,148504756,T,A,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg746Ser/c.2238A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8581,90,8698,"0,0103472063",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,69",Deleterious,1,Damaging,"26,46","16,06"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_028,7,148504756,T,A,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg746Ser/c.2238A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8998,124,9146,"0,0135578395",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,69",Deleterious,1,Damaging,"24,9","15,74"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_029,7,148504756,T,A,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg746Ser/c.2238A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7900,84,8011,"0,0104855823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,69",Deleterious,1,Damaging,"25,97","15,95"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,7,148504756,T,A,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg746Ser/c.2238A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5024,63,5100,"0,0123529412",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,69",Deleterious,1,Damaging,"26,4","17,92"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_032,7,148504756,T,A,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg746Ser/c.2238A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3420,43,3475,"0,0123741007",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,69",Deleterious,1,Damaging,"26,49","16,95"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,7,148504756,T,A,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg746Ser/c.2238A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10819,122,10982,"0,0111090876",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,69",Deleterious,1,Damaging,"26,52","17,48"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_033,7,148504756,T,A,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg746Ser/c.2238A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5941,73,6036,"0,0120941021",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,69",Deleterious,1,Damaging,"24,58","15,29"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,7,148504756,T,A,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg746Ser/c.2238A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10046,104,10190,"0,0102060844",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,69",Deleterious,1,Damaging,"26,79","16,05"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_048,7,148504756,T,A,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg746Ser/c.2238A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4112,48,4175,"0,011497006",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,69",Deleterious,1,Damaging,"26,86","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_049,7,148504756,T,A,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg746Ser/c.2238A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6770,75,6869,"0,0109186199",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,69",Deleterious,1,Damaging,"27,76","17,36"
"low bq, low freq, many artifacts, many samples",UPN2_050,7,148504756,T,A,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg746Ser/c.2238A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7711,85,7816,"0,0108751279",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,69",Deleterious,1,Damaging,"27,75","16,96"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_037,7,148504756,T,A,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg746Ser/c.2238A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9279,123,9421,"0,0130559389",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,69",Deleterious,1,Damaging,"24,82","15,11"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,7,148504756,T,A,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg746Ser/c.2238A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5177,67,5263,"0,0127303819",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,69",Deleterious,1,Damaging,"25,33","15,18"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_038,7,148504756,T,A,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg746Ser/c.2238A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13428,171,13628,"0,0125476959",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,69",Deleterious,1,Damaging,"25,24","15,19"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,7,148504756,T,A,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg746Ser/c.2238A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8681,118,8826,"0,0133695898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,69",Deleterious,1,Damaging,"25,36","15,39"
"low bq, low freq, many artifacts, many samples",UPN2_054,7,148504756,T,A,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg746Ser/c.2238A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9019,98,9151,"0,0107092121",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,69",Deleterious,1,Damaging,"27,62","16,57"
"low bq, low freq, many artifacts, many samples",UPN2_008,7,148504756,T,A,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg746Ser/c.2238A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13196,158,13395,"0,0117954461",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,69",Deleterious,1,Damaging,"28,25","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_009,7,148504756,T,A,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg746Ser/c.2238A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10952,117,11104,"0,0105367435",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,69",Deleterious,1,Damaging,"28,02","15,62"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,7,148504756,T,A,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg746Ser/c.2238A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9196,105,9331,"0,0112528132",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,69",Deleterious,1,Damaging,"26,93","15,43"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,7,148504756,T,A,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg746Ser/c.2238A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2561,35,2601,"0,0134563629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,69",Deleterious,1,Damaging,"25,81",14
"low bq, low freq, many artifacts, many samples",UPN2_012,7,148504756,T,A,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg746Ser/c.2238A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3329,39,3375,"0,0115555556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,69",Deleterious,1,Damaging,"27,58","16,26"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_040,7,148504756,T,A,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg746Ser/c.2238A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8181,94,8299,"0,0113266659",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,69",Deleterious,1,Damaging,"26,07","15,32"
"low bq, low freq, many artifacts",UPN2_013,7,148504756,T,A,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg746Ser/c.2238A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2500,28,2537,"0,0110366575",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,69",Deleterious,1,Damaging,"28,47","15,68"
"low bq, bad alignment, low freq, many artifacts",UPN2_052,7,148504757,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg746Ile/c.2237G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5203,56,5262,"0,0106423413",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,42",Deleterious,0,Damaging,"26,86",14
"low bq, low freq, many artifacts, many samples",UPN2_001,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4241,46,4299,"0,0107001628",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,26","16,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_014,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8389,127,8539,"0,0148729359",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"23,78","15,11"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_015,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11658,175,11889,"0,0147194886",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"24,45","14,95"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_016,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5932,101,6055,"0,0166804294",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"23,31","15,16"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_017,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3260,72,3348,"0,0215053763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"23,67",16
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_018,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5978,91,6096,"0,0149278215",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"23,09","15,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_019,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7749,115,7891,"0,0145735648",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"23,97","14,7"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_020,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3672,69,3757,"0,0183657173",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"22,27","15,74"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_021,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6009,123,6153,"0,0199902487",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"22,05","14,9"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_002,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4486,52,4553,"0,0114210411",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,63","14,42"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_022,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8665,174,8870,"0,0196166855",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"23,65","15,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_023,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9420,151,9610,"0,0157127992",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"24,17","15,36"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_024,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3057,55,3121,"0,0176225569",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"23,85","14,64"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_025,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10713,180,10931,"0,0164669289",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"23,05","15,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_026,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8254,177,8461,"0,0209195131",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"22,42","15,47"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_027,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11191,192,11430,"0,0167979003",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"23,23","14,97"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8522,133,8693,"0,0152996664",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"24,93","15,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_028,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8943,168,9144,"0,0183727034",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"22,91","15,3"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_043,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6631,86,6759,"0,0127237757",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,62","15,44"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_044,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1156,24,1185,"0,0202531646",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,44","18,96"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_029,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7841,117,8010,"0,0146067416",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"23,69","15,26"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_030,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8402,158,8601,"0,018369957",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"22,54","15,9"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_031,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5576,83,5677,"0,0146203981",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"24,56","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_005,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1386,25,1416,"0,0176553672",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,25","16,64"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5006,77,5099,"0,0151010002",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,03","15,49"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_032,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3421,37,3474,"0,0106505469",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"24,48","17,49"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10788,152,10978,"0,0138458736",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,04","15,66"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_033,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5880,121,6034,"0,0200530328",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"22,86","16,13"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_034,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1908,30,1943,"0,0154400412",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"23,43","16,9"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10007,130,10187,"0,0127613625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,45","16,47"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_048,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4098,58,4174,"0,0138955438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,17","15,36"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_035,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11835,190,12071,"0,0157402038",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"24,56","15,43"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_036,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13411,205,13686,"0,0149788105",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"24,17","15,69"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_006,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5489,73,5593,"0,0130520293",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,61","14,9"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6726,97,6868,"0,0141234712",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,13","15,97"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7681,95,7813,"0,0121592218",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,18","16,37"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_037,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9213,173,9418,"0,0183690805",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"22,89","14,73"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8088,110,8253,"0,0133284866",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,21","15,36"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5139,101,5262,"0,0191942227",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"24,06","14,4"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_038,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13297,253,13624,"0,0185701703",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"23,33","15,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_039,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),18203,284,18567,"0,0152959552",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"24,17","15,48"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8629,152,8826,"0,0172218446",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"24,2","15,55"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8971,122,9150,"0,0133333333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,07","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_007,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11734,151,11946,"0,0126402143",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,19","15,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_008,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13157,202,13394,"0,0150813797",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,51","14,89"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_009,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10892,169,11104,"0,0152197406",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,44","15,7"
"low bq, low freq, many artifacts, many samples",UPN2_010,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10692,155,10884,"0,0142410878",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,31","15,34"
"low bq, low freq, many artifacts, many samples",UPN2_011,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10577,138,10760,"0,0128252788",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,52","15,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9139,138,9330,"0,0147909968",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,45","16,49"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2531,55,2600,"0,0211538462",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"24,57","15,53"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8412,122,8574,"0,0142290646",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,16","15,49"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_058,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9065,119,9231,"0,0128913444",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,27","16,01"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_012,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3309,53,3375,"0,0157037037",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,8","14,42"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_040,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8138,139,8297,"0,0167530433",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"24,11","15,5"
"low bq, bad alignment, low freq, many artifacts",UPN2_013,7,148504758,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg746*/c.2236A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2490,32,2537,"0,0126133228",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,38","15,38"
"low bq, bad alignment, many samples",UPN2_001,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4179,103,4299,"0,0239590602",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"23,07","14,39"
"low bq, bad alignment, many samples",UPN2_014,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8300,204,8538,"0,0238931834",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"20,56","14,73"
"low bq, bad alignment, many samples",UPN2_015,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11531,313,11886,"0,0263335016",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"21,2","15,06"
"low bq, bad alignment, many samples",UPN2_016,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5839,193,6053,"0,0318850157",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"20,12","14,67"
"low bq, bad alignment, many samples",UPN2_017,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3242,93,3348,"0,0277777778",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"20,36","15,3"
"low bq, bad alignment, many samples",UPN2_018,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5891,184,6094,"0,0301936331",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"19,86","14,99"
"low bq, bad alignment, many samples",UPN2_019,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7653,200,7890,"0,0253485425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"20,58","14,93"
"low bq, bad alignment, many samples",UPN2_020,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3603,137,3757,"0,0364652648",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"19,38","14,91"
"low bq, bad alignment, many samples",UPN2_021,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5912,217,6152,"0,0352730819",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"19,23","15,14"
"low bq, bad alignment, many samples",UPN2_002,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4422,114,4553,"0,0250384362",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"22,98","15,17"
"low bq, bad alignment, many samples",UPN2_003,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),954,27,984,"0,0274390244",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"23,3","14,52"
"low bq, bad alignment, many samples",UPN2_022,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8572,266,8869,"0,0299921073",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"20,34","14,59"
"low bq, bad alignment, many samples",UPN2_023,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9327,262,9607,"0,027271781",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"20,84","15,26"
"low bq, bad alignment, many samples",UPN2_041,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1212,31,1247,"0,0248596632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"22,26","15,06"
"low bq, bad alignment, many samples",UPN2_024,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3035,69,3121,"0,0221082986",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"20,65","14,9"
"low bq, bad alignment, many samples",UPN2_025,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10554,338,10930,"0,0309240622",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"19,88","15,11"
"low bq, bad alignment, many samples",UPN2_026,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8137,290,8458,"0,0342870655",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"19,51","14,56"
"low bq, bad alignment, many samples",UPN2_027,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11019,370,11430,"0,0323709536",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"20,19","14,91"
"low bq, bad alignment, many samples",UPN2_042,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8432,213,8692,"0,0245052922",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"21,83","14,83"
"low bq, bad alignment, many samples",UPN2_028,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8811,302,9141,"0,0330379608",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"19,9","14,87"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_043,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6583,143,6758,"0,0211601065",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"22,29","14,5"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_044,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1156,21,1185,"0,017721519",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"22,17","15,48"
"low bq, bad alignment, many samples",UPN2_029,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7755,230,8010,"0,0287141074",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"20,41","14,5"
"low bq, bad alignment, many samples",UPN2_030,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8296,272,8600,"0,031627907",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"19,38","14,46"
"low bq, bad alignment, many samples",UPN2_031,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5527,135,5676,"0,0237843552",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"21,08","15,27"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_005,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1393,21,1416,"0,0148305085",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"22,85",14
"low bq, bad alignment, many samples",UPN2_045,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4947,129,5096,"0,0253139717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"21,75","14,17"
"low bq, bad alignment, many samples",UPN2_032,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3381,86,3474,"0,0247553253",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"21,17","15,44"
"low bq, bad alignment, many samples",UPN2_046,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10629,290,10975,"0,0264236902",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"21,91","14,24"
"low bq, bad alignment, many samples",UPN2_033,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5829,187,6033,"0,0309961876",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"19,63","14,63"
"low bq, bad alignment, many samples",UPN2_034,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1877,59,1943,"0,0303654143",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"20,43","15,25"
"low bq, bad alignment, many samples",UPN2_047,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9883,259,10183,"0,0254345478",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"22,24","15,32"
"low bq, bad alignment, many samples",UPN2_048,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4059,100,4173,"0,0239635754",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"21,96","14,87"
"low bq, bad alignment, many samples",UPN2_035,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11732,296,12071,"0,0245215806",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"21,1","15,02"
"low bq, bad alignment, many samples",UPN2_036,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13277,340,13680,"0,0248538012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"20,79","14,91"
"low bq, bad alignment, many samples",UPN2_006,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5435,145,5593,"0,0259252637",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"22,77","15,27"
"low bq, bad alignment, many samples",UPN2_049,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6666,179,6868,"0,0260629004",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"22,67","14,94"
"low bq, bad alignment, many samples",UPN2_050,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7592,193,7813,"0,024702419",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"22,89","15,23"
"low bq, bad alignment, many samples",UPN2_037,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9062,313,9416,"0,0332412914",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"19,78","14,44"
"low bq, bad alignment, many samples",UPN2_051,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7992,220,8252,"0,0266602036",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"22,04","15,84"
"low bq, bad alignment, many samples",UPN2_052,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5077,158,5261,"0,0300323132",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"21,23","14,71"
"low bq, bad alignment, many samples",UPN2_038,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13124,461,13622,"0,0338423139",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"20,14","14,81"
"low bq, bad alignment, many samples",UPN2_039,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),18002,498,18565,"0,0268246701",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"20,81","14,69"
"low bq, bad alignment, many samples",UPN2_053,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8532,260,8826,"0,0294584183",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"21,17","15,05"
"low bq, bad alignment, many samples",UPN2_054,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8891,219,9150,"0,0239344262",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"22,64","14,64"
"low bq, bad alignment, many samples",UPN2_007,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11608,291,11946,"0,0243596183",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"23,26","14,8"
"low bq, bad alignment, many samples",UPN2_008,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13009,343,13393,"0,0256103935",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"22,76","14,49"
"low bq, bad alignment, many samples",UPN2_009,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10763,311,11103,"0,0280104476",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"22,77","15,01"
"low bq, bad alignment, many samples",UPN2_010,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10557,293,10883,"0,0269227235",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"23,28","14,52"
"low bq, bad alignment, many samples",UPN2_011,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10445,282,10759,"0,0262106144",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"23,38","14,8"
"low bq, bad alignment, many samples",UPN2_055,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9004,276,9330,"0,0295819936",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"22,11","15,3"
"low bq, bad alignment, many samples",UPN2_056,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2501,94,2600,"0,0361538462",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"21,2","15,03"
"low bq, bad alignment, many samples",UPN2_057,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8311,222,8571,"0,0259012951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"22,79","14,86"
"low bq, bad alignment, many samples",UPN2_058,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8987,211,9231,"0,0228577619",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"22,86","14,86"
"low bq, bad alignment, many samples",UPN2_012,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3282,84,3375,"0,0248888889",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"22,05","14,71"
"low bq, bad alignment, many samples",UPN2_040,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7990,259,8296,"0,031219865",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"20,85","14,82"
"low bq, bad alignment, many samples",UPN2_013,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2438,90,2537,"0,0354749704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"23,04","14,79"
"low bq, bad alignment, low freq, many artifacts",UPN2_082,7,148504759,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu745Asp/c.2235A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1301,26,1329,"0,0195635816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,0,Damaging,"22,44","14,69"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_001,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4231,57,4298,"0,0132619823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"21,04","16,49"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_014,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8338,175,8534,"0,0205062105",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"18,64","16,68"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_015,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11622,218,11883,"0,0183455356",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"19,22","15,83"
"low bq, bad alignment, many samples",UPN2_016,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5892,143,6052,"0,0236285525",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"18,4","16,61"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_017,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3269,68,3348,"0,0203106332",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"18,62","15,18"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_018,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5956,127,6093,"0,020843591",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"18,34","15,02"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_019,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7700,165,7888,"0,0209178499",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"18,79","15,64"
"low bq, bad alignment, many samples",UPN2_020,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3659,90,3757,"0,0239552835",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"18,2","15,04"
"low bq, bad alignment, many samples",UPN2_021,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5993,139,6149,"0,0226053017",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"17,94","15,49"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_002,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4472,70,4553,"0,0153744784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"21,45","16,1"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_003,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),957,21,984,"0,0213414634",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"21,59","16,1"
"low bq, bad alignment, many samples",UPN2_022,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8644,198,8869,"0,0223249521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"18,63","16,29"
"low bq, bad alignment, many samples",UPN2_023,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9360,226,9605,"0,0235294118",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"18,84","16,23"
"low bq, bad alignment, many samples",UPN2_041,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1207,34,1247,"0,027265437",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"20,55","14,65"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_024,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3059,55,3120,"0,0176282051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"19,07","17,45"
"low bq, bad alignment, many samples",UPN2_025,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10641,257,10930,"0,0235132662",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"18,07","15,18"
"low bq, bad alignment, many samples",UPN2_026,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8166,262,8458,"0,0309765902",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"18,34","15,63"
"low bq, bad alignment, many samples",UPN2_027,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11139,259,11430,"0,0226596675",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"18,62","15,75"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8480,185,8690,"0,0212888377",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"20,18","15,97"
"low bq, bad alignment, many samples",UPN2_028,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8856,250,9141,"0,0273493053",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"18,38","16,29"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_043,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6613,130,6756,"0,0192421551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"20,48","15,43"
"low bq, bad alignment, many samples",UPN2_044,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1154,27,1185,"0,0227848101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"20,57",14
"low bq, bad alignment, many samples",UPN2_029,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7807,184,8009,"0,0229741541",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"18,62","15,41"
"low bq, bad alignment, many samples",UPN2_030,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8379,203,8600,"0,0236046512",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"17,94","15,6"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_031,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5573,89,5676,"0,0156800564",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"19,23","16,04"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4986,95,5095,"0,0186457311",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"20,06","16,38"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_032,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3413,54,3474,"0,0155440415",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"19,06","16,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10732,201,10972,"0,0183193584",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"20,14","15,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_033,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5898,123,6032,"0,0203912467",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"18,1","15,11"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_034,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1903,37,1942,"0,0190525232",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"18,73",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9960,189,10181,"0,0185639917",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"20,49","15,81"
"low bq, bad alignment, many samples",UPN2_048,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4065,97,4172,"0,0232502397",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"20,32","15,33"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_035,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11786,253,12071,"0,020959324",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"19,17","16,48"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_036,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13396,252,13679,"0,0184223993",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"18,91","15,79"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_006,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5468,107,5593,"0,0191310567",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"21,2","16,6"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6718,132,6868,"0,019219569",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"21,17","16,65"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7646,135,7812,"0,017281106",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"20,96","16,09"
"low bq, bad alignment, many samples",UPN2_037,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9154,230,9415,"0,0244291025",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"18,47","16,2"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8091,143,8252,"0,0173291323",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"20,45","15,82"
"low bq, bad alignment, many samples",UPN2_052,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5115,126,5261,"0,0239498194",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"19,95","16,18"
"low bq, bad alignment, many samples",UPN2_038,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13235,343,13621,"0,0251817047",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"18,68","15,48"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_039,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),18122,377,18557,"0,0203157838",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"19,12","16,17"
"low bq, bad alignment, many samples",UPN2_053,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8593,196,8826,"0,0222071153",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"19,9","15,66"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8938,168,9149,"0,0183626626",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,21,"16,06"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_007,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11666,254,11945,"0,0212641272",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"21,25","15,63"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_008,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13145,221,13390,"0,0165048544",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"21,2","15,15"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_009,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10853,224,11102,"0,0201765448",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"20,93","15,18"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_010,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10670,189,10884,"0,0173649394",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"21,46","15,84"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_011,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10540,199,10760,"0,0184944238",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"21,55","16,92"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9099,194,9327,"0,0207998285",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"20,57","15,73"
"low bq, bad alignment, many samples",UPN2_056,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2506,79,2598,"0,0304080062",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"20,02","17,82"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8381,162,8568,"0,018907563",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"20,95","16,05"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_058,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9042,159,9227,"0,0172320364",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"20,9","16,44"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_012,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3312,55,3375,"0,0162962963",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"20,49","14,24"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_040,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8097,170,8295,"0,0204942737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"19,03","15,21"
"low bq, bad alignment, low freq, many artifacts",UPN2_013,7,148504760,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu745Val/c.2234A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2472,55,2537,"0,0216791486",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"21,11","16,56"
"low bq, bad alignment, many samples",UPN2_094,7,148504761,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu745*/c.2233G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),719,24,743,"0,0323014805",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"17,61",14
"low bq, bad alignment, many samples",UPN2_095,7,148504761,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu745*/c.2233G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),764,25,790,"0,0316455696",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"18,14","15,6"
"low bq, bad alignment, many samples",UPN2_097,7,148504761,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu745*/c.2233G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),725,25,751,"0,0332889481",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"17,66",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_001,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4227,57,4298,"0,0132619823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"26,2","15,93"
"low bq, bad alignment, many samples",UPN2_014,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8296,201,8531,"0,02356113",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"22,68","16,31"
"low bq, bad alignment, many samples",UPN2_015,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11567,282,11882,"0,0237333782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"23,53","15,35"
"low bq, bad alignment, many samples",UPN2_016,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5877,165,6052,"0,0272637145",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"22,25","15,24"
"low bq, bad alignment, many samples",UPN2_017,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3251,85,3347,"0,0253958769",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"22,52","14,26"
"low bq, bad alignment, many samples",UPN2_018,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5901,173,6089,"0,0284118903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"21,97","15,4"
"low bq, bad alignment, many samples",UPN2_019,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7667,196,7888,"0,0248478702",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"22,81","14,86"
"low bq, bad alignment, many samples",UPN2_020,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3620,118,3757,"0,0314080383",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"21,1","15,12"
"low bq, bad alignment, many samples",UPN2_021,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5929,204,6149,"0,0331761262",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"20,97","14,65"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_002,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4465,80,4553,"0,0175708324",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"25,97","15,27"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_003,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),961,20,984,"0,0203252033",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"26,16","17,65"
"low bq, bad alignment, many samples",UPN2_022,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8585,258,8867,"0,0290966505",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"22,42","14,9"
"low bq, bad alignment, many samples",UPN2_023,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9341,237,9603,"0,0246797876",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"23,07","15,1"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_041,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1210,27,1247,"0,0216519647",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"23,95","15,48"
"low bq, bad alignment, many samples",UPN2_024,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3040,73,3120,"0,0233974359",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"22,54","15,03"
"low bq, bad alignment, many samples",UPN2_025,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10563,339,10926,"0,0310269083",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"21,98","14,75"
"low bq, bad alignment, many samples",UPN2_026,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8127,302,8455,"0,0357185098",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"21,24","14,94"
"low bq, bad alignment, many samples",UPN2_027,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11057,335,11426,"0,0293190968",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"22,26","15,4"
"low bq, bad alignment, many samples",UPN2_089,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),948,23,975,"0,0235897436",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"18,29","14,96"
"low bq, bad alignment, many samples",UPN2_042,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8441,214,8687,"0,0246345113",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"23,8","15,5"
"low bq, bad alignment, many samples",UPN2_028,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8812,293,9137,"0,0320674182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"21,84","15,18"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_043,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6584,135,6752,"0,0199940758",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"24,31","15,4"
"low bq, bad alignment, many samples",UPN2_044,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1152,29,1185,"0,0244725738",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"24,27",14
"low bq, bad alignment, many samples",UPN2_029,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7806,183,8008,"0,0228521479",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"22,54","15,02"
"low bq, bad alignment, many samples",UPN2_030,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8346,233,8598,"0,0270993254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"21,28","14,76"
"low bq, bad alignment, many samples",UPN2_031,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5526,141,5677,"0,0248370618",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"23,55","14,84"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_005,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1388,23,1416,"0,0162429379",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"26,46","15,74"
"low bq, bad alignment, many samples",UPN2_045,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4938,126,5092,"0,0247446976",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"23,69","14,84"
"low bq, bad alignment, many samples",UPN2_032,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3377,87,3474,"0,0250431779",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"23,64","15,47"
"low bq, bad alignment, many samples",UPN2_046,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10695,247,10968,"0,0225200584",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"23,69","15,11"
"low bq, bad alignment, many samples",UPN2_033,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5818,201,6031,"0,0333278063",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"21,61","15,09"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_034,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1897,42,1942,"0,0216271885",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"21,96","14,43"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9929,214,10177,"0,0210278078",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"24,01","15,73"
"low bq, bad alignment, many samples",UPN2_048,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4055,99,4171,"0,0237353153",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"24,06","15,11"
"low bq, bad alignment, many samples",UPN2_035,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11744,292,12069,"0,0241942166",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"23,37","15,3"
"low bq, bad alignment, many samples",UPN2_036,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13279,361,13676,"0,0263966072",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"23,03","15,35"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_006,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5475,100,5593,"0,0178794922",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"25,9","15,5"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6717,120,6868,"0,0174723355",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"25,58","17,57"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7646,132,7809,"0,0169035728",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"25,68","15,51"
"low bq, bad alignment, many samples",UPN2_037,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9071,319,9414,"0,0338857021",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"21,54","15,08"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8064,155,8251,"0,0187856017",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"24,74","15,82"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5125,110,5260,"0,0209125475",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"23,64","15,12"
"low bq, bad alignment, many samples",UPN2_038,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13145,430,13617,"0,0315781743",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"22,03","15,06"
"low bq, bad alignment, many samples",UPN2_039,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),18012,484,18555,"0,0260846133",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"23,01","15,37"
"low bq, bad alignment, many samples",UPN2_053,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8586,206,8821,"0,0233533613",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"23,54","15,24"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8958,147,9146,"0,0160726",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"25,46","16,06"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_007,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11653,242,11943,"0,0202629155",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"25,66","15,35"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_008,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13084,281,13388,"0,0209889453",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"25,01","14,62"
"low bq, bad alignment, many samples",UPN2_009,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10789,280,11100,"0,0252252252",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"24,91","14,98"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_010,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10632,217,10884,"0,019937523",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"25,76","15,46"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_011,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10487,236,10756,"0,0219412421",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"25,87","15,47"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9103,190,9325,"0,0203753351",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"24,88","15,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2534,57,2597,"0,021948402",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"23,8","15,95"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8372,170,8565,"0,0198482195",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"24,94","15,55"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_058,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9017,177,9221,"0,019195315",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"25,2","14,87"
"low bq, bad alignment, many samples",UPN2_012,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3273,89,3376,"0,0263625592",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"24,26","15,09"
"low bq, bad alignment, many samples",UPN2_040,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8041,226,8292,"0,0272551857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"22,93","14,94"
"low bq, bad alignment, many samples",UPN2_013,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2471,57,2537,"0,0224674813",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"24,76","16,4"
"low bq, bad alignment, many samples",UPN2_070,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),609,25,639,"0,0391236307",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"22,14",14
"low bq, bad alignment, many samples",UPN2_072,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),934,24,962,"0,0249480249",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"22,99","14,92"
"low bq, bad alignment, many samples",UPN2_081,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),915,23,943,"0,0243902439",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"22,62",14
"low bq, bad alignment",UPN2_082,7,148504764,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile744Phe/c.2230A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1286,37,1327,"0,0278824416",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,1,Damaging,"23,18",14
"low bq, bad alignment, many samples",UPN2_089,7,148504766,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly743Val/c.2228G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),912,62,975,"0,0635897436",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"18,34",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,7,148504766,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly743Val/c.2228G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8510,153,8687,"0,0176125245",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"22,01","14,81"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_043,7,148504766,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly743Val/c.2228G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6609,119,6751,"0,0176270182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"22,25","14,45"
"low bq, bad alignment, many samples",UPN2_044,7,148504766,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly743Val/c.2228G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1156,27,1185,"0,0227848101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"22,26","14,67"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,7,148504766,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly743Val/c.2228G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4982,92,5090,"0,0180746562",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"21,98","15,02"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,7,148504766,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly743Val/c.2228G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10721,212,10966,"0,0193324822",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"22,29",15
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,7,148504766,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly743Val/c.2228G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9964,188,10171,"0,0184839249",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"22,56","14,78"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_048,7,148504766,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly743Val/c.2228G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4091,75,4168,"0,0179942418",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"22,43","15,31"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,7,148504766,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly743Val/c.2228G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6716,127,6868,"0,018491555",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"23,28","14,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,7,148504766,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly743Val/c.2228G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7651,140,7807,"0,0179326246",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"23,33","14,29"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,7,148504766,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly743Val/c.2228G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8079,147,8249,"0,0178203419",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"22,44","14,89"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,7,148504766,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly743Val/c.2228G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5149,98,5260,"0,0186311787",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"22,21","14,96"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,7,148504766,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly743Val/c.2228G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8630,175,8820,"0,0198412698",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"22,13","14,63"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,7,148504766,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly743Val/c.2228G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8970,150,9145,"0,0164024057",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"23,31","14,49"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,7,148504766,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly743Val/c.2228G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9116,181,9324,"0,0194122694",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"22,84","14,73"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,7,148504766,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly743Val/c.2228G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2534,55,2597,"0,0211782826",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"22,29","14,76"
"low bq, bad alignment, many samples",UPN2_090,7,148504766,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly743Val/c.2228G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),392,32,425,"0,0752941176",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"18,81",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,7,148504766,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly743Val/c.2228G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8423,127,8562,"0,0148329829",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"23,12","14,6"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_058,7,148504766,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly743Val/c.2228G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9046,149,9218,"0,0161640269",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"23,16","14,39"
"low bq, bad alignment, many samples",UPN2_091,7,148504766,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly743Val/c.2228G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),408,24,432,"0,0555555556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"18,8","14,29"
"low bq, bad alignment, many samples",UPN2_093,7,148504766,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly743Val/c.2228G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),565,52,619,"0,084006462",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"18,58",14
"low bq, bad alignment, many samples",UPN2_069,7,148504766,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly743Val/c.2228G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1007,27,1034,"0,0261121857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"23,49","14,81"
"low bq, bad alignment, many samples",UPN2_072,7,148504766,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly743Val/c.2228G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),936,24,961,"0,0249739854",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"23,57","14,75"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_081,7,148504766,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly743Val/c.2228G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),919,20,942,"0,0212314225",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"23,8","14,65"
"low bq, bad alignment, many samples",UPN2_082,7,148504766,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly743Val/c.2228G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1290,33,1327,"0,0248681236",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"22,82",14
"low bq, bad alignment, many samples",UPN2_094,7,148504766,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly743Val/c.2228G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),675,68,743,"0,0915208614",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"18,51","14,1"
"low bq, bad alignment, many samples",UPN2_095,7,148504766,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly743Val/c.2228G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),719,66,790,"0,0835443038",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"19,06",14
"low bq, bad alignment, many samples",UPN2_096,7,148504766,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly743Val/c.2228G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),626,60,687,"0,0873362445",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"18,38","14,12"
"low bq, bad alignment, many samples",UPN2_097,7,148504766,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly743Val/c.2228G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),705,44,751,"0,0585885486",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"18,31","14,66"
"low bq, bad alignment, many samples",UPN2_098,7,148504766,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly743Val/c.2228G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),850,56,906,"0,0618101545",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"19,66","14,36"
"low bq, bad alignment, many samples",UPN2_100,7,148504766,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly743Val/c.2228G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),877,64,941,"0,0680127524",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"19,45","14,56"
"low bq, bad alignment, many samples",UPN2_101,7,148504766,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly743Val/c.2228G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),621,50,674,"0,0741839763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"19,36","14,14"
"low bq, bad alignment, many samples",UPN2_102,7,148504766,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly743Val/c.2228G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),772,52,827,"0,0628778718",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"19,14","14,25"
"low bq, bad alignment, many samples",UPN2_103,7,148504766,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly743Val/c.2228G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),717,64,781,"0,0819462228",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"19,23","14,22"
"low bq, bad alignment, many samples",UPN2_104,7,148504766,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly743Val/c.2228G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),627,40,668,"0,0598802395",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"18,85","14,73"
"low bq, bad alignment, many samples",UPN2_105,7,148504766,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly743Val/c.2228G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),764,68,835,"0,0814371257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"18,47","14,26"
"low bq, bad alignment, many samples",UPN2_106,7,148504766,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly743Val/c.2228G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),534,35,569,"0,0615114236",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"19,17",14
"low bq, bad alignment, many samples",UPN2_107,7,148504766,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly743Val/c.2228G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),694,43,738,"0,0582655827",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"19,51",14
"low bq, bad alignment, many samples",UPN2_108,7,148504766,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly743Val/c.2228G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),833,47,884,"0,0531674208",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"19,24",14
"low bq, bad alignment, many samples",UPN2_109,7,148504766,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly743Val/c.2228G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),824,45,873,"0,0515463918",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"19,12","14,89"
"low bq, bad alignment",UPN2_111,7,148504766,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly743Val/c.2228G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),758,45,808,"0,0556930693",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"19,06",14
"low bq, bad alignment, many samples",UPN2_089,7,148504767,C,A,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly743Cys/c.2227G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),916,56,975,"0,0574358974",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"18,78","14,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,7,148504767,C,A,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly743Cys/c.2227G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8521,136,8684,"0,0156609857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"22,54","14,78"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_043,7,148504767,C,A,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly743Cys/c.2227G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6637,81,6750,"0,012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"22,6","14,77"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,7,148504767,C,A,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly743Cys/c.2227G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4989,82,5089,"0,0161131853",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"22,43","14,27"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,7,148504767,C,A,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly743Cys/c.2227G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10733,187,10965,"0,0170542636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"22,75","15,68"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,7,148504767,C,A,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly743Cys/c.2227G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9988,147,10171,"0,0144528562",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"22,8","14,91"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_048,7,148504767,C,A,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly743Cys/c.2227G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4082,79,4168,"0,0189539347",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"22,7","15,37"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,7,148504767,C,A,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly743Cys/c.2227G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6734,107,6868,"0,0155794991",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"23,69","14,37"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,7,148504767,C,A,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly743Cys/c.2227G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7683,90,7807,"0,0115281158",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"23,48","15,04"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,7,148504767,C,A,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly743Cys/c.2227G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8060,158,8249,"0,0191538368",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"23,09","14,31"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,7,148504767,C,A,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly743Cys/c.2227G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5136,93,5260,"0,0176806084",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"22,85","14,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,7,148504767,C,A,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly743Cys/c.2227G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8617,171,8819,"0,0193899535",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"22,88","14,7"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,7,148504767,C,A,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly743Cys/c.2227G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8978,116,9144,"0,0126859143",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"23,53","14,99"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,7,148504767,C,A,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly743Cys/c.2227G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9106,168,9324,"0,018018018",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"23,28","14,98"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,7,148504767,C,A,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly743Cys/c.2227G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2537,54,2597,"0,0207932229",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"22,78","14,81"
"low bq, bad alignment, many samples",UPN2_090,7,148504767,C,A,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly743Cys/c.2227G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),405,20,425,"0,0470588235",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"18,61",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,7,148504767,C,A,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly743Cys/c.2227G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8417,113,8562,"0,013197851",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"23,26","15,25"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_058,7,148504767,C,A,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly743Cys/c.2227G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9070,103,9218,"0,0111737904",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"23,38","15,46"
"low bq, bad alignment, many samples",UPN2_091,7,148504767,C,A,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly743Cys/c.2227G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),401,31,432,"0,0717592593",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"18,98",14
"low bq, bad alignment, many samples",UPN2_093,7,148504767,C,A,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly743Cys/c.2227G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),586,33,619,"0,0533117932",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"19,02",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_082,7,148504767,C,A,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly743Cys/c.2227G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1300,25,1327,"0,0188394876",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"23,15","14,72"
"low bq, bad alignment, many samples",UPN2_094,7,148504767,C,A,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly743Cys/c.2227G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),697,46,743,"0,0619111709",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"18,83",14
"low bq, bad alignment, many samples",UPN2_095,7,148504767,C,A,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly743Cys/c.2227G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),734,55,790,"0,0696202532",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"19,75","14,33"
"low bq, bad alignment, many samples",UPN2_096,7,148504767,C,A,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly743Cys/c.2227G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),640,46,687,"0,0669577875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"18,63","14,48"
"low bq, bad alignment, many samples",UPN2_097,7,148504767,C,A,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly743Cys/c.2227G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),709,39,750,"0,052",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"18,38",14
"low bq, bad alignment, many samples",UPN2_098,7,148504767,C,A,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly743Cys/c.2227G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),859,43,905,"0,0475138122",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"20,02","14,16"
"low bq, bad alignment, many samples",UPN2_100,7,148504767,C,A,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly743Cys/c.2227G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),873,66,941,"0,0701381509",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"19,53","14,2"
"low bq, bad alignment, many samples",UPN2_101,7,148504767,C,A,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly743Cys/c.2227G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),633,38,674,"0,056379822",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"19,21",14
"low bq, bad alignment, many samples",UPN2_102,7,148504767,C,A,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly743Cys/c.2227G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),785,40,827,"0,0483675937",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"19,29",14
"low bq, bad alignment, many samples",UPN2_103,7,148504767,C,A,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly743Cys/c.2227G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),729,49,781,"0,0627400768",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"19,56",14
"low bq, bad alignment, many samples",UPN2_104,7,148504767,C,A,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly743Cys/c.2227G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),623,45,668,"0,0673652695",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"18,71",14
"low bq, bad alignment, many samples",UPN2_105,7,148504767,C,A,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly743Cys/c.2227G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),767,66,835,"0,0790419162",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,19,14
"low bq, bad alignment, many samples",UPN2_107,7,148504767,C,A,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly743Cys/c.2227G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),704,32,738,"0,0433604336",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"19,25",14
"low bq, bad alignment, many samples",UPN2_108,7,148504767,C,A,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly743Cys/c.2227G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),830,48,884,"0,0542986425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"19,64",14
"low bq, bad alignment, many samples",UPN2_109,7,148504767,C,A,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly743Cys/c.2227G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),833,38,873,"0,0435280641",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"19,03",14
"low bq, bad alignment, many samples",UPN2_110,7,148504767,C,A,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly743Cys/c.2227G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),428,26,454,"0,0572687225",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"18,89",14
"low bq, bad alignment",UPN2_111,7,148504767,C,A,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly743Cys/c.2227G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),758,48,808,"0,0594059406",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"19,71",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_014,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8326,177,8524,"0,0207648991",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"24,81","14,87"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_015,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11576,260,11871,"0,0219021144",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"24,96","14,82"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_016,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5898,130,6050,"0,0214876033",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"24,63","14,88"
"low bq, bad alignment, many samples",UPN2_017,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3259,76,3345,"0,0227204783",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"24,6","16,67"
"low bq, bad alignment, many samples",UPN2_018,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5939,138,6085,"0,0226787182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"24,28","15,12"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_019,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7723,149,7882,"0,0189038315",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"24,9","15,68"
"low bq, bad alignment, many samples",UPN2_020,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3637,111,3754,"0,0295684603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"23,33","14,36"
"low bq, bad alignment, many samples",UPN2_021,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5947,180,6142,"0,0293064148",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"23,2","15,01"
"low bq, bad alignment, many samples",UPN2_022,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8571,261,8852,"0,0294848622",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"23,98","14,83"
"low bq, bad alignment, many samples",UPN2_023,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9337,231,9589,"0,0240901032",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"24,63","15,19"
"low bq, bad alignment, many samples",UPN2_024,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3034,81,3118,"0,0259781911",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"24,29","14,22"
"low bq, bad alignment, many samples",UPN2_025,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10544,348,10911,"0,0318944185",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"23,42","15,09"
"low bq, bad alignment, many samples",UPN2_026,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8106,323,8445,"0,0382474837",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"22,58","14,84"
"low bq, bad alignment, many samples",UPN2_027,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11054,338,11416,"0,0296075683",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"23,73","14,95"
"low bq, bad alignment, many samples",UPN2_042,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8451,202,8674,"0,0232879871",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"25,02","15,1"
"low bq, bad alignment, many samples",UPN2_028,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8816,285,9123,"0,0312397238",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"23,18",15
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_043,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6605,121,6747,"0,0179338965",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"25,68","14,88"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_044,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1157,25,1184,"0,0211148649",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"25,22","14,88"
"low bq, bad alignment, many samples",UPN2_029,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7780,209,8004,"0,026111944",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,24,"15,1"
"low bq, bad alignment, many samples",UPN2_030,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8320,244,8588,"0,0284117373",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"22,51","14,75"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_031,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5550,107,5672,"0,018864598",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"25,07","14,44"
"low bq, bad alignment, many samples",UPN2_045,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4959,114,5086,"0,0224144711",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"24,78","15,21"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_032,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3409,60,3474,"0,0172711572",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"24,91","15,92"
"low bq, bad alignment, many samples",UPN2_046,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10676,247,10947,"0,0225632593",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"25,06",15
"low bq, bad alignment, many samples",UPN2_033,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5817,198,6025,"0,0328630705",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"23,02","15,03"
"low bq, bad alignment, many samples",UPN2_034,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1890,45,1940,"0,0231958763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"23,2","14,89"
"low bq, bad alignment, many samples",UPN2_047,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9890,242,10161,"0,0238165535",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"25,28","14,6"
"low bq, bad alignment, many samples",UPN2_048,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4050,105,4160,"0,0252403846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"25,08","15,73"
"low bq, bad alignment, many samples",UPN2_035,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11752,284,12057,"0,0235547815",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"24,91","15,31"
"low bq, bad alignment, many samples",UPN2_036,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13308,323,13657,"0,023650875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"24,55","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_006,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5518,57,5591,"0,0101949562",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"28,5","15,86"
"low bq, low freq, many artifacts, many samples",UPN2_049,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6755,97,6864,"0,0141317016",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"27,97","16,19"
"low bq, low freq, many artifacts, many samples",UPN2_050,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7685,99,7803,"0,0126874279",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"28,03","15,77"
"low bq, bad alignment, many samples",UPN2_037,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9083,299,9401,"0,0318051271",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"22,69","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_051,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8139,87,8246,"0,01055057",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"27,32","14,92"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5148,89,5254,"0,0169394747",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"26,39",14
"low bq, bad alignment, many samples",UPN2_038,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13079,491,13606,"0,0360870204",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"23,36","15,17"
"low bq, bad alignment, many samples",UPN2_039,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),18076,424,18538,"0,0228719387",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"24,49","15,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8649,145,8813,"0,0164529672",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"26,37","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_054,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9020,97,9143,"0,0106092092",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"28,01","17,15"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_007,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11717,201,11941,"0,0168327611",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"26,81","14,82"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_008,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13118,246,13381,"0,0183842762",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"26,27","14,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_009,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10853,219,11092,"0,0197439596",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"26,25","14,65"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_010,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10689,163,10882,"0,0149788642",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"26,78","15,52"
"low bq, low freq, many artifacts, many samples",UPN2_011,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10548,190,10753,"0,0176694876",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"27,17","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_055,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9148,153,9320,"0,016416309",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"27,34","15,43"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2552,40,2596,"0,0154083205",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"26,68","14,18"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8363,165,8558,"0,0192802057",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"26,18","15,42"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_058,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9049,144,9211,"0,0156334817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"26,62","15,08"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_012,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3298,67,3373,"0,0198636229",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"25,65","14,27"
"low bq, bad alignment, many samples",UPN2_040,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8045,220,8287,"0,0265476047",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"24,46","14,56"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_013,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2480,54,2537,"0,0212849823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"26,38","15,15"
"low bq, bad alignment, many samples",UPN2_081,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),919,21,941,"0,0223166844",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"23,98",14
"low bq, bad alignment, low freq, many artifacts",UPN2_082,7,148504772,T,A,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr741Phe/c.2222A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1303,24,1327,"0,0180859081",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,6",Neutral,655,Tolerated,"25,28",14
"low bq, low freq, many artifacts, many samples",UPN2_001,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4222,60,4299,"0,0139567341",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"27,51","16,43"
"low bq, bad alignment, many samples",UPN2_014,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8242,255,8519,"0,0299330907",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"23,24","15,65"
"low bq, bad alignment, many samples",UPN2_015,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11428,393,11867,"0,0331170473",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"23,07","15,04"
"low bq, bad alignment, many samples",UPN2_016,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5858,166,6047,"0,0274516289",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"22,89","15,02"
"low bq, bad alignment, many samples",UPN2_017,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3218,107,3341,"0,0320263394",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"22,9","15,3"
"low bq, bad alignment, many samples",UPN2_018,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5916,152,6083,"0,0249876706",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"22,49","14,9"
"low bq, bad alignment, many samples",UPN2_019,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7627,228,7879,"0,0289376824",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"23,21","15,66"
"low bq, bad alignment, many samples",UPN2_020,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3620,121,3753,"0,032240874",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"22,2","14,81"
"low bq, bad alignment, many samples",UPN2_021,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5935,179,6138,"0,0291625937",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"21,7","16,15"
"low bq, low freq, many artifacts, many samples",UPN2_003,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),956,20,984,"0,0203252033",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"27,5",16
"low bq, bad alignment, many samples",UPN2_022,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8486,336,8846,"0,0379832693",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"22,3","15,56"
"low bq, bad alignment, many samples",UPN2_023,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9200,351,9582,"0,0366311835",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"22,96","15,11"
"low bq, bad alignment, many samples",UPN2_041,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1201,41,1245,"0,0329317269",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"23,09","17,02"
"low bq, bad alignment, many samples",UPN2_024,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2992,109,3117,"0,034969522",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"22,84","15,6"
"low bq, bad alignment, many samples",UPN2_025,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10454,409,10904,"0,0375091709",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"21,91","15,06"
"low bq, bad alignment, many samples",UPN2_026,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8093,323,8440,"0,0382701422",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"21,3","14,79"
"low bq, bad alignment, many samples",UPN2_027,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10919,446,11410,"0,0390885188",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"22,15","15,17"
"low bq, bad alignment, many samples",UPN2_042,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8348,292,8671,"0,03367547",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"22,85","15,72"
"low bq, bad alignment, many samples",UPN2_028,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8722,366,9115,"0,040153593",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"21,7","15,48"
"low bq, bad alignment, many samples",UPN2_043,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6508,211,6746,"0,0312777942",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"23,34","15,39"
"low bq, bad alignment, many samples",UPN2_044,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1141,39,1184,"0,0329391892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"23,5","14,74"
"low bq, bad alignment, many samples",UPN2_029,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7637,336,7999,"0,0420052507",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"22,13","15,1"
"low bq, bad alignment, many samples",UPN2_030,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8217,335,8577,"0,0390579457",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"20,88","15,16"
"low bq, bad alignment, many samples",UPN2_031,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5461,182,5668,"0,0321100917",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"23,26","14,77"
"low bq, bad alignment, many samples",UPN2_045,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4904,167,5085,"0,0328416912",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"22,83","15,96"
"low bq, bad alignment, many samples",UPN2_032,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3341,113,3471,"0,0325554595",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"23,15","15,95"
"low bq, bad alignment, many samples",UPN2_046,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10565,324,10933,"0,0296350498",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"23,02","14,91"
"low bq, bad alignment, many samples",UPN2_033,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5762,233,6017,"0,0387236164",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"21,56","15,14"
"low bq, bad alignment, many samples",UPN2_034,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1867,68,1940,"0,0350515464",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"21,93","14,97"
"low bq, bad alignment, many samples",UPN2_047,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9817,303,10153,"0,029843396",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"23,05","15,46"
"low bq, bad alignment, many samples",UPN2_048,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4020,127,4154,"0,0305729417",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"22,98","14,87"
"low bq, bad alignment, many samples",UPN2_035,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11589,423,12051,"0,0351008215",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"22,88","15,65"
"low bq, bad alignment, many samples",UPN2_036,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13080,504,13645,"0,0369366068",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"22,59","15,18"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_006,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5511,61,5591,"0,0109103917",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"26,8",17
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6710,116,6859,"0,0169120863",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"25,72","15,19"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7619,139,7800,"0,0178205128",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"25,79","16,41"
"low bq, bad alignment, many samples",UPN2_037,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8976,396,9399,"0,0421321417",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"21,34","14,88"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8098,116,8243,"0,0140725464",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"25,23","17,34"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5134,101,5251,"0,0192344315",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"24,3","15,88"
"low bq, bad alignment, many samples",UPN2_038,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),12996,551,13597,"0,0405236449",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"21,93","14,82"
"low bq, bad alignment, many samples",UPN2_039,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),17735,703,18518,"0,037963063",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"22,59","15,16"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8601,173,8810,"0,0196367764",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"24,27","17,06"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8959,158,9141,"0,017284761",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"25,66","16,78"
"low bq, bad alignment, many samples",UPN2_007,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11618,279,11934,"0,0233785822",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"25,37","15,41"
"low bq, bad alignment, many samples",UPN2_008,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13000,336,13378,"0,0251158619",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"24,68","15,54"
"low bq, bad alignment, many samples",UPN2_009,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10793,265,11089,"0,0238975561",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"24,72","15,21"
"low bq, bad alignment, many samples",UPN2_010,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10549,286,10880,"0,0262867647",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"25,42","15,74"
"low bq, bad alignment, many samples",UPN2_011,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10441,269,10750,"0,0250232558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"25,54","15,48"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9116,171,9317,"0,0183535473",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"25,23","16,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2540,36,2591,"0,0138942493",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"24,62","16,22"
"low bq, bad alignment, many samples",UPN2_057,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8266,248,8553,"0,028995674",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"23,88","16,11"
"low bq, bad alignment, many samples",UPN2_058,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8900,271,9205,"0,0294405215",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"24,07","16,56"
"low bq, bad alignment, many samples",UPN2_012,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3276,95,3373,"0,0281648384",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"23,99","15,49"
"low bq, bad alignment, many samples",UPN2_040,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7974,287,8285,"0,0346409173",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"22,72","15,07"
"low bq, bad alignment, many samples",UPN2_013,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2444,80,2535,"0,0315581854",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"25,29","15,23"
"low bq, bad alignment, many samples",UPN2_069,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1005,26,1032,"0,0251937984",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"23,74","15,69"
"low bq, bad alignment, many samples",UPN2_075,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),644,22,667,"0,0329835082",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"23,33","15,82"
"low bq, bad alignment, many samples",UPN2_081,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),904,33,941,"0,0350690755",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"22,92","14,21"
"low bq, bad alignment",UPN2_082,7,148504775,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys740Met/c.2219A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1277,43,1323,"0,0325018896",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"23,24","14,58"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_001,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4243,47,4298,"0,0109353188",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,28","15,23"
"low bq, bad alignment, many samples",UPN2_014,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8294,203,8518,"0,0238318854",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"22,94","16,88"
"low bq, bad alignment, many samples",UPN2_015,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11479,349,11864,"0,0294167229",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"22,89","15,8"
"low bq, bad alignment, many samples",UPN2_016,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5830,197,6041,"0,032610495",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"21,4","15,2"
"low bq, bad alignment, many samples",UPN2_017,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3218,110,3341,"0,0329242742",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"21,33","16,57"
"low bq, bad alignment, many samples",UPN2_018,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5876,190,6083,"0,0312345882",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"21,07","15,1"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_019,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7692,164,7878,"0,0208174664",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"22,95","15,71"
"low bq, bad alignment, many samples",UPN2_020,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3553,182,3751,"0,0485203946",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"19,05","15,33"
"low bq, bad alignment, many samples",UPN2_021,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5800,310,6135,"0,0505297474",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"19,03","15,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_002,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4469,68,4551,"0,014941771",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,61","16,4"
"low bq, bad alignment, many samples",UPN2_022,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8436,376,8841,"0,0425291257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"20,98","15,21"
"low bq, bad alignment, many samples",UPN2_023,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9281,251,9577,"0,0262086248",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"22,47","16,09"
"low bq, bad alignment, many samples",UPN2_041,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1202,39,1245,"0,0313253012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"21,75","15,46"
"low bq, bad alignment, many samples",UPN2_024,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2987,116,3117,"0,0372152711",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"21,56","15,07"
"low bq, bad alignment, many samples",UPN2_025,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10340,537,10901,"0,0492615356",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"20,58","14,97"
"low bq, bad alignment, many samples",UPN2_026,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7871,535,8433,"0,0634412427",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"18,75","15,27"
"low bq, bad alignment, many samples",UPN2_027,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10858,493,11403,"0,0432342366",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"20,87","15,35"
"low bq, bad alignment, many samples",UPN2_042,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8247,388,8667,"0,0447675089",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"21,64","15,61"
"low bq, bad alignment, many samples",UPN2_028,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8682,403,9112,"0,0442273924",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"20,4","15,35"
"low bq, bad alignment, many samples",UPN2_043,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6538,184,6743,"0,0272875575",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"22,85","17,28"
"low bq, bad alignment, many samples",UPN2_044,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1148,33,1184,"0,0278716216",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"22,94","16,42"
"low bq, bad alignment, many samples",UPN2_029,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7759,215,7996,"0,0268884442",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"22,11","15,79"
"low bq, bad alignment, many samples",UPN2_030,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8239,305,8575,"0,0355685131",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"20,89","15,88"
"low bq, bad alignment, many samples",UPN2_031,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5519,130,5666,"0,0229438758",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"23,1","15,65"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_005,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1388,24,1416,"0,0169491525",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,65","20,62"
"low bq, bad alignment, many samples",UPN2_045,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4879,188,5082,"0,0369933097",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"21,33","15,3"
"low bq, bad alignment, many samples",UPN2_032,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3374,89,3469,"0,0256558086",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"23,01","15,7"
"low bq, bad alignment, many samples",UPN2_046,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10441,443,10920,"0,0405677656",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"21,64","15,38"
"low bq, bad alignment, many samples",UPN2_033,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5684,314,6014,"0,0522115065",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"20,22","15,34"
"low bq, bad alignment, many samples",UPN2_034,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1843,96,1940,"0,0494845361",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"20,87","15,05"
"low bq, bad alignment, many samples",UPN2_047,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9731,385,10145,"0,0379497289",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"21,88","15,48"
"low bq, bad alignment, many samples",UPN2_048,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3980,157,4153,"0,0378039971",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"21,78","15,41"
"low bq, bad alignment, many samples",UPN2_035,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11648,361,12050,"0,0299585062",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"22,78","15,81"
"low bq, bad alignment, many samples",UPN2_036,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13185,409,13640,"0,0299853372",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"22,39","15,8"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_006,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5468,107,5590,"0,0191413238",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,51","20,12"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6674,146,6858,"0,0212890055",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"24,85","17,3"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7598,163,7798,"0,0209027956",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,1","18,26"
"low bq, bad alignment, many samples",UPN2_037,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8864,495,9397,"0,0526763861",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"20,08","15,41"
"low bq, bad alignment, many samples",UPN2_051,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7991,213,8238,"0,0258557902",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"23,51","16,34"
"low bq, bad alignment, many samples",UPN2_052,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5061,171,5248,"0,0325838415",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"21,82","15,87"
"low bq, bad alignment, many samples",UPN2_038,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),12917,634,13591,"0,0466485174",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"20,63","15,75"
"low bq, bad alignment, many samples",UPN2_039,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),17862,580,18511,"0,0313327211",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"22,52","15,87"
"low bq, bad alignment, many samples",UPN2_053,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8466,288,8801,"0,0327235541",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"21,72","15,88"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8929,177,9139,"0,0193675457",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"24,72","17,44"
"low bq, bad alignment, many samples",UPN2_007,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11623,273,11929,"0,0228854053",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"24,55","16,03"
"low bq, bad alignment, many samples",UPN2_008,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),12962,379,13376,"0,0283343301",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"23,31","15,42"
"low bq, bad alignment, many samples",UPN2_009,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10729,323,11082,"0,0291463635",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"23,18","15,42"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_010,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10626,232,10879,"0,0213254895",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"24,63","16,14"
"low bq, bad alignment, many samples",UPN2_011,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10471,246,10749,"0,0228858498",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"24,82","15,8"
"low bq, bad alignment, many samples",UPN2_055,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9033,244,9317,"0,0261886873",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"23,78","16,95"
"low bq, bad alignment, many samples",UPN2_056,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2514,64,2589,"0,0247199691",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"22,86",16
"low bq, bad alignment, many samples",UPN2_057,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8257,259,8547,"0,0303030303",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"23,25","15,97"
"low bq, bad alignment, many samples",UPN2_058,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8895,268,9199,"0,0291336015",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"23,46","16,8"
"low bq, bad alignment, many samples",UPN2_012,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3248,115,3372,"0,0341043891",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"22,67","14,66"
"low bq, bad alignment, many samples",UPN2_040,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7961,291,8279,"0,0351491726",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,22,"15,32"
"low bq, bad alignment, many samples",UPN2_013,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2447,73,2532,"0,0288309637",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"23,03","18,07"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_069,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1012,20,1032,"0,019379845",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"24,8","15,1"
"low bq, bad alignment, many samples",UPN2_081,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),914,23,939,"0,0244941427",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"23,97","21,3"
"low bq, bad alignment, low freq, many artifacts",UPN2_082,7,148504776,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys740*/c.2218A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1294,26,1323,"0,0196523054",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"23,73","14,85"
"low bq, bad alignment, low freq, many artifacts",UPN2_082,7,148504779,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu739Val/c.2215C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),1291,24,1320,"0,0181818182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,4",Neutral,73,Tolerated,"21,23",14
"low bq, bad alignment, low freq, many artifacts",UPN2_023,7,148504781,G,C,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala738Gly/c.2213C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),9400,104,9573,"0,010863888",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,69,Tolerated,"17,79","14,43"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,7,148504781,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala738Asp/c.2213C>A|751|EZH2|protein_coding|CODING|ENST00000320356|20|T),6682,98,6849,"0,0143086582",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,11,Damaging,"19,38","15,63"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,7,148504781,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala738Asp/c.2213C>A|751|EZH2|protein_coding|CODING|ENST00000320356|20|T),7609,101,7786,"0,012972001",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,11,Damaging,"19,31","15,21"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,7,148504781,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala738Asp/c.2213C>A|751|EZH2|protein_coding|CODING|ENST00000320356|20|T),8059,111,8224,"0,0134970817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,11,Damaging,"18,57","14,72"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,7,148504781,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala738Asp/c.2213C>A|751|EZH2|protein_coding|CODING|ENST00000320356|20|T),5127,70,5239,"0,0133613285",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,11,Damaging,"17,77","14,63"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,7,148504781,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala738Asp/c.2213C>A|751|EZH2|protein_coding|CODING|ENST00000320356|20|T),8916,120,9123,"0,0131535679",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,11,Damaging,"19,27","14,3"
"low bq, bad alignment, low freq, many artifacts",UPN2_058,7,148504781,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala738Asp/c.2213C>A|751|EZH2|protein_coding|CODING|ENST00000320356|20|T),8988,94,9186,"0,0102329632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,11,Damaging,"18,52","14,51"
"low bq, bad alignment, many samples",UPN2_089,7,148504782,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala738Ser/c.2212G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),937,35,973,"0,035971223",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,42",Neutral,95,Tolerated,"19,97",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,7,148504782,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala738Ser/c.2212G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2548,28,2587,"0,0108233475",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,42",Neutral,95,Tolerated,"22,66","14,64"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_082,7,148504782,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala738Ser/c.2212G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1286,22,1315,"0,016730038",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,42",Neutral,95,Tolerated,"22,36",14
"low bq, bad alignment, many samples",UPN2_094,7,148504782,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala738Ser/c.2212G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),718,21,740,"0,0283783784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,42",Neutral,95,Tolerated,"19,1",14
"low bq, bad alignment, many samples",UPN2_096,7,148504782,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala738Ser/c.2212G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),650,31,681,"0,0455212922",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,42",Neutral,95,Tolerated,"19,46",14
"low bq, bad alignment, many samples",UPN2_097,7,148504782,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala738Ser/c.2212G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),723,25,749,"0,0333778371",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,42",Neutral,95,Tolerated,"19,27",14
"low bq, bad alignment, many samples",UPN2_100,7,148504782,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala738Ser/c.2212G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),899,40,940,"0,0425531915",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,42",Neutral,95,Tolerated,"20,16",14
"low bq, bad alignment, many samples",UPN2_101,7,148504782,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala738Ser/c.2212G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),649,24,674,"0,0356083086",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,42",Neutral,95,Tolerated,"19,42",14
"low bq, bad alignment, many samples",UPN2_102,7,148504782,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala738Ser/c.2212G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),791,33,825,"0,04",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,42",Neutral,95,Tolerated,"19,74",14
"low bq, bad alignment, many samples",UPN2_103,7,148504782,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala738Ser/c.2212G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),755,22,778,"0,028277635",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,42",Neutral,95,Tolerated,"19,4",15
"low bq, bad alignment, many samples",UPN2_104,7,148504782,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala738Ser/c.2212G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),645,20,665,"0,030075188",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,42",Neutral,95,Tolerated,19,14
"low bq, bad alignment, many samples",UPN2_105,7,148504782,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala738Ser/c.2212G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),792,40,833,"0,0480192077",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,42",Neutral,95,Tolerated,"18,88","14,18"
"low bq, bad alignment, many samples",UPN2_107,7,148504782,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala738Ser/c.2212G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),715,23,738,"0,0311653117",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,42",Neutral,95,Tolerated,"19,1",14
"low bq, bad alignment, many samples",UPN2_109,7,148504782,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala738Ser/c.2212G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),843,24,870,"0,0275862069",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,42",Neutral,95,Tolerated,"19,53",14
"low bq, bad alignment",UPN2_111,7,148504782,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala738Ser/c.2212G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),783,23,806,"0,0285359801",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,42",Neutral,95,Tolerated,"19,02",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_014,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8349,136,8509,"0,0159830767",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"26,17","17,15"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_015,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11633,204,11861,"0,0171992243",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"26,17","16,14"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_016,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5919,101,6033,"0,0167412564",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"25,23","15,44"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_017,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3270,57,3337,"0,0170812107",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"25,39","15,02"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_018,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5936,112,6072,"0,0184453228",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"25,15","16,23"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_019,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7717,134,7868,"0,0170310117",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"26,26","16,63"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_020,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3664,79,3747,"0,0210835335",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"23,78","16,47"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_021,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6002,117,6130,"0,01908646",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"23,64","15,68"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_022,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8635,172,8834,"0,0194702287",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"24,81","15,37"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_023,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9375,158,9572,"0,0165064772",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"25,67","14,96"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_024,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3054,51,3114,"0,0163776493",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"25,39","17,06"
"low bq, bad alignment, many samples",UPN2_025,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10627,241,10890,"0,0221303949",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"24,42","15,99"
"low bq, bad alignment, many samples",UPN2_026,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8183,217,8420,"0,0257719715",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"23,55","15,13"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_027,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11155,207,11391,"0,0181722412",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"24,73","16,07"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8470,155,8650,"0,0179190751",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,25,"15,81"
"low bq, bad alignment, many samples",UPN2_028,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8875,206,9099,"0,0226398505",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"24,46","14,88"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_043,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6585,120,6735,"0,0178173719",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"25,82","17,02"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_044,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1155,21,1183,"0,0177514793",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"25,94","16,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_029,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7837,136,7988,"0,0170255383",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"25,4","15,13"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_030,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8364,182,8565,"0,0212492703",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"24,46","15,75"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_031,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5556,93,5660,"0,0164310954",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"26,27","15,61"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4958,98,5075,"0,0193103448",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"24,99","15,38"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_032,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3406,55,3466,"0,0158684362",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"26,2","17,24"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10641,234,10905,"0,0214580468",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"25,18","15,7"
"low bq, bad alignment, many samples",UPN2_033,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5845,145,6007,"0,0241385051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"24,36","15,7"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_034,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1897,35,1939,"0,0180505415",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"25,03",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9883,220,10131,"0,0217155266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"25,4","16,49"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_048,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4064,71,4144,"0,0171332046",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"25,37","15,93"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_035,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11829,194,12043,"0,016108943",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"26,03","15,58"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_036,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13356,245,13633,"0,0179710995",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"25,64","15,93"
"low bq, low freq, many artifacts, many samples",UPN2_049,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6748,69,6846,"0,0100788782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"27,94","15,64"
"low bq, low freq, many artifacts, many samples",UPN2_050,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7671,90,7784,"0,0115621788",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"27,98","17,89"
"low bq, bad alignment, many samples",UPN2_037,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9163,207,9390,"0,0220447284",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"24,29","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_051,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8104,88,8216,"0,0107108082",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"27,12","17,24"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5125,84,5236,"0,0160427807",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"25,97","16,51"
"low bq, bad alignment, many samples",UPN2_038,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13245,305,13573,"0,0224710823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"24,49","15,2"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_039,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),18083,364,18493,"0,0196831233",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"25,7","16,11"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8648,127,8794,"0,0144416648",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"26,1","17,76"
"low bq, low freq, many artifacts, many samples",UPN2_054,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8983,114,9122,"0,0124972594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"27,85","18,03"
"low bq, low freq, many artifacts, many samples",UPN2_007,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11753,146,11920,"0,0122483221",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"28,07","15,9"
"low bq, low freq, many artifacts, many samples",UPN2_008,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13154,194,13368,"0,0145122681",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"27,38","16,41"
"low bq, low freq, many artifacts, many samples",UPN2_009,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10865,186,11072,"0,0167991329",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"27,31","16,12"
"low bq, low freq, many artifacts, many samples",UPN2_010,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10694,156,10873,"0,0143474662",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"28,15","16,27"
"low bq, low freq, many artifacts, many samples",UPN2_011,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10580,136,10742,"0,0126605846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"28,25","16,17"
"low bq, low freq, many artifacts, many samples",UPN2_055,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9150,126,9304,"0,0135425623",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"27,21","16,67"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2549,34,2586,"0,0131477185",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"26,97","14,65"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8365,138,8535,"0,016168717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"26,04","16,59"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_058,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8997,165,9180,"0,0179738562",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"26,24","16,29"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_012,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3311,49,3369,"0,0145443752",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"26,77","15,16"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_040,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8079,173,8269,"0,0209215141",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"25,38","15,15"
"low bq, low freq, many artifacts",UPN2_013,7,148504784,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp737Val/c.2210A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2480,41,2529,"0,0162119415",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,78",Deleterious,1,Damaging,"27,39","15,07"
"low bq, bad alignment",UPN2_111,7,148504785,C,A,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp737Tyr/c.2209G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),781,22,804,"0,0273631841",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,74",Deleterious,0,Damaging,"20,62",14
"low bq, bad alignment",UPN2_041,7,148504785,C,T,missense_variant(MODERATE|MISSENSE|Gat/Aat|p.Asp737Asn/c.2209G>A|751|EZH2|protein_coding|CODING|ENST00000320356|20|T),1209,33,1243,"0,0265486726",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,46",Neutral,1,Damaging,"23,08","20,7"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,7,148504787,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala736Asp/c.2207C>A|751|EZH2|protein_coding|CODING|ENST00000320356|20|T),7652,87,7779,"0,0111839568",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,77",Neutral,7,Damaging,"22,74","15,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,7,148504787,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala736Asp/c.2207C>A|751|EZH2|protein_coding|CODING|ENST00000320356|20|T),8626,106,8789,"0,0120605302",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,77",Neutral,7,Damaging,"20,25","14,7"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,7,148504787,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala736Asp/c.2207C>A|751|EZH2|protein_coding|CODING|ENST00000320356|20|T),2534,33,2583,"0,012775842",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,77",Neutral,7,Damaging,"20,87","19,67"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_001,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4237,49,4296,"0,011405959",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"23,63",14
"low bq, bad alignment, many samples",UPN2_089,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),868,98,968,"0,1012396694",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"18,24",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8445,159,8635,"0,0184134337",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"20,83","14,47"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_043,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6578,122,6723,"0,0181466607",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"21,2","14,25"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_044,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1158,22,1182,"0,0186125212",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"21,4",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4973,89,5068,"0,0175611681",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"20,64",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10665,187,10886,"0,0171780268",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"20,98","14,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9942,160,10117,"0,0158149649",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"21,07",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_048,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4051,81,4138,"0,0195746738",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"21,07",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_006,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5514,65,5586,"0,0116362334",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"23,55","14,75"
"low bq, bad alignment, many samples",UPN2_049,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6665,161,6838,"0,0235448962",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"21,98","14,25"
"low bq, bad alignment, many samples",UPN2_050,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7568,183,7773,"0,0235430336",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"21,93","14,12"
"low bq, bad alignment, many samples",UPN2_051,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8007,190,8211,"0,0231396907",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"21,37","14,09"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5108,114,5231,"0,0217931562",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"20,97","14,16"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8579,186,8785,"0,021172453",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"20,73","14,62"
"low bq, bad alignment, many samples",UPN2_054,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8869,212,9112,"0,0232660228",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"21,84","14,33"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_011,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10600,115,10736,"0,0107116244",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"23,52","14,42"
"low bq, bad alignment, many samples",UPN2_055,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9050,227,9297,"0,0244164784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"21,53","14,23"
"low bq, bad alignment, many samples",UPN2_056,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2514,61,2582,"0,0236250968",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"20,99","14,3"
"low bq, bad alignment, many samples",UPN2_090,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),375,48,424,"0,1132075472",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"18,26",14
"low bq, bad alignment, many samples",UPN2_057,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8309,192,8525,"0,0225219941",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"21,38","14,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_058,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8975,177,9171,"0,0192999673",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"21,41","14,4"
"low bq, bad alignment, many samples",UPN2_059,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),473,27,501,"0,0538922156",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"21,22","14,81"
"low bq, bad alignment, many samples",UPN2_060,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),679,34,715,"0,0475524476",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"21,8",14
"low bq, bad alignment, many samples",UPN2_091,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),402,26,429,"0,0606060606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"18,11",14
"low bq, bad alignment, many samples",UPN2_092,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),292,22,315,"0,0698412698",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"18,3",14
"low bq, bad alignment, many samples",UPN2_093,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),534,82,616,"0,1331168831",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"18,43",14
"low bq, bad alignment, many samples",UPN2_063,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),640,28,668,"0,0419161677",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"21,47",14
"low bq, bad alignment, many samples",UPN2_064,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),754,40,794,"0,0503778338",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"21,96",14
"low bq, bad alignment, many samples",UPN2_067,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),442,26,469,"0,0554371002",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"22,04",14
"low bq, bad alignment, many samples",UPN2_068,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),609,33,643,"0,0513219285",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"21,74",14
"low bq, bad alignment, many samples",UPN2_069,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1000,28,1030,"0,027184466",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"22,07",14
"low bq, bad alignment, many samples",UPN2_070,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),612,25,637,"0,0392464678",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"21,71",14
"low bq, bad alignment, many samples",UPN2_072,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),909,49,958,"0,0511482255",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"21,7","14,27"
"low bq, bad alignment, many samples",UPN2_078,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),742,38,781,"0,0486555698",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"22,18",14
"low bq, bad alignment, many samples",UPN2_079,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),407,24,432,"0,0555555556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"22,56","14,92"
"low bq, bad alignment, many samples",UPN2_080,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),702,32,737,"0,0434192673",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"21,71",14
"low bq, bad alignment, many samples",UPN2_081,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),894,39,935,"0,0417112299",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"22,32","14,79"
"low bq, bad alignment, many samples",UPN2_082,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1259,52,1312,"0,0396341463",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"21,34",14
"low bq, bad alignment, many samples",UPN2_083,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),686,30,717,"0,0418410042",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"22,32",14
"low bq, bad alignment, many samples",UPN2_088,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),818,49,869,"0,0563866513",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"21,88","14,37"
"low bq, bad alignment, many samples",UPN2_094,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),636,102,739,"0,1380243572",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"17,79",14
"low bq, bad alignment, many samples",UPN2_095,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),705,82,788,"0,1040609137",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"18,32",14
"low bq, bad alignment, many samples",UPN2_096,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),587,90,681,"0,1321585903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"18,08",14
"low bq, bad alignment, many samples",UPN2_097,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),652,94,746,"0,1260053619",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"17,86","14,14"
"low bq, bad alignment, many samples",UPN2_098,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),799,102,902,"0,1130820399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"18,73","14,13"
"low bq, bad alignment, many samples",UPN2_100,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),842,98,940,"0,1042553191",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"18,5",14
"low bq, bad alignment, many samples",UPN2_101,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),609,60,669,"0,0896860987",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"17,89",14
"low bq, bad alignment, many samples",UPN2_102,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),726,96,824,"0,1165048544",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"18,16",14
"low bq, bad alignment, many samples",UPN2_103,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),692,83,776,"0,1069587629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"18,04",14
"low bq, bad alignment, many samples",UPN2_104,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),576,88,664,"0,1325301205",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"17,82",14
"low bq, bad alignment, many samples",UPN2_105,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),728,103,831,"0,1239470517",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"17,92","14,07"
"low bq, bad alignment, many samples",UPN2_106,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),506,57,565,"0,1008849558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"18,56","14,32"
"low bq, bad alignment, many samples",UPN2_107,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),670,65,735,"0,0884353741",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"18,12",14
"low bq, bad alignment, many samples",UPN2_108,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),804,77,882,"0,0873015873",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"18,41",14
"low bq, bad alignment, many samples",UPN2_109,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),773,93,867,"0,107266436",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"18,11","14,14"
"low bq, bad alignment, many samples",UPN2_110,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),408,43,451,"0,0953436807",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"17,61",14
"low bq, bad alignment",UPN2_111,7,148504788,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala736Ser/c.2206G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),713,88,802,"0,1097256858",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,05",Neutral,263,Tolerated,"18,12",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_041,7,148504789,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln735His/c.2205G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1221,20,1241,"0,0161160355",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,"0,03",Damaging,"22,82","14,9"
"low bq, bad alignment, many samples",UPN2_089,7,148504789,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln735His/c.2205G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),930,37,968,"0,0382231405",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,"0,03",Damaging,"19,92",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,7,148504789,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln735His/c.2205G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8465,152,8632,"0,0176088971",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,"0,03",Damaging,"22,87","14,43"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_043,7,148504789,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln735His/c.2205G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6638,69,6721,"0,0102663294",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,"0,03",Damaging,"23,32","14,52"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_044,7,148504789,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln735His/c.2205G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1159,20,1181,"0,016934801",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,"0,03",Damaging,"23,45","15,1"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,7,148504789,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln735His/c.2205G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4974,84,5067,"0,0165778567",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,"0,03",Damaging,"22,79","14,15"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,7,148504789,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln735His/c.2205G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10682,195,10884,"0,0179162073",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,"0,03",Damaging,"22,89","14,18"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,7,148504789,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln735His/c.2205G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9925,176,10114,"0,0174016215",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,"0,03",Damaging,"22,97","14,36"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_048,7,148504789,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln735His/c.2205G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4067,65,4135,"0,015719468",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,"0,03",Damaging,"23,02",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,7,148504789,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln735His/c.2205G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6714,105,6834,"0,0153643547",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,"0,03",Damaging,"24,13","14,5"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,7,148504789,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln735His/c.2205G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7636,121,7768,"0,015576725",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,"0,03",Damaging,"24,12","14,55"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,7,148504789,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln735His/c.2205G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8013,180,8205,"0,0219378428",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,"0,03",Damaging,"23,23","14,47"
"low bq, bad alignment, many samples",UPN2_052,7,148504789,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln735His/c.2205G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5054,161,5226,"0,030807501",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,"0,03",Damaging,"22,22","14,16"
"low bq, bad alignment, many samples",UPN2_053,7,148504789,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln735His/c.2205G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8490,292,8790,"0,0332195677",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,"0,03",Damaging,"22,36","14,27"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,7,148504789,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln735His/c.2205G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8969,130,9108,"0,0142731664",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,"0,03",Damaging,"23,98","14,33"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,7,148504789,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln735His/c.2205G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9082,191,9292,"0,0205553164",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,"0,03",Damaging,"23,26","14,35"
"low bq, bad alignment, many samples",UPN2_056,7,148504789,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln735His/c.2205G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2518,62,2582,"0,0240123935",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,"0,03",Damaging,"22,9","14,65"
"low bq, bad alignment, many samples",UPN2_090,7,148504789,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln735His/c.2205G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),401,22,423,"0,0520094563",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,"0,03",Damaging,"19,36",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,7,148504789,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln735His/c.2205G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8400,103,8518,"0,0120920404",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,"0,03",Damaging,"23,48","14,47"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_013,7,148504789,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln735His/c.2205G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2495,27,2528,"0,0106803797",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,"0,03",Damaging,"25,66","14,81"
"low bq, bad alignment, many samples",UPN2_091,7,148504789,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln735His/c.2205G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),391,37,429,"0,0862470862",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,"0,03",Damaging,"19,43",14
"low bq, bad alignment, many samples",UPN2_093,7,148504789,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln735His/c.2205G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),594,22,616,"0,0357142857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,"0,03",Damaging,"19,49",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_082,7,148504789,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln735His/c.2205G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1287,20,1309,"0,0152788388",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,"0,03",Damaging,"23,86","14,9"
"low bq, bad alignment, many samples",UPN2_094,7,148504789,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln735His/c.2205G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),704,34,739,"0,0460081191",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,"0,03",Damaging,"19,31",14
"low bq, bad alignment, many samples",UPN2_095,7,148504789,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln735His/c.2205G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),751,37,788,"0,0469543147",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,"0,03",Damaging,"19,58",14
"low bq, bad alignment, many samples",UPN2_096,7,148504789,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln735His/c.2205G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),642,37,681,"0,0543318649",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,"0,03",Damaging,"19,59",14
"low bq, bad alignment, many samples",UPN2_097,7,148504789,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln735His/c.2205G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),706,36,743,"0,0484522207",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,"0,03",Damaging,"19,46",14
"low bq, bad alignment, many samples",UPN2_098,7,148504789,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln735His/c.2205G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),865,36,901,"0,0399556049",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,"0,03",Damaging,"20,52",14
"low bq, bad alignment, many samples",UPN2_100,7,148504789,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln735His/c.2205G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),907,31,940,"0,0329787234",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,"0,03",Damaging,"20,03",14
"low bq, bad alignment, many samples",UPN2_101,7,148504789,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln735His/c.2205G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),633,33,667,"0,0494752624",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,"0,03",Damaging,"19,37",14
"low bq, bad alignment, many samples",UPN2_102,7,148504789,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln735His/c.2205G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),786,38,824,"0,0461165049",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,"0,03",Damaging,"19,31","14,18"
"low bq, bad alignment, many samples",UPN2_103,7,148504789,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln735His/c.2205G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),740,36,776,"0,0463917526",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,"0,03",Damaging,"19,4",14
"low bq, bad alignment, many samples",UPN2_104,7,148504789,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln735His/c.2205G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),617,47,664,"0,0707831325",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,"0,03",Damaging,"19,24","14,15"
"low bq, bad alignment, many samples",UPN2_105,7,148504789,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln735His/c.2205G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),793,37,831,"0,0445246691",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,"0,03",Damaging,"19,1","14,59"
"low bq, bad alignment, many samples",UPN2_106,7,148504789,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln735His/c.2205G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),532,32,565,"0,0566371681",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,"0,03",Damaging,"19,34","14,22"
"low bq, bad alignment, many samples",UPN2_107,7,148504789,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln735His/c.2205G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),695,38,733,"0,0518417462",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,"0,03",Damaging,"19,73",14
"low bq, bad alignment, many samples",UPN2_108,7,148504789,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln735His/c.2205G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),817,64,881,"0,0726447219",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,"0,03",Damaging,"19,45","14,11"
"low bq, bad alignment, many samples",UPN2_110,7,148504789,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln735His/c.2205G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),427,24,451,"0,0532150776",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,"0,03",Damaging,"18,9",14
"low bq, bad alignment",UPN2_111,7,148504789,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln735His/c.2205G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),758,44,802,"0,0548628429",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,"0,03",Damaging,"19,48",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_001,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4234,52,4295,"0,0121071013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"25,56","17,58"
"low bq, bad alignment, many samples",UPN2_014,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8282,188,8491,"0,0221410906",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"21,06","15,9"
"low bq, bad alignment, many samples",UPN2_015,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11408,404,11838,"0,0341273864",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"20,81","15,37"
"low bq, bad alignment, many samples",UPN2_016,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5816,194,6023,"0,0322098622",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"20,61","15,21"
"low bq, bad alignment, many samples",UPN2_017,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3210,105,3328,"0,0315504808",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"20,61","15,05"
"low bq, bad alignment, many samples",UPN2_018,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5847,206,6068,"0,0339485827",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"20,41","15,36"
"low bq, bad alignment, many samples",UPN2_019,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7581,253,7859,"0,0321923909",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"20,93","15,68"
"low bq, bad alignment, many samples",UPN2_020,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3617,117,3741,"0,0312750601",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"19,91","14,34"
"low bq, bad alignment, many samples",UPN2_021,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5869,230,6115,"0,0376124285",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"19,65","14,86"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_002,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4485,56,4549,"0,0123103979",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"25,42","17,95"
"low bq, bad alignment, many samples",UPN2_022,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8439,355,8812,"0,0402859737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"20,06",15
"low bq, bad alignment, many samples",UPN2_023,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9190,333,9552,"0,034861809",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"20,55","15,22"
"low bq, bad alignment, many samples",UPN2_041,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1188,47,1240,"0,0379032258",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"21,35","14,66"
"low bq, bad alignment, many samples",UPN2_024,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2986,114,3111,"0,0366441659",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"20,47","15,32"
"low bq, bad alignment, many samples",UPN2_025,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10421,425,10877,"0,0390732739",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"19,77","15,28"
"low bq, bad alignment, many samples",UPN2_026,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7946,432,8406,"0,051391863",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"19,29","14,98"
"low bq, bad alignment, many samples",UPN2_027,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10875,471,11371,"0,0414211591",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"19,86","15,1"
"low bq, bad alignment, many samples",UPN2_042,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8284,295,8621,"0,0342187681",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"21,39","15,51"
"low bq, bad alignment, many samples",UPN2_028,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8678,377,9083,"0,0415061103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"19,74","15,36"
"low bq, bad alignment, many samples",UPN2_043,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6499,189,6716,"0,028141751",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"21,9","15,21"
"low bq, bad alignment, many samples",UPN2_044,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1133,40,1178,"0,0339558574",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"21,56","14,98"
"low bq, bad alignment, many samples",UPN2_029,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7681,260,7972,"0,0326141495",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"20,33","15,3"
"low bq, bad alignment, many samples",UPN2_030,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8203,325,8553,"0,0379983631",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"19,6","15,33"
"low bq, bad alignment, many samples",UPN2_031,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5450,178,5648,"0,0315155807",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"21,03","15,17"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_005,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1392,21,1416,"0,0148305085",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"25,52","15,57"
"low bq, bad alignment, many samples",UPN2_045,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4887,159,5061,"0,0314167161",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"21,04","15,48"
"low bq, bad alignment, many samples",UPN2_032,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3341,113,3459,"0,0326684013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"20,76","16,47"
"low bq, bad alignment, many samples",UPN2_046,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10469,380,10872,"0,0349521707",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"21,25","15,24"
"low bq, bad alignment, many samples",UPN2_033,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5720,267,5997,"0,0445222611",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"19,69","14,78"
"low bq, bad alignment, many samples",UPN2_034,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1852,79,1936,"0,0408057851",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"20,07","15,11"
"low bq, bad alignment, many samples",UPN2_047,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9740,338,10109,"0,0334355525",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"21,52","15,47"
"low bq, bad alignment, many samples",UPN2_048,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3967,150,4130,"0,0363196126",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"21,41","15,09"
"low bq, bad alignment, many samples",UPN2_035,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11591,397,12021,"0,0330255386",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"20,75","15,4"
"low bq, bad alignment, many samples",UPN2_036,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13127,447,13606,"0,032853153",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"20,51","15,15"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_006,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5489,76,5585,"0,0136078782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"25,23","15,11"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6683,134,6830,"0,0196193265",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"23,96","15,92"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7578,160,7764,"0,0206079341",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"23,87","16,11"
"low bq, bad alignment, many samples",UPN2_037,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8919,429,9377,"0,0457502399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"19,57","15,1"
"low bq, bad alignment, many samples",UPN2_051,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7985,188,8201,"0,0229240337",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"23,3","15,46"
"low bq, bad alignment, many samples",UPN2_052,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5064,146,5225,"0,0279425837",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"22,2","15,32"
"low bq, bad alignment, many samples",UPN2_038,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),12878,627,13548,"0,0462798937",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"19,88","15,04"
"low bq, bad alignment, many samples",UPN2_039,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),17756,647,18454,"0,0350601496",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"20,49","14,81"
"low bq, bad alignment, many samples",UPN2_053,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8551,215,8789,"0,0244623962",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"22,24","15,56"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8900,166,9101,"0,0182397539",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"23,78","15,75"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_007,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11630,251,11910,"0,0210747271",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"23,93","15,43"
"low bq, bad alignment, many samples",UPN2_008,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13024,297,13351,"0,0222455247",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"23,32","14,95"
"low bq, bad alignment, many samples",UPN2_009,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10759,272,11060,"0,0245931284",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"23,19","14,8"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_010,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10645,185,10861,"0,0170334223",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"23,95","15,72"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_011,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10496,213,10730,"0,0198508854",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"24,06","15,73"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9059,195,9286,"0,0209993539",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"23,48","15,5"
"low bq, bad alignment, many samples",UPN2_056,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2510,57,2580,"0,0220930233",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"22,7","16,95"
"low bq, bad alignment, many samples",UPN2_057,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8240,233,8513,"0,0273699049",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"21,95","15,39"
"low bq, bad alignment, many samples",UPN2_058,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8871,253,9159,"0,027623103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"22,1","15,55"
"low bq, bad alignment, many samples",UPN2_012,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3264,96,3368,"0,0285035629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"22,7","15,17"
"low bq, bad alignment, many samples",UPN2_040,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7924,298,8249,"0,036125591",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"20,46","14,74"
"low bq, bad alignment, many samples",UPN2_013,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2449,78,2528,"0,0308544304",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"23,78","15,64"
"low bq, bad alignment, low freq, many artifacts",UPN2_082,7,148504790,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln735Leu/c.2204A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1281,21,1309,"0,0160427807",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,87,Tolerated,"22,57","16,1"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_014,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),8329,102,8488,"0,0120169651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"15,93",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_015,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),11540,201,11830,"0,0169907016",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"16,31","14,03"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_016,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),5904,75,6022,"0,0124543341",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"16,1",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_019,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),7691,105,7858,"0,0133621787",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"15,94","14,25"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_021,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),6003,69,6111,"0,0112911144",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"15,74",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_022,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),8616,126,8811,"0,0143003064",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"15,99",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_023,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),9311,166,9550,"0,017382199",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,16,"14,08"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_024,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),3037,52,3111,"0,0167148827",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"16,28","14,13"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_025,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),10613,176,10871,"0,0161898629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"15,71","14,07"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_026,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),8222,129,8405,"0,0153480071",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"15,74",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_027,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),11102,174,11365,"0,0153101628",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"15,87",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_089,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),942,20,967,"0,0206825233",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"15,41",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),8371,134,8613,"0,0155578776",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"16,61","14,05"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_028,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),8868,151,9080,"0,0166299559",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"15,68",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_043,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),6519,125,6713,"0,0186205869",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"16,53","14,06"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_029,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),7757,147,7967,"0,0184511108",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"15,85","14,05"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_030,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),8366,126,8553,"0,0147316731",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"15,39","14,06"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_031,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),5524,86,5643,"0,0152401205",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"16,33","14,41"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),4887,103,5056,"0,0203718354",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"16,37",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_032,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),3374,58,3458,"0,016772701",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"16,35",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),10545,201,10864,"0,0185014728",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"16,67","14,06"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_033,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),5880,87,5997,"0,0145072536",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"15,72","14,31"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_034,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),1888,30,1935,"0,015503876",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"15,94",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),9787,182,10100,"0,018019802",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"16,74",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_048,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),4010,77,4125,"0,0186666667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"16,64",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_035,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),11745,180,12015,"0,0149812734",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"16,05","14,24"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_036,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),13264,236,13598,"0,0173554935",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"16,01",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),6639,84,6827,"0,0123040867",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"17,62","14,26"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),7583,79,7760,"0,0101804124",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"17,53",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_037,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),9149,153,9373,"0,0163234823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"15,68",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),8020,88,8201,"0,0107303987",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"17,34",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),5108,59,5222,"0,0112983531",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"16,99","14,22"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_038,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),13215,206,13540,"0,0152141802",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"15,83",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_039,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),17991,331,18440,"0,0179501085",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"16,05","14,08"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),8582,115,8788,"0,0130860264",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"17,1",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),8867,108,9098,"0,0118707408",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"17,53",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_008,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),13111,134,13350,"0,0100374532",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"17,7",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_009,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),10837,119,11060,"0,0107594937",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"17,59","14,11"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),9064,114,9281,"0,0122831591",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"17,37",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),2523,31,2579,"0,0120201629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"17,16","14,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),8267,142,8509,"0,0166882125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"16,86","14,05"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_058,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),8924,138,9154,"0,0150753769",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"16,94","14,13"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_040,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),8051,142,8242,"0,017228828",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"16,11",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_013,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),2475,29,2527,"0,0114760586",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"17,79",14
"low bq, bad alignment, many samples",UPN2_069,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),992,31,1027,"0,0301850049",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"18,02",14
"low bq, bad alignment, many samples",UPN2_078,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),756,20,781,"0,0256081946",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"18,49",14
"low bq, bad alignment, many samples",UPN2_080,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),708,21,736,"0,0285326087",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"17,73",14
"low bq, bad alignment, many samples",UPN2_081,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),900,28,935,"0,0299465241",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"18,84",14
"low bq, bad alignment",UPN2_082,7,148504791,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln735Glu/c.2203C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),1260,37,1308,"0,0282874618",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,89,Tolerated,"17,71","14,35"
"low bq, bad alignment",UPN2_082,7,148504792,G,C,missense_variant(MODERATE|MISSENSE|agC/agG|p.Ser734Arg/c.2202C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),1263,29,1308,"0,0221712538",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,46",Neutral,23,Damaging,"18,11",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,7,148504792,G,T,missense_variant(MODERATE|MISSENSE|agC/agA|p.Ser734Arg/c.2202C>A|751|EZH2|protein_coding|CODING|ENST00000320356|20|T),8386,108,8609,"0,012545011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,46",Neutral,23,Damaging,"16,79","14,33"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,7,148504792,G,T,missense_variant(MODERATE|MISSENSE|agC/agA|p.Ser734Arg/c.2202C>A|751|EZH2|protein_coding|CODING|ENST00000320356|20|T),4911,69,5054,"0,0136525524",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,46",Neutral,23,Damaging,"16,63","14,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,7,148504792,G,T,missense_variant(MODERATE|MISSENSE|agC/agA|p.Ser734Arg/c.2202C>A|751|EZH2|protein_coding|CODING|ENST00000320356|20|T),9837,111,10097,"0,0109933644",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,46",Neutral,23,Damaging,"16,94","14,23"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,7,148504792,G,T,missense_variant(MODERATE|MISSENSE|agC/agA|p.Ser734Arg/c.2202C>A|751|EZH2|protein_coding|CODING|ENST00000320356|20|T),6677,82,6826,"0,0120128919",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,46",Neutral,23,Damaging,"18,05","14,55"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,7,148504792,G,T,missense_variant(MODERATE|MISSENSE|agC/agA|p.Ser734Arg/c.2202C>A|751|EZH2|protein_coding|CODING|ENST00000320356|20|T),7583,101,7758,"0,0130188193",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,46",Neutral,23,Damaging,"17,86","14,53"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,7,148504792,G,T,missense_variant(MODERATE|MISSENSE|agC/agA|p.Ser734Arg/c.2202C>A|751|EZH2|protein_coding|CODING|ENST00000320356|20|T),8010,118,8197,"0,0143955106",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,46",Neutral,23,Damaging,"17,39","14,77"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,7,148504792,G,T,missense_variant(MODERATE|MISSENSE|agC/agA|p.Ser734Arg/c.2202C>A|751|EZH2|protein_coding|CODING|ENST00000320356|20|T),5078,93,5219,"0,0178195057",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,46",Neutral,23,Damaging,"16,9",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,7,148504792,G,T,missense_variant(MODERATE|MISSENSE|agC/agA|p.Ser734Arg/c.2202C>A|751|EZH2|protein_coding|CODING|ENST00000320356|20|T),8530,168,8788,"0,0191169777",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,46",Neutral,23,Damaging,"16,9","14,49"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,7,148504792,G,T,missense_variant(MODERATE|MISSENSE|agC/agA|p.Ser734Arg/c.2202C>A|751|EZH2|protein_coding|CODING|ENST00000320356|20|T),8886,121,9095,"0,0133040132",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,46",Neutral,23,Damaging,"17,93","14,24"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,7,148504792,G,T,missense_variant(MODERATE|MISSENSE|agC/agA|p.Ser734Arg/c.2202C>A|751|EZH2|protein_coding|CODING|ENST00000320356|20|T),9051,132,9280,"0,0142241379",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,46",Neutral,23,Damaging,"17,59","14,67"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,7,148504792,G,T,missense_variant(MODERATE|MISSENSE|agC/agA|p.Ser734Arg/c.2202C>A|751|EZH2|protein_coding|CODING|ENST00000320356|20|T),2509,44,2579,"0,0170608763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,46",Neutral,23,Damaging,"17,15","14,5"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,7,148504792,G,T,missense_variant(MODERATE|MISSENSE|agC/agA|p.Ser734Arg/c.2202C>A|751|EZH2|protein_coding|CODING|ENST00000320356|20|T),8286,106,8503,"0,0124661884",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,46",Neutral,23,Damaging,"17,38","15,01"
"low bq, bad alignment, low freq, many artifacts",UPN2_058,7,148504792,G,T,missense_variant(MODERATE|MISSENSE|agC/agA|p.Ser734Arg/c.2202C>A|751|EZH2|protein_coding|CODING|ENST00000320356|20|T),8940,101,9149,"0,0110394579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,46",Neutral,23,Damaging,"17,31","14,77"
"low bq, bad alignment, many samples",UPN2_089,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),880,85,966,"0,0879917184",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"18,11","14,08"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8463,116,8610,"0,0134727062",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"21,82","14,22"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4957,76,5054,"0,015037594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"21,86","14,75"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10697,154,10859,"0,0141817847",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"21,96","14,61"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9924,154,10095,"0,0152550768",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"22,04","14,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_048,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4050,67,4129,"0,0162266893",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"21,85","14,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6707,99,6825,"0,0145054945",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"23,24","14,81"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7617,107,7757,"0,0137939925",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"22,84","14,29"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8033,139,8197,"0,0169574234",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"22,26","14,8"
"low bq, bad alignment, many samples",UPN2_052,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5056,150,5219,"0,0287411381",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"21,38","14,19"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8585,184,8793,"0,0209257364",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"21,39","14,18"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8950,119,9096,"0,0130826737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"22,93","14,6"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9091,169,9277,"0,018217096",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"22,4","14,13"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2522,49,2581,"0,0189848896",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"21,98","14,14"
"low bq, bad alignment, many samples",UPN2_090,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),373,50,424,"0,1179245283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"18,2",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8403,91,8504,"0,0107008467",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"22,39","14,43"
"low bq, bad alignment, many samples",UPN2_060,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),694,22,716,"0,030726257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"21,88",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_013,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2497,26,2528,"0,0102848101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"25,33",14
"low bq, bad alignment, many samples",UPN2_091,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),372,54,427,"0,1264637002",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"18,22",14
"low bq, bad alignment, many samples",UPN2_092,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),284,27,314,"0,0859872611",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"17,99",14
"low bq, bad alignment, many samples",UPN2_093,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),555,60,616,"0,0974025974",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"18,05",14
"low bq, bad alignment, many samples",UPN2_063,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),638,25,666,"0,0375375375",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"22,45",14
"low bq, bad alignment, many samples",UPN2_064,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),769,21,795,"0,0264150943",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"21,67",14
"low bq, bad alignment, many samples",UPN2_069,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),996,33,1029,"0,0320699708",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"22,61",14
"low bq, bad alignment, many samples",UPN2_070,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),613,23,636,"0,036163522",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"22,62","14,78"
"low bq, bad alignment, many samples",UPN2_072,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),932,22,956,"0,0230125523",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"22,24","14,59"
"low bq, bad alignment, many samples",UPN2_075,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),644,20,666,"0,03003003",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"22,06","14,35"
"low bq, bad alignment, many samples",UPN2_080,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),704,30,736,"0,0407608696",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"22,17","14,23"
"low bq, bad alignment, many samples",UPN2_081,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),906,29,937,"0,0309498399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"22,55",14
"low bq, bad alignment, many samples",UPN2_082,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1273,41,1317,"0,0311313591",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"21,58","14,32"
"low bq, bad alignment, many samples",UPN2_088,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),829,38,868,"0,0437788018",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"22,25","14,18"
"low bq, bad alignment, many samples",UPN2_094,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),660,77,739,"0,1041948579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"17,99","14,09"
"low bq, bad alignment, many samples",UPN2_095,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),700,86,788,"0,1091370558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"18,37","14,08"
"low bq, bad alignment, many samples",UPN2_096,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),616,65,681,"0,0954478708",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"17,82","14,2"
"low bq, bad alignment, many samples",UPN2_097,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),652,87,739,"0,1177266576",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"17,95","14,08"
"low bq, bad alignment, many samples",UPN2_098,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),820,80,901,"0,0887902331",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"18,84",14
"low bq, bad alignment, many samples",UPN2_100,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),832,106,940,"0,1127659574",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"18,5",14
"low bq, bad alignment, many samples",UPN2_101,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),610,55,666,"0,0825825826",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"17,75",14
"low bq, bad alignment, many samples",UPN2_102,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),746,77,825,"0,0933333333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"18,27",14
"low bq, bad alignment, many samples",UPN2_103,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),700,77,777,"0,0990990991",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"18,14","14,32"
"low bq, bad alignment, many samples",UPN2_104,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),584,79,663,"0,1191553544",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"17,83","14,09"
"low bq, bad alignment, many samples",UPN2_105,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),728,97,830,"0,1168674699",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"18,05",14
"low bq, bad alignment, many samples",UPN2_106,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),501,63,566,"0,1113074205",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"18,54",14
"low bq, bad alignment, many samples",UPN2_107,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),672,60,732,"0,0819672131",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"18,56",14
"low bq, bad alignment, many samples",UPN2_108,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),793,87,882,"0,0986394558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"18,16",14
"low bq, bad alignment, many samples",UPN2_109,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),783,82,866,"0,0946882217",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"18,28",14
"low bq, bad alignment, many samples",UPN2_110,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),406,43,450,"0,0955555556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"18,18","14,16"
"low bq, bad alignment",UPN2_111,7,148504793,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser734Ile/c.2201G>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),714,87,802,"0,108478803",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,9,Damaging,"18,26",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_001,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4235,46,4293,"0,0107151176",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"25,34","15,98"
"low bq, bad alignment, many samples",UPN2_014,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8195,263,8485,"0,0309958751",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"19,99","15,34"
"low bq, bad alignment, many samples",UPN2_015,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11385,393,11823,"0,0332402943",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"20,19","15,11"
"low bq, bad alignment, many samples",UPN2_016,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5827,164,6022,"0,0272334773",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"19,86","14,97"
"low bq, bad alignment, many samples",UPN2_017,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3226,87,3328,"0,0261418269",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"19,93","14,44"
"low bq, bad alignment, many samples",UPN2_018,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5909,144,6072,"0,023715415",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"19,69","14,85"
"low bq, bad alignment, many samples",UPN2_019,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7611,209,7854,"0,0266106443",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"20,03","15,46"
"low bq, bad alignment, many samples",UPN2_020,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3611,115,3744,"0,030715812",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"19,64","15,02"
"low bq, bad alignment, many samples",UPN2_021,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5908,178,6113,"0,0291182725",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"19,39","14,85"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_002,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4488,46,4556,"0,0100965759",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"25,69","16,2"
"low bq, bad alignment, many samples",UPN2_022,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8494,284,8817,"0,0322105024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"19,68","14,79"
"low bq, bad alignment, many samples",UPN2_023,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9137,364,9549,"0,0381191748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"19,77","15,3"
"low bq, bad alignment, many samples",UPN2_041,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1185,37,1241,"0,0298146656",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"21,42","14,95"
"low bq, bad alignment, many samples",UPN2_024,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2998,102,3108,"0,0328185328",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"19,95","16,09"
"low bq, bad alignment, many samples",UPN2_025,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10454,385,10878,"0,0353925354",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"19,2","14,66"
"low bq, bad alignment, many samples",UPN2_026,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8099,274,8409,"0,032584136",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"19,36","14,66"
"low bq, bad alignment, many samples",UPN2_027,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10935,396,11370,"0,034828496",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"19,45","14,74"
"low bq, bad alignment, many samples",UPN2_042,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8298,281,8614,"0,0326213141",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"21,3","15,08"
"low bq, bad alignment, many samples",UPN2_028,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8733,330,9097,"0,0362756953",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"19,26","14,67"
"low bq, bad alignment, many samples",UPN2_043,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6488,190,6708,"0,0283243888",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"21,18","14,66"
"low bq, bad alignment, many samples",UPN2_044,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1145,39,1187,"0,0328559393",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"21,32","14,33"
"low bq, bad alignment, many samples",UPN2_029,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7662,281,7994,"0,0351513635",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"19,48","14,69"
"low bq, bad alignment, many samples",UPN2_030,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8233,305,8576,"0,0355643657",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"18,97","14,88"
"low bq, bad alignment, many samples",UPN2_031,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5430,184,5639,"0,0326298989",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"20,26","14,74"
"low bq, bad alignment, many samples",UPN2_045,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4882,150,5056,"0,0296677215",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"20,99","14,96"
"low bq, bad alignment, many samples",UPN2_032,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3315,132,3458,"0,038172354",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"20,25","14,67"
"low bq, bad alignment, many samples",UPN2_046,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10492,310,10862,"0,0285398637",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"21,21","15,05"
"low bq, bad alignment, many samples",UPN2_033,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5754,214,6005,"0,0356369692",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"19,43","14,7"
"low bq, bad alignment, many samples",UPN2_034,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1862,66,1932,"0,0341614907",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"19,73","16,23"
"low bq, bad alignment, many samples",UPN2_047,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9749,295,10100,"0,0292079208",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"21,28","14,96"
"low bq, bad alignment, many samples",UPN2_048,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4019,94,4135,"0,022732769",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"21,31","14,93"
"low bq, bad alignment, many samples",UPN2_035,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11540,436,12011,"0,0363000583",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,20,15
"low bq, bad alignment, many samples",UPN2_036,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13071,459,13590,"0,0337748344",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"19,76","14,84"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_006,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5483,72,5591,"0,0128778394",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"25,39","15,85"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6645,143,6823,"0,0209585226",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"23,39","16,03"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7567,148,7757,"0,0190795411",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"23,36","15,89"
"low bq, bad alignment, many samples",UPN2_037,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9019,313,9390,"0,0333333333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"19,31","14,65"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8007,145,8198,"0,0176872408",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"23,16","16,04"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5097,99,5224,"0,0189509954",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"22,58","15,67"
"low bq, bad alignment, many samples",UPN2_038,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),12950,540,13536,"0,039893617",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"19,41","14,77"
"low bq, bad alignment, many samples",UPN2_039,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),17636,714,18428,"0,0387453875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"19,8","14,73"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8604,148,8804,"0,0168105407",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"22,62","15,79"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8874,185,9096,"0,0203386104",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"23,16","15,69"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_007,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11632,243,11911,"0,0204013097",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"23,88","14,89"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_008,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),13048,278,13368,"0,0207959306",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"23,59","15,15"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_009,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10818,218,11078,"0,0196786424",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"23,56","15,08"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_010,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10588,229,10856,"0,0210943257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"23,79","15,57"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_011,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10465,220,10751,"0,0204632127",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"24,01","15,3"
"low bq, bad alignment, many samples",UPN2_055,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9041,207,9275,"0,0223180593",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"23,1","15,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2534,41,2585,"0,015860735",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"22,93","16,12"
"low bq, bad alignment, many samples",UPN2_057,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8220,254,8501,"0,0298788378",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"21,48","14,78"
"low bq, bad alignment, many samples",UPN2_058,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8852,255,9146,"0,0278810409",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"21,57","14,93"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_012,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3300,63,3379,"0,0186445694",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"23,29","15,41"
"low bq, bad alignment, many samples",UPN2_040,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7914,291,8239,"0,0353198204",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"19,84","15,06"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_013,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2473,51,2533,"0,0201342282",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"23,6","14,96"
"low bq, bad alignment",UPN2_082,7,148504794,T,A,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser734Cys/c.2200A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1286,41,1333,"0,0307576894",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,89",Deleterious,19,Damaging,"21,17","14,44"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_015,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),11603,164,11830,"0,01386306",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"17,45",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_017,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),3289,37,3336,"0,0110911271",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"17,08",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_019,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),7725,87,7854,"0,0110771581",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"17,18","14,08"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_020,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),3690,46,3761,"0,0122307897",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"16,53","14,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_021,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),6030,64,6132,"0,0104370515",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"16,36","14,52"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_022,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),8696,101,8841,"0,0114240471",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"16,92","14,47"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_023,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),9376,128,9553,"0,0133989323",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"17,12",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_041,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),1213,21,1244,"0,0168810289",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"17,64",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_024,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),3064,37,3119,"0,0118627765",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"17,4","14,35"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_025,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),10666,156,10905,"0,0143053645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"16,5","14,04"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_026,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),8259,113,8435,"0,0133965619",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"16,37","14,06"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_027,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),11173,152,11388,"0,0133473832",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"16,73","14,13"
"low bq, bad alignment, many samples",UPN2_089,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),934,24,966,"0,0248447205",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"15,63","14,29"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),8390,142,8615,"0,0164828787",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"17,52","14,15"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_028,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),8931,119,9108,"0,013065437",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"16,51",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_043,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),6565,94,6710,"0,0140089419",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"17,9","14,48"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_044,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),1166,20,1199,"0,0166805671",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"18,15",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_029,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),7893,92,8029,"0,0114584631",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"16,93","14,61"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_030,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),8463,105,8614,"0,012189459",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"16,32","14,24"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_031,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),5545,66,5639,"0,0117042029",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"17,46","14,11"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),4949,71,5066,"0,014015002",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"17,43",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_032,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),3413,39,3457,"0,0112814579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"17,52","14,64"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),10600,164,10871,"0,0150860086",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"17,62",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_033,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),5933,66,6026,"0,010952539",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"16,61","14,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_034,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),1913,28,1950,"0,0143589744",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"16,99",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),9858,167,10107,"0,0165232017",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"17,74","14,08"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_048,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),4047,67,4147,"0,0161562575",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"17,81","14,1"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_035,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),11799,165,12011,"0,0137374074",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"17,34","14,15"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_036,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),13344,189,13589,"0,0139083082",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"17,18","14,2"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),6683,84,6823,"0,0123113",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"19,3","17,04"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),7582,94,7756,"0,0121196493",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"19,25","14,19"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_037,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),9270,124,9439,"0,0131369849",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"16,47",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),5103,63,5228,"0,0120504973",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"17,78",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_038,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),13309,190,13562,"0,0140097331",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"16,72","14,24"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_039,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),18106,253,18437,"0,013722406",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"17,16","14,1"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),9093,94,9278,"0,0101314939",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"18,64","14,81"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),2541,27,2591,"0,010420687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"18,28",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),8306,118,8504,"0,0138758231",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"18,25","14,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_058,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),8916,147,9145,"0,0160743576",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"18,34","14,69"
"low bq, bad alignment, many samples",UPN2_060,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),690,21,717,"0,0292887029",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"18,73",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_040,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),8075,128,8243,"0,0155283271",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"17,1","14,2"
"low bq, bad alignment, many samples",UPN2_064,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),767,24,796,"0,0301507538",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"18,29",14
"low bq, bad alignment, many samples",UPN2_068,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),616,26,643,"0,0404354588",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"18,17",14
"low bq, bad alignment, many samples",UPN2_069,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),997,28,1030,"0,027184466",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"18,84",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),932,21,957,"0,0219435737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"18,37","15,05"
"low bq, bad alignment, many samples",UPN2_075,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),637,27,667,"0,0404797601",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"18,36",14
"low bq, bad alignment, many samples",UPN2_078,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),760,20,782,"0,0255754476",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"18,62","14,35"
"low bq, bad alignment, many samples",UPN2_081,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),893,37,936,"0,0395299145",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"18,88","14,19"
"low bq, bad alignment, many samples",UPN2_082,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),1325,54,1390,"0,0388489209",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"18,65","14,33"
"low bq, bad alignment, many samples",UPN2_083,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),690,23,715,"0,0321678322",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"18,86",14
"low bq, bad alignment, many samples",UPN2_088,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),842,22,870,"0,0252873563",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"18,21",14
"low bq, bad alignment, many samples",UPN2_097,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),709,23,742,"0,0309973046",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"15,59",14
"low bq, bad alignment, many samples",UPN2_108,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),859,24,889,"0,0269966254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,16,14
"low bq, bad alignment",UPN2_109,7,148504795,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr733*/c.2199C>G|751|EZH2|protein_coding|CODING|ENST00000320356|20|C),841,23,868,"0,0264976959",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"15,67",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_001,7,148504796,T,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4205,86,4302,"0,019990702",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"24,26","14,99"
"low bq, bad alignment, many samples",UPN2_014,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8119,362,8491,"0,0426333765",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"19,2","14,47"
"low bq, bad alignment, many samples",UPN2_016,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5751,304,6064,"0,0501319261",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"18,76","14,64"
"low bq, bad alignment, many samples",UPN2_017,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3178,170,3355,"0,0506706408",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"18,99","14,38"
"low bq, bad alignment, many samples",UPN2_018,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5766,323,6108,"0,0528814669",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"18,59","14,6"
"low bq, bad alignment, many samples",UPN2_019,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7477,367,7860,"0,046692112",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"19,2","14,55"
"low bq, bad alignment, many samples",UPN2_020,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3560,237,3805,"0,0622864652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"18,1","14,81"
"low bq, bad alignment, many samples",UPN2_002,7,148504796,T,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4482,120,4611,"0,0260247235",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"24,03","14,59"
"low bq, bad alignment, many samples",UPN2_022,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8345,526,8891,"0,0591609493",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"18,48","14,55"
"low bq, bad alignment, many samples",UPN2_041,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1176,69,1248,"0,0552884615",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"20,72","14,75"
"low bq, bad alignment, many samples",UPN2_024,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2927,205,3136,"0,065369898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"18,84","14,58"
"low bq, bad alignment, many samples",UPN2_089,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),942,29,973,"0,0298047276",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"18,34",14
"low bq, bad alignment, many samples",UPN2_042,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8174,440,8642,"0,0509141402",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"20,2","14,5"
"low bq, bad alignment, many samples",UPN2_043,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6395,302,6713,"0,044987338",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"20,77","14,25"
"low bq, bad alignment, many samples",UPN2_044,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1138,60,1203,"0,0498753117",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"20,87","14,22"
"low bq, bad alignment, many samples",UPN2_031,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5336,293,5639,"0,0519595673",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"19,32","14,55"
"low bq, bad alignment, many samples",UPN2_005,7,148504796,T,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1406,32,1441,"0,0222068008",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"24,09","16,5"
"low bq, bad alignment, many samples",UPN2_045,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),4827,238,5079,"0,046859618",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"20,22","14,33"
"low bq, bad alignment, many samples",UPN2_046,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10335,565,10924,"0,0517209813",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"20,25","14,33"
"low bq, bad alignment, many samples",UPN2_033,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5711,355,6089,"0,0583018558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"18,11","14,34"
"low bq, bad alignment, many samples",UPN2_034,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1843,114,1967,"0,0579562786",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"18,58","14,4"
"low bq, bad alignment, many samples",UPN2_047,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),9614,501,10142,"0,0493985407",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"20,49","14,41"
"low bq, bad alignment, many samples",UPN2_048,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3951,215,4172,"0,0515340364",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"20,51","14,57"
"low bq, bad alignment, many samples",UPN2_035,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11383,616,12028,"0,0512138344",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"18,83","14,7"
"low bq, bad alignment, many samples",UPN2_006,7,148504796,T,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5475,134,5623,"0,0238306954",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"23,73","14,81"
"low bq, bad alignment, many samples",UPN2_049,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),6611,211,6839,"0,0308524638",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"23,04","14,71"
"low bq, bad alignment, many samples",UPN2_050,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7479,244,7756,"0,0314595152",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"22,88","15,03"
"low bq, bad alignment, many samples",UPN2_051,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),7956,256,8237,"0,0310792764",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"22,2","14,36"
"low bq, bad alignment, many samples",UPN2_052,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),5035,216,5263,"0,0410412312",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"21,27","14,65"
"low bq, bad alignment, many samples",UPN2_039,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),17352,1065,18456,"0,0577048114",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"18,83","14,65"
"low bq, bad alignment, many samples",UPN2_053,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8485,370,8873,"0,0416995379",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"21,4","14,38"
"low bq, bad alignment, many samples",UPN2_054,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8805,266,9099,"0,0292339818",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"22,75","14,52"
"low bq, bad alignment, many samples",UPN2_007,7,148504796,T,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),11503,425,11946,"0,0355767621",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"22,44","14,26"
"low bq, bad alignment, many samples",UPN2_008,7,148504796,T,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),12891,544,13463,"0,0404070415",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"21,78","14,53"
"low bq, bad alignment, many samples",UPN2_009,7,148504796,T,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10686,465,11167,"0,041640548",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"21,7","14,49"
"low bq, bad alignment, many samples",UPN2_010,7,148504796,T,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10459,406,10887,"0,0372921833",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"22,54","14,52"
"low bq, bad alignment, many samples",UPN2_011,7,148504796,T,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),10409,349,10787,"0,0323537592",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"22,77","14,45"
"low bq, bad alignment, many samples",UPN2_055,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8961,314,9299,"0,0337670717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"22,3","14,82"
"low bq, bad alignment, many samples",UPN2_056,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2503,102,2610,"0,0390804598",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"21,9","14,39"
"low bq, bad alignment, many samples",UPN2_057,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8078,408,8506,"0,0479661415",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"21,07","14,59"
"low bq, bad alignment, many samples",UPN2_058,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),8738,399,9159,"0,0435637078",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"21,04","14,3"
"low bq, bad alignment, many samples",UPN2_012,7,148504796,T,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),3300,150,3452,"0,0434530707",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"21,42","14,51"
"low bq, bad alignment, many samples",UPN2_013,7,148504796,T,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),2436,116,2559,"0,0453302071",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"21,57","14,44"
"low bq, bad alignment, many samples",UPN2_064,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),779,20,799,"0,0250312891",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"22,47",14
"low bq, bad alignment, many samples",UPN2_068,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),622,22,644,"0,0341614907",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"22,74",14
"low bq, bad alignment, many samples",UPN2_069,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),999,30,1032,"0,0290697674",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"22,74","14,87"
"low bq, bad alignment, many samples",UPN2_072,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),938,25,965,"0,0259067358",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"22,83",14
"low bq, bad alignment, many samples",UPN2_075,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),648,20,670,"0,0298507463",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"22,42","14,9"
"low bq, bad alignment, many samples",UPN2_078,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),765,20,787,"0,0254129606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"22,71",14
"low bq, bad alignment, many samples",UPN2_080,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),714,28,742,"0,0377358491",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"22,13",14
"low bq, bad alignment, many samples",UPN2_081,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),911,31,942,"0,0329087049",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"22,69",14
"low bq, bad alignment, many samples",UPN2_082,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),1439,52,1498,"0,0347129506",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"21,66","14,35"
"low bq, bad alignment, many samples",UPN2_095,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),768,20,789,"0,0253485425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"17,88",14
"low bq, bad alignment, many samples",UPN2_097,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),723,20,743,"0,0269179004",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"17,65",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_100,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),923,20,944,"0,0211864407",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"19,73","14,65"
"low bq, bad alignment, many samples",UPN2_108,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),869,24,894,"0,0268456376",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"18,06",14
"low bq, bad alignment, many samples",UPN2_109,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),844,25,872,"0,0286697248",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"17,77","14,52"
"low bq, bad alignment",UPN2_111,7,148504796,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr733Phe/c.2198A>T|751|EZH2|protein_coding|CODING|ENST00000320356|20|A),784,21,806,"0,0260545906",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,1,Damaging,"18,19",14
"low freq, many artifacts",UPN2_040,7,148506170,C,CA,frameshift_variant(HIGH||ttt/tttT|p.Asp730fs/c.2187dupT|751|EZH2|protein_coding|CODING|ENST00000320356|19|CA),10694,109,10724,"0,0101641179",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,7",NA
"low freq, many artifacts, many samples",UPN2_013,7,148506170,CA,C,frameshift_variant(HIGH||ttt/|p.Phe729fs/c.2187delT|751|EZH2|protein_coding|CODING|ENST00000320356|19|C),5092,53,5158,"0,0102753005",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,67",NA
"low freq, many artifacts, many samples",UPN2_080,7,148506170,CA,C,frameshift_variant(HIGH||ttt/|p.Phe729fs/c.2187delT|751|EZH2|protein_coding|CODING|ENST00000320356|19|C),6078,65,6166,"0,0105416802",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,65",NA
"inspected, bad alignment, many artifacts",UPN2_044,7,148506172,A,G,missense_variant(MODERATE|MISSENSE|tTt/tCt|p.Phe729Ser/c.2186T>C|751|EZH2|protein_coding|CODING|ENST00000320356|19|G),2898,39,2940,"0,0132653061",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,95",Deleterious,0,Damaging,"35,59",34
"inspected, bad alignment, many artifacts",UPN2_040,7,148506200,C,A,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala720Ser/c.2158G>T|751|EZH2|protein_coding|CODING|ENST00000320356|19|A),10497,194,10715,"0,0181054596",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,2",Neutral,"0,407",Tolerated,"34,6","34,26"
"inspected, bad alignment, many artifacts",UPN2_093,7,148506227,G,A,missense_variant(MODERATE|MISSENSE|Cac/Tac|p.His711Tyr/c.2131C>T|751|EZH2|protein_coding|CODING|ENST00000320356|19|A),4079,42,4123,"0,0101867572",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,22",Deleterious,0,Damaging,"34,78","35,81"
"low bq, low freq, many artifacts, many samples",UPN2_062,7,148506238,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val707Gly/c.2120T>G|751|EZH2|protein_coding|CODING|ENST00000320356|19|C),4379,47,4447,"0,0105689229",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,09",Deleterious,0,Damaging,"29,12","15,09"
"low bq, low freq, many artifacts",UPN2_064,7,148506238,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val707Gly/c.2120T>G|751|EZH2|protein_coding|CODING|ENST00000320356|19|C),6635,75,6750,"0,0111111111",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,09",Deleterious,0,Damaging,"29,28","14,44"
"inspected, bad alignment, many artifacts",UPN2_056,7,148506417,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn699Asp/c.2095A>G|751|EZH2|protein_coding|CODING|ENST00000320356|18|C),2375,31,2421,"0,0128046262",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"33,7","34,87"
"low bq, low freq, many artifacts",UPN2_043,7,148506431,T,A,missense_variant(MODERATE|MISSENSE|cAt/cTt|p.His694Leu/c.2081A>T|751|EZH2|protein_coding|CODING|ENST00000320356|18|A),13209,136,13412,"0,010140173",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-9,62",Deleterious,0,Damaging,"33,56","19,4"
"low bq, low freq, many artifacts, many samples",UPN2_043,7,148506435,T,A,missense_variant(MODERATE|MISSENSE|Aat/Tat|p.Asn693Tyr/c.2077A>T|751|EZH2|protein_coding|CODING|ENST00000320356|18|A),13246,142,13457,"0,010552129",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,99",Deleterious,0,Damaging,"34,12","20,51"
"low bq, low freq, many artifacts, many samples",UPN2_052,7,148506435,T,A,missense_variant(MODERATE|MISSENSE|Aat/Tat|p.Asn693Tyr/c.2077A>T|751|EZH2|protein_coding|CODING|ENST00000320356|18|A),14065,146,14282,"0,0102226579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,99",Deleterious,0,Damaging,"34,04","20,4"
"low bq, low freq, many artifacts, many samples",UPN2_053,7,148506435,T,A,missense_variant(MODERATE|MISSENSE|Aat/Tat|p.Asn693Tyr/c.2077A>T|751|EZH2|protein_coding|CODING|ENST00000320356|18|A),19718,200,19999,"0,0100005",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,99",Deleterious,0,Damaging,34,"20,94"
"low bq, low freq, many artifacts, many samples",UPN2_001,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),14122,264,14406,"0,0183256976",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"32,17","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_014,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),22812,513,23372,"0,0219493411",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,73","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_015,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),32028,668,32789,"0,020372686",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,68","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_016,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),15510,340,15897,"0,0213876832",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,76","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_017,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),10280,224,10540,"0,0212523719",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,72","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_018,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),15784,346,16176,"0,0213897132",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,68","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_019,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),19191,383,19621,"0,0195199021",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,7","14,3"
"low bq, many samples",UPN2_020,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),14098,321,14461,"0,022197635",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,7","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_021,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),17656,374,18074,"0,0206927078",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,67","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_002,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),19757,361,20190,"0,0178801387",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"32,17","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_003,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),3819,46,3871,"0,0118832343",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"32,31","14,28"
"low bq, many samples",UPN2_022,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),23839,564,24468,"0,023050515",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,72","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_023,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),25708,579,26350,"0,0219734345",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,79","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_024,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),11992,270,12288,"0,0219726563",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,83","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_025,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),26888,570,27526,"0,0207076945",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,86","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_026,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),27822,551,28437,"0,0193761649",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,8","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_004,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),1767,28,1796,"0,0155902004",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"32,25","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_027,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),32779,738,33584,"0,0219747499",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,72","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_089,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),20417,331,20797,"0,0159157571",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,78","15,34"
"low bq, many samples",UPN2_042,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),35024,1045,36246,"0,0288307675",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,99","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_028,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),24181,482,24729,"0,0194912855",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,72","14,67"
"low bq, many samples",UPN2_043,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),25811,815,26737,"0,0304821035",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,92","15,05"
"low bq, many samples",UPN2_044,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),4805,144,4962,"0,0290205562",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,01","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_029,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),23410,473,23948,"0,0197511274",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,74","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_030,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),18949,416,19411,"0,0214311473",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,68","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_031,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),16574,343,16943,"0,0202443487",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,74","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_005,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),5735,97,5854,"0,0165698668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"32,03","14,58"
"low bq, many samples",UPN2_045,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),28664,843,29655,"0,0284269095",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,93","15,08"
"low bq, many samples",UPN2_032,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),9036,238,9294,"0,0256079191",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,74","14,76"
"low bq, many samples",UPN2_046,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),35246,1067,36433,"0,0292866357",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,95","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_033,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),18650,412,19112,"0,0215571369",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,68","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_034,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),7097,131,7248,"0,0180739514",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,74","14,64"
"low bq, many samples",UPN2_047,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),40466,1256,41948,"0,0299418327",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,94","15,13"
"low bq, many samples",UPN2_048,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),11145,326,11511,"0,0283207367",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,11","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_035,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),32267,718,33047,"0,0217266318",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,77","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_036,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),35920,790,36841,"0,0214435004",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,7","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_006,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),22346,391,22787,"0,0171589064",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"31,96","14,95"
"low bq, many samples",UPN2_049,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),23946,849,24872,"0,03413477",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,71","14,82"
"low bq, many samples",UPN2_050,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),28456,805,29397,"0,0273837466",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,92",15
"low bq, low freq, many artifacts, many samples",UPN2_037,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),34940,708,35750,"0,0198041958",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,73","14,75"
"low bq, many samples",UPN2_051,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),28642,780,29544,"0,0264012998",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,94","15,29"
"low bq, many samples",UPN2_052,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),27397,780,28314,"0,0275482094",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,99","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_038,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),43458,963,44524,"0,0216287845",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,64","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_039,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),47981,979,49091,"0,0199425557",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,7","14,69"
"low bq, many samples",UPN2_053,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),38484,1132,39764,"0,028467961",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,98","14,93"
"low bq, many samples",UPN2_054,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),23852,725,24680,"0,029376013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,30,"15,01"
"low bq, low freq, many artifacts, many samples",UPN2_007,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),42763,800,43627,"0,0183372682",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"32,02","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_008,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),56978,1029,58129,"0,0177020076",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"32,03","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_009,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),43977,851,44930,"0,0189405742",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"31,91","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_010,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),34336,641,35052,"0,0182871163",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"32,01","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_011,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),41806,830,42756,"0,0194124801",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"32,06","14,95"
"low bq, many samples",UPN2_055,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),35862,1086,37129,"0,0292493738",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,95",15
"low bq, many samples",UPN2_056,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),4698,152,4862,"0,0312628548",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,95","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_090,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),14760,295,15087,"0,0195532578",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,67","15,96"
"low bq, many samples",UPN2_057,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),34458,1039,35617,"0,0291714631",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,91","15,27"
"low bq, many samples",UPN2_058,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),30969,966,32041,"0,0301488718",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,97","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_059,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),10053,191,10282,"0,0185761525",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,21","15,76"
"low bq, low freq, many artifacts, many samples",UPN2_012,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),14320,282,14651,"0,0192478329",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"31,99","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_060,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),24751,478,25334,"0,0188679245",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,21","15,89"
"low bq, low freq, many artifacts, many samples",UPN2_040,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),29196,648,29954,"0,0216331709",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,69","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_013,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),11694,213,11930,"0,0178541492",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"31,97","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_091,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),14962,247,15245,"0,0162020335",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,59","15,86"
"low bq, low freq, many artifacts, many samples",UPN2_092,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),9018,173,9219,"0,0187655928",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,77","16,03"
"low bq, low freq, many artifacts, many samples",UPN2_093,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),10409,196,10636,"0,0184279804",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,58","16,4"
"low bq, low freq, many artifacts, many samples",UPN2_061,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),20413,396,20879,"0,0189664256",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,16","16,06"
"low bq, low freq, many artifacts, many samples",UPN2_062,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),21223,374,21662,"0,0172652571",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,14","15,69"
"low bq, low freq, many artifacts, many samples",UPN2_063,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),20599,400,21058,"0,0189951562",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,22","15,95"
"low bq, low freq, many artifacts, many samples",UPN2_064,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),18698,401,19154,"0,0209355748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,16","16,19"
"low bq, low freq, many artifacts, many samples",UPN2_065,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),18912,362,19358,"0,018700279",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,06","15,85"
"low bq, low freq, many artifacts, many samples",UPN2_066,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),29265,590,29935,"0,0197093703",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,2","16,42"
"low bq, low freq, many artifacts, many samples",UPN2_067,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),29832,583,30498,"0,0191160076",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,2","15,83"
"low bq, low freq, many artifacts, many samples",UPN2_068,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),24350,418,24839,"0,0168283747",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,21","15,93"
"low bq, low freq, many artifacts, many samples",UPN2_069,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),29060,552,29697,"0,0185877361",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,11","15,71"
"low bq, low freq, many artifacts, many samples",UPN2_070,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),18828,316,19199,"0,0164591906",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,09","15,72"
"low bq, low freq, many artifacts, many samples",UPN2_071,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),18342,334,18722,"0,0178399744",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,1","15,76"
"low bq, many samples",UPN2_072,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),10701,250,10987,"0,022754164",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,11","15,81"
"low bq, low freq, many artifacts, many samples",UPN2_073,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),16758,371,17176,"0,0215999068",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,06","16,2"
"low bq, low freq, many artifacts, many samples",UPN2_074,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),15009,271,15334,"0,0176731446",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,16","15,99"
"low bq, low freq, many artifacts, many samples",UPN2_075,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),28755,587,29426,"0,019948345",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,22","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_076,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),22552,395,23022,"0,0171575015",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,23","15,82"
"low bq, low freq, many artifacts, many samples",UPN2_077,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),27798,540,28467,"0,0189693329",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,04","15,68"
"low bq, low freq, many artifacts, many samples",UPN2_078,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),24534,435,25087,"0,017339658",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,22","15,85"
"low bq, low freq, many artifacts, many samples",UPN2_079,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),16440,303,16798,"0,0180378617",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,16","15,94"
"low bq, low freq, many artifacts, many samples",UPN2_080,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),24641,517,25273,"0,0204566138",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,12","15,74"
"low bq, low freq, many artifacts, many samples",UPN2_081,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),12195,249,12501,"0,0199184065",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,15","15,62"
"low bq, low freq, many artifacts, many samples",UPN2_082,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),30692,682,31490,"0,0216576691",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,14","15,72"
"low bq, low freq, many artifacts, many samples",UPN2_083,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),29633,505,30251,"0,016693663",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,24","15,94"
"low bq, low freq, many artifacts, many samples",UPN2_084,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),29717,544,30380,"0,0179065174",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,25","15,7"
"low bq, low freq, many artifacts, many samples",UPN2_085,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),21466,422,21965,"0,0192123833",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,04","16,04"
"low bq, low freq, many artifacts, many samples",UPN2_086,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),12706,216,12961,"0,0166653808",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,21","15,88"
"low bq, low freq, many artifacts, many samples",UPN2_087,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),30671,623,31415,"0,0198312908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,12","15,55"
"low bq, low freq, many artifacts, many samples",UPN2_088,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),24443,482,25018,"0,0192661284",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,09","15,62"
"low bq, low freq, many artifacts, many samples",UPN2_094,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),19474,358,19878,"0,0180098601",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,72","15,84"
"low bq, low freq, many artifacts, many samples",UPN2_095,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),18408,334,18792,"0,0177735206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,68","15,88"
"low bq, low freq, many artifacts, many samples",UPN2_096,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),20933,389,21384,"0,018191171",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,71","15,75"
"low bq, low freq, many artifacts, many samples",UPN2_097,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),19082,343,19464,"0,017622277",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,68","16,45"
"low bq, low freq, many artifacts, many samples",UPN2_098,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),18002,335,18388,"0,0182184033",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,61","16,06"
"low bq, low freq, many artifacts, many samples",UPN2_099,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),10451,192,10673,"0,0179893188",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,63","16,5"
"low bq, low freq, many artifacts, many samples",UPN2_100,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),15976,261,16287,"0,0160250507",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,7","15,85"
"low bq, low freq, many artifacts, many samples",UPN2_101,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),17576,281,17904,"0,0156948168",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,83","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_102,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),18856,312,19228,"0,0162263366",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,74","16,13"
"low bq, low freq, many artifacts, many samples",UPN2_103,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),18533,261,18827,"0,013863069",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,69","15,77"
"low bq, low freq, many artifacts, many samples",UPN2_104,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),21588,359,21988,"0,0163270875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,75","15,7"
"low bq, low freq, many artifacts, many samples",UPN2_105,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),17855,351,18241,"0,0192423661",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,67","15,99"
"low bq, low freq, many artifacts, many samples",UPN2_106,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),23296,424,23774,"0,0178346092",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,67","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_107,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),32611,639,33323,"0,0191759445",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,72","15,94"
"low bq, low freq, many artifacts, many samples",UPN2_108,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),24944,432,25433,"0,0169858058",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,73","15,55"
"low bq, low freq, many artifacts, many samples",UPN2_109,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),25808,445,26319,"0,0169079372",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,72","15,71"
"low bq, low freq, many artifacts, many samples",UPN2_110,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),27185,490,27737,"0,0176659336",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,66","15,9"
"low bq, low freq, many artifacts",UPN2_111,7,148506437,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala692Glu/c.2075C>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),25276,403,25728,"0,0156638682",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,71","15,72"
"inspected, bad alignment, many artifacts",UPN2_056,7,148506468,C,T,missense_variant(MODERATE|MISSENSE|Gca/Aca|p.Ala682Thr/c.2044G>A|751|EZH2|protein_coding|CODING|ENST00000320356|18|T),4796,63,4882,"0,0129045473",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,0,Damaging,"33,54","34,33"
"inspected, bad alignment, many artifacts",UPN2_041,7,148507424,C,T,splice_donor_variant+intron_variant(HIGH|||c.2029+1G>A|751|EZH2|protein_coding|CODING|ENST00000320356|17|T),4318,75,4400,"0,0170454545",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,,,,,"35,52","35,2"
"Not in 2nd Illumina, many artifacts, low freq",UPN2_006,7,148507428,T,C,missense_variant(MODERATE|MISSENSE|Aat/Gat|p.Asn676Asp/c.2026A>G|751|EZH2|protein_coding|CODING|ENST00000320356|17|C),4844,152,5015,"0,0303090728",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,32",Deleterious,"0,077",Tolerated,"34,73","35,24"
"inspected, bad alignment, many artifacts",UPN2_044,7,148507449,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser669Arg/c.2005A>C|751|EZH2|protein_coding|CODING|ENST00000320356|17|G),3664,64,3797,"0,0168554122",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,"0,001",Damaging,"35,1",35
"Not in 2nd Illumina, many artifacts, low freq",UPN2_004,7,148507502,A,G,missense_variant(MODERATE|MISSENSE|aTt/aCt|p.Ile651Thr/c.1952T>C|751|EZH2|protein_coding|CODING|ENST00000320356|17|G),3330,36,3371,"0,0106793236",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"34,71","35,42"
"inspected, bad alignment, many artifacts",UPN2_048,7,148508719,C,T,missense_variant(MODERATE|MISSENSE|Gag/Aag|p.Glu649Lys/c.1945G>A|751|EZH2|protein_coding|CODING|ENST00000320356|16|T),3357,46,3406,"0,0135055784",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-3,64",Deleterious,0,Damaging,"35,32","34,96"
"inspected, bad alignment, many artifacts",UPN2_044,7,148508721,C,T,missense_variant(MODERATE|MISSENSE|gGa/gAa|p.Gly648Glu/c.1943G>A|751|EZH2|protein_coding|CODING|ENST00000320356|16|T),2305,28,2340,"0,011965812",0,0,0,0,1,0,0,1,2,NO,NO,COSM3259628,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-7,29",Deleterious,0,Damaging,"35,34","34,43"
"inspected, bad alignment, many artifacts",UPN2_041,7,148508734,A,G,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser644Pro/c.1930T>C|751|EZH2|protein_coding|CODING|ENST00000320356|16|G),880,30,911,"0,0329308452",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,"0,001",Damaging,"35,53","35,13"
"Not in 2nd Illumina, many artifacts, low freq",UPN2_006,7,148508743,C,T,missense_variant(MODERATE|MISSENSE|Gaa/Aaa|p.Glu641Lys/c.1921G>A|751|EZH2|protein_coding|CODING|ENST00000320356|16|T),5093,90,5192,"0,0173343606",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,61",Deleterious,"0,002",Damaging,"35,24","35,32"
"low bq, many samples",UPN2_001,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),5642,131,5796,"0,0226017943",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,30,"14,79"
"low bq, many samples",UPN2_014,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),13085,353,13515,"0,0261191269",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,03","14,81"
"low bq, many samples",UPN2_015,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),20447,646,21175,"0,0305076741",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"28,98","14,83"
"low bq, many samples",UPN2_016,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),10328,249,10632,"0,0234198646",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,1","15,27"
"low bq, many samples",UPN2_017,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),5792,179,5999,"0,0298383064",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,02","14,72"
"low bq, many samples",UPN2_018,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),11578,294,11916,"0,024672709",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,29,"14,41"
"low bq, many samples",UPN2_019,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),12504,408,12961,"0,0314790525",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,07","14,79"
"low bq, many samples",UPN2_020,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),6689,189,6900,"0,0273913043",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,1","14,53"
"low bq, many samples",UPN2_021,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),10633,277,10944,"0,0253106725",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,19","14,91"
"low bq, many samples",UPN2_002,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),7385,201,7616,"0,0263918067",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,9","14,81"
"low bq, many samples",UPN2_003,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),1483,36,1521,"0,0236686391",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,68","14,56"
"low bq, many samples",UPN2_022,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),13137,395,13607,"0,0290291762",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,08","14,67"
"low bq, many samples",UPN2_023,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),13433,416,13899,"0,0299302108",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"28,93","14,78"
"low bq, many samples",UPN2_041,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),1720,57,1786,"0,0319148936",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,6","15,11"
"low bq, many samples",UPN2_024,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),5992,174,6181,"0,0281507847",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,25","14,54"
"low bq, many samples",UPN2_025,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),17948,457,18484,"0,0247240857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,18","14,34"
"low bq, many samples",UPN2_026,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),15484,487,16022,"0,0303957059",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,01","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_004,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),1805,28,1845,"0,0151761518",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"30,1","14,25"
"low bq, many samples",UPN2_027,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),16297,515,16890,"0,030491415",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,29,"14,6"
"low bq, low freq, many artifacts, many samples",UPN2_089,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),9000,119,9141,"0,0130182693",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,56","14,47"
"low bq, many samples",UPN2_042,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),19565,661,20304,"0,0325551615",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,53","15,09"
"low bq, many samples",UPN2_028,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),12788,436,13285,"0,0328189688",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"28,82","14,49"
"low bq, many samples",UPN2_043,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),12907,405,13373,"0,0302849024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,78","14,8"
"low bq, many samples",UPN2_044,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),4403,148,4559,"0,0324632595",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,41","14,95"
"low bq, many samples",UPN2_029,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),9989,306,10334,"0,0296109928",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,12","14,44"
"low bq, many samples",UPN2_030,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),15234,469,15748,"0,0297815596",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,17","14,99"
"low bq, many samples",UPN2_031,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),10592,293,10937,"0,0267897961",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,29","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_005,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),2265,50,2328,"0,0214776632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,8","15,02"
"low bq, many samples",UPN2_045,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),10908,357,11323,"0,0315287468",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,62","14,98"
"low bq, many samples",UPN2_032,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),4203,107,4334,"0,0246885095",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,24","14,52"
"low bq, many samples",UPN2_046,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),18663,620,19348,"0,0320446558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,54","14,98"
"low bq, many samples",UPN2_033,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),11040,303,11391,"0,0265999473",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,27","15,09"
"low bq, many samples",UPN2_034,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),3486,104,3605,"0,0288488211",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"28,97","15,05"
"low bq, many samples",UPN2_047,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),20075,670,20814,"0,0321898722",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,58","15,08"
"low bq, many samples",UPN2_048,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),6457,197,6674,"0,0295175307",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,6","14,3"
"low bq, many samples",UPN2_035,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),16373,418,16870,"0,0247777119",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,18","14,74"
"low bq, many samples",UPN2_036,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),13083,360,13533,"0,0266016404",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,09","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_006,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),9974,212,10218,"0,0207477001",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"30,04","14,75"
"low bq, many samples",UPN2_049,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),11678,377,12107,"0,0311390105",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,62","14,8"
"low bq, many samples",UPN2_050,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),13672,470,14187,"0,0331289208",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,58",15
"low bq, many samples",UPN2_037,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),20375,643,21120,"0,0304450758",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"28,9","15,05"
"low bq, many samples",UPN2_051,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),18137,541,18739,"0,0288702706",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,71","14,86"
"low bq, many samples",UPN2_052,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),11414,421,11863,"0,0354884936",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,43","14,89"
"low bq, many samples",UPN2_038,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),25500,797,26385,"0,0302065568",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,01","14,76"
"low bq, many samples",UPN2_039,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),23815,757,24688,"0,0306626701",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"28,95","14,53"
"low bq, many samples",UPN2_053,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),20705,736,21533,"0,0341800957",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,58","14,7"
"low bq, many samples",UPN2_054,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),12530,494,13065,"0,0378109453",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,5","15,13"
"low bq, many samples",UPN2_007,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),16334,373,16749,"0,0222699863",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"30,06","14,89"
"low bq, many samples",UPN2_008,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),25152,573,25834,"0,0221800728",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,86","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_009,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),20995,435,21530,"0,020204366",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,92","14,49"
"low bq, many samples",UPN2_010,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),16033,399,16508,"0,0241700993",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,87","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_011,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),15413,311,15788,"0,0196985052",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,99","14,67"
"low bq, many samples",UPN2_055,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),18769,629,19464,"0,0323160707",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,55","15,07"
"low bq, many samples",UPN2_056,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),5637,176,5846,"0,0301060554",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,34","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_090,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),5173,69,5262,"0,0131128848",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,27","14,29"
"low bq, many samples",UPN2_057,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),12495,448,13004,"0,0344509382",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,65","14,8"
"low bq, many samples",UPN2_058,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),10888,323,11274,"0,0286499911",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,72","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_059,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),37743,439,38410,"0,0114293153",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,93","16,4"
"low bq, many samples",UPN2_012,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),8075,186,8309,"0,0223853653",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"30,08","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_060,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),22333,292,22724,"0,0128498504",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,86","16,6"
"low bq, many samples",UPN2_040,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),11714,328,12105,"0,0270962412",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,05","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_013,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),4576,99,4690,"0,021108742",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,98","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_091,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),4660,70,4739,"0,0147710487",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,64","14,19"
"low bq, low freq, many artifacts, many samples",UPN2_092,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),2307,30,2340,"0,0128205128",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,43",14
"low bq, low freq, many artifacts, many samples",UPN2_093,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),3210,38,3255,"0,0116743472",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,32","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_061,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),23315,315,23782,"0,0132453116",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,74","15,61"
"low bq, low freq, many artifacts, many samples",UPN2_062,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),16616,201,16895,"0,0118970109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,7","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_063,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),20179,237,20508,"0,0115564658",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,93","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_065,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),32365,368,32900,"0,0111854103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"30,01","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_066,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),49431,573,50224,"0,0114088882",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,92","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_067,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),48561,530,49312,"0,010747891",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"30,12",15
"low bq, low freq, many artifacts, many samples",UPN2_068,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),30524,381,31051,"0,0122701362",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,94","15,37"
"low bq, low freq, many artifacts, many samples",UPN2_069,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),30016,365,30491,"0,0119707455",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,97","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_070,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),20338,245,20699,"0,0118363206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,86","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_071,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),7835,98,7962,"0,0123084652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,83","16,08"
"low bq, low freq, many artifacts, many samples",UPN2_072,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),13179,136,13372,"0,0101705055",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,95","15,97"
"low bq, low freq, many artifacts, many samples",UPN2_074,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),22215,265,22593,"0,0117292967",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,76","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_076,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),21427,260,21804,"0,0119244175",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,81","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_077,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),31709,361,32229,"0,0112010922",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,72","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_078,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),17855,188,18116,"0,0103775668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,79","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_079,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),13373,142,13572,"0,0104627174",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,93","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_081,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),27042,292,27475,"0,0106278435",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"30,01","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_083,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),29448,346,29922,"0,0115633982",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,77","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_084,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),34929,381,35470,"0,0107414717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,84","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_085,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),31392,377,31908,"0,0118152188",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,96","15,72"
"low bq, low freq, many artifacts, many samples",UPN2_086,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),25935,335,26401,"0,0126889133",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,79","15,3"
"low bq, low freq, many artifacts, many samples",UPN2_087,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),38055,418,38614,"0,0108250893",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,87","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_088,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),29566,315,30000,"0,0105",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"30,04","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_094,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),9207,111,9369,"0,0118475825",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,38","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_095,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),8483,97,8618,"0,0112555117",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,2","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_096,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),8323,108,8461,"0,0127644486",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,51","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_097,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),8909,107,9068,"0,0117997353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,52","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_098,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),7256,97,7392,"0,0131222944",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,35","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_099,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),4314,71,4399,"0,0161400318",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,08","14,1"
"low bq, low freq, many artifacts, many samples",UPN2_100,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),11569,121,11728,"0,0103171896",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,69","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_101,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),7834,103,7953,"0,0129510876",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,22","14,07"
"low bq, low freq, many artifacts, many samples",UPN2_102,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),7115,84,7217,"0,0116391853",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,26","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_103,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),11203,182,11431,"0,0159216167",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,17","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_104,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),10717,139,10892,"0,0127616599",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,29","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_105,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),10321,127,10480,"0,0121183206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,28","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_106,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),12133,151,12324,"0,0122525154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,47","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_107,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),12080,164,12283,"0,013351787",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,32","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_108,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),15691,205,15943,"0,0128583077",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,45","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_109,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),15170,190,15417,"0,0123240579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,31","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_110,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),12263,146,12438,"0,0117382216",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,36","14,27"
"low bq, low freq, many artifacts",UPN2_111,7,148508773,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile631Phe/c.1891A>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),10823,147,11010,"0,0133514986",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,2,Damaging,"29,31","14,27"
"inspected, bad alignment, many artifacts",UPN2_044,7,148508793,G,T,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser624Tyr/c.1871C>A|751|EZH2|protein_coding|CODING|ENST00000320356|16|T),4544,67,4621,"0,0144990262",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,23",Deleterious,0,Damaging,"34,07","30,58"
"inspected, bad alignment, many artifacts",UPN2_044,7,148508797,G,A,missense_variant(MODERATE|MISSENSE|Cca/Tca|p.Pro623Ser/c.1867C>T|751|EZH2|protein_coding|CODING|ENST00000320356|16|A),4544,66,4622,"0,0142795327",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,95",Deleterious,"0,002",Damaging,"33,69","33,5"
"inspected, bad alignment, many artifacts",UPN2_041,7,148508808,A,G,missense_variant(MODERATE|MISSENSE|cTa/cCa|p.Leu619Pro/c.1856T>C|751|EZH2|protein_coding|CODING|ENST00000320356|16|G),1747,52,1802,"0,0288568257",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,18",Deleterious,0,Damaging,34,"31,88"
"inspected, bad alignment, many artifacts",UPN2_048,7,148508809,G,T,missense_variant(MODERATE|MISSENSE|Cta/Ata|p.Leu619Ile/c.1855C>A|751|EZH2|protein_coding|CODING|ENST00000320356|16|T),6596,124,6736,"0,0184085511",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,002",Damaging,"34,1","30,69"
"inspected, bad alignment, many artifacts",UPN2_044,7,148511051,CT,C,frameshift_variant(HIGH||aag/|p.Lys617fs/c.1850delA|751|EZH2|protein_coding|CODING|ENST00000320356|15|C),2339,38,2416,"0,0157284768",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,01",NA
"inspected, bad alignment, many artifacts",UPN2_018,7,148511052,T,C,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys617Arg/c.1850A>G|751|EZH2|protein_coding|CODING|ENST00000320356|15|C),5969,61,6086,"0,0100230036",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,"0,043",Damaging,"35,26","35,57"
"low freq, many artifacts, many samples",UPN2_024,7,148511052,T,C,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys617Arg/c.1850A>G|751|EZH2|protein_coding|CODING|ENST00000320356|15|C),3644,38,3714,"0,0102315563",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,43,Damaging,"35,39","35,68"
"low freq, many artifacts, many samples",UPN2_044,7,148511052,T,C,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys617Arg/c.1850A>G|751|EZH2|protein_coding|CODING|ENST00000320356|15|C),2339,30,2416,"0,0124172185",0,0,0,0,0,0,0,1,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,43,Damaging,"35,01","33,73"
"low freq, many artifacts, many samples",UPN2_057,7,148511052,T,C,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys617Arg/c.1850A>G|751|EZH2|protein_coding|CODING|ENST00000320356|15|C),11940,125,12162,"0,0102779148",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,43,Damaging,"35,04","34,82"
"inspected, bad alignment, many artifacts",UPN2_044,7,148511067,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln612Leu/c.1835A>T|751|EZH2|protein_coding|CODING|ENST00000320356|15|A),2385,26,2416,"0,0107615894",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,18",Deleterious,0,Damaging,"35,02",35
"Not in 2nd Illumina, many artifacts, low freq",UPN2_006,7,148511070,A,G,missense_variant(MODERATE|MISSENSE|aTt/aCt|p.Ile611Thr/c.1832T>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),8347,92,8445,"0,0108940201",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,19",Deleterious,"0,001",Damaging,"35,7","35,72"
"low bq, low freq, many artifacts, many samples",UPN2_043,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),16148,173,16410,"0,0105423522",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"30,48","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_044,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),4671,50,4755,"0,0105152471",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"30,34","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_046,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),26634,271,27077,"0,0100084943",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"30,33","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_048,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),11069,115,11256,"0,0102167733",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"30,41","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_049,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),17223,187,17529,"0,0106680358",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"30,23","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_055,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),24881,260,25289,"0,0102811499",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"30,3","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_090,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),7827,87,7935,"0,0109640832",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"30,04","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_057,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),23567,246,23982,"0,0102576933",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"30,29",15
"low bq, low freq, many artifacts, many samples",UPN2_058,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),23691,262,24087,"0,0108772367",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"30,31","14,76"
"low bq, many samples",UPN2_059,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),15913,383,16372,"0,0233935988",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"29,45","14,54"
"low bq, many samples",UPN2_060,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),14240,348,14668,"0,0237251159",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"29,3","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_091,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),8749,96,8875,"0,0108169014",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"30,02","14,07"
"low bq, low freq, many artifacts, many samples",UPN2_092,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),5894,62,5973,"0,0103800435",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"29,9","14,47"
"low bq, many samples",UPN2_061,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),12193,301,12556,"0,0239726027",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"29,4","15,16"
"low bq, many samples",UPN2_062,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),9977,279,10309,"0,0270637307",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"29,3","14,54"
"low bq, many samples",UPN2_063,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),12402,303,12760,"0,0237460815",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"29,46","14,43"
"low bq, many samples",UPN2_064,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),12412,314,12764,"0,0246004387",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"29,26","14,71"
"low bq, many samples",UPN2_065,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),12450,305,12821,"0,023789096",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"29,41","14,58"
"low bq, many samples",UPN2_066,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),17527,439,18061,"0,0243065168",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"29,28","14,54"
"low bq, many samples",UPN2_067,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),18361,441,18912,"0,0233185279",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"29,4","14,52"
"low bq, many samples",UPN2_068,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),14005,376,14457,"0,0260081621",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"29,35","14,57"
"low bq, many samples",UPN2_069,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),16808,453,17334,"0,0261336102",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"29,3","14,53"
"low bq, many samples",UPN2_070,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),11385,306,11745,"0,0260536398",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"29,14","14,59"
"low bq, many samples",UPN2_071,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),8841,213,9094,"0,0234220365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"29,32","14,77"
"low bq, many samples",UPN2_072,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),11721,291,12086,"0,024077445",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"29,44","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_073,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),12816,271,13163,"0,0205880119",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"29,43","14,73"
"low bq, many samples",UPN2_074,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),9557,233,9853,"0,02364762",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"29,27","14,63"
"low bq, many samples",UPN2_075,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),16274,390,16753,"0,0232794126",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"29,35","14,43"
"low bq, many samples",UPN2_076,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),12655,308,13035,"0,023628692",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"29,33","14,51"
"low bq, many samples",UPN2_077,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),16559,406,17054,"0,0238067316",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"29,35","14,61"
"low bq, many samples",UPN2_078,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),13287,340,13682,"0,0248501681",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"29,18","14,59"
"low bq, many samples",UPN2_079,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),8506,193,8735,"0,02209502",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"29,35","14,8"
"low bq, many samples",UPN2_080,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),12757,356,13192,"0,0269860522",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"29,38","14,92"
"low bq, many samples",UPN2_081,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),16962,395,17424,"0,0226698806",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"29,42","14,77"
"low bq, many samples",UPN2_082,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),18402,489,18985,"0,0257571767",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"29,4","15,14"
"low bq, many samples",UPN2_083,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),18479,501,19049,"0,0263005932",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"29,29","14,49"
"low bq, many samples",UPN2_084,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),17488,503,18070,"0,0278361926",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"29,29","15,38"
"low bq, many samples",UPN2_085,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),13826,335,14225,"0,0235500879",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"29,37","14,41"
"low bq, many samples",UPN2_086,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),8977,223,9257,"0,0240898779",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"29,34","14,7"
"low bq, many samples",UPN2_087,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),17841,472,18410,"0,0256382401",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"29,34","14,69"
"low bq, many samples",UPN2_088,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),16453,402,16968,"0,0236916549",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"29,35","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_095,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),11228,117,11381,"0,0102802917",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"29,98","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_096,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),8800,96,8945,"0,0107322527",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"29,99","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_097,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),9767,104,9905,"0,0104997476",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"29,99","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_098,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),10890,111,11057,"0,0100388894",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"29,92","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_100,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),12310,137,12504,"0,0109564939",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"30,15","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_101,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),10754,130,10922,"0,0119025819",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"30,05","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_103,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),12014,125,12173,"0,0102686273",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"29,93","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_104,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),11911,136,12087,"0,0112517581",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"30,01","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_106,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),13889,158,14098,"0,0112072634",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"30,01","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_107,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),17802,233,18097,"0,0128750622",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"30,06","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_108,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),18505,212,18786,"0,0112849995",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"30,1","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_109,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),16810,196,17066,"0,0114848236",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"30,1","14,34"
"low bq, low freq, many artifacts",UPN2_110,7,148511139,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp588Ala/c.1763A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),13952,148,14155,"0,0104556694",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,1,Damaging,"30,09","14,43"
"inspected, bad alignment, many artifacts",UPN2_044,7,148511142,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro587His/c.1760C>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),4608,137,4757,"0,0287996637",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,2",Deleterious,0,Damaging,"33,35","33,15"
"low bq, low freq, many artifacts, many samples",UPN2_059,7,148511145,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp586Ala/c.1757A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),15995,287,16378,"0,0175235071",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,56",Deleterious,0,Damaging,"29,7","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_060,7,148511145,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp586Ala/c.1757A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),14311,280,14674,"0,0190813684",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,56",Deleterious,0,Damaging,"29,54","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_061,7,148511145,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp586Ala/c.1757A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),12278,223,12566,"0,0177462995",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,56",Deleterious,0,Damaging,"29,51","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_062,7,148511145,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp586Ala/c.1757A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),10087,172,10311,"0,0166812142",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,56",Deleterious,0,Damaging,"29,49","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_063,7,148511145,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp586Ala/c.1757A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),12430,244,12765,"0,0191147669",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,56",Deleterious,0,Damaging,"29,58","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_064,7,148511145,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp586Ala/c.1757A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),12473,217,12769,"0,016994283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,56",Deleterious,0,Damaging,"29,59","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_065,7,148511145,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp586Ala/c.1757A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),12528,237,12829,"0,0184737704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,56",Deleterious,0,Damaging,"29,64","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_066,7,148511145,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp586Ala/c.1757A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),17649,330,18071,"0,0182613026",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,56",Deleterious,0,Damaging,"29,47","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_067,7,148511145,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp586Ala/c.1757A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),18472,340,18921,"0,0179694519",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,56",Deleterious,0,Damaging,"29,56",15
"low bq, low freq, many artifacts, many samples",UPN2_068,7,148511145,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp586Ala/c.1757A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),14123,258,14465,"0,0178361562",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,56",Deleterious,0,Damaging,"29,51","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_069,7,148511145,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp586Ala/c.1757A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),16949,311,17346,"0,0179292056",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,56",Deleterious,0,Damaging,"29,51","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_070,7,148511145,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp586Ala/c.1757A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),11493,214,11749,"0,0182143161",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,56",Deleterious,0,Damaging,"29,44","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_071,7,148511145,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp586Ala/c.1757A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),8868,176,9106,"0,0193279157",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,56",Deleterious,0,Damaging,"29,63","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_072,7,148511145,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp586Ala/c.1757A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),11846,211,12093,"0,0174481105",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,56",Deleterious,0,Damaging,"29,56","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_073,7,148511145,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp586Ala/c.1757A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),12890,205,13167,"0,0155692261",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,56",Deleterious,0,Damaging,"29,44","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_074,7,148511145,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp586Ala/c.1757A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),9646,181,9863,"0,0183514144",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,56",Deleterious,0,Damaging,"29,49","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_075,7,148511145,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp586Ala/c.1757A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),16411,275,16758,"0,0164100728",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,56",Deleterious,0,Damaging,"29,63","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_076,7,148511145,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp586Ala/c.1757A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),12681,257,13044,"0,0197025452",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,56",Deleterious,0,Damaging,"29,52","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_077,7,148511145,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp586Ala/c.1757A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),16652,320,17057,"0,0187606261",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,56",Deleterious,0,Damaging,"29,47","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_078,7,148511145,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp586Ala/c.1757A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),13344,277,13689,"0,0202352254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,56",Deleterious,0,Damaging,"29,38","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_079,7,148511145,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp586Ala/c.1757A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),8524,180,8739,"0,0205973223",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,56",Deleterious,0,Damaging,"29,51","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_080,7,148511145,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp586Ala/c.1757A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),12882,231,13194,"0,0175079582",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,56",Deleterious,0,Damaging,"29,41","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_081,7,148511145,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp586Ala/c.1757A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),17053,281,17435,"0,016117006",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,56",Deleterious,0,Damaging,"29,7","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_082,7,148511145,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp586Ala/c.1757A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),18560,325,19001,"0,0171043629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,56",Deleterious,0,Damaging,"29,62","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_083,7,148511145,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp586Ala/c.1757A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),18615,355,19051,"0,0186341924",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,56",Deleterious,0,Damaging,"29,42","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_084,7,148511145,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp586Ala/c.1757A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),17652,329,18078,"0,0181989158",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,56",Deleterious,0,Damaging,"29,48","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_085,7,148511145,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp586Ala/c.1757A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),13875,253,14233,"0,0177755919",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,56",Deleterious,0,Damaging,"29,54","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_086,7,148511145,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp586Ala/c.1757A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),9046,169,9265,"0,0182406908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,56",Deleterious,0,Damaging,"29,43","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_087,7,148511145,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp586Ala/c.1757A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),17966,343,18420,"0,0186210641",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,56",Deleterious,0,Damaging,"29,53","14,74"
"low bq, low freq, many artifacts",UPN2_088,7,148511145,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp586Ala/c.1757A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),16596,303,16984,"0,0178403203",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,56",Deleterious,0,Damaging,"29,52","14,33"
"low bq, low freq, many artifacts",UPN2_048,7,148511147,A,T,stop_gained(HIGH|NONSENSE|tgT/tgA|p.Cys585*/c.1755T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),11089,113,11250,"0,0100444444",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,14","23,48"
"low bq, low freq, many artifacts",UPN2_044,7,148511170,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys578Ser/c.1732T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),4682,50,4766,"0,0104909778",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"30,82","18,08"
"low bq, low freq, many artifacts, many samples",UPN2_001,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),5571,57,5649,"0,0100902815",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"34,01","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_014,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),8120,110,8253,"0,0133284866",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"34,22","17,77"
"low bq, low freq, many artifacts, many samples",UPN2_018,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),5921,64,6006,"0,0106560107",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"34,23","18,94"
"low bq, low freq, many artifacts, many samples",UPN2_023,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),9016,95,9139,"0,0103950104",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"34,27","17,22"
"low bq, low freq, many artifacts, many samples",UPN2_042,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),12091,191,12315,"0,0155095412",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"33,34","17,42"
"low bq, low freq, many artifacts, many samples",UPN2_043,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),7983,138,8154,"0,016924209",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"33,23","17,26"
"low bq, low freq, many artifacts, many samples",UPN2_044,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),2329,31,2367,"0,0130967469",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"33,37","15,55"
"low bq, low freq, many artifacts, many samples",UPN2_005,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),1980,24,2010,"0,0119402985",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"34,06","17,17"
"low bq, low freq, many artifacts, many samples",UPN2_045,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),7180,118,7331,"0,0160960306",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"33,29","16,81"
"low bq, low freq, many artifacts, many samples",UPN2_046,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),13206,215,13458,"0,0159756279",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"33,34","17,21"
"low bq, low freq, many artifacts, many samples",UPN2_033,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),7592,77,7692,"0,0100104004",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"34,15","17,04"
"low bq, low freq, many artifacts, many samples",UPN2_047,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),14426,270,14742,"0,0183150183",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"33,22","18,02"
"low bq, low freq, many artifacts, many samples",UPN2_048,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),5496,91,5601,"0,0162470987",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"33,33","16,84"
"low bq, low freq, many artifacts, many samples",UPN2_049,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),8562,126,8710,"0,0144661309",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"33,35","16,16"
"low bq, low freq, many artifacts, many samples",UPN2_050,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),9930,158,10122,"0,0156095633",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"33,3","17,3"
"low bq, low freq, many artifacts, many samples",UPN2_051,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),11239,177,11462,"0,0154423312",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"33,31","17,52"
"low bq, low freq, many artifacts, many samples",UPN2_052,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),8093,105,8231,"0,0127566517",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"33,23","16,69"
"low bq, low freq, many artifacts, many samples",UPN2_053,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),13135,195,13368,"0,0145870736",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"33,35","17,6"
"low bq, low freq, many artifacts, many samples",UPN2_054,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),10114,141,10289,"0,0137039557",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"33,23","17,74"
"low bq, low freq, many artifacts, many samples",UPN2_010,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),14407,167,14631,"0,0114141207",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"34,02","17,58"
"low bq, low freq, many artifacts, many samples",UPN2_011,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),13984,144,14152,"0,0101752402",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"33,92","18,07"
"low bq, low freq, many artifacts, many samples",UPN2_055,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),12346,173,12560,"0,0137738854",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"33,41","16,86"
"low bq, low freq, many artifacts, many samples",UPN2_056,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),4119,57,4190,"0,0136038186",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"33,28","15,65"
"low bq, low freq, many artifacts, many samples",UPN2_057,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),11693,182,11912,"0,0152787105",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"33,22","16,92"
"low bq, low freq, many artifacts, many samples",UPN2_058,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),11705,184,11952,"0,015394913",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"33,32","16,9"
"low bq, low freq, many artifacts, many samples",UPN2_059,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),8020,82,8128,"0,0100885827",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"33,48","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_012,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),6749,87,6862,"0,0126785194",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"33,94","16,75"
"low bq, low freq, many artifacts, many samples",UPN2_060,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),7180,88,7295,"0,0120630569",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"33,52","17,14"
"low bq, low freq, many artifacts, many samples",UPN2_013,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),4395,48,4450,"0,0107865169",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"33,94","18,52"
"low bq, low freq, many artifacts, many samples",UPN2_061,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),6122,75,6217,"0,0120636963",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"33,47","16,12"
"low bq, low freq, many artifacts, many samples",UPN2_063,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),6248,75,6342,"0,0118259224",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"33,47","18,12"
"low bq, low freq, many artifacts, many samples",UPN2_066,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),8842,98,8961,"0,0109362794",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"33,31","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_067,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),9254,108,9388,"0,0115040477",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"33,49","15,71"
"low bq, low freq, many artifacts, many samples",UPN2_069,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),8487,87,8606,"0,0101092261",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"33,43","16,91"
"low bq, low freq, many artifacts, many samples",UPN2_070,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),5744,60,5829,"0,0102933608",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"33,39","18,18"
"low bq, low freq, many artifacts, many samples",UPN2_071,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),4454,50,4521,"0,0110595001",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"33,33","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_072,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),5920,65,6001,"0,0108315281",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"33,42","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_073,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),6451,80,6549,"0,0122156054",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"33,42","17,35"
"low bq, low freq, many artifacts, many samples",UPN2_074,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),4818,60,4896,"0,012254902",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"33,32","15,92"
"low bq, low freq, many artifacts, many samples",UPN2_077,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),8353,100,8472,"0,0118035883",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"33,49","16,2"
"low bq, low freq, many artifacts, many samples",UPN2_079,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),4265,45,4338,"0,010373444",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"33,51","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_081,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),8544,98,8662,"0,0113137843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"33,41","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_083,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),9305,106,9449,"0,0112181183",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"33,54","16,01"
"low bq, low freq, many artifacts, many samples",UPN2_085,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),6954,78,7059,"0,0110497238",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"33,47","16,03"
"low bq, low freq, many artifacts, many samples",UPN2_086,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),4541,48,4598,"0,0104393214",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"33,44","16,1"
"low bq, low freq, many artifacts, many samples",UPN2_087,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),9028,92,9155,"0,0100491535",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"33,38","17,46"
"low bq, low freq, many artifacts",UPN2_088,7,148511176,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys576Ser/c.1726T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),8298,107,8428,"0,012695776",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,44",Deleterious,0,Damaging,"33,35","17,18"
"low bq, low freq, many artifacts, many samples",UPN2_073,7,148511185,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr573Pro/c.1717A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),6453,79,6559,"0,012044519",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,1,Damaging,"29,82","15,52"
"low bq, low freq, many artifacts, many samples",UPN2_078,7,148511185,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr573Pro/c.1717A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),6723,69,6816,"0,0101232394",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,1,Damaging,"29,59","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_079,7,148511185,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr573Pro/c.1717A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),4279,54,4351,"0,01241094",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,1,Damaging,"30,03","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_083,7,148511185,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr573Pro/c.1717A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),9306,105,9459,"0,0111005392",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,1,Damaging,"29,73","14,3"
"low bq, low freq, many artifacts",UPN2_086,7,148511185,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr573Pro/c.1717A>C|751|EZH2|protein_coding|CODING|ENST00000320356|15|G),4544,49,4610,"0,0106290672",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,1,Damaging,"29,74","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_001,7,148511191,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys571Ser/c.1711T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),5561,67,5654,"0,0118500177",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,14",Deleterious,1,Damaging,"34,21","19,16"
"low bq, low freq, many artifacts, many samples",UPN2_014,7,148511191,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys571Ser/c.1711T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),8140,89,8257,"0,0107787332",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,14",Deleterious,1,Damaging,"34,46","17,17"
"low bq, low freq, many artifacts, many samples",UPN2_024,7,148511191,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys571Ser/c.1711T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),3623,37,3663,"0,0101010101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,14",Deleterious,1,Damaging,"34,4","18,78"
"low bq, low freq, many artifacts, many samples",UPN2_042,7,148511191,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys571Ser/c.1711T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),12099,182,12338,"0,0147511752",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,14",Deleterious,1,Damaging,"33,62","16,9"
"inspected, bad alignment, many artifacts",UPN2_043,7,148511191,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys571Ser/c.1711T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),7985,142,8173,"0,0173742812",0,0,0,0,1,0,1,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,14",Deleterious,"0,001",Damaging,"33,58","17,56"
"low bq, low freq, many artifacts, many samples",UPN2_044,7,148511191,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys571Ser/c.1711T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),2338,24,2373,"0,01011378",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,14",Deleterious,1,Damaging,"33,69","16,38"
"low bq, low freq, many artifacts, many samples",UPN2_045,7,148511191,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys571Ser/c.1711T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),7195,112,7342,"0,015254699",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,14",Deleterious,1,Damaging,"33,68","18,88"
"low bq, low freq, many artifacts, many samples",UPN2_046,7,148511191,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys571Ser/c.1711T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),13233,198,13484,"0,01468407",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,14",Deleterious,1,Damaging,"33,6","17,94"
"low bq, low freq, many artifacts, many samples",UPN2_033,7,148511191,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys571Ser/c.1711T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),7571,82,7695,"0,0106562703",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,14",Deleterious,1,Damaging,"34,36","18,83"
"low bq, low freq, many artifacts, many samples",UPN2_047,7,148511191,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys571Ser/c.1711T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),14460,212,14768,"0,0143553629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,14",Deleterious,1,Damaging,"33,63",19
"low bq, low freq, many artifacts, many samples",UPN2_048,7,148511191,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys571Ser/c.1711T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),5524,59,5609,"0,0105188091",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,14",Deleterious,1,Damaging,"33,56","17,47"
"low bq, low freq, many artifacts, many samples",UPN2_049,7,148511191,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys571Ser/c.1711T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),8557,125,8724,"0,0143282898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,14",Deleterious,1,Damaging,"33,63","19,01"
"low bq, low freq, many artifacts, many samples",UPN2_050,7,148511191,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys571Ser/c.1711T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),9957,128,10150,"0,0126108374",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,14",Deleterious,1,Damaging,"33,62","17,32"
"low bq, low freq, many artifacts, many samples",UPN2_051,7,148511191,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys571Ser/c.1711T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),11270,166,11488,"0,0144498607",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,14",Deleterious,1,Damaging,"33,6","18,09"
"low bq, low freq, many artifacts, many samples",UPN2_052,7,148511191,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys571Ser/c.1711T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),8081,117,8245,"0,0141904184",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,14",Deleterious,1,Damaging,"33,6","16,37"
"low bq, low freq, many artifacts, many samples",UPN2_053,7,148511191,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys571Ser/c.1711T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),13121,197,13394,"0,0147080782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,14",Deleterious,1,Damaging,"33,64","17,89"
"low bq, low freq, many artifacts, many samples",UPN2_054,7,148511191,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys571Ser/c.1711T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),10121,137,10310,"0,0132880698",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,14",Deleterious,1,Damaging,"33,66","17,2"
"low bq, low freq, many artifacts, many samples",UPN2_007,7,148511191,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys571Ser/c.1711T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),16666,178,16916,"0,0105225822",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,14",Deleterious,1,Damaging,"34,18","16,96"
"low bq, low freq, many artifacts, many samples",UPN2_011,7,148511191,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys571Ser/c.1711T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),13929,152,14161,"0,0107337052",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,14",Deleterious,1,Damaging,"34,21","18,14"
"low bq, low freq, many artifacts, many samples",UPN2_055,7,148511191,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys571Ser/c.1711T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),12351,163,12587,"0,0129498689",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,14",Deleterious,1,Damaging,"33,65","18,12"
"low bq, low freq, many artifacts, many samples",UPN2_056,7,148511191,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys571Ser/c.1711T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),4112,66,4194,"0,0157367668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,14",Deleterious,1,Damaging,"33,65","17,82"
"low bq, low freq, many artifacts, many samples",UPN2_057,7,148511191,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys571Ser/c.1711T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),11702,181,11938,"0,0151616686",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,14",Deleterious,1,Damaging,"33,54","17,43"
"low bq, low freq, many artifacts, many samples",UPN2_058,7,148511191,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys571Ser/c.1711T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),11767,154,11980,"0,0128547579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,14",Deleterious,1,Damaging,"33,6","16,75"
"low bq, low freq, many artifacts, many samples",UPN2_059,7,148511191,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys571Ser/c.1711T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),8033,84,8147,"0,0103105438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,14",Deleterious,1,Damaging,"33,85","15,79"
"low bq, low freq, many artifacts, many samples",UPN2_013,7,148511191,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys571Ser/c.1711T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),4379,56,4454,"0,0125729681",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,14",Deleterious,1,Damaging,"34,16","16,61"
"low bq, low freq, many artifacts, many samples",UPN2_062,7,148511191,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys571Ser/c.1711T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),5045,60,5125,"0,0117073171",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,14",Deleterious,1,Damaging,"34,02","18,78"
"low bq, low freq, many artifacts, many samples",UPN2_064,7,148511191,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys571Ser/c.1711T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),6267,68,6361,"0,0106901431",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,14",Deleterious,1,Damaging,"33,84","17,5"
"low bq, low freq, many artifacts, many samples",UPN2_067,7,148511191,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys571Ser/c.1711T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),9274,96,9405,"0,0102073365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,14",Deleterious,1,Damaging,"33,83","18,2"
"low bq, low freq, many artifacts, many samples",UPN2_072,7,148511191,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys571Ser/c.1711T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),5923,66,6014,"0,0109743931",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,14",Deleterious,1,Damaging,"33,86","15,85"
"low bq, low freq, many artifacts, many samples",UPN2_075,7,148511191,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys571Ser/c.1711T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),8235,86,8353,"0,0102957021",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,14",Deleterious,1,Damaging,"33,96","15,64"
"low bq, low freq, many artifacts, many samples",UPN2_085,7,148511191,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys571Ser/c.1711T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),6972,71,7072,"0,0100395928",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,14",Deleterious,1,Damaging,"33,77","16,86"
"low bq, low freq, many artifacts",UPN2_088,7,148511191,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys571Ser/c.1711T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),8330,90,8443,"0,0106597181",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,14",Deleterious,1,Damaging,"33,82","16,5"
"low bq, low freq, many artifacts, many samples",UPN2_042,7,148511217,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe562Tyr/c.1685T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),12128,156,12343,"0,0126387426",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,5,Damaging,"33,37","16,78"
"low bq, low freq, many artifacts, many samples",UPN2_043,7,148511217,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe562Tyr/c.1685T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),8037,101,8171,"0,0123607882",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,5,Damaging,"33,33","17,24"
"low bq, low freq, many artifacts, many samples",UPN2_044,7,148511217,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe562Tyr/c.1685T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),2335,29,2373,"0,0122208175",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,5,Damaging,"33,43","15,97"
"low bq, low freq, many artifacts, many samples",UPN2_045,7,148511217,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe562Tyr/c.1685T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),7215,86,7344,"0,0117102397",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,5,Damaging,"33,5","17,31"
"low bq, low freq, many artifacts, many samples",UPN2_046,7,148511217,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe562Tyr/c.1685T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),13275,149,13490,"0,0110452187",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,5,Damaging,"33,4","16,88"
"low bq, low freq, many artifacts, many samples",UPN2_048,7,148511217,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe562Tyr/c.1685T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),5523,65,5611,"0,0115843878",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,5,Damaging,"33,31","15,69"
"low bq, low freq, many artifacts, many samples",UPN2_049,7,148511217,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe562Tyr/c.1685T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),8600,101,8725,"0,0115759312",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,5,Damaging,"33,35","18,37"
"low bq, low freq, many artifacts, many samples",UPN2_050,7,148511217,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe562Tyr/c.1685T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),9942,143,10152,"0,0140858944",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,5,Damaging,"33,35","19,66"
"low bq, low freq, many artifacts, many samples",UPN2_051,7,148511217,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe562Tyr/c.1685T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),11291,126,11494,"0,0109622412",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,5,Damaging,"33,42","16,21"
"low bq, low freq, many artifacts, many samples",UPN2_052,7,148511217,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe562Tyr/c.1685T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),8124,86,8249,"0,0104255061",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,5,Damaging,"33,28","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_053,7,148511217,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe562Tyr/c.1685T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),13159,159,13398,"0,0118674429",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,5,Damaging,"33,27","16,5"
"low bq, low freq, many artifacts, many samples",UPN2_054,7,148511217,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe562Tyr/c.1685T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),10144,129,10318,"0,012502423",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,5,Damaging,"33,24","17,11"
"low bq, low freq, many artifacts, many samples",UPN2_007,7,148511217,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe562Tyr/c.1685T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),16672,176,16916,"0,0104043509",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,5,Damaging,"33,84","17,31"
"low bq, low freq, many artifacts, many samples",UPN2_055,7,148511217,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe562Tyr/c.1685T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),12391,138,12595,"0,0109567289",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,5,Damaging,"33,35","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_056,7,148511217,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe562Tyr/c.1685T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),4103,55,4196,"0,0131077216",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,5,Damaging,"33,29","15,69"
"low bq, low freq, many artifacts, many samples",UPN2_057,7,148511217,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe562Tyr/c.1685T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),11724,151,11942,"0,0126444482",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,5,Damaging,"33,35","16,23"
"low bq, low freq, many artifacts",UPN2_058,7,148511217,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe562Tyr/c.1685T>A|751|EZH2|protein_coding|CODING|ENST00000320356|15|T),11806,127,11987,"0,010594811",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,5,Damaging,"33,22","15,94"
"inspected, bad alignment, many artifacts",UPN2_044,7,148512012,A,T,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser556Thr/c.1666T>A|751|EZH2|protein_coding|CODING|ENST00000320356|14|T),2775,43,2822,"0,0152374203",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,88",Neutral,"0,181",Tolerated,"34,77","33,44"
"inspected, bad alignment, many artifacts",UPN2_056,7,148512018,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys554Ser/c.1660T>A|751|EZH2|protein_coding|CODING|ENST00000320356|14|T),1979,32,2028,"0,0157790927",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,81",Deleterious,0,Damaging,"35,56",36
"inspected, bad alignment, many artifacts",UPN2_056,7,148512020,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln553Leu/c.1658A>T|751|EZH2|protein_coding|CODING|ENST00000320356|14|A),1988,32,2028,"0,0157790927",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,"0,027",Damaging,"35,32","35,31"
"inspected, bad alignment, many artifacts",UPN2_045,7,148512029,T,C,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys550Arg/c.1649A>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),16726,182,16956,"0,0107336636",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,64",Deleterious,0,Damaging,"35,34","34,91"
"inspected, bad alignment, many artifacts",UPN2_054,7,148512029,T,C,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys550Arg/c.1649A>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),11297,118,11451,"0,0103047769",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,64",Deleterious,0,Damaging,"35,34","34,7"
"inspected, bad alignment, many artifacts",UPN2_056,7,148512029,T,C,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys550Arg/c.1649A>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),1993,28,2028,"0,0138067061",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,64",Deleterious,0,Damaging,"35,4","35,18"
"inspected, bad alignment, many artifacts",UPN2_093,7,148512029,T,C,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys550Arg/c.1649A>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),5115,59,5178,"0,0113943608",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,64",Deleterious,0,Damaging,"35,55","35,47"
"inspected, bad alignment, many artifacts",UPN2_056,7,148512037,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe547Leu/c.1641T>A|751|EZH2|protein_coding|CODING|ENST00000320356|14|T),1995,27,2028,"0,0133136095",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,22",Deleterious,"0,065",Tolerated,"35,59","35,85"
"inspected, bad alignment, many artifacts",UPN2_056,7,148512053,A,G,missense_variant(MODERATE|MISSENSE|gTg/gCg|p.Val542Ala/c.1625T>C|751|EZH2|protein_coding|CODING|ENST00000320356|14|G),1977,28,2027,"0,0138135175",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,36",Deleterious,"0,028",Damaging,"33,84","33,32"
"low freq, many artifacts",UPN2_056,7,148512053,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val542Glu/c.1625T>A|751|EZH2|protein_coding|CODING|ENST00000320356|14|T),1977,22,2027,"0,010853478",0,0,0,0,0,0,0,1,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,7,Damaging,"33,84","35,18"
"inspected, bad alignment, many artifacts",UPN2_056,7,148512055,A,T,stop_gained(HIGH|NONSENSE|tgT/tgA|p.Cys541*/c.1623T>A|751|EZH2|protein_coding|CODING|ENST00000320356|14|T),1975,41,2028,"0,0202169625",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,52","34,73"
inspected,UPN2_048,7,148512065,G,A,missense_variant(MODERATE|MISSENSE|tCg/tTg|p.Ser538Leu/c.1613C>T|751|EZH2|protein_coding|CODING|ENST00000320356|14|A),964,36,1003,"0,035892323",0,0,0,0,1,0,0,1,2,NO,NO,COSM122927,"skin, upper_aerodigestive_tract","1, 1",NO,NO,NO,NO,NO,NO,"-3,56",Deleterious,"0,042",Damaging,"34,08","35,67"
"low bq, low freq, many artifacts, many samples",UPN2_042,7,148512072,C,A,missense_variant(MODERATE|MISSENSE|Gac/Tac|p.Asp536Tyr/c.1606G>T|751|EZH2|protein_coding|CODING|ENST00000320356|14|A),24798,324,25227,"0,0128433821",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"31,43","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_043,7,148512072,C,A,missense_variant(MODERATE|MISSENSE|Gac/Tac|p.Asp536Tyr/c.1606G>T|751|EZH2|protein_coding|CODING|ENST00000320356|14|A),23213,265,23581,"0,011237861",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"31,46","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_044,7,148512072,C,A,missense_variant(MODERATE|MISSENSE|Gac/Tac|p.Asp536Tyr/c.1606G>T|751|EZH2|protein_coding|CODING|ENST00000320356|14|A),5460,56,5525,"0,0101357466",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"31,44","14,12"
"low bq, low freq, many artifacts, many samples",UPN2_045,7,148512072,C,A,missense_variant(MODERATE|MISSENSE|Gac/Tac|p.Asp536Tyr/c.1606G>T|751|EZH2|protein_coding|CODING|ENST00000320356|14|A),32571,355,33042,"0,0107439017",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"31,53","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_046,7,148512072,C,A,missense_variant(MODERATE|MISSENSE|Gac/Tac|p.Asp536Tyr/c.1606G>T|751|EZH2|protein_coding|CODING|ENST00000320356|14|A),28474,299,28874,"0,010355337",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"31,51","15,39"
"low bq, low freq, many artifacts, many samples",UPN2_047,7,148512072,C,A,missense_variant(MODERATE|MISSENSE|Gac/Tac|p.Asp536Tyr/c.1606G>T|751|EZH2|protein_coding|CODING|ENST00000320356|14|A),28299,319,28759,"0,0110921798",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"31,34","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_048,7,148512072,C,A,missense_variant(MODERATE|MISSENSE|Gac/Tac|p.Asp536Tyr/c.1606G>T|751|EZH2|protein_coding|CODING|ENST00000320356|14|A),1932,22,1962,"0,0112130479",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"31,48",17
"low bq, low freq, many artifacts, many samples",UPN2_049,7,148512072,C,A,missense_variant(MODERATE|MISSENSE|Gac/Tac|p.Asp536Tyr/c.1606G>T|751|EZH2|protein_coding|CODING|ENST00000320356|14|A),18663,224,18973,"0,011806251",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"31,44","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_050,7,148512072,C,A,missense_variant(MODERATE|MISSENSE|Gac/Tac|p.Asp536Tyr/c.1606G>T|751|EZH2|protein_coding|CODING|ENST00000320356|14|A),29392,332,29851,"0,0111219055",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"31,48","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_051,7,148512072,C,A,missense_variant(MODERATE|MISSENSE|Gac/Tac|p.Asp536Tyr/c.1606G>T|751|EZH2|protein_coding|CODING|ENST00000320356|14|A),23043,264,23413,"0,011275787",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"31,44","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_052,7,148512072,C,A,missense_variant(MODERATE|MISSENSE|Gac/Tac|p.Asp536Tyr/c.1606G>T|751|EZH2|protein_coding|CODING|ENST00000320356|14|A),24553,252,24897,"0,0101217014",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"31,53","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_053,7,148512072,C,A,missense_variant(MODERATE|MISSENSE|Gac/Tac|p.Asp536Tyr/c.1606G>T|751|EZH2|protein_coding|CODING|ENST00000320356|14|A),34643,364,35143,"0,0103576815",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"31,61","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_055,7,148512072,C,A,missense_variant(MODERATE|MISSENSE|Gac/Tac|p.Asp536Tyr/c.1606G>T|751|EZH2|protein_coding|CODING|ENST00000320356|14|A),32071,341,32561,"0,0104726513",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"31,51","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_056,7,148512072,C,A,missense_variant(MODERATE|MISSENSE|Gac/Tac|p.Asp536Tyr/c.1606G>T|751|EZH2|protein_coding|CODING|ENST00000320356|14|A),3900,54,3964,"0,0136226034",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"31,6","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_057,7,148512072,C,A,missense_variant(MODERATE|MISSENSE|Gac/Tac|p.Asp536Tyr/c.1606G>T|751|EZH2|protein_coding|CODING|ENST00000320356|14|A),32943,363,33397,"0,0108692398",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"31,36","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_058,7,148512072,C,A,missense_variant(MODERATE|MISSENSE|Gac/Tac|p.Asp536Tyr/c.1606G>T|751|EZH2|protein_coding|CODING|ENST00000320356|14|A),27451,299,27864,"0,0107306919",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"31,44","15,35"
"low bq, low freq, many artifacts",UPN2_062,7,148512072,C,A,missense_variant(MODERATE|MISSENSE|Gac/Tac|p.Asp536Tyr/c.1606G>T|751|EZH2|protein_coding|CODING|ENST00000320356|14|A),11344,133,11543,"0,0115221346",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,12",Deleterious,0,Damaging,"31,05","21,56"
"low bq, low freq, many artifacts",UPN2_051,7,148512094,A,T,stop_gained(HIGH|NONSENSE|tgT/tgA|p.Cys528*/c.1584T>A|751|EZH2|protein_coding|CODING|ENST00000320356|14|T),23316,253,23692,"0,0106787101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,04","21,9"
"inspected, bad alignment, many artifacts",UPN2_056,7,148512094,A,T,stop_gained(HIGH|NONSENSE|tgT/tgA|p.Cys528*/c.1584T>A|751|EZH2|protein_coding|CODING|ENST00000320356|14|T),3937,50,4009,"0,0124719381",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,88","25,88"
"inspected, bad alignment, many artifacts",UPN2_044,7,148512123,A,G,missense_variant(MODERATE|MISSENSE|Tct/Cct|p.Ser519Pro/c.1555T>C|751|EZH2|protein_coding|CODING|ENST00000320356|14|G),5513,57,5588,"0,0102004295",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-4,07",Deleterious,"0,024",Damaging,"33,65","32,21"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_089,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),18362,377,18826,"0,0200254967",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,63,Tolerated,"26,27","14,3"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_090,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),13702,244,14017,"0,0174074338",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,63,Tolerated,"26,18","14,37"
"low bq, bad alignment, many samples",UPN2_059,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),9797,1018,10906,"0,0933431139",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,63,Tolerated,"26,41","14,99"
"low bq, bad alignment, many samples",UPN2_060,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),14873,1509,16491,"0,091504457",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,63,Tolerated,"26,55","14,83"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_091,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),15587,311,15967,"0,0194776727",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,63,Tolerated,"26,27","14,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_092,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),11325,223,11618,"0,0191943536",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,63,Tolerated,"26,21","14,35"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_093,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),9999,170,10219,"0,0166356786",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,63,Tolerated,"26,31","14,27"
"low bq, bad alignment, many samples",UPN2_061,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),13935,1556,15627,"0,0995712549",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,63,Tolerated,"26,46","14,94"
"low bq, bad alignment, many samples",UPN2_062,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),10302,1239,11629,"0,1065439849",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,63,Tolerated,"26,45","15,05"
"low bq, bad alignment, many samples",UPN2_063,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),13393,1409,14942,"0,0942979521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,63,Tolerated,"26,39","14,96"
"low bq, bad alignment, many samples",UPN2_064,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),8453,924,9429,"0,0979955457",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,63,Tolerated,"26,38","14,94"
"low bq, bad alignment, many samples",UPN2_065,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),11695,1272,13096,"0,0971288943",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,63,Tolerated,"26,55","15,12"
"low bq, many samples, no database",UPN2_066,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),26661,2656,29591,"0,0897570207",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,063",Tolerated,"26,51","15,01"
"low bq, many samples, no database",UPN2_067,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),33238,3193,36713,"0,0869719173",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,063",Tolerated,"26,59","14,87"
"low bq, many samples, no database",UPN2_068,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),21371,2498,24066,"0,1037978891",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,063",Tolerated,"26,45","14,95"
"low bq, bad alignment, many samples",UPN2_069,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),22681,2593,25515,"0,1016264942",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,63,Tolerated,"26,51","14,93"
"low bq, many samples, no database",UPN2_070,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),13716,1620,15490,"0,1045836023",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,063",Tolerated,"26,47","14,97"
"low bq, bad alignment, many samples",UPN2_071,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),10155,1117,11368,"0,0982582688",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,63,Tolerated,"26,56","14,81"
"low bq, many samples, no database",UPN2_072,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),9811,1041,10961,"0,0949730864",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,063",Tolerated,"26,38","15,13"
"low bq, bad alignment, many samples",UPN2_073,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),11036,1105,12223,"0,090403338",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,63,Tolerated,"26,53","14,94"
"low bq, many samples, no database",UPN2_074,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),14130,1527,15775,"0,0967987322",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,063",Tolerated,"26,57","15,01"
"low bq, bad alignment, many samples",UPN2_075,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),20283,1844,22295,"0,0827091276",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,63,Tolerated,"26,49","14,91"
"low bq, many samples, no database",UPN2_076,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),15997,1922,18072,"0,1063523683",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,063",Tolerated,"26,51","15,02"
"low bq, bad alignment, many samples",UPN2_077,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),22997,2554,25770,"0,0991074893",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,63,Tolerated,"26,4","14,92"
"low bq, many samples, no database",UPN2_078,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),15339,1788,17275,"0,1035021708",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,063",Tolerated,"26,46","14,86"
"low bq, bad alignment, many samples",UPN2_079,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),10190,1110,11375,"0,0975824176",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,63,Tolerated,"26,58","14,72"
"low bq, many samples, no database",UPN2_080,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),14164,1586,15887,"0,0998300497",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,063",Tolerated,"26,52","14,84"
"low bq, bad alignment, many samples",UPN2_081,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),11458,1208,12792,"0,0944340213",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,63,Tolerated,"26,45","14,97"
"low bq, many samples, no database",UPN2_082,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),26017,2631,28891,"0,0910664221",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,063",Tolerated,"26,52","14,87"
"low bq, many samples, no database",UPN2_083,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),22966,2732,25908,"0,105450054",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,063",Tolerated,"26,42","14,86"
"low bq, many samples, no database",UPN2_084,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),20893,2449,23532,"0,1040710522",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,063",Tolerated,"26,51","14,89"
"low bq, bad alignment, many samples",UPN2_085,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),22133,2412,24753,"0,0974427342",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,63,Tolerated,"26,51","14,93"
"low bq, bad alignment, many samples",UPN2_086,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),18646,2197,21038,"0,1044300789",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,63,Tolerated,"26,41","15,02"
"low bq, bad alignment, many samples",UPN2_087,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),27646,3015,30943,"0,0974372233",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,63,Tolerated,"26,55","14,87"
"low bq, many samples, no database",UPN2_088,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),18972,1820,20953,"0,08686107",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,063",Tolerated,"26,51","14,86"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_094,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),19373,382,19830,"0,0192637418",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,63,Tolerated,"26,23","14,41"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_095,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),17836,395,18321,"0,0215599585",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,63,Tolerated,"26,19","14,25"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_096,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),20097,359,20565,"0,0174568442",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,63,Tolerated,"26,27","14,34"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_097,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),18619,367,19098,"0,0192166719",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,63,Tolerated,"26,15","14,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_098,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),17269,292,17664,"0,0165307971",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,63,Tolerated,"26,24",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_099,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),10255,209,10523,"0,0198612563",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,63,Tolerated,"26,22","14,44"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_100,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),15048,271,15393,"0,0176054051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,63,Tolerated,"26,16","14,59"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_101,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),16732,339,17191,"0,0197196207",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,63,Tolerated,"26,09","14,46"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_102,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),18936,384,19418,"0,0197754661",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,63,Tolerated,"26,13","14,19"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_103,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),16750,341,17178,"0,0198509722",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,63,Tolerated,"26,02","14,14"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_104,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),21288,455,21844,"0,0208295184",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,63,Tolerated,"26,17","14,27"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_105,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),16467,330,16900,"0,0195266272",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,63,Tolerated,"26,15","14,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_106,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),22906,448,23477,"0,0190825063",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,63,Tolerated,"26,17","14,73"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_107,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),33987,648,34804,"0,0186185496",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,63,Tolerated,"26,17","14,35"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_108,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),25682,486,26286,"0,0184889295",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,63,Tolerated,"26,23","14,3"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_109,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),26797,553,27485,"0,0201200655",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,63,Tolerated,"26,15","14,33"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_110,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),27390,554,28088,"0,0197237254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,63,Tolerated,"26,11","14,42"
"low bq, bad alignment",UPN2_111,7,148512126,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser518Ala/c.1552T>G|751|EZH2|protein_coding|CODING|ENST00000320356|14|C),22729,538,23363,"0,0230278646",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,63,Tolerated,"26,19","14,33"
"low freq, many artifacts",UPN2_056,7,148512129,C,T,missense_variant(MODERATE|MISSENSE|Ggc/Agc|p.Gly517Ser/c.1549G>A|751|EZH2|protein_coding|CODING|ENST00000320356|14|T),1963,21,1993,"0,0105368791",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"1,62",Neutral,"0,92",Tolerated,"33,48","32,9"
"bad alignment, low freq",UPN2_047,7,148512601,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys515Glu/c.1543A>G|751|EZH2|protein_coding|CODING|ENST00000320356|13|C),1058,22,1085,"0,0202764977",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,38",Deleterious,"0,003",Damaging,"34,78","33,82"
inspected many artifacts,UPN2_044,7,148512606,A,G,missense_variant(MODERATE|MISSENSE|cTg/cCg|p.Leu513Pro/c.1538T>C|751|EZH2|protein_coding|CODING|ENST00000320356|13|G),1542,28,1573,"0,0178003814",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,88",Deleterious,"0,002",Damaging,"33,64","33,5"
"Not in 2nd Illumina, many artifacts, low freq",UPN2_006,7,148512606,A,G,missense_variant(MODERATE|MISSENSE|cTg/cCg|p.Leu513Pro/c.1538T>C|751|EZH2|protein_coding|CODING|ENST00000320356|13|G),1682,39,1722,"0,0226480836",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,88",Deleterious,"0,002",Damaging,"34,1","32,87"
inspected many artifacts,UPN2_064,7,148512621,C,A,missense_variant(MODERATE|MISSENSE|tGc/tTc|p.Cys508Phe/c.1523G>T|751|EZH2|protein_coding|CODING|ENST00000320356|13|A),828,22,852,"0,0258215962",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,73",Deleterious,"0,001",Damaging,"34,46","33,45"
inspected many artifacts,UPN2_041,7,148513816,C,T,missense_variant(MODERATE|MISSENSE|Gat/Aat|p.Asp489Asn/c.1465G>A|751|EZH2|protein_coding|CODING|ENST00000320356|12|T),1298,26,1330,"0,0195488722",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,"0,073",Tolerated,"33,69",36
inspected many artifacts,UPN2_041,7,148513819,C,T,missense_variant(MODERATE|MISSENSE|Gag/Aag|p.Glu488Lys/c.1462G>A|751|EZH2|protein_coding|CODING|ENST00000320356|12|T),1278,48,1330,"0,0360902256",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,"0,515",Tolerated,"33,8","33,65"
inspected many artifacts,UPN2_044,7,148514334,C,A,missense_variant(MODERATE|MISSENSE|Ggg/Tgg|p.Gly464Trp/c.1390G>T|751|EZH2|protein_coding|CODING|ENST00000320356|11|A),1549,21,1570,"0,0133757962",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,23",Neutral,"0,024",Damaging,"35,18",36
inspected many artifacts,UPN2_044,7,148514346,C,T,missense_variant(MODERATE|MISSENSE|Gct/Act|p.Ala460Thr/c.1378G>A|751|EZH2|protein_coding|CODING|ENST00000320356|11|T),1517,52,1570,"0,0331210191",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,33",Deleterious,"0,002",Damaging,"34,38","35,02"
"inspected, many artifacts",UPN2_072,7,148514358,A,G,missense_variant(MODERATE|MISSENSE|Ttc/Ctc|p.Phe456Leu/c.1366T>C|751|EZH2|protein_coding|CODING|ENST00000320356|11|G),3074,32,3107,"0,0102993241",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,"0,156",Tolerated,"34,9","34,78"
inspected many artifacts,UPN2_044,7,148514375,C,T,missense_variant(MODERATE|MISSENSE|gGc/gAc|p.Gly450Asp/c.1349G>A|751|EZH2|protein_coding|CODING|ENST00000320356|11|T),3047,34,3092,"0,010996119",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,68",Neutral,"0,275",Tolerated,"31,14","32,71"
inspected many artifacts,UPN2_056,7,148514393,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met444Lys/c.1331T>A|751|EZH2|protein_coding|CODING|ENST00000320356|11|T),3099,36,3142,"0,0114576703",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,98",Deleterious,0,Damaging,"33,4","31,47"
inspected many artifacts,UPN2_048,7,148514397,A,G,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser443Pro/c.1327T>C|751|EZH2|protein_coding|CODING|ENST00000320356|11|G),1771,47,1824,"0,0257675439",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,15",Deleterious,"0,003",Damaging,"33,42","28,87"
"Not in 2nd Illumina, many artifacts, low freq",UPN2_006,7,148514397,A,G,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser443Pro/c.1327T>C|751|EZH2|protein_coding|CODING|ENST00000320356|11|G),6942,73,7036,"0,0103752132",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,15",Deleterious,"0,003",Damaging,"34,23","33,25"
inspected many artifacts,UPN2_056,7,148514440,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn428Lys/c.1284T>A|751|EZH2|protein_coding|CODING|ENST00000320356|11|T),1540,23,1565,"0,0146964856",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,"0,151",Tolerated,"34,15","35,35"
inspected many artifacts,UPN2_044,7,148514453,T,C,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys424Arg/c.1271A>G|751|EZH2|protein_coding|CODING|ENST00000320356|11|C),1505,34,1541,"0,0220635951",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,"0,175",Tolerated,"34,66","33,97"
"Not in 2nd Illumina, many artifacts, low freq",UPN2_006,7,148514471,C,T,missense_variant(MODERATE|MISSENSE|cGg/cAg|p.Arg418Gln/c.1253G>A|751|EZH2|protein_coding|CODING|ENST00000320356|11|T),3451,35,3498,"0,0100057176",0,0,0,0,1,0,0,1,2,NO,NO,COSM3259655,large_intestine,2,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,"0,047",Damaging,"34,86","35,89"
"inspected, TC repeat",UPN2_048,7,148514990,C,T,missense_variant(MODERATE|MISSENSE|Gat/Aat|p.Asp407Asn/c.1219G>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),587,41,630,"0,0650793651",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,31",Neutral,"0,127",Tolerated,"34,33","35,9"
"inspected, TC repeat",UPN2_076,7,148514997,CTCT,C,disruptive_inframe_deletion(MODERATE||gaagag/gag|p.Glu404del/c.1209_1211delAGA|751|EZH2|protein_coding|CODING|ENST00000320356|10|C),2920,32,2960,"0,0108108108",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"3,30E-005",NO,NO,"-0,46",Neutral,NA,NA,"34,97",NA
"inspected, TC repeat",UPN2_048,7,148515007,T,C,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu401Gly/c.1202A>G|751|EZH2|protein_coding|CODING|ENST00000320356|10|C),603,26,630,"0,0412698413",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,"0,34",Tolerated,"34,57","30,92"
"low bq, low freq, many artifacts, many samples",UPN2_050,7,148515014,C,A,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp399Tyr/c.1195G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),6317,68,6400,"0,010625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,14,Damaging,"32,17","14,1"
"low bq, low freq, many artifacts, many samples",UPN2_055,7,148515014,C,A,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp399Tyr/c.1195G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),7249,84,7347,"0,0114332381",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,14,Damaging,"32,02","14,25"
"6C, ins and del, many artifacts",UPN2_036,7,148515024,T,TC,frameshift_variant(HIGH||gga/ggGa|p.Glu396fs/c.1184dupG|751|EZH2|protein_coding|CODING|ENST00000320356|10|TC),3877,53,3924,"0,0135066259",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,7",NA
"6C, ins and del, many artifacts",UPN2_039,7,148515024,T,TC,frameshift_variant(HIGH||gga/ggGa|p.Glu396fs/c.1184dupG|751|EZH2|protein_coding|CODING|ENST00000320356|10|TC),3945,59,3994,"0,0147721582",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,55",NA
"low freq, many artifacts, many samples",UPN2_042,7,148515024,TC,T,frameshift_variant(HIGH||gga/|p.Gly395fs/c.1184delG|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),5942,61,6049,"0,0100843115",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,23",NA
"6C, ins and del, many artifacts",UPN2_045,7,148515024,TC,T,frameshift_variant(HIGH||gga/|p.Gly395fs/c.1184delG|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),6362,66,6471,"0,010199351",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,12",NA
"6C, ins and del, many artifacts",UPN2_036,7,148515024,TC,T,frameshift_variant(HIGH||gga/|p.Gly395fs/c.1184delG|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),3860,47,3924,"0,0119775739",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,68",NA
"6C, ins and del, many artifacts",UPN2_060,7,148515024,TC,T,frameshift_variant(HIGH||gga/|p.Gly395fs/c.1184delG|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),2820,34,2871,"0,0118425636",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,12",NA
"6C, ins and del, many artifacts",UPN2_040,7,148515024,TC,T,frameshift_variant(HIGH||gga/|p.Gly395fs/c.1184delG|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),2352,24,2385,"0,0100628931",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,71",NA
"6C, ins and del, many artifacts",UPN2_082,7,148515024,TC,T,frameshift_variant(HIGH||gga/|p.Gly395fs/c.1184delG|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),4107,44,4172,"0,0105465005",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,98",NA
"6C, ins and del, many artifacts, not in 2nd Illumina",UPN2_086,7,148515024,TC,T,frameshift_variant(HIGH||gga/|p.Gly395fs/c.1184delG|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),2303,25,2342,"0,0106746371",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,87",NA
"low bq, low freq, many artifacts, many samples",UPN2_043,7,148515026,C,A,stop_gained(HIGH|NONSENSE|Gga/Tga|p.Gly395*/c.1183G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),4798,52,4859,"0,0107017905",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,77","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_049,7,148515026,C,A,stop_gained(HIGH|NONSENSE|Gga/Tga|p.Gly395*/c.1183G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),3604,39,3651,"0,0106820049",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,83","16,51"
"low bq, low freq, many artifacts, many samples",UPN2_051,7,148515026,C,A,stop_gained(HIGH|NONSENSE|Gga/Tga|p.Gly395*/c.1183G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),5229,58,5299,"0,0109454614",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,71","16,09"
"low bq, low freq, many artifacts, many samples",UPN2_053,7,148515026,C,A,stop_gained(HIGH|NONSENSE|Gga/Tga|p.Gly395*/c.1183G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),7751,83,7866,"0,0105517417",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,78","17,22"
"low bq, low freq, many artifacts, many samples",UPN2_057,7,148515026,C,A,stop_gained(HIGH|NONSENSE|Gga/Tga|p.Gly395*/c.1183G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),6181,84,6279,"0,0133779264",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,68","18,64"
"low bq, low freq, many artifacts, many samples",UPN2_067,7,148515026,C,A,stop_gained(HIGH|NONSENSE|Gga/Tga|p.Gly395*/c.1183G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),4132,49,4186,"0,0117056856",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,36","16,78"
"low bq, low freq, many artifacts, many samples",UPN2_068,7,148515026,C,A,stop_gained(HIGH|NONSENSE|Gga/Tga|p.Gly395*/c.1183G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),2782,33,2821,"0,0116979794",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,66","16,94"
"low bq, low freq, many artifacts, many samples",UPN2_069,7,148515026,C,A,stop_gained(HIGH|NONSENSE|Gga/Tga|p.Gly395*/c.1183G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),3682,42,3736,"0,01124197",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,47","18,12"
"low bq, low freq, many artifacts, many samples",UPN2_072,7,148515026,C,A,stop_gained(HIGH|NONSENSE|Gga/Tga|p.Gly395*/c.1183G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),2666,27,2695,"0,0100185529",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,46","18,07"
"low bq, low freq, many artifacts, many samples",UPN2_073,7,148515026,C,A,stop_gained(HIGH|NONSENSE|Gga/Tga|p.Gly395*/c.1183G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),2442,27,2472,"0,0109223301",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,32","16,44"
"low bq, low freq, many artifacts, many samples",UPN2_075,7,148515026,C,A,stop_gained(HIGH|NONSENSE|Gga/Tga|p.Gly395*/c.1183G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),4274,55,4335,"0,0126874279",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,31","15,91"
"low bq, low freq, many artifacts, many samples",UPN2_079,7,148515026,C,A,stop_gained(HIGH|NONSENSE|Gga/Tga|p.Gly395*/c.1183G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),2157,24,2185,"0,0109839817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,54","17,5"
"low bq, low freq, many artifacts, many samples",UPN2_085,7,148515026,C,A,stop_gained(HIGH|NONSENSE|Gga/Tga|p.Gly395*/c.1183G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),3023,34,3072,"0,0110677083",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,61","16,32"
"low bq, low freq, many artifacts, many samples",UPN2_087,7,148515026,C,A,stop_gained(HIGH|NONSENSE|Gga/Tga|p.Gly395*/c.1183G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),4778,73,4854,"0,015039143",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,33","16,9"
"low bq, low freq, many artifacts",UPN2_088,7,148515026,C,A,stop_gained(HIGH|NONSENSE|Gga/Tga|p.Gly395*/c.1183G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),3028,42,3079,"0,0136407925",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,34","20,19"
"low bq, low freq, many artifacts",UPN2_071,7,148515028,C,A,missense_variant(MODERATE|MISSENSE|gGg/gTg|p.Gly394Val/c.1181G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),2966,31,3002,"0,010326449",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,93,Tolerated,"31,18","16,71"
"inspected, TC repeat",UPN2_048,7,148515028,C,T,missense_variant(MODERATE|MISSENSE|gGg/gAg|p.Gly394Glu/c.1181G>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),587,39,629,"0,0620031797",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,63",Neutral,"0,134",Tolerated,"32,78","34,21"
"low bq, low freq, many artifacts",UPN2_086,7,148515032,T,A,missense_variant(MODERATE|MISSENSE|Acg/Tcg|p.Thr393Ser/c.1177A>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),2303,24,2339,"0,0102607952",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,18",Neutral,529,Tolerated,"32,58","17,67"
"low bq, low freq, many artifacts",UPN2_006,7,148515038,T,A,missense_variant(MODERATE|MISSENSE|Act/Tct|p.Thr391Ser/c.1171A>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),2907,32,2943,"0,0108732586",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,84",Neutral,893,Tolerated,"34,12","19,81"
inspected many artifacts,UPN2_044,7,148515038,T,C,missense_variant(MODERATE|MISSENSE|Act/Gct|p.Thr391Ala/c.1171A>G|751|EZH2|protein_coding|CODING|ENST00000320356|10|C),1277,25,1312,"0,019054878",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,23",Neutral,"0,36",Tolerated,"33,85","32,28"
"low bq, low freq, many artifacts, many samples",UPN2_042,7,148515040,C,A,missense_variant(MODERATE|MISSENSE|gGg/gTg|p.Gly390Val/c.1169G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),5943,75,6033,"0,0124316261",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,87",Neutral,32,Damaging,"30,3","17,65"
"low bq, low freq, many artifacts, many samples",UPN2_043,7,148515040,C,A,missense_variant(MODERATE|MISSENSE|gGg/gTg|p.Gly390Val/c.1169G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),4792,57,4858,"0,0117332235",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,87",Neutral,32,Damaging,"29,75",14
"low bq, low freq, many artifacts, many samples",UPN2_045,7,148515040,C,A,missense_variant(MODERATE|MISSENSE|gGg/gTg|p.Gly390Val/c.1169G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),6357,87,6454,"0,0134800124",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,87",Neutral,32,Damaging,"29,98","16,71"
"low bq, low freq, many artifacts, many samples",UPN2_046,7,148515040,C,A,missense_variant(MODERATE|MISSENSE|gGg/gTg|p.Gly390Val/c.1169G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),6305,80,6396,"0,0125078174",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,87",Neutral,32,Damaging,"30,03","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_050,7,148515040,C,A,missense_variant(MODERATE|MISSENSE|gGg/gTg|p.Gly390Val/c.1169G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),6271,76,6380,"0,0119122257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,87",Neutral,32,Damaging,"30,01","16,74"
"low bq, low freq, many artifacts, many samples",UPN2_052,7,148515040,C,A,missense_variant(MODERATE|MISSENSE|gGg/gTg|p.Gly390Val/c.1169G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),5191,61,5262,"0,0115925504",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,87",Neutral,32,Damaging,"30,14","16,43"
"low bq, low freq, many artifacts, many samples",UPN2_054,7,148515040,C,A,missense_variant(MODERATE|MISSENSE|gGg/gTg|p.Gly390Val/c.1169G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),5154,61,5222,"0,0116813481",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,87",Neutral,32,Damaging,"29,87","16,38"
"low bq, low freq, many artifacts, many samples",UPN2_007,7,148515040,C,A,missense_variant(MODERATE|MISSENSE|gGg/gTg|p.Gly390Val/c.1169G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),6774,75,6853,"0,0109441121",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,87",Neutral,32,Damaging,"30,29","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_009,7,148515040,C,A,missense_variant(MODERATE|MISSENSE|gGg/gTg|p.Gly390Val/c.1169G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),7716,96,7820,"0,0122762148",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,87",Neutral,32,Damaging,"30,18","15,9"
"low bq, low freq, many artifacts, many samples",UPN2_010,7,148515040,C,A,missense_variant(MODERATE|MISSENSE|gGg/gTg|p.Gly390Val/c.1169G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),5586,69,5661,"0,0121886592",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,87",Neutral,32,Damaging,"30,12","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_055,7,148515040,C,A,missense_variant(MODERATE|MISSENSE|gGg/gTg|p.Gly390Val/c.1169G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),7240,83,7327,"0,0113279651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,87",Neutral,32,Damaging,"30,02","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_057,7,148515040,C,A,missense_variant(MODERATE|MISSENSE|gGg/gTg|p.Gly390Val/c.1169G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),6194,69,6272,"0,0110012755",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,87",Neutral,32,Damaging,"29,81","15,46"
"low bq, low freq, many artifacts, many samples",UPN2_058,7,148515040,C,A,missense_variant(MODERATE|MISSENSE|gGg/gTg|p.Gly390Val/c.1169G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),5436,66,5513,"0,0119717032",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,87",Neutral,32,Damaging,"29,97","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_059,7,148515040,C,A,missense_variant(MODERATE|MISSENSE|gGg/gTg|p.Gly390Val/c.1169G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),1714,20,1736,"0,0115207373",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,87",Neutral,32,Damaging,"30,03","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_012,7,148515040,C,A,missense_variant(MODERATE|MISSENSE|gGg/gTg|p.Gly390Val/c.1169G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),2979,39,3021,"0,0129096326",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,87",Neutral,32,Damaging,"30,05","15,77"
"low bq, low freq, many artifacts, many samples",UPN2_060,7,148515040,C,A,missense_variant(MODERATE|MISSENSE|gGg/gTg|p.Gly390Val/c.1169G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),2833,29,2867,"0,0101151029",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,87",Neutral,32,Damaging,"30,41","15,69"
"low bq, low freq, many artifacts, many samples",UPN2_066,7,148515040,C,A,missense_variant(MODERATE|MISSENSE|gGg/gTg|p.Gly390Val/c.1169G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),2813,31,2850,"0,010877193",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,87",Neutral,32,Damaging,"30,13","16,84"
"low bq, low freq, many artifacts, many samples",UPN2_067,7,148515040,C,A,missense_variant(MODERATE|MISSENSE|gGg/gTg|p.Gly390Val/c.1169G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),4128,49,4181,"0,0117196843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,87",Neutral,32,Damaging,"30,21","17,06"
"low bq, low freq, many artifacts, many samples",UPN2_073,7,148515040,C,A,missense_variant(MODERATE|MISSENSE|gGg/gTg|p.Gly390Val/c.1169G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),2439,26,2471,"0,0105220558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,87",Neutral,32,Damaging,"30,36","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_075,7,148515040,C,A,missense_variant(MODERATE|MISSENSE|gGg/gTg|p.Gly390Val/c.1169G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),4276,57,4337,"0,0131427254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,87",Neutral,32,Damaging,"30,17","17,3"
"low bq, low freq, many artifacts, many samples",UPN2_078,7,148515040,C,A,missense_variant(MODERATE|MISSENSE|gGg/gTg|p.Gly390Val/c.1169G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),3079,40,3123,"0,0128081972",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,87",Neutral,32,Damaging,"30,35","16,1"
"low bq, low freq, many artifacts, many samples",UPN2_079,7,148515040,C,A,missense_variant(MODERATE|MISSENSE|gGg/gTg|p.Gly390Val/c.1169G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),2154,31,2188,"0,0141681901",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,87",Neutral,32,Damaging,"30,15","20,68"
"low bq, low freq, many artifacts, many samples",UPN2_081,7,148515040,C,A,missense_variant(MODERATE|MISSENSE|gGg/gTg|p.Gly390Val/c.1169G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),2598,28,2627,"0,0106585459",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,87",Neutral,32,Damaging,"30,05","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_082,7,148515040,C,A,missense_variant(MODERATE|MISSENSE|gGg/gTg|p.Gly390Val/c.1169G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),4111,48,4165,"0,0115246098",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,87",Neutral,32,Damaging,"30,22","15,19"
"low bq, low freq, many artifacts",UPN2_088,7,148515040,C,A,missense_variant(MODERATE|MISSENSE|gGg/gTg|p.Gly390Val/c.1169G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),3031,39,3076,"0,0126788036",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,87",Neutral,32,Damaging,30,"16,31"
"low bq, low freq, many artifacts, many samples",UPN2_014,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),10055,130,10224,"0,01271518",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"29,07","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_015,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),15641,226,15939,"0,0141790577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"29,11","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_016,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),7692,132,7867,"0,01677895",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,78","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_017,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),5394,94,5515,"0,0170444243",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,96",14
"low bq, low freq, many artifacts, many samples",UPN2_018,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),7585,102,7732,"0,0131919296",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,98","14,07"
"low bq, low freq, many artifacts, many samples",UPN2_019,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),8455,113,8609,"0,0131257986",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"29,13","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_020,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),7162,95,7292,"0,0130279759",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,8","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_021,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),7140,102,7281,"0,0140090647",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,79","14,13"
"low bq, low freq, many artifacts, many samples",UPN2_002,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),5885,69,6007,"0,011486599",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"29,69","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_022,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),10534,126,10719,"0,0117548279",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"29,07","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_023,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),11930,157,12152,"0,012919684",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"29,35","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_024,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),5797,80,5914,"0,0135272235",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,69",14
"low bq, low freq, many artifacts, many samples",UPN2_025,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),12944,209,13231,"0,0157962361",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"29,05","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_026,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),13315,169,13557,"0,0124658848",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"29,41","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_027,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),13913,201,14193,"0,0141619108",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"29,37","14,99"
"low bq, many samples",UPN2_089,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),10598,257,10910,"0,0235563703",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,62","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_042,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),11504,204,11849,"0,0172166428",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"29,12","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_028,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),10510,131,10696,"0,0122475692",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"29,29","14,11"
"low bq, low freq, many artifacts, many samples",UPN2_043,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),9215,179,9509,"0,0188242717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,87","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_044,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),2476,39,2548,"0,0153061224",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"29,08",14
"low bq, low freq, many artifacts, many samples",UPN2_029,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),11653,160,11869,"0,0134804954",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"29,12","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_030,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),10407,166,10616,"0,0156367747",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"29,18","14,08"
"low bq, low freq, many artifacts, many samples",UPN2_031,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),6830,103,6990,"0,0147353362",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,82",14
"low bq, low freq, many artifacts, many samples",UPN2_045,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),12275,243,12685,"0,019156484",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,97","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_032,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),4325,52,4398,"0,0118235562",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"29,03",14
"low bq, low freq, many artifacts, many samples",UPN2_046,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),12119,228,12510,"0,0182254197",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"29,02","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_033,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),9324,138,9512,"0,0145079899",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,7","14,18"
"low bq, low freq, many artifacts, many samples",UPN2_034,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),3460,50,3528,"0,0141723356",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,95","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_047,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),11877,228,12290,"0,018551668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,77","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_035,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),10804,143,11013,"0,0129846545",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,74","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_036,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),7571,123,7731,"0,0159099728",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,9","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_006,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),5694,75,5807,"0,0129154469",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"29,39","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_049,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),6913,133,7176,"0,0185340022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,64","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_050,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),12077,252,12480,"0,0201923077",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,95","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_037,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),17039,234,17388,"0,0134575569",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,96","14,03"
"low bq, low freq, many artifacts, many samples",UPN2_051,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),10020,193,10358,"0,0186329407",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,81","14,1"
"low bq, low freq, many artifacts, many samples",UPN2_052,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),9977,202,10298,"0,0196154593",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"29,11","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_038,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),20569,289,20984,"0,013772398",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,99","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_039,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),7709,105,7849,"0,0133775003",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,9","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_053,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),14914,305,15401,"0,0198039088",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"29,01","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_054,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),9872,196,10214,"0,019189348",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,8","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_009,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),15096,168,15416,"0,0108977686",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"29,5","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_010,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),10954,116,11180,"0,0103756708",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"29,42",14
"low bq, low freq, many artifacts, many samples",UPN2_011,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),15259,173,15590,"0,011096857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"29,43","14,45"
"low bq, many samples",UPN2_055,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),13878,324,14385,"0,0225234619",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,86","14,52"
"low bq, many samples",UPN2_056,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),2129,50,2196,"0,0227686703",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,83",14
"low bq, many samples",UPN2_090,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),7567,183,7787,"0,0235007063",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,79","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_057,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),11882,224,12257,"0,0182752713",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,95","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_058,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),10375,226,10737,"0,0210487101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,89","14,44"
"low bq, many samples",UPN2_059,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),3184,186,3390,"0,0548672566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"27,63","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_012,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),5840,66,5956,"0,0110812626",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"29,47","14,27"
"low bq, many samples",UPN2_060,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),5277,250,5566,"0,0449155587",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"27,72","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_040,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),4582,76,4687,"0,0162150629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,74","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_013,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),3748,46,3838,"0,0119854091",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"29,56",14
"low bq, low freq, many artifacts, many samples",UPN2_091,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),7546,163,7746,"0,021043119",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,84","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_092,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),4553,100,4672,"0,0214041096",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,8","14,25"
"low bq, many samples",UPN2_093,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),5372,126,5524,"0,0228095583",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,69","15,01"
"low bq, many samples",UPN2_061,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),4661,227,4913,"0,0462039487",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"27,69","14,7"
"low bq, many samples",UPN2_062,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),3802,154,3981,"0,0386837478",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"27,42","14,58"
"low bq, many samples",UPN2_063,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),3977,194,4192,"0,046278626",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"27,73","14,81"
"low bq, many samples",UPN2_064,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),2545,129,2692,"0,0479197623",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"27,54","14,87"
"low bq, many samples",UPN2_065,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),3441,172,3629,"0,0473959769",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"27,36","14,9"
"low bq, many samples",UPN2_066,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),5229,289,5544,"0,0521284271",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"27,63","14,63"
"low bq, many samples",UPN2_067,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),7674,399,8127,"0,0490956072",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"27,33","14,84"
"low bq, many samples",UPN2_068,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),5193,253,5472,"0,0462353801",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"27,42","15,41"
"low bq, many samples",UPN2_069,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),6825,357,7247,"0,0492617635",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"27,58","14,59"
"low bq, many samples",UPN2_070,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),3799,187,4006,"0,04667998",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"27,65","15,26"
"low bq, many samples",UPN2_071,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),5477,307,5824,"0,0527129121",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"27,37","14,77"
"low bq, many samples",UPN2_072,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),4970,267,5259,"0,0507701084",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"27,51","15,43"
"low bq, many samples",UPN2_073,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),4534,264,4827,"0,0546923555",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"27,39","15,05"
"low bq, many samples",UPN2_074,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),3567,179,3779,"0,0473670283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"27,43","14,8"
"low bq, many samples",UPN2_075,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),7920,454,8427,"0,0538744512",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"27,48","15,34"
"low bq, many samples",UPN2_076,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),5471,262,5763,"0,0454624328",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"27,68",15
"low bq, many samples",UPN2_077,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),6540,325,6904,"0,0470741599",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"27,49","14,95"
"low bq, many samples",UPN2_078,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),5739,290,6069,"0,0477838194",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"27,65","14,76"
"low bq, many samples",UPN2_079,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),4025,212,4267,"0,0496836185",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"27,57","14,83"
"low bq, many samples",UPN2_080,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),4857,249,5136,"0,0484813084",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"27,43","15,11"
"low bq, many samples",UPN2_081,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),4841,241,5118,"0,0470887065",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"27,39","15,05"
"low bq, many samples",UPN2_082,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),7592,431,8080,"0,0533415842",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"27,54","14,77"
"low bq, many samples",UPN2_083,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),7160,348,7543,"0,0461354899",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"27,71","14,98"
"low bq, many samples",UPN2_084,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),6714,371,7122,"0,052092109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"27,59","15,37"
"low bq, many samples",UPN2_085,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),5660,241,5967,"0,0403888051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"27,42","15,17"
"low bq, many samples",UPN2_086,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),4272,235,4533,"0,0518420472",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"27,6","14,57"
"low bq, many samples",UPN2_087,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),8918,455,9446,"0,0481685369",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"27,56","15,02"
"low bq, many samples",UPN2_088,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),5684,287,5997,"0,047857262",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"27,33","15,05"
"low bq, many samples",UPN2_094,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),10762,251,11073,"0,0226677504",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,74","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_095,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),9453,198,9707,"0,0203976512",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,91","14,33"
"low bq, many samples",UPN2_096,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),10567,291,10912,"0,0266678886",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,71","14,53"
"low bq, many samples",UPN2_097,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),9954,266,10274,"0,0258905976",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,59","14,6"
"low bq, many samples",UPN2_098,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),9100,226,9373,"0,0241118105",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,63","14,46"
"low bq, many samples",UPN2_099,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),5381,126,5532,"0,0227765727",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,95","14,1"
"low bq, many samples",UPN2_100,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),8002,200,8241,"0,0242688994",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,53","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_101,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),8477,168,8688,"0,0193370166",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,99","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_102,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),9641,202,9894,"0,020416414",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,71","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_103,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),9316,203,9565,"0,0212232096",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,89","14,54"
"low bq, many samples",UPN2_104,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),11968,294,12316,"0,0238713868",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,77","14,6"
"low bq, many samples",UPN2_105,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),9169,244,9458,"0,025798266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,66","14,58"
"low bq, many samples",UPN2_106,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),11685,283,12041,"0,0235030313",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,69","14,64"
"low bq, many samples",UPN2_107,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),16887,386,17358,"0,022237585",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,81","14,42"
"low bq, many samples",UPN2_108,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),13840,327,14222,"0,0229925468",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,6","14,26"
"low bq, many samples",UPN2_109,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),14021,339,14432,"0,0234894678",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,81","14,59"
"low bq, many samples",UPN2_110,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),15214,362,15640,"0,0231457801",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,66","14,15"
low bq,UPN2_111,7,148515044,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala389Pro/c.1165G>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),12051,275,12381,"0,022211453",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,87,Tolerated,"28,68","14,32"
"low bq, low freq, many artifacts",UPN2_005,7,148515052,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp386Val/c.1157A>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),1838,23,1863,"0,012345679",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,91",Neutral,1,Damaging,"33,25","25,35"
"low bq, low freq, many artifacts, many samples",UPN2_016,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),7801,84,7912,"0,0106167846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,29,Damaging,"32,2","22,01"
"low bq, low freq, many artifacts, many samples",UPN2_042,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),11760,143,11952,"0,0119645248",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,29,Damaging,"31,49","18,46"
"low bq, low freq, many artifacts, many samples",UPN2_043,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),9435,121,9596,"0,0126094206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,29,Damaging,"31,48","17,51"
"low bq, low freq, many artifacts, many samples",UPN2_045,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),12533,194,12778,"0,0151823447",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,29,Damaging,"31,48","18,73"
"low bq, low freq, many artifacts, many samples",UPN2_046,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),12327,217,12635,"0,0171745152",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,29,Damaging,"31,44","22,93"
"low bq, low freq, many artifacts, many samples",UPN2_033,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),9434,100,9568,"0,010451505",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,29,Damaging,"32,18","18,05"
"low bq, low freq, many artifacts, many samples",UPN2_047,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),12194,174,12418,"0,0140119182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,29,Damaging,"31,44","21,5"
inspected many artifacts,UPN2_048,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),1213,24,1242,"0,0193236715",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,"0,029",Damaging,"31,5","27,58"
"low bq, low freq, many artifacts, many samples",UPN2_006,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),5734,75,5836,"0,012851268",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,29,Damaging,"32,46","22,79"
"low bq, low freq, many artifacts, many samples",UPN2_049,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),7100,91,7218,"0,0126073705",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,29,Damaging,"31,49","19,05"
"low bq, low freq, many artifacts, many samples",UPN2_050,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),12386,162,12599,"0,0128581633",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,29,Damaging,"31,4","18,46"
"low bq, low freq, many artifacts, many samples",UPN2_051,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),10256,133,10454,"0,0127224029",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,29,Damaging,"31,58","18,25"
"low bq, low freq, many artifacts, many samples",UPN2_052,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),10231,122,10413,"0,0117161241",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,29,Damaging,"31,47","17,22"
"low bq, low freq, many artifacts, many samples",UPN2_053,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),15238,198,15526,"0,0127528018",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,29,Damaging,"31,3","18,66"
"low bq, low freq, many artifacts, many samples",UPN2_054,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),10113,143,10303,"0,0138794526",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,29,Damaging,"31,39","18,06"
"low bq, low freq, many artifacts, many samples",UPN2_055,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),14253,201,14514,"0,0138486978",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,29,Damaging,"31,44","18,47"
"low bq, low freq, many artifacts, many samples",UPN2_056,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),2191,30,2231,"0,0134468848",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,29,Damaging,"31,54","16,97"
"low bq, low freq, many artifacts, many samples",UPN2_057,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),12171,151,12370,"0,0122069523",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,29,Damaging,"31,44","16,79"
"low bq, low freq, many artifacts, many samples",UPN2_058,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),10640,133,10837,"0,0122727692",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,29,Damaging,"31,49","16,75"
"low bq, low freq, many artifacts, many samples",UPN2_059,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),3378,43,3435,"0,0125181951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,29,Damaging,"31,01","16,79"
"low bq, low freq, many artifacts, many samples",UPN2_060,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),5519,67,5622,"0,0119174671",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,29,Damaging,"31,29","16,76"
"low bq, low freq, many artifacts, many samples",UPN2_013,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),3804,39,3863,"0,0100957805",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,29,Damaging,"32,3","17,05"
"low bq, low freq, many artifacts, many samples",UPN2_061,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),4890,59,4984,"0,0118378812",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,29,Damaging,"31,22","19,12"
"low bq, low freq, many artifacts, many samples",UPN2_063,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),4191,43,4255,"0,0101057579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,29,Damaging,"31,38","18,72"
"low bq, low freq, many artifacts, many samples",UPN2_064,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),2688,32,2740,"0,0116788321",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,29,Damaging,"31,31","19,53"
"low bq, low freq, many artifacts, many samples",UPN2_067,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),8100,97,8244,"0,0117661329",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,29,Damaging,"31,16","17,11"
"low bq, low freq, many artifacts, many samples",UPN2_068,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),5453,64,5544,"0,0115440115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,29,Damaging,"31,3","18,17"
"low bq, low freq, many artifacts, many samples",UPN2_069,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),7228,82,7355,"0,0111488783",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,29,Damaging,"31,24","20,55"
"low bq, low freq, many artifacts, many samples",UPN2_071,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),5807,71,5910,"0,0120135364",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,29,Damaging,"31,27","18,76"
"low bq, low freq, many artifacts, many samples",UPN2_072,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),5223,67,5316,"0,0126034612",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,29,Damaging,"31,14","18,39"
"low bq, low freq, many artifacts, many samples",UPN2_074,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),3756,42,3832,"0,010960334",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,29,Damaging,"31,46","17,26"
"low bq, low freq, many artifacts, many samples",UPN2_075,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),8392,101,8524,"0,0118488972",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,29,Damaging,"31,2","17,65"
"low bq, low freq, many artifacts, many samples",UPN2_077,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),6877,71,7001,"0,0101414084",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,29,Damaging,"31,39","16,8"
"low bq, low freq, many artifacts, many samples",UPN2_078,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),6057,62,6153,"0,0100763855",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,29,Damaging,"31,36","19,24"
"low bq, low freq, many artifacts, many samples",UPN2_079,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),4246,50,4314,"0,0115901715",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,29,Damaging,"31,31",19
"low bq, low freq, many artifacts, many samples",UPN2_080,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),5120,58,5203,"0,011147415",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,29,Damaging,"31,24","17,95"
"low bq, low freq, many artifacts, many samples",UPN2_081,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),5084,55,5173,"0,0106321284",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,29,Damaging,"31,4","17,09"
"low bq, low freq, many artifacts, many samples",UPN2_082,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),8046,105,8198,"0,012808002",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,29,Damaging,"31,25","18,22"
"low bq, low freq, many artifacts, many samples",UPN2_084,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),7097,88,7224,"0,0121816168",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,29,Damaging,"31,26","18,33"
"low bq, low freq, many artifacts, many samples",UPN2_085,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),5957,62,6045,"0,0102564103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,29,Damaging,"31,36","16,06"
"low bq, low freq, many artifacts, many samples",UPN2_086,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),4521,56,4602,"0,0121686223",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,29,Damaging,"31,03","18,57"
"low bq, low freq, many artifacts",UPN2_087,7,148515054,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser385Arg/c.1155T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),9403,97,9567,"0,0101390195",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,29,Damaging,"31,24","16,64"
inspected many artifacts,UPN2_056,7,148515058,T,A,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp384Val/c.1151A>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),2188,30,2233,"0,013434841",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,59",Deleterious,"0,001",Damaging,"31,51","27,8"
"low bq, low freq, many artifacts, many samples",UPN2_059,7,148515058,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp384Ala/c.1151A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),3380,37,3443,"0,0107464421",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,4,Damaging,"30,52","14,19"
"low bq, low freq, many artifacts, many samples",UPN2_061,7,148515058,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp384Ala/c.1151A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),4912,58,4992,"0,0116185897",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,4,Damaging,"30,69","14,12"
"low bq, low freq, many artifacts, many samples",UPN2_062,7,148515058,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp384Ala/c.1151A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),3958,43,4028,"0,0106752731",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,4,Damaging,"30,52","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_063,7,148515058,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp384Ala/c.1151A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),4207,44,4263,"0,0103213699",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,4,Damaging,"30,52","15,82"
"low bq, low freq, many artifacts, many samples",UPN2_064,7,148515058,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp384Ala/c.1151A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),2684,38,2745,"0,0138433515",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,4,Damaging,"30,76","17,55"
"low bq, low freq, many artifacts, many samples",UPN2_065,7,148515058,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp384Ala/c.1151A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),3622,38,3673,"0,0103457664",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,4,Damaging,"30,47","15,58"
"low bq, low freq, many artifacts, many samples",UPN2_066,7,148515058,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp384Ala/c.1151A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),5541,57,5621,"0,0101405444",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,4,Damaging,"30,54","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_068,7,148515058,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp384Ala/c.1151A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),5447,72,5553,"0,0129659643",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,4,Damaging,"30,71","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_071,7,148515058,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp384Ala/c.1151A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),5808,66,5917,"0,0111543012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,4,Damaging,"30,52","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_073,7,148515058,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp384Ala/c.1151A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),4811,61,4897,"0,0124566061",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,4,Damaging,"30,73","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_074,7,148515058,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp384Ala/c.1151A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),3778,42,3840,"0,0109375",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,4,Damaging,"30,43","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_075,7,148515058,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp384Ala/c.1151A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),8414,96,8556,"0,0112201964",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,4,Damaging,"30,61","15,65"
"low bq, low freq, many artifacts, many samples",UPN2_077,7,148515058,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp384Ala/c.1151A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),6903,74,7014,"0,0105503279",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,4,Damaging,"30,75","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_079,7,148515058,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp384Ala/c.1151A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),4252,46,4322,"0,0106432207",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,4,Damaging,"30,83","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_080,7,148515058,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp384Ala/c.1151A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),5132,53,5212,"0,0101688411",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,4,Damaging,"30,56","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_083,7,148515058,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp384Ala/c.1151A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),7540,79,7659,"0,0103146625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,4,Damaging,"30,46","14,09"
"low bq, low freq, many artifacts, many samples",UPN2_084,7,148515058,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp384Ala/c.1151A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),7134,74,7237,"0,0102252314",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,4,Damaging,"30,59","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_086,7,148515058,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp384Ala/c.1151A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),4532,54,4610,"0,0117136659",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,4,Damaging,"30,59","14,81"
"low bq, low freq, many artifacts",UPN2_087,7,148515058,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp384Ala/c.1151A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),9420,108,9583,"0,0112699572",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,4,Damaging,"30,64","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_010,7,148515065,C,A,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp382Tyr/c.1144G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),11089,113,11235,"0,0100578549",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,2,Damaging,"31,1","15,65"
"low bq, low freq, many artifacts, many samples",UPN2_086,7,148515065,C,A,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp382Tyr/c.1144G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),4540,47,4618,"0,010177566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,2,Damaging,"31,08","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_056,7,148515066,C,A,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys381Asn/c.1143G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),2202,23,2234,"0,0102954342",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,96",Neutral,161,Tolerated,"30,51","18,04"
inspected many artifacts,UPN2_056,7,148515071,A,G,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser380Pro/c.1138T>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),2190,30,2233,"0,013434841",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,"0,06",Tolerated,"32,5","31,63"
"low bq, low freq, many artifacts, many samples",UPN2_064,7,148515071,A,T,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser380Thr/c.1138T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),2718,29,2750,"0,0105454545",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,489,Tolerated,"30,64","26,9"
"low bq, low freq, many artifacts, many samples",UPN2_049,7,148515076,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu378Gln/c.1133T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),7135,74,7242,"0,0102181718",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,14",Neutral,"0,56",Tolerated,"31,65","19,07"
"low bq, low freq, many artifacts",UPN2_053,7,148515076,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu378Gln/c.1133T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),15309,161,15565,"0,0103437199",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,14",Neutral,"0,56",Tolerated,"31,63","21,68"
"low bq, low freq, many artifacts, many samples",UPN2_043,7,148515079,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val377Glu/c.1130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),9472,102,9618,"0,0106051154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,6",Neutral,984,Tolerated,"31,64","20,18"
"low bq, low freq, many artifacts, many samples",UPN2_044,7,148515079,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val377Glu/c.1130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),2562,30,2602,"0,0115295926",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,6",Neutral,984,Tolerated,"31,83","17,47"
"low bq, low freq, many artifacts, many samples",UPN2_047,7,148515079,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val377Glu/c.1130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),12232,153,12444,"0,012295082",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,6",Neutral,984,Tolerated,"31,65","19,29"
"low bq, low freq, many artifacts, many samples",UPN2_049,7,148515079,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val377Glu/c.1130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),7129,73,7241,"0,0100814805",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,6",Neutral,984,Tolerated,"31,62","17,99"
"low bq, low freq, many artifacts, many samples",UPN2_051,7,148515079,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val377Glu/c.1130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),10323,112,10485,"0,0106819266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,6",Neutral,984,Tolerated,"31,75","19,51"
"low bq, low freq, many artifacts, many samples",UPN2_052,7,148515079,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val377Glu/c.1130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),10289,116,10439,"0,0111121755",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,6",Neutral,984,Tolerated,"31,84","18,77"
"low bq, low freq, many artifacts, many samples",UPN2_056,7,148515079,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val377Glu/c.1130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),2201,27,2233,"0,0120913569",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,6",Neutral,984,Tolerated,"31,46","21,26"
"low bq, low freq, many artifacts, many samples",UPN2_057,7,148515079,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val377Glu/c.1130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),12225,134,12407,"0,0108003546",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,6",Neutral,984,Tolerated,"31,72","18,78"
"low bq, low freq, many artifacts, many samples",UPN2_064,7,148515079,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val377Glu/c.1130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),2703,30,2752,"0,0109011628",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,6",Neutral,984,Tolerated,"31,77",21
"low bq, low freq, many artifacts",UPN2_086,7,148515079,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val377Glu/c.1130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),4539,58,4619,"0,0125568305",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,6",Neutral,984,Tolerated,"31,87","22,43"
"low bq, low freq, many artifacts, many samples",UPN2_044,7,148515081,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn376Lys/c.1128T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),2562,29,2601,"0,0111495579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,41",Neutral,"0,19",Tolerated,"32,36","16,9"
"low bq, low freq, many artifacts, many samples",UPN2_045,7,148515081,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn376Lys/c.1128T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),12617,154,12810,"0,0120218579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,41",Neutral,"0,19",Tolerated,"32,29","22,49"
"low bq, low freq, many artifacts, many samples",UPN2_049,7,148515081,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn376Lys/c.1128T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),7107,109,7243,"0,0150490128",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,41",Neutral,"0,19",Tolerated,"32,22","20,58"
"low bq, low freq, many artifacts, many samples",UPN2_050,7,148515081,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn376Lys/c.1128T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),12446,129,12641,"0,0102048889",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,41",Neutral,"0,19",Tolerated,"32,41","16,74"
"low bq, low freq, many artifacts, many samples",UPN2_055,7,148515081,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn376Lys/c.1128T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),14310,157,14552,"0,010788895",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,41",Neutral,"0,19",Tolerated,"32,2","17,51"
"low bq, low freq, many artifacts",UPN2_076,7,148515081,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn376Lys/c.1128T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),5789,63,5863,"0,0107453522",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,41",Neutral,"0,19",Tolerated,"31,41","22,75"
"low bq, low freq, many artifacts, many samples",UPN2_042,7,148515085,A,T,missense_variant(MODERATE|MISSENSE|aTt/aAt|p.Ile375Asn/c.1124T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),11793,125,11975,"0,0104384134",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,493,Tolerated,"32,14","17,18"
"low bq, low freq, many artifacts, many samples",UPN2_043,7,148515085,A,T,missense_variant(MODERATE|MISSENSE|aTt/aAt|p.Ile375Asn/c.1124T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),9449,125,9620,"0,012993763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,493,Tolerated,"32,13","18,63"
"low bq, low freq, many artifacts, many samples",UPN2_044,7,148515085,A,T,missense_variant(MODERATE|MISSENSE|aTt/aAt|p.Ile375Asn/c.1124T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),2555,27,2600,"0,0103846154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,493,Tolerated,"32,02","17,59"
"low bq, low freq, many artifacts, many samples",UPN2_045,7,148515085,A,T,missense_variant(MODERATE|MISSENSE|aTt/aAt|p.Ile375Asn/c.1124T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),12613,136,12809,"0,0106175345",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,493,Tolerated,"32,02","16,61"
"low bq, low freq, many artifacts, many samples",UPN2_046,7,148515085,A,T,missense_variant(MODERATE|MISSENSE|aTt/aAt|p.Ile375Asn/c.1124T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),12457,145,12668,"0,0114461636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,493,Tolerated,"32,2","17,34"
"low bq, low freq, many artifacts, many samples",UPN2_047,7,148515085,A,T,missense_variant(MODERATE|MISSENSE|aTt/aAt|p.Ile375Asn/c.1124T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),12260,128,12440,"0,0102893891",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,493,Tolerated,"32,12","16,8"
"low bq, low freq, many artifacts, many samples",UPN2_049,7,148515085,A,T,missense_variant(MODERATE|MISSENSE|aTt/aAt|p.Ile375Asn/c.1124T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),7106,76,7243,"0,0104928897",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,493,Tolerated,"31,94","15,5"
"low bq, low freq, many artifacts, many samples",UPN2_050,7,148515085,A,T,missense_variant(MODERATE|MISSENSE|aTt/aAt|p.Ile375Asn/c.1124T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),12451,138,12645,"0,0109134045",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,493,Tolerated,"32,03","16,07"
"low bq, low freq, many artifacts, many samples",UPN2_051,7,148515085,A,T,missense_variant(MODERATE|MISSENSE|aTt/aAt|p.Ile375Asn/c.1124T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),10300,134,10496,"0,0127667683",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,493,Tolerated,"32,08","16,35"
"low bq, low freq, many artifacts, many samples",UPN2_052,7,148515085,A,T,missense_variant(MODERATE|MISSENSE|aTt/aAt|p.Ile375Asn/c.1124T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),10283,119,10441,"0,0113973757",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,493,Tolerated,"32,18","15,52"
"low bq, low freq, many artifacts, many samples",UPN2_053,7,148515085,A,T,missense_variant(MODERATE|MISSENSE|aTt/aAt|p.Ile375Asn/c.1124T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),15330,167,15568,"0,0107271326",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,493,Tolerated,"32,01","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_056,7,148515085,A,T,missense_variant(MODERATE|MISSENSE|aTt/aAt|p.Ile375Asn/c.1124T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),2199,25,2237,"0,0111756817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,493,Tolerated,"32,04","16,04"
"low bq, low freq, many artifacts, many samples",UPN2_057,7,148515085,A,T,missense_variant(MODERATE|MISSENSE|aTt/aAt|p.Ile375Asn/c.1124T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),12197,130,12413,"0,0104728913",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,493,Tolerated,"32,1","16,12"
"low bq, low freq, many artifacts",UPN2_058,7,148515085,A,T,missense_variant(MODERATE|MISSENSE|aTt/aAt|p.Ile375Asn/c.1124T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),10708,117,10873,"0,0107605997",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,493,Tolerated,"32,11",16
"low bq, low freq, many artifacts, many samples",UPN2_014,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),10037,164,10234,"0,0160250147",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,39","18,95"
"low bq, low freq, many artifacts, many samples",UPN2_015,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),15541,290,15912,"0,0182252388",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,23","17,31"
"low bq, low freq, many artifacts, many samples",UPN2_016,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),7707,113,7867,"0,0143637981",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,56","16,84"
"low bq, low freq, many artifacts, many samples",UPN2_017,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),5404,101,5516,"0,0183103698",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,2","18,79"
"low bq, low freq, many artifacts, many samples",UPN2_018,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),7551,149,7737,"0,0192581104",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,48","18,25"
"low bq, low freq, many artifacts, many samples",UPN2_019,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),8415,162,8608,"0,0188197026",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,11","17,53"
"low bq, low freq, many artifacts, many samples",UPN2_020,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),7138,109,7280,"0,0149725275",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,52","16,48"
"low bq, low freq, many artifacts, many samples",UPN2_021,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),7128,116,7279,"0,015936255",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,48","17,74"
"low bq, low freq, many artifacts, many samples",UPN2_022,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),10506,185,10735,"0,0172333489",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,36","17,63"
"low bq, low freq, many artifacts, many samples",UPN2_023,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),11863,216,12136,"0,0177982861",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,23","17,3"
"low bq, low freq, many artifacts, many samples",UPN2_024,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),5772,110,5906,"0,018625127",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,45","17,61"
"low bq, low freq, many artifacts, many samples",UPN2_025,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),12999,193,13251,"0,0145649385",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,33","16,45"
"low bq, low freq, many artifacts, many samples",UPN2_026,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),13269,218,13558,"0,0160790677",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,03","17,23"
"low bq, low freq, many artifacts, many samples",UPN2_027,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),13840,255,14159,"0,0180097465",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,13","16,89"
"low bq, low freq, many artifacts, many samples",UPN2_042,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),11718,143,11918,"0,0119986575",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"28,05","17,31"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_028,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),10458,193,10698,"0,0180407553",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"26,95","18,64"
"low bq, low freq, many artifacts, many samples",UPN2_043,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),9388,136,9577,"0,0142006892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"28,22","16,93"
"low bq, low freq, many artifacts, many samples",UPN2_044,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),2538,30,2581,"0,0116234018",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"28,11",17
"low bq, low freq, many artifacts, many samples",UPN2_029,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),11619,214,11875,"0,0180210526",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,36","17,56"
"low bq, low freq, many artifacts, many samples",UPN2_030,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),10414,192,10644,"0,0180383315",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,21","16,94"
"low bq, low freq, many artifacts, many samples",UPN2_031,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),6840,128,6998,"0,0182909403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,53","17,96"
"low bq, low freq, many artifacts, many samples",UPN2_045,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),12521,149,12751,"0,011685358",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"28,04","17,46"
"low bq, low freq, many artifacts, many samples",UPN2_032,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),4296,66,4374,"0,0150891632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,13","15,83"
"low bq, low freq, many artifacts, many samples",UPN2_046,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),12343,176,12573,"0,0139982502",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"28,21","17,32"
"low bq, low freq, many artifacts, many samples",UPN2_033,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),9334,126,9512,"0,0132464256",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,59","15,97"
"low bq, low freq, many artifacts, many samples",UPN2_034,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),3441,58,3524,"0,0164585698",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,48","17,14"
"low bq, low freq, many artifacts, many samples",UPN2_047,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),12176,162,12376,"0,0130898513",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"28,27","19,35"
"low bq, low freq, many artifacts, many samples",UPN2_035,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),10678,220,10967,"0,0200601805",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,43","17,19"
"low bq, low freq, many artifacts, many samples",UPN2_036,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),7548,125,7705,"0,0162232317",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,11","17,32"
"low bq, low freq, many artifacts, many samples",UPN2_049,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),7084,88,7214,"0,0121985029",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"28,2","18,93"
"low bq, low freq, many artifacts, many samples",UPN2_050,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),12406,132,12599,"0,010477022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"28,06","17,47"
"low bq, low freq, many artifacts, many samples",UPN2_037,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),16974,336,17361,"0,0193537239",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,15","17,6"
"low bq, low freq, many artifacts, many samples",UPN2_052,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),10199,124,10378,"0,0119483523",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"28,13","17,67"
"low bq, low freq, many artifacts, many samples",UPN2_038,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),20546,359,21007,"0,0170895416",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,39","18,33"
"low bq, low freq, many artifacts, many samples",UPN2_039,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),7650,153,7836,"0,019525268",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,1","17,77"
"low bq, low freq, many artifacts, many samples",UPN2_053,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),15211,205,15491,"0,0132334904",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"28,12","18,18"
"low bq, low freq, many artifacts, many samples",UPN2_054,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),10047,138,10247,"0,0134673563",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"28,09","18,11"
"low bq, low freq, many artifacts, many samples",UPN2_007,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),13287,145,13497,"0,0107431281",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"28,88","19,28"
"low bq, low freq, many artifacts, many samples",UPN2_008,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),17090,179,17339,"0,0103235481",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"28,65","17,08"
"low bq, low freq, many artifacts, many samples",UPN2_010,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),11005,127,11175,"0,0113646532",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"28,68","20,17"
"low bq, low freq, many artifacts, many samples",UPN2_055,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),14205,201,14467,"0,0138936891",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"28,06","18,77"
"low bq, low freq, many artifacts, many samples",UPN2_057,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),12124,136,12315,"0,011043443",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"28,12","16,07"
"low bq, low freq, many artifacts, many samples",UPN2_058,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),10650,141,10831,"0,0130181885",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"28,23","18,82"
"low bq, low freq, many artifacts, many samples",UPN2_059,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),3352,68,3433,"0,0198077483",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,4","16,81"
"low bq, low freq, many artifacts, many samples",UPN2_012,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),5869,76,5977,"0,0127154091",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"28,83","20,53"
"low bq, low freq, many artifacts, many samples",UPN2_060,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),5478,104,5608,"0,0185449358",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,35","16,64"
"low bq, low freq, many artifacts, many samples",UPN2_040,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),4596,79,4688,"0,0168515358",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,52","17,09"
"low bq, low freq, many artifacts, many samples",UPN2_013,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),3783,43,3844,"0,0111862643",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"28,53","19,79"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),4852,90,4966,"0,018123238",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"26,89","16,52"
"low bq, low freq, many artifacts, many samples",UPN2_062,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),3908,82,4013,"0,0204335908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,01","16,41"
"low bq, low freq, many artifacts, many samples",UPN2_063,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),4129,89,4242,"0,0209806695",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,25","16,69"
"low bq, many samples",UPN2_064,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),2639,69,2737,"0,025210084",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,12","17,91"
"low bq, many samples",UPN2_065,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),3560,84,3662,"0,0229382851",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,21","17,62"
"low bq, low freq, many artifacts, many samples",UPN2_066,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),5456,119,5599,"0,0212537953",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,2","18,08"
"low bq, low freq, many artifacts, many samples",UPN2_067,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),8033,136,8203,"0,0165793003",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,54","17,1"
"low bq, low freq, many artifacts, many samples",UPN2_068,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),5433,100,5551,"0,0180147721",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,13","16,65"
"low bq, low freq, many artifacts, many samples",UPN2_069,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),7166,131,7328,"0,0178766376",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,36","15,57"
"low bq, low freq, many artifacts, many samples",UPN2_070,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),3945,89,4058,"0,0219319862",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,18","16,22"
"low bq, low freq, many artifacts, many samples",UPN2_071,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),5742,120,5883,"0,0203977562",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,15","16,06"
"low bq, low freq, many artifacts, many samples",UPN2_072,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),5179,102,5303,"0,0192343956",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,06","16,51"
"low bq, low freq, many artifacts, many samples",UPN2_073,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),4761,103,4881,"0,0211022331",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,43","16,57"
"low bq, low freq, many artifacts, many samples",UPN2_074,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),3748,55,3819,"0,0144016758",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,34","15,98"
"low bq, low freq, many artifacts, many samples",UPN2_075,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),8333,148,8514,"0,0173831337",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,36","17,17"
"low bq, many samples",UPN2_076,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),5640,148,5809,"0,025477707",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,26","17,25"
"low bq, low freq, many artifacts, many samples",UPN2_077,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),6832,123,6983,"0,0176142059",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,07","16,72"
"low bq, low freq, many artifacts, many samples",UPN2_078,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),5980,123,6126,"0,0200783546",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,07","16,77"
"low bq, low freq, many artifacts, many samples",UPN2_079,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),4187,83,4291,"0,0193428105",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,09","17,96"
"low bq, low freq, many artifacts, many samples",UPN2_080,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),5086,92,5208,"0,0176651306",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,23","16,39"
"low bq, low freq, many artifacts, many samples",UPN2_081,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),5032,100,5160,"0,019379845",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,2","16,03"
"low bq, low freq, many artifacts, many samples",UPN2_082,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),8008,151,8189,"0,0184393699",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,37","16,85"
"low bq, many samples",UPN2_083,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),7400,169,7605,"0,0222222222",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,01","16,29"
"low bq, low freq, many artifacts, many samples",UPN2_084,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),7013,157,7200,"0,0218055556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,15","15,62"
"low bq, low freq, many artifacts, many samples",UPN2_085,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),5898,111,6032,"0,0184018568",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,15","16,77"
"low bq, low freq, many artifacts, many samples",UPN2_086,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),4487,88,4586,"0,0191888356",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,25","16,09"
"low bq, low freq, many artifacts, many samples",UPN2_087,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),9336,195,9565,"0,020386827",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,37","16,83"
"low bq, low freq, many artifacts",UPN2_088,7,148515089,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr374Pro/c.1120A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),5896,119,6041,"0,0196987254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,104,Tolerated,"27,16","17,18"
inspected,UPN2_099,7,148515089,TG,T,frameshift_variant(HIGH||ccc/|p.Thr374fs/c.1119delC|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),2842,31,2883,"0,0107526882",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,82",NA
"low bq, low freq, many artifacts",UPN2_070,7,148515091,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro373His/c.1118C>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),2014,22,2039,"0,0107896027",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,15,Damaging,"32,73","16,32"
"low bq, low freq, many artifacts, many samples",UPN2_059,7,148515095,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr372Pro/c.1114A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),1696,24,1725,"0,0139130435",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,69,Tolerated,"28,73",14
"low bq, low freq, many artifacts, many samples",UPN2_060,7,148515095,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr372Pro/c.1114A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),2736,47,2798,"0,0167977127",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,69,Tolerated,"28,28","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_061,7,148515095,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr372Pro/c.1114A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),2451,26,2491,"0,0104375753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,69,Tolerated,"28,59","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_062,7,148515095,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr372Pro/c.1114A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),1970,26,2005,"0,012967581",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,69,Tolerated,"28,42","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_063,7,148515095,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr372Pro/c.1114A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),2092,22,2124,"0,0103578154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,69,Tolerated,"28,55","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_064,7,148515095,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr372Pro/c.1114A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),1341,22,1366,"0,0161054173",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,69,Tolerated,"28,82","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_065,7,148515095,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr372Pro/c.1114A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),1807,20,1834,"0,0109051254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,69,Tolerated,"28,67","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_066,7,148515095,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr372Pro/c.1114A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),2770,34,2808,"0,0121082621",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,69,Tolerated,"28,8","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_067,7,148515095,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr372Pro/c.1114A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),4041,54,4115,"0,0131227217",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,69,Tolerated,"28,95","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_068,7,148515095,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr372Pro/c.1114A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),2720,39,2767,"0,0140946874",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,69,Tolerated,"28,67","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_069,7,148515095,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr372Pro/c.1114A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),3611,41,3667,"0,0111808017",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,69,Tolerated,"28,89","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_070,7,148515095,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr372Pro/c.1114A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),1996,25,2026,"0,0123395854",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,69,Tolerated,"28,54","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_071,7,148515095,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr372Pro/c.1114A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),2895,30,2943,"0,0101936799",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,69,Tolerated,"28,61","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_072,7,148515095,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr372Pro/c.1114A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),2597,35,2655,"0,0131826742",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,69,Tolerated,"28,76","14,2"
"low bq, low freq, many artifacts, many samples",UPN2_073,7,148515095,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr372Pro/c.1114A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),2410,25,2449,"0,0102082483",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,69,Tolerated,"28,92",14
"low bq, low freq, many artifacts, many samples",UPN2_075,7,148515095,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr372Pro/c.1114A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),4201,44,4255,"0,0103407756",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,69,Tolerated,"28,81","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_076,7,148515095,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr372Pro/c.1114A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),2874,32,2921,"0,0109551523",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,69,Tolerated,"28,45","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_078,7,148515095,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr372Pro/c.1114A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),3029,33,3069,"0,0107526882",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,69,Tolerated,"28,37","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_079,7,148515095,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr372Pro/c.1114A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),2121,28,2155,"0,0129930394",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,69,Tolerated,"28,67","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_081,7,148515095,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr372Pro/c.1114A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),2542,28,2581,"0,0108485083",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,69,Tolerated,"28,93","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_083,7,148515095,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr372Pro/c.1114A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),3733,54,3811,"0,0141695093",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,69,Tolerated,"28,19","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_084,7,148515095,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr372Pro/c.1114A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),3538,53,3606,"0,014697726",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,69,Tolerated,"28,51","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_085,7,148515095,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr372Pro/c.1114A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),2969,33,3014,"0,0109489051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,69,Tolerated,"28,8",14
"low bq, low freq, many artifacts, many samples",UPN2_086,7,148515095,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr372Pro/c.1114A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),2247,35,2295,"0,0152505447",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,69,Tolerated,"28,62","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_087,7,148515095,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr372Pro/c.1114A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),4702,53,4777,"0,0110948294",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,69,Tolerated,"29,11","15,74"
"low bq, low freq, many artifacts",UPN2_088,7,148515095,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr372Pro/c.1114A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),2982,35,3032,"0,0115435356",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,69,Tolerated,"28,52","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_068,7,148515098,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser371Arg/c.1111A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),2724,28,2768,"0,0101156069",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,"0,05",Damaging,"30,15","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_074,7,148515098,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser371Arg/c.1111A>C|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),1880,22,1912,"0,0115062762",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,"0,05",Damaging,"30,11","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_042,7,148515108,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser367Arg/c.1101T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),5900,63,5982,"0,0105315948",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,117,Tolerated,"33,83","18,9"
"low bq, low freq, many artifacts, many samples",UPN2_043,7,148515108,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser367Arg/c.1101T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),4707,67,4793,"0,013978719",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,117,Tolerated,"33,91","17,87"
"low bq, low freq, many artifacts, many samples",UPN2_045,7,148515108,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser367Arg/c.1101T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),6299,78,6400,"0,0121875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,117,Tolerated,"33,71","17,88"
"low bq, low freq, many artifacts, many samples",UPN2_046,7,148515108,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser367Arg/c.1101T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),6234,70,6317,"0,0110812094",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,117,Tolerated,"33,73","16,99"
"low bq, low freq, many artifacts, many samples",UPN2_047,7,148515108,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser367Arg/c.1101T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),6125,66,6208,"0,0106314433",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,117,Tolerated,"33,82","16,32"
"low bq, low freq, many artifacts, many samples",UPN2_049,7,148515108,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser367Arg/c.1101T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),3557,45,3612,"0,0124584718",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,117,Tolerated,"33,62","19,89"
"low bq, low freq, many artifacts, many samples",UPN2_050,7,148515108,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser367Arg/c.1101T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),6193,84,6312,"0,0133079848",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,117,Tolerated,"33,67","18,88"
"low bq, low freq, many artifacts, many samples",UPN2_051,7,148515108,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser367Arg/c.1101T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),5159,67,5236,"0,0127960275",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,117,Tolerated,"33,72","16,85"
"low bq, low freq, many artifacts, many samples",UPN2_052,7,148515108,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser367Arg/c.1101T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),5132,61,5215,"0,0116970278",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,117,Tolerated,"33,72","17,52"
"low bq, low freq, many artifacts, many samples",UPN2_053,7,148515108,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser367Arg/c.1101T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),7638,82,7752,"0,0105779154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,117,Tolerated,"33,64","17,41"
"low bq, low freq, many artifacts, many samples",UPN2_054,7,148515108,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser367Arg/c.1101T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),5055,72,5143,"0,0139996111",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,117,Tolerated,"33,83","18,01"
"low bq, low freq, many artifacts, many samples",UPN2_055,7,148515108,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser367Arg/c.1101T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),7159,73,7261,"0,0100537116",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,117,Tolerated,"33,63",19
"low bq, low freq, many artifacts, many samples",UPN2_057,7,148515108,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser367Arg/c.1101T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),6092,76,6188,"0,0122818358",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,117,Tolerated,"33,71","17,03"
"low bq, low freq, many artifacts, many samples",UPN2_058,7,148515108,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser367Arg/c.1101T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),5326,69,5422,"0,0127259314",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,117,Tolerated,"33,7","16,96"
"low bq, low freq, many artifacts, many samples",UPN2_092,7,148515108,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser367Arg/c.1101T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),2309,26,2346,"0,0110826939",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,117,Tolerated,"34,79","25,12"
"low bq, low freq, many artifacts",UPN2_078,7,148515108,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser367Arg/c.1101T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),3033,35,3073,"0,0113895216",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,117,Tolerated,"33,75","19,57"
"low bq, low freq, many artifacts, many samples",UPN2_001,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),2268,34,2306,"0,0147441457",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,19","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_014,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),5052,61,5129,"0,0118931566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,7","15,89"
"low bq, low freq, many artifacts, many samples",UPN2_015,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),7870,100,7990,"0,0125156446",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,8","15,89"
"low bq, low freq, many artifacts, many samples",UPN2_016,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),3893,40,3947,"0,0101342792",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,66","16,2"
"low bq, low freq, many artifacts, many samples",UPN2_017,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),2725,33,2767,"0,0119262739",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,76",16
"low bq, low freq, many artifacts, many samples",UPN2_019,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),4272,45,4326,"0,0104022191",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,88","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_020,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),3608,48,3662,"0,0131075915",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,91","16,56"
"low bq, low freq, many artifacts, many samples",UPN2_002,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),2944,61,3011,"0,0202590501",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"31,99","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_022,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),5293,75,5383,"0,0139327513",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,77","16,89"
"low bq, low freq, many artifacts, many samples",UPN2_023,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),6015,67,6105,"0,010974611",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,66","16,04"
"low bq, low freq, many artifacts, many samples",UPN2_024,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),2928,31,2964,"0,0104588394",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,74","16,58"
"low bq, low freq, many artifacts, many samples",UPN2_025,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),6557,76,6646,"0,0114354499",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,69","17,34"
"low bq, low freq, many artifacts, many samples",UPN2_026,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),6698,88,6802,"0,0129373714",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,59","16,81"
"low bq, low freq, many artifacts, many samples",UPN2_027,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),6990,107,7111,"0,0150471101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,75","16,08"
"low bq, low freq, many artifacts, many samples",UPN2_042,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),5848,105,5982,"0,017552658",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"31,94","16,18"
"low bq, low freq, many artifacts, many samples",UPN2_028,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),5278,71,5368,"0,0132265276",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,52","16,31"
"low bq, low freq, many artifacts, many samples",UPN2_043,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),4681,95,4794,"0,0198164372",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"31,97","16,26"
"low bq, many samples",UPN2_044,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),1259,32,1296,"0,024691358",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,35","17,44"
"low bq, low freq, many artifacts, many samples",UPN2_029,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),5844,82,5946,"0,0137907837",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,77","15,84"
"low bq, low freq, many artifacts, many samples",UPN2_030,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),5248,66,5325,"0,0123943662",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,78","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_031,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),3440,53,3505,"0,0151212553",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,85","17,77"
"low bq, low freq, many artifacts, many samples",UPN2_045,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),6260,120,6401,"0,0187470708",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"31,95","17,1"
"low bq, low freq, many artifacts, many samples",UPN2_032,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),2175,24,2203,"0,0108942351",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,97","17,79"
"low bq, low freq, many artifacts, many samples",UPN2_046,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),6177,128,6318,"0,0202595758",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"31,99","15,62"
"low bq, low freq, many artifacts, many samples",UPN2_033,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),4678,74,4766,"0,0155266471",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,91","16,81"
"low bq, low freq, many artifacts, many samples",UPN2_034,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),1732,23,1766,"0,0130237826",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,51","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_047,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),6060,126,6210,"0,0202898551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,1","15,72"
"low bq, low freq, many artifacts, many samples",UPN2_035,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),5405,91,5519,"0,0164884943",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,82","16,78"
"low bq, low freq, many artifacts, many samples",UPN2_036,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),3823,51,3879,"0,0131477185",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,78","16,94"
"low bq, low freq, many artifacts, many samples",UPN2_006,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),2890,49,2943,"0,0166496772",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,3","16,51"
"low bq, many samples",UPN2_049,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),3515,83,3612,"0,022978959",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"31,82","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_050,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),6171,119,6312,"0,0188529785",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"31,82","15,72"
"low bq, low freq, many artifacts, many samples",UPN2_037,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),8603,92,8715,"0,0105565118",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,82","17,59"
"low bq, many samples",UPN2_051,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),5094,126,5238,"0,0240549828",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,32,"18,06"
"low bq, many samples",UPN2_052,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),5077,125,5216,"0,0239647239",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,09","15,51"
"low bq, low freq, many artifacts, many samples",UPN2_038,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),10382,128,10540,"0,0121442125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,92","15,83"
"low bq, low freq, many artifacts, many samples",UPN2_039,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),3895,40,3945,"0,010139417",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,56","17,38"
"low bq, low freq, many artifacts, many samples",UPN2_053,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),7562,158,7752,"0,0203818369",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"31,83","15,99"
"low bq, low freq, many artifacts, many samples",UPN2_054,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),5022,101,5144,"0,0196345257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"31,98","15,3"
"low bq, low freq, many artifacts, many samples",UPN2_007,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),6636,118,6776,"0,0174144038",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,07","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_008,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),8553,135,8704,"0,0155101103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,19","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_009,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),7597,120,7737,"0,0155098876",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,11","15,82"
"low bq, low freq, many artifacts, many samples",UPN2_010,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),5494,86,5598,"0,0153626295",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,13","16,22"
"low bq, low freq, many artifacts, many samples",UPN2_011,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),7690,117,7832,"0,014938713",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,22","16,25"
"low bq, low freq, many artifacts, many samples",UPN2_055,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),7082,151,7261,"0,0207960336",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"31,93","16,6"
"low bq, many samples",UPN2_056,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),1086,29,1117,"0,0259623993",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"31,98",17
"low bq, many samples",UPN2_057,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),6013,156,6189,"0,0252060107",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,04","18,57"
"low bq, low freq, many artifacts, many samples",UPN2_058,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),5287,118,5423,"0,0217591739",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"31,94","16,83"
"low bq, low freq, many artifacts, many samples",UPN2_059,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),1686,31,1725,"0,0179710145",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,27","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_012,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),2931,53,2992,"0,0177139037",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,27","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_060,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),2758,34,2801,"0,012138522",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,28","16,35"
"low bq, low freq, many artifacts, many samples",UPN2_040,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),2307,34,2351,"0,0144619311",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,33,"17,65"
"low bq, low freq, many artifacts, many samples",UPN2_013,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),1881,42,1930,"0,021761658",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"31,79","15,48"
"low bq, low freq, many artifacts, many samples",UPN2_061,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),2450,29,2492,"0,0116372392",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"31,69","15,52"
"low bq, low freq, many artifacts, many samples",UPN2_065,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),1802,27,1833,"0,0147299509",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,46",14
"low bq, low freq, many artifacts, many samples",UPN2_066,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),2759,39,2810,"0,0138790036",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,11","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_067,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),4044,57,4116,"0,0138483965",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,04","15,74"
"low bq, low freq, many artifacts, many samples",UPN2_068,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),2717,40,2768,"0,0144508671",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,47","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_069,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),3616,41,3669,"0,011174707",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,29","15,39"
"low bq, low freq, many artifacts, many samples",UPN2_070,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),1986,30,2026,"0,0148075025",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,11","15,17"
"low bq, low freq, many artifacts, many samples",UPN2_071,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),2896,39,2945,"0,0132427844",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,33","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_072,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),2614,33,2657,"0,0124200226",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,15","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_073,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),2406,33,2448,"0,0134803922",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,3","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_074,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),1884,20,1913,"0,0104547831",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,18","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_075,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),4188,59,4261,"0,0138465149",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,32","16,75"
"low bq, low freq, many artifacts, many samples",UPN2_076,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),2866,40,2921,"0,0136939404",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,19","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_077,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),3455,36,3501,"0,0102827763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,38","16,08"
"low bq, low freq, many artifacts, many samples",UPN2_079,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),2123,23,2155,"0,0106728538",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,32","15,52"
"low bq, low freq, many artifacts, many samples",UPN2_080,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),2568,30,2604,"0,0115207373",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,41","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_081,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),2542,33,2582,"0,0127807901",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,27","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_082,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),4015,46,4077,"0,011282806",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,43","16,7"
"low bq, low freq, many artifacts, many samples",UPN2_083,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),3756,39,3812,"0,0102308499",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,15","15,31"
"low bq, low freq, many artifacts, many samples",UPN2_085,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),2958,41,3015,"0,0135986733",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,23","15,41"
"low bq, low freq, many artifacts, many samples",UPN2_086,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),2251,29,2295,"0,0126361656",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,06","15,83"
"low bq, low freq, many artifacts",UPN2_088,7,148515114,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn365Lys/c.1095T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),2979,44,3035,"0,0144975288",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,69",Neutral,967,Tolerated,"32,3","14,3"
"low bq, low freq, many artifacts",UPN2_049,7,148515121,A,T,missense_variant(MODERATE|MISSENSE|cTt/cAt|p.Leu363His/c.1088T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),3555,38,3613,"0,0105175754",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,51",Neutral,143,Tolerated,"33,74","19,13"
"Not in 2nd Illumina, many artifacts, low freq",UPN2_006,7,148515163,T,C,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys349Arg/c.1046A>G|751|EZH2|protein_coding|CODING|ENST00000320356|10|C),7143,79,7251,"0,010895049",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,83",Neutral,"0,107",Tolerated,"35,29","35,05"
"inspected, many artifacts, strandbias",UPN2_044,7,148515187,GC,G,frameshift_variant(HIGH||gct/|p.Ala341fs/c.1021delG|751|EZH2|protein_coding|CODING|ENST00000320356|10|G),3071,74,3156,"0,0234474018",0,0,0,1,1,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,15",NA
"low freq, many artifacts",UPN2_044,7,148515194,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe339Ile/c.1015T>A|751|EZH2|protein_coding|CODING|ENST00000320356|10|T),3094,40,3151,"0,0126943827",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,365,Tolerated,"32,44","27,95"
"low freq, many artifacts",UPN2_044,7,148515195,C,A,missense_variant(MODERATE|MISSENSE|gaG/gaT|p.Glu338Asp/c.1014G>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),1857,32,1892,"0,0169133192",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,9,Damaging,"35,5","30,88"
"low bq, low freq, many artifacts",UPN2_046,7,148515200,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys337*/c.1009A>T|751|EZH2|protein_coding|CODING|ENST00000320356|10|A),12019,134,12206,"0,0109782074",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,28","23,25"
inspected many artifacts,UPN2_044,7,148516737,T,C,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu317Gly/c.950A>G|751|EZH2|protein_coding|CODING|ENST00000320356|9|C),1818,20,1842,"0,0108577633",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,"0,022",Damaging,"35,2","35,05"
inspected many artifacts,UPN2_044,7,148516746,T,C,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys314Arg/c.941A>G|751|EZH2|protein_coding|CODING|ENST00000320356|9|C),1816,23,1842,"0,0124864278",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,225",Tolerated,"34,8","32,65"
"low freq, many artifacts",UPN2_006,7,148516749,C,T,missense_variant(MODERATE|MISSENSE|cGg/cAg|p.Arg313Gln/c.938G>A|751|EZH2|protein_coding|CODING|ENST00000320356|9|T),4679,48,4741,"0,0101244463",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,9,Damaging,"33,77","34,46"
inspected many artifacts,UPN2_097,7,148516754,A,T,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr311*/c.933T>A|751|EZH2|protein_coding|CODING|ENST00000320356|9|T),3604,41,3650,"0,0112328767",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,07","35,15"
"Not in 2nd Illumina, many artifacts, low freq",UPN2_006,7,148516765,G,A,missense_variant(MODERATE|MISSENSE|Ccc/Tcc|p.Pro308Ser/c.922C>T|751|EZH2|protein_coding|CODING|ENST00000320356|9|A),4668,65,4739,"0,0137159738",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,7",Deleterious,"0,002",Damaging,"34,96","35,8"
"Not in 2nd Illumina, many artifacts, low freq",UPN2_001,7,148516778,A,G,splice_region_variant+synonymous_variant(LOW|SILENT|tcT/tcC|p.Ser303Ser/c.909T>C|751|EZH2|protein_coding|CODING|ENST00000320356|9|G),7967,91,8083,"0,0112581962",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,0,Neutral,"0,226",Tolerated,"31,77","30,16"
"low freq, many artifacts, many samples",UPN2_014,7,148516778,A,G,splice_region_variant+synonymous_variant(LOW|SILENT|tcT/tcC|p.Ser303Ser/c.909T>C|751|EZH2|protein_coding|CODING|ENST00000320356|9|G),12230,178,12447,"0,0143006347",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,0,Neutral,226,Tolerated,"31,74","27,76"
"low freq, many artifacts, many samples",UPN2_042,7,148516778,A,G,splice_region_variant+synonymous_variant(LOW|SILENT|tcT/tcC|p.Ser303Ser/c.909T>C|751|EZH2|protein_coding|CODING|ENST00000320356|9|G),10972,150,11171,"0,0134276251",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,0,Neutral,226,Tolerated,"30,49","28,53"
"low freq, many artifacts, many samples",UPN2_028,7,148516778,A,G,splice_region_variant+synonymous_variant(LOW|SILENT|tcT/tcC|p.Ser303Ser/c.909T>C|751|EZH2|protein_coding|CODING|ENST00000320356|9|G),14000,178,14211,"0,0125255084",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,0,Neutral,226,Tolerated,"31,77","27,85"
"low freq, many artifacts, many samples",UPN2_046,7,148516778,A,G,splice_region_variant+synonymous_variant(LOW|SILENT|tcT/tcC|p.Ser303Ser/c.909T>C|751|EZH2|protein_coding|CODING|ENST00000320356|9|G),16953,216,17247,"0,0125239172",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,0,Neutral,226,Tolerated,"30,46","28,71"
"low freq, many artifacts, many samples",UPN2_051,7,148516778,A,G,splice_region_variant+synonymous_variant(LOW|SILENT|tcT/tcC|p.Ser303Ser/c.909T>C|751|EZH2|protein_coding|CODING|ENST00000320356|9|G),14070,184,14333,"0,0128375078",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,0,Neutral,226,Tolerated,"30,57","28,02"
"low freq, many artifacts, many samples",UPN2_008,7,148516778,A,G,splice_region_variant+synonymous_variant(LOW|SILENT|tcT/tcC|p.Ser303Ser/c.909T>C|751|EZH2|protein_coding|CODING|ENST00000320356|9|G),26304,267,26642,"0,0100217701",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,0,Neutral,226,Tolerated,"31,74","30,86"
"low freq, many artifacts, many samples",UPN2_055,7,148516778,A,G,splice_region_variant+synonymous_variant(LOW|SILENT|tcT/tcC|p.Ser303Ser/c.909T>C|751|EZH2|protein_coding|CODING|ENST00000320356|9|G),15445,197,15714,"0,0125365916",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,0,Neutral,226,Tolerated,"30,46","28,6"
"low freq, many artifacts, many samples",UPN2_057,7,148516778,A,G,splice_region_variant+synonymous_variant(LOW|SILENT|tcT/tcC|p.Ser303Ser/c.909T>C|751|EZH2|protein_coding|CODING|ENST00000320356|9|G),18160,291,18541,"0,0156949463",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,0,Neutral,226,Tolerated,"30,43","28,26"
"low freq, many artifacts",UPN2_058,7,148516778,A,G,splice_region_variant+synonymous_variant(LOW|SILENT|tcT/tcC|p.Ser303Ser/c.909T>C|751|EZH2|protein_coding|CODING|ENST00000320356|9|G),16540,208,16820,"0,0123662307",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,0,Neutral,226,Tolerated,"30,4","27,93"
inspected many artifacts,UPN2_044,7,148523561,G,A,missense_variant(MODERATE|MISSENSE|Cgt/Tgt|p.Arg298Cys/c.892C>T|751|EZH2|protein_coding|CODING|ENST00000320356|8|A),1985,45,2036,"0,0221021611",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,83",Deleterious,"0,001",Damaging,"35,08","35,33"
"Sanger other sample; inspected, many artifacts, low freq",UPN2_044,7,148523591,G,A,stop_gained(HIGH|NONSENSE|Cga/Tga|p.Arg288*/c.862C>T|751|EZH2|protein_coding|CODING|ENST00000320356|8|A),3949,46,4018,"0,0114484818",0,0,0,0,1,0,0,1,2,NO,NO,COSM1000721,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,19","30,76"
"low freq, many artifacts, many samples",UPN2_016,7,148523602,A,G,missense_variant(MODERATE|MISSENSE|cTt/cCt|p.Leu284Pro/c.851T>C|751|EZH2|protein_coding|CODING|ENST00000320356|8|G),16877,185,17151,"0,0107865431",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,93",Deleterious,0,Damaging,"32,93","33,44"
"low freq, many artifacts, many samples",UPN2_017,7,148523602,A,G,missense_variant(MODERATE|MISSENSE|cTt/cCt|p.Leu284Pro/c.851T>C|751|EZH2|protein_coding|CODING|ENST00000320356|8|G),10579,125,10752,"0,011625744",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,93",Deleterious,0,Damaging,"32,73","33,08"
"low freq, many artifacts, many samples",UPN2_042,7,148523602,A,G,missense_variant(MODERATE|MISSENSE|cTt/cCt|p.Leu284Pro/c.851T>C|751|EZH2|protein_coding|CODING|ENST00000320356|8|G),19951,212,20309,"0,0104387217",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,93",Deleterious,0,Damaging,"32,17","31,72"
"low freq, many artifacts, many samples",UPN2_028,7,148523602,A,G,missense_variant(MODERATE|MISSENSE|cTt/cCt|p.Leu284Pro/c.851T>C|751|EZH2|protein_coding|CODING|ENST00000320356|8|G),24671,266,25034,"0,0106255493",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,93",Deleterious,0,Damaging,"32,66","33,33"
"inspected, low freq, many artifacts, many samples",UPN2_043,7,148523602,A,G,missense_variant(MODERATE|MISSENSE|cTt/cCt|p.Leu284Pro/c.851T>C|751|EZH2|protein_coding|CODING|ENST00000320356|8|G),25062,291,25548,"0,0113903241",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,93",Deleterious,0,Damaging,"32,14","32,43"
"inspected, low freq, many artifacts, many samples",UPN2_045,7,148523602,A,G,missense_variant(MODERATE|MISSENSE|cTt/cCt|p.Leu284Pro/c.851T>C|751|EZH2|protein_coding|CODING|ENST00000320356|8|G),26532,322,27028,"0,0119135711",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,93",Deleterious,0,Damaging,"32,03","32,05"
"inspected, low freq, many artifacts, many samples",UPN2_032,7,148523602,A,G,missense_variant(MODERATE|MISSENSE|cTt/cCt|p.Leu284Pro/c.851T>C|751|EZH2|protein_coding|CODING|ENST00000320356|8|G),10823,165,11034,"0,0149537792",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,93",Deleterious,0,Damaging,"32,74","32,98"
"inspected, low freq, many artifacts, many samples",UPN2_036,7,148523602,A,G,missense_variant(MODERATE|MISSENSE|cTt/cCt|p.Leu284Pro/c.851T>C|751|EZH2|protein_coding|CODING|ENST00000320356|8|G),31679,323,32137,"0,0100507204",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,93",Deleterious,0,Damaging,"32,76","32,97"
"inspected, low freq, many artifacts, many samples",UPN2_049,7,148523602,A,G,missense_variant(MODERATE|MISSENSE|cTt/cCt|p.Leu284Pro/c.851T>C|751|EZH2|protein_coding|CODING|ENST00000320356|8|G),16563,175,16859,"0,0103802123",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,93",Deleterious,0,Damaging,"32,05","32,46"
"inspected, low freq, many artifacts, many samples",UPN2_050,7,148523602,A,G,missense_variant(MODERATE|MISSENSE|cTt/cCt|p.Leu284Pro/c.851T>C|751|EZH2|protein_coding|CODING|ENST00000320356|8|G),32429,368,33034,"0,0111400375",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,93",Deleterious,0,Damaging,"32,07","32,33"
"inspected, low freq, many artifacts, many samples",UPN2_037,7,148523602,A,G,missense_variant(MODERATE|MISSENSE|cTt/cCt|p.Leu284Pro/c.851T>C|751|EZH2|protein_coding|CODING|ENST00000320356|8|G),36755,376,37277,"0,0100866486",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,93",Deleterious,0,Damaging,"32,71","33,09"
"inspected, low freq, many artifacts, many samples",UPN2_051,7,148523602,A,G,missense_variant(MODERATE|MISSENSE|cTt/cCt|p.Leu284Pro/c.851T>C|751|EZH2|protein_coding|CODING|ENST00000320356|8|G),29839,351,30411,"0,0115418763",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,93",Deleterious,0,Damaging,"32,13","32,25"
"inspected, low freq, many artifacts, many samples",UPN2_052,7,148523602,A,G,missense_variant(MODERATE|MISSENSE|cTt/cCt|p.Leu284Pro/c.851T>C|751|EZH2|protein_coding|CODING|ENST00000320356|8|G),29111,317,29657,"0,0106888762",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,93",Deleterious,0,Damaging,"32,02","32,57"
"inspected, low freq, many artifacts, many samples",UPN2_053,7,148523602,A,G,missense_variant(MODERATE|MISSENSE|cTt/cCt|p.Leu284Pro/c.851T>C|751|EZH2|protein_coding|CODING|ENST00000320356|8|G),38468,442,39197,"0,0112763732",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,93",Deleterious,0,Damaging,"32,01","32,03"
"inspected, low freq, many artifacts, many samples",UPN2_055,7,148523602,A,G,missense_variant(MODERATE|MISSENSE|cTt/cCt|p.Leu284Pro/c.851T>C|751|EZH2|protein_coding|CODING|ENST00000320356|8|G),35899,399,36557,"0,0109144623",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,93",Deleterious,0,Damaging,"32,07","32,77"
"inspected, low freq, many artifacts, many samples",UPN2_057,7,148523602,A,G,missense_variant(MODERATE|MISSENSE|cTt/cCt|p.Leu284Pro/c.851T>C|751|EZH2|protein_coding|CODING|ENST00000320356|8|G),37799,498,38539,"0,0129219751",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,93",Deleterious,0,Damaging,"31,96","32,59"
"inspected, low freq, many artifacts, many samples",UPN2_092,7,148523602,A,G,missense_variant(MODERATE|MISSENSE|cTt/cCt|p.Leu284Pro/c.851T>C|751|EZH2|protein_coding|CODING|ENST00000320356|8|G),11392,139,11561,"0,0120231814",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,93",Deleterious,0,Damaging,"32,84","32,09"
"inspected, low freq, many artifacts, many samples",UPN2_074,7,148523602,A,G,missense_variant(MODERATE|MISSENSE|cTt/cCt|p.Leu284Pro/c.851T>C|751|EZH2|protein_coding|CODING|ENST00000320356|8|G),20840,221,21184,"0,0104324018",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,93",Deleterious,0,Damaging,"31,47","31,5"
"inspected, low freq, many artifacts, many samples",UPN2_095,7,148523602,A,G,missense_variant(MODERATE|MISSENSE|cTt/cCt|p.Leu284Pro/c.851T>C|751|EZH2|protein_coding|CODING|ENST00000320356|8|G),18526,189,18779,"0,0100644337",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,93",Deleterious,0,Damaging,"32,84","31,87"
"inspected, low freq, many artifacts, many samples",UPN2_109,7,148523602,A,G,missense_variant(MODERATE|MISSENSE|cTt/cCt|p.Leu284Pro/c.851T>C|751|EZH2|protein_coding|CODING|ENST00000320356|8|G),27955,291,28335,"0,0102699841",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,93",Deleterious,0,Damaging,"32,74","32,01"
"inspected, many artifacts",UPN2_056,7,148523616,G,T,missense_variant(MODERATE|MISSENSE|caC/caA|p.His279Gln/c.837C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),2139,36,2178,"0,0165289256",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,92",Deleterious,"0,017",Damaging,"33,74","31,78"
"low freq, many artifacts",UPN2_056,7,148523617,T,C,missense_variant(MODERATE|MISSENSE|cAc/cGc|p.His279Arg/c.836A>G|751|EZH2|protein_coding|CODING|ENST00000320356|8|C),2145,22,2179,"0,0100963745",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,92",Deleterious,1,Damaging,"32,44","31,45"
"inspected, many artifacts",UPN2_056,7,148523658,A,T,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp265Glu/c.795T>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),2113,52,2174,"0,0239190432",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,"0,068",Tolerated,"32,33","30,25"
"low bq, low freq, many artifacts, many samples",UPN2_001,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),17894,227,18144,"0,0125110229",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"32,02","16,11"
"low bq, low freq, many artifacts, many samples",UPN2_016,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),16849,188,17063,"0,0110179921",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"31,76","16,24"
"low bq, low freq, many artifacts, many samples",UPN2_002,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),21768,231,22033,"0,0104842736",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"32,11","15,74"
"low bq, low freq, many artifacts, many samples",UPN2_003,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),4408,55,4472,"0,0122987478",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"32,08","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_024,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),12394,139,12547,"0,0110783454",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"31,7","15,4"
"low bq, low freq, many artifacts, many samples",UPN2_042,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),19982,303,20320,"0,0149114173",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"30,69","16,12"
"low bq, low freq, many artifacts, many samples",UPN2_043,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),25060,375,25483,"0,0147156928",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"30,78",16
"low bq, low freq, many artifacts, many samples",UPN2_044,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),3916,53,3970,"0,0133501259",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"30,81","16,43"
"low bq, low freq, many artifacts, many samples",UPN2_029,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),28312,322,28659,"0,011235563",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"31,82","16,12"
"low bq, low freq, many artifacts, many samples",UPN2_005,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),6202,70,6278,"0,0111500478",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"31,97","17,6"
"low bq, low freq, many artifacts, many samples",UPN2_045,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),26557,365,26985,"0,013526033",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"30,76","15,85"
"low bq, low freq, many artifacts, many samples",UPN2_046,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),35037,507,35609,"0,0142379735",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"30,76","16,35"
"low bq, low freq, many artifacts, many samples",UPN2_047,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),22145,369,22548,"0,0163650878",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"30,8","16,22"
"low bq, low freq, many artifacts, many samples",UPN2_036,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),31621,332,31991,"0,0103779188",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"31,78","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_006,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),16949,174,17139,"0,0101522843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"32,14","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_049,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),16615,212,16848,"0,0125830959",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"30,74","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_050,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),32405,517,33004,"0,0156647679",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"30,71","16,1"
"low bq, low freq, many artifacts, many samples",UPN2_051,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),29805,472,30330,"0,0155621497",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"30,8","16,27"
"low bq, low freq, many artifacts, many samples",UPN2_052,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),29021,446,29535,"0,0151007279",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"30,85","15,96"
"low bq, low freq, many artifacts, many samples",UPN2_038,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),46062,500,46625,"0,0107238606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"31,82","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_053,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),38467,547,39065,"0,0140023039",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"30,73","16,16"
"low bq, low freq, many artifacts, many samples",UPN2_054,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),28590,421,29074,"0,0144802917",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"30,83","15,8"
"low bq, low freq, many artifacts, many samples",UPN2_007,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),48556,644,49267,"0,0130716301",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"31,96","15,7"
"low bq, low freq, many artifacts, many samples",UPN2_008,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),62282,676,63050,"0,0107216495",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"32,07","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_009,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),46432,595,47052,"0,0126455836",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"32,03","15,42"
"low bq, low freq, many artifacts, many samples",UPN2_011,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),49214,688,49938,"0,0137770836",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"32,04","17,38"
"low bq, low freq, many artifacts, many samples",UPN2_055,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),35924,492,36491,"0,0134827766",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"30,81","15,54"
"inspected, many artifacts",UPN2_056,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),2051,99,2151,"0,0460251046",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,"0,003",Damaging,"30,67","26,29"
"low bq, low freq, many artifacts, many samples",UPN2_057,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),37753,590,38418,"0,0153573846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"30,75","15,58"
"low bq, low freq, many artifacts, many samples",UPN2_058,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),35982,565,36602,"0,015436315",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"30,71","16,66"
"low bq, low freq, many artifacts, many samples",UPN2_059,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),8640,89,8744,"0,0101784081",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"31,14","16,03"
"low bq, low freq, many artifacts, many samples",UPN2_012,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),21842,258,22126,"0,0116604899",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"32,04","15,59"
"low bq, low freq, many artifacts, many samples",UPN2_060,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),29557,346,29967,"0,011546034",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"31,09","15,31"
"low bq, low freq, many artifacts, many samples",UPN2_040,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),17538,182,17748,"0,0102546766",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"31,77","15,61"
"low bq, low freq, many artifacts, many samples",UPN2_013,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),13785,162,13976,"0,0115912994",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"32,04","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_061,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),22394,261,22679,"0,0115084439",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"31,15",15
"low bq, low freq, many artifacts, many samples",UPN2_063,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),22978,240,23252,"0,0103216928",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"31,14","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_065,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),16592,179,16802,"0,0106534936",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"31,05","16,02"
"low bq, low freq, many artifacts, many samples",UPN2_066,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),36882,435,37361,"0,0116431573",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"31,11","15,71"
"low bq, low freq, many artifacts, many samples",UPN2_067,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),41203,494,41758,"0,0118300685",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"31,17","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_069,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),36350,402,36800,"0,010923913",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"31,14","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_070,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),22943,235,23220,"0,0101205857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"31,15","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_071,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),21339,251,21621,"0,0116090838",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"31,07","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_072,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),20452,229,20716,"0,0110542576",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"31,12","15,41"
"low bq, low freq, many artifacts, many samples",UPN2_073,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),15847,191,16056,"0,0118958645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"31,16","15,57"
"low bq, low freq, many artifacts, many samples",UPN2_074,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),20820,259,21105,"0,0122719735",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"31,18","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_075,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),36073,423,36547,"0,0115741374",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"31,13","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_077,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),33207,349,33608,"0,0103844323",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"31,17","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_078,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),26382,289,26739,"0,0108081828",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"31,14","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_079,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),20083,232,20335,"0,0114089009",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"31,09","15,4"
"low bq, low freq, many artifacts, many samples",UPN2_080,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),24990,288,25319,"0,0113748568",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"31,17","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_081,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),14056,168,14257,"0,0117836852",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"31,09","15,72"
"low bq, low freq, many artifacts, many samples",UPN2_082,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),39104,435,39603,"0,0109840164",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"31,06","15,55"
"low bq, low freq, many artifacts, many samples",UPN2_085,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),34354,357,34759,"0,0102707213",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"31,16","15,64"
"low bq, low freq, many artifacts, many samples",UPN2_086,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),23744,267,24058,"0,0110981794",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"31,13","15,25"
"low bq, low freq, many artifacts, many samples",UPN2_087,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),42349,462,42870,"0,010776767",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"31,1","15,4"
"low bq, low freq, many artifacts",UPN2_088,7,148523664,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn263Lys/c.789C>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),32920,365,33338,"0,0109484672",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,3,Damaging,"31,09","15,17"
"low bq, low freq, many artifacts",UPN2_042,7,148523675,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys260Ser/c.778T>A|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),9972,118,10134,"0,0116439708",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,57",Deleterious,2,Damaging,"34,56","23,56"
"low freq, many artifacts",UPN2_044,7,148523688,TG,T,frameshift_variant(HIGH||gca/|p.Ala255fs/c.764delC|751|EZH2|protein_coding|CODING|ENST00000320356|8|T),4539,55,4600,"0,0119565217",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,36",NA
"bad alignment, many artifacts",UPN2_048,7,148523719,T,C,missense_variant(MODERATE|MISSENSE|aAa/aGa|p.Lys245Arg/c.734A>G|751|EZH2|protein_coding|CODING|ENST00000320356|8|C),2421,25,2457,"0,0101750102",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,3",Neutral,"0,693",Tolerated,"35,2","35,12"
"bad alignment, many artifacts",UPN2_048,7,148523722,T,C,missense_variant(MODERATE|MISSENSE|tAt/tGt|p.Tyr244Cys/c.731A>G|751|EZH2|protein_coding|CODING|ENST00000320356|8|C),2410,44,2457,"0,0179080179",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,48",Deleterious,"0,001",Damaging,"35,13",35
"inspected, many artifacts",UPN2_044,7,148524256,T,C,missense_variant(MODERATE|MISSENSE|aAa/aGa|p.Lys243Arg/c.728A>G|751|EZH2|protein_coding|CODING|ENST00000320356|7|C),1980,32,2015,"0,0158808933",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,"0,545",Tolerated,"35,21","34,97"
"many samples, many artifacts",UPN2_045,7,148524256,T,C,missense_variant(MODERATE|MISSENSE|aAa/aGa|p.Lys243Arg/c.728A>G|751|EZH2|protein_coding|CODING|ENST00000320356|7|C),4629,48,4702,"0,0102084219",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,"0,545",Tolerated,"35,3","34,67"
"many samples, many artifacts",UPN2_046,7,148524256,T,C,missense_variant(MODERATE|MISSENSE|aAa/aGa|p.Lys243Arg/c.728A>G|751|EZH2|protein_coding|CODING|ENST00000320356|7|C),8830,90,8957,"0,0100480071",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,"0,545",Tolerated,"35,22","34,18"
"inspected, many artifacts",UPN2_052,7,148524256,T,C,missense_variant(MODERATE|MISSENSE|aAa/aGa|p.Lys243Arg/c.728A>G|751|EZH2|protein_coding|CODING|ENST00000320356|7|C),7058,78,7164,"0,0108877722",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,"0,545",Tolerated,"35,22","34,33"
"many samples, many artifacts",UPN2_053,7,148524256,T,C,missense_variant(MODERATE|MISSENSE|aAa/aGa|p.Lys243Arg/c.728A>G|751|EZH2|protein_coding|CODING|ENST00000320356|7|C),12403,141,12578,"0,0112100493",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,"0,545",Tolerated,"35,24","33,92"
"low freq, many artifacts, many samples",UPN2_058,7,148524256,T,C,missense_variant(MODERATE|MISSENSE|aAa/aGa|p.Lys243Arg/c.728A>G|751|EZH2|protein_coding|CODING|ENST00000320356|7|C),11891,124,12037,"0,0103015702",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,545,Tolerated,"35,26","33,15"
"low freq, many artifacts, many samples",UPN2_070,7,148524256,T,C,missense_variant(MODERATE|MISSENSE|aAa/aGa|p.Lys243Arg/c.728A>G|751|EZH2|protein_coding|CODING|ENST00000320356|7|C),4416,45,4469,"0,0100693667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,545,Tolerated,"35,22","35,91"
"many samples, many artifacts",UPN2_082,7,148524256,T,C,missense_variant(MODERATE|MISSENSE|aAa/aGa|p.Lys243Arg/c.728A>G|751|EZH2|protein_coding|CODING|ENST00000320356|7|C),2847,32,2885,"0,0110918544",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,"0,545",Tolerated,"35,17","33,97"
"many samples, many artifacts",UPN2_088,7,148524256,T,C,missense_variant(MODERATE|MISSENSE|aAa/aGa|p.Lys243Arg/c.728A>G|751|EZH2|protein_coding|CODING|ENST00000320356|7|C),5806,63,5886,"0,0107033639",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,"0,545",Tolerated,"35,32","35,33"
"many artifacts, bad alignment",UPN2_044,7,148524262,T,C,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys241Arg/c.722A>G|751|EZH2|protein_coding|CODING|ENST00000320356|7|C),1981,23,2014,"0,0114200596",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,"0,321",Tolerated,"35,15","34,35"
inspected,UPN2_049,7,148524266,G,T,missense_variant(MODERATE|MISSENSE|Cta/Ata|p.Leu240Ile/c.718C>A|751|EZH2|protein_coding|CODING|ENST00000320356|7|T),849,23,872,"0,0263761468",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,7",Neutral,"0,139",Tolerated,"35,3","35,35"
"many artifacts, bad alignment",UPN2_006,7,148524277,G,T,missense_variant(MODERATE|MISSENSE|aCa/aAa|p.Thr236Lys/c.707C>A|751|EZH2|protein_coding|CODING|ENST00000320356|7|T),2550,58,2615,"0,0221797323",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,7",Deleterious,"0,06",Tolerated,"35,14","34,45"
"many artifacts, bad alignment",UPN2_006,7,148524283,T,C,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys234Arg/c.701A>G|751|EZH2|protein_coding|CODING|ENST00000320356|7|C),2560,46,2615,"0,0175908222",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,"0,052",Tolerated,"34,62","35,3"
"many artifacts, bad alignment",UPN2_006,7,148524286,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp233Val/c.698A>T|751|EZH2|protein_coding|CODING|ENST00000320356|7|A),2577,34,2615,"0,013001912",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,53",Deleterious,0,Damaging,"35,14","34,47"
"many artifacts, bad alignment",UPN2_044,7,148524287,C,T,missense_variant(MODERATE|MISSENSE|Gat/Aat|p.Asp233Asn/c.697G>A|751|EZH2|protein_coding|CODING|ENST00000320356|7|T),1939,70,2015,"0,0347394541",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,68",Deleterious,"0,094",Tolerated,"35,15","35,11"
"low bq, low freq, many artifacts, many samples",UPN2_042,7,148524304,A,T,missense_variant(MODERATE|MISSENSE|aTt/aAt|p.Ile227Asn/c.680T>A|751|EZH2|protein_coding|CODING|ENST00000320356|7|T),2021,21,2062,"0,0101842871",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,56",Deleterious,0,Damaging,"31,68","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_043,7,148524304,A,T,missense_variant(MODERATE|MISSENSE|aTt/aAt|p.Ile227Asn/c.680T>A|751|EZH2|protein_coding|CODING|ENST00000320356|7|T),8540,90,8674,"0,0103758358",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,56",Deleterious,0,Damaging,"31,65","17,82"
"low bq, low freq, many artifacts",UPN2_044,7,148524304,A,T,missense_variant(MODERATE|MISSENSE|aTt/aAt|p.Ile227Asn/c.680T>A|751|EZH2|protein_coding|CODING|ENST00000320356|7|T),3848,44,3908,"0,011258956",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,56",Deleterious,0,Damaging,"31,51","16,39"
"low bq, low freq, many artifacts",UPN2_065,7,148524307,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala226Asp/c.677C>A|751|EZH2|protein_coding|CODING|ENST00000320356|7|T),2040,22,2064,"0,0106589147",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,0,Damaging,"30,18",14
"inspected, many artifacts",UPN2_042,7,148524308,C,T,missense_variant(MODERATE|MISSENSE|Gcc/Acc|p.Ala226Thr/c.676G>A|751|EZH2|protein_coding|CODING|ENST00000320356|7|T),2040,28,2073,"0,0135069947",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,"0,001",Damaging,"31,9","30,96"
"many artifacts, bad alignment",UPN2_044,7,148524319,T,A,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys222Ile/c.665A>T|751|EZH2|protein_coding|CODING|ENST00000320356|7|A),3880,84,3976,"0,0211267606",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,"0,486",Tolerated,"32,04","31,39"
"low freq, many artifacts",UPN2_078,7,148524326,A,G,missense_variant(MODERATE|MISSENSE|Tct/Cct|p.Ser220Pro/c.658T>C|751|EZH2|protein_coding|CODING|ENST00000320356|7|G),9518,101,9672,"0,0104425145",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,4",Neutral,"0,08",Tolerated,"33,92","33,62"
"low freq, many artifacts",UPN2_044,7,148524342,TG,T,frameshift_variant(HIGH||cca/|p.Pro214fs/c.641delC|751|EZH2|protein_coding|CODING|ENST00000320356|7|T),3905,40,3979,"0,0100527771",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,18",NA
"low bq, low freq, many artifacts",UPN2_075,7,148524343,G,T,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro214Gln/c.641C>A|751|EZH2|protein_coding|CODING|ENST00000320356|7|T),11225,128,11404,"0,0112241319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,14",Neutral,38,Damaging,"30,91","14,8"
"low bq, low freq, many artifacts",UPN2_088,7,148524346,C,A,missense_variant(MODERATE|MISSENSE|cGc/cTc|p.Arg213Leu/c.638G>T|751|EZH2|protein_coding|CODING|ENST00000320356|7|A),11510,118,11665,"0,0101157308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,2",Neutral,258,Tolerated,"29,48","15,12"
"inspected, complex indel, not easy SNV",UPN2_098,7,148525847,C,A,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu204*/c.610G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),5266,997,6286,"0,158606427",1,1,0,1,0,0,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,65","35,72"
"low freq, many artifacts",UPN2_044,7,148525849,A,G,missense_variant(MODERATE|MISSENSE|cTg/cCg|p.Leu203Pro/c.608T>C|751|EZH2|protein_coding|CODING|ENST00000320356|6|G),3109,39,3156,"0,0123574144",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,68",Neutral,"0,188",Tolerated,"35,61","35,33"
"low freq, many artifacts",UPN2_022,7,148525861,T,C,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys199Arg/c.596A>G|751|EZH2|protein_coding|CODING|ENST00000320356|6|C),6890,70,6977,"0,0100329655",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,36",Neutral,"0,05",Damaging,"34,92","33,54"
"low freq, many artifacts",UPN2_024,7,148525861,T,C,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys199Arg/c.596A>G|751|EZH2|protein_coding|CODING|ENST00000320356|6|C),3557,37,3605,"0,0102635229",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,36",Neutral,"0,05",Damaging,"34,95","34,43"
"low freq, many artifacts",UPN2_045,7,148525861,T,C,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys199Arg/c.596A>G|751|EZH2|protein_coding|CODING|ENST00000320356|6|C),9531,101,9664,"0,0104511589",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,36",Neutral,"0,05",Damaging,"34,91","33,31"
"low freq, many artifacts",UPN2_032,7,148525861,T,C,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys199Arg/c.596A>G|751|EZH2|protein_coding|CODING|ENST00000320356|6|C),2853,33,2890,"0,0114186851",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,36",Neutral,"0,05",Damaging,"35,01","35,33"
"low freq, many artifacts",UPN2_051,7,148525861,T,C,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys199Arg/c.596A>G|751|EZH2|protein_coding|CODING|ENST00000320356|6|C),7540,82,7648,"0,0107217573",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,36",Neutral,"0,05",Damaging,"34,98","34,15"
"low freq, many artifacts",UPN2_055,7,148525861,T,C,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys199Arg/c.596A>G|751|EZH2|protein_coding|CODING|ENST00000320356|6|C),10575,110,10707,"0,0102736528",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,36",Neutral,"0,05",Damaging,"34,98","34,66"
"low freq, many artifacts",UPN2_056,7,148525861,T,C,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys199Arg/c.596A>G|751|EZH2|protein_coding|CODING|ENST00000320356|6|C),1704,21,1730,"0,0121387283",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,36",Neutral,"0,05",Damaging,"34,97","33,62"
"low freq, many artifacts",UPN2_044,7,148525884,G,T,missense_variant(MODERATE|MISSENSE|gaC/gaA|p.Asp191Glu/c.573C>A|751|EZH2|protein_coding|CODING|ENST00000320356|6|T),3109,39,3155,"0,0123613312",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,45",Neutral,"0,258",Tolerated,"34,03","32,64"
"low freq, many artifacts",UPN2_012,7,148525888,CCAT,C,disruptive_inframe_deletion(MODERATE||gatgga/gga|p.Asp189del/c.566_568delATG|751|EZH2|protein_coding|CODING|ENST00000320356|6|C),5242,59,5347,"0,0110342248",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,"-2,07",Neutral,NA,NA,"34,08",NA
"SNP, low freq",UPN2_094,7,148525904,C,G,missense_variant(MODERATE|MISSENSE|Gac/Cac|p.Asp185His/c.553G>C|751|EZH2|protein_coding|CODING|ENST00000320356|6|G),5137,267,5413,"0,0493256974",0,0,0,0,1,0,0,1,2,NO,NO,COSM3762469,"soft_tissue, thyroid","3, 1",rs2302427,rs2302427,NO,NO,NO,YES,"-2,4",Neutral,"0,005",Damaging,"34,54","34,51"
"low freq, many artifacts",UPN2_006,7,148525924,A,T,missense_variant(MODERATE|MISSENSE|cTt/cAt|p.Leu178His/c.533T>A|751|EZH2|protein_coding|CODING|ENST00000320356|6|T),10694,146,10897,"0,013398183",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,22",Deleterious,0,Damaging,"33,63","31,87"
"low bq, low freq, many artifacts, many samples",UPN2_059,7,148525927,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala177Asp/c.530C>A|751|EZH2|protein_coding|CODING|ENST00000320356|6|T),22318,267,22637,"0,0117948491",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,8,Damaging,"28,72","15,31"
"low bq, low freq, many artifacts, many samples",UPN2_061,7,148525927,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala177Asp/c.530C>A|751|EZH2|protein_coding|CODING|ENST00000320356|6|T),26495,305,26858,"0,0113560206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,8,Damaging,"28,75","15,66"
"low bq, low freq, many artifacts, many samples",UPN2_062,7,148525927,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala177Asp/c.530C>A|751|EZH2|protein_coding|CODING|ENST00000320356|6|T),22843,264,23192,"0,0113832356",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,8,Damaging,"28,72","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_063,7,148525927,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala177Asp/c.530C>A|751|EZH2|protein_coding|CODING|ENST00000320356|6|T),23488,251,23805,"0,0105440034",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,8,Damaging,"28,76","15,45"
"low bq, low freq, many artifacts, many samples",UPN2_064,7,148525927,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala177Asp/c.530C>A|751|EZH2|protein_coding|CODING|ENST00000320356|6|T),20202,209,20459,"0,0102155531",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,8,Damaging,"28,83","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_065,7,148525927,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala177Asp/c.530C>A|751|EZH2|protein_coding|CODING|ENST00000320356|6|T),27978,316,28361,"0,0111420613",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,8,Damaging,"28,71","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_066,7,148525927,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala177Asp/c.530C>A|751|EZH2|protein_coding|CODING|ENST00000320356|6|T),54536,585,55258,"0,0105867024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,8,Damaging,"28,76","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_067,7,148525927,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala177Asp/c.530C>A|751|EZH2|protein_coding|CODING|ENST00000320356|6|T),55417,597,56217,"0,0106195635",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,8,Damaging,"28,66","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_068,7,148525927,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala177Asp/c.530C>A|751|EZH2|protein_coding|CODING|ENST00000320356|6|T),33333,338,33759,"0,0100121449",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,8,Damaging,"28,78","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_069,7,148525927,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala177Asp/c.530C>A|751|EZH2|protein_coding|CODING|ENST00000320356|6|T),32201,341,32652,"0,0104434644",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,8,Damaging,"28,68","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_071,7,148525927,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala177Asp/c.530C>A|751|EZH2|protein_coding|CODING|ENST00000320356|6|T),17677,188,17920,"0,0104910714",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,8,Damaging,"28,63","15,77"
"low bq, low freq, many artifacts, many samples",UPN2_073,7,148525927,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala177Asp/c.530C>A|751|EZH2|protein_coding|CODING|ENST00000320356|6|T),17010,185,17230,"0,0107370865",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,8,Damaging,"28,68","15,5"
"low bq, low freq, many artifacts, many samples",UPN2_074,7,148525927,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala177Asp/c.530C>A|751|EZH2|protein_coding|CODING|ENST00000320356|6|T),22149,267,22474,"0,0118803951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,8,Damaging,"28,71","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_075,7,148525927,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala177Asp/c.530C>A|751|EZH2|protein_coding|CODING|ENST00000320356|6|T),30336,313,30727,"0,0101864809",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,8,Damaging,"28,76","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_076,7,148525927,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala177Asp/c.530C>A|751|EZH2|protein_coding|CODING|ENST00000320356|6|T),26533,273,26865,"0,0101619207",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,8,Damaging,"28,76","15,25"
"low bq, low freq, many artifacts, many samples",UPN2_079,7,148525927,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala177Asp/c.530C>A|751|EZH2|protein_coding|CODING|ENST00000320356|6|T),16627,208,16855,"0,0123405518",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,8,Damaging,"28,83","15,98"
"low bq, low freq, many artifacts, many samples",UPN2_080,7,148525927,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala177Asp/c.530C>A|751|EZH2|protein_coding|CODING|ENST00000320356|6|T),22535,265,22860,"0,011592301",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,8,Damaging,"28,78","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_081,7,148525927,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala177Asp/c.530C>A|751|EZH2|protein_coding|CODING|ENST00000320356|6|T),19435,234,19735,"0,0118571067",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,8,Damaging,"28,61","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_082,7,148525927,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala177Asp/c.530C>A|751|EZH2|protein_coding|CODING|ENST00000320356|6|T),40786,454,41354,"0,0109783818",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,8,Damaging,"28,75","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_083,7,148525927,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala177Asp/c.530C>A|751|EZH2|protein_coding|CODING|ENST00000320356|6|T),31638,324,32039,"0,0101126752",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,8,Damaging,"28,79","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_084,7,148525927,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala177Asp/c.530C>A|751|EZH2|protein_coding|CODING|ENST00000320356|6|T),38440,420,38954,"0,0107819479",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,8,Damaging,"28,77","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_085,7,148525927,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala177Asp/c.530C>A|751|EZH2|protein_coding|CODING|ENST00000320356|6|T),47964,529,48621,"0,0108800724",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,8,Damaging,"28,71","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_086,7,148525927,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala177Asp/c.530C>A|751|EZH2|protein_coding|CODING|ENST00000320356|6|T),47745,525,48432,"0,0108399405",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,8,Damaging,"28,8","15,62"
"low bq, low freq, many artifacts, many samples",UPN2_087,7,148525927,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala177Asp/c.530C>A|751|EZH2|protein_coding|CODING|ENST00000320356|6|T),38954,440,39514,"0,0111352938",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,8,Damaging,"28,75","14,98"
"low bq, low freq, many artifacts",UPN2_088,7,148525927,G,T,missense_variant(MODERATE|MISSENSE|gCc/gAc|p.Ala177Asp/c.530C>A|751|EZH2|protein_coding|CODING|ENST00000320356|6|T),30917,316,31331,"0,0100858575",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,8,Damaging,"28,69","15,16"
"low freq, many artifacts",UPN2_006,7,148525933,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val175Glu/c.524T>A|751|EZH2|protein_coding|CODING|ENST00000320356|6|T),10742,117,10902,"0,0107319758",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,91",Deleterious,0,Damaging,"33,88","30,76"
"low freq, low bq",UPN2_056,7,148525944,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe171Leu/c.513T>A|751|EZH2|protein_coding|CODING|ENST00000320356|6|T),3357,41,3425,"0,0119708029",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,99",Deleterious,"0,173",Tolerated,"31,45","25,78"
"many samples, low bq, no database",UPN2_001,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),7715,1173,8898,"0,1318273769",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,86","14,89"
"low bq, many samples",UPN2_014,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),11319,1628,12975,"0,1254720617",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,77","14,5"
"low bq, many samples",UPN2_015,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),15766,2057,17838,"0,1153156183",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,8","14,52"
"low bq, many samples",UPN2_016,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),7501,1102,8614,"0,1279312747",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,76","14,36"
"low bq, many samples",UPN2_017,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),5325,700,6035,"0,115990058",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,86","14,66"
"low bq, many samples",UPN2_018,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),7605,1019,8635,"0,1180081065",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,87","14,47"
"low bq, many samples",UPN2_019,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),8899,1113,10030,"0,1109670987",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,86","14,5"
"low bq, many samples",UPN2_020,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),7410,1047,8473,"0,1235689838",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,76","14,38"
"low bq, many samples",UPN2_021,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),8352,1124,9488,"0,11846543",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,77","14,43"
"low bq, many samples",UPN2_002,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),9548,1341,10902,"0,1230049532",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,93","14,89"
"low bq, many samples",UPN2_003,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),1832,256,2094,"0,1222540592",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,5","14,76"
"low bq, many samples",UPN2_022,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),12118,1597,13732,"0,1162976988",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,71","14,34"
"low bq, many samples",UPN2_023,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),13131,1829,14984,"0,1220635344",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,76","14,55"
"low bq, many samples",UPN2_024,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),6260,810,7083,"0,1143583227",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,78","14,51"
"low bq, many samples",UPN2_025,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),13174,1785,14987,"0,1191032228",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,56","14,46"
"low bq, many samples",UPN2_026,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),15125,1865,17021,"0,1095705305",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,85","14,43"
"low bq, many samples",UPN2_004,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),1352,184,1538,"0,1196358908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,86","14,61"
"low bq, many samples",UPN2_027,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),15669,1996,17689,"0,1128384872",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,79","14,49"
"low bq, many samples",UPN2_089,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),10809,1279,12104,"0,1056675479",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,69","15,53"
"many samples, low bq, no database",UPN2_042,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),14439,2710,17180,"0,15774156",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,25","15,19"
"low bq, many samples",UPN2_028,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),11751,1545,13321,"0,1159822836",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,86","14,53"
"many samples, low bq, no database",UPN2_043,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),11718,2191,13941,"0,1571623269",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,12","15,16"
"many samples, low bq, no database",UPN2_044,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),5157,949,6119,"0,1550907011",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,32","15,17"
"low bq, many samples",UPN2_029,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),14304,1832,16174,"0,1132682082",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,66","14,49"
"low bq, many samples",UPN2_030,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),12597,1736,14352,"0,1209587514",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,87","14,46"
"low bq, many samples",UPN2_031,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),7643,1139,8793,"0,1295348573",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,76","14,45"
"low bq, many samples",UPN2_005,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),2752,394,3151,"0,1250396699",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,30,"14,84"
"low bq, many samples",UPN2_045,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),16005,2925,18961,"0,1542640156",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,18","15,28"
"low bq, many samples",UPN2_032,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),4988,695,5695,"0,1220368745",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,8","14,5"
"many samples, low bq, no database",UPN2_046,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),15547,2802,18384,"0,1524151436",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,33","15,26"
"low bq, many samples",UPN2_033,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),9987,1416,11443,"0,1237437735",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,64","14,52"
"low bq, many samples",UPN2_034,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),3953,459,4420,"0,1038461538",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,71","14,36"
"many samples, low bq, no database",UPN2_047,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),17070,3061,20158,"0,151850382",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,33","15,15"
"low bq, many samples",UPN2_048,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),1587,271,1860,"0,1456989247",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,2","15,32"
"low bq, many samples",UPN2_035,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),17458,2397,19895,"0,1204825333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,75","14,44"
"low bq, many samples",UPN2_036,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),14273,1980,16304,"0,1214425908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,68","14,53"
"low bq, many samples",UPN2_006,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),9431,1405,10847,"0,129528902",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,03","14,97"
"many samples, low bq, no database",UPN2_049,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),11633,2108,13779,"0,1529864286",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,22","15,17"
"many samples, low bq, no database",UPN2_050,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),16738,3125,19918,"0,1568932624",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,37","15,21"
"low bq, many samples",UPN2_037,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),18197,2326,20544,"0,113220405",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,74","14,5"
"many samples, low bq, no database",UPN2_051,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),12719,2256,14997,"0,150430086",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,32","15,21"
"many samples, low bq, no database",UPN2_052,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),13638,2453,16115,"0,15221843",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,26","15,14"
"low bq, many samples",UPN2_038,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),19600,2649,22287,"0,1188585274",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,81","14,5"
"low bq, many samples",UPN2_039,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),11126,1477,12659,"0,1166758828",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,83","14,43"
"many samples, low bq, no database",UPN2_053,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),17489,2976,20509,"0,1451070262",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,33","15,21"
"many samples, low bq, no database",UPN2_054,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),12872,2297,15200,"0,1511184211",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,28","15,19"
"many samples, low bq, no database",UPN2_007,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),22270,3431,25731,"0,1333411061",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,88","14,84"
"low bq, many samples",UPN2_008,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),29630,4322,34025,"0,1270242469",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,93","14,94"
"many samples, low bq, no database",UPN2_009,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),23758,3609,27418,"0,131628857",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,94","15,03"
"many samples, low bq, no database",UPN2_010,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),16339,2344,18707,"0,1253006896",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,98","14,87"
"many samples, low bq, no database",UPN2_011,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),20880,3128,24047,"0,1300785961",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,84","14,95"
"low bq, many samples",UPN2_055,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),17733,3257,21022,"0,1549329274",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,22","15,15"
"low bq, many samples",UPN2_056,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),2881,525,3407,"0,1540945113",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,19","15,27"
"low bq, many samples",UPN2_090,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),9742,1084,10844,"0,0999631132",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,69","15,35"
"many samples, low bq, no database",UPN2_057,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),18273,3389,21713,"0,1560816101",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,18","15,12"
"many samples, low bq, no database",UPN2_058,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),16858,3077,19965,"0,1541197095",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,14","15,24"
"low bq, many samples",UPN2_059,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),21258,1249,22571,"0,0553364937",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,61","15,57"
"low bq, many samples",UPN2_012,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),9112,1388,10511,"0,1320521359",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,78","15,08"
"low bq, many samples",UPN2_060,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),23068,1337,24465,"0,0546494993",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,74","15,4"
"low bq, many samples",UPN2_040,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),7593,1052,8666,"0,1213939534",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,67","14,4"
"low bq, many samples",UPN2_013,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),5189,779,5982,"0,1302240053",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,85","14,8"
"many samples, low bq, no database",UPN2_091,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),9542,1171,10722,"0,1092146988",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,62","15,54"
"low bq, many samples",UPN2_092,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),7525,849,8376,"0,1013610315",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,71","15,68"
"low bq, many samples",UPN2_093,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),7703,1005,8724,"0,1151994498",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,59","15,55"
"low bq, many samples",UPN2_061,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),25313,1412,26769,"0,0527475812",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,65","15,52"
"low bq, many samples",UPN2_062,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),21883,1148,23098,"0,0497012728",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,74","15,58"
"low bq, many samples",UPN2_063,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),22463,1222,23736,"0,0514829794",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,71","15,65"
"low bq, many samples",UPN2_064,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),19231,1137,20409,"0,0557107159",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,65","15,62"
"low bq, many samples",UPN2_065,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),26666,1537,28263,"0,0543820543",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,61","15,58"
"low bq, many samples",UPN2_066,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),52029,2945,55093,"0,0534550669",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,72","15,7"
"low bq, many samples",UPN2_067,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),52627,3242,55999,"0,057893891",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,46","15,59"
"low bq, many samples",UPN2_068,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),31836,1687,33599,"0,0502098277",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,77","15,38"
"low bq, many samples",UPN2_069,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),30679,1772,32524,"0,0544828434",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,7","15,66"
"low bq, many samples",UPN2_070,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),20381,1095,21532,"0,0508545421",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,75","15,69"
"low bq, many samples",UPN2_071,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),16754,1051,17853,"0,0588696578",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,51","15,48"
"low bq, many samples",UPN2_072,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),18894,1089,20021,"0,0543928875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,65","15,47"
"low bq, many samples",UPN2_073,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),16210,924,17170,"0,0538147932",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,54","15,29"
"low bq, many samples",UPN2_074,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),21044,1294,22382,"0,0578143151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,61","15,5"
"low bq, many samples",UPN2_075,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),28773,1793,30638,"0,0585220967",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,5","15,45"
"low bq, many samples",UPN2_076,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),25320,1366,26731,"0,0511017171",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,84","15,69"
"low bq, many samples",UPN2_077,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),30996,1680,32757,"0,0512867479",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,61","15,43"
"low bq, many samples",UPN2_078,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),23656,1225,24940,"0,0491178829",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,73","15,66"
"low bq, many samples",UPN2_079,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),15901,894,16817,"0,0531604924",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,73","15,29"
"low bq, many samples",UPN2_080,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),21458,1223,22733,"0,0537984428",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,6","15,55"
"low bq, many samples",UPN2_081,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),18445,1128,19617,"0,057501147",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,47","15,57"
"low bq, many samples",UPN2_082,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),38822,2258,41191,"0,0548178",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,53","15,63"
"low bq, many samples",UPN2_083,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),30210,1590,31900,"0,0498432602",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,8","15,38"
"low bq, many samples",UPN2_084,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),36704,2018,38816,"0,0519888706",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,67","15,47"
"low bq, many samples",UPN2_085,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),45779,2568,48473,"0,0529779465",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,62","15,69"
"low bq, many samples",UPN2_086,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),45687,2465,48280,"0,051056338",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,74","15,45"
"low bq, many samples",UPN2_087,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),37164,2149,39407,"0,0545334585",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,59","15,47"
"low bq, many samples",UPN2_088,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),29385,1787,31239,"0,0572041359",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,43","15,58"
"many samples, low bq, no database",UPN2_094,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),9538,1171,10715,"0,1092860476",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,63","15,67"
"low bq, many samples",UPN2_095,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),10617,1278,11912,"0,1072867696",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,68","15,58"
"low bq, many samples",UPN2_096,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),10011,1304,11340,"0,1149911817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,67","15,42"
"low bq, many samples",UPN2_097,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),10759,1237,12022,"0,1028946931",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,58","15,48"
"low bq, many samples",UPN2_098,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),11057,1392,12463,"0,1116906042",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,72","15,39"
"low bq, many samples",UPN2_099,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),5722,707,6435,"0,1098679099",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,72","15,27"
"low bq, many samples",UPN2_100,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),7813,878,8715,"0,1007458405",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,78","15,29"
"low bq, many samples",UPN2_101,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),9936,1170,11117,"0,1052442206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,72","15,67"
"low bq, many samples",UPN2_102,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),10325,1228,11575,"0,1060907127",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,56","15,63"
"many samples, low bq, no database",UPN2_103,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),8991,1100,10110,"0,1088031652",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,65","15,48"
"low bq, many samples",UPN2_104,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),11683,1354,13060,"0,1036753446",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,57","15,53"
"many samples, low bq, no database",UPN2_105,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),9159,1102,10280,"0,1071984436",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,69","15,5"
"many samples, low bq, no database",UPN2_106,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),10715,1317,12043,"0,1093581334",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,59","15,61"
"low bq, many samples",UPN2_107,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),18958,2317,21325,"0,1086518171",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,65","15,49"
"low bq, many samples",UPN2_108,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),13578,1781,15388,"0,1157395373",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,67","15,55"
"low bq, many samples",UPN2_109,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),14542,1712,16267,"0,105243745",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,71","15,58"
"low bq, many samples",UPN2_110,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),13151,1549,14707,"0,1053239954",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,76","15,46"
low bq,UPN2_111,7,148525952,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu169*/c.505G>T|751|EZH2|protein_coding|CODING|ENST00000320356|6|A),13131,1560,14710,"0,1060503059",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,72","15,41"
"low freq, many artifacts",UPN2_056,7,148525958,TTA,T,frameshift_variant(HIGH||ata/|p.Ile166fs/c.497_498delTA|751|EZH2|protein_coding|CODING|ENST00000320356|6|T),1665,24,1700,"0,0141176471",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"24,66",NA
"low bq, low freq, many artifacts",UPN2_043,7,148525963,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe165Tyr/c.494T>A|751|EZH2|protein_coding|CODING|ENST00000320356|6|T),6858,73,6965,"0,0104809763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,22,Damaging,"33,92","17,27"
"low bq, low freq, many artifacts, many samples",UPN2_043,7,148525968,A,T,stop_gained(HIGH|NONSENSE|tgT/tgA|p.Cys163*/c.489T>A|751|EZH2|protein_coding|CODING|ENST00000320356|6|T),6860,77,6968,"0,0110505166",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,04","20,09"
"low bq, low freq, many artifacts, many samples",UPN2_045,7,148525968,A,T,stop_gained(HIGH|NONSENSE|tgT/tgA|p.Cys163*/c.489T>A|751|EZH2|protein_coding|CODING|ENST00000320356|6|T),9311,113,9456,"0,0119500846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,93","21,2"
"low freq, many artifacts, many samples",UPN2_006,7,148525968,A,T,stop_gained(HIGH|NONSENSE|tgT/tgA|p.Cys163*/c.489T>A|751|EZH2|protein_coding|CODING|ENST00000320356|6|T),5341,65,5416,"0,0120014771",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,52","27,14"
"low bq, low freq, many artifacts, many samples",UPN2_054,7,148525968,A,T,stop_gained(HIGH|NONSENSE|tgT/tgA|p.Cys163*/c.489T>A|751|EZH2|protein_coding|CODING|ENST00000320356|6|T),7493,85,7600,"0,0111842105",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,09","21,22"
"low bq, low freq, many artifacts",UPN2_055,7,148525968,A,T,stop_gained(HIGH|NONSENSE|tgT/tgA|p.Cys163*/c.489T>A|751|EZH2|protein_coding|CODING|ENST00000320356|6|T),10350,123,10506,"0,0117075957",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,01","21,54"
"low freq, many artifacts",UPN2_004,7,148526829,C,T,missense_variant(MODERATE|MISSENSE|Ggg/Agg|p.Gly159Arg/c.475G>A|751|EZH2|protein_coding|CODING|ENST00000320356|5|T),1840,20,1862,"0,0107411386",0,0,0,0,1,0,0,1,2,NO,NO,COSM96480,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,"-7,25",Deleterious,"0,001",Damaging,"35,49","35,6"
"inspected, homopolymer 6T",UPN2_058,7,148526848,AT,A,frameshift_variant(HIGH||aat/|p.Asn152fs/c.455delA|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),14232,632,14969,"0,0422205892",0,0,0,0,0,1,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,35,NA
"low freq, many artifacts",UPN2_012,7,148526848,AT,A,frameshift_variant(HIGH||aat/|p.Asn152fs/c.455delA|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),8672,90,8843,"0,0101775416",0,0,0,0,0,0,0,1,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,9",NA
"low freq, many artifacts",UPN2_048,7,148526871,A,G,missense_variant(MODERATE|MISSENSE|Ttc/Ctc|p.Phe145Leu/c.433T>C|751|EZH2|protein_coding|CODING|ENST00000320356|5|G),2560,30,2598,"0,0115473441",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,99",Deleterious,"0,002",Damaging,"34,82","34,7"
"low freq, many artifacts",UPN2_048,7,148526873,G,A,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr144Ile/c.431C>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),2565,29,2598,"0,0111624326",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,35",Deleterious,"0,012",Damaging,"34,52","34,21"
"low bq, low freq, many artifacts",UPN2_048,7,148526877,C,A,missense_variant(MODERATE|MISSENSE|Ggt/Tgt|p.Gly143Cys/c.427G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),2560,27,2597,"0,0103966115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,22",Deleterious,9,Damaging,"31,3",14
"low bq, low freq, many artifacts",UPN2_048,7,148526898,C,A,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp136Tyr/c.406G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),2542,27,2601,"0,0103806228",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,51",Deleterious,0,Damaging,"31,36","15,48"
"low freq, many artifacts",UPN2_048,7,148526898,C,T,missense_variant(MODERATE|MISSENSE|Gat/Aat|p.Asp136Asn/c.406G>A|751|EZH2|protein_coding|CODING|ENST00000320356|5|T),2542,31,2601,"0,0119184929",0,0,0,0,0,0,0,1,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,72",Deleterious,1,Damaging,"31,36","35,16"
"low bq, low freq, many artifacts, many samples",UPN2_014,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),17437,240,17762,"0,0135119919",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"29,51","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_015,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),26066,324,26496,"0,0122282609",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"29,72","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_016,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),13095,178,13314,"0,0133693856",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"29,54","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_017,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),8731,125,8883,"0,0140718226",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"29,9","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_018,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),13413,170,13634,"0,0124688279",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"29,78","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_019,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),15389,195,15658,"0,0124536978",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"29,88","15,82"
"low bq, low freq, many artifacts, many samples",UPN2_020,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),12022,166,12226,"0,0135776215",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"29,55","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_021,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),13723,172,13937,"0,0123412499",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"29,59","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_002,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),16391,189,16621,"0,011371157",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"31,79","15,62"
"low bq, low freq, many artifacts, many samples",UPN2_022,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),20421,297,20779,"0,0142932769",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"29,78","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_023,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),21286,255,21600,"0,0118055556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"29,72","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_024,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),10455,134,10629,"0,0126070185",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"29,68","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_025,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),21582,278,21932,"0,0126755426",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"29,72","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_026,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),23785,304,24173,"0,0125760146",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"29,77","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_027,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),25507,316,25889,"0,0122059562",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"29,79","16,01"
"low bq, low freq, many artifacts, many samples",UPN2_089,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),16555,327,16933,"0,0193114038",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,41","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_042,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),25868,527,26520,"0,0198717949",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,8","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_043,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),21492,474,22086,"0,0214615594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,84","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_044,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),11232,242,11504,"0,0210361613",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,99","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_029,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),24764,323,25189,"0,0128230577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"29,74","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_030,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),20278,244,20576,"0,0118584759",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"29,75","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_031,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),12622,164,12833,"0,0127795527",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"29,61","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_005,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),4828,49,4891,"0,0100184011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"32,04","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_045,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),22874,474,23467,"0,0201985767",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,8","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_032,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),8955,129,9117,"0,0141493912",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"29,65","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_046,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),28716,601,29492,"0,0203784077",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,92","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_033,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),17321,237,17601,"0,013465144",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"29,55","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_034,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),6404,85,6513,"0,0130508214",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"29,78","14,86"
"low bq, many samples",UPN2_047,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),34522,782,35447,"0,0220611053",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,78","15,11"
"low bq, many samples",UPN2_048,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),4955,119,5098,"0,0233424872",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,8","15,17"
"low bq, low freq, many artifacts, many samples",UPN2_035,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),33463,442,34023,"0,0129912118",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"29,58","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_036,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),26665,377,27140,"0,0138909359",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"29,63","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_006,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),19554,220,19860,"0,0110775428",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"31,81","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_049,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),21595,438,22113,"0,0198073531",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,92","15,08"
"low bq, many samples",UPN2_050,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),24016,543,24655,"0,0220239302",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,91","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_037,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),30243,373,30703,"0,01214865",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"29,76","15,1"
"low bq, many samples",UPN2_051,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),22743,527,23378,"0,0225425614",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,93","15,34"
"low bq, low freq, many artifacts, many samples",UPN2_052,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),20332,424,20850,"0,0203357314",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,95","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_038,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),35834,434,36384,"0,0119283201",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"29,71","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_039,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),19702,256,20024,"0,0127846584",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"29,76","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_053,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),30774,650,31565,"0,0205924283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"29,01","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_054,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),22780,504,23391,"0,0215467487",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,96","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_007,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),36422,479,36997,"0,0129469957",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"31,66","16,03"
"low bq, low freq, many artifacts, many samples",UPN2_008,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),45672,528,46334,"0,0113955195",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"31,82","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_009,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),38068,412,38581,"0,0106788315",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"31,75","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_010,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),28773,366,29260,"0,0125085441",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"31,68","15,37"
"low bq, low freq, many artifacts, many samples",UPN2_011,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),37621,431,38218,"0,0112774086",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"31,67","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_055,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),30629,560,31324,"0,0178776657",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,93",15
"low bq, low freq, many artifacts, many samples",UPN2_056,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),6860,152,7050,"0,0215602837",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,76","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_090,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),13791,276,14105,"0,0195675292",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,44","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_057,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),33067,724,33985,"0,0213035163",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,89","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_058,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),28547,579,29270,"0,0197813461",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,83","14,8"
"low bq, many samples",UPN2_059,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),23544,575,24226,"0,0237348303",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,3","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_012,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),17084,219,17349,"0,0126232059",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"31,57","15,53"
"low bq, low freq, many artifacts, many samples",UPN2_060,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),21994,475,22548,"0,0210661699",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,3","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_040,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),14609,177,14839,"0,0119280275",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"29,72","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_013,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),9625,102,9758,"0,0104529617",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"31,65","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_091,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),13575,234,13833,"0,0169160703",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,42","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_092,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),11958,209,12205,"0,0171241295",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,34","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_093,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),12779,224,13030,"0,0171910975",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,46","14,53"
"low bq, many samples",UPN2_061,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),22835,533,23477,"0,0227030711",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,44","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_062,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),21744,454,22307,"0,0203523558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,45","15,19"
"low bq, many samples",UPN2_063,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),22423,546,23130,"0,0236057069",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,31","15,21"
"low bq, many samples",UPN2_064,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),23054,565,23762,"0,0237774598",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,29","14,92"
"low bq, many samples",UPN2_065,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),27844,689,28675,"0,0240278989",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,28","14,8"
"low bq, many samples",UPN2_066,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),45813,1117,47128,"0,0237014089",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,3","15,08"
"low bq, many samples",UPN2_067,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),49027,1194,50469,"0,0236580871",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,23","15,22"
"low bq, many samples",UPN2_068,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),29587,721,30484,"0,0236517517",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,41","14,93"
"low bq, many samples",UPN2_069,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),28058,667,28845,"0,0231235916",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,29","15,06"
"low bq, many samples",UPN2_070,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),19277,467,19827,"0,0235537398",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,41","15,12"
"low bq, many samples",UPN2_071,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),14613,374,15062,"0,0248306998",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,41","15,09"
"low bq, many samples",UPN2_072,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),19561,494,20139,"0,0245295198",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,29","15,04"
"low bq, many samples",UPN2_073,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),15824,384,16316,"0,0235351802",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,15","15,23"
"low bq, many samples",UPN2_074,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),18044,437,18567,"0,0235363818",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,26","15,05"
"low bq, many samples",UPN2_075,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),12518,299,12874,"0,0232251049",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,23","15,19"
"low bq, many samples",UPN2_076,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),21466,494,22046,"0,022407693",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,36","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_077,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),28978,625,29750,"0,0210084034",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,32","14,77"
"low bq, many samples",UPN2_078,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),21037,504,21635,"0,0232955859",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,39","15,09"
"low bq, many samples",UPN2_079,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),14537,382,14986,"0,0254904578",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,26","15,41"
"low bq, many samples",UPN2_080,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),21105,527,21724,"0,0242588842",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,28","14,86"
"low bq, many samples",UPN2_081,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),21947,580,22624,"0,0256364922",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,29","14,87"
"low bq, many samples",UPN2_082,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),37092,906,38197,"0,0237191402",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,33","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_083,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),26818,584,27483,"0,0212494997",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,46","15,02"
"low bq, many samples",UPN2_084,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),17947,420,18456,"0,022756827",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,31","14,9"
"low bq, many samples",UPN2_085,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),42596,1010,43820,"0,0230488361",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,38","15,16"
"low bq, many samples",UPN2_086,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),38720,923,39837,"0,0231694154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,36","15,32"
"low bq, many samples",UPN2_087,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),34384,809,35374,"0,0228699044",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,31","15,02"
"low bq, many samples",UPN2_088,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),25118,595,25814,"0,023049508",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,27","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_094,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),10629,205,10853,"0,0188887865",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,49","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_095,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),16203,312,16573,"0,018825801",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,5","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_096,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),13683,248,13942,"0,0177879788",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,37","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_097,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),13568,269,13861,"0,0194069692",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,3","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_098,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),15850,337,16242,"0,0207486763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,46","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_099,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),8368,147,8545,"0,0172030427",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,51","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_100,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),8598,157,8775,"0,0178917379",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,46","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_101,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),14556,258,14848,"0,0173760776",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,44","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_102,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),15696,280,16014,"0,0174847009",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,41","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_103,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),11282,185,11492,"0,0160981552",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,48","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_104,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),14407,244,14683,"0,0166178574",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,37","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_105,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),10223,189,10442,"0,0180999808",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,28","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_106,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),10245,194,10470,"0,0185291309",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,29","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_107,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),23216,456,23782,"0,0191741653",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,48","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_108,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),13677,256,13959,"0,0183394226",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,43","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_109,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),15032,276,15346,"0,0179851427",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,37","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_110,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),12758,246,13036,"0,0188708193",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,39","14,76"
"low bq, low freq, many artifacts",UPN2_111,7,148526900,C,A,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly135Val/c.404G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),17771,312,18131,"0,0172080966",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,68",Deleterious,1,Damaging,"28,42","14,72"
"low bq, low freq, many artifacts",UPN2_060,7,148526901,C,A,stop_gained(HIGH|NONSENSE|Gga/Tga|p.Gly135*/c.403G>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),22439,234,22716,"0,0103011094",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,25","16,66"
"low bq, low freq, many artifacts, many samples",UPN2_003,7,148526909,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro132His/c.395C>A|751|EZH2|protein_coding|CODING|ENST00000320356|5|T),3199,38,3239,"0,0117320161",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,67",Deleterious,1,Damaging,"30,58","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_042,7,148526909,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro132His/c.395C>A|751|EZH2|protein_coding|CODING|ENST00000320356|5|T),26435,272,26810,"0,0101454681",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,67",Deleterious,1,Damaging,"28,93","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_044,7,148526909,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro132His/c.395C>A|751|EZH2|protein_coding|CODING|ENST00000320356|5|T),11433,190,11668,"0,0162838533",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,67",Deleterious,1,Damaging,"28,92","21,82"
"low bq, low freq, many artifacts, many samples",UPN2_045,7,148526909,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro132His/c.395C>A|751|EZH2|protein_coding|CODING|ENST00000320356|5|T),23366,267,23709,"0,0112615462",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,67",Deleterious,1,Damaging,"28,86","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_047,7,148526909,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro132His/c.395C>A|751|EZH2|protein_coding|CODING|ENST00000320356|5|T),35281,383,35820,"0,0106923506",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,67",Deleterious,1,Damaging,"28,91","15,96"
"low bq, low freq, many artifacts, many samples",UPN2_050,7,148526909,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro132His/c.395C>A|751|EZH2|protein_coding|CODING|ENST00000320356|5|T),24580,275,24939,"0,0110269056",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,67",Deleterious,1,Damaging,"28,82","15,5"
"low bq, low freq, many artifacts, many samples",UPN2_051,7,148526909,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro132His/c.395C>A|751|EZH2|protein_coding|CODING|ENST00000320356|5|T),23287,258,23625,"0,0109206349",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,67",Deleterious,1,Damaging,"28,92","15,45"
"low bq, low freq, many artifacts, many samples",UPN2_052,7,148526909,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro132His/c.395C>A|751|EZH2|protein_coding|CODING|ENST00000320356|5|T),20782,214,21066,"0,0101585493",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,67",Deleterious,1,Damaging,"28,83","15,65"
"low bq, low freq, many artifacts, many samples",UPN2_053,7,148526909,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro132His/c.395C>A|751|EZH2|protein_coding|CODING|ENST00000320356|5|T),31528,327,31957,"0,0102324999",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,67",Deleterious,1,Damaging,"28,86","15,31"
"low bq, low freq, many artifacts, many samples",UPN2_056,7,148526909,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro132His/c.395C>A|751|EZH2|protein_coding|CODING|ENST00000320356|5|T),7028,73,7116,"0,0102585722",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,67",Deleterious,1,Damaging,"28,89","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_059,7,148526909,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro132His/c.395C>A|751|EZH2|protein_coding|CODING|ENST00000320356|5|T),24192,248,24537,"0,0101071851",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,67",Deleterious,1,Damaging,"28,77","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_065,7,148526909,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro132His/c.395C>A|751|EZH2|protein_coding|CODING|ENST00000320356|5|T),28651,307,29081,"0,0105567209",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,67",Deleterious,1,Damaging,"28,67","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_067,7,148526909,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro132His/c.395C>A|751|EZH2|protein_coding|CODING|ENST00000320356|5|T),50457,543,51200,"0,0106054688",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,67",Deleterious,1,Damaging,"28,64","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_070,7,148526909,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro132His/c.395C>A|751|EZH2|protein_coding|CODING|ENST00000320356|5|T),19816,202,20090,"0,0100547536",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,67",Deleterious,1,Damaging,"28,74","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_072,7,148526909,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro132His/c.395C>A|751|EZH2|protein_coding|CODING|ENST00000320356|5|T),20133,230,20439,"0,0112529967",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,67",Deleterious,1,Damaging,"28,73",15
"low bq, low freq, many artifacts, many samples",UPN2_073,7,148526909,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro132His/c.395C>A|751|EZH2|protein_coding|CODING|ENST00000320356|5|T),16269,190,16524,"0,0114984265",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,67",Deleterious,1,Damaging,"28,67","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_074,7,148526909,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro132His/c.395C>A|751|EZH2|protein_coding|CODING|ENST00000320356|5|T),18499,199,18788,"0,0105918671",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,67",Deleterious,1,Damaging,"28,73","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_075,7,148526909,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro132His/c.395C>A|751|EZH2|protein_coding|CODING|ENST00000320356|5|T),12868,141,13062,"0,0107946716",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,67",Deleterious,1,Damaging,"28,57","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_076,7,148526909,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro132His/c.395C>A|751|EZH2|protein_coding|CODING|ENST00000320356|5|T),22070,227,22385,"0,0101407192",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,67",Deleterious,1,Damaging,"28,78","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_078,7,148526909,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro132His/c.395C>A|751|EZH2|protein_coding|CODING|ENST00000320356|5|T),21608,226,21936,"0,0103026988",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,67",Deleterious,1,Damaging,"28,78","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_080,7,148526909,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro132His/c.395C>A|751|EZH2|protein_coding|CODING|ENST00000320356|5|T),21701,236,22018,"0,010718503",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,67",Deleterious,1,Damaging,"28,64","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_081,7,148526909,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro132His/c.395C>A|751|EZH2|protein_coding|CODING|ENST00000320356|5|T),22564,244,22893,"0,0106582798",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,67",Deleterious,1,Damaging,"28,71","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_082,7,148526909,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro132His/c.395C>A|751|EZH2|protein_coding|CODING|ENST00000320356|5|T),38190,407,38736,"0,0105070219",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,67",Deleterious,1,Damaging,"28,71","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_085,7,148526909,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro132His/c.395C>A|751|EZH2|protein_coding|CODING|ENST00000320356|5|T),43778,449,44395,"0,0101137515",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,67",Deleterious,1,Damaging,"28,67","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_086,7,148526909,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro132His/c.395C>A|751|EZH2|protein_coding|CODING|ENST00000320356|5|T),39791,428,40396,"0,0105951084",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,67",Deleterious,1,Damaging,"28,67","14,82"
"low bq, low freq, many artifacts",UPN2_088,7,148526909,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro132His/c.395C>A|751|EZH2|protein_coding|CODING|ENST00000320356|5|T),25793,271,26178,"0,0103522041",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,67",Deleterious,1,Damaging,"28,66","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_050,7,148526935,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu123Asp/c.369A>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),24585,255,24974,"0,010210619",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,168,Tolerated,"29,35","17,5"
"low bq, low freq, many artifacts, many samples",UPN2_052,7,148526935,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu123Asp/c.369A>T|751|EZH2|protein_coding|CODING|ENST00000320356|5|A),20761,231,21085,"0,0109556557",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,168,Tolerated,"29,34","19,34"
"low bq, low freq, many artifacts, many samples",UPN2_001,7,148529726,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2372,32,2406,"0,0133000831",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"30,43",14
"low bq, low freq, many artifacts, many samples",UPN2_016,7,148529726,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2625,28,2655,"0,0105461394",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"28,8","16,04"
"low bq, low freq, many artifacts, many samples",UPN2_018,7,148529726,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2402,32,2441,"0,0131093814",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"28,72","15,66"
"low bq, low freq, many artifacts, many samples",UPN2_089,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3863,47,3919,"0,0119928553",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"30,06","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_042,7,148529726,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),1117,20,1138,"0,0175746924",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"29,55","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_043,7,148529726,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2311,37,2351,"0,0157379838",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"29,61","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_031,7,148529726,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2181,23,2205,"0,010430839",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"28,68","16,13"
"low bq, low freq, many artifacts, many samples",UPN2_045,7,148529726,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2927,46,2980,"0,0154362416",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"29,58","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_046,7,148529726,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3318,63,3385,"0,0186115214",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"29,92","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_033,7,148529726,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3050,32,3087,"0,0103660512",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"28,75",14
"low bq, low freq, many artifacts, many samples",UPN2_006,7,148529726,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),1477,25,1502,"0,016644474",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"30,08","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_050,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2973,63,3044,"0,020696452",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"29,65","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_051,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3277,48,3329,"0,0144187444",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"29,99","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_052,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3281,60,3344,"0,0179425837",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"29,76",14
"low bq, low freq, many artifacts, many samples",UPN2_053,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),4847,79,4932,"0,0160178427",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"29,71","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_054,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3131,46,3182,"0,0144563168",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"29,88","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_007,7,148529726,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),7269,120,7393,"0,0162315704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"29,8","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_008,7,148529726,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),9819,147,9976,"0,0147353649",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"30,07","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_009,7,148529726,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),7675,110,7791,"0,0141188551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"30,03","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_010,7,148529726,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),5630,85,5736,"0,014818689",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"29,97","15,51"
"low bq, low freq, many artifacts, many samples",UPN2_011,7,148529726,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),7219,96,7326,"0,0131040131",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"30,05","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_055,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3444,44,3494,"0,0125930166",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"29,68",15
"low bq, low freq, many artifacts, many samples",UPN2_057,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),4187,69,4267,"0,0161706117",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"29,94","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_058,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),5587,91,5690,"0,0159929701",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"29,66","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_012,7,148529726,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2495,50,2546,"0,0196386489",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"29,72",14
"low bq, low freq, many artifacts, many samples",UPN2_060,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3918,86,4010,"0,021446384",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"29,01","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_013,7,148529726,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),1911,23,1936,"0,0118801653",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"30,12",14
"low bq, low freq, many artifacts, many samples",UPN2_092,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2420,31,2453,"0,0126375866",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"30,27","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_093,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3166,38,3204,"0,0118601748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"29,92","15,68"
"low bq, low freq, many artifacts, many samples",UPN2_061,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),5329,100,5440,"0,0183823529",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"29,12","15,38"
"low bq, many samples",UPN2_062,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3554,80,3636,"0,0220022002",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"29,26","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_063,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),4286,82,4374,"0,0187471422",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"28,93","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_065,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2956,57,3013,"0,0189180219",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"28,7","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_066,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),9682,178,9874,"0,018027142",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"29,1","14,87"
"low bq, many samples",UPN2_067,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),11733,265,12015,"0,0220557636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"28,97","15,65"
"low bq, low freq, many artifacts, many samples",UPN2_068,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),7844,151,8007,"0,0188584988",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"29,18","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_069,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),6391,143,6536,"0,021878825",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"29,12","15,4"
"low bq, low freq, many artifacts, many samples",UPN2_070,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),4273,86,4366,"0,0196976638",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"29,34","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_071,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3182,65,3260,"0,0199386503",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"29,07","15,69"
"low bq, low freq, many artifacts, many samples",UPN2_072,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2193,43,2240,"0,0191964286",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"29,22","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_073,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),1649,29,1679,"0,0172721858",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"29,01","15,97"
"low bq, low freq, many artifacts, many samples",UPN2_074,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),4248,78,4331,"0,0180096975",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"29,09","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_075,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),5362,107,5473,"0,0195505207",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"28,94","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_076,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),5007,79,5095,"0,0155053974",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"29,1","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_077,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),7473,154,7641,"0,02015443",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"29,18","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_078,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),5068,97,5175,"0,0187439614",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"29,14","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_079,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3389,58,3448,"0,0168213457",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"29,03","14,84"
"low bq, many samples",UPN2_080,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2871,65,2941,"0,0221013261",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"29,07","15,69"
"low bq, low freq, many artifacts, many samples",UPN2_081,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),1140,22,1164,"0,0189003436",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"28,92",14
"low bq, many samples",UPN2_082,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),7612,176,7793,"0,0225843706",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"29,02","15,41"
"low bq, low freq, many artifacts, many samples",UPN2_083,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),6630,128,6766,"0,01891812",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"29,2","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_084,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),8552,166,8721,"0,0190345144",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"29,09","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_085,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),6915,131,7051,"0,018578925",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"28,95","15,4"
"low bq, low freq, many artifacts, many samples",UPN2_086,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),6338,110,6457,"0,0170357751",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"29,02","15,27"
"low bq, many samples",UPN2_087,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),7801,180,7992,"0,0225225225",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"28,99","15,26"
"low bq, many samples",UPN2_088,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),5580,126,5711,"0,022062686",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"28,98","15,25"
"low bq, low freq, many artifacts, many samples",UPN2_094,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2873,36,2909,"0,0123753867",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"29,88",14
"low bq, low freq, many artifacts, many samples",UPN2_095,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3894,42,3943,"0,010651788",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"30,03",14
"low bq, low freq, many artifacts, many samples",UPN2_096,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3431,35,3469,"0,0100893629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"30,02","16,34"
"low bq, low freq, many artifacts, many samples",UPN2_098,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2914,34,2951,"0,0115215181",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"29,84",14
"low bq, low freq, many artifacts, many samples",UPN2_106,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),1689,21,1711,"0,0122735243",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"30,06","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_108,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3699,52,3757,"0,0138408304",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"29,91","15,21"
"low bq, low freq, many artifacts",UPN2_111,7,148529726,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met121Ile/c.363G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),4816,51,4872,"0,0104679803",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,13,Damaging,"30,11","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_050,7,148529735,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln118His/c.354G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3008,31,3042,"0,010190664",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,51,Tolerated,"32,4","17,97"
"low bq, low freq, many artifacts, many samples",UPN2_051,7,148529735,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln118His/c.354G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3284,34,3328,"0,0102163462",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,51,Tolerated,"32,62","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_055,7,148529735,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln118His/c.354G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3449,35,3493,"0,0100200401",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,51,Tolerated,"32,55","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_060,7,148529735,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln118His/c.354G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3948,57,4007,"0,0142251061",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,51,Tolerated,"31,99","16,77"
"low bq, low freq, many artifacts, many samples",UPN2_062,7,148529735,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln118His/c.354G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3588,41,3634,"0,0112823335",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,51,Tolerated,"32,36","16,73"
"low bq, low freq, many artifacts, many samples",UPN2_063,7,148529735,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln118His/c.354G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),4314,56,4373,"0,0128058541",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,51,Tolerated,"31,95","15,77"
"low bq, low freq, many artifacts, many samples",UPN2_065,7,148529735,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln118His/c.354G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2971,31,3009,"0,0103024261",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,51,Tolerated,"31,85","15,71"
"low bq, low freq, many artifacts, many samples",UPN2_066,7,148529735,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln118His/c.354G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),9747,107,9863,"0,0108486262",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,51,Tolerated,"32,09","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_067,7,148529735,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln118His/c.354G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),11822,170,12006,"0,0141595869",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,51,Tolerated,"32,09","15,65"
"low bq, low freq, many artifacts, many samples",UPN2_068,7,148529735,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln118His/c.354G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),7883,102,8001,"0,0127484064",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,51,Tolerated,"32,14","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_069,7,148529735,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln118His/c.354G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),6437,90,6528,"0,0137867647",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,51,Tolerated,"32,11","15,61"
"low bq, low freq, many artifacts, many samples",UPN2_071,7,148529735,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln118His/c.354G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3208,44,3257,"0,0135093644",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,51,Tolerated,"32,11","16,05"
"low bq, low freq, many artifacts, many samples",UPN2_072,7,148529735,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln118His/c.354G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2206,33,2239,"0,0147387226",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,51,Tolerated,"31,97","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_074,7,148529735,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln118His/c.354G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),4265,55,4325,"0,012716763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,51,Tolerated,"32,15","16,09"
"low bq, low freq, many artifacts, many samples",UPN2_075,7,148529735,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln118His/c.354G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),5382,74,5467,"0,01353576",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,51,Tolerated,"31,91","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_076,7,148529735,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln118His/c.354G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),5032,55,5091,"0,0108033785",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,51,Tolerated,"32,07","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_077,7,148529735,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln118His/c.354G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),7526,97,7633,"0,0127079785",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,51,Tolerated,"32,06","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_080,7,148529735,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln118His/c.354G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2893,42,2939,"0,014290575",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,51,Tolerated,"31,83","15,88"
"low bq, low freq, many artifacts, many samples",UPN2_082,7,148529735,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln118His/c.354G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),7683,97,7786,"0,0124582584",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,51,Tolerated,"31,98","15,81"
"low bq, low freq, many artifacts, many samples",UPN2_083,7,148529735,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln118His/c.354G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),6672,83,6764,"0,0122708457",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,51,Tolerated,"31,99","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_084,7,148529735,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln118His/c.354G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),8597,107,8715,"0,0122776822",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,51,Tolerated,"31,99","15,75"
"low bq, low freq, many artifacts, many samples",UPN2_085,7,148529735,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln118His/c.354G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),6956,75,7042,"0,0106503834",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,51,Tolerated,"31,87","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_086,7,148529735,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln118His/c.354G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),6370,74,6449,"0,0114746472",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,51,Tolerated,"32,06","16,55"
"low bq, low freq, many artifacts, many samples",UPN2_087,7,148529735,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln118His/c.354G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),7859,113,7978,"0,0141639509",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,51,Tolerated,"32,02","15,41"
"low bq, low freq, many artifacts",UPN2_106,7,148529735,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln118His/c.354G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),1686,23,1710,"0,0134502924",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,51,Tolerated,"32,66","16,65"
"low bq, low freq, many artifacts, many samples",UPN2_026,7,148529738,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln117His/c.351G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),4680,50,4741,"0,0105462982",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,94,Tolerated,"28,46","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_045,7,148529738,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln117His/c.351G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2928,40,2978,"0,0134318334",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,94,Tolerated,"30,2","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_046,7,148529738,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln117His/c.351G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3325,41,3380,"0,0121301775",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,94,Tolerated,"30,3","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_052,7,148529738,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln117His/c.351G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3292,41,3342,"0,0122681029",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,94,Tolerated,"30,25","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_053,7,148529738,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln117His/c.351G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),4853,61,4928,"0,0123782468",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,94,Tolerated,"30,28","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_054,7,148529738,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln117His/c.351G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3138,39,3181,"0,0122602955",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,94,Tolerated,"30,24","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_007,7,148529738,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln117His/c.351G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),7297,78,7390,"0,0105548038",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,94,Tolerated,"31,05","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_010,7,148529738,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln117His/c.351G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),5664,59,5728,"0,0103002793",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,94,Tolerated,"31,13","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_055,7,148529738,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln117His/c.351G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3446,41,3493,"0,0117377612",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,94,Tolerated,"30,43",14
"low bq, low freq, many artifacts, many samples",UPN2_057,7,148529738,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln117His/c.351G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),4210,44,4263,"0,0103213699",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,94,Tolerated,"30,16","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_058,7,148529738,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln117His/c.351G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),5586,84,5685,"0,0147757256",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,94,Tolerated,"30,14","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_012,7,148529738,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln117His/c.351G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2511,29,2545,"0,0113948919",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,94,Tolerated,"30,9","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_060,7,148529738,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln117His/c.351G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3929,71,4004,"0,0177322677",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,94,Tolerated,"29,43","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_061,7,148529738,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln117His/c.351G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),5334,84,5428,"0,0154753132",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,94,Tolerated,"29,35",15
"low bq, low freq, many artifacts, many samples",UPN2_062,7,148529738,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln117His/c.351G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3569,56,3631,"0,0154227486",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,94,Tolerated,"29,32","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_063,7,148529738,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln117His/c.351G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),4287,78,4371,"0,0178448868",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,94,Tolerated,"29,35","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_065,7,148529738,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln117His/c.351G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2956,50,3007,"0,0166278683",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,94,Tolerated,"29,07","15,94"
"low bq, low freq, many artifacts, many samples",UPN2_066,7,148529738,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln117His/c.351G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),9678,170,9860,"0,0172413793",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,94,Tolerated,"29,4","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_067,7,148529738,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln117His/c.351G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),11755,229,12000,"0,0190833333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,94,Tolerated,"29,27","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_068,7,148529738,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln117His/c.351G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),7877,114,8000,"0,01425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,94,Tolerated,"29,46","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_069,7,148529738,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln117His/c.351G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),6408,103,6522,"0,0157927016",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,94,Tolerated,"29,38","15,81"
"low bq, low freq, many artifacts, many samples",UPN2_071,7,148529738,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln117His/c.351G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3188,57,3256,"0,0175061425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,94,Tolerated,"29,37","15,95"
"low bq, low freq, many artifacts, many samples",UPN2_072,7,148529738,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln117His/c.351G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2201,33,2237,"0,0147518999",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,94,Tolerated,"29,54","16,52"
"low bq, low freq, many artifacts, many samples",UPN2_073,7,148529738,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln117His/c.351G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),1652,26,1678,"0,0154946365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,94,Tolerated,"29,25","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_074,7,148529738,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln117His/c.351G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),4250,69,4323,"0,0159611381",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,94,Tolerated,"29,3","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_075,7,148529738,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln117His/c.351G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),5353,105,5466,"0,0192096597",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,94,Tolerated,"29,22","15,46"
"low bq, low freq, many artifacts, many samples",UPN2_076,7,148529738,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln117His/c.351G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),4987,89,5088,"0,0174921384",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,94,Tolerated,"29,38","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_077,7,148529738,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln117His/c.351G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),7497,124,7632,"0,0162473795",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,94,Tolerated,"29,38","15,57"
"low bq, low freq, many artifacts, many samples",UPN2_078,7,148529738,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln117His/c.351G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),5075,86,5168,"0,0166408669",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,94,Tolerated,"29,29","15,31"
"low bq, low freq, many artifacts, many samples",UPN2_079,7,148529738,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln117His/c.351G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3389,46,3440,"0,013372093",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,94,Tolerated,"29,28","15,63"
"low bq, low freq, many artifacts, many samples",UPN2_080,7,148529738,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln117His/c.351G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2872,60,2938,"0,0204220558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,94,Tolerated,"29,12","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_082,7,148529738,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln117His/c.351G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),7629,148,7783,"0,0190158037",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,94,Tolerated,"29,19","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_083,7,148529738,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln117His/c.351G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),6631,124,6760,"0,0183431953",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,94,Tolerated,"29,54","15,46"
"low bq, low freq, many artifacts, many samples",UPN2_084,7,148529738,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln117His/c.351G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),8564,142,8715,"0,0162937464",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,94,Tolerated,"29,31","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_085,7,148529738,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln117His/c.351G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),6908,123,7039,"0,017474073",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,94,Tolerated,"29,16","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_086,7,148529738,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln117His/c.351G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),6341,104,6449,"0,0161265312",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,94,Tolerated,"29,37","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_087,7,148529738,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln117His/c.351G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),7818,153,7976,"0,0191825476",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,94,Tolerated,"29,29","14,81"
"low bq, low freq, many artifacts",UPN2_088,7,148529738,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln117His/c.351G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),5603,89,5703,"0,0156058215",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,94,Tolerated,"29,2","14,94"
"low bq, low freq, many artifacts",UPN2_074,7,148529745,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro115His/c.344C>A|751|EZH2|protein_coding|CODING|ENST00000320356|4|T),4268,46,4322,"0,0106432207",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,25",Deleterious,0,Damaging,"30,37","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_001,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2442,39,2488,"0,0156752412",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"27,74",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_015,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),4876,51,4931,"0,0103427297",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"24,99","18,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_017,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),1847,20,1869,"0,0107009096",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"25,21","15,1"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_018,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2514,33,2549,"0,0129462534",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"25,22","14,94"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_019,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2784,43,2830,"0,0151943463",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"25,09","14,93"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_021,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2519,26,2553,"0,0101840971",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"25,15","15,54"
"low bq, low freq, many artifacts, many samples",UPN2_002,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3303,44,3351,"0,0131304088",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"27,52","15,09"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_024,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),1984,21,2008,"0,0104581673",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"24,89","14,33"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_027,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),5993,76,6075,"0,0125102881",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"25,16","16,42"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_089,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3999,56,4062,"0,0137863122",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"26,14","16,25"
"low bq, bad alignment, many samples",UPN2_042,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),1156,27,1184,"0,0228040541",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"26,33","16,44"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_028,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),4072,43,4129,"0,0104141439",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"25,17","16,37"
"low bq, bad alignment, many samples",UPN2_043,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2385,57,2447,"0,0232938292",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"26,64","15,35"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_044,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),1353,23,1376,"0,0167151163",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"26,56","14,96"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_029,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),4741,51,4803,"0,0106183635",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"25,13","15,04"
"low bq, many samples",UPN2_005,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),967,22,989,"0,0222446916",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"27,81",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3008,55,3072,"0,0179036458",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"26,48","14,96"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_032,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),1882,23,1912,"0,0120292887",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"25,02","15,35"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3468,63,3538,"0,0178066704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"26,54","14,56"
"low bq, bad alignment, many samples",UPN2_047,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),1134,29,1166,"0,0248713551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"26,19","16,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_035,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),6028,67,6104,"0,0109764089",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"24,96","15,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_036,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),5213,67,5285,"0,0126773888",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"25,11","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_006,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),1532,32,1566,"0,0204342273",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"27,57","14,81"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),1225,22,1249,"0,0176140913",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"25,87",15
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3052,55,3112,"0,0176735219",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"26,5","15,04"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_037,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),5807,72,5890,"0,0122241087",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"25,21","16,97"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3368,61,3433,"0,0177687154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"26,52","16,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3360,69,3438,"0,020069808",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"26,63","15,84"
"low bq, bad alignment, many samples",UPN2_053,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),4969,115,5103,"0,0225357633",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"26,45","15,1"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3207,64,3275,"0,0195419847",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"26,6","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_007,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),7506,133,7650,"0,0173856209",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"27,42","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_008,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),10075,212,10307,"0,0205685456",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"27,56","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_009,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),7845,134,8000,"0,01675",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"27,37","16,15"
"low bq, low freq, many artifacts, many samples",UPN2_010,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),5771,123,5913,"0,0208016235",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"27,34","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_011,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),7381,146,7536,"0,019373673",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"27,49","15,34"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3516,64,3593,"0,017812413",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"26,64","15,23"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_090,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3130,45,3176,"0,0141687657",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"26,21","14,8"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),4318,92,4421,"0,0208097715",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"26,54","16,11"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_058,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),5711,126,5852,"0,0215311005",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"26,43","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_012,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2597,55,2657,"0,0207000376",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"27,45","14,53"
"low bq, bad alignment, many samples",UPN2_060,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),4037,102,4153,"0,0245605586",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"25,03","15,5"
"low bq, low freq, many artifacts, many samples",UPN2_013,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),1971,34,2005,"0,016957606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"27,49","15,03"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_091,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2648,37,2699,"0,013708781",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"26,1","14,95"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_092,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2462,35,2504,"0,0139776358",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"26,36","18,66"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_093,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3240,49,3293,"0,0148800486",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"26,19","15,84"
"low bq, bad alignment, many samples",UPN2_061,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),5521,129,5662,"0,0227834687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"25,32","15,3"
"low bq, bad alignment, many samples",UPN2_062,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3673,85,3764,"0,0225823592",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"25,33","15,85"
"low bq, bad alignment, many samples",UPN2_063,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),4406,116,4530,"0,025607064",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"25,33","15,23"
"low bq, bad alignment, many samples",UPN2_065,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3056,82,3140,"0,0261146497",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"25,08","14,82"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_066,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),9951,206,10169,"0,0202576458",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"25,13","15,41"
"low bq, bad alignment, many samples",UPN2_067,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),12078,293,12401,"0,0236271268",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"25,04","15,11"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_068,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),8081,167,8270,"0,0201934704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"25,27","15,13"
"low bq, bad alignment, many samples",UPN2_069,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),6594,166,6775,"0,024501845",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"25,23","15,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_070,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),4429,95,4530,"0,0209713024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"25,5","15,01"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3276,69,3353,"0,0205785863",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"25,18","15,48"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2251,45,2298,"0,0195822454",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"25,29","14,58"
"low bq, bad alignment, many samples",UPN2_073,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),1674,48,1725,"0,027826087",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"24,84","16,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),4352,91,4456,"0,0204219031",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"25,02","15,26"
"low bq, bad alignment, many samples",UPN2_075,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),5499,144,5653,"0,0254732001",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"25,14","15,43"
"low bq, bad alignment, many samples",UPN2_076,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),5142,132,5285,"0,0249763482",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"25,25","15,03"
"low bq, bad alignment, many samples",UPN2_077,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),7682,206,7912,"0,0260364004",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"25,14","14,82"
"low bq, bad alignment, many samples",UPN2_078,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),5223,120,5348,"0,0224382947",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"25,33","14,97"
"low bq, bad alignment, many samples",UPN2_079,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3496,83,3581,"0,0231778833",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"25,18","15,1"
"low bq, bad alignment, many samples",UPN2_080,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2953,74,3032,"0,0244063325",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"25,01","14,89"
"low bq, bad alignment, many samples",UPN2_081,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),1172,29,1202,"0,0241264559",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"25,01","14,24"
"low bq, bad alignment, many samples",UPN2_082,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),7835,196,8043,"0,0243690165",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"25,19","15,09"
"low bq, bad alignment, many samples",UPN2_083,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),6830,157,7004,"0,0224157624",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"25,16","15,22"
"low bq, bad alignment, many samples",UPN2_084,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),8793,208,9011,"0,0230828987",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"25,27","14,97"
"low bq, bad alignment, many samples",UPN2_085,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),7053,171,7232,"0,0236449115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"24,89","16,08"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),6504,139,6652,"0,0208959711",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"25,27","15,29"
"low bq, bad alignment, many samples",UPN2_087,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),8016,205,8233,"0,0248997935",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"25,24","15,28"
"low bq, bad alignment, many samples",UPN2_088,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),5753,137,5898,"0,023228213",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"25,17","15,85"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_095,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3995,49,4049,"0,0121017535",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"26,07","17,04"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_096,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3521,44,3572,"0,0123180291",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"26,18","15,89"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_097,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3316,44,3366,"0,0130718954",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"26,05","14,5"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_098,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2992,38,3034,"0,0125247198",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"26,12","15,97"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_099,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2101,23,2127,"0,0108133521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"26,29","15,35"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_100,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2266,26,2293,"0,0113388574",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"26,09","16,19"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_101,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3762,52,3818,"0,0136196962",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"26,28","19,27"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_102,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),4102,56,4160,"0,0134615385",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"26,24","17,73"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_103,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2950,31,2985,"0,0103852596",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"26,34",16
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_104,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3573,48,3622,"0,0132523468",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"26,07","14,75"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_105,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2257,31,2292,"0,0135253054",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"26,12",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_106,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),1716,24,1744,"0,0137614679",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"26,15",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_107,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),6410,80,6504,"0,012300123",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"26,23","15,02"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_108,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3757,68,3836,"0,0177267987",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"26,03","14,97"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_109,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),4076,42,4128,"0,0101744186",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"26,24","14,52"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_110,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3601,46,3650,"0,0126027397",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"26,11","15,46"
"low bq, bad alignment, low freq, many artifacts",UPN2_111,7,148529751,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp113Leu/c.338G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),4913,74,4995,"0,0148148148",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-11,Deleterious,2,Damaging,"26,28","15,19"
"low freq, many artifacts",UPN2_047,7,148529760,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met110Lys/c.329T>A|751|EZH2|protein_coding|CODING|ENST00000320356|4|T),2187,39,2240,"0,0174107143",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,"0,001",Damaging,"31,54","29,15"
"low freq, many artifacts",UPN2_049,7,148529760,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met110Lys/c.329T>A|751|EZH2|protein_coding|CODING|ENST00000320356|4|T),2391,25,2422,"0,0103220479",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,1,Damaging,"32,02","27,2"
"low bq, low freq, many artifacts, many samples",UPN2_047,7,148529766,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro108His/c.323C>A|751|EZH2|protein_coding|CODING|ENST00000320356|4|T),2212,24,2241,"0,0107095047",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,85",Deleterious,0,Damaging,"29,35","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_055,7,148529766,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro108His/c.323C>A|751|EZH2|protein_coding|CODING|ENST00000320356|4|T),6815,71,6906,"0,0102809151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,85",Deleterious,0,Damaging,"29,57","18,39"
"low bq, low freq, many artifacts, many samples",UPN2_059,7,148529766,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro108His/c.323C>A|751|EZH2|protein_coding|CODING|ENST00000320356|4|T),1304,22,1332,"0,0165165165",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,85",Deleterious,0,Damaging,"28,09","19,41"
"low bq, low freq, many artifacts, many samples",UPN2_060,7,148529766,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro108His/c.323C>A|751|EZH2|protein_coding|CODING|ENST00000320356|4|T),7804,94,7922,"0,0118656905",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,85",Deleterious,0,Damaging,"27,81","14,19"
"low bq, low freq, many artifacts, many samples",UPN2_061,7,148529766,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro108His/c.323C>A|751|EZH2|protein_coding|CODING|ENST00000320356|4|T),10612,115,10762,"0,0106857461",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,85",Deleterious,0,Damaging,28,"15,96"
"low bq, low freq, many artifacts, many samples",UPN2_062,7,148529766,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro108His/c.323C>A|751|EZH2|protein_coding|CODING|ENST00000320356|4|T),7064,102,7191,"0,0141843972",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,85",Deleterious,0,Damaging,"28,19","15,61"
"low bq, low freq, many artifacts, many samples",UPN2_063,7,148529766,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro108His/c.323C>A|751|EZH2|protein_coding|CODING|ENST00000320356|4|T),8531,106,8654,"0,0122486711",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,85",Deleterious,0,Damaging,"27,94","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_065,7,148529766,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro108His/c.323C>A|751|EZH2|protein_coding|CODING|ENST00000320356|4|T),5849,81,5946,"0,0136226034",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,85",Deleterious,0,Damaging,"27,85","16,32"
"low bq, low freq, many artifacts, many samples",UPN2_066,7,148529766,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro108His/c.323C>A|751|EZH2|protein_coding|CODING|ENST00000320356|4|T),19256,230,19525,"0,0117797695",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,85",Deleterious,0,Damaging,"27,91","15,75"
"low bq, low freq, many artifacts, many samples",UPN2_067,7,148529766,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro108His/c.323C>A|751|EZH2|protein_coding|CODING|ENST00000320356|4|T),23383,308,23760,"0,012962963",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,85",Deleterious,0,Damaging,"27,84","15,75"
"low bq, low freq, many artifacts, many samples",UPN2_068,7,148529766,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro108His/c.323C>A|751|EZH2|protein_coding|CODING|ENST00000320356|4|T),15625,180,15847,"0,0113586168",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,85",Deleterious,0,Damaging,"28,16","15,17"
"low bq, low freq, many artifacts, many samples",UPN2_069,7,148529766,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro108His/c.323C>A|751|EZH2|protein_coding|CODING|ENST00000320356|4|T),12733,160,12922,"0,0123819842",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,85",Deleterious,0,Damaging,"28,05","15,91"
"low bq, low freq, many artifacts, many samples",UPN2_070,7,148529766,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro108His/c.323C>A|751|EZH2|protein_coding|CODING|ENST00000320356|4|T),8512,110,8653,"0,0127123541",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,85",Deleterious,0,Damaging,"28,25","15,65"
"low bq, low freq, many artifacts, many samples",UPN2_071,7,148529766,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro108His/c.323C>A|751|EZH2|protein_coding|CODING|ENST00000320356|4|T),6343,73,6436,"0,0113424487",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,85",Deleterious,0,Damaging,"27,83","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_072,7,148529766,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro108His/c.323C>A|751|EZH2|protein_coding|CODING|ENST00000320356|4|T),4360,57,4430,"0,0128668172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,85",Deleterious,0,Damaging,"28,02","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_073,7,148529766,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro108His/c.323C>A|751|EZH2|protein_coding|CODING|ENST00000320356|4|T),3266,43,3322,"0,0129440096",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,85",Deleterious,0,Damaging,"27,88","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_074,7,148529766,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro108His/c.323C>A|751|EZH2|protein_coding|CODING|ENST00000320356|4|T),8421,100,8552,"0,0116931712",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,85",Deleterious,0,Damaging,"28,09","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_075,7,148529766,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro108His/c.323C>A|751|EZH2|protein_coding|CODING|ENST00000320356|4|T),10664,124,10828,"0,0114517917",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,85",Deleterious,0,Damaging,"27,91","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_076,7,148529766,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro108His/c.323C>A|751|EZH2|protein_coding|CODING|ENST00000320356|4|T),9947,104,10072,"0,0103256553",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,85",Deleterious,0,Damaging,"28,07","16,8"
"low bq, low freq, many artifacts, many samples",UPN2_077,7,148529766,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro108His/c.323C>A|751|EZH2|protein_coding|CODING|ENST00000320356|4|T),14920,180,15133,"0,0118945351",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,85",Deleterious,0,Damaging,"27,91","15,62"
"low bq, low freq, many artifacts, many samples",UPN2_078,7,148529766,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro108His/c.323C>A|751|EZH2|protein_coding|CODING|ENST00000320356|4|T),10089,109,10227,"0,010658062",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,85",Deleterious,0,Damaging,"28,19","15,88"
"low bq, low freq, many artifacts, many samples",UPN2_079,7,148529766,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro108His/c.323C>A|751|EZH2|protein_coding|CODING|ENST00000320356|4|T),6722,74,6815,"0,0108584006",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,85",Deleterious,0,Damaging,"28,1","16,73"
"low bq, low freq, many artifacts, many samples",UPN2_080,7,148529766,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro108His/c.323C>A|751|EZH2|protein_coding|CODING|ENST00000320356|4|T),5748,63,5827,"0,0108117385",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,85",Deleterious,0,Damaging,"27,86",14
"low bq, low freq, many artifacts, many samples",UPN2_081,7,148529766,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro108His/c.323C>A|751|EZH2|protein_coding|CODING|ENST00000320356|4|T),2264,30,2299,"0,0130491518",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,85",Deleterious,0,Damaging,"27,8","15,7"
"low bq, low freq, many artifacts, many samples",UPN2_082,7,148529766,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro108His/c.323C>A|751|EZH2|protein_coding|CODING|ENST00000320356|4|T),15185,177,15406,"0,0114890302",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,85",Deleterious,0,Damaging,"27,87","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_083,7,148529766,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro108His/c.323C>A|751|EZH2|protein_coding|CODING|ENST00000320356|4|T),13180,170,13376,"0,0127093301",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,85",Deleterious,0,Damaging,"28,08","15,91"
"low bq, low freq, many artifacts, many samples",UPN2_084,7,148529766,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro108His/c.323C>A|751|EZH2|protein_coding|CODING|ENST00000320356|4|T),16964,213,17238,"0,0123564219",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,85",Deleterious,0,Damaging,"28,01","15,81"
"low bq, low freq, many artifacts, many samples",UPN2_085,7,148529766,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro108His/c.323C>A|751|EZH2|protein_coding|CODING|ENST00000320356|4|T),13661,197,13910,"0,014162473",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,85",Deleterious,0,Damaging,"27,84","15,71"
"low bq, low freq, many artifacts, many samples",UPN2_086,7,148529766,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro108His/c.323C>A|751|EZH2|protein_coding|CODING|ENST00000320356|4|T),12547,165,12755,"0,0129361035",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,85",Deleterious,0,Damaging,"27,95","16,35"
"low bq, low freq, many artifacts, many samples",UPN2_087,7,148529766,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro108His/c.323C>A|751|EZH2|protein_coding|CODING|ENST00000320356|4|T),15534,186,15774,"0,0117915557",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,85",Deleterious,0,Damaging,"27,9","15,21"
"low bq, low freq, many artifacts",UPN2_088,7,148529766,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro108His/c.323C>A|751|EZH2|protein_coding|CODING|ENST00000320356|4|T),11144,132,11307,"0,0116741841",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,85",Deleterious,0,Damaging,"27,97","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_065,7,148529776,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala105Ser/c.313G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),5847,65,5935,"0,0109519798",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,09",Neutral,253,Tolerated,"28,2","15,68"
"low bq, low freq, many artifacts, many samples",UPN2_067,7,148529776,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala105Ser/c.313G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),23373,265,23711,"0,0111762473",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,09",Neutral,253,Tolerated,"28,27","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_071,7,148529776,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala105Ser/c.313G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),6324,77,6425,"0,0119844358",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,09",Neutral,253,Tolerated,"28,39","16,64"
"low bq, low freq, many artifacts, many samples",UPN2_072,7,148529776,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala105Ser/c.313G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),4367,45,4422,"0,0101763908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,09",Neutral,253,Tolerated,"28,51","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_073,7,148529776,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala105Ser/c.313G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3264,38,3312,"0,01147343",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,09",Neutral,253,Tolerated,"28,24","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_077,7,148529776,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala105Ser/c.313G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),14904,155,15104,"0,0102621822",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,09",Neutral,253,Tolerated,"28,4","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_082,7,148529776,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala105Ser/c.313G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),15139,168,15366,"0,0109332292",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,09",Neutral,253,Tolerated,"28,28","15,17"
"low bq, low freq, many artifacts, many samples",UPN2_085,7,148529776,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala105Ser/c.313G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),13696,144,13884,"0,0103716508",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,09",Neutral,253,Tolerated,"28,3","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_087,7,148529776,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala105Ser/c.313G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),15524,169,15748,"0,0107315215",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,09",Neutral,253,Tolerated,"28,38","14,82"
"low bq, low freq, many artifacts",UPN2_088,7,148529776,C,A,missense_variant(MODERATE|MISSENSE|Gct/Tct|p.Ala105Ser/c.313G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),11125,119,11281,"0,0105487102",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,09",Neutral,253,Tolerated,"28,32","15,18"
"low freq, many artifacts",UPN2_047,7,148529776,C,T,missense_variant(MODERATE|MISSENSE|Gct/Act|p.Ala105Thr/c.313G>A|751|EZH2|protein_coding|CODING|ENST00000320356|4|T),2194,30,2241,"0,0133868809",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,78",Neutral,"0,936",Tolerated,"27,7","33,17"
"low bq, low freq, many artifacts, many samples",UPN2_001,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),4635,89,4738,"0,0187842972",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"31,95",14
"low bq, many samples",UPN2_014,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),6984,184,7185,"0,0256089074",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,84","14,72"
"low bq, many samples",UPN2_015,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),9132,207,9364,"0,0221059376",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,63","14,5"
"low bq, many samples",UPN2_016,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),5100,128,5234,"0,0244554834",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,87","14,27"
"low bq, many samples",UPN2_017,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3442,85,3534,"0,0240520656",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,81","15,2"
"low bq, many samples",UPN2_018,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),4688,123,4826,"0,0254869457",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,73","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_019,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),5252,107,5375,"0,0199069767",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,78","14,37"
"low bq, many samples",UPN2_020,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),4307,115,4427,"0,0259769596",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,58","14,4"
"low bq, many samples",UPN2_021,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),4648,133,4790,"0,0277661795",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,81","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_002,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),6287,99,6396,"0,015478424",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"31,94","14,66"
"low bq, many samples",UPN2_022,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),7478,195,7686,"0,0253708041",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,65","14,54"
"low bq, many samples",UPN2_023,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),8331,206,8554,"0,0240823007",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,62","14,23"
"low bq, many samples",UPN2_024,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3693,109,3813,"0,0285864149",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,65","14,5"
"low bq, many samples",UPN2_025,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),8074,203,8293,"0,0244784758",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,59","14,3"
"low bq, many samples",UPN2_026,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),9097,226,9342,"0,0241918219",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,71","14,57"
"low bq, many samples",UPN2_004,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),655,20,677,"0,0295420975",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"32,11","14,65"
"low bq, many samples",UPN2_027,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),11220,266,11509,"0,0231123469",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,6","14,42"
"low bq, many samples",UPN2_089,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),7541,174,7728,"0,022515528",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"30,02","15,18"
"low bq, many samples",UPN2_042,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2149,73,2228,"0,0327648115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,14","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_028,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),7665,171,7854,"0,0217723453",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,8","14,43"
"low bq, many samples",UPN2_043,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),4449,153,4619,"0,0331240528",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,24","14,89"
"low bq, many samples",UPN2_044,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2503,82,2588,"0,0316846986",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,16","15,01"
"low bq, many samples",UPN2_029,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),8802,214,9034,"0,0236882887",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,56","14,47"
"low bq, many samples",UPN2_030,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),7576,180,7776,"0,0231481481",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,65","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_031,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),4244,91,4350,"0,0209195402",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,69","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_005,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),1853,29,1887,"0,0153683095",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"31,91",14
"low bq, many samples",UPN2_045,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),5639,197,5845,"0,0337040205",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,12","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_032,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3603,80,3694,"0,0216567407",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,53","14,41"
"low bq, many samples",UPN2_046,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),6407,233,6653,"0,0350217947",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,17","14,75"
"low bq, many samples",UPN2_033,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),5911,169,6083,"0,0277823442",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,51","14,48"
"low bq, many samples",UPN2_034,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2504,61,2567,"0,0237631476",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,61",14
"low bq, many samples",UPN2_047,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2144,81,2230,"0,03632287",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"28,58","15,68"
"low bq, many samples",UPN2_035,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),11292,313,11632,"0,0269085282",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,62","14,74"
"low bq, many samples",UPN2_036,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),9804,267,10089,"0,0264644663",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,69","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_006,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2894,59,2961,"0,0199257008",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"31,73","15,22"
"low bq, many samples",UPN2_049,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2325,73,2407,"0,0303282094",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,13","15,36"
"low bq, many samples",UPN2_050,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),5785,179,5990,"0,0298831386",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,09","14,66"
"low bq, many samples",UPN2_037,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),10817,257,11105,"0,0231427285",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,78","14,42"
"low bq, many samples",UPN2_051,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),6291,232,6539,"0,0354794311",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,37","14,94"
"low bq, many samples",UPN2_052,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),6330,220,6570,"0,0334855403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,29","14,74"
"low bq, many samples",UPN2_038,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),13159,340,13527,"0,0251349154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,56","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_039,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),7499,159,7670,"0,0207301173",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,66","14,74"
"low bq, many samples",UPN2_053,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),9326,310,9669,"0,0320612266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,12","15,24"
"low bq, many samples",UPN2_054,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),6031,202,6261,"0,0322632167",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,18","14,76"
"low bq, many samples",UPN2_007,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),14245,327,14598,"0,0224003288",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"31,57","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_008,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),19221,390,19647,"0,0198503588",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"31,78","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_009,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),15027,300,15367,"0,0195223531",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"31,76","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_010,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),11063,233,11314,"0,0205939544",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"31,64","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_011,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),14133,298,14480,"0,0205801105",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"31,68","14,47"
"low bq, many samples",UPN2_055,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),6604,245,6864,"0,0356934732",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,27","14,99"
"low bq, many samples",UPN2_090,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),5954,152,6114,"0,0248609748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"30,08","15,01"
"low bq, many samples",UPN2_057,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),8083,280,8397,"0,0333452423",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,34","14,8"
"low bq, many samples",UPN2_058,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),10703,414,11158,"0,0371034236",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,12","14,66"
"low bq, many samples",UPN2_059,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),1279,39,1320,"0,0295454545",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"30,07","15,9"
"low bq, many samples",UPN2_012,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),4903,114,5030,"0,0226640159",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"31,58","15,54"
"low bq, many samples",UPN2_060,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),7667,184,7876,"0,0233621127",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,97","15,62"
"low bq, many samples",UPN2_040,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),5334,133,5474,"0,0242966752",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,96","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_013,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3743,78,3825,"0,0203921569",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"31,86","14,26"
"low bq, many samples",UPN2_091,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),5036,127,5176,"0,0245363215",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"30,21","15,26"
"low bq, many samples",UPN2_092,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),4725,112,4853,"0,0230785081",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"30,11","15,5"
"low bq, many samples",UPN2_093,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),6133,188,6327,"0,0297139245",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,96","15,56"
"low bq, many samples",UPN2_061,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),10415,256,10705,"0,0239140589",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"30,04","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_062,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),6969,154,7135,"0,0215837421",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"30,1","15,19"
"low bq, many samples",UPN2_063,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),8369,210,8605,"0,024404416",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,99","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_064,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),1820,40,1868,"0,0214132762",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,93","14,82"
"low bq, many samples",UPN2_065,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),5743,143,5907,"0,0242085661",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,91","15,71"
"low bq, many samples",UPN2_066,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),18835,483,19403,"0,0248930578",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,99","15,59"
"low bq, many samples",UPN2_067,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),22907,607,23583,"0,0257388797",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,89","15,66"
"low bq, many samples",UPN2_068,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),15355,353,15748,"0,0224155448",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"30,12","15,29"
"low bq, many samples",UPN2_069,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),12475,317,12825,"0,0247173489",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"30,07","15,86"
"low bq, low freq, many artifacts, many samples",UPN2_070,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),8421,165,8603,"0,019179356",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"30,16","15,54"
"low bq, many samples",UPN2_071,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),6211,146,6380,"0,0228840125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,85","15,73"
"low bq, low freq, many artifacts, many samples",UPN2_072,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),4305,89,4410,"0,0201814059",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"30,09","15,62"
"low bq, many samples",UPN2_073,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3204,81,3295,"0,0245827011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,83","14,81"
"low bq, many samples",UPN2_074,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),8266,212,8496,"0,024952919",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"30,12","14,81"
"low bq, many samples",UPN2_075,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),10409,275,10732,"0,0256243012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,98","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_076,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),9767,198,9999,"0,0198019802",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"30,07","15,6"
"low bq, many samples",UPN2_077,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),14619,345,15022,"0,0229663161",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,98","15,65"
"low bq, many samples",UPN2_078,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),9881,236,10157,"0,0232352072",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"30,13","15,7"
"low bq, low freq, many artifacts, many samples",UPN2_079,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),6612,143,6775,"0,0211070111",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,97","15,21"
"low bq, many samples",UPN2_080,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),5626,136,5781,"0,0235253416",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"30,07","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_081,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),2229,49,2286,"0,0214348206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"30,08","15,2"
"low bq, many samples",UPN2_082,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),14860,391,15288,"0,0255756149",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,92","15,6"
"low bq, many samples",UPN2_083,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),12943,298,13277,"0,0224448294",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"30,12","15,46"
"low bq, many samples",UPN2_084,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),16631,380,17075,"0,0222547584",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"30,02","15,93"
"low bq, many samples",UPN2_085,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),13427,326,13803,"0,023618054",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,91","14,97"
"low bq, many samples",UPN2_086,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),12347,284,12668,"0,0224186928",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,96","15,48"
"low bq, many samples",UPN2_087,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),15248,396,15681,"0,0252534915",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"30,07","15,56"
"low bq, many samples",UPN2_088,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),10903,301,11229,"0,0268055927",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,96","15,82"
"low bq, low freq, many artifacts, many samples",UPN2_094,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),5613,126,5751,"0,0219092332",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"30,08","15,36"
"low bq, many samples",UPN2_095,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),7598,188,7800,"0,0241025641",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"30,05","16,12"
"low bq, many samples",UPN2_096,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),6672,165,6866,"0,0240314594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"30,07","15,57"
"low bq, many samples",UPN2_097,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),6284,147,6446,"0,0228048402",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,94","15,35"
"low bq, many samples",UPN2_098,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),5703,140,5849,"0,0239357155",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,97","15,69"
"low bq, low freq, many artifacts, many samples",UPN2_099,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3976,86,4078,"0,021088769",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"30,29","14,86"
"low bq, many samples",UPN2_100,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),4297,113,4420,"0,0255656109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"30,05","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_101,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),7217,150,7390,"0,0202976996",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"30,16","15,65"
"low bq, many samples",UPN2_102,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),7778,181,7977,"0,0226902344",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,99","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_103,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),5624,112,5745,"0,0194952132",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"30,16","15,29"
"low bq, many samples",UPN2_104,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),6761,171,6947,"0,0246149417",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,99","15,51"
"low bq, low freq, many artifacts, many samples",UPN2_105,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),4366,76,4449,"0,0170824904",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"30,02","15,21"
"low bq, many samples",UPN2_106,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),3278,93,3376,"0,0275473934",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"30,14","15,6"
"low bq, low freq, many artifacts, many samples",UPN2_107,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),12237,246,12504,"0,0196737044",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"30,12","15,58"
"low bq, many samples",UPN2_108,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),7239,176,7435,"0,0236718225",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,95","15,82"
"low bq, low freq, many artifacts, many samples",UPN2_109,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),7758,171,7936,"0,021547379",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"30,2","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_110,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),6873,150,7044,"0,0212947189",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"29,97","15,63"
"low bq, low freq, many artifacts",UPN2_111,7,148529782,C,A,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala103Ser/c.307G>T|751|EZH2|protein_coding|CODING|ENST00000320356|4|A),9411,186,9625,"0,0193246753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,37",Neutral,141,Tolerated,"30,22","14,99"
"low bq, low freq, many artifacts",UPN2_050,7,148529783,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn102Lys/c.306T>A|751|EZH2|protein_coding|CODING|ENST00000320356|4|T),3022,33,3069,"0,0107526882",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,74",Deleterious,56,Tolerated,"33,1","16,27"
"low bq, low freq, many artifacts",UPN2_043,7,148529800,G,T,missense_variant(MODERATE|MISSENSE|Cca/Aca|p.Pro97Thr/c.289C>A|751|EZH2|protein_coding|CODING|ENST00000320356|4|T),2290,24,2319,"0,0103492885",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,-4,Deleterious,192,Tolerated,"33,14","14,92"
"low bq, low freq, many artifacts",UPN2_073,7,148529814,G,T,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro92Gln/c.275C>A|751|EZH2|protein_coding|CODING|ENST00000320356|4|T),1631,23,1655,"0,013897281",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,32",Neutral,241,Tolerated,"32,79","14,96"
"low freq, many artifacts",UPN2_006,7,148529818,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe91Leu/c.271T>C|751|EZH2|protein_coding|CODING|ENST00000320356|4|G),1453,24,1480,"0,0162162162",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,649",Tolerated,"35,06","35,08"
"low bq, low freq, many artifacts",UPN2_050,7,148529823,A,T,stop_gained(HIGH|NONSENSE|tTg/tAg|p.Leu89*/c.266T>A|751|EZH2|protein_coding|CODING|ENST00000320356|4|T),2972,31,3018,"0,0102717031",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,08","20,39"
"low bq, low freq, many artifacts, many samples",UPN2_071,7,148543572,C,A,missense_variant(MODERATE|MISSENSE|gGg/gTg|p.Gly79Val/c.236G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1947,28,1978,"0,0141557128",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,04",Neutral,479,Tolerated,"32,28","16,21"
"low bq, low freq, many artifacts, many samples",UPN2_086,7,148543572,C,A,missense_variant(MODERATE|MISSENSE|gGg/gTg|p.Gly79Val/c.236G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3226,35,3267,"0,0107131925",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,04",Neutral,479,Tolerated,"32,5","18,91"
"low bq, low freq, many artifacts, many samples",UPN2_071,7,148543584,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser75Ile/c.224G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1955,20,1978,"0,0101112235",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,54,Tolerated,"31,77",16
"low bq, low freq, many artifacts",UPN2_080,7,148543584,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser75Ile/c.224G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1580,23,1605,"0,0143302181",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,54,Tolerated,"31,84","17,17"
"inspected, many artifacts",UPN2_047,7,148543588,C,T,missense_variant(MODERATE|MISSENSE|Gtg/Atg|p.Val74Met/c.220G>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),942,32,976,"0,0327868852",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,09",Neutral,"0,128",Tolerated,"34,71","35,38"
"low freq, many artifacts",UPN2_006,7,148543591,A,G,missense_variant(MODERATE|MISSENSE|Tct/Cct|p.Ser73Pro/c.217T>C|751|EZH2|protein_coding|CODING|ENST00000320356|3|G),1902,29,1932,"0,015010352",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,"0,396",Tolerated,"34,77","33,17"
"low bq, low freq, many artifacts, many samples",UPN2_071,7,148543602,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His69Leu/c.206A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1945,24,1974,"0,0121580547",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,65",Deleterious,151,Tolerated,"31,82","17,5"
"low bq, low freq, many artifacts, many samples",UPN2_075,7,148543602,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His69Leu/c.206A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3666,39,3714,"0,0105008078",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,65",Deleterious,151,Tolerated,"31,78","20,59"
"low bq, low freq, many artifacts, many samples",UPN2_077,7,148543602,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His69Leu/c.206A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8948,96,9075,"0,0105785124",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,65",Deleterious,151,Tolerated,"31,93","18,94"
"low bq, low freq, many artifacts",UPN2_084,7,148543602,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His69Leu/c.206A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),9993,110,10153,"0,0108342362",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,65",Deleterious,151,Tolerated,"32,06","18,6"
"low freq, many artifacts",UPN2_090,7,148543602,T,C,missense_variant(MODERATE|MISSENSE|cAc/cGc|p.His69Arg/c.206A>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),2861,32,2900,"0,0110344828",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,64",Deleterious,"0,284",Tolerated,"34,2","33,19"
"low bq, low freq, many artifacts",UPN2_086,7,148543610,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln66His/c.198G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3209,33,3254,"0,0101413645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,413,Tolerated,"31,54","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_062,7,148543612,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln66Glu/c.196C>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),2346,36,2403,"0,0149812734",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,93",Neutral,235,Tolerated,"30,24","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_071,7,148543612,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln66Glu/c.196C>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),1938,21,1964,"0,0106924644",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,93",Neutral,235,Tolerated,"30,07",14
"low bq, low freq, many artifacts, many samples",UPN2_075,7,148543612,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln66Glu/c.196C>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),3654,42,3702,"0,0113452188",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,93",Neutral,235,Tolerated,"29,85",14
"low bq, low freq, many artifacts",UPN2_076,7,148543612,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln66Glu/c.196C>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),3813,44,3871,"0,0113665719",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,93",Neutral,235,Tolerated,"30,46","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_074,7,148543616,C,A,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg64Ser/c.192G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5912,67,5985,"0,0111946533",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,2",Neutral,164,Tolerated,"31,15","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_075,7,148543616,C,A,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg64Ser/c.192G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3656,41,3700,"0,0110810811",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,2",Neutral,164,Tolerated,"31,25","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_084,7,148543616,C,A,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg64Ser/c.192G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),9999,112,10126,"0,011060636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,2",Neutral,164,Tolerated,"31,31","14,31"
"low bq, low freq, many artifacts",UPN2_086,7,148543616,C,A,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg64Ser/c.192G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3207,42,3252,"0,0129151292",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,2",Neutral,164,Tolerated,"31,24","15,9"
"low bq, low freq, many artifacts, many samples",UPN2_066,7,148543617,C,A,missense_variant(MODERATE|MISSENSE|aGg/aTg|p.Arg64Met/c.191G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),6745,81,6828,"0,0118629174",0,0,0,0,1,0,0,0,1,NO,NO,COSM600047. COSM600046,lung,2,NO,NO,NO,NO,NO,NO,"-1,98",Neutral,12,Damaging,"29,98","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_071,7,148543617,C,A,missense_variant(MODERATE|MISSENSE|aGg/aTg|p.Arg64Met/c.191G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1931,33,1964,"0,016802444",0,0,0,0,1,0,0,0,1,NO,NO,COSM600047. COSM600046,lung,2,NO,NO,NO,NO,NO,NO,"-1,98",Neutral,12,Damaging,"29,96","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_076,7,148543617,C,A,missense_variant(MODERATE|MISSENSE|aGg/aTg|p.Arg64Met/c.191G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3818,40,3865,"0,0103492885",0,0,0,0,1,0,0,0,1,NO,NO,COSM600047. COSM600046,lung,2,NO,NO,NO,NO,NO,NO,"-1,98",Neutral,12,Damaging,"30,43","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_077,7,148543617,C,A,missense_variant(MODERATE|MISSENSE|aGg/aTg|p.Arg64Met/c.191G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8947,98,9053,"0,0108251408",0,0,0,0,1,0,0,0,1,NO,NO,COSM600047. COSM600046,lung,2,NO,NO,NO,NO,NO,NO,"-1,98",Neutral,12,Damaging,"30,04","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_083,7,148543617,C,A,missense_variant(MODERATE|MISSENSE|aGg/aTg|p.Arg64Met/c.191G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5483,66,5552,"0,0118876081",0,0,0,0,1,0,0,0,1,NO,NO,COSM600047. COSM600046,lung,2,NO,NO,NO,NO,NO,NO,"-1,98",Neutral,12,Damaging,"30,28","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_086,7,148543617,C,A,missense_variant(MODERATE|MISSENSE|aGg/aTg|p.Arg64Met/c.191G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3211,34,3249,"0,0104647584",0,0,0,0,1,0,0,0,1,NO,NO,COSM600047. COSM600046,lung,2,NO,NO,NO,NO,NO,NO,"-1,98",Neutral,12,Damaging,"30,11","14,38"
"low bq, low freq, many artifacts",UPN2_087,7,148543617,C,A,missense_variant(MODERATE|MISSENSE|aGg/aTg|p.Arg64Met/c.191G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),9959,124,10089,"0,0122906135",0,0,0,0,1,0,0,0,1,NO,NO,COSM600047. COSM600046,lung,2,NO,NO,NO,NO,NO,NO,"-1,98",Neutral,12,Damaging,"30,02","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_074,7,148543620,C,A,missense_variant(MODERATE|MISSENSE|cGa/cTa|p.Arg63Leu/c.188G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5909,61,5978,"0,0102040816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,82",Neutral,997,Tolerated,"29,78","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_086,7,148543620,C,A,missense_variant(MODERATE|MISSENSE|cGa/cTa|p.Arg63Leu/c.188G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3202,33,3247,"0,0101632276",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,82",Neutral,997,Tolerated,"30,05",14
"low bq, low freq, many artifacts, many samples",UPN2_071,7,148543622,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln62His/c.186G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1928,25,1961,"0,0127485977",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,72,Tolerated,"29,89","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_066,7,148543624,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln62Glu/c.184C>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),6730,75,6812,"0,0110099824",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,21",Neutral,814,Tolerated,"28,95","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_071,7,148543624,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln62Glu/c.184C>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),1935,20,1961,"0,0101988781",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,21",Neutral,814,Tolerated,"28,99",15
"low bq, low freq, many artifacts, many samples",UPN2_074,7,148543624,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln62Glu/c.184C>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),5881,70,5966,"0,0117331545",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,21",Neutral,814,Tolerated,"28,81",14
"low bq, low freq, many artifacts, many samples",UPN2_076,7,148543624,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln62Glu/c.184C>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),3801,52,3858,"0,0134784863",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,21",Neutral,814,Tolerated,"29,38","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_077,7,148543624,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln62Glu/c.184C>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),8901,107,9030,"0,0118493909",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,21",Neutral,814,Tolerated,"28,92","14,2"
"low bq, low freq, many artifacts, many samples",UPN2_083,7,148543624,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln62Glu/c.184C>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),5465,64,5540,"0,0115523466",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,21",Neutral,814,Tolerated,29,14
"low bq, low freq, many artifacts, many samples",UPN2_084,7,148543624,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln62Glu/c.184C>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),9976,110,10103,"0,0108878551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,21",Neutral,814,Tolerated,29,"14,12"
"low bq, low freq, many artifacts, many samples",UPN2_086,7,148543624,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln62Glu/c.184C>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),3202,34,3245,"0,0104776579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,21",Neutral,814,Tolerated,"28,88",14
"low bq, low freq, many artifacts",UPN2_087,7,148543624,G,C,missense_variant(MODERATE|MISSENSE|Cag/Gag|p.Gln62Glu/c.184C>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),9944,111,10071,"0,0110217456",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,21",Neutral,814,Tolerated,"28,92","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_062,7,148543625,T,A,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys61Asn/c.183A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2353,29,2398,"0,0120934112",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,76",Neutral,84,Tolerated,"30,51",14
"low bq, low freq, many artifacts, many samples",UPN2_066,7,148543625,T,A,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys61Asn/c.183A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),6689,73,6811,"0,0107179562",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,76",Neutral,84,Tolerated,"30,61","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_075,7,148543625,T,A,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys61Asn/c.183A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3619,48,3692,"0,0130010834",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,76",Neutral,84,Tolerated,"30,42","16,4"
"low bq, low freq, many artifacts, many samples",UPN2_077,7,148543625,T,A,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys61Asn/c.183A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8850,112,9028,"0,0124058485",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,76",Neutral,84,Tolerated,"30,3","15,86"
"low bq, low freq, many artifacts, many samples",UPN2_084,7,148543625,T,A,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys61Asn/c.183A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),9907,117,10098,"0,0115864528",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,76",Neutral,84,Tolerated,"30,38","16,12"
"low bq, low freq, many artifacts",UPN2_086,7,148543625,T,A,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys61Asn/c.183A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3190,35,3245,"0,0107858243",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,76",Neutral,84,Tolerated,"30,35","17,4"
"low bq, low freq, many artifacts, many samples",UPN2_071,7,148543626,T,A,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys61Ile/c.182A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1926,24,1961,"0,0122386537",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,32,Damaging,"31,12",16
"low bq, low freq, many artifacts, many samples",UPN2_075,7,148543626,T,A,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys61Ile/c.182A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3637,42,3691,"0,0113790301",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,32,Damaging,"31,23","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_083,7,148543626,T,A,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys61Ile/c.182A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5444,60,5536,"0,0108381503",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,32,Damaging,"31,52","15,03"
"low bq, low freq, many artifacts",UPN2_084,7,148543626,T,A,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys61Ile/c.182A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),9934,113,10094,"0,0111947692",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,32,Damaging,"31,27","16,45"
"low bq, low freq, many artifacts, many samples",UPN2_071,7,148543628,C,A,missense_variant(MODERATE|MISSENSE|tgG/tgT|p.Trp60Cys/c.180G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1930,24,1961,"0,0122386537",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,29,Damaging,"30,7",14
"low bq, low freq, many artifacts, many samples",UPN2_074,7,148543628,C,A,missense_variant(MODERATE|MISSENSE|tgG/tgT|p.Trp60Cys/c.180G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5885,63,5962,"0,0105669239",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,29,Damaging,"30,64","15,48"
"low bq, low freq, many artifacts, many samples",UPN2_075,7,148543628,C,A,missense_variant(MODERATE|MISSENSE|tgG/tgT|p.Trp60Cys/c.180G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3641,45,3690,"0,012195122",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,29,Damaging,"30,56","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_077,7,148543628,C,A,missense_variant(MODERATE|MISSENSE|tgG/tgT|p.Trp60Cys/c.180G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8891,98,9023,"0,0108611327",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,29,Damaging,"30,89","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_080,7,148543628,C,A,missense_variant(MODERATE|MISSENSE|tgG/tgT|p.Trp60Cys/c.180G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1563,24,1595,"0,0150470219",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,29,Damaging,"30,85","15,58"
"low bq, low freq, many artifacts",UPN2_086,7,148543628,C,A,missense_variant(MODERATE|MISSENSE|tgG/tgT|p.Trp60Cys/c.180G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3188,38,3243,"0,0117175455",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,29,Damaging,"30,71","17,61"
"low bq, low freq, many artifacts",UPN2_075,7,148543629,C,A,missense_variant(MODERATE|MISSENSE|tGg/tTg|p.Trp60Leu/c.179G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3645,38,3690,"0,010298103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,52",Deleterious,138,Tolerated,"30,17","14,68"
"low bq, low freq, many artifacts",UPN2_071,7,148543632,T,A,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu59Val/c.176A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1938,21,1963,"0,0106979114",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,37",Neutral,27,Damaging,"31,89","20,71"
"low bq, low freq, many artifacts, many samples",UPN2_071,7,148543633,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu59*/c.175G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1948,23,1974,"0,0116514691",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,53","15,52"
"low bq, low freq, many artifacts, many samples",UPN2_086,7,148543633,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu59*/c.175G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3226,36,3268,"0,0110159119",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,56","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_076,7,148543634,T,A,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln58His/c.174A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3993,49,4049,"0,0121017535",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,7",Neutral,16,Damaging,"30,16","16,06"
"low bq, low freq, many artifacts, many samples",UPN2_077,7,148543634,T,A,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln58His/c.174A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),9251,113,9391,"0,0120327974",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,7",Neutral,16,Damaging,"29,89","15,81"
"low bq, low freq, many artifacts",UPN2_083,7,148543634,T,A,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln58His/c.174A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5722,64,5802,"0,0110306791",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,7",Neutral,16,Damaging,"29,97","15,86"
"low bq, low freq, many artifacts, many samples",UPN2_062,7,148543635,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln58Leu/c.173A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2967,35,3012,"0,0116201859",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,41,Damaging,"29,26",17
"low bq, many samples",UPN2_065,7,148543635,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln58Leu/c.173A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1089,25,1115,"0,0224215247",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,41,Damaging,"28,87","21,8"
"low bq, low freq, many artifacts, many samples",UPN2_066,7,148543635,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln58Leu/c.173A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8272,85,8391,"0,0101299011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,41,Damaging,"29,02","15,72"
"low bq, low freq, many artifacts, many samples",UPN2_074,7,148543635,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln58Leu/c.173A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7148,83,7254,"0,0114419631",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,41,Damaging,"29,06","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_075,7,148543635,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln58Leu/c.173A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4496,53,4560,"0,011622807",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,41,Damaging,"28,97","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_076,7,148543635,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln58Leu/c.173A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4797,63,4883,"0,0129019046",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,41,Damaging,"29,21","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_077,7,148543635,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln58Leu/c.173A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10853,140,11027,"0,0126961095",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,41,Damaging,"29,07","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_080,7,148543635,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln58Leu/c.173A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1871,20,1898,"0,0105374078",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,41,Damaging,"29,09","16,8"
"low bq, low freq, many artifacts, many samples",UPN2_083,7,148543635,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln58Leu/c.173A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),6903,84,7000,"0,012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,41,Damaging,"28,99","15,31"
"low bq, low freq, many artifacts, many samples",UPN2_084,7,148543635,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln58Leu/c.173A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),12095,138,12266,"0,0112506114",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,41,Damaging,"28,95","16,38"
"low bq, low freq, many artifacts, many samples",UPN2_086,7,148543635,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln58Leu/c.173A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3836,52,3893,"0,013357308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,41,Damaging,"28,91","16,71"
"low bq, low freq, many artifacts",UPN2_087,7,148543635,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln58Leu/c.173A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),12064,156,12249,"0,0127357335",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,41,Damaging,"28,9","16,39"
"low bq, low freq, many artifacts, many samples",UPN2_001,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3879,44,3929,"0,0111987783",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"30,03","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_014,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7983,81,8089,"0,0100135987",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"29,27",14
"low bq, low freq, many artifacts, many samples",UPN2_015,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),12454,131,12601,"0,0103960003",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"29,52","14,9"
"low bq, many samples",UPN2_016,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),8137,189,8345,"0,0226482924",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"28,96","14,19"
"low bq, low freq, many artifacts, many samples",UPN2_017,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5898,99,6008,"0,0164780293",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"29,15","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_018,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),8511,159,8679,"0,018320083",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"29,07","14,3"
"low bq, many samples",UPN2_020,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),8053,198,8270,"0,0239419589",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"28,83","15,32"
"low bq, many samples",UPN2_021,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),9338,220,9581,"0,0229621125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"28,93","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_002,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),9119,157,9294,"0,0168926189",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"29,97","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_022,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7631,152,7811,"0,0194597363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"29,13","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_024,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5329,100,5439,"0,0183857327",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"29,05","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_025,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),13803,236,14066,"0,0167780464",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"29,26","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_026,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),16534,348,16902,"0,0205892794",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"29,23","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_004,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1663,33,1696,"0,0194575472",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"29,96",14
"low bq, low freq, many artifacts, many samples",UPN2_027,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),16605,303,16940,"0,0178866588",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"29,36","14,34"
"low bq, many samples",UPN2_089,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),8132,223,8378,"0,0266173311",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"27,37","15,45"
"low bq, many samples",UPN2_042,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1578,68,1650,"0,0412121212",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"28,91","14,1"
"low bq, low freq, many artifacts, many samples",UPN2_028,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),12078,209,12314,"0,0169725516",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"29,41","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_005,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2140,33,2180,"0,0151376147",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"29,95","14,67"
"low bq, many samples",UPN2_045,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),6466,321,6799,"0,0472128254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"28,98","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_032,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3418,40,3465,"0,0115440115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"29,56","14,35"
"low bq, many samples",UPN2_046,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7369,315,7710,"0,0408560311",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"28,96","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_033,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),9377,183,9575,"0,0191122715",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"29,04","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_034,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3891,75,3976,"0,0188631791",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"29,49","14,97"
"low bq, many samples",UPN2_047,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1685,70,1757,"0,0398406375",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"28,82","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_036,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),10274,107,10403,"0,0102854946",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"29,63","15,5"
"low bq, low freq, many artifacts, many samples",UPN2_006,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3410,68,3481,"0,0195346165",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"29,85","15,1"
"low bq, many samples",UPN2_049,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),630,30,663,"0,0452488688",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"28,9","15,57"
"low bq, low freq, many artifacts, many samples",UPN2_037,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),15479,281,15801,"0,0177836846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"29,25","14,42"
"low bq, many samples",UPN2_051,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),6889,307,7216,"0,0425443459",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"28,93","14,52"
"low bq, many samples",UPN2_052,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),13952,638,14628,"0,043614985",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"29,15","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_038,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),19722,345,20097,"0,0171667413",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"29,22","14,22"
"low bq, many samples",UPN2_053,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),19205,862,20124,"0,0428344266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"28,98","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_007,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),13824,193,14054,"0,0137327451",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"29,78","15,17"
"low bq, low freq, many artifacts, many samples",UPN2_008,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),20299,278,20623,"0,013480095",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"29,81","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_009,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),21120,343,21498,"0,0159549726",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"29,73","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_010,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),11016,168,11200,"0,015",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"29,8","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_011,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),9125,137,9278,"0,0147661134",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"29,54","14,76"
"low bq, many samples",UPN2_055,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),6524,282,6826,"0,0413126282",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"28,93","14,18"
"low bq, bad alignment, many samples",UPN2_090,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4812,341,5172,"0,0659319412",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"26,49","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_012,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5303,107,5429,"0,0197089703",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"29,74","15,9"
"low bq, low freq, many artifacts, many samples",UPN2_040,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),10499,200,10715,"0,0186654223",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"29,25","14,07"
"low bq, low freq, many artifacts, many samples",UPN2_013,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4432,80,4530,"0,0176600442",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"29,4","15,19"
"low bq, bad alignment, many samples",UPN2_091,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),6344,478,6849,"0,0697912104",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"26,04","14,65"
"low bq, bad alignment, many samples",UPN2_092,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4069,243,4327,"0,0561590016",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"26,79","14,44"
"low bq, many samples",UPN2_093,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5232,130,5379,"0,024168061",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"27,58","14,65"
"low bq, many samples",UPN2_061,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1373,38,1421,"0,0267417312",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"27,63","14,34"
"low bq, bad alignment, many samples",UPN2_062,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4004,208,4243,"0,0490219185",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"25,72","14,79"
"low bq, bad alignment, many samples",UPN2_065,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Gaa|p.Gln58Glu/c.172C>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),1529,92,1648,"0,0558252427",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"25,45","15,3"
"low bq, bad alignment, many samples",UPN2_066,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),11344,597,12080,"0,0494205298",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"25,54","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_067,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1253,26,1287,"0,0202020202",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"27,03","14,54"
"low bq, many samples",UPN2_068,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2125,55,2194,"0,0250683683",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"27,19","14,56"
"low bq, many samples",UPN2_069,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2669,82,2771,"0,029592205",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"27,44","14,76"
"low bq, bad alignment, many samples",UPN2_070,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),828,27,862,"0,0313225058",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"26,82","15,22"
"low bq, bad alignment, many samples",UPN2_071,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3200,185,3421,"0,054077755",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"25,46","15,25"
"low bq, bad alignment, many samples",UPN2_073,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1451,66,1532,"0,0430809399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"25,39","14,79"
"low bq, bad alignment, many samples",UPN2_074,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),9831,541,10470,"0,0516714422",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"25,57","14,78"
"low bq, bad alignment, many samples",UPN2_075,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),6051,365,6482,"0,0563097809",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"25,27","14,55"
"low bq, bad alignment, many samples",UPN2_076,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),6422,350,6848,"0,0511098131",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"25,86","14,74"
"low bq, bad alignment, many samples",UPN2_077,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),14941,847,15971,"0,0530336234",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"25,58","14,8"
"low bq, bad alignment, many samples",UPN2_080,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2616,156,2797,"0,0557740436",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"25,57","14,81"
"low bq, bad alignment, many samples",UPN2_083,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),9158,516,9785,"0,0527337762",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"25,87","14,81"
"low bq, bad alignment, many samples",UPN2_084,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),16662,929,17785,"0,0522350295",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"25,59","14,74"
"low bq, bad alignment, many samples",UPN2_086,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5305,300,5668,"0,0529287227",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"25,68","14,9"
"low bq, bad alignment, many samples",UPN2_087,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),16573,1017,17768,"0,0572377308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"25,51","14,78"
"low bq, many samples",UPN2_094,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),6721,255,6994,"0,0364598227",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"27,29","14,77"
"low bq, bad alignment, many samples",UPN2_095,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),8704,550,9290,"0,0592034446",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"26,64","14,71"
"low bq, many samples",UPN2_096,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),6389,172,6591,"0,0260961918",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"27,53","14,65"
"low bq, many samples",UPN2_097,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4083,186,4290,"0,0433566434",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"27,03","14,86"
"low bq, bad alignment, many samples",UPN2_099,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5556,412,5988,"0,0688042752",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"26,31","14,77"
"low bq, many samples",UPN2_100,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5320,142,5484,"0,0258935084",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"27,68","14,56"
"low bq, bad alignment, many samples",UPN2_101,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),8139,398,8571,"0,0464356551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"26,93","14,74"
"low bq, many samples",UPN2_102,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7842,219,8088,"0,0270771513",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"27,62","14,71"
"low bq, many samples",UPN2_103,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7820,417,8270,"0,0504232164",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"27,02","14,54"
"low bq, bad alignment, many samples",UPN2_104,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),8922,482,9438,"0,051070142",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"26,85","14,65"
"low bq, many samples",UPN2_105,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1805,56,1871,"0,0299305184",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"27,49","14,12"
"low bq, bad alignment, many samples",UPN2_106,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2495,175,2679,"0,0653228817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"26,22","14,81"
"low bq, bad alignment, many samples",UPN2_107,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),13638,818,14511,"0,0563710289",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"26,52","14,8"
"low bq, bad alignment, many samples",UPN2_108,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),10123,571,10728,"0,0532252051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"26,8","14,96"
"low bq, many samples",UPN2_109,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),10207,247,10486,"0,0235552165",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"27,66","14,83"
"low bq, bad alignment, many samples",UPN2_110,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),9893,528,10469,"0,0504346165",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"26,58","14,81"
"low bq, bad alignment",UPN2_111,7,148543636,G,T,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln58Lys/c.172C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),10920,630,11583,"0,0543900544",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,24",Neutral,496,Tolerated,"26,82","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_066,7,148543637,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn57Lys/c.171C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),12406,132,12643,"0,01044056",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,34",Neutral,171,Tolerated,"27,11","14,37"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,7,148543637,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn57Lys/c.171C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1579,20,1616,"0,0123762376",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,34",Neutral,171,Tolerated,"26,95","15,3"
"inspected, many artifacts, bad alignment",UPN2_049,7,148543637,GT,G,frameshift_variant(HIGH||aac/|p.Asn57fs/c.170delA|751|EZH2|protein_coding|CODING|ENST00000320356|3|G),684,21,713,"0,0294530154",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,86",NA
"low bq, low freq, many artifacts, many samples",UPN2_062,7,148543638,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn57Thr/c.170A>C|751|EZH2|protein_coding|CODING|ENST00000320356|3|G),4359,45,4480,"0,0100446429",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,36",Neutral,15,Damaging,"27,36","16,16"
"low bq, low freq, many artifacts, many samples",UPN2_073,7,148543638,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn57Thr/c.170A>C|751|EZH2|protein_coding|CODING|ENST00000320356|3|G),1578,24,1628,"0,0147420147",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,36",Neutral,15,Damaging,"27,78","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_076,7,148543638,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn57Thr/c.170A>C|751|EZH2|protein_coding|CODING|ENST00000320356|3|G),7027,74,7215,"0,0102564103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,36",Neutral,15,Damaging,"27,74","15,82"
"low bq, low freq, many artifacts",UPN2_084,7,148543638,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn57Thr/c.170A>C|751|EZH2|protein_coding|CODING|ENST00000320356|3|G),18403,205,18867,"0,0108655324",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,36",Neutral,15,Damaging,"27,64","15,45"
"low bq, low freq, many artifacts, many samples",UPN2_042,7,148543641,A,T,stop_gained(HIGH|NONSENSE|tTa/tAa|p.Leu56*/c.167T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1718,27,1750,"0,0154285714",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,83","15,89"
"low bq, low freq, many artifacts, many samples",UPN2_046,7,148543641,A,T,stop_gained(HIGH|NONSENSE|tTa/tAa|p.Leu56*/c.167T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),8005,132,8177,"0,0161428397",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,8","21,09"
"low bq, low freq, many artifacts, many samples",UPN2_047,7,148543641,A,T,stop_gained(HIGH|NONSENSE|tTa/tAa|p.Leu56*/c.167T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1829,23,1858,"0,012378902",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,72","18,78"
"low bq, low freq, many artifacts, many samples",UPN2_051,7,148543641,A,T,stop_gained(HIGH|NONSENSE|tTa/tAa|p.Leu56*/c.167T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7519,83,7631,"0,0108766872",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,71","16,17"
"low bq, low freq, many artifacts, many samples",UPN2_052,7,148543641,A,T,stop_gained(HIGH|NONSENSE|tTa/tAa|p.Leu56*/c.167T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),15245,161,15474,"0,0104045496",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,88","15,61"
"low bq, low freq, many artifacts, many samples",UPN2_053,7,148543641,A,T,stop_gained(HIGH|NONSENSE|tTa/tAa|p.Leu56*/c.167T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),20978,251,21307,"0,0117801661",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,75","16,35"
"low bq, low freq, many artifacts, many samples",UPN2_055,7,148543641,A,T,stop_gained(HIGH|NONSENSE|tTa/tAa|p.Leu56*/c.167T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7084,106,7217,"0,0146875433",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,74","17,64"
"low bq, low freq, many artifacts, many samples",UPN2_013,7,148543641,A,T,stop_gained(HIGH|NONSENSE|tTa/tAa|p.Leu56*/c.167T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4722,57,4782,"0,0119196989",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,89","17,47"
"low bq, low freq, many artifacts, many samples",UPN2_073,7,148543641,A,T,stop_gained(HIGH|NONSENSE|tTa/tAa|p.Leu56*/c.167T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1609,24,1634,"0,0146878825",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,22","17,12"
"low bq, low freq, many artifacts, many samples",UPN2_080,7,148543641,A,T,stop_gained(HIGH|NONSENSE|tTa/tAa|p.Leu56*/c.167T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2929,37,2987,"0,0123870104",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,67","18,65"
"low bq, low freq, many artifacts",UPN2_084,7,148543641,A,T,stop_gained(HIGH|NONSENSE|tTa/tAa|p.Leu56*/c.167T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),18642,200,18908,"0,0105775333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,49","18,61"
"low bq, many samples",UPN2_062,7,148543643,G,T,missense_variant(MODERATE|MISSENSE|atC/atG|p.Ile55Met/c.165C>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),4336,115,4498,"0,0255669186",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,0,Neutral,1,Tolerated,"28,32","14,11"
"low bq, many samples",UPN2_074,7,148543643,G,T,missense_variant(MODERATE|MISSENSE|atC/atG|p.Ile55Met/c.165C>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),10697,339,11166,"0,0303600215",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,0,Neutral,1,Tolerated,"28,24","14,4"
"low bq, many samples",UPN2_080,7,148543643,G,T,missense_variant(MODERATE|MISSENSE|atC/atG|p.Ile55Met/c.165C>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),2872,81,2987,"0,0271175092",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,0,Neutral,1,Tolerated,"28,01","14,47"
low bq,UPN2_083,7,148543643,G,T,missense_variant(MODERATE|MISSENSE|atC/atG|p.Ile55Met/c.165C>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),9984,287,10394,"0,0276120839",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,0,Neutral,1,Tolerated,"28,39","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_014,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),8023,88,8131,"0,010822777",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"31,2","17,77"
"low bq, low freq, many artifacts, many samples",UPN2_016,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),8545,109,8677,"0,0125619454",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"30,58","16,29"
"low bq, low freq, many artifacts, many samples",UPN2_018,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),8882,118,9020,"0,0130820399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"30,57","17,28"
"low bq, low freq, many artifacts, many samples",UPN2_020,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),8680,134,8861,"0,0151224467",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"29,92","16,51"
"low bq, low freq, many artifacts, many samples",UPN2_021,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),10053,144,10233,"0,0140721196",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"30,14","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_002,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),9619,131,9783,"0,0133905755",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"31,25","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_022,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),8110,114,8263,"0,013796442",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"30,15","15,42"
"low bq, low freq, many artifacts, many samples",UPN2_023,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),9107,100,9242,"0,0108201688",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"31,31","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_024,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5603,78,5698,"0,0136890137",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"30,43","16,79"
"low bq, low freq, many artifacts, many samples",UPN2_025,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),14419,191,14664,"0,0130250955",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"30,57","17,01"
"low bq, low freq, many artifacts, many samples",UPN2_026,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),17685,225,17966,"0,0125236558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"30,06","15,8"
"low bq, low freq, many artifacts, many samples",UPN2_004,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1757,23,1783,"0,0128996074",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"30,95","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_027,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),17389,193,17653,"0,0109329859",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"30,54","16,2"
"low bq, many samples",UPN2_042,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1706,39,1753,"0,0222475756",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"29,71","22,82"
"low bq, low freq, many artifacts, many samples",UPN2_028,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),12662,133,12852,"0,0103485839",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"30,53","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_029,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),9529,101,9680,"0,0104338843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"31,46","16,66"
"low bq, low freq, many artifacts, many samples",UPN2_005,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2271,36,2316,"0,0155440415",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"31,01","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_045,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7065,116,7225,"0,0160553633",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"29,7","15,72"
"low bq, low freq, many artifacts, many samples",UPN2_046,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),8009,137,8190,"0,0167277167",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"29,47","16,3"
"low bq, low freq, many artifacts, many samples",UPN2_033,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),9808,129,9959,"0,0129531077",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"30,55","17,83"
"low bq, low freq, many artifacts, many samples",UPN2_034,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4050,44,4110,"0,0107055961",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"30,84","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_047,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1831,23,1861,"0,0123589468",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"29,27","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_006,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3665,53,3731,"0,0142053069",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"30,96","16,25"
"low bq, low freq, many artifacts, many samples",UPN2_037,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),16196,206,16447,"0,0125250806",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"30,56","16,27"
"low bq, low freq, many artifacts, many samples",UPN2_051,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7480,138,7641,"0,0180604633",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"29,63","16,51"
"low bq, low freq, many artifacts, many samples",UPN2_052,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),15205,243,15507,"0,0156703424",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"29,53","15,95"
"low bq, low freq, many artifacts, many samples",UPN2_038,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),20649,232,20961,"0,0110681742",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"30,39","16,22"
"low bq, low freq, many artifacts, many samples",UPN2_053,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),20922,361,21352,"0,0169070813",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"29,51","16,46"
"low bq, low freq, many artifacts, many samples",UPN2_007,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),13949,145,14141,"0,0102538717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"32,09","15,79"
"low bq, low freq, many artifacts, many samples",UPN2_008,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),20464,221,20741,"0,010655224",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"32,18","16,79"
"low bq, low freq, many artifacts, many samples",UPN2_009,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),22058,301,22461,"0,0134010062",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"31,3","16,25"
"low bq, low freq, many artifacts, many samples",UPN2_055,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7051,119,7226,"0,0164683089",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"29,6","15,45"
"low bq, low freq, many artifacts, many samples",UPN2_012,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5691,90,5796,"0,0155279503",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"31,04","16,49"
"low bq, low freq, many artifacts, many samples",UPN2_040,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),11015,155,11216,"0,0138195435",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"30,54","16,77"
"low bq, low freq, many artifacts, many samples",UPN2_013,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4689,59,4790,"0,0123173278",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"30,88","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_062,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4422,61,4506,"0,0135375055",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"28,34","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_065,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1721,23,1753,"0,0131203651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"28,25","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_066,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),12594,154,12818,"0,0120143548",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"28,21","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_069,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2748,28,2793,"0,0100250627",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"30,3","18,57"
"low bq, low freq, many artifacts, many samples",UPN2_071,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3609,45,3667,"0,0122716117",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"28,02","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_074,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),10981,123,11180,"0,0110017889",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"28,19","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_075,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),6790,85,6908,"0,0123045744",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"28,39","15,34"
"low bq, low freq, many artifacts, many samples",UPN2_076,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7124,80,7247,"0,0110390506",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"28,45","15,82"
"low bq, low freq, many artifacts, many samples",UPN2_077,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),16609,215,16937,"0,0126941017",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"28,28","15,93"
"low bq, low freq, many artifacts, many samples",UPN2_080,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2932,32,2989,"0,0107059217",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"28,36","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_083,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),10236,126,10408,"0,0121060723",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"28,37","16,21"
"low bq, low freq, many artifacts, many samples",UPN2_084,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),18592,232,18944,"0,0122466216",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"28,09","15,61"
"low bq, low freq, many artifacts, many samples",UPN2_086,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5947,74,6057,"0,0122172693",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"28,27","15,61"
"low bq, low freq, many artifacts",UPN2_087,7,148543644,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),18573,244,18920,"0,0128964059",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,192,Tolerated,"28,14","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_042,7,148543645,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile55Phe/c.163A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1722,26,1760,"0,0147727273",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,"0,44",Tolerated,"29,79",14
"low bq, low freq, many artifacts, many samples",UPN2_045,7,148543645,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile55Phe/c.163A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7080,113,7244,"0,0155991165",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,"0,44",Tolerated,"29,75",15
"low bq, low freq, many artifacts, many samples",UPN2_046,7,148543645,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile55Phe/c.163A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8043,129,8216,"0,0157010711",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,"0,44",Tolerated,"29,87","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_047,7,148543645,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile55Phe/c.163A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1827,36,1865,"0,0193029491",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,"0,44",Tolerated,"29,74","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_051,7,148543645,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile55Phe/c.163A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7492,125,7652,"0,0163355985",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,"0,44",Tolerated,30,"14,76"
"low bq, low freq, many artifacts, many samples",UPN2_052,7,148543645,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile55Phe/c.163A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),15255,197,15551,"0,0126679956",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,"0,44",Tolerated,"29,82","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_053,7,148543645,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile55Phe/c.163A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),20998,329,21419,"0,0153601942",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,"0,44",Tolerated,"29,83","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_055,7,148543645,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile55Phe/c.163A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7106,110,7243,"0,0151870772",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,"0,44",Tolerated,"30,01","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_062,7,148543645,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile55Phe/c.163A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4454,58,4523,"0,0128233473",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,"0,44",Tolerated,"28,74","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_065,7,148543645,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile55Phe/c.163A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1724,24,1755,"0,0136752137",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,"0,44",Tolerated,"28,87","17,5"
"low bq, low freq, many artifacts, many samples",UPN2_066,7,148543645,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile55Phe/c.163A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),12593,188,12851,"0,0146292117",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,"0,44",Tolerated,"28,94","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_068,7,148543645,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile55Phe/c.163A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2178,33,2213,"0,0149118843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,"0,44",Tolerated,"30,24",14
"low bq, low freq, many artifacts, many samples",UPN2_071,7,148543645,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile55Phe/c.163A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3611,51,3679,"0,0138624626",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,"0,44",Tolerated,"28,88","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_074,7,148543645,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile55Phe/c.163A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10999,158,11208,"0,0140970735",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,"0,44",Tolerated,"28,76","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_075,7,148543645,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile55Phe/c.163A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),6770,114,6926,"0,016459717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,"0,44",Tolerated,"29,1","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_076,7,148543645,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile55Phe/c.163A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7134,97,7267,"0,0133480116",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,"0,44",Tolerated,"28,84","14,13"
"low bq, low freq, many artifacts, many samples",UPN2_077,7,148543645,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile55Phe/c.163A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),16627,247,16974,"0,0145516673",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,"0,44",Tolerated,"28,82","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_080,7,148543645,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile55Phe/c.163A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2955,32,2999,"0,0106702234",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,"0,44",Tolerated,"28,81",14
"low bq, low freq, many artifacts, many samples",UPN2_083,7,148543645,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile55Phe/c.163A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10232,147,10425,"0,0141007194",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,"0,44",Tolerated,"28,79","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_084,7,148543645,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile55Phe/c.163A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),18616,280,18982,"0,0147508166",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,"0,44",Tolerated,"28,79","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_086,7,148543645,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile55Phe/c.163A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5977,74,6072,"0,0121870883",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,"0,44",Tolerated,"28,91","14,42"
"low bq, low freq, many artifacts",UPN2_087,7,148543645,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile55Phe/c.163A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),18638,263,18965,"0,0138676509",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,"0,44",Tolerated,"28,9","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_071,7,148543646,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu54Asp/c.162A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3621,42,3682,"0,0114068441",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,337,Tolerated,"29,82",18
"low bq, low freq, many artifacts, many samples",UPN2_075,7,148543646,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu54Asp/c.162A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),6838,78,6930,"0,0112554113",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,337,Tolerated,"30,02","16,15"
"low bq, low freq, many artifacts, many samples",UPN2_089,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8309,88,8435,"0,0104327208",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,82","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_042,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1728,28,1762,"0,0158910329",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,23",14
"low bq, low freq, many artifacts, many samples",UPN2_045,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7066,120,7252,"0,0165471594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,88","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_046,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8070,121,8231,"0,0147005224",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,94","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_047,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1812,37,1867,"0,0198178897",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,99","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_006,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3692,38,3742,"0,0101549973",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,72",14
"low bq, low freq, many artifacts, many samples",UPN2_051,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7466,135,7665,"0,0176125245",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,04","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_052,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),15211,258,15569,"0,0165713919",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,15","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_053,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),20969,343,21456,"0,0159862043",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,08","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_009,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),22163,273,22524,"0,0121204049",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,06","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_055,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7084,113,7251,"0,0155840574",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,21","14,65"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_090,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5271,119,5411,"0,021992238",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,13","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_058,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1053,21,1079,"0,0194624652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,32",14
"low bq, low freq, many artifacts, many samples",UPN2_012,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5715,66,5812,"0,0113558156",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,46",14
"low bq, low freq, many artifacts, many samples",UPN2_013,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4692,76,4795,"0,0158498436",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,86","15,46"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_091,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7067,149,7241,"0,0205772683",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,54","14,77"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_092,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4393,76,4490,"0,0169265033",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,54","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_093,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5331,60,5412,"0,0110864745",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,32","15,18"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4426,72,4528,"0,0159010601",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,13","14,64"
"low bq, bad alignment, many samples",UPN2_065,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1707,40,1756,"0,0227790433",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,46","14,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_066,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),12472,269,12859,"0,0209192006",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,86","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_067,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1270,25,1299,"0,0192455735",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,77","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_068,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2171,30,2214,"0,0135501355",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,87","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_069,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2734,45,2796,"0,0160944206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,03",14
"low bq, bad alignment, many samples",UPN2_071,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3568,86,3682,"0,0233568713",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,88","14,23"
"low bq, bad alignment, many samples",UPN2_073,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1589,43,1642,"0,0261875761",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,96",14
"low bq, bad alignment, many samples",UPN2_074,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10882,282,11220,"0,0251336898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,96","14,91"
"low bq, bad alignment, many samples",UPN2_075,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),6692,178,6921,"0,0257188268",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,9","14,46"
"low bq, bad alignment, many samples",UPN2_076,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7066,169,7273,"0,0232366286",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,05","14,66"
"low bq, bad alignment, many samples",UPN2_077,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),16490,393,16991,"0,0231298923",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,84","14,54"
"low bq, bad alignment, many samples",UPN2_080,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2910,82,3002,"0,0273151233",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,68","17,16"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10136,219,10435,"0,0209870628",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,04","14,17"
"low bq, bad alignment, many samples",UPN2_084,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),18409,443,18993,"0,0233243827",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,92","14,73"
"low bq, bad alignment, many samples",UPN2_086,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5909,141,6082,"0,0231831634",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,97","14,18"
"low bq, bad alignment, many samples",UPN2_087,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),18399,437,18973,"0,0230327307",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,73","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_094,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),6978,88,7095,"0,0124031008",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,59","14,5"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_095,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),9457,172,9666,"0,0177943306",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,48","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_097,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4325,64,4409,"0,0145157632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,17","14,69"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_099,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),6213,117,6358,"0,0184020132",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,43","14,33"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_101,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8739,129,8911,"0,0144764897",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,65","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_102,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8015,82,8133,"0,0100823804",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,12","14,48"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_103,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8421,139,8591,"0,016179723",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,7","14,6"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_104,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),9645,134,9829,"0,0136331265",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,55","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_105,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1874,23,1901,"0,0120988953",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,47",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_106,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2759,55,2837,"0,0193866761",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,6","14,6"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_107,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),14860,230,15166,"0,0151655018",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,34","14,87"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_108,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10927,170,11157,"0,0152370709",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,6","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_109,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10412,111,10558,"0,0105133548",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,27","14,94"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_110,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10622,173,10837,"0,0159638276",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,55","14,57"
"low bq, bad alignment, low freq, many artifacts",UPN2_111,7,148543648,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu54*/c.160G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),11819,188,12065,"0,0155822627",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,43","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_004,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1762,28,1793,"0,0156162856",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"29,96",14
"low bq, low freq, many artifacts, many samples",UPN2_089,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),8269,115,8405,"0,0136823319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"27,35","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_042,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1731,23,1765,"0,0130311615",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"27,52","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_045,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7135,97,7267,"0,0133480116",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"27,67","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_046,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),8071,124,8242,"0,015044892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"27,65","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_047,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1842,21,1869,"0,0112359551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"27,6","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_006,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3694,43,3744,"0,0114850427",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"29,76","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_051,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7517,123,7678,"0,0160197968",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"27,68","15,37"
"low bq, low freq, many artifacts, many samples",UPN2_052,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),15303,223,15597,"0,0142976213",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"27,74","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_053,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),21060,333,21491,"0,0154948583",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"27,57","16,01"
"low bq, low freq, many artifacts, many samples",UPN2_009,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),22269,227,22553,"0,0100651798",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"30,32","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_055,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7108,117,7257,"0,0161223646",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"27,81","16,5"
"low bq, bad alignment, many samples",UPN2_090,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aGg|p.Thr53Arg/c.158C>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),5136,128,5323,"0,0240465903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"24,87","15,63"
"low bq, low freq, many artifacts, many samples",UPN2_012,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5742,60,5820,"0,0103092784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"29,73","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_013,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4703,67,4789,"0,0139903947",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"29,95","14,73"
"low bq, bad alignment, many samples",UPN2_091,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7028,194,7251,"0,0267549304",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"24,62","15,57"
"low bq, bad alignment, many samples",UPN2_092,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4382,100,4495,"0,022246941",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"25,52","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_093,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5326,69,5415,"0,0127423823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"27,72","15,59"
"low bq, low freq, many artifacts, many samples",UPN2_061,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1401,25,1439,"0,0173731758",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"27,74","15,92"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4401,97,4531,"0,0214080777",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"25,38","15,78"
"low bq, bad alignment, many samples",UPN2_065,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1694,48,1758,"0,0273037543",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"25,31","17,35"
"low bq, bad alignment, many samples",UPN2_066,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),12488,291,12885,"0,0225844005",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"25,35","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_067,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1273,22,1301,"0,0169100692",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"27,89",16
"low bq, low freq, many artifacts, many samples",UPN2_068,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2174,31,2218,"0,0139765555",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"28,1","16,13"
"low bq, low freq, many artifacts, many samples",UPN2_069,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2746,34,2798,"0,0121515368",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"28,1","14,91"
"low bq, bad alignment, many samples",UPN2_071,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3535,115,3685,"0,0312075984",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"25,12","16,1"
"low bq, bad alignment, many samples",UPN2_073,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1594,45,1644,"0,0273722628",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"25,25","14,29"
"low bq, bad alignment, many samples",UPN2_074,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),10885,260,11245,"0,0231213873",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"25,07",16
"low bq, bad alignment, many samples",UPN2_075,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),6686,156,6892,"0,0226349391",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"25,1","15,81"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7066,144,7278,"0,0197856554",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"25,54","14,72"
"low bq, bad alignment, many samples",UPN2_077,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),16450,387,17014,"0,0227459739",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"25,23","14,55"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2915,55,3004,"0,0183089214",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"25,19","15,27"
"low bq, bad alignment, many samples",UPN2_083,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),10120,230,10436,"0,0220390954",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"25,48","15,1"
"low bq, bad alignment, many samples",UPN2_084,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),18329,445,19023,"0,0233927351",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"25,39","15,24"
"low bq, bad alignment, many samples",UPN2_086,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5874,147,6077,"0,0241895672",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"25,25","14,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_087,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),18412,417,19000,"0,0219473684",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"25,18","15,06"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_094,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),6962,117,7093,"0,016495136",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"26,92","15,08"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_095,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),9419,207,9674,"0,0213975605",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"25,51","15,92"
"low bq, low freq, many artifacts, many samples",UPN2_096,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),6542,88,6643,"0,0132470269",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"27,53","17,7"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_097,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4294,76,4401,"0,0172688025",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"26,38","17,7"
"low bq, bad alignment, many samples",UPN2_099,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),6178,172,6368,"0,0270100503",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"24,43","16,16"
"low bq, low freq, many artifacts, many samples",UPN2_100,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5425,91,5526,"0,0164676077",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"27,65","14,73"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_101,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),8710,167,8911,"0,0187408821",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"25,89","15,41"
"low bq, low freq, many artifacts, many samples",UPN2_102,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7996,108,8133,"0,0132792328",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"27,46","14,74"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_103,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),8376,175,8583,"0,0203891413",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"25,87","16,07"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_104,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),9590,205,9834,"0,0208460443",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"25,68","15,88"
"low bq, low freq, many artifacts, many samples",UPN2_105,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1862,26,1895,"0,0137203166",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"27,04","15,88"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_106,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2764,60,2837,"0,0211491012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"24,45","15,37"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_107,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),14783,322,15156,"0,0212457113",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"25,35","15,88"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_108,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),10883,218,11157,"0,0195393027",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"25,74","16,22"
"low bq, low freq, many artifacts, many samples",UPN2_109,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),10389,144,10557,"0,0136402387",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"27,75","15,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_110,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),10587,211,10834,"0,0194757246",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"25,72","16,26"
"low bq, bad alignment, low freq, many artifacts",UPN2_111,7,148543650,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr53Lys/c.158C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),11774,250,12066,"0,0207193768",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,34,Damaging,"25,72","15,7"
"low bq, low freq, many artifacts, many samples",UPN2_018,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8928,100,9055,"0,0110436223",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"29,09","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_020,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8740,121,8904,"0,013589398",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"28,38","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_021,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10137,117,10285,"0,01137579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"28,33","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_002,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),9685,106,9820,"0,0107942974",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"30,51","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_022,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8185,84,8294,"0,0101278032",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"28,58","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_004,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1762,26,1794,"0,0144927536",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"30,26",15
"low bq, low freq, many artifacts, many samples",UPN2_042,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1726,31,1768,"0,0175339367",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"28,93",14
"low bq, low freq, many artifacts, many samples",UPN2_005,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2289,29,2328,"0,0124570447",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"30,36",14
"low bq, low freq, many artifacts, many samples",UPN2_045,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7101,138,7272,"0,0189768977",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"28,59","14,15"
"low bq, low freq, many artifacts, many samples",UPN2_046,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8042,164,8251,"0,0198763786",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"28,67","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_047,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1836,28,1871,"0,0149652592",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"28,67","15,57"
"low bq, low freq, many artifacts, many samples",UPN2_006,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3686,46,3748,"0,0122732124",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"29,95","14,43"
"low bq, many samples",UPN2_049,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),698,20,722,"0,027700831",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"28,11",14
"low bq, low freq, many artifacts, many samples",UPN2_051,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7527,130,7692,"0,016900676",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"28,48","14,2"
"low bq, low freq, many artifacts, many samples",UPN2_052,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),15213,319,15615,"0,0204290746",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"28,59","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_053,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),20982,417,21530,"0,0193683233",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"28,54","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_009,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),22274,227,22582,"0,010052254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"30,39","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_055,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7098,133,7268,"0,0182993946",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"28,77","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_090,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5220,100,5338,"0,0187336081",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"27,05","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_012,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5735,65,5823,"0,0111626309",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"29,96","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_013,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4713,55,4790,"0,0114822547",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"30,24","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_092,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4408,70,4495,"0,0155728587",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"27,79",15
"low bq, low freq, many artifacts, many samples",UPN2_062,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4421,98,4544,"0,0215669014",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"27,13","14,27"
"low bq, bad alignment, many samples",UPN2_065,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1704,44,1760,"0,025",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"26,84","14,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_066,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),12588,249,12916,"0,0192784144",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"26,84",15
"low bq, low freq, many artifacts, many samples",UPN2_068,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2186,24,2221,"0,0108059433",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"29,39","14,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3595,70,3695,"0,0189445196",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"26,67","14,36"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1604,34,1647,"0,0206435944",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"26,97","14,79"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),11018,201,11280,"0,0178191489",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"26,61","14,58"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_075,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),6738,141,6911,"0,0204022573",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"26,7","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_076,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7126,121,7304,"0,0165662651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"27,05","14,43"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),16670,291,17063,"0,0170544453",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"26,74","14,71"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2935,65,3014,"0,0215660252",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"26,5","18,55"
"low bq, low freq, many artifacts, many samples",UPN2_083,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10198,193,10451,"0,0184671323",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"27,09","14,49"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),18649,328,19088,"0,0171835708",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"26,87","14,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5954,98,6097,"0,0160734788",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"26,83","14,81"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_087,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),18621,337,19071,"0,0176708091",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"26,75","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_095,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),9491,158,9683,"0,016317257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"27,96","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_097,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4325,56,4407,"0,012707057",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"28,78","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_101,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8765,128,8922,"0,0143465591",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"28,27","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_103,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8410,139,8590,"0,0161816065",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"28,32","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_104,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),9649,165,9846,"0,0167580743",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"28,12","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_105,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1865,31,1897,"0,016341592",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"29,68","14,42"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_106,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2778,55,2846,"0,0193253689",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"26,82",14
"low bq, low freq, many artifacts, many samples",UPN2_107,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),14883,227,15182,"0,0149519167",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"27,69","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_108,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10942,183,11166,"0,0163890382",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"28,07","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_110,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10709,132,10880,"0,0121323529",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"28,17","14,74"
"low bq, low freq, many artifacts",UPN2_111,7,148543653,C,A,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg52Ile/c.155G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),11863,170,12092,"0,0140588819",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,28,Damaging,"28,06","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_042,7,148543654,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg52*/c.154A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1740,23,1772,"0,012979684",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,44",19
"low bq, low freq, many artifacts, many samples",UPN2_046,7,148543654,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg52*/c.154A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8092,89,8268,"0,0107643928",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,15","20,37"
"low bq, low freq, many artifacts, many samples",UPN2_066,7,148543654,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg52*/c.154A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),12737,146,12948,"0,0112758727",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,5","16,36"
"low freq, many artifacts, many samples",UPN2_040,7,148543654,T,C,missense_variant(MODERATE|MISSENSE|Aga/Gga|p.Arg52Gly/c.154A>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),11101,113,11252,"0,0100426591",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,02",Neutral,85,Tolerated,30,"28,07"
"low bq, low freq, many artifacts",UPN2_065,7,148543654,T,C,missense_variant(MODERATE|MISSENSE|Aga/Gga|p.Arg52Gly/c.154A>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),1723,22,1762,"0,0124858116",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,02",Neutral,"0,085",Tolerated,"28,43","27,18"
"low bq, low freq, many artifacts",UPN2_080,7,148543654,T,C,missense_variant(MODERATE|MISSENSE|Aga/Gga|p.Arg52Gly/c.154A>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),2964,32,3023,"0,0105855111",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,02",Neutral,"0,085",Tolerated,"28,26","26,16"
"low bq, low freq, many artifacts, many samples",UPN2_062,7,148543655,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu51Asp/c.153A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4500,46,4554,"0,0101010101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,17",Neutral,123,Tolerated,"29,06","15,43"
"low bq, low freq, many artifacts",UPN2_075,7,148543655,T,A,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu51Asp/c.153A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),6845,71,6931,"0,0102438321",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,17",Neutral,123,Tolerated,"28,88","15,37"
"low bq, low freq, many artifacts, many samples",UPN2_020,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8793,94,8924,"0,0105333931",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,43","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_002,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),9685,106,9828,"0,0107855108",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,62","16,27"
"low bq, low freq, many artifacts, many samples",UPN2_004,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1766,20,1797,"0,0111296605",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,42",14
"low bq, low freq, many artifacts, many samples",UPN2_042,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1733,32,1772,"0,0180586907",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,33",14
"low bq, low freq, many artifacts, many samples",UPN2_005,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2286,38,2330,"0,0163090129",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,48","15,97"
"low bq, low freq, many artifacts, many samples",UPN2_045,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7098,145,7289,"0,0198929894",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,39","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_046,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8058,156,8274,"0,0188542422",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,54","14,62"
"low bq, many samples",UPN2_047,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1816,42,1874,"0,022411953",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,51","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_006,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3665,52,3752,"0,0138592751",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,11","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_051,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7493,166,7710,"0,0215304799",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,3","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_052,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),15301,253,15650,"0,0161661342",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,52","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_053,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),21004,409,21565,"0,018965917",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,46","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_009,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),22194,288,22595,"0,0127461828",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,56","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_055,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7098,147,7279,"0,0201950817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,43","14,42"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_090,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5252,69,5351,"0,012894786",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,31","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_012,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5728,72,5829,"0,0123520329",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,98","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_013,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4688,71,4791,"0,0148194531",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,32","14,1"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_091,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7122,127,7281,"0,017442659",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"24,95","14,23"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_092,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4421,64,4506,"0,0142032845",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,03","14,31"
"low bq, bad alignment, many samples",UPN2_062,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4417,111,4555,"0,0243688255",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,04","15,98"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_065,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1708,37,1762,"0,0209988649",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,9","14,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_066,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),12589,261,12950,"0,0201544402",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,01","14,64"
"low bq, many samples",UPN2_067,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1263,30,1300,"0,0230769231",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,36","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_068,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2182,33,2223,"0,0148448043",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,57",14
"low bq, low freq, many artifacts, many samples",UPN2_069,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2759,34,2804,"0,012125535",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,63","14,38"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3607,76,3706,"0,0205072855",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,78","14,53"
"low bq, bad alignment, many samples",UPN2_073,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1597,47,1648,"0,0285194175",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,85","14,55"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),11019,218,11315,"0,0192664605",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,91","14,73"
"low bq, bad alignment, many samples",UPN2_075,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),6726,154,6931,"0,022219016",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,87","14,7"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7123,154,7324,"0,0210267613",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,18","15,2"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),16675,308,17118,"0,0179927562",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,09","14,66"
"low bq, bad alignment, many samples",UPN2_080,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2928,69,3023,"0,0228250083",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,01","14,19"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10195,194,10478,"0,0185149838",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,26","14,79"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),18626,378,19130,"0,01975954",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,04","14,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5952,120,6118,"0,019614253",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,98","14,38"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_087,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),18563,410,19117,"0,0214468797",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,94","14,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_095,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),9522,129,9696,"0,0133044554",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,03","14,26"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_097,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4340,55,4419,"0,0124462548",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,9","14,64"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_099,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),6256,104,6400,"0,01625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"24,84","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_100,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5448,56,5538,"0,0101119538",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,29","14,36"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_101,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8768,117,8935,"0,0130945719",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,5","14,52"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_103,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8470,94,8608,"0,0109200743",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,36","14,98"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_104,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),9695,127,9864,"0,0128751014",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,21","14,47"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_106,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2798,45,2855,"0,0157618214",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"24,75","15,09"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_107,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),14944,192,15213,"0,0126207849",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,82","14,84"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_108,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10953,181,11182,"0,0161867287",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,29","14,11"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_110,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10693,149,10895,"0,0136759982",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,23","14,52"
"low bq, bad alignment, low freq, many artifacts",UPN2_111,7,148543657,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu51*/c.151G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),11924,137,12124,"0,011299901",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,06","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_005,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2286,36,2330,"0,0154506438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"28,71","15,47"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7145,103,7291,"0,0141270059",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"26,6","16,17"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8149,118,8279,"0,0142529291",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"26,67","16,06"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1844,25,1875,"0,0133333333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"26,82","16,04"
"low bq, low freq, many artifacts, many samples",UPN2_006,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3680,41,3754,"0,0109216835",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"28,73","16,12"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7559,130,7720,"0,0168393782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"26,6","16,3"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),15364,228,15655,"0,014564037",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"26,88","16,21"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),21169,310,21568,"0,0143731454",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"26,68","16,91"
"low bq, low freq, many artifacts, many samples",UPN2_007,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),14014,143,14177,"0,0100867602",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"29,86","18,9"
"low bq, low freq, many artifacts, many samples",UPN2_011,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),9159,100,9271,"0,0107863229",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"29,68","20,13"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7158,103,7283,"0,0141425237",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"26,7","17,61"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_090,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5228,114,5354,"0,0212924916",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"25,76","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_012,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5754,63,5831,"0,0108043217",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"28,77","16,76"
"low bq, low freq, many artifacts, many samples",UPN2_013,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4737,48,4793,"0,0100146046",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"28,86","17,04"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_091,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7104,155,7283,"0,0212824386",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"25,49","15,05"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_092,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4428,72,4509,"0,0159680639",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"26,29","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_061,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1406,23,1439,"0,0159833218",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"28,09","21,04"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4421,99,4555,"0,0217343578",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"26,36","15,07"
"low bq, bad alignment, many samples",UPN2_065,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1719,39,1764,"0,0221088435",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"25,92","15,36"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_066,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),12624,278,12954,"0,0214605527",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"26,11","15,93"
"low bq, low freq, many artifacts, many samples",UPN2_067,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1270,24,1300,"0,0184615385",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"27,75","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_068,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2181,32,2223,"0,0143949618",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"28,02","15,25"
"low bq, low freq, many artifacts, many samples",UPN2_069,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2739,55,2805,"0,0196078431",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"28,07","16,11"
"low bq, many samples",UPN2_070,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),858,23,882,"0,0260770975",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"27,73","21,3"
"low bq, bad alignment, many samples",UPN2_071,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3603,96,3707,"0,0258969517",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"26,02","16,48"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1612,32,1648,"0,0194174757",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"26,3","15,78"
"low bq, bad alignment, many samples",UPN2_074,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),11028,261,11326,"0,0230443228",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"26,17","15,53"
"low bq, bad alignment, many samples",UPN2_075,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),6761,156,6937,"0,0224881073",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"25,94","14,96"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7162,143,7329,"0,0195115295",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"26,31","15,99"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),16712,365,17134,"0,021302673",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"26,13","15,64"
"low bq, bad alignment, many samples",UPN2_080,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2921,88,3027,"0,0290716881",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"26,15","18,35"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10242,223,10488,"0,0212623951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"26,32","16,65"
"low bq, bad alignment, many samples",UPN2_084,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),18619,422,19138,"0,022050371",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"26,16","16,36"
"low bq, bad alignment, many samples",UPN2_086,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5933,152,6116,"0,024852845",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"26,2","17,47"
"low bq, bad alignment, many samples",UPN2_087,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),18611,446,19118,"0,0233288001",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"25,91","16,35"
"low bq, low freq, many artifacts, many samples",UPN2_094,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7011,83,7112,"0,0116704162",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"27,37","15,29"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_095,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),9512,163,9701,"0,0168023915",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"26,25","15,04"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_097,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4343,66,4420,"0,0149321267",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"26,99","15,32"
"low bq, bad alignment, many samples",UPN2_099,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),6243,152,6403,"0,0237388724",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"25,34","15,17"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_101,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8770,152,8939,"0,0170041392",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"26,65","14,96"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_103,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8462,141,8612,"0,0163725035",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"26,5","15,07"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_104,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),9675,171,9868,"0,0173287394",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"26,37","14,7"
"low freq, many artifacts, many samples",UPN2_105,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1875,22,1902,"0,0115667718",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,27,"14,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_106,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2789,59,2856,"0,0206582633",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"25,45","15,05"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_107,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),14872,290,15215,"0,019060138",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"26,15","15,13"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_108,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10986,166,11185,"0,0148413053",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"26,41","15,42"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_110,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10714,166,10899,"0,0152307551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"26,51","14,64"
"low bq, bad alignment, low freq, many artifacts",UPN2_111,7,148543658,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu50Phe/c.150G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),11883,210,12126,"0,0173181593",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,478,Tolerated,"26,45","15,4"
"low bq, low freq, many artifacts, many samples",UPN2_006,7,148543663,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile49Phe/c.145A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3691,41,3755,"0,010918775",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,12",Neutral,41,Damaging,"32,21","26,12"
"low bq, low freq, many artifacts, many samples",UPN2_012,7,148543663,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile49Phe/c.145A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5753,60,5827,"0,0102968938",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,12",Neutral,41,Damaging,"32,12","18,85"
"low bq, low freq, many artifacts, many samples",UPN2_074,7,148543664,T,A,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys48Asn/c.144A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),11133,124,11301,"0,0109724803",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,87,Tolerated,"27,96","17,13"
"low bq, low freq, many artifacts",UPN2_075,7,148543664,T,A,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys48Asn/c.144A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),6817,70,6913,"0,0101258498",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,87,Tolerated,"28,25","14,31"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_091,7,148543666,T,A,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys48*/c.142A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7137,86,7243,"0,0118735331",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,73","15,78"
"low bq, low freq, many artifacts, many samples",UPN2_092,7,148543666,T,A,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys48*/c.142A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4444,45,4499,"0,0100022227",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,78",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,7,148543666,T,A,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys48*/c.142A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4431,62,4510,"0,0137472284",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,54","16,24"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_065,7,148543666,T,A,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys48*/c.142A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1687,27,1730,"0,0156069364",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,53",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_066,7,148543666,T,A,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys48*/c.142A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),12643,201,12873,"0,015614076",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,48","15,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,7,148543666,T,A,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys48*/c.142A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3616,68,3689,"0,0184331797",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,27",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,7,148543666,T,A,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys48*/c.142A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1598,36,1640,"0,0219512195",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,42","14,36"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,7,148543666,T,A,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys48*/c.142A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),11093,160,11274,"0,0141919461",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,27","14,55"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_075,7,148543666,T,A,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys48*/c.142A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),6772,90,6892,"0,0130586187",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,24","14,08"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,7,148543666,T,A,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys48*/c.142A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7148,91,7260,"0,0125344353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,53","15,71"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,7,148543666,T,A,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys48*/c.142A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),16678,261,16979,"0,01537193",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,43","15,89"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,7,148543666,T,A,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys48*/c.142A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2951,58,3015,"0,0192371476",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,45","14,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,7,148543666,T,A,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys48*/c.142A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10248,150,10427,"0,0143857294",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,65","15,59"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,7,148543666,T,A,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys48*/c.142A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),18661,279,18980,"0,0146996839",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,5","14,41"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,7,148543666,T,A,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys48*/c.142A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5976,86,6075,"0,0141563786",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,41","15,13"
"low bq, bad alignment, low freq, many artifacts",UPN2_087,7,148543666,T,A,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys48*/c.142A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),18642,308,19014,"0,0161985905",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,38","15,57"
"low bq, low freq, many artifacts, many samples",UPN2_001,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1978,26,2013,"0,0129160457",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"31,35","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_016,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4307,53,4388,"0,0120783956",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"28,67",14
"low bq, low freq, many artifacts, many samples",UPN2_017,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3076,41,3130,"0,0130990415",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"28,99","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_018,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4460,58,4546,"0,012758469",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"28,93","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_020,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4368,65,4475,"0,0145251397",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"27,4","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_021,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5034,78,5152,"0,0151397516",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"27,43","14,09"
"low bq, low freq, many artifacts, many samples",UPN2_002,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4785,55,4876,"0,0112797375",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"28,93","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_022,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4049,66,4143,"0,0159304852",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,28,"14,94"
"low bq, low freq, many artifacts, many samples",UPN2_024,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2808,36,2857,"0,01260063",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"28,57","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_025,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7233,84,7365,"0,0114052953",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"28,93","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_026,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8792,144,9003,"0,0159946684",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"27,66","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_027,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8698,105,8860,"0,0118510158",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"29,01","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_089,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4111,45,4191,"0,0107372942",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"29,76","15,58"
"low bq, low freq, many artifacts, many samples",UPN2_028,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),6373,97,6504,"0,0149138991",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"29,03","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_030,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1830,28,1865,"0,0150134048",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"31,5","16,07"
"low bq, bad alignment, many samples",UPN2_045,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3417,78,3541,"0,0220276758",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"26,65","14,35"
"low bq, bad alignment, many samples",UPN2_046,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3899,104,4052,"0,0256663376",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"26,45","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_033,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4898,58,4984,"0,0116372392",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"28,81","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_034,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2029,22,2067,"0,0106434446",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"29,48",14
"low bq, bad alignment, many samples",UPN2_047,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),888,24,920,"0,0260869565",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"26,19","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_006,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1823,29,1862,"0,0155746509",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"28,09","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_037,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8119,104,8280,"0,0125603865",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"28,93","14,67"
"low bq, bad alignment, many samples",UPN2_051,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3618,85,3747,"0,0226848145",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"26,24","14,47"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7375,159,7639,"0,0208142427",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"26,47","14,13"
"low bq, low freq, many artifacts, many samples",UPN2_038,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10367,164,10601,"0,0154702387",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"28,87","14,31"
"low bq, bad alignment, many samples",UPN2_053,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10135,250,10528,"0,0237462006",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"26,52","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_007,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7000,87,7111,"0,0122345662",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"30,96","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_008,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10255,136,10426,"0,0130443123",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"31,18","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_009,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10931,191,11214,"0,0170322811",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"29,18","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_010,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5617,69,5705,"0,0120946538",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"31,29","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_011,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4518,70,4614,"0,015171218",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"31,21","16,69"
"low bq, bad alignment, many samples",UPN2_055,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3399,94,3542,"0,0265386787",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"26,69","14,88"
"low bq, many samples",UPN2_090,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2525,59,2618,"0,0225362872",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"27,36","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_012,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2814,47,2887,"0,0162798753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"28,64","14,15"
"low bq, low freq, many artifacts, many samples",UPN2_040,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5557,77,5664,"0,0135946328",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"28,72","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_013,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2317,39,2372,"0,0164418212",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"28,87","14,33"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_091,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3429,60,3523,"0,0170309395",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"26,61","16,02"
"low bq, low freq, many artifacts, many samples",UPN2_092,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2139,30,2188,"0,0137111517",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"28,01","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_093,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2669,48,2734,"0,0175566935",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"30,12","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_062,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2172,45,2241,"0,0200803213",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"27,02","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_066,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),6178,114,6373,"0,0178879649",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"27,03","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_069,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1372,20,1406,"0,0142247511",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"29,81","14,35"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1749,30,1804,"0,0166297118",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"26,31","14,97"
"low bq, many samples",UPN2_073,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),790,23,823,"0,0279465371",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"27,31","14,57"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5355,120,5551,"0,0216177265",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"26,79","15,1"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_075,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3283,64,3396,"0,0188457008",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"26,98","14,81"
"low bq, many samples",UPN2_076,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3488,88,3626,"0,0242691671",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"27,4","14,66"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8185,179,8470,"0,021133412",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"26,9","15,12"
"low bq, bad alignment, many samples",UPN2_080,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1436,34,1494,"0,0227576975",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"26,76",15
"low bq, low freq, many artifacts, many samples",UPN2_083,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4984,99,5144,"0,0192457232",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"27,03","15,96"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),9050,206,9378,"0,0219663041",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"26,89","14,84"
"low bq, bad alignment, many samples",UPN2_086,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2902,67,3006,"0,0222887558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"26,83","14,87"
"low bq, bad alignment, many samples",UPN2_087,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),9026,220,9381,"0,0234516576",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"26,85","15,37"
"low bq, low freq, many artifacts, many samples",UPN2_094,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3474,47,3548,"0,0132468997",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"29,3","14,15"
"low bq, low freq, many artifacts, many samples",UPN2_095,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4640,85,4752,"0,0178872054",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"27,86","15,58"
"low bq, low freq, many artifacts, many samples",UPN2_096,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3270,43,3326,"0,0129284426",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"29,93","15,3"
"low bq, low freq, many artifacts, many samples",UPN2_097,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2125,24,2177,"0,0110243454",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"28,66","17,42"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_099,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3018,54,3106,"0,0173857051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"26,75","15,74"
"low bq, low freq, many artifacts, many samples",UPN2_100,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2719,34,2765,"0,0122965642",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"29,91","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_101,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4265,66,4371,"0,0150995196",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"28,17","16,02"
"low bq, low freq, many artifacts, many samples",UPN2_102,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4004,49,4074,"0,0120274914",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"30,01","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_103,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4095,76,4214,"0,018035121",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"28,2","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_104,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4719,69,4824,"0,0143034826",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"27,92","15,57"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_106,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1355,28,1395,"0,0200716846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"26,89","15,93"
"low bq, low freq, many artifacts, many samples",UPN2_107,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7291,116,7468,"0,0155329405",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"28,13","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_108,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5378,94,5514,"0,0170475154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"28,16","15,77"
"low bq, low freq, many artifacts, many samples",UPN2_109,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5182,62,5274,"0,0117557831",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"30,42","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_110,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5235,77,5352,"0,014387145",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"28,43","15,29"
"low bq, low freq, many artifacts",UPN2_111,7,148543667,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln47His/c.141G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5825,94,5957,"0,0157797549",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,29,Damaging,"28,13","15,98"
"low bq, many samples",UPN2_001,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1920,45,1968,"0,0228658537",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"31,5","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_014,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3930,80,4016,"0,0199203187",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"30,45","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_015,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),6117,109,6236,"0,0174791533",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"30,7","14,45"
"low bq, many samples",UPN2_016,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4167,102,4278,"0,0238429173",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"28,96",14
"low bq, many samples",UPN2_017,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2987,79,3072,"0,0257161458",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"28,96","14,39"
"low bq, many samples",UPN2_018,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4325,109,4443,"0,0245329732",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"28,92","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_019,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4088,76,4168,"0,0182341651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"30,65",14
"low bq, many samples",UPN2_020,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4240,115,4361,"0,0263700986",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"27,61","14,45"
"low bq, many samples",UPN2_021,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4890,128,5028,"0,0254574383",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"27,93",14
"low bq, many samples",UPN2_002,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4618,178,4805,"0,0370447451",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"29,48","14,75"
"low bq, many samples",UPN2_022,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3914,131,4053,"0,032321737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"27,97","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_023,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4471,84,4560,"0,0184210526",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"30,46",14
"low bq, many samples",UPN2_024,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2732,62,2800,"0,0221428571",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"28,82","14,29"
"low bq, many samples",UPN2_025,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),6999,213,7229,"0,0294646562",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"28,94","14,27"
"low bq, many samples",UPN2_026,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),8466,311,8793,"0,0353690436",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"27,65","14,32"
"low bq, many samples",UPN2_004,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),844,31,875,"0,0354285714",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"28,91",15
"low bq, many samples",UPN2_027,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),8392,271,8680,"0,0312211982",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"28,95","14,29"
"low bq, many samples",UPN2_089,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3951,172,4134,"0,0416061925",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"28,35","14,12"
"low bq, many samples",UPN2_042,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),799,47,847,"0,0554899646",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"27,16",14
"low bq, many samples",UPN2_028,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),6129,187,6333,"0,0295278699",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"28,74","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_029,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4688,85,4788,"0,0177527151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"30,71","14,26"
"low bq, many samples",UPN2_005,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1083,50,1140,"0,0438596491",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"28,84","14,26"
"low bq, bad alignment, many samples",UPN2_045,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3263,188,3465,"0,0542568543",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"26,46","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_032,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1685,24,1711,"0,0140268849",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"30,98",14
"low bq, bad alignment, many samples",UPN2_046,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3754,194,3961,"0,0489775309",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"26,58","14,31"
"low bq, many samples",UPN2_033,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4765,120,4888,"0,0245499182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"29,01","14,15"
"low bq, many samples",UPN2_034,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1962,52,2019,"0,0257553244",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"29,04","14,5"
"low bq, many samples",UPN2_047,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),855,45,902,"0,0498891353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"27,04","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_036,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5088,76,5181,"0,0146689828",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"30,6","14,29"
"low bq, many samples",UPN2_006,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1764,65,1832,"0,0354803493",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"28,53","14,68"
"low bq, many samples",UPN2_037,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7851,231,8098,"0,0285255619",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"28,91","14,29"
"low bq, bad alignment, many samples",UPN2_051,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3435,214,3660,"0,0584699454",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"26,55","14,33"
"low bq, bad alignment, many samples",UPN2_052,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7008,438,7473,"0,0586109996",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"26,43","14,42"
"low bq, many samples",UPN2_038,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),10018,286,10328,"0,0276917119",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"28,64","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_039,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4283,54,4347,"0,0124223602",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"30,31","14,33"
"low bq, bad alignment, many samples",UPN2_053,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),9631,615,10284,"0,0598016336",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"26,43","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_007,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),6809,149,6968,"0,0213834673",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"31,44","14,13"
"low bq, many samples",UPN2_008,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),9988,237,10239,"0,0231467917",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"31,41","14,57"
"low bq, many samples",UPN2_009,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),10548,436,11017,"0,039575202",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"29,66","14,39"
"low bq, many samples",UPN2_010,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5424,131,5560,"0,0235611511",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"31,48","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_011,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4420,93,4558,"0,0204036858",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"31,37","14,28"
"low bq, bad alignment, many samples",UPN2_055,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3238,203,3460,"0,0586705202",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"26,61","14,38"
"low bq, bad alignment, many samples",UPN2_090,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2405,170,2582,"0,0658404338",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"25,79","14,52"
"low bq, many samples",UPN2_012,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2715,108,2828,"0,0381895332",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"28,98","14,56"
"low bq, many samples",UPN2_040,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5370,145,5524,"0,0262490949",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"28,59","14,58"
"low bq, many samples",UPN2_013,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2231,95,2330,"0,0407725322",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"29,29","14,55"
"low bq, bad alignment, many samples",UPN2_091,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3241,233,3485,"0,0668579627",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"25,27","14,42"
"low bq, bad alignment, many samples",UPN2_092,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2033,134,2173,"0,0616658997",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"26,2","14,92"
"low bq, many samples",UPN2_093,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2561,104,2670,"0,0389513109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"28,85","15,4"
"low bq, many samples",UPN2_061,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),671,30,703,"0,0426742532",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"29,25",14
"low bq, bad alignment, many samples",UPN2_062,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2023,158,2191,"0,0721131903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"26,23","14,94"
"low bq, bad alignment, many samples",UPN2_065,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),775,67,847,"0,0791027155",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"26,71",14
"low bq, bad alignment, many samples",UPN2_066,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5752,442,6232,"0,0709242619",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"26,41","14,5"
"low bq, many samples",UPN2_068,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1031,44,1079,"0,0407784986",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"29,11","14,91"
"low bq, many samples",UPN2_069,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1320,46,1371,"0,0335521517",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"29,16","14,7"
"low bq, bad alignment, many samples",UPN2_071,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1633,132,1773,"0,0744500846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"25,94","14,48"
"low bq, bad alignment, many samples",UPN2_073,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),726,66,793,"0,0832282472",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"26,77","14,61"
"low bq, bad alignment, many samples",UPN2_074,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4944,466,5435,"0,0857405704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"26,04","14,8"
"low bq, bad alignment, many samples",UPN2_075,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3021,288,3327,"0,0865644725",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"26,15","14,71"
"low bq, bad alignment, many samples",UPN2_076,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3241,270,3530,"0,0764872521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"26,34","14,76"
"low bq, bad alignment, many samples",UPN2_077,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7551,664,8247,"0,0805141263",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"26,19","14,96"
"low bq, bad alignment, many samples",UPN2_080,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1347,97,1452,"0,0668044077",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"26,33","14,62"
"low bq, bad alignment, many samples",UPN2_083,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4620,380,5038,"0,0754267566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"26,47","14,74"
"low bq, bad alignment, many samples",UPN2_084,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),8510,636,9196,"0,0691605046",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"26,29","14,66"
"low bq, bad alignment, many samples",UPN2_086,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2710,205,2933,"0,0698943062",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"26,46","14,52"
"low bq, bad alignment, many samples",UPN2_087,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),8464,662,9195,"0,0719956498",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"26,4","14,61"
"low bq, many samples",UPN2_094,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3335,138,3485,"0,0395982783",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"27,96","14,62"
"low bq, bad alignment, many samples",UPN2_095,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4404,269,4692,"0,0573316283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"26,64","14,71"
"low bq, many samples",UPN2_096,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3133,136,3274,"0,0415394013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"28,59","14,4"
"low bq, many samples",UPN2_097,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2036,108,2147,"0,050302748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"27,5","14,84"
"low bq, many samples",UPN2_100,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2600,115,2718,"0,0423105224",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"28,65","14,56"
"low bq, bad alignment, many samples",UPN2_101,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4049,254,4316,"0,0588507878",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"26,62","14,52"
"low bq, many samples",UPN2_102,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3838,159,4004,"0,0397102897",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"28,77","14,28"
"low bq, bad alignment, many samples",UPN2_103,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3873,265,4145,"0,0639324487",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"26,86","14,63"
"low bq, bad alignment, many samples",UPN2_104,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4421,318,4753,"0,0669051126",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"26,76","14,81"
"low bq, many samples",UPN2_105,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),891,41,935,"0,0438502674",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"28,21","14,44"
"low bq, bad alignment, many samples",UPN2_106,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1245,123,1371,"0,0897155361",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"25,32","14,93"
"low bq, bad alignment, many samples",UPN2_107,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),6803,543,7370,"0,0736770692",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"26,38","15,1"
"low bq, bad alignment, many samples",UPN2_108,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5040,372,5419,"0,0686473519",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"26,71","14,94"
"low bq, many samples",UPN2_109,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4978,217,5204,"0,0416986933",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"29,04","14,71"
"low bq, bad alignment, many samples",UPN2_110,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4942,331,5290,"0,0625708885",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"26,71","15,33"
"low bq, bad alignment",UPN2_111,7,148543669,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln47Lys/c.139C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5407,439,5868,"0,0748125426",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,645,Tolerated,"26,54","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_001,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1938,24,1967,"0,0122013218",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"31,13",14
"low bq, low freq, many artifacts, many samples",UPN2_016,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4209,56,4279,"0,0130871699",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"28,75",14
"low bq, low freq, many artifacts, many samples",UPN2_017,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3020,40,3072,"0,0130208333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"28,98",14
"low bq, low freq, many artifacts, many samples",UPN2_018,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4368,59,4441,"0,0132852961",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"28,97",14
"low bq, low freq, many artifacts, many samples",UPN2_020,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4273,72,4358,"0,0165213401",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"27,58","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_021,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4923,85,5025,"0,0169154229",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"27,85","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_002,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4709,76,4802,"0,0158267389",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"29,37","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_022,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3975,60,4049,"0,0148184737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"28,52",14
"low bq, low freq, many artifacts, many samples",UPN2_024,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2746,45,2800,"0,0160714286",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"28,87","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_025,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7114,88,7229,"0,0121731913",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"29,12","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_026,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8599,159,8793,"0,0180825657",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"28,27","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_027,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8518,126,8680,"0,014516129",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"29,11","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_089,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4058,62,4134,"0,014997581",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"27,79","14,35"
"low bq, bad alignment, many samples",UPN2_042,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),821,21,847,"0,0247933884",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"26,33","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_028,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),6248,70,6331,"0,0110567051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"29,25","14,19"
"low bq, bad alignment, many samples",UPN2_045,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3324,125,3468,"0,0360438293",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"26,51","14,34"
"low bq, bad alignment, many samples",UPN2_046,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3795,146,3963,"0,0368407772",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"26,54","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_033,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4801,67,4888,"0,0137070376",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"28,92",14
"low bq, low freq, many artifacts, many samples",UPN2_034,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1974,37,2019,"0,0183259039",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"29,55","14,59"
"low bq, bad alignment, many samples",UPN2_047,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),872,29,904,"0,032079646",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"26,46","15,48"
"low bq, low freq, many artifacts, many samples",UPN2_006,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1786,36,1832,"0,019650655",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"28,97",14
"low bq, low freq, many artifacts, many samples",UPN2_037,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7963,99,8097,"0,0122267506",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"29,16","14,46"
"low bq, bad alignment, many samples",UPN2_051,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3523,119,3661,"0,0325047801",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"26,47","14,35"
"low bq, bad alignment, many samples",UPN2_052,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7188,238,7472,"0,0318522484",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"26,66","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_038,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10154,138,10325,"0,0133656174",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"28,95","14,33"
"low bq, bad alignment, many samples",UPN2_053,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),9880,346,10287,"0,0336346846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"26,39","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_007,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),6852,81,6967,"0,011626238",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"30,82","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_008,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10066,119,10238,"0,0116233639",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"31,04","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_009,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10756,215,11018,"0,0195135233",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"29,51","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_010,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5471,71,5558,"0,0127743793",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"31,12","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_011,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4483,64,4558,"0,0140412462",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"30,79","14,31"
"low bq, bad alignment, many samples",UPN2_055,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3346,95,3461,"0,0274487142",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"26,44","14,61"
"low bq, bad alignment, many samples",UPN2_090,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2501,66,2582,"0,0255615802",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"25,59","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_012,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2769,45,2829,"0,0159066808",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"28,54",14
"low bq, low freq, many artifacts, many samples",UPN2_040,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5451,62,5524,"0,0112237509",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"28,78","14,11"
"low bq, low freq, many artifacts, many samples",UPN2_013,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2276,42,2330,"0,0180257511",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"29,16",14
"low bq, bad alignment, many samples",UPN2_092,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2108,48,2173,"0,0220892775",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"26,27",14
"low bq, low freq, many artifacts, many samples",UPN2_093,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2620,40,2670,"0,0149812734",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"28,4",14
"low bq, bad alignment, many samples",UPN2_062,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2109,63,2189,"0,028780265",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"26,85","14,56"
"low bq, bad alignment, many samples",UPN2_065,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),821,24,848,"0,0283018868",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"26,79","14,54"
"low bq, bad alignment, many samples",UPN2_066,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5984,216,6233,"0,0346542596",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"26,81","14,91"
"low bq, many samples",UPN2_068,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1047,28,1079,"0,0259499537",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"28,95","14,25"
"low bq, many samples",UPN2_069,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1326,33,1371,"0,0240700219",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"28,85",14
"low bq, bad alignment, many samples",UPN2_071,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1700,58,1773,"0,032712916",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"26,43","14,55"
"low bq, bad alignment, many samples",UPN2_073,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),767,24,793,"0,0302648172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"26,86","14,54"
"low bq, bad alignment, many samples",UPN2_074,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5258,147,5434,"0,0270518955",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"26,55","14,22"
"low bq, bad alignment, many samples",UPN2_075,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3207,105,3329,"0,0315410033",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"26,51","14,7"
"low bq, bad alignment, many samples",UPN2_076,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3388,104,3525,"0,0295035461",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"26,69","14,88"
"low bq, bad alignment, many samples",UPN2_080,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1399,44,1452,"0,0303030303",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"26,65","14,41"
"low bq, bad alignment, many samples",UPN2_083,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4852,154,5038,"0,0305676856",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"26,98","14,6"
"low bq, bad alignment, many samples",UPN2_084,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8858,275,9194,"0,0299108114",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"26,58","14,54"
"low bq, bad alignment, many samples",UPN2_086,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2829,87,2937,"0,0296220633",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"26,63","14,23"
"low bq, bad alignment, many samples",UPN2_087,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8819,303,9196,"0,0329491083",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"26,62","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_094,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3420,58,3486,"0,0166379805",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"27,47","14,69"
"low bq, bad alignment, many samples",UPN2_095,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4545,123,4693,"0,0262092478",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"26,38",14
"low bq, low freq, many artifacts, many samples",UPN2_096,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3220,47,3274,"0,0143555284",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"28,07",14
"low bq, bad alignment, many samples",UPN2_097,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2084,51,2146,"0,0237651445",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"26,89","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_100,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2661,42,2719,"0,0154468555",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"28,06","14,31"
"low bq, bad alignment, many samples",UPN2_101,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4208,96,4316,"0,0222428174",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"26,86","14,07"
"low bq, low freq, many artifacts, many samples",UPN2_102,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3933,51,4003,"0,0127404447",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"28,08","14,14"
"low bq, bad alignment, many samples",UPN2_103,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4026,98,4145,"0,0236429433",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"26,72","14,79"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_104,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4638,102,4751,"0,0214691644",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"26,43","14,47"
"low bq, bad alignment, many samples",UPN2_106,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1338,32,1371,"0,0233406273",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"25,08","14,69"
"low bq, bad alignment, many samples",UPN2_107,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7166,181,7372,"0,0245523603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"26,34","14,22"
"low bq, bad alignment, many samples",UPN2_108,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5256,122,5419,"0,0225133789",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"26,44","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_109,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5107,75,5204,"0,0144119908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"28,36","14,09"
"low bq, bad alignment, many samples",UPN2_110,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5156,121,5293,"0,0228603816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"26,54","14,55"
"low bq, bad alignment, low freq, many artifacts",UPN2_111,7,148543671,C,A,missense_variant(MODERATE|MISSENSE|cGt/cTt|p.Arg46Leu/c.137G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5698,127,5867,"0,0216464974",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,74",Tolerated,"26,53","14,06"
"low bq, low freq, many artifacts, many samples",UPN2_016,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4209,47,4279,"0,0109838747",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"29,31","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_017,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3021,37,3073,"0,0120403514",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"29,11","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_018,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4372,60,4441,"0,0135104706",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"29,31","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_021,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4926,77,5028,"0,0153142403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"27,85","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_002,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4690,87,4802,"0,0181174511",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"29,08","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_022,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3979,55,4049,"0,0135836009",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"28,26","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_024,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2761,30,2799,"0,0107181136",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"28,96",14
"low bq, low freq, many artifacts, many samples",UPN2_025,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7109,90,7229,"0,0124498548",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"29,32","14,2"
"low bq, many samples",UPN2_004,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),846,24,876,"0,0273972603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"28,98",14
"low bq, low freq, many artifacts, many samples",UPN2_027,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),8532,102,8680,"0,0117511521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"29,17",14
"low bq, low freq, many artifacts, many samples",UPN2_089,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4071,53,4134,"0,0128205128",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"30,01","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_029,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4725,50,4788,"0,0104427736",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"31,21",14
"low bq, many samples",UPN2_005,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1098,27,1140,"0,0236842105",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"28,96",14
"low bq, low freq, many artifacts, many samples",UPN2_033,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4809,56,4888,"0,0114566285",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"29,19",14
"low bq, low freq, many artifacts, many samples",UPN2_034,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1983,26,2019,"0,0128776622",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"29,55",14
"low bq, many samples",UPN2_006,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1771,47,1831,"0,0256690333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"28,32","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_037,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7947,110,8098,"0,0135836009",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"29,15","15,05"
"low bq, bad alignment, many samples",UPN2_052,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7202,182,7475,"0,0243478261",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"26,53","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_038,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),10127,129,10324,"0,0124951569",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"28,78","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_007,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),6868,80,6967,"0,0114827042",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"31,48","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_008,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),10086,119,10239,"0,0116222287",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"31,49","14,06"
"low bq, low freq, many artifacts, many samples",UPN2_009,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),10717,236,11017,"0,0214214396",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"29,5","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_010,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5475,63,5558,"0,0113350126",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"31,53",14
"low bq, low freq, many artifacts, many samples",UPN2_011,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4493,52,4558,"0,0114085125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"31,35","14,25"
"low bq, many samples",UPN2_090,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2491,73,2581,"0,028283611",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"27,23",14
"low bq, many samples",UPN2_012,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2738,75,2829,"0,0265111347",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"28,79","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_040,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5420,72,5524,"0,0130340333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"28,89",14
"low bq, bad alignment, many samples",UPN2_091,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3340,117,3484,"0,0335820896",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"26,77","14,28"
"low bq, many samples",UPN2_092,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2095,60,2173,"0,0276115969",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"28,01","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_093,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2607,52,2670,"0,0194756554",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"30,37","21,13"
"low bq, many samples",UPN2_062,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg46Gly/c.136C>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),2092,66,2189,"0,0301507538",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"27,03","14,39"
"low bq, many samples",UPN2_065,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),812,24,848,"0,0283018868",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"27,42","15,46"
"low bq, many samples",UPN2_066,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg46Gly/c.136C>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),5946,178,6233,"0,0285576769",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"27,16","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_069,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1341,23,1371,"0,0167760759",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"30,44",14
"low bq, bad alignment, many samples",UPN2_071,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg46Gly/c.136C>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),1683,60,1774,"0,0338218715",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"26,67","14,55"
"low bq, many samples",UPN2_073,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),758,24,793,"0,0302648172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"27,22",14
"low bq, bad alignment, many samples",UPN2_074,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg46Gly/c.136C>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),5167,183,5441,"0,0336335232",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"26,81","14,39"
"low bq, many samples",UPN2_076,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg46Gly/c.136C>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),3374,90,3526,"0,0255246739",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"27,19","14,39"
"low bq, bad alignment, many samples",UPN2_077,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg46Gly/c.136C>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),7863,244,8251,"0,0295721731",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"26,89","14,13"
"low bq, bad alignment, many samples",UPN2_080,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg46Gly/c.136C>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),1396,33,1452,"0,0227272727",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"26,64",14
"low bq, many samples",UPN2_083,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg46Gly/c.136C>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),4786,153,5039,"0,0303631673",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"27,31","14,26"
"low bq, many samples",UPN2_084,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg46Gly/c.136C>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),8777,266,9195,"0,0289287656",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"27,05","14,55"
"low bq, bad alignment, many samples",UPN2_086,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg46Gly/c.136C>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),2774,114,2939,"0,0387887036",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"26,89","14,39"
"low bq, many samples",UPN2_087,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg46Gly/c.136C>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),8747,295,9201,"0,0320617324",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"27,05","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_094,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3413,51,3486,"0,0146299484",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"29,55","15,08"
"low bq, many samples",UPN2_095,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4523,137,4693,"0,0291924142",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"28,12","14,09"
"low bq, low freq, many artifacts, many samples",UPN2_097,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2094,37,2146,"0,0172413793",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"28,7",14
"low bq, bad alignment, many samples",UPN2_099,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2948,104,3072,"0,0338541667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"26,97","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_100,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2663,45,2719,"0,0165502023",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"30,12","15,18"
"low bq, many samples",UPN2_101,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4196,95,4316,"0,0220111214",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"28,43","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_102,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3931,54,4003,"0,0134898826",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"30,14","14,54"
"low bq, many samples",UPN2_103,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4019,105,4147,"0,0253195081",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"28,31","14,33"
"low bq, many samples",UPN2_104,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4620,110,4751,"0,0231530204",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"28,16",14
"low bq, bad alignment, many samples",UPN2_106,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1319,40,1371,"0,0291757841",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"26,96","14,18"
"low bq, many samples",UPN2_107,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7131,192,7373,"0,0260409603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"28,1","14,27"
"low bq, many samples",UPN2_108,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5248,139,5421,"0,0256410256",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"28,19","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_109,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5103,84,5204,"0,0161414297",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"30,29","16,2"
"low bq, many samples",UPN2_110,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5138,123,5293,"0,0232382392",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"28,28","14,21"
low bq,UPN2_111,7,148543672,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg46Ser/c.136C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5692,134,5868,"0,0228357192",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,283,Tolerated,"28,16","14,15"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,7,148543673,A,C,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn45Lys/c.135T>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),2092,29,2190,"0,0132420091",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"26,96",14
"low bq, low freq, many artifacts, many samples",UPN2_066,7,148543673,A,C,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn45Lys/c.135T>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),5942,73,6236,"0,0117062219",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"27,28","14,3"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,7,148543673,A,C,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn45Lys/c.135T>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),5182,61,5443,"0,0112070549",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"26,89",14
"low bq, low freq, many artifacts, many samples",UPN2_076,7,148543673,A,C,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn45Lys/c.135T>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),3355,47,3528,"0,0133219955",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"27,42","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_077,7,148543673,A,C,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn45Lys/c.135T>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),7853,111,8253,"0,0134496547",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"27,05","14,06"
"low bq, low freq, many artifacts, many samples",UPN2_080,7,148543673,A,C,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn45Lys/c.135T>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),1390,22,1452,"0,0151515152",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"27,17",14
"low bq, low freq, many artifacts, many samples",UPN2_083,7,148543673,A,C,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn45Lys/c.135T>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),4812,68,5040,"0,0134920635",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"27,57","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_084,7,148543673,A,C,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn45Lys/c.135T>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),8714,130,9195,"0,0141381185",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"27,12","14,41"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,7,148543673,A,C,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn45Lys/c.135T>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),2799,40,2941,"0,013600816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"26,68","14,32"
"low bq, low freq, many artifacts",UPN2_087,7,148543673,A,C,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn45Lys/c.135T>G|751|EZH2|protein_coding|CODING|ENST00000320356|3|C),8778,97,9202,"0,0105411867",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"27,35","14,13"
"low bq, many samples",UPN2_014,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3899,98,4017,"0,0243963157",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"29,99","15,57"
"low bq, many samples",UPN2_015,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),6065,140,6234,"0,0224574912",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"29,88","15,07"
"low bq, many samples",UPN2_016,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4092,162,4279,"0,0378593129",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"28,02","15,09"
"low bq, many samples",UPN2_017,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2956,94,3073,"0,030589001",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"27,89","15,02"
"low bq, many samples",UPN2_018,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4273,138,4441,"0,0310740824",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"28,03","14,92"
"low bq, many samples",UPN2_019,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4058,94,4168,"0,0225527831",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"30,1","15,6"
"low bq, bad alignment, many samples",UPN2_021,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4824,167,5028,"0,0332140016",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"26,47","15,26"
"low bq, many samples",UPN2_002,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4585,183,4802,"0,0381091212",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"28,16","14,75"
"low bq, bad alignment, many samples",UPN2_022,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3860,166,4049,"0,0409977772",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"26,85","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_023,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4447,92,4561,"0,0201710151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"29,88","15,29"
"low bq, many samples",UPN2_024,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2686,99,2799,"0,0353697749",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"27,82","15,33"
"low bq, many samples",UPN2_025,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),6948,251,7230,"0,0347164592",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"28,13","14,64"
"low bq, many samples",UPN2_004,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),835,36,876,"0,0410958904",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"27,84","14,5"
"low bq, many samples",UPN2_027,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),8341,283,8680,"0,0326036866",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"28,18","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_089,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4049,73,4135,"0,0176541717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"31,53","14,9"
"low bq, bad alignment, many samples",UPN2_042,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),811,32,848,"0,0377358491",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"26,97","15,09"
"low bq, many samples",UPN2_028,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),6089,200,6332,"0,031585597",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"27,77","14,86"
"low bq, many samples",UPN2_029,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4645,121,4788,"0,0252715121",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"30,15","15,49"
"low bq, low freq, many artifacts, many samples",UPN2_030,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1772,38,1815,"0,0209366391",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"30,17","15,16"
"low bq, many samples",UPN2_005,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1081,55,1140,"0,048245614",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"28,22","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_032,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1663,37,1711,"0,0216247808",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"30,32","16,24"
"low bq, many samples",UPN2_033,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4683,164,4888,"0,0335515548",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"27,86","15,92"
"low bq, many samples",UPN2_034,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1947,60,2019,"0,029717682",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"28,26","14,8"
"low bq, bad alignment, many samples",UPN2_047,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),848,43,904,"0,0475663717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"26,33","14,42"
"low bq, many samples",UPN2_036,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5015,146,5180,"0,0281853282",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"30,1","14,9"
"low bq, many samples",UPN2_006,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1730,88,1832,"0,0480349345",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"27,86","14,7"
"low bq, many samples",UPN2_037,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7793,262,8100,"0,032345679",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"27,89","15,16"
"low bq, bad alignment, many samples",UPN2_052,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7072,333,7476,"0,0445425361",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"26,21","14,97"
"low bq, many samples",UPN2_038,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),9877,384,10324,"0,0371948857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"27,79","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_039,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4239,92,4347,"0,0211640212",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"30,02","15,38"
"low bq, many samples",UPN2_007,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),6735,214,6967,"0,0307162337",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"30,51","14,83"
"low bq, many samples",UPN2_008,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),9878,309,10239,"0,0301787284",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"30,58","15,14"
"low bq, many samples",UPN2_009,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),10520,446,11019,"0,0404755422",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"28,51","14,93"
"low bq, many samples",UPN2_010,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5379,156,5558,"0,0280676502",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"30,66","15,55"
"low bq, many samples",UPN2_011,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4410,136,4558,"0,0298376481",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"30,57","15,47"
"low bq, many samples",UPN2_090,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2509,58,2582,"0,0224632068",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"28,84",14
"low bq, many samples",UPN2_012,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2687,122,2830,"0,0431095406",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"27,42","14,75"
"low bq, many samples",UPN2_040,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5332,163,5524,"0,0295076032",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"27,9","14,73"
"low bq, many samples",UPN2_091,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3373,91,3484,"0,026119403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"28,11","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_092,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2133,31,2173,"0,0142659917",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"29,07","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_093,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2631,33,2671,"0,0123549232",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"31,83",14
"low bq, bad alignment, many samples",UPN2_065,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),810,26,848,"0,0306603774",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"26,92","14,5"
"low bq, many samples",UPN2_068,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1043,28,1079,"0,0259499537",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,30,14
"low bq, low freq, many artifacts, many samples",UPN2_069,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1334,26,1372,"0,0189504373",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"30,54","15,54"
"low bq, bad alignment, many samples",UPN2_071,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1685,69,1775,"0,0388732394",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"26,72","14,64"
"low bq, many samples",UPN2_073,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),758,21,793,"0,026481715",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"27,57",14
"low bq, low freq, many artifacts, many samples",UPN2_094,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3414,58,3486,"0,0166379805",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"30,95",14
"low bq, low freq, many artifacts, many samples",UPN2_095,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4581,86,4693,"0,0183251651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"29,38","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_096,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3215,43,3274,"0,0131337813",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"31,7","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_097,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2108,29,2146,"0,0135135135",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"30,09",14
"low bq, many samples",UPN2_099,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2974,71,3073,"0,0231044582",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"28,01","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_100,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2673,37,2720,"0,0136029412",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"31,67","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_101,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4207,83,4316,"0,0192307692",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"29,6","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_102,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3935,53,4004,"0,0132367632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"31,56","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_103,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4051,80,4148,"0,0192864031",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"29,49","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_104,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4649,79,4752,"0,0166245791",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"29,46","15,01"
"low bq, many samples",UPN2_106,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1330,36,1371,"0,0262582057",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"28,92","16,94"
"low bq, low freq, many artifacts, many samples",UPN2_107,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7177,148,7374,"0,020070518",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"29,26","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_108,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5287,106,5421,"0,0195535879",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"29,35","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_109,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5091,82,5204,"0,0157571099",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"31,75","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_110,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5172,92,5293,"0,0173814472",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"29,69",14
"low bq, low freq, many artifacts",UPN2_111,7,148543673,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn45Lys/c.135T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5719,114,5868,"0,0194274029",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,73",Deleterious,0,Damaging,"29,34","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_046,7,148543674,T,A,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn45Ile/c.134A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3895,58,3966,"0,0146243066",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,09",Deleterious,0,Damaging,"28,04","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_051,7,148543674,T,A,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn45Ile/c.134A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3608,40,3665,"0,0109140518",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,09",Deleterious,0,Damaging,"28,5","15,77"
"low bq, low freq, many artifacts, many samples",UPN2_052,7,148543674,T,A,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn45Ile/c.134A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7346,90,7478,"0,0120353036",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,09",Deleterious,0,Damaging,"27,97","15,72"
"low bq, low freq, many artifacts, many samples",UPN2_053,7,148543674,T,A,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn45Ile/c.134A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10134,129,10296,"0,0125291375",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,09",Deleterious,0,Damaging,"28,03","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_055,7,148543674,T,A,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn45Ile/c.134A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3404,49,3463,"0,0141495813",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,09",Deleterious,0,Damaging,"28,34","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_076,7,148543674,T,A,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn45Ile/c.134A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3482,43,3533,"0,0121709595",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,09",Deleterious,0,Damaging,"28,32","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_084,7,148543674,T,A,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn45Ile/c.134A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),9069,96,9202,"0,0104325147",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,09",Deleterious,0,Damaging,"28,27","14,88"
"low bq, low freq, many artifacts",UPN2_086,7,148543674,T,A,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn45Ile/c.134A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2899,30,2943,"0,0101936799",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,09",Deleterious,0,Damaging,"28,07","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_001,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1925,42,1969,"0,0213306247",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"29,51",14
"low bq, low freq, many artifacts, many samples",UPN2_014,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3949,56,4018,"0,0139372822",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"30,02",14
"low bq, low freq, many artifacts, many samples",UPN2_015,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),6138,76,6235,"0,0121892542",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"30,08","15,62"
"low bq, low freq, many artifacts, many samples",UPN2_016,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4193,74,4284,"0,0172735761",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"28,91","14,3"
"low bq, many samples",UPN2_017,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2992,71,3073,"0,0231044582",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"28,94","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_018,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4338,95,4442,"0,0213867627",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"29,02","14,07"
"low bq, low freq, many artifacts, many samples",UPN2_019,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4103,55,4169,"0,0131926121",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"29,95",14
"low bq, low freq, many artifacts, many samples",UPN2_020,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4257,91,4360,"0,0208715596",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"28,13","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_021,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4921,94,5029,"0,0186915888",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"28,2","14,14"
"low bq, many samples",UPN2_002,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4614,161,4803,"0,0335207162",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"28,18","14,08"
"low bq, low freq, many artifacts, many samples",UPN2_022,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3962,75,4052,"0,0185093781",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"28,69","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_023,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4500,52,4566,"0,0113885239",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"30,16","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_024,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2761,35,2803,"0,0124866215",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"28,9",14
"low bq, low freq, many artifacts, many samples",UPN2_025,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7103,114,7237,"0,0157523836",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"29,12","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_026,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),8599,177,8798,"0,0201182087",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"28,08","14,32"
"low bq, many samples",UPN2_004,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),831,37,876,"0,0422374429",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"27,93",14
"low bq, low freq, many artifacts, many samples",UPN2_027,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),8487,161,8684,"0,0185398434",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"29,07","14,51"
"low bq, many samples",UPN2_089,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4010,109,4137,"0,0263475949",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"28,74","14,06"
"low bq, bad alignment, many samples",UPN2_042,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),816,27,849,"0,0318021201",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"26,54",14
"low bq, low freq, many artifacts, many samples",UPN2_028,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),6185,117,6334,"0,0184717398",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"28,92","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_029,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4711,57,4787,"0,0119072488",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"30,05","16,49"
"low bq, low freq, many artifacts, many samples",UPN2_030,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1777,31,1815,"0,0170798898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"30,24","21,97"
"low bq, many samples",UPN2_005,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1104,29,1140,"0,0254385965",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"27,73",14
"low bq, bad alignment, many samples",UPN2_045,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3335,116,3478,"0,0333525014",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"26,28","14,47"
"low bq, bad alignment, many samples",UPN2_046,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3769,175,3971,"0,0440695039",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"26,4","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_033,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4785,90,4891,"0,018401145",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"29,13","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_034,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1980,36,2020,"0,0178217822",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"29,13","14,97"
"low bq, bad alignment, many samples",UPN2_047,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),864,34,906,"0,0375275938",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"26,56","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_036,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5116,52,5180,"0,01003861",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"29,99",14
"low bq, many samples",UPN2_006,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1760,68,1833,"0,0370976541",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"27,73","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_037,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7932,149,8102,"0,0183905209",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"28,69","14,58"
"low bq, bad alignment, many samples",UPN2_051,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3510,133,3669,"0,0362496593",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"26,2","14,41"
"low bq, bad alignment, many samples",UPN2_052,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7134,312,7483,"0,0416945076",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"26,1","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_038,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),10104,202,10330,"0,0195546951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"28,56","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_039,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4284,50,4349,"0,0114968958",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"29,68","14,88"
"low bq, bad alignment, many samples",UPN2_053,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),9851,387,10309,"0,0375400136",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"26,07","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_007,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),6807,141,6973,"0,0202208519",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"29,99","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_008,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),9998,223,10247,"0,0217624671",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"29,83","14,42"
"low bq, many samples",UPN2_009,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),10669,324,11021,"0,0293984212",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"28,46","14,34"
"low bq, many samples",UPN2_010,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5416,129,5561,"0,0231972667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"29,84","14,43"
"low bq, many samples",UPN2_011,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4445,102,4560,"0,0223684211",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"29,86","14,53"
"low bq, bad alignment, many samples",UPN2_055,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3318,136,3465,"0,0392496392",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"26,18","14,66"
"low bq, many samples",UPN2_012,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2731,89,2830,"0,0314487633",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"28,14","14,2"
"low bq, low freq, many artifacts, many samples",UPN2_040,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5422,99,5529,"0,0179055887",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"28,51","14,26"
"low bq, many samples",UPN2_013,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2237,92,2334,"0,0394173093",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"28,36","14,38"
"low bq, many samples",UPN2_093,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2593,68,2673,"0,025439581",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"29,21","14,81"
"low bq, many samples",UPN2_061,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),673,20,704,"0,0284090909",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"28,53",14
"low bq, bad alignment, many samples",UPN2_062,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2064,107,2191,"0,0488361479",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"26,56","14,51"
"low bq, bad alignment, many samples",UPN2_065,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),805,28,849,"0,0329799764",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"25,96","14,46"
"low bq, bad alignment, many samples",UPN2_066,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5957,244,6249,"0,0390462474",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"26,19","14,58"
"low bq, many samples",UPN2_067,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),608,23,635,"0,0362204724",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"28,48",14
"low bq, low freq, many artifacts, many samples",UPN2_068,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1054,20,1081,"0,0185013876",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"28,71","14,35"
"low bq, many samples",UPN2_069,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1322,41,1372,"0,0298833819",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"29,09","14,76"
"low bq, bad alignment, many samples",UPN2_071,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1672,96,1778,"0,0539932508",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"26,19","15,3"
"low bq, bad alignment, many samples",UPN2_073,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),760,27,793,"0,0340479193",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"26,38","14,48"
"low bq, bad alignment, many samples",UPN2_074,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5150,246,5454,"0,0451045105",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"25,87","14,72"
"low bq, bad alignment, many samples",UPN2_075,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3150,163,3337,"0,0488462691",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"26,38","14,48"
"low bq, bad alignment, many samples",UPN2_076,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3374,141,3540,"0,0398305085",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"26,68","14,55"
"low bq, bad alignment, many samples",UPN2_077,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7848,353,8270,"0,0426844015",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"26,2","14,45"
"low bq, bad alignment, many samples",UPN2_080,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1383,56,1454,"0,0385144429",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"26,2","14,32"
"low bq, bad alignment, many samples",UPN2_083,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4803,206,5049,"0,0408001584",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"26,61","14,64"
"low bq, bad alignment, many samples",UPN2_084,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),8740,385,9216,"0,0417751736",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"26,35","14,56"
"low bq, bad alignment, many samples",UPN2_086,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2799,117,2949,"0,0396744659",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"26,24","15,51"
"low bq, bad alignment, many samples",UPN2_087,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),8713,422,9220,"0,0457700651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"26,36","14,69"
"low bq, many samples",UPN2_094,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3376,103,3490,"0,029512894",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"28,45","14,48"
"low bq, many samples",UPN2_096,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3195,74,3275,"0,0225954198",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"28,95","14,27"
"low bq, many samples",UPN2_097,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2069,70,2146,"0,0326188257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"27,6","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_100,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2658,56,2720,"0,0205882353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"28,59","14,86"
"low bq, many samples",UPN2_101,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4165,135,4317,"0,0312717165",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"27,24","14,35"
"low bq, many samples",UPN2_102,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3900,89,4005,"0,0222222222",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"28,83","14,33"
"low bq, many samples",UPN2_103,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3978,144,4151,"0,034690436",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"27,17","15,15"
"low bq, many samples",UPN2_105,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),907,25,936,"0,0267094017",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"27,97","14,28"
"low bq, bad alignment, many samples",UPN2_106,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1303,65,1372,"0,0473760933",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"26,14","14,83"
"low bq, bad alignment, many samples",UPN2_107,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7056,295,7381,"0,0399674841",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"26,89","14,29"
"low bq, many samples",UPN2_108,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5198,202,5425,"0,037235023",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"27,31","14,55"
"low bq, many samples",UPN2_109,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5070,126,5209,"0,0241889038",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"28,86","15,29"
low bq,UPN2_111,7,148543677,G,T,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser44Tyr/c.131C>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5627,218,5872,"0,0371253406",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,45",Neutral,6,Damaging,"27,09","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_001,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1924,37,1969,"0,0187912646",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"32,85","15,97"
"low bq, low freq, many artifacts, many samples",UPN2_014,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3937,62,4018,"0,0154305625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"32,51","16,56"
"low bq, low freq, many artifacts, many samples",UPN2_015,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),6128,87,6236,"0,0139512508",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"32,82","15,75"
"low bq, low freq, many artifacts, many samples",UPN2_016,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4193,70,4286,"0,0163322445",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"31,54","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_017,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3008,53,3073,"0,0172469899",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"31,24","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_018,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4342,82,4442,"0,0184601531",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"31,38","16,43"
"low bq, low freq, many artifacts, many samples",UPN2_019,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4093,51,4170,"0,0122302158",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"32,73","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_020,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4249,88,4360,"0,0201834862",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"30,24","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_021,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4903,108,5033,"0,0214583747",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"30,56","15,63"
"low bq, low freq, many artifacts, many samples",UPN2_002,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4679,104,4803,"0,0216531335",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"31,09","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_022,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3945,89,4052,"0,021964462",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"30,86","15,88"
"low bq, low freq, many artifacts, many samples",UPN2_023,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4501,47,4568,"0,0102889667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"32,83","16,43"
"low bq, low freq, many artifacts, many samples",UPN2_024,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2750,40,2804,"0,0142653352",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"31,33","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_025,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7090,127,7241,"0,0175390139",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"31,39","15,54"
"low bq, low freq, many artifacts, many samples",UPN2_026,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),8586,172,8806,"0,0195321372",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"30,58","14,87"
"low bq, many samples",UPN2_004,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),846,24,876,"0,0273972603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"30,74","15,46"
"low bq, low freq, many artifacts, many samples",UPN2_027,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),8478,154,8686,"0,0177296799",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"31,55","16,56"
"low bq, low freq, many artifacts, many samples",UPN2_028,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),6176,131,6340,"0,0206624606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"31,35","16,24"
"low bq, low freq, many artifacts, many samples",UPN2_029,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4717,59,4787,"0,012325047",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"32,88","17,53"
"low bq, many samples",UPN2_005,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1109,28,1140,"0,0245614035",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"30,5","15,43"
"low bq, many samples",UPN2_045,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3354,94,3480,"0,0270114943",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"29,32","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_032,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1684,23,1712,"0,0134345794",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"32,74","14,96"
"low bq, many samples",UPN2_046,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3823,124,3974,"0,0312028183",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"29,44","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_033,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4778,90,4893,"0,0183936235",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"31,56","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_034,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1973,37,2020,"0,0183168317",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"31,76","14,95"
"low bq, many samples",UPN2_047,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),871,30,907,"0,033076075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"29,45","15,17"
"low bq, low freq, many artifacts, many samples",UPN2_036,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5054,95,5181,"0,0183362285",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"32,87","20,21"
"low bq, many samples",UPN2_006,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1771,55,1834,"0,0299890949",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"30,51","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_037,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7958,114,8108,"0,0140601875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"31,31","15,54"
"low bq, many samples",UPN2_051,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3534,103,3670,"0,0280653951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"29,28","14,98"
"low bq, many samples",UPN2_052,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7258,193,7494,"0,0257539365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"29,27","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_038,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),10126,157,10333,"0,0151940385",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"31,23","15,46"
"low bq, low freq, many artifacts, many samples",UPN2_039,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4293,48,4351,"0,0110319467",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"32,62","17,27"
"low bq, many samples",UPN2_053,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),9935,297,10320,"0,0287790698",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"29,47","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_007,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),6818,124,6973,"0,0177828768",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"32,61","17,16"
"low bq, low freq, many artifacts, many samples",UPN2_008,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),10021,165,10248,"0,0161007026",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"32,73","15,42"
"low bq, low freq, many artifacts, many samples",UPN2_009,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),10741,242,11029,"0,0219421525",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"31,1","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_010,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5447,95,5564,"0,0170740474",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"32,81","15,25"
"low bq, low freq, many artifacts, many samples",UPN2_011,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4471,85,4563,"0,0186280956",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"32,67","15,29"
"low bq, many samples",UPN2_055,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3361,83,3470,"0,0239193084",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"29,5","15,95"
"low bq, low freq, many artifacts, many samples",UPN2_090,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2547,33,2593,"0,0127265715",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"31,19","15,21"
"low bq, many samples",UPN2_012,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2723,94,2832,"0,0331920904",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"30,43","15,51"
"low bq, low freq, many artifacts, many samples",UPN2_040,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5416,92,5530,"0,016636528",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"31,24","16,29"
"low bq, many samples",UPN2_013,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2253,72,2336,"0,0308219178",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"30,83","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_091,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3422,61,3502,"0,0174186179",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"30,67","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_092,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2151,27,2180,"0,0123853211",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"31,79","16,44"
"low bq, low freq, many artifacts, many samples",UPN2_062,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2137,43,2194,"0,0195989061",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"29,57","16,47"
"low bq, many samples",UPN2_065,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),821,27,853,"0,0316529894",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"29,52",14
"low bq, low freq, many artifacts, many samples",UPN2_066,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),6079,121,6260,"0,0193290735",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"29,44","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_069,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1344,22,1372,"0,0160349854",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"32,39",14
"low bq, many samples",UPN2_071,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1722,40,1780,"0,0224719101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"29,21","15,32"
"low bq, many samples",UPN2_074,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5299,121,5464,"0,0221449488",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"29,42","14,82"
"low bq, many samples",UPN2_075,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3226,82,3345,"0,0245142003",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"29,53","15,07"
"low bq, many samples",UPN2_076,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3442,78,3544,"0,0220090293",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"29,42","15,41"
"low bq, many samples",UPN2_077,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7991,205,8279,"0,0247614446",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"29,39","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_080,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1405,30,1457,"0,0205902539",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"29,59","15,17"
"low bq, many samples",UPN2_083,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4898,114,5059,"0,0225340976",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"29,68","16,2"
"low bq, many samples",UPN2_084,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),8910,228,9240,"0,0246753247",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"29,47","15,31"
"low bq, many samples",UPN2_086,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2845,82,2954,"0,0277589709",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"29,42","15,39"
"low bq, many samples",UPN2_087,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),8962,206,9242,"0,0222895477",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"29,37","15,66"
"low bq, low freq, many artifacts, many samples",UPN2_095,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4624,61,4701,"0,0129759626",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"31,75","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_099,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3017,47,3087,"0,0152251377",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"30,73","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_101,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4254,45,4327,"0,0103998151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"31,93","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_103,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4092,45,4161,"0,010814708",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"31,89","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_104,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4685,57,4764,"0,0119647355",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"31,91","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_106,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1345,24,1378,"0,0174165457",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"31,02",14
"low bq, low freq, many artifacts, many samples",UPN2_107,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7259,102,7402,"0,0137800594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"31,54","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_108,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5346,60,5438,"0,0110334682",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"31,94","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_110,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5230,58,5310,"0,0109227872",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"31,94","15,21"
"low bq, low freq, many artifacts",UPN2_111,7,148543678,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser44Thr/c.130T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5798,61,5889,"0,0103582951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,534,Tolerated,"31,74","15,3"
"low bq, low freq, many artifacts, many samples",UPN2_045,7,148543679,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser43Arg/c.129T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3441,36,3489,"0,0103181427",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,71",Neutral,165,Tolerated,"32,51","16,58"
"low bq, low freq, many artifacts, many samples",UPN2_046,7,148543679,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser43Arg/c.129T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3922,42,3980,"0,0105527638",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,71",Neutral,165,Tolerated,"32,61","17,55"
"low bq, low freq, many artifacts, many samples",UPN2_052,7,148543679,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser43Arg/c.129T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7393,79,7505,"0,0105263158",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,71",Neutral,165,Tolerated,"32,66","16,44"
"low bq, low freq, many artifacts, many samples",UPN2_001,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1932,29,1970,"0,0147208122",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"32,09","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_015,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),6142,78,6238,"0,0125040077",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"31,82","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_016,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4195,86,4289,"0,020051294",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"29,89","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_017,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3018,50,3073,"0,0162707452",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"29,98","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_018,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4352,87,4447,"0,0195637508",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"30,25","14,49"
"low bq, many samples",UPN2_020,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4248,114,4368,"0,0260989011",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"29,04","14,18"
"low bq, low freq, many artifacts, many samples",UPN2_021,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4916,110,5035,"0,0218470705",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"28,96","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_002,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4711,89,4811,"0,0184992725",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"30,42","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_022,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3979,67,4060,"0,0165024631",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"29,35",14
"low bq, low freq, many artifacts, many samples",UPN2_023,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4510,51,4571,"0,011157296",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"31,64","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_024,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2752,51,2806,"0,0181753386",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"29,82","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_025,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7102,130,7246,"0,0179409329",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"30,08","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_026,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8623,170,8811,"0,0192940642",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"29,34","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_027,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8533,127,8692,"0,0146111367",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"30,26","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_089,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4076,56,4142,"0,0135200386",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"31,51","14,36"
"low bq, many samples",UPN2_042,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),821,29,853,"0,0339976553",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"28,24","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_028,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),6241,95,6345,"0,0149724192",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"30,27","14,67"
"low bq, many samples",UPN2_005,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1111,28,1141,"0,0245398773",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"29,98","16,75"
"low bq, many samples",UPN2_045,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3382,100,3492,"0,0286368843",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"27,85","14,35"
"low bq, many samples",UPN2_046,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3858,117,3983,"0,0293748431",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,28,"14,75"
"low bq, low freq, many artifacts, many samples",UPN2_033,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4803,87,4900,"0,017755102",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"29,96","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_034,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1995,27,2025,"0,0133333333",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"30,42","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_036,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5121,57,5185,"0,0109932498",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"31,69","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_006,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1794,39,1837,"0,0212302667",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"29,91","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_037,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7970,129,8114,"0,0158984471",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"30,21","14,11"
"low bq, many samples",UPN2_052,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7256,227,7508,"0,0302344166",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"27,9","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_038,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10173,166,10348,"0,0160417472",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"30,02","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_007,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),6881,82,6977,"0,0117529024",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"31,59","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_008,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10103,126,10250,"0,0122926829",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"31,91","15,58"
"low bq, low freq, many artifacts, many samples",UPN2_009,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10766,237,11038,"0,021471281",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"30,67","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_010,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5493,63,5568,"0,0113146552",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"31,88","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_011,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4492,48,4568,"0,0105078809",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"31,61","15,27"
"low bq, many samples",UPN2_055,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3360,106,3478,"0,0304772858",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"27,97","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_090,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2543,52,2600,"0,02",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"29,27","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_040,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5426,89,5531,"0,0160911228",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"30,27","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_091,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3428,75,3513,"0,0213492741",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"28,74","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_092,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2143,39,2187,"0,0178326475",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"29,9","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_093,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2624,32,2674,"0,0119670905",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"31,93","14,62"
"low bq, many samples",UPN2_062,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2138,52,2200,"0,0236363636",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"29,39","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_066,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),6122,122,6274,"0,0194453299",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"28,73","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_069,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1340,26,1372,"0,0189504373",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"31,24",14
"low bq, many samples",UPN2_071,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1734,43,1784,"0,024103139",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"28,37","14,84"
"low bq, many samples",UPN2_073,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),773,25,798,"0,0313283208",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"29,06","14,52"
"low bq, many samples",UPN2_074,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5323,138,5483,"0,0251687033",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"28,79","14,77"
"low bq, many samples",UPN2_075,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3240,99,3354,"0,0295169946",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"28,78","14,69"
"low bq, many samples",UPN2_076,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3446,92,3552,"0,0259009009",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"28,99","14,68"
"low bq, many samples",UPN2_077,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8041,217,8295,"0,0261603376",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"28,82","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_080,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1423,27,1462,"0,0184678523",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"28,78","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_083,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4956,94,5071,"0,0185367778",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"29,12","14,59"
"low bq, many samples",UPN2_084,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),9002,239,9268,"0,0257876565",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"28,82","14,57"
"low bq, many samples",UPN2_087,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8992,236,9269,"0,0254612148",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"28,8","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_094,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3446,46,3499,"0,0131466133",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"31,14","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_095,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4619,77,4706,"0,0163620909",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"29,99","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_097,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2118,32,2154,"0,0148560817",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"30,56","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_099,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3028,61,3095,"0,0197092084",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"28,75","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_101,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4260,60,4337,"0,0138344478",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,30,"14,45"
"low bq, low freq, many artifacts, many samples",UPN2_102,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3951,49,4009,"0,0122224994",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"31,7","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_103,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4083,76,4174,"0,018207954",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"30,22","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_104,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4686,83,4782,"0,0173567545",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"30,03","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_107,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7277,113,7418,"0,0152332165",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"29,86","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_108,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5337,91,5448,"0,0167033774",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"29,97","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_110,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5236,75,5324,"0,0140871525",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"29,99","14,52"
"low bq, low freq, many artifacts",UPN2_111,7,148543680,C,A,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser43Ile/c.128G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5796,95,5904,"0,0160907859",0,0,0,0,1,0,0,0,1,NO,NO,COSM3879126. COSM3879127,stomach,2,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,484,Tolerated,"30,08","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_018,7,148543681,T,A,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser43Cys/c.127A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4397,47,4449,"0,0105641717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,99,Tolerated,"30,32","19,06"
"low bq, low freq, many artifacts, many samples",UPN2_022,7,148543681,T,A,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser43Cys/c.127A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4013,41,4063,"0,0100910657",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,99,Tolerated,"29,49","15,61"
"low bq, low freq, many artifacts, many samples",UPN2_026,7,148543681,T,A,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser43Cys/c.127A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8691,114,8823,"0,0129207752",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,99,Tolerated,"29,26","16,84"
"low bq, low freq, many artifacts, many samples",UPN2_028,7,148543681,T,A,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser43Cys/c.127A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),6247,73,6347,"0,0115014968",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,99,Tolerated,"29,92","17,59"
"low bq, low freq, many artifacts, many samples",UPN2_045,7,148543681,T,A,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser43Cys/c.127A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3431,62,3502,"0,017704169",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,99,Tolerated,"28,02","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_046,7,148543681,T,A,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser43Cys/c.127A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3887,81,3986,"0,0203211239",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,99,Tolerated,"28,17","16,56"
"low bq, low freq, many artifacts, many samples",UPN2_051,7,148543681,T,A,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser43Cys/c.127A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3608,67,3684,"0,0181867535",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,99,Tolerated,"28,07","15,96"
"low bq, low freq, many artifacts, many samples",UPN2_052,7,148543681,T,A,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser43Cys/c.127A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7371,130,7523,"0,0172803403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,99,Tolerated,"28,32","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_038,7,148543681,T,A,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser43Cys/c.127A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10221,105,10351,"0,0101439474",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,99,Tolerated,"30,03","17,82"
"low bq, low freq, many artifacts, many samples",UPN2_053,7,148543681,T,A,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser43Cys/c.127A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10111,208,10362,"0,0200733449",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,99,Tolerated,"28,27","16,48"
"low bq, low freq, many artifacts, many samples",UPN2_009,7,148543681,T,A,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser43Cys/c.127A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10916,117,11051,"0,0105872772",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,99,Tolerated,"30,66","15,56"
"low bq, low freq, many artifacts, many samples",UPN2_055,7,148543681,T,A,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser43Cys/c.127A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3412,65,3483,"0,0186620729",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,99,Tolerated,"28,31","15,4"
"low bq, low freq, many artifacts, many samples",UPN2_013,7,148543681,T,A,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser43Cys/c.127A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2311,25,2340,"0,0106837607",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,99,Tolerated,"30,37","15,76"
"low bq, low freq, many artifacts, many samples",UPN2_062,7,148543681,T,A,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser43Cys/c.127A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2167,32,2205,"0,0145124717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,99,Tolerated,"29,19","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_066,7,148543681,T,A,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser43Cys/c.127A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),6181,88,6288,"0,0139949109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,99,Tolerated,"29,16","17,18"
"low bq, low freq, many artifacts, many samples",UPN2_071,7,148543681,T,A,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser43Cys/c.127A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1754,21,1786,"0,0117581187",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,99,Tolerated,"28,79","16,1"
"low bq, low freq, many artifacts, many samples",UPN2_074,7,148543681,T,A,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser43Cys/c.127A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5410,73,5496,"0,0132823872",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,99,Tolerated,"28,73","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_075,7,148543681,T,A,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser43Cys/c.127A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3303,48,3360,"0,0142857143",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,99,Tolerated,"29,43","16,21"
"low bq, low freq, many artifacts, many samples",UPN2_076,7,148543681,T,A,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser43Cys/c.127A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3495,50,3559,"0,0140488901",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,99,Tolerated,"29,09","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_077,7,148543681,T,A,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser43Cys/c.127A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8152,123,8305,"0,0148103552",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,99,Tolerated,"29,14","16,29"
"low bq, low freq, many artifacts, many samples",UPN2_080,7,148543681,T,A,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser43Cys/c.127A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1438,22,1464,"0,0150273224",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,99,Tolerated,"29,02",16
"low bq, low freq, many artifacts, many samples",UPN2_083,7,148543681,T,A,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser43Cys/c.127A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4994,63,5072,"0,0124211356",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,99,Tolerated,"29,29","16,73"
"low bq, low freq, many artifacts, many samples",UPN2_084,7,148543681,T,A,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser43Cys/c.127A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),9131,122,9281,"0,0131451352",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,99,Tolerated,29,"16,13"
"low bq, low freq, many artifacts, many samples",UPN2_086,7,148543681,T,A,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser43Cys/c.127A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2920,37,2966,"0,0124747134",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,99,Tolerated,"28,93","15,49"
"low bq, low freq, many artifacts",UPN2_087,7,148543681,T,A,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser43Cys/c.127A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),9138,118,9285,"0,0127086699",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,99,Tolerated,"29,38","15,79"
"low bq, low freq, many artifacts, many samples",UPN2_001,7,148543682,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe42Leu/c.126T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1936,30,1971,"0,0152207002",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,152,Tolerated,"33,51","19,77"
"low bq, low freq, many artifacts, many samples",UPN2_016,7,148543682,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe42Leu/c.126T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4220,46,4291,"0,0107201119",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,152,Tolerated,"33,4","16,28"
"low bq, low freq, many artifacts, many samples",UPN2_018,7,148543682,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe42Leu/c.126T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4372,56,4450,"0,0125842697",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,152,Tolerated,"33,49","17,62"
"low bq, low freq, many artifacts, many samples",UPN2_020,7,148543682,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe42Leu/c.126T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4288,65,4371,"0,014870739",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,152,Tolerated,"32,83","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_021,7,148543682,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe42Leu/c.126T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4970,51,5043,"0,010113028",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,152,Tolerated,"33,02","16,04"
"low bq, low freq, many artifacts, many samples",UPN2_002,7,148543682,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe42Leu/c.126T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4748,59,4819,"0,012243204",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,152,Tolerated,"33,06","15,8"
"low bq, low freq, many artifacts, many samples",UPN2_024,7,148543682,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe42Leu/c.126T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2757,37,2807,"0,0131813324",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,152,Tolerated,"33,19","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_025,7,148543682,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe42Leu/c.126T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7133,78,7251,"0,0107571369",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,152,Tolerated,"33,49","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_026,7,148543682,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe42Leu/c.126T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),8687,96,8826,"0,0108769545",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,152,Tolerated,"33,1","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_045,7,148543682,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe42Leu/c.126T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3418,66,3505,"0,0188302425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,152,Tolerated,"31,8","15,35"
"low bq, many samples",UPN2_046,7,148543682,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe42Leu/c.126T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3879,91,3988,"0,0228184554",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,152,Tolerated,"31,97","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_033,7,148543682,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe42Leu/c.126T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4824,55,4905,"0,0112130479",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,152,Tolerated,"33,25","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_036,7,148543682,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe42Leu/c.126T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5097,55,5186,"0,0106054763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,152,Tolerated,"34,03","16,35"
"low bq, low freq, many artifacts, many samples",UPN2_006,7,148543682,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe42Leu/c.126T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1807,24,1840,"0,0130434783",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,152,Tolerated,"33,03","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_051,7,148543682,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe42Leu/c.126T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3601,65,3686,"0,0176342919",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,152,Tolerated,"31,92",15
"low bq, low freq, many artifacts, many samples",UPN2_052,7,148543682,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe42Leu/c.126T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7353,125,7526,"0,0166090885",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,152,Tolerated,"32,08","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_038,7,148543682,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe42Leu/c.126T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),10181,113,10355,"0,0109126026",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,152,Tolerated,"33,41","15,95"
"low bq, low freq, many artifacts, many samples",UPN2_053,7,148543682,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe42Leu/c.126T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),10124,188,10371,"0,0181274708",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,152,Tolerated,"31,97","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_009,7,148543682,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe42Leu/c.126T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),10862,140,11054,"0,0126650986",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,152,Tolerated,"32,99","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_011,7,148543682,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe42Leu/c.126T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4508,49,4572,"0,0107174103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,152,Tolerated,"33,47","17,43"
"low bq, low freq, many artifacts, many samples",UPN2_055,7,148543682,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe42Leu/c.126T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3410,65,3488,"0,0186353211",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,152,Tolerated,"32,11","16,74"
"low bq, low freq, many artifacts, many samples",UPN2_012,7,148543682,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe42Leu/c.126T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2795,32,2837,"0,0112795206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,152,Tolerated,"32,77","15,84"
"low bq, low freq, many artifacts, many samples",UPN2_040,7,148543682,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe42Leu/c.126T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5449,59,5531,"0,0106671488",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,152,Tolerated,"33,6","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_013,7,148543682,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe42Leu/c.126T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2294,40,2341,"0,0170867151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,152,Tolerated,"32,97",14
"low bq, low freq, many artifacts, many samples",UPN2_062,7,148543682,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe42Leu/c.126T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2168,33,2206,"0,0149592022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,152,Tolerated,"31,99",14
"low bq, low freq, many artifacts, many samples",UPN2_066,7,148543682,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe42Leu/c.126T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),6174,82,6292,"0,0130324221",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,152,Tolerated,"31,88","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_071,7,148543682,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe42Leu/c.126T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1753,27,1786,"0,0151175812",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,152,Tolerated,"31,92",14
"low bq, low freq, many artifacts, many samples",UPN2_074,7,148543682,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe42Leu/c.126T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5385,88,5497,"0,016008732",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,152,Tolerated,"31,74",15
"low bq, low freq, many artifacts, many samples",UPN2_075,7,148543682,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe42Leu/c.126T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3309,44,3364,"0,0130796671",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,152,Tolerated,"31,75","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_076,7,148543682,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe42Leu/c.126T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3511,38,3563,"0,0106651698",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,152,Tolerated,"31,81","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_077,7,148543682,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe42Leu/c.126T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),8168,108,8310,"0,0129963899",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,152,Tolerated,"31,82","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_080,7,148543682,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe42Leu/c.126T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1432,27,1465,"0,0184300341",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,152,Tolerated,"32,11","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_083,7,148543682,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe42Leu/c.126T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4980,66,5077,"0,012999803",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,152,Tolerated,32,"15,33"
"low bq, low freq, many artifacts, many samples",UPN2_084,7,148543682,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe42Leu/c.126T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),9090,149,9288,"0,016042205",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,152,Tolerated,"31,91","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_086,7,148543682,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe42Leu/c.126T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2906,45,2967,"0,0151668352",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,152,Tolerated,"31,83","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_087,7,148543682,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe42Leu/c.126T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),9096,152,9296,"0,0163511188",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,152,Tolerated,"31,84","14,87"
"low bq, low freq, many artifacts",UPN2_099,7,148543682,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe42Leu/c.126T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3056,32,3098,"0,0103292447",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,152,Tolerated,"32,71","16,62"
"low bq, low freq, many artifacts, many samples",UPN2_045,7,148543683,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe42Tyr/c.125T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3459,40,3511,"0,0113927656",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,15",Neutral,642,Tolerated,"33,27","15,9"
"low bq, low freq, many artifacts, many samples",UPN2_051,7,148543683,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe42Tyr/c.125T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3628,37,3688,"0,010032538",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,15",Neutral,642,Tolerated,"33,32","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_055,7,148543684,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe42Ile/c.124T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3424,39,3490,"0,0111747851",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,6,Damaging,"32,79","20,67"
"low bq, low freq, many artifacts",UPN2_013,7,148543684,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe42Ile/c.124T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2303,27,2342,"0,011528608",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,6,Damaging,"33,5","18,04"
"low bq, low freq, many artifacts, many samples",UPN2_001,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1942,24,1971,"0,0121765601",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"31,27","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_014,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3969,45,4024,"0,0111829026",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"31,38","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_016,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4204,73,4292,"0,0170083877",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"29,9",14
"low bq, low freq, many artifacts, many samples",UPN2_017,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3013,58,3079,"0,0188372848",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"29,98","14,12"
"low bq, low freq, many artifacts, many samples",UPN2_018,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4363,73,4451,"0,0164008088",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"29,95","14,4"
"low bq, many samples",UPN2_020,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4259,100,4377,"0,0228466987",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"28,66","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_021,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4932,100,5047,"0,0198137507",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"28,75","14,18"
"low bq, low freq, many artifacts, many samples",UPN2_002,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4710,104,4821,"0,0215722879",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"30,05","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_022,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3991,64,4065,"0,0157441574",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"29,32",14
"low bq, low freq, many artifacts, many samples",UPN2_023,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4513,47,4571,"0,010282214",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"31,67","15,49"
"low bq, low freq, many artifacts, many samples",UPN2_024,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2749,51,2809,"0,0181559274",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"29,46","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_025,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7119,117,7258,"0,0161201433",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"30,08","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_026,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8632,175,8832,"0,0198143116",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"29,07","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_027,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8542,128,8700,"0,0147126437",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"30,23","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_089,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4067,55,4142,"0,0132786094",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"30,98","14,24"
"low bq, many samples",UPN2_042,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),829,24,858,"0,027972028",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"27,77",14
"low bq, low freq, many artifacts, many samples",UPN2_028,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),6242,94,6352,"0,0147984887",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"30,01","14,54"
"low bq, many samples",UPN2_005,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1114,26,1144,"0,0227272727",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"29,35","14,27"
"low bq, many samples",UPN2_045,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3364,118,3513,"0,0335895246",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"27,34","14,46"
"low bq, many samples",UPN2_046,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3822,149,3992,"0,0373246493",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"27,52","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_033,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4825,64,4905,"0,0130479103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"29,92",14
"low bq, low freq, many artifacts, many samples",UPN2_034,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1986,35,2026,"0,0172754195",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"30,28",14
"low bq, many samples",UPN2_047,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),878,31,911,"0,0340285401",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"27,7",14
"low bq, low freq, many artifacts, many samples",UPN2_006,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1799,35,1843,"0,0189907759",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"29,35","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_037,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7999,122,8136,"0,0149950836",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"30,05","14,21"
"low bq, many samples",UPN2_051,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3534,139,3692,"0,0376489707",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"27,18","14,25"
"low bq, many samples",UPN2_052,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7265,233,7542,"0,0308936622",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"27,44","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_038,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10168,161,10360,"0,0155405405",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"29,93","14,11"
"low bq, many samples",UPN2_053,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10005,329,10384,"0,031683359",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"27,43","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_007,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),6863,95,6980,"0,0136103152",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"31,29","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_008,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10106,130,10254,"0,0126779793",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"31,55","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_009,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10802,219,11070,"0,0197831978",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"29,98","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_010,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5500,62,5575,"0,0111210762",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"31,55","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_011,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4501,60,4574,"0,0131176213",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"31,31","14,33"
"low bq, many samples",UPN2_055,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3365,108,3491,"0,0309366944",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"27,54","14,33"
"low bq, many samples",UPN2_090,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2511,73,2605,"0,0280230326",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,29,"14,27"
"low bq, low freq, many artifacts, many samples",UPN2_012,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2770,59,2838,"0,0207892882",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"29,39","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_040,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5420,88,5533,"0,0159045726",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"29,92","14,16"
"low bq, many samples",UPN2_013,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2271,55,2343,"0,0234741784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"29,39","14,45"
"low bq, many samples",UPN2_091,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3415,89,3523,"0,0252625603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"28,31","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_092,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2139,45,2190,"0,0205479452",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"29,32","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_093,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2639,28,2675,"0,0104672897",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"31,53",14
"low bq, many samples",UPN2_062,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2131,65,2213,"0,0293718934",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"28,4","14,11"
"low bq, many samples",UPN2_066,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),6034,226,6307,"0,0358332012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"28,15","14,42"
"low bq, many samples",UPN2_069,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1334,32,1373,"0,0233066278",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"30,83","14,41"
"low bq, many samples",UPN2_071,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1696,75,1788,"0,0419463087",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"27,83","14,09"
"low bq, many samples",UPN2_073,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),768,27,803,"0,0336239103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"27,9","14,93"
"low bq, many samples",UPN2_074,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5296,166,5506,"0,0301489284",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"27,88","14,04"
"low bq, many samples",UPN2_075,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3240,103,3372,"0,0305456702",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"27,85","14,83"
"low bq, many samples",UPN2_076,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3436,101,3568,"0,0283071749",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"28,2","14,82"
"low bq, many samples",UPN2_077,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8005,254,8322,"0,0305215093",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"27,96","14,31"
"low bq, many samples",UPN2_080,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1415,39,1467,"0,0265848671",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"27,72",14
"low bq, many samples",UPN2_083,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4914,130,5091,"0,0255352583",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"28,25","14,65"
"low bq, many samples",UPN2_084,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8945,291,9295,"0,0313071544",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"27,86","14,69"
"low bq, many samples",UPN2_086,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2848,105,2971,"0,0353416358",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"27,92","14,6"
"low bq, many samples",UPN2_087,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8938,291,9305,"0,0312735089",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"27,86","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_094,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3443,49,3504,"0,0139840183",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"30,59","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_095,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4587,101,4713,"0,021430087",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"29,32","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_096,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3242,36,3288,"0,0109489051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"31,19","14,19"
"low bq, low freq, many artifacts, many samples",UPN2_097,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2116,30,2159,"0,0138953219",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"30,02","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_099,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3016,68,3099,"0,0219425621",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"28,18","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_100,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2683,37,2727,"0,0135680235",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"31,3",14
"low bq, low freq, many artifacts, many samples",UPN2_101,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4252,63,4342,"0,0145094427",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"29,62","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_103,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4084,74,4182,"0,0176948828",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"29,32",14
"low bq, low freq, many artifacts, many samples",UPN2_104,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4672,89,4792,"0,018572621",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"29,34",14
"low bq, low freq, many artifacts, many samples",UPN2_106,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1351,28,1385,"0,0202166065",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"28,3","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_107,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7224,153,7429,"0,0205949657",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"29,13","14,2"
"low bq, low freq, many artifacts, many samples",UPN2_108,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5321,111,5457,"0,0203408466",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"29,47","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_109,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5150,58,5227,"0,0110962311",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"31,59","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_110,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5190,110,5334,"0,0206224222",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"29,61","14,65"
"low bq, low freq, many artifacts",UPN2_111,7,148543685,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met41Ile/c.123G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5779,122,5929,"0,0205768258",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,3",Tolerated,"29,39","14,2"
"low freq, many artifacts",UPN2_062,7,148543686,A,G,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met41Thr/c.122T>C|751|EZH2|protein_coding|CODING|ENST00000320356|3|G),2167,23,2220,"0,0103603604",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,"0,022",Damaging,"30,8","27,83"
"low bq, low freq, many artifacts, many samples",UPN2_045,7,148543686,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met41Lys/c.122T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3465,38,3525,"0,0107801418",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,5",Neutral,"0,01",Damaging,"30,07","17,71"
"low bq, low freq, many artifacts, many samples",UPN2_046,7,148543686,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met41Lys/c.122T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3920,49,3996,"0,0122622623",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,5",Neutral,"0,01",Damaging,"30,04","18,86"
"low bq, low freq, many artifacts, many samples",UPN2_052,7,148543686,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met41Lys/c.122T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7432,82,7556,"0,0108523028",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,5",Neutral,"0,01",Damaging,"30,29","17,54"
"low bq, low freq, many artifacts, many samples",UPN2_053,7,148543686,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met41Lys/c.122T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),10207,138,10400,"0,0132692308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,5",Neutral,"0,01",Damaging,"30,13","18,54"
"low bq, low freq, many artifacts, many samples",UPN2_012,7,148543686,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met41Lys/c.122T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2789,39,2840,"0,0137323944",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,5",Neutral,"0,01",Damaging,"31,55","15,92"
"low bq, low freq, many artifacts, many samples",UPN2_077,7,148543686,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met41Lys/c.122T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),8212,85,8340,"0,0101918465",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,5",Neutral,"0,01",Damaging,"30,71","17,41"
"low bq, low freq, many artifacts, many samples",UPN2_083,7,148543686,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met41Lys/c.122T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5013,54,5102,"0,0105840847",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,5",Neutral,"0,01",Damaging,"31,03","16,2"
"low bq, low freq, many artifacts, many samples",UPN2_086,7,148543686,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met41Lys/c.122T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2927,38,2977,"0,012764528",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,5",Neutral,"0,01",Damaging,"30,59","19,32"
"low bq, low freq, many artifacts",UPN2_087,7,148543686,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met41Lys/c.122T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),9165,100,9321,"0,0107284626",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,5",Neutral,"0,01",Damaging,"30,96","16,12"
"low bq, low freq, many artifacts, many samples",UPN2_016,7,148543687,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met41Leu/c.121A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4236,46,4296,"0,010707635",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,1,Tolerated,"29,79","16,78"
"low bq, low freq, many artifacts, many samples",UPN2_002,7,148543687,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met41Leu/c.121A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4765,51,4823,"0,0105743313",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,1,Tolerated,"30,02","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_026,7,148543687,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met41Leu/c.121A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8721,107,8850,"0,0120903955",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,1,Tolerated,"28,91","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_028,7,148543687,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met41Leu/c.121A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),6277,67,6359,"0,0105362478",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,1,Tolerated,"29,69","15,97"
"low bq, low freq, many artifacts, many samples",UPN2_045,7,148543687,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met41Leu/c.121A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3452,68,3526,"0,0192853091",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,1,Tolerated,"27,67","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_046,7,148543687,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met41Leu/c.121A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3929,61,3998,"0,0152576288",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,1,Tolerated,"27,83","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_047,7,148543687,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met41Leu/c.121A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),892,20,913,"0,021905805",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,1,Tolerated,"27,29","15,45"
"low bq, low freq, many artifacts, many samples",UPN2_051,7,148543687,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met41Leu/c.121A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3632,63,3703,"0,0170132325",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,1,Tolerated,"27,98","15,89"
"low bq, low freq, many artifacts, many samples",UPN2_052,7,148543687,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met41Leu/c.121A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7408,134,7560,"0,0177248677",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,1,Tolerated,"27,95","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_053,7,148543687,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met41Leu/c.121A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10211,175,10402,"0,0168236878",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,1,Tolerated,"27,91","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_055,7,148543687,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met41Leu/c.121A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3434,56,3502,"0,0159908624",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,1,Tolerated,"27,89","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_062,7,148543687,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met41Leu/c.121A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2169,32,2220,"0,0144144144",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,1,Tolerated,"28,21",14
"low bq, low freq, many artifacts, many samples",UPN2_066,7,148543687,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met41Leu/c.121A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),6217,92,6320,"0,014556962",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,1,Tolerated,"28,23","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_071,7,148543687,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met41Leu/c.121A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1753,34,1789,"0,0190050307",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,1,Tolerated,"28,05","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_074,7,148543687,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met41Leu/c.121A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5392,114,5518,"0,0206596593",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,1,Tolerated,"28,02","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_075,7,148543687,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met41Leu/c.121A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3327,43,3381,"0,0127181307",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,1,Tolerated,"28,3","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_076,7,148543687,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met41Leu/c.121A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3514,58,3578,"0,0162101733",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,1,Tolerated,"27,87","15,52"
"low bq, low freq, many artifacts, many samples",UPN2_077,7,148543687,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met41Leu/c.121A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8180,147,8345,"0,0176153385",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,1,Tolerated,"28,25","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_080,7,148543687,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met41Leu/c.121A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1445,23,1471,"0,015635622",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,1,Tolerated,"28,03",14
"low bq, low freq, many artifacts, many samples",UPN2_083,7,148543687,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met41Leu/c.121A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5021,75,5105,"0,0146914789",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,1,Tolerated,"28,55","15,65"
"low bq, low freq, many artifacts, many samples",UPN2_084,7,148543687,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met41Leu/c.121A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),9112,191,9317,"0,020500161",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,1,Tolerated,28,"15,5"
"low bq, low freq, many artifacts, many samples",UPN2_086,7,148543687,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met41Leu/c.121A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2924,47,2977,"0,0157877057",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,1,Tolerated,"28,26","16,64"
"low bq, low freq, many artifacts",UPN2_087,7,148543687,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met41Leu/c.121A>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),9148,163,9325,"0,0174798928",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,1,Tolerated,"28,26","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_001,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1942,27,1972,"0,0136916836",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"33,4","17,26"
"low bq, low freq, many artifacts, many samples",UPN2_014,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3977,44,4026,"0,0109289617",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"33,46","16,5"
"low bq, low freq, many artifacts, many samples",UPN2_016,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4233,57,4297,"0,0132650687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"32,94","16,32"
"low bq, low freq, many artifacts, many samples",UPN2_017,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3036,37,3082,"0,0120051914",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"32,98","16,86"
"low bq, low freq, many artifacts, many samples",UPN2_018,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4384,68,4458,"0,0152534769",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"33,01","17,72"
"low bq, low freq, many artifacts, many samples",UPN2_020,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4309,65,4381,"0,0148367953",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"32,53","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_021,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4965,83,5056,"0,0164161392",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"32,56","15,98"
"low bq, low freq, many artifacts, many samples",UPN2_002,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4747,65,4823,"0,0134770889",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"32,65","15,63"
"low bq, low freq, many artifacts, many samples",UPN2_022,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3996,59,4066,"0,0145105755",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"32,76","16,46"
"low bq, low freq, many artifacts, many samples",UPN2_023,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4506,56,4573,"0,0122457905",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"33,56","17,3"
"low bq, low freq, many artifacts, many samples",UPN2_024,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2780,33,2815,"0,011722913",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"32,96","16,39"
"low bq, low freq, many artifacts, many samples",UPN2_025,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7158,88,7266,"0,0121112029",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"33,04","16,39"
"low bq, low freq, many artifacts, many samples",UPN2_026,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),8721,110,8850,"0,0124293785",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"32,66","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_027,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),8575,116,8707,"0,013322614",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"33,01","15,92"
"low bq, many samples",UPN2_042,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),831,23,860,"0,026744186",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"31,49","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_028,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),6265,75,6360,"0,0117924528",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"32,89","16,35"
"low bq, low freq, many artifacts, many samples",UPN2_029,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4723,62,4794,"0,0129328327",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"33,71","17,63"
"low bq, many samples",UPN2_045,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3414,101,3526,"0,0286443562",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"31,36","17,29"
"low bq, low freq, many artifacts, many samples",UPN2_032,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1687,23,1714,"0,0134189032",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"33,34","15,91"
"low bq, many samples",UPN2_046,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3887,106,4000,"0,0265",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"31,29","16,06"
"low bq, low freq, many artifacts, many samples",UPN2_033,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4829,74,4913,"0,0150620802",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"33,05","15,92"
"low bq, low freq, many artifacts, many samples",UPN2_034,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1996,26,2028,"0,0128205128",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"32,85","17,73"
"low bq, many samples",UPN2_047,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),887,24,913,"0,026286966",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"31,19",14
"low bq, low freq, many artifacts, many samples",UPN2_036,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5122,57,5187,"0,010989011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"33,56","16,75"
"low bq, low freq, many artifacts, many samples",UPN2_006,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1805,33,1844,"0,0178958785",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"32,61","17,36"
"low bq, low freq, many artifacts, many samples",UPN2_037,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),8036,94,8142,"0,0115450749",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"32,96","16,35"
"low bq, many samples",UPN2_051,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3603,89,3704,"0,0240280778",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"31,46","15,89"
"low bq, low freq, many artifacts, many samples",UPN2_052,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7389,154,7562,"0,0203649828",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"31,29","15,37"
"low bq, low freq, many artifacts, many samples",UPN2_038,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),10222,132,10374,"0,012724118",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"32,93","15,83"
"low bq, low freq, many artifacts, many samples",UPN2_039,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4297,49,4354,"0,0112540193",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"33,64","19,86"
"low bq, many samples",UPN2_053,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),10105,268,10404,"0,0257593233",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"31,2","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_007,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),6849,107,6983,"0,0153229271",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"33,34","17,29"
"low bq, low freq, many artifacts, many samples",UPN2_008,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),10111,122,10257,"0,0118943161",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"33,28","15,94"
"low bq, low freq, many artifacts, many samples",UPN2_009,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),10892,168,11084,"0,015156983",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"32,62","15,73"
"low bq, low freq, many artifacts, many samples",UPN2_010,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5499,67,5576,"0,0120157819",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"33,27","15,91"
"low bq, low freq, many artifacts, many samples",UPN2_011,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4502,70,4576,"0,0152972028",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"33,33","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_055,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3424,68,3504,"0,0194063927",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"31,32","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_090,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2562,44,2612,"0,0168453292",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"32,05","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_012,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2776,62,2844,"0,0218002813",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"32,34","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_040,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5449,76,5538,"0,0137233658",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"32,95","16,84"
"low bq, low freq, many artifacts, many samples",UPN2_013,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2299,46,2348,"0,0195911414",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"32,37","16,78"
"low bq, low freq, many artifacts, many samples",UPN2_091,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3463,57,3530,"0,0161473088",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"31,93","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_092,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2162,32,2199,"0,0145520691",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"32,32","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_062,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2178,38,2222,"0,0171017102",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"30,92","16,21"
"low bq, many samples",UPN2_065,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),834,25,863,"0,0289687138",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"30,8","15,4"
"low bq, low freq, many artifacts, many samples",UPN2_066,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),6172,136,6322,"0,0215121797",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"30,8","15,46"
"low bq, low freq, many artifacts, many samples",UPN2_071,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1748,39,1790,"0,0217877095",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"30,58","15,79"
"low bq, low freq, many artifacts, many samples",UPN2_074,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5383,118,5521,"0,0213729397",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"30,59","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_075,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3301,69,3381,"0,0204081633",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"30,75","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_076,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3511,58,3579,"0,016205644",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"30,67","15,6"
"low bq, many samples",UPN2_077,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),8139,196,8350,"0,0234730539",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"30,78","15,94"
"low bq, low freq, many artifacts, many samples",UPN2_080,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),1436,31,1471,"0,0210740993",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"31,09","16,13"
"low bq, low freq, many artifacts, many samples",UPN2_083,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5000,97,5111,"0,0189786734",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"30,87","14,79"
"low bq, many samples",UPN2_084,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),9086,207,9321,"0,0222079176",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"30,81","15,32"
"low bq, many samples",UPN2_086,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),2882,85,2978,"0,0285426461",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"30,79","15,51"
"low bq, many samples",UPN2_087,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),9083,214,9327,"0,0229441407",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"30,79","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_095,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4648,70,4722,"0,014824227",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"32,29","17,59"
"low bq, low freq, many artifacts, many samples",UPN2_099,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),3044,52,3102,"0,0167633785",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"31,89","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_103,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),4127,53,4187,"0,0126582278",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"32,53","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_107,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),7350,85,7448,"0,0114124597",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"32,32","15,71"
"low bq, low freq, many artifacts, many samples",UPN2_108,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5375,85,5472,"0,0155336257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"32,61","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_110,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5278,60,5345,"0,0112254443",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"32,65","14,73"
"low bq, low freq, many artifacts",UPN2_111,7,148543688,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|agT/agA|p.Ser40Arg/c.120T>A|751|EZH2|protein_coding|CODING|ENST00000320356|3|T),5856,78,5947,"0,0131158567",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,266,Tolerated,"32,31","15,59"
"low bq, low freq, many artifacts, many samples",UPN2_001,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1948,22,1972,"0,0111561866",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"32,15","15,41"
"low bq, low freq, many artifacts, many samples",UPN2_016,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4226,56,4297,"0,0130323481",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"29,97","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_017,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3035,35,3083,"0,0113525787",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"30,28",14
"low bq, low freq, many artifacts, many samples",UPN2_018,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4385,55,4458,"0,012337371",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"30,21","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_020,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4286,80,4383,"0,0182523386",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"28,99","14,09"
"low bq, low freq, many artifacts, many samples",UPN2_021,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4953,83,5057,"0,016412893",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"29,17","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_002,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4736,77,4826,"0,0159552424",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"30,24","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_022,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3985,72,4069,"0,0176947653",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"29,8","14,18"
"low bq, low freq, many artifacts, many samples",UPN2_024,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2770,34,2817,"0,0120695776",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"30,17","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_025,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7142,106,7266,"0,0145884944",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"30,51","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_026,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8681,152,8857,"0,0171615671",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"29,56","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_027,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8584,105,8709,"0,0120564933",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"30,53","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_089,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4087,45,4147,"0,0108512177",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"30,8","14,44"
"low bq, many samples",UPN2_042,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),833,26,863,"0,0301274623",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,29,"15,35"
"low bq, low freq, many artifacts, many samples",UPN2_028,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),6242,105,6363,"0,0165016502",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"30,63","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_029,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4733,50,4792,"0,0104340568",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"32,11","15,28"
"low bq, many samples",UPN2_005,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1115,27,1144,"0,0236013986",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"29,77",14
"low bq, many samples",UPN2_045,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3398,109,3530,"0,030878187",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"28,12","14,43"
"low bq, many samples",UPN2_046,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3877,105,4003,"0,0262303273",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"28,42","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_033,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4836,68,4914,"0,0138380138",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"30,29","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_034,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1994,26,2028,"0,0128205128",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"30,71","14,85"
"low bq, many samples",UPN2_047,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),891,21,916,"0,0229257642",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"28,19",14
"low bq, many samples",UPN2_006,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1794,42,1844,"0,0227765727",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"29,69","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_037,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8017,103,8143,"0,0126489009",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"30,27","14,45"
"low bq, many samples",UPN2_051,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3577,107,3708,"0,0288565264",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"28,15","14,21"
"low bq, many samples",UPN2_052,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7331,209,7570,"0,0276089828",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"28,29","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_038,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10212,140,10375,"0,0134939759",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"30,42","14,55"
"low bq, many samples",UPN2_053,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10060,308,10416,"0,0295698925",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"28,28","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_007,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),6870,101,6984,"0,0144616266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"31,64","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_008,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10092,135,10257,"0,0131617432",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"31,88","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_009,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),10826,222,11088,"0,020021645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"30,2","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_010,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5469,86,5576,"0,0154232425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"31,94","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_011,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4496,71,4576,"0,0155157343",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"31,81","14,49"
"low bq, many samples",UPN2_055,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3395,96,3509,"0,0273582217",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"28,35","14,9"
"low bq, many samples",UPN2_090,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2536,58,2611,"0,0222137112",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"28,67","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_012,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2774,53,2844,"0,0186357243",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"29,73","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_040,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5455,70,5538,"0,0126399422",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"30,26","14,54"
"low bq, many samples",UPN2_013,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2286,57,2349,"0,024265645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"30,29","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_091,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3461,50,3531,"0,0141602945",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"28,33","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_092,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2161,31,2201,"0,014084507",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"29,28",14
"low bq, many samples",UPN2_062,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2154,50,2224,"0,0224820144",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"28,2",14
"low bq, many samples",UPN2_065,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),840,21,864,"0,0243055556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"27,96","14,33"
"low bq, many samples",UPN2_066,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),6128,153,6325,"0,0241897233",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"28,31","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_068,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1060,23,1086,"0,0211786372",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"30,18","14,3"
"low bq, many samples",UPN2_069,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1334,32,1373,"0,0233066278",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"30,72","14,41"
"low bq, many samples",UPN2_071,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1723,55,1790,"0,030726257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"27,82","14,33"
"low bq, many samples",UPN2_073,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),783,22,809,"0,0271940667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"28,54","15,32"
"low bq, many samples",UPN2_074,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5339,145,5526,"0,0262395946",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"27,96","14,27"
"low bq, many samples",UPN2_075,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3275,82,3382,"0,0242460083",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"28,09","14,16"
"low bq, many samples",UPN2_076,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3452,98,3583,"0,0273513815",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"28,19","14,2"
"low bq, many samples",UPN2_077,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),8093,220,8356,"0,0263283868",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"28,06","14,49"
"low bq, many samples",UPN2_080,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1432,34,1473,"0,0230821453",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"28,11","14,53"
"low bq, many samples",UPN2_083,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4970,121,5113,"0,0236651672",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"28,33","14,84"
"low bq, many samples",UPN2_084,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),9023,240,9325,"0,0257372654",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"28,24","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_086,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2896,65,2983,"0,0217901442",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,28,14
"low bq, many samples",UPN2_087,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),9000,254,9334,"0,027212342",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"28,1","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_095,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4610,99,4725,"0,020952381",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"29,28","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_097,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),2129,30,2161,"0,0138824618",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"29,99","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_099,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),3035,57,3104,"0,0183634021",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"28,36","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_101,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4264,73,4352,"0,0167738971",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"29,79","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_103,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4119,57,4189,"0,0136070661",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"29,5","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_104,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),4703,76,4799,"0,0158366326",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"29,37","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_106,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),1359,24,1390,"0,0172661871",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"28,63",14
"low bq, low freq, many artifacts, many samples",UPN2_107,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),7299,115,7450,"0,0154362416",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"29,25","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_108,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5357,88,5474,"0,0160759956",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"29,38","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_109,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5150,55,5228,"0,0105202754",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"31,28","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_110,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5247,78,5347,"0,0145876192",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"29,47","14,18"
"low bq, low freq, many artifacts",UPN2_111,7,148543689,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser40Ile/c.119G>T|751|EZH2|protein_coding|CODING|ENST00000320356|3|A),5836,91,5949,"0,0152966885",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,169,Tolerated,"29,29",14
"low bq, low freq, many artifacts",UPN2_052,7,148544274,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys39Asn/c.117G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),4550,49,4605,"0,010640608",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,6,Damaging,"31,41",14
inspected,UPN2_058,7,148544274,C,G,missense_variant+splice_region_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys39Asn/c.117G>C|751|EZH2|protein_coding|CODING|ENST00000320356|2|G),5078,269,5404,"0,0497779423",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,"0,006",Damaging,"31,48","33,44"
"low bq, low freq, many artifacts, many samples",UPN2_070,7,148544285,C,A,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp36Tyr/c.106G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),4552,49,4608,"0,0106336806",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,55",Deleterious,2,Damaging,"32,75","15,76"
"low bq, low freq, many artifacts, many samples",UPN2_075,7,148544285,C,A,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp36Tyr/c.106G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),4190,46,4241,"0,0108464985",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,55",Deleterious,2,Damaging,"32,48","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_076,7,148544285,C,A,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp36Tyr/c.106G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),5452,56,5516,"0,0101522843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,55",Deleterious,2,Damaging,"32,87","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_087,7,148544299,C,A,missense_variant(MODERATE|MISSENSE|aGg/aTg|p.Arg31Met/c.92G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),3164,39,3209,"0,0121533188",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,9",Deleterious,2,Damaging,"31,88","15,92"
"low bq, low freq, many artifacts, many samples",UPN2_045,7,148544309,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln28Lys/c.82C>A|751|EZH2|protein_coding|CODING|ENST00000320356|2|T),1865,21,1888,"0,0111228814",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,9,Damaging,"31,88",14
"low bq, low freq, many artifacts, many samples",UPN2_050,7,148544309,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln28Lys/c.82C>A|751|EZH2|protein_coding|CODING|ENST00000320356|2|T),2350,33,2407,"0,0137100125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,9,Damaging,"32,04","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_054,7,148544309,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln28Lys/c.82C>A|751|EZH2|protein_coding|CODING|ENST00000320356|2|T),5817,63,5897,"0,0106833983",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,9,Damaging,"31,91","14,11"
"low bq, low freq, many artifacts, many samples",UPN2_058,7,148544309,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln28Lys/c.82C>A|751|EZH2|protein_coding|CODING|ENST00000320356|2|T),10480,123,10620,"0,0115819209",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,9,Damaging,"32,07","18,98"
"low bq, low freq, many artifacts, many samples",UPN2_060,7,148544309,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln28Lys/c.82C>A|751|EZH2|protein_coding|CODING|ENST00000320356|2|T),1648,23,1677,"0,0137149672",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,9,Damaging,"30,47","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_092,7,148544309,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln28Lys/c.82C>A|751|EZH2|protein_coding|CODING|ENST00000320356|2|T),6347,65,6427,"0,0101135833",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,9,Damaging,"32,04","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_061,7,148544309,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln28Lys/c.82C>A|751|EZH2|protein_coding|CODING|ENST00000320356|2|T),10873,133,11029,"0,0120591169",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,9,Damaging,"30,69","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_062,7,148544309,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln28Lys/c.82C>A|751|EZH2|protein_coding|CODING|ENST00000320356|2|T),6834,83,6949,"0,0119441646",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,9,Damaging,"30,77","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_063,7,148544309,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln28Lys/c.82C>A|751|EZH2|protein_coding|CODING|ENST00000320356|2|T),3858,47,3912,"0,0120143149",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,9,Damaging,"30,67","15,64"
"low bq, low freq, many artifacts, many samples",UPN2_066,7,148544309,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln28Lys/c.82C>A|751|EZH2|protein_coding|CODING|ENST00000320356|2|T),9119,96,9243,"0,0103862382",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,9,Damaging,"30,6","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_067,7,148544309,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln28Lys/c.82C>A|751|EZH2|protein_coding|CODING|ENST00000320356|2|T),24078,321,24455,"0,0131261501",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,9,Damaging,"30,56","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_069,7,148544309,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln28Lys/c.82C>A|751|EZH2|protein_coding|CODING|ENST00000320356|2|T),16427,210,16678,"0,0125914378",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,9,Damaging,"30,48","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_070,7,148544309,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln28Lys/c.82C>A|751|EZH2|protein_coding|CODING|ENST00000320356|2|T),8924,105,9048,"0,0116047745",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,9,Damaging,"30,59","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_071,7,148544309,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln28Lys/c.82C>A|751|EZH2|protein_coding|CODING|ENST00000320356|2|T),2620,31,2661,"0,0116497557",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,9,Damaging,"30,46",15
"low bq, low freq, many artifacts, many samples",UPN2_074,7,148544309,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln28Lys/c.82C>A|751|EZH2|protein_coding|CODING|ENST00000320356|2|T),2429,25,2460,"0,0101626016",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,9,Damaging,"30,41","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_075,7,148544309,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln28Lys/c.82C>A|751|EZH2|protein_coding|CODING|ENST00000320356|2|T),8220,108,8347,"0,0129387804",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,9,Damaging,"30,5","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_076,7,148544309,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln28Lys/c.82C>A|751|EZH2|protein_coding|CODING|ENST00000320356|2|T),10701,132,10857,"0,0121580547",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,9,Damaging,"30,61","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_077,7,148544309,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln28Lys/c.82C>A|751|EZH2|protein_coding|CODING|ENST00000320356|2|T),14127,148,14302,"0,010348203",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,9,Damaging,"30,67","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_078,7,148544309,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln28Lys/c.82C>A|751|EZH2|protein_coding|CODING|ENST00000320356|2|T),7993,91,8104,"0,0112290227",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,9,Damaging,"30,66","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_082,7,148544309,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln28Lys/c.82C>A|751|EZH2|protein_coding|CODING|ENST00000320356|2|T),2298,27,2330,"0,0115879828",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,9,Damaging,"30,43","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_083,7,148544309,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln28Lys/c.82C>A|751|EZH2|protein_coding|CODING|ENST00000320356|2|T),15618,172,15829,"0,0108661318",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,9,Damaging,"30,62","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_084,7,148544309,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln28Lys/c.82C>A|751|EZH2|protein_coding|CODING|ENST00000320356|2|T),14034,152,14219,"0,0106899219",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,9,Damaging,"30,55","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_085,7,148544309,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln28Lys/c.82C>A|751|EZH2|protein_coding|CODING|ENST00000320356|2|T),19488,224,19766,"0,0113325913",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,9,Damaging,"30,51","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_086,7,148544309,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln28Lys/c.82C>A|751|EZH2|protein_coding|CODING|ENST00000320356|2|T),16347,167,16565,"0,0100814971",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,9,Damaging,"30,55","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_087,7,148544309,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln28Lys/c.82C>A|751|EZH2|protein_coding|CODING|ENST00000320356|2|T),6259,72,6337,"0,0113618431",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,9,Damaging,"30,61","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_096,7,148544309,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln28Lys/c.82C>A|751|EZH2|protein_coding|CODING|ENST00000320356|2|T),11873,122,12019,"0,0101505949",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,9,Damaging,"32,01","16,26"
"low bq, low freq, many artifacts, many samples",UPN2_097,7,148544309,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln28Lys/c.82C>A|751|EZH2|protein_coding|CODING|ENST00000320356|2|T),9850,115,9986,"0,0115161226",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,9,Damaging,"31,94","15,38"
"low bq, low freq, many artifacts",UPN2_098,7,148544309,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln28Lys/c.82C>A|751|EZH2|protein_coding|CODING|ENST00000320356|2|T),2218,24,2246,"0,0106856634",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,9,Damaging,"32,04",14
"low bq, low freq, many artifacts, many samples",UPN2_062,7,148544317,C,A,missense_variant(MODERATE|MISSENSE|cGa/cTa|p.Arg25Leu/c.74G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),6877,83,6969,"0,0119098866",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,2,Damaging,"28,14","15,3"
"low bq, low freq, many artifacts, many samples",UPN2_067,7,148544317,C,A,missense_variant(MODERATE|MISSENSE|cGa/cTa|p.Arg25Leu/c.74G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),24199,276,24556,"0,0112396156",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,2,Damaging,"27,85","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_068,7,148544317,C,A,missense_variant(MODERATE|MISSENSE|cGa/cTa|p.Arg25Leu/c.74G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),17785,209,18049,"0,0115795889",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,2,Damaging,"27,97","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_069,7,148544317,C,A,missense_variant(MODERATE|MISSENSE|cGa/cTa|p.Arg25Leu/c.74G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),16512,181,16732,"0,010817595",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,2,Damaging,"27,8","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_075,7,148544317,C,A,missense_variant(MODERATE|MISSENSE|cGa/cTa|p.Arg25Leu/c.74G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),8252,108,8380,"0,0128878282",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,2,Damaging,"27,7","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_082,7,148544317,C,A,missense_variant(MODERATE|MISSENSE|cGa/cTa|p.Arg25Leu/c.74G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),2303,28,2337,"0,0119811724",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,2,Damaging,"27,78","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_084,7,148544317,C,A,missense_variant(MODERATE|MISSENSE|cGa/cTa|p.Arg25Leu/c.74G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),14054,157,14269,"0,0110028734",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,2,Damaging,"27,97","15,31"
"low bq, low freq, many artifacts, many samples",UPN2_085,7,148544317,C,A,missense_variant(MODERATE|MISSENSE|cGa/cTa|p.Arg25Leu/c.74G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),19521,235,19821,"0,0118561122",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,2,Damaging,"27,85","15,4"
"low bq, low freq, many artifacts, many samples",UPN2_086,7,148544317,C,A,missense_variant(MODERATE|MISSENSE|cGa/cTa|p.Arg25Leu/c.74G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),16359,186,16632,"0,0111832612",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,2,Damaging,"27,94","15,56"
"low bq, low freq, many artifacts, many samples",UPN2_087,7,148544317,C,A,missense_variant(MODERATE|MISSENSE|cGa/cTa|p.Arg25Leu/c.74G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),6254,72,6353,"0,0113332284",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,2,Damaging,"28,03","16,01"
"low bq, low freq, many artifacts",UPN2_088,7,148544317,C,A,missense_variant(MODERATE|MISSENSE|cGa/cTa|p.Arg25Leu/c.74G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),10751,114,10892,"0,0104663974",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,2,Damaging,"27,77","15,11"
"low freq, many artifacts",UPN2_045,7,148544321,T,C,missense_variant(MODERATE|MISSENSE|Atg/Gtg|p.Met24Val/c.70A>G|751|EZH2|protein_coding|CODING|ENST00000320356|2|C),1867,20,1894,"0,0105596621",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,"0,014",Damaging,"33,12","29,25"
"inspected, not in 2nd illumina, not in 454",UPN2_006,7,148544336,C,T,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val19Ile/c.55G>A|751|EZH2|protein_coding|CODING|ENST00000320356|2|T),275,40,316,"0,1265822785",1,1,0,1,1,1,0,1,6,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,"0,056",Tolerated,"32,62","34,72"
"low bq, low freq, many artifacts",UPN2_045,7,148544339,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg18Ser/c.52C>A|751|EZH2|protein_coding|CODING|ENST00000320356|2|T),1853,31,1894,"0,0163674762",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,68",Deleterious,44,Damaging,"30,7","22,45"
"low bq, low freq, many artifacts, many samples",UPN2_060,7,148544344,C,A,missense_variant(MODERATE|MISSENSE|cGg/cTg|p.Arg16Leu/c.47G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),1653,20,1676,"0,0119331742",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,2,Damaging,"27,35","17,1"
"low bq, low freq, many artifacts, many samples",UPN2_062,7,148544344,C,A,missense_variant(MODERATE|MISSENSE|cGg/cTg|p.Arg16Leu/c.47G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),6856,102,6978,"0,0146173689",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,2,Damaging,"27,52","22,48"
"low bq, low freq, many artifacts, many samples",UPN2_067,7,148544344,C,A,missense_variant(MODERATE|MISSENSE|cGg/cTg|p.Arg16Leu/c.47G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),24225,252,24541,"0,0102685302",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,2,Damaging,"27,3","15,39"
"low bq, low freq, many artifacts, many samples",UPN2_068,7,148544344,C,A,missense_variant(MODERATE|MISSENSE|cGg/cTg|p.Arg16Leu/c.47G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),17833,184,18050,"0,0101939058",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,2,Damaging,"27,4","16,18"
"low bq, low freq, many artifacts, many samples",UPN2_069,7,148544344,C,A,missense_variant(MODERATE|MISSENSE|cGg/cTg|p.Arg16Leu/c.47G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),16489,191,16721,"0,0114227618",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,2,Damaging,"27,38",16
"low bq, low freq, many artifacts, many samples",UPN2_074,7,148544344,C,A,missense_variant(MODERATE|MISSENSE|cGg/cTg|p.Arg16Leu/c.47G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),2436,29,2468,"0,0117504052",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,2,Damaging,"27,24","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_076,7,148544344,C,A,missense_variant(MODERATE|MISSENSE|cGg/cTg|p.Arg16Leu/c.47G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),10765,115,10901,"0,0105494909",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,2,Damaging,"27,57","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_082,7,148544344,C,A,missense_variant(MODERATE|MISSENSE|cGg/cTg|p.Arg16Leu/c.47G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),2295,28,2333,"0,0120017145",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,2,Damaging,"27,55","18,61"
"low bq, low freq, many artifacts, many samples",UPN2_083,7,148544344,C,A,missense_variant(MODERATE|MISSENSE|cGg/cTg|p.Arg16Leu/c.47G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),15683,163,15900,"0,0102515723",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,2,Damaging,"27,48","16,27"
"low bq, low freq, many artifacts",UPN2_088,7,148544344,C,A,missense_variant(MODERATE|MISSENSE|cGg/cTg|p.Arg16Leu/c.47G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),10761,111,10907,"0,0101769506",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,2,Damaging,"27,33","16,27"
"low bq, low freq, many artifacts, many samples",UPN2_014,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),13661,141,13818,"0,0102040816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,29,"14,33"
"low bq, low freq, many artifacts, many samples",UPN2_016,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),9866,114,9996,"0,0114045618",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,9","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_018,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),10150,105,10278,"0,0102159953",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"29,2","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_020,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),8486,90,8590,"0,0104772992",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"29,24","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_023,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),14862,159,15062,"0,010556367",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"29,08","14,04"
"low bq, low freq, many artifacts, many samples",UPN2_025,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),16510,168,16693,"0,0100640987",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,98","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_004,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),1807,22,1832,"0,0120087336",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"29,94","15,59"
"low bq, low freq, many artifacts, many samples",UPN2_027,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),19638,201,19868,"0,0101167707",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"29,16","14,26"
"low bq, many samples",UPN2_089,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),13254,309,13582,"0,0227506995",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,94",15
"low bq, low freq, many artifacts, many samples",UPN2_028,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),15760,161,15946,"0,0100965759",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"29,24","14,29"
"low bq, many samples",UPN2_045,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),1827,43,1874,"0,022945571",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,18",14
"low bq, many samples",UPN2_046,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),2020,50,2080,"0,0240384615",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,36","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_034,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),4943,54,5002,"0,0107956817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"29,22","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_035,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),12626,133,12799,"0,0103914368",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"29,02","14,53"
"low bq, many samples",UPN2_050,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),2346,55,2406,"0,0228595179",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,35","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_051,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),7152,115,7288,"0,0157793633",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,26","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_052,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),8848,162,9043,"0,0179144089",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,22","14,99"
"low bq, many samples",UPN2_053,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),10587,254,10869,"0,0233692152",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,16","14,36"
"low bq, many samples",UPN2_054,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),5695,150,5860,"0,0255972696",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,3","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_007,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),28599,334,28986,"0,0115228041",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"29,39","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_008,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),35536,396,35999,"0,0110003056",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"29,59","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_009,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),27986,295,28327,"0,0104140926",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"29,45","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_010,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),21519,223,21787,"0,0102354615",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"29,63","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_055,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),1122,21,1149,"0,0182767624",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"27,93","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_090,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),7639,171,7821,"0,0218642117",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,79","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_057,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),6922,144,7079,"0,0203418562",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,17","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_058,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),10366,217,10607,"0,020458188",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,23","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_012,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),4392,53,4452,"0,0119047619",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"29,23","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_060,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),1629,33,1670,"0,019760479",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,8","15,58"
"low bq, low freq, many artifacts, many samples",UPN2_013,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),6687,81,6793,"0,0119240395",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"29,39","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_091,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),1405,30,1439,"0,020847811",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,69","14,43"
"low bq, many samples",UPN2_092,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),6266,142,6419,"0,0221218258",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,88","14,6"
"low bq, many samples",UPN2_093,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),9367,228,9614,"0,023715415",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,89","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_061,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),10777,227,11049,"0,0205448457",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,61","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_062,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),6788,134,6942,"0,0193027946",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,73","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_063,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),3816,84,3914,"0,0214614205",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,54","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_066,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),9035,194,9275,"0,020916442",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,64","14,94"
"low bq, many samples",UPN2_067,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),23762,543,24404,"0,0222504507",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,53","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_068,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),17546,356,17970,"0,0198107958",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,73","14,65"
"low bq, many samples",UPN2_069,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),16158,375,16601,"0,0225890007",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,57","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_070,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),8839,159,9038,"0,0175923877",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,6","14,99"
"low bq, many samples",UPN2_071,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),2569,65,2647,"0,0245561012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,9","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_074,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),2398,41,2447,"0,0167552105",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,62","14,49"
"low bq, many samples",UPN2_075,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),8100,205,8327,"0,0246187102",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,49","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_076,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),10569,229,10847,"0,0211118282",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,71","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_077,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),13961,275,14286,"0,019249615",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,64","15,6"
"low bq, low freq, many artifacts, many samples",UPN2_078,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),7903,173,8116,"0,0213159192",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,63","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_079,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),3017,58,3090,"0,0187702265",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,47","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_082,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),2276,43,2324,"0,0185025818",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,37","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_083,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),15446,324,15830,"0,0204674668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,73","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_084,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),13853,276,14198,"0,0194393577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,71","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_085,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),19204,420,19720,"0,0212981744",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,6","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_086,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),16130,364,16558,"0,0219833313",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,63","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_087,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),6122,137,6294,"0,021766762",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,83","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_088,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),10576,230,10849,"0,0212001106",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,52","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_094,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),9721,212,9953,"0,0213001105",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,9","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_095,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),12566,260,12871,"0,0202004506",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,91","14,68"
"low bq, many samples",UPN2_096,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),11701,278,12016,"0,0231358189",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"29,02","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_097,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),9722,208,9957,"0,0208898263",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,84","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_098,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),2191,49,2256,"0,0217198582",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,9","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_099,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),6627,135,6770,"0,0199409158",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,92","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_100,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),9094,197,9307,"0,0211668637",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,29,"14,92"
"low bq, low freq, many artifacts, many samples",UPN2_101,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),12816,253,13106,"0,0193041355",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,92","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_102,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),13164,286,13475,"0,0212244898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,89","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_103,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),12187,256,12466,"0,0205358575",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"29,01","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_104,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),13609,282,13922,"0,0202557104",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,29,"14,89"
"low bq, low freq, many artifacts, many samples",UPN2_105,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),6701,137,6853,"0,0199912447",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,95","15,14"
"low bq, many samples",UPN2_107,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),18755,429,19239,"0,0222984563",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,93","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_108,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),14221,282,14523,"0,0194174757",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,79","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_109,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),16857,368,17254,"0,0213283876",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,91","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_110,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),14229,304,14562,"0,0208762533",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,79","14,7"
"low bq, low freq, many artifacts",UPN2_111,7,148544350,C,A,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys14Phe/c.41G>T|751|EZH2|protein_coding|CODING|ENST00000320356|2|A),17137,339,17518,"0,0193515241",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,"0,07",Tolerated,"28,83","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_051,7,148544351,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys14Ser/c.40T>A|751|EZH2|protein_coding|CODING|ENST00000320356|2|T),3723,50,3787,"0,0132030631",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,628,Tolerated,"33,24","20,14"
"low bq, low freq, many artifacts, many samples",UPN2_052,7,148544351,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys14Ser/c.40T>A|751|EZH2|protein_coding|CODING|ENST00000320356|2|T),4582,50,4655,"0,0107411386",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,628,Tolerated,"33,07","17,18"
"low bq, low freq, many artifacts, many samples",UPN2_054,7,148544351,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys14Ser/c.40T>A|751|EZH2|protein_coding|CODING|ENST00000320356|2|T),2991,31,3036,"0,0102108037",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,628,Tolerated,"33,18","17,94"
"low bq, low freq, many artifacts",UPN2_058,7,148544351,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys14Ser/c.40T>A|751|EZH2|protein_coding|CODING|ENST00000320356|2|T),5383,62,5481,"0,0113118044",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,3",Neutral,628,Tolerated,"33,34","17,24"
"low bq, low freq, many artifacts, many samples",UPN2_051,7,148544353,A,T,missense_variant(MODERATE|MISSENSE|gTt/gAt|p.Val13Asp/c.38T>A|751|EZH2|protein_coding|CODING|ENST00000320356|2|T),3577,50,3649,"0,0137023842",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,32",Neutral,"0,01",Damaging,"32,45","18,74"
"low bq, low freq, many artifacts, many samples",UPN2_052,7,148544353,A,T,missense_variant(MODERATE|MISSENSE|gTt/gAt|p.Val13Asp/c.38T>A|751|EZH2|protein_coding|CODING|ENST00000320356|2|T),4433,60,4524,"0,0132625995",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,32",Neutral,"0,01",Damaging,"32,43","16,87"
"low bq, low freq, many artifacts, many samples",UPN2_053,7,148544353,A,T,missense_variant(MODERATE|MISSENSE|gTt/gAt|p.Val13Asp/c.38T>A|751|EZH2|protein_coding|CODING|ENST00000320356|2|T),5335,65,5421,"0,0119904077",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,32",Neutral,"0,01",Damaging,"32,36","17,68"
"low bq, low freq, many artifacts, many samples",UPN2_057,7,148544353,A,T,missense_variant(MODERATE|MISSENSE|gTt/gAt|p.Val13Asp/c.38T>A|751|EZH2|protein_coding|CODING|ENST00000320356|2|T),3491,39,3542,"0,0110107284",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,32",Neutral,"0,01",Damaging,"32,25","14,46"
"low bq, low freq, many artifacts",UPN2_058,7,148544353,A,T,missense_variant(MODERATE|MISSENSE|gTt/gAt|p.Val13Asp/c.38T>A|751|EZH2|protein_coding|CODING|ENST00000320356|2|T),5191,57,5291,"0,0107730108",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,32",Neutral,"0,01",Damaging,"32,45","16,23"
"low bq, low freq, many artifacts",UPN2_087,7,148544356,G,T,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro12Gln/c.35C>A|751|EZH2|protein_coding|CODING|ENST00000320356|2|T),3120,33,3167,"0,0104199558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,-2,Neutral,6,Damaging,"32,33",14
"low bq, low freq, many artifacts, many samples",UPN2_001,9,5069973,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro521Gln/c.1562C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),1889,23,1913,"0,0120230005",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,163,Tolerated,"29,91","15,52"
"low bq, low freq, many artifacts, many samples",UPN2_002,9,5069973,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro521Gln/c.1562C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),2412,28,2440,"0,0114754098",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,163,Tolerated,"29,69","16,04"
"low bq, low freq, many artifacts, many samples",UPN2_046,9,5069973,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro521Gln/c.1562C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),1993,31,2028,"0,0152859961",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,163,Tolerated,"30,04","18,97"
"low bq, low freq, many artifacts, many samples",UPN2_051,9,5069973,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro521Gln/c.1562C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),3302,54,3361,"0,0160666468",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,163,Tolerated,"29,67","17,43"
"low bq, low freq, many artifacts, many samples",UPN2_053,9,5069973,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro521Gln/c.1562C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),3793,58,3857,"0,015037594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,163,Tolerated,"29,82","16,81"
"low bq, low freq, many artifacts, many samples",UPN2_054,9,5069973,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro521Gln/c.1562C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),2558,30,2594,"0,0115651503",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,163,Tolerated,"29,86","19,87"
"low bq, low freq, many artifacts, many samples",UPN2_007,9,5069973,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro521Gln/c.1562C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),6409,92,6531,"0,0140866636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,163,Tolerated,"29,59","16,63"
"low bq, low freq, many artifacts, many samples",UPN2_008,9,5069973,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro521Gln/c.1562C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),6799,85,6890,"0,0123367199",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,163,Tolerated,"29,51","16,48"
"low bq, low freq, many artifacts, many samples",UPN2_009,9,5069973,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro521Gln/c.1562C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),5896,71,5971,"0,0118908056",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,163,Tolerated,"29,48","15,34"
"low bq, low freq, many artifacts, many samples",UPN2_010,9,5069973,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro521Gln/c.1562C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),5818,86,5913,"0,0145442246",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,163,Tolerated,"29,5","16,56"
"low bq, low freq, many artifacts, many samples",UPN2_011,9,5069973,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro521Gln/c.1562C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),5725,67,5802,"0,0115477422",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,163,Tolerated,"29,43","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_055,9,5069973,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro521Gln/c.1562C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),2119,31,2160,"0,0143518519",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,163,Tolerated,"29,66","15,42"
"low bq, low freq, many artifacts, many samples",UPN2_057,9,5069973,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro521Gln/c.1562C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),2420,38,2462,"0,015434606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,163,Tolerated,"30,07","18,63"
"low bq, low freq, many artifacts, many samples",UPN2_058,9,5069973,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro521Gln/c.1562C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),4505,58,4574,"0,0126803673",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,163,Tolerated,"29,97","17,66"
"low bq, low freq, many artifacts, many samples",UPN2_012,9,5069973,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro521Gln/c.1562C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),2248,28,2280,"0,0122807018",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,163,Tolerated,"29,69","16,36"
"low bq, low freq, many artifacts, many samples",UPN2_060,9,5069973,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro521Gln/c.1562C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),4480,69,4557,"0,0151415405",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,163,Tolerated,"28,42",17
"low bq, low freq, many artifacts, many samples",UPN2_013,9,5069973,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro521Gln/c.1562C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),1805,23,1829,"0,0125751777",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,163,Tolerated,"29,68","17,61"
"low bq, low freq, many artifacts, many samples",UPN2_061,9,5069973,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro521Gln/c.1562C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),5464,89,5561,"0,0160043158",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,163,Tolerated,"28,52","16,06"
"low bq, low freq, many artifacts, many samples",UPN2_062,9,5069973,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro521Gln/c.1562C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),4350,76,4438,"0,017124831",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,163,Tolerated,"28,51","16,67"
"low bq, low freq, many artifacts, many samples",UPN2_063,9,5069973,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro521Gln/c.1562C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),4022,67,4093,"0,0163694112",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,163,Tolerated,"28,7","17,55"
"low bq, low freq, many artifacts, many samples",UPN2_066,9,5069973,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro521Gln/c.1562C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),11903,209,12129,"0,0172314288",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,163,Tolerated,"28,48","15,49"
"low bq, low freq, many artifacts, many samples",UPN2_067,9,5069973,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro521Gln/c.1562C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),16202,279,16505,"0,0169039685",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,163,Tolerated,"28,5","16,63"
"low bq, low freq, many artifacts, many samples",UPN2_068,9,5069973,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro521Gln/c.1562C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),9836,163,10022,"0,0162642187",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,163,Tolerated,"28,5","16,62"
"low bq, low freq, many artifacts, many samples",UPN2_069,9,5069973,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro521Gln/c.1562C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),8683,141,8837,"0,0159556411",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,163,Tolerated,"28,49","16,25"
"low bq, low freq, many artifacts, many samples",UPN2_070,9,5069973,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro521Gln/c.1562C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),5526,87,5618,"0,0154859381",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,163,Tolerated,"28,44","16,54"
"low bq, low freq, many artifacts, many samples",UPN2_071,9,5069973,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro521Gln/c.1562C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),3890,62,3962,"0,0156486623",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,163,Tolerated,"28,3","16,35"
"low bq, low freq, many artifacts, many samples",UPN2_072,9,5069973,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro521Gln/c.1562C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),1461,32,1496,"0,0213903743",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,163,Tolerated,"28,22","15,81"
"low bq, low freq, many artifacts, many samples",UPN2_074,9,5069973,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro521Gln/c.1562C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),4438,77,4525,"0,0170165746",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,163,Tolerated,"28,42","16,49"
"low bq, low freq, many artifacts, many samples",UPN2_075,9,5069973,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro521Gln/c.1562C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),6965,106,7084,"0,0149632976",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,163,Tolerated,"28,29","17,69"
"low bq, low freq, many artifacts, many samples",UPN2_076,9,5069973,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro521Gln/c.1562C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),7594,118,7721,"0,0152829944",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,163,Tolerated,"28,51","15,34"
"low bq, low freq, many artifacts, many samples",UPN2_077,9,5069973,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro521Gln/c.1562C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),9927,168,10123,"0,0165958708",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,163,Tolerated,"28,46","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_078,9,5069973,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro521Gln/c.1562C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),7108,102,7226,"0,0141156933",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,163,Tolerated,"28,63","16,17"
"low bq, low freq, many artifacts, many samples",UPN2_079,9,5069973,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro521Gln/c.1562C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),4577,84,4667,"0,0179987144",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,163,Tolerated,"28,26","17,77"
"low bq, low freq, many artifacts, many samples",UPN2_080,9,5069973,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro521Gln/c.1562C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),2942,64,3010,"0,0212624585",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,163,Tolerated,"28,24","17,92"
"low bq, low freq, many artifacts, many samples",UPN2_082,9,5069973,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro521Gln/c.1562C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),8133,127,8278,"0,01534187",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,163,Tolerated,"28,33","16,57"
"low bq, low freq, many artifacts, many samples",UPN2_083,9,5069973,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro521Gln/c.1562C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),9532,137,9701,"0,0141222554",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,163,Tolerated,"28,68","16,75"
"low bq, low freq, many artifacts, many samples",UPN2_084,9,5069973,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro521Gln/c.1562C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),11096,162,11284,"0,0143566111",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,163,Tolerated,"28,68","16,09"
"low bq, low freq, many artifacts, many samples",UPN2_085,9,5069973,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro521Gln/c.1562C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),17906,346,18295,"0,0189122711",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,163,Tolerated,"28,46","17,27"
"low bq, low freq, many artifacts, many samples",UPN2_086,9,5069973,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro521Gln/c.1562C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),16338,287,16652,"0,0172351669",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,163,Tolerated,"28,59","17,29"
"low bq, low freq, many artifacts, many samples",UPN2_087,9,5069973,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro521Gln/c.1562C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),9632,138,9787,"0,0141003372",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,163,Tolerated,"28,44","16,14"
"low bq, low freq, many artifacts",UPN2_088,9,5069973,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro521Gln/c.1562C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),7913,141,8068,"0,0174764502",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,163,Tolerated,"28,52","16,43"
"low bq, low freq, many artifacts, many samples",UPN2_001,9,5069982,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro524Gln/c.1571C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),1887,22,1913,"0,0115002614",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,24,Damaging,"29,14",15
"low bq, low freq, many artifacts, many samples",UPN2_045,9,5069982,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro524Gln/c.1571C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),1056,20,1078,"0,0185528757",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,24,Damaging,"28,41",14
"low bq, low freq, many artifacts, many samples",UPN2_046,9,5069982,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro524Gln/c.1571C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),2003,22,2028,"0,0108481262",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,24,Damaging,"28,79","18,59"
"low bq, low freq, many artifacts, many samples",UPN2_051,9,5069982,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro524Gln/c.1571C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),3309,47,3361,"0,0139839334",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,24,Damaging,"28,62","18,77"
"low bq, low freq, many artifacts, many samples",UPN2_052,9,5069982,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro524Gln/c.1571C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),1771,20,1798,"0,0111234705",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,24,Damaging,"28,2","15,75"
"low bq, low freq, many artifacts, many samples",UPN2_053,9,5069982,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro524Gln/c.1571C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),3797,54,3857,"0,0140005185",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,24,Damaging,"28,48","17,09"
"low bq, low freq, many artifacts, many samples",UPN2_007,9,5069982,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro524Gln/c.1571C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),6427,95,6530,"0,0145482389",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,24,Damaging,"28,83","16,55"
"low bq, low freq, many artifacts, many samples",UPN2_008,9,5069982,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro524Gln/c.1571C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),6805,78,6890,"0,0113207547",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,24,Damaging,"28,88","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_009,9,5069982,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro524Gln/c.1571C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),5901,64,5972,"0,0107166778",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,24,Damaging,"28,84","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_010,9,5069982,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro524Gln/c.1571C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),5827,79,5912,"0,0133626522",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,24,Damaging,"28,82","16,28"
"low bq, low freq, many artifacts, many samples",UPN2_011,9,5069982,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro524Gln/c.1571C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),5736,60,5800,"0,0103448276",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,24,Damaging,"28,61","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_055,9,5069982,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro524Gln/c.1571C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),2123,34,2160,"0,0157407407",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,24,Damaging,"28,39","17,35"
"low bq, low freq, many artifacts, many samples",UPN2_057,9,5069982,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro524Gln/c.1571C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),2407,32,2462,"0,012997563",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,24,Damaging,"28,4","19,5"
"low bq, low freq, many artifacts, many samples",UPN2_058,9,5069982,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro524Gln/c.1571C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),4519,48,4574,"0,0104940971",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,24,Damaging,"28,6","18,69"
"low bq, low freq, many artifacts, many samples",UPN2_012,9,5069982,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro524Gln/c.1571C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),2243,33,2280,"0,0144736842",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,24,Damaging,"29,03","15,73"
"low bq, low freq, many artifacts, many samples",UPN2_060,9,5069982,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro524Gln/c.1571C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),4492,60,4555,"0,0131723381",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,24,Damaging,"27,88","16,07"
"low bq, low freq, many artifacts, many samples",UPN2_061,9,5069982,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro524Gln/c.1571C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),5494,59,5559,"0,0106134197",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,24,Damaging,"27,81","15,93"
"low bq, low freq, many artifacts, many samples",UPN2_062,9,5069982,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro524Gln/c.1571C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),4374,55,4437,"0,0123957629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,24,Damaging,"27,84","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_063,9,5069982,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro524Gln/c.1571C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),4037,51,4092,"0,0124633431",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,24,Damaging,"27,83","20,29"
"low bq, low freq, many artifacts, many samples",UPN2_066,9,5069982,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro524Gln/c.1571C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),11923,177,12124,"0,0145991422",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,24,Damaging,"27,83","15,4"
"low bq, low freq, many artifacts, many samples",UPN2_067,9,5069982,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro524Gln/c.1571C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),16257,223,16503,"0,0135126947",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,24,Damaging,"27,72","16,1"
"low bq, low freq, many artifacts, many samples",UPN2_068,9,5069982,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro524Gln/c.1571C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),9882,122,10019,"0,012176864",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,24,Damaging,"27,83","16,3"
"low bq, low freq, many artifacts, many samples",UPN2_069,9,5069982,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro524Gln/c.1571C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),8717,112,8837,"0,0126739844",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,24,Damaging,"27,81","16,97"
"low bq, low freq, many artifacts, many samples",UPN2_070,9,5069982,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro524Gln/c.1571C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),5533,80,5618,"0,014239943",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,24,Damaging,"27,76","16,75"
"low bq, low freq, many artifacts, many samples",UPN2_071,9,5069982,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro524Gln/c.1571C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),3895,55,3961,"0,0138853825",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,24,Damaging,"27,84","16,8"
"low bq, low freq, many artifacts, many samples",UPN2_072,9,5069982,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro524Gln/c.1571C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),1470,24,1496,"0,0160427807",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,24,Damaging,"27,57","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_074,9,5069982,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro524Gln/c.1571C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),4451,68,4524,"0,0150309461",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,24,Damaging,"27,72","16,26"
"low bq, low freq, many artifacts, many samples",UPN2_075,9,5069982,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro524Gln/c.1571C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),6973,100,7084,"0,0141163185",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,24,Damaging,"27,7","15,71"
"low bq, low freq, many artifacts, many samples",UPN2_076,9,5069982,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro524Gln/c.1571C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),7596,108,7719,"0,0139914497",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,24,Damaging,"27,82","16,72"
"low bq, low freq, many artifacts, many samples",UPN2_077,9,5069982,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro524Gln/c.1571C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),9947,148,10122,"0,0146216163",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,24,Damaging,"27,79","15,99"
"low bq, low freq, many artifacts, many samples",UPN2_078,9,5069982,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro524Gln/c.1571C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),7131,82,7223,"0,0113526236",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,24,Damaging,"27,85","16,3"
"low bq, low freq, many artifacts, many samples",UPN2_079,9,5069982,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro524Gln/c.1571C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),4595,65,4666,"0,0139305615",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,24,Damaging,"27,72","16,52"
"low bq, low freq, many artifacts, many samples",UPN2_080,9,5069982,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro524Gln/c.1571C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),2960,47,3010,"0,0156146179",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,24,Damaging,"27,79","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_082,9,5069982,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro524Gln/c.1571C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),8155,106,8278,"0,0128050254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,24,Damaging,"27,82","16,51"
"low bq, low freq, many artifacts, many samples",UPN2_083,9,5069982,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro524Gln/c.1571C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),9558,124,9700,"0,0127835052",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,24,Damaging,"28,01","16,6"
"low bq, low freq, many artifacts, many samples",UPN2_084,9,5069982,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro524Gln/c.1571C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),11124,131,11283,"0,0116103873",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,24,Damaging,"27,77","17,6"
"low bq, low freq, many artifacts, many samples",UPN2_085,9,5069982,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro524Gln/c.1571C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),17994,264,18290,"0,014434117",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,24,Damaging,"27,68","15,9"
"low bq, low freq, many artifacts, many samples",UPN2_086,9,5069982,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro524Gln/c.1571C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),16414,198,16647,"0,011894035",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,24,Damaging,"27,8","16,96"
"low bq, low freq, many artifacts, many samples",UPN2_087,9,5069982,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro524Gln/c.1571C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),9641,130,9786,"0,0132842837",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,24,Damaging,"27,63","17,47"
"low bq, low freq, many artifacts, many samples",UPN2_088,9,5069982,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro524Gln/c.1571C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),7944,112,8066,"0,0138854451",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,24,Damaging,"27,64","16,85"
"low bq, low freq, many artifacts",UPN2_105,9,5069982,C,A,missense_variant(MODERATE|MISSENSE|cCa/cAa|p.Pro524Gln/c.1571C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),2492,27,2522,"0,0107057891",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,24,Damaging,"28,61","15,63"
"low bq, low freq, many artifacts, many samples",UPN2_016,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),5010,51,5076,"0,0100472813",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"28,77","20,25"
"low bq, low freq, many artifacts, many samples",UPN2_023,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),8762,90,8885,"0,0101294316",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"28,6","16,22"
"low bq, low freq, many artifacts, many samples",UPN2_024,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),3074,32,3118,"0,0102629891",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"28,63","21,28"
"low bq, low freq, many artifacts, many samples",UPN2_089,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),7515,90,7624,"0,0118048269",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"28,04","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_028,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),7916,84,8028,"0,0104633782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"28,41","18,96"
"low bq, low freq, many artifacts, many samples",UPN2_043,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),2216,30,2253,"0,0133155792",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"28,38","17,17"
"low bq, low freq, many artifacts, many samples",UPN2_045,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),2086,24,2116,"0,011342155",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"28,57","15,96"
"low bq, low freq, many artifacts, many samples",UPN2_046,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),3914,46,3984,"0,0115461847",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"28,53","18,04"
"low bq, low freq, many artifacts, many samples",UPN2_050,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),2767,40,2812,"0,0142247511",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"28,35","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_037,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),10429,109,10590,"0,010292729",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"28,57","16,18"
"low bq, low freq, many artifacts, many samples",UPN2_051,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),6528,72,6624,"0,0108695652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"28,51","17,49"
"low bq, low freq, many artifacts, many samples",UPN2_052,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),3495,44,3561,"0,0123560798",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"28,35","15,48"
"low bq, low freq, many artifacts, many samples",UPN2_053,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),7452,100,7588,"0,0131787032",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"28,41","16,54"
"low bq, low freq, many artifacts, many samples",UPN2_054,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),5014,73,5101,"0,0143109194",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"28,54","17,15"
"low bq, low freq, many artifacts, many samples",UPN2_055,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),4172,49,4242,"0,0115511551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"28,51","17,65"
"low bq, low freq, many artifacts, many samples",UPN2_058,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),8884,94,9016,"0,0104259095",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"28,36","16,1"
"low bq, low freq, many artifacts, many samples",UPN2_060,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),8822,117,8968,"0,0130463872",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"28,5","16,66"
"low bq, low freq, many artifacts, many samples",UPN2_091,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),1837,20,1864,"0,0107296137",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"28,17","17,2"
"low bq, low freq, many artifacts, many samples",UPN2_092,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),2757,39,2802,"0,0139186296",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"27,98","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_061,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),10795,124,10947,"0,0113273043",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"28,57","16,59"
"low bq, low freq, many artifacts, many samples",UPN2_062,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),8571,110,8718,"0,0126175728",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"28,56","16,62"
"low bq, low freq, many artifacts, many samples",UPN2_067,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),31967,360,32437,"0,011098437",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"28,74","16,98"
"low bq, low freq, many artifacts, many samples",UPN2_068,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),19363,283,19718,"0,0143523684",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"28,62","16,95"
"low bq, low freq, many artifacts, many samples",UPN2_069,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),17085,186,17340,"0,0107266436",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"28,63","16,16"
"low bq, low freq, many artifacts, many samples",UPN2_070,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),10864,130,11047,"0,0117679008",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"28,65","16,48"
"low bq, low freq, many artifacts, many samples",UPN2_071,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),7686,101,7799,"0,0129503783",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"28,6","16,53"
"low bq, low freq, many artifacts, many samples",UPN2_072,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),2901,36,2945,"0,0122241087",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"28,72","19,03"
"low bq, low freq, many artifacts, many samples",UPN2_074,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),8744,139,8923,"0,0155777205",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"28,66","16,98"
"low bq, low freq, many artifacts, many samples",UPN2_075,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),13747,164,13951,"0,0117554297",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"28,62","16,82"
"low bq, low freq, many artifacts, many samples",UPN2_076,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),14967,174,15194,"0,0114518889",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"28,69","16,45"
"low bq, low freq, many artifacts, many samples",UPN2_077,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),19624,258,19940,"0,0129388164",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"28,59","16,8"
"low bq, low freq, many artifacts, many samples",UPN2_078,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),13996,179,14223,"0,0125852492",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"28,5","15,91"
"low bq, low freq, many artifacts, many samples",UPN2_079,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),9059,92,9189,"0,0100119708",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"28,63","15,98"
"low bq, low freq, many artifacts, many samples",UPN2_080,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),5833,69,5937,"0,0116220313",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"28,55","16,78"
"low bq, low freq, many artifacts, many samples",UPN2_082,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),16095,167,16314,"0,0102366066",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"28,61","16,8"
"low bq, low freq, many artifacts, many samples",UPN2_083,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),18763,220,19091,"0,0115237546",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"28,53","16,31"
"low bq, low freq, many artifacts, many samples",UPN2_084,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),21880,263,22231,"0,011830327",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"28,66","15,94"
"low bq, low freq, many artifacts, many samples",UPN2_085,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),35461,433,36018,"0,0120217669",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"28,62","17,34"
"low bq, low freq, many artifacts, many samples",UPN2_086,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),32337,344,32804,"0,010486526",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"28,53","16,15"
"low bq, low freq, many artifacts, many samples",UPN2_087,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),19039,220,19305,"0,0113960114",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"28,63","15,98"
"low bq, low freq, many artifacts, many samples",UPN2_088,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),15656,185,15884,"0,0116469403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"28,72","16,31"
"low bq, low freq, many artifacts, many samples",UPN2_094,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),4113,55,4185,"0,0131421744",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"27,89","15,96"
"low bq, low freq, many artifacts, many samples",UPN2_095,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),5365,56,5439,"0,0102960103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"27,96","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_101,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),6153,66,6245,"0,0105684548",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"27,91","15,45"
"low bq, low freq, many artifacts, many samples",UPN2_102,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),6316,95,6438,"0,0147561354",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"28,01","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_103,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),6357,87,6455,"0,0134779241",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"27,8","15,8"
"low bq, low freq, many artifacts, many samples",UPN2_104,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),6852,90,6959,"0,0129328927",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"27,91","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_105,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),4921,59,4997,"0,0118070843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"27,96","16,71"
"low bq, low freq, many artifacts, many samples",UPN2_109,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),8176,96,8302,"0,0115634787",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"27,92","14,46"
"low bq, low freq, many artifacts",UPN2_111,9,5069987,T,A,missense_variant(MODERATE|MISSENSE|Tta/Ata|p.Leu526Ile/c.1576T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),9315,110,9458,"0,0116303658",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,247,Tolerated,"27,98","14,68"
"low bq, low freq, many artifacts",UPN2_058,9,5069994,G,T,missense_variant(MODERATE|MISSENSE|aGg/aTg|p.Arg528Met/c.1583G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|12|T),8908,105,9045,"0,0116086235",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,12",Neutral,25,Damaging,"28,71","18,29"
"low bq, low freq, many artifacts, many samples",UPN2_065,9,5069995,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg528Ser/c.1584G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|12|T),1619,35,1656,"0,0211352657",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,48",Neutral,156,Tolerated,"28,61","21,34"
"low bq, low freq, many artifacts, many samples",UPN2_072,9,5069995,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg528Ser/c.1584G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|12|T),2917,31,2955,"0,0104906937",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,48",Neutral,156,Tolerated,"28,27","16,06"
"low freq, many artifacts",UPN2_065,9,5069996,C,T,missense_variant(MODERATE|MISSENSE|Cct/Tct|p.Pro529Ser/c.1585C>T|1132|JAK2|protein_coding|CODING|ENST00000381652|12|T),1621,20,1656,"0,0120772947",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,2",Neutral,"0,842",Tolerated,"27,5","32,05"
"low freq, many artifacts",UPN2_057,9,5069999,A,T,missense_variant(MODERATE|MISSENSE|Act/Tct|p.Thr530Ser/c.1588A>T|1132|JAK2|protein_coding|CODING|ENST00000381652|12|T),4779,75,4869,"0,0154035736",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,19",Neutral,"0,409",Tolerated,"33,32","28,73"
"low freq, many artifacts",UPN2_046,9,5070006,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met532Thr/c.1595T>C|1132|JAK2|protein_coding|CODING|ENST00000381652|12|C),3947,46,4009,"0,0114741831",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,003",Damaging,"33,12","31,85"
"low bq, low freq, many artifacts, many samples",UPN2_050,9,5070008,A,T,missense_variant(MODERATE|MISSENSE|Aac/Tac|p.Asn533Tyr/c.1597A>T|1132|JAK2|protein_coding|CODING|ENST00000381652|12|T),2773,40,2821,"0,014179369",0,0,0,0,1,0,0,0,1,NO,NO,COSM29471,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-3,2",Deleterious,1,Damaging,"33,31","24,02"
"low bq, low freq, many artifacts, many samples",UPN2_046,9,5070013,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln534His/c.1602A>T|1132|JAK2|protein_coding|CODING|ENST00000381652|12|T),3948,42,4009,"0,010476428",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,62",Deleterious,81,Tolerated,"32,87","23,52"
"low bq, low freq, many artifacts",UPN2_055,9,5070013,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln534His/c.1602A>T|1132|JAK2|protein_coding|CODING|ENST00000381652|12|T),4231,43,4279,"0,0100490769",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,62",Deleterious,81,Tolerated,"32,78","23,47"
"low bq, low freq, many artifacts, many samples",UPN2_043,9,5070016,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met535Ile/c.1605G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|12|T),2238,23,2266,"0,0101500441",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,52",Neutral,115,Tolerated,"29,56",14
"low bq, low freq, many artifacts, many samples",UPN2_050,9,5070016,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met535Ile/c.1605G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|12|T),2776,31,2819,"0,0109968074",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,52",Neutral,115,Tolerated,"29,29",14
"low bq, low freq, many artifacts, many samples",UPN2_051,9,5070016,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met535Ile/c.1605G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|12|T),6555,70,6657,"0,0105152471",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,52",Neutral,115,Tolerated,"29,38","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_052,9,5070016,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met535Ile/c.1605G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|12|T),3512,45,3569,"0,0126085738",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,52",Neutral,115,Tolerated,"29,31","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_072,9,5070016,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met535Ile/c.1605G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|12|T),2903,42,2962,"0,0141796084",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,52",Neutral,115,Tolerated,"29,73","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_075,9,5070016,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met535Ile/c.1605G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|12|T),13782,156,14032,"0,0111174458",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,52",Neutral,115,Tolerated,"29,74","14,38"
"low bq, low freq, many artifacts",UPN2_079,9,5070016,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met535Ile/c.1605G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|12|T),9084,101,9239,"0,010931919",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,52",Neutral,115,Tolerated,"29,64","14,7"
"low freq, many artifacts",UPN2_045,9,5070020,T,C,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe537Leu/c.1609T>C|1132|JAK2|protein_coding|CODING|ENST00000381652|12|C),2096,27,2126,"0,0126999059",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"31,33","27,26"
"low bq, many samples",UPN2_001,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),2932,93,3029,"0,0307032024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"32,43","14,91"
"low bq, many samples",UPN2_014,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),5335,152,5492,"0,0276766205",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,45","14,35"
"low bq, many samples",UPN2_015,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),9888,277,10178,"0,027215563",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,61","14,7"
"low bq, many samples",UPN2_016,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),4423,117,4543,"0,0257539071",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,39","14,51"
"low bq, many samples",UPN2_017,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),2378,79,2463,"0,0320747056",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,61","14,58"
"low bq, many samples",UPN2_018,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),4734,130,4871,"0,026688565",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,6","14,53"
"low bq, many samples",UPN2_019,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),5544,155,5706,"0,0271643884",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,55","14,74"
"low bq, many samples",UPN2_020,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),2389,59,2450,"0,0240816327",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,13",14
"low bq, many samples",UPN2_021,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),4378,122,4505,"0,0270810211",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,4","14,95"
"low bq, many samples",UPN2_002,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),3792,110,3914,"0,0281042412",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"32,29","14,86"
"low bq, many samples",UPN2_022,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),6704,168,6878,"0,0244257051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,69","14,33"
"low bq, many samples",UPN2_023,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),7643,207,7863,"0,0263258298",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,26","15,02"
"low bq, many samples",UPN2_024,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),2618,80,2711,"0,0295094061",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,36","14,75"
"low bq, many samples",UPN2_025,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),8202,233,8442,"0,0276000948",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,38","14,54"
"low bq, many samples",UPN2_026,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),7857,232,8094,"0,0286632073",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,45","14,59"
"low bq, many samples",UPN2_027,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),10193,292,10497,"0,0278174717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,32","14,54"
"low bq, many samples",UPN2_089,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),6303,201,6516,"0,0308471455",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,91","15,31"
"low bq, many samples",UPN2_028,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),7084,199,7293,"0,0272864391",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,3","15,05"
"low bq, many samples",UPN2_043,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),1739,109,1851,"0,0588870881",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"30,48","15,4"
"low bq, many samples",UPN2_044,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),728,58,788,"0,0736040609",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"29,75","14,81"
"low bq, many samples",UPN2_029,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),5180,169,5353,"0,0315710816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,19","14,63"
"low bq, many samples",UPN2_030,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),6304,186,6497,"0,0286285978",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,42","14,6"
"low bq, many samples",UPN2_031,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),3928,89,4025,"0,0221118012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,53","14,2"
"low bq, many samples",UPN2_005,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),1093,37,1133,"0,0326566637",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"32,23","15,05"
"low bq, many samples",UPN2_045,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),1645,89,1735,"0,05129683",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"30,4","14,78"
"low bq, many samples",UPN2_032,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),2440,58,2504,"0,0231629393",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,41","15,33"
"low bq, many samples",UPN2_046,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),3318,214,3545,"0,0603667137",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"30,21","14,85"
"low bq, many samples",UPN2_033,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),6011,165,6188,"0,026664512",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,45","14,73"
"low bq, many samples",UPN2_034,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),1837,52,1893,"0,0274696249",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,37","14,25"
"low bq, many samples",UPN2_035,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),7328,208,7553,"0,0275387263",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,56","14,54"
"low bq, many samples",UPN2_036,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),5521,164,5699,"0,0287769784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,37","14,8"
"low bq, many samples",UPN2_006,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),991,25,1018,"0,0245579568",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"32,11","14,8"
"low bq, many samples",UPN2_050,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),2256,129,2390,"0,0539748954",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"30,31","15,21"
"low bq, many samples",UPN2_037,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),8783,224,9027,"0,0248144456",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,58","14,68"
"low bq, many samples",UPN2_051,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),5093,258,5369,"0,0480536413",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"30,36","15,29"
"low bq, many samples",UPN2_052,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),2889,169,3066,"0,0551206784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"30,1","15,19"
"low bq, many samples",UPN2_038,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),12124,333,12486,"0,0266698703",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,48","14,71"
"low bq, many samples",UPN2_039,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),11866,335,12219,"0,0274163188",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,51","14,24"
"low bq, many samples",UPN2_053,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),5781,319,6110,"0,0522094926",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"30,59","15,14"
"low bq, many samples",UPN2_054,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),4086,241,4334,"0,0556068297",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"30,44","15,3"
"low bq, many samples",UPN2_007,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),9988,315,10329,"0,0304966599",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"32,25","14,87"
"low bq, many samples",UPN2_008,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),10714,364,11099,"0,0327957474",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"32,13","14,94"
"low bq, many samples",UPN2_009,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),9033,277,9328,"0,0296955403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"32,33","15,36"
"low bq, many samples",UPN2_010,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),9175,307,9494,"0,0323362123",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"32,26","15,26"
"low bq, many samples",UPN2_011,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),8736,289,9043,"0,0319584209",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"32,24","14,96"
"low bq, many samples",UPN2_055,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),3243,165,3413,"0,0483445649",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"30,5","15,11"
"low bq, many samples",UPN2_090,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),4645,129,4775,"0,0270157068",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"32,02","15,83"
"low bq, many samples",UPN2_057,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),3919,239,4173,"0,0572729451",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"30,36","14,81"
"low bq, many samples",UPN2_058,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),7394,429,7837,"0,0547403343",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"30,15","15,29"
"low bq, many samples",UPN2_012,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),3462,105,3575,"0,0293706294",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"32,33","14,73"
"low bq, many samples",UPN2_060,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),8426,192,8638,"0,0222273674",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,9","16,43"
"low bq, many samples",UPN2_040,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),5946,167,6124,"0,0272697583",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,37","14,28"
"low bq, many samples",UPN2_013,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),2717,76,2799,"0,0271525545",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"32,44","14,78"
"low bq, many samples",UPN2_091,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),1678,53,1738,"0,0304948216",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,98","16,55"
"low bq, many samples",UPN2_092,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),2523,78,2602,"0,0299769408",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,6","15,4"
"low bq, many samples",UPN2_093,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),3292,115,3409,"0,0337342329",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,73","15,38"
"low bq, many samples",UPN2_061,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),10208,233,10456,"0,0222838562",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,97","15,91"
"low bq, many samples",UPN2_062,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),8373,203,8604,"0,0235936774",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,97","16,26"
"low bq, many samples",UPN2_063,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),7659,182,7854,"0,0231729055",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,93","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_065,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),1570,34,1604,"0,0211970075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,65","14,38"
"low bq, many samples",UPN2_066,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),22495,547,23076,"0,0237042815",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,78","15,72"
"low bq, many samples",UPN2_067,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),30808,830,31702,"0,0261813135",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,85","16,01"
"low bq, many samples",UPN2_068,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),18643,469,19156,"0,0244831906",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,92","16,28"
"low bq, many samples",UPN2_069,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),16341,404,16790,"0,0240619416",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,79","16,48"
"low bq, low freq, many artifacts, many samples",UPN2_070,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),10470,226,10713,"0,0210958648",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,93","15,76"
"low bq, many samples",UPN2_071,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),7427,204,7656,"0,026645768",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,77","15,62"
"low bq, many samples",UPN2_072,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),2792,64,2858,"0,022393282",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,55",15
"low bq, many samples",UPN2_073,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),1228,31,1263,"0,0245447348",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,75","16,19"
"low bq, many samples",UPN2_074,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),8303,208,8539,"0,0243588242",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"32,05","15,85"
"low bq, many samples",UPN2_075,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),13172,377,13581,"0,0277593697",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,94","15,71"
"low bq, many samples",UPN2_076,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),14452,331,14810,"0,0223497637",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,94","15,82"
"low bq, many samples",UPN2_077,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),18863,481,19368,"0,024834779",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,91","15,87"
"low bq, many samples",UPN2_078,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),13532,342,13892,"0,0246184855",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,97","16,03"
"low bq, many samples",UPN2_079,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),8676,229,8921,"0,025669768",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,68","15,85"
"low bq, many samples",UPN2_080,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),5677,150,5840,"0,0256849315",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,83","16,2"
"low bq, many samples",UPN2_082,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),15416,391,15844,"0,0246781116",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,91","15,9"
"low bq, many samples",UPN2_083,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),17985,431,18473,"0,0233313485",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,32,"16,08"
"low bq, many samples",UPN2_084,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),20973,491,21501,"0,0228361472",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,99","15,61"
"low bq, many samples",UPN2_085,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),34541,827,35442,"0,0233338976",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,85","15,77"
"low bq, many samples",UPN2_086,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),31547,799,32390,"0,0246681074",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,97","16,1"
"low bq, many samples",UPN2_087,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),18348,441,18819,"0,0234337637",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,89","15,45"
"low bq, many samples",UPN2_088,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),14897,368,15295,"0,0240601504",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,95","15,77"
"low bq, many samples",UPN2_094,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),3435,98,3538,"0,0276992651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"32,07","15,55"
"low bq, many samples",UPN2_095,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),4604,140,4746,"0,0294985251",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,98","15,71"
"low bq, many samples",UPN2_096,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),3593,120,3723,"0,0322320709",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,93","14,99"
"low bq, many samples",UPN2_097,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),4385,149,4542,"0,0328049317",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,9","16,02"
"low bq, many samples",UPN2_098,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),3060,80,3145,"0,0254372019",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,96","15,59"
"low bq, many samples",UPN2_099,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),2774,89,2864,"0,031075419",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,99","15,56"
"low bq, many samples",UPN2_100,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),4413,143,4565,"0,0313253012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,65","16,34"
"low bq, many samples",UPN2_101,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),5229,163,5398,"0,030196369",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,89","15,48"
"low bq, many samples",UPN2_102,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),5418,170,5602,"0,0303463049",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,93","15,3"
"low bq, many samples",UPN2_103,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),5222,159,5388,"0,0295100223",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"32,08","15,35"
"low bq, many samples",UPN2_104,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),5678,185,5868,"0,0315269257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"32,05","15,62"
"low bq, many samples",UPN2_105,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),4059,128,4190,"0,030548926",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"32,32","16,17"
"low bq, many samples",UPN2_106,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),1306,45,1354,"0,0332348597",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"32,12","14,58"
"low bq, many samples",UPN2_107,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),8109,250,8373,"0,0298578765",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,82","14,87"
"low bq, many samples",UPN2_108,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),6612,166,6793,"0,0244369204",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,92","15,37"
"low bq, many samples",UPN2_109,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),6857,201,7073,"0,0284179273",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,9","15,59"
"low bq, many samples",UPN2_110,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),4593,132,4733,"0,027889288",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,78","15,48"
low bq,UPN2_111,9,5070023,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His538Asn/c.1612C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|12|A),7855,216,8081,"0,0267293652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,13,Damaging,"31,97","15,91"
"low bq, low freq, many artifacts, many samples",UPN2_052,9,5070028,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys539Asn/c.1617A>T|1132|JAK2|protein_coding|CODING|ENST00000381652|12|T),1751,21,1777,"0,0118176702",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,87",Deleterious,8,Damaging,"33,47","20,1"
"low bq, low freq, many artifacts, many samples",UPN2_055,9,5070028,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys539Asn/c.1617A>T|1132|JAK2|protein_coding|CODING|ENST00000381652|12|T),2093,23,2123,"0,0108337259",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,87",Deleterious,8,Damaging,"33,63","19,74"
"low bq, low freq, many artifacts, many samples",UPN2_052,9,5070034,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg541Ser/c.1623A>T|1132|JAK2|protein_coding|CODING|ENST00000381652|12|T),1753,22,1778,"0,0123734533",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,328,Tolerated,"34,09","18,05"
"low bq, low freq, many artifacts, many samples",UPN2_046,9,5070039,A,T,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu543Val/c.1628A>T|1132|JAK2|protein_coding|CODING|ENST00000381652|12|T),1960,21,1989,"0,0105580694",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,2,Damaging,"33,41",14
"low bq, low freq, many artifacts, many samples",UPN2_051,9,5070039,A,T,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu543Val/c.1628A>T|1132|JAK2|protein_coding|CODING|ENST00000381652|12|T),3253,38,3307,"0,0114907771",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,2,Damaging,"33,35","20,16"
"low bq, low freq, many artifacts, many samples",UPN2_052,9,5070039,A,T,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu543Val/c.1628A>T|1132|JAK2|protein_coding|CODING|ENST00000381652|12|T),1753,20,1779,"0,0112422709",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,2,Damaging,"33,71","20,4"
"low bq, low freq, many artifacts",UPN2_055,9,5070039,A,T,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu543Val/c.1628A>T|1132|JAK2|protein_coding|CODING|ENST00000381652|12|T),2099,22,2126,"0,0103480715",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,2,Damaging,"33,24","20,59"
"low bq, low freq, many artifacts",UPN2_050,9,5070040,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu543Asp/c.1629A>T|1132|JAK2|protein_coding|CODING|ENST00000381652|12|T),1369,22,1402,"0,0156918688",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,449,Tolerated,"34,25",22
"low bq, many samples",UPN2_001,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),6281,142,6452,"0,0220086795",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,31,"14,73"
"low bq, low freq, many artifacts, many samples",UPN2_018,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),7089,75,7193,"0,0104268038",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"30,8","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_002,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),8054,128,8233,"0,0155471881",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"31,12","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_003,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),1560,27,1591,"0,0169704588",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"30,74","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_025,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),12481,140,12666,"0,0110532133",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"31,01","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_004,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),1511,22,1540,"0,0142857143",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"31,13",14
"low bq, low freq, many artifacts, many samples",UPN2_042,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),3368,37,3421,"0,010815551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"30,25","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_043,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),5869,73,5974,"0,0122196183",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"30,24","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_005,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),2323,46,2378,"0,0193439865",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"30,89",14
"low bq, low freq, many artifacts, many samples",UPN2_046,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),7907,92,8026,"0,0114627461",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"30,45","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_033,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),8791,100,8927,"0,0112019715",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"31,06","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_034,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),2957,37,3011,"0,0122882763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"30,97","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_047,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),2684,34,2731,"0,0124496521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"30,15","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_036,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),9891,108,10042,"0,0107548297",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"30,8","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_049,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),2473,35,2517,"0,013905443",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"30,28","14,2"
"low bq, low freq, many artifacts, many samples",UPN2_050,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),6696,72,6807,"0,0105773468",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"30,17","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_051,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),8751,140,8947,"0,0156477031",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"30,12","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_052,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),7049,85,7167,"0,0118599135",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"30,3","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_053,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),11061,146,11270,"0,0129547471",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"30,39","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_054,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),8077,101,8217,"0,0122915906",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"30,41","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_007,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),19501,358,19926,"0,017966476",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"30,91","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_008,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),23087,387,23579,"0,0164129098",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"31,13","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_009,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),19581,315,19984,"0,0157626101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"30,97","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_010,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),15731,276,16072,"0,0171727227",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"31,06","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_011,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),18191,309,18567,"0,0166424301",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"30,9","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_055,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),8951,116,9127,"0,0127095431",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"30,28","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_057,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),10897,130,11087,"0,0117254442",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"30,11","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_058,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),11298,142,11497,"0,0123510481",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"30,34","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_012,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),6664,103,6786,"0,0151783083",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"31,02",14
"low bq, low freq, many artifacts, many samples",UPN2_040,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),10492,113,10639,"0,010621299",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"30,9","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_013,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),5228,88,5344,"0,0164670659",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"30,92","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_061,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),8440,99,8596,"0,0115169846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"30,97","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_064,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),1320,22,1351,"0,0162842339",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"30,89",14
"low bq, low freq, many artifacts, many samples",UPN2_066,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),15983,171,16279,"0,0105043307",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"30,73","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_067,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),17828,218,18163,"0,0120024225",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"30,92","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_073,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),3018,32,3064,"0,0104438642",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"31,03","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_075,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),8571,104,8729,"0,0119143086",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"30,63","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_077,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),11429,122,11631,"0,0104892099",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"31,06","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_078,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),7834,80,7964,"0,0100452034",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"31,08","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_079,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),5535,58,5629,"0,010303784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"31,18","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_081,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),2176,23,2221,"0,0103556956",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"30,54",14
"low bq, low freq, many artifacts, many samples",UPN2_082,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),12334,128,12545,"0,0102032682",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"30,78","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_085,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),16356,168,16645,"0,0100931211",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"30,9","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_088,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),11386,134,11579,"0,0115726747",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"30,77","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_099,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),3269,34,3321,"0,0102378802",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"31,06","15,18"
"low bq, low freq, many artifacts",UPN2_100,9,5073699,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser593Tyr/c.1778C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),5274,61,5367,"0,0113657537",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,1,Damaging,"31,07","14,87"
"low freq, many artifacts",UPN2_006,9,5073699,CTT,C,frameshift_variant(HIGH||ttc/|p.Phe594fs/c.1780_1781delTT|1132|JAK2|protein_coding|CODING|ENST00000381652|14|C|INFO_REALIGN_3_PRIME),4234,64,4322,"0,0148079593",0,0,0,1,1,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,86",NA
"low bq, low freq, many artifacts, many samples",UPN2_001,9,5073703,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe594Leu/c.1782C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),6327,104,6452,"0,0161190329",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,3",Deleterious,37,Damaging,"31,88","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_017,9,5073703,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe594Leu/c.1782C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),3659,46,3716,"0,012378902",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,3",Deleterious,37,Damaging,"32,28","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_002,9,5073703,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe594Leu/c.1782C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),8119,94,8233,"0,0114174663",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,3",Deleterious,37,Damaging,"31,9","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_042,9,5073703,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe594Leu/c.1782C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),3371,36,3420,"0,0105263158",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,3",Deleterious,37,Damaging,"31,26","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_043,9,5073703,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe594Leu/c.1782C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),5869,83,5974,"0,0138935387",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,3",Deleterious,37,Damaging,"31,23","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_005,9,5073703,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe594Leu/c.1782C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),2326,44,2378,"0,0185029437",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,3",Deleterious,37,Damaging,"31,79",15
"low bq, low freq, many artifacts, many samples",UPN2_045,9,5073703,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe594Leu/c.1782C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),5741,69,5827,"0,0118414278",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,3",Deleterious,37,Damaging,"31,25","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_046,9,5073703,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe594Leu/c.1782C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),7898,85,8023,"0,0105945407",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,3",Deleterious,37,Damaging,"31,29","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_033,9,5073703,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe594Leu/c.1782C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),8811,91,8927,"0,0101937941",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,3",Deleterious,37,Damaging,"31,96","14,08"
"low bq, low freq, many artifacts, many samples",UPN2_034,9,5073703,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe594Leu/c.1782C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),2969,31,3011,"0,0102955829",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,3",Deleterious,37,Damaging,"31,85",14
"low bq, low freq, many artifacts, many samples",UPN2_047,9,5073703,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe594Leu/c.1782C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),2684,29,2731,"0,0106188209",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,3",Deleterious,37,Damaging,"31,25","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_006,9,5073703,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe594Leu/c.1782C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),4254,56,4320,"0,012962963",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,3",Deleterious,37,Damaging,"31,92","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_049,9,5073703,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe594Leu/c.1782C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),2476,28,2516,"0,0111287758",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,3",Deleterious,37,Damaging,"31,31","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_050,9,5073703,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe594Leu/c.1782C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),6681,79,6807,"0,0116057",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,3",Deleterious,37,Damaging,"31,03","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_052,9,5073703,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe594Leu/c.1782C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),7050,88,7167,"0,0122784987",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,3",Deleterious,37,Damaging,"31,48","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_053,9,5073703,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe594Leu/c.1782C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),11085,122,11269,"0,0108261603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,3",Deleterious,37,Damaging,"31,28","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_054,9,5073703,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe594Leu/c.1782C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),8076,98,8217,"0,0119264939",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,3",Deleterious,37,Damaging,"31,42","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_007,9,5073703,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe594Leu/c.1782C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),19582,283,19924,"0,0142039751",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,3",Deleterious,37,Damaging,"31,68","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_008,9,5073703,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe594Leu/c.1782C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),23178,309,23578,"0,0131054373",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,3",Deleterious,37,Damaging,"31,97","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_009,9,5073703,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe594Leu/c.1782C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),19641,267,19982,"0,0133620258",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,3",Deleterious,37,Damaging,"31,82","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_010,9,5073703,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe594Leu/c.1782C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),15782,235,16070,"0,0146235221",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,3",Deleterious,37,Damaging,"31,8","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_011,9,5073703,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe594Leu/c.1782C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),18248,265,18564,"0,0142749407",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,3",Deleterious,37,Damaging,"31,78","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_057,9,5073703,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe594Leu/c.1782C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),10881,145,11087,"0,0130783801",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,3",Deleterious,37,Damaging,"31,08","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_058,9,5073703,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe594Leu/c.1782C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),11295,140,11496,"0,0121781489",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,3",Deleterious,37,Damaging,"31,25","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_012,9,5073703,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe594Leu/c.1782C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),6673,88,6786,"0,012967875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,3",Deleterious,37,Damaging,"31,85","14,08"
"low bq, low freq, many artifacts, many samples",UPN2_040,9,5073703,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe594Leu/c.1782C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),10490,114,10637,"0,0107173075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,3",Deleterious,37,Damaging,"31,76","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_013,9,5073703,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe594Leu/c.1782C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),5235,84,5345,"0,0157156221",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,3",Deleterious,37,Damaging,"31,89","14,61"
"low bq, low freq, many artifacts",UPN2_075,9,5073703,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe594Leu/c.1782C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),8588,96,8730,"0,0109965636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,3",Deleterious,37,Damaging,"31,55","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_042,9,5073714,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala598Glu/c.1793C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),3353,41,3418,"0,0119953189",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,0,Damaging,"32,7","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_043,9,5073714,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala598Glu/c.1793C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),5880,75,5969,"0,0125649187",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,0,Damaging,"32,65","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_045,9,5073714,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala598Glu/c.1793C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),5734,66,5824,"0,0113324176",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,0,Damaging,"32,65","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_046,9,5073714,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala598Glu/c.1793C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),7906,86,8018,"0,0107258668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,0,Damaging,"32,75","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_047,9,5073714,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala598Glu/c.1793C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),2689,36,2731,"0,0131819846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,0,Damaging,"32,61","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_050,9,5073714,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala598Glu/c.1793C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),6700,81,6804,"0,0119047619",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,0,Damaging,"32,55","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_051,9,5073714,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala598Glu/c.1793C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),8808,94,8938,"0,0105168942",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,0,Damaging,"32,64","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_052,9,5073714,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala598Glu/c.1793C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),7066,72,7166,"0,0100474463",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,0,Damaging,"32,74","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_053,9,5073714,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala598Glu/c.1793C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),11095,135,11258,"0,0119914727",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,0,Damaging,"32,74","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_054,9,5073714,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala598Glu/c.1793C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),8087,87,8211,"0,0105955426",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,0,Damaging,"32,72","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_055,9,5073714,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala598Glu/c.1793C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),8956,110,9121,"0,0120600811",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,0,Damaging,"32,67","14,2"
"low bq, low freq, many artifacts, many samples",UPN2_057,9,5073714,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala598Glu/c.1793C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),10881,141,11085,"0,0127198917",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,0,Damaging,"32,51","16,57"
"low bq, low freq, many artifacts, many samples",UPN2_058,9,5073714,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala598Glu/c.1793C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),11339,125,11492,"0,0108771319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,0,Damaging,"32,65","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_065,9,5073714,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala598Glu/c.1793C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),3796,47,3854,"0,012195122",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,0,Damaging,"32,52",14
"low bq, low freq, many artifacts, many samples",UPN2_066,9,5073714,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala598Glu/c.1793C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),16047,175,16258,"0,0107639316",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,0,Damaging,"32,5","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_096,9,5073714,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala598Glu/c.1793C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),4652,50,4715,"0,0106044539",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,0,Damaging,"33,25",14
"low bq, low freq, many artifacts",UPN2_107,9,5073714,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala598Glu/c.1793C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),10654,119,10800,"0,0110185185",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,0,Damaging,"33,23","15,92"
"low freq, many artifacts",UPN2_006,9,5073722,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met601Leu/c.1801A>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),4227,70,4321,"0,0161999537",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,"0,006",Damaging,"35,1","34,26"
"low bq, low freq, many artifacts, many samples",UPN2_042,9,5073727,C,A,missense_variant(MODERATE|MISSENSE|agC/agA|p.Ser602Arg/c.1806C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),3374,36,3418,"0,0105324751",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,286,Tolerated,"32,57","16,33"
"low bq, low freq, many artifacts, many samples",UPN2_043,9,5073727,C,A,missense_variant(MODERATE|MISSENSE|agC/agA|p.Ser602Arg/c.1806C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),5886,60,5969,"0,010051935",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,286,Tolerated,"32,43","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_047,9,5073727,C,A,missense_variant(MODERATE|MISSENSE|agC/agA|p.Ser602Arg/c.1806C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),2699,28,2730,"0,0102564103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,286,Tolerated,"32,39","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_050,9,5073727,C,A,missense_variant(MODERATE|MISSENSE|agC/agA|p.Ser602Arg/c.1806C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),6694,74,6797,"0,0108871561",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,286,Tolerated,"32,43","14,18"
"low bq, low freq, many artifacts, many samples",UPN2_051,9,5073727,C,A,missense_variant(MODERATE|MISSENSE|agC/agA|p.Ser602Arg/c.1806C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),8821,90,8932,"0,0100761308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,286,Tolerated,"32,59","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_090,9,5073727,C,A,missense_variant(MODERATE|MISSENSE|agC/agA|p.Ser602Arg/c.1806C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),5069,55,5135,"0,0107108082",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,286,Tolerated,"32,89","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_060,9,5073727,C,A,missense_variant(MODERATE|MISSENSE|agC/agA|p.Ser602Arg/c.1806C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),7808,95,7927,"0,0119843573",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,286,Tolerated,"31,76","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_062,9,5073727,C,A,missense_variant(MODERATE|MISSENSE|agC/agA|p.Ser602Arg/c.1806C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),5957,69,6033,"0,011437096",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,286,Tolerated,"31,99","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_063,9,5073727,C,A,missense_variant(MODERATE|MISSENSE|agC/agA|p.Ser602Arg/c.1806C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),6635,74,6717,"0,011016823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,286,Tolerated,"31,89","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_065,9,5073727,C,A,missense_variant(MODERATE|MISSENSE|agC/agA|p.Ser602Arg/c.1806C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),3802,40,3849,"0,0103923097",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,286,Tolerated,"31,69","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_066,9,5073727,C,A,missense_variant(MODERATE|MISSENSE|agC/agA|p.Ser602Arg/c.1806C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),15977,235,16233,"0,0144766833",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,286,Tolerated,"31,74","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_067,9,5073727,C,A,missense_variant(MODERATE|MISSENSE|agC/agA|p.Ser602Arg/c.1806C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),17875,224,18123,"0,0123599846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,286,Tolerated,"31,76","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_070,9,5073727,C,A,missense_variant(MODERATE|MISSENSE|agC/agA|p.Ser602Arg/c.1806C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),7496,94,7608,"0,0123554154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,286,Tolerated,"31,91","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_071,9,5073727,C,A,missense_variant(MODERATE|MISSENSE|agC/agA|p.Ser602Arg/c.1806C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),4061,48,4111,"0,0116759912",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,286,Tolerated,"31,84",14
"low bq, low freq, many artifacts, many samples",UPN2_073,9,5073727,C,A,missense_variant(MODERATE|MISSENSE|agC/agA|p.Ser602Arg/c.1806C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),3026,32,3062,"0,0104506858",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,286,Tolerated,"32,11","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_074,9,5073727,C,A,missense_variant(MODERATE|MISSENSE|agC/agA|p.Ser602Arg/c.1806C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),6883,114,7012,"0,0162578437",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,286,Tolerated,"31,84","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_075,9,5073727,C,A,missense_variant(MODERATE|MISSENSE|agC/agA|p.Ser602Arg/c.1806C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),8578,100,8717,"0,0114718366",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,286,Tolerated,"31,69","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_077,9,5073727,C,A,missense_variant(MODERATE|MISSENSE|agC/agA|p.Ser602Arg/c.1806C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),11466,118,11610,"0,010163652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,286,Tolerated,"32,02","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_079,9,5073727,C,A,missense_variant(MODERATE|MISSENSE|agC/agA|p.Ser602Arg/c.1806C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),5539,68,5622,"0,0120953397",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,286,Tolerated,"31,86","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_082,9,5073727,C,A,missense_variant(MODERATE|MISSENSE|agC/agA|p.Ser602Arg/c.1806C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),12320,190,12536,"0,0151563497",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,286,Tolerated,"31,73","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_085,9,5073727,C,A,missense_variant(MODERATE|MISSENSE|agC/agA|p.Ser602Arg/c.1806C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),16370,198,16606,"0,0119234012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,286,Tolerated,"31,91","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_087,9,5073727,C,A,missense_variant(MODERATE|MISSENSE|agC/agA|p.Ser602Arg/c.1806C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),12924,178,13124,"0,0135629381",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,286,Tolerated,"31,69","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_088,9,5073727,C,A,missense_variant(MODERATE|MISSENSE|agC/agA|p.Ser602Arg/c.1806C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),11412,133,11559,"0,0115061857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,286,Tolerated,"31,79","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_096,9,5073727,C,A,missense_variant(MODERATE|MISSENSE|agC/agA|p.Ser602Arg/c.1806C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),4650,49,4710,"0,010403397",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,286,Tolerated,"32,82","15,78"
"low bq, low freq, many artifacts",UPN2_104,9,5073727,C,A,missense_variant(MODERATE|MISSENSE|agC/agA|p.Ser602Arg/c.1806C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),6339,70,6418,"0,0109068246",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,286,Tolerated,"32,82","14,1"
"low bq, low freq, many artifacts, many samples",UPN2_001,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),6335,96,6442,"0,0149022043",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,88","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_014,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),8865,103,8987,"0,0114609992",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,15","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_015,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),13261,142,13435,"0,0105694083",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,07","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_016,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),6570,78,6657,"0,0117169896",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,14",14
"low bq, low freq, many artifacts, many samples",UPN2_017,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),3666,38,3713,"0,0102343119",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,46","15,74"
"low bq, low freq, many artifacts, many samples",UPN2_018,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),7100,79,7188,"0,0109905398",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,09",14
"low bq, low freq, many artifacts, many samples",UPN2_019,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),8307,89,8424,"0,0105650522",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,11","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_002,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),8069,131,8227,"0,0159231798",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,85","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_003,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),1564,21,1590,"0,0132075472",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,29","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_022,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),10670,117,10810,"0,0108233117",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,25","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_023,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),11460,132,11614,"0,0113655932",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,17","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_024,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),4372,49,4430,"0,0110609481",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,33","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_025,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),12488,146,12659,"0,0115332965",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,29","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_026,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),11786,142,11958,"0,0118748955",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,35","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_004,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),1510,28,1540,"0,0181818182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,82",14
"low bq, low freq, many artifacts, many samples",UPN2_027,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),15060,168,15267,"0,0110041265",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,19","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_042,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),3374,40,3424,"0,011682243",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,39",14
"low bq, low freq, many artifacts, many samples",UPN2_029,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),10091,106,10212,"0,0103799452",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,25","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_030,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),10178,105,10307,"0,0101872514",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,19","14,13"
"low bq, low freq, many artifacts, many samples",UPN2_031,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),6444,71,6528,"0,0108762255",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,21",14
"low bq, low freq, many artifacts, many samples",UPN2_005,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),2329,38,2370,"0,0160337553",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,71",14
"low bq, low freq, many artifacts, many samples",UPN2_032,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),4231,55,4297,"0,0127996276",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,37",14
"low bq, low freq, many artifacts, many samples",UPN2_033,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),8810,91,8917,"0,010205226",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,37","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_047,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),2693,29,2729,"0,0106266032",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,39","15,34"
"low bq, low freq, many artifacts, many samples",UPN2_035,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),12943,133,13099,"0,0101534468",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,09","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_036,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),9895,116,10027,"0,0115687643",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"29,97","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_006,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),4248,62,4317,"0,0143618253",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,8","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_049,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),2469,29,2510,"0,0115537849",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,67",14
"low bq, low freq, many artifacts, many samples",UPN2_050,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),6684,88,6796,"0,0129487934",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,46","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_037,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),12899,132,13068,"0,0101010101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,34","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_051,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),8797,95,8930,"0,0106382979",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,54","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_052,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),7052,80,7159,"0,0111747451",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,56","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_038,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),17564,214,17816,"0,0120116749",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,16","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_053,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),11075,133,11253,"0,0118190705",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,53","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_054,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),8083,90,8204,"0,0109702584",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,57","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_007,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),19550,328,19912,"0,0164724789",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,77","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_008,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),23148,348,23558,"0,014772052",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,94","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_009,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),19583,322,19955,"0,0161363067",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,69","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_010,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),15749,269,16045,"0,0167653475",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,67","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_011,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),18195,311,18537,"0,0167772563",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,81","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_055,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),8989,102,9116,"0,011189118",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,44","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_057,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),10915,123,11081,"0,0111000812",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,32","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_058,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),11306,141,11478,"0,0122843701",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,46","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_012,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),6638,128,6776,"0,0188902007",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,85","14,2"
"low bq, low freq, many artifacts, many samples",UPN2_040,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),10483,123,10630,"0,0115710254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,24","14,18"
"low bq, low freq, many artifacts, many samples",UPN2_013,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),5237,81,5332,"0,0151912978",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"30,68","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_065,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),3794,39,3849,"0,0101325019",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"29,83",14
"low bq, low freq, many artifacts, many samples",UPN2_066,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),15981,169,16228,"0,0104140991",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"29,74","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_067,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),17844,196,18119,"0,010817374",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"29,89","14,2"
"low bq, low freq, many artifacts, many samples",UPN2_075,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),8564,100,8714,"0,0114757861",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"29,76","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_082,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),12320,145,12532,"0,0115703798",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"29,76","14,48"
"low bq, low freq, many artifacts",UPN2_088,9,5073731,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu604Ile/c.1810C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),11394,119,11550,"0,0103030303",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,27",Tolerated,"29,81","14,76"
"low bq, many samples",UPN2_001,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),6392,210,6637,"0,0316408016",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,89","14,29"
"low bq, many samples",UPN2_014,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),9045,223,9295,"0,0239913932",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,12","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_015,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),13533,275,13841,"0,0198685066",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,12","14,25"
"low bq, many samples",UPN2_016,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),6690,154,6853,"0,0224719101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,34","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_017,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),3783,69,3857,"0,0178895515",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,54","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_018,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),7186,153,7367,"0,020768291",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,11","14,27"
"low bq, many samples",UPN2_019,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),8421,223,8670,"0,0257208766",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,2","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_020,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),5172,103,5286,"0,0194854332",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,19","14,07"
"low bq, low freq, many artifacts, many samples",UPN2_021,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),7237,158,7422,"0,0212880625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,22","14,2"
"low bq, many samples",UPN2_002,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),8219,217,8457,"0,0256592172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,9","14,16"
"low bq, many samples",UPN2_003,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),1587,40,1632,"0,0245098039",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,41","15,1"
"low bq, many samples",UPN2_022,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),10876,254,11153,"0,0227741415",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,29","14,37"
"low bq, many samples",UPN2_023,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),11689,269,11986,"0,02244285",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,29","14,43"
"low bq, many samples",UPN2_024,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),4453,106,4568,"0,0232049037",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,42","14,21"
"low bq, many samples",UPN2_025,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),12696,298,13020,"0,0228878648",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,33","14,1"
"low bq, low freq, many artifacts, many samples",UPN2_026,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),12058,249,12343,"0,0201733776",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,32","14,69"
"low bq, many samples",UPN2_004,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),1556,50,1611,"0,0310366232",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,81","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_027,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),15443,298,15789,"0,0188738996",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,14","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_089,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),6712,86,6826,"0,0125988866",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,79","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_042,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),3449,72,3547,"0,0202988441",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,46",14
"low bq, low freq, many artifacts, many samples",UPN2_028,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),10717,236,10984,"0,0214857975",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,29","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_043,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),6018,100,6148,"0,0162654522",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,43","14,29"
"low bq, many samples",UPN2_044,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),1494,36,1534,"0,0234680574",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,44",14
"low bq, low freq, many artifacts, many samples",UPN2_029,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),10292,222,10541,"0,0210606204",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,32","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_030,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),10403,232,10686,"0,0217106494",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,34","14,19"
"low bq, many samples",UPN2_031,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),6573,163,6752,"0,0241409953",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,25","14,04"
"low bq, many samples",UPN2_005,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),2362,64,2434,"0,026294166",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,52","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_045,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),5897,116,6039,"0,0192084782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,37","14,3"
"low bq, many samples",UPN2_032,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),4322,101,4429,"0,0228042448",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,42",14
"low bq, low freq, many artifacts, many samples",UPN2_046,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),8059,160,8249,"0,0193962905",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,65","14,2"
"low bq, many samples",UPN2_033,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),8966,210,9202,"0,0228211258",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,41","14,03"
"low bq, many samples",UPN2_034,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),3031,79,3124,"0,0252880922",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,31",14
"low bq, many samples",UPN2_047,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),2732,67,2810,"0,0238434164",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,42","14,3"
"low bq, many samples",UPN2_035,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),13173,302,13525,"0,0223290203",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,1","14,11"
"low bq, many samples",UPN2_036,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),10032,248,10298,"0,0240823461",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,23","14,27"
"low bq, many samples",UPN2_006,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),4319,114,4439,"0,0256814598",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,72","14,19"
"low bq, low freq, many artifacts, many samples",UPN2_049,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),2521,55,2587,"0,0212601469",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,44","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_050,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),6813,142,6978,"0,0203496704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,59","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_037,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),13175,254,13461,"0,0188693262",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,43","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_051,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),8954,197,9189,"0,0214386767",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,49","14,24"
"low bq, many samples",UPN2_052,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),7146,171,7350,"0,0232653061",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,76","14,34"
"low bq, many samples",UPN2_038,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),17878,452,18381,"0,0245906099",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,29","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_039,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),20881,460,21397,"0,0214983409",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,07","14,18"
"low bq, low freq, many artifacts, many samples",UPN2_053,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),11316,198,11588,"0,0170866414",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,58","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_054,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),8242,165,8449,"0,0195289383",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,54","14,63"
"low bq, many samples",UPN2_007,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),19752,621,20426,"0,0304024283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,82","14,27"
"low bq, many samples",UPN2_008,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),23509,651,24211,"0,0268886044",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,88","14,26"
"low bq, many samples",UPN2_009,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),19859,578,20480,"0,0282226563",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,78","14,33"
"low bq, many samples",UPN2_010,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),15989,465,16491,"0,0281971985",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,65","14,12"
"low bq, many samples",UPN2_011,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),18429,559,19039,"0,0293607858",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,62","14,2"
"low bq, many samples",UPN2_055,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),9150,222,9407,"0,0235994472",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,52","14,19"
"low bq, low freq, many artifacts, many samples",UPN2_090,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),5113,76,5216,"0,0145705521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,82","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_057,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),11156,240,11443,"0,0209735209",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,41","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_058,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),11472,252,11781,"0,0213903743",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,67","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_059,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),1042,23,1076,"0,0213754647",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"28,76","14,61"
"low bq, many samples",UPN2_012,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),6772,188,6976,"0,0269495413",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,72",14
"low bq, low freq, many artifacts, many samples",UPN2_060,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),7928,153,8149,"0,0187753099",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"28,97","14,42"
"low bq, many samples",UPN2_040,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),10695,254,10975,"0,023143508",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,2","14,65"
"low bq, many samples",UPN2_013,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),5310,158,5479,"0,0288373791",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,75","14,2"
"low bq, low freq, many artifacts, many samples",UPN2_091,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),3571,75,3668,"0,0204471101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,67","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_092,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),3243,60,3316,"0,0180940893",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,42",14
"low bq, low freq, many artifacts, many samples",UPN2_093,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),4028,59,4109,"0,0143587248",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,29","14,12"
"low bq, low freq, many artifacts, many samples",UPN2_061,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),8550,182,8797,"0,0206888712",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,03","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_062,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),6037,112,6195,"0,018079096",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,12","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_063,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),6714,139,6901,"0,0201420084",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,14","14,41"
"low bq, many samples",UPN2_064,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),1332,38,1384,"0,0274566474",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,05","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_065,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),3834,84,3951,"0,0212604404",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,02",14
"low bq, low freq, many artifacts, many samples",UPN2_066,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),16188,321,16659,"0,0192688637",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"28,98","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_067,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),18073,398,18616,"0,0213794585",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,11","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_068,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),11942,233,12265,"0,0189971464",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,19","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_069,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),10731,236,11074,"0,0213111793",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"28,97","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_070,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),7643,141,7835,"0,017996171",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,21","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_071,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),4097,88,4225,"0,0208284024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,07","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_072,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),3500,67,3586,"0,0186837702",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,18","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_073,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),3043,66,3126,"0,0211132438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,3","14,44"
"low bq, many samples",UPN2_074,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),6935,166,7189,"0,0230908332",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,25","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_075,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),8675,179,8930,"0,0200447928",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,01","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_076,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),9671,199,9957,"0,0199859395",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,31","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_077,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),11648,208,11947,"0,0174102285",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,06","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_078,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),7922,125,8104,"0,0154244817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,22","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_079,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),5632,104,5781,"0,0179899671",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,02","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_080,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),6657,134,6838,"0,0195963732",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,24","14,89"
"low bq, many samples",UPN2_081,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),2189,51,2264,"0,0225265018",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"28,93","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_082,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),12488,263,12859,"0,0204526013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"28,95","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_083,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),11724,215,12036,"0,0178630774",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,3","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_084,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),12824,240,13196,"0,0181873295",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,28","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_085,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),16610,322,17080,"0,018852459",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,02","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_086,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),14841,265,15233,"0,0173964419",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"28,98","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_087,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),13136,269,13511,"0,0199097032",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,07","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_088,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),11487,248,11828,"0,0209671965",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"28,97","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_094,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),5061,77,5171,"0,0148907368",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,47","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_095,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),6308,89,6428,"0,0138456752",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,63","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_096,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),4695,82,4799,"0,0170868931",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,7","14,09"
"low bq, low freq, many artifacts, many samples",UPN2_097,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),5700,83,5816,"0,0142709766",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,59","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_098,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),4537,78,4642,"0,0168031021",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,5","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_099,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),3310,56,3378,"0,0165778567",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,68","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_100,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),5375,83,5483,"0,0151376983",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,46","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_101,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),6028,91,6144,"0,0148111979",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,81","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_102,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),6503,114,6648,"0,0171480144",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,3","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_103,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),6155,92,6289,"0,0146287168",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,53","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_104,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),6380,106,6517,"0,0162651527",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,69","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_105,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),5295,72,5399,"0,0133358029",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,6","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_106,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),3648,62,3731,"0,0166175288",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,57","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_107,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),10775,183,11021,"0,0166046638",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,52","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_108,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),8537,132,8731,"0,0151185431",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,45","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_109,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),9127,135,9309,"0,0145020947",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,61","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_110,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),7105,111,7246,"0,0153187966",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,51","14,06"
"low bq, low freq, many artifacts",UPN2_111,9,5073735,C,A,missense_variant(MODERATE|MISSENSE|tCt/tAt|p.Ser605Tyr/c.1814C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),8713,137,8897,"0,0153984489",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,0,Damaging,"29,53","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_001,9,5073737,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His606Asn/c.1816C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),12700,136,12848,"0,0105853051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,99",Deleterious,1,Damaging,"31,79","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_005,9,5073737,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His606Asn/c.1816C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),4652,49,4729,"0,0103615986",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,99",Deleterious,1,Damaging,"31,9","15,61"
"low bq, low freq, many artifacts, many samples",UPN2_050,9,5073737,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His606Asn/c.1816C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),13207,135,13384,"0,0100866707",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,99",Deleterious,1,Damaging,"30,41","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_009,9,5073737,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His606Asn/c.1816C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),39286,413,39778,"0,0103826236",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,99",Deleterious,1,Damaging,"31,84","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_059,9,5073737,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His606Asn/c.1816C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),2027,34,2067,"0,0164489598",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,99",Deleterious,1,Damaging,"29,43","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_012,9,5073737,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His606Asn/c.1816C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),13346,140,13506,"0,0103657634",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,99",Deleterious,1,Damaging,"31,9","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_060,9,5073737,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His606Asn/c.1816C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),15375,173,15611,"0,0110819294",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,99",Deleterious,1,Damaging,"29,57","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_013,9,5073737,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His606Asn/c.1816C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),10482,110,10611,"0,0103666007",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,99",Deleterious,1,Damaging,"31,79","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_061,9,5073737,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His606Asn/c.1816C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),16618,214,16911,"0,0126544852",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,99",Deleterious,1,Damaging,"29,64","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_062,9,5073737,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His606Asn/c.1816C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),11725,147,11905,"0,012347753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,99",Deleterious,1,Damaging,"29,76","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_063,9,5073737,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His606Asn/c.1816C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),13057,154,13273,"0,0116025013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,99",Deleterious,1,Damaging,"29,7","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_064,9,5073737,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His606Asn/c.1816C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),2614,39,2661,"0,0146561443",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,99",Deleterious,1,Damaging,"29,46",14
"low bq, low freq, many artifacts, many samples",UPN2_065,9,5073737,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His606Asn/c.1816C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),7415,101,7589,"0,0133087363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,99",Deleterious,1,Damaging,"29,39","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_066,9,5073737,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His606Asn/c.1816C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),31493,384,32024,"0,0119910067",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,99",Deleterious,1,Damaging,"29,5","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_067,9,5073737,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His606Asn/c.1816C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),35075,492,35704,"0,0137799686",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,99",Deleterious,1,Damaging,"29,51","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_068,9,5073737,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His606Asn/c.1816C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),23085,261,23452,"0,0111291148",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,99",Deleterious,1,Damaging,"29,75","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_069,9,5073737,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His606Asn/c.1816C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),20819,251,21141,"0,0118726645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,99",Deleterious,1,Damaging,"29,6","14,2"
"low bq, low freq, many artifacts, many samples",UPN2_070,9,5073737,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His606Asn/c.1816C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),14767,185,15019,"0,0123177309",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,99",Deleterious,1,Damaging,"29,71","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_071,9,5073737,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His606Asn/c.1816C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),7955,120,8104,"0,0148075025",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,99",Deleterious,1,Damaging,"29,63","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_072,9,5073737,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His606Asn/c.1816C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),6803,83,6917,"0,0119994217",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,99",Deleterious,1,Damaging,"29,73",14
"low bq, low freq, many artifacts, many samples",UPN2_073,9,5073737,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His606Asn/c.1816C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),5941,73,6031,"0,0121041287",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,99",Deleterious,1,Damaging,"29,59","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_074,9,5073737,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His606Asn/c.1816C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),13570,196,13822,"0,0141802923",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,99",Deleterious,1,Damaging,"29,57","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_075,9,5073737,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His606Asn/c.1816C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),16907,223,17189,"0,0129734132",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,99",Deleterious,1,Damaging,"29,45","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_076,9,5073737,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His606Asn/c.1816C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),18779,228,19063,"0,011960342",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,99",Deleterious,1,Damaging,"29,79","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_077,9,5073737,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His606Asn/c.1816C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),22554,282,22929,"0,0122988355",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,99",Deleterious,1,Damaging,"29,76","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_078,9,5073737,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His606Asn/c.1816C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),15467,177,15688,"0,0112825089",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,99",Deleterious,1,Damaging,"29,77","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_079,9,5073737,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His606Asn/c.1816C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),10912,128,11088,"0,0115440115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,99",Deleterious,1,Damaging,"29,63","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_080,9,5073737,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His606Asn/c.1816C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),13032,148,13227,"0,0111892341",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,99",Deleterious,1,Damaging,"29,54","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_081,9,5073737,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His606Asn/c.1816C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),4306,58,4380,"0,0132420091",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,99",Deleterious,1,Damaging,"29,45","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_082,9,5073737,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His606Asn/c.1816C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),24221,315,24664,"0,012771651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,99",Deleterious,1,Damaging,"29,52","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_083,9,5073737,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His606Asn/c.1816C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),22721,257,23074,"0,0111380775",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,99",Deleterious,1,Damaging,"29,84","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_084,9,5073737,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His606Asn/c.1816C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),24926,293,25313,"0,01157508",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,99",Deleterious,1,Damaging,"29,63","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_085,9,5073737,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His606Asn/c.1816C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),32160,384,32701,"0,0117427602",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,99",Deleterious,1,Damaging,"29,61","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_086,9,5073737,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His606Asn/c.1816C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),28830,318,29284,"0,0108591722",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,99",Deleterious,1,Damaging,"29,68","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_087,9,5073737,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His606Asn/c.1816C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),25473,342,25922,"0,0131934264",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,99",Deleterious,1,Damaging,"29,58","14,62"
"low bq, low freq, many artifacts",UPN2_088,9,5073737,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His606Asn/c.1816C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),22410,306,22820,"0,0134092901",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,99",Deleterious,1,Damaging,"29,42","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_047,9,5073739,C,A,missense_variant(MODERATE|MISSENSE|caC/caA|p.His606Gln/c.1818C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),5312,55,5393,"0,0101984053",0,0,0,0,1,0,0,0,1,"0,0116",NO,COSM29116,haematopoietic_and_lymphoid_tissue,1,NO,rs145561071,NO,"2,47E-005",NO,NO,"-6,61",Deleterious,1,Damaging,"29,4","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_059,9,5073739,C,A,missense_variant(MODERATE|MISSENSE|caC/caA|p.His606Gln/c.1818C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),2030,21,2069,"0,0101498308",0,0,0,0,1,0,0,0,1,"0,0116",NO,COSM29116,haematopoietic_and_lymphoid_tissue,1,NO,rs145561071,NO,"2,47E-005",NO,NO,"-6,61",Deleterious,1,Damaging,"28,06",14
"low bq, low freq, many artifacts, many samples",UPN2_061,9,5073739,C,A,missense_variant(MODERATE|MISSENSE|caC/caA|p.His606Gln/c.1818C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),16613,172,16920,"0,0101654846",0,0,0,0,1,0,0,0,1,"0,0116",NO,COSM29116,haematopoietic_and_lymphoid_tissue,1,NO,rs145561071,NO,"2,47E-005",NO,NO,"-6,61",Deleterious,1,Damaging,"28,37","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_063,9,5073739,C,A,missense_variant(MODERATE|MISSENSE|caC/caA|p.His606Gln/c.1818C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),13010,135,13281,"0,0101648972",0,0,0,0,1,0,0,0,1,"0,0116",NO,COSM29116,haematopoietic_and_lymphoid_tissue,1,NO,rs145561071,NO,"2,47E-005",NO,NO,"-6,61",Deleterious,1,Damaging,"28,51","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_064,9,5073739,C,A,missense_variant(MODERATE|MISSENSE|caC/caA|p.His606Gln/c.1818C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),2606,37,2663,"0,0138941044",0,0,0,0,1,0,0,0,1,"0,0116",NO,COSM29116,haematopoietic_and_lymphoid_tissue,1,NO,rs145561071,NO,"2,47E-005",NO,NO,"-6,61",Deleterious,1,Damaging,"28,33","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_065,9,5073739,C,A,missense_variant(MODERATE|MISSENSE|caC/caA|p.His606Gln/c.1818C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),7420,83,7592,"0,0109325606",0,0,0,0,1,0,0,0,1,"0,0116",NO,COSM29116,haematopoietic_and_lymphoid_tissue,1,NO,rs145561071,NO,"2,47E-005",NO,NO,"-6,61",Deleterious,1,Damaging,"28,2","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_066,9,5073739,C,A,missense_variant(MODERATE|MISSENSE|caC/caA|p.His606Gln/c.1818C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),31360,373,32043,"0,0116406079",0,0,0,0,1,0,0,0,1,"0,0116",NO,COSM29116,haematopoietic_and_lymphoid_tissue,1,NO,rs145561071,NO,"2,47E-005",NO,NO,"-6,61",Deleterious,1,Damaging,"28,29","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_067,9,5073739,C,A,missense_variant(MODERATE|MISSENSE|caC/caA|p.His606Gln/c.1818C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),34956,385,35724,"0,0107770686",0,0,0,0,1,0,0,0,1,"0,0116",NO,COSM29116,haematopoietic_and_lymphoid_tissue,1,NO,rs145561071,NO,"2,47E-005",NO,NO,"-6,61",Deleterious,1,Damaging,"28,27","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_068,9,5073739,C,A,missense_variant(MODERATE|MISSENSE|caC/caA|p.His606Gln/c.1818C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),22981,239,23468,"0,0101840804",0,0,0,0,1,0,0,0,1,"0,0116",NO,COSM29116,haematopoietic_and_lymphoid_tissue,1,NO,rs145561071,NO,"2,47E-005",NO,NO,"-6,61",Deleterious,1,Damaging,"28,5","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_070,9,5073739,C,A,missense_variant(MODERATE|MISSENSE|caC/caA|p.His606Gln/c.1818C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),14729,156,15026,"0,0103820045",0,0,0,0,1,0,0,0,1,"0,0116",NO,COSM29116,haematopoietic_and_lymphoid_tissue,1,NO,rs145561071,NO,"2,47E-005",NO,NO,"-6,61",Deleterious,1,Damaging,"28,47","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_071,9,5073739,C,A,missense_variant(MODERATE|MISSENSE|caC/caA|p.His606Gln/c.1818C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),7953,96,8108,"0,0118401579",0,0,0,0,1,0,0,0,1,"0,0116",NO,COSM29116,haematopoietic_and_lymphoid_tissue,1,NO,rs145561071,NO,"2,47E-005",NO,NO,"-6,61",Deleterious,1,Damaging,"28,25","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_072,9,5073739,C,A,missense_variant(MODERATE|MISSENSE|caC/caA|p.His606Gln/c.1818C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),6786,74,6917,"0,0106982796",0,0,0,0,1,0,0,0,1,"0,0116",NO,COSM29116,haematopoietic_and_lymphoid_tissue,1,NO,rs145561071,NO,"2,47E-005",NO,NO,"-6,61",Deleterious,1,Damaging,"28,5","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_073,9,5073739,C,A,missense_variant(MODERATE|MISSENSE|caC/caA|p.His606Gln/c.1818C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),5882,66,6036,"0,0109343936",0,0,0,0,1,0,0,0,1,"0,0116",NO,COSM29116,haematopoietic_and_lymphoid_tissue,1,NO,rs145561071,NO,"2,47E-005",NO,NO,"-6,61",Deleterious,1,Damaging,"28,37","14,2"
"low bq, low freq, many artifacts, many samples",UPN2_074,9,5073739,C,A,missense_variant(MODERATE|MISSENSE|caC/caA|p.His606Gln/c.1818C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),13551,159,13828,"0,011498409",0,0,0,0,1,0,0,0,1,"0,0116",NO,COSM29116,haematopoietic_and_lymphoid_tissue,1,NO,rs145561071,NO,"2,47E-005",NO,NO,"-6,61",Deleterious,1,Damaging,"28,33","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_075,9,5073739,C,A,missense_variant(MODERATE|MISSENSE|caC/caA|p.His606Gln/c.1818C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),16816,193,17196,"0,0112235404",0,0,0,0,1,0,0,0,1,"0,0116",NO,COSM29116,haematopoietic_and_lymphoid_tissue,1,NO,rs145561071,NO,"2,47E-005",NO,NO,"-6,61",Deleterious,1,Damaging,"28,16","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_079,9,5073739,C,A,missense_variant(MODERATE|MISSENSE|caC/caA|p.His606Gln/c.1818C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),10863,116,11089,"0,010460817",0,0,0,0,1,0,0,0,1,"0,0116",NO,COSM29116,haematopoietic_and_lymphoid_tissue,1,NO,rs145561071,NO,"2,47E-005",NO,NO,"-6,61",Deleterious,1,Damaging,"28,45",14
"low bq, low freq, many artifacts, many samples",UPN2_081,9,5073739,C,A,missense_variant(MODERATE|MISSENSE|caC/caA|p.His606Gln/c.1818C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),4297,47,4381,"0,0107281443",0,0,0,0,1,0,0,0,1,"0,0116",NO,COSM29116,haematopoietic_and_lymphoid_tissue,1,NO,rs145561071,NO,"2,47E-005",NO,NO,"-6,61",Deleterious,1,Damaging,"28,03","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_082,9,5073739,C,A,missense_variant(MODERATE|MISSENSE|caC/caA|p.His606Gln/c.1818C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),24113,297,24676,"0,0120359864",0,0,0,0,1,0,0,0,1,"0,0116",NO,COSM29116,haematopoietic_and_lymphoid_tissue,1,NO,rs145561071,NO,"2,47E-005",NO,NO,"-6,61",Deleterious,1,Damaging,"28,26","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_084,9,5073739,C,A,missense_variant(MODERATE|MISSENSE|caC/caA|p.His606Gln/c.1818C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),24836,263,25331,"0,0103825352",0,0,0,0,1,0,0,0,1,"0,0116",NO,COSM29116,haematopoietic_and_lymphoid_tissue,1,NO,rs145561071,NO,"2,47E-005",NO,NO,"-6,61",Deleterious,1,Damaging,"28,49","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_087,9,5073739,C,A,missense_variant(MODERATE|MISSENSE|caC/caA|p.His606Gln/c.1818C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),25437,265,25931,"0,0102194285",0,0,0,0,1,0,0,0,1,"0,0116",NO,COSM29116,haematopoietic_and_lymphoid_tissue,1,NO,rs145561071,NO,"2,47E-005",NO,NO,"-6,61",Deleterious,1,Damaging,"28,34","14,65"
"low bq, low freq, many artifacts",UPN2_088,9,5073739,C,A,missense_variant(MODERATE|MISSENSE|caC/caA|p.His606Gln/c.1818C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),22376,230,22832,"0,0100735809",0,0,0,0,1,0,0,0,1,"0,0116",NO,COSM29116,haematopoietic_and_lymphoid_tissue,1,NO,rs145561071,NO,"2,47E-005",NO,NO,"-6,61",Deleterious,1,Damaging,"28,19","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_044,9,5073740,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys607*/c.1819A>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),2804,30,2844,"0,0105485232",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,43","18,3"
"low bq, low freq, many artifacts, many samples",UPN2_047,9,5073740,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys607*/c.1819A>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),5287,54,5397,"0,0100055586",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,48","20,22"
"low bq, low freq, many artifacts, many samples",UPN2_002,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),16187,176,16401,"0,010731053",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"31,42","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_042,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),6642,79,6786,"0,0116416151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"29,64","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_043,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),11638,138,11834,"0,0116613149",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"29,52","14,13"
"low bq, low freq, many artifacts, many samples",UPN2_044,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),2795,35,2853,"0,0122677883",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"29,59",14
"low bq, low freq, many artifacts, many samples",UPN2_047,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),5334,64,5412,"0,0118255728",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"29,45",14
"low bq, low freq, many artifacts, many samples",UPN2_049,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),4913,50,4983,"0,010034116",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"29,73","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_050,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),13212,160,13429,"0,0119145134",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"29,61","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_051,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),17444,199,17712,"0,0112353207",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"29,51","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_052,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),13993,149,14213,"0,0104833603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"29,72","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_053,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),22057,229,22375,"0,0102346369",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"29,65","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_007,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),39015,423,39572,"0,0106893763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"31,03","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_009,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),39278,460,39863,"0,0115395229",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"31,23","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_010,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),31533,331,31955,"0,0103583164",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"31,21","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_011,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),36515,424,37013,"0,0114554346",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"31,08","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_055,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),17793,195,18080,"0,0107853982",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"29,68","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_057,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),21625,233,21956,"0,0106121334",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"29,53","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_058,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),22353,280,22735,"0,0123158126",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"29,57","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_059,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),2026,37,2081,"0,0177799135",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"28,76","14,19"
"low bq, low freq, many artifacts, many samples",UPN2_012,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),13357,150,13531,"0,0110856552",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"31,14","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_060,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),15339,238,15681,"0,0151776035",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"28,82","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_013,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),10499,112,10636,"0,0105302745",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"31,09","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_061,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),16641,234,16981,"0,0137801072",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"28,82","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_062,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),11700,168,11955,"0,0140526976",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"28,99","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_063,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),13061,169,13318,"0,012689593",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"28,83","14,18"
"low bq, low freq, many artifacts, many samples",UPN2_064,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),2615,44,2675,"0,0164485981",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"28,86","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_065,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),7452,107,7619,"0,0140438378",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"28,6","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_066,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),31437,491,32156,"0,0152693121",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"28,63","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_067,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),35048,579,35863,"0,0161447732",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"28,61","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_068,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),23067,339,23556,"0,0143912379",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"28,96","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_069,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),20807,307,21239,"0,0144545412",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"28,8","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_070,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),14779,228,15080,"0,0151193634",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"28,98","14,15"
"low bq, low freq, many artifacts, many samples",UPN2_071,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),7973,133,8149,"0,016321021",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"28,82","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_072,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),6801,104,6938,"0,0149899106",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"28,84","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_073,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),5925,97,6058,"0,0160118851",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"28,83","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_074,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),13574,214,13898,"0,015397899",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"28,69","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_075,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),16884,274,17270,"0,015865663",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"28,56","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_076,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),18735,294,19136,"0,0153637124",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"29,07","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_077,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),22564,331,23029,"0,0143731816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"28,88","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_078,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),15429,226,15742,"0,0143564985",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"29,09","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_079,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),10917,154,11137,"0,0138277813",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"28,81","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_080,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),12971,194,13268,"0,0146216461",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"28,73","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_081,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),4315,61,4399,"0,0138667879",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"28,58","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_082,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),24228,381,24774,"0,0153790264",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"28,65","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_083,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),22729,315,23180,"0,0135893011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"28,95","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_084,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),24946,342,25412,"0,0134582087",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"28,86","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_085,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),32146,501,32851,"0,0152506773",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"28,78","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_086,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),28796,427,29411,"0,0145183775",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"28,82","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_087,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),25478,411,26033,"0,0157876541",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"28,72","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_088,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),22422,346,22915,"0,0150992799",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"28,61","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_097,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),11231,119,11393,"0,0104450101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"29,9","14,12"
"low bq, low freq, many artifacts, many samples",UPN2_099,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),6520,74,6621,"0,0111765594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"29,84","14,66"
"low bq, low freq, many artifacts",UPN2_100,9,5073743,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His608Asn/c.1822C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),10515,112,10672,"0,0104947526",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,45",Deleterious,8,Damaging,"29,71","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_059,9,5073748,G,T,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu609Phe/c.1827G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),2057,27,2089,"0,0129248444",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,4,Damaging,"29,14","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_060,9,5073748,G,T,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu609Phe/c.1827G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),15541,189,15755,"0,0119961917",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,4,Damaging,"29,5","16,04"
"low bq, low freq, many artifacts, many samples",UPN2_061,9,5073748,G,T,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu609Phe/c.1827G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),16834,191,17053,"0,0112003753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,4,Damaging,"29,45","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_063,9,5073748,G,T,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu609Phe/c.1827G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),13192,154,13378,"0,0115114367",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,4,Damaging,"29,54","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_065,9,5073748,G,T,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu609Phe/c.1827G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),7537,110,7656,"0,0143678161",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,4,Damaging,"29,27","15,75"
"low bq, low freq, many artifacts, many samples",UPN2_066,9,5073748,G,T,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu609Phe/c.1827G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),31837,377,32282,"0,0116783347",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,4,Damaging,"29,33","15,68"
"low bq, low freq, many artifacts, many samples",UPN2_067,9,5073748,G,T,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu609Phe/c.1827G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),35533,421,36016,"0,0116892492",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,4,Damaging,"29,32","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_068,9,5073748,G,T,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu609Phe/c.1827G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),23366,254,23660,"0,0107354184",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,4,Damaging,"29,49","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_069,9,5073748,G,T,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu609Phe/c.1827G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),20996,280,21327,"0,0131288976",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,4,Damaging,"29,4","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_070,9,5073748,G,T,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu609Phe/c.1827G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),14964,154,15141,"0,0101710587",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,4,Damaging,"29,47","15,17"
"low bq, low freq, many artifacts, many samples",UPN2_071,9,5073748,G,T,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu609Phe/c.1827G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),8094,84,8183,"0,0102651839",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,4,Damaging,"29,34","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_072,9,5073748,G,T,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu609Phe/c.1827G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),6871,73,6954,"0,0104975554",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,4,Damaging,"29,4","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_073,9,5073748,G,T,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu609Phe/c.1827G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),5995,77,6089,"0,0126457546",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,4,Damaging,"29,3","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_074,9,5073748,G,T,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu609Phe/c.1827G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),13765,176,13957,"0,0126101598",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,4,Damaging,"29,36","16,35"
"low bq, low freq, many artifacts, many samples",UPN2_075,9,5073748,G,T,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu609Phe/c.1827G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),17100,211,17330,"0,0121754183",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,4,Damaging,"29,27","15,31"
"low bq, low freq, many artifacts, many samples",UPN2_076,9,5073748,G,T,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu609Phe/c.1827G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),18962,209,19207,"0,0108814495",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,4,Damaging,"29,52","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_077,9,5073748,G,T,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu609Phe/c.1827G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),22772,273,23110,"0,0118130679",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,4,Damaging,"29,53","15,74"
"low bq, low freq, many artifacts, many samples",UPN2_078,9,5073748,G,T,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu609Phe/c.1827G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),15589,184,15803,"0,0116433589",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,4,Damaging,"29,6","16,09"
"low bq, low freq, many artifacts, many samples",UPN2_079,9,5073748,G,T,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu609Phe/c.1827G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),11046,112,11183,"0,0100152016",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,4,Damaging,"29,44","16,41"
"low bq, low freq, many artifacts, many samples",UPN2_080,9,5073748,G,T,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu609Phe/c.1827G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),13152,145,13317,"0,0108883382",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,4,Damaging,"29,35","15,94"
"low bq, low freq, many artifacts, many samples",UPN2_081,9,5073748,G,T,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu609Phe/c.1827G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),4352,55,4417,"0,0124518904",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,4,Damaging,"29,2","16,11"
"low bq, low freq, many artifacts, many samples",UPN2_082,9,5073748,G,T,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu609Phe/c.1827G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),24535,293,24879,"0,0117770007",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,4,Damaging,"29,3","15,64"
"low bq, low freq, many artifacts, many samples",UPN2_083,9,5073748,G,T,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu609Phe/c.1827G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),22974,248,23283,"0,0106515483",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,4,Damaging,"29,53","15,5"
"low bq, low freq, many artifacts, many samples",UPN2_084,9,5073748,G,T,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu609Phe/c.1827G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),25178,287,25515,"0,0112482853",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,4,Damaging,"29,41","15,74"
"low bq, low freq, many artifacts, many samples",UPN2_085,9,5073748,G,T,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu609Phe/c.1827G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),32582,364,33011,"0,0110266275",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,4,Damaging,"29,47","15,65"
"low bq, low freq, many artifacts",UPN2_086,9,5073748,G,T,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu609Phe/c.1827G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),29131,310,29504,"0,0105070499",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,4,Damaging,"29,49","15,37"
"low bq, low freq, many artifacts, many samples",UPN2_059,9,5073749,G,T,missense_variant(MODERATE|MISSENSE|Gtt/Ttt|p.Val610Phe/c.1828G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),2062,29,2092,"0,0138623327",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,18",Deleterious,2,Damaging,"29,59","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_060,9,5073749,G,T,missense_variant(MODERATE|MISSENSE|Gtt/Ttt|p.Val610Phe/c.1828G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),15564,175,15763,"0,0111019476",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,18",Deleterious,2,Damaging,"29,75","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_061,9,5073749,G,T,missense_variant(MODERATE|MISSENSE|Gtt/Ttt|p.Val610Phe/c.1828G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),16870,174,17062,"0,010198101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,18",Deleterious,2,Damaging,"29,74","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_062,9,5073749,G,T,missense_variant(MODERATE|MISSENSE|Gtt/Ttt|p.Val610Phe/c.1828G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),11842,134,12002,"0,0111648059",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,18",Deleterious,2,Damaging,"30,02","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_063,9,5073749,G,T,missense_variant(MODERATE|MISSENSE|Gtt/Ttt|p.Val610Phe/c.1828G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),13228,143,13383,"0,0106851976",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,18",Deleterious,2,Damaging,"29,9","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_065,9,5073749,G,T,missense_variant(MODERATE|MISSENSE|Gtt/Ttt|p.Val610Phe/c.1828G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),7574,84,7661,"0,010964626",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,18",Deleterious,2,Damaging,"29,61","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_066,9,5073749,G,T,missense_variant(MODERATE|MISSENSE|Gtt/Ttt|p.Val610Phe/c.1828G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),31920,345,32309,"0,0106781392",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,18",Deleterious,2,Damaging,"29,64","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_067,9,5073749,G,T,missense_variant(MODERATE|MISSENSE|Gtt/Ttt|p.Val610Phe/c.1828G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),35625,390,36049,"0,010818608",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,18",Deleterious,2,Damaging,"29,67","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_068,9,5073749,G,T,missense_variant(MODERATE|MISSENSE|Gtt/Ttt|p.Val610Phe/c.1828G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),23396,264,23678,"0,0111495903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,18",Deleterious,2,Damaging,"29,87","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_069,9,5073749,G,T,missense_variant(MODERATE|MISSENSE|Gtt/Ttt|p.Val610Phe/c.1828G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),21087,216,21336,"0,0101237345",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,18",Deleterious,2,Damaging,"29,82","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_071,9,5073749,G,T,missense_variant(MODERATE|MISSENSE|Gtt/Ttt|p.Val610Phe/c.1828G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),8093,87,8189,"0,0106240078",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,18",Deleterious,2,Damaging,"29,74","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_072,9,5073749,G,T,missense_variant(MODERATE|MISSENSE|Gtt/Ttt|p.Val610Phe/c.1828G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),6873,71,6959,"0,0102026153",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,18",Deleterious,2,Damaging,"29,88","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_073,9,5073749,G,T,missense_variant(MODERATE|MISSENSE|Gtt/Ttt|p.Val610Phe/c.1828G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),6024,65,6096,"0,0106627297",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,18",Deleterious,2,Damaging,"29,91","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_074,9,5073749,G,T,missense_variant(MODERATE|MISSENSE|Gtt/Ttt|p.Val610Phe/c.1828G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),13806,144,13971,"0,0103070646",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,18",Deleterious,2,Damaging,"29,71","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_075,9,5073749,G,T,missense_variant(MODERATE|MISSENSE|Gtt/Ttt|p.Val610Phe/c.1828G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),17145,182,17346,"0,0104923325",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,18",Deleterious,2,Damaging,"29,61","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_076,9,5073749,G,T,missense_variant(MODERATE|MISSENSE|Gtt/Ttt|p.Val610Phe/c.1828G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),18990,207,19224,"0,0107677903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,18",Deleterious,2,Damaging,"29,89","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_077,9,5073749,G,T,missense_variant(MODERATE|MISSENSE|Gtt/Ttt|p.Val610Phe/c.1828G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),22854,240,23122,"0,0103797249",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,18",Deleterious,2,Damaging,"29,87","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_078,9,5073749,G,T,missense_variant(MODERATE|MISSENSE|Gtt/Ttt|p.Val610Phe/c.1828G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),15641,160,15815,"0,0101169776",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,18",Deleterious,2,Damaging,"29,98","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_080,9,5073749,G,T,missense_variant(MODERATE|MISSENSE|Gtt/Ttt|p.Val610Phe/c.1828G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),13174,135,13330,"0,0101275319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,18",Deleterious,2,Damaging,"29,74","14,1"
"low bq, low freq, many artifacts, many samples",UPN2_081,9,5073749,G,T,missense_variant(MODERATE|MISSENSE|Gtt/Ttt|p.Val610Phe/c.1828G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),4369,52,4421,"0,0117620448",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,18",Deleterious,2,Damaging,"29,6","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_082,9,5073749,G,T,missense_variant(MODERATE|MISSENSE|Gtt/Ttt|p.Val610Phe/c.1828G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),24533,292,24897,"0,0117283207",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,18",Deleterious,2,Damaging,"29,68","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_083,9,5073749,G,T,missense_variant(MODERATE|MISSENSE|Gtt/Ttt|p.Val610Phe/c.1828G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),23024,260,23300,"0,0111587983",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,18",Deleterious,2,Damaging,"29,96","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_084,9,5073749,G,T,missense_variant(MODERATE|MISSENSE|Gtt/Ttt|p.Val610Phe/c.1828G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),25230,265,25537,"0,0103770999",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,18",Deleterious,2,Damaging,"29,8","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_085,9,5073749,G,T,missense_variant(MODERATE|MISSENSE|Gtt/Ttt|p.Val610Phe/c.1828G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),32594,393,33037,"0,0118957532",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,18",Deleterious,2,Damaging,"29,82","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_086,9,5073749,G,T,missense_variant(MODERATE|MISSENSE|Gtt/Ttt|p.Val610Phe/c.1828G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),29159,331,29525,"0,0112108383",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,18",Deleterious,2,Damaging,"29,89","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_087,9,5073749,G,T,missense_variant(MODERATE|MISSENSE|Gtt/Ttt|p.Val610Phe/c.1828G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),25865,278,26176,"0,0106204156",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,18",Deleterious,2,Damaging,"29,66","15,04"
"low bq, low freq, many artifacts",UPN2_088,9,5073749,G,T,missense_variant(MODERATE|MISSENSE|Gtt/Ttt|p.Val610Phe/c.1828G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),22750,254,23026,"0,0110310084",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,18",Deleterious,2,Damaging,"29,69","15,17"
"low bq, low freq, many artifacts",UPN2_064,9,5073755,A,T,missense_variant(MODERATE|MISSENSE|Aat/Tat|p.Asn612Tyr/c.1834A>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),2652,29,2691,"0,010776663",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,"0,03",Damaging,"32,56","22,55"
"low bq, low freq, many artifacts",UPN2_059,9,5073761,G,T,stop_gained(HIGH|NONSENSE|Gga/Tga|p.Gly614*/c.1840G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),2073,21,2097,"0,0100143062",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,15",14
"low bq, low freq, many artifacts, many samples",UPN2_047,9,5073762,G,T,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly614Val/c.1841G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),5353,59,5426,"0,0108735717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,31",Deleterious,0,Damaging,"30,34","15,31"
"low bq, low freq, many artifacts, many samples",UPN2_059,9,5073762,G,T,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly614Val/c.1841G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),2050,37,2094,"0,017669532",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,31",Deleterious,0,Damaging,"28,71","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_060,9,5073762,G,T,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly614Val/c.1841G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),15535,202,15759,"0,0128180722",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,31",Deleterious,0,Damaging,"28,84","15,71"
"low bq, low freq, many artifacts, many samples",UPN2_061,9,5073762,G,T,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly614Val/c.1841G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),16811,219,17059,"0,0128377982",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,31",Deleterious,0,Damaging,"29,03","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_062,9,5073762,G,T,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly614Val/c.1841G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),11797,166,11991,"0,0138437161",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,31",Deleterious,0,Damaging,"29,14","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_063,9,5073762,G,T,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly614Val/c.1841G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),13183,160,13376,"0,0119617225",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,31",Deleterious,0,Damaging,"29,1","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_064,9,5073762,G,T,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly614Val/c.1841G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),2650,35,2687,"0,0130256792",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,31",Deleterious,0,Damaging,"28,81","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_065,9,5073762,G,T,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly614Val/c.1841G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),7537,113,7662,"0,0147481075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,31",Deleterious,0,Damaging,"28,76","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_066,9,5073762,G,T,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly614Val/c.1841G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),31776,457,32306,"0,0141459791",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,31",Deleterious,0,Damaging,"28,91","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_067,9,5073762,G,T,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly614Val/c.1841G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),35463,500,36033,"0,0138761691",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,31",Deleterious,0,Damaging,"28,81","15,37"
"low bq, low freq, many artifacts, many samples",UPN2_068,9,5073762,G,T,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly614Val/c.1841G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),23357,279,23678,"0,0117830898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,31",Deleterious,0,Damaging,"29,08","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_069,9,5073762,G,T,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly614Val/c.1841G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),20997,283,21333,"0,0132658323",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,31",Deleterious,0,Damaging,"28,95","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_070,9,5073762,G,T,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly614Val/c.1841G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),14922,200,15146,"0,0132048065",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,31",Deleterious,0,Damaging,"29,1","15,72"
"low bq, low freq, many artifacts, many samples",UPN2_071,9,5073762,G,T,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly614Val/c.1841G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),8061,103,8187,"0,012580921",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,31",Deleterious,0,Damaging,"28,89","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_072,9,5073762,G,T,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly614Val/c.1841G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),6876,77,6965,"0,0110552764",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,31",Deleterious,0,Damaging,"28,98","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_073,9,5073762,G,T,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly614Val/c.1841G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),5979,78,6086,"0,0128162997",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,31",Deleterious,0,Damaging,"28,96",14
"low bq, low freq, many artifacts, many samples",UPN2_074,9,5073762,G,T,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly614Val/c.1841G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),13744,198,13973,"0,0141701854",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,31",Deleterious,0,Damaging,"28,89","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_075,9,5073762,G,T,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly614Val/c.1841G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),17009,284,17347,"0,0163717069",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,31",Deleterious,0,Damaging,"28,84","16,41"
"low bq, low freq, many artifacts, many samples",UPN2_076,9,5073762,G,T,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly614Val/c.1841G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),18935,231,19215,"0,0120218579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,31",Deleterious,0,Damaging,"29,17","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_077,9,5073762,G,T,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly614Val/c.1841G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),22785,294,23124,"0,0127140633",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,31",Deleterious,0,Damaging,"29,12","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_078,9,5073762,G,T,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly614Val/c.1841G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),15599,191,15818,"0,0120748514",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,31",Deleterious,0,Damaging,"29,12","15,3"
"low bq, low freq, many artifacts, many samples",UPN2_079,9,5073762,G,T,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly614Val/c.1841G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),11014,141,11176,"0,0126163207",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,31",Deleterious,0,Damaging,"28,97","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_080,9,5073762,G,T,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly614Val/c.1841G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),13112,181,13335,"0,0135733033",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,31",Deleterious,0,Damaging,"28,9","16,02"
"low bq, low freq, many artifacts, many samples",UPN2_081,9,5073762,G,T,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly614Val/c.1841G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),4350,58,4422,"0,013116237",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,31",Deleterious,0,Damaging,"28,67","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_082,9,5073762,G,T,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly614Val/c.1841G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),24502,320,24888,"0,0128576021",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,31",Deleterious,0,Damaging,"28,74","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_083,9,5073762,G,T,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly614Val/c.1841G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),22995,255,23295,"0,0109465551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,31",Deleterious,0,Damaging,"29,06","14,2"
"low bq, low freq, many artifacts, many samples",UPN2_084,9,5073762,G,T,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly614Val/c.1841G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),25145,334,25536,"0,0130795739",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,31",Deleterious,0,Damaging,"29,06","15,78"
"low bq, low freq, many artifacts, many samples",UPN2_085,9,5073762,G,T,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly614Val/c.1841G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),32555,408,33036,"0,0123501635",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,31",Deleterious,0,Damaging,"28,98","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_086,9,5073762,G,T,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly614Val/c.1841G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),29143,324,29533,"0,0109707785",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,31",Deleterious,0,Damaging,"29,05","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_087,9,5073762,G,T,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly614Val/c.1841G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),25758,348,26175,"0,0132951289",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,31",Deleterious,0,Damaging,"28,91","15,47"
"low bq, low freq, many artifacts",UPN2_088,9,5073762,G,T,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly614Val/c.1841G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),22668,305,23012,"0,0132539545",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,31",Deleterious,0,Damaging,"28,82","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_059,9,5073764,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val615Leu/c.1843G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),2067,27,2094,"0,0128939828",0,0,0,0,1,0,0,0,1,NO,NO,COSM4391514,haematopoietic_and_lymphoid_tissue,130,NO,NO,NO,NO,NO,NO,"-2,31",Neutral,2,Damaging,"31,15","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_061,9,5073764,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val615Leu/c.1843G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),16862,175,17058,"0,010259116",0,0,0,0,1,0,0,0,1,NO,NO,COSM4391514,haematopoietic_and_lymphoid_tissue,130,NO,NO,NO,NO,NO,NO,"-2,31",Neutral,2,Damaging,"31,4","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_047,9,5073768,G,T,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys616Phe/c.1847G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),5346,75,5429,"0,0138146988",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,46",Deleterious,11,Damaging,"32,44",14
"low bq, low freq, many artifacts, many samples",UPN2_051,9,5073768,G,T,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys616Phe/c.1847G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),17546,178,17766,"0,0100191377",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,46",Deleterious,11,Damaging,"32,53","18,06"
"low bq, low freq, many artifacts, many samples",UPN2_059,9,5073768,G,T,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys616Phe/c.1847G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),2067,22,2093,"0,0105112279",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,46",Deleterious,11,Damaging,"31,39",14
"low bq, low freq, many artifacts, many samples",UPN2_064,9,5073768,G,T,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys616Phe/c.1847G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),2652,30,2684,"0,0111773472",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,46",Deleterious,11,Damaging,"31,42",14
"low bq, low freq, many artifacts, many samples",UPN2_066,9,5073768,G,T,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys616Phe/c.1847G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),31860,350,32283,"0,0108416194",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,46",Deleterious,11,Damaging,"31,4","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_067,9,5073768,G,T,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys616Phe/c.1847G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),35561,380,36009,"0,0105529173",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,46",Deleterious,11,Damaging,"31,44","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_071,9,5073768,G,T,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys616Phe/c.1847G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),8070,84,8177,"0,0102727162",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,46",Deleterious,11,Damaging,"31,51","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_074,9,5073768,G,T,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys616Phe/c.1847G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),13783,153,13965,"0,0109559613",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,46",Deleterious,11,Damaging,"31,37","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_075,9,5073768,G,T,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys616Phe/c.1847G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),17119,189,17340,"0,010899654",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,46",Deleterious,11,Damaging,"31,39","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_077,9,5073768,G,T,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys616Phe/c.1847G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),22812,232,23110,"0,0100389442",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,46",Deleterious,11,Damaging,"31,62","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_079,9,5073768,G,T,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys616Phe/c.1847G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),11022,121,11174,"0,0108287095",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,46",Deleterious,11,Damaging,"31,54","15,53"
"low bq, low freq, many artifacts, many samples",UPN2_080,9,5073768,G,T,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys616Phe/c.1847G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),13169,142,13335,"0,0106486689",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,46",Deleterious,11,Damaging,"31,44","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_084,9,5073768,G,T,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys616Phe/c.1847G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),25201,258,25519,"0,010110114",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,46",Deleterious,11,Damaging,"31,58","14,74"
"low bq, low freq, many artifacts",UPN2_085,9,5073768,G,T,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys616Phe/c.1847G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),32596,339,33005,"0,010271171",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,46",Deleterious,11,Damaging,"31,52","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_049,9,5073770,G,T,missense_variant(MODERATE|MISSENSE|Gtc/Ttc|p.Val617Phe/c.1849G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),4907,76,5000,"0,0152",0,0,0,0,1,0,0,0,1,"0,0233",NO,COSM12600,central_nervous_system. haematopoietic_and_lymphoid_tissue. lung,1. 37620. 3,NO,rs77375493,YES,"0,0006919",NO,NO,"-3,86",Deleterious,2,Damaging,"32,71","22,87"
"low bq, low freq, many artifacts, many samples",UPN2_059,9,5073770,G,T,missense_variant(MODERATE|MISSENSE|Gtc/Ttc|p.Val617Phe/c.1849G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),2062,28,2091,"0,0133907221",0,0,0,0,1,0,0,0,1,"0,0233",NO,COSM12600,central_nervous_system. haematopoietic_and_lymphoid_tissue. lung,1. 37620. 3,NO,rs77375493,YES,"0,0006919",NO,NO,"-3,86",Deleterious,2,Damaging,"30,96","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_064,9,5073770,G,T,missense_variant(MODERATE|MISSENSE|Gtc/Ttc|p.Val617Phe/c.1849G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),2646,27,2684,"0,0100596125",0,0,0,0,1,0,0,0,1,"0,0233",NO,COSM12600,central_nervous_system. haematopoietic_and_lymphoid_tissue. lung,1. 37620. 3,NO,rs77375493,YES,"0,0006919",NO,NO,"-3,86",Deleterious,2,Damaging,"31,11",14
"low bq, low freq, many artifacts, many samples",UPN2_066,9,5073770,G,T,missense_variant(MODERATE|MISSENSE|Gtc/Ttc|p.Val617Phe/c.1849G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),31914,331,32279,"0,0102543449",0,0,0,0,1,0,0,0,1,"0,0233",NO,COSM12600,central_nervous_system. haematopoietic_and_lymphoid_tissue. lung,1. 37620. 3,NO,rs77375493,YES,"0,0006919",NO,NO,"-3,86",Deleterious,2,Damaging,"31,1","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_068,9,5073770,G,T,missense_variant(MODERATE|MISSENSE|Gtc/Ttc|p.Val617Phe/c.1849G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),23392,246,23661,"0,0103968556",0,0,0,0,1,0,0,0,1,"0,0233",NO,COSM12600,central_nervous_system. haematopoietic_and_lymphoid_tissue. lung,1. 37620. 3,NO,rs77375493,YES,"0,0006919",NO,NO,"-3,86",Deleterious,2,Damaging,"31,3","15,55"
"low bq, low freq, many artifacts, many samples",UPN2_069,9,5073770,G,T,missense_variant(MODERATE|MISSENSE|Gtc/Ttc|p.Val617Phe/c.1849G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),21035,247,21321,"0,0115848225",0,0,0,0,1,0,0,0,1,"0,0233",NO,COSM12600,central_nervous_system. haematopoietic_and_lymphoid_tissue. lung,1. 37620. 3,NO,rs77375493,YES,"0,0006919",NO,NO,"-3,86",Deleterious,2,Damaging,"31,12","17,55"
"low bq, low freq, many artifacts, many samples",UPN2_070,9,5073770,G,T,missense_variant(MODERATE|MISSENSE|Gtc/Ttc|p.Val617Phe/c.1849G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),14952,164,15143,"0,0108300865",0,0,0,0,1,0,0,0,1,"0,0233",NO,COSM12600,central_nervous_system. haematopoietic_and_lymphoid_tissue. lung,1. 37620. 3,NO,rs77375493,YES,"0,0006919",NO,NO,"-3,86",Deleterious,2,Damaging,"31,25","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_072,9,5073770,G,T,missense_variant(MODERATE|MISSENSE|Gtc/Ttc|p.Val617Phe/c.1849G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),6876,70,6962,"0,010054582",0,0,0,0,1,0,0,0,1,"0,0233",NO,COSM12600,central_nervous_system. haematopoietic_and_lymphoid_tissue. lung,1. 37620. 3,NO,rs77375493,YES,"0,0006919",NO,NO,"-3,86",Deleterious,2,Damaging,"31,22","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_073,9,5073770,G,T,missense_variant(MODERATE|MISSENSE|Gtc/Ttc|p.Val617Phe/c.1849G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),6002,61,6082,"0,0100295955",0,0,0,0,1,0,0,0,1,"0,0233",NO,COSM12600,central_nervous_system. haematopoietic_and_lymphoid_tissue. lung,1. 37620. 3,NO,rs77375493,YES,"0,0006919",NO,NO,"-3,86",Deleterious,2,Damaging,"31,24","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_074,9,5073770,G,T,missense_variant(MODERATE|MISSENSE|Gtc/Ttc|p.Val617Phe/c.1849G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),13781,153,13961,"0,0109591004",0,0,0,0,1,0,0,0,1,"0,0233",NO,COSM12600,central_nervous_system. haematopoietic_and_lymphoid_tissue. lung,1. 37620. 3,NO,rs77375493,YES,"0,0006919",NO,NO,"-3,86",Deleterious,2,Damaging,"31,12","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_075,9,5073770,G,T,missense_variant(MODERATE|MISSENSE|Gtc/Ttc|p.Val617Phe/c.1849G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),17098,211,17333,"0,012173311",0,0,0,0,1,0,0,0,1,"0,0233",NO,COSM12600,central_nervous_system. haematopoietic_and_lymphoid_tissue. lung,1. 37620. 3,NO,rs77375493,YES,"0,0006919",NO,NO,"-3,86",Deleterious,2,Damaging,"31,13","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_080,9,5073770,G,T,missense_variant(MODERATE|MISSENSE|Gtc/Ttc|p.Val617Phe/c.1849G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),13165,141,13333,"0,0105752644",0,0,0,0,1,0,0,0,1,"0,0233",NO,COSM12600,central_nervous_system. haematopoietic_and_lymphoid_tissue. lung,1. 37620. 3,NO,rs77375493,YES,"0,0006919",NO,NO,"-3,86",Deleterious,2,Damaging,"31,06","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_081,9,5073770,G,T,missense_variant(MODERATE|MISSENSE|Gtc/Ttc|p.Val617Phe/c.1849G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),4319,53,4413,"0,0120099705",0,0,0,0,1,0,0,0,1,"0,0233",NO,COSM12600,central_nervous_system. haematopoietic_and_lymphoid_tissue. lung,1. 37620. 3,NO,rs77375493,YES,"0,0006919",NO,NO,"-3,86",Deleterious,2,Damaging,"30,92",14
"low bq, low freq, many artifacts",UPN2_084,9,5073770,G,T,missense_variant(MODERATE|MISSENSE|Gtc/Ttc|p.Val617Phe/c.1849G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),25219,256,25517,"0,0100325273",0,0,0,0,1,0,0,0,1,"0,0233",NO,COSM12600,central_nervous_system. haematopoietic_and_lymphoid_tissue. lung,1. 37620. 3,NO,rs77375493,YES,"0,0006919",NO,NO,"-3,86",Deleterious,2,Damaging,"31,3","14,46"
"low freq, many artifacts",UPN2_064,9,5073771,T,A,missense_variant(MODERATE|MISSENSE|gTc/gAc|p.Val617Asp/c.1850T>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),2639,34,2684,"0,0126676602",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"31,36","30,47"
"low bq, low freq, many artifacts, many samples",UPN2_059,9,5073776,G,T,stop_gained(HIGH|NONSENSE|Gga/Tga|p.Gly619*/c.1855G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),2062,22,2091,"0,0105212817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,3",14
"low bq, low freq, many artifacts, many samples",UPN2_074,9,5073776,G,T,stop_gained(HIGH|NONSENSE|Gga/Tga|p.Gly619*/c.1855G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),13753,141,13955,"0,0101039054",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,43","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_081,9,5073776,G,T,stop_gained(HIGH|NONSENSE|Gga/Tga|p.Gly619*/c.1855G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),4345,45,4413,"0,0101971448",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,38","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_059,9,5073781,C,A,missense_variant(MODERATE|MISSENSE|gaC/gaA|p.Asp620Glu/c.1860C>A|1132|JAK2|protein_coding|CODING|ENST00000381652|14|A),2058,23,2089,"0,0110100527",0,0,0,0,1,0,0,0,1,NO,NO,COSM27063,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,1,Tolerated,"29,46","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_059,9,5073782,G,T,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu621*/c.1861G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),2064,23,2089,"0,0110100527",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,35",14
"low bq, low freq, many artifacts, many samples",UPN2_061,9,5073782,G,T,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu621*/c.1861G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),16812,177,17036,"0,0103897629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,6","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_065,9,5073782,G,T,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu621*/c.1861G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),7535,88,7649,"0,0115047719",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,31","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_066,9,5073782,G,T,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu621*/c.1861G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),31802,334,32244,"0,0103585163",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,38","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_073,9,5073782,G,T,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu621*/c.1861G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),6006,62,6075,"0,0102057613",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,56","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_074,9,5073782,G,T,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu621*/c.1861G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),13758,151,13949,"0,0108251488",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,4","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_075,9,5073782,G,T,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu621*/c.1861G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),17111,174,17320,"0,0100461894",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,32","15,74"
"low bq, low freq, many artifacts",UPN2_080,9,5073782,G,T,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu621*/c.1861G>T|1132|JAK2|protein_coding|CODING|ENST00000381652|14|T),13127,138,13321,"0,0103595826",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,33","14,19"
"low freq, many artifacts",UPN2_056,11,119148875,G,A,splice_acceptor_variant+intron_variant(HIGH|||c.1096-1G>A|906|CBL|protein_coding|CODING|ENST00000264033|7|A),1430,23,1456,"0,0157967033",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,,,,,"30,19","33,78"
"low bq, low freq, many artifacts, many samples",UPN2_044,11,119148876,G,T,stop_gained+splice_region_variant(HIGH|NONSENSE|Gaa/Taa|p.Glu366*/c.1096G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),5107,54,5174,"0,0104367994",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,99","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_067,11,119148876,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu366*/c.1096G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),55188,564,55845,"0,0100993822",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,41","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_072,11,119148876,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu366*/c.1096G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),17516,185,17719,"0,0104407698",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,47","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_075,11,119148876,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu366*/c.1096G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),17548,186,17755,"0,0104759223",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,45","16,08"
"low bq, low freq, many artifacts, many samples",UPN2_081,11,119148876,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu366*/c.1096G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),12435,151,12610,"0,0119746233",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,51","14,59"
"low bq, low freq, many artifacts",UPN2_088,11,119148876,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu366*/c.1096G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),31311,327,31709,"0,0103125296",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,5","14,54"
"low freq, many artifacts",UPN2_056,11,119148894,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys372Arg/c.1114T>C|906|CBL|protein_coding|CODING|ENST00000264033|8|C),1440,22,1465,"0,0150170648",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-10,96",Deleterious,"0,002",Damaging,"33,98","31,82"
"low bq, low freq, many artifacts, many samples",UPN2_047,11,119148902,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met374Ile/c.1122G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),13092,175,13329,"0,013129267",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,74,Tolerated,"31,34","20,94"
"low bq, low freq, many artifacts, many samples",UPN2_059,11,119148902,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met374Ile/c.1122G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),12193,148,12383,"0,0119518695",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,74,Tolerated,"30,04","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_060,11,119148902,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met374Ile/c.1122G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),23378,291,23777,"0,0122387181",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,74,Tolerated,"30,14","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_061,11,119148902,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met374Ile/c.1122G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),26172,305,26622,"0,01145669",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,74,Tolerated,"30,12","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_062,11,119148902,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met374Ile/c.1122G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),20985,235,21328,"0,0110183796",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,74,Tolerated,"30,19","15,92"
"low bq, low freq, many artifacts, many samples",UPN2_063,11,119148902,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met374Ile/c.1122G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),25820,272,26212,"0,0103769266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,74,Tolerated,"30,08","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_064,11,119148902,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met374Ile/c.1122G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),14497,164,14724,"0,0111382776",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,74,Tolerated,"30,09","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_065,11,119148902,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met374Ile/c.1122G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),27956,360,28438,"0,0126591181",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,74,Tolerated,"30,05","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_066,11,119148902,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met374Ile/c.1122G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),56565,694,57522,"0,0120649491",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,74,Tolerated,"30,12","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_067,11,119148902,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met374Ile/c.1122G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),54993,693,55929,"0,0123907096",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,74,Tolerated,"30,09","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_068,11,119148902,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met374Ile/c.1122G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),33672,356,34179,"0,0104157524",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,74,Tolerated,"30,15","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_069,11,119148902,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met374Ile/c.1122G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),30213,335,30694,"0,0109141852",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,74,Tolerated,"30,07","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_071,11,119148902,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met374Ile/c.1122G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),12509,151,12712,"0,01187854",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,74,Tolerated,"30,09","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_072,11,119148902,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met374Ile/c.1122G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),17501,200,17759,"0,0112618954",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,74,Tolerated,"30,04","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_073,11,119148902,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met374Ile/c.1122G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),12695,157,12898,"0,0121724298",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,74,Tolerated,30,"15,05"
"low bq, low freq, many artifacts, many samples",UPN2_074,11,119148902,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met374Ile/c.1122G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),20274,230,20558,"0,0111878587",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,74,Tolerated,"30,09","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_075,11,119148902,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met374Ile/c.1122G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),17517,209,17792,"0,0117468525",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,74,Tolerated,"30,04","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_076,11,119148902,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met374Ile/c.1122G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),26252,280,26642,"0,0105097215",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,74,Tolerated,"30,2","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_077,11,119148902,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met374Ile/c.1122G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),30981,374,31508,"0,0118700013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,74,Tolerated,"30,1","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_078,11,119148902,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met374Ile/c.1122G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),22945,269,23326,"0,0115321958",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,74,Tolerated,"30,15","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_080,11,119148902,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met374Ile/c.1122G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),17947,208,18249,"0,0113978848",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,74,Tolerated,"30,05","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_081,11,119148902,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met374Ile/c.1122G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),12439,147,12636,"0,0116334283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,74,Tolerated,"30,12","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_082,11,119148902,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met374Ile/c.1122G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),40840,467,41527,"0,0112456956",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,74,Tolerated,"30,06","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_083,11,119148902,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met374Ile/c.1122G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),30276,344,30782,"0,0111753622",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,74,Tolerated,"30,2","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_084,11,119148902,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met374Ile/c.1122G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),42408,491,43083,"0,0113966066",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,74,Tolerated,"30,09","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_085,11,119148902,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met374Ile/c.1122G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),56735,674,57651,"0,0116910374",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,74,Tolerated,"30,08","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_086,11,119148902,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met374Ile/c.1122G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),53749,567,54587,"0,0103870885",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,74,Tolerated,"30,13","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_087,11,119148902,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met374Ile/c.1122G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),38852,449,39474,"0,0113745757",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,74,Tolerated,"30,02","14,33"
"low bq, low freq, many artifacts",UPN2_088,11,119148902,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met374Ile/c.1122G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),31285,349,31761,"0,010988319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,74,Tolerated,"30,02","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_059,11,119148903,G,T,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly375Cys/c.1123G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),12188,175,12381,"0,014134561",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,45",Deleterious,0,Damaging,"29,48","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_060,11,119148903,G,T,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly375Cys/c.1123G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),23417,312,23768,"0,0131268933",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,45",Deleterious,0,Damaging,"29,58","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_061,11,119148903,G,T,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly375Cys/c.1123G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),26195,372,26620,"0,0139744553",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,45",Deleterious,0,Damaging,"29,57","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_062,11,119148903,G,T,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly375Cys/c.1123G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),20989,277,21321,"0,0129918859",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,45",Deleterious,0,Damaging,"29,71","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_063,11,119148903,G,T,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly375Cys/c.1123G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),25765,373,26205,"0,0142339248",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,45",Deleterious,0,Damaging,"29,52","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_064,11,119148903,G,T,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly375Cys/c.1123G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),14498,196,14725,"0,0133106961",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,45",Deleterious,0,Damaging,"29,49","15,25"
"low bq, low freq, many artifacts, many samples",UPN2_065,11,119148903,G,T,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly375Cys/c.1123G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),27941,433,28436,"0,0152271768",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,45",Deleterious,0,Damaging,"29,5","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_066,11,119148903,G,T,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly375Cys/c.1123G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),56538,842,57505,"0,014642205",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,45",Deleterious,0,Damaging,"29,52",15
"low bq, low freq, many artifacts, many samples",UPN2_067,11,119148903,G,T,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly375Cys/c.1123G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),54976,813,55919,"0,0145388866",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,45",Deleterious,0,Damaging,"29,45","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_068,11,119148903,G,T,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly375Cys/c.1123G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),33667,412,34173,"0,0120563018",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,45",Deleterious,0,Damaging,"29,64","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_069,11,119148903,G,T,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly375Cys/c.1123G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),30244,388,30691,"0,0126421426",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,45",Deleterious,0,Damaging,"29,51","15,64"
"low bq, low freq, many artifacts, many samples",UPN2_070,11,119148903,G,T,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly375Cys/c.1123G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),21131,296,21479,"0,0137809023",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,45",Deleterious,0,Damaging,"29,59","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_071,11,119148903,G,T,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly375Cys/c.1123G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),12508,173,12708,"0,0136134718",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,45",Deleterious,0,Damaging,"29,51","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_072,11,119148903,G,T,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly375Cys/c.1123G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),17511,224,17755,"0,0126161645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,45",Deleterious,0,Damaging,"29,41","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_073,11,119148903,G,T,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly375Cys/c.1123G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),12692,184,12895,"0,0142690965",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,45",Deleterious,0,Damaging,"29,41","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_074,11,119148903,G,T,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly375Cys/c.1123G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),20217,300,20554,"0,0145956991",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,45",Deleterious,0,Damaging,"29,58","15,31"
"low bq, low freq, many artifacts, many samples",UPN2_075,11,119148903,G,T,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly375Cys/c.1123G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),17489,263,17789,"0,0147844173",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,45",Deleterious,0,Damaging,"29,54","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_076,11,119148903,G,T,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly375Cys/c.1123G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),26227,347,26637,"0,0130269925",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,45",Deleterious,0,Damaging,"29,62","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_077,11,119148903,G,T,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly375Cys/c.1123G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),31055,384,31496,"0,0121920244",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,45",Deleterious,0,Damaging,"29,53","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_078,11,119148903,G,T,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly375Cys/c.1123G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),22988,284,23322,"0,0121773433",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,45",Deleterious,0,Damaging,"29,62","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_079,11,119148903,G,T,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly375Cys/c.1123G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),12931,179,13143,"0,0136194172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,45",Deleterious,0,Damaging,"29,5","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_080,11,119148903,G,T,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly375Cys/c.1123G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),17962,248,18244,"0,0135935102",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,45",Deleterious,0,Damaging,"29,43","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_081,11,119148903,G,T,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly375Cys/c.1123G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),12412,194,12631,"0,0153590373",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,45",Deleterious,0,Damaging,"29,54","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_082,11,119148903,G,T,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly375Cys/c.1123G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),40780,618,41518,"0,0148851101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,45",Deleterious,0,Damaging,"29,49","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_083,11,119148903,G,T,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly375Cys/c.1123G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),30308,406,30776,"0,0131920977",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,45",Deleterious,0,Damaging,"29,72","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_084,11,119148903,G,T,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly375Cys/c.1123G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),42403,580,43074,"0,0134651994",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,45",Deleterious,0,Damaging,"29,63","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_085,11,119148903,G,T,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly375Cys/c.1123G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),56686,814,57640,"0,0141221374",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,45",Deleterious,0,Damaging,"29,53","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_086,11,119148903,G,T,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly375Cys/c.1123G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),53731,734,54581,"0,0134479031",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,45",Deleterious,0,Damaging,"29,54","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_087,11,119148903,G,T,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly375Cys/c.1123G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),38865,527,39472,"0,0133512363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,45",Deleterious,0,Damaging,"29,47","14,76"
"low bq, low freq, many artifacts",UPN2_088,11,119148903,G,T,missense_variant(MODERATE|MISSENSE|Ggc/Tgc|p.Gly375Cys/c.1123G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),31195,499,31755,"0,0157140608",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,45",Deleterious,0,Damaging,"29,48","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_059,11,119148904,G,T,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly375Val/c.1124G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),12222,138,12377,"0,0111497132",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,48",Deleterious,0,Damaging,"29,74","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_060,11,119148904,G,T,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly375Val/c.1124G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),23401,312,23762,"0,0131302079",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,48",Deleterious,0,Damaging,"29,83","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_061,11,119148904,G,T,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly375Val/c.1124G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),26287,276,26618,"0,0103689233",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,48",Deleterious,0,Damaging,"29,76","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_062,11,119148904,G,T,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly375Val/c.1124G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),21062,220,21316,"0,0103208857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,48",Deleterious,0,Damaging,"29,84","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_063,11,119148904,G,T,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly375Val/c.1124G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),25848,300,26200,"0,0114503817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,48",Deleterious,0,Damaging,"29,85","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_064,11,119148904,G,T,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly375Val/c.1124G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),14539,153,14722,"0,0103926097",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,48",Deleterious,0,Damaging,"29,82","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_065,11,119148904,G,T,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly375Val/c.1124G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),28007,348,28430,"0,0122405909",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,48",Deleterious,0,Damaging,"29,71","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_066,11,119148904,G,T,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly375Val/c.1124G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),56728,662,57498,"0,0115134439",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,48",Deleterious,0,Damaging,"29,81","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_067,11,119148904,G,T,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly375Val/c.1124G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),55103,706,55913,"0,0126267594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,48",Deleterious,0,Damaging,"29,75","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_068,11,119148904,G,T,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly375Val/c.1124G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),33719,380,34169,"0,0111211917",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,48",Deleterious,0,Damaging,"29,98","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_069,11,119148904,G,T,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly375Val/c.1124G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),30275,348,30687,"0,011340307",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,48",Deleterious,0,Damaging,"29,86","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_070,11,119148904,G,T,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly375Val/c.1124G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),21177,232,21478,"0,0108017506",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,48",Deleterious,0,Damaging,"29,8","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_071,11,119148904,G,T,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly375Val/c.1124G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),12558,136,12705,"0,0107044471",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,48",Deleterious,0,Damaging,"29,82","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_072,11,119148904,G,T,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly375Val/c.1124G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),17509,194,17753,"0,0109277305",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,48",Deleterious,0,Damaging,"29,87","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_073,11,119148904,G,T,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly375Val/c.1124G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),12701,164,12894,"0,0127190942",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,48",Deleterious,0,Damaging,"29,65","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_074,11,119148904,G,T,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly375Val/c.1124G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),20292,234,20555,"0,0113840915",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,48",Deleterious,0,Damaging,"29,85","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_075,11,119148904,G,T,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly375Val/c.1124G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),17527,215,17784,"0,0120895187",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,48",Deleterious,0,Damaging,"29,71","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_077,11,119148904,G,T,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly375Val/c.1124G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),31051,352,31490,"0,0111781518",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,48",Deleterious,0,Damaging,"29,79","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_079,11,119148904,G,T,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly375Val/c.1124G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),12977,148,13140,"0,0112633181",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,48",Deleterious,0,Damaging,"29,73","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_080,11,119148904,G,T,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly375Val/c.1124G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),17978,224,18240,"0,0122807018",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,48",Deleterious,0,Damaging,"29,79","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_081,11,119148904,G,T,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly375Val/c.1124G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),12433,165,12628,"0,0130662021",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,48",Deleterious,0,Damaging,"29,8","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_082,11,119148904,G,T,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly375Val/c.1124G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),40918,500,41507,"0,0120461609",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,48",Deleterious,0,Damaging,"29,75","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_083,11,119148904,G,T,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly375Val/c.1124G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),30390,332,30766,"0,0107911331",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,48",Deleterious,0,Damaging,"29,98","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_084,11,119148904,G,T,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly375Val/c.1124G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),42498,498,43075,"0,0115612304",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,48",Deleterious,0,Damaging,"29,94","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_085,11,119148904,G,T,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly375Val/c.1124G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),56813,720,57630,"0,012493493",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,48",Deleterious,0,Damaging,"29,78","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_086,11,119148904,G,T,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly375Val/c.1124G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),53876,583,54566,"0,0106843089",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,48",Deleterious,0,Damaging,"29,83","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_087,11,119148904,G,T,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly375Val/c.1124G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),38912,473,39465,"0,0119853034",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,48",Deleterious,0,Damaging,"29,79","15,16"
"low bq, low freq, many artifacts",UPN2_088,11,119148904,G,T,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly375Val/c.1124G>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),31324,351,31753,"0,0110540736",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,48",Deleterious,0,Damaging,"29,71","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_059,11,119148907,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser376Tyr/c.1127C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),12187,139,12374,"0,011233231",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"30,75","15,41"
"low bq, low freq, many artifacts, many samples",UPN2_065,11,119148907,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser376Tyr/c.1127C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),28024,297,28430,"0,0104467112",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"30,69","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_067,11,119148907,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser376Tyr/c.1127C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),55095,600,55904,"0,0107326846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"30,66","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_069,11,119148907,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser376Tyr/c.1127C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),30195,322,30682,"0,0104947526",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"30,69","15,96"
"low bq, low freq, many artifacts, many samples",UPN2_070,11,119148907,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser376Tyr/c.1127C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),21157,234,21476,"0,0108958838",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"30,76","15,61"
"low bq, low freq, many artifacts, many samples",UPN2_072,11,119148907,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser376Tyr/c.1127C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),17456,180,17754,"0,0101385603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"30,69","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_073,11,119148907,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser376Tyr/c.1127C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),12709,136,12891,"0,0105499961",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"30,62","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_074,11,119148907,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser376Tyr/c.1127C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),20286,208,20553,"0,0101201771",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"30,77","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_075,11,119148907,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser376Tyr/c.1127C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),17497,194,17784,"0,010908682",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"30,59","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_077,11,119148907,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser376Tyr/c.1127C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),31032,328,31491,"0,0104156743",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"30,68","15,69"
"low bq, low freq, many artifacts, many samples",UPN2_078,11,119148907,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser376Tyr/c.1127C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),22977,241,23311,"0,0103384668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"30,73","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_079,11,119148907,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser376Tyr/c.1127C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),12941,134,13139,"0,0101986453",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"30,7","15,81"
"low bq, low freq, many artifacts, many samples",UPN2_080,11,119148907,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser376Tyr/c.1127C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),17982,199,18235,"0,0109130792",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"30,67","15,64"
"low bq, low freq, many artifacts, many samples",UPN2_081,11,119148907,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser376Tyr/c.1127C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),12420,165,12624,"0,0130703422",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"30,79","15,92"
"low bq, low freq, many artifacts, many samples",UPN2_082,11,119148907,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser376Tyr/c.1127C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),40883,438,41499,"0,0105544712",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"30,7","15,42"
"low bq, low freq, many artifacts, many samples",UPN2_085,11,119148907,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser376Tyr/c.1127C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),56792,602,57623,"0,0104472173",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"30,69","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_086,11,119148907,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser376Tyr/c.1127C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),53791,563,54561,"0,0103187258",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"30,74","15,51"
"low bq, low freq, many artifacts, many samples",UPN2_087,11,119148907,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser376Tyr/c.1127C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),38887,417,39457,"0,0105684669",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"30,66","15,16"
"low bq, low freq, many artifacts",UPN2_088,11,119148907,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser376Tyr/c.1127C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),31261,351,31744,"0,0110572077",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"30,69","15,68"
"low bq, low freq, many artifacts, many samples",UPN2_059,11,119148914,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe378Leu/c.1134C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),12215,136,12376,"0,010989011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,66",Deleterious,1,Damaging,"31,53","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_060,11,119148914,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe378Leu/c.1134C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),23463,255,23766,"0,0107296137",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,66",Deleterious,1,Damaging,"31,61","17,02"
"low bq, low freq, many artifacts, many samples",UPN2_061,11,119148914,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe378Leu/c.1134C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),26243,286,26614,"0,0107462238",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,66",Deleterious,1,Damaging,"31,54","15,81"
"low bq, low freq, many artifacts, many samples",UPN2_064,11,119148914,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe378Leu/c.1134C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),14509,169,14722,"0,0114794186",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,66",Deleterious,1,Damaging,"31,47","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_065,11,119148914,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe378Leu/c.1134C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),28026,333,28433,"0,0117117434",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,66",Deleterious,1,Damaging,"31,56","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_066,11,119148914,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe378Leu/c.1134C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),56620,675,57496,"0,0117399471",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,66",Deleterious,1,Damaging,"31,59","15,92"
"low bq, low freq, many artifacts, many samples",UPN2_067,11,119148914,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe378Leu/c.1134C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),55128,619,55906,"0,0110721568",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,66",Deleterious,1,Damaging,"31,5","16,01"
"low bq, low freq, many artifacts, many samples",UPN2_068,11,119148914,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe378Leu/c.1134C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),33720,356,34168,"0,0104191056",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,66",Deleterious,1,Damaging,"31,61","15,75"
"low bq, low freq, many artifacts, many samples",UPN2_069,11,119148914,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe378Leu/c.1134C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),30266,335,30682,"0,0109184538",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,66",Deleterious,1,Damaging,"31,53","16,59"
"low bq, low freq, many artifacts, many samples",UPN2_070,11,119148914,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe378Leu/c.1134C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),21192,246,21481,"0,0114519808",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,66",Deleterious,1,Damaging,"31,55","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_071,11,119148914,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe378Leu/c.1134C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),12547,137,12703,"0,010784854",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,66",Deleterious,1,Damaging,"31,41","15,55"
"low bq, low freq, many artifacts, many samples",UPN2_072,11,119148914,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe378Leu/c.1134C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),17519,185,17752,"0,010421361",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,66",Deleterious,1,Damaging,"31,54","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_073,11,119148914,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe378Leu/c.1134C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),12720,139,12891,"0,0107827166",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,66",Deleterious,1,Damaging,"31,51","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_074,11,119148914,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe378Leu/c.1134C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),20279,228,20554,"0,0110927313",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,66",Deleterious,1,Damaging,"31,58","16,11"
"low bq, low freq, many artifacts, many samples",UPN2_075,11,119148914,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe378Leu/c.1134C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),17548,199,17784,"0,0111898336",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,66",Deleterious,1,Damaging,"31,54","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_077,11,119148914,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe378Leu/c.1134C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),31071,331,31496,"0,010509271",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,66",Deleterious,1,Damaging,"31,57","15,53"
"low bq, low freq, many artifacts, many samples",UPN2_078,11,119148914,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe378Leu/c.1134C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),23005,265,23314,"0,0113665609",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,66",Deleterious,1,Damaging,"31,61","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_081,11,119148914,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe378Leu/c.1134C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),12442,148,12623,"0,0117246296",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,66",Deleterious,1,Damaging,"31,62","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_082,11,119148914,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe378Leu/c.1134C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),40899,478,41503,"0,0115172397",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,66",Deleterious,1,Damaging,"31,52","15,55"
"low bq, low freq, many artifacts, many samples",UPN2_084,11,119148914,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe378Leu/c.1134C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),42495,463,43071,"0,0107496924",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,66",Deleterious,1,Damaging,"31,54","15,76"
"low bq, low freq, many artifacts, many samples",UPN2_085,11,119148914,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe378Leu/c.1134C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),56864,614,57633,"0,0106536186",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,66",Deleterious,1,Damaging,"31,5","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_086,11,119148914,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe378Leu/c.1134C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),53865,568,54562,"0,0104101756",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,66",Deleterious,1,Damaging,"31,59","15,49"
"low bq, low freq, many artifacts, many samples",UPN2_087,11,119148914,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe378Leu/c.1134C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),38941,441,39459,"0,0111761575",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,66",Deleterious,1,Damaging,"31,49","15,64"
"low bq, low freq, many artifacts",UPN2_088,11,119148914,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe378Leu/c.1134C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),31284,385,31745,"0,0121278942",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,66",Deleterious,1,Damaging,"31,55","15,46"
"low bq, low freq, many artifacts, many samples",UPN2_003,11,119148915,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln379Lys/c.1135C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),2507,29,2542,"0,0114083399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"30,43",14
"low bq, low freq, many artifacts, many samples",UPN2_042,11,119148915,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln379Lys/c.1135C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),12119,131,12282,"0,0106660153",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,16","15,58"
"low bq, low freq, many artifacts, many samples",UPN2_005,11,119148915,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln379Lys/c.1135C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),4391,49,4447,"0,0110186643",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"30,59","15,53"
"low bq, low freq, many artifacts, many samples",UPN2_045,11,119148915,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln379Lys/c.1135C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),12446,137,12613,"0,0108618092",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,27","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_047,11,119148915,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln379Lys/c.1135C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),13157,137,13329,"0,0102783405",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,35","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_051,11,119148915,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln379Lys/c.1135C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),19669,208,19952,"0,01042502",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,33","15,61"
"low bq, low freq, many artifacts, many samples",UPN2_052,11,119148915,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln379Lys/c.1135C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),15892,164,16105,"0,0101831729",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,19","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_053,11,119148915,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln379Lys/c.1135C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),23260,240,23547,"0,0101923812",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,32","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_057,11,119148915,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln379Lys/c.1135C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),24762,253,25076,"0,0100893284",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,19","15,65"
"low bq, low freq, many artifacts, many samples",UPN2_058,11,119148915,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln379Lys/c.1135C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),34278,357,34716,"0,0102834428",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,11","15,51"
"low bq, low freq, many artifacts, many samples",UPN2_059,11,119148915,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln379Lys/c.1135C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),12130,207,12376,"0,0167259211",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,3",15
"low bq, low freq, many artifacts, many samples",UPN2_060,11,119148915,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln379Lys/c.1135C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),23279,424,23766,"0,0178406126",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,37","15,58"
"low bq, low freq, many artifacts, many samples",UPN2_013,11,119148915,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln379Lys/c.1135C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),9364,98,9485,"0,0103321033",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"30,57","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_061,11,119148915,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln379Lys/c.1135C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),26054,472,26614,"0,0177350267",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,39","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_062,11,119148915,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln379Lys/c.1135C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),20895,374,21314,"0,0175471521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,47","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_063,11,119148915,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln379Lys/c.1135C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),25666,456,26203,"0,0174025875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,4","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_064,11,119148915,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln379Lys/c.1135C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),14401,276,14722,"0,0187474528",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,38","15,74"
"low bq, low freq, many artifacts, many samples",UPN2_065,11,119148915,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln379Lys/c.1135C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),27880,489,28434,"0,017197721",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,39","15,49"
"low bq, low freq, many artifacts, many samples",UPN2_066,11,119148915,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln379Lys/c.1135C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),56395,953,57495,"0,0165753544",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,43","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_067,11,119148915,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln379Lys/c.1135C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),54764,1027,55914,"0,0183674929",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,34","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_068,11,119148915,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln379Lys/c.1135C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),33517,565,34170,"0,0165349722",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,47","15,81"
"low bq, low freq, many artifacts, many samples",UPN2_069,11,119148915,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln379Lys/c.1135C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),30044,551,30683,"0,0179578268",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,33","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_070,11,119148915,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln379Lys/c.1135C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),21051,376,21480,"0,0175046555",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,42","15,81"
"low bq, low freq, many artifacts, many samples",UPN2_071,11,119148915,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln379Lys/c.1135C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),12451,227,12704,"0,0178683879",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,36","15,62"
"low bq, low freq, many artifacts, many samples",UPN2_072,11,119148915,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln379Lys/c.1135C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),17426,285,17752,"0,0160545291",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,34","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_073,11,119148915,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln379Lys/c.1135C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),12610,242,12891,"0,0187727872",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,34","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_074,11,119148915,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln379Lys/c.1135C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),20120,370,20554,"0,0180013623",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,36","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_075,11,119148915,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln379Lys/c.1135C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),17373,344,17783,"0,0193443176",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,38","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_076,11,119148915,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln379Lys/c.1135C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),26123,435,26626,"0,0163374146",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,49","15,94"
"low bq, low freq, many artifacts, many samples",UPN2_077,11,119148915,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln379Lys/c.1135C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),30850,580,31498,"0,0184138675",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,41","15,83"
"low bq, low freq, many artifacts, many samples",UPN2_078,11,119148915,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln379Lys/c.1135C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),22873,371,23315,"0,0159125027",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,46","15,74"
"low bq, low freq, many artifacts, many samples",UPN2_079,11,119148915,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln379Lys/c.1135C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),12860,248,13137,"0,0188779782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,32","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_080,11,119148915,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln379Lys/c.1135C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),17854,340,18234,"0,0186464846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,45","15,99"
"low bq, low freq, many artifacts, many samples",UPN2_081,11,119148915,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln379Lys/c.1135C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),12350,238,12622,"0,0188559658",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,37","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_082,11,119148915,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln379Lys/c.1135C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),40561,804,41506,"0,0193706934",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,39","15,65"
"low bq, low freq, many artifacts, many samples",UPN2_083,11,119148915,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln379Lys/c.1135C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),30200,501,30774,"0,0162799766",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,46","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_084,11,119148915,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln379Lys/c.1135C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),42152,733,43072,"0,0170180163",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,4","15,53"
"low bq, low freq, many artifacts, many samples",UPN2_085,11,119148915,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln379Lys/c.1135C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),56446,1033,57637,"0,0179225151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,39","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_086,11,119148915,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln379Lys/c.1135C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),53472,940,54560,"0,017228739",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,44","15,56"
"low bq, low freq, many artifacts, many samples",UPN2_087,11,119148915,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln379Lys/c.1135C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),38672,695,39458,"0,0176136652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,32","15,21"
"low bq, low freq, many artifacts",UPN2_088,11,119148915,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln379Lys/c.1135C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),31102,552,31747,"0,0173874697",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,34","15,34"
"inspected, many artifacts",UPN2_056,11,119148917,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln379His/c.1137A>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),1426,36,1465,"0,0245733788",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,61",Deleterious,"0,001",Damaging,"33,98","31,25"
"low freq, many artifacts",UPN2_044,11,119148927,A,G,missense_variant(MODERATE|MISSENSE|Ata/Gta|p.Ile383Val/c.1147A>G|906|CBL|protein_coding|CODING|ENST00000264033|8|G),5113,56,5191,"0,0107879021",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,96",Neutral,"0,031",Damaging,"33,13","33,88"
"low freq, many artifacts",UPN2_056,11,119148929,A,G,missense_variant(MODERATE|MISSENSE|atA/atG|p.Ile383Met/c.1149A>G|906|CBL|protein_coding|CODING|ENST00000264033|8|G),1436,24,1465,"0,0163822526",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,84",Deleterious,0,Damaging,"32,44","32,88"
"low bq, low freq, many artifacts, many samples",UPN2_042,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),12079,162,12268,"0,0132050864",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,88","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_043,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),13918,183,14133,"0,0129484186",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,96","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_044,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),5101,71,5182,"0,0137012736",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"29,07","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_045,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),12402,159,12597,"0,0126220529",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,93","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_046,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),23256,291,23605,"0,0123278966",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,98","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_047,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),13069,189,13317,"0,0141923857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,92","15,25"
"low bq, low freq, many artifacts, many samples",UPN2_049,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),11326,132,11486,"0,0114922514",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,93","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_050,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),17943,252,18280,"0,013785558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,94","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_051,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),19634,213,19922,"0,0106916976",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,94","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_052,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),15793,209,16081,"0,0129967042",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,95","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_053,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),23119,316,23514,"0,0134388024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,95","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_054,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),15454,217,15733,"0,0137926651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,97","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_055,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),21630,276,21985,"0,0125540141",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,88","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_090,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),8457,100,8580,"0,0116550117",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,49","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_057,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),24651,333,25042,"0,0132976599",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,92","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_058,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),34123,450,34671,"0,0129791468",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,81",15
"low bq, many samples",UPN2_059,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),11989,318,12329,"0,0257928461",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,7","15,13"
"low bq, many samples",UPN2_060,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),23083,554,23697,"0,0233784867",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,73","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_091,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),8832,108,8953,"0,0120629956",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,45","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_092,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),8214,97,8317,"0,0116628592",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,55","14,87"
"low bq, many samples",UPN2_061,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),25856,627,26527,"0,0236362951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,77","15,3"
"low bq, low freq, many artifacts, many samples",UPN2_062,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),20815,409,21247,"0,0192497764",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,73","15,57"
"low bq, many samples",UPN2_063,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),25430,652,26120,"0,0249617152",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,74","14,9"
"low bq, many samples",UPN2_064,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),14289,367,14676,"0,0250068138",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,75","15,05"
"low bq, many samples",UPN2_065,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),27642,639,28343,"0,0225452493",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,68","15,12"
"low bq, many samples",UPN2_066,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),55946,1261,57279,"0,0220150491",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,76","15,31"
"low bq, many samples",UPN2_067,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),54312,1336,55727,"0,0239740162",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,66","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_068,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),33296,728,34084,"0,0213589954",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,8","15,43"
"low bq, many samples",UPN2_069,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),29801,731,30588,"0,0238982608",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,75","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_070,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),20900,450,21400,"0,0210280374",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,79","15,22"
"low bq, many samples",UPN2_071,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),12360,288,12664,"0,0227416298",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,73","15,1"
"low bq, many samples",UPN2_072,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),17202,456,17700,"0,0257627119",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,68","15,19"
"low bq, many samples",UPN2_073,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),12510,314,12845,"0,0244453095",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,7","15,11"
"low bq, many samples",UPN2_074,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),19964,483,20492,"0,0235701737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,75","15,23"
"low bq, many samples",UPN2_075,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),17227,439,17721,"0,0247728683",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,72","15,62"
"low bq, low freq, many artifacts, many samples",UPN2_076,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),25911,582,26537,"0,0219316426",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,85","14,89"
"low bq, many samples",UPN2_077,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),30588,716,31388,"0,0228112655",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,71","15,06"
"low bq, many samples",UPN2_078,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),22633,572,23239,"0,0246137958",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,87","15,27"
"low bq, many samples",UPN2_079,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),12779,294,13095,"0,0224513173",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,69","15,21"
"low bq, many samples",UPN2_080,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),17687,436,18170,"0,0239955971",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,7","14,98"
"low bq, many samples",UPN2_081,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),12247,305,12570,"0,0242641209",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,67","15,37"
"low bq, many samples",UPN2_082,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),40231,1036,41339,"0,0250610803",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,68","15,3"
"low bq, low freq, many artifacts, many samples",UPN2_083,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),29991,648,30688,"0,0211157456",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,83","16,34"
"low bq, many samples",UPN2_084,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),41885,945,42906,"0,0220248916",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,76","15,51"
"low bq, many samples",UPN2_085,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),56034,1321,57464,"0,0229883057",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,74","15,14"
"low bq, many samples",UPN2_086,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),53006,1268,54379,"0,0233178249",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,76","15,05"
"low bq, many samples",UPN2_087,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),38326,922,39306,"0,0234569786",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,67","15,16"
"low bq, many samples",UPN2_088,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),30890,731,31657,"0,0230912594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,66","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_094,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),9458,114,9584,"0,0118948247",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,57","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_096,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),9377,119,9519,"0,0125013132",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,45","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_097,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),12075,162,12258,"0,013215859",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,44","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_098,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),10236,113,10365,"0,0109020743",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,34","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_100,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),9952,114,10081,"0,0113084019",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,51","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_101,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),12463,134,12628,"0,0106113399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,6","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_103,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),12224,133,12375,"0,0107474747",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,47","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_104,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),11905,130,12046,"0,0107919641",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,54","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_106,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),7608,97,7721,"0,0125631395",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,49","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_107,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),19739,217,20009,"0,0108451197",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,49","15,62"
"low bq, low freq, many artifacts, many samples",UPN2_108,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),14928,170,15119,"0,0112441299",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,47","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_109,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),15533,171,15737,"0,0108661117",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,42","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_110,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),12313,132,12466,"0,0105888015",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,35","15,36"
"low bq, low freq, many artifacts",UPN2_111,11,119148934,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala385Asp/c.1154C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),16353,201,16577,"0,0121252338",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,75,Tolerated,"28,53","14,91"
"low freq, many artifacts",UPN2_044,11,119148937,A,T,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu386Val/c.1157A>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),5090,71,5179,"0,0137092103",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,65",Deleterious,"0,017",Damaging,"33,58","32,49"
"low bq, low freq, many artifacts",UPN2_049,11,119148939,A,T,missense_variant(MODERATE|MISSENSE|Aat/Tat|p.Asn387Tyr/c.1159A>T|906|CBL|protein_coding|CODING|ENST00000264033|8|T),5943,63,6051,"0,0104115022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,31",Deleterious,1,Damaging,"33,41","20,78"
"many samples, low freq, no database",UPN2_014,11,119148955,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys392Arg/c.1175A>G|906|CBL|protein_coding|CODING|ENST00000264033|8|G),7819,99,7943,"0,0124638046",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,"0,311",Tolerated,"35,19","35,37"
"many samples, low freq, no database",UPN2_016,11,119148955,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys392Arg/c.1175A>G|906|CBL|protein_coding|CODING|ENST00000264033|8|G),6303,66,6385,"0,0103367267",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,"0,311",Tolerated,"35,23","34,05"
"many samples, low freq, no database",UPN2_017,11,119148955,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys392Arg/c.1175A>G|906|CBL|protein_coding|CODING|ENST00000264033|8|G),3328,36,3372,"0,0106761566",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,"0,311",Tolerated,"35,25","35,67"
"many samples, low freq, no database",UPN2_018,11,119148955,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys392Arg/c.1175A>G|906|CBL|protein_coding|CODING|ENST00000264033|8|G),6373,70,6468,"0,0108225108",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,"0,311",Tolerated,"35,22","35,04"
"many samples, low freq, no database",UPN2_020,11,119148955,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys392Arg/c.1175A>G|906|CBL|protein_coding|CODING|ENST00000264033|8|G),4632,53,4702,"0,0112717992",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,"0,311",Tolerated,"35,21","35,85"
"many samples, low freq, no database",UPN2_021,11,119148955,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys392Arg/c.1175A>G|906|CBL|protein_coding|CODING|ENST00000264033|8|G),6748,75,6844,"0,0109585038",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,"0,311",Tolerated,"35,21","35,12"
"many samples, low freq, no database",UPN2_027,11,119148955,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys392Arg/c.1175A>G|906|CBL|protein_coding|CODING|ENST00000264033|8|G),11001,120,11150,"0,0107623318",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,"0,311",Tolerated,"35,23","35,25"
"many samples, low freq, no database",UPN2_043,11,119148955,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys392Arg/c.1175A>G|906|CBL|protein_coding|CODING|ENST00000264033|8|G),6922,76,7039,"0,0107969882",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,"0,311",Tolerated,"34,71","34,72"
"many samples, low freq, no database",UPN2_044,11,119148955,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys392Arg/c.1175A>G|906|CBL|protein_coding|CODING|ENST00000264033|8|G),2545,30,2588,"0,0115919629",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,"0,311",Tolerated,"34,71","35,17"
"many samples, low freq, no database",UPN2_045,11,119148955,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys392Arg/c.1175A>G|906|CBL|protein_coding|CODING|ENST00000264033|8|G),6165,67,6267,"0,0106909207",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,"0,311",Tolerated,"34,56","34,21"
"many samples, low freq, no database",UPN2_046,11,119148955,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys392Arg/c.1175A>G|906|CBL|protein_coding|CODING|ENST00000264033|8|G),11561,132,11748,"0,0112359551",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,"0,311",Tolerated,"34,68","34,64"
"many samples, low freq, no database",UPN2_047,11,119148955,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys392Arg/c.1175A>G|906|CBL|protein_coding|CODING|ENST00000264033|8|G),6510,86,6632,"0,0129674306",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,"0,311",Tolerated,"34,76","34,21"
"many samples, low freq, no database",UPN2_036,11,119148955,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys392Arg/c.1175A>G|906|CBL|protein_coding|CODING|ENST00000264033|8|G),9480,101,9616,"0,0105033278",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,"0,311",Tolerated,"35,22","34,53"
"many samples, low freq, no database",UPN2_049,11,119148955,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys392Arg/c.1175A>G|906|CBL|protein_coding|CODING|ENST00000264033|8|G),5615,80,5725,"0,0139737991",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,"0,311",Tolerated,"34,65","34,39"
"many samples, low freq, no database",UPN2_050,11,119148955,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys392Arg/c.1175A>G|906|CBL|protein_coding|CODING|ENST00000264033|8|G),8945,106,9122,"0,0116202587",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,"0,311",Tolerated,"34,74","34,06"
"many samples, low freq, no database",UPN2_037,11,119148955,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys392Arg/c.1175A>G|906|CBL|protein_coding|CODING|ENST00000264033|8|G),13218,137,13409,"0,0102170184",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,"0,311",Tolerated,"35,24","35,24"
"many samples, low freq, no database",UPN2_051,11,119148955,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys392Arg/c.1175A>G|906|CBL|protein_coding|CODING|ENST00000264033|8|G),9772,108,9939,"0,0108662843",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,"0,311",Tolerated,"34,69","34,79"
"many samples, low freq, no database",UPN2_038,11,119148955,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys392Arg/c.1175A>G|906|CBL|protein_coding|CODING|ENST00000264033|8|G),16086,171,16302,"0,0104895105",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,"0,311",Tolerated,"35,25","35,35"
"many samples, low freq, no database",UPN2_039,11,119148955,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys392Arg/c.1175A>G|906|CBL|protein_coding|CODING|ENST00000264033|8|G),8565,102,8696,"0,0117295308",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,"0,311",Tolerated,"35,28","34,47"
"many samples, low freq, no database",UPN2_011,11,119148955,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys392Arg/c.1175A>G|906|CBL|protein_coding|CODING|ENST00000264033|8|G),16330,191,16587,"0,0115150419",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,"0,311",Tolerated,"35,07","35,54"
"many samples, low freq, no database",UPN2_090,11,119148955,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys392Arg/c.1175A>G|906|CBL|protein_coding|CODING|ENST00000264033|8|G),4231,46,4285,"0,0107351225",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,"0,311",Tolerated,"35,24","34,78"
"many samples, low freq, no database",UPN2_058,11,119148955,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys392Arg/c.1175A>G|906|CBL|protein_coding|CODING|ENST00000264033|8|G),16962,220,17281,"0,0127307447",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,"0,311",Tolerated,"34,7","34,77"
"many samples, low freq, no database",UPN2_059,11,119148955,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys392Arg/c.1175A>G|906|CBL|protein_coding|CODING|ENST00000264033|8|G),6089,63,6171,"0,0102090423",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,"0,311",Tolerated,"34,82","34,4"
"many samples, low freq, no database",UPN2_060,11,119148955,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys392Arg/c.1175A>G|906|CBL|protein_coding|CODING|ENST00000264033|8|G),11698,119,11849,"0,0100430416",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,"0,311",Tolerated,"34,82","34,98"
"many samples, low freq, no database",UPN2_040,11,119148955,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys392Arg/c.1175A>G|906|CBL|protein_coding|CODING|ENST00000264033|8|G),7588,102,7712,"0,0132261411",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,"0,311",Tolerated,"35,28","35,31"
"many samples, low freq, no database",UPN2_013,11,119148955,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys392Arg/c.1175A>G|906|CBL|protein_coding|CODING|ENST00000264033|8|G),4657,50,4725,"0,0105820106",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,"0,311",Tolerated,"35,07","35,4"
"many samples, low freq, no database",UPN2_062,11,119148955,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys392Arg/c.1175A>G|906|CBL|protein_coding|CODING|ENST00000264033|8|G),10479,115,10627,"0,0108214924",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,"0,311",Tolerated,"34,81","33,1"
"low freq, many artifacts",UPN2_063,11,119148955,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys392Arg/c.1175A>G|906|CBL|protein_coding|CODING|ENST00000264033|8|G),12886,132,13056,"0,0101102941",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,311,Tolerated,"34,88","35,06"
"many samples, low freq, no database",UPN2_072,11,119148955,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys392Arg/c.1175A>G|906|CBL|protein_coding|CODING|ENST00000264033|8|G),8729,102,8858,"0,0115150147",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,"0,311",Tolerated,"34,87","34,25"
"many samples, low freq, no database",UPN2_076,11,119148955,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys392Arg/c.1175A>G|906|CBL|protein_coding|CODING|ENST00000264033|8|G),13114,143,13296,"0,0107551143",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,"0,311",Tolerated,"34,89","34,6"
"many samples, low freq, no database",UPN2_084,11,119148955,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys392Arg/c.1175A>G|906|CBL|protein_coding|CODING|ENST00000264033|8|G),21147,236,21452,"0,0110013052",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,"0,311",Tolerated,"34,82","34,03"
"many samples, low freq, no database",UPN2_096,11,119148955,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys392Arg/c.1175A>G|906|CBL|protein_coding|CODING|ENST00000264033|8|G),4692,53,4749,"0,0111602443",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,"0,311",Tolerated,"35,24","35,55"
"many samples, low freq, no database",UPN2_097,11,119148955,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys392Arg/c.1175A>G|906|CBL|protein_coding|CODING|ENST00000264033|8|G),6044,64,6116,"0,0104643558",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,"0,311",Tolerated,"35,27","35,19"
"many samples, low freq, no database",UPN2_099,11,119148955,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys392Arg/c.1175A>G|906|CBL|protein_coding|CODING|ENST00000264033|8|G),3173,39,3219,"0,0121155638",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,"0,311",Tolerated,"35,21","33,26"
"many samples, low freq, no database",UPN2_108,11,119148955,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys392Arg/c.1175A>G|906|CBL|protein_coding|CODING|ENST00000264033|8|G),7454,77,7548,"0,0102013778",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,"0,311",Tolerated,"35,35","35,56"
"low freq, many artifacts",UPN2_006,11,119148963,C,A,missense_variant(MODERATE|MISSENSE|Ccc/Acc|p.Pro395Thr/c.1183C>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),4147,71,4227,"0,0167967826",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,57",Deleterious,0,Damaging,"35,26","34,69"
"inspected, many artifacts, strandbias",UPN2_044,11,119148969,G,A,missense_variant(MODERATE|MISSENSE|Gga/Aga|p.Gly397Arg/c.1189G>A|906|CBL|protein_coding|CODING|ENST00000264033|8|A),2514,63,2591,"0,0243149363",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,58",Deleterious,"0,051",Tolerated,"34,63","35,11"
"inspected, strandbias",UPN2_075,11,119149002,T,C,missense_variant(MODERATE|MISSENSE|Tgg/Cgg|p.Trp408Arg/c.1222T>C|906|CBL|protein_coding|CODING|ENST00000264033|8|C),15640,878,16571,"0,0529841289",0,0,0,0,1,1,0,0,2,NO,NO,COSM34060,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-13,29",Deleterious,0,Damaging,"35,32","34,55"
"low freq, many artifacts",UPN2_044,11,119149233,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln414Leu/c.1241A>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),3947,49,4016,"0,0122011952",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,"0,018",Damaging,"33,51","35,37"
"inspected, many artifacts",UPN2_068,11,119149247,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys419Ser/c.1255T>A|906|CBL|protein_coding|CODING|ENST00000264033|9|A),6051,137,6212,"0,0220540889",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,51",Deleterious,0,Damaging,"35,16","34,2"
"inspected, many artifacts",UPN2_048,11,119149249,C,G,missense_variant(MODERATE|MISSENSE|tgC/tgG|p.Cys419Trp/c.1257C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),1067,23,1101,"0,0208900999",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,94",Deleterious,0,Damaging,"34,2","35,04"
"low bq, low freq, many artifacts",UPN2_081,11,119149279,C,G,missense_variant(MODERATE|MISSENSE|atC/atG|p.Ile429Met/c.1287C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),6206,66,6311,"0,0104579306",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,"-2,37",Neutral,0,Damaging,"32,15","14,52"
"inspected, many artifacts",UPN2_048,11,119149286,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp432Tyr/c.1294G>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),2105,74,2181,"0,0339293902",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,45",Deleterious,"0,053",Tolerated,"33,54","33,38"
"low bq, low freq, many artifacts, many samples",UPN2_044,11,119149303,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg437Ser/c.1311A>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),3601,41,3659,"0,0112052473",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-3,Deleterious,49,Damaging,"32,74","20,24"
"low bq, low freq, many artifacts, many samples",UPN2_048,11,119149303,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg437Ser/c.1311A>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),2145,22,2186,"0,0100640439",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-3,Deleterious,49,Damaging,"32,43","16,32"
"low bq, low freq, many artifacts, many samples",UPN2_050,11,119149303,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg437Ser/c.1311A>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),19342,199,19624,"0,0101406441",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-3,Deleterious,49,Damaging,"32,59","19,52"
"low bq, low freq, many artifacts, many samples",UPN2_044,11,119149307,A,T,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser439Cys/c.1315A>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),3609,40,3663,"0,0109200109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,94",Neutral,33,Damaging,"33,45","15,65"
"low bq, low freq, many artifacts, many samples",UPN2_048,11,119149332,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala447Glu/c.1340C>A|906|CBL|protein_coding|CODING|ENST00000264033|9|A),2114,37,2186,"0,016925892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,278,Tolerated,31,"22,97"
"low bq, low freq, many artifacts, many samples",UPN2_047,11,119149335,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu448Val/c.1343A>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),10623,122,10787,"0,0113099101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,12,Damaging,"33,46","17,75"
"low bq, low freq, many artifacts, many samples",UPN2_001,11,119149338,G,T,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly449Val/c.1346G>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),6355,67,6429,"0,0104215275",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,63,Tolerated,"32,8","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_045,11,119149352,A,T,missense_variant(MODERATE|MISSENSE|Aat/Tat|p.Asn454Tyr/c.1360A>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),9606,108,9750,"0,0110769231",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,05",Neutral,48,Damaging,"33,6","17,82"
"low bq, low freq, many artifacts",UPN2_057,11,119149352,A,T,missense_variant(MODERATE|MISSENSE|Aat/Tat|p.Asn454Tyr/c.1360A>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),11748,122,11929,"0,0102271775",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,05",Neutral,48,Damaging,"33,56","17,22"
"low bq, low freq, many artifacts, many samples",UPN2_042,11,119149353,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn454Ile/c.1361A>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),8759,97,8886,"0,0109160477",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,184,Tolerated,"33,24",16
"low bq, low freq, many artifacts, many samples",UPN2_045,11,119149353,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn454Ile/c.1361A>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),9615,99,9749,"0,0101548877",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,184,Tolerated,"33,12","16,29"
"low bq, low freq, many artifacts, many samples",UPN2_051,11,119149353,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn454Ile/c.1361A>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),8257,85,8373,"0,010151678",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,184,Tolerated,"33,25","17,24"
"low bq, low freq, many artifacts, many samples",UPN2_052,11,119149353,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn454Ile/c.1361A>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),7931,84,8042,"0,0104451629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,184,Tolerated,"33,01","16,33"
"low bq, low freq, many artifacts, many samples",UPN2_054,11,119149353,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn454Ile/c.1361A>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),6800,83,6900,"0,0120289855",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,184,Tolerated,"33,02","19,36"
"low bq, low freq, many artifacts, many samples",UPN2_057,11,119149353,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn454Ile/c.1361A>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),11768,121,11929,"0,0101433481",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,184,Tolerated,"33,22","16,8"
"low bq, low freq, many artifacts",UPN2_058,11,119149353,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn454Ile/c.1361A>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),14664,154,14869,"0,0103571188",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,184,Tolerated,"33,21","17,64"
"ATG repeat, many samples, low freq",UPN2_001,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),6170,205,6437,"0,0318471338",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,15",NA
"ATG repeat, many samples, low freq",UPN2_014,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),7096,195,7332,"0,0265957447",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,42",NA
"ATG repeat, many samples, low freq",UPN2_015,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),9095,233,9416,"0,0247451147",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,53",NA
"ATG repeat, many samples, low freq",UPN2_016,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),4540,118,4695,"0,0251331203",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,56",NA
"ATG repeat, many samples, low freq",UPN2_017,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),3123,86,3241,"0,0265350201",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,46",NA
"ATG repeat, many samples, low freq",UPN2_018,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),4884,123,5047,"0,0243709134",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,56",NA
"ATG repeat, many samples, low freq",UPN2_019,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),6032,169,6250,"0,02704",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,59",NA
"ATG repeat, many samples, low freq",UPN2_020,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),4174,105,4320,"0,0243055556",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,58",NA
"ATG repeat, many samples, low freq",UPN2_021,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),5495,125,5680,"0,0220070423",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,61",NA
"ATG repeat, many samples, low freq",UPN2_002,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),8700,254,9021,"0,0281565237",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,15",NA
"ATG repeat, many samples, low freq",UPN2_003,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),1578,59,1646,"0,0358444714",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"33,99",NA
"ATG repeat, many samples, low freq",UPN2_022,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),7286,170,7512,"0,0226304579",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,48",NA
"ATG repeat, many samples, low freq",UPN2_023,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),7763,222,8038,"0,0276188106",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,41",NA
"ATG repeat, many samples, low freq",UPN2_024,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),3503,94,3617,"0,0259883882",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,46",NA
"ATG repeat, many samples, low freq",UPN2_025,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),8464,215,8741,"0,0245967281",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,46",NA
"ATG repeat, many samples, low freq",UPN2_026,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),7876,186,8137,"0,0228585474",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,47",NA
"ATG repeat, many samples, low freq",UPN2_004,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),989,20,1014,"0,0197238659",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,18",NA
"ATG repeat, many samples, low freq",UPN2_027,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),9372,266,9720,"0,0273662551",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,52",NA
"ATG repeat, many samples, low freq",UPN2_089,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),6406,160,6612,"0,0241984271",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"35,01",NA
"ATG repeat, many samples, low freq",UPN2_042,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),8562,220,8890,"0,0247469066",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"33,84",NA
"ATG repeat, many samples, low freq",UPN2_028,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),6388,158,6594,"0,0239611768",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,32",NA
"ATG repeat, many samples, low freq",UPN2_043,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),7538,165,7803,"0,0211457132",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"33,82",NA
"ATG repeat, many samples, low freq",UPN2_044,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),1776,33,1823,"0,0181020296",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"33,83",NA
"ATG repeat, many samples, low freq",UPN2_029,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),7862,230,8167,"0,0281621158",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,53",NA
"ATG repeat, many samples, low freq",UPN2_030,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),7710,217,7979,"0,0271963905",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,51",NA
"ATG repeat, many samples, low freq",UPN2_031,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),4815,129,4983,"0,0258880193",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,53",NA
"ATG repeat, many samples, low freq",UPN2_005,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),2394,83,2494,"0,0332798717",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,04",NA
"ATG repeat, many samples, low freq",UPN2_045,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),9339,259,9754,"0,0265532089",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"33,71",NA
"ATG repeat, many samples, low freq",UPN2_032,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),3007,75,3102,"0,0241779497",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,26",NA
"ATG repeat, many samples, low freq",UPN2_046,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),9741,260,10108,"0,0257222002",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"33,72",NA
"ATG repeat, many samples, low freq",UPN2_033,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),5478,136,5663,"0,0240155395",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,48",NA
"ATG repeat, many samples, low freq",UPN2_034,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),2137,65,2224,"0,0292266187",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,54",NA
"ATG repeat, many samples, low freq",UPN2_047,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),10412,254,10783,"0,0235555968",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"33,79",NA
"ATG repeat, many samples, low freq",UPN2_048,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),1048,32,1091,"0,0293308891",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"33,76",NA
"ATG repeat, many samples, low freq",UPN2_035,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),9008,213,9299,"0,0229056888",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,55",NA
"ATG repeat, many samples, low freq",UPN2_036,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),8289,211,8550,"0,0246783626",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,46",NA
"inspected, ATG repeat, many samples, low freq",UPN2_006,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),4434,140,4608,"0,0303819444",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,12",NA
"ATG repeat, many samples, low freq",UPN2_049,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),7191,191,7473,"0,0255586779",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"33,59",NA
"ATG repeat, many samples, low freq",UPN2_050,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),9436,220,9749,"0,0225664171",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"33,54",NA
"ATG repeat, many samples, low freq",UPN2_037,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),11260,294,11637,"0,0252642434",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,5",NA
"ATG repeat, many samples, low freq",UPN2_051,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),8101,170,8377,"0,0202936612",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"33,67",NA
"ATG repeat, many samples, low freq",UPN2_052,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),7782,164,8044,"0,0203878667",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"33,69",NA
"ATG repeat, many samples, low freq",UPN2_038,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),13825,320,14243,"0,0224671769",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,46",NA
"ATG repeat, many samples, low freq",UPN2_039,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),6993,174,7233,"0,0240564081",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,34",NA
"ATG repeat, many samples, low freq",UPN2_053,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),10577,299,10996,"0,0271917061",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"33,59",NA
"ATG repeat, many samples, low freq",UPN2_054,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),6689,135,6905,"0,01955105",0,0,0,1,1,0,1,1,4,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"33,58",NA
"ATG repeat, many samples, low freq",UPN2_007,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),18132,537,18808,"0,0285516801",0,0,0,1,1,0,1,1,4,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,13",NA
"ATG repeat, many samples, low freq",UPN2_008,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),24415,706,25350,"0,0278500986",0,0,0,1,1,0,1,1,4,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,14",NA
"ATG repeat, many samples, low freq",UPN2_009,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),18754,490,19416,"0,025236918",0,0,0,1,1,0,1,1,4,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,12",NA
"ATG repeat, many samples, low freq",UPN2_010,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),12713,389,13207,"0,0294540774",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,15",NA
"ATG repeat, many samples, low freq",UPN2_011,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),15318,422,15903,"0,0265358737",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,17",NA
"ATG repeat, many samples, low freq",UPN2_055,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),10660,263,11062,"0,0237750859",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"33,67",NA
"inspected, ATG repeat, many samples, low freq",UPN2_056,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),1715,39,1776,"0,0219594595",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"33,75",NA
"ATG repeat, many samples, low freq",UPN2_090,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),4196,128,4342,"0,0294795025",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,91",NA
"ATG repeat, many samples, low freq",UPN2_057,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),11483,296,11936,"0,0247989276",0,0,0,1,1,0,1,1,4,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"33,69",NA
"ATG repeat, many samples, low freq",UPN2_058,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),14339,367,14883,"0,0246590069",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"33,75",NA
"ATG repeat, many samples, low freq",UPN2_059,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),3729,161,3916,"0,041113381",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,11",NA
"ATG repeat, many samples, low freq",UPN2_012,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),7754,224,8049,"0,027829544",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,1",NA
"ATG repeat, many samples, low freq",UPN2_060,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),5240,136,5418,"0,0251015135",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"33,96",NA
"ATG repeat, many samples, low freq",UPN2_040,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),6159,174,6392,"0,0272215269",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,44",NA
"ATG repeat, many samples, low freq",UPN2_013,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),4802,153,4998,"0,0306122449",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,09",NA
"ATG repeat, many samples, low freq",UPN2_091,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),4632,145,4794,"0,030246141",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"35,06",NA
"ATG repeat, many samples, low freq",UPN2_092,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),3568,133,3721,"0,0357430798",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,89",NA
"ATG repeat, many samples, low freq",UPN2_093,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),4361,94,4476,"0,0210008937",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,99",NA
"ATG repeat, many samples, low freq",UPN2_061,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),5609,187,5846,"0,0319876839",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,06",NA
"ATG repeat, many samples, low freq",UPN2_062,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),4906,147,5087,"0,0288971889",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,12",NA
"ATG repeat, many samples, low freq",UPN2_063,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),5603,173,5811,"0,0297711237",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,02",NA
"ATG repeat, many samples, low freq",UPN2_064,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),4386,156,4577,"0,0340834608",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,34,NA
"ATG repeat, many samples, low freq",UPN2_065,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),6101,188,6348,"0,029615627",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,19",NA
"ATG repeat, many samples, low freq",UPN2_066,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),7168,228,7444,"0,0306286943",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,12",NA
"ATG repeat, many samples, low freq",UPN2_067,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),7411,240,7699,"0,0311728796",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,15",NA
"ATG repeat, many samples, low freq",UPN2_068,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),5870,185,6099,"0,0303328414",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,1",NA
"ATG repeat, many samples, low freq",UPN2_069,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),5899,163,6101,"0,0267169317",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,14",NA
"ATG repeat, many samples, low freq",UPN2_070,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),4224,129,4387,"0,0294050604",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,17",NA
"ATG repeat, many samples, low freq",UPN2_071,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),3433,138,3592,"0,0384187082",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,02",NA
"ATG repeat, many samples, low freq",UPN2_072,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),3968,130,4129,"0,031484621",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,17",NA
"ATG repeat, many samples, low freq",UPN2_073,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),3372,143,3542,"0,0403726708",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,34,NA
"ATG repeat, many samples, low freq",UPN2_074,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),4133,134,4299,"0,0311700395",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"33,96",NA
"ATG repeat, many samples, low freq",UPN2_075,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),4811,170,5020,"0,0338645418",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,01",NA
"ATG repeat, many samples, low freq",UPN2_076,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),4828,142,5006,"0,0283659608",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,05",NA
"ATG repeat, many samples, low freq",UPN2_077,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),6460,241,6752,"0,035693128",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,07",NA
"ATG repeat, many samples, low freq",UPN2_078,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),5949,162,6141,"0,0263800684",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"33,9",NA
"ATG repeat, many samples, low freq",UPN2_079,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),3657,97,3770,"0,025729443",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"33,99",NA
"ATG repeat, many samples, low freq",UPN2_080,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),4500,122,4646,"0,0262591477",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,09",NA
"ATG repeat, many samples, low freq",UPN2_081,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),5373,185,5599,"0,0330416146",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,22",NA
"ATG repeat, many samples, low freq",UPN2_082,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),7601,204,7856,"0,0259674134",0,0,0,1,1,0,1,1,4,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,14",NA
"ATG repeat, many samples, low freq",UPN2_083,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),6708,222,6974,"0,0318325208",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"33,99",NA
"ATG repeat, many samples, low freq",UPN2_084,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),7765,236,8042,"0,0293459338",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,1",NA
"ATG repeat, many samples, low freq",UPN2_085,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),5883,204,6134,"0,0332572546",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,12",NA
"ATG repeat, many samples, low freq",UPN2_086,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),4481,135,4640,"0,0290948276",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"33,95",NA
"ATG repeat, many samples, low freq",UPN2_087,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),8103,279,8450,"0,0330177515",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,08",NA
"ATG repeat, many samples, low freq",UPN2_088,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),6224,169,6457,"0,0261731454",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,09",NA
"ATG repeat, many samples, low freq",UPN2_094,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),6233,190,6465,"0,0293890178",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"35,07",NA
"ATG repeat, many samples, low freq",UPN2_095,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),5819,155,6002,"0,0258247251",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,99",NA
"ATG repeat, many samples, low freq",UPN2_096,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),5781,176,5985,"0,0294068505",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"35,08",NA
"ATG repeat, many samples, low freq",UPN2_097,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),6313,196,6549,"0,0299282333",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"35,01",NA
"ATG repeat, many samples, low freq",UPN2_098,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),5070,127,5217,"0,0243434924",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"35,01",NA
"ATG repeat, many samples, low freq",UPN2_099,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),3269,99,3378,"0,0293072824",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,94",NA
"ATG repeat, many samples, low freq",UPN2_100,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),4872,129,5016,"0,0257177033",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"35,06",NA
"ATG repeat, many samples, low freq",UPN2_101,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),5553,155,5737,"0,027017605",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"35,04",NA
"ATG repeat, many samples, low freq",UPN2_102,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),6234,174,6451,"0,0269725624",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,97",NA
"ATG repeat, many samples, low freq",UPN2_103,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),5556,152,5732,"0,0265177948",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,93",NA
"ATG repeat, many samples, low freq",UPN2_104,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),6508,182,6720,"0,0270833333",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,95",NA
"ATG repeat, many samples, low freq",UPN2_105,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),5121,138,5285,"0,0261116367",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,94",NA
"ATG repeat, many samples, low freq",UPN2_106,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),5926,201,6154,"0,0326616835",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,99",NA
"ATG repeat, many samples, low freq",UPN2_107,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),10309,284,10644,"0,0266816986",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,93",NA
"ATG repeat, many samples, low freq",UPN2_108,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),8795,190,9032,"0,0210363153",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"35,01",NA
"ATG repeat, many samples, low freq",UPN2_109,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),8018,212,8258,"0,0256720756",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,94",NA
"ATG repeat, many samples, low freq",UPN2_110,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),7923,207,8161,"0,0253645387",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"34,93",NA
"ATG repeat, many samples, low freq",UPN2_111,11,119149355,TATG,T,disruptive_inframe_deletion(MODERATE||gatgaa/gaa|p.Asp460del/c.1380_1382delTGA|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),7335,167,7535,"0,0221632382",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,-3,Deleterious,NA,NA,"35,05",NA
"low freq, many artifacts, many samples",UPN2_015,11,119149358,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp456Tyr/c.1366G>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),9038,115,9169,"0,012542262",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,06",Deleterious,1,Damaging,"34,61","28,56"
"low freq, many artifacts, many samples",UPN2_020,11,119149358,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp456Tyr/c.1366G>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),4145,53,4204,"0,0126070409",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,06",Deleterious,1,Damaging,"34,77","28,96"
"low freq, many artifacts, many samples",UPN2_002,11,119149358,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp456Tyr/c.1366G>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),8626,115,8750,"0,0131428571",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,06",Deleterious,1,Damaging,"34,07","27,2"
"low freq, many artifacts, many samples",UPN2_024,11,119149358,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp456Tyr/c.1366G>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),3471,41,3518,"0,0116543491",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,06",Deleterious,1,Damaging,"34,73","30,37"
"low freq, many artifacts, many samples",UPN2_025,11,119149358,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp456Tyr/c.1366G>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),8387,101,8507,"0,0118725755",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,06",Deleterious,1,Damaging,"34,55","28,08"
"low freq, many artifacts, many samples",UPN2_026,11,119149358,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp456Tyr/c.1366G>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),7826,103,7941,"0,0129706586",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,06",Deleterious,1,Damaging,"34,6","29,83"
"low freq, many artifacts, many samples",UPN2_027,11,119149358,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp456Tyr/c.1366G>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),9305,117,9437,"0,0123980078",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,06",Deleterious,1,Damaging,"34,55","29,84"
"low bq, low freq, many artifacts, many samples",UPN2_042,11,119149358,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp456Tyr/c.1366G>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),8520,114,8654,"0,0131730991",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,06",Deleterious,1,Damaging,"33,54","25,81"
"low bq, low freq, many artifacts, many samples",UPN2_043,11,119149358,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp456Tyr/c.1366G>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),7490,109,7615,"0,0143138542",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,06",Deleterious,1,Damaging,"33,71","25,62"
"low freq, many artifacts, many samples",UPN2_029,11,119149358,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp456Tyr/c.1366G>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),7812,105,7929,"0,0132425274",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,06",Deleterious,1,Damaging,"34,61","29,76"
"low freq, many artifacts, many samples",UPN2_046,11,119149358,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp456Tyr/c.1366G>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),9696,139,9848,"0,014114541",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,06",Deleterious,1,Damaging,"33,67","27,7"
"low freq, many artifacts, many samples",UPN2_034,11,119149358,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp456Tyr/c.1366G>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),2127,26,2156,"0,0120593692",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,06",Deleterious,1,Damaging,"34,41","28,92"
"low bq, low freq, many artifacts, many samples",UPN2_047,11,119149358,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp456Tyr/c.1366G>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),10336,172,10522,"0,0163467021",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,06",Deleterious,1,Damaging,"33,63","25,4"
"low freq, many artifacts, many samples",UPN2_006,11,119149358,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp456Tyr/c.1366G>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),4406,51,4464,"0,0114247312",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,06",Deleterious,1,Damaging,"33,93","29,57"
"low bq, low freq, many artifacts, many samples",UPN2_053,11,119149358,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp456Tyr/c.1366G>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),10508,160,10690,"0,0149672591",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,06",Deleterious,1,Damaging,"33,5","24,58"
"low bq, low freq, many artifacts, many samples",UPN2_010,11,119149358,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp456Tyr/c.1366G>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),12586,164,12801,"0,0128114991",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,06",Deleterious,1,Damaging,"33,99","25,55"
"low bq, low freq, many artifacts, many samples",UPN2_055,11,119149358,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp456Tyr/c.1366G>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),10616,150,10790,"0,0139017609",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,06",Deleterious,1,Damaging,"33,53","24,92"
"low bq, low freq, many artifacts, many samples",UPN2_058,11,119149358,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp456Tyr/c.1366G>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),14255,219,14495,"0,0151086582",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,06",Deleterious,1,Damaging,"33,6","25,52"
"low freq, many artifacts, many samples",UPN2_012,11,119149358,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp456Tyr/c.1366G>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),7707,90,7814,"0,0115177886",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,06",Deleterious,1,Damaging,"34,11","27,43"
"low bq, low freq, many artifacts, many samples",UPN2_060,11,119149358,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp456Tyr/c.1366G>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),5192,73,5271,"0,0138493644",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,06",Deleterious,1,Damaging,"33,72",25
"low bq, low freq, many artifacts, many samples",UPN2_013,11,119149358,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp456Tyr/c.1366G>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),4765,71,4840,"0,0146694215",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,06",Deleterious,1,Damaging,"33,98","26,8"
"low freq, many artifacts, many samples",UPN2_063,11,119149358,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp456Tyr/c.1366G>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),5545,75,5631,"0,0133191263",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,06",Deleterious,1,Damaging,"33,95","27,05"
"low freq, many artifacts, many samples",UPN2_064,11,119149358,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp456Tyr/c.1366G>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),4351,57,4410,"0,0129251701",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,06",Deleterious,1,Damaging,"33,86","28,75"
"low bq, low freq, many artifacts, many samples",UPN2_066,11,119149358,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp456Tyr/c.1366G>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),7094,99,7208,"0,0137347392",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,06",Deleterious,1,Damaging,"33,9","26,97"
"low bq, low freq, many artifacts, many samples",UPN2_069,11,119149358,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp456Tyr/c.1366G>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),5821,99,5930,"0,0166947723",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,06",Deleterious,1,Damaging,"33,93","25,91"
"low freq, many artifacts, many samples",UPN2_070,11,119149358,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp456Tyr/c.1366G>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),4196,50,4252,"0,0117591722",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,06",Deleterious,1,Damaging,"33,95","27,66"
"low bq, low freq, many artifacts, many samples",UPN2_074,11,119149358,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp456Tyr/c.1366G>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),4096,56,4160,"0,0134615385",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,06",Deleterious,1,Damaging,"33,91","26,61"
"low freq, many artifacts, many samples",UPN2_075,11,119149358,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp456Tyr/c.1366G>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),4766,78,4849,"0,0160857909",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,06",Deleterious,1,Damaging,"33,9","29,19"
"low freq, many artifacts, many samples",UPN2_077,11,119149358,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp456Tyr/c.1366G>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),6392,96,6498,"0,0147737765",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,06",Deleterious,1,Damaging,"34,08","28,69"
"low freq, many artifacts, many samples",UPN2_078,11,119149358,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp456Tyr/c.1366G>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),5876,83,5976,"0,0138888889",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,06",Deleterious,1,Damaging,"33,82","27,53"
"low bq, low freq, many artifacts, many samples",UPN2_079,11,119149358,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp456Tyr/c.1366G>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),3615,53,3672,"0,0144335512",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,06",Deleterious,1,Damaging,"33,98","26,6"
"low freq, many artifacts, many samples",UPN2_080,11,119149358,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp456Tyr/c.1366G>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),4461,60,4526,"0,0132567388",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,06",Deleterious,1,Damaging,"33,93",27
"low freq, many artifacts, many samples",UPN2_081,11,119149358,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp456Tyr/c.1366G>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),5332,65,5400,"0,012037037",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,06",Deleterious,1,Damaging,"33,83","29,6"
"low bq, low freq, many artifacts, many samples",UPN2_083,11,119149358,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp456Tyr/c.1366G>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),6639,92,6742,"0,0136458024",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,06",Deleterious,1,Damaging,"33,91","25,88"
"low bq, low freq, many artifacts, many samples",UPN2_084,11,119149358,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp456Tyr/c.1366G>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),7690,99,7802,"0,0126890541",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,06",Deleterious,1,Damaging,"33,89","25,79"
"low freq, many artifacts, many samples",UPN2_085,11,119149358,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp456Tyr/c.1366G>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),5830,87,5921,"0,0146934639",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,06",Deleterious,1,Damaging,"33,94","27,01"
"low bq, low freq, many artifacts, many samples",UPN2_086,11,119149358,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp456Tyr/c.1366G>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),4437,57,4505,"0,0126526082",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,06",Deleterious,1,Damaging,"33,88","24,4"
"low freq, many artifacts",UPN2_087,11,119149358,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp456Tyr/c.1366G>T|906|CBL|protein_coding|CODING|ENST00000264033|9|T),8040,100,8160,"0,012254902",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,06",Deleterious,1,Damaging,"33,96","27,66"
" strandbias, many samples",UPN2_001,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),13275,910,14232,"0,063940416",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"33,22","31,68"
many samples,UPN2_014,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),16045,829,16935,"0,0489518748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,211,Tolerated,"33,27","31,53"
" strandbias, many samples",UPN2_015,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),21307,768,22155,"0,0346648612",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"33,28","31,65"
" strandbias, many samples",UPN2_016,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),10690,511,11238,"0,0454707243",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"33,23","31,58"
" strandbias, many samples",UPN2_017,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),7079,369,7468,"0,0494108195",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"33,32","31,59"
many samples,UPN2_018,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),11343,539,11916,"0,0452332998",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,211,Tolerated,"33,25","31,69"
many samples,UPN2_019,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),13429,677,14163,"0,0478006072",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,211,Tolerated,"33,3","31,55"
many samples,UPN2_020,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),9963,548,10544,"0,0519726859",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,211,Tolerated,"33,22","31,52"
" strandbias, many samples",UPN2_021,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),12015,680,12728,"0,0534255185",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"33,39","31,52"
" strandbias, many samples",UPN2_002,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),17342,1219,18627,"0,065442637",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"33,42","31,47"
" strandbias, many samples",UPN2_003,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),3212,173,3397,"0,0509272888",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"33,26","31,56"
" strandbias, many samples",UPN2_022,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),17622,917,18603,"0,0492931248",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"33,2","31,61"
many samples,UPN2_023,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),18083,831,18978,"0,0437875435",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,211,Tolerated,"33,27","31,57"
many samples,UPN2_024,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),8142,344,8516,"0,0403945514",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,211,Tolerated,"33,32","31,57"
" strandbias, many samples",UPN2_025,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),19525,794,20381,"0,0389578529",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"33,22","31,36"
" strandbias, many samples",UPN2_026,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),19205,997,20281,"0,0491593117",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"33,21","31,52"
many samples,UPN2_004,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),2141,161,2312,"0,0696366782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,211,Tolerated,"33,19","31,82"
" strandbias, many samples",UPN2_027,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),21365,1143,22565,"0,0506536672",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"33,3","31,69"
" strandbias, many samples",UPN2_042,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),18644,391,19109,"0,0204615626",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"33,04","30,9"
many samples,UPN2_028,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),16001,868,16941,"0,0512366448",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,211,Tolerated,"33,13","31,73"
" strandbias, many samples",UPN2_043,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),17625,412,18101,"0,0227611734",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"32,94","31,24"
"inspected, strandbias, many samples",UPN2_044,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),6340,224,6590,"0,0339908953",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"32,45","31,42"
" strandbias, many samples",UPN2_029,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),19472,1088,20620,"0,0527643065",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"33,19","31,6"
" strandbias, many samples",UPN2_030,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),17368,881,18310,"0,0481157837",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"33,31","31,53"
" strandbias, many samples",UPN2_031,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),10918,441,11395,"0,0387011847",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"33,33","31,45"
many samples,UPN2_005,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),5202,408,5632,"0,0724431818",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,211,Tolerated,"33,27","31,35"
" strandbias, many samples",UPN2_045,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),20601,231,20902,"0,011051574",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"32,97","30,92"
"inspected, strandbias, many samples",UPN2_032,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),7782,406,8207,"0,0494699647",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"33,09","31,55"
" strandbias, many samples",UPN2_046,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),24959,835,25893,"0,0322480979",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"32,81","31,27"
many samples,UPN2_033,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),13239,608,13905,"0,0437252787",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,211,Tolerated,"33,21","31,68"
many samples,UPN2_034,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),5303,245,5570,"0,0439856373",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,211,Tolerated,"33,22","31,64"
" strandbias, many samples",UPN2_047,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),22052,500,22627,"0,0220974941",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"33,05","30,95"
many samples,UPN2_048,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),1833,60,1901,"0,0315623356",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,211,Tolerated,"33,28","31,52"
" strandbias, many samples",UPN2_035,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),21504,1211,22771,"0,0531816785",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"33,2","31,59"
" strandbias, many samples",UPN2_036,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),20058,1096,21206,"0,0516834858",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"33,19","31,52"
" strandbias, many samples",UPN2_006,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),10527,851,11411,"0,0745771624",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"33,17","31,48"
" strandbias, many samples",UPN2_049,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),17115,394,17593,"0,0223952708",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"32,88","30,94"
" strandbias, many samples",UPN2_037,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),25969,1180,27252,"0,0432995743",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"33,29","31,6"
" strandbias, many samples",UPN2_051,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),20337,327,20758,"0,0157529627",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"32,82","31,31"
" strandbias, many samples",UPN2_038,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),30629,1623,32358,"0,0501576117",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"33,32","31,5"
many samples,UPN2_039,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),16196,933,17169,"0,0543421283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,211,Tolerated,"33,28","31,75"
" strandbias, many samples",UPN2_053,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),25609,629,26338,"0,0238818437",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"32,87","31,3"
"low freq, many artifacts, many samples",UPN2_054,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),17546,302,17923,"0,0168498577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,211,Tolerated,"32,79","31,35"
" strandbias, many samples",UPN2_007,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),38967,2446,41562,"0,0588518358",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"33,22","31,55"
" strandbias, many samples",UPN2_008,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),49258,2719,52179,"0,052109086",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"33,35","31,61"
" strandbias, many samples",UPN2_009,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),38920,1857,40912,"0,0453901056",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"33,26","31,4"
many samples,UPN2_010,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),28815,1775,30691,"0,0578345443",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,211,Tolerated,"33,15","31,43"
" strandbias, many samples",UPN2_011,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),35072,2406,37583,"0,0640183061",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"33,13","31,55"
" strandbias, many samples",UPN2_055,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),25820,545,26475,"0,020585458",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"32,86","31,17"
"low freq, many artifacts, many samples",UPN2_056,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),3266,46,3324,"0,0138387485",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,211,Tolerated,"33,16","30,98"
" strandbias, many samples",UPN2_057,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),29740,812,30671,"0,0264745199",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"32,78","31,24"
" strandbias, many samples",UPN2_058,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),35021,1382,36555,"0,0378060457",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"32,84","31,32"
many samples,UPN2_059,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),9006,475,9515,"0,0499211771",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,211,Tolerated,"32,91","31,24"
" strandbias, many samples",UPN2_012,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),16604,1048,17714,"0,0591622446",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"33,18","31,44"
" strandbias, many samples",UPN2_060,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),17970,1411,19419,"0,0726607961",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"32,48","31,23"
" strandbias, many samples",UPN2_040,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),15428,811,16298,"0,0497607068",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"33,17","31,57"
" strandbias, many samples",UPN2_013,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),10153,642,10830,"0,0592797784",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"33,23","31,5"
" strandbias, many samples",UPN2_091,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),11386,145,11551,"0,0125530257",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"33,1","30,92"
"low freq, many artifacts, many samples",UPN2_093,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),10909,126,11073,"0,0113790301",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,211,Tolerated,"33,05","31,43"
many samples,UPN2_061,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),18586,1542,20188,"0,0763820091",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,211,Tolerated,"32,54","31,43"
" strandbias, many samples",UPN2_062,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),17921,1592,19582,"0,0812991523",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"32,47","31,53"
" strandbias, many samples",UPN2_063,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),18091,1706,19875,"0,085836478",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"32,54","31,39"
" strandbias, many samples",UPN2_064,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),10868,831,11753,"0,0707053518",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"32,82","31,37"
" strandbias, many samples",UPN2_065,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),14403,758,15216,"0,0498159832",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"32,83","31,13"
" strandbias, many samples",UPN2_066,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),21582,1460,23133,"0,0631133013",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"32,63","31,31"
" strandbias, many samples",UPN2_067,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),20722,1412,22195,"0,063617932",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"32,68","31,25"
many samples,UPN2_068,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),16501,1066,17628,"0,0604719764",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,211,Tolerated,"32,7","31,33"
many samples,UPN2_069,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),18037,1330,19432,"0,068443804",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,211,Tolerated,"32,62","31,36"
many samples,UPN2_070,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),13459,985,14509,"0,0678888965",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,211,Tolerated,"32,56","31,4"
many samples,UPN2_071,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),11973,1053,13064,"0,0806031843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,211,Tolerated,"32,48","31,45"
" strandbias, many samples",UPN2_072,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),14311,1178,15556,"0,0757264078",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"32,49","31,43"
many samples,UPN2_073,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),8782,593,9409,"0,0630247635",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,211,Tolerated,"32,71","31,34"
" strandbias, many samples",UPN2_074,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),10579,703,11319,"0,0621079601",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"32,77","31,4"
" strandbias, many samples",UPN2_075,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),14286,1084,15420,"0,0702983139",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"32,65","31,42"
" strandbias, many samples",UPN2_076,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),16561,1323,17930,"0,0737869492",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"32,55","31,38"
" strandbias, many samples",UPN2_077,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),17628,1190,18873,"0,0630530387",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"32,73","31,26"
" strandbias, many samples",UPN2_078,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),17476,1371,18889,"0,072581926",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"32,69","31,35"
many samples,UPN2_079,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),11131,871,12047,"0,0723001577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,211,Tolerated,"32,61","31,61"
many samples,UPN2_080,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),15663,1374,17098,"0,0803602761",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,211,Tolerated,"32,48","31,49"
many samples,UPN2_081,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),13907,880,14826,"0,0593551868",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,211,Tolerated,"32,81","31,29"
" strandbias, many samples",UPN2_082,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),20298,1212,21585,"0,0561501042",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"32,73","31,21"
" strandbias, many samples",UPN2_083,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),19882,1536,21493,"0,0714651282",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"32,63","31,51"
" strandbias, many samples",UPN2_084,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),25000,1759,26849,"0,0655145443",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"32,57","31,51"
" strandbias, many samples",UPN2_085,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),17223,1131,18414,"0,0614206582",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"32,69","31,19"
many samples,UPN2_086,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),12606,812,13450,"0,0603717472",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,211,Tolerated,"32,65","31,51"
" strandbias, many samples",UPN2_087,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),20872,1301,22274,"0,0584089072",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"32,81","31,28"
" strandbias, many samples",UPN2_088,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),17846,1275,19188,"0,0664477799",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"32,63","31,23"
" strandbias, many samples",UPN2_095,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),13886,147,14068,"0,0104492465",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"33,2","31,27"
"low freq, many artifacts",UPN2_097,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),13976,145,14158,"0,0102415595",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,211,Tolerated,"33,28","30,45"
"inspected, strandbias, many samples",UPN2_098,11,119149376,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg462Gly/c.1384C>G|906|CBL|protein_coding|CODING|ENST00000264033|9|G),12940,138,13105,"0,0105303319",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,211",Tolerated,"33,07","30,92"
"low freq, many artifacts",UPN2_056,11,119149385,GA,G,frameshift_variant(HIGH||gat/|p.Asp465fs/c.1394delA|906|CBL|protein_coding|CODING|ENST00000264033|9|G),3286,39,3355,"0,0116244411",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,1",NA
"low freq, many artifacts",UPN2_048,11,119149414,T,TG,frameshift_variant(HIGH||ggt/ggGt|p.Ala476fs/c.1424dupG|906|CBL|protein_coding|CODING|ENST00000264033|9|TG|INFO_REALIGN_3_PRIME),1914,25,1928,"0,012966805",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,78",NA
"low freq, many artifacts",UPN2_081,11,119149414,TG,T,frameshift_variant(HIGH||ggt/|p.Gly475fs/c.1424delG|906|CBL|protein_coding|CODING|ENST00000264033|9|T|INFO_REALIGN_3_PRIME),15134,156,15340,"0,0101694915",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,82",NA
"low freq, many artifacts",UPN2_044,12,11803062,A,G,start_lost(HIGH|MISSENSE|Atg/Gtg|p.Met1?/c.1A>G|452|ETV6|protein_coding|CODING|ENST00000396373|1|G),1803,20,1825,"0,0109589041",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,23",Neutral,0,Damaging,"35,73",36
"low freq, many artifacts",UPN2_060,12,11803068,G,A,missense_variant(MODERATE|MISSENSE|Gag/Aag|p.Glu3Lys/c.7G>A|452|ETV6|protein_coding|CODING|ENST00000396373|1|A),1293,22,1316,"0,0167173252",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,"0,039",Damaging,"35,26","34,82"
"low freq, many artifacts",UPN2_048,12,11803083,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys8Arg/c.22T>C|452|ETV6|protein_coding|CODING|ENST00000396373|1|C),4117,47,4183,"0,0112359551",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,63",Tolerated,"35,3","35,81"
"low freq, many artifacts",UPN2_092,12,11905393,A,G,missense_variant(MODERATE|MISSENSE|Att/Gtt|p.Ile15Val/c.43A>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),2528,31,2560,"0,012109375",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,16",Neutral,"0,526",Tolerated,"35,48","35,29"
"low freq, many artifacts",UPN2_032,12,11905397,C,T,missense_variant(MODERATE|MISSENSE|tCa/tTa|p.Ser16Leu/c.47C>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),5055,52,5110,"0,0101761252",0,0,0,0,0,0,0,1,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,01",Neutral,5,Damaging,"35,45","34,77"
"low freq, many artifacts",UPN2_041,12,11905400,A,T,missense_variant(MODERATE|MISSENSE|tAt/tTt|p.Tyr17Phe/c.50A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),9520,124,9686,"0,0128019822",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,29",Neutral,"0,798",Tolerated,"35,32","33,73"
"low bq, low freq, many artifacts, many samples",UPN2_028,12,11905414,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser22Arg/c.64A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),2477,26,2516,"0,0103338633",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,5,Damaging,"30,22","19,88"
"low bq, low freq, many artifacts, many samples",UPN2_048,12,11905414,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser22Arg/c.64A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),3229,34,3298,"0,0103092784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,5,Damaging,"30,74","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_017,12,11905441,A,C,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr31Pro/c.91A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),2277,30,2317,"0,0129477773",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,46",Neutral,"0,15",Tolerated,"27,42",14
"low bq, low freq, many artifacts, many samples",UPN2_041,12,11905441,A,C,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr31Pro/c.91A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),2909,35,2957,"0,0118363206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,46",Neutral,"0,15",Tolerated,"27,9","15,51"
"low bq, low freq, many artifacts, many samples",UPN2_042,12,11905441,A,C,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr31Pro/c.91A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),9493,119,9658,"0,0123213916",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,46",Neutral,"0,15",Tolerated,"28,23","15,58"
"low bq, low freq, many artifacts, many samples",UPN2_045,12,11905441,A,C,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr31Pro/c.91A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),8854,93,9000,"0,0103333333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,46",Neutral,"0,15",Tolerated,"27,85","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_046,12,11905441,A,C,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr31Pro/c.91A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),5734,67,5826,"0,0115001716",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,46",Neutral,"0,15",Tolerated,"27,93","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_047,12,11905441,A,C,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr31Pro/c.91A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),8405,98,8544,"0,0114700375",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,46",Neutral,"0,15",Tolerated,"28,04","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_050,12,11905441,A,C,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr31Pro/c.91A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),4804,50,4880,"0,0102459016",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,46",Neutral,"0,15",Tolerated,"28,38","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_055,12,11905441,A,C,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr31Pro/c.91A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),8038,89,8167,"0,0108975144",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,46",Neutral,"0,15",Tolerated,"27,97","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_057,12,11905441,A,C,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr31Pro/c.91A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),4128,49,4200,"0,0116666667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,46",Neutral,"0,15",Tolerated,"27,86","14,86"
"low bq, low freq, many artifacts",UPN2_013,12,11905441,A,C,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr31Pro/c.91A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),1939,22,1967,"0,011184545",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,46",Neutral,"0,15",Tolerated,"28,83",15
"low freq, many artifacts",UPN2_006,12,11905450,C,T,missense_variant(MODERATE|MISSENSE|Cat/Tat|p.His34Tyr/c.100C>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),2636,37,2677,"0,0138214419",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,22",Neutral,"0,132",Tolerated,"34,37","35,19"
"low freq, many artifacts",UPN2_048,12,11905451,A,T,missense_variant(MODERATE|MISSENSE|cAt/cTt|p.His34Leu/c.101A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),3251,33,3297,"0,0100090992",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,275,Tolerated,"34,42","31,76"
"low freq, many artifacts",UPN2_041,12,11905454,T,C,missense_variant(MODERATE|MISSENSE|gTt/gCt|p.Val35Ala/c.104T>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),2893,44,2956,"0,0148849797",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,39",Neutral,1,Tolerated,"33,75","33,57"
"low bq, low freq, many artifacts",UPN2_058,12,11905460,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val37Glu/c.110T>A|452|ETV6|protein_coding|CODING|ENST00000396373|2|A),3442,38,3488,"0,0108944954",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,41",Neutral,104,Tolerated,"34,49","19,71"
"low freq, many artifacts",UPN2_044,12,11905462,C,T,missense_variant(MODERATE|MISSENSE|Cct/Tct|p.Pro38Ser/c.112C>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),1550,54,1607,"0,0336029869",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,1",Neutral,"0,429",Tolerated,"33,99","34,91"
"low freq, many artifacts",UPN2_044,12,11905465,C,T,stop_gained(HIGH|NONSENSE|Cga/Tga|p.Arg39*/c.115C>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),1570,37,1607,"0,0230242688",0,0,0,0,1,0,0,1,2,NO,NO,COSM88481,ovary,1,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,66","32,95"
"low freq, many artifacts",UPN2_041,12,11905466,G,T,missense_variant(MODERATE|MISSENSE|cGa/cTa|p.Arg39Leu/c.116G>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),2912,35,2955,"0,0118443316",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,55",Neutral,"0,1",Tolerated,"33,83","30,51"
"low bq, low freq, many artifacts, many samples",UPN2_006,12,11905476,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg42Ser/c.126G>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),5133,52,5191,"0,0100173377",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,05",Neutral,42,Damaging,"30,7",14
"low bq, low freq, many artifacts, many samples",UPN2_049,12,11905476,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg42Ser/c.126G>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),7017,80,7102,"0,0112644326",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,05",Neutral,42,Damaging,"30,15","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_051,12,11905476,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg42Ser/c.126G>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),10483,110,10601,"0,0103763796",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,05",Neutral,42,Damaging,"30,02","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_009,12,11905476,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg42Ser/c.126G>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),19655,199,19873,"0,0100135863",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,05",Neutral,42,Damaging,"30,76","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_010,12,11905476,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg42Ser/c.126G>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),10313,117,10438,"0,0112090439",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,05",Neutral,42,Damaging,"30,72","15,37"
"low bq, low freq, many artifacts, many samples",UPN2_012,12,11905476,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg42Ser/c.126G>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),6775,69,6850,"0,0100729927",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,05",Neutral,42,Damaging,"30,6","15,09"
"low bq, low freq, many artifacts",UPN2_013,12,11905476,G,T,missense_variant(MODERATE|MISSENSE|agG/agT|p.Arg42Ser/c.126G>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),3787,40,3827,"0,0104520512",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,05",Neutral,42,Damaging,"30,74","17,1"
"low bq, many samples",UPN2_001,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),5278,123,5424,"0,0226769912",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"29,45","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_014,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),7017,112,7154,"0,0156555773",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"30,19","16,01"
"low bq, low freq, many artifacts, many samples",UPN2_015,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),11275,167,11488,"0,0145369081",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"30,33","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_016,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),5329,55,5398,"0,0101889589",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"30,17","16,49"
"low bq, low freq, many artifacts, many samples",UPN2_017,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),4484,68,4564,"0,0148992112",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"30,34","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_018,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),7230,103,7362,"0,0139907634",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"30,21","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_019,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),5939,85,6038,"0,0140775091",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"30,26","15,55"
"low bq, low freq, many artifacts, many samples",UPN2_020,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),5307,75,5405,"0,0138760407",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"30,36","16,01"
"low bq, low freq, many artifacts, many samples",UPN2_021,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),5232,82,5323,"0,0154048469",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"30,21","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_002,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),6682,99,6797,"0,0145652494",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"29,54","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_003,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),1198,23,1226,"0,0187601958",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"29,63","15,91"
"low bq, low freq, many artifacts, many samples",UPN2_022,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),6923,99,7039,"0,0140644978",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"30,25","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_023,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),7779,113,7912,"0,0142821031",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"30,25","15,17"
"low bq, low freq, many artifacts, many samples",UPN2_041,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),5583,90,5704,"0,0157784011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"30,1","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_024,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),4539,64,4611,"0,0138798525",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"30,22","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_025,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),11325,166,11512,"0,0144197359",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"30,13","15,86"
"low bq, low freq, many artifacts, many samples",UPN2_026,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),9309,125,9482,"0,0131828728",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"30,21","15,69"
"low bq, low freq, many artifacts, many samples",UPN2_027,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),7947,108,8082,"0,013363029",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"30,37","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_042,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),18235,365,18667,"0,0195532223",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"30,05","15,98"
"low bq, low freq, many artifacts, many samples",UPN2_028,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),4858,75,4942,"0,0151760421",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"30,22","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_043,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),11669,218,11955,"0,0182350481",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"30,06","16,4"
"low bq, low freq, many artifacts, many samples",UPN2_044,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),3064,48,3119,"0,0153895479",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"30,06","16,02"
"low bq, low freq, many artifacts, many samples",UPN2_029,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),6054,80,6164,"0,0129785853",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"30,24","16,77"
"low bq, low freq, many artifacts, many samples",UPN2_030,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),9186,150,9392,"0,0159710392",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"30,3","15,89"
"low bq, low freq, many artifacts, many samples",UPN2_031,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),7206,125,7355,"0,0169952413",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"30,16","16,16"
"low bq, low freq, many artifacts, many samples",UPN2_005,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),1887,30,1928,"0,015560166",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"29,58","18,97"
"low bq, low freq, many artifacts, many samples",UPN2_045,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),16996,297,17373,"0,017095493",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"30,02","15,64"
"low bq, low freq, many artifacts, many samples",UPN2_032,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),2026,30,2066,"0,0145208132",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"30,17","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_046,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),11012,218,11276,"0,0193330968",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"30,03","15,48"
"low bq, low freq, many artifacts, many samples",UPN2_033,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),4881,84,4979,"0,0168708576",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"30,25","16,19"
"low bq, low freq, many artifacts, many samples",UPN2_034,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),1928,25,1966,"0,012716175",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"30,27","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_047,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),16154,328,16571,"0,0197936154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"30,07","15,63"
"low bq, low freq, many artifacts, many samples",UPN2_048,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),6236,123,6383,"0,0192699358",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"29,93","17,1"
"low bq, low freq, many artifacts, many samples",UPN2_035,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),9340,131,9525,"0,0137532808",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"30,28","15,86"
"low bq, low freq, many artifacts, many samples",UPN2_036,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),9584,149,9770,"0,0152507677",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"30,26","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_006,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),5100,102,5223,"0,0195290063",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"29,46","15,49"
"low bq, many samples",UPN2_049,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),6927,178,7138,"0,0249369571",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"30,18","16,85"
"low bq, low freq, many artifacts, many samples",UPN2_050,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),9193,176,9415,"0,0186935741",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"29,99","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_037,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),13469,167,13688,"0,0122004676",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"30,33","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_051,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),10363,217,10631,"0,0204120026",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"29,95","16,18"
"low bq, low freq, many artifacts, many samples",UPN2_052,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),8208,124,8364,"0,0148254424",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"30,02","15,81"
"low bq, low freq, many artifacts, many samples",UPN2_038,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),14113,186,14345,"0,0129661903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"30,19","15,66"
"low bq, low freq, many artifacts, many samples",UPN2_039,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),24089,342,24516,"0,0139500734",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"30,25","15,46"
"low bq, low freq, many artifacts, many samples",UPN2_053,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),14271,285,14644,"0,0194618957",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"29,99","15,42"
"low bq, low freq, many artifacts, many samples",UPN2_054,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),6675,112,6831,"0,0163958425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"29,97","15,82"
"low bq, low freq, many artifacts, many samples",UPN2_007,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),13327,222,13609,"0,0163127342",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"29,52","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_008,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),22598,284,22974,"0,0123618003",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"30,83","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_009,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),19532,334,19948,"0,0167435332",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"29,57","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_010,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),10215,217,10486,"0,020694259",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"29,67","15,62"
"low bq, low freq, many artifacts, many samples",UPN2_011,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),11472,202,11733,"0,0172163982",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"29,68","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_055,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),15442,282,15813,"0,0178334282",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"29,99","15,78"
"low bq, many samples",UPN2_056,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),4351,113,4480,"0,0252232143",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"29,88","18,25"
"low bq, low freq, many artifacts, many samples",UPN2_057,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),7927,141,8100,"0,0174074074",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"29,95","15,8"
"low bq, low freq, many artifacts, many samples",UPN2_058,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),6586,124,6745,"0,0183839881",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"30,09","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_012,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),6714,131,6877,"0,0190490039",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"29,61","15,59"
"low bq, low freq, many artifacts, many samples",UPN2_040,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),9695,159,9887,"0,0160817235",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"30,36","16,19"
"low bq, low freq, many artifacts, many samples",UPN2_013,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),3757,59,3843,"0,0153525891",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"29,63","15,61"
"low bq, low freq, many artifacts",UPN2_091,12,11905477,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met43Leu/c.127A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),2958,31,2996,"0,0103471295",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,297,Tolerated,"30,16","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_001,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),5304,107,5430,"0,0197053407",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"27,62","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_014,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),7019,110,7155,"0,0153738644",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"27,09","14,3"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_015,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),11256,188,11496,"0,0163535143",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"26,94","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_016,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),5280,98,5399,"0,0181515095",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"27,23","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_017,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),4454,87,4566,"0,0190538765",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"27,03","16,99"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_018,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),7194,141,7364,"0,0191472026",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"26,9","14,85"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_019,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),5907,110,6039,"0,0182149362",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"26,78",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_020,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),5275,106,5408,"0,0196005917",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"26,91","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_021,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),5218,85,5325,"0,0159624413",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"27,06","14,16"
"low bq, many samples",UPN2_002,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),6624,161,6806,"0,023655598",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"27,68","14,61"
"low bq, many samples",UPN2_003,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),1192,29,1226,"0,0236541599",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"27,77",14
"low bq, low freq, many artifacts, many samples",UPN2_022,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),6872,136,7041,"0,0193154381",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"27,11","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_023,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),7724,155,7918,"0,0195756504",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"27,1","15,3"
"low bq, low freq, many artifacts, many samples",UPN2_041,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),5577,102,5709,"0,0178665265",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,4","14,13"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_024,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),4491,90,4614,"0,0195058518",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"26,98","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_025,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),11258,209,11514,"0,0181518152",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"27,11","14,77"
"low freq, many artifacts, many samples",UPN2_026,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),9269,178,9484,"0,0187684521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,27,"14,35"
"low bq, low freq, many artifacts, many samples",UPN2_027,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),7899,139,8083,"0,0171965854",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"27,06","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_089,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),3986,58,4056,"0,0142998028",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,29","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_042,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),18258,355,18683,"0,0190012311",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,38","14,46"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_028,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),4817,104,4944,"0,0210355987",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"26,78","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_043,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),11681,211,11968,"0,0176303476",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,44","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_044,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),3054,51,3123,"0,0163304515",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,31","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_029,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),6031,108,6168,"0,0175097276",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"27,07","14,25"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_030,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),9177,173,9396,"0,0184120903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"26,99","14,12"
"low freq, many artifacts, many samples",UPN2_031,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),7213,123,7357,"0,0167187712",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,27,"14,2"
"low bq, many samples",UPN2_005,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),1872,47,1928,"0,0243775934",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"27,82","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_045,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),17013,331,17402,"0,0190208022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,33","14,47"
"low bq, many samples",UPN2_032,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),2004,52,2066,"0,0251694095",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"27,12",14
"low bq, low freq, many artifacts, many samples",UPN2_046,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),11017,210,11287,"0,0186054753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,21","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_033,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),4873,93,4979,"0,0186784495",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"27,18","14,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_034,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),1925,32,1966,"0,016276704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"26,98",14
"low bq, low freq, many artifacts, many samples",UPN2_047,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),16188,313,16589,"0,0188679245",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,49","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_048,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),6238,122,6387,"0,0191012995",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,37","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_035,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),9332,163,9529,"0,0171056774",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"27,08","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_036,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),9550,189,9774,"0,0193370166",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"27,08","14,21"
"low bq, many samples",UPN2_006,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),5091,118,5227,"0,0225750909",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"27,48","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_049,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),7001,130,7150,"0,0181818182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,56","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_050,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),9215,165,9431,"0,0174954936",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,43","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_037,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),13378,248,13693,"0,0181114438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"27,02","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_051,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),10401,193,10645,"0,0181305777",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,42","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_052,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),8193,145,8370,"0,0173237754",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,2","14,35"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_038,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),14004,283,14347,"0,0197253781",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"26,97","14,57"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_039,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),23928,488,24524,"0,0198988746",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"26,88","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_053,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),14328,286,14671,"0,0194942403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,22","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_054,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),6688,130,6839,"0,019008627",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,29","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_007,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),13284,279,13626,"0,0204755614",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"27,88","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_008,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),22539,369,22997,"0,0160455712",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,77","14,74"
"low bq, many samples",UPN2_009,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),19463,450,19979,"0,0225236498",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"27,73","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_010,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),10247,224,10498,"0,0213373976",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"27,55","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_011,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),11458,242,11747,"0,0206010045",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"27,83","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_055,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),15428,291,15828,"0,0183851403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,34","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_056,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),4375,89,4483,"0,0198527772",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,53","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_090,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),3691,81,3777,"0,0214455917",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,02","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_057,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),7917,165,8112,"0,0203402367",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,51","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_058,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),6614,110,6749,"0,0162987109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,51","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_012,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),6724,132,6887,"0,0191665457",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"27,72","14,5"
"low bq, many samples",UPN2_060,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),576,34,613,"0,0554649266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"27,15","14,79"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_040,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),9656,166,9888,"0,0167880259",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"26,98","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_013,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),3763,74,3846,"0,0192407696",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"27,7","14,19"
"low bq, low freq, many artifacts, many samples",UPN2_091,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),2952,46,2999,"0,0153384461",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,15","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_092,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),1443,25,1476,"0,0169376694",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,27","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_093,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),2137,28,2167,"0,0129210891",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,22","14,25"
"low bq, bad alignment, many samples",UPN2_061,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),1115,49,1170,"0,0418803419",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"26,98","14,14"
"low bq, bad alignment, many samples",UPN2_062,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),622,35,657,"0,0532724505",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"26,77","14,37"
"low bq, bad alignment, many samples",UPN2_064,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),367,22,392,"0,056122449",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"26,95","15,23"
"low bq, many samples",UPN2_071,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),1231,56,1293,"0,0433101315",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"27,14","14,84"
"low bq, many samples",UPN2_072,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),1072,48,1122,"0,0427807487",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"27,42","14,94"
"low bq, bad alignment, many samples",UPN2_075,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),696,39,736,"0,0529891304",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"26,98","14,97"
"low bq, many samples",UPN2_077,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),508,27,539,"0,0500927644",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"27,21","14,52"
"low bq, many samples",UPN2_078,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),565,38,606,"0,0627062706",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"27,02","14,53"
"low bq, bad alignment, many samples",UPN2_080,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),1119,56,1181,"0,0474174428",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"26,93","14,68"
"low bq, many samples",UPN2_081,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),1344,57,1409,"0,0404542229",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"27,2","14,68"
"low bq, many samples",UPN2_083,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),615,36,651,"0,0552995392",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"27,16","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_094,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),7782,127,7937,"0,0160010079",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,24","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_095,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),5157,96,5274,"0,0182025028",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,18","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_096,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),7909,135,8062,"0,0167452245",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,19","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_097,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),8806,153,8982,"0,0170340681",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,14","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_098,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),3644,56,3712,"0,0150862069",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,32","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_099,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),2571,49,2624,"0,0186737805",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,28","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_100,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),5241,86,5333,"0,0161260079",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,38","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_101,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),3654,77,3743,"0,0205717339",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,38","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_102,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),3876,68,3966,"0,0171457388",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,16","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_103,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),5882,112,6005,"0,0186511241",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,21","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_104,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),7862,119,8007,"0,0148619958",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,15","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_105,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),6805,117,6949,"0,016836955",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,06","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_106,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),10765,204,10989,"0,0185640186",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,31","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_107,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),8155,166,8340,"0,0199040767",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,33","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_108,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),5645,102,5762,"0,0177021867",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,3","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_109,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),7831,139,8021,"0,01732951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,22","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_110,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),8575,186,8786,"0,0211700433",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,19","14,26"
"low bq, low freq, many artifacts",UPN2_111,12,11905478,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met43Arg/c.128T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),5520,108,5642,"0,0191421482",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,97,Tolerated,"28,28","14,06"
"low bq, low freq, many artifacts, many samples",UPN2_001,12,11905481,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu44Val/c.131A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),5322,82,5451,"0,0150431114",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,2,Damaging,"29,59","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_014,12,11905481,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu44Val/c.131A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),7030,92,7171,"0,012829452",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,2,Damaging,"30,05","15,63"
"low bq, low freq, many artifacts, many samples",UPN2_002,12,11905481,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu44Val/c.131A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),6705,81,6831,"0,0118577075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,2,Damaging,"29,61","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_041,12,11905481,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu44Val/c.131A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),5624,70,5731,"0,0122142733",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,2,Damaging,"30,33","16,16"
"low bq, low freq, many artifacts, many samples",UPN2_025,12,11905481,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu44Val/c.131A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),11342,122,11527,"0,0105838466",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,2,Damaging,"30,11","16,89"
"low bq, low freq, many artifacts, many samples",UPN2_027,12,11905481,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu44Val/c.131A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),7981,86,8098,"0,0106199061",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,2,Damaging,"30,1","17,13"
"low bq, low freq, many artifacts, many samples",UPN2_042,12,11905481,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu44Val/c.131A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),18351,252,18744,"0,0134443022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,2,Damaging,"30,41","15,9"
"low bq, low freq, many artifacts, many samples",UPN2_043,12,11905481,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu44Val/c.131A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),11765,158,12005,"0,0131611828",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,2,Damaging,"30,41","16,31"
"low bq, low freq, many artifacts, many samples",UPN2_030,12,11905481,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu44Val/c.131A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),9263,97,9410,"0,0103081828",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,2,Damaging,"30,11","15,41"
"low bq, low freq, many artifacts, many samples",UPN2_031,12,11905481,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu44Val/c.131A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),7251,78,7369,"0,0105848826",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,2,Damaging,"30,13",16
"low bq, low freq, many artifacts, many samples",UPN2_005,12,11905481,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu44Val/c.131A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),1891,26,1931,"0,0134645262",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,2,Damaging,"29,67","16,35"
"low bq, low freq, many artifacts, many samples",UPN2_045,12,11905481,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu44Val/c.131A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),17077,241,17454,"0,0138077232",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,2,Damaging,"30,4","16,76"
"low bq, low freq, many artifacts, many samples",UPN2_032,12,11905481,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu44Val/c.131A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),2031,24,2070,"0,0115942029",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,2,Damaging,"29,97","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_046,12,11905481,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu44Val/c.131A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),11066,161,11336,"0,0142025406",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,2,Damaging,"30,35","16,1"
"low bq, low freq, many artifacts, many samples",UPN2_033,12,11905481,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu44Val/c.131A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),4902,51,4982,"0,0102368527",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,2,Damaging,"30,13","15,49"
"low bq, low freq, many artifacts, many samples",UPN2_047,12,11905481,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu44Val/c.131A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),16297,207,16630,"0,0124473842",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,2,Damaging,"30,42","16,38"
"low bq, low freq, many artifacts, many samples",UPN2_048,12,11905481,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu44Val/c.131A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),6288,74,6410,"0,0115444618",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,2,Damaging,"30,43","15,76"
"low bq, low freq, many artifacts, many samples",UPN2_006,12,11905481,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu44Val/c.131A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),5126,72,5237,"0,0137483292",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,2,Damaging,"29,82","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_049,12,11905481,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu44Val/c.131A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),7018,98,7161,"0,0136852395",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,2,Damaging,"30,32","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_050,12,11905481,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu44Val/c.131A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),9284,121,9460,"0,0127906977",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,2,Damaging,"30,46","15,83"
"low bq, low freq, many artifacts, many samples",UPN2_051,12,11905481,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu44Val/c.131A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),10475,139,10676,"0,0130198576",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,2,Damaging,"30,3","16,04"
"low bq, low freq, many artifacts, many samples",UPN2_052,12,11905481,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu44Val/c.131A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),8246,90,8386,"0,0107321727",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,2,Damaging,"30,47","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_038,12,11905481,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu44Val/c.131A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),14126,144,14362,"0,0100264587",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,2,Damaging,"30,2","15,62"
"low bq, low freq, many artifacts, many samples",UPN2_053,12,11905481,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu44Val/c.131A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),14398,225,14734,"0,0152708022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,2,Damaging,"30,35","16,4"
"low bq, low freq, many artifacts, many samples",UPN2_054,12,11905481,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu44Val/c.131A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),6724,81,6860,"0,0118075802",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,2,Damaging,"30,33","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_007,12,11905481,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu44Val/c.131A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),13368,187,13668,"0,013681592",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,2,Damaging,"29,96","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_009,12,11905481,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu44Val/c.131A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),19624,280,20041,"0,0139713587",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,2,Damaging,"29,81","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_010,12,11905481,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu44Val/c.131A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),10308,126,10516,"0,0119817421",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,2,Damaging,"29,81","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_011,12,11905481,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu44Val/c.131A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),11533,140,11761,"0,0119037497",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,2,Damaging,"29,93","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_055,12,11905481,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu44Val/c.131A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),15584,185,15881,"0,0116491405",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,2,Damaging,"30,35","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_056,12,11905481,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu44Val/c.131A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),4393,62,4504,"0,0137655417",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,2,Damaging,"30,35","15,73"
"low bq, low freq, many artifacts, many samples",UPN2_057,12,11905481,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu44Val/c.131A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),7935,124,8134,"0,0152446521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,2,Damaging,"30,36","15,93"
"low bq, low freq, many artifacts, many samples",UPN2_058,12,11905481,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu44Val/c.131A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),6642,94,6770,"0,0138847858",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,2,Damaging,"30,38","15,85"
"low bq, low freq, many artifacts, many samples",UPN2_012,12,11905481,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu44Val/c.131A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),6758,97,6904,"0,0140498262",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,2,Damaging,"29,83","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_040,12,11905481,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu44Val/c.131A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),9749,106,9906,"0,0107005855",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,2,Damaging,"30,24","16,38"
"low bq, low freq, many artifacts",UPN2_013,12,11905481,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu44Val/c.131A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),3764,49,3855,"0,0127107652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,2,Damaging,"29,96",14
"low bq, low freq, many artifacts, many samples",UPN2_058,12,11905485,A,C,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu45Asp/c.135A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),6585,69,6795,"0,0101545254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,61","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_061,12,11905485,A,C,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu45Asp/c.135A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),1134,21,1178,"0,0178268251",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,16",14
"low bq, low freq, many artifacts, many samples",UPN2_080,12,11905485,A,C,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu45Asp/c.135A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),1141,23,1185,"0,0194092827",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"27,86",14
"low bq, low freq, many artifacts",UPN2_081,12,11905485,A,C,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu45Asp/c.135A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),1369,22,1419,"0,015503876",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,17","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_001,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),5307,91,5464,"0,0166544656",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,25","15,41"
"low bq, low freq, many artifacts, many samples",UPN2_014,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),7014,117,7178,"0,016299805",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,36","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_015,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),11233,174,11518,"0,0151067894",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,13","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_016,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),5268,97,5411,"0,0179264461",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,68","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_017,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),4457,83,4579,"0,0181262284",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,2","15,52"
"low bq, low freq, many artifacts, many samples",UPN2_018,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),7180,129,7385,"0,0174678402",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,21","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_019,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),5937,65,6056,"0,0107331572",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,21","15,77"
"low bq, low freq, many artifacts, many samples",UPN2_020,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),5282,87,5414,"0,0160694496",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,36","15,95"
"low bq, low freq, many artifacts, many samples",UPN2_021,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),5219,69,5342,"0,0129165107",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,41","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_002,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),6649,108,6850,"0,0157664234",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,21","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_003,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),1200,22,1231,"0,0178716491",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"27,94","15,41"
"low bq, low freq, many artifacts, many samples",UPN2_022,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),6900,99,7057,"0,0140286241",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,33","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_023,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),7744,134,7939,"0,0168787001",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,13","15,23"
"low bq, many samples",UPN2_041,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),5547,134,5745,"0,0233246301",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,48","15,45"
"low bq, low freq, many artifacts, many samples",UPN2_024,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),4501,82,4624,"0,017733564",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,21","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_025,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),11260,170,11541,"0,0147300927",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,27","15,41"
"low bq, low freq, many artifacts, many samples",UPN2_026,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),9267,133,9505,"0,0139926355",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"27,99","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_027,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),7901,125,8111,"0,01541117",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,09","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_042,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),18133,400,18799,"0,0212777275",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,43","15,59"
"low bq, low freq, many artifacts, many samples",UPN2_028,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),4827,78,4954,"0,0157448526",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"27,97","16,04"
"low bq, low freq, many artifacts, many samples",UPN2_043,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),11629,261,12039,"0,0216795415",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,77","15,7"
"low bq, low freq, many artifacts, many samples",UPN2_044,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),3041,65,3138,"0,0207138305",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,63","16,62"
"low bq, low freq, many artifacts, many samples",UPN2_029,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),6041,103,6185,"0,0166531932",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,07","15,63"
"low bq, low freq, many artifacts, many samples",UPN2_030,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),9204,116,9418,"0,0123168401",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,14","15,17"
"low bq, low freq, many artifacts, many samples",UPN2_031,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),7204,108,7378,"0,0146381133",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,11","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_005,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),1886,30,1937,"0,0154878678",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,19","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_045,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),16965,351,17506,"0,0200502685",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,4","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_032,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),2005,38,2071,"0,0183486239",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,09","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_046,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),10999,230,11369,"0,0202304512",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,55","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_033,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),4830,97,4986,"0,0194544725",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,24","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_034,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),1927,30,1973,"0,0152052712",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,48","16,67"
"low bq, low freq, many artifacts, many samples",UPN2_047,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),16138,340,16677,"0,0203873598",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,55","15,62"
"low bq, many samples",UPN2_048,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),6215,144,6423,"0,0224194302",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,51","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_035,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),9299,164,9558,"0,0171584013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,27","15,98"
"low bq, low freq, many artifacts, many samples",UPN2_036,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),9548,153,9809,"0,0155979203",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,16","15,48"
"low bq, low freq, many artifacts, many samples",UPN2_006,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),5108,82,5247,"0,0156279779",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,2","14,6"
"low bq, many samples",UPN2_049,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),6924,173,7182,"0,0240879978",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,49","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_050,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),9170,203,9489,"0,0213931921",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,38","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_037,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),13421,178,13724,"0,0129699796",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,17","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_051,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),10339,231,10712,"0,0215646004",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,63","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_052,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),8157,153,8403,"0,0182077829",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,48","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_038,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),14017,226,14376,"0,0157206455",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,04","15,82"
"low bq, low freq, many artifacts, many samples",UPN2_039,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),23984,370,24601,"0,015040039",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"27,97","15,56"
"low bq, low freq, many artifacts, many samples",UPN2_053,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),14288,288,14774,"0,0194937052",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,22","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_054,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),6691,118,6880,"0,0171511628",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,27","15,98"
"low bq, low freq, many artifacts, many samples",UPN2_007,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),13308,237,13700,"0,0172992701",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,46","15,31"
"low bq, low freq, many artifacts, many samples",UPN2_008,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),22545,331,23070,"0,0143476376",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"29,79","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_009,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),19546,316,20080,"0,0157370518",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,32","15,63"
"low bq, low freq, many artifacts, many samples",UPN2_010,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),10261,186,10555,"0,0176219801",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,28","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_011,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),11448,210,11787,"0,0178162382",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,44",15
"low bq, low freq, many artifacts, many samples",UPN2_055,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),15449,296,15926,"0,0185859601",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,35","15,76"
"low bq, low freq, many artifacts, many samples",UPN2_056,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),4365,80,4521,"0,0176952002",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,32","15,75"
"low bq, many samples",UPN2_057,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),7881,184,8153,"0,0225683797",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,53","16,03"
"low bq, low freq, many artifacts, many samples",UPN2_012,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),6692,121,6919,"0,0174880763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,3","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_040,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),9638,163,9918,"0,0164347651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,22","15,63"
"low bq, low freq, many artifacts, many samples",UPN2_013,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),3750,73,3860,"0,0189119171",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,37","15,44"
low bq,UPN2_083,12,11905485,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu45Asp/c.135A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),624,20,655,"0,0305343511",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,454,Tolerated,"28,8","25,7"
"low bq, low freq, many artifacts, many samples",UPN2_001,12,11905487,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp46Ala/c.137A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),5385,55,5482,"0,0100328347",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,196,Tolerated,"29,66","16,2"
"low bq, low freq, many artifacts, many samples",UPN2_041,12,11905487,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp46Ala/c.137A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),5635,74,5768,"0,0128294036",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,196,Tolerated,"28,68",15
"low bq, low freq, many artifacts, many samples",UPN2_042,12,11905487,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp46Ala/c.137A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),18503,200,18855,"0,010607266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,196,Tolerated,"28,66","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_043,12,11905487,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp46Ala/c.137A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),11821,151,12080,"0,0125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,196,Tolerated,"28,65","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_045,12,11905487,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp46Ala/c.137A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),17128,221,17557,"0,0125875719",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,196,Tolerated,"28,57","15,95"
"low bq, low freq, many artifacts, many samples",UPN2_046,12,11905487,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp46Ala/c.137A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),11192,122,11397,"0,0107045714",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,196,Tolerated,"28,44","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_034,12,11905487,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp46Ala/c.137A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),1943,20,1976,"0,0101214575",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,196,Tolerated,"29,27",14
"low bq, low freq, many artifacts, many samples",UPN2_047,12,11905487,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp46Ala/c.137A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),16384,205,16724,"0,0122578331",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,196,Tolerated,"28,67","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_048,12,11905487,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp46Ala/c.137A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),6309,70,6428,"0,0108898569",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,196,Tolerated,"28,44","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_049,12,11905487,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp46Ala/c.137A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),7029,95,7204,"0,0131871183",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,196,Tolerated,"28,76","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_050,12,11905487,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp46Ala/c.137A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),9318,107,9515,"0,011245402",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,196,Tolerated,"28,7","14,19"
"low bq, low freq, many artifacts, many samples",UPN2_051,12,11905487,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp46Ala/c.137A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),10524,120,10736,"0,0111773472",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,196,Tolerated,"28,72","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_052,12,11905487,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp46Ala/c.137A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),8236,103,8425,"0,0122255193",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,196,Tolerated,"28,54","14,19"
"low bq, low freq, many artifacts, many samples",UPN2_053,12,11905487,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp46Ala/c.137A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),14493,183,14820,"0,0123481781",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,196,Tolerated,"28,49","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_054,12,11905487,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp46Ala/c.137A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),6734,95,6897,"0,0137741047",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,196,Tolerated,"28,58","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_011,12,11905487,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp46Ala/c.137A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),11634,119,11852,"0,0100404995",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,196,Tolerated,"29,7","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_055,12,11905487,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp46Ala/c.137A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),15675,178,15979,"0,0111396208",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,196,Tolerated,"28,61","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_056,12,11905487,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp46Ala/c.137A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),4412,62,4536,"0,0136684303",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,196,Tolerated,"28,6","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_090,12,11905487,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp46Ala/c.137A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),3694,38,3783,"0,0100449379",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,196,Tolerated,"29,15",14
"low bq, low freq, many artifacts, many samples",UPN2_057,12,11905487,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp46Ala/c.137A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),7990,92,8168,"0,0112634672",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,196,Tolerated,"28,52","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_012,12,11905487,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp46Ala/c.137A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),6801,72,6937,"0,0103791264",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,196,Tolerated,"29,74","15,35"
"low bq, bad alignment, many samples",UPN2_061,12,11905487,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp46Ala/c.137A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),1129,41,1180,"0,0347457627",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,196,Tolerated,"26,36","15,2"
"low bq, bad alignment, many samples",UPN2_071,12,11905487,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp46Ala/c.137A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),1244,49,1301,"0,0376633359",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,196,Tolerated,"26,35","14,82"
"low bq, bad alignment, many samples",UPN2_072,12,11905487,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp46Ala/c.137A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),1088,36,1128,"0,0319148936",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,196,Tolerated,"26,32","15,08"
"low bq, bad alignment, many samples",UPN2_075,12,11905487,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp46Ala/c.137A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),715,24,745,"0,0322147651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,196,Tolerated,"26,18","15,29"
"low bq, bad alignment, many samples",UPN2_076,12,11905487,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp46Ala/c.137A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),523,20,547,"0,0365630713",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,196,Tolerated,"26,15",14
"low bq, bad alignment, many samples",UPN2_078,12,11905487,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp46Ala/c.137A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),586,21,613,"0,0342577488",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,196,Tolerated,"26,21","14,33"
"low bq, bad alignment, many samples",UPN2_080,12,11905487,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp46Ala/c.137A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),1129,46,1186,"0,0387858347",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,196,Tolerated,"26,04","14,43"
"low bq, bad alignment, many samples",UPN2_081,12,11905487,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp46Ala/c.137A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),1365,43,1423,"0,0302178496",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,196,Tolerated,"26,47","14,47"
"low bq, bad alignment, many samples",UPN2_083,12,11905487,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp46Ala/c.137A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),631,21,656,"0,0320121951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,196,Tolerated,"26,08","15,24"
"low bq, bad alignment, many samples",UPN2_085,12,11905487,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp46Ala/c.137A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),322,21,344,"0,0610465116",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,196,Tolerated,"25,71","16,52"
"low bq, low freq, many artifacts, many samples",UPN2_094,12,11905487,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp46Ala/c.137A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),7850,84,7965,"0,0105461394",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,196,Tolerated,"29,15","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_101,12,11905487,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp46Ala/c.137A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),3697,40,3757,"0,0106467927",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,196,Tolerated,"29,16","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_102,12,11905487,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp46Ala/c.137A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),3910,47,3980,"0,0118090452",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,196,Tolerated,"28,72",15
"low bq, low freq, many artifacts, many samples",UPN2_104,12,11905487,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp46Ala/c.137A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),7890,87,8033,"0,0108303249",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,196,Tolerated,"28,99","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_106,12,11905487,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp46Ala/c.137A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),10858,111,11028,"0,0100652884",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,196,Tolerated,"28,94","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_108,12,11905487,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp46Ala/c.137A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),5702,60,5782,"0,0103770322",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,196,Tolerated,"29,04","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_109,12,11905487,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp46Ala/c.137A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),7920,96,8045,"0,0119328776",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,196,Tolerated,"28,96","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_110,12,11905487,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp46Ala/c.137A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),8647,120,8816,"0,0136116152",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,196,Tolerated,"28,91","14,87"
"low bq, low freq, many artifacts",UPN2_111,12,11905487,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp46Ala/c.137A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),5577,58,5663,"0,0102419212",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,196,Tolerated,"28,9","15,6"
"low bq, low freq, many artifacts, many samples",UPN2_071,12,11905488,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp46Glu/c.138C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),1279,21,1301,"0,0161414297",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,07",Neutral,1,Tolerated,"29,13","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_098,12,11905488,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp46Glu/c.138C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),3681,40,3726,"0,0107353731",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,07",Neutral,1,Tolerated,"29,41",14
"low bq, low freq, many artifacts, many samples",UPN2_099,12,11905488,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp46Glu/c.138C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),2606,27,2635,"0,0102466793",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,07",Neutral,1,Tolerated,"29,41",14
"inspected, many artifacts",UPN2_061,12,11905489,T,C,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser47Pro/c.139T>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),1130,26,1180,"0,0220338983",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,27",Neutral,"0,335",Tolerated,"29,15","29,12"
"low bq, many samples",UPN2_071,12,11905489,T,G,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser47Ala/c.139T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),1267,32,1302,"0,024577573",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,01",Neutral,852,Tolerated,"29,2","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_072,12,11905489,T,G,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser47Ala/c.139T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),1100,23,1129,"0,0203720106",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,01",Neutral,852,Tolerated,"28,64","14,57"
"low bq, many samples",UPN2_080,12,11905489,T,G,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser47Ala/c.139T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),1149,35,1186,"0,0295109612",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,01",Neutral,852,Tolerated,"28,63",14
"low bq, low freq, many artifacts",UPN2_081,12,11905489,T,G,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser47Ala/c.139T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),1385,27,1424,"0,0189606742",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,01",Neutral,852,Tolerated,"28,67","14,26"
"low freq, many artifacts",UPN2_090,12,11905490,C,T,missense_variant(MODERATE|MISSENSE|tCg/tTg|p.Ser47Leu/c.140C>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),3724,46,3786,"0,0121500264",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"0,39",Neutral,"0,372",Tolerated,"29,77","31,2"
"low bq, low freq, many artifacts, many samples",UPN2_072,12,11905492,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile48Leu/c.142A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),1089,23,1131,"0,0203359859",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,2",Neutral,644,Tolerated,"27,66","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_080,12,11905492,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile48Leu/c.142A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),1146,23,1186,"0,0193929174",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,2",Neutral,644,Tolerated,"27,16","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_081,12,11905492,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile48Leu/c.142A>C|452|ETV6|protein_coding|CODING|ENST00000396373|2|C),1377,29,1425,"0,0203508772",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,2",Neutral,644,Tolerated,"28,06","16,03"
"low bq, low freq, many artifacts, many samples",UPN2_017,12,11905492,A,T,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile48Phe/c.142A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),4524,46,4591,"0,0100196036",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,01",Neutral,535,Tolerated,"29,52","16,65"
"low bq, low freq, many artifacts, many samples",UPN2_041,12,11905492,A,T,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile48Phe/c.142A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),5670,69,5780,"0,0119377163",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,01",Neutral,535,Tolerated,"29,04","16,12"
"low bq, low freq, many artifacts, many samples",UPN2_043,12,11905492,A,T,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile48Phe/c.142A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),11872,123,12107,"0,0101594119",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,01",Neutral,535,Tolerated,"29,13","16,05"
"low bq, low freq, many artifacts, many samples",UPN2_048,12,11905492,A,T,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile48Phe/c.142A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),6331,70,6453,"0,0108476678",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,01",Neutral,535,Tolerated,"28,93","15,56"
"low bq, low freq, many artifacts, many samples",UPN2_049,12,11905492,A,T,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile48Phe/c.142A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),7066,91,7223,"0,0125986432",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,01",Neutral,535,Tolerated,"28,95","20,13"
"low bq, low freq, many artifacts, many samples",UPN2_050,12,11905492,A,T,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile48Phe/c.142A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),9363,96,9544,"0,0100586756",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,01",Neutral,535,Tolerated,"29,01","15,91"
"low bq, low freq, many artifacts, many samples",UPN2_051,12,11905492,A,T,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile48Phe/c.142A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),10562,122,10776,"0,0113214551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,01",Neutral,535,Tolerated,"29,09","15,58"
"low bq, low freq, many artifacts, many samples",UPN2_054,12,11905492,A,T,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile48Phe/c.142A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),6720,80,6918,"0,0115640358",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,01",Neutral,535,Tolerated,"28,88","15,88"
"low bq, low freq, many artifacts, many samples",UPN2_055,12,11905492,A,T,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile48Phe/c.142A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),15744,164,16023,"0,0102352868",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,01",Neutral,535,Tolerated,"29,03","16,02"
"low bq, low freq, many artifacts, many samples",UPN2_056,12,11905492,A,T,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile48Phe/c.142A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),4468,52,4554,"0,0114185332",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,01",Neutral,535,Tolerated,"29,02","15,6"
"low bq, low freq, many artifacts, many samples",UPN2_057,12,11905492,A,T,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile48Phe/c.142A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),8036,92,8199,"0,0112208806",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,01",Neutral,535,Tolerated,"28,97","15,34"
"low bq, low freq, many artifacts, many samples",UPN2_058,12,11905492,A,T,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile48Phe/c.142A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),6705,82,6829,"0,0120076146",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,01",Neutral,535,Tolerated,"29,34","18,55"
"low bq, low freq, many artifacts, many samples",UPN2_012,12,11905492,A,T,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile48Phe/c.142A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),6828,81,6955,"0,0116462976",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,01",Neutral,535,Tolerated,"30,12","17,04"
"low bq, low freq, many artifacts",UPN2_013,12,11905492,A,T,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile48Phe/c.142A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),3816,43,3878,"0,0110881898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,01",Neutral,535,Tolerated,"30,07","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_061,12,11905493,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile48Ser/c.143T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),1144,25,1182,"0,0211505922",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,96",Neutral,453,Tolerated,"28,33","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_071,12,11905493,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile48Ser/c.143T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),1274,25,1305,"0,0191570881",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,96",Neutral,453,Tolerated,"28,66","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_072,12,11905493,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile48Ser/c.143T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),1106,22,1131,"0,0194518126",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,96",Neutral,453,Tolerated,"28,56","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_081,12,11905493,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile48Ser/c.143T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),1396,24,1425,"0,0168421053",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,96",Neutral,453,Tolerated,"28,7","16,79"
"low bq, low freq, many artifacts",UPN2_099,12,11905493,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile48Ser/c.143T>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),2605,27,2638,"0,0102350265",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,96",Neutral,453,Tolerated,"30,6","14,26"
"low freq, many artifacts",UPN2_006,12,11905495,C,T,missense_variant(MODERATE|MISSENSE|Cgc/Tgc|p.Arg49Cys/c.145C>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),5112,150,5290,"0,0283553875",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-1,81",Neutral,"0,002",Damaging,"29,6","31,57"
"inspected, low bq, bad alignment",UPN2_059,12,11905501,C,T,missense_variant(MODERATE|MISSENSE|Cct/Tct|p.Pro51Ser/c.151C>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),272,29,301,"0,096345515",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,54",Deleterious,"0,09",Tolerated,"28,31","27,72"
"low bq, bad alignment, low freq, many artifacts",UPN2_081,12,11905502,C,G,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro51Arg/c.152C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),1405,21,1429,"0,0146955913",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,42",Deleterious,1,Damaging,"26,21","14,62"
"low freq, many artifacts",UPN2_044,12,11905504,G,T,missense_variant(MODERATE|MISSENSE|Gcg/Tcg|p.Ala52Ser/c.154G>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),1519,33,1553,"0,0212491951",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,"0,041",Damaging,"33,36","29,09"
"low bq, low freq, many artifacts",UPN2_049,12,11905507,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His53Asn/c.157C>A|452|ETV6|protein_coding|CODING|ENST00000396373|2|A),3502,38,3559,"0,0106771565",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,78,Tolerated,"30,56","16,08"
"low bq, low freq, many artifacts, many samples",UPN2_001,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),2642,47,2711,"0,0173367761",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"32,04","15,79"
"low bq, low freq, many artifacts, many samples",UPN2_014,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),3498,51,3561,"0,0143218197",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"32,45","17,98"
"low bq, low freq, many artifacts, many samples",UPN2_015,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),5613,85,5724,"0,0148497554",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"32,65","16,59"
"low bq, low freq, many artifacts, many samples",UPN2_016,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),2643,33,2688,"0,0122767857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"32,71","16,67"
"low bq, low freq, many artifacts, many samples",UPN2_017,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),2238,27,2277,"0,0118577075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"32,9","16,96"
"low bq, low freq, many artifacts, many samples",UPN2_018,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),3632,40,3678,"0,0108754758",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"32,63","16,08"
"low bq, low freq, many artifacts, many samples",UPN2_019,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),2957,48,3020,"0,0158940397",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"32,7","15,92"
"low bq, low freq, many artifacts, many samples",UPN2_020,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),2646,36,2695,"0,0133580705",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"32,68","16,31"
"low bq, low freq, many artifacts, many samples",UPN2_021,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),2610,38,2656,"0,0143072289",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"32,71","15,92"
"low bq, low freq, many artifacts, many samples",UPN2_002,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),3344,62,3414,"0,0181605155",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"32,59","15,71"
"low bq, low freq, many artifacts, many samples",UPN2_022,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),3431,51,3496,"0,0145881007",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"32,8","17,31"
"low bq, low freq, many artifacts, many samples",UPN2_023,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),3870,60,3950,"0,0151898734",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"32,54","15,23"
"low bq, many samples",UPN2_041,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),2772,63,2846,"0,0221363317",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"31,92","15,83"
"low bq, low freq, many artifacts, many samples",UPN2_024,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),2249,34,2294,"0,0148212729",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"32,82","16,15"
"low bq, low freq, many artifacts, many samples",UPN2_025,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),5622,83,5728,"0,0144902235",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"32,94","15,49"
"low bq, low freq, many artifacts, many samples",UPN2_026,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),4638,60,4717,"0,0127199491",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"32,71","15,62"
"low bq, low freq, many artifacts, many samples",UPN2_027,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),3943,57,4019,"0,0141826325",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"32,57","16,3"
"low bq, many samples",UPN2_042,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),9063,205,9315,"0,0220075148",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"31,82","16,91"
"low bq, low freq, many artifacts, many samples",UPN2_028,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),2423,33,2460,"0,0134146341",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"32,71","15,55"
"low bq, low freq, many artifacts, many samples",UPN2_043,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),5833,100,5962,"0,016772895",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"31,81","16,5"
"low bq, low freq, many artifacts, many samples",UPN2_044,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),1511,32,1550,"0,0206451613",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"31,92","15,66"
"low bq, low freq, many artifacts, many samples",UPN2_029,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),3023,42,3080,"0,0136363636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"32,84","17,26"
"low bq, low freq, many artifacts, many samples",UPN2_030,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),4582,76,4680,"0,0162393162",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"32,74","17,2"
"low bq, low freq, many artifacts, many samples",UPN2_031,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),3595,57,3666,"0,0155482815",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"32,73","15,77"
"low bq, low freq, many artifacts, many samples",UPN2_045,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),8476,170,8690,"0,0195627158",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"31,89","16,35"
"low bq, low freq, many artifacts, many samples",UPN2_046,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),5512,110,5644,"0,0194897236",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"31,88","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_033,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),2430,38,2479,"0,0153287616",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"32,87","19,34"
"low bq, low freq, many artifacts, many samples",UPN2_047,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),8062,151,8280,"0,018236715",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"31,76","15,17"
"low bq, low freq, many artifacts, many samples",UPN2_048,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),3100,68,3180,"0,0213836478",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"31,85","16,72"
"low bq, low freq, many artifacts, many samples",UPN2_035,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),4668,67,4750,"0,0141052632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"32,76","15,39"
"low bq, low freq, many artifacts, many samples",UPN2_036,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),4788,63,4876,"0,0129204266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"32,7","16,51"
"low bq, low freq, many artifacts, many samples",UPN2_006,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),2574,42,2622,"0,0160183066",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"32,42","15,14"
"low bq, many samples",UPN2_049,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),3462,79,3560,"0,0221910112",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"31,66","16,85"
"low bq, low freq, many artifacts, many samples",UPN2_050,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),4585,91,4693,"0,0193905817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"31,91","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_037,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),6715,88,6830,"0,0128843338",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"32,69","15,92"
"low bq, low freq, many artifacts, many samples",UPN2_051,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),5147,108,5293,"0,0204043076",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"31,7","16,15"
"low bq, low freq, many artifacts, many samples",UPN2_052,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),4047,89,4169,"0,0213480451",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"31,87","16,11"
"low bq, low freq, many artifacts, many samples",UPN2_038,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),7017,108,7157,"0,0150901216",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"32,73","17,35"
"low bq, low freq, many artifacts, many samples",UPN2_039,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),12066,156,12284,"0,0126994464",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"32,51","16,37"
"low bq, low freq, many artifacts, many samples",UPN2_053,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),7171,132,7333,"0,0180008182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"31,65","15,53"
"low bq, many samples",UPN2_054,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),3321,80,3420,"0,0233918129",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"31,78","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_007,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),6662,119,6820,"0,0174486804",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"32,42","16,92"
"low bq, low freq, many artifacts, many samples",UPN2_008,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),11293,157,11485,"0,0136700044",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"33,06","15,64"
"low bq, low freq, many artifacts, many samples",UPN2_009,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),9824,135,9999,"0,0135013501",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"32,36","15,5"
"low bq, low freq, many artifacts, many samples",UPN2_010,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),5171,67,5261,"0,0127352214",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"32,47","15,39"
"low bq, low freq, many artifacts, many samples",UPN2_011,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),5769,85,5891,"0,0144287897",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"32,63","15,46"
"low bq, many samples",UPN2_055,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),7697,182,7915,"0,0229943146",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"31,74","15,75"
"low bq, many samples",UPN2_056,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),2164,56,2245,"0,0249443207",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"31,74","15,18"
"low bq, many samples",UPN2_057,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),3894,114,4038,"0,0282317979",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"31,76","15,69"
"low bq, low freq, many artifacts, many samples",UPN2_058,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),3293,67,3380,"0,0198224852",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"31,88","16,84"
"low bq, low freq, many artifacts, many samples",UPN2_012,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),3380,54,3454,"0,0156340475",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"32,47","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_040,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),4842,64,4931,"0,0129791117",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"32,71","17,16"
"low bq, low freq, many artifacts",UPN2_013,12,11905508,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His53Leu/c.158A>T|452|ETV6|protein_coding|CODING|ENST00000396373|2|T),1870,36,1921,"0,0187402395",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-4,Deleterious,71,Tolerated,"32,33","16,33"
"low bq, low freq, many artifacts, many samples",UPN2_041,12,11905509,C,G,missense_variant(MODERATE|MISSENSE|caC/caG|p.His53Gln/c.159C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),2808,33,2848,"0,0115870787",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,48",Neutral,199,Tolerated,"29,81",14
"low bq, low freq, many artifacts, many samples",UPN2_043,12,11905509,C,G,missense_variant(MODERATE|MISSENSE|caC/caG|p.His53Gln/c.159C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),5878,60,5961,"0,0100654253",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,48",Neutral,199,Tolerated,"29,8","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_045,12,11905509,C,G,missense_variant(MODERATE|MISSENSE|caC/caG|p.His53Gln/c.159C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),8567,100,8694,"0,0115021854",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,48",Neutral,199,Tolerated,"29,7","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_046,12,11905509,C,G,missense_variant(MODERATE|MISSENSE|caC/caG|p.His53Gln/c.159C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),5554,69,5645,"0,0122232064",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,48",Neutral,199,Tolerated,"29,94","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_047,12,11905509,C,G,missense_variant(MODERATE|MISSENSE|caC/caG|p.His53Gln/c.159C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),8175,83,8282,"0,0100217339",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,48",Neutral,199,Tolerated,"29,72","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_048,12,11905509,C,G,missense_variant(MODERATE|MISSENSE|caC/caG|p.His53Gln/c.159C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),3139,32,3183,"0,0100534087",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,48",Neutral,199,Tolerated,"29,22","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_049,12,11905509,C,G,missense_variant(MODERATE|MISSENSE|caC/caG|p.His53Gln/c.159C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),3517,36,3563,"0,0101038451",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,48",Neutral,199,Tolerated,"29,95","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_050,12,11905509,C,G,missense_variant(MODERATE|MISSENSE|caC/caG|p.His53Gln/c.159C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),4625,53,4694,"0,0112910098",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,48",Neutral,199,Tolerated,"30,01","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_051,12,11905509,C,G,missense_variant(MODERATE|MISSENSE|caC/caG|p.His53Gln/c.159C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),5220,53,5293,"0,010013225",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,48",Neutral,199,Tolerated,"29,8","14,13"
"low bq, low freq, many artifacts, many samples",UPN2_053,12,11905509,C,G,missense_variant(MODERATE|MISSENSE|caC/caG|p.His53Gln/c.159C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),7228,79,7338,"0,0107658763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,48",Neutral,199,Tolerated,"29,73","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_054,12,11905509,C,G,missense_variant(MODERATE|MISSENSE|caC/caG|p.His53Gln/c.159C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),3384,36,3424,"0,0105140187",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,48",Neutral,199,Tolerated,"29,88","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_055,12,11905509,C,G,missense_variant(MODERATE|MISSENSE|caC/caG|p.His53Gln/c.159C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),7815,80,7918,"0,0101035615",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,48",Neutral,199,Tolerated,"29,77","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_090,12,11905509,C,G,missense_variant(MODERATE|MISSENSE|caC/caG|p.His53Gln/c.159C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),1857,22,1881,"0,0116959064",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,48",Neutral,199,Tolerated,"29,59","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_057,12,11905509,C,G,missense_variant(MODERATE|MISSENSE|caC/caG|p.His53Gln/c.159C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),3982,45,4038,"0,0111441308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,48",Neutral,199,Tolerated,"29,82","14,69"
"low bq, low freq, many artifacts",UPN2_100,12,11905509,C,G,missense_variant(MODERATE|MISSENSE|caC/caG|p.His53Gln/c.159C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),2621,29,2656,"0,0109186747",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,48",Neutral,199,Tolerated,"29,51",14
"low bq, low freq, many artifacts, many samples",UPN2_001,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),2662,40,2712,"0,0147492625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"27,56","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_014,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),3504,52,3561,"0,0146026397",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"27,26",14
"low bq, low freq, many artifacts, many samples",UPN2_015,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),5619,88,5727,"0,0153658111",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"28,11",14
"low bq, low freq, many artifacts, many samples",UPN2_016,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),2642,42,2690,"0,0156133829",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"27,4",14
"low bq, low freq, many artifacts, many samples",UPN2_017,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),2233,34,2277,"0,014931928",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"27,8","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_018,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),3628,38,3679,"0,0103288937",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"27,45",14
"low bq, low freq, many artifacts, many samples",UPN2_019,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),2964,43,3020,"0,0142384106",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"28,02",14
"low bq, low freq, many artifacts, many samples",UPN2_020,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),2649,38,2695,"0,0141001855",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"27,36","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_021,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),2614,38,2658,"0,0142964635",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"27,33","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_002,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),3348,47,3414,"0,0137668424",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"28,22","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_022,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),3440,42,3497,"0,0120102945",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"27,52","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_023,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),3890,50,3951,"0,012655024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"27,61",14
"low bq, bad alignment, many samples",UPN2_041,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),2743,82,2848,"0,0287921348",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"26,9",14
"low bq, low freq, many artifacts, many samples",UPN2_025,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),5633,84,5729,"0,0146622447",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"27,36","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_026,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),4640,64,4718,"0,0135650699",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"28,08","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_027,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),3951,58,4019,"0,0144314506",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"27,8","14,22"
"low bq, bad alignment, many samples",UPN2_089,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),1966,46,2019,"0,0227835562",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"26,7","14,15"
"low bq, bad alignment, many samples",UPN2_042,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),9031,240,9322,"0,0257455482",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"26,98","14,18"
"low bq, low freq, many artifacts, many samples",UPN2_028,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),2419,36,2461,"0,0146281999",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"27,98","14,36"
"low bq, many samples",UPN2_043,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),5776,143,5963,"0,0239812175",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"27,05","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_044,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),1517,27,1551,"0,0174081238",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"27,06",14
"low bq, low freq, many artifacts, many samples",UPN2_029,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),3026,49,3082,"0,015898767",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"27,89",14
"low bq, low freq, many artifacts, many samples",UPN2_030,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),4592,79,4682,"0,0168731311",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"27,75",14
"low bq, low freq, many artifacts, many samples",UPN2_031,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),3604,45,3667,"0,0122716117",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"27,62","14,69"
"low bq, many samples",UPN2_045,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),8429,210,8698,"0,0241434813",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"27,1","14,41"
"low bq, many samples",UPN2_046,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),5474,143,5645,"0,0253321523",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"27,08","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_033,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),2433,39,2480,"0,0157258065",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"27,73","14,33"
"low bq, many samples",UPN2_047,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),8038,196,8288,"0,0236486486",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"27,02","14,44"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_048,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),3106,62,3183,"0,0194784794",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"26,73",14
"low bq, low freq, many artifacts, many samples",UPN2_035,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),4663,72,4750,"0,0151578947",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"27,89","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_036,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),4800,63,4876,"0,0129204266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"27,78","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_006,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),2580,30,2622,"0,0114416476",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"27,94","14,73"
"low bq, bad alignment, many samples",UPN2_049,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),3430,104,3563,"0,0291888858",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"26,85","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_050,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),4572,96,4695,"0,0204472843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"27,17","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_037,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),6731,78,6831,"0,0114185332",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"28,03","14,23"
"low bq, bad alignment, many samples",UPN2_051,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),5130,124,5295,"0,0234183192",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"26,82","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_052,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),4066,82,4171,"0,0196595541",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"27,18","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_038,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),7040,98,7157,"0,0136928881",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"28,06","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_039,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),12111,150,12286,"0,0122090184",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"27,89","14,26"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),7121,160,7338,"0,0218043064",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"26,94","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_054,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),3345,60,3424,"0,0175233645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"27,14","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_007,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),6715,79,6823,"0,0115784845",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"27,55",14
"low bq, low freq, many artifacts, many samples",UPN2_009,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),9847,109,10001,"0,0108989101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"27,84","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_010,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),5181,56,5261,"0,0106443642",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"28,02",14
"low bq, low freq, many artifacts, many samples",UPN2_011,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),5765,88,5880,"0,0149659864",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"28,21","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_055,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),7701,166,7919,"0,0209622427",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"27,08","14,37"
"low bq, many samples",UPN2_056,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),2172,54,2246,"0,0240427427",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"27,14","14,46"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_090,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),1837,38,1882,"0,0201912859",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"26,45",14
"low bq, low freq, many artifacts, many samples",UPN2_057,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),3914,86,4038,"0,0212976721",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"27,4","14,15"
"low freq, many artifacts, many samples",UPN2_058,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),3279,74,3383,"0,0218740763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,27,"14,27"
"low bq, low freq, many artifacts, many samples",UPN2_012,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),3401,44,3456,"0,0127314815",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"27,77",14
"low bq, low freq, many artifacts, many samples",UPN2_040,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),4850,66,4932,"0,0133819951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"27,73","14,33"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_091,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),1463,31,1496,"0,0207219251",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"26,17",14
"low bq, bad alignment, many samples",UPN2_093,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),1052,26,1080,"0,0240740741",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"26,01","14,27"
"low bq, bad alignment, many samples",UPN2_061,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),561,21,584,"0,0359589041",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"26,9","14,67"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_094,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),3860,86,3959,"0,0217226572",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"26,38","14,36"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_095,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),2590,39,2634,"0,0148063781",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"26,76","14,33"
"low bq, bad alignment, many samples",UPN2_096,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),3890,108,4015,"0,0268991283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"26,34","14,24"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_097,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),4385,91,4484,"0,02029438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"26,3","14,14"
"low bq, bad alignment, many samples",UPN2_098,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),1801,42,1846,"0,022751896",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"26,48","14,17"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_099,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),1278,28,1308,"0,0214067278",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"26,25",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_100,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),2590,56,2656,"0,0210843373",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"26,08",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_101,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),1817,35,1857,"0,0188476037",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"26,99","14,37"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_102,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),1928,43,1976,"0,0217611336",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"26,42","14,63"
"low bq, bad alignment, many samples",UPN2_103,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),2925,68,2998,"0,0226817879",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"26,44",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_104,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),3906,78,3994,"0,0195292939",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"26,38","14,42"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_105,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),3387,70,3462,"0,0202195263",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"26,07","14,19"
"low bq, bad alignment, many samples",UPN2_106,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),5344,130,5489,"0,0236837311",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"26,25","14,1"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_107,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),4056,90,4163,"0,0216190247",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"26,18","14,08"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_108,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),2818,55,2877,"0,0191171359",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"26,28","14,4"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_109,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),3910,75,3992,"0,0187875752",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"26,63","14,44"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_110,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),4292,86,4392,"0,0195810565",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"26,12","14,15"
"low bq, bad alignment, low freq, many artifacts",UPN2_111,12,11905510,C,G,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu54Val/c.160C>G|452|ETV6|protein_coding|CODING|ENST00000396373|2|G),2762,47,2814,"0,0167022033",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,51",Deleterious,5,Damaging,"26,59","14,28"
"low freq, many artifacts",UPN2_048,12,11992104,A,G,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp65Gly/c.194A>G|452|ETV6|protein_coding|CODING|ENST00000396373|3|G),4069,56,4133,"0,0135494798",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,"0,002",Damaging,"34,58","35,54"
"low freq, many artifacts",UPN2_044,12,11992121,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys71Glu/c.211A>G|452|ETV6|protein_coding|CODING|ENST00000396373|3|G),2579,35,2634,"0,0132877752",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,-2,Neutral,"0,029",Damaging,"35,23","34,89"
"low freq, many artifacts",UPN2_044,12,11992124,T,A,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp72Arg/c.214T>A|452|ETV6|protein_coding|CODING|ENST00000396373|3|A),2578,49,2634,"0,0186028853",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-11,68",Deleterious,0,Damaging,"34,93","34,41"
"low freq, many artifacts",UPN2_048,12,11992132,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu74Asp/c.222A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),4042,75,4133,"0,0181466247",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,"0,019",Damaging,"34,88","35,52"
"low freq, many artifacts",UPN2_048,12,11992134,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn75Ile/c.224A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),4074,46,4133,"0,0111299298",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,46,Damaging,"35,45","34,3"
"low freq, many artifacts",UPN2_044,12,11992141,T,A,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe77Leu/c.231T>A|452|ETV6|protein_coding|CODING|ENST00000396373|3|A),2592,34,2633,"0,012913027",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,09",Deleterious,"0,005",Damaging,"34,95","33,82"
"low freq, many artifacts",UPN2_044,12,11992152,C,T,missense_variant(MODERATE|MISSENSE|cCa/cTa|p.Pro81Leu/c.242C>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),2577,46,2633,"0,0174705659",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,85",Deleterious,"0,083",Tolerated,"33,16","34,8"
"low bq, low freq, many artifacts, many samples",UPN2_059,12,11992160,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser84Arg/c.250A>C|452|ETV6|protein_coding|CODING|ENST00000396373|3|C),24522,353,25033,"0,0141013862",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,515,Tolerated,"30,42","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_060,12,11992160,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser84Arg/c.250A>C|452|ETV6|protein_coding|CODING|ENST00000396373|3|C),30745,368,31320,"0,0117496807",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,515,Tolerated,"30,51","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_061,12,11992160,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser84Arg/c.250A>C|452|ETV6|protein_coding|CODING|ENST00000396373|3|C),27564,401,28169,"0,0142355071",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,515,Tolerated,"30,29","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_062,12,11992160,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser84Arg/c.250A>C|452|ETV6|protein_coding|CODING|ENST00000396373|3|C),25829,403,26453,"0,015234567",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,515,Tolerated,"30,22","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_063,12,11992160,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser84Arg/c.250A>C|452|ETV6|protein_coding|CODING|ENST00000396373|3|C),20557,229,20905,"0,0109543171",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,515,Tolerated,"30,41","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_064,12,11992160,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser84Arg/c.250A>C|452|ETV6|protein_coding|CODING|ENST00000396373|3|C),25126,320,25628,"0,0124863431",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,515,Tolerated,"30,41","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_065,12,11992160,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser84Arg/c.250A>C|452|ETV6|protein_coding|CODING|ENST00000396373|3|C),26073,316,26576,"0,0118904275",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,515,Tolerated,"30,49","15,31"
"low bq, low freq, many artifacts, many samples",UPN2_066,12,11992160,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser84Arg/c.250A>C|452|ETV6|protein_coding|CODING|ENST00000396373|3|C),35009,454,35739,"0,0127032094",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,515,Tolerated,"30,56","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_067,12,11992160,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser84Arg/c.250A>C|452|ETV6|protein_coding|CODING|ENST00000396373|3|C),40481,500,41266,"0,0121165124",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,515,Tolerated,"30,59","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_068,12,11992160,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser84Arg/c.250A>C|452|ETV6|protein_coding|CODING|ENST00000396373|3|C),30759,469,31484,"0,0148964553",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,515,Tolerated,"30,37","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_069,12,11992160,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser84Arg/c.250A>C|452|ETV6|protein_coding|CODING|ENST00000396373|3|C),31864,434,32541,"0,013337021",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,515,Tolerated,"30,44","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_070,12,11992160,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser84Arg/c.250A>C|452|ETV6|protein_coding|CODING|ENST00000396373|3|C),21402,265,21834,"0,012137034",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,515,Tolerated,"30,33","15,51"
"low bq, low freq, many artifacts, many samples",UPN2_071,12,11992160,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser84Arg/c.250A>C|452|ETV6|protein_coding|CODING|ENST00000396373|3|C),18924,230,19280,"0,0119294606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,515,Tolerated,"30,54","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_072,12,11992160,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser84Arg/c.250A>C|452|ETV6|protein_coding|CODING|ENST00000396373|3|C),24929,275,25415,"0,0108203817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,515,Tolerated,"30,5","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_073,12,11992160,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser84Arg/c.250A>C|452|ETV6|protein_coding|CODING|ENST00000396373|3|C),20136,233,20504,"0,0113636364",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,515,Tolerated,"30,59","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_074,12,11992160,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser84Arg/c.250A>C|452|ETV6|protein_coding|CODING|ENST00000396373|3|C),20518,273,20944,"0,0130347594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,515,Tolerated,"30,41","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_075,12,11992160,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser84Arg/c.250A>C|452|ETV6|protein_coding|CODING|ENST00000396373|3|C),30762,381,31362,"0,0121484599",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,515,Tolerated,"30,65","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_076,12,11992160,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser84Arg/c.250A>C|452|ETV6|protein_coding|CODING|ENST00000396373|3|C),30460,411,31100,"0,0132154341",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,515,Tolerated,"30,27","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_077,12,11992160,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser84Arg/c.250A>C|452|ETV6|protein_coding|CODING|ENST00000396373|3|C),38176,618,39144,"0,0157878602",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,515,Tolerated,"30,38","15,3"
"low bq, low freq, many artifacts, many samples",UPN2_078,12,11992160,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser84Arg/c.250A>C|452|ETV6|protein_coding|CODING|ENST00000396373|3|C),29465,386,30001,"0,0128662378",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,515,Tolerated,"30,31","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_079,12,11992160,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser84Arg/c.250A>C|452|ETV6|protein_coding|CODING|ENST00000396373|3|C),16773,239,17163,"0,0139253044",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,515,Tolerated,"30,43","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_080,12,11992160,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser84Arg/c.250A>C|452|ETV6|protein_coding|CODING|ENST00000396373|3|C),30237,402,30890,"0,0130139204",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,515,Tolerated,"30,48","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_081,12,11992160,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser84Arg/c.250A>C|452|ETV6|protein_coding|CODING|ENST00000396373|3|C),34294,392,34962,"0,0112121732",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,515,Tolerated,"30,5","15,17"
"low bq, low freq, many artifacts, many samples",UPN2_082,12,11992160,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser84Arg/c.250A>C|452|ETV6|protein_coding|CODING|ENST00000396373|3|C),39880,483,40725,"0,0118600368",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,515,Tolerated,"30,52","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_083,12,11992160,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser84Arg/c.250A>C|452|ETV6|protein_coding|CODING|ENST00000396373|3|C),33363,518,34085,"0,0151973009",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,515,Tolerated,"30,17","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_084,12,11992160,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser84Arg/c.250A>C|452|ETV6|protein_coding|CODING|ENST00000396373|3|C),42327,521,43123,"0,0120817197",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,515,Tolerated,"30,39","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_085,12,11992160,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser84Arg/c.250A>C|452|ETV6|protein_coding|CODING|ENST00000396373|3|C),25622,341,26128,"0,0130511329",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,515,Tolerated,"30,41","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_086,12,11992160,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser84Arg/c.250A>C|452|ETV6|protein_coding|CODING|ENST00000396373|3|C),18410,286,18876,"0,0151515152",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,515,Tolerated,"30,27","14,95"
"low bq, low freq, many artifacts",UPN2_088,12,11992160,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser84Arg/c.250A>C|452|ETV6|protein_coding|CODING|ENST00000396373|3|C),29818,347,30376,"0,0114234922",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,515,Tolerated,"30,53","15,55"
"low bq, low freq, many artifacts",UPN2_047,12,11992184,A,T,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys92*/c.274A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),25681,277,26090,"0,0106170947",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,65","25,19"
"low bq, low freq, many artifacts",UPN2_050,12,11992186,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys92Asn/c.276A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),17401,179,17728,"0,0100970217",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,54",Deleterious,3,Damaging,"31,72","24,81"
"low bq, low freq, many artifacts",UPN2_044,12,11992202,A,T,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr98Ser/c.292A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),2543,27,2580,"0,0104651163",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,42",Deleterious,54,Tolerated,"34,11","20,67"
"low bq, low freq, many artifacts, many samples",UPN2_042,12,11992205,A,T,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys99*/c.295A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),10260,127,10454,"0,0121484599",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,29","17,41"
"low bq, low freq, many artifacts, many samples",UPN2_043,12,11992205,A,T,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys99*/c.295A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),8296,102,8436,"0,0120910384",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,24","15,93"
"low bq, low freq, many artifacts, many samples",UPN2_044,12,11992205,A,T,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys99*/c.295A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),2521,42,2580,"0,0162790698",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,29","17,12"
"low bq, low freq, many artifacts, many samples",UPN2_045,12,11992205,A,T,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys99*/c.295A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),7640,96,7775,"0,0123472669",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,33","18,11"
"low bq, low freq, many artifacts, many samples",UPN2_046,12,11992205,A,T,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys99*/c.295A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),10380,132,10568,"0,0124905375",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,26","19,61"
"low bq, low freq, many artifacts, many samples",UPN2_047,12,11992205,A,T,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys99*/c.295A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),12736,140,12926,"0,0108308835",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,26","17,95"
"low bq, low freq, many artifacts, many samples",UPN2_049,12,11992205,A,T,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys99*/c.295A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),9681,124,9856,"0,0125811688",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,22","15,94"
"low bq, low freq, many artifacts, many samples",UPN2_050,12,11992205,A,T,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys99*/c.295A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),8691,89,8814,"0,010097572",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,3","17,82"
"low bq, low freq, many artifacts, many samples",UPN2_051,12,11992205,A,T,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys99*/c.295A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),9411,108,9568,"0,0112876254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,33","17,84"
"low bq, low freq, many artifacts, many samples",UPN2_053,12,11992205,A,T,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys99*/c.295A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),11124,139,11312,"0,0122878359",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,29","20,18"
"low bq, low freq, many artifacts, many samples",UPN2_054,12,11992205,A,T,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys99*/c.295A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),8808,91,8938,"0,0101812486",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,35","17,99"
"low bq, low freq, many artifacts, many samples",UPN2_055,12,11992205,A,T,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys99*/c.295A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),11081,127,11270,"0,0112688554",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,36","19,24"
"low bq, low freq, many artifacts, many samples",UPN2_056,12,11992205,A,T,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys99*/c.295A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),3571,45,3626,"0,0124103696",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,3","17,78"
"low bq, low freq, many artifacts, many samples",UPN2_057,12,11992205,A,T,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys99*/c.295A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),11847,161,12074,"0,0133344376",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,26","20,52"
"low bq, low freq, many artifacts",UPN2_058,12,11992205,A,T,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys99*/c.295A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),11901,163,12110,"0,0134599505",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,22","18,94"
"low bq, low freq, many artifacts, many samples",UPN2_042,12,11992206,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys99Ile/c.296A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),10277,124,10453,"0,0118626232",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,84",Deleterious,0,Damaging,"32,15","16,69"
"low bq, low freq, many artifacts, many samples",UPN2_043,12,11992206,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys99Ile/c.296A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),8286,116,8438,"0,0137473335",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,84",Deleterious,0,Damaging,"32,19","19,89"
"low bq, low freq, many artifacts, many samples",UPN2_044,12,11992206,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys99Ile/c.296A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),2535,35,2580,"0,0135658915",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,84",Deleterious,0,Damaging,"32,32","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_045,12,11992206,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys99Ile/c.296A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),7647,100,7776,"0,0128600823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,84",Deleterious,0,Damaging,"32,35","17,17"
"low bq, low freq, many artifacts, many samples",UPN2_046,12,11992206,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys99Ile/c.296A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),10361,143,10567,"0,0135326961",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,84",Deleterious,0,Damaging,"32,16","16,64"
"low bq, low freq, many artifacts, many samples",UPN2_047,12,11992206,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys99Ile/c.296A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),12671,194,12926,"0,01500851",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,84",Deleterious,0,Damaging,"32,28","17,09"
"low bq, low freq, many artifacts, many samples",UPN2_048,12,11992206,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys99Ile/c.296A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),3980,43,4047,"0,0106251544",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,84",Deleterious,0,Damaging,"32,29","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_049,12,11992206,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys99Ile/c.296A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),9684,134,9855,"0,0135971588",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,84",Deleterious,0,Damaging,"32,11","18,06"
"low bq, low freq, many artifacts, many samples",UPN2_050,12,11992206,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys99Ile/c.296A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),8650,109,8813,"0,0123680926",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,84",Deleterious,0,Damaging,"32,05","18,69"
"low bq, low freq, many artifacts, many samples",UPN2_051,12,11992206,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys99Ile/c.296A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),9425,100,9567,"0,0104525975",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,84",Deleterious,0,Damaging,"32,34","17,38"
"low bq, low freq, many artifacts, many samples",UPN2_052,12,11992206,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys99Ile/c.296A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),6983,93,7105,"0,0130893737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,84",Deleterious,0,Damaging,"32,11","18,39"
"low bq, low freq, many artifacts, many samples",UPN2_053,12,11992206,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys99Ile/c.296A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),11143,118,11313,"0,0104304782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,84",Deleterious,0,Damaging,"32,11","17,96"
"low bq, low freq, many artifacts, many samples",UPN2_054,12,11992206,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys99Ile/c.296A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),8797,92,8938,"0,0102931305",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,84",Deleterious,0,Damaging,"32,14","15,97"
"low bq, low freq, many artifacts, many samples",UPN2_055,12,11992206,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys99Ile/c.296A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),11087,118,11269,"0,0104712042",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,84",Deleterious,0,Damaging,"32,22","17,78"
"low bq, low freq, many artifacts, many samples",UPN2_056,12,11992206,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys99Ile/c.296A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),3563,45,3627,"0,0124069479",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,84",Deleterious,0,Damaging,"32,15","15,78"
"low bq, low freq, many artifacts, many samples",UPN2_057,12,11992206,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys99Ile/c.296A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),11855,148,12072,"0,0122597747",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,84",Deleterious,0,Damaging,"32,21","16,9"
"low bq, low freq, many artifacts, many samples",UPN2_058,12,11992206,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys99Ile/c.296A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),11909,148,12111,"0,0122202956",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,84",Deleterious,0,Damaging,"32,28","16,69"
"low bq, low freq, many artifacts",UPN2_071,12,11992206,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys99Ile/c.296A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),9542,98,9685,"0,0101187403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,84",Deleterious,0,Damaging,"31,9","17,23"
"low bq, low freq, many artifacts, many samples",UPN2_042,12,11992207,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys99Asn/c.297A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),10244,124,10454,"0,0118614884",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,0,Damaging,"32,06","20,34"
"low bq, low freq, many artifacts, many samples",UPN2_044,12,11992207,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys99Asn/c.297A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),2532,34,2581,"0,0131731887",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,0,Damaging,"32,27","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_045,12,11992207,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys99Asn/c.297A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),7618,99,7777,"0,0127298444",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,0,Damaging,"32,09","16,55"
"low bq, low freq, many artifacts, many samples",UPN2_046,12,11992207,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys99Asn/c.297A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),10367,122,10570,"0,0115421003",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,0,Damaging,"31,99","16,88"
"low bq, low freq, many artifacts, many samples",UPN2_047,12,11992207,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys99Asn/c.297A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),12692,149,12931,"0,0115226974",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,0,Damaging,"32,06","17,49"
"low bq, low freq, many artifacts, many samples",UPN2_048,12,11992207,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys99Asn/c.297A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),3985,43,4048,"0,0106225296",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,0,Damaging,"32,08","17,86"
"low bq, low freq, many artifacts, many samples",UPN2_049,12,11992207,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys99Asn/c.297A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),9685,104,9857,"0,0105508775",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,0,Damaging,"31,94","17,24"
"low bq, low freq, many artifacts, many samples",UPN2_050,12,11992207,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys99Asn/c.297A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),8658,108,8818,"0,0122476752",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,0,Damaging,"31,84","18,57"
"low bq, low freq, many artifacts, many samples",UPN2_051,12,11992207,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys99Asn/c.297A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),9402,101,9575,"0,0105483029",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,0,Damaging,"32,18","16,12"
"low bq, low freq, many artifacts, many samples",UPN2_052,12,11992207,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys99Asn/c.297A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),6975,79,7106,"0,0111173656",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,0,Damaging,"31,98","16,44"
"low bq, low freq, many artifacts, many samples",UPN2_053,12,11992207,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys99Asn/c.297A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),11114,122,11315,"0,0107821476",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,0,Damaging,"31,84","16,94"
"low bq, low freq, many artifacts, many samples",UPN2_054,12,11992207,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys99Asn/c.297A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),8756,97,8940,"0,0108501119",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,0,Damaging,"31,94","17,33"
"low bq, low freq, many artifacts, many samples",UPN2_055,12,11992207,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys99Asn/c.297A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),11097,117,11272,"0,0103797019",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,0,Damaging,"32,08","15,85"
"low bq, low freq, many artifacts, many samples",UPN2_057,12,11992207,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys99Asn/c.297A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),11856,152,12075,"0,0125879917",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,0,Damaging,"31,98","17,41"
"low bq, low freq, many artifacts, many samples",UPN2_058,12,11992207,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys99Asn/c.297A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),11918,123,12114,"0,0101535414",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,0,Damaging,"32,05","17,24"
"low bq, low freq, many artifacts",UPN2_013,12,11992207,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys99Asn/c.297A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),5345,56,5423,"0,0103263876",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,27",Deleterious,0,Damaging,"32,54","19,75"
"inspected, low bq, bad alignment",UPN2_041,12,11992208,G,A,missense_variant(MODERATE|MISSENSE|Gag/Aag|p.Glu100Lys/c.298G>A|452|ETV6|protein_coding|CODING|ENST00000396373|3|A),453,44,498,"0,0883534137",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,91",Deleterious,"0,007",Damaging,"34,32","29,82"
"low freq, many artifacts",UPN2_044,12,11992209,A,G,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu100Gly/c.299A>G|452|ETV6|protein_coding|CODING|ENST00000396373|3|G),2532,29,2582,"0,0112316034",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,23",Deleterious,"0,004",Damaging,"33,34","32,41"
"low bq, low freq, many artifacts",UPN2_057,12,11992212,A,T,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp101Val/c.302A>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),11919,125,12081,"0,0103468256",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,69",Deleterious,3,Damaging,"33,84","19,18"
"low freq, many artifacts",UPN2_056,12,11992223,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg105Gly/c.313C>G|452|ETV6|protein_coding|CODING|ENST00000396373|3|G),3560,62,3634,"0,0170610897",0,0,0,0,1,0,0,1,2,NO,NO,COSM306115,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,"0,014",Damaging,"33,79","32,19"
"low freq, many artifacts",UPN2_006,12,11992236,C,T,missense_variant(MODERATE|MISSENSE|tCa/tTa|p.Ser109Leu/c.326C>T|452|ETV6|protein_coding|CODING|ENST00000396373|3|T),7258,94,7367,"0,0127596036",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,"0,013",Damaging,"34,25","35,04"
"low freq, many artifacts",UPN2_044,12,12006364,A,G,missense_variant(MODERATE|MISSENSE|gAt/gGt|p.Asp111Gly/c.332A>G|452|ETV6|protein_coding|CODING|ENST00000396373|4|G),3257,37,3323,"0,011134517",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,"0,003",Damaging,"35,59","34,95"
"low freq, many artifacts",UPN2_056,12,12006400,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln123Leu/c.368A>T|452|ETV6|protein_coding|CODING|ENST00000396373|4|T),4309,52,4372,"0,0118938701",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,23",Deleterious,"0,001",Damaging,"35,07","32,81"
"low freq, many artifacts",UPN2_003,12,12006418,T,C,missense_variant(MODERATE|MISSENSE|cTt/cCt|p.Leu129Pro/c.386T>C|452|ETV6|protein_coding|CODING|ENST00000396373|4|C),1924,21,1955,"0,010741688",0,0,0,0,1,0,0,1,2,NO,NO,COSM4039283,stomach,1,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,"0,018",Damaging,"34,87","31,76"
"low freq, many artifacts",UPN2_053,12,12006418,T,C,missense_variant(MODERATE|MISSENSE|cTt/cCt|p.Leu129Pro/c.386T>C|452|ETV6|protein_coding|CODING|ENST00000396373|4|C),14481,152,14736,"0,0103148751",0,0,0,0,1,0,0,0,1,NO,NO,COSM4039283,stomach,1,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,18,Damaging,35,"32,94"
"low freq, many artifacts",UPN2_044,12,12006421,T,C,missense_variant(MODERATE|MISSENSE|tTt/tCt|p.Phe130Ser/c.389T>C|452|ETV6|protein_coding|CODING|ENST00000396373|4|C),3274,42,3323,"0,0126391815",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,"0,181",Tolerated,"35,01","33,64"
"low freq, many artifacts",UPN2_044,12,12006451,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile140Lys/c.419T>A|452|ETV6|protein_coding|CODING|ENST00000396373|4|A),6464,90,6566,"0,0137069753",0,0,0,0,0,1,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,004",Damaging,"32,19","30,31"
"low freq, many artifacts, many samples",UPN2_001,12,12006451,TAC,T,frameshift_variant(HIGH||cag/|p.Gln143fs/c.427_428delCA|452|ETV6|protein_coding|CODING|ENST00000396373|4|T|INFO_REALIGN_3_PRIME);LOF=(ETV6|ENSG00000139083|5|0,13842,155,14075,"0,0110124334",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,39",NA
"low freq, many artifacts, many samples",UPN2_044,12,12006451,TAC,T,frameshift_variant(HIGH||cag/|p.Gln143fs/c.427_428delCA|452|ETV6|protein_coding|CODING|ENST00000396373|4|T|INFO_REALIGN_3_PRIME);LOF=(ETV6|ENSG00000139083|5|0,6438,69,6566,"0,0105086811",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,44",NA
"low freq, many artifacts, many samples",UPN2_046,12,12006451,TAC,T,frameshift_variant(HIGH||cag/|p.Gln143fs/c.427_428delCA|452|ETV6|protein_coding|CODING|ENST00000396373|4|T|INFO_REALIGN_3_PRIME);LOF=(ETV6|ENSG00000139083|5|0,25389,263,25836,"0,0101795944",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,38",NA
"low freq, many artifacts, many samples",UPN2_034,12,12006451,TAC,T,frameshift_variant(HIGH||cag/|p.Gln143fs/c.427_428delCA|452|ETV6|protein_coding|CODING|ENST00000396373|4|T|INFO_REALIGN_3_PRIME);LOF=(ETV6|ENSG00000139083|5|0,6317,84,6424,"0,0130759651",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,03",NA
"low freq, many artifacts, many samples",UPN2_035,12,12006451,TAC,T,frameshift_variant(HIGH||cag/|p.Gln143fs/c.427_428delCA|452|ETV6|protein_coding|CODING|ENST00000396373|4|T|INFO_REALIGN_3_PRIME);LOF=(ETV6|ENSG00000139083|5|0,53369,563,54230,"0,0103817075",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,1",NA
"low freq, many artifacts, many samples",UPN2_036,12,12006451,TAC,T,frameshift_variant(HIGH||cag/|p.Gln143fs/c.427_428delCA|452|ETV6|protein_coding|CODING|ENST00000396373|4|T|INFO_REALIGN_3_PRIME);LOF=(ETV6|ENSG00000139083|5|0,43435,463,44113,"0,0104957722",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,08",NA
"low freq, many artifacts, many samples",UPN2_006,12,12006451,TAC,T,frameshift_variant(HIGH||cag/|p.Gln143fs/c.427_428delCA|452|ETV6|protein_coding|CODING|ENST00000396373|4|T|INFO_REALIGN_3_PRIME);LOF=(ETV6|ENSG00000139083|5|0,17943,248,18274,"0,013571194",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,36",NA
"low freq, many artifacts, many samples",UPN2_054,12,12006451,TAC,T,frameshift_variant(HIGH||cag/|p.Gln143fs/c.427_428delCA|452|ETV6|protein_coding|CODING|ENST00000396373|4|T|INFO_REALIGN_3_PRIME);LOF=(ETV6|ENSG00000139083|5|0,21248,248,21629,"0,0114660872",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,39",NA
"low freq, many artifacts, many samples",UPN2_009,12,12006451,TAC,T,frameshift_variant(HIGH||cag/|p.Gln143fs/c.427_428delCA|452|ETV6|protein_coding|CODING|ENST00000396373|4|T|INFO_REALIGN_3_PRIME);LOF=(ETV6|ENSG00000139083|5|0,44655,474,45364,"0,010448814",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,39",NA
"low freq, many artifacts, many samples",UPN2_012,12,12006451,TAC,T,frameshift_variant(HIGH||cag/|p.Gln143fs/c.427_428delCA|452|ETV6|protein_coding|CODING|ENST00000396373|4|T|INFO_REALIGN_3_PRIME);LOF=(ETV6|ENSG00000139083|5|0,17795,200,18116,"0,0110399647",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,39",NA
"low freq, many artifacts",UPN2_065,12,12006451,TAC,T,frameshift_variant(HIGH||cag/|p.Gln143fs/c.427_428delCA|452|ETV6|protein_coding|CODING|ENST00000396373|4|T|INFO_REALIGN_3_PRIME),23765,246,24154,"0,0101846485",0,0,0,0,1,0,0,0,1,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,"33,11",NA
"low freq, many artifacts, many samples",UPN2_080,12,12006451,TAC,T,frameshift_variant(HIGH||cag/|p.Gln143fs/c.427_428delCA|452|ETV6|protein_coding|CODING|ENST00000396373|4|T|INFO_REALIGN_3_PRIME);LOF=(ETV6|ENSG00000139083|5|0,22332,230,22699,"0,010132605",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,33,NA
"low freq, many artifacts, many samples",UPN2_095,12,12006451,TAC,T,frameshift_variant(HIGH||cag/|p.Gln143fs/c.427_428delCA|452|ETV6|protein_coding|CODING|ENST00000396373|4|T|INFO_REALIGN_3_PRIME);LOF=(ETV6|ENSG00000139083|5|0,13921,149,14124,"0,0105494194",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,18",NA
"low freq, many artifacts, many samples",UPN2_105,12,12006451,TAC,T,frameshift_variant(HIGH||cag/|p.Gln143fs/c.427_428delCA|452|ETV6|protein_coding|CODING|ENST00000396373|4|T|INFO_REALIGN_3_PRIME);LOF=(ETV6|ENSG00000139083|5|0,12266,130,12436,"0,010453522",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,2",NA
"low freq, many artifacts, many samples",UPN2_044,12,12006456,A,T,missense_variant(MODERATE|MISSENSE|Aca/Tca|p.Thr142Ser/c.424A>T|452|ETV6|protein_coding|CODING|ENST00000396373|4|T),6442,103,6569,"0,0156797077",0,0,0,0,0,0,0,1,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,63",Neutral,824,Tolerated,"32,76","27,3"
"low bq, low freq, many artifacts, many samples",UPN2_048,12,12006456,A,T,missense_variant(MODERATE|MISSENSE|Aca/Tca|p.Thr142Ser/c.424A>T|452|ETV6|protein_coding|CODING|ENST00000396373|4|T),5901,72,5991,"0,012018027",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,63",Neutral,824,Tolerated,"32,61","24,92"
"low freq, many artifacts, many samples",UPN2_048,12,12006463,C,T,missense_variant(MODERATE|MISSENSE|cCg/cTg|p.Pro144Leu/c.431C>T|452|ETV6|protein_coding|CODING|ENST00000396373|4|T),5893,74,6000,"0,0123333333",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,"0,326",Tolerated,"29,79","33,14"
"low freq, many artifacts",UPN2_001,12,12006472,T,TA,frameshift_variant(HIGH||ctg/Actg|p.Leu148fs/c.441dupA|452|ETV6|protein_coding|CODING|ENST00000396373|4|TA|INFO_REALIGN_3_PRIME);LOF=(ETV6|ENSG00000139083|5|0,14022,196,14093,"0,0139076137",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,36",NA
"low bq, low freq, many artifacts, many samples",UPN2_048,12,12006487,A,T,missense_variant(MODERATE|MISSENSE|cAt/cTt|p.His152Leu/c.455A>T|452|ETV6|protein_coding|CODING|ENST00000396373|4|T),2928,41,2973,"0,0137907837",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,68",Deleterious,474,Tolerated,"33,57","23,59"
"low freq, many artifacts",UPN2_048,12,12022364,G,A,missense_variant(MODERATE|MISSENSE|tGt/tAt|p.Cys157Tyr/c.470G>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),3155,37,3193,"0,0115878484",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,1,Tolerated,"35,29",36
"low freq, many artifacts",UPN2_048,12,12022372,A,G,missense_variant(MODERATE|MISSENSE|Agg/Ggg|p.Arg160Gly/c.478A>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),3150,37,3193,"0,0115878484",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,"0,24",Tolerated,"33,93","35,3"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,12,12022375,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr161Pro/c.481A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4887,64,4968,"0,0128824477",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,38",Neutral,334,Tolerated,"26,32","14,92"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,12,12022375,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr161Pro/c.481A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4875,61,4956,"0,0123083132",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,38",Neutral,334,Tolerated,"26,11","15,69"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_066,12,12022375,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr161Pro/c.481A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4368,46,4434,"0,0103743798",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,38",Neutral,334,Tolerated,"26,45","16,07"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_068,12,12022375,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr161Pro/c.481A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4853,57,4924,"0,0115759545",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,38",Neutral,334,Tolerated,"25,91","14,81"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_069,12,12022375,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr161Pro/c.481A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5591,72,5691,"0,0126515551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,38",Neutral,334,Tolerated,"26,15","15,89"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_070,12,12022375,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr161Pro/c.481A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3350,41,3405,"0,012041116",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,38",Neutral,334,Tolerated,"26,32","15,8"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,12,12022375,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr161Pro/c.481A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3993,41,4050,"0,0101234568",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,38",Neutral,334,Tolerated,"26,29","14,68"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,12,12022375,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr161Pro/c.481A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5889,60,5968,"0,0100536193",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,38",Neutral,334,Tolerated,"26,33","14,88"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,12,12022375,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr161Pro/c.481A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4925,52,4995,"0,0104104104",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,38",Neutral,334,Tolerated,"26,32","15,1"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,12,12022375,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr161Pro/c.481A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2784,42,2837,"0,0148043708",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,38",Neutral,334,Tolerated,"26,37","14,83"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_075,12,12022375,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr161Pro/c.481A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6604,72,6697,"0,0107510826",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,38",Neutral,334,Tolerated,"26,44","15,97"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,12,12022375,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr161Pro/c.481A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5078,61,5155,"0,0118331717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,38",Neutral,334,Tolerated,"26,46","15,05"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,12,12022375,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr161Pro/c.481A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5272,61,5357,"0,0113869703",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,38",Neutral,334,Tolerated,"26,31","15,16"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,12,12022375,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr161Pro/c.481A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5050,67,5137,"0,0130426319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,38",Neutral,334,Tolerated,"26,29","15,57"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,12,12022375,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr161Pro/c.481A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5327,61,5408,"0,0112795858",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,38",Neutral,334,Tolerated,"26,23","14,92"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_081,12,12022375,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr161Pro/c.481A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7574,78,7683,"0,0101522843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,38",Neutral,334,Tolerated,"26,57","16,05"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,12,12022375,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr161Pro/c.481A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5747,63,5836,"0,0107950651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,38",Neutral,334,Tolerated,"26,04","15,97"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,12,12022375,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr161Pro/c.481A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5791,65,5877,"0,0110600647",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,38",Neutral,334,Tolerated,"26,15","15,38"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_085,12,12022375,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr161Pro/c.481A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3855,49,3922,"0,0124936257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,38",Neutral,334,Tolerated,"26,17","15,16"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,12,12022375,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr161Pro/c.481A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3038,34,3081,"0,0110353781",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,38",Neutral,334,Tolerated,"26,4","15,56"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_087,12,12022375,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr161Pro/c.481A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5791,71,5887,"0,0120604722",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,38",Neutral,334,Tolerated,"26,32","14,59"
"low bq, bad alignment, low freq, many artifacts",UPN2_088,12,12022375,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr161Pro/c.481A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4592,54,4672,"0,0115582192",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,38",Neutral,334,Tolerated,"26,4","16,13"
"low freq, many artifacts",UPN2_044,12,12022390,G,A,missense_variant(MODERATE|MISSENSE|Gtg/Atg|p.Val166Met/c.496G>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),2824,30,2854,"0,0105115627",0,0,0,0,1,0,0,1,2,0,0,NO,NA,NA,NO,rs142603082,NO,NA,NO,YES,"-0,34",Neutral,"0,128",Tolerated,"34,72","35,13"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,12,12022403,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His170Pro/c.509A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5461,64,5573,"0,0114839404",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,326,Tolerated,"23,64","14,59"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,12,12022403,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His170Pro/c.509A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5760,63,5860,"0,0107508532",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,326,Tolerated,"23,61","14,63"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_065,12,12022403,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His170Pro/c.509A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3712,46,3787,"0,0121468181",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,326,Tolerated,"24,09","14,93"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_068,12,12022403,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His170Pro/c.509A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4823,53,4915,"0,0107833164",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,326,Tolerated,"23,39","14,91"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_070,12,12022403,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His170Pro/c.509A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3335,42,3401,"0,012349309",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,326,Tolerated,"23,74","15,79"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,12,12022403,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His170Pro/c.509A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3967,44,4047,"0,0108722511",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,326,Tolerated,"23,65","14,3"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,12,12022403,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His170Pro/c.509A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5857,66,5958,"0,0110775428",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,326,Tolerated,"23,73","14,21"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,12,12022403,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His170Pro/c.509A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5049,65,5148,"0,0126262626",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,326,Tolerated,"23,68",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,12,12022403,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His170Pro/c.509A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5021,73,5130,"0,0142300195",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,326,Tolerated,"23,49","15,04"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_079,12,12022403,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His170Pro/c.509A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2603,33,2654,"0,0124340618",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,326,Tolerated,"23,65","15,21"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,12,12022403,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His170Pro/c.509A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5306,67,5401,"0,0124051102",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,326,Tolerated,"23,81","14,93"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_082,12,12022403,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His170Pro/c.509A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4677,53,4753,"0,0111508521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,326,Tolerated,"23,73","15,34"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,12,12022403,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His170Pro/c.509A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5725,69,5827,"0,0118414278",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,326,Tolerated,"23,25","14,1"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,12,12022403,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His170Pro/c.509A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5773,67,5873,"0,0114081389",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,326,Tolerated,"23,56","14,33"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_085,12,12022403,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His170Pro/c.509A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3840,46,3916,"0,0117466803",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,326,Tolerated,"23,88","14,28"
"low bq, bad alignment, low freq, many artifacts",UPN2_088,12,12022403,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His170Pro/c.509A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4580,55,4667,"0,0117848725",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,326,Tolerated,"23,93","14,8"
"low freq, many artifacts",UPN2_044,12,12022406,A,T,missense_variant(MODERATE|MISSENSE|cAt/cTt|p.His171Leu/c.512A>T|452|ETV6|protein_coding|CODING|ENST00000396373|5|T),2793,49,2851,"0,0171869519",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,43",Neutral,"0,915",Tolerated,"33,44","33,33"
"low bq, bad alignment, many samples",UPN2_059,12,12022409,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn172Thr/c.515A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4624,125,4777,"0,0261670505",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,88",Neutral,33,Damaging,"22,29","14,27"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_060,12,12022409,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn172Thr/c.515A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4107,85,4207,"0,0202044212",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,88",Neutral,33,Damaging,"22,18","14,84"
"low bq, bad alignment, many samples",UPN2_061,12,12022409,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn172Thr/c.515A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4794,150,4960,"0,0302419355",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,88",Neutral,33,Damaging,"22,01","14,47"
"low bq, bad alignment, many samples",UPN2_062,12,12022409,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn172Thr/c.515A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5398,136,5565,"0,0244384546",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,88",Neutral,33,Damaging,"21,77","14,24"
"low bq, bad alignment, many samples",UPN2_063,12,12022409,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn172Thr/c.515A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4792,121,4945,"0,0244691608",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,88",Neutral,33,Damaging,"21,88","14,74"
"low bq, bad alignment, many samples",UPN2_064,12,12022409,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn172Thr/c.515A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5690,136,5854,"0,0232319781",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,88",Neutral,33,Damaging,"22,02","14,31"
"low bq, bad alignment, many samples",UPN2_065,12,12022409,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn172Thr/c.515A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3663,92,3782,"0,0243257536",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,88",Neutral,33,Damaging,"22,16","14,15"
"low bq, bad alignment, many samples",UPN2_066,12,12022409,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn172Thr/c.515A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4291,117,4422,"0,026458616",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,88",Neutral,33,Damaging,"21,9","14,53"
"low bq, bad alignment, many samples",UPN2_067,12,12022409,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn172Thr/c.515A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5742,149,5924,"0,0251519244",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,88",Neutral,33,Damaging,"22,43","15,09"
"low bq, bad alignment, many samples",UPN2_068,12,12022409,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn172Thr/c.515A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4753,133,4909,"0,0270930943",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,88",Neutral,33,Damaging,"21,75","14,19"
"low bq, bad alignment, many samples",UPN2_069,12,12022409,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn172Thr/c.515A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5475,174,5673,"0,0306716023",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,88",Neutral,33,Damaging,"21,98","14,24"
"low bq, bad alignment, many samples",UPN2_070,12,12022409,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn172Thr/c.515A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3273,109,3400,"0,0320588235",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,88",Neutral,33,Damaging,"21,59","14,3"
"low bq, bad alignment, many samples",UPN2_071,12,12022409,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn172Thr/c.515A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3919,108,4043,"0,026712837",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,88",Neutral,33,Damaging,"21,82","14,49"
"low bq, bad alignment, many samples",UPN2_072,12,12022409,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn172Thr/c.515A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5773,149,5952,"0,0250336022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,88",Neutral,33,Damaging,"21,98","14,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,12,12022409,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn172Thr/c.515A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4869,95,4983,"0,0190648204",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,88",Neutral,33,Damaging,"22,19","14,45"
"low bq, bad alignment, many samples",UPN2_074,12,12022409,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn172Thr/c.515A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2748,71,2832,"0,0250706215",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,88",Neutral,33,Damaging,"21,72","14,51"
"low bq, bad alignment, many samples",UPN2_075,12,12022409,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn172Thr/c.515A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6498,151,6684,"0,0225912627",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,88",Neutral,33,Damaging,"22,48","14,47"
"low bq, bad alignment, many samples",UPN2_076,12,12022409,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn172Thr/c.515A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4955,155,5137,"0,0301732529",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,88",Neutral,33,Damaging,"21,55","14,17"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,12,12022409,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn172Thr/c.515A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5208,117,5349,"0,0218732473",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,88",Neutral,33,Damaging,"22,05","14,38"
"low bq, bad alignment, many samples",UPN2_078,12,12022409,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn172Thr/c.515A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4958,143,5128,"0,0278861154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,88",Neutral,33,Damaging,"21,77","14,54"
"low bq, bad alignment, many samples",UPN2_079,12,12022409,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn172Thr/c.515A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2570,68,2653,"0,0256313607",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,88",Neutral,33,Damaging,"21,75",14
"low bq, bad alignment, many samples",UPN2_080,12,12022409,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn172Thr/c.515A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5247,119,5392,"0,0220697329",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,88",Neutral,33,Damaging,"21,76","14,85"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_081,12,12022409,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn172Thr/c.515A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7475,146,7665,"0,019047619",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,88",Neutral,33,Damaging,"22,26","14,67"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_082,12,12022409,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn172Thr/c.515A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4623,92,4744,"0,0193929174",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,88",Neutral,33,Damaging,"22,02","14,24"
"low bq, bad alignment, many samples",UPN2_083,12,12022409,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn172Thr/c.515A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5650,141,5819,"0,0242309675",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,88",Neutral,33,Damaging,"21,49","14,45"
"low bq, bad alignment, many samples",UPN2_084,12,12022409,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn172Thr/c.515A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5678,152,5863,"0,0259252942",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,88",Neutral,33,Damaging,"21,65","14,3"
"low bq, bad alignment, many samples",UPN2_085,12,12022409,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn172Thr/c.515A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3792,93,3915,"0,0237547893",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,88",Neutral,33,Damaging,"22,16","14,58"
"low bq, bad alignment, many samples",UPN2_086,12,12022409,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn172Thr/c.515A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2984,78,3073,"0,0253823625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,88",Neutral,33,Damaging,"21,82","14,23"
"low bq, bad alignment, many samples",UPN2_087,12,12022409,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn172Thr/c.515A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5684,162,5874,"0,0275791624",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,88",Neutral,33,Damaging,"21,74","14,49"
"low bq, bad alignment",UPN2_088,12,12022409,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn172Thr/c.515A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4517,116,4659,"0,0248980468",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,88",Neutral,33,Damaging,"21,96","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_059,12,12022417,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr175Pro/c.523A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4707,48,4776,"0,0100502513",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,4,Damaging,"27,01",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_060,12,12022417,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr175Pro/c.523A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4146,49,4204,"0,0116555661",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,4,Damaging,"26,82","14,41"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,12,12022417,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr175Pro/c.523A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4870,59,4958,"0,0118999597",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,4,Damaging,"26,75","15,36"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,12,12022417,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr175Pro/c.523A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5476,61,5564,"0,0109633357",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,4,Damaging,"26,64","15,31"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,12,12022417,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr175Pro/c.523A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5752,71,5850,"0,0121367521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,4,Damaging,"26,78","14,8"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_065,12,12022417,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr175Pro/c.523A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3732,42,3782,"0,0111052353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,4,Damaging,"26,9","14,43"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_066,12,12022417,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr175Pro/c.523A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4327,58,4419,"0,0131251414",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,4,Damaging,"26,88","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_067,12,12022417,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr175Pro/c.523A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5834,61,5923,"0,010298835",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,4,Damaging,"27,16","14,77"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_068,12,12022417,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr175Pro/c.523A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4824,65,4908,"0,0132436838",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,4,Damaging,"26,51","15,05"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_069,12,12022417,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr175Pro/c.523A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5568,77,5672,"0,0135754584",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,4,Damaging,"26,79","15,48"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_070,12,12022417,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr175Pro/c.523A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3322,52,3399,"0,0152986172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,4,Damaging,"26,55","14,87"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,12,12022417,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr175Pro/c.523A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3968,62,4042,"0,0153389411",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,4,Damaging,"26,68","15,44"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,12,12022417,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr175Pro/c.523A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5858,70,5950,"0,0117647059",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,4,Damaging,"26,7","15,3"
"low bq, low freq, many artifacts, many samples",UPN2_073,12,12022417,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr175Pro/c.523A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4897,66,4978,"0,0132583367",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,4,Damaging,"27,29","14,7"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,12,12022417,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr175Pro/c.523A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2782,36,2829,"0,0127253446",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,4,Damaging,"26,51",15
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,12,12022417,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr175Pro/c.523A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5053,65,5136,"0,0126557632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,4,Damaging,"26,55","14,78"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,12,12022417,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr175Pro/c.523A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5260,58,5346,"0,0108492331",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,4,Damaging,"26,7","14,43"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,12,12022417,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr175Pro/c.523A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5028,69,5126,"0,0134607881",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,4,Damaging,"26,72","14,88"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_079,12,12022417,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr175Pro/c.523A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2607,41,2653,"0,0154542028",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,4,Damaging,"26,93","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_082,12,12022417,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr175Pro/c.523A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4667,54,4743,"0,0113851992",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,4,Damaging,"27,25","14,46"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,12,12022417,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr175Pro/c.523A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5733,62,5818,"0,010656583",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,4,Damaging,"26,38","15,24"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,12,12022417,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr175Pro/c.523A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5736,92,5861,"0,01569698",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,4,Damaging,"26,6","15,3"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_085,12,12022417,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr175Pro/c.523A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3840,55,3915,"0,0140485313",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,4,Damaging,"26,84","14,95"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,12,12022417,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr175Pro/c.523A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3029,33,3073,"0,0107386918",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,4,Damaging,"26,4","14,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_087,12,12022417,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr175Pro/c.523A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5767,82,5874,"0,0139598229",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,4,Damaging,"26,8","14,79"
"low bq, low freq, many artifacts",UPN2_088,12,12022417,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr175Pro/c.523A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4578,60,4658,"0,0128810648",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,4,Damaging,"27,1","15,42"
"low freq, many artifacts",UPN2_048,12,12022432,C,T,missense_variant(MODERATE|MISSENSE|Cac/Tac|p.His180Tyr/c.538C>T|452|ETV6|protein_coding|CODING|ENST00000396373|5|T),3137,39,3180,"0,0122641509",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,17",Neutral,"0,003",Damaging,"34,31","34,36"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_059,12,12022433,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His180Pro/c.539A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4657,92,4776,"0,0192629816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,7,Damaging,"25,5","15,09"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_060,12,12022433,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His180Pro/c.539A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4098,80,4204,"0,0190294957",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,7,Damaging,"25,56","15,09"
"low bq, bad alignment, many samples",UPN2_061,12,12022433,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His180Pro/c.539A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4802,133,4957,"0,0268307444",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,7,Damaging,"25,3","14,6"
"low bq, bad alignment, many samples",UPN2_062,12,12022433,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His180Pro/c.539A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5400,136,5561,"0,0244560331",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,7,Damaging,"24,88","15,32"
"low bq, bad alignment, many samples",UPN2_063,12,12022433,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His180Pro/c.539A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4800,117,4938,"0,0236938032",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,7,Damaging,"24,9","14,23"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,12,12022433,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His180Pro/c.539A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5662,127,5846,"0,0217242559",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,7,Damaging,"25,02","15,6"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_065,12,12022433,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His180Pro/c.539A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3685,70,3780,"0,0185185185",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,7,Damaging,"25,03","15,57"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_066,12,12022433,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His180Pro/c.539A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4312,83,4417,"0,0187910346",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,7,Damaging,"25,08","14,67"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_067,12,12022433,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His180Pro/c.539A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5774,115,5920,"0,0194256757",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,7,Damaging,"25,52","14,57"
"low bq, bad alignment, many samples",UPN2_068,12,12022433,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His180Pro/c.539A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4772,114,4906,"0,0232368528",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,7,Damaging,"24,82","14,71"
"low bq, bad alignment, many samples",UPN2_069,12,12022433,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His180Pro/c.539A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5497,139,5669,"0,0245193156",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,7,Damaging,"25,21","14,73"
"low bq, bad alignment, many samples",UPN2_070,12,12022433,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His180Pro/c.539A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3298,84,3397,"0,0247277009",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,7,Damaging,"24,93","14,92"
"low bq, bad alignment, many samples",UPN2_071,12,12022433,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His180Pro/c.539A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3912,106,4042,"0,0262246413",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,7,Damaging,"25,3",15
"low bq, bad alignment, many samples",UPN2_072,12,12022433,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His180Pro/c.539A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5779,133,5948,"0,0223604573",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,7,Damaging,"25,18","14,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,12,12022433,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His180Pro/c.539A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4859,92,4975,"0,0184924623",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,7,Damaging,"25,14","14,36"
"low bq, bad alignment, many samples",UPN2_074,12,12022433,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His180Pro/c.539A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2744,66,2826,"0,0233545648",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,7,Damaging,"25,23","15,41"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_075,12,12022433,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His180Pro/c.539A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6507,128,6675,"0,01917603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,7,Damaging,"25,67","14,68"
"low bq, bad alignment, many samples",UPN2_076,12,12022433,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His180Pro/c.539A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4973,118,5133,"0,0229885057",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,7,Damaging,"24,88","15,22"
"low bq, bad alignment, many samples",UPN2_077,12,12022433,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His180Pro/c.539A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5190,120,5344,"0,0224550898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,7,Damaging,"25,16","14,75"
"low bq, bad alignment, many samples",UPN2_078,12,12022433,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His180Pro/c.539A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4963,135,5124,"0,0263466042",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,7,Damaging,"24,92","14,42"
"low bq, bad alignment, many samples",UPN2_079,12,12022433,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His180Pro/c.539A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2553,82,2653,"0,0309084056",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,7,Damaging,"25,13","14,77"
"low bq, bad alignment, many samples",UPN2_080,12,12022433,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His180Pro/c.539A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5242,129,5389,"0,0239376508",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,7,Damaging,"24,98","14,43"
"low bq, bad alignment, many samples",UPN2_081,12,12022433,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His180Pro/c.539A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7433,182,7659,"0,0237628933",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,7,Damaging,"25,39","14,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_082,12,12022433,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His180Pro/c.539A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4600,101,4742,"0,0212990299",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,7,Damaging,"25,21","14,49"
"low bq, bad alignment, many samples",UPN2_083,12,12022433,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His180Pro/c.539A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5635,147,5813,"0,0252881473",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,7,Damaging,"24,85","14,56"
"low bq, bad alignment, many samples",UPN2_084,12,12022433,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His180Pro/c.539A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5677,142,5859,"0,0242362178",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,7,Damaging,"24,79","14,8"
"low bq, bad alignment, many samples",UPN2_085,12,12022433,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His180Pro/c.539A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3806,90,3915,"0,0229885057",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,7,Damaging,"25,03","14,46"
"low bq, bad alignment, many samples",UPN2_086,12,12022433,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His180Pro/c.539A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2965,89,3072,"0,0289713542",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,7,Damaging,"24,83","15,06"
"low bq, bad alignment, many samples",UPN2_087,12,12022433,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His180Pro/c.539A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5695,145,5871,"0,0246976665",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,7,Damaging,"25,14","14,32"
"low bq, bad alignment",UPN2_088,12,12022433,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His180Pro/c.539A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4503,117,4653,"0,0251450677",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,7,Damaging,"25,36","14,71"
"low freq, many artifacts",UPN2_048,12,12022435,C,T,missense_variant(MODERATE|MISSENSE|Cgc/Tgc|p.Arg181Cys/c.541C>T|452|ETV6|protein_coding|CODING|ENST00000396373|5|T),3126,46,3180,"0,0144654088",0,0,0,0,1,0,0,1,2,NO,"0,001",COSM4039331,stomach,1,NO,rs149660037,NO,"2,47E-005",NO,NO,"-2,41",Neutral,"0,002",Damaging,"34,08","34,74"
"low freq, many artifacts",UPN2_048,12,12022445,CA,C,frameshift_variant(HIGH||tca/|p.Pro185fs/c.552delA|452|ETV6|protein_coding|CODING|ENST00000396373|5|C);LOF=(ETV6|ENSG00000139083|5|0,3087,33,3178,"0,0103838892",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,66",NA
"low bq, low freq, many artifacts, many samples",UPN2_001,12,12022451,T,A,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile186Asn/c.557T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),2988,34,3031,"0,01121742",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,"0,14",Tolerated,"32,77","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_014,12,12022451,T,A,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile186Asn/c.557T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),4741,58,4821,"0,012030699",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,"0,14",Tolerated,"32,15","16,21"
"low bq, low freq, many artifacts, many samples",UPN2_015,12,12022451,T,A,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile186Asn/c.557T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),7495,80,7616,"0,0105042017",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,"0,14",Tolerated,"32,2","16,92"
"low bq, low freq, many artifacts, many samples",UPN2_017,12,12022451,T,A,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile186Asn/c.557T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),2127,23,2160,"0,0106481481",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,"0,14",Tolerated,"32,17","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_019,12,12022451,T,A,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile186Asn/c.557T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),4117,55,4185,"0,0131421744",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,"0,14",Tolerated,"32,17","16,35"
"low bq, low freq, many artifacts, many samples",UPN2_020,12,12022451,T,A,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile186Asn/c.557T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),2405,26,2451,"0,0106079151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,"0,14",Tolerated,"32,19","16,88"
"low bq, low freq, many artifacts, many samples",UPN2_002,12,12022451,T,A,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile186Asn/c.557T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),3682,53,3744,"0,0141559829",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,"0,14",Tolerated,"32,94",14
"low bq, low freq, many artifacts, many samples",UPN2_022,12,12022451,T,A,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile186Asn/c.557T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),5721,58,5796,"0,0100069013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,"0,14",Tolerated,"32,31","15,48"
"low bq, low freq, many artifacts, many samples",UPN2_026,12,12022451,T,A,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile186Asn/c.557T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),5980,65,6071,"0,0107066381",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,"0,14",Tolerated,"32,08","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_027,12,12022451,T,A,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile186Asn/c.557T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),7478,81,7590,"0,0106719368",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,"0,14",Tolerated,"32,12","15,31"
"low bq, low freq, many artifacts, many samples",UPN2_042,12,12022451,T,A,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile186Asn/c.557T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),9441,100,9602,"0,010414497",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,"0,14",Tolerated,"33,51","16,68"
"low bq, low freq, many artifacts, many samples",UPN2_028,12,12022451,T,A,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile186Asn/c.557T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),5649,69,5736,"0,0120292887",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,"0,14",Tolerated,"32,21","16,83"
"low bq, low freq, many artifacts, many samples",UPN2_043,12,12022451,T,A,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile186Asn/c.557T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),5774,62,5868,"0,0105657805",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,"0,14",Tolerated,"33,27","17,6"
"low bq, low freq, many artifacts, many samples",UPN2_044,12,12022451,T,A,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile186Asn/c.557T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),2917,33,2959,"0,0111524164",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,"0,14",Tolerated,"33,35","17,61"
"low bq, low freq, many artifacts, many samples",UPN2_029,12,12022451,T,A,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile186Asn/c.557T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),4637,57,4711,"0,012099342",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,"0,14",Tolerated,"32,16","16,19"
"low bq, low freq, many artifacts, many samples",UPN2_032,12,12022451,T,A,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile186Asn/c.557T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),2132,26,2164,"0,0120147874",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,"0,14",Tolerated,"32,31","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_046,12,12022451,T,A,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile186Asn/c.557T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),8928,119,9090,"0,0130913091",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,"0,14",Tolerated,"33,13","16,78"
"low bq, low freq, many artifacts, many samples",UPN2_048,12,12022451,T,A,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile186Asn/c.557T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),3318,38,3365,"0,0112927192",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,"0,14",Tolerated,"33,18","15,87"
"low bq, low freq, many artifacts, many samples",UPN2_006,12,12022451,T,A,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile186Asn/c.557T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),4276,49,4364,"0,011228231",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,"0,14",Tolerated,"32,98","15,53"
"low bq, low freq, many artifacts, many samples",UPN2_049,12,12022451,T,A,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile186Asn/c.557T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),7051,87,7171,"0,0121321991",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,"0,14",Tolerated,"33,38","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_050,12,12022451,T,A,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile186Asn/c.557T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),7718,90,7855,"0,0114576703",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,"0,14",Tolerated,"33,47","18,28"
"low bq, low freq, many artifacts, many samples",UPN2_052,12,12022451,T,A,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile186Asn/c.557T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),6367,66,6461,"0,010215137",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,"0,14",Tolerated,"33,39","17,45"
"low bq, low freq, many artifacts, many samples",UPN2_053,12,12022451,T,A,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile186Asn/c.557T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),9464,97,9616,"0,0100873544",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,"0,14",Tolerated,"33,37","16,67"
"low bq, low freq, many artifacts, many samples",UPN2_054,12,12022451,T,A,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile186Asn/c.557T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),7104,76,7220,"0,0105263158",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,"0,14",Tolerated,"33,39","16,36"
"low bq, low freq, many artifacts, many samples",UPN2_008,12,12022451,T,A,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile186Asn/c.557T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),9899,139,10087,"0,013780113",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,"0,14",Tolerated,"32,62","15,81"
"low bq, low freq, many artifacts, many samples",UPN2_009,12,12022451,T,A,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile186Asn/c.557T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),9287,99,9423,"0,0105062082",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,"0,14",Tolerated,"32,93","15,25"
"low bq, low freq, many artifacts, many samples",UPN2_056,12,12022451,T,A,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile186Asn/c.557T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),3713,39,3765,"0,0103585657",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,"0,14",Tolerated,"33,51","18,49"
"low bq, low freq, many artifacts, many samples",UPN2_057,12,12022451,T,A,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile186Asn/c.557T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),7882,91,8010,"0,011360799",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,"0,14",Tolerated,"33,46","16,55"
"low bq, low freq, many artifacts",UPN2_040,12,12022451,T,A,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile186Asn/c.557T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),2973,33,3015,"0,0109452736",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,"0,14",Tolerated,"32,32","17,09"
"low bq, low freq, many artifacts, many samples",UPN2_059,12,12022453,A,C,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr187Pro/c.559A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9143,174,9362,"0,0185857723",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,89,Tolerated,"27,17","15,16"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_060,12,12022453,A,C,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr187Pro/c.559A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8056,132,8232,"0,0160349854",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,89,Tolerated,"26,89","14,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,12,12022453,A,C,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr187Pro/c.559A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9506,145,9707,"0,0149376738",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,89,Tolerated,"26,88","14,14"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,12,12022453,A,C,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr187Pro/c.559A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10612,208,10887,"0,019105355",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,89,Tolerated,"26,8","14,48"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,12,12022453,A,C,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr187Pro/c.559A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9455,162,9679,"0,0167372662",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,89,Tolerated,"26,73","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_064,12,12022453,A,C,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr187Pro/c.559A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11158,212,11444,"0,0185249913",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,89,Tolerated,"27,03","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_065,12,12022453,A,C,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr187Pro/c.559A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7225,140,7399,"0,0189214759",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,89,Tolerated,"27,18","14,51"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_066,12,12022453,A,C,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr187Pro/c.559A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8468,149,8659,"0,0172075297",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,89,Tolerated,"26,89","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_067,12,12022453,A,C,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr187Pro/c.559A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11247,213,11540,"0,018457539",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,89,Tolerated,"27,17","14,67"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_068,12,12022453,A,C,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr187Pro/c.559A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9415,164,9625,"0,017038961",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,89,Tolerated,"26,73","14,72"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_069,12,12022453,A,C,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr187Pro/c.559A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10848,189,11097,"0,0170316302",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,89,Tolerated,"26,74","14,41"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_070,12,12022453,A,C,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr187Pro/c.559A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6510,120,6646,"0,0180559735",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,89,Tolerated,"26,98","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_071,12,12022453,A,C,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr187Pro/c.559A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7750,135,7923,"0,0170390004",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,89,Tolerated,"27,23","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_072,12,12022453,A,C,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr187Pro/c.559A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11402,209,11668,"0,0179122386",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,89,Tolerated,"27,04","14,86"
"low freq, many artifacts, many samples",UPN2_073,12,12022453,A,C,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr187Pro/c.559A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9549,171,9768,"0,0175061425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,89,Tolerated,27,"14,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,12,12022453,A,C,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr187Pro/c.559A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5415,116,5559,"0,0208670624",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,89,Tolerated,"26,93","15,37"
"low bq, low freq, many artifacts, many samples",UPN2_075,12,12022453,A,C,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr187Pro/c.559A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12846,189,13115,"0,0144109798",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,89,Tolerated,"27,17","14,74"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,12,12022453,A,C,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr187Pro/c.559A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9822,173,10063,"0,0171916923",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,89,Tolerated,"26,85","15,3"
"low bq, low freq, many artifacts, many samples",UPN2_077,12,12022453,A,C,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr187Pro/c.559A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10209,196,10477,"0,0187076453",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,89,Tolerated,"27,06","15,01"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,12,12022453,A,C,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr187Pro/c.559A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9781,214,10048,"0,0212977707",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,89,Tolerated,"26,76","14,75"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_079,12,12022453,A,C,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr187Pro/c.559A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5088,103,5219,"0,0197355815",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,89,Tolerated,"26,92","15,03"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,12,12022453,A,C,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr187Pro/c.559A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10323,180,10566,"0,0170357751",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,89,Tolerated,"26,99","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_081,12,12022453,A,C,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr187Pro/c.559A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),14655,256,14990,"0,017078052",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,89,Tolerated,"27,24","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_082,12,12022453,A,C,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr187Pro/c.559A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9044,157,9268,"0,0169400086",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,89,Tolerated,"27,18","15,11"
"low bq, bad alignment, many samples",UPN2_083,12,12022453,A,C,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr187Pro/c.559A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10564,734,11368,"0,0645672062",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,89,Tolerated,"26,2","15,41"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,12,12022453,A,C,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr187Pro/c.559A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11208,213,11497,"0,0185265721",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,89,Tolerated,"26,8","14,66"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_085,12,12022453,A,C,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr187Pro/c.559A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7503,125,7667,"0,016303639",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,89,Tolerated,"26,88","14,62"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,12,12022453,A,C,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr187Pro/c.559A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5866,109,6012,"0,0181304059",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,89,Tolerated,"26,92","14,61"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_087,12,12022453,A,C,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr187Pro/c.559A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11209,190,11481,"0,0165490811",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,89,Tolerated,"26,97","15,23"
"low bq, low freq, many artifacts",UPN2_088,12,12022453,A,C,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr187Pro/c.559A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8887,170,9124,"0,0186321789",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,89,Tolerated,"27,14","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_059,12,12022456,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr188Pro/c.562A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9193,144,9367,"0,0153731184",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,296,Tolerated,"27,19","14,9"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_060,12,12022456,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr188Pro/c.562A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8093,117,8243,"0,0141938615",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,296,Tolerated,"26,97","14,72"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,12,12022456,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr188Pro/c.562A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9477,180,9715,"0,0185280494",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,296,Tolerated,"26,81","14,53"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,12,12022456,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr188Pro/c.562A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10665,184,10900,"0,0168807339",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,296,Tolerated,"26,8","14,97"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,12,12022456,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr188Pro/c.562A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9504,150,9694,"0,0154734888",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,296,Tolerated,"26,88","15,07"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,12,12022456,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr188Pro/c.562A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11214,178,11459,"0,0155336417",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,296,Tolerated,"26,93","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_065,12,12022456,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr188Pro/c.562A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7254,125,7411,"0,0168668196",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,296,Tolerated,"27,15","15,5"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_066,12,12022456,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr188Pro/c.562A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8478,157,8667,"0,0181146879",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,296,Tolerated,"26,92","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_067,12,12022456,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr188Pro/c.562A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11321,175,11559,"0,015139718",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,296,Tolerated,"27,22","15,17"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_068,12,12022456,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr188Pro/c.562A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9401,184,9629,"0,0191089417",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,296,Tolerated,"26,69","14,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_069,12,12022456,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr188Pro/c.562A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10853,209,11113,"0,0188068028",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,296,Tolerated,"26,9","14,75"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_070,12,12022456,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr188Pro/c.562A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6516,111,6656,"0,0166766827",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,296,Tolerated,"26,88","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_071,12,12022456,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr188Pro/c.562A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7742,134,7930,"0,0168978562",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,296,Tolerated,"27,05","15,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,12,12022456,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr188Pro/c.562A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11418,211,11687,"0,0180542483",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,296,Tolerated,"26,99","14,52"
"low freq, many artifacts, many samples",UPN2_073,12,12022456,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr188Pro/c.562A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9579,168,9784,"0,0171708913",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,296,Tolerated,27,"14,29"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,12,12022456,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr188Pro/c.562A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5474,73,5567,"0,0131129872",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,296,Tolerated,"26,81","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_075,12,12022456,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr188Pro/c.562A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12890,194,13127,"0,0147787004",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,296,Tolerated,"27,19","14,84"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,12,12022456,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr188Pro/c.562A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9873,162,10082,"0,0160682404",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,296,Tolerated,"26,74","14,77"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,12,12022456,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr188Pro/c.562A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10269,169,10488,"0,0161136537",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,296,Tolerated,"26,93",15
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,12,12022456,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr188Pro/c.562A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9841,180,10059,"0,0178944229",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,296,Tolerated,"26,91","15,41"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_079,12,12022456,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr188Pro/c.562A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5112,87,5224,"0,0166539051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,296,Tolerated,"26,91","14,53"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,12,12022456,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr188Pro/c.562A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10373,178,10583,"0,0168194274",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,296,Tolerated,"26,94","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_081,12,12022456,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr188Pro/c.562A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),14743,211,15013,"0,0140544861",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,296,Tolerated,"27,25","14,96"
"low freq, many artifacts, many samples",UPN2_082,12,12022456,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr188Pro/c.562A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9086,137,9282,"0,0147597501",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,296,Tolerated,27,"14,52"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,12,12022456,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr188Pro/c.562A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11148,195,11384,"0,0171293043",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,296,Tolerated,"26,65","14,6"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,12,12022456,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr188Pro/c.562A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11243,219,11510,"0,0190269331",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,296,Tolerated,"26,76","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_085,12,12022456,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr188Pro/c.562A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7500,143,7674,"0,0186343498",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,296,Tolerated,"27,04","14,87"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,12,12022456,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr188Pro/c.562A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5894,105,6017,"0,0174505568",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,296,Tolerated,"26,81","14,93"
"low freq, many artifacts, many samples",UPN2_087,12,12022456,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr188Pro/c.562A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11252,193,11496,"0,0167884482",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,296,Tolerated,27,"14,6"
"low bq, bad alignment, low freq, many artifacts",UPN2_088,12,12022456,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr188Pro/c.562A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8943,147,9139,"0,0160849108",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,296,Tolerated,"26,91","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_059,12,12022459,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn189His/c.565A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9197,142,9388,"0,0151256924",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,133,Tolerated,"27,14","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_060,12,12022459,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn189His/c.565A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8089,131,8250,"0,0158787879",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,133,Tolerated,"27,17","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_061,12,12022459,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn189His/c.565A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9523,160,9735,"0,0164355419",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,133,Tolerated,"27,1","14,52"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,12,12022459,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn189His/c.565A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10658,203,10930,"0,0185727356",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,133,Tolerated,"26,81","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_063,12,12022459,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn189His/c.565A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9483,175,9713,"0,0180170905",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,133,Tolerated,"27,06","14,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,12,12022459,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn189His/c.565A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11222,175,11472,"0,0152545328",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,133,Tolerated,"26,99","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_065,12,12022459,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn189His/c.565A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7252,121,7423,"0,0163006871",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,133,Tolerated,"27,26","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_066,12,12022459,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn189His/c.565A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8507,115,8678,"0,0132519014",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,133,Tolerated,"27,05","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_067,12,12022459,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn189His/c.565A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11334,187,11574,"0,0161569034",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,133,Tolerated,"27,3","14,26"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_068,12,12022459,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn189His/c.565A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9413,181,9644,"0,018768146",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,133,Tolerated,"26,8","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_069,12,12022459,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn189His/c.565A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10870,189,11127,"0,0169857104",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,133,Tolerated,"27,01","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_070,12,12022459,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn189His/c.565A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6515,103,6663,"0,0154585022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,133,Tolerated,"27,07","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_071,12,12022459,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn189His/c.565A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7753,133,7943,"0,0167443032",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,133,Tolerated,"27,14","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_072,12,12022459,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn189His/c.565A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11469,179,11702,"0,0152965305",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,133,Tolerated,"27,19","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_073,12,12022459,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn189His/c.565A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9614,140,9799,"0,0142871722",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,133,Tolerated,"27,05","14,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,12,12022459,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn189His/c.565A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5438,99,5573,"0,0177642203",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,133,Tolerated,"26,96","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_075,12,12022459,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn189His/c.565A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12869,205,13155,"0,0155834284",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,133,Tolerated,"27,19","14,34"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,12,12022459,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn189His/c.565A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9861,177,10096,"0,0175316957",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,133,Tolerated,"26,87","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_077,12,12022459,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn189His/c.565A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10267,173,10506,"0,0164667809",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,133,Tolerated,"27,11","14,53"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,12,12022459,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn189His/c.565A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9827,194,10077,"0,0192517614",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,133,Tolerated,"26,84","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_079,12,12022459,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn189His/c.565A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5118,84,5231,"0,0160581151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,133,Tolerated,"27,13","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_080,12,12022459,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn189His/c.565A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10371,179,10606,"0,0168772393",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,133,Tolerated,"27,08","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_081,12,12022459,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn189His/c.565A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),14752,205,15041,"0,0136294129",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,133,Tolerated,"27,23","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_082,12,12022459,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn189His/c.565A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9083,161,9296,"0,0173192771",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,133,Tolerated,"27,16","14,68"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,12,12022459,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn189His/c.565A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11135,206,11417,"0,0180432688",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,133,Tolerated,"26,79","14,88"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,12,12022459,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn189His/c.565A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11290,185,11529,"0,0160464915",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,133,Tolerated,"26,78","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_085,12,12022459,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn189His/c.565A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7508,125,7683,"0,0162696863",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,133,Tolerated,"27,22","14,88"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,12,12022459,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn189His/c.565A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5896,102,6033,"0,0169070114",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,133,Tolerated,"26,92","14,77"
"low freq, many artifacts, many samples",UPN2_087,12,12022459,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn189His/c.565A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11273,173,11525,"0,015010846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,133,Tolerated,27,"14,64"
"low bq, low freq, many artifacts",UPN2_088,12,12022459,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn189His/c.565A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8932,159,9156,"0,0173656619",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,133,Tolerated,"27,16","14,64"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_001,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5558,79,5670,"0,0139329806",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,3","14,33"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_002,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6908,113,7038,"0,0160556976",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"25,89","15,05"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_003,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),1317,20,1341,"0,0149142431",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,27","14,35"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_022,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10795,110,10950,"0,0100456621",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,06","14,06"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_024,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4372,46,4438,"0,0103650293",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,06","15,35"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_026,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11304,129,11493,"0,0112242234",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"25,66","14,71"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_004,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2548,46,2605,"0,0176583493",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"25,87","14,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_089,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9976,191,10200,"0,0187254902",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,84","14,96"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),17697,361,18157,"0,0198821391",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,35","14,74"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_043,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10805,214,11082,"0,0193105938",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,42","14,43"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_044,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5491,115,5619,"0,0204662751",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,31","15,23"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_029,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8743,94,8884,"0,0105808195",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"25,87","15,16"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_005,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),1826,25,1865,"0,0134048257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,3",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11205,238,11516,"0,0206668982",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,27","14,66"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_032,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4045,45,4108,"0,0109542356",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"25,86","14,89"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),16614,355,17064,"0,0208040319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,18","14,79"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_034,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3136,38,3187,"0,011923439",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"25,83",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),18611,348,19057,"0,0182610065",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,31","14,7"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_048,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6109,123,6273,"0,0196078431",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,46",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_006,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8047,119,8195,"0,0145210494",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,25","14,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),13156,289,13517,"0,0213804838",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,43","15,54"
"low bq, bad alignment, many samples",UPN2_050,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),14603,348,15054,"0,0231167796",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,21","14,57"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),15636,336,16089,"0,0208838337",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,39","14,9"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12001,266,12338,"0,02155941",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,31","14,8"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_039,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10515,118,10682,"0,0110466205",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"25,88","14,99"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),17689,370,18165,"0,0203688412",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,25","15,13"
"low bq, bad alignment, many samples",UPN2_054,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),13282,329,13709,"0,0239988329",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,24","14,7"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_007,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),15612,219,15959,"0,0137226643",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,38","14,38"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_008,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),18494,308,18910,"0,0162876785",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"25,95","14,59"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_009,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),17548,252,17886,"0,0140892318",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,31","14,49"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_010,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),14000,202,14249,"0,0141764334",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,29","14,33"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_011,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),14183,182,14438,"0,012605624",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,22","14,87"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),17176,362,17647,"0,0205134017",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,3","14,38"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6961,141,7171,"0,0196625296",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,38","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_090,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6668,117,6813,"0,0171730515",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"27,04","14,6"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),14783,293,15135,"0,0193591014",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,49","14,77"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_058,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),16742,365,17189,"0,0212345104",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,52","14,85"
"low bq, bad alignment, many samples",UPN2_059,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8902,455,9391,"0,0484506442",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"23,89","14,71"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_012,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7263,105,7405,"0,0141796084",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,53","14,47"
"low bq, bad alignment, many samples",UPN2_060,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7797,406,8251,"0,0492061568",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"23,8","14,65"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_013,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4124,57,4190,"0,0136038186",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,4","14,12"
"low bq, low freq, many artifacts, many samples",UPN2_091,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7685,123,7842,"0,0156847743",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"27,03","14,5"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_092,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5039,101,5156,"0,0195888285",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,75","14,38"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_093,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6912,126,7058,"0,0178520827",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,88","14,42"
"low bq, bad alignment, many samples",UPN2_061,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9220,483,9738,"0,0495995071",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"23,81","14,7"
"low bq, bad alignment, many samples",UPN2_062,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10348,539,10933,"0,0493002835",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"23,4","14,79"
"low bq, bad alignment, many samples",UPN2_063,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9215,456,9718,"0,0469232352",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"23,44","14,59"
"low bq, bad alignment, many samples",UPN2_064,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10881,561,11479,"0,0488718529",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"23,54","14,94"
"low bq, bad alignment, many samples",UPN2_065,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7054,338,7427,"0,045509627",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"23,71","14,54"
"low bq, bad alignment, many samples",UPN2_066,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8207,425,8680,"0,0489631336",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"23,83","14,92"
"low bq, bad alignment, many samples",UPN2_067,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11064,474,11574,"0,0409538621",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"23,89","14,49"
"low bq, bad alignment, many samples",UPN2_068,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9104,490,9649,"0,0507824645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"23,44","14,88"
"low bq, bad alignment, many samples",UPN2_069,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10555,516,11132,"0,0463528566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"23,57","14,68"
"low bq, bad alignment, many samples",UPN2_070,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6277,336,6668,"0,050389922",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"23,5","14,77"
"low bq, bad alignment, many samples",UPN2_071,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7514,398,7945,"0,050094399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"23,74","14,86"
"low bq, bad alignment, many samples",UPN2_072,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11115,539,11708,"0,0460368978",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"23,86","14,83"
"low bq, bad alignment, many samples",UPN2_073,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9323,448,9800,"0,0457142857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"23,6","15,07"
"low bq, bad alignment, many samples",UPN2_074,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5298,256,5573,"0,0459357617",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"23,35","14,71"
"low bq, bad alignment, many samples",UPN2_075,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12527,570,13163,"0,0433031984",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"23,8","14,92"
"low bq, bad alignment, many samples",UPN2_076,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9597,454,10100,"0,044950495",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"23,4","14,74"
"low bq, bad alignment, many samples",UPN2_077,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9932,533,10510,"0,0507136061",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"23,48","14,76"
"low bq, bad alignment, many samples",UPN2_078,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9513,511,10080,"0,0506944444",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"23,51","14,81"
"low bq, bad alignment, many samples",UPN2_079,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4966,255,5235,"0,0487106017",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"23,66","15,1"
"low bq, bad alignment, many samples",UPN2_080,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10054,510,10610,"0,0480678605",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"23,64","14,7"
"low bq, bad alignment, many samples",UPN2_081,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),14316,630,15048,"0,0418660287",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"23,85","14,56"
"low bq, bad alignment, many samples",UPN2_082,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8840,432,9301,"0,0464466186",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"23,79","15,09"
"low bq, bad alignment, many samples",UPN2_083,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10758,610,11424,"0,0533963585",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"23,29",15
"low bq, bad alignment, many samples",UPN2_084,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10910,568,11532,"0,049254249",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"23,48","14,76"
"low bq, bad alignment, many samples",UPN2_085,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7289,358,7686,"0,0465781941",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"23,7","14,94"
"low bq, bad alignment, many samples",UPN2_086,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5737,262,6033,"0,0434278137",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"23,52","15,29"
"low bq, bad alignment, many samples",UPN2_087,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10889,589,11529,"0,0510885593",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"23,7","14,74"
"low bq, bad alignment, many samples",UPN2_088,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8706,431,9163,"0,0470369966",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"23,74","14,74"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_094,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9391,178,9608,"0,0185262281",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,73","14,43"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_095,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9766,177,9988,"0,0177212655",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,66","14,53"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_096,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8325,151,8504,"0,01775635",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,89","15,08"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_097,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10381,211,10645,"0,0198215124",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,91","14,23"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_098,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9463,200,9704,"0,0206100577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,91","14,43"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_099,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4951,102,5066,"0,0201342282",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,71","15,4"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_100,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9597,183,9822,"0,0186316432",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,83","14,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_101,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9819,175,10032,"0,0174441786",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,66","14,47"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_102,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9665,201,9903,"0,0202968797",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,82","14,3"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_103,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9744,178,9958,"0,0178750753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,7","14,14"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_104,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10415,191,10657,"0,0179224923",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,68","14,58"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_105,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9598,175,9800,"0,0178571429",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,71","14,12"
"low bq, low freq, many artifacts, many samples",UPN2_106,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11619,233,11886,"0,0196028942",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"27,05","14,26"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_107,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),15674,323,16045,"0,0201308819",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,79","14,27"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_108,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12023,246,12328,"0,019954575",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,85","14,68"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_109,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),13465,247,13762,"0,0179479727",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,79","14,33"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_110,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12584,245,12870,"0,019036519",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,85","14,84"
"low bq, bad alignment, low freq, many artifacts",UPN2_111,12,12022460,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn189Thr/c.566A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),13298,267,13637,"0,0195790863",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,84,Tolerated,"26,78","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_060,12,12022461,T,G,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn189Lys/c.567T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),8122,87,8262,"0,010530138",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,17,Damaging,"28,92","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_061,12,12022461,T,G,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn189Lys/c.567T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),9583,114,9750,"0,0116923077",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,17,Damaging,"28,68","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_062,12,12022461,T,G,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn189Lys/c.567T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),10760,129,10955,"0,011775445",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,17,Damaging,"28,62","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_063,12,12022461,T,G,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn189Lys/c.567T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),9570,103,9731,"0,0105847292",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,17,Damaging,"28,53","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_066,12,12022461,T,G,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn189Lys/c.567T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),8551,90,8694,"0,0103519669",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,17,Damaging,"28,59","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_069,12,12022461,T,G,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn189Lys/c.567T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),10968,113,11146,"0,0101381662",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,17,Damaging,"28,75","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_070,12,12022461,T,G,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn189Lys/c.567T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),6570,79,6681,"0,0118245772",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,17,Damaging,"28,72","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_071,12,12022461,T,G,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn189Lys/c.567T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),7827,80,7952,"0,0100603622",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,17,Damaging,"28,87","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_075,12,12022461,T,G,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn189Lys/c.567T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),12936,146,13177,"0,011079912",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,17,Damaging,"28,97","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_076,12,12022461,T,G,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn189Lys/c.567T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),9970,103,10119,"0,0101788714",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,17,Damaging,"28,53","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_077,12,12022461,T,G,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn189Lys/c.567T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),10343,108,10520,"0,0102661597",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,17,Damaging,"28,7","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_078,12,12022461,T,G,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn189Lys/c.567T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),9923,132,10095,"0,0130757801",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,17,Damaging,"28,64","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_079,12,12022461,T,G,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn189Lys/c.567T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),5144,60,5237,"0,011456941",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,17,Damaging,"28,66","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_080,12,12022461,T,G,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn189Lys/c.567T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),10455,124,10626,"0,0116694899",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,17,Damaging,"28,83","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_082,12,12022461,T,G,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn189Lys/c.567T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),9153,108,9308,"0,0116029222",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,17,Damaging,"28,84","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_084,12,12022461,T,G,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn189Lys/c.567T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),11362,124,11543,"0,0107424413",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,17,Damaging,"28,75","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_085,12,12022461,T,G,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn189Lys/c.567T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),7573,79,7700,"0,0102597403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,17,Damaging,"28,85","15,15"
"low bq, low freq, many artifacts",UPN2_088,12,12022461,T,G,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn189Lys/c.567T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),9029,98,9176,"0,0106800349",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,17,Damaging,"28,86","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_001,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5593,60,5675,"0,0105726872",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"27,8","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_002,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6923,71,7040,"0,0100852273",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"27,39",14
"low bq, low freq, many artifacts, many samples",UPN2_089,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10047,107,10204,"0,0104860839",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"27,48","14,36"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),17754,238,18177,"0,0130934698",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"26,76","14,68"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_043,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10847,143,11090,"0,0128944995",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"26,98","14,97"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_044,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5526,63,5629,"0,0111920412",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"26,67","14,56"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11243,142,11524,"0,0123221104",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"26,85","14,56"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),16669,242,17076,"0,0141719372",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"26,76","15,05"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),18647,235,19073,"0,0123210822",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"26,94","14,73"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_048,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6138,80,6276,"0,0127469726",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"26,88","14,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),13234,175,13534,"0,0129303975",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"26,72","14,73"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),14746,188,15078,"0,0124684971",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"26,77","15,06"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),15756,182,16089,"0,0113120766",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"26,95","14,71"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12080,155,12345,"0,0125556906",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"26,82","15,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),17776,214,18179,"0,0117718246",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"26,68","14,68"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),13400,178,13725,"0,0129690346",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"26,71","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_008,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),18624,209,18929,"0,0110412594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"27,18","14,19"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),17264,223,17668,"0,0126216889",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"26,86","14,53"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7023,96,7175,"0,0133797909",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"26,85","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_090,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6718,74,6819,"0,0108520311",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"27,59","14,8"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),14749,212,15154,"0,0139897057",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"26,9","15,26"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_058,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),16824,211,17201,"0,0122667287",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"26,94","14,58"
"low bq, bad alignment, many samples",UPN2_059,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9074,278,9410,"0,0295430393",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"24,82","15,12"
"low bq, bad alignment, many samples",UPN2_060,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7958,257,8270,"0,031076179",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"24,67","15,07"
"low bq, bad alignment, many samples",UPN2_061,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9360,330,9759,"0,0338149401",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"24,5","14,71"
"low bq, bad alignment, many samples",UPN2_062,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10500,378,10962,"0,0344827586",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"24,46","14,71"
"low bq, bad alignment, many samples",UPN2_063,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9377,295,9742,"0,0302812564",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"24,59","14,53"
"low bq, bad alignment, many samples",UPN2_064,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11067,365,11501,"0,0317363708",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"24,82","14,62"
"low bq, bad alignment, many samples",UPN2_065,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7152,235,7440,"0,0315860215",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"24,93","14,51"
"low bq, bad alignment, many samples",UPN2_066,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8341,295,8701,"0,0339041489",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"24,62","14,6"
"low bq, bad alignment, many samples",UPN2_067,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11170,345,11601,"0,0297388156",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"24,95","14,42"
"low bq, bad alignment, many samples",UPN2_069,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10707,380,11162,"0,0340440781",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"24,66","14,88"
"low bq, bad alignment, many samples",UPN2_070,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6433,221,6690,"0,0330343797",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"24,6","14,98"
"low bq, bad alignment, many samples",UPN2_071,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7647,278,7963,"0,0349114655",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"24,73","14,95"
"low bq, bad alignment, many samples",UPN2_072,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11289,383,11731,"0,0326485381",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"24,89","14,75"
"low bq, bad alignment, many samples",UPN2_073,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9410,343,9812,"0,0349571953",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"24,79","14,66"
"low bq, bad alignment, many samples",UPN2_074,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5349,196,5584,"0,0351002865",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"24,63","14,83"
"low bq, bad alignment, many samples",UPN2_075,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12681,405,13184,"0,0307190534",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"24,92","14,95"
"low bq, bad alignment, many samples",UPN2_076,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9734,341,10130,"0,0336623889",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"24,67","14,74"
"low bq, bad alignment, many samples",UPN2_077,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10102,353,10530,"0,0335232669",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"24,58","14,53"
"low bq, bad alignment, many samples",UPN2_078,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9700,343,10108,"0,033933518",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"24,46","15,18"
"low bq, bad alignment, many samples",UPN2_079,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5016,193,5239,"0,0368390914",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"24,67","15,21"
"low bq, bad alignment, many samples",UPN2_080,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10204,360,10633,"0,0338568607",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"24,68","14,89"
"low bq, bad alignment, many samples",UPN2_081,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),14540,443,15085,"0,0293669208",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"24,8","14,76"
"low bq, bad alignment, many samples",UPN2_082,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8970,285,9316,"0,030592529",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"24,74","14,68"
"low bq, bad alignment, many samples",UPN2_083,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11007,403,11463,"0,0351565908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"24,19","14,75"
"low bq, bad alignment, many samples",UPN2_084,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11114,353,11546,"0,0305733587",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"24,57","14,92"
"low bq, bad alignment, many samples",UPN2_085,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7461,213,7706,"0,0276407994",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"24,81","14,71"
"low bq, bad alignment, many samples",UPN2_086,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5768,230,6040,"0,0380794702",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"24,52","14,8"
"low bq, bad alignment, many samples",UPN2_087,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11079,395,11556,"0,0341813776",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"24,81","14,72"
"low bq, bad alignment, many samples",UPN2_088,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8830,295,9182,"0,0321280767",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"24,83","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_095,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9835,101,9999,"0,0101010101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"27,25","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_096,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8367,98,8511,"0,0115145106",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"27,41","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_097,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10517,111,10654,"0,0104186221",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"27,42","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_099,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4985,57,5068,"0,0112470403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"27,35","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_101,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9872,106,10037,"0,0105609246",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"27,24","14,07"
"low bq, low freq, many artifacts, many samples",UPN2_110,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12687,134,12880,"0,0104037267",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"27,45","14,3"
"low bq, low freq, many artifacts",UPN2_111,12,12022463,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His190Pro/c.569A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),13407,162,13644,"0,0118733509",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,56",Deleterious,145,Tolerated,"27,35","15,22"
"low freq, many artifacts",UPN2_012,12,12022471,T,C,missense_variant(MODERATE|MISSENSE|Tct/Cct|p.Ser193Pro/c.577T>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7305,83,7424,"0,0111799569",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,04",Neutral,"0,033",Damaging,"29,56","31,94"
"low bq, low freq, many artifacts, many samples",UPN2_059,12,12022471,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser193Ala/c.577T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),9199,178,9440,"0,0188559322",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,295,Tolerated,"27,85","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_060,12,12022471,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser193Ala/c.577T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),8109,142,8295,"0,0171187462",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,295,Tolerated,"27,52","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_061,12,12022471,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser193Ala/c.577T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),9546,166,9788,"0,0169595423",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,295,Tolerated,"27,49","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_062,12,12022471,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser193Ala/c.577T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),10695,222,10994,"0,0201928325",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,295,Tolerated,"27,39","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_063,12,12022471,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser193Ala/c.577T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),9500,182,9762,"0,0186437205",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,295,Tolerated,"27,57","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_064,12,12022471,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser193Ala/c.577T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),11246,207,11545,"0,0179298398",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,295,Tolerated,"27,71","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_065,12,12022471,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser193Ala/c.577T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),7253,150,7462,"0,0201018494",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,295,Tolerated,"28,14","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_066,12,12022471,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser193Ala/c.577T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),8536,148,8727,"0,0169588633",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,295,Tolerated,"27,84","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_067,12,12022471,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser193Ala/c.577T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),11334,236,11644,"0,0202679492",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,295,Tolerated,"27,86","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_068,12,12022471,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser193Ala/c.577T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),9463,163,9688,"0,0168249381",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,295,Tolerated,"27,59","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_069,12,12022471,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser193Ala/c.577T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),10906,216,11191,"0,0193012242",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,295,Tolerated,"27,72","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_070,12,12022471,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser193Ala/c.577T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),6533,136,6711,"0,0202652362",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,295,Tolerated,"27,81","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_071,12,12022471,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser193Ala/c.577T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),7805,138,7991,"0,0172694281",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,295,Tolerated,"27,9","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_072,12,12022471,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser193Ala/c.577T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),11487,213,11759,"0,0181137852",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,295,Tolerated,"27,99","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_073,12,12022471,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser193Ala/c.577T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),9570,191,9840,"0,0194105691",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,295,Tolerated,"27,84","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_074,12,12022471,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser193Ala/c.577T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),5463,102,5600,"0,0182142857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,295,Tolerated,"27,6","14,07"
"low bq, low freq, many artifacts, many samples",UPN2_075,12,12022471,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser193Ala/c.577T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),12918,212,13203,"0,0160569568",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,295,Tolerated,"27,91","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_076,12,12022471,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser193Ala/c.577T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),9900,183,10157,"0,018017131",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,295,Tolerated,"27,58","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_077,12,12022471,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser193Ala/c.577T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),10310,192,10561,"0,0181800966",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,295,Tolerated,"27,67","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_078,12,12022471,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser193Ala/c.577T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),9889,182,10131,"0,0179646629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,295,Tolerated,"27,42","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_079,12,12022471,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser193Ala/c.577T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),5112,94,5247,"0,017914999",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,295,Tolerated,"27,87","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_080,12,12022471,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser193Ala/c.577T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),10384,173,10655,"0,0162365087",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,295,Tolerated,"27,66","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_081,12,12022471,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser193Ala/c.577T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),14750,248,15111,"0,0164118854",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,295,Tolerated,"27,92","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_082,12,12022471,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser193Ala/c.577T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),9109,179,9339,"0,0191669344",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,295,Tolerated,"27,74","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_083,12,12022471,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser193Ala/c.577T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),11179,217,11487,"0,0188909202",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,295,Tolerated,"27,53","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_084,12,12022471,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser193Ala/c.577T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),11274,223,11567,"0,0192789833",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,295,Tolerated,"27,68","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_085,12,12022471,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser193Ala/c.577T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),7503,142,7722,"0,0183890184",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,295,Tolerated,"27,78","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_086,12,12022471,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser193Ala/c.577T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),5916,105,6050,"0,0173553719",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,295,Tolerated,"27,87","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_087,12,12022471,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser193Ala/c.577T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),11304,191,11578,"0,0164968043",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,295,Tolerated,"27,93","15,26"
"low bq, low freq, many artifacts",UPN2_088,12,12022471,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser193Ala/c.577T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),8996,157,9203,"0,0170596545",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,48",Neutral,295,Tolerated,"27,78","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_002,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6942,71,7049,"0,0100723507",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"27,11","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_004,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2564,38,2610,"0,014559387",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"27,43",14
"low bq, low freq, many artifacts, many samples",UPN2_089,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10028,120,10195,"0,0117704757",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"27,45","14,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),17768,314,18186,"0,0172660288",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"26,56","14,63"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_043,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10861,170,11116,"0,015293271",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"26,71","14,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_044,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5479,87,5637,"0,0154337414",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"26,51","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_005,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),1836,20,1867,"0,0107123728",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"27,32",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11257,226,11554,"0,0195603254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"26,62","14,72"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),16709,299,17105,"0,0174802689",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"26,51","14,73"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),18686,314,19110,"0,0164311879",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"26,67","14,57"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_048,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6151,102,6304,"0,016180203",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"26,69","14,35"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),13215,195,13549,"0,0143922061",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"26,6","14,62"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),14731,264,15103,"0,0174799709",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"26,73","14,69"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),15786,232,16127,"0,0143858126",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"26,78","14,75"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12043,248,12364,"0,0200582336",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"26,47","14,38"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),17767,310,18208,"0,0170254833",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"26,46","14,72"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),13423,224,13756,"0,0162838034",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"26,46","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_007,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),15658,198,15957,"0,0124083474",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"27,48","15,84"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_008,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),18535,300,18927,"0,0158503725",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"26,54","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_009,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),17587,212,17895,"0,0118468846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"27,25","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_010,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),13987,168,14249,"0,0117903011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"27,26","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_011,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),14171,177,14448,"0,0122508306",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"27,42","14,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),17268,288,17693,"0,0162776239",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"26,64","14,77"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7052,104,7196,"0,0144524736",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"26,62","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_090,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6724,69,6824,"0,0101113716",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"27,57","14,29"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),14822,256,15174,"0,0168709635",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"26,8","14,96"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_058,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),16862,257,17227,"0,014918442",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"26,77","14,28"
"low bq, bad alignment, many samples",UPN2_059,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9002,389,9436,"0,0412250954",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"25,11","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_012,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7242,89,7400,"0,012027027",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"27,57","14,44"
"low bq, bad alignment, many samples",UPN2_060,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7936,314,8297,"0,0378450042",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"25,14","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_013,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4109,51,4189,"0,0121747434",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"27,56","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_092,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5086,58,5162,"0,0112359551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"27,61","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_093,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6966,90,7070,"0,0127298444",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"27,5","14,82"
"low bq, bad alignment, many samples",UPN2_061,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9343,394,9788,"0,0402533715",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"24,88","15,12"
"low bq, bad alignment, many samples",UPN2_062,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10510,433,10994,"0,0393851192",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"24,84","15,22"
"low bq, bad alignment, many samples",UPN2_063,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9360,364,9760,"0,037295082",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"25,02","15,26"
"low bq, bad alignment, many samples",UPN2_064,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11020,461,11539,"0,0399514689",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"25,01","14,93"
"low bq, bad alignment, many samples",UPN2_065,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7087,323,7465,"0,0432685867",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"25,3","14,91"
"low bq, bad alignment, many samples",UPN2_066,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8325,333,8721,"0,0381836945",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"24,96","15,05"
"low bq, bad alignment, many samples",UPN2_067,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11117,444,11637,"0,0381541634",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"25,35","14,97"
"low bq, bad alignment, many samples",UPN2_068,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9218,411,9682,"0,042449907",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"24,96","14,94"
"low bq, bad alignment, many samples",UPN2_069,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10680,454,11189,"0,0405755653",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"25,01","15,16"
"low bq, bad alignment, many samples",UPN2_070,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6411,265,6705,"0,0395227442",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"24,87",15
"low bq, bad alignment, many samples",UPN2_071,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7635,321,7990,"0,040175219",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"25,24","15,17"
"low bq, bad alignment, many samples",UPN2_072,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11187,509,11757,"0,0432933571",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"25,23","15,06"
"low bq, bad alignment, many samples",UPN2_073,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9426,378,9841,"0,0384107306",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"25,08","14,74"
"low bq, bad alignment, many samples",UPN2_074,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5325,231,5598,"0,0412647374",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"24,98","14,9"
"low bq, bad alignment, many samples",UPN2_075,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12680,453,13198,"0,0343233823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"25,27","14,91"
"low bq, bad alignment, many samples",UPN2_076,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9694,426,10158,"0,0419373892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"25,16","14,96"
"low bq, bad alignment, many samples",UPN2_077,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10072,418,10556,"0,0395983327",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"24,91","15,11"
"low bq, bad alignment, many samples",UPN2_078,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9631,460,10125,"0,0454320988",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"24,85","15,05"
"low bq, bad alignment, many samples",UPN2_079,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5023,209,5251,"0,0398019425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"25,09","14,88"
"low bq, bad alignment, many samples",UPN2_080,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10175,430,10658,"0,0403452805",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"24,98","15,25"
"low bq, bad alignment, many samples",UPN2_081,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),14455,579,15110,"0,038318994",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"25,43","15,05"
"low bq, bad alignment, many samples",UPN2_082,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8906,386,9331,"0,0413674847",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"25,24","14,63"
"low bq, bad alignment, many samples",UPN2_083,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10852,536,11488,"0,0466573816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"24,74","14,87"
"low bq, bad alignment, many samples",UPN2_084,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11027,492,11569,"0,042527444",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"24,97","15,09"
"low bq, bad alignment, many samples",UPN2_085,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7406,265,7722,"0,0343175343",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"25,07","14,98"
"low bq, bad alignment, many samples",UPN2_086,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5771,247,6049,"0,0408331956",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"24,9","15,47"
"low bq, bad alignment, many samples",UPN2_087,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11072,447,11583,"0,0385910386",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"25,21","15,3"
"low bq, bad alignment, many samples",UPN2_088,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8851,311,9203,"0,0337933283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"25,24","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_094,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9476,113,9626,"0,0117390401",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"27,53","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_095,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9842,118,10011,"0,0117870343",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"27,31","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_096,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8378,96,8511,"0,0112795206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"27,49","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_097,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10477,128,10658,"0,0120097579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"27,61","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_098,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9555,102,9705,"0,0105100464",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"27,46","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_099,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4985,68,5070,"0,0134122288",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"27,48","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_100,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9683,115,9839,"0,0116881797",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"27,61","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_101,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9885,120,10042,"0,0119498108",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"27,39","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_102,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9737,142,9938,"0,0142885893",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"27,47","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_103,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9820,113,9979,"0,0113237799",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"27,36","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_104,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10503,134,10674,"0,0125538692",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"27,35","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_105,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9664,107,9812,"0,0109050143",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"27,45","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_106,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11729,145,11909,"0,0121756655",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"27,55","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_107,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),15781,199,16074,"0,0123802414",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"27,41","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_108,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12142,141,12332,"0,0114336685",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"27,55","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_109,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),13555,168,13785,"0,01218716",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"27,43","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_110,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12680,156,12887,"0,0121052223",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"27,5","14,42"
"low bq, low freq, many artifacts",UPN2_111,12,12022478,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp195Ala/c.584A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),13407,165,13670,"0,0120702268",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,84,Tolerated,"27,41","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_001,12,12022484,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu197Ala/c.590A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2771,32,2817,"0,0113596024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,58,Tolerated,"28,79","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_042,12,12022484,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu197Ala/c.590A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8885,95,9032,"0,0105181577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,58,Tolerated,"28,72","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_057,12,12022484,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu197Ala/c.590A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7402,76,7531,"0,0100916213",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,58,Tolerated,"28,84","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_059,12,12022484,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu197Ala/c.590A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4592,67,4681,"0,0143131809",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,58,Tolerated,"27,43","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_060,12,12022484,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu197Ala/c.590A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3997,77,4107,"0,0187484782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,58,Tolerated,"27,17","14,97"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,12,12022484,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu197Ala/c.590A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4730,95,4851,"0,019583591",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,58,Tolerated,"26,79","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_062,12,12022484,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu197Ala/c.590A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5339,94,5456,"0,017228739",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,58,Tolerated,"27,04","15,54"
"low bq, low freq, many artifacts, many samples",UPN2_063,12,12022484,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu197Ala/c.590A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4731,80,4842,"0,0165220983",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,58,Tolerated,"27,36","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_064,12,12022484,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu197Ala/c.590A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5595,94,5719,"0,0164364399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,58,Tolerated,"27,45","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_065,12,12022484,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu197Ala/c.590A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3613,65,3698,"0,0175770687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,58,Tolerated,"27,92","14,2"
"low bq, low freq, many artifacts, many samples",UPN2_066,12,12022484,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu197Ala/c.590A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4210,89,4327,"0,0205685232",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,58,Tolerated,"27,23","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_067,12,12022484,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu197Ala/c.590A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5619,94,5751,"0,0163449835",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,58,Tolerated,"27,6","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_068,12,12022484,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu197Ala/c.590A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4701,82,4804,"0,0170691091",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,58,Tolerated,"27,2","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_069,12,12022484,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu197Ala/c.590A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5409,106,5541,"0,0191301209",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,58,Tolerated,"27,5","14,12"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_070,12,12022484,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu197Ala/c.590A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3248,60,3324,"0,0180505415",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,58,Tolerated,"26,98","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_071,12,12022484,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu197Ala/c.590A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3881,62,3960,"0,0156565657",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,58,Tolerated,"27,62","15,39"
"low bq, low freq, many artifacts, many samples",UPN2_072,12,12022484,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu197Ala/c.590A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5697,102,5829,"0,0174987133",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,58,Tolerated,"27,77","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_073,12,12022484,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu197Ala/c.590A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4783,83,4893,"0,0169630084",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,58,Tolerated,"27,31","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_074,12,12022484,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu197Ala/c.590A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2724,43,2781,"0,015462064",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,58,Tolerated,"27,22","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_075,12,12022484,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu197Ala/c.590A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6420,106,6548,"0,0161881491",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,58,Tolerated,"27,31","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_076,12,12022484,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu197Ala/c.590A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4941,79,5043,"0,0156652786",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,58,Tolerated,"27,24","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_077,12,12022484,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu197Ala/c.590A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5121,78,5234,"0,0149025602",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,58,Tolerated,"27,11","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_078,12,12022484,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu197Ala/c.590A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4899,89,5021,"0,0177255527",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,58,Tolerated,"27,13","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_079,12,12022484,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu197Ala/c.590A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2539,57,2609,"0,0218474511",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,58,Tolerated,"27,61","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_080,12,12022484,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu197Ala/c.590A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5172,85,5287,"0,0160771704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,58,Tolerated,"27,55",14
"low bq, low freq, many artifacts, many samples",UPN2_081,12,12022484,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu197Ala/c.590A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7348,95,7487,"0,0126886603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,58,Tolerated,"27,8","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_082,12,12022484,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu197Ala/c.590A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4509,81,4610,"0,0175704989",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,58,Tolerated,"27,44","14,48"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,12,12022484,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu197Ala/c.590A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5567,109,5699,"0,0191261625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,58,Tolerated,"26,84","14,19"
"low bq, low freq, many artifacts, many samples",UPN2_084,12,12022484,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu197Ala/c.590A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5617,88,5732,"0,0153524075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,58,Tolerated,"27,35","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_085,12,12022484,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu197Ala/c.590A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3720,84,3819,"0,0219952867",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,58,Tolerated,"27,66","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_086,12,12022484,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu197Ala/c.590A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2931,49,2999,"0,0163387796",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,58,Tolerated,"27,28","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_087,12,12022484,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu197Ala/c.590A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5621,83,5730,"0,0144851658",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,58,Tolerated,"27,37",14
"low bq, low freq, many artifacts",UPN2_088,12,12022484,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu197Ala/c.590A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4483,65,4570,"0,0142231947",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,58,Tolerated,"27,08","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_059,12,12022487,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln198Pro/c.593A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4604,47,4675,"0,0100534759",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,192,Tolerated,"29,79","14,15"
"low bq, low freq, many artifacts, many samples",UPN2_060,12,12022487,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln198Pro/c.593A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4036,45,4109,"0,0109515697",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,192,Tolerated,"29,35","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_062,12,12022487,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln198Pro/c.593A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5356,56,5458,"0,0102601686",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,192,Tolerated,"29,12","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_064,12,12022487,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln198Pro/c.593A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5617,66,5726,"0,0115263709",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,192,Tolerated,"29,55","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_065,12,12022487,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln198Pro/c.593A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3639,40,3702,"0,0108049703",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,192,Tolerated,"29,9",15
"low bq, low freq, many artifacts, many samples",UPN2_066,12,12022487,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln198Pro/c.593A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4236,61,4329,"0,0140910141",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,192,Tolerated,"29,55","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_067,12,12022487,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln198Pro/c.593A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5662,58,5755,"0,0100781929",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,192,Tolerated,"29,56","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_069,12,12022487,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln198Pro/c.593A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5427,70,5545,"0,0126239856",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,192,Tolerated,"29,63","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_070,12,12022487,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln198Pro/c.593A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3248,50,3324,"0,0150421179",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,192,Tolerated,"29,53","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_076,12,12022487,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln198Pro/c.593A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4940,80,5048,"0,0158478605",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,192,Tolerated,"29,55","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_077,12,12022487,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln198Pro/c.593A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5137,62,5237,"0,011838839",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,192,Tolerated,"29,26","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_078,12,12022487,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln198Pro/c.593A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4948,53,5028,"0,0105409706",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,192,Tolerated,"29,15","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_079,12,12022487,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln198Pro/c.593A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2559,35,2610,"0,0134099617",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,192,Tolerated,"29,53","14,2"
"low bq, low freq, many artifacts, many samples",UPN2_080,12,12022487,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln198Pro/c.593A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5185,61,5290,"0,0115311909",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,192,Tolerated,"29,78",14
"low bq, low freq, many artifacts, many samples",UPN2_082,12,12022487,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln198Pro/c.593A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4520,61,4611,"0,0132292344",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,192,Tolerated,"29,39","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_083,12,12022487,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln198Pro/c.593A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5583,81,5702,"0,0142055419",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,192,Tolerated,"29,09",14
"low bq, low freq, many artifacts, many samples",UPN2_084,12,12022487,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln198Pro/c.593A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5635,58,5737,"0,0101098135",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,192,Tolerated,"29,65","15,4"
"low bq, low freq, many artifacts, many samples",UPN2_085,12,12022487,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln198Pro/c.593A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3747,45,3821,"0,0117770217",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,192,Tolerated,"29,57",14
"low bq, low freq, many artifacts, many samples",UPN2_086,12,12022487,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln198Pro/c.593A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2945,34,3000,"0,0113333333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,192,Tolerated,"29,43","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_087,12,12022487,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln198Pro/c.593A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5625,67,5733,"0,011686726",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,192,Tolerated,"29,58","14,21"
"low bq, low freq, many artifacts",UPN2_088,12,12022487,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln198Pro/c.593A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4475,68,4572,"0,0148731409",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,192,Tolerated,"29,4",14
"low freq, many artifacts",UPN2_008,12,12022495,CT,C,frameshift_variant(HIGH||ctc/|p.Leu201fs/c.602delT|452|ETV6|protein_coding|CODING|ENST00000396373|5|C);LOF=(ETV6|ENSG00000139083|5|0,5071,98,9408,"0,0104166667",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,71",NA
"low freq, many artifacts",UPN2_014,12,12022501,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser203Pro/c.607T>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4443,47,4510,"0,010421286",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,02",Neutral,"0,019",Damaging,"29,17","32,94"
"low freq, many artifacts, many samples",UPN2_050,12,12022501,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser203Pro/c.607T>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7371,83,7524,"0,0110313663",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,02",Neutral,19,Damaging,"25,67","30,51"
"low freq, many artifacts",UPN2_092,12,12022501,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser203Pro/c.607T>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2523,29,2573,"0,01127089",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,02",Neutral,"0,019",Damaging,"27,08","34,38"
"low freq, many artifacts",UPN2_065,12,12022501,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser203Pro/c.607T>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3597,45,3710,"0,0121293801",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,02",Neutral,"0,019",Damaging,"24,89","27,42"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_066,12,12022501,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser203Pro/c.607T>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4233,45,4353,"0,0103376981",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,02",Neutral,19,Damaging,"24,12","26,64"
"low freq, many artifacts",UPN2_072,12,12022501,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser203Pro/c.607T>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5677,64,5849,"0,0109420414",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,02",Neutral,"0,019",Damaging,"24,8","27,64"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_059,12,12022501,T,G,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser203Ala/c.607T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),4578,80,4705,"0,0170031881",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,37,Damaging,"24,65","14,56"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_060,12,12022501,T,G,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser203Ala/c.607T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),4026,67,4134,"0,0162070634",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,37,Damaging,"24,18","14,9"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,12,12022501,T,G,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser203Ala/c.607T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),4734,98,4872,"0,0201149425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,37,Damaging,"23,91","14,7"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,12,12022501,T,G,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser203Ala/c.607T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),5302,110,5472,"0,0201023392",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,37,Damaging,"23,68","15,21"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,12,12022501,T,G,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser203Ala/c.607T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),4713,100,4855,"0,0205973223",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,37,Damaging,"24,36","14,42"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,12,12022501,T,G,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser203Ala/c.607T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),5580,98,5740,"0,0170731707",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,37,Damaging,"24,38","14,83"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_067,12,12022501,T,G,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser203Ala/c.607T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),5620,91,5777,"0,0157521205",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,37,Damaging,"24,72","14,22"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_068,12,12022501,T,G,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser203Ala/c.607T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),4670,91,4814,"0,018903199",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,37,Damaging,"24,21","14,47"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_069,12,12022501,T,G,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser203Ala/c.607T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),5401,104,5557,"0,0187151341",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,37,Damaging,"24,37",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_070,12,12022501,T,G,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser203Ala/c.607T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),3243,55,3335,"0,0164917541",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,37,Damaging,"24,1","14,65"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,12,12022501,T,G,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser203Ala/c.607T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),3845,84,3973,"0,0211427133",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,37,Damaging,"24,87","14,52"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,12,12022501,T,G,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser203Ala/c.607T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),4770,84,4903,"0,0171323679",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,37,Damaging,"24,64","15,26"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,12,12022501,T,G,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser203Ala/c.607T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),2712,55,2787,"0,0197344815",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,37,Damaging,"23,91","14,78"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_075,12,12022501,T,G,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser203Ala/c.607T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),6413,96,6566,"0,0146207737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,37,Damaging,"24,63","14,88"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,12,12022501,T,G,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser203Ala/c.607T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),4920,97,5062,"0,0191623864",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,37,Damaging,"24,25","14,66"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,12,12022501,T,G,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser203Ala/c.607T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),5119,90,5254,"0,0171298059",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,37,Damaging,"24,31","14,97"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,12,12022501,T,G,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser203Ala/c.607T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),4891,101,5043,"0,0200277613",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,37,Damaging,"24,23","14,55"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_079,12,12022501,T,G,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser203Ala/c.607T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),2554,50,2616,"0,0191131498",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,37,Damaging,"24,67","14,26"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,12,12022501,T,G,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser203Ala/c.607T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),5148,97,5303,"0,0182915331",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,37,Damaging,"24,4","14,82"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_081,12,12022501,T,G,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser203Ala/c.607T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),7328,119,7514,"0,0158371041",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,37,Damaging,"25,09","14,24"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_082,12,12022501,T,G,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser203Ala/c.607T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),4509,83,4632,"0,0179188256",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,37,Damaging,"24,34","14,86"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,12,12022501,T,G,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser203Ala/c.607T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),5558,99,5722,"0,0173016428",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,37,Damaging,"23,75","15,24"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,12,12022501,T,G,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser203Ala/c.607T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),5616,80,5760,"0,0138888889",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,37,Damaging,"24,54","15,23"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_085,12,12022501,T,G,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser203Ala/c.607T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),3725,72,3835,"0,0187744459",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,37,Damaging,"24,5","15,06"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,12,12022501,T,G,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser203Ala/c.607T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),2946,41,3006,"0,0136393879",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,37,Damaging,"24,6","14,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_087,12,12022501,T,G,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser203Ala/c.607T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),5571,110,5746,"0,0191437522",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,37,Damaging,"24,62","14,89"
"low bq, bad alignment, low freq, many artifacts",UPN2_088,12,12022501,T,G,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser203Ala/c.607T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),4451,83,4580,"0,0181222707",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,37,Damaging,"24,63","14,24"
"low freq, many artifacts",UPN2_044,12,12022501,T,TC,frameshift_variant(HIGH||ctg/cCtg|p.Leu205fs/c.613dupC|452|ETV6|protein_coding|CODING|ENST00000396373|5|TC|INFO_REALIGN_3_PRIME),2760,45,2802,"0,0160599572",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,84",NA
"low freq, many artifacts",UPN2_039,12,12022501,T,TC,frameshift_variant(HIGH||ctg/cCtg|p.Leu205fs/c.613dupC|452|ETV6|protein_coding|CODING|ENST00000396373|5|TC|INFO_REALIGN_3_PRIME),5259,96,5319,"0,0180485054",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,12",NA
"low freq, many artifacts",UPN2_040,12,12022501,T,TC,frameshift_variant(HIGH||ctg/cCtg|p.Leu205fs/c.613dupC|452|ETV6|protein_coding|CODING|ENST00000396373|5|TC|INFO_REALIGN_3_PRIME),2814,40,2842,"0,0140745954",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,55",NA
"low freq, many artifacts",UPN2_048,12,12022501,TC,T,frameshift_variant(HIGH||ctg/|p.Leu205fs/c.613delC|452|ETV6|protein_coding|CODING|ENST00000396373|5|T|INFO_REALIGN_3_PRIME),3091,32,3138,"0,0101975781",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,38",NA
"low freq, many artifacts",UPN2_093,12,12022501,TC,T,frameshift_variant(HIGH||ctg/|p.Leu205fs/c.613delC|452|ETV6|protein_coding|CODING|ENST00000396373|5|T|INFO_REALIGN_3_PRIME),3485,36,3526,"0,0102098695",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,93",NA
"low freq, many artifacts",UPN2_048,12,12022513,A,G,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn207Asp/c.619A>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),3066,51,3139,"0,0162472125",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,82",Neutral,"0,254",Tolerated,"33,92","35,24"
"low bq, low freq, many artifacts, many samples",UPN2_043,12,12022514,A,T,missense_variant(MODERATE|MISSENSE|aAc/aTc|p.Asn207Ile/c.620A>T|452|ETV6|protein_coding|CODING|ENST00000396373|5|T),5442,58,5527,"0,0104939388",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,59",Neutral,51,Tolerated,"34,26","17,81"
"low bq, low freq, many artifacts, many samples",UPN2_055,12,12022514,A,T,missense_variant(MODERATE|MISSENSE|aAc/aTc|p.Asn207Ile/c.620A>T|452|ETV6|protein_coding|CODING|ENST00000396373|5|T),8696,89,8813,"0,0100987178",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,59",Neutral,51,Tolerated,"34,18","18,67"
"low freq, many artifacts",UPN2_044,12,12022519,A,T,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile209Phe/c.625A>T|452|ETV6|protein_coding|CODING|ENST00000396373|5|T),2757,39,2806,"0,0138987883",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-0,3",Neutral,"0,704",Tolerated,"31,95","30,79"
"low freq, many artifacts",UPN2_044,12,12022528,C,T,missense_variant(MODERATE|MISSENSE|Ctc/Ttc|p.Leu212Phe/c.634C>T|452|ETV6|protein_coding|CODING|ENST00000396373|5|T),2747,51,2806,"0,0181753386",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,88",Neutral,"0,085",Tolerated,"34,64","32,82"
"low freq, many artifacts",UPN2_044,12,12022565,AC,A,frameshift_variant(HIGH||cag/|p.Gln225fs/c.673delC|452|ETV6|protein_coding|CODING|ENST00000396373|5|A|INFO_REALIGN_3_PRIME);LOF=(ETV6|ENSG00000139083|5|0,4939,58,5021,"0,0115514838",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,88",NA
"low bq, low freq, many artifacts, many samples",UPN2_045,12,12022604,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val237Glu/c.710T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),11267,118,11418,"0,0103345595",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,183,Tolerated,"34,55","18,89"
"low bq, low freq, many artifacts",UPN2_053,12,12022604,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val237Glu/c.710T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),11209,120,11377,"0,010547596",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,183,Tolerated,"34,55","18,99"
"low freq, many artifacts",UPN2_068,12,12022606,T,C,missense_variant(MODERATE|MISSENSE|Tct/Cct|p.Ser238Pro/c.712T>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2112,22,2138,"0,0102899906",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,5",Neutral,7,Damaging,"35,11","35,41"
"low bq, low freq, many artifacts, many samples",UPN2_041,12,12022613,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met240Lys/c.719T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),20585,222,20914,"0,0106148991",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,118,Tolerated,"33,66","21,93"
"low bq, low freq, many artifacts, many samples",UPN2_044,12,12022613,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met240Lys/c.719T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),2181,25,2211,"0,0113071009",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,118,Tolerated,"33,7","18,04"
"low bq, low freq, many artifacts, many samples",UPN2_034,12,12022613,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met240Lys/c.719T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),2232,23,2262,"0,0101679929",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,118,Tolerated,"34,21","16,04"
"low bq, low freq, many artifacts",UPN2_058,12,12022613,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met240Lys/c.719T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),8353,94,8478,"0,0110875206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,118,Tolerated,"33,71","23,61"
"low bq, low freq, many artifacts",UPN2_013,12,12022620,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn242Lys/c.726T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),2508,33,2548,"0,0129513344",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,126,Tolerated,"33,95","18,97"
"low bq, low freq, many artifacts, many samples",UPN2_020,12,12022627,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys245Ser/c.733T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),4444,47,4513,"0,0104143585",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,585,Tolerated,"34,4","20,11"
"low bq, low freq, many artifacts, many samples",UPN2_041,12,12022627,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys245Ser/c.733T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),20576,239,20907,"0,0114315779",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,585,Tolerated,"33,92","17,06"
"low bq, low freq, many artifacts, many samples",UPN2_042,12,12022627,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys245Ser/c.733T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),14247,161,14475,"0,0111226252",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,585,Tolerated,"34,05","19,34"
"low bq, low freq, many artifacts, many samples",UPN2_044,12,12022627,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys245Ser/c.733T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),2174,24,2211,"0,0108548168",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,585,Tolerated,"33,99","16,21"
"low bq, low freq, many artifacts, many samples",UPN2_045,12,12022627,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys245Ser/c.733T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),11250,118,11413,"0,010339087",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,585,Tolerated,"33,99","17,08"
"low bq, low freq, many artifacts, many samples",UPN2_032,12,12022627,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys245Ser/c.733T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),2695,32,2738,"0,011687363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,585,Tolerated,"34,4","21,31"
"low bq, low freq, many artifacts, many samples",UPN2_046,12,12022627,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys245Ser/c.733T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),9637,99,9775,"0,0101278772",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,585,Tolerated,"33,96","18,82"
"low bq, low freq, many artifacts, many samples",UPN2_034,12,12022627,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys245Ser/c.733T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),2226,26,2259,"0,0115095175",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,585,Tolerated,"34,39","18,77"
"low bq, low freq, many artifacts, many samples",UPN2_047,12,12022627,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys245Ser/c.733T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),16047,173,16302,"0,0106121948",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,585,Tolerated,"33,96","19,41"
"low bq, low freq, many artifacts, many samples",UPN2_048,12,12022627,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys245Ser/c.733T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),16489,180,16740,"0,0107526882",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,585,Tolerated,"33,91","17,46"
"low bq, low freq, many artifacts, many samples",UPN2_049,12,12022627,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys245Ser/c.733T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),9241,110,9390,"0,01171459",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,585,Tolerated,"33,91","17,92"
"low bq, low freq, many artifacts, many samples",UPN2_051,12,12022627,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys245Ser/c.733T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),9531,101,9676,"0,0104381976",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,585,Tolerated,"33,91","18,08"
"low bq, low freq, many artifacts, many samples",UPN2_052,12,12022627,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys245Ser/c.733T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),8336,101,8473,"0,0119202172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,585,Tolerated,"34,06","17,76"
"low bq, low freq, many artifacts, many samples",UPN2_053,12,12022627,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys245Ser/c.733T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),11198,139,11378,"0,0122165583",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,585,Tolerated,"33,83","18,19"
"low bq, low freq, many artifacts, many samples",UPN2_054,12,12022627,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys245Ser/c.733T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),7443,92,7570,"0,0121532365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,585,Tolerated,"33,92","17,64"
"low bq, low freq, many artifacts, many samples",UPN2_011,12,12022627,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys245Ser/c.733T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),6428,66,6512,"0,0101351351",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,585,Tolerated,34,"17,47"
"low bq, low freq, many artifacts, many samples",UPN2_055,12,12022627,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys245Ser/c.733T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),12853,138,13051,"0,0105739024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,585,Tolerated,"33,95","18,32"
"low bq, low freq, many artifacts, many samples",UPN2_056,12,12022627,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys245Ser/c.733T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),6175,89,6283,"0,0141652077",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,585,Tolerated,"34,01","16,85"
"low bq, low freq, many artifacts, many samples",UPN2_057,12,12022627,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys245Ser/c.733T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),8923,109,9059,"0,0120322331",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,585,Tolerated,"34,05","19,73"
"low bq, low freq, many artifacts, many samples",UPN2_058,12,12022627,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys245Ser/c.733T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),8332,102,8474,"0,0120368185",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,585,Tolerated,"33,96","17,64"
"low bq, low freq, many artifacts",UPN2_012,12,12022627,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys245Ser/c.733T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),4296,44,4353,"0,0101079715",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,585,Tolerated,"34,13","19,36"
"low bq, low freq, many artifacts",UPN2_051,12,12022636,T,A,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser248Thr/c.742T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),9541,97,9675,"0,0100258398",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,55",Neutral,523,Tolerated,"34,09","17,19"
"low bq, bad alignment, many samples",UPN2_001,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5496,671,6184,"0,1085058215",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,307,Tolerated,"23,86","14,77"
"low bq, bad alignment, many samples",UPN2_014,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11339,2853,14244,"0,200294861",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,307,Tolerated,"24,62","15,13"
"low bq, many samples, no database",UPN2_015,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),15228,4106,19416,"0,2114750721",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"24,13","15,17"
"low bq, bad alignment, many samples",UPN2_016,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8200,1939,10164,"0,1907713499",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,307,Tolerated,"24,44","15,22"
"low bq, bad alignment, many samples",UPN2_017,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5444,1521,6998,"0,2173478137",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,307,Tolerated,"24,42","15,26"
"low bq, many samples, no database",UPN2_018,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7841,2057,9929,"0,2071709135",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"24,48","15,09"
"low bq, many samples, no database",UPN2_019,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8757,2442,11241,"0,217240459",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"24,29","15,23"
"low bq, many samples, no database",UPN2_020,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7089,1839,8973,"0,2049481779",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"24,55","15,09"
"low bq, many samples, no database",UPN2_021,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7951,2059,10053,"0,2048144832",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"24,48","15,13"
"low bq, bad alignment, many samples",UPN2_002,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6640,875,7559,"0,1157560524",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,307,Tolerated,"23,04","15,01"
"low bq, bad alignment, many samples",UPN2_003,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),1200,157,1362,"0,1152716593",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,307,Tolerated,"23,07","15,11"
"low bq, many samples, no database",UPN2_022,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11212,2881,14140,"0,203748232",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"24,28","15,15"
"low bq, bad alignment, many samples",UPN2_023,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12195,3198,15466,"0,2067761541",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,307,Tolerated,"24,41","15,21"
"low bq, many samples, no database",UPN2_041,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),35821,5841,41835,"0,1396199355",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,47","14,93"
"low bq, bad alignment, many samples",UPN2_024,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6295,1613,7920,"0,2036616162",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,307,Tolerated,"24,37","15,05"
"low bq, many samples, no database",UPN2_025,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),14127,3535,17730,"0,1993795826",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"24,43","15,09"
"low bq, many samples, no database",UPN2_026,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),13251,3706,17011,"0,2178590324",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"24,34","15,39"
"low bq, bad alignment, many samples",UPN2_004,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),375,44,421,"0,1045130641",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,307,Tolerated,"23,22","14,59"
"low bq, bad alignment, many samples",UPN2_027,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12357,3267,15694,"0,2081687269",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,307,Tolerated,"24,39","15,3"
"low bq, many samples, no database",UPN2_089,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8414,1330,9772,"0,1361031519",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,85","14,63"
"low bq, many samples, no database",UPN2_042,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),24802,3865,28826,"0,1340803441",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,4","14,95"
"low bq, bad alignment, many samples",UPN2_028,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8127,2230,10391,"0,2146087961",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,307,Tolerated,"24,28","15,34"
"low bq, many samples, no database",UPN2_043,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),13619,2158,15863,"0,1360398411",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,39",15
"low bq, many samples, no database",UPN2_044,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3758,659,4431,"0,1487248928",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,25","15,21"
"low bq, many samples, no database",UPN2_029,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12260,3271,15597,"0,2097198179",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"24,26","15,24"
"low bq, many samples, no database",UPN2_030,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12188,3149,15423,"0,2041755819",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"24,43","15,36"
"low bq, bad alignment, many samples",UPN2_031,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8379,2141,10547,"0,2029961126",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,307,Tolerated,"24,47","15,1"
"low bq, bad alignment, many samples",UPN2_005,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),1994,273,2270,"0,1202643172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,307,Tolerated,"23,33","14,78"
"low bq, many samples, no database",UPN2_045,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),19446,3179,22747,"0,1397546929",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,23","14,91"
"low bq, many samples, no database",UPN2_032,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4348,1088,5450,"0,1996330275",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"24,31","15,11"
"low bq, many samples, no database",UPN2_046,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),16474,2928,19528,"0,1499385498",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,34","15,12"
"low bq, many samples, no database",UPN2_033,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9610,2349,12014,"0,1955218911",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"24,57","15,2"
"low bq, many samples, no database",UPN2_034,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3519,971,4513,"0,2151562154",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"24,26","15,13"
"low bq, many samples, no database",UPN2_047,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),27841,4524,32517,"0,1391272258",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,32","14,9"
"low bq, many samples, no database",UPN2_048,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),28475,4760,33369,"0,1426473673",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,53","14,92"
"low bq, many samples, no database",UPN2_035,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12996,3451,16522,"0,2088730178",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"24,31","15,31"
"low bq, many samples, no database",UPN2_036,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9231,2428,11718,"0,2072025943",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"24,22","15,15"
"low bq, many samples, no database",UPN2_006,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6499,833,7359,"0,1131947275",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,28","14,93"
"low bq, many samples, no database",UPN2_049,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),16118,2522,18715,"0,1347582153",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,22","14,88"
"low bq, many samples, no database",UPN2_050,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),18561,2981,21677,"0,1375190294",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,26","14,92"
"low bq, many samples, no database",UPN2_037,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),18091,5046,23209,"0,2174156577",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"24,39","15,17"
"low bq, many samples, no database",UPN2_051,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),16464,2698,19271,"0,1400031135",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,55","15,07"
"low bq, many samples, no database",UPN2_052,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),14324,2441,16847,"0,1448922657",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,3","15,01"
"low bq, many samples, no database",UPN2_038,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),19341,5244,24665,"0,2126089601",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"24,17","15,13"
"low bq, many samples, no database",UPN2_039,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9189,2509,11742,"0,2136773974",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"24,1","15,29"
"low bq, many samples, no database",UPN2_053,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),19288,3248,22632,"0,143513609",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,16","14,86"
"low bq, many samples, no database",UPN2_054,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12843,2159,15082,"0,1431507758",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"22,98","15,06"
"low bq, many samples, no database",UPN2_007,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),13978,1657,15713,"0,1054540826",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,63","14,86"
"low bq, many samples, no database",UPN2_008,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),22314,3001,25408,"0,1181124055",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,42","14,87"
"low bq, many samples, no database",UPN2_009,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),19594,2476,22130,"0,1118843199",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,47",15
"low bq, many samples, no database",UPN2_010,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10563,1434,12034,"0,1191623733",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,23","15,02"
"low bq, many samples, no database",UPN2_011,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11463,1487,13003,"0,114358225",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,64","15,13"
"low bq, many samples, no database",UPN2_055,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),22197,3675,26008,"0,1413026761",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,21","14,87"
"low bq, many samples, no database",UPN2_056,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10687,1774,12518,"0,1417159291",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,35","14,94"
"low bq, many samples, no database",UPN2_090,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7396,1133,8559,"0,1323752775",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,71","14,76"
"low bq, many samples, no database",UPN2_057,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),15349,2542,17970,"0,1414579855",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,27","14,88"
"low bq, many samples, no database",UPN2_058,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),14522,2312,16891,"0,1368776271",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,54","14,82"
"low bq, many samples, no database",UPN2_059,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3320,1192,4520,"0,2637168142",1,0,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"22,92","15,97"
"low bq, bad alignment, many samples",UPN2_012,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7598,979,8594,"0,1139166861",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,307,Tolerated,"23,81",15
"low bq, many samples, no database",UPN2_060,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4764,1694,6476,"0,261581223",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"22,9","16,04"
"low bq, many samples, no database",UPN2_040,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7724,2009,9770,"0,205629478",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"24,21","15,35"
"low bq, bad alignment, many samples",UPN2_013,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4472,579,5078,"0,1140212682",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,307,Tolerated,"23,58","14,86"
"low bq, many samples, no database",UPN2_091,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7433,1120,8583,"0,1304905045",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,67","14,71"
"low bq, bad alignment, many samples",UPN2_092,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3693,579,4292,"0,1349021435",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,307,Tolerated,"23,43","14,53"
"low bq, bad alignment, many samples",UPN2_093,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4373,694,5088,"0,1363993711",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,307,Tolerated,"23,67","14,72"
"low bq, many samples, no database",UPN2_061,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3396,1243,4649,"0,2673693267",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"22,94","16,03"
"low bq, many samples, no database",UPN2_062,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4037,1544,5597,"0,275862069",1,0,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"22,75","16,35"
"low bq, many samples, no database",UPN2_063,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3853,1434,5321,"0,2694982146",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,12","16,08"
"low bq, many samples, no database",UPN2_064,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4203,1532,5759,"0,266018406",1,0,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,05","16,01"
"low bq, many samples, no database",UPN2_065,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2243,828,3081,"0,2687439143",1,0,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"22,95","16,27"
"low bq, many samples, no database",UPN2_066,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),1565,580,2158,"0,2687673772",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"22,79","16,1"
"low bq, many samples, no database",UPN2_067,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),1866,651,2533,"0,257007501",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,15","15,86"
"low bq, many samples, no database",UPN2_068,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3045,1187,4242,"0,2798208392",1,0,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,32","15,97"
"low bq, many samples, no database",UPN2_069,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4793,1727,6535,"0,2642693191",1,0,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"22,92","16,1"
"low bq, many samples, no database",UPN2_070,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2949,1118,4077,"0,2742212411",1,0,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"22,7","16,37"
"low bq, many samples, no database",UPN2_071,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4647,1708,6385,"0,2675019577",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"22,9",16
"low bq, many samples, no database",UPN2_072,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5470,2004,7493,"0,2674496196",1,0,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,33","16,09"
"low bq, many samples, no database",UPN2_073,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4413,1617,6054,"0,2670961348",1,0,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"22,94","16,11"
"low bq, bad alignment, many samples",UPN2_074,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2092,757,2852,"0,26542777",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,307,Tolerated,"22,85","16,05"
"low bq, many samples, no database",UPN2_075,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6958,2339,9320,"0,2509656652",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,05","16,11"
"low bq, many samples, no database",UPN2_076,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4286,1610,5920,"0,2719594595",1,0,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,23,"16,14"
"low bq, many samples, no database",UPN2_077,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3104,1092,4207,"0,2595673877",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,12","15,96"
"low bq, many samples, no database",UPN2_078,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3993,1536,5552,"0,2766570605",1,0,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"22,6","16,13"
"low bq, many samples, no database",UPN2_079,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3133,1229,4378,"0,2807217908",1,0,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"22,96","15,97"
"low bq, many samples, no database",UPN2_080,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4841,1812,6675,"0,2714606742",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,18","15,95"
"low bq, many samples, no database",UPN2_081,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8881,3012,11925,"0,2525786164",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,17","16,06"
"low bq, many samples, no database",UPN2_082,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3602,1286,4905,"0,2621814475",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"22,75","15,91"
"low bq, many samples, no database",UPN2_083,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5186,2001,7202,"0,277839489",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,07","16,08"
"low bq, many samples, no database",UPN2_084,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4689,1690,6407,"0,2637739972",1,0,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"22,95","16,27"
"low bq, many samples, no database",UPN2_085,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2951,1029,3998,"0,2573786893",1,0,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,3","15,86"
"low bq, many samples, no database",UPN2_086,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),1628,651,2283,"0,285151117",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"22,76","15,66"
"low bq, many samples, no database",UPN2_087,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5888,2136,8056,"0,2651439921",1,0,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,09","16,01"
"low bq, many samples, no database",UPN2_088,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2821,946,3777,"0,2504633307",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,06","15,92"
"low bq, many samples, no database",UPN2_094,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10887,1660,12568,"0,1320814768",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,49","14,58"
"low bq, many samples, no database",UPN2_095,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8724,1408,10162,"0,1385554025",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,44","14,53"
"low bq, many samples, no database",UPN2_096,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10529,1596,12154,"0,1313147935",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,54","14,59"
"low bq, bad alignment, many samples",UPN2_097,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10818,1646,12510,"0,1315747402",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,307,Tolerated,"23,78","14,48"
"low bq, many samples, no database",UPN2_098,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8723,1292,10052,"0,1285316355",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,61","14,63"
"low bq, bad alignment, many samples",UPN2_099,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4885,722,5623,"0,1284012093",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,307,Tolerated,"23,43","14,56"
"low bq, bad alignment, many samples",UPN2_100,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8948,1308,10293,"0,127076654",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,307,Tolerated,"23,7","14,53"
"low bq, bad alignment",UPN2_101,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8052,1237,9311,"0,132853614",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,307,Tolerated,"23,49","14,55"
"low bq, many samples, no database",UPN2_102,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8400,1277,9702,"0,1316223459",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,45","14,77"
"low bq, many samples, no database",UPN2_103,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9271,1456,10761,"0,1353034105",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,27","14,64"
"low bq, many samples, no database",UPN2_104,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11328,1684,13048,"0,1290619252",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,27","14,76"
"low bq, many samples, no database",UPN2_105,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9941,1510,11481,"0,1315216445",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,55","14,67"
"low bq, many samples, no database",UPN2_106,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),14755,2199,17007,"0,1292997001",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,68","14,68"
"low bq, many samples, no database",UPN2_107,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),16143,2541,18738,"0,1356067883",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,59","14,58"
"low bq, many samples, no database",UPN2_108,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11485,1686,13214,"0,1275919479",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,68","14,79"
"low bq, many samples, no database",UPN2_109,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12762,2122,14949,"0,1419492943",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,7","14,66"
"low bq, many samples, no database",UPN2_110,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),13839,2117,16016,"0,1321803197",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,72","14,59"
"low bq, many samples, no database",UPN2_111,12,12022649,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His252Pro/c.755A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11127,1803,12971,"0,1390023899",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,307",Tolerated,"23,45","14,72"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_059,12,12022654,A,C,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys254Gln/c.760A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4476,70,4557,"0,0153609831",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,347,Tolerated,"26,99","14,47"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_060,12,12022654,A,C,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys254Gln/c.760A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6455,82,6551,"0,012517173",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,347,Tolerated,"26,87","15,01"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,12,12022654,A,C,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys254Gln/c.760A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4623,62,4697,"0,0131999148",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,347,Tolerated,"26,69","14,35"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,12,12022654,A,C,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys254Gln/c.760A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5546,107,5667,"0,0188812423",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,347,Tolerated,"26,7","14,58"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,12,12022654,A,C,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys254Gln/c.760A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5284,79,5393,"0,0146486186",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,347,Tolerated,"26,87","14,87"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,12,12022654,A,C,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys254Gln/c.760A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5709,84,5812,"0,0144528562",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,347,Tolerated,"26,72","14,43"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_065,12,12022654,A,C,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys254Gln/c.760A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3050,56,3126,"0,0179142674",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,347,Tolerated,"26,97","15,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_066,12,12022654,A,C,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys254Gln/c.760A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2139,32,2177,"0,0146991272",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,347,Tolerated,"26,92",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_068,12,12022654,A,C,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys254Gln/c.760A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4200,77,4296,"0,0179236499",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,347,Tolerated,"26,75","14,51"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_069,12,12022654,A,C,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys254Gln/c.760A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6508,84,6614,"0,0127003326",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,347,Tolerated,"26,9","15,11"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_070,12,12022654,A,C,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys254Gln/c.760A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4026,66,4106,"0,016074038",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,347,Tolerated,"26,68","14,3"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,12,12022654,A,C,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys254Gln/c.760A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6324,105,6460,"0,01625387",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,347,Tolerated,"26,83","14,5"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,12,12022654,A,C,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys254Gln/c.760A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7433,110,7573,"0,0145252872",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,347,Tolerated,"26,86","14,81"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,12,12022654,A,C,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys254Gln/c.760A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6016,77,6110,"0,0126022913",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,347,Tolerated,"26,95","15,01"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,12,12022654,A,C,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys254Gln/c.760A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2839,54,2902,"0,0186078567",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,347,Tolerated,"26,97","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_075,12,12022654,A,C,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys254Gln/c.760A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9241,129,9404,"0,013717567",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,347,Tolerated,"27,03","14,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,12,12022654,A,C,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys254Gln/c.760A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5893,84,6006,"0,013986014",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,347,Tolerated,"26,71","14,61"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,12,12022654,A,C,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys254Gln/c.760A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4181,59,4268,"0,0138238051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,347,Tolerated,"26,9","14,75"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,12,12022654,A,C,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys254Gln/c.760A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5474,98,5612,"0,0174625802",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,347,Tolerated,"26,55","14,42"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_079,12,12022654,A,C,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys254Gln/c.760A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4344,60,4420,"0,0135746606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,347,Tolerated,"26,86","14,22"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,12,12022654,A,C,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys254Gln/c.760A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6657,97,6770,"0,0143279173",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,347,Tolerated,"26,73","14,13"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_081,12,12022654,A,C,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys254Gln/c.760A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11872,165,12092,"0,0136453854",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,347,Tolerated,"26,96","15,16"
"low freq, many artifacts, many samples",UPN2_082,12,12022654,A,C,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys254Gln/c.760A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4863,78,4956,"0,0157384988",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,347,Tolerated,27,"14,78"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,12,12022654,A,C,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys254Gln/c.760A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7121,114,7259,"0,0157046425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,347,Tolerated,"26,62","15,09"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,12,12022654,A,C,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys254Gln/c.760A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6370,107,6519,"0,0164135604",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,347,Tolerated,"26,69","14,19"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_085,12,12022654,A,C,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys254Gln/c.760A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3978,61,4047,"0,0150728935",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,347,Tolerated,"26,97","14,74"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,12,12022654,A,C,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys254Gln/c.760A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2254,36,2299,"0,0156589822",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,347,Tolerated,"26,94","15,25"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_087,12,12022654,A,C,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys254Gln/c.760A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7983,113,8137,"0,013887182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,347,Tolerated,"26,83","14,65"
"low bq, bad alignment, low freq, many artifacts",UPN2_088,12,12022654,A,C,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys254Gln/c.760A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3741,56,3834,"0,0146061555",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,347,Tolerated,"26,93","14,59"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_059,12,12022655,A,C,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys254Thr/c.761A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4449,95,4559,"0,020837903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,244,Tolerated,"25,93","14,62"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_060,12,12022655,A,C,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys254Thr/c.761A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6385,136,6551,"0,0207601893",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,244,Tolerated,"26,25","14,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,12,12022655,A,C,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys254Thr/c.761A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4593,84,4697,"0,0178837556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,244,Tolerated,"25,84","14,55"
"low bq, bad alignment, many samples",UPN2_062,12,12022655,A,C,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys254Thr/c.761A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5517,133,5667,"0,0234692077",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,244,Tolerated,"25,81","15,19"
"low bq, bad alignment, many samples",UPN2_063,12,12022655,A,C,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys254Thr/c.761A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5248,120,5395,"0,0222428174",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,244,Tolerated,"25,95","14,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,12,12022655,A,C,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys254Thr/c.761A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5698,104,5812,"0,0178940124",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,244,Tolerated,"26,2","14,68"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_065,12,12022655,A,C,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys254Thr/c.761A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3056,60,3127,"0,0191877199",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,244,Tolerated,"25,89","14,57"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_066,12,12022655,A,C,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys254Thr/c.761A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2123,44,2177,"0,0202113",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,244,Tolerated,"25,71","14,3"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_067,12,12022655,A,C,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys254Thr/c.761A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2510,53,2570,"0,0206225681",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,244,Tolerated,"26,23","14,89"
"low bq, bad alignment, many samples",UPN2_068,12,12022655,A,C,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys254Thr/c.761A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4181,97,4296,"0,0225791434",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,244,Tolerated,"25,66","14,97"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_069,12,12022655,A,C,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys254Thr/c.761A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6454,128,6614,"0,0193528878",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,244,Tolerated,"26,1","14,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_070,12,12022655,A,C,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys254Thr/c.761A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4010,81,4106,"0,0197272284",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,244,Tolerated,"25,85","14,8"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,12,12022655,A,C,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys254Thr/c.761A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6326,118,6460,"0,0182662539",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,244,Tolerated,"25,8","14,56"
"low bq, bad alignment, many samples",UPN2_072,12,12022655,A,C,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys254Thr/c.761A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7365,178,7573,"0,0235045557",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,244,Tolerated,"25,91","14,56"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,12,12022655,A,C,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys254Thr/c.761A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5952,124,6113,"0,0202846393",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,244,Tolerated,"25,94","14,53"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,12,12022655,A,C,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys254Thr/c.761A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2832,60,2902,"0,0206753963",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,244,Tolerated,"26,3","14,95"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_075,12,12022655,A,C,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys254Thr/c.761A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9190,175,9405,"0,0186071239",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,244,Tolerated,"26,28","14,26"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,12,12022655,A,C,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys254Thr/c.761A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5866,116,6006,"0,0193140193",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,244,Tolerated,"25,77","14,73"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,12,12022655,A,C,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys254Thr/c.761A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4164,93,4270,"0,0217798595",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,244,Tolerated,26,"14,67"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,12,12022655,A,C,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys254Thr/c.761A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5484,110,5612,"0,0196008553",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,244,Tolerated,"25,61","14,6"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_079,12,12022655,A,C,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys254Thr/c.761A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4290,96,4420,"0,021719457",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,244,Tolerated,"25,97","14,61"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,12,12022655,A,C,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys254Thr/c.761A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6599,143,6770,"0,0211225997",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,244,Tolerated,"26,06","14,78"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_081,12,12022655,A,C,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys254Thr/c.761A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11785,243,12094,"0,0200926079",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,244,Tolerated,"26,14","14,89"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_082,12,12022655,A,C,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys254Thr/c.761A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4824,107,4959,"0,0215769308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,244,Tolerated,26,"14,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,12,12022655,A,C,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys254Thr/c.761A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7079,159,7260,"0,0219008264",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,244,Tolerated,"25,71","14,33"
"low bq, bad alignment, many samples",UPN2_084,12,12022655,A,C,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys254Thr/c.761A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6341,156,6523,"0,0239153764",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,244,Tolerated,"25,91","14,53"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_085,12,12022655,A,C,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys254Thr/c.761A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3959,78,4047,"0,019273536",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,244,Tolerated,"26,11","14,6"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,12,12022655,A,C,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys254Thr/c.761A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2262,34,2300,"0,0147826087",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,244,Tolerated,"25,68","14,38"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_087,12,12022655,A,C,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys254Thr/c.761A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7942,162,8138,"0,019906611",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,244,Tolerated,"26,04","14,65"
"low bq, bad alignment, low freq, many artifacts",UPN2_088,12,12022655,A,C,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys254Thr/c.761A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3742,63,3834,"0,0164319249",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,244,Tolerated,"26,54","14,52"
"low bq, low freq, many artifacts",UPN2_066,12,12022660,T,A,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser256Thr/c.766T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),2126,22,2176,"0,0101102941",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,29",Neutral,"0,7",Tolerated,"31,16","19,05"
"low bq, low freq, many artifacts",UPN2_067,12,12022660,T,G,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser256Ala/c.766T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),2524,29,2572,"0,0112752722",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,66",Neutral,329,Tolerated,"31,05",16
"low bq, low freq, many artifacts, many samples",UPN2_059,12,12022663,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser257Arg/c.769A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4493,53,4562,"0,0116177115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,34,Damaging,"27,22","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_060,12,12022663,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser257Arg/c.769A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6455,74,6555,"0,0112890923",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,34,Damaging,"27,35","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_061,12,12022663,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser257Arg/c.769A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4622,70,4707,"0,014871468",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,34,Damaging,"27,47","14,19"
"low bq, low freq, many artifacts, many samples",UPN2_062,12,12022663,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser257Arg/c.769A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5569,92,5673,"0,016217169",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,34,Damaging,"27,2","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_063,12,12022663,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser257Arg/c.769A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5301,77,5407,"0,014240799",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,34,Damaging,"27,48","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_064,12,12022663,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser257Arg/c.769A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5702,78,5814,"0,0134158927",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,34,Damaging,"27,23","14,09"
"low bq, low freq, many artifacts, many samples",UPN2_065,12,12022663,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser257Arg/c.769A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3062,61,3135,"0,0194577352",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,34,Damaging,"27,37","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_066,12,12022663,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser257Arg/c.769A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2132,28,2177,"0,0128617363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,34,Damaging,"27,1","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_067,12,12022663,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser257Arg/c.769A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2535,34,2572,"0,0132192846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,34,Damaging,"27,44","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_068,12,12022663,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser257Arg/c.769A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4241,54,4304,"0,0125464684",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,34,Damaging,"27,16","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_069,12,12022663,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser257Arg/c.769A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6513,89,6627,"0,013429908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,34,Damaging,"27,34","14,15"
"low bq, low freq, many artifacts, many samples",UPN2_070,12,12022663,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser257Arg/c.769A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4041,66,4114,"0,0160427807",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,34,Damaging,"27,19","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_071,12,12022663,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser257Arg/c.769A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6351,103,6475,"0,0159073359",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,34,Damaging,"27,33","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_072,12,12022663,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser257Arg/c.769A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7454,114,7587,"0,0150257019",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,34,Damaging,"27,13","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_073,12,12022663,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser257Arg/c.769A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5995,103,6124,"0,0168190725",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,34,Damaging,"27,31","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_074,12,12022663,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser257Arg/c.769A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2856,47,2903,"0,0161901481",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,34,Damaging,"27,56","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_075,12,12022663,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser257Arg/c.769A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9251,128,9412,"0,01359966",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,34,Damaging,"27,61","15,6"
"low bq, low freq, many artifacts, many samples",UPN2_076,12,12022663,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser257Arg/c.769A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5911,88,6013,"0,0146349576",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,34,Damaging,"27,31","14,08"
"low bq, low freq, many artifacts, many samples",UPN2_077,12,12022663,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser257Arg/c.769A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4181,78,4277,"0,0182370821",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,34,Damaging,"27,32","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_078,12,12022663,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser257Arg/c.769A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5494,83,5623,"0,0147608038",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,34,Damaging,"27,23","14,08"
"low bq, low freq, many artifacts, many samples",UPN2_079,12,12022663,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser257Arg/c.769A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4337,73,4426,"0,0164934478",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,34,Damaging,"27,25","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_080,12,12022663,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser257Arg/c.769A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6644,107,6777,"0,0157886971",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,34,Damaging,"27,13","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_081,12,12022663,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser257Arg/c.769A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11897,181,12116,"0,0149389237",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,34,Damaging,"27,17","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_082,12,12022663,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser257Arg/c.769A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4864,79,4962,"0,0159209996",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,34,Damaging,"27,32","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_083,12,12022663,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser257Arg/c.769A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7135,112,7271,"0,0154036584",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,34,Damaging,"27,21","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_084,12,12022663,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser257Arg/c.769A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6412,100,6535,"0,0153022188",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,34,Damaging,"27,02","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_085,12,12022663,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser257Arg/c.769A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3987,55,4053,"0,0135701949",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,34,Damaging,"27,42","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_086,12,12022663,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser257Arg/c.769A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2247,44,2301,"0,0191221208",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,34,Damaging,"27,19","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_087,12,12022663,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser257Arg/c.769A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8016,115,8154,"0,0141035075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,34,Damaging,"27,29","14,44"
"low bq, low freq, many artifacts",UPN2_088,12,12022663,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser257Arg/c.769A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3769,54,3839,"0,0140661631",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,34,Damaging,"27,57","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_059,12,12022678,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser262Arg/c.784A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4450,91,4556,"0,0199736611",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,79","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_060,12,12022678,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser262Arg/c.784A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6403,117,6549,"0,017865323",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,88","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_061,12,12022678,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser262Arg/c.784A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4591,91,4707,"0,0193329084",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,73","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_062,12,12022678,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser262Arg/c.784A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5548,106,5670,"0,0186948854",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,75","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_063,12,12022678,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser262Arg/c.784A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5288,103,5413,"0,0190282653",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,92","14,73"
"low bq, many samples",UPN2_064,12,12022678,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser262Arg/c.784A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5655,134,5811,"0,0230597143",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,72","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_065,12,12022678,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser262Arg/c.784A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3071,54,3130,"0,0172523962",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,59",14
"low bq, many samples",UPN2_066,12,12022678,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser262Arg/c.784A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2112,49,2177,"0,0225080386",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"29,01",14
"low bq, low freq, many artifacts, many samples",UPN2_067,12,12022678,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser262Arg/c.784A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2516,35,2567,"0,0136345929",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,62",14
"low bq, low freq, many artifacts, many samples",UPN2_068,12,12022678,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser262Arg/c.784A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4225,60,4299,"0,0139567341",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,81","14,77"
"low bq, many samples",UPN2_069,12,12022678,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser262Arg/c.784A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6447,147,6619,"0,0222087929",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,75","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_070,12,12022678,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser262Arg/c.784A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4004,86,4111,"0,0209194843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,81","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_071,12,12022678,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser262Arg/c.784A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6330,133,6477,"0,0205341979",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,71","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_072,12,12022678,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser262Arg/c.784A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7399,148,7582,"0,0195199156",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,78","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_073,12,12022678,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser262Arg/c.784A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5951,127,6119,"0,0207550253",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,82","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_074,12,12022678,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser262Arg/c.784A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2836,56,2903,"0,0192903893",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,55","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_075,12,12022678,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser262Arg/c.784A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9185,169,9408,"0,0179634354",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,87","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_076,12,12022678,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser262Arg/c.784A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5848,124,6008,"0,0206391478",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,74","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_077,12,12022678,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser262Arg/c.784A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4169,84,4270,"0,0196721311",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,78","15,17"
"low bq, low freq, many artifacts, many samples",UPN2_078,12,12022678,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser262Arg/c.784A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5489,106,5622,"0,0188545002",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,61","14,19"
"low bq, low freq, many artifacts, many samples",UPN2_079,12,12022678,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser262Arg/c.784A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4330,77,4423,"0,0174089984",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,72","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_080,12,12022678,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser262Arg/c.784A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6631,121,6774,"0,0178624151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,74","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_081,12,12022678,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser262Arg/c.784A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11849,228,12111,"0,0188258608",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,79","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_082,12,12022678,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser262Arg/c.784A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4828,95,4955,"0,019172553",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,74","14,19"
"low bq, many samples",UPN2_083,12,12022678,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser262Arg/c.784A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7079,161,7265,"0,0221610461",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,79","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_084,12,12022678,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser262Arg/c.784A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6351,139,6530,"0,0212863706",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,86","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_085,12,12022678,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser262Arg/c.784A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3952,85,4049,"0,0209928377",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,64","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_086,12,12022678,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser262Arg/c.784A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2249,46,2299,"0,0200086994",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,67","14,28"
"low bq, many samples",UPN2_087,12,12022678,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser262Arg/c.784A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7940,180,8153,"0,0220777628",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,68","14,21"
"low bq, low freq, many artifacts",UPN2_088,12,12022678,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser262Arg/c.784A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3727,82,3831,"0,0214043331",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,189,Tolerated,"28,78","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_060,12,12022681,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr263Pro/c.787A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6388,88,6547,"0,0134412708",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,201,Tolerated,"30,16","15,42"
"low bq, low freq, many artifacts, many samples",UPN2_062,12,12022681,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr263Pro/c.787A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5559,71,5669,"0,0125242547",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,201,Tolerated,"29,99","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_063,12,12022681,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr263Pro/c.787A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5309,70,5412,"0,0129342203",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,201,Tolerated,"30,07","17,81"
"low bq, low freq, many artifacts, many samples",UPN2_064,12,12022681,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr263Pro/c.787A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5714,62,5808,"0,0106749311",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,201,Tolerated,"29,91","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_065,12,12022681,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr263Pro/c.787A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3070,45,3130,"0,0143769968",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,201,Tolerated,"30,15",14
"low bq, low freq, many artifacts, many samples",UPN2_066,12,12022681,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr263Pro/c.787A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2136,25,2176,"0,0114889706",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,201,Tolerated,"29,87",14
"low bq, low freq, many artifacts, many samples",UPN2_067,12,12022681,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr263Pro/c.787A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2513,31,2561,"0,0121046466",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,201,Tolerated,"30,31","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_068,12,12022681,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr263Pro/c.787A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4223,51,4297,"0,0118687456",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,201,Tolerated,"30,03","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_069,12,12022681,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr263Pro/c.787A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6503,77,6616,"0,0116384522",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,201,Tolerated,"30,05","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_070,12,12022681,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr263Pro/c.787A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4030,54,4110,"0,0131386861",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,201,Tolerated,"29,83","15,17"
"low bq, low freq, many artifacts, many samples",UPN2_072,12,12022681,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr263Pro/c.787A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7456,91,7580,"0,012005277",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,201,Tolerated,"30,11","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_073,12,12022681,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr263Pro/c.787A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6007,75,6118,"0,0122589081",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,201,Tolerated,"30,01","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_074,12,12022681,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr263Pro/c.787A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2853,35,2902,"0,0120606478",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,201,Tolerated,"29,63","15,37"
"low bq, low freq, many artifacts, many samples",UPN2_075,12,12022681,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr263Pro/c.787A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9244,102,9406,"0,010844142",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,201,Tolerated,"30,09","16,25"
"low bq, low freq, many artifacts, many samples",UPN2_076,12,12022681,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr263Pro/c.787A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5910,68,6005,"0,0113238968",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,201,Tolerated,"29,85","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_077,12,12022681,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr263Pro/c.787A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4197,44,4267,"0,0103116944",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,201,Tolerated,"29,99","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_078,12,12022681,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr263Pro/c.787A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5518,77,5622,"0,0136961935",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,201,Tolerated,"29,84","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_079,12,12022681,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr263Pro/c.787A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4357,48,4422,"0,0108548168",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,201,Tolerated,"29,86","16,54"
"low bq, low freq, many artifacts, many samples",UPN2_080,12,12022681,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr263Pro/c.787A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6653,79,6772,"0,0116656822",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,201,Tolerated,"30,02","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_082,12,12022681,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr263Pro/c.787A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4863,70,4953,"0,0141328488",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,201,Tolerated,"30,13","16,73"
"low bq, low freq, many artifacts, many samples",UPN2_084,12,12022681,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr263Pro/c.787A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6403,77,6529,"0,0117935365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,201,Tolerated,"29,99","15,39"
"low bq, low freq, many artifacts, many samples",UPN2_086,12,12022681,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr263Pro/c.787A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2256,31,2298,"0,0134899913",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,201,Tolerated,"29,99","15,58"
"low bq, low freq, many artifacts, many samples",UPN2_087,12,12022681,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr263Pro/c.787A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7979,108,8152,"0,0132482826",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,201,Tolerated,"30,01","15,42"
"low bq, low freq, many artifacts",UPN2_088,12,12022681,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr263Pro/c.787A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3755,56,3831,"0,0146175933",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,201,Tolerated,"30,26","14,93"
"low freq, many artifacts",UPN2_044,12,12022684,C,A,missense_variant(MODERATE|MISSENSE|Cgc/Agc|p.Arg264Ser/c.790C>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),4352,83,4438,"0,0187021181",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,"0,113",Tolerated,"33,84","30,01"
"low bq, low freq, many artifacts, many samples",UPN2_041,12,12022688,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val265Glu/c.794T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),41250,427,41972,"0,010173449",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,69,Tolerated,"30,26","18,69"
"low bq, low freq, many artifacts, many samples",UPN2_042,12,12022688,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val265Glu/c.794T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),28544,311,29062,"0,0107012594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,69,Tolerated,"30,29","18,34"
"low bq, low freq, many artifacts, many samples",UPN2_043,12,12022688,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val265Glu/c.794T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),15667,182,15974,"0,0113935145",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,69,Tolerated,"30,39","17,76"
"low bq, low freq, many artifacts, many samples",UPN2_045,12,12022688,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val265Glu/c.794T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),22505,255,22909,"0,0111309966",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,69,Tolerated,"30,27","20,03"
"low bq, low freq, many artifacts, many samples",UPN2_048,12,12022688,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val265Glu/c.794T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),32940,374,33482,"0,011170181",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,69,Tolerated,"30,24","17,56"
"low bq, low freq, many artifacts, many samples",UPN2_050,12,12022688,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val265Glu/c.794T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),21452,225,21858,"0,010293714",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,69,Tolerated,"30,2","16,59"
"low bq, low freq, many artifacts, many samples",UPN2_051,12,12022688,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val265Glu/c.794T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),19051,205,19413,"0,0105599341",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,69,Tolerated,"30,35","16,83"
"low bq, low freq, many artifacts, many samples",UPN2_054,12,12022688,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val265Glu/c.794T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),14923,164,15196,"0,0107923138",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,69,Tolerated,"30,02","17,05"
"low bq, low freq, many artifacts, many samples",UPN2_055,12,12022688,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val265Glu/c.794T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),25732,275,26183,"0,0105029981",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,69,Tolerated,"30,19","16,27"
"low bq, low freq, many artifacts, many samples",UPN2_056,12,12022688,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val265Glu/c.794T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),12384,154,12621,"0,0122018857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,69,Tolerated,"30,35","18,87"
"low bq, low freq, many artifacts, many samples",UPN2_057,12,12022688,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val265Glu/c.794T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),17851,213,18189,"0,0117103744",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,69,Tolerated,"30,32","20,61"
"low bq, low freq, many artifacts, many samples",UPN2_058,12,12022688,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val265Glu/c.794T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),16687,177,16977,"0,0104258703",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,69,Tolerated,"30,37","18,42"
"low bq, low freq, many artifacts",UPN2_086,12,12022688,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val265Glu/c.794T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),2212,24,2294,"0,010462075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,69,Tolerated,"27,96","16,75"
"low bq, low freq, many artifacts, many samples",UPN2_059,12,12022688,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val265Gly/c.794T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),4423,70,4549,"0,0153879974",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,31,Damaging,"28,31","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_060,12,12022688,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val265Gly/c.794T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),6395,79,6534,"0,012090603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,31,Damaging,"28,19","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_061,12,12022688,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val265Gly/c.794T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),4586,68,4700,"0,0144680851",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,31,Damaging,28,"14,65"
"low bq, low freq, many artifacts, many samples",UPN2_062,12,12022688,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val265Gly/c.794T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),5500,93,5661,"0,0164281929",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,31,Damaging,"27,97","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_063,12,12022688,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val265Gly/c.794T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),5269,86,5401,"0,0159229772",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,31,Damaging,"28,09","17,12"
"low bq, low freq, many artifacts, many samples",UPN2_064,12,12022688,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val265Gly/c.794T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),5665,71,5798,"0,0122456019",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,31,Damaging,"28,17","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_065,12,12022688,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val265Gly/c.794T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),3057,46,3124,"0,0147247119",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,31,Damaging,"28,21","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_066,12,12022688,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val265Gly/c.794T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),2122,29,2176,"0,0133272059",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,31,Damaging,"28,18","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_067,12,12022688,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val265Gly/c.794T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),2504,40,2567,"0,0155823919",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,31,Damaging,"27,8","16,38"
"low bq, low freq, many artifacts, many samples",UPN2_068,12,12022688,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val265Gly/c.794T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),4189,58,4292,"0,0135135135",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,31,Damaging,"27,74","15,66"
"low bq, low freq, many artifacts, many samples",UPN2_069,12,12022688,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val265Gly/c.794T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),6453,87,6610,"0,0131618759",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,31,Damaging,"28,15","15,85"
"low bq, low freq, many artifacts, many samples",UPN2_070,12,12022688,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val265Gly/c.794T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),3975,75,4099,"0,0182971456",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,31,Damaging,"27,67","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_071,12,12022688,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val265Gly/c.794T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),6306,95,6463,"0,0146990562",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,31,Damaging,"28,03","15,56"
"low bq, low freq, many artifacts, many samples",UPN2_072,12,12022688,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val265Gly/c.794T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),7385,106,7567,"0,0140081935",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,31,Damaging,"28,06","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_073,12,12022688,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val265Gly/c.794T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),5957,77,6103,"0,0126167459",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,31,Damaging,"28,22","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_074,12,12022688,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val265Gly/c.794T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),2842,36,2898,"0,0124223602",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,31,Damaging,"28,14","16,06"
"low bq, low freq, many artifacts, many samples",UPN2_075,12,12022688,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val265Gly/c.794T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),9136,131,9389,"0,0139524976",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,31,Damaging,"28,6","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_076,12,12022688,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val265Gly/c.794T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),5832,95,5995,"0,0158465388",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,31,Damaging,"28,09","15,45"
"low bq, low freq, many artifacts, many samples",UPN2_077,12,12022688,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val265Gly/c.794T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),4171,50,4263,"0,0117288295",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,31,Damaging,"28,16","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_078,12,12022688,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val265Gly/c.794T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),5464,88,5611,"0,0156834789",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,31,Damaging,"27,75","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_079,12,12022688,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val265Gly/c.794T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),4314,61,4411,"0,0138290637",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,31,Damaging,"28,11","16,48"
"low bq, low freq, many artifacts, many samples",UPN2_080,12,12022688,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val265Gly/c.794T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),6605,96,6764,"0,0141927853",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,31,Damaging,"27,91","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_081,12,12022688,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val265Gly/c.794T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),11804,143,12086,"0,0118318716",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,31,Damaging,"28,24","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_082,12,12022688,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val265Gly/c.794T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),4837,58,4948,"0,0117219078",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,31,Damaging,"28,24","15,72"
"low bq, low freq, many artifacts, many samples",UPN2_083,12,12022688,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val265Gly/c.794T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),7067,101,7254,"0,0139233526",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,31,Damaging,"27,98","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_084,12,12022688,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val265Gly/c.794T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),6328,105,6515,"0,0161166539",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,31,Damaging,"27,95","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_087,12,12022688,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val265Gly/c.794T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),7928,122,8137,"0,0149932408",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,31,Damaging,"28,07","15,25"
"low bq, low freq, many artifacts",UPN2_088,12,12022688,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val265Gly/c.794T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),3734,51,3828,"0,013322884",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,31,Damaging,"28,48","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_041,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),41207,431,41947,"0,0102748707",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"29,54","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_089,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9708,108,9856,"0,0109577922",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"28,58","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_042,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),28595,292,29037,"0,0100561353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"29,56","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_043,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),15710,177,15968,"0,0110846693",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"29,59","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_044,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4357,50,4425,"0,011299435",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"29,57","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_045,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),22552,246,22900,"0,0107423581",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"29,5","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_046,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),19304,222,19623,"0,0113132549",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"29,52","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_047,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),32163,359,32695,"0,0109802722",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"29,54","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_049,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),18521,204,18825,"0,0108366534",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"29,54","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_050,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),21456,246,21850,"0,0112585812",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"29,51","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_051,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),19085,220,19404,"0,0113378685",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"29,58","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_052,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),16715,191,16989,"0,0112425687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"29,54","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_053,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),22436,260,22815,"0,0113960114",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"29,47","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_054,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),14953,163,15193,"0,010728625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"29,46","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_055,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),25730,292,26169,"0,0111582407",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"29,53","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_056,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12431,153,12618,"0,012125535",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"29,55","15,84"
"low bq, low freq, many artifacts, many samples",UPN2_090,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8499,126,8650,"0,014566474",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"28,48",14
"low bq, low freq, many artifacts, many samples",UPN2_057,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),17905,204,18182,"0,0112198878",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"29,56","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_058,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),16735,178,16974,"0,0104866266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"29,58","14,67"
"low bq, bad alignment, many samples",UPN2_059,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4345,183,4544,"0,0402728873",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"26,74","14,46"
"low bq, bad alignment, many samples",UPN2_060,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6261,239,6527,"0,0366171288",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"26,74","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_091,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8534,119,8687,"0,0136986301",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"28,44",14
"low bq, low freq, many artifacts, many samples",UPN2_092,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4258,60,4334,"0,013844024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"28,42","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_093,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5046,78,5135,"0,0151898734",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"28,43","14,51"
"low bq, bad alignment, many samples",UPN2_061,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4516,170,4695,"0,0362087327",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"26,73","14,3"
"low bq, bad alignment, many samples",UPN2_062,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5409,233,5662,"0,0411515366",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"26,59","14,79"
"low bq, bad alignment, many samples",UPN2_063,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5176,213,5395,"0,0394810009",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"26,78","14,56"
"low bq, bad alignment, many samples",UPN2_064,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5565,192,5791,"0,0331548955",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"26,79","14,17"
"low bq, bad alignment, many samples",UPN2_065,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2984,121,3120,"0,0387820513",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"26,66","14,28"
"low bq, bad alignment, many samples",UPN2_066,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2087,79,2175,"0,0363218391",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"26,39","14,85"
"low bq, bad alignment, many samples",UPN2_067,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2458,100,2566,"0,0389711613",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"26,88","14,41"
"low bq, bad alignment, many samples",UPN2_068,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4083,179,4288,"0,041744403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"26,85","14,85"
"low bq, bad alignment, many samples",UPN2_069,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6344,245,6605,"0,0370931113",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"26,6","14,47"
"low bq, bad alignment, many samples",UPN2_070,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3915,170,4098,"0,0414836506",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"26,7","14,27"
"low bq, bad alignment, many samples",UPN2_071,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6200,234,6458,"0,0362341282",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"26,71","14,41"
"low bq, bad alignment, many samples",UPN2_072,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7266,278,7561,"0,0367676233",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"26,51","14,24"
"low bq, bad alignment, many samples",UPN2_073,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5855,232,6096,"0,0380577428",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"26,72","14,48"
"low bq, bad alignment, many samples",UPN2_074,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2788,103,2895,"0,0355785838",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"26,61","14,34"
"low bq, bad alignment, many samples",UPN2_075,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8976,361,9385,"0,0384656367",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"26,93","14,59"
"low bq, bad alignment, many samples",UPN2_076,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5759,214,5993,"0,0357083264",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"26,62","14,6"
"low bq, bad alignment, many samples",UPN2_077,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4091,149,4260,"0,0349765258",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"26,86","14,23"
"low bq, bad alignment, many samples",UPN2_078,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5361,213,5605,"0,0380017841",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"26,56","14,16"
"low bq, bad alignment, many samples",UPN2_079,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4210,190,4412,"0,0430643699",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"26,59","14,62"
"low bq, bad alignment, many samples",UPN2_080,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6482,247,6757,"0,036554684",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"26,75","14,29"
"low bq, bad alignment, many samples",UPN2_081,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11614,430,12081,"0,03559308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"26,68","14,23"
"low bq, bad alignment, many samples",UPN2_082,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4753,169,4944,"0,0341828479",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"26,66","14,16"
"low bq, bad alignment, many samples",UPN2_083,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6930,278,7251,"0,0383395394",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"26,66","14,38"
"low bq, bad alignment, many samples",UPN2_084,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6234,261,6510,"0,0400921659",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"26,53","14,5"
"low bq, bad alignment, many samples",UPN2_085,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3874,150,4038,"0,0371471025",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"26,9","14,09"
"low bq, bad alignment, many samples",UPN2_086,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2196,82,2292,"0,0357766143",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"26,78","14,24"
"low bq, bad alignment, many samples",UPN2_087,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7796,301,8131,"0,0370188169",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"26,71","14,34"
"low bq, bad alignment, many samples",UPN2_088,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3668,151,3827,"0,0394564933",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"26,85","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_094,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12440,191,12676,"0,0150678447",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"28,53","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_095,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10065,141,10237,"0,0137735665",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"28,47",14
"low bq, low freq, many artifacts, many samples",UPN2_096,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12071,153,12265,"0,012474521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"28,5","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_097,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12377,189,12600,"0,015",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"28,64","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_098,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9991,137,10168,"0,0134736428",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"28,46","14,05"
"low bq, low freq, many artifacts, many samples",UPN2_099,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5569,78,5670,"0,0137566138",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"28,32","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_100,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10237,122,10389,"0,0117431899",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"28,63","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_101,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9233,144,9411,"0,0153012432",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"28,61","14,15"
"low bq, low freq, many artifacts, many samples",UPN2_102,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9605,134,9772,"0,0137126484",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"28,62","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_103,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10620,177,10821,"0,0163570834",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"28,53","14,07"
"low bq, low freq, many artifacts, many samples",UPN2_104,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12942,169,13147,"0,0128546436",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"28,43","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_105,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11355,188,11564,"0,0162573504",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"28,57","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_106,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),16929,201,17181,"0,0116989698",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"28,58","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_107,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),18565,238,18874,"0,0126099396",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"28,47","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_108,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),13114,193,13334,"0,0144742763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"28,64","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_109,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),14818,170,15051,"0,0112949306",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"28,55","14,08"
"low bq, low freq, many artifacts, many samples",UPN2_110,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),15865,228,16154,"0,0141141513",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"28,47","14,35"
"low bq, low freq, many artifacts",UPN2_111,12,12022690,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile266Leu/c.796A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12867,184,13085,"0,0140619029",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,141,Tolerated,"28,51","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_059,12,12022691,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile266Ser/c.797T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),4460,64,4544,"0,014084507",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,367,Tolerated,"27,05","15,3"
"low bq, low freq, many artifacts, many samples",UPN2_060,12,12022691,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile266Ser/c.797T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),6400,96,6526,"0,0147103892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,367,Tolerated,"27,06","15,43"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,12,12022691,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile266Ser/c.797T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),4621,53,4694,"0,0112910098",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,367,Tolerated,"26,68","14,83"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,12,12022691,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile266Ser/c.797T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),5544,87,5659,"0,0153737409",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,367,Tolerated,"26,6","15,64"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,12,12022691,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile266Ser/c.797T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),5292,82,5392,"0,0152077151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,367,Tolerated,"26,85","15,57"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,12,12022691,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile266Ser/c.797T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),5689,80,5789,"0,0138193125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,367,Tolerated,"26,79","14,99"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_065,12,12022691,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile266Ser/c.797T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),3055,50,3120,"0,016025641",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,367,Tolerated,"26,81","15,42"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_066,12,12022691,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile266Ser/c.797T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),2132,28,2175,"0,0128735632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,367,Tolerated,"26,59","14,93"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_067,12,12022691,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile266Ser/c.797T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),2516,36,2563,"0,0140460398",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,367,Tolerated,"26,91","15,44"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_068,12,12022691,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile266Ser/c.797T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),4204,77,4288,"0,0179570896",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,367,Tolerated,"26,56","15,09"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_069,12,12022691,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile266Ser/c.797T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),6466,110,6604,"0,0166565718",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,367,Tolerated,"26,85","15,48"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_070,12,12022691,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile266Ser/c.797T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),4019,71,4098,"0,0173255246",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,367,Tolerated,"26,54","15,06"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,12,12022691,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile266Ser/c.797T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),6316,116,6456,"0,0179677819",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,367,Tolerated,"26,65","14,78"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,12,12022691,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile266Ser/c.797T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),7412,106,7561,"0,0140193096",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,367,Tolerated,"26,69","14,74"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,12,12022691,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile266Ser/c.797T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),5991,80,6095,"0,0131255127",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,367,Tolerated,"26,92","15,2"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,12,12022691,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile266Ser/c.797T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),2834,43,2893,"0,0148634635",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,367,Tolerated,"26,87","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_075,12,12022691,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile266Ser/c.797T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),9219,129,9384,"0,0137468031",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,367,Tolerated,"27,18","15,46"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,12,12022691,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile266Ser/c.797T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),5868,89,5992,"0,0148531375",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,367,Tolerated,"26,84","15,2"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,12,12022691,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile266Ser/c.797T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),4170,62,4258,"0,0145608267",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,367,Tolerated,"26,83","15,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,12,12022691,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile266Ser/c.797T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),5485,94,5604,"0,016773733",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,367,Tolerated,"26,79","15,23"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_079,12,12022691,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile266Ser/c.797T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),4324,68,4412,"0,0154125113",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,367,Tolerated,"26,64","14,5"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,12,12022691,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile266Ser/c.797T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),6609,113,6754,"0,0167308262",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,367,Tolerated,"26,82","14,7"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_081,12,12022691,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile266Ser/c.797T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),11848,179,12080,"0,0148178808",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,367,Tolerated,"26,78","15,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_082,12,12022691,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile266Ser/c.797T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),4844,77,4944,"0,0155744337",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,367,Tolerated,"26,99","15,82"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,12,12022691,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile266Ser/c.797T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),7096,115,7251,"0,0158598814",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,367,Tolerated,"26,76","15,41"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,12,12022691,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile266Ser/c.797T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),6376,103,6507,"0,0158291071",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,367,Tolerated,"26,66","15,34"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_085,12,12022691,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile266Ser/c.797T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),3973,57,4038,"0,014115899",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,367,Tolerated,"26,71","15,68"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,12,12022691,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile266Ser/c.797T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),2244,33,2291,"0,0144041903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,367,Tolerated,"26,59","14,61"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_087,12,12022691,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile266Ser/c.797T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),7976,111,8130,"0,0136531365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,367,Tolerated,"26,73","14,83"
"low bq, low freq, many artifacts",UPN2_088,12,12022691,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile266Ser/c.797T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),3755,60,3827,"0,0156780768",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,367,Tolerated,"27,1","15,17"
"low bq, low freq, many artifacts, many samples",UPN2_059,12,12022694,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln267Pro/c.800A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4437,81,4538,"0,0178492728",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,57",Neutral,62,Tolerated,"29,38","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_060,12,12022694,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln267Pro/c.800A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6401,101,6518,"0,0154955508",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,57",Neutral,62,Tolerated,"29,43","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_061,12,12022694,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln267Pro/c.800A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4600,61,4683,"0,0130258381",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,57",Neutral,62,Tolerated,"29,46","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_062,12,12022694,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln267Pro/c.800A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5528,99,5655,"0,0175066313",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,57",Neutral,62,Tolerated,"29,35","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_063,12,12022694,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln267Pro/c.800A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5270,84,5386,"0,0155959896",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,57",Neutral,62,Tolerated,"29,4","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_064,12,12022694,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln267Pro/c.800A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5667,91,5780,"0,0157439446",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,57",Neutral,62,Tolerated,"29,38","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_065,12,12022694,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln267Pro/c.800A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3065,38,3112,"0,0122107969",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,57",Neutral,62,Tolerated,"29,37","14,18"
"low bq, low freq, many artifacts, many samples",UPN2_066,12,12022694,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln267Pro/c.800A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2131,31,2172,"0,0142725599",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,57",Neutral,62,Tolerated,"29,09","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_067,12,12022694,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln267Pro/c.800A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2517,35,2562,"0,0136612022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,57",Neutral,62,Tolerated,"29,54","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_068,12,12022694,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln267Pro/c.800A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4206,59,4283,"0,0137753911",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,57",Neutral,62,Tolerated,"29,45","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_069,12,12022694,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln267Pro/c.800A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6453,104,6593,"0,0157743061",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,57",Neutral,62,Tolerated,"29,5","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_070,12,12022694,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln267Pro/c.800A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4013,63,4090,"0,015403423",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,57",Neutral,62,Tolerated,"29,51","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_071,12,12022694,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln267Pro/c.800A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6326,99,6446,"0,0153583618",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,57",Neutral,62,Tolerated,"29,63","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_072,12,12022694,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln267Pro/c.800A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7406,114,7551,"0,0150973381",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,57",Neutral,62,Tolerated,"29,4","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_073,12,12022694,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln267Pro/c.800A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5987,79,6084,"0,0129848784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,57",Neutral,62,Tolerated,"29,36","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_074,12,12022694,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln267Pro/c.800A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2851,30,2891,"0,0103770322",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,57",Neutral,62,Tolerated,"29,37",14
"low bq, low freq, many artifacts, many samples",UPN2_075,12,12022694,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln267Pro/c.800A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9215,137,9374,"0,0146148923",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,57",Neutral,62,Tolerated,"29,46","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_076,12,12022694,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln267Pro/c.800A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5887,76,5984,"0,0127005348",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,57",Neutral,62,Tolerated,"29,38","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_077,12,12022694,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln267Pro/c.800A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4185,60,4256,"0,0140977444",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,57",Neutral,62,Tolerated,"29,5","14,12"
"low bq, low freq, many artifacts, many samples",UPN2_078,12,12022694,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln267Pro/c.800A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5494,83,5594,"0,0148373257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,57",Neutral,62,Tolerated,"29,44","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_079,12,12022694,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln267Pro/c.800A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4325,65,4407,"0,0147492625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,57",Neutral,62,Tolerated,"29,28","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_080,12,12022694,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln267Pro/c.800A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6620,100,6744,"0,0148279953",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,57",Neutral,62,Tolerated,"29,44","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_081,12,12022694,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln267Pro/c.800A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11855,169,12066,"0,0140062987",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,57",Neutral,62,Tolerated,"29,43","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_082,12,12022694,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln267Pro/c.800A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4823,69,4936,"0,0139789303",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,57",Neutral,62,Tolerated,"29,46","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_083,12,12022694,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln267Pro/c.800A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7095,113,7244,"0,0155991165",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,57",Neutral,62,Tolerated,"29,5","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_084,12,12022694,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln267Pro/c.800A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6376,105,6500,"0,0161538462",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,57",Neutral,62,Tolerated,"29,24","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_085,12,12022694,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln267Pro/c.800A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3959,51,4032,"0,0126488095",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,57",Neutral,62,Tolerated,"29,55","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_086,12,12022694,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln267Pro/c.800A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2249,31,2289,"0,0135430319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,57",Neutral,62,Tolerated,"29,31",14
"low bq, low freq, many artifacts, many samples",UPN2_087,12,12022694,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln267Pro/c.800A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7971,113,8115,"0,0139248306",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,57",Neutral,62,Tolerated,"29,5","14,56"
"low bq, low freq, many artifacts",UPN2_088,12,12022694,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln267Pro/c.800A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3762,50,3820,"0,0130890052",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,57",Neutral,62,Tolerated,"29,35","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_062,12,12022699,A,C,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met269Leu/c.805A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3030,32,3065,"0,0104404568",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,695,Tolerated,"30,92","16,69"
"low bq, low freq, many artifacts, many samples",UPN2_068,12,12022699,A,C,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met269Leu/c.805A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2259,24,2290,"0,0104803493",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,695,Tolerated,"30,84","15,5"
"low bq, low freq, many artifacts, many samples",UPN2_069,12,12022699,A,C,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met269Leu/c.805A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3488,37,3540,"0,0104519774",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,695,Tolerated,"30,89","17,51"
"low bq, low freq, many artifacts, many samples",UPN2_070,12,12022699,A,C,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met269Leu/c.805A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2173,25,2208,"0,0113224638",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,695,Tolerated,"30,93","14,52"
"low bq, low freq, many artifacts",UPN2_077,12,12022699,A,C,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met269Leu/c.805A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2228,25,2261,"0,0110570544",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,695,Tolerated,"31,28","15,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_059,12,12022700,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met269Arg/c.806T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),2269,31,2312,"0,0134083045",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,4,Damaging,"26,68",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_060,12,12022700,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met269Arg/c.806T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),3268,35,3316,"0,0105548854",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,4,Damaging,"26,38",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,12,12022700,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met269Arg/c.806T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),2342,24,2385,"0,0100628931",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,4,Damaging,"25,93","14,29"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,12,12022700,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met269Arg/c.806T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),2818,45,2876,"0,0156467316",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,4,Damaging,"26,35",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,12,12022700,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met269Arg/c.806T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),2697,36,2747,"0,0131052057",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,4,Damaging,"26,27","14,36"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,12,12022700,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met269Arg/c.806T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),2880,43,2934,"0,0146557601",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,4,Damaging,"26,47","14,58"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_065,12,12022700,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met269Arg/c.806T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),1557,21,1590,"0,0132075472",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,4,Damaging,"26,08","14,86"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_068,12,12022700,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met269Arg/c.806T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),2135,29,2173,"0,0133456052",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,4,Damaging,"25,95","14,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_069,12,12022700,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met269Arg/c.806T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),3312,36,3360,"0,0107142857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,4,Damaging,"26,07","15,22"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_070,12,12022700,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met269Arg/c.806T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),2059,31,2096,"0,0147900763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,4,Damaging,"25,53","15,97"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,12,12022700,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met269Arg/c.806T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),3221,49,3295,"0,0148710167",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,4,Damaging,"26,43","14,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,12,12022700,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met269Arg/c.806T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),3774,57,3854,"0,0147898287",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,4,Damaging,"26,41","14,98"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,12,12022700,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met269Arg/c.806T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),3037,40,3103,"0,0128907509",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,4,Damaging,"26,6","15,93"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,12,12022700,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met269Arg/c.806T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),1450,23,1477,"0,0155721056",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,4,Damaging,"26,17","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_075,12,12022700,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met269Arg/c.806T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),4685,57,4772,"0,0119446773",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,4,Damaging,"27,05","14,74"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,12,12022700,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met269Arg/c.806T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),2987,40,3043,"0,0131449228",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,4,Damaging,"26,17","15,2"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,12,12022700,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met269Arg/c.806T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),2118,24,2158,"0,0111214087",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,4,Damaging,"26,59","14,92"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,12,12022700,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met269Arg/c.806T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),2805,30,2852,"0,0105189341",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,4,Damaging,"26,13","15,73"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_079,12,12022700,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met269Arg/c.806T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),2198,28,2236,"0,0125223614",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,4,Damaging,"26,31","14,46"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,12,12022700,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met269Arg/c.806T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),3370,45,3430,"0,0131195335",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,4,Damaging,"26,32","14,29"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_081,12,12022700,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met269Arg/c.806T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),6053,65,6148,"0,0105725439",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,4,Damaging,"26,29","14,11"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_082,12,12022700,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met269Arg/c.806T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),2472,34,2518,"0,01350278",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,4,Damaging,"26,76","14,38"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,12,12022700,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met269Arg/c.806T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),3629,42,3686,"0,0113944655",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,4,Damaging,"25,84","14,83"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,12,12022700,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met269Arg/c.806T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),3250,50,3325,"0,015037594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,4,Damaging,"26,12","17,64"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_087,12,12022700,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met269Arg/c.806T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),4046,67,4132,"0,016214908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,4,Damaging,"26,37","15,31"
"low bq, bad alignment, low freq, many artifacts",UPN2_088,12,12022700,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met269Arg/c.806T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),1895,34,1944,"0,0174897119",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,14",Neutral,4,Damaging,"26,95",14
"low freq, many artifacts",UPN2_006,12,12022733,AC,A,frameshift_variant(HIGH||cgg/|p.Arg282fs/c.844delC|452|ETV6|protein_coding|CODING|ENST00000396373|5|A|INFO_REALIGN_3_PRIME);LOF=(ETV6|ENSG00000139083|5|0,3686,42,3736,"0,01124197",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,17",NA
"low freq, many artifacts",UPN2_078,12,12022747,G,T,missense_variant(MODERATE|MISSENSE|Gtg/Ttg|p.Val285Leu/c.853G>T|452|ETV6|protein_coding|CODING|ENST00000396373|5|T),2831,39,2882,"0,0135322693",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,1",Neutral,"0,318",Tolerated,"35,1","30,62"
"low freq, many artifacts",UPN2_044,12,12022762,TC,T,frameshift_variant(HIGH||tcc/|p.Arg291fs/c.870delC|452|ETV6|protein_coding|CODING|ENST00000396373|5|T|INFO_REALIGN_3_PRIME);LOF=(ETV6|ENSG00000139083|5|0,3583,45,3635,"0,0123796424",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,31",NA
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,12,12022808,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn305Thr/c.914A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7039,73,7149,"0,0102112184",0,0,0,0,1,0,0,0,1,NO,0,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,77",Deleterious,"0,02",Damaging,"26,9","14,78"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,12,12022808,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn305Thr/c.914A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5776,74,5868,"0,0126107703",0,0,0,0,1,0,0,0,1,NO,0,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,77",Deleterious,"0,02",Damaging,"26,88","14,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_068,12,12022808,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn305Thr/c.914A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6977,85,7090,"0,0119887165",0,0,0,0,1,0,0,0,1,NO,0,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,77",Deleterious,"0,02",Damaging,"26,51","14,76"
"low freq, many artifacts, many samples",UPN2_070,12,12022808,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn305Thr/c.914A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4247,54,4314,"0,0125173853",0,0,0,0,1,0,0,0,1,NO,0,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,77",Deleterious,"0,02",Damaging,27,14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,12,12022808,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn305Thr/c.914A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4047,52,4118,"0,0126274891",0,0,0,0,1,0,0,0,1,NO,0,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,77",Deleterious,"0,02",Damaging,"26,91","14,56"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,12,12022808,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn305Thr/c.914A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5598,65,5687,"0,0114295762",0,0,0,0,1,0,0,0,1,NO,0,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,77",Deleterious,"0,02",Damaging,"26,84","14,31"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,12,12022808,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn305Thr/c.914A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8386,95,8522,"0,0111476179",0,0,0,0,1,0,0,0,1,NO,0,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,77",Deleterious,"0,02",Damaging,"26,79","14,87"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,12,12022808,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn305Thr/c.914A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5834,64,5917,"0,010816292",0,0,0,0,1,0,0,0,1,NO,0,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,77",Deleterious,"0,02",Damaging,"26,98","14,11"
"low bq, low freq, many artifacts, many samples",UPN2_081,12,12022808,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn305Thr/c.914A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7631,80,7764,"0,010303967",0,0,0,0,1,0,0,0,1,NO,0,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,77",Deleterious,"0,02",Damaging,"27,36","14,73"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,12,12022808,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn305Thr/c.914A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7300,98,7422,"0,0132039881",0,0,0,0,1,0,0,0,1,NO,0,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,77",Deleterious,"0,02",Damaging,"26,65","14,5"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,12,12022808,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn305Thr/c.914A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8228,120,8382,"0,0143163923",0,0,0,0,1,0,0,0,1,NO,0,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,77",Deleterious,"0,02",Damaging,"26,62","14,77"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_085,12,12022808,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn305Thr/c.914A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8822,93,8949,"0,0103922226",0,0,0,0,1,0,0,0,1,NO,0,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,77",Deleterious,"0,02",Damaging,"26,94","14,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,12,12022808,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn305Thr/c.914A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6190,65,6275,"0,0103585657",0,0,0,0,1,0,0,0,1,NO,0,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,77",Deleterious,"0,02",Damaging,"26,6","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_087,12,12022808,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn305Thr/c.914A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9599,107,9743,"0,0109822437",0,0,0,0,1,0,0,0,1,NO,0,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,77",Deleterious,"0,02",Damaging,"27,16","14,39"
"low bq, low freq, many artifacts",UPN2_088,12,12022808,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn305Thr/c.914A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6670,69,6768,"0,0101950355",0,0,0,0,1,0,0,0,1,NO,0,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,77",Deleterious,"0,02",Damaging,"27,63","15,88"
"low bq, low freq, many artifacts, many samples",UPN2_001,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6484,76,6581,"0,0115483969",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"28,46","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_014,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9448,125,9633,"0,0129762276",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,96","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_015,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12861,193,13146,"0,0146812719",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,39","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_016,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6395,84,6512,"0,0128992629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"28,34","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_017,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4636,55,4716,"0,0116624258",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,4","15,85"
"low bq, low freq, many artifacts, many samples",UPN2_018,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6788,112,6955,"0,0161035226",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,86","15,61"
"low bq, low freq, many artifacts, many samples",UPN2_019,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7351,122,7531,"0,0161997079",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,4",15
"low bq, low freq, many artifacts, many samples",UPN2_020,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6488,81,6619,"0,0122374981",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,63","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_021,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6961,90,7101,"0,0126742712",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,79","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_002,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8334,133,8504,"0,015639699",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,97","16,05"
"low bq, low freq, many artifacts, many samples",UPN2_003,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),1514,23,1553,"0,0148100451",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,7","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_022,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10020,164,10260,"0,0159844055",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,86","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_023,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11720,197,11986,"0,0164358418",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,79","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_041,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),1271,21,1301,"0,0161414297",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,37","15,86"
"low bq, low freq, many artifacts, many samples",UPN2_024,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5394,75,5513,"0,0136042082",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,9","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_025,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11005,156,11240,"0,0138790036",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,95","15,5"
"low bq, low freq, many artifacts, many samples",UPN2_026,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11667,210,11935,"0,0175953079",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,35","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_027,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12803,229,13149,"0,0174157731",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,53","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_089,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7841,146,8023,"0,0181976817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,81","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_042,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),13708,288,14132,"0,0203792811",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,4","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_028,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8786,156,8991,"0,017350684",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,42","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_043,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9824,196,10099,"0,0194078622",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,42","14,91"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_044,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2632,48,2714,"0,0176860722",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"26,89","15,5"
"low bq, low freq, many artifacts, many samples",UPN2_029,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10948,190,11228,"0,0169219808",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,83","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_030,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10417,163,10636,"0,0153253103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,73","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_031,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7067,118,7240,"0,0162983425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,87","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_005,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),2347,43,2404,"0,0178868552",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"28,1","15,95"
"low bq, low freq, many artifacts, many samples",UPN2_045,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12971,245,13342,"0,018363064",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,07","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_032,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4205,65,4310,"0,0150812065",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,88","15,14"
"low bq, many samples",UPN2_046,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9128,221,9433,"0,0234283897",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,22","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_033,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7763,112,7952,"0,014084507",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"28,17","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_034,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),3030,42,3100,"0,0135483871",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,71","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_047,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),15497,316,15984,"0,0197697698",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,33","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_048,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7519,152,7744,"0,0196280992",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,1","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_035,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),14506,216,14816,"0,0145788337",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,88","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_036,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),13861,224,14185,"0,0157913289",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,92",15
"low bq, low freq, many artifacts, many samples",UPN2_006,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8532,105,8704,"0,0120634191",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"28,22","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_049,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10610,210,10905,"0,0192572215",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,23","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_050,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10070,219,10391,"0,0210759311",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,06","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_037,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),16817,257,17171,"0,0149670957",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,47","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_051,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8094,162,8322,"0,0194664744",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,26","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_052,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7691,174,7934,"0,0219309302",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,13","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_038,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),17329,276,17720,"0,0155756208",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,62","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_039,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12337,210,12641,"0,0166126098",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,42","15,53"
"low bq, bad alignment, many samples",UPN2_053,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),13012,309,13445,"0,0229825214",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"26,95","14,94"
"low bq, bad alignment, many samples",UPN2_054,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7093,167,7336,"0,0227644493",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"26,93","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_007,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),16225,211,16537,"0,0127592671",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"28,64","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_008,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),23551,327,24005,"0,013622162",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"28,17","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_009,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),20861,308,21274,"0,0144777663",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"28,39","15,69"
"low bq, low freq, many artifacts, many samples",UPN2_010,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),14015,212,14297,"0,0148282857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"28,21","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_011,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),18447,231,18796,"0,0122898489",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"28,44","14,55"
"low bq, many samples",UPN2_055,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12858,292,13257,"0,0220260994",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,13","14,41"
"low bq, many samples",UPN2_056,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4863,125,5034,"0,0248311482",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,47","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_090,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7229,147,7422,"0,0198059822",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"28,34","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_057,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12202,261,12625,"0,0206732673",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,25","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_058,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12603,271,12991,"0,0208605958",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,36","15,59"
"low bq, bad alignment, many samples",UPN2_059,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),16778,868,17781,"0,0488161521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"25,66","15,37"
"low bq, low freq, many artifacts, many samples",UPN2_012,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8730,135,8921,"0,0151328326",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"28,43","14,63"
"low bq, bad alignment, many samples",UPN2_060,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10374,581,11048,"0,0525887038",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"25,74","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_040,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9546,152,9780,"0,0155419223",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,8","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_013,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5100,68,5221,"0,0130243248",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"28,37","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_091,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7217,124,7369,"0,0168272493",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"28,21","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_092,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4391,84,4499,"0,0186708157",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,97","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_093,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5155,104,5297,"0,019633755",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"28,33","14,7"
"low bq, many samples, no database",UPN2_061,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),13096,784,13989,"0,0560440346",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,"0,026",Damaging,"25,51","15,69"
"low bq, many samples, no database",UPN2_062,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10717,681,11476,"0,0593412339",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,"0,026",Damaging,"25,46","15,79"
"low bq, bad alignment, many samples",UPN2_063,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10716,545,11350,"0,0480176211",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"25,76","15,12"
"low bq, bad alignment, many samples",UPN2_064,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),14949,752,15850,"0,047444795",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"25,77","15,34"
"low bq, bad alignment, many samples",UPN2_065,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),15595,846,16598,"0,0509699964",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"25,81","15,5"
"low bq, bad alignment, many samples",UPN2_066,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),19494,1040,20699,"0,0502439731",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"25,54","15,56"
"low bq, bad alignment, many samples",UPN2_067,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),20188,1021,21413,"0,0476813151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"25,86","15,45"
"low bq, many samples, no database",UPN2_068,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12995,787,13901,"0,056614632",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,"0,026",Damaging,"25,4","15,53"
"low bq, bad alignment, many samples",UPN2_069,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11935,682,12746,"0,0535069826",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"25,5","15,29"
"low bq, many samples, no database",UPN2_070,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7890,481,8441,"0,0569837697",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,"0,026",Damaging,"25,33","15,94"
"low bq, bad alignment, many samples",UPN2_071,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7569,407,8067,"0,0504524606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"25,71","15,67"
"low bq, bad alignment, many samples",UPN2_072,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10284,528,10899,"0,0484448115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"25,78","15,57"
"low bq, many samples, no database",UPN2_073,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7818,428,8323,"0,0514237655",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,"0,026",Damaging,"25,95",16
"low bq, bad alignment, many samples",UPN2_074,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8771,504,9337,"0,053978794",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"25,55","15,24"
"low bq, bad alignment, many samples",UPN2_075,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11826,601,12539,"0,047930457",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"25,99","15,8"
"low bq, bad alignment, many samples",UPN2_076,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10449,613,11154,"0,0549578627",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"25,38","15,52"
"low bq, bad alignment, many samples",UPN2_077,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),15588,908,16680,"0,0544364508",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"25,48","15,28"
"low bq, bad alignment, many samples",UPN2_078,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11318,698,12115,"0,0576145274",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"25,28","15,41"
"low bq, bad alignment, many samples",UPN2_079,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6079,359,6517,"0,0550866963",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"25,7","15,37"
"low bq, bad alignment, many samples",UPN2_080,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10931,575,11589,"0,0496160152",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"25,53","15,35"
"low bq, bad alignment, many samples",UPN2_081,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),14396,696,15217,"0,045738319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"25,86","15,29"
"low bq, bad alignment, many samples",UPN2_082,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),19713,1033,20957,"0,0492914062",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"25,77","15,59"
"low bq, bad alignment, many samples",UPN2_083,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),13531,807,14448,"0,0558554817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"25,27","15,34"
"low bq, bad alignment, many samples",UPN2_084,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),15335,897,16391,"0,054725154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"25,38","15,3"
"low bq, bad alignment, many samples",UPN2_085,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),16415,961,17534,"0,054807802",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"25,47","15,26"
"low bq, bad alignment, many samples",UPN2_086,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11499,639,12262,"0,0521122166",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"25,37","15,54"
"low bq, bad alignment, many samples",UPN2_087,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),17933,992,19077,"0,0519997903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"25,67","15,43"
"low bq, bad alignment, many samples",UPN2_088,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12484,640,13248,"0,0483091787",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"26,02","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_094,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8952,179,9189,"0,0194798128",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,28,"14,65"
"low bq, low freq, many artifacts, many samples",UPN2_095,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7654,171,7861,"0,0217529576",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,67","15,13"
"low bq, many samples",UPN2_096,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9132,207,9392,"0,0220400341",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"28,02","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_097,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9436,175,9652,"0,0181309573",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"28,13","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_098,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8701,192,8929,"0,0215029679",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,88","15,15"
"low bq, many samples",UPN2_099,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),4233,96,4353,"0,022053756",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,62","15,49"
"low bq, low freq, many artifacts, many samples",UPN2_100,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7228,125,7388,"0,0169193286",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"28,24","14,82"
"low bq, many samples",UPN2_101,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7186,186,7410,"0,0251012146",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,77","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_102,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8406,177,8626,"0,0205193601",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,91","15,15"
"low bq, many samples",UPN2_103,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7015,170,7217,"0,023555494",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,55","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_104,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9047,171,9244,"0,0184984855",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,86","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_105,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8159,158,8356,"0,0189085687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,87","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_106,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11733,219,11997,"0,0182545636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"28,02","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_107,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),14445,293,14792,"0,0198080043",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,88","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_108,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10332,188,10557,"0,0178080894",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"28,27","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_109,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10999,218,11260,"0,0193605684",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,74","14,75"
"low bq, many samples",UPN2_110,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11753,299,12104,"0,0247025777",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,82","15,39"
low bq,UPN2_111,12,12022826,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp311Ala/c.932A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9552,224,9815,"0,0228222109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,26,Damaging,"27,79","14,97"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_059,12,12022841,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn316Thr/c.947A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),17545,228,17940,"0,0127090301",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,262,Tolerated,"25,4","15,2"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_060,12,12022841,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn316Thr/c.947A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10910,130,11175,"0,0116331096",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,262,Tolerated,"25,4","14,88"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,12,12022841,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn316Thr/c.947A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),13802,205,14135,"0,0145030067",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,262,Tolerated,"25,13","14,29"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,12,12022841,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn316Thr/c.947A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11336,140,11581,"0,0120887661",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,262,Tolerated,"25,02","14,63"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,12,12022841,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn316Thr/c.947A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11216,128,11450,"0,0111790393",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,262,Tolerated,"25,33","14,34"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,12,12022841,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn316Thr/c.947A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),15692,173,16010,"0,0108057464",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,262,Tolerated,"25,5","14,52"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_065,12,12022841,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn316Thr/c.947A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),16463,175,16765,"0,0104384134",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,262,Tolerated,"25,56","14,86"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_066,12,12022841,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn316Thr/c.947A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),20447,231,20870,"0,0110685194",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,262,Tolerated,"25,43","14,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_068,12,12022841,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn316Thr/c.947A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),13721,179,14013,"0,0127738529",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,262,Tolerated,"25,08","14,78"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_069,12,12022841,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn316Thr/c.947A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12513,182,12831,"0,0141843972",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,262,Tolerated,"25,23","14,66"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_070,12,12022841,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn316Thr/c.947A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8347,107,8515,"0,0125660599",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,262,Tolerated,"24,97","14,48"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,12,12022841,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn316Thr/c.947A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),7944,108,8122,"0,0132972174",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,262,Tolerated,"25,34","14,62"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,12,12022841,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn316Thr/c.947A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10787,125,11032,"0,0113306744",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,262,Tolerated,"25,45","14,66"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,12,12022841,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn316Thr/c.947A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8227,91,8385,"0,0108527132",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,262,Tolerated,"25,61","15,34"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,12,12022841,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn316Thr/c.947A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9229,107,9433,"0,011343157",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,262,Tolerated,"25,36","14,69"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_075,12,12022841,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn316Thr/c.947A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12411,134,12656,"0,0105878635",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,262,Tolerated,"25,67","14,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,12,12022841,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn316Thr/c.947A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10979,162,11245,"0,0144064028",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,262,Tolerated,25,"14,52"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,12,12022841,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn316Thr/c.947A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),16494,186,16847,"0,0110405413",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,262,Tolerated,"25,24","14,93"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,12,12022841,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn316Thr/c.947A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11919,151,12199,"0,0123780638",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,262,Tolerated,"25,07","14,18"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_079,12,12022841,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn316Thr/c.947A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6389,89,6555,"0,0135774218",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,262,Tolerated,"25,36","14,9"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,12,12022841,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn316Thr/c.947A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11456,144,11702,"0,0123055888",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,262,Tolerated,"25,36","14,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_081,12,12022841,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn316Thr/c.947A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),14959,196,15349,"0,0127695615",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,262,Tolerated,"25,47","14,94"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_082,12,12022841,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn316Thr/c.947A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),20670,231,21112,"0,0109416446",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,262,Tolerated,"25,52","14,81"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,12,12022841,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn316Thr/c.947A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),14317,187,14633,"0,0127793344",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,262,Tolerated,"24,98","14,87"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,12,12022841,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn316Thr/c.947A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),16184,208,16548,"0,0125694948",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,262,Tolerated,"25,09","14,37"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_085,12,12022841,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn316Thr/c.947A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),17308,201,17689,"0,011362994",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,262,Tolerated,"25,23","14,34"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,12,12022841,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn316Thr/c.947A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12091,164,12400,"0,0132258065",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,262,Tolerated,"25,36","14,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_087,12,12022841,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn316Thr/c.947A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),18816,238,19244,"0,0123674912",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,262,Tolerated,"25,24","14,55"
"low bq, bad alignment, low freq, many artifacts",UPN2_088,12,12022841,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn316Thr/c.947A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),13121,140,13364,"0,0104759054",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,262,Tolerated,"25,72","14,52"
"low freq, many artifacts",UPN2_048,12,12022843,C,T,missense_variant(MODERATE|MISSENSE|Cac/Tac|p.His317Tyr/c.949C>T|452|ETV6|protein_coding|CODING|ENST00000396373|5|T),7652,94,7783,"0,012077605",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,"0,148",Tolerated,"32,64","33,52"
"low freq, many artifacts",UPN2_092,12,12022844,A,G,missense_variant(MODERATE|MISSENSE|cAc/cGc|p.His317Arg/c.950A>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),4452,48,4515,"0,0106312292",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,29",Neutral,"0,115",Tolerated,"32,36","33,42"
"low bq, low freq, many artifacts",UPN2_044,12,12022844,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His317Leu/c.950A>T|452|ETV6|protein_coding|CODING|ENST00000396373|5|T),2671,37,2729,"0,0135580799",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,68",Deleterious,"0,018",Damaging,"31,09","25,97"
"low bq, low freq, many artifacts",UPN2_056,12,12022844,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His317Leu/c.950A>T|452|ETV6|protein_coding|CODING|ENST00000396373|5|T),5017,53,5104,"0,0103840125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,68",Deleterious,18,Damaging,"31,24","22,13"
"low bq, low freq, many artifacts",UPN2_045,12,12022846,A,T,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile318Phe/c.952A>T|452|ETV6|protein_coding|CODING|ENST00000396373|5|T),13236,135,13431,"0,0100513737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,48,Damaging,"31,91","21,81"
"low bq, low freq, many artifacts, many samples",UPN2_059,12,12022853,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val320Gly/c.959T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),17623,253,17961,"0,0140860754",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,13,Damaging,"29,41","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_060,12,12022853,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val320Gly/c.959T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),10984,152,11195,"0,01357749",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,13,Damaging,"29,55","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_061,12,12022853,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val320Gly/c.959T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),13841,247,14154,"0,0174508973",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,13,Damaging,"29,44","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_062,12,12022853,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val320Gly/c.959T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),11356,184,11598,"0,0158648043",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,13,Damaging,"29,32","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_063,12,12022853,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val320Gly/c.959T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),11255,157,11468,"0,0136902686",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,13,Damaging,"29,52","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_064,12,12022853,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val320Gly/c.959T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),15713,238,16038,"0,0148397556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,13,Damaging,"29,55","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_065,12,12022853,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val320Gly/c.959T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),16443,269,16804,"0,0160080933",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,13,Damaging,"29,58","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_066,12,12022853,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val320Gly/c.959T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),20467,321,20911,"0,0153507723",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,13,Damaging,"29,42","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_067,12,12022853,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val320Gly/c.959T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),21206,340,21645,"0,0157080157",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,13,Damaging,"29,71","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_068,12,12022853,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val320Gly/c.959T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),13726,255,14040,"0,0181623932",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,13,Damaging,"29,24","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_069,12,12022853,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val320Gly/c.959T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),12591,208,12862,"0,0161716685",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,13,Damaging,"29,24","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_070,12,12022853,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val320Gly/c.959T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),8325,154,8528,"0,0180581614",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,13,Damaging,"29,34","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_071,12,12022853,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val320Gly/c.959T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),7984,115,8146,"0,0141173582",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,13,Damaging,"29,58","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_072,12,12022853,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val320Gly/c.959T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),10834,158,11052,"0,014296055",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,13,Damaging,"29,53","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_073,12,12022853,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val320Gly/c.959T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),8255,112,8403,"0,0133285731",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,13,Damaging,"29,61","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_074,12,12022853,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val320Gly/c.959T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),9257,140,9454,"0,0148085466",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,13,Damaging,"29,51","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_075,12,12022853,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val320Gly/c.959T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),12412,230,12687,"0,0181287933",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,13,Damaging,"29,58","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_076,12,12022853,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val320Gly/c.959T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),11022,168,11261,"0,0149187461",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,13,Damaging,"29,18","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_077,12,12022853,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val320Gly/c.959T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),16506,271,16873,"0,0160611628",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,13,Damaging,"29,41","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_078,12,12022853,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val320Gly/c.959T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),11955,198,12223,"0,0161989692",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,13,Damaging,"29,22","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_079,12,12022853,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val320Gly/c.959T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),6425,112,6563,"0,0170653664",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,13,Damaging,"29,56","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_080,12,12022853,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val320Gly/c.959T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),11465,221,11729,"0,018842186",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,13,Damaging,"29,49","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_081,12,12022853,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val320Gly/c.959T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),15081,224,15377,"0,0145672108",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,13,Damaging,"29,51","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_082,12,12022853,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val320Gly/c.959T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),20783,290,21153,"0,0137096393",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,13,Damaging,"29,56","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_083,12,12022853,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val320Gly/c.959T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),14371,229,14681,"0,0155983925",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,13,Damaging,"29,38","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_084,12,12022853,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val320Gly/c.959T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),16214,261,16572,"0,0157494569",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,13,Damaging,"29,36","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_085,12,12022853,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val320Gly/c.959T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),17376,257,17717,"0,0145058418",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,13,Damaging,"29,47","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_086,12,12022853,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val320Gly/c.959T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),12162,184,12415,"0,0148207813",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,13,Damaging,"29,34","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_087,12,12022853,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val320Gly/c.959T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),18897,302,19279,"0,0156647129",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,13,Damaging,"29,54","14,8"
"low bq, low freq, many artifacts",UPN2_088,12,12022853,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val320Gly/c.959T>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),13131,195,13382,"0,0145718129",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,13,Damaging,"29,61","14,67"
"low freq, many artifacts",UPN2_006,12,12022865,C,T,missense_variant(MODERATE|MISSENSE|cCg/cTg|p.Pro324Leu/c.971C>T|452|ETV6|protein_coding|CODING|ENST00000396373|5|T),8591,131,8741,"0,0149868436",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,98",Neutral,"0,004",Damaging,"32,94","34,22"
"low bq, low freq, many artifacts, many samples",UPN2_059,12,12022874,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu327Ala/c.980A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),17699,205,17985,"0,0113983875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,219,Tolerated,"30,18","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_060,12,12022874,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu327Ala/c.980A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11049,130,11205,"0,0116019634",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,219,Tolerated,"30,25","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_061,12,12022874,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu327Ala/c.980A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),13912,194,14167,"0,0136937954",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,219,Tolerated,"30,08","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_062,12,12022874,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu327Ala/c.980A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11422,153,11604,"0,0131851086",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,219,Tolerated,"29,94","15,59"
"low bq, low freq, many artifacts, many samples",UPN2_063,12,12022874,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu327Ala/c.980A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11301,140,11475,"0,0122004357",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,219,Tolerated,"30,13","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_064,12,12022874,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu327Ala/c.980A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),15775,206,16051,"0,0128340913",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,219,Tolerated,"30,12","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_065,12,12022874,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu327Ala/c.980A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),16539,225,16820,"0,0133769322",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,219,Tolerated,"30,07","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_066,12,12022874,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu327Ala/c.980A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),20567,270,20924,"0,0129038425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,219,Tolerated,"30,06","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_067,12,12022874,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu327Ala/c.980A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),21324,249,21667,"0,0114921309",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,219,Tolerated,"30,12","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_068,12,12022874,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu327Ala/c.980A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),13811,167,14053,"0,0118835836",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,219,Tolerated,"29,92","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_069,12,12022874,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu327Ala/c.980A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12613,202,12868,"0,0156978551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,219,Tolerated,"30,08","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_070,12,12022874,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu327Ala/c.980A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8365,120,8535,"0,014059754",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,219,Tolerated,"29,99","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_071,12,12022874,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu327Ala/c.980A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8019,105,8155,"0,0128755365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,219,Tolerated,"30,07","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_072,12,12022874,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu327Ala/c.980A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),10842,145,11062,"0,0131079371",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,219,Tolerated,"30,08","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_073,12,12022874,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu327Ala/c.980A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8264,107,8406,"0,0127290031",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,219,Tolerated,"30,14","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_074,12,12022874,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu327Ala/c.980A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9322,104,9459,"0,0109948197",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,219,Tolerated,"30,16","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_075,12,12022874,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu327Ala/c.980A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12501,139,12695,"0,0109491926",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,219,Tolerated,"30,12","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_076,12,12022874,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu327Ala/c.980A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11077,150,11264,"0,0133167614",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,219,Tolerated,"29,98","16,03"
"low bq, low freq, many artifacts, many samples",UPN2_077,12,12022874,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu327Ala/c.980A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),16576,218,16888,"0,0129085741",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,219,Tolerated,"30,09","15,87"
"low bq, low freq, many artifacts, many samples",UPN2_078,12,12022874,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu327Ala/c.980A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12029,148,12231,"0,0121004006",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,219,Tolerated,"29,99","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_079,12,12022874,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu327Ala/c.980A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6475,76,6573,"0,0115624525",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,219,Tolerated,"30,14","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_080,12,12022874,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu327Ala/c.980A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11541,149,11735,"0,0126970601",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,219,Tolerated,"30,02","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_081,12,12022874,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu327Ala/c.980A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),15131,182,15394,"0,0118227881",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,219,Tolerated,"30,13","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_082,12,12022874,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu327Ala/c.980A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),20825,272,21162,"0,0128532275",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,219,Tolerated,"30,11","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_083,12,12022874,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu327Ala/c.980A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),14415,221,14704,"0,0150299238",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,219,Tolerated,"29,87","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_084,12,12022874,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu327Ala/c.980A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),16262,245,16591,"0,0147670424",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,219,Tolerated,"30,02","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_085,12,12022874,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu327Ala/c.980A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),17423,227,17732,"0,0128017144",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,219,Tolerated,"30,01","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_086,12,12022874,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu327Ala/c.980A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12194,177,12427,"0,0142431802",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,219,Tolerated,"30,01","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_087,12,12022874,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu327Ala/c.980A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),18925,260,19288,"0,0134798839",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,219,Tolerated,"30,15","14,51"
"low bq, low freq, many artifacts",UPN2_088,12,12022874,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu327Ala/c.980A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),13160,184,13391,"0,013740572",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,219,Tolerated,"30,13","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_059,12,12022877,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His328Pro/c.983A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),17645,209,17984,"0,0116214413",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,452,Tolerated,"30,32","15,17"
"low bq, low freq, many artifacts, many samples",UPN2_060,12,12022877,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His328Pro/c.983A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11023,124,11208,"0,0110635261",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,452,Tolerated,"30,29","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_061,12,12022877,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His328Pro/c.983A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),13884,187,14167,"0,0131996894",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,452,Tolerated,"30,2","16,18"
"low bq, low freq, many artifacts, many samples",UPN2_062,12,12022877,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His328Pro/c.983A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11403,138,11607,"0,0118893771",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,452,Tolerated,30,"14,98"
"low bq, low freq, many artifacts, many samples",UPN2_064,12,12022877,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His328Pro/c.983A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),15755,191,16053,"0,0118980876",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,452,Tolerated,"30,31","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_065,12,12022877,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His328Pro/c.983A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),16544,183,16821,"0,0108792581",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,452,Tolerated,"30,31","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_066,12,12022877,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His328Pro/c.983A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),20541,249,20925,"0,0118996416",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,452,Tolerated,"30,34","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_068,12,12022877,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His328Pro/c.983A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),13789,177,14051,"0,0125969682",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,452,Tolerated,30,"14,59"
"low bq, low freq, many artifacts, many samples",UPN2_069,12,12022877,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His328Pro/c.983A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12634,152,12868,"0,0118122474",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,452,Tolerated,"30,17","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_070,12,12022877,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His328Pro/c.983A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8405,92,8535,"0,0107791447",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,452,Tolerated,"30,08","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_071,12,12022877,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His328Pro/c.983A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8008,100,8157,"0,0122594091",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,452,Tolerated,"30,33","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_073,12,12022877,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His328Pro/c.983A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),8264,100,8406,"0,0118962646",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,452,Tolerated,"30,48","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_074,12,12022877,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His328Pro/c.983A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),9305,105,9459,"0,0111005392",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,452,Tolerated,"30,38","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_075,12,12022877,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His328Pro/c.983A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12453,127,12694,"0,0100047266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,452,Tolerated,"30,51","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_076,12,12022877,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His328Pro/c.983A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11061,120,11259,"0,0106581402",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,452,Tolerated,"30,08","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_077,12,12022877,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His328Pro/c.983A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),16585,176,16887,"0,0104222183",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,452,Tolerated,"30,32","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_078,12,12022877,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His328Pro/c.983A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),11965,166,12230,"0,0135731807",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,452,Tolerated,"30,35","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_079,12,12022877,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His328Pro/c.983A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),6458,68,6573,"0,0103453522",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,452,Tolerated,"30,38","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_081,12,12022877,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His328Pro/c.983A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),15124,158,15397,"0,0102617393",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,452,Tolerated,"30,33","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_082,12,12022877,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His328Pro/c.983A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),20808,215,21165,"0,0101582802",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,452,Tolerated,"30,26","15,25"
"low bq, low freq, many artifacts, many samples",UPN2_083,12,12022877,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His328Pro/c.983A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),14410,189,14705,"0,0128527712",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,452,Tolerated,30,"15,19"
"low bq, low freq, many artifacts, many samples",UPN2_084,12,12022877,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His328Pro/c.983A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),16272,222,16589,"0,0133823618",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,452,Tolerated,30,"14,97"
"low bq, low freq, many artifacts, many samples",UPN2_085,12,12022877,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His328Pro/c.983A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),17442,185,17732,"0,0104331153",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,452,Tolerated,"30,28","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_086,12,12022877,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His328Pro/c.983A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),12208,147,12425,"0,0118309859",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,452,Tolerated,"30,12","14,95"
"low bq, low freq, many artifacts",UPN2_087,12,12022877,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His328Pro/c.983A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),18979,221,19286,"0,0114590895",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,452,Tolerated,"30,24","15,49"
"low freq, many artifacts",UPN2_056,12,12022882,A,C,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met330Leu/c.988A>C|452|ETV6|protein_coding|CODING|ENST00000396373|5|C),5003,67,5116,"0,0130961689",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,82",Neutral,"0,309",Tolerated,"32,15","29,91"
"low freq, many artifacts",UPN2_044,12,12022888,A,G,missense_variant(MODERATE|MISSENSE|Att/Gtt|p.Ile332Val/c.994A>G|452|ETV6|protein_coding|CODING|ENST00000396373|5|G),2681,35,2731,"0,0128158184",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,33",Neutral,"0,13",Tolerated,"32,79","32,77"
"low bq, low freq, many artifacts, many samples",UPN2_001,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),6418,123,6566,"0,0187328663",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,9",16
"low bq, low freq, many artifacts, many samples",UPN2_014,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),9425,190,9641,"0,0197074992",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,54","16,36"
"low bq, low freq, many artifacts, many samples",UPN2_015,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),12854,275,13161,"0,0208950688",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,64",16
"low bq, low freq, many artifacts, many samples",UPN2_016,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),6365,131,6502,"0,0201476469",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,42","15,91"
"low bq, low freq, many artifacts, many samples",UPN2_017,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),4600,95,4707,"0,0201827066",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,67","17,65"
"low bq, low freq, many artifacts, many samples",UPN2_018,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),6795,141,6949,"0,0202906893",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,61","15,82"
"low bq, low freq, many artifacts, many samples",UPN2_019,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),7360,151,7529,"0,0200557843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,8","15,8"
"low bq, low freq, many artifacts, many samples",UPN2_020,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),6487,107,6617,"0,01617047",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,55","16,72"
"low bq, low freq, many artifacts, many samples",UPN2_021,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),6936,154,7106,"0,0216718266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,43","15,97"
"low bq, low freq, many artifacts, many samples",UPN2_002,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),8291,138,8454,"0,0163236338",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,86","15,96"
"low bq, many samples",UPN2_003,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),1508,37,1545,"0,0239482201",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,96","15,54"
"low bq, low freq, many artifacts, many samples",UPN2_022,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),10043,196,10258,"0,0191070384",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,42","15,94"
"low bq, low freq, many artifacts, many samples",UPN2_023,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),11710,247,11989,"0,0206022187",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,52","16,08"
"low bq, many samples",UPN2_041,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),1258,37,1303,"0,0283960092",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"30,61","17,22"
"low bq, many samples",UPN2_024,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),5350,146,5511,"0,0264924696",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,6","15,58"
"low bq, many samples",UPN2_025,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),10967,251,11239,"0,0223329478",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,44","16,36"
"low bq, low freq, many artifacts, many samples",UPN2_026,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),11655,234,11916,"0,0196374622",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,63","15,53"
"low bq, low freq, many artifacts, many samples",UPN2_027,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),12905,268,13196,"0,0203091846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,46","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_089,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),7940,102,8054,"0,0126645145",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,72","15,19"
"low bq, many samples",UPN2_042,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),13836,329,14200,"0,0231690141",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"30,79","16,03"
"low bq, low freq, many artifacts, many samples",UPN2_028,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),8802,170,8995,"0,0188993885",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,74","16,78"
"low bq, low freq, many artifacts, many samples",UPN2_043,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),9885,208,10132,"0,020529017",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"30,78","15,42"
"low bq, many samples",UPN2_044,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),2662,61,2725,"0,0223853211",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"30,7","17,74"
"low bq, many samples",UPN2_029,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),10990,275,11293,"0,0243513681",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,61","17,11"
"low bq, low freq, many artifacts, many samples",UPN2_030,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),10408,216,10642,"0,0202969367",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,65","16,22"
"low bq, low freq, many artifacts, many samples",UPN2_031,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),7088,144,7252,"0,0198565913",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,62","16,06"
"low bq, low freq, many artifacts, many samples",UPN2_005,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),2378,44,2426,"0,0181368508",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,88","16,73"
"low bq, low freq, many artifacts, many samples",UPN2_045,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),13048,287,13376,"0,0214563397",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"30,77","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_032,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),4231,89,4329,"0,0205590206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,47","15,58"
"low bq, many samples",UPN2_046,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),9227,212,9465,"0,0223983096",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"30,66","15,98"
"low bq, low freq, many artifacts, many samples",UPN2_033,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),7820,171,8011,"0,0213456497",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,29","16,13"
"low bq, many samples",UPN2_034,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),3027,74,3109,"0,0238018656",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,73","16,58"
"low bq, low freq, many artifacts, many samples",UPN2_047,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),15674,352,16064,"0,0219123506",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"30,79","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_048,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),7592,166,7786,"0,0213203185",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"30,78","16,48"
"low bq, low freq, many artifacts, many samples",UPN2_035,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),14494,287,14806,"0,0193840335",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,55","16,69"
"low bq, many samples",UPN2_036,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),13802,341,14174,"0,0240581346",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,4","18,07"
"low bq, low freq, many artifacts, many samples",UPN2_006,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),8518,160,8693,"0,0184056137",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,8","16,28"
"low bq, many samples",UPN2_049,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),10693,257,10974,"0,0234189903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"30,74","16,16"
"low bq, low freq, many artifacts, many samples",UPN2_050,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),10187,222,10432,"0,0212806748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"30,82","15,55"
"low bq, low freq, many artifacts, many samples",UPN2_037,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),16706,364,17120,"0,0212616822",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,63","16,35"
"low bq, low freq, many artifacts, many samples",UPN2_051,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),8138,170,8338,"0,0203885824",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"30,88","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_052,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),7798,162,7984,"0,0202905812",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"30,66","16,12"
"low bq, low freq, many artifacts, many samples",UPN2_038,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),17302,373,17718,"0,0210520375",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,59","16,26"
"low bq, low freq, many artifacts, many samples",UPN2_039,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),12316,247,12585,"0,0196265395",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,72","15,81"
"low bq, many samples",UPN2_053,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),13177,304,13522,"0,0224818814",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"30,73","15,65"
"low bq, low freq, many artifacts, many samples",UPN2_054,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),7192,155,7370,"0,0210312076",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"30,83","15,59"
"low bq, low freq, many artifacts, many samples",UPN2_007,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),16286,300,16615,"0,0180559735",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,72","16,59"
"low bq, low freq, many artifacts, many samples",UPN2_008,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),23542,432,24032,"0,017976032",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,77","16,01"
"low bq, low freq, many artifacts, many samples",UPN2_009,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),20882,349,21274,"0,0164050014",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,68","15,57"
"low bq, low freq, many artifacts, many samples",UPN2_010,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),14036,238,14301,"0,0166421929",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,84","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_011,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),18419,346,18800,"0,0184042553",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,76","15,66"
"low bq, low freq, many artifacts, many samples",UPN2_055,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),13008,290,13326,"0,0217619691",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"30,79","16,1"
"low bq, many samples",UPN2_056,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),4953,112,5081,"0,0220429049",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"30,72","15,34"
"low bq, low freq, many artifacts, many samples",UPN2_090,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),7399,88,7497,"0,0117380285",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,85","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_057,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),12376,272,12685,"0,0214426488",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"30,79","15,83"
"low bq, many samples",UPN2_058,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),12659,293,12984,"0,0225662354",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"30,87","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_059,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),17564,340,17927,"0,0189658058",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,21","16,13"
"low bq, low freq, many artifacts, many samples",UPN2_012,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),8700,182,8904,"0,0204402516",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,75","16,99"
"low bq, low freq, many artifacts, many samples",UPN2_060,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),10896,223,11148,"0,0200035881",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,22","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_040,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),9526,187,9739,"0,01920115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,46","15,93"
"low bq, low freq, many artifacts, many samples",UPN2_013,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),5123,102,5238,"0,0194730813",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,84","16,04"
"low bq, low freq, many artifacts, many samples",UPN2_091,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),7306,85,7409,"0,0114725334",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,64","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_092,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),4431,58,4499,"0,0128917537",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,67","15,41"
"low bq, low freq, many artifacts, many samples",UPN2_093,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),5223,56,5291,"0,0105840106",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,89","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_061,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),13809,269,14118,"0,0190536903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,11","15,91"
"low bq, low freq, many artifacts, many samples",UPN2_062,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),11304,190,11517,"0,0164973517",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,15","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_063,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),11199,197,11424,"0,0172443978",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,2","15,73"
"low bq, low freq, many artifacts, many samples",UPN2_064,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),15662,302,16000,"0,018875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,08","16,11"
"low bq, low freq, many artifacts, many samples",UPN2_065,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),16394,307,16726,"0,0183546574",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,15","15,51"
"low bq, low freq, many artifacts, many samples",UPN2_066,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),20375,385,20797,"0,0185122854",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,17","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_067,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),21056,433,21524,"0,0201170786",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,11","16,55"
"low bq, low freq, many artifacts, many samples",UPN2_068,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),13662,228,13925,"0,0163734291",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,22","15,62"
"low bq, low freq, many artifacts, many samples",UPN2_069,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),12517,243,12800,"0,018984375",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,09","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_070,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),8324,138,8490,"0,016254417",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,24","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_071,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),7924,165,8107,"0,0203527815",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"30,98","16,95"
"low bq, low freq, many artifacts, many samples",UPN2_072,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),10774,218,11009,"0,0198019802",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,13","16,17"
"low bq, low freq, many artifacts, many samples",UPN2_073,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),8224,136,8383,"0,0162233091",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,11","16,62"
"low bq, low freq, many artifacts, many samples",UPN2_074,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),9215,176,9406,"0,0187114608",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,22","16,02"
"low bq, low freq, many artifacts, many samples",UPN2_075,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),12363,230,12629,"0,0182120516",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,21","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_076,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),10980,221,11221,"0,0196952143",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,16","16,33"
"low bq, low freq, many artifacts, many samples",UPN2_077,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),16528,276,16842,"0,0163876024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,22","15,49"
"low bq, low freq, many artifacts, many samples",UPN2_078,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),11898,223,12160,"0,0183388158",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,19","16,31"
"low bq, low freq, many artifacts, many samples",UPN2_079,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),6409,116,6554,"0,017699115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,13","15,66"
"low bq, low freq, many artifacts, many samples",UPN2_080,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),11441,200,11670,"0,0171379606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,17","15,51"
"low bq, low freq, many artifacts, many samples",UPN2_081,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),15024,276,15325,"0,0180097879",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,09","16,38"
"low bq, low freq, many artifacts, many samples",UPN2_082,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),20589,385,21016,"0,0183193757",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,2","15,41"
"low bq, low freq, many artifacts, many samples",UPN2_083,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),14366,243,14633,"0,0166063008",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,15","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_084,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),16144,305,16496,"0,0184893307",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,23","15,73"
"low bq, low freq, many artifacts, many samples",UPN2_085,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),17257,311,17615,"0,0176554073",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,14","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_086,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),12074,227,12330,"0,0184103812",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,12","15,76"
"low bq, low freq, many artifacts, many samples",UPN2_087,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),18762,381,19187,"0,019857195",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,24","15,68"
"low bq, low freq, many artifacts, many samples",UPN2_088,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),13015,254,13292,"0,0191092386",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,13","15,57"
"low bq, low freq, many artifacts, many samples",UPN2_094,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),9089,112,9223,"0,0121435542",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,72","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_095,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),7792,83,7891,"0,010518312",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,7","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_096,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),9265,116,9396,"0,012345679",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,68","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_097,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),9518,104,9640,"0,0107883817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,77","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_098,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),8839,96,8957,"0,0107178743",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,7","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_099,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),4301,56,4370,"0,0128146453",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,83","16,59"
"low bq, low freq, many artifacts, many samples",UPN2_100,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),7295,85,7389,"0,0115035864",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,87","15,39"
"low bq, low freq, many artifacts, many samples",UPN2_101,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),7335,86,7440,"0,0115591398",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,73","15,84"
"low bq, low freq, many artifacts, many samples",UPN2_102,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),8494,122,8630,"0,0141367323",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,69","16,93"
"low bq, low freq, many artifacts, many samples",UPN2_103,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),7161,82,7250,"0,0113103448",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,78","16,2"
"low bq, low freq, many artifacts, many samples",UPN2_104,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),9113,114,9243,"0,0123336579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,84","16,27"
"low bq, low freq, many artifacts, many samples",UPN2_105,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),8242,103,8356,"0,012326472",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,8","15,37"
"low bq, low freq, many artifacts, many samples",UPN2_106,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),11861,147,12024,"0,0122255489",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,73","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_107,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),14631,175,14840,"0,0117924528",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,74","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_108,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),10396,141,10562,"0,0133497444",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,83","15,96"
"low bq, low freq, many artifacts, many samples",UPN2_109,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),11153,119,11288,"0,0105421687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,66","15,41"
"low bq, low freq, many artifacts, many samples",UPN2_110,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),11951,136,12111,"0,0112294608",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,7","14,23"
"low bq, low freq, many artifacts",UPN2_111,12,12022898,T,A,missense_variant(MODERATE|MISSENSE|aTa/aAa|p.Ile335Lys/c.1004T>A|452|ETV6|protein_coding|CODING|ENST00000396373|5|A),9669,110,9806,"0,0112176219",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,0,Damaging,"31,51","15,64"
"low freq, many artifacts",UPN2_044,12,12037441,A,G,missense_variant(MODERATE|MISSENSE|Atc/Gtc|p.Ile358Val/c.1072A>G|452|ETV6|protein_coding|CODING|ENST00000396373|6|G),9548,124,9715,"0,0127637674",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,0,Damaging,"32,73","32,4"
"low freq, many artifacts",UPN2_048,12,12037462,T,C,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser365Pro/c.1093T>C|452|ETV6|protein_coding|CODING|ENST00000396373|6|C),11186,165,11370,"0,0145118734",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,72",Deleterious,"0,024",Damaging,"33,96",32
"low bq, low freq, many artifacts",UPN2_048,12,12037468,A,T,missense_variant(MODERATE|MISSENSE|Ata/Tta|p.Ile367Leu/c.1099A>T|452|ETV6|protein_coding|CODING|ENST00000396373|6|T),11222,116,11378,"0,0101951134",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,36",Neutral,129,Tolerated,"33,03","25,3"
"inspected, many artifacts",UPN2_076,12,12037473,C,A,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe368Leu/c.1104C>A|452|ETV6|protein_coding|CODING|ENST00000396373|6|A),41932,1072,43120,"0,0248608534",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,06",Deleterious,0,Damaging,"32,01","31,71"
"low freq, many artifacts",UPN2_044,12,12037507,TG,T,frameshift_variant(HIGH||gga/|p.Gly381fs/c.1142delG|452|ETV6|protein_coding|CODING|ENST00000396373|6|T|INFO_REALIGN_3_PRIME),4749,71,4842,"0,0146633622",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,17",NA
"low bq, low freq, many artifacts",UPN2_044,12,12037511,G,T,missense_variant(MODERATE|MISSENSE|gGa/gTa|p.Gly381Val/c.1142G>T|452|ETV6|protein_coding|CODING|ENST00000396373|6|T),4783,50,4844,"0,0103220479",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,19",Deleterious,0,Damaging,"34,27","26,86"
"low freq, many artifacts",UPN2_048,12,12037513,A,T,missense_variant(MODERATE|MISSENSE|Aac/Tac|p.Asn382Tyr/c.1144A>T|452|ETV6|protein_coding|CODING|ENST00000396373|6|T),5560,81,5663,"0,0143033728",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,02",Deleterious,"0,021",Damaging,"34,58","29,31"
"low bq, low freq, many artifacts",UPN2_056,12,12037517,A,T,missense_variant(MODERATE|MISSENSE|cAt/cTt|p.His383Leu/c.1148A>T|452|ETV6|protein_coding|CODING|ENST00000396373|6|T),6419,108,6546,"0,0164986251",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,77",Deleterious,"0,005",Damaging,"33,99","26,46"
"low freq, many artifacts",UPN2_048,12,12038867,C,T,missense_variant(MODERATE|MISSENSE|aCa/aTa|p.Thr387Ile/c.1160C>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),1451,22,1474,"0,0149253731",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,"0,413",Tolerated,"35,44",35
"low freq, many artifacts",UPN2_056,12,12038882,A,G,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu392Gly/c.1175A>G|452|ETV6|protein_coding|CODING|ENST00000396373|7|G),2056,25,2081,"0,0120134551",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,"0,001",Damaging,"35,33","34,6"
"low freq, many artifacts",UPN2_048,12,12038887,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met394Leu/c.1180A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),1447,23,1473,"0,0156143924",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,22",Neutral,"0,18",Tolerated,"35,48","35,04"
"low freq, many artifacts",UPN2_048,12,12038896,G,T,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala397Ser/c.1189G>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),1443,29,1473,"0,0196877122",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,46",Neutral,"0,006",Damaging,"34,86","33,41"
"low freq, many artifacts",UPN2_071,12,12038905,C,T,missense_variant(MODERATE|MISSENSE|Cac/Tac|p.His400Tyr/c.1198C>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),1953,22,1981,"0,0111055023",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,5",Deleterious,"0,387",Tolerated,"33,2","33,82"
"low freq, many artifacts",UPN2_056,12,12038929,A,G,missense_variant(MODERATE|MISSENSE|Agg/Ggg|p.Arg408Gly/c.1222A>G|452|ETV6|protein_coding|CODING|ENST00000396373|7|G),2054,21,2080,"0,0100961538",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,92",Deleterious,"0,003",Damaging,"34,71","31,57"
"low bq, low freq, many artifacts",UPN2_060,12,12038932,A,C,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),6945,78,7137,"0,0109289617",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,05",Deleterious,3,Damaging,"29,7","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_001,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),7965,83,8068,"0,0102875558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,15","16,83"
"low bq, low freq, many artifacts, many samples",UPN2_014,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),13062,199,13338,"0,0149197781",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,92","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_016,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),9123,127,9289,"0,0136720853",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,83","15,91"
"low bq, low freq, many artifacts, many samples",UPN2_017,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),6470,74,6574,"0,0112564649",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,42","16,84"
"low bq, low freq, many artifacts, many samples",UPN2_018,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),9920,118,10087,"0,0116982254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,3","15,31"
"low bq, low freq, many artifacts, many samples",UPN2_019,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),11181,138,11355,"0,0121532365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,38","15,56"
"low bq, low freq, many artifacts, many samples",UPN2_020,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),9086,97,9210,"0,0105320304",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,48","15,3"
"low bq, low freq, many artifacts, many samples",UPN2_021,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),9450,104,9587,"0,0108480234",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,25","15,58"
"low bq, low freq, many artifacts, many samples",UPN2_022,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),13367,147,13575,"0,0108287293",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,21","15,37"
"low bq, low freq, many artifacts, many samples",UPN2_023,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),14617,164,14864,"0,0110333692",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,86","15,68"
"low bq, low freq, many artifacts, many samples",UPN2_024,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),6497,73,6605,"0,0110522332",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,55","16,67"
"low bq, low freq, many artifacts, many samples",UPN2_025,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),15898,203,16174,"0,0125510078",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,31,"15,76"
"low bq, low freq, many artifacts, many samples",UPN2_042,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),17853,259,18223,"0,014212808",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,89","16,03"
"low bq, low freq, many artifacts, many samples",UPN2_028,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),11920,123,12105,"0,0101610905",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,45","15,59"
"low bq, low freq, many artifacts, many samples",UPN2_043,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),13969,221,14291,"0,0154642782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,08","15,49"
"low bq, low freq, many artifacts, many samples",UPN2_044,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),2467,37,2522,"0,0146708961",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,03","16,43"
"low bq, low freq, many artifacts, many samples",UPN2_029,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),12901,148,13105,"0,0112933995",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,45","15,74"
"low bq, low freq, many artifacts, many samples",UPN2_030,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),14685,183,14928,"0,0122588424",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,3","17,32"
"low bq, low freq, many artifacts, many samples",UPN2_031,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),9712,133,9902,"0,01343163",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,08","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_045,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),18512,258,18893,"0,0136558514",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,05","15,64"
"low bq, low freq, many artifacts, many samples",UPN2_032,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),4990,60,5067,"0,0118413262",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,86","15,42"
"low bq, low freq, many artifacts, many samples",UPN2_046,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),16865,231,17186,"0,013441173",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,11","15,34"
"low bq, low freq, many artifacts, many samples",UPN2_033,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),10476,166,10698,"0,0155169191",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,04","16,25"
"low bq, low freq, many artifacts, many samples",UPN2_047,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),20303,302,20719,"0,014575993",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,17","16,43"
"low bq, low freq, many artifacts, many samples",UPN2_048,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),2806,36,2854,"0,0126138753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,96",15
"low bq, low freq, many artifacts, many samples",UPN2_035,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),16106,219,16410,"0,013345521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,12","15,34"
"low bq, low freq, many artifacts, many samples",UPN2_036,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),15186,186,15442,"0,0120450719",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,9","15,63"
"low bq, low freq, many artifacts, many samples",UPN2_049,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),11356,154,11589,"0,0132884632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,31,"15,94"
"low bq, low freq, many artifacts, many samples",UPN2_050,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),16674,281,17031,"0,0164993248",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,02","17,03"
"low bq, low freq, many artifacts, many samples",UPN2_037,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),20663,212,20968,"0,0101106448",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,51","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_051,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),14121,196,14412,"0,013599778",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,11","15,87"
"low bq, low freq, many artifacts, many samples",UPN2_052,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),12685,156,12910,"0,0120836561",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,25","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_038,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),23912,307,24324,"0,0126212794",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,31","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_039,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),21743,258,22103,"0,0116726236",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,37","17,02"
"low bq, low freq, many artifacts, many samples",UPN2_053,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),19867,280,20255,"0,0138237472",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,15","17,07"
"low bq, low freq, many artifacts, many samples",UPN2_054,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),13463,171,13703,"0,0124790192",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,04","15,97"
"low bq, low freq, many artifacts, many samples",UPN2_007,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),20266,207,20574,"0,0100612423",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,16","15,69"
"low bq, low freq, many artifacts, many samples",UPN2_055,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),19200,249,19577,"0,012719007",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,14","16,56"
"low bq, low freq, many artifacts, many samples",UPN2_056,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),3953,55,4022,"0,0136747887",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,03","16,98"
"low bq, low freq, many artifacts, many samples",UPN2_057,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),16313,256,16677,"0,0153504827",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,01","16,05"
"low bq, low freq, many artifacts, many samples",UPN2_058,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),15611,268,15946,"0,0168067227",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,06","15,59"
"low bq, low freq, many artifacts, many samples",UPN2_059,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),7558,107,7752,"0,0138028896",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,99","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_040,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),9101,102,9236,"0,0110437419",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,32","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_061,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),7260,85,7405,"0,0114787306",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,18","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_062,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),5947,81,6095,"0,0132895816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,89","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_063,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),6129,74,6270,"0,0118022329",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,31",14
"low bq, low freq, many artifacts, many samples",UPN2_064,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),6925,93,7090,"0,0131170663",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,04","16,04"
"low bq, low freq, many artifacts, many samples",UPN2_065,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),8696,136,8933,"0,0152244487",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,89","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_066,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),14408,233,14836,"0,0157050418",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,73","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_067,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),12947,208,13303,"0,0156355709",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,86","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_068,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),9137,111,9323,"0,0119060388",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,45","15,71"
"low bq, low freq, many artifacts, many samples",UPN2_069,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),9868,145,10083,"0,0143806407",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,09","15,81"
"low bq, low freq, many artifacts, many samples",UPN2_070,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),6273,92,6430,"0,0143079316",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,11","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_071,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),3757,53,3837,"0,0138128746",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,32","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_072,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),5084,75,5204,"0,0144119908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,35","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_073,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),5290,85,5415,"0,0156971376",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,87","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_074,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),6100,88,6245,"0,014091273",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,76","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_075,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),6722,117,6911,"0,0169295326",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,97","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_076,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),6827,92,6985,"0,0131710809",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,4","15,45"
"low bq, low freq, many artifacts, many samples",UPN2_077,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),9289,139,9511,"0,0146146567",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,18","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_078,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),6045,78,6181,"0,0126193173",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,14","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_080,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),5184,58,5280,"0,0109848485",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,24","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_081,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),6690,96,6857,"0,0140002917",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,88","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_082,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),12173,198,12522,"0,0158121706",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,82","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_083,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),8728,111,8931,"0,0124286194",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,44","15,66"
"low bq, low freq, many artifacts, many samples",UPN2_084,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),9731,119,9955,"0,0119537921",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,3","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_085,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),9451,131,9662,"0,0135582695",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,22","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_086,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),7390,118,7582,"0,0155631759",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,2","16,03"
"low bq, low freq, many artifacts, many samples",UPN2_087,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),11518,154,11776,"0,0130774457",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,44","14,96"
"low bq, low freq, many artifacts",UPN2_088,12,12038932,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys409*/c.1225A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),9488,168,9737,"0,0172537743",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,89","15,07"
"low freq, many artifacts",UPN2_044,12,12038940,AG,A,frameshift_variant(HIGH||gga/|p.Gly412fs/c.1235delG|452|ETV6|protein_coding|CODING|ENST00000396373|7|A|INFO_REALIGN_3_PRIME),2492,31,2548,"0,012166405",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,76",NA
"low freq, many artifacts",UPN2_006,12,12038945,A,G,missense_variant(MODERATE|MISSENSE|cAa/cGa|p.Gln413Arg/c.1238A>G|452|ETV6|protein_coding|CODING|ENST00000396373|7|G),9445,119,9639,"0,012345679",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,23",Deleterious,"0,005",Damaging,"33,06","34,51"
"low bq, low freq, many artifacts, many samples",UPN2_042,12,12038945,A,T,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln413Leu/c.1238A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),18086,196,18412,"0,0106452314",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,1,Damaging,"31,86","18,17"
"low bq, low freq, many artifacts, many samples",UPN2_043,12,12038945,A,T,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln413Leu/c.1238A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),14180,178,14442,"0,0123251627",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,1,Damaging,"31,86","17,67"
"low bq, low freq, many artifacts, many samples",UPN2_046,12,12038945,A,T,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln413Leu/c.1238A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),17071,182,17348,"0,0104911229",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,1,Damaging,"32,08","17,57"
"low bq, low freq, many artifacts, many samples",UPN2_047,12,12038945,A,T,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln413Leu/c.1238A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),20481,267,20923,"0,0127610763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,1,Damaging,32,"20,53"
"low bq, low freq, many artifacts, many samples",UPN2_048,12,12038945,A,T,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln413Leu/c.1238A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),2820,34,2873,"0,0118343195",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,1,Damaging,"31,81","17,71"
"low bq, low freq, many artifacts, many samples",UPN2_049,12,12038945,A,T,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln413Leu/c.1238A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),11523,119,11728,"0,0101466576",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,1,Damaging,"32,04","19,39"
"low bq, low freq, many artifacts, many samples",UPN2_050,12,12038945,A,T,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln413Leu/c.1238A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),16851,202,17191,"0,0117503345",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,1,Damaging,"32,01","19,3"
"low bq, low freq, many artifacts, many samples",UPN2_051,12,12038945,A,T,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln413Leu/c.1238A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),14304,183,14580,"0,0125514403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,1,Damaging,"32,01","16,75"
"low bq, low freq, many artifacts, many samples",UPN2_053,12,12038945,A,T,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln413Leu/c.1238A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),20133,233,20480,"0,0113769531",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,1,Damaging,"32,05","19,02"
"low bq, low freq, many artifacts, many samples",UPN2_054,12,12038945,A,T,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln413Leu/c.1238A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),13582,160,13856,"0,0115473441",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,1,Damaging,"32,06","17,68"
"low bq, low freq, many artifacts, many samples",UPN2_055,12,12038945,A,T,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln413Leu/c.1238A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),19485,204,19812,"0,0102967898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,1,Damaging,"31,97","17,83"
"low bq, low freq, many artifacts, many samples",UPN2_056,12,12038945,A,T,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln413Leu/c.1238A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),4011,45,4069,"0,0110592283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,1,Damaging,"31,95","17,4"
"low bq, low freq, many artifacts, many samples",UPN2_057,12,12038945,A,T,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln413Leu/c.1238A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),16540,203,16859,"0,0120410463",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,1,Damaging,"31,92","19,39"
"low bq, low freq, many artifacts, many samples",UPN2_058,12,12038945,A,T,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln413Leu/c.1238A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),15823,210,16131,"0,0130184118",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,1,Damaging,"32,02","16,99"
"low bq, low freq, many artifacts, many samples",UPN2_060,12,12038945,A,T,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln413Leu/c.1238A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),7113,79,7234,"0,0109206525",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,1,Damaging,"31,33","17,29"
"low bq, low freq, many artifacts, many samples",UPN2_063,12,12038945,A,T,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln413Leu/c.1238A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),6262,77,6364,"0,0120993086",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,1,Damaging,"31,14","17,84"
"low bq, low freq, many artifacts, many samples",UPN2_064,12,12038945,A,T,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln413Leu/c.1238A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),7071,74,7178,"0,0103092784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,1,Damaging,"31,22","19,18"
"low bq, low freq, many artifacts, many samples",UPN2_065,12,12038945,A,T,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln413Leu/c.1238A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),8900,92,9045,"0,0101713654",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,1,Damaging,"31,32","18,02"
"low bq, low freq, many artifacts, many samples",UPN2_066,12,12038945,A,T,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln413Leu/c.1238A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),14789,165,15042,"0,010969286",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,1,Damaging,"31,39","17,36"
"low bq, low freq, many artifacts, many samples",UPN2_067,12,12038945,A,T,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln413Leu/c.1238A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),13255,170,13507,"0,0125860665",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,1,Damaging,"31,27","16,98"
"low bq, low freq, many artifacts, many samples",UPN2_069,12,12038945,A,T,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln413Leu/c.1238A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),10054,113,10218,"0,0110589156",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,1,Damaging,"31,28","18,13"
"low bq, low freq, many artifacts, many samples",UPN2_070,12,12038945,A,T,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln413Leu/c.1238A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),6428,66,6521,"0,0101211471",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,1,Damaging,"31,3","17,8"
"low bq, low freq, many artifacts, many samples",UPN2_071,12,12038945,A,T,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln413Leu/c.1238A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),3808,57,3881,"0,0146869364",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,1,Damaging,"31,15","15,77"
"low bq, low freq, many artifacts, many samples",UPN2_072,12,12038945,A,T,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln413Leu/c.1238A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),5168,67,5266,"0,0127231295",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,1,Damaging,"31,26","15,58"
"low bq, low freq, many artifacts, many samples",UPN2_073,12,12038945,A,T,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln413Leu/c.1238A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),5382,65,5476,"0,0118699781",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,1,Damaging,"31,38","16,05"
"low bq, low freq, many artifacts, many samples",UPN2_074,12,12038945,A,T,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln413Leu/c.1238A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),6240,66,6331,"0,0104248934",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,1,Damaging,"31,27","15,71"
"low bq, low freq, many artifacts, many samples",UPN2_077,12,12038945,A,T,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln413Leu/c.1238A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),9491,97,9622,"0,0100810642",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,1,Damaging,"31,22","16,19"
"low bq, low freq, many artifacts, many samples",UPN2_078,12,12038945,A,T,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln413Leu/c.1238A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),6142,73,6257,"0,011666933",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,1,Damaging,"31,18","19,07"
"low bq, low freq, many artifacts, many samples",UPN2_079,12,12038945,A,T,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln413Leu/c.1238A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),3495,40,3557,"0,0112454315",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,1,Damaging,"31,43","18,85"
"low bq, low freq, many artifacts, many samples",UPN2_080,12,12038945,A,T,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln413Leu/c.1238A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),5275,60,5364,"0,0111856823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,1,Damaging,"31,49","18,35"
"low bq, low freq, many artifacts, many samples",UPN2_082,12,12038945,A,T,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln413Leu/c.1238A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),12488,160,12709,"0,0125895035",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,1,Damaging,"31,3","17,52"
"low bq, low freq, many artifacts, many samples",UPN2_084,12,12038945,A,T,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln413Leu/c.1238A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),9919,114,10075,"0,0113151365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,1,Damaging,"31,25","16,05"
"low bq, low freq, many artifacts",UPN2_085,12,12038945,A,T,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln413Leu/c.1238A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),9616,114,9770,"0,0116683726",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,4",Deleterious,1,Damaging,"31,3","16,88"
"low bq, low freq, many artifacts, many samples",UPN2_002,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),10760,117,10916,"0,0107182118",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"32,93","21,03"
"low bq, low freq, many artifacts, many samples",UPN2_042,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),18103,216,18426,"0,0117225659",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"31,64","16,4"
"low bq, low freq, many artifacts, many samples",UPN2_043,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),14231,171,14454,"0,0118306351",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"31,76","15,53"
"low bq, low freq, many artifacts, many samples",UPN2_044,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),2511,36,2554,"0,0140955364",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"31,76","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_045,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),18818,209,19119,"0,0109315341",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"31,81","16,54"
"low bq, low freq, many artifacts, many samples",UPN2_046,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),17040,211,17363,"0,0121522778",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"31,74","17,71"
"low bq, low freq, many artifacts, many samples",UPN2_047,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),20597,227,20933,"0,0108441217",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"31,74","16,86"
"low bq, low freq, many artifacts, many samples",UPN2_048,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),2831,35,2876,"0,0121696801",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"31,75","16,51"
"low bq, low freq, many artifacts, many samples",UPN2_049,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),11511,154,11737,"0,0131208997",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"31,86","16,74"
"low bq, low freq, many artifacts, many samples",UPN2_050,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),16902,183,17197,"0,0106413909",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"31,85","17,42"
"low bq, low freq, many artifacts, many samples",UPN2_051,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),14361,179,14589,"0,0122695181",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"31,8","16,41"
"low bq, low freq, many artifacts, many samples",UPN2_052,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),12797,174,13017,"0,0133671353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"31,89","17,93"
"low bq, low freq, many artifacts, many samples",UPN2_053,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),20167,241,20488,"0,0117629832",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"31,75","17,22"
"low bq, low freq, many artifacts, many samples",UPN2_054,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),13649,144,13865,"0,0103858637",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"31,78","16,62"
"low bq, low freq, many artifacts, many samples",UPN2_055,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),19523,205,19818,"0,0103441316",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"31,74","17,1"
"low bq, low freq, many artifacts, many samples",UPN2_056,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),3999,50,4071,"0,0122819946",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"31,9","16,12"
"low bq, low freq, many artifacts, many samples",UPN2_057,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),16589,213,16867,"0,0126282089",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"31,79","17,12"
"low bq, low freq, many artifacts, many samples",UPN2_058,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),15872,191,16149,"0,0118273577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"31,83","18,01"
"low bq, low freq, many artifacts, many samples",UPN2_059,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),7673,105,7835,"0,013401404",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"30,06","15,41"
"low bq, low freq, many artifacts, many samples",UPN2_060,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),7103,94,7236,"0,0129906025",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"29,9","16,72"
"low bq, low freq, many artifacts, many samples",UPN2_061,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),7363,85,7500,"0,0113333333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"29,91","17,49"
"low bq, low freq, many artifacts, many samples",UPN2_062,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),6059,76,6170,"0,0123176661",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"29,8","15,45"
"low bq, low freq, many artifacts, many samples",UPN2_063,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),6246,94,6368,"0,0147613065",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"30,06","19,3"
"low bq, low freq, many artifacts, many samples",UPN2_064,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),7040,99,7183,"0,0137825421",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"30,07","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_065,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),8886,112,9049,"0,0123770582",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"30,05","17,71"
"low bq, low freq, many artifacts, many samples",UPN2_066,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),14786,178,15049,"0,0118280284",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,30,"15,71"
"low bq, low freq, many artifacts, many samples",UPN2_067,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),13270,175,13518,"0,012945702",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,30,"15,81"
"low bq, low freq, many artifacts, many samples",UPN2_068,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),9258,113,9420,"0,0119957537",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"29,94","15,64"
"low bq, low freq, many artifacts, many samples",UPN2_069,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),10029,130,10223,"0,0127164238",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"30,07","15,45"
"low bq, low freq, many artifacts, many samples",UPN2_070,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),6401,83,6524,"0,0127222563",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"29,93","15,25"
"low bq, low freq, many artifacts, many samples",UPN2_071,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),3791,64,3883,"0,0164821015",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"30,06","15,58"
"low bq, low freq, many artifacts, many samples",UPN2_072,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),5163,72,5271,"0,0136596471",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"30,07","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_074,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),6224,88,6335,"0,0138910813",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"29,86","16,81"
"low bq, low freq, many artifacts, many samples",UPN2_075,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),6877,87,7004,"0,0124214734",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"30,13","16,52"
"low bq, low freq, many artifacts, many samples",UPN2_077,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),9441,105,9631,"0,0109022947",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"30,04","15,93"
"low bq, low freq, many artifacts, many samples",UPN2_078,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),6158,66,6261,"0,0105414471",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"29,92","16,62"
"low bq, low freq, many artifacts, many samples",UPN2_079,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),3498,48,3560,"0,0134831461",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"29,96","16,1"
"low bq, low freq, many artifacts, many samples",UPN2_080,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),5264,70,5368,"0,0130402385",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"30,06","19,31"
"low bq, low freq, many artifacts, many samples",UPN2_081,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),6844,98,6981,"0,0140381034",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"30,17","15,95"
"low bq, low freq, many artifacts, many samples",UPN2_082,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),12484,160,12717,"0,0125815837",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"30,04","17,41"
"low bq, low freq, many artifacts, many samples",UPN2_083,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),8871,123,9042,"0,0136031851",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"29,9","18,68"
"low bq, low freq, many artifacts, many samples",UPN2_084,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),9902,125,10082,"0,0123983337",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"30,01","15,86"
"low bq, low freq, many artifacts, many samples",UPN2_085,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),9611,127,9775,"0,0129923274",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"29,97","16,21"
"low bq, low freq, many artifacts, many samples",UPN2_086,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),7568,93,7696,"0,0120841996",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"29,83","17,13"
"low bq, low freq, many artifacts, many samples",UPN2_087,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),11740,143,11939,"0,0119775526",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"29,98","16,94"
"low bq, low freq, many artifacts",UPN2_088,12,12038946,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln413His/c.1239A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),9706,117,9876,"0,0118469016",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,1,Damaging,"30,21","15,36"
"low bq, low freq, many artifacts",UPN2_044,12,12038947,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg414Trp/c.1240A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),2511,35,2558,"0,0136825645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,02",Deleterious,0,Damaging,"31,68","19,43"
"low freq, many artifacts",UPN2_081,12,12038950,C,T,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu415Phe/c.1243C>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),6891,80,7010,"0,0114122682",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,16",Deleterious,"0,039",Damaging,"31,55","28,58"
"low bq, low freq, many artifacts, many samples",UPN2_062,12,12038951,T,G,missense_variant(MODERATE|MISSENSE|cTt/cGt|p.Leu415Arg/c.1244T>G|452|ETV6|protein_coding|CODING|ENST00000396373|7|G),6080,62,6198,"0,0100032268",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,66",Deleterious,9,Damaging,"29,83","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_074,12,12038951,T,G,missense_variant(MODERATE|MISSENSE|cTt/cGt|p.Leu415Arg/c.1244T>G|452|ETV6|protein_coding|CODING|ENST00000396373|7|G),6264,70,6373,"0,0109838381",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,66",Deleterious,9,Damaging,"30,17","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_076,12,12038958,C,G,missense_variant+splice_region_variant(MODERATE|MISSENSE|ttC/ttG|p.Phe417Leu/c.1251C>G|452|ETV6|protein_coding|CODING|ENST00000396373|7|G),6997,78,7109,"0,0109720073",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,75",Deleterious,7,Damaging,"31,56","24,06"
"low bq, low freq, many artifacts, many samples",UPN2_071,12,12038959,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg418Trp/c.1252A>T|452|ETV6|protein_coding|CODING|ENST00000396373|7|T),3842,42,3900,"0,0107692308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,52",Deleterious,0,Damaging,"32,63","18,81"
"low freq, many artifacts",UPN2_044,12,12043894,G,A,missense_variant(MODERATE|MISSENSE|Gaa/Aaa|p.Glu425Lys/c.1273G>A|452|ETV6|protein_coding|CODING|ENST00000396373|8|A),2460,47,2510,"0,0187250996",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,38",Neutral,"0,246",Tolerated,"34,74","32,38"
"low freq, many artifacts",UPN2_044,12,12043931,T,A,missense_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu437Gln/c.1310T>A|452|ETV6|protein_coding|CODING|ENST00000396373|8|A),2468,36,2509,"0,014348346",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,22",Deleterious,"0,004",Damaging,"33,79","32,11"
"inspected, strandbias",UPN2_041,12,12043949,A,G,missense_variant(MODERATE|MISSENSE|gAt/gGt|p.Asp443Gly/c.1328A>G|452|ETV6|protein_coding|CODING|ENST00000396373|8|G),1130,111,1296,"0,0856481481",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,003",Damaging,"31,27","31,43"
"low bq, low freq, many artifacts, many samples",UPN2_001,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),8437,182,8639,"0,0210672532",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,59","15,68"
"low bq, many samples",UPN2_014,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),11674,411,12134,"0,0338717653",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,51","15,15"
"low bq, many samples",UPN2_015,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),17071,529,17656,"0,0299614862",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,75","15,85"
"low bq, many samples",UPN2_016,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),7763,281,8056,"0,0348808342",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,33","15,3"
"low bq, many samples",UPN2_017,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),5895,180,6090,"0,0295566502",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,62","15,49"
"low bq, many samples",UPN2_018,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),9159,313,9504,"0,0329335017",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,61","15,17"
"low bq, many samples",UPN2_019,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),10264,308,10613,"0,029021012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,64","15,27"
"low bq, many samples",UPN2_020,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),7912,270,8200,"0,0329268293",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,39","15,1"
"low bq, many samples",UPN2_021,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),8671,275,8962,"0,0306851149",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,45","15,95"
"low bq, low freq, many artifacts, many samples",UPN2_002,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),10664,208,10898,"0,0190860708",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,71","16,22"
"low bq, low freq, many artifacts, many samples",UPN2_003,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),2073,43,2118,"0,0203021719",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,98","17,28"
"low bq, many samples",UPN2_022,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),12658,396,13083,"0,0302682871",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,51","15,08"
"low bq, many samples",UPN2_023,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),12822,421,13267,"0,031732871",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,51","15,89"
"low bq, many samples",UPN2_024,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),6869,218,7095,"0,0307258633",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,53","15,26"
"low bq, many samples",UPN2_025,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),14558,474,15073,"0,0314469581",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,37","15,55"
"low bq, many samples",UPN2_026,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),14865,474,15379,"0,0308212498",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,64","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_004,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),2205,36,2241,"0,016064257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,77","14,36"
"low bq, many samples",UPN2_027,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),14159,472,14672,"0,03217012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,66","15,73"
"low bq, low freq, many artifacts, many samples",UPN2_089,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),10218,119,10365,"0,0114809455",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,82","15,39"
"low bq, many samples",UPN2_042,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),25424,1031,26559,"0,0388192327",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,46","16,46"
"low bq, many samples",UPN2_028,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),11093,315,11445,"0,0275229358",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,8","15,31"
"low bq, many samples",UPN2_043,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),16582,680,17315,"0,0392723072",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,36","16,21"
"low bq, many samples",UPN2_044,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),4672,226,4918,"0,0459536397",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,47","15,98"
"low bq, many samples",UPN2_029,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),12867,421,13334,"0,0315734213",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,46","15,45"
"low bq, many samples",UPN2_030,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),14316,429,14788,"0,0290100081",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,46","15,42"
"low bq, many samples",UPN2_031,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),9103,286,9429,"0,0303319546",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,51","15,54"
"low bq, low freq, many artifacts, many samples",UPN2_005,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),2932,50,2988,"0,0167336011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,57","14,78"
"low bq, many samples",UPN2_045,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),22857,913,23878,"0,0382360332",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,54","16,04"
"low bq, many samples",UPN2_032,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),4704,139,4868,"0,0285538209",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,48","14,82"
"low bq, many samples",UPN2_046,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),18471,705,19258,"0,0366081628",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,51","15,77"
"low bq, many samples",UPN2_033,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),9522,347,9901,"0,035046965",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,34","15,4"
"low bq, many samples",UPN2_034,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),3798,134,3945,"0,0339670469",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,57","16,22"
"low bq, many samples",UPN2_047,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),27411,1104,28625,"0,0385676856",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,49","15,95"
"low bq, many samples",UPN2_048,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),6589,278,6916,"0,0401966455",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,3","16,29"
"low bq, many samples",UPN2_035,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),18213,596,18873,"0,0315795051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,51","15,49"
"low bq, many samples",UPN2_036,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),17076,521,17631,"0,029550224",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,6","15,5"
"low bq, low freq, many artifacts, many samples",UPN2_006,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),11585,213,11821,"0,0180187801",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,69","15,3"
"low bq, many samples",UPN2_049,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),17502,674,18246,"0,0369396032",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,51","15,55"
"low bq, many samples",UPN2_050,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),21177,798,22069,"0,0361593185",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,61","15,91"
"low bq, many samples",UPN2_037,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),20261,637,20965,"0,0303839733",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,66","15,53"
"low bq, many samples",UPN2_051,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),17347,724,18110,"0,0399779128",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,52","16,16"
"low bq, many samples",UPN2_052,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),15682,618,16349,"0,0378004771",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,66","16,17"
"low bq, many samples",UPN2_038,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),23180,678,23928,"0,028335005",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,65","15,95"
"low bq, many samples",UPN2_039,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),29420,862,30373,"0,0283804695",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,74","15,71"
"low bq, many samples",UPN2_053,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),23199,856,24141,"0,0354583489",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,61","16,01"
"low bq, many samples",UPN2_054,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),15416,576,16064,"0,0358565737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,66","15,67"
"low bq, many samples",UPN2_007,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),22685,548,23291,"0,0235284015",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,55","15,93"
"low bq, many samples",UPN2_008,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),35658,817,36574,"0,0223382731",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,65","15,57"
"low bq, low freq, many artifacts, many samples",UPN2_009,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),29253,609,29932,"0,0203461179",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,67","15,96"
"low bq, low freq, many artifacts, many samples",UPN2_010,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),17876,366,18294,"0,0200065595",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,63","15,58"
"low bq, low freq, many artifacts, many samples",UPN2_011,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),20057,442,20547,"0,0215116562",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,54","15,34"
"low bq, many samples",UPN2_055,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),24040,931,25035,"0,0371879369",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,57","16,21"
"low bq, many samples",UPN2_056,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),8552,355,8951,"0,0396603731",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,56","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_090,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),8118,84,8221,"0,0102177351",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,91","14,89"
"low bq, many samples",UPN2_057,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),18779,720,19574,"0,0367834883",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,5","15,77"
"low bq, many samples",UPN2_058,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),18618,795,19474,"0,0408236623",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,47","16,59"
"low bq, low freq, many artifacts, many samples",UPN2_059,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),2417,45,2466,"0,0182481752",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,23","14,64"
"low bq, many samples",UPN2_012,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),10967,265,11262,"0,0235304564",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,71","15,53"
"low bq, many samples",UPN2_060,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),4168,109,4293,"0,02539017",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,19","14,77"
"low bq, many samples",UPN2_040,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),14338,510,14896,"0,0342373792",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,48","15,64"
"low bq, many samples",UPN2_013,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),6016,137,6172,"0,0221970188",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,6","16,05"
"low bq, low freq, many artifacts, many samples",UPN2_093,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),5920,65,5997,"0,0108387527",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,9","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_061,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),5163,107,5297,"0,0202001133",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,27","15,79"
"low bq, low freq, many artifacts, many samples",UPN2_062,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),6948,139,7113,"0,0195416842",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,35","15,06"
"low bq, many samples",UPN2_063,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),4309,100,4422,"0,0226142017",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,13","14,96"
"low bq, many samples",UPN2_064,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),3942,92,4042,"0,0227610094",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,23","14,62"
"low bq, many samples",UPN2_065,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),1715,41,1764,"0,0232426304",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,2","14,8"
"low bq, many samples",UPN2_066,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),900,26,928,"0,0280172414",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,55","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_067,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),2016,41,2063,"0,0198739699",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,07","14,85"
"low bq, many samples",UPN2_068,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),2860,66,2934,"0,0224948875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,28","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_069,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),4329,93,4437,"0,0209601082",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,29","16,16"
"low bq, many samples",UPN2_070,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),2048,51,2106,"0,0242165242",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,26","14,27"
"low bq, many samples",UPN2_071,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),5157,144,5326,"0,0270371761",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,11","15,45"
"low bq, many samples",UPN2_072,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),6935,190,7144,"0,0265957447",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,1","15,32"
"low bq, many samples",UPN2_073,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),4136,100,4253,"0,0235128145",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,25","15,06"
"low bq, many samples",UPN2_074,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),1680,38,1722,"0,0220673635",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,15","15,11"
"low bq, many samples",UPN2_075,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),7112,168,7299,"0,0230168516",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,01","14,62"
"low bq, many samples",UPN2_076,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),3566,86,3666,"0,0234588107",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,46","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_077,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),3103,66,3176,"0,0207808564",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,41","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_078,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),4719,93,4828,"0,0192626346",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,29","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_079,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),2655,56,2713,"0,0206413564",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,04","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_080,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),5375,116,5509,"0,0210564531",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,21","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_081,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),7755,174,7957,"0,021867538",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,11","14,98"
"low bq, many samples",UPN2_082,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),3178,86,3273,"0,0262755881",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,21","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_083,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),5732,123,5880,"0,0209183673",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,18","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_084,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),5088,98,5202,"0,0188389081",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,25","15,77"
"low bq, many samples",UPN2_085,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),2780,66,2855,"0,023117338",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,14","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_086,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),1586,31,1622,"0,0191122072",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,32","15,29"
"low bq, many samples",UPN2_087,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),3575,88,3683,"0,023893565",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,12","15,41"
"low bq, low freq, many artifacts, many samples",UPN2_088,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),2947,65,3022,"0,0215089345",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,34","15,95"
"low bq, low freq, many artifacts, many samples",UPN2_096,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),12014,129,12185,"0,010586787",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,92","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_097,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),13405,145,13574,"0,0106821865",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,85","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_100,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),9226,101,9344,"0,0108090753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,95","15,51"
"low bq, low freq, many artifacts, many samples",UPN2_102,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),9229,97,9356,"0,0103676785",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,94","15,8"
"low bq, low freq, many artifacts, many samples",UPN2_109,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),14688,167,14903,"0,0112057975",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,86","15,04"
"low bq, low freq, many artifacts",UPN2_111,12,12043949,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp443Val/c.1328A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),11667,124,11821,"0,0104898063",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,51",Deleterious,1,Damaging,"31,9","14,73"
"low bq, low freq, many artifacts",UPN2_041,12,12043955,A,T,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln445Leu/c.1334A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),1277,28,1306,"0,02143951",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,32",Neutral,"0,246",Tolerated,"31,29","27,04"
"low bq, low freq, many artifacts",UPN2_044,12,12043968,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu449Asp/c.1347A>T|452|ETV6|protein_coding|CODING|ENST00000396373|8|T),4875,57,4956,"0,0115012107",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,05",Neutral,223,Tolerated,"32,64","26,37"
"low bq, many samples",UPN2_001,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),6902,446,7359,"0,0606060606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"29,73","14,42"
"low bq, many samples",UPN2_014,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),8671,417,9099,"0,045829212",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"28,86","14,15"
"low bq, many samples",UPN2_015,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),12430,584,13045,"0,0447681104",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"28,86","14,26"
"low bq, many samples",UPN2_016,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),6789,349,7147,"0,0488316776",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"28,95","14,1"
"low bq, many samples",UPN2_017,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),3297,141,3441,"0,0409764603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"28,93","14,49"
"low bq, many samples",UPN2_018,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),6581,313,6897,"0,0453820502",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"28,94","14,18"
"low bq, many samples",UPN2_019,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),7739,375,8131,"0,0461197885",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"29,01","14,36"
"low bq, many samples",UPN2_020,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),4556,225,4787,"0,0470022979",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"28,76","14,24"
"low bq, many samples",UPN2_021,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),6291,315,6624,"0,0475543478",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"28,98","14,16"
"low bq, many samples",UPN2_002,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),8367,518,8894,"0,0582415111",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"29,57","14,27"
"low bq, many samples",UPN2_003,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),1702,121,1824,"0,0663377193",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"29,54","14,32"
"low bq, many samples",UPN2_022,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),9914,456,10391,"0,0438841305",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"28,9","14,18"
"low bq, many samples",UPN2_023,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),10907,522,11445,"0,0456094364",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"28,97","14,2"
"low bq, many samples",UPN2_024,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),4007,183,4193,"0,0436441689",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"28,85","14,49"
"low bq, many samples",UPN2_025,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),12523,605,13136,"0,0460566382",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"29,01","14,44"
"low bq, many samples",UPN2_026,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),10859,517,11399,"0,0453548557",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"28,96","14,27"
"low bq, many samples",UPN2_004,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),525,38,568,"0,0669014085",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"30,11","14,34"
"low bq, many samples",UPN2_027,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),12724,635,13395,"0,0474057484",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"29,03","14,16"
"low bq, many samples",UPN2_089,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),7730,755,8491,"0,0889176775",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"29,03","14,74"
"low bq, many samples",UPN2_042,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),6177,555,6747,"0,0822587817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"28,42","14,31"
"low bq, many samples",UPN2_028,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),10100,466,10596,"0,0439788599",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"28,97","14,3"
"low bq, many samples",UPN2_043,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),6172,586,6776,"0,0864817001",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"28,49","14,46"
"low bq, many samples",UPN2_044,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),2466,260,2733,"0,0951335529",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"28,56","14,2"
"low bq, many samples",UPN2_029,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),9383,446,9844,"0,0453067859",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"28,99","14,2"
"low bq, many samples",UPN2_030,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),10670,544,11227,"0,0484546183",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"28,94","14,28"
"low bq, many samples",UPN2_031,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),6431,329,6773,"0,0485752252",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"28,96","14,19"
"low bq, many samples",UPN2_005,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),2628,173,2804,"0,0616975749",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"29,58","14,34"
"low bq, many samples",UPN2_045,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),4640,444,5095,"0,0871442591",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"28,52","14,32"
"low bq, many samples",UPN2_032,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),3863,180,4052,"0,0444225074",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"28,89","14,11"
"low bq, many samples",UPN2_046,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),9166,837,10017,"0,0835579515",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"28,34","14,39"
"low bq, many samples",UPN2_033,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),7924,421,8359,"0,0503648762",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"28,96","14,19"
"low bq, many samples",UPN2_034,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),2833,139,2981,"0,0466286481",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"28,91","14,05"
"low bq, many samples",UPN2_047,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),6222,610,6836,"0,0892334699",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"28,21","14,23"
"low bq, many samples",UPN2_048,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),787,80,869,"0,0920598389",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"28,52","14,25"
"low bq, many samples",UPN2_035,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),14284,709,15010,"0,0472351765",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"28,97","14,23"
"low bq, many samples",UPN2_036,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),9124,429,9567,"0,0448416431",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"28,98","14,3"
"low bq, many samples",UPN2_006,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),8743,553,9304,"0,0594368014",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"29,76","14,51"
"low bq, many samples",UPN2_049,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),6027,595,6634,"0,0896894784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"28,55","14,32"
"low bq, many samples",UPN2_050,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),7164,637,7816,"0,0814994882",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"28,36","14,62"
"low bq, many samples",UPN2_037,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),13239,581,13864,"0,0419070975",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"28,98","14,31"
"low bq, many samples",UPN2_051,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),10481,987,11501,"0,0858186245",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"28,29","14,45"
"low bq, many samples",UPN2_052,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),6808,637,7456,"0,0854345494",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"28,39","14,38"
"low bq, many samples",UPN2_038,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),16528,783,17329,"0,045184373",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"28,98","14,3"
"low bq, many samples",UPN2_039,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),13435,604,14088,"0,0428733674",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"29,01","14,16"
"low bq, many samples",UPN2_053,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),11233,1030,12294,"0,083780706",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"28,45","14,48"
"low bq, many samples",UPN2_054,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),7591,694,8295,"0,0836648583",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"28,3","14,34"
"low bq, many samples",UPN2_007,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),20233,1306,21566,"0,0605582862",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"29,74","14,4"
"low bq, many samples",UPN2_008,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),24678,1559,26285,"0,0593113943",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"29,86","14,32"
"low bq, many samples",UPN2_009,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),22393,1449,23891,"0,0606504541",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"29,86","14,35"
"low bq, many samples",UPN2_010,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),16065,1056,17153,"0,0615635749",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"29,76","14,4"
"low bq, many samples",UPN2_011,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),17635,1146,18810,"0,0609250399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"29,87","14,36"
"low bq, many samples",UPN2_055,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),10276,998,11304,"0,0882873319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"28,22","14,38"
"low bq, many samples",UPN2_056,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),999,96,1096,"0,0875912409",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"28,23","14,54"
"low bq, many samples",UPN2_090,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),5521,573,6105,"0,0938574939",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"29,16","14,65"
"low bq, many samples",UPN2_057,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),10394,1024,11442,"0,0894948436",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"28,42","14,38"
"low bq, many samples",UPN2_058,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),16291,1560,17884,"0,0872288079",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"28,38","14,48"
"low bq, many samples",UPN2_059,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),13291,1227,14552,"0,0843183068",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"30,29","14,62"
"low bq, many samples",UPN2_012,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),8811,575,9398,"0,0611832305",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"29,83","14,46"
"low bq, many samples",UPN2_060,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),14545,1235,15826,"0,0780361431",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"30,33","14,76"
"low bq, many samples",UPN2_040,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),12575,547,13163,"0,0415558763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"29,03","14,28"
"low bq, many samples",UPN2_013,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),6020,388,6420,"0,0604361371",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"29,69","14,55"
"low bq, many samples",UPN2_091,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),4381,454,4846,"0,0936855138",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"29,01","14,54"
"low bq, many samples",UPN2_092,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),3779,347,4137,"0,0838772057",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"28,92","14,82"
"low bq, many samples",UPN2_093,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),4040,397,4442,"0,0893741558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"29,04","14,61"
"low bq, many samples",UPN2_061,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),15554,1377,16968,"0,0811527581",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"30,37","14,68"
"low bq, many samples",UPN2_062,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),11229,932,12192,"0,0764435696",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"30,37","14,71"
"low bq, many samples",UPN2_063,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),13448,1186,14673,"0,080828733",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"30,27","14,8"
"low bq, many samples",UPN2_064,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),11837,1083,12950,"0,0836293436",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"30,3","14,56"
"low bq, many samples",UPN2_065,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),18096,1707,19859,"0,0859559897",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"30,3","14,88"
"low bq, many samples",UPN2_066,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),38751,3461,42331,"0,081760412",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"30,34","14,77"
"low bq, many samples",UPN2_067,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),38062,3501,41660,"0,084037446",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"30,32","14,76"
"low bq, many samples",UPN2_068,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),23803,2055,25932,"0,0792457196",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"30,21","14,8"
"low bq, many samples",UPN2_069,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),18444,1574,20072,"0,0784176963",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"30,28","14,79"
"low bq, many samples",UPN2_070,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),13419,1124,14590,"0,0770390679",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"30,31","14,63"
"low bq, many samples",UPN2_071,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),5651,484,6151,"0,0786863925",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"30,37","14,77"
"low bq, many samples",UPN2_072,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),7620,697,8345,"0,0835230677",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"30,27","14,81"
"low bq, many samples",UPN2_073,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),8390,749,9162,"0,0817507095",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"30,31","14,63"
"low bq, many samples",UPN2_074,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),14525,1228,15797,"0,077736279",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"30,19","14,67"
"low bq, many samples",UPN2_075,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),13721,1224,14982,"0,0816980376",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"30,31","14,69"
"low bq, many samples",UPN2_076,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),16321,1341,17707,"0,0757327611",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"30,22","14,76"
"low bq, many samples",UPN2_077,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),21415,1755,23242,"0,0755098529",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"30,32","14,74"
"low bq, many samples",UPN2_078,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),15130,1206,16377,"0,0736398608",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"30,22","14,82"
"low bq, many samples",UPN2_079,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),8578,732,9339,"0,078380983",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"30,3","14,81"
"low bq, many samples",UPN2_080,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),12882,1149,14103,"0,0814720272",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"30,32","14,71"
"low bq, many samples",UPN2_081,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),11084,1032,12130,"0,0850783182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"30,37","14,81"
"low bq, many samples",UPN2_082,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),29339,2592,32018,"0,0809544631",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"30,27","14,83"
"low bq, many samples",UPN2_083,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),18550,1566,20151,"0,0777132649",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"30,31","14,74"
"low bq, many samples",UPN2_084,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),28895,2481,31474,"0,0788269683",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"30,33","14,7"
"low bq, many samples",UPN2_085,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),36672,3198,39960,"0,08003003",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"30,33","14,69"
"low bq, many samples",UPN2_086,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),31246,2628,33962,"0,0773806018",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"30,27","14,83"
"low bq, many samples",UPN2_087,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),26038,2380,28504,"0,083497053",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"30,34","14,84"
"low bq, many samples",UPN2_088,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),19421,1727,21190,"0,0815007079",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"30,33","14,81"
"low bq, many samples",UPN2_094,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),4954,537,5501,"0,0976186148",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"29,14","14,6"
"low bq, many samples",UPN2_095,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),7093,643,7759,"0,0828715041",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"29,1","14,44"
"low bq, many samples",UPN2_096,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),5327,546,5882,"0,0928255695",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"29,26","14,69"
"low bq, many samples",UPN2_097,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),6701,667,7383,"0,0903426791",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"29,2","14,64"
"low bq, many samples",UPN2_098,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),5318,504,5838,"0,0863309353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"28,98","14,87"
"low bq, many samples",UPN2_099,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),3566,344,3922,"0,0877103519",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"29,09","14,36"
"low bq, many samples",UPN2_100,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),5116,530,5658,"0,0936726759",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"29,07","14,57"
"low bq, many samples",UPN2_101,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),6675,611,7298,"0,0837215676",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"29,15","14,78"
"low bq, many samples",UPN2_102,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),6553,584,7151,"0,0816668997",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"29,03","14,61"
"low bq, many samples",UPN2_103,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),6330,561,6914,"0,0811397165",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"29,01","14,6"
"low bq, many samples",UPN2_104,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),6787,690,7497,"0,0920368147",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"29,08","14,59"
"low bq, many samples",UPN2_105,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),5278,515,5803,"0,0887471997",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"29,19","14,53"
"low bq, many samples",UPN2_106,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),4739,479,5226,"0,0916570991",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"29,27","14,67"
"low bq, many samples",UPN2_107,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),10003,957,10976,"0,0871902332",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"29,07","14,49"
"low bq, many samples",UPN2_108,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),8184,800,9000,"0,0888888889",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"29,11","14,65"
"low bq, many samples",UPN2_109,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),8160,773,8947,"0,0863976752",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"29,11","14,68"
"low bq, many samples",UPN2_110,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),5863,596,6469,"0,0921317051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"29,34","14,6"
low bq,UPN2_111,12,25380178,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His94Asn/c.280C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),9373,923,10317,"0,0894639915",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,53",Neutral,779,Tolerated,"29,14","14,79"
"low freq, many artifacts",UPN2_006,12,25380180,A,G,missense_variant(MODERATE|MISSENSE|aTt/aCt|p.Ile93Thr/c.278T>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),9259,95,9374,"0,0101344143",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,0,Damaging,"33,35","33,76"
"low freq, many artifacts",UPN2_047,12,25380186,T,C,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu91Gly/c.272A>G|189|KRAS|protein_coding|CODING|ENST00000256078|3|C),6778,70,6866,"0,0101951646",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,3",Deleterious,"0,036",Damaging,"33,76","32,46"
"low freq, many artifacts",UPN2_044,12,25380205,T,C,missense_variant(MODERATE|MISSENSE|Aat/Gat|p.Asn85Asp/c.253A>G|189|KRAS|protein_coding|CODING|ENST00000256078|3|C),2711,30,2749,"0,0109130593",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,11",Deleterious,"0,051",Tolerated,"33,07","33,67"
"low bq, low freq, many artifacts",UPN2_071,12,25380228,C,A,missense_variant(MODERATE|MISSENSE|gGc/gTc|p.Gly77Val/c.230G>T|189|KRAS|protein_coding|CODING|ENST00000256078|3|A),6125,65,6207,"0,0104720477",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,91",Deleterious,0,Damaging,"29,52","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_042,12,25380230,C,A,missense_variant(MODERATE|MISSENSE|gaG/gaT|p.Glu76Asp/c.228G>T|189|KRAS|protein_coding|CODING|ENST00000256078|3|A),6688,80,6778,"0,0118028917",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,71",Deleterious,0,Damaging,"28,2","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_043,12,25380230,C,A,missense_variant(MODERATE|MISSENSE|gaG/gaT|p.Glu76Asp/c.228G>T|189|KRAS|protein_coding|CODING|ENST00000256078|3|A),6725,86,6835,"0,012582297",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,71",Deleterious,0,Damaging,"28,16","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_046,12,25380230,C,A,missense_variant(MODERATE|MISSENSE|gaG/gaT|p.Glu76Asp/c.228G>T|189|KRAS|protein_coding|CODING|ENST00000256078|3|A),9964,111,10085,"0,0110064452",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,71",Deleterious,0,Damaging,"28,23","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_047,12,25380230,C,A,missense_variant(MODERATE|MISSENSE|gaG/gaT|p.Glu76Asp/c.228G>T|189|KRAS|protein_coding|CODING|ENST00000256078|3|A),6784,82,6872,"0,0119324796",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,71",Deleterious,0,Damaging,"28,12","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_049,12,25380230,C,A,missense_variant(MODERATE|MISSENSE|gaG/gaT|p.Glu76Asp/c.228G>T|189|KRAS|protein_coding|CODING|ENST00000256078|3|A),6574,77,6670,"0,0115442279",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,71",Deleterious,0,Damaging,"28,1","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_050,12,25380230,C,A,missense_variant(MODERATE|MISSENSE|gaG/gaT|p.Glu76Asp/c.228G>T|189|KRAS|protein_coding|CODING|ENST00000256078|3|A),7756,88,7852,"0,0112073357",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,71",Deleterious,0,Damaging,"28,21","14,15"
"low bq, low freq, many artifacts, many samples",UPN2_051,12,25380230,C,A,missense_variant(MODERATE|MISSENSE|gaG/gaT|p.Glu76Asp/c.228G>T|189|KRAS|protein_coding|CODING|ENST00000256078|3|A),11424,126,11570,"0,0108902334",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,71",Deleterious,0,Damaging,"28,18","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_052,12,25380230,C,A,missense_variant(MODERATE|MISSENSE|gaG/gaT|p.Glu76Asp/c.228G>T|189|KRAS|protein_coding|CODING|ENST00000256078|3|A),7385,75,7496,"0,0100053362",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,71",Deleterious,0,Damaging,"28,27","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_053,12,25380230,C,A,missense_variant(MODERATE|MISSENSE|gaG/gaT|p.Glu76Asp/c.228G>T|189|KRAS|protein_coding|CODING|ENST00000256078|3|A),12234,130,12376,"0,0105042017",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,71",Deleterious,0,Damaging,"28,15","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_054,12,25380230,C,A,missense_variant(MODERATE|MISSENSE|gaG/gaT|p.Glu76Asp/c.228G>T|189|KRAS|protein_coding|CODING|ENST00000256078|3|A),8254,98,8367,"0,0117126808",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,71",Deleterious,0,Damaging,"28,13","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_055,12,25380230,C,A,missense_variant(MODERATE|MISSENSE|gaG/gaT|p.Glu76Asp/c.228G>T|189|KRAS|protein_coding|CODING|ENST00000256078|3|A),11204,131,11361,"0,0115306751",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,71",Deleterious,0,Damaging,"28,29","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_059,12,25380230,C,A,missense_variant(MODERATE|MISSENSE|gaG/gaT|p.Glu76Asp/c.228G>T|189|KRAS|protein_coding|CODING|ENST00000256078|3|A),14384,146,14547,"0,0100364336",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,71",Deleterious,0,Damaging,"28,48","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_060,12,25380230,C,A,missense_variant(MODERATE|MISSENSE|gaG/gaT|p.Glu76Asp/c.228G>T|189|KRAS|protein_coding|CODING|ENST00000256078|3|A),15680,169,15887,"0,0106376282",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,71",Deleterious,0,Damaging,"28,55","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_063,12,25380230,C,A,missense_variant(MODERATE|MISSENSE|gaG/gaT|p.Glu76Asp/c.228G>T|189|KRAS|protein_coding|CODING|ENST00000256078|3|A),14525,150,14697,"0,0102061645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,71",Deleterious,0,Damaging,"28,41","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_067,12,25380230,C,A,missense_variant(MODERATE|MISSENSE|gaG/gaT|p.Glu76Asp/c.228G>T|189|KRAS|protein_coding|CODING|ENST00000256078|3|A),41272,446,41795,"0,0106711329",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,71",Deleterious,0,Damaging,"28,38","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_068,12,25380230,C,A,missense_variant(MODERATE|MISSENSE|gaG/gaT|p.Glu76Asp/c.228G>T|189|KRAS|protein_coding|CODING|ENST00000256078|3|A),25673,283,26004,"0,0108829411",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,71",Deleterious,0,Damaging,"28,55","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_070,12,25380230,C,A,missense_variant(MODERATE|MISSENSE|gaG/gaT|p.Glu76Asp/c.228G>T|189|KRAS|protein_coding|CODING|ENST00000256078|3|A),14483,151,14657,"0,0103022447",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,71",Deleterious,0,Damaging,"28,56","15,56"
"low bq, low freq, many artifacts, many samples",UPN2_071,12,25380230,C,A,missense_variant(MODERATE|MISSENSE|gaG/gaT|p.Glu76Asp/c.228G>T|189|KRAS|protein_coding|CODING|ENST00000256078|3|A),6115,69,6193,"0,0111416115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,71",Deleterious,0,Damaging,"28,62","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_074,12,25380230,C,A,missense_variant(MODERATE|MISSENSE|gaG/gaT|p.Glu76Asp/c.228G>T|189|KRAS|protein_coding|CODING|ENST00000256078|3|A),15647,160,15838,"0,0101022856",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,71",Deleterious,0,Damaging,"28,51","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_077,12,25380230,C,A,missense_variant(MODERATE|MISSENSE|gaG/gaT|p.Glu76Asp/c.228G>T|189|KRAS|protein_coding|CODING|ENST00000256078|3|A),23075,238,23369,"0,0101844324",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,71",Deleterious,0,Damaging,"28,49","15,51"
"low bq, low freq, many artifacts, many samples",UPN2_079,12,25380230,C,A,missense_variant(MODERATE|MISSENSE|gaG/gaT|p.Glu76Asp/c.228G>T|189|KRAS|protein_coding|CODING|ENST00000256078|3|A),9266,97,9377,"0,0103444598",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,71",Deleterious,0,Damaging,"28,55","15,71"
"low bq, low freq, many artifacts, many samples",UPN2_081,12,25380230,C,A,missense_variant(MODERATE|MISSENSE|gaG/gaT|p.Glu76Asp/c.228G>T|189|KRAS|protein_coding|CODING|ENST00000256078|3|A),11966,141,12130,"0,0116240725",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,71",Deleterious,0,Damaging,"28,44","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_082,12,25380230,C,A,missense_variant(MODERATE|MISSENSE|gaG/gaT|p.Glu76Asp/c.228G>T|189|KRAS|protein_coding|CODING|ENST00000256078|3|A),31647,362,32042,"0,0112976718",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,71",Deleterious,0,Damaging,"28,48","15,45"
"low bq, low freq, many artifacts, many samples",UPN2_083,12,25380230,C,A,missense_variant(MODERATE|MISSENSE|gaG/gaT|p.Glu76Asp/c.228G>T|189|KRAS|protein_coding|CODING|ENST00000256078|3|A),19996,213,20248,"0,0105195575",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,71",Deleterious,0,Damaging,"28,65","15,78"
"low bq, low freq, many artifacts, many samples",UPN2_085,12,25380230,C,A,missense_variant(MODERATE|MISSENSE|gaG/gaT|p.Glu76Asp/c.228G>T|189|KRAS|protein_coding|CODING|ENST00000256078|3|A),39636,404,40130,"0,0100672813",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,71",Deleterious,0,Damaging,"28,49","14,88"
"low bq, low freq, many artifacts",UPN2_088,12,25380230,C,A,missense_variant(MODERATE|MISSENSE|gaG/gaT|p.Glu76Asp/c.228G>T|189|KRAS|protein_coding|CODING|ENST00000256078|3|A),21014,230,21289,"0,0108037014",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,71",Deleterious,0,Damaging,"28,37","15,05"
"low freq, many artifacts",UPN2_044,12,25380231,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu76Gly/c.227A>G|189|KRAS|protein_coding|CODING|ENST00000256078|3|C),2712,33,2747,"0,0120131052",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,93",Deleterious,"0,001",Damaging,"31,95","28,24"
inspected,UPN2_056,12,25380232,C,T,missense_variant(MODERATE|MISSENSE|Gag/Aag|p.Glu76Lys/c.226G>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),1037,56,1100,"0,0509090909",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,65",Deleterious,"0,091",Tolerated,"29,71","30,8"
"low freq, many artifacts",UPN2_044,12,25380241,T,A,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg73Trp/c.217A>T|189|KRAS|protein_coding|CODING|ENST00000256078|3|A),1340,23,1370,"0,0167883212",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,0,Damaging,"34,97","29,39"
"low freq, many artifacts",UPN2_016,12,25380256,T,A,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg68Trp/c.202A>T|189|KRAS|protein_coding|CODING|ENST00000256078|3|A),3603,42,3681,"0,011409943",0,0,0,0,0,1,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,9",Deleterious,0,Damaging,"35,4","35,71"
"low bq, low freq, many artifacts",UPN2_043,12,25380263,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser65Arg/c.195T>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),3360,35,3409,"0,0102669405",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,62",Deleterious,0,Damaging,"34,47","23,09"
"low freq, many artifacts, many samples",UPN2_001,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),6540,93,6641,"0,0140039151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,1,Damaging,"33,72","31,11"
"low freq, many artifacts, many samples",UPN2_014,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),9330,119,9463,"0,0125752932",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,1,Damaging,"33,6","31,06"
"low freq, many artifacts, many samples",UPN2_017,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),4029,56,4089,"0,01369528",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,1,Damaging,"33,42","30,64"
"low freq, many artifacts, many samples",UPN2_018,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),6724,78,6811,"0,0114520628",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,1,Damaging,"33,7","30,85"
"low freq, many artifacts, many samples",UPN2_019,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),8098,96,8205,"0,0117001828",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,1,Damaging,"33,69","31,23"
"low freq, many artifacts, many samples",UPN2_020,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),5644,84,5733,"0,0146520147",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,1,Damaging,"33,38","31,79"
"low freq, many artifacts, many samples",UPN2_021,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),6710,89,6809,"0,0130709355",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,1,Damaging,"33,6","31,35"
"low freq, many artifacts, many samples",UPN2_002,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),7865,95,7985,"0,0118973075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,1,Damaging,"33,73","31,08"
"low freq, many artifacts, many samples",UPN2_003,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),1649,26,1679,"0,015485408",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,1,Damaging,"33,55","30,62"
"low freq, many artifacts, many samples",UPN2_022,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),10132,116,10278,"0,0112862425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,1,Damaging,"33,66","31,25"
"many samples, low freq, no database",UPN2_023,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),10872,118,11008,"0,0107194767",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,"0,001",Damaging,"33,7","31,22"
"many samples, low freq, no database",UPN2_026,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),11735,136,11894,"0,0114343366",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,"0,001",Damaging,"33,56","31,82"
many samples,UPN2_004,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),1082,31,1116,"0,0277777778",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,1,Damaging,"32,68",32
"low freq, many artifacts, many samples",UPN2_027,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),13230,158,13418,"0,0117752273",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,1,Damaging,"33,63","31,79"
"low freq, many artifacts, many samples",UPN2_028,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),10031,102,10149,"0,0100502513",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,1,Damaging,"33,72","31,4"
"low freq, many artifacts, many samples",UPN2_029,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),10348,134,10496,"0,0127667683",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,1,Damaging,"33,52","31,22"
"low freq, many artifacts, many samples",UPN2_005,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),2456,40,2503,"0,015980823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,1,Damaging,"33,79","30,55"
"low freq, many artifacts, many samples",UPN2_032,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),4049,42,4102,"0,0102389078",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,1,Damaging,"33,67",32
"low freq, many artifacts, many samples",UPN2_048,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),8068,91,8170,"0,0111383109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,1,Damaging,"31,91","31,76"
"low freq, many artifacts, many samples",UPN2_035,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),15479,187,15693,"0,011916141",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,1,Damaging,"33,55","31,15"
"low freq, many artifacts, many samples",UPN2_036,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),9142,100,9256,"0,0108038029",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,1,Damaging,"33,66","31,64"
"low freq, many artifacts, many samples",UPN2_006,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),9115,159,9281,"0,0171317746",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,1,Damaging,"33,53","31,56"
"low freq, many artifacts, many samples",UPN2_037,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),13995,146,14156,"0,0103136479",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,1,Damaging,"33,63","31,55"
"many samples, low freq, no database",UPN2_038,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),17396,201,17641,"0,0113939119",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,"0,001",Damaging,"33,6","31,34"
"low freq, many artifacts, many samples",UPN2_039,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),13474,166,13658,"0,0121540489",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,1,Damaging,"33,73","31,23"
"low freq, many artifacts, many samples",UPN2_007,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),19113,210,19363,"0,0108454268",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,1,Damaging,"33,71","31,34"
"low freq, many artifacts, many samples",UPN2_008,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),24569,267,24871,"0,0107353946",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,1,Damaging,"33,69","31,42"
"many samples, low freq, no database",UPN2_011,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),17224,241,17485,"0,0137832428",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,"0,001",Damaging,"33,7","31,43"
"many samples, low freq, no database",UPN2_059,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),22110,300,22448,"0,0133642195",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,"0,001",Damaging,"32,82","31,27"
"low freq, many artifacts, many samples",UPN2_012,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),8592,100,8707,"0,0114850121",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,1,Damaging,"33,61","31,35"
"low freq, many artifacts, many samples",UPN2_060,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),15894,255,16185,"0,015755329",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,1,Damaging,"33,39","31,31"
"low freq, many artifacts, many samples",UPN2_040,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),14419,230,14664,"0,0156846699",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,1,Damaging,"33,51","31,39"
"low freq, many artifacts, many samples",UPN2_013,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),5251,65,5324,"0,0122088655",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,1,Damaging,"33,91","30,94"
"low freq, many artifacts, many samples",UPN2_061,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),16942,260,17232,"0,015088208",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,1,Damaging,"33,41","31,36"
"many samples, low freq, no database",UPN2_062,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),13719,265,14017,"0,0189056146",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,"0,001",Damaging,"33,18","31,4"
"low freq, many artifacts, many samples",UPN2_063,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),15050,265,15343,"0,01727172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,1,Damaging,"33,34","31,22"
"many samples, low freq, no database",UPN2_064,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),17702,389,18133,"0,0214526002",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,"0,001",Damaging,"32,95","31,1"
"many samples, low freq, no database",UPN2_065,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),20289,225,20544,"0,0109521028",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,"0,001",Damaging,"33,29","30,6"
"many samples, low freq, no database",UPN2_066,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),35962,402,36442,"0,0110312277",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,"0,001",Damaging,"33,69","31,17"
"many samples, low freq, no database",UPN2_067,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),36111,395,36583,"0,0107973649",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,"0,001",Damaging,"33,65","30,9"
"low freq, many artifacts, many samples",UPN2_068,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),23194,235,23483,"0,0100072393",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,1,Damaging,"33,59","30,8"
"many samples, low freq, no database",UPN2_069,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),20339,304,20676,"0,0147030373",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,"0,001",Damaging,"33,39","31,01"
"low freq, many artifacts, many samples",UPN2_070,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),14283,201,14499,"0,013863025",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,1,Damaging,"33,44","31,12"
"low freq, many artifacts, many samples",UPN2_071,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),8318,170,8500,"0,02",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,1,Damaging,"32,93","31,14"
"low freq, many artifacts, many samples",UPN2_072,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),11466,244,11728,"0,0208049113",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,1,Damaging,"32,93","31,32"
"many samples, low freq, no database",UPN2_073,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),11415,196,11638,"0,0168413817",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,"0,001",Damaging,"33,09","31,13"
"many samples, low freq, no database",UPN2_074,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),14543,207,14776,"0,0140092041",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,"0,001",Damaging,"33,52","31,45"
"many samples, low freq, no database",UPN2_075,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),16352,267,16645,"0,0160408531",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,"0,001",Damaging,"33,21","31,33"
"many samples, low freq, no database",UPN2_076,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),17241,255,17520,"0,0145547945",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,"0,001",Damaging,"33,48","31,11"
"many samples, low freq, no database",UPN2_077,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),21280,275,21596,"0,0127338396",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,"0,001",Damaging,"33,57","31,07"
"many samples, low freq, no database",UPN2_078,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),15906,258,16210,"0,0159161012",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,"0,001",Damaging,"33,49","31,02"
"low freq, many artifacts, many samples",UPN2_079,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),9946,171,10131,"0,0168788866",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,1,Damaging,"33,29","31,63"
"low freq, many artifacts, many samples",UPN2_080,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),15431,273,15730,"0,0173553719",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,1,Damaging,"33,23","31,29"
"low freq, many artifacts, many samples",UPN2_081,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),18006,288,18341,"0,0157025244",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,1,Damaging,"32,82","30,78"
"low freq, many artifacts, many samples",UPN2_082,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),29533,305,29894,"0,0102027163",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,1,Damaging,"33,53","30,83"
"many samples, low freq, no database",UPN2_083,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),19831,344,20212,"0,0170195923",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,"0,001",Damaging,"33,45","30,87"
"low freq, many artifacts, many samples",UPN2_084,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),27195,298,27583,"0,0108037559",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,1,Damaging,"33,66","30,81"
"low freq, many artifacts",UPN2_087,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),27110,345,27505,"0,012543174",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,1,Damaging,"33,48","30,99"
"many samples, low freq, no database",UPN2_088,12,25380274,C,G,missense_variant(MODERATE|MISSENSE|Gag/Cag|p.Glu62Gln/c.184G>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),19326,242,19599,"0,0123475688",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,78",Deleterious,"0,001",Damaging,"33,55","31,11"
"low freq, many artifacts",UPN2_044,12,25380287,G,T,missense_variant(MODERATE|MISSENSE|gaC/gaA|p.Asp57Glu/c.171C>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),2481,34,2524,"0,0134706815",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,78",Deleterious,1,Damaging,"35,08",31
"low freq, many artifacts",UPN2_048,12,25380297,TC,T,frameshift_variant(HIGH||gat/|p.Asp54fs/c.160delG|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),8078,106,8207,"0,0129158036",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,12",NA
"low freq, many artifacts",UPN2_044,12,25380298,C,T,missense_variant(MODERATE|MISSENSE|Gat/Aat|p.Asp54Asn/c.160G>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),2491,27,2525,"0,0106930693",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,63",Deleterious,9,Damaging,"35,22",36
"low freq, many artifacts",UPN2_044,12,25380299,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu53Phe/c.159G>T|189|KRAS|protein_coding|CODING|ENST00000256078|3|A),2476,46,2525,"0,0182178218",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,61",Deleterious,"0,001",Damaging,"34,93","33,91"
"low freq, many artifacts",UPN2_044,12,25380313,CT,C,frameshift_variant(HIGH||gga/|p.Glu49fs/c.144delA|189|KRAS|protein_coding|CODING|ENST00000256078|3|C),2478,31,2525,"0,0122772277",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,32",NA
"low freq, many artifacts",UPN2_069,12,25380327,A,T,missense_variant(MODERATE|MISSENSE|gTa/gAa|p.Val44Glu/c.131T>A|189|KRAS|protein_coding|CODING|ENST00000256078|3|T),20345,243,20723,"0,0117261014",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,38",Deleterious,"0,001",Damaging,"33,42","31,67"
"low freq, many artifacts",UPN2_006,12,25380329,T,G,missense_variant(MODERATE|MISSENSE|caA/caC|p.Gln43His/c.129A>C|189|KRAS|protein_coding|CODING|ENST00000256078|3|G),4603,49,4691,"0,010445534",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,39",Deleterious,6,Damaging,"34,95","31,63"
"low freq, many artifacts",UPN2_056,12,25398270,T,C,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser17Gly/c.49A>G|189|KRAS|protein_coding|CODING|ENST00000256078|2|C),1652,34,1686,"0,0201660735",0,0,0,0,1,1,0,1,3,NO,NO,COSM540,pancreas,1,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,"0,001",Damaging,"33,71","31,82"
"low freq, many artifacts",UPN2_006,12,25398287,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala11Asp/c.32C>A|189|KRAS|protein_coding|CODING|ENST00000256078|2|T),9714,103,9833,"0,0104749314",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,36",Neutral,305,Tolerated,"33,85","29,18"
"low bq, low freq, many artifacts",UPN2_049,12,25398299,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val7Glu/c.20T>A|189|KRAS|protein_coding|CODING|ENST00000256078|2|T),12628,166,12829,"0,0129394341",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,67",Deleterious,0,Damaging,"33,44","28,07"
"low freq, many artifacts",UPN2_056,12,25398316,C,T,start_lost(HIGH|MISSENSE|atG/atA|p.Met1?/c.3G>A|189|KRAS|protein_coding|CODING|ENST00000256078|2|T),1654,29,1688,"0,0171800948",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,48",Neutral,"0,013",Damaging,"31,64","32,34"
"low bq, low freq, many artifacts",UPN2_044,12,25398327,G,T,splice_region_variant(LOW|||c.-9C>A|189|KRAS|protein_coding|CODING|ENST00000256078|2|T),2879,34,2919,"0,0116478246",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,07","20,44"
"low bq, low freq, many artifacts, many samples",UPN2_063,12,25398328,G,T,splice_region_variant(LOW|||c.-10C>A|189|KRAS|protein_coding|CODING|ENST00000256078|2|T),14568,164,14753,"0,0111163831",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,23","14,08"
"low bq, low freq, many artifacts, many samples",UPN2_070,12,25398328,G,T,splice_region_variant(LOW|||c.-10C>A|189|KRAS|protein_coding|CODING|ENST00000256078|2|T),13037,137,13186,"0,0103898074",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,21","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_077,12,25398328,G,T,splice_region_variant(LOW|||c.-10C>A|189|KRAS|protein_coding|CODING|ENST00000256078|2|T),19053,223,19317,"0,0115442356",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,29","14,49"
"low bq, low freq, many artifacts",UPN2_082,12,25398328,G,T,splice_region_variant(LOW|||c.-10C>A|189|KRAS|protein_coding|CODING|ENST00000256078|2|T),24444,251,24740,"0,0101455133",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,37","14,59"
"low freq, many artifacts",UPN2_048,13,28592653,C,T,missense_variant(MODERATE|MISSENSE|gGa/gAa|p.Gly831Glu/c.2492G>A|993|FLT3|protein_coding|CODING|ENST00000241453|20|T),6619,116,6767,"0,0171420127",0,0,0,0,1,1,0,1,3,NO,NO,COSM25248,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-7,3",Deleterious,0,Damaging,"32,62","33,13"
"low freq, many artifacts",UPN2_044,13,28592686,G,A,missense_variant(MODERATE|MISSENSE|aCc/aTc|p.Thr820Ile/c.2459C>T|993|FLT3|protein_coding|CODING|ENST00000241453|20|A),12298,154,12469,"0,0123506296",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,0,Damaging,"34,16","34,73"
"low bq, low freq, many artifacts, many samples",UPN2_059,13,28592722,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val808Gly/c.2423T>G|993|FLT3|protein_coding|CODING|ENST00000241453|20|C),56333,642,57412,"0,0111823312",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,38",Deleterious,0,Damaging,"31,01","16,71"
"low bq, low freq, many artifacts, many samples",UPN2_060,13,28592722,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val808Gly/c.2423T>G|993|FLT3|protein_coding|CODING|ENST00000241453|20|C),44813,517,45602,"0,0113372221",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,38",Deleterious,0,Damaging,31,"17,05"
"low bq, low freq, many artifacts, many samples",UPN2_061,13,28592722,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val808Gly/c.2423T>G|993|FLT3|protein_coding|CODING|ENST00000241453|20|C),50879,606,51814,"0,0116956807",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,38",Deleterious,0,Damaging,31,"16,76"
"low bq, low freq, many artifacts, many samples",UPN2_062,13,28592722,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val808Gly/c.2423T>G|993|FLT3|protein_coding|CODING|ENST00000241453|20|C),48540,627,49477,"0,0126725549",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,38",Deleterious,0,Damaging,"30,91","16,99"
"low bq, low freq, many artifacts, many samples",UPN2_063,13,28592722,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val808Gly/c.2423T>G|993|FLT3|protein_coding|CODING|ENST00000241453|20|C),53368,649,54464,"0,0119161281",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,38",Deleterious,0,Damaging,"30,98","17,37"
"low bq, low freq, many artifacts, many samples",UPN2_064,13,28592722,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val808Gly/c.2423T>G|993|FLT3|protein_coding|CODING|ENST00000241453|20|C),54599,648,55566,"0,0116618076",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,38",Deleterious,0,Damaging,"30,99","16,66"
"low bq, low freq, many artifacts, many samples",UPN2_065,13,28592722,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val808Gly/c.2423T>G|993|FLT3|protein_coding|CODING|ENST00000241453|20|C),64585,791,65800,"0,0120212766",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,38",Deleterious,0,Damaging,"31,02","17,01"
"low bq, low freq, many artifacts, many samples",UPN2_066,13,28592722,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val808Gly/c.2423T>G|993|FLT3|protein_coding|CODING|ENST00000241453|20|C),94287,1044,96008,"0,0108740938",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,38",Deleterious,0,Damaging,"31,04","16,53"
"low bq, low freq, many artifacts, many samples",UPN2_067,13,28592722,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val808Gly/c.2423T>G|993|FLT3|protein_coding|CODING|ENST00000241453|20|C),90280,972,91814,"0,0105866208",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,38",Deleterious,0,Damaging,"31,12","17,06"
"low bq, low freq, many artifacts, many samples",UPN2_068,13,28592722,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val808Gly/c.2423T>G|993|FLT3|protein_coding|CODING|ENST00000241453|20|C),58062,764,59192,"0,0129071496",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,38",Deleterious,0,Damaging,"30,89","16,65"
"low bq, low freq, many artifacts, many samples",UPN2_069,13,28592722,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val808Gly/c.2423T>G|993|FLT3|protein_coding|CODING|ENST00000241453|20|C),52635,686,53632,"0,0127908711",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,38",Deleterious,0,Damaging,"30,96","16,55"
"low bq, low freq, many artifacts, many samples",UPN2_070,13,28592722,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val808Gly/c.2423T>G|993|FLT3|protein_coding|CODING|ENST00000241453|20|C),38163,496,38902,"0,0127499871",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,38",Deleterious,0,Damaging,"30,9","16,58"
"low bq, low freq, many artifacts, many samples",UPN2_071,13,28592722,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val808Gly/c.2423T>G|993|FLT3|protein_coding|CODING|ENST00000241453|20|C),29849,375,30433,"0,0123221503",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,38",Deleterious,0,Damaging,"30,96","16,85"
"low bq, low freq, many artifacts, many samples",UPN2_072,13,28592722,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val808Gly/c.2423T>G|993|FLT3|protein_coding|CODING|ENST00000241453|20|C),40331,463,41058,"0,0112767305",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,38",Deleterious,0,Damaging,"30,98","16,9"
"low bq, low freq, many artifacts, many samples",UPN2_073,13,28592722,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val808Gly/c.2423T>G|993|FLT3|protein_coding|CODING|ENST00000241453|20|C),30706,332,31236,"0,0106287617",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,38",Deleterious,0,Damaging,"31,05","16,6"
"low bq, low freq, many artifacts, many samples",UPN2_074,13,28592722,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val808Gly/c.2423T>G|993|FLT3|protein_coding|CODING|ENST00000241453|20|C),37956,430,38659,"0,0111228951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,38",Deleterious,0,Damaging,"31,08","16,69"
"low bq, low freq, many artifacts, many samples",UPN2_076,13,28592722,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val808Gly/c.2423T>G|993|FLT3|protein_coding|CODING|ENST00000241453|20|C),43449,562,44315,"0,0126819361",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,38",Deleterious,0,Damaging,"30,91",17
"low bq, low freq, many artifacts, many samples",UPN2_077,13,28592722,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val808Gly/c.2423T>G|993|FLT3|protein_coding|CODING|ENST00000241453|20|C),52902,644,53886,"0,0119511561",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,38",Deleterious,0,Damaging,31,"16,78"
"low bq, low freq, many artifacts, many samples",UPN2_078,13,28592722,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val808Gly/c.2423T>G|993|FLT3|protein_coding|CODING|ENST00000241453|20|C),38095,492,38837,"0,0126683317",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,38",Deleterious,0,Damaging,"30,9","16,57"
"low bq, low freq, many artifacts, many samples",UPN2_079,13,28592722,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val808Gly/c.2423T>G|993|FLT3|protein_coding|CODING|ENST00000241453|20|C),26901,298,27395,"0,0108778974",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,38",Deleterious,0,Damaging,"31,03","16,69"
"low bq, low freq, many artifacts, many samples",UPN2_080,13,28592722,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val808Gly/c.2423T>G|993|FLT3|protein_coding|CODING|ENST00000241453|20|C),41220,508,41980,"0,0121010005",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,38",Deleterious,0,Damaging,"31,05",17
"low bq, low freq, many artifacts, many samples",UPN2_081,13,28592722,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val808Gly/c.2423T>G|993|FLT3|protein_coding|CODING|ENST00000241453|20|C),42958,501,43736,"0,0114550942",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,38",Deleterious,0,Damaging,"31,05","16,91"
"low bq, low freq, many artifacts, many samples",UPN2_082,13,28592722,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val808Gly/c.2423T>G|993|FLT3|protein_coding|CODING|ENST00000241453|20|C),69346,802,70588,"0,0113617045",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,38",Deleterious,0,Damaging,"31,02","16,75"
"low bq, low freq, many artifacts, many samples",UPN2_083,13,28592722,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val808Gly/c.2423T>G|993|FLT3|protein_coding|CODING|ENST00000241453|20|C),52383,713,53485,"0,0133308404",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,38",Deleterious,0,Damaging,"30,9","17,23"
"low bq, low freq, many artifacts, many samples",UPN2_084,13,28592722,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val808Gly/c.2423T>G|993|FLT3|protein_coding|CODING|ENST00000241453|20|C),71778,938,73236,"0,0128079087",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,38",Deleterious,0,Damaging,"30,91","17,07"
"low bq, low freq, many artifacts, many samples",UPN2_085,13,28592722,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val808Gly/c.2423T>G|993|FLT3|protein_coding|CODING|ENST00000241453|20|C),90371,1117,92145,"0,0121221987",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,38",Deleterious,0,Damaging,"30,99","16,88"
"low bq, low freq, many artifacts, many samples",UPN2_086,13,28592722,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val808Gly/c.2423T>G|993|FLT3|protein_coding|CODING|ENST00000241453|20|C),87884,1105,89622,"0,0123295619",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,38",Deleterious,0,Damaging,"30,93","17,18"
"low bq, low freq, many artifacts, many samples",UPN2_087,13,28592722,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val808Gly/c.2423T>G|993|FLT3|protein_coding|CODING|ENST00000241453|20|C),63055,776,64242,"0,0120793251",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,38",Deleterious,0,Damaging,"30,95","17,04"
"low bq, low freq, many artifacts",UPN2_088,13,28592722,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val808Gly/c.2423T>G|993|FLT3|protein_coding|CODING|ENST00000241453|20|C),51988,561,52841,"0,0106167559",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,38",Deleterious,0,Damaging,"31,11","16,82"
"low bq, low freq, many artifacts",UPN2_044,13,28592722,A,T,missense_variant(MODERATE|MISSENSE|gTt/gAt|p.Val808Asp/c.2423T>A|993|FLT3|protein_coding|CODING|ENST00000241453|20|T),12253,150,12452,"0,0120462576",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,67",Deleterious,0,Damaging,"32,83","27,45"
"low freq, many artifacts",UPN2_041,15,90631829,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His175Arg/c.524A>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),2548,36,2587,"0,0139157325",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,92",Deleterious,"0,005",Damaging,"35,47","35,56"
"low freq, many artifacts",UPN2_044,15,90631833,C,T,missense_variant(MODERATE|MISSENSE|Gcc/Acc|p.Ala174Thr/c.520G>A|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),6682,74,6765,"0,0109386548",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,79",Deleterious,0,Damaging,"35,42","35,43"
"low bq, low freq, many artifacts, many samples",UPN2_059,15,90631871,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val161Gly/c.482T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),7004,84,7114,"0,0118077031",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,67",Deleterious,0,Damaging,"28,25","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_060,15,90631871,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val161Gly/c.482T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),9641,130,9826,"0,0132302056",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,67",Deleterious,0,Damaging,"28,33","16,24"
"low bq, low freq, many artifacts, many samples",UPN2_061,15,90631871,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val161Gly/c.482T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),13009,241,13301,"0,0181189384",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,67",Deleterious,0,Damaging,"27,82","15,42"
"low bq, low freq, many artifacts, many samples",UPN2_062,15,90631871,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val161Gly/c.482T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),14245,232,14537,"0,0159592763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,67",Deleterious,0,Damaging,"27,59","15,59"
"low bq, low freq, many artifacts, many samples",UPN2_063,15,90631871,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val161Gly/c.482T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),13470,215,13759,"0,0156261356",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,67",Deleterious,0,Damaging,"28,13","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_064,15,90631871,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val161Gly/c.482T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),13071,175,13296,"0,0131618532",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,67",Deleterious,0,Damaging,"27,94","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_065,15,90631871,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val161Gly/c.482T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),6618,95,6747,"0,014080332",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,67",Deleterious,0,Damaging,"27,92","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_066,15,90631871,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val161Gly/c.482T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),5763,78,5867,"0,0132946992",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,67",Deleterious,0,Damaging,"28,37","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_067,15,90631871,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val161Gly/c.482T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),6496,82,6606,"0,0124129579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,67",Deleterious,0,Damaging,"28,83","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_068,15,90631871,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val161Gly/c.482T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),8267,135,8460,"0,0159574468",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,67",Deleterious,0,Damaging,"27,39","15,39"
"low bq, low freq, many artifacts, many samples",UPN2_069,15,90631871,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val161Gly/c.482T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),11227,175,11435,"0,0153038916",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,67",Deleterious,0,Damaging,"27,74","15,54"
"low bq, low freq, many artifacts, many samples",UPN2_070,15,90631871,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val161Gly/c.482T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),7338,134,7505,"0,0178547635",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,67",Deleterious,0,Damaging,"27,59","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_071,15,90631871,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val161Gly/c.482T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),8781,144,8974,"0,0160463561",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,67",Deleterious,0,Damaging,"27,98","15,46"
"low bq, low freq, many artifacts, many samples",UPN2_072,15,90631871,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val161Gly/c.482T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),12125,189,12345,"0,015309842",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,67",Deleterious,0,Damaging,"27,98","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_073,15,90631871,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val161Gly/c.482T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),7744,108,7885,"0,0136968928",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,67",Deleterious,0,Damaging,"28,15","15,89"
"low bq, low freq, many artifacts, many samples",UPN2_074,15,90631871,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val161Gly/c.482T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),4457,49,4526,"0,0108263367",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,67",Deleterious,0,Damaging,"28,28","15,59"
"low bq, low freq, many artifacts, many samples",UPN2_075,15,90631871,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val161Gly/c.482T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),13083,178,13311,"0,0133723988",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,67",Deleterious,0,Damaging,"28,7","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_076,15,90631871,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val161Gly/c.482T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),8478,135,8664,"0,0155817175",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,67",Deleterious,0,Damaging,"27,76","15,76"
"low bq, low freq, many artifacts, many samples",UPN2_077,15,90631871,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val161Gly/c.482T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),8502,140,8677,"0,0161346087",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,67",Deleterious,0,Damaging,"27,73","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_078,15,90631871,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val161Gly/c.482T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),10653,196,10886,"0,0180047768",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,67",Deleterious,0,Damaging,"27,57","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_079,15,90631871,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val161Gly/c.482T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),6589,95,6702,"0,0141748732",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,67",Deleterious,0,Damaging,"28,2","15,85"
"low bq, low freq, many artifacts, many samples",UPN2_080,15,90631871,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val161Gly/c.482T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),12083,201,12341,"0,0162871728",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,67",Deleterious,0,Damaging,"27,79","15,56"
"low bq, low freq, many artifacts, many samples",UPN2_081,15,90631871,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val161Gly/c.482T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),14447,235,14735,"0,0159484221",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,67",Deleterious,0,Damaging,"28,1","15,49"
"low bq, low freq, many artifacts, many samples",UPN2_082,15,90631871,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val161Gly/c.482T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),8214,141,8395,"0,0167957117",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,67",Deleterious,0,Damaging,"28,28","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_083,15,90631871,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val161Gly/c.482T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),11997,195,12237,"0,0159352783",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,67",Deleterious,0,Damaging,"27,45","15,57"
"low bq, low freq, many artifacts, many samples",UPN2_084,15,90631871,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val161Gly/c.482T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),12422,228,12698,"0,0179555836",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,67",Deleterious,0,Damaging,"27,5",15
"low bq, low freq, many artifacts, many samples",UPN2_085,15,90631871,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val161Gly/c.482T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),6505,105,6631,"0,0158347157",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,67",Deleterious,0,Damaging,"27,67","16,28"
"low bq, low freq, many artifacts, many samples",UPN2_086,15,90631871,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val161Gly/c.482T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),4215,79,4307,"0,0183422336",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,67",Deleterious,0,Damaging,"27,52",16
"low bq, low freq, many artifacts, many samples",UPN2_087,15,90631871,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val161Gly/c.482T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),11224,173,11437,"0,0151263443",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,67",Deleterious,0,Damaging,"27,84","15,64"
"low bq, low freq, many artifacts",UPN2_088,15,90631871,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val161Gly/c.482T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),8636,102,8767,"0,0116345386",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,67",Deleterious,0,Damaging,"28,66","15,39"
"low bq, low freq, many artifacts, many samples",UPN2_062,15,90631884,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile157Leu/c.469A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),14310,170,14533,"0,011697516",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,9",Neutral,35,Damaging,"30,09","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_063,15,90631884,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile157Leu/c.469A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),13563,153,13757,"0,0111216108",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,9",Neutral,35,Damaging,"30,36","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_068,15,90631884,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile157Leu/c.469A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),8319,112,8457,"0,013243467",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,9",Neutral,35,Damaging,"30,01","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_069,15,90631884,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile157Leu/c.469A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),11273,120,11431,"0,0104977692",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,9",Neutral,35,Damaging,"30,19","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_070,15,90631884,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile157Leu/c.469A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),7394,80,7502,"0,010663823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,9",Neutral,35,Damaging,"30,15","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_072,15,90631884,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile157Leu/c.469A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),12154,140,12344,"0,0113415424",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,9",Neutral,35,Damaging,"30,19","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_074,15,90631884,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile157Leu/c.469A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),4461,50,4525,"0,0110497238",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,9",Neutral,35,Damaging,"30,52","15,46"
"low bq, low freq, many artifacts, many samples",UPN2_076,15,90631884,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile157Leu/c.469A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),8536,96,8663,"0,0110816115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,9",Neutral,35,Damaging,30,"15,33"
"low bq, low freq, many artifacts, many samples",UPN2_078,15,90631884,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile157Leu/c.469A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),10730,118,10884,"0,0108416024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,9",Neutral,35,Damaging,"30,18","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_079,15,90631884,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile157Leu/c.469A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),6579,95,6701,"0,0141769885",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,9",Neutral,35,Damaging,"30,4","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_081,15,90631884,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile157Leu/c.469A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),14528,148,14733,"0,0100454761",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,9",Neutral,35,Damaging,"30,37","15,46"
"low bq, low freq, many artifacts, many samples",UPN2_083,15,90631884,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile157Leu/c.469A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),12039,148,12235,"0,0120964446",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,9",Neutral,35,Damaging,"30,05","15,61"
"low bq, low freq, many artifacts, many samples",UPN2_084,15,90631884,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile157Leu/c.469A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),12479,169,12695,"0,0133123277",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,9",Neutral,35,Damaging,"29,85","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_085,15,90631884,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile157Leu/c.469A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),6541,69,6629,"0,0104088098",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,9",Neutral,35,Damaging,"30,19","14,84"
"low bq, low freq, many artifacts",UPN2_086,15,90631884,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile157Leu/c.469A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),4237,56,4305,"0,0130081301",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,9",Neutral,35,Damaging,"29,97","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_059,15,90631886,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn156Thr/c.467A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),6954,105,7114,"0,0147596289",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,34,Damaging,"30,46","16,59"
"low bq, low freq, many artifacts, many samples",UPN2_060,15,90631886,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn156Thr/c.467A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),9657,120,9824,"0,0122149837",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,34,Damaging,"30,55","17,27"
"low bq, low freq, many artifacts, many samples",UPN2_061,15,90631886,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn156Thr/c.467A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),13048,189,13299,"0,0142115949",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,34,Damaging,"30,18","17,69"
"low bq, low freq, many artifacts, many samples",UPN2_062,15,90631886,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn156Thr/c.467A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),14257,208,14533,"0,0143122549",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,34,Damaging,"30,1","17,15"
"low bq, low freq, many artifacts, many samples",UPN2_063,15,90631886,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn156Thr/c.467A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),13501,168,13757,"0,0122119648",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,34,Damaging,"30,27","17,28"
"low bq, low freq, many artifacts, many samples",UPN2_064,15,90631886,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn156Thr/c.467A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),13049,153,13290,"0,0115124153",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,34,Damaging,"30,25","16,31"
"low bq, low freq, many artifacts, many samples",UPN2_065,15,90631886,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn156Thr/c.467A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),6615,96,6746,"0,0142306552",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,34,Damaging,"30,56","17,25"
"low bq, low freq, many artifacts, many samples",UPN2_066,15,90631886,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn156Thr/c.467A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),5761,69,5864,"0,0117667121",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,34,Damaging,"30,71","18,64"
"low bq, low freq, many artifacts, many samples",UPN2_067,15,90631886,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn156Thr/c.467A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),6493,80,6605,"0,0121120363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,34,Damaging,"30,67","18,5"
"low bq, low freq, many artifacts, many samples",UPN2_068,15,90631886,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn156Thr/c.467A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),8289,125,8457,"0,0147806551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,34,Damaging,"30,07","17,02"
"low bq, low freq, many artifacts, many samples",UPN2_069,15,90631886,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn156Thr/c.467A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),11228,146,11431,"0,0127722859",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,34,Damaging,"30,21","16,58"
"low bq, low freq, many artifacts, many samples",UPN2_070,15,90631886,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn156Thr/c.467A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),7332,122,7501,"0,0162644981",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,34,Damaging,"30,05","16,89"
"low bq, low freq, many artifacts, many samples",UPN2_071,15,90631886,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn156Thr/c.467A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),8794,118,8972,"0,0131520285",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,34,Damaging,"30,33","18,97"
"low bq, low freq, many artifacts, many samples",UPN2_072,15,90631886,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn156Thr/c.467A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),12122,170,12343,"0,0137729887",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,34,Damaging,"30,21","16,62"
"low bq, low freq, many artifacts, many samples",UPN2_073,15,90631886,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn156Thr/c.467A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),7754,83,7882,"0,0105303223",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,34,Damaging,"30,51","17,7"
"low bq, low freq, many artifacts, many samples",UPN2_074,15,90631886,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn156Thr/c.467A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),4449,52,4525,"0,0114917127",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,34,Damaging,"30,67","16,17"
"low bq, low freq, many artifacts, many samples",UPN2_075,15,90631886,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn156Thr/c.467A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),13087,144,13308,"0,0108205591",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,34,Damaging,"30,81","16,99"
"low bq, low freq, many artifacts, many samples",UPN2_076,15,90631886,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn156Thr/c.467A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),8509,115,8663,"0,0132748471",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,34,Damaging,"30,05","18,23"
"low bq, low freq, many artifacts, many samples",UPN2_077,15,90631886,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn156Thr/c.467A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),8515,105,8675,"0,0121037464",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,34,Damaging,"30,19","18,58"
"low bq, low freq, many artifacts, many samples",UPN2_078,15,90631886,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn156Thr/c.467A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),10673,159,10884,"0,0146085998",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,34,Damaging,"30,01","17,8"
"low bq, low freq, many artifacts, many samples",UPN2_079,15,90631886,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn156Thr/c.467A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),6566,80,6701,"0,0119385166",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,34,Damaging,"30,38","17,3"
"low bq, low freq, many artifacts, many samples",UPN2_080,15,90631886,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn156Thr/c.467A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),12083,163,12339,"0,0132101467",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,34,Damaging,"30,24","16,9"
"low bq, low freq, many artifacts, many samples",UPN2_081,15,90631886,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn156Thr/c.467A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),14496,164,14733,"0,0111314736",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,34,Damaging,"30,47","16,88"
"low bq, low freq, many artifacts, many samples",UPN2_082,15,90631886,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn156Thr/c.467A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),8252,99,8393,"0,0117955439",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,34,Damaging,"30,49","18,34"
"low bq, low freq, many artifacts, many samples",UPN2_083,15,90631886,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn156Thr/c.467A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),12010,168,12235,"0,0137310993",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,34,Damaging,"29,93","16,73"
"low bq, low freq, many artifacts, many samples",UPN2_084,15,90631886,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn156Thr/c.467A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),12395,209,12695,"0,0164631745",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,34,Damaging,"29,73","17,17"
"low bq, low freq, many artifacts, many samples",UPN2_085,15,90631886,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn156Thr/c.467A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),6506,83,6629,"0,0125207422",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,34,Damaging,"30,21","17,08"
"low bq, low freq, many artifacts, many samples",UPN2_086,15,90631886,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn156Thr/c.467A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),4216,66,4305,"0,0153310105",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,34,Damaging,"29,98","17,88"
"low bq, low freq, many artifacts, many samples",UPN2_087,15,90631886,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn156Thr/c.467A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),11225,148,11435,"0,0129427197",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,34,Damaging,"30,3","18,92"
"low bq, low freq, many artifacts",UPN2_088,15,90631886,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn156Thr/c.467A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),8620,90,8763,"0,0102704553",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,34,Damaging,"30,84","17,2"
"low bq, low freq, many artifacts, many samples",UPN2_059,15,90631887,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn156His/c.466A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),7014,78,7113,"0,0109658372",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,0,Damaging,"30,11","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_061,15,90631887,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn156His/c.466A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),13082,166,13298,"0,0124830802",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,0,Damaging,"30,01","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_062,15,90631887,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn156His/c.466A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),14305,173,14532,"0,0119047619",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,0,Damaging,"29,77","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_063,15,90631887,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn156His/c.466A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),13544,157,13757,"0,0114123719",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,0,Damaging,"30,16","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_064,15,90631887,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn156His/c.466A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),13080,150,13287,"0,0112892301",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,0,Damaging,"30,02","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_065,15,90631887,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn156His/c.466A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),6657,71,6746,"0,0105247554",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,0,Damaging,"30,11","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_068,15,90631887,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn156His/c.466A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),8322,99,8457,"0,0117062788",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,0,Damaging,"29,76","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_069,15,90631887,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn156His/c.466A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),11245,150,11430,"0,0131233596",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,0,Damaging,30,"14,81"
"low bq, low freq, many artifacts, many samples",UPN2_070,15,90631887,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn156His/c.466A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),7369,93,7498,"0,0124033075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,0,Damaging,"29,85","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_071,15,90631887,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn156His/c.466A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),8823,114,8969,"0,0127104471",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,0,Damaging,"30,03","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_072,15,90631887,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn156His/c.466A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),12157,134,12341,"0,0108581152",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,0,Damaging,"29,93","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_073,15,90631887,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn156His/c.466A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),7768,81,7880,"0,0102791878",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,0,Damaging,"30,13","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_074,15,90631887,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn156His/c.466A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),4460,47,4525,"0,0103867403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,0,Damaging,"30,59","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_076,15,90631887,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn156His/c.466A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),8532,91,8662,"0,0105056569",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,0,Damaging,"29,75","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_077,15,90631887,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn156His/c.466A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),8530,114,8674,"0,0131427254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,0,Damaging,"30,01","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_078,15,90631887,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn156His/c.466A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),10710,123,10883,"0,0113020307",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,0,Damaging,"29,93","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_079,15,90631887,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn156His/c.466A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),6611,69,6701,"0,0102969706",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,0,Damaging,"30,22","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_080,15,90631887,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn156His/c.466A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),12156,143,12336,"0,0115920882",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,0,Damaging,"29,85","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_081,15,90631887,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn156His/c.466A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),14499,180,14733,"0,012217471",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,0,Damaging,"30,16","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_083,15,90631887,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn156His/c.466A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),12006,178,12235,"0,0145484266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,0,Damaging,"29,7","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_084,15,90631887,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn156His/c.466A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),12476,158,12693,"0,0124478059",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,0,Damaging,"29,51","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_085,15,90631887,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn156His/c.466A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),6522,77,6628,"0,0116173808",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,0,Damaging,"29,97","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_086,15,90631887,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn156His/c.466A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),4230,56,4304,"0,0130111524",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,0,Damaging,"29,58","14,23"
"low bq, low freq, many artifacts",UPN2_087,15,90631887,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn156His/c.466A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),11260,139,11435,"0,0121556624",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,0,Damaging,30,"14,71"
"low bq, low freq, many artifacts, many samples",UPN2_001,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),10995,197,11358,"0,0173446029",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"29,43","15,01"
"low bq, many samples",UPN2_014,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),12784,356,13341,"0,0266846563",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,57","14,86"
"low bq, many samples",UPN2_015,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),20012,690,20977,"0,0328931687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,36","15,22"
"low bq, many samples",UPN2_016,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),9888,292,10318,"0,0283000582",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,75","14,92"
"low bq, many samples",UPN2_017,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),6066,175,6312,"0,0277249683",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,49","14,81"
"low bq, many samples",UPN2_018,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),10662,299,11101,"0,0269345104",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,47","14,94"
"low bq, many samples",UPN2_019,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),11034,371,11558,"0,0320989791",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,38","14,74"
"low bq, many samples",UPN2_020,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),9022,224,9372,"0,0239009816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,6","15,5"
"low bq, many samples",UPN2_021,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),11229,314,11702,"0,02683302",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,54","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_002,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),13355,250,13793,"0,0181251359",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"29,09","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_003,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),2511,53,2600,"0,0203846154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"29,12","14,89"
"low bq, many samples",UPN2_022,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),14951,464,15629,"0,0296883998",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,47","15,16"
"low bq, many samples",UPN2_023,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),15543,441,16208,"0,0272087858",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,57","15,16"
"low bq, many samples",UPN2_041,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),4644,131,4869,"0,0269049086",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"29,06","14,79"
"low bq, many samples",UPN2_024,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),6688,197,6980,"0,0282234957",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,51","14,64"
"low bq, many samples",UPN2_025,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),19214,522,20019,"0,0260752285",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,73","15,06"
"low bq, many samples",UPN2_026,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),16765,550,17570,"0,031303358",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,35","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_004,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),1387,25,1428,"0,0175070028",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"29,15",15
"low bq, many samples",UPN2_027,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),18020,583,18845,"0,030936588",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,54","15,47"
"low bq, many samples",UPN2_089,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),13935,394,14416,"0,0273307436",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,95","14,7"
"low bq, many samples",UPN2_042,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),21157,617,22238,"0,0277453008",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,96","15,01"
"low bq, many samples",UPN2_028,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),13881,508,14585,"0,0348303051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,36","14,86"
"low bq, many samples",UPN2_043,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),15656,419,16337,"0,0256473037",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"29,12","15,3"
"low bq, many samples",UPN2_044,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),12491,376,13135,"0,0286258089",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,85","14,87"
"low bq, many samples",UPN2_029,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),15939,475,16628,"0,0285662738",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,65","14,83"
"low bq, many samples",UPN2_030,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),15483,463,16177,"0,0286208815",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,61","15,03"
"low bq, many samples",UPN2_031,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),10983,349,11497,"0,030355745",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,49","15,17"
"low bq, low freq, many artifacts, many samples",UPN2_005,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),4200,78,4336,"0,0179889299",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"29,28","14,99"
"low bq, many samples",UPN2_045,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),18000,534,18914,"0,0282330549",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,97","14,9"
"low bq, many samples",UPN2_032,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),5439,175,5703,"0,0306856041",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,74","15,48"
"low bq, many samples",UPN2_046,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),25289,870,26672,"0,0326184763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,9","14,94"
"low bq, many samples",UPN2_033,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),11832,318,12334,"0,0257823901",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,76","14,82"
"low bq, many samples",UPN2_034,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),4654,144,4858,"0,0296418279",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,24","14,47"
"low bq, many samples",UPN2_047,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),27849,865,29275,"0,0295473954",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"29,03","14,82"
"low bq, many samples",UPN2_048,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),10746,313,11277,"0,0277556088",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"29,01","14,98"
"low bq, many samples",UPN2_035,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),13781,402,14400,"0,0279166667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,59","15,49"
"low bq, many samples",UPN2_036,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),18179,547,18941,"0,028879151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,73","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_006,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),7188,115,7398,"0,0155447418",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"29,21","15,23"
"low bq, many samples",UPN2_049,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),21854,649,22910,"0,0283282409",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,29,"15,01"
"low bq, many samples",UPN2_050,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),18507,589,19448,"0,0302858906",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,99","15,06"
"low bq, many samples",UPN2_037,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),23711,858,25022,"0,034289825",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,37","14,95"
"low bq, many samples",UPN2_051,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),20760,565,21723,"0,0260092989",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"29,08","14,73"
"low bq, many samples",UPN2_052,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),16946,531,17784,"0,0298582996",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,97","15,01"
"low bq, many samples",UPN2_038,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),25696,803,26867,"0,0298879667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,47","15,07"
"low bq, many samples",UPN2_039,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),17169,570,17991,"0,0316825079",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,57","15,04"
"low bq, many samples",UPN2_053,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),23018,761,24262,"0,031365922",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,88","15,2"
"low bq, many samples",UPN2_054,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),14405,506,15222,"0,0332413612",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,71","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_007,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),26655,402,27429,"0,014656021",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"29,52","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_008,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),39148,738,40383,"0,0182750167",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"29,18","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_009,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),32965,590,34003,"0,0173514102",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"29,31","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_010,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),22269,420,22985,"0,0182727866",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"29,08","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_011,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),23677,400,24405,"0,016390084",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"29,32","15,27"
"low bq, many samples",UPN2_055,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),24663,722,25875,"0,0279033816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,93","15,01"
"low bq, many samples",UPN2_056,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),10946,329,11488,"0,0286385794",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,96","15,57"
"low bq, many samples",UPN2_090,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),10742,319,11167,"0,0285663115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"29,07","14,9"
"low bq, many samples",UPN2_057,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),23107,679,24283,"0,0279619487",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,29,"14,92"
"low bq, many samples",UPN2_058,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),32228,963,33895,"0,0284112701",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"29,04","14,76"
"low bq, many samples",UPN2_059,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),12828,698,13709,"0,050915457",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"27,97","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_012,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),13933,224,14372,"0,0155858614",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"29,37","14,95"
"low bq, many samples",UPN2_060,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),17632,942,18845,"0,0499867339",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,09","15,28"
"low bq, many samples",UPN2_040,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),9357,277,9776,"0,0283346972",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,61","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_013,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),7403,122,7614,"0,0160231153",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"29,33","14,89"
"low bq, many samples",UPN2_091,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),10852,308,11253,"0,027370479",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"29,04","15,11"
"low bq, many samples",UPN2_092,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),8048,233,8371,"0,0278341895",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,87","14,51"
"low bq, many samples",UPN2_093,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),11236,339,11660,"0,0290737564",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"29,02","14,96"
"low bq, many samples",UPN2_061,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),23822,1332,25502,"0,0522311976",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"27,92","15,55"
"low bq, many samples",UPN2_062,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),25930,1522,27823,"0,0547029436",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"27,74","15,52"
"low bq, many samples",UPN2_063,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),24613,1387,26406,"0,0525259411",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"27,93","15,45"
"low bq, many samples",UPN2_064,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),23895,1331,25558,"0,0520776274",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"27,95","15,43"
"low bq, many samples",UPN2_065,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),12019,631,12861,"0,0490630589",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,01","15,51"
"low bq, many samples",UPN2_066,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),10476,545,11189,"0,048708553",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,05","15,57"
"low bq, many samples",UPN2_067,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),11845,634,12667,"0,0500513144",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,18","15,14"
"low bq, many samples, no database",UPN2_068,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),15056,913,16178,"0,0564346644",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"27,73","15,53"
"low bq, many samples",UPN2_069,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),20413,1116,21904,"0,0509495982",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"27,84","15,57"
"low bq, many samples",UPN2_070,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),13381,780,14361,"0,0543137665",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"27,75","15,42"
"low bq, many samples, no database",UPN2_071,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),15943,889,17096,"0,0520004679",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,04","15,74"
"low bq, many samples",UPN2_072,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),22099,1118,23543,"0,0474875759",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"27,89","15,46"
"low bq, many samples",UPN2_073,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),14217,768,15194,"0,0505462683",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"27,94","15,58"
"low bq, many samples",UPN2_074,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),8166,406,8695,"0,046693502",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"27,94","15,48"
"low bq, many samples",UPN2_075,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),23908,1271,25583,"0,0496814291",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,11","15,48"
"low bq, many samples",UPN2_076,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),15528,804,16575,"0,0485067873",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"27,81","15,57"
"low bq, many samples",UPN2_077,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),15566,830,16640,"0,0498798077",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"27,75","15,24"
"low bq, many samples",UPN2_078,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),19478,1159,20930,"0,0553750597",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"27,8","15,44"
"low bq, many samples, no database",UPN2_079,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),12040,660,12896,"0,05117866",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"27,95","15,76"
"low bq, many samples, no database",UPN2_080,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),22071,1219,23615,"0,0516197332",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"27,88","15,6"
"low bq, many samples",UPN2_081,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),26548,1322,28320,"0,046680791",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"27,95","15,44"
"low bq, many samples",UPN2_082,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),15025,803,16064,"0,0499875498",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,28,"15,42"
"low bq, many samples",UPN2_083,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),21710,1310,23346,"0,0561123961",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"27,79","15,42"
"low bq, many samples, no database",UPN2_084,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),22606,1329,24313,"0,0546621149",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"27,76","15,43"
"low bq, many samples",UPN2_085,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),11866,638,12694,"0,0502599653",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"27,85","15,49"
"low bq, many samples",UPN2_086,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),7699,471,8282,"0,0568703212",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"27,79","15,23"
"low bq, many samples",UPN2_087,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),20533,1063,21922,"0,0484901013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"27,91","15,5"
"low bq, many samples",UPN2_088,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),15845,800,16868,"0,0474270809",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"27,97","15,13"
"low bq, many samples",UPN2_094,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),12149,367,12610,"0,0291038858",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,98","14,74"
"low bq, many samples",UPN2_095,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),13582,466,14166,"0,0328956657",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,79",15
"low bq, many samples",UPN2_096,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),11537,347,11985,"0,0289528577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,98","15,04"
"low bq, many samples",UPN2_097,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),14016,395,14506,"0,0272301117",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,9","14,81"
"low bq, many samples",UPN2_098,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),12240,370,12736,"0,0290515075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,98","15,02"
"low bq, many samples",UPN2_099,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),6150,197,6384,"0,030858396",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,97","14,73"
"low bq, many samples",UPN2_100,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),11282,269,11639,"0,0231119512",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,91","15,16"
"low bq, many samples",UPN2_101,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),12489,463,13050,"0,0354789272",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,91","15,03"
"low bq, many samples",UPN2_102,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),11222,378,11673,"0,032382421",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,96","14,87"
"low bq, many samples",UPN2_103,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),10687,362,11116,"0,0325656711",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,93","14,93"
"low bq, many samples",UPN2_104,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),13467,428,13994,"0,0305845362",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,87","14,65"
"low bq, many samples",UPN2_105,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),12328,400,12798,"0,0312548836",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,95","14,79"
"low bq, many samples",UPN2_106,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),15872,472,16465,"0,0286668691",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,29,"14,86"
"low bq, many samples",UPN2_107,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),18488,596,19266,"0,0309353265",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"29,02","14,91"
"low bq, many samples",UPN2_108,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),17677,539,18360,"0,0293572985",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,96","15,14"
"low bq, many samples",UPN2_109,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),16447,490,17057,"0,0287272088",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,87","14,72"
"low bq, many samples",UPN2_110,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),14321,449,14857,"0,0302214444",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,83","14,98"
low bq,UPN2_111,15,90631893,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys154Gly/c.460T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),14358,520,14973,"0,0347291792",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,83",Deleterious,0,Damaging,"28,94","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_059,15,90631898,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile152Ser/c.455T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),13671,174,13952,"0,0124713303",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,68",Deleterious,"0,01",Damaging,"27,81","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_060,15,90631898,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile152Ser/c.455T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),18839,257,19211,"0,0133777523",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,68",Deleterious,"0,01",Damaging,"27,84","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_061,15,90631898,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile152Ser/c.455T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),25488,390,26038,"0,0149781089",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,68",Deleterious,"0,01",Damaging,"27,64",15
"low bq, low freq, many artifacts, many samples",UPN2_062,15,90631898,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile152Ser/c.455T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),27795,410,28410,"0,0144315382",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,68",Deleterious,"0,01",Damaging,"27,4","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_063,15,90631898,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile152Ser/c.455T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),26363,370,26940,"0,0137342242",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,68",Deleterious,"0,01",Damaging,"27,79","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_064,15,90631898,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile152Ser/c.455T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),25524,354,26034,"0,0135976031",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,68",Deleterious,"0,01",Damaging,"27,62","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_065,15,90631898,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile152Ser/c.455T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),12906,194,13200,"0,0146969697",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,68",Deleterious,"0,01",Damaging,"27,72","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_066,15,90631898,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile152Ser/c.455T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),11241,144,11455,"0,0125709297",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,68",Deleterious,"0,01",Damaging,"27,83","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_067,15,90631898,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile152Ser/c.455T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),12657,162,12903,"0,0125552197",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,68",Deleterious,"0,01",Damaging,"28,11","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_068,15,90631898,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile152Ser/c.455T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),16151,269,16514,"0,0162892092",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,68",Deleterious,"0,01",Damaging,"27,42","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_069,15,90631898,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile152Ser/c.455T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),21874,344,22373,"0,015375676",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,68",Deleterious,"0,01",Damaging,"27,67","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_070,15,90631898,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile152Ser/c.455T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),14311,242,14652,"0,0165165165",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,68",Deleterious,"0,01",Damaging,"27,35","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_071,15,90631898,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile152Ser/c.455T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),17158,278,17548,"0,0158422612",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,68",Deleterious,"0,01",Damaging,"27,72","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_072,15,90631898,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile152Ser/c.455T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),23602,355,24105,"0,014727235",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,68",Deleterious,"0,01",Damaging,"27,63","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_073,15,90631898,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile152Ser/c.455T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),15176,201,15476,"0,0129878522",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,68",Deleterious,"0,01",Damaging,"27,89","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_074,15,90631898,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile152Ser/c.455T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),8712,118,8881,"0,013286792",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,68",Deleterious,"0,01",Damaging,"27,87","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_075,15,90631898,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile152Ser/c.455T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),25614,318,26091,"0,0121881108",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,68",Deleterious,"0,01",Damaging,"27,98","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_076,15,90631898,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile152Ser/c.455T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),16630,252,16984,"0,0148374941",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,68",Deleterious,"0,01",Damaging,"27,55","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_077,15,90631898,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile152Ser/c.455T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),16660,238,17006,"0,0139950606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,68",Deleterious,"0,01",Damaging,"27,53","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_078,15,90631898,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile152Ser/c.455T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),20874,322,21322,"0,0151017728",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,68",Deleterious,"0,01",Damaging,"27,42","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_079,15,90631898,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile152Ser/c.455T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),12868,194,13148,"0,0147550958",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,68",Deleterious,"0,01",Damaging,"27,82","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_080,15,90631898,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile152Ser/c.455T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),23679,361,24220,"0,0149050372",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,68",Deleterious,"0,01",Damaging,"27,7","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_081,15,90631898,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile152Ser/c.455T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),28179,428,28847,"0,0148368981",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,68",Deleterious,"0,01",Damaging,"27,82","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_082,15,90631898,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile152Ser/c.455T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),16099,217,16416,"0,0132188109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,68",Deleterious,"0,01",Damaging,"27,91","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_083,15,90631898,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile152Ser/c.455T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),23378,365,23920,"0,0152591973",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,68",Deleterious,"0,01",Damaging,"27,3","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_084,15,90631898,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile152Ser/c.455T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),24325,388,24842,"0,0156187102",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,68",Deleterious,"0,01",Damaging,"27,35","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_085,15,90631898,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile152Ser/c.455T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),12669,198,12961,"0,015276599",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,68",Deleterious,"0,01",Damaging,"27,55","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_086,15,90631898,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile152Ser/c.455T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),8189,169,8417,"0,0200784127",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,68",Deleterious,"0,01",Damaging,"27,37","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_087,15,90631898,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile152Ser/c.455T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),21900,307,22349,"0,0137366325",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,68",Deleterious,"0,01",Damaging,"27,7","14,81"
"low bq, low freq, many artifacts",UPN2_088,15,90631898,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile152Ser/c.455T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),16880,210,17181,"0,0122228043",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,68",Deleterious,"0,01",Damaging,"28,15","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_059,15,90631899,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile152Leu/c.454A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),13755,156,13973,"0,0111643885",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,1,Damaging,"28,89","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_060,15,90631899,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile152Leu/c.454A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),18953,230,19247,"0,0119499143",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,1,Damaging,"28,93","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_061,15,90631899,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile152Leu/c.454A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),25666,306,26071,"0,0117371792",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,1,Damaging,"28,76","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_062,15,90631899,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile152Leu/c.454A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),27931,374,28461,"0,0131407892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,1,Damaging,"28,52","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_063,15,90631899,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile152Leu/c.454A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),26485,368,26976,"0,0136417556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,1,Damaging,"28,9","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_064,15,90631899,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile152Leu/c.454A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),25652,326,26079,"0,0125004793",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,1,Damaging,"28,9","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_065,15,90631899,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile152Leu/c.454A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),13032,137,13226,"0,010358385",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,1,Damaging,"28,96","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_066,15,90631899,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile152Leu/c.454A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),11281,136,11476,"0,0118508191",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,1,Damaging,"29,08","14,2"
"low bq, low freq, many artifacts, many samples",UPN2_067,15,90631899,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile152Leu/c.454A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),12717,147,12923,"0,0113750677",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,1,Damaging,"29,08","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_068,15,90631899,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile152Leu/c.454A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),16246,227,16547,"0,0137184988",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,1,Damaging,"28,67","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_069,15,90631899,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile152Leu/c.454A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),22023,277,22408,"0,0123616566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,1,Damaging,"28,83","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_070,15,90631899,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile152Leu/c.454A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),14431,178,14679,"0,0121261666",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,1,Damaging,"28,55","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_071,15,90631899,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile152Leu/c.454A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),17289,212,17573,"0,0120639618",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,1,Damaging,"28,91","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_072,15,90631899,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile152Leu/c.454A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),23772,271,24152,"0,0112206028",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,1,Damaging,"28,96","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_073,15,90631899,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile152Leu/c.454A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),15230,210,15492,"0,0135553834",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,1,Damaging,"28,94","15,4"
"low bq, low freq, many artifacts, many samples",UPN2_074,15,90631899,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile152Leu/c.454A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),8771,101,8898,"0,0113508654",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,1,Damaging,"28,89","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_075,15,90631899,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile152Leu/c.454A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),25752,300,26138,"0,0114775423",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,1,Damaging,"29,13","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_076,15,90631899,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile152Leu/c.454A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),16721,211,17012,"0,0124030096",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,1,Damaging,"28,82","14,09"
"low bq, low freq, many artifacts, many samples",UPN2_077,15,90631899,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile152Leu/c.454A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),16766,186,17030,"0,0109219025",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,1,Damaging,"28,77","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_078,15,90631899,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile152Leu/c.454A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),21042,238,21359,"0,0111428438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,1,Damaging,"28,62","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_079,15,90631899,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile152Leu/c.454A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),12963,156,13168,"0,0118469016",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,1,Damaging,"28,92","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_080,15,90631899,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile152Leu/c.454A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),23869,282,24259,"0,0116245517",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,1,Damaging,"28,91","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_081,15,90631899,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile152Leu/c.454A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),28453,331,28893,"0,011456062",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,1,Damaging,"29,01","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_082,15,90631899,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile152Leu/c.454A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),16215,178,16446,"0,0108233005",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,1,Damaging,"29,06","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_083,15,90631899,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile152Leu/c.454A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),23575,314,23967,"0,0131013477",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,1,Damaging,"28,68","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_084,15,90631899,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile152Leu/c.454A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),24489,269,24873,"0,0108149399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,1,Damaging,"28,57","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_085,15,90631899,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile152Leu/c.454A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),12773,146,12981,"0,0112472075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,1,Damaging,"28,85","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_086,15,90631899,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile152Leu/c.454A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),8281,118,8434,"0,0139909889",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,1,Damaging,"28,51","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_087,15,90631899,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile152Leu/c.454A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),22042,255,22392,"0,0113879957",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,1,Damaging,"28,87","15,31"
"low bq, low freq, many artifacts",UPN2_088,15,90631899,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile152Leu/c.454A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),16934,214,17201,"0,0124411371",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,1,Damaging,"29,08","14,3"
"low bq, many samples",UPN2_059,15,90631913,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val147Gly/c.440T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),13445,486,14023,"0,0346573486",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,66",Deleterious,0,Damaging,"27,31","15,52"
"low bq, many samples",UPN2_060,15,90631913,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val147Gly/c.440T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),18549,627,19325,"0,0324450194",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,66",Deleterious,0,Damaging,"27,27","15,69"
"low bq, many samples",UPN2_061,15,90631913,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val147Gly/c.440T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),24993,993,26180,"0,0379297173",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,66",Deleterious,0,Damaging,"27,09","15,5"
"low bq, bad alignment, many samples",UPN2_062,15,90631913,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val147Gly/c.440T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),27281,1114,28589,"0,0389660359",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,66",Deleterious,0,Damaging,"26,9","15,26"
"low bq, many samples",UPN2_063,15,90631913,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val147Gly/c.440T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),25864,1031,27087,"0,0380625392",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,66",Deleterious,0,Damaging,"27,27","15,5"
"low bq, many samples",UPN2_064,15,90631913,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val147Gly/c.440T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),25013,949,26162,"0,0362739852",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,66",Deleterious,0,Damaging,"27,14","15,37"
"low bq, many samples",UPN2_065,15,90631913,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val147Gly/c.440T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),12723,437,13284,"0,0328967179",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,66",Deleterious,0,Damaging,"27,38","15,54"
"low bq, many samples",UPN2_066,15,90631913,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val147Gly/c.440T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),11050,407,11522,"0,0353237285",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,66",Deleterious,0,Damaging,"27,45","15,28"
"low bq, many samples",UPN2_067,15,90631913,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val147Gly/c.440T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),12461,417,12970,"0,032151118",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,66",Deleterious,0,Damaging,"27,75","15,28"
"low bq, bad alignment, many samples",UPN2_068,15,90631913,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val147Gly/c.440T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),15798,697,16623,"0,0419298562",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,66",Deleterious,0,Damaging,"26,84","15,55"
"low bq, many samples",UPN2_069,15,90631913,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val147Gly/c.440T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),21473,851,22510,"0,0378054198",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,66",Deleterious,0,Damaging,"27,04","15,34"
"low bq, bad alignment, many samples",UPN2_070,15,90631913,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val147Gly/c.440T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),14035,602,14747,"0,0408218621",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,66",Deleterious,0,Damaging,"26,88","15,18"
"low bq, many samples",UPN2_071,15,90631913,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val147Gly/c.440T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),16801,673,17626,"0,0381822308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,66",Deleterious,0,Damaging,"27,11","15,65"
"low bq, many samples",UPN2_072,15,90631913,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val147Gly/c.440T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),23187,880,24251,"0,0362871634",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,66",Deleterious,0,Damaging,"27,1","15,29"
"low bq, many samples",UPN2_073,15,90631913,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val147Gly/c.440T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),14892,546,15537,"0,0351419193",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,66",Deleterious,0,Damaging,"27,4","15,17"
"low bq, many samples",UPN2_074,15,90631913,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val147Gly/c.440T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),8567,294,8932,"0,0329153605",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,66",Deleterious,0,Damaging,"27,42","15,17"
"low bq, many samples",UPN2_075,15,90631913,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val147Gly/c.440T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),25131,881,26220,"0,0336003051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,66",Deleterious,0,Damaging,"27,65","15,33"
"low bq, bad alignment, many samples",UPN2_076,15,90631913,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val147Gly/c.440T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),16326,617,17052,"0,0361834389",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,66",Deleterious,0,Damaging,"26,85","15,29"
"low bq, many samples",UPN2_077,15,90631913,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val147Gly/c.440T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),16336,633,17101,"0,0370153792",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,66",Deleterious,0,Damaging,"27,1","15,27"
"low bq, bad alignment, many samples",UPN2_078,15,90631913,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val147Gly/c.440T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),20480,825,21463,"0,0384382426",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,66",Deleterious,0,Damaging,"26,88","15,45"
"low bq, many samples",UPN2_079,15,90631913,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val147Gly/c.440T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),12655,458,13211,"0,0346680796",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,66",Deleterious,0,Damaging,"27,21","15,33"
"low bq, many samples",UPN2_080,15,90631913,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val147Gly/c.440T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),23261,892,24343,"0,0366429774",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,66",Deleterious,0,Damaging,"27,07","15,41"
"low bq, many samples",UPN2_081,15,90631913,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val147Gly/c.440T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),27749,1015,28992,"0,0350096578",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,66",Deleterious,0,Damaging,"27,4","15,39"
"low bq, many samples",UPN2_082,15,90631913,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val147Gly/c.440T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),15845,530,16495,"0,0321309488",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,66",Deleterious,0,Damaging,"27,43","15,32"
"low bq, bad alignment, many samples",UPN2_083,15,90631913,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val147Gly/c.440T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),22954,949,24071,"0,0394250343",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,66",Deleterious,0,Damaging,"26,75","15,32"
"low bq, bad alignment, many samples",UPN2_084,15,90631913,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val147Gly/c.440T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),23817,993,24986,"0,0397422557",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,66",Deleterious,0,Damaging,"26,86","15,44"
"low bq, many samples",UPN2_085,15,90631913,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val147Gly/c.440T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),12441,502,13034,"0,038514654",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,66",Deleterious,0,Damaging,"27,18","15,3"
"low bq, many samples",UPN2_086,15,90631913,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val147Gly/c.440T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),8060,331,8454,"0,0391530636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,66",Deleterious,0,Damaging,"27,03","15,27"
"low bq, many samples",UPN2_087,15,90631913,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val147Gly/c.440T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),21487,835,22480,"0,0371441281",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,66",Deleterious,0,Damaging,"27,12","15,36"
low bq,UPN2_088,15,90631913,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val147Gly/c.440T>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),16581,570,17246,"0,0330511423",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,66",Deleterious,0,Damaging,"27,62","15,46"
"low freq, many artifacts",UPN2_013,15,90631917,T,C,missense_variant(MODERATE|MISSENSE|Act/Gct|p.Thr146Ala/c.436A>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),7629,78,7757,"0,0100554338",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,68",Deleterious,2,Damaging,"31,04","32,81"
"many samples, homopolymer 7C, low freq",UPN2_001,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),11406,155,11568,"0,0133990318",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,12",NA
"many samples, homopolymer 7C, low freq",UPN2_014,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),13385,164,13563,"0,0120917201",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,78",NA
"many samples, homopolymer 7C, low freq",UPN2_015,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),21083,321,21365,"0,0150245729",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,26",NA
"many samples, homopolymer 7C, low freq",UPN2_016,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),10371,147,10494,"0,0140080046",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,86",NA
"many samples, homopolymer 7C, low freq",UPN2_017,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),6348,83,6429,"0,0129102504",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,56",NA
"many samples, homopolymer 7C, low freq",UPN2_018,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),11216,169,11326,"0,0149214197",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,46",NA
"many samples, homopolymer 7C, low freq",UPN2_019,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),11588,139,11746,"0,0118338158",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,45",NA
"many samples, homopolymer 7C, low freq",UPN2_020,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),9436,142,9549,"0,0148706671",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,77",NA
"many samples, homopolymer 7C, low freq",UPN2_021,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),11753,152,11900,"0,0127731092",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,81",NA
"many samples, homopolymer 7C, low freq",UPN2_002,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),13920,198,14083,"0,0140595044",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,78",NA
"many samples, homopolymer 7C, low freq",UPN2_003,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),2616,45,2655,"0,0169491525",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,93",NA
"many samples, homopolymer 7C, low freq",UPN2_022,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),15761,217,15956,"0,0135998997",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,78",NA
"many samples, homopolymer 7C, low freq",UPN2_023,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),16311,218,16525,"0,0131921331",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,61",NA
"many samples, homopolymer 7C, low freq",UPN2_024,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),6992,82,7090,"0,0115655853",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,55",NA
"many samples, homopolymer 7C, low freq",UPN2_025,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),20168,315,20405,"0,0154373928",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,79",NA
"many samples, homopolymer 7C, low freq",UPN2_026,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),17714,242,17901,"0,0135187978",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,25",NA
"many samples, homopolymer 7C, low freq",UPN2_027,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),18965,254,19179,"0,0132436519",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,52",NA
"many samples, homopolymer 7C, low freq",UPN2_089,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),14521,182,14681,"0,0123969757",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,59",NA
"many samples, homopolymer 7C, low freq",UPN2_042,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),22285,247,22694,"0,0108839341",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,68",NA
"many samples, homopolymer 7C, low freq",UPN2_028,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),14630,200,14856,"0,013462574",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,21",NA
"many samples, homopolymer 7C, low freq",UPN2_043,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),16413,248,16734,"0,0148201267",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,76",NA
"many samples, homopolymer 7C, low freq",UPN2_044,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),13111,134,13350,"0,0100374532",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,7",NA
"many samples, homopolymer 7C, low freq",UPN2_029,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),16793,227,16979,"0,0133694564",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,71",NA
"many samples, homopolymer 7C, low freq",UPN2_030,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),16235,239,16465,"0,0145156392",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,62",NA
"many samples, homopolymer 7C, low freq",UPN2_031,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),11520,141,11683,"0,0120688179",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,6",NA
"many samples, homopolymer 7C, low freq",UPN2_005,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),4366,76,4419,"0,0171984612",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,05",NA
"many samples, homopolymer 7C, low freq",UPN2_045,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),18991,227,19356,"0,0117276297",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,73",NA
"many samples, homopolymer 7C, low freq",UPN2_032,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),5722,61,5799,"0,010519055",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,67",NA
"many samples, homopolymer 7C, low freq",UPN2_046,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),26837,297,27315,"0,0108731466",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,52",NA
"many samples, homopolymer 7C, low freq",UPN2_033,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),12404,172,12546,"0,0137095489",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,92",NA
"many samples, homopolymer 7C, low freq",UPN2_047,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),29307,428,29900,"0,0143143813",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,86",NA
"many samples, homopolymer 7C, low freq",UPN2_048,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),11286,167,11530,"0,0144839549",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,79",NA
"many samples, homopolymer 7C, low freq",UPN2_035,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),14574,369,14751,"0,0250152532",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,54",NA
"many samples, homopolymer 7C, low freq",UPN2_036,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),19409,1049,19659,"0,0533597843",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,59",NA
"many samples, homopolymer 7C, low freq",UPN2_006,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),7443,135,7544,"0,0178950159",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,86",NA
"many samples, homopolymer 7C, low freq",UPN2_049,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),22928,297,23360,"0,0127140411",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,68",NA
"many samples, homopolymer 7C, low freq",UPN2_050,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),19495,210,19853,"0,0105777464",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,56",NA
"many samples, homopolymer 7C, low freq",UPN2_037,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),25176,363,25469,"0,0142526208",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,28",NA
"many samples, homopolymer 7C, low freq",UPN2_051,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),21761,253,22163,"0,0114154221",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,9",NA
"inspected, many samples, homopolymer 7C, low freq",UPN2_052,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),17866,253,18175,"0,0139202201",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,44",NA
"many samples, homopolymer 7C, low freq",UPN2_038,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),27090,388,27421,"0,0141497393",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,5",NA
"many samples, homopolymer 7C, low freq",UPN2_039,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),18554,895,18750,"0,0477333333",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,24",NA
"many samples, homopolymer 7C, low freq",UPN2_053,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),24355,308,24814,"0,0124123479",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,51",NA
"many samples, homopolymer 7C, low freq",UPN2_054,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),15297,199,15615,"0,0127441563",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,45",NA
"many samples, homopolymer 7C, low freq",UPN2_007,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),27647,400,28006,"0,0142826537",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,17",NA
"many samples, homopolymer 7C, low freq",UPN2_008,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),40739,680,41231,"0,016492445",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,77",NA
"many samples, homopolymer 7C, low freq",UPN2_009,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),34213,490,34646,"0,0141430468",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,95",NA
"many samples, homopolymer 7C, low freq",UPN2_010,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),23063,376,23417,"0,0160567109",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,82",NA
"many samples, homopolymer 7C, low freq",UPN2_011,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),24508,384,24861,"0,0154458791",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,1",NA
"many samples, homopolymer 7C, low freq",UPN2_055,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),26032,285,26460,"0,0107709751",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,58",NA
"inspected, many samples, homopolymer 7C, low freq",UPN2_056,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),11716,166,11926,"0,0139191682",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,58",NA
"many samples, homopolymer 7C, low freq",UPN2_090,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),11197,116,11354,"0,0102166637",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,75",NA
"many samples, homopolymer 7C, low freq",UPN2_057,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),24355,281,24782,"0,011338875",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,73",NA
"many samples, homopolymer 7C, low freq",UPN2_058,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),34045,413,34659,"0,0119160968",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,74",NA
"many samples, homopolymer 7C, low freq",UPN2_059,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),13658,191,14027,"0,0136165966",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,89",NA
"many samples, homopolymer 7C, low freq",UPN2_012,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),14445,217,14607,"0,014855891",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,11",NA
"many samples, homopolymer 7C, low freq",UPN2_060,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),18817,231,19340,"0,0119441572",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,78",NA
"many samples, homopolymer 7C, low freq",UPN2_040,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),10058,579,10203,"0,0567480153",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,47",NA
"many samples, homopolymer 7C, low freq",UPN2_013,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),7629,120,7757,"0,0154698982",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,04",NA
"many samples, homopolymer 7C, low freq",UPN2_091,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),11315,149,11478,"0,0129813556",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,81",NA
"many samples, homopolymer 7C, low freq",UPN2_092,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),8414,104,8538,"0,0121808386",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,7",NA
"many samples, homopolymer 7C, low freq",UPN2_093,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),11687,146,11869,"0,0123009521",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,77",NA
"many samples, homopolymer 7C, low freq",UPN2_061,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),25435,407,26190,"0,0155402826",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,57",NA
"many samples, homopolymer 7C, low freq",UPN2_062,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),27823,399,28617,"0,0139427613",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,49",NA
"many samples, homopolymer 7C, low freq",UPN2_063,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),26442,381,27108,"0,0140548915",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,74",NA
"many samples, homopolymer 7C, low freq",UPN2_064,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),25406,358,26174,"0,0136776954",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,76",NA
"many samples, homopolymer 7C, low freq",UPN2_065,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),12911,187,13290,"0,0140707299",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,88",NA
"many samples, homopolymer 7C, low freq",UPN2_066,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),11214,159,11530,"0,0137901127",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,01",NA
"many samples, homopolymer 7C, low freq",UPN2_067,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),12638,185,12975,"0,0142581888",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,97",NA
"many samples, homopolymer 7C, low freq",UPN2_068,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),16106,237,16631,"0,0142504961",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,49",NA
"many samples, homopolymer 7C, low freq",UPN2_069,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),21879,321,22523,"0,0142520979",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,73",NA
"many samples, homopolymer 7C, low freq",UPN2_070,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),14367,194,14756,"0,0131471944",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,35",NA
"many samples, homopolymer 7C, low freq",UPN2_071,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),17162,250,17635,"0,0141763538",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,72",NA
"many samples, homopolymer 7C, low freq",UPN2_072,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),23587,346,24269,"0,0142568709",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,76",NA
"many samples, homopolymer 7C, low freq",UPN2_073,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),15108,194,15543,"0,0124815029",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,93",NA
"many samples, homopolymer 7C, low freq",UPN2_074,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),8729,120,8939,"0,0134243204",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,88",NA
"many samples, homopolymer 7C, low freq",UPN2_075,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),25570,363,26236,"0,0138359506",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,92",NA
"many samples, homopolymer 7C, low freq",UPN2_076,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),16619,218,17062,"0,0127769312",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,47",NA
"many samples, homopolymer 7C, low freq",UPN2_077,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),16659,210,17115,"0,0122699387",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,62",NA
"many samples, homopolymer 7C, low freq",UPN2_078,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),20889,325,21482,"0,0151289452",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,5",NA
"many samples, homopolymer 7C, low freq",UPN2_079,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),12859,163,13218,"0,0123316689",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,82",NA
"many samples, homopolymer 7C, low freq",UPN2_080,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),23708,410,24353,"0,0168357081",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,8",NA
"many samples, homopolymer 7C, low freq",UPN2_081,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),28276,357,29018,"0,0123027087",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,84",NA
"many samples, homopolymer 7C, low freq",UPN2_082,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),16074,227,16504,"0,0137542414",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,87",NA
"many samples, homopolymer 7C, low freq",UPN2_083,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),23378,321,24092,"0,013323925",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,46",NA
"many samples, homopolymer 7C, low freq",UPN2_084,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),24321,351,24998,"0,0140411233",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,57",NA
"many samples, homopolymer 7C, low freq",UPN2_085,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),12689,202,13041,"0,0154896097",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,64",NA
"many samples, homopolymer 7C, low freq",UPN2_086,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),8224,99,8459,"0,0117035111",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,56",NA
"many samples, homopolymer 7C, low freq",UPN2_087,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),21852,268,22504,"0,011908994",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,77",NA
"many samples, homopolymer 7C, low freq",UPN2_088,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),16829,180,17258,"0,0104299455",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,09",NA
"many samples, homopolymer 7C, low freq",UPN2_094,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),12602,167,12813,"0,0130336377",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,64",NA
"many samples, homopolymer 7C, low freq",UPN2_095,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),14209,178,14410,"0,012352533",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,43",NA
"many samples, homopolymer 7C, low freq",UPN2_096,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),12056,147,12218,"0,012031429",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,65",NA
"many samples, homopolymer 7C, low freq",UPN2_097,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),14582,231,14785,"0,0156239432",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,73",NA
"many samples, homopolymer 7C, low freq",UPN2_098,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),12815,191,13011,"0,0146798863",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,69",NA
"many samples, homopolymer 7C, low freq",UPN2_099,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),6407,83,6502,"0,012765303",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,57",NA
"many samples, homopolymer 7C, low freq",UPN2_100,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),11694,136,11850,"0,0114767932",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,88",NA
"many samples, homopolymer 7C, low freq",UPN2_101,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),13070,136,13293,"0,0102309486",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,34",NA
"many samples, homopolymer 7C, low freq",UPN2_102,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),11742,170,11904,"0,014280914",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,49",NA
"many samples, homopolymer 7C, low freq",UPN2_103,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),11188,152,11346,"0,0133967918",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,4",NA
"many samples, homopolymer 7C, low freq",UPN2_104,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),14084,214,14287,"0,0149786519",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,57",NA
"many samples, homopolymer 7C, low freq",UPN2_105,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),12846,150,13029,"0,0115127792",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,57",NA
"many samples, homopolymer 7C, low freq",UPN2_106,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),16525,234,16778,"0,0139468351",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,68",NA
"many samples, homopolymer 7C, low freq",UPN2_107,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),19307,237,19577,"0,0121060428",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,59",NA
"many samples, homopolymer 7C, low freq",UPN2_108,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),18444,246,18715,"0,0131445365",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,65",NA
"many samples, homopolymer 7C, low freq",UPN2_109,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),17121,196,17391,"0,0112701972",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,58",NA
"inspected, many samples, homopolymer 7C, low freq",UPN2_110,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),14891,185,15115,"0,0122394972",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,6",NA
"many samples, homopolymer 7C, low freq",UPN2_111,15,90631917,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Thr146fs/c.435dupG|452|IDH2|protein_coding|CODING|ENST00000330062|4|TC),14997,187,15250,"0,0122622951",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,32",NA
"many samples, homopolymer 7C, low freq",UPN2_001,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),11314,199,11578,"0,0171877699",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"34,2",NA
"many samples, homopolymer 7C, low freq",UPN2_014,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),13321,211,13569,"0,0155501511",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,44",NA
"many samples, homopolymer 7C, low freq",UPN2_015,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),20891,399,21383,"0,0186596829",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,45",NA
"many samples, homopolymer 7C, low freq",UPN2_016,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),10278,182,10499,"0,0173349843",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,41",NA
"many samples, homopolymer 7C, low freq",UPN2_017,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),6301,107,6436,"0,0166252331",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,37",NA
"many samples, homopolymer 7C, low freq",UPN2_018,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),11109,176,11332,"0,015531239",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,37",NA
"many samples, homopolymer 7C, low freq",UPN2_019,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),11519,177,11758,"0,0150535805",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,51",NA
"many samples, homopolymer 7C, low freq",UPN2_020,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),9369,137,9559,"0,0143320431",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,38",NA
"many samples, homopolymer 7C, low freq",UPN2_021,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),11661,186,11908,"0,0156197514",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,43",NA
"many samples, homopolymer 7C, low freq",UPN2_002,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),13829,211,14098,"0,0149666619",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"34,18",NA
"many samples, homopolymer 7C, low freq",UPN2_003,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),2606,36,2656,"0,0135542169",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"34,19",NA
"many samples, homopolymer 7C, low freq",UPN2_022,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),15632,278,15962,"0,0174163639",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,45",NA
"many samples, homopolymer 7C, low freq",UPN2_023,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),16162,311,16547,"0,0187949477",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,43",NA
"many samples, homopolymer 7C, low freq",UPN2_041,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),5009,77,5109,"0,0150714426",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,96",NA
"many samples, homopolymer 7C, low freq",UPN2_024,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),6937,114,7090,"0,0160789845",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,43",NA
"many samples, homopolymer 7C, low freq",UPN2_025,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),19985,356,20421,"0,0174330346",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,47",NA
"many samples, homopolymer 7C, low freq",UPN2_026,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),17579,291,17925,"0,0162343096",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,39",NA
"many samples, homopolymer 7C, low freq",UPN2_004,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),1424,35,1468,"0,0238419619",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"34,01",NA
"many samples, homopolymer 7C, low freq",UPN2_027,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),18801,333,19195,"0,0173482678",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,47",NA
"many samples, homopolymer 7C, low freq",UPN2_089,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),14389,250,14702,"0,0170044892",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,61",NA
"many samples, homopolymer 7C, low freq",UPN2_042,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),22143,423,22710,"0,0186261559",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,99",NA
"many samples, homopolymer 7C, low freq",UPN2_028,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),14532,270,14861,"0,0181683601",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,46",NA
"many samples, homopolymer 7C, low freq",UPN2_043,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),16315,336,16762,"0,0200453407",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,07",NA
"many samples, homopolymer 7C, low freq",UPN2_044,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),13040,256,13362,"0,0191588086",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,02",NA
"many samples, homopolymer 7C, low freq",UPN2_029,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),16572,338,16993,"0,0198905432",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,4",NA
"many samples, homopolymer 7C, low freq",UPN2_030,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),16126,298,16481,"0,0180814271",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,48",NA
"many samples, homopolymer 7C, low freq",UPN2_031,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),11430,212,11689,"0,0181367097",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,38",NA
"many samples, homopolymer 7C, low freq",UPN2_005,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),4333,70,4422,"0,0158299412",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"34,07",NA
"many samples, homopolymer 7C, low freq",UPN2_045,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),18952,311,19370,"0,0160557563",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,04",NA
"many samples, homopolymer 7C, low freq",UPN2_032,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),5698,85,5802,"0,0146501206",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,5",NA
"many samples, homopolymer 7C, low freq",UPN2_046,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),26757,450,27361,"0,0164467673",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,04",NA
"many samples, homopolymer 7C, low freq",UPN2_033,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),12303,202,12552,"0,0160930529",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,31",NA
"many samples, homopolymer 7C, low freq",UPN2_034,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),4827,89,4927,"0,0180637305",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,46",NA
"many samples, homopolymer 7C, low freq",UPN2_047,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),29180,537,29933,"0,0179400661",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,05",NA
"many samples, homopolymer 7C, low freq",UPN2_048,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),11294,177,11536,"0,0153432732",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,03",NA
"many samples, homopolymer 7C, low freq",UPN2_035,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),14467,222,14763,"0,015037594",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,35",NA
"many samples, homopolymer 7C, low freq",UPN2_036,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),19351,277,19687,"0,0140701986",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,26",NA
"many samples, homopolymer 7C, low freq",UPN2_006,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),7368,144,7547,"0,0190804293",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"34,04",NA
"many samples, homopolymer 7C, low freq",UPN2_049,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),22828,392,23387,"0,0167614487",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,01",NA
"many samples, homopolymer 7C, low freq",UPN2_050,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),19413,342,19877,"0,0172058158",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,04",NA
"many samples, homopolymer 7C, low freq",UPN2_037,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),24975,426,25485,"0,0167157151",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,48",NA
"many samples, homopolymer 7C, low freq",UPN2_051,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),21658,373,22190,"0,0168093736",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,02",NA
"inspected, many samples, homopolymer 7C, low freq",UPN2_052,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),17779,301,18193,"0,0165448249",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,08",NA
"many samples, homopolymer 7C, low freq",UPN2_038,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),26936,399,27448,"0,0145365783",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,46",NA
"many samples, homopolymer 7C, low freq",UPN2_039,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),18372,334,18772,"0,0177924569",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,35",NA
"many samples, homopolymer 7C, low freq",UPN2_053,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),24194,494,24842,"0,0198856775",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,12",NA
"many samples, homopolymer 7C, low freq",UPN2_054,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),15256,284,15630,"0,0181701855",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,09",NA
"many samples, homopolymer 7C, low freq",UPN2_007,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),27454,442,28042,"0,0157620712",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"34,06",NA
"many samples, homopolymer 7C, low freq",UPN2_008,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),40409,666,41271,"0,0161372392",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"34,05",NA
"many samples, homopolymer 7C, low freq",UPN2_009,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),33975,534,34681,"0,0153974799",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"34,06",NA
"many samples, homopolymer 7C, low freq",UPN2_010,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),22906,403,23436,"0,0171957672",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"34,09",NA
"many samples, homopolymer 7C, low freq",UPN2_011,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),24400,387,24880,"0,0155546624",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"34,1",NA
"many samples, homopolymer 7C, low freq",UPN2_055,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),25846,476,26488,"0,0179704017",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,15",NA
"inspected, many samples, homopolymer 7C, low freq",UPN2_056,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),11717,150,11939,"0,0125638663",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,05",NA
"many samples, homopolymer 7C, low freq",UPN2_090,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),11131,192,11374,"0,0168806049",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,59",NA
"many samples, homopolymer 7C, low freq",UPN2_057,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),24206,480,24810,"0,0193470375",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,01",NA
"many samples, homopolymer 7C, low freq",UPN2_058,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),33905,600,34702,"0,0172900697",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,07",NA
"many samples, homopolymer 7C, low freq",UPN2_059,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),13779,189,14042,"0,0134596211",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,73",NA
"many samples, homopolymer 7C, low freq",UPN2_012,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),14321,263,14622,"0,0179865955",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"34,19",NA
"many samples, homopolymer 7C, low freq",UPN2_060,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),18927,302,19360,"0,0155991736",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,74",NA
"many samples, homopolymer 7C, low freq",UPN2_040,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),10005,178,10215,"0,0174253549",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,25",NA
"many samples, homopolymer 7C, low freq",UPN2_013,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),7596,113,7762,"0,0145581036",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"34,1",NA
"many samples, homopolymer 7C, low freq",UPN2_091,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),11226,227,11491,"0,0197545905",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,62",NA
"many samples, homopolymer 7C, low freq",UPN2_092,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),8353,166,8550,"0,0194152047",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,58",NA
"many samples, homopolymer 7C, low freq",UPN2_093,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),11654,189,11880,"0,0159090909",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,63",NA
"many samples, homopolymer 7C, low freq",UPN2_061,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),25624,438,26224,"0,0167022575",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,71",NA
"many samples, homopolymer 7C, low freq",UPN2_062,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),28032,463,28658,"0,0161560472",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,63",NA
"many samples, homopolymer 7C, low freq",UPN2_063,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),26539,465,27163,"0,0171188749",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,69",NA
"many samples, homopolymer 7C, low freq",UPN2_064,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),25656,414,26209,"0,0157961006",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,71",NA
"many samples, homopolymer 7C, low freq",UPN2_065,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),13004,234,13314,"0,0175754845",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,59",NA
"many samples, homopolymer 7C, low freq",UPN2_066,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),11317,147,11546,"0,012731682",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,7",NA
"many samples, homopolymer 7C, low freq",UPN2_067,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),12727,209,13012,"0,0160620965",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,6",NA
"many samples, homopolymer 7C, low freq",UPN2_068,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),16278,295,16654,"0,0177134622",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,66",NA
"many samples, homopolymer 7C, low freq",UPN2_069,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),22074,349,22544,"0,0154808375",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,73",NA
"many samples, homopolymer 7C, low freq",UPN2_070,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),14473,211,14771,"0,0142847471",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,63",NA
"many samples, homopolymer 7C, low freq",UPN2_071,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),17287,248,17657,"0,0140454211",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,51",NA
"many samples, homopolymer 7C, low freq",UPN2_072,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),23750,422,24312,"0,0173576834",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,58",NA
"many samples, homopolymer 7C, low freq",UPN2_073,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),15188,263,15568,"0,016893628",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,83",NA
"many samples, homopolymer 7C, low freq",UPN2_074,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),8769,140,8956,"0,0156319786",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,83",NA
"many samples, homopolymer 7C, low freq",UPN2_075,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),25632,473,26269,"0,0180060147",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,77",NA
"many samples, homopolymer 7C, low freq",UPN2_076,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),16704,296,17095,"0,0173150044",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,71",NA
"many samples, homopolymer 7C, low freq",UPN2_077,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),16811,228,17138,"0,0133037694",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,71",NA
"many samples, homopolymer 7C, low freq",UPN2_078,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),21061,338,21511,"0,0157128911",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,75",NA
"many samples, homopolymer 7C, low freq",UPN2_079,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),12951,187,13237,"0,0141270681",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,69",NA
"many samples, homopolymer 7C, low freq",UPN2_080,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),23915,338,24381,"0,0138632542",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,62",NA
"many samples, homopolymer 7C, low freq",UPN2_081,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),28415,465,29067,"0,015997523",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,71",NA
"many samples, homopolymer 7C, low freq",UPN2_082,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),16156,260,16523,"0,0157356412",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,75",NA
"many samples, homopolymer 7C, low freq",UPN2_083,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),23555,418,24126,"0,0173257067",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,66",NA
"many samples, homopolymer 7C, low freq",UPN2_084,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),24515,338,25031,"0,013503256",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,61",NA
"many samples, homopolymer 7C, low freq",UPN2_085,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),12828,153,13056,"0,01171875",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,55",NA
"many samples, homopolymer 7C, low freq",UPN2_086,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),8285,133,8473,"0,0156969196",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,63",NA
"many samples, homopolymer 7C, low freq",UPN2_087,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),22034,371,22540,"0,0164596273",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,66",NA
"many samples, homopolymer 7C, low freq",UPN2_088,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),16923,264,17281,"0,0152768937",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"32,79",NA
"many samples, homopolymer 7C, low freq",UPN2_094,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),12564,218,12825,"0,0169980507",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,64",NA
"many samples, homopolymer 7C, low freq",UPN2_095,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),14178,194,14425,"0,0134488735",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,67",NA
"many samples, homopolymer 7C, low freq",UPN2_096,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),12011,184,12229,"0,0150462017",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,62",NA
"many samples, homopolymer 7C, low freq",UPN2_097,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),14530,211,14805,"0,0142519419",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,59",NA
"many samples, homopolymer 7C, low freq",UPN2_098,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),12728,219,13017,"0,016824153",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,67",NA
"many samples, homopolymer 7C, low freq",UPN2_099,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),6374,116,6510,"0,0178187404",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,75",NA
"many samples, homopolymer 7C, low freq",UPN2_100,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),11649,173,11861,"0,0145856167",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,59",NA
"many samples, homopolymer 7C, low freq",UPN2_101,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),13062,187,13304,"0,014055923",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,71",NA
"many samples, homopolymer 7C, low freq",UPN2_102,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),11629,234,11916,"0,0196374622",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,6",NA
"many samples, homopolymer 7C, low freq",UPN2_103,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),11133,200,11364,"0,0175994368",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,79",NA
"many samples, homopolymer 7C, low freq",UPN2_104,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),14029,217,14305,"0,0151695211",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,6",NA
"many samples, homopolymer 7C, low freq",UPN2_105,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),12806,183,13040,"0,0140337423",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,67",NA
"many samples, homopolymer 7C, low freq",UPN2_106,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),16473,263,16795,"0,0156594224",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,57",NA
"many samples, homopolymer 7C, low freq",UPN2_107,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),19164,356,19598,"0,0181651189",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,59",NA
"many samples, homopolymer 7C, low freq",UPN2_108,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),18391,301,18738,"0,016063614",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,62",NA
"many samples, homopolymer 7C, low freq",UPN2_109,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),17053,311,17417,"0,0178561176",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,7",NA
"inspected, many samples, homopolymer 7C, low freq",UPN2_110,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),14804,271,15133,"0,0179078834",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,67",NA
"many samples, homopolymer 7C, low freq",UPN2_111,15,90631917,TC,T,frameshift_variant(HIGH||ggg/|p.Thr146fs/c.435delG|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),14928,264,15263,"0,0172967307",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,63",NA
"low bq, low freq, many artifacts, many samples",UPN2_059,15,90631929,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile142Leu/c.424A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),13780,200,14036,"0,0142490738",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,86",Neutral,1,Damaging,"28,31","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_060,15,90631929,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile142Leu/c.424A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),19051,253,19370,"0,0130614352",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,86",Neutral,1,Damaging,"28,21","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_061,15,90631929,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile142Leu/c.424A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),25775,347,26204,"0,0132422531",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,86",Neutral,1,Damaging,"28,07","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_062,15,90631929,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile142Leu/c.424A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),28098,453,28649,"0,0158120702",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,86",Neutral,1,Damaging,"27,72","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_063,15,90631929,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile142Leu/c.424A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),26644,395,27150,"0,0145488029",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,86",Neutral,1,Damaging,"28,08","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_064,15,90631929,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile142Leu/c.424A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),25755,362,26211,"0,0138109954",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,86",Neutral,1,Damaging,"27,98","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_065,15,90631929,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile142Leu/c.424A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),13059,175,13298,"0,0131598737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,86",Neutral,1,Damaging,"28,02","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_066,15,90631929,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile142Leu/c.424A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),11341,152,11540,"0,0131715771",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,86",Neutral,1,Damaging,"28,28","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_067,15,90631929,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile142Leu/c.424A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),12774,175,13008,"0,0134532595",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,86",Neutral,1,Damaging,"28,41","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_068,15,90631929,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile142Leu/c.424A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),16360,224,16641,"0,0134607295",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,86",Neutral,1,Damaging,"27,68","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_069,15,90631929,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile142Leu/c.424A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),22129,331,22536,"0,0146876109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,86",Neutral,1,Damaging,"27,98","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_070,15,90631929,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile142Leu/c.424A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),14471,228,14761,"0,015446108",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,86",Neutral,1,Damaging,"27,72","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_071,15,90631929,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile142Leu/c.424A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),17334,247,17667,"0,0139808683",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,86",Neutral,1,Damaging,"28,08","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_072,15,90631929,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile142Leu/c.424A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),23838,365,24300,"0,0150205761",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,86",Neutral,1,Damaging,"28,01","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_073,15,90631929,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile142Leu/c.424A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),15302,218,15579,"0,013993196",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,86",Neutral,1,Damaging,"28,24","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_074,15,90631929,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile142Leu/c.424A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),8814,107,8955,"0,011948632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,86",Neutral,1,Damaging,"28,23","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_075,15,90631929,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile142Leu/c.424A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),25854,301,26269,"0,011458373",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,86",Neutral,1,Damaging,"28,38","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_076,15,90631929,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile142Leu/c.424A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),16782,247,17094,"0,0144495144",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,86",Neutral,1,Damaging,"27,85","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_077,15,90631929,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile142Leu/c.424A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),16807,252,17139,"0,0147033082",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,86",Neutral,1,Damaging,"27,85","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_078,15,90631929,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile142Leu/c.424A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),21120,311,21509,"0,0144590636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,86",Neutral,1,Damaging,"27,75","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_079,15,90631929,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile142Leu/c.424A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),13031,168,13228,"0,0127003326",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,86",Neutral,1,Damaging,"27,96","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_080,15,90631929,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile142Leu/c.424A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),23934,343,24367,"0,0140764148",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,86",Neutral,1,Damaging,"28,11","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_081,15,90631929,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile142Leu/c.424A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),28535,398,29066,"0,0136929746",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,86",Neutral,1,Damaging,"28,3","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_082,15,90631929,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile142Leu/c.424A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),16221,218,16520,"0,0131961259",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,86",Neutral,1,Damaging,"28,25","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_083,15,90631929,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile142Leu/c.424A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),23594,394,24116,"0,0163377011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,86",Neutral,1,Damaging,"27,81","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_084,15,90631929,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile142Leu/c.424A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),24536,379,25018,"0,0151490927",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,86",Neutral,1,Damaging,"27,76","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_085,15,90631929,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile142Leu/c.424A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),12826,179,13056,"0,0137101716",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,86",Neutral,1,Damaging,"27,95","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_086,15,90631929,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile142Leu/c.424A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),8293,130,8475,"0,015339233",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,86",Neutral,1,Damaging,"27,79","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_087,15,90631929,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile142Leu/c.424A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),22116,306,22523,"0,013586112",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,86",Neutral,1,Damaging,"28,14","14,55"
"low bq, low freq, many artifacts",UPN2_088,15,90631929,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile142Leu/c.424A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),16973,245,17277,"0,0141807027",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,86",Neutral,1,Damaging,"28,55","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_059,15,90631931,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn141Thr/c.422A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),13785,169,14037,"0,0120396096",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"27,85",15
"low bq, low freq, many artifacts, many samples",UPN2_060,15,90631931,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn141Thr/c.422A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),19079,198,19370,"0,0102219928",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"27,85","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_061,15,90631931,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn141Thr/c.422A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),25762,270,26204,"0,0103037704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"27,49","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_062,15,90631931,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn141Thr/c.422A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),28098,355,28647,"0,0123922226",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"27,1","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_063,15,90631931,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn141Thr/c.422A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),26673,322,27147,"0,0118613475",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"27,6","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_064,15,90631931,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn141Thr/c.422A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),25770,278,26214,"0,0106050202",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"27,58","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_066,15,90631931,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn141Thr/c.422A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),11354,125,11541,"0,0108309505",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"27,7","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_067,15,90631931,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn141Thr/c.422A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),12803,139,13010,"0,0106840892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"27,94","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_068,15,90631931,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn141Thr/c.422A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),16335,203,16641,"0,0121987861",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"27,17","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_069,15,90631931,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn141Thr/c.422A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),22093,261,22536,"0,0115814696",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"27,53","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_070,15,90631931,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn141Thr/c.422A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),14491,171,14760,"0,0115853659",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"27,19","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_071,15,90631931,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn141Thr/c.422A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),17339,213,17666,"0,0120570588",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"27,65","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_072,15,90631931,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn141Thr/c.422A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),23857,257,24298,"0,0105770022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"27,62","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_074,15,90631931,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn141Thr/c.422A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),8804,99,8956,"0,011054042",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"27,85","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_076,15,90631931,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn141Thr/c.422A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),16793,201,17096,"0,0117571362",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"27,29","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_077,15,90631931,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn141Thr/c.422A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),16831,191,17141,"0,0111428738",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"27,57","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_078,15,90631931,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn141Thr/c.422A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),21135,250,21504,"0,011625744",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"27,15","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_080,15,90631931,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn141Thr/c.422A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),23978,249,24369,"0,0102178998",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"27,64","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_081,15,90631931,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn141Thr/c.422A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),28543,304,29064,"0,0104596752",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"27,79","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_082,15,90631931,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn141Thr/c.422A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),16253,168,16517,"0,0101713386",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"27,86","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_083,15,90631931,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn141Thr/c.422A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),23679,294,24117,"0,012190571",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"27,19","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_084,15,90631931,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn141Thr/c.422A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),24500,336,25018,"0,0134303302",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"27,3","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_085,15,90631931,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn141Thr/c.422A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),12823,147,13057,"0,0112583289",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"27,48","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_086,15,90631931,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn141Thr/c.422A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),8331,101,8475,"0,0119174041",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"27,2","14,39"
"low bq, low freq, many artifacts",UPN2_087,15,90631931,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn141Thr/c.422A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),22106,271,22523,"0,0120321449",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"27,59","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_070,15,90631932,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn141His/c.421A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),14521,151,14759,"0,0102310455",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,0,Damaging,"29,12","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_086,15,90631932,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn141His/c.421A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),8347,89,8477,"0,0104989973",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,0,Damaging,"29,2","14,3"
"Hotspot, inspected, low freq, many artifacts",UPN2_061,15,90631934,C,T,missense_variant(MODERATE|MISSENSE|cGg/cAg|p.Arg140Gln/c.419G>A|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),25729,343,26191,"0,0130961017",0,0,0,0,1,1,0,1,3,NO,NO,COSM41590,haematopoietic_and_lymphoid_tissue,489,NO,rs121913502,YES,"0,0001071",NO,NO,"-3,81",Deleterious,0,Damaging,"29,97","31,99"
"low bq, bad alignment, many samples",UPN2_059,15,90631941,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr138Pro/c.412A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),13500,310,13905,"0,0222941388",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"26,25","14,92"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_060,15,90631941,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr138Pro/c.412A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),18616,407,19123,"0,0212832715",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"26,17","15,11"
"low bq, bad alignment, many samples",UPN2_061,15,90631941,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr138Pro/c.412A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),25025,611,25778,"0,0237023819",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"25,98","15,28"
"low bq, bad alignment, many samples",UPN2_062,15,90631941,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr138Pro/c.412A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),27335,681,28220,"0,0241318214",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"25,53",15
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,15,90631941,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr138Pro/c.412A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),26037,571,26757,"0,02134021",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"26,07","15,42"
"low bq, bad alignment, many samples",UPN2_064,15,90631941,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr138Pro/c.412A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),25154,613,25903,"0,0236652125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"26,08","15,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_065,15,90631941,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr138Pro/c.412A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),12761,274,13092,"0,0209288115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"26,36","14,99"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_066,15,90631941,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr138Pro/c.412A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),11074,247,11393,"0,0216799789",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"26,21","15,87"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_067,15,90631941,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr138Pro/c.412A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),12503,258,12835,"0,0201012855",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"26,37","15,19"
"low bq, bad alignment, many samples",UPN2_068,15,90631941,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr138Pro/c.412A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),15840,414,16376,"0,0252808989",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"25,58","15,39"
"low bq, bad alignment, many samples",UPN2_069,15,90631941,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr138Pro/c.412A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),21530,581,22245,"0,0261182288",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"25,75","15,35"
"low bq, bad alignment, many samples",UPN2_070,15,90631941,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr138Pro/c.412A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),14103,362,14563,"0,0248575156",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"25,57","14,92"
"low bq, bad alignment, many samples",UPN2_071,15,90631941,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr138Pro/c.412A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),16930,389,17424,"0,022325528",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"25,98","15,19"
"low bq, bad alignment, many samples",UPN2_072,15,90631941,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr138Pro/c.412A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),23245,606,24001,"0,025248948",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"26,06","15,63"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,15,90631941,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr138Pro/c.412A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),14992,319,15400,"0,0207142857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"26,31","15,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,15,90631941,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr138Pro/c.412A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),8631,151,8833,"0,0170949847",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"26,07","14,69"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_075,15,90631941,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr138Pro/c.412A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),25316,471,25916,"0,0181741009",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"26,37","15,39"
"low bq, bad alignment, many samples",UPN2_076,15,90631941,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr138Pro/c.412A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),16380,379,16849,"0,0224939166",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"25,79","15,27"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,15,90631941,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr138Pro/c.412A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),16489,369,16952,"0,0217673431",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"25,92","15,69"
"low bq, bad alignment, many samples",UPN2_078,15,90631941,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr138Pro/c.412A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),20634,473,21208,"0,0223029046",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"25,71","15,15"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_079,15,90631941,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr138Pro/c.412A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),12735,266,13050,"0,0203831418",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"26,07","15,26"
"low bq, bad alignment, many samples",UPN2_080,15,90631941,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr138Pro/c.412A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),23350,545,24031,"0,0226790396",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"26,15","15,71"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_081,15,90631941,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr138Pro/c.412A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),27962,599,28737,"0,0208442078",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"26,16","15,23"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_082,15,90631941,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr138Pro/c.412A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),15893,335,16317,"0,0205307348",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"26,26","14,8"
"low bq, bad alignment, many samples",UPN2_083,15,90631941,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr138Pro/c.412A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),23035,617,23764,"0,0259636425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"25,66","15,02"
"low bq, bad alignment, many samples",UPN2_084,15,90631941,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr138Pro/c.412A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),23897,650,24666,"0,0263520636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"25,71","15,18"
"low bq, bad alignment, many samples",UPN2_085,15,90631941,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr138Pro/c.412A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),12488,284,12873,"0,0220616795",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"25,91","15,18"
"low bq, bad alignment, many samples",UPN2_086,15,90631941,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr138Pro/c.412A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),8084,224,8366,"0,0267750418",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"25,73","15,58"
"low bq, bad alignment, many samples",UPN2_087,15,90631941,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr138Pro/c.412A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),21662,496,22274,"0,0222681153",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"26,13","15,48"
"low bq, bad alignment, low freq, many artifacts",UPN2_088,15,90631941,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr138Pro/c.412A>C|452|IDH2|protein_coding|CODING|ENST00000330062|4|G),16661,329,17068,"0,0192758378",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"26,42","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_020,15,90631945,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn136Lys/c.408T>A|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),4690,49,4765,"0,0102833158",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"34,07","18,67"
"low bq, low freq, many artifacts, many samples",UPN2_041,15,90631945,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn136Lys/c.408T>A|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),2491,37,2537,"0,0145841545",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"32,99","17,05"
"low bq, low freq, many artifacts, many samples",UPN2_042,15,90631945,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn136Lys/c.408T>A|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),11090,139,11292,"0,0123095997",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"32,96","17,63"
"low bq, low freq, many artifacts, many samples",UPN2_045,15,90631945,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn136Lys/c.408T>A|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),9475,99,9626,"0,0102846458",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"33,08","16,99"
"low bq, low freq, many artifacts, many samples",UPN2_046,15,90631945,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn136Lys/c.408T>A|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),13412,138,13611,"0,0101388583",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"32,91","16,91"
"low bq, low freq, many artifacts, many samples",UPN2_047,15,90631945,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn136Lys/c.408T>A|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),14646,182,14882,"0,012229539",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"33,03","16,57"
"low bq, low freq, many artifacts, many samples",UPN2_049,15,90631945,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn136Lys/c.408T>A|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),11447,141,11629,"0,0121248603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"32,96","17,65"
"low bq, low freq, many artifacts, many samples",UPN2_050,15,90631945,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn136Lys/c.408T>A|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),9745,121,9898,"0,0122246919",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"32,96","19,21"
"low bq, low freq, many artifacts, many samples",UPN2_051,15,90631945,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn136Lys/c.408T>A|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),10868,124,11047,"0,0112247669",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"32,97","18,37"
"low bq, low freq, many artifacts, many samples",UPN2_052,15,90631945,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn136Lys/c.408T>A|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),8907,106,9050,"0,0117127072",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"33,03","16,32"
"low bq, low freq, many artifacts, many samples",UPN2_053,15,90631945,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn136Lys/c.408T>A|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),12158,145,12351,"0,0117399401",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"33,11","18,25"
"low bq, low freq, many artifacts, many samples",UPN2_054,15,90631945,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn136Lys/c.408T>A|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),7651,109,7785,"0,0140012845",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"32,89","17,26"
"low bq, low freq, many artifacts, many samples",UPN2_055,15,90631945,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn136Lys/c.408T>A|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),12989,148,13191,"0,0112197711",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"33,04","16,73"
"low bq, low freq, many artifacts, many samples",UPN2_057,15,90631945,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn136Lys/c.408T>A|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),12161,141,12346,"0,0114207031",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"33,06","16,96"
"low bq, low freq, many artifacts",UPN2_058,15,90631945,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn136Lys/c.408T>A|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),16984,213,17271,"0,0123328122",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"33,02","17,34"
"many samples, low freq, no database",UPN2_017,15,90631953,T,C,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser134Gly/c.400A>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),3163,36,3210,"0,0112149533",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,81",Deleterious,"0,001",Damaging,"34,82","34,06"
"many samples, low freq, no database",UPN2_018,15,90631953,T,C,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser134Gly/c.400A>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),5578,67,5653,"0,0118521139",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,81",Deleterious,"0,001",Damaging,"34,91","34,84"
"many samples, low freq, no database",UPN2_021,15,90631953,T,C,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser134Gly/c.400A>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),5856,62,5931,"0,0104535491",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,81",Deleterious,"0,001",Damaging,"34,95","34,31"
"many samples, low freq, no database",UPN2_041,15,90631953,T,C,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser134Gly/c.400A>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),2504,28,2539,"0,0110279638",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,81",Deleterious,"0,001",Damaging,"33,57","34,64"
"many samples, low freq, no database",UPN2_024,15,90631953,T,C,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser134Gly/c.400A>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),3472,41,3521,"0,0116444192",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,81",Deleterious,"0,001",Damaging,"34,96","34,73"
"many samples, low freq, no database",UPN2_042,15,90631953,T,C,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser134Gly/c.400A>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),11161,115,11299,"0,0101778918",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,81",Deleterious,"0,001",Damaging,"33,67","33,37"
"low freq, many artifacts, many samples",UPN2_045,15,90631953,T,C,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser134Gly/c.400A>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),9502,98,9632,"0,0101744186",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,81",Deleterious,1,Damaging,"33,68","33,87"
"low freq, many artifacts, many samples",UPN2_046,15,90631953,T,C,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser134Gly/c.400A>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),13423,141,13625,"0,0103486239",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,81",Deleterious,1,Damaging,"33,56","32,65"
"many samples, low freq, no database",UPN2_034,15,90631953,T,C,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser134Gly/c.400A>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),2417,31,2451,"0,0126478988",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,81",Deleterious,"0,001",Damaging,"34,87","33,48"
"many samples, low freq, no database",UPN2_047,15,90631953,T,C,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser134Gly/c.400A>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),14691,150,14891,"0,0100731986",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,81",Deleterious,"0,001",Damaging,"33,78","33,79"
"many samples, low freq, no database",UPN2_048,15,90631953,T,C,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser134Gly/c.400A>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),5624,97,5733,"0,0169195883",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,81",Deleterious,"0,001",Damaging,"33,85","32,99"
"many samples, low freq, no database",UPN2_053,15,90631953,T,C,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser134Gly/c.400A>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),12203,126,12361,"0,0101933501",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,81",Deleterious,"0,001",Damaging,"33,66","33,51"
"many samples, low freq, no database",UPN2_054,15,90631953,T,C,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser134Gly/c.400A>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),7675,98,7792,"0,0125770021",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,81",Deleterious,"0,001",Damaging,"33,63","33,17"
"low freq, many artifacts, many samples",UPN2_070,15,90631953,T,C,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser134Gly/c.400A>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),7259,74,7349,"0,0100693972",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,81",Deleterious,1,Damaging,"33,18","33,2"
"many samples, low freq, no database",UPN2_099,15,90631953,T,C,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser134Gly/c.400A>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),3213,39,3255,"0,0119815668",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,81",Deleterious,"0,001",Damaging,"34,65","34,18"
"inspected, many artifacts",UPN2_036,15,90631958,C,T,stop_gained(HIGH|NONSENSE|tGg/tAg|p.Trp132*/c.395G>A|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),9489,294,9802,"0,0299938788",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,55","33,3"
"low bq, low freq, many artifacts, many samples",UPN2_042,15,90631959,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp132Arg/c.394T>A|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),11120,132,11303,"0,0116783155",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-12,86",Deleterious,0,Damaging,"34,06","22,73"
"low bq, low freq, many artifacts, many samples",UPN2_044,15,90631959,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp132Arg/c.394T>A|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),6537,78,6642,"0,0117434508",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-12,86",Deleterious,0,Damaging,"34,06","20,85"
"low bq, low freq, many artifacts, many samples",UPN2_049,15,90631959,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp132Arg/c.394T>A|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),11457,118,11635,"0,0101418135",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-12,86",Deleterious,0,Damaging,"34,05","20,23"
"low bq, low freq, many artifacts, many samples",UPN2_050,15,90631959,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp132Arg/c.394T>A|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),9760,102,9906,"0,0102967898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-12,86",Deleterious,0,Damaging,"34,03","20,2"
"low bq, low freq, many artifacts, many samples",UPN2_051,15,90631959,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp132Arg/c.394T>A|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),10881,126,11047,"0,0114058115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-12,86",Deleterious,0,Damaging,"34,19","22,05"
"low bq, low freq, many artifacts, many samples",UPN2_053,15,90631959,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp132Arg/c.394T>A|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),12163,147,12363,"0,0118903179",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-12,86",Deleterious,0,Damaging,"33,98","25,23"
"low bq, low freq, many artifacts, many samples",UPN2_054,15,90631959,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp132Arg/c.394T>A|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),7677,82,7793,"0,0105222636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-12,86",Deleterious,0,Damaging,"33,86","24,1"
"low bq, low freq, many artifacts, many samples",UPN2_055,15,90631959,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp132Arg/c.394T>A|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),13007,143,13208,"0,0108267717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-12,86",Deleterious,0,Damaging,"34,02","19,5"
"low bq, low freq, many artifacts, many samples",UPN2_057,15,90631959,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp132Arg/c.394T>A|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),12140,154,12356,"0,0124635804",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-12,86",Deleterious,0,Damaging,"34,07","23,11"
"low bq, low freq, many artifacts",UPN2_058,15,90631959,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp132Arg/c.394T>A|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),17029,180,17278,"0,0104178724",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-12,86",Deleterious,0,Damaging,"34,01","21,97"
"low bq, low freq, many artifacts",UPN2_041,15,90631961,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met131Lys/c.392T>A|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),2496,29,2539,"0,0114218196",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,71",Deleterious,0,Damaging,"33,6","18,45"
"inspected, many artifacts",UPN2_048,15,90631973,T,C,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys127Arg/c.380A>G|452|IDH2|protein_coding|CODING|ENST00000330062|4|C),5650,63,5740,"0,0109756098",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,"0,031",Damaging,"32,24","33,68"
"inspected, many artifacts",UPN2_041,15,90631974,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys127*/c.379A>T|452|IDH2|protein_coding|CODING|ENST00000330062|4|A),2493,30,2540,"0,0118110236",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,48","31,07"
"low bq, low freq, many artifacts",UPN2_034,15,90631977,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe126Ile/c.376T>A|452|IDH2|protein_coding|CODING|ENST00000330062|4|T),2409,28,2449,"0,0114332381",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,58",Deleterious,0,Damaging,"34,1","23,54"
"Not in 2nd illumina, inspected, many artifacts",UPN2_006,17,7572932,C,T,missense_variant(MODERATE|MISSENSE|Gac/Aac|p.Asp393Asn/c.1177G>A|393|TP53|protein_coding|CODING|ENST00000269305|11|T),1123,36,1159,"0,0310612597",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,19",Neutral,"0,001",Damaging,"35,72","35,17"
"inspected, many artifacts",UPN2_044,17,7572947,C,T,missense_variant(MODERATE|MISSENSE|Gaa/Aaa|p.Glu388Lys/c.1162G>A|393|TP53|protein_coding|CODING|ENST00000269305|11|T),1349,23,1373,"0,0167516387",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,"0,007",Damaging,"35,1","35,22"
inspected,UPN2_041,17,7572952,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys386Met/c.1157A>T|393|TP53|protein_coding|CODING|ENST00000269305|11|A),751,44,799,"0,055068836",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,0,Damaging,"35,15","33,91"
"low freq, many artifacts, many samples",UPN2_014,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),4877,63,5001,"0,0125974805",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,52",NA
"low freq, many artifacts, many samples",UPN2_015,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),6385,99,6572,"0,0150639075",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,42",NA
"low freq, many artifacts, many samples",UPN2_016,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),3092,37,3168,"0,0116792929",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,53",NA
"low freq, many artifacts, many samples",UPN2_018,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),2821,50,2908,"0,0171939477",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,47",NA
"low freq, many artifacts, many samples",UPN2_019,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),3041,61,3132,"0,0194763729",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,36",NA
"low freq, many artifacts, many samples",UPN2_020,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),3097,47,3184,"0,0147613065",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,12",NA
"low freq, many artifacts, many samples",UPN2_021,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),3425,40,3507,"0,0114057599",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,44",NA
"low freq, many artifacts, many samples",UPN2_002,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),2099,40,2161,"0,0185099491",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,98",NA
"low freq, many artifacts, many samples",UPN2_022,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),4446,77,4575,"0,0168306011",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,42",NA
"low freq, many artifacts, many samples",UPN2_023,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),4868,89,5027,"0,0177043963",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,48",NA
"low freq, many artifacts, many samples",UPN2_024,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),2566,33,2639,"0,0125047366",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,4",NA
"low freq, many artifacts, many samples",UPN2_025,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),5206,81,5367,"0,0150922303",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,56",NA
"low freq, many artifacts, many samples",UPN2_026,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),5028,63,5162,"0,0122045719",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,39",NA
"low freq, many artifacts, many samples",UPN2_027,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),5554,96,5722,"0,0167773506",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,38",NA
"low freq, many artifacts, many samples",UPN2_089,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),4468,72,4587,"0,0156965337",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,47",NA
"low freq, many artifacts, many samples",UPN2_042,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),7288,98,7471,"0,0131173872",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,23",NA
"low freq, many artifacts, many samples",UPN2_043,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),3580,50,3678,"0,0135943448",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,26",NA
"low freq, many artifacts, many samples",UPN2_029,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),5418,71,5581,"0,0127217345",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,4",NA
"low freq, many artifacts, many samples",UPN2_030,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),5407,83,5557,"0,0149361166",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,34",NA
"low freq, many artifacts, many samples",UPN2_031,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),3175,47,3256,"0,0144348894",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,42",NA
"low freq, many artifacts, many samples",UPN2_045,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),5787,66,5953,"0,011086847",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,07",NA
"low freq, many artifacts, many samples",UPN2_032,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),1946,31,2004,"0,0154690619",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,49",NA
"low freq, many artifacts, many samples",UPN2_046,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),6912,95,7103,"0,0133746304",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,05",NA
"low freq, many artifacts, many samples",UPN2_033,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),3274,50,3366,"0,0148544266",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,46",NA
"low freq, many artifacts, many samples",UPN2_034,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),1612,20,1652,"0,0121065375",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,36",NA
"low freq, many artifacts, many samples",UPN2_047,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),9088,94,9291,"0,0101173178",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,09",NA
"low freq, many artifacts, many samples",UPN2_035,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),5416,88,5582,"0,0157649588",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,49",NA
"low freq, many artifacts, many samples",UPN2_036,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),8925,144,9183,"0,01568115",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,41",NA
"low freq, many artifacts, many samples",UPN2_049,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),6117,88,6281,"0,0140105079",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,26",NA
"low freq, many artifacts, many samples",UPN2_050,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),6330,69,6484,"0,0106415793",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,3",NA
"low freq, many artifacts, many samples",UPN2_037,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),7223,132,7452,"0,0177133655",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,33",NA
"low freq, many artifacts, many samples",UPN2_051,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),5546,78,5707,"0,013667426",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,25",NA
"low freq, many artifacts, many samples",UPN2_052,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),3490,50,3589,"0,0139314572",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,05",NA
"low freq, many artifacts, many samples",UPN2_038,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),8960,130,9222,"0,0140967252",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,47",NA
"low freq, many artifacts, many samples",UPN2_039,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),5369,76,5509,"0,0137956072",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,29",NA
"low freq, many artifacts, many samples",UPN2_053,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),6784,87,6974,"0,0124749068",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,31",NA
"low freq, many artifacts, many samples",UPN2_054,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),3234,43,3326,"0,0129284426",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,29",NA
"low freq, many artifacts, many samples",UPN2_007,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),3755,45,3847,"0,0116974266",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,23",NA
"low freq, many artifacts, many samples",UPN2_008,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),6174,103,6339,"0,0162486197",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,94",NA
"low freq, many artifacts, many samples",UPN2_009,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),5099,87,5257,"0,0165493628",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,91",NA
"low freq, many artifacts, many samples",UPN2_011,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),2651,48,2734,"0,0175566935",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,03",NA
"low freq, many artifacts, many samples",UPN2_055,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),6872,91,7054,"0,012900482",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,18",NA
many samples,UPN2_056,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),2384,57,2464,"0,0231331169",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,34",NA
"low freq, many artifacts, many samples",UPN2_090,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),3142,45,3208,"0,0140274314",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,5",NA
"low freq, many artifacts, many samples",UPN2_057,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),5673,74,5824,"0,012706044",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,07",NA
"low freq, many artifacts, many samples",UPN2_058,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),10664,181,11014,"0,0164336299",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,24",NA
"low freq, many artifacts, many samples",UPN2_059,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),2662,42,2734,"0,0153621068",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,41",NA
"low freq, many artifacts, many samples",UPN2_012,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),1905,26,1954,"0,0133060389",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,76",NA
"low freq, many artifacts, many samples",UPN2_060,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),3256,52,3340,"0,0155688623",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,31",NA
"low freq, many artifacts, many samples",UPN2_040,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),4001,50,4091,"0,0122219506",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,36",NA
"low freq, many artifacts, many samples",UPN2_013,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),1264,20,1298,"0,0154083205",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,05",NA
"low freq, many artifacts, many samples",UPN2_091,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),3536,57,3634,"0,0156851954",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,42",NA
"low freq, many artifacts, many samples",UPN2_092,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),2141,25,2185,"0,0114416476",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,48",NA
"low freq, many artifacts, many samples",UPN2_093,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),2590,35,2647,"0,0132225161",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,63",NA
"low freq, many artifacts, many samples",UPN2_061,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),3429,41,3518,"0,0116543491",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,32",NA
"low freq, many artifacts, many samples",UPN2_062,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),3224,55,3328,"0,0165264423",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,17",NA
"low freq, many artifacts, many samples",UPN2_063,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),3772,48,3864,"0,0124223602",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,26",NA
"low freq, many artifacts, many samples",UPN2_064,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),4517,69,4640,"0,0148706897",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,2",NA
"low freq, many artifacts, many samples",UPN2_065,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),2611,39,2693,"0,0144819903",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,29",NA
"low freq, many artifacts, many samples",UPN2_066,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),2708,42,2787,"0,0150699677",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,31",NA
"low freq, many artifacts, many samples",UPN2_067,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),2487,28,2547,"0,0109933255",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,39",NA
"low freq, many artifacts, many samples",UPN2_068,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),2818,33,2880,"0,0114583333",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,09",NA
"low freq, many artifacts, many samples",UPN2_069,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),3448,43,3536,"0,0121606335",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,19",NA
"low freq, many artifacts, many samples",UPN2_070,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),2405,28,2466,"0,0113544201",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,21",NA
"low freq, many artifacts, many samples",UPN2_071,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),3703,70,3817,"0,0183390097",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,15",NA
"low freq, many artifacts, many samples",UPN2_072,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),3967,65,4099,"0,0158575262",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,22",NA
"low freq, many artifacts, many samples",UPN2_073,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),2759,44,2847,"0,0154548648",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,28",NA
"low freq, many artifacts, many samples",UPN2_074,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),2297,41,2359,"0,0173802459",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,27",NA
"low freq, many artifacts, many samples",UPN2_075,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),6449,80,6617,"0,012090071",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,6",NA
"low freq, many artifacts, many samples",UPN2_076,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),2576,39,2651,"0,0147114296",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,44",NA
"low freq, many artifacts, many samples",UPN2_077,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),2050,29,2107,"0,013763645",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,13",NA
"low freq, many artifacts, many samples",UPN2_078,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),4256,55,4361,"0,0126117863",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,18",NA
"low freq, many artifacts, many samples",UPN2_079,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),2296,38,2371,"0,0160269928",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,45",NA
"low freq, many artifacts, many samples",UPN2_080,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),3672,43,3768,"0,0114118896",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,2",NA
"low freq, many artifacts, many samples",UPN2_081,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),4840,75,4986,"0,0150421179",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,21",NA
"low freq, many artifacts, many samples",UPN2_082,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),3813,56,3923,"0,0142747897",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,22",NA
"low freq, many artifacts, many samples",UPN2_083,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),3429,47,3525,"0,0133333333",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,3",NA
"low freq, many artifacts, many samples",UPN2_084,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),3600,48,3698,"0,0129799892",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,33",NA
"low freq, many artifacts, many samples",UPN2_085,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),3479,61,3579,"0,017043867",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,28",NA
many samples,UPN2_086,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),1867,44,1944,"0,0226337449",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,21",NA
"low freq, many artifacts, many samples",UPN2_087,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),5138,65,5283,"0,0123036154",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,27",NA
"low freq, many artifacts, many samples",UPN2_088,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),2700,40,2781,"0,0143833154",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,37",NA
"low freq, many artifacts, many samples",UPN2_094,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),4457,62,4573,"0,0135578395",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,5",NA
"low freq, many artifacts, many samples",UPN2_095,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),3389,48,3475,"0,0138129496",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,46",NA
"low freq, many artifacts, many samples",UPN2_096,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),4401,59,4502,"0,0131052865",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,4",NA
"low freq, many artifacts, many samples",UPN2_097,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),4757,74,4871,"0,0151919524",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,49",NA
"low freq, many artifacts, many samples",UPN2_098,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),3251,56,3340,"0,0167664671",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,67",NA
"low freq, many artifacts, many samples",UPN2_100,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),3932,61,4029,"0,0151402333",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,64",NA
"low freq, many artifacts, many samples",UPN2_101,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),3229,33,3299,"0,0100030312",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,44",NA
"low freq, many artifacts, many samples",UPN2_102,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),3465,37,3556,"0,0104049494",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,51",NA
"low freq, many artifacts, many samples",UPN2_103,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),3892,46,3969,"0,0115898211",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,41",NA
"low freq, many artifacts, many samples",UPN2_104,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),4851,76,4966,"0,0153040677",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,46",NA
"low freq, many artifacts, many samples",UPN2_105,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),4148,58,4246,"0,0136599152",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,53",NA
"low freq, many artifacts, many samples",UPN2_106,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),5279,69,5401,"0,012775412",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,57",NA
"low freq, many artifacts, many samples",UPN2_107,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),6681,90,6840,"0,0131578947",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,54",NA
"low freq, many artifacts, many samples",UPN2_108,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),5944,89,6087,"0,0146213241",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,56",NA
"low freq, many artifacts, many samples",UPN2_109,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),5150,70,5275,"0,0132701422",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,47",NA
"low freq, many artifacts, many samples",UPN2_110,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),5761,88,5897,"0,0149228421",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,48",NA
"low freq, many artifacts",UPN2_111,17,7572962,GT,G,frameshift_variant(HIGH||aaa/|p.Lys382fs/c.1146delA|393|TP53|protein_coding|CODING|ENST00000269305|11|G),4254,57,4361,"0,0130703967",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,44",NA
"low freq, many artifacts, many samples",UPN2_045,17,7572963,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys382Asn/c.1146A>C|393|TP53|protein_coding|CODING|ENST00000269305|11|G),5787,61,5953,"0,0102469343",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,23,Damaging,"34,07",32
"low freq, many artifacts, many samples",UPN2_066,17,7572963,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys382Asn/c.1146A>C|393|TP53|protein_coding|CODING|ENST00000269305|11|G),2708,30,2787,"0,0107642626",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,23,Damaging,"33,31","30,83"
"low freq, many artifacts, many samples",UPN2_072,17,7572963,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys382Asn/c.1146A>C|393|TP53|protein_coding|CODING|ENST00000269305|11|G),3967,44,4099,"0,0107343254",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,23,Damaging,"33,22","29,84"
"low freq, many artifacts",UPN2_102,17,7572963,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys382Asn/c.1146A>C|393|TP53|protein_coding|CODING|ENST00000269305|11|G),3465,41,3556,"0,0115298088",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,23,Damaging,"34,51","30,98"
"Not in 2nd illumina, inspected, many artifacts",UPN2_006,17,7572985,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln375Leu/c.1124A>T|393|TP53|protein_coding|CODING|ENST00000269305|11|A),2259,25,2288,"0,0109265734",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,"0,062",Tolerated,"34,1","29,72"
"Not in 2nd illumina, inspected, many artifacts",UPN2_006,17,7572990,CT,C,frameshift_variant(HIGH||aag/|p.Lys373fs/c.1118delA|393|TP53|protein_coding|CODING|ENST00000269305|11|C),2192,92,2297,"0,0400522421",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,79",NA
"inspected, many artifacts",UPN2_012,17,7572994,T,C,missense_variant(MODERATE|MISSENSE|aAa/aGa|p.Lys372Arg/c.1115A>G|393|TP53|protein_coding|CODING|ENST00000269305|11|C),3821,46,3880,"0,0118556701",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,19",Neutral,"0,066",Tolerated,"34,25","32,57"
"inspected, many artifacts",UPN2_011,17,7573004,G,T,missense_variant(MODERATE|MISSENSE|Ctg/Atg|p.Leu369Met/c.1105C>A|393|TP53|protein_coding|CODING|ENST00000269305|11|T),5363,68,5431,"0,0125207144",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,"0,042",Damaging,"34,45","30,96"
inspected,UPN2_056,17,7573927,C,T,missense_variant(MODERATE|MISSENSE|aGc/aAc|p.Ser367Asn/c.1100G>A|393|TP53|protein_coding|CODING|ENST00000269305|10|T),1326,26,1352,"0,0192307692",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,064",Tolerated,"35,63",35
"inspected, many artifacts",UPN2_012,17,7573942,C,T,missense_variant(MODERATE|MISSENSE|aGc/aAc|p.Ser362Asn/c.1085G>A|393|TP53|protein_coding|CODING|ENST00000269305|10|T),1870,30,1900,"0,0157894737",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,195",Tolerated,"35,76","35,27"
"many samples, homopolymer 6C, low freq, ins and del",UPN2_035,17,7573943,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Ser362fs/c.1083dupG|393|TP53|protein_coding|CODING|ENST00000269305|10|TC),3674,59,3698,"0,01595457",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,77",NA
"many samples, homopolymer 6C, low freq, ins and del",UPN2_039,17,7573943,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Ser362fs/c.1083dupG|393|TP53|protein_coding|CODING|ENST00000269305|10|TC),3496,54,3518,"0,0153496305",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,76",NA
"many samples, homopolymer 6C, low freq, ins and del",UPN2_040,17,7573943,T,TC,frameshift_variant(HIGH||ggg/gggG|p.Ser362fs/c.1083dupG|393|TP53|protein_coding|CODING|ENST00000269305|10|TC),2265,38,2282,"0,0166520596",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,74",NA
"many samples, homopolymer 6C, low freq, ins and del",UPN2_061,17,7573943,TC,T,frameshift_variant(HIGH||ggg/|p.Ser362fs/c.1083delG|393|TP53|protein_coding|CODING|ENST00000269305|10|T),3649,37,3694,"0,0100162426",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,31",NA
"many samples, homopolymer 6C, low freq, ins and del",UPN2_108,17,7573943,TC,T,frameshift_variant(HIGH||ggg/|p.Ser362fs/c.1083delG|393|TP53|protein_coding|CODING|ENST00000269305|10|T),3122,34,3170,"0,0107255521",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,65",NA
"Not in 2nd illumina, inspected, many artifacts",UPN2_006,17,7573978,A,T,missense_variant(MODERATE|MISSENSE|cTc/cAc|p.Leu350His/c.1049T>A|393|TP53|protein_coding|CODING|ENST00000269305|10|T),697,55,754,"0,0729442971",0,0,0,1,1,0,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,0,Damaging,"33,89","35,53"
"low bq, low freq, many artifacts, many samples",UPN2_071,17,7573996,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu344Arg/c.1031T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),2986,37,3040,"0,0121710526",0,0,0,0,1,0,0,0,1,NO,NO,COSM46303. COSM323924,lung. urinary_tract,"2,1",NO,NO,NO,NO,NO,NO,"-4,38",Deleterious,13,Damaging,"30,42","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_078,17,7573996,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu344Arg/c.1031T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),3998,41,4058,"0,0101034993",0,0,0,0,1,0,0,0,1,NO,NO,COSM46303. COSM323924,lung. urinary_tract,"2,1",NO,NO,NO,NO,NO,NO,"-4,38",Deleterious,13,Damaging,"30,23","15,78"
"low bq, low freq, many artifacts, many samples",UPN2_080,17,7573996,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu344Arg/c.1031T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),3344,38,3399,"0,0111797588",0,0,0,0,1,0,0,0,1,NO,NO,COSM46303. COSM323924,lung. urinary_tract,"2,1",NO,NO,NO,NO,NO,NO,"-4,38",Deleterious,13,Damaging,"30,32","16,11"
"inspected, many artifacts, ins and del",UPN2_022,17,7574002,CG,C,frameshift_variant(HIGH||cga/|p.Arg342fs/c.1024delC|393|TP53|protein_coding|CODING|ENST00000269305|10|C),4835,796,5652,"0,1408351026",1,1,0,1,0,1,0,1,5,NA,NA,NO,NO,NO,NA,NA,NO,NO,NO,NO,NA,NA,NA,NA,"33,32",NA
inspected,UPN2_044,17,7574003,G,C,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg342Gly/c.1024C>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),3177,150,3343,"0,0448698774",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,09",Deleterious,"0,058",Tolerated,"32,93","31,83"
"low bq, low freq, many artifacts, many samples",UPN2_062,17,7574006,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe341Val/c.1021T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),7492,83,7614,"0,0109009719",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,5,Damaging,"28,03","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_063,17,7574006,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe341Val/c.1021T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),6681,73,6797,"0,0107400324",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,5,Damaging,"28,55","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_066,17,7574006,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe341Val/c.1021T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),3259,42,3340,"0,0125748503",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,5,Damaging,"28,44","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_068,17,7574006,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe341Val/c.1021T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),4892,50,4964,"0,0100725222",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,5,Damaging,"27,98","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_069,17,7574006,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe341Val/c.1021T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),6024,67,6118,"0,0109512913",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,5,Damaging,"28,32","15,69"
"low bq, low freq, many artifacts, many samples",UPN2_070,17,7574006,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe341Val/c.1021T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),4397,46,4482,"0,0102632753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,5,Damaging,"28,19","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_071,17,7574006,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe341Val/c.1021T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),5704,64,5789,"0,01105545",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,5,Damaging,"28,43","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_074,17,7574006,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe341Val/c.1021T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),3175,33,3221,"0,0102452654",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,5,Damaging,"28,54","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_076,17,7574006,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe341Val/c.1021T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),4572,48,4645,"0,0103336921",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,5,Damaging,"28,26","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_080,17,7574006,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe341Val/c.1021T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),6450,75,6561,"0,0114311843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,5,Damaging,"28,3","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_081,17,7574006,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe341Val/c.1021T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),8397,89,8516,"0,0104509159",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,5,Damaging,"28,5","20,02"
"low bq, low freq, many artifacts, many samples",UPN2_082,17,7574006,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe341Val/c.1021T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),5186,63,5268,"0,0119589977",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,5,Damaging,"28,54","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_083,17,7574006,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe341Val/c.1021T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),6496,70,6602,"0,0106028476",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,5,Damaging,"28,07","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_084,17,7574006,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe341Val/c.1021T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),7677,80,7798,"0,0102590408",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,5,Damaging,"28,16","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_085,17,7574006,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe341Val/c.1021T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),3692,41,3758,"0,0109100585",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,5,Damaging,"28,42","14,8"
"low bq, low freq, many artifacts",UPN2_087,17,7574006,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe341Val/c.1021T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),5967,63,6070,"0,0103789127",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,5,Damaging,"28,47","14,79"
low freq,UPN2_092,17,7574012,C,T,missense_variant(MODERATE|MISSENSE|Gag/Aag|p.Glu339Lys/c.1015G>A|393|TP53|protein_coding|CODING|ENST00000269305|10|T),2360,24,2388,"0,0100502513",0,0,0,0,1,0,0,1,2,NO,NO,COSM46153,upper_aerodigestive_tract,1,rs17882252,rs17882252,NO,"6,59E-005",NO,NO,"-3,01",Deleterious,"0,032",Damaging,"32,28","33,29"
"low bq, low freq, many artifacts, many samples",UPN2_063,17,7574014,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe338Cys/c.1013T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),6692,68,6798,"0,010002942",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-5,Deleterious,0,Damaging,"30,05","16,07"
"low bq, low freq, many artifacts, many samples",UPN2_065,17,7574014,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe338Cys/c.1013T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),3188,34,3234,"0,0105132962",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-5,Deleterious,0,Damaging,"30,02","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_072,17,7574014,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe338Cys/c.1013T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),6219,65,6299,"0,0103190983",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-5,Deleterious,0,Damaging,"29,84","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_077,17,7574014,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe338Cys/c.1013T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),5440,56,5534,"0,0101192627",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-5,Deleterious,0,Damaging,"29,84","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_086,17,7574014,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe338Cys/c.1013T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),2471,26,2514,"0,0103420843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-5,Deleterious,0,Damaging,"29,75","15,54"
"low bq, low freq, many artifacts",UPN2_088,17,7574014,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe338Cys/c.1013T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),4556,47,4623,"0,0101665585",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-5,Deleterious,0,Damaging,"30,04","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_059,17,7574015,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe338Val/c.1012T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),3479,59,3555,"0,0165963432",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,14",Deleterious,1,Damaging,"29,21","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_060,17,7574015,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe338Val/c.1012T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),5855,94,5982,"0,0157138081",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,14",Deleterious,1,Damaging,"29,5","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_061,17,7574015,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe338Val/c.1012T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),7191,124,7343,"0,016886831",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,14",Deleterious,1,Damaging,"29,16","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_062,17,7574015,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe338Val/c.1012T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),7465,129,7615,"0,0169402495",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,14",Deleterious,1,Damaging,"29,12","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_063,17,7574015,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe338Val/c.1012T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),6656,120,6799,"0,0176496544",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,14",Deleterious,1,Damaging,"29,31","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_064,17,7574015,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe338Val/c.1012T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),7130,122,7271,"0,016778985",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,14",Deleterious,1,Damaging,"29,33","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_065,17,7574015,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe338Val/c.1012T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),3153,65,3235,"0,0200927357",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,14",Deleterious,1,Damaging,"29,33","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_066,17,7574015,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe338Val/c.1012T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),3272,45,3341,"0,0134690213",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,14",Deleterious,1,Damaging,"29,48","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_067,17,7574015,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe338Val/c.1012T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),3698,66,3777,"0,0174741859",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,14",Deleterious,1,Damaging,"29,36","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_068,17,7574015,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe338Val/c.1012T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),4855,82,4965,"0,0165156093",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,14",Deleterious,1,Damaging,"28,97","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_069,17,7574015,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe338Val/c.1012T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),5972,113,6121,"0,0184610358",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,14",Deleterious,1,Damaging,"29,33","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_070,17,7574015,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe338Val/c.1012T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),4378,84,4485,"0,018729097",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,14",Deleterious,1,Damaging,"28,95","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_071,17,7574015,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe338Val/c.1012T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),5676,89,5792,"0,0153660221",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,14",Deleterious,1,Damaging,"29,23","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_072,17,7574015,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe338Val/c.1012T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),6177,96,6299,"0,0152405144",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,14",Deleterious,1,Damaging,"29,33","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_073,17,7574015,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe338Val/c.1012T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),5068,88,5170,"0,0170212766",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,14",Deleterious,1,Damaging,"29,37","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_074,17,7574015,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe338Val/c.1012T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),3147,61,3223,"0,018926466",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,14",Deleterious,1,Damaging,"29,11","15,49"
"low bq, low freq, many artifacts, many samples",UPN2_075,17,7574015,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe338Val/c.1012T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),7768,124,7938,"0,0156210632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,14",Deleterious,1,Damaging,"29,68","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_076,17,7574015,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe338Val/c.1012T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),4552,81,4649,"0,0174231017",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,14",Deleterious,1,Damaging,"29,17","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_077,17,7574015,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe338Val/c.1012T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),5424,89,5533,"0,0160853063",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,14",Deleterious,1,Damaging,"29,23","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_078,17,7574015,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe338Val/c.1012T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),7729,126,7877,"0,0159959375",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,14",Deleterious,1,Damaging,"28,98","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_079,17,7574015,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe338Val/c.1012T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),4509,93,4623,"0,0201168073",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,14",Deleterious,1,Damaging,"29,33","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_080,17,7574015,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe338Val/c.1012T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),6419,114,6562,"0,0173727522",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,14",Deleterious,1,Damaging,"29,03","15,6"
"low bq, low freq, many artifacts, many samples",UPN2_081,17,7574015,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe338Val/c.1012T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),8361,114,8515,"0,0133881386",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,14",Deleterious,1,Damaging,"29,49","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_082,17,7574015,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe338Val/c.1012T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),5190,67,5271,"0,0127110605",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,14",Deleterious,1,Damaging,"29,52","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_083,17,7574015,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe338Val/c.1012T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),6467,101,6604,"0,0152937614",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,14",Deleterious,1,Damaging,"29,04","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_084,17,7574015,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe338Val/c.1012T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),7645,123,7801,"0,0157672093",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,14",Deleterious,1,Damaging,"29,14","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_085,17,7574015,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe338Val/c.1012T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),3688,60,3759,"0,0159616919",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,14",Deleterious,1,Damaging,"29,38","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_086,17,7574015,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe338Val/c.1012T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),2465,33,2514,"0,0131264916",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,14",Deleterious,1,Damaging,"28,99","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_087,17,7574015,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe338Val/c.1012T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),5925,108,6073,"0,0177836325",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,14",Deleterious,1,Damaging,"29,21","14,23"
"low bq, low freq, many artifacts",UPN2_088,17,7574015,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe338Val/c.1012T>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),4532,62,4623,"0,0134112048",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,14",Deleterious,1,Damaging,"29,49","14,98"
"inspected, many artifacts",UPN2_048,17,7574020,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu336Gly/c.1007A>G|393|TP53|protein_coding|CODING|ENST00000269305|10|C),1974,40,2024,"0,0197628458",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,64",Deleterious,"0,023",Damaging,"32,33","31,35"
"inspected, many artifacts",UPN2_044,17,7574024,G,A,missense_variant(MODERATE|MISSENSE|Cgt/Tgt|p.Arg335Cys/c.1003C>T|393|TP53|protein_coding|CODING|ENST00000269305|10|A),3306,34,3347,"0,0101583508",0,0,0,0,1,0,0,1,2,"0,0116",NO,NO,NA,NA,NO,rs375444154,NO,NO,NO,NO,"-6,84",Deleterious,0,Damaging,"33,64","27,59"
"inspected, many artifacts",UPN2_090,17,7574024,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg335Ser/c.1003C>A|393|TP53|protein_coding|CODING|ENST00000269305|10|T),2907,71,2982,"0,0238095238",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,0,Damaging,"33,45","33,44"
"inspected, many artifacts",UPN2_048,17,7574030,G,A,missense_variant(MODERATE|MISSENSE|Cgt/Tgt|p.Arg333Cys/c.997C>T|393|TP53|protein_coding|CODING|ENST00000269305|10|A),1978,31,2026,"0,0153010859",0,0,0,0,1,0,0,1,2,NO,NO,"COSM4384911, COSM4384912",haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NA,NO,NO,"-5,56",Deleterious,0,Damaging,"33,54","35,26"
"inspected, many artifacts",UPN2_093,17,7574030,G,A,missense_variant(MODERATE|MISSENSE|Cgt/Tgt|p.Arg333Cys/c.997C>T|393|TP53|protein_coding|CODING|ENST00000269305|10|A),2576,32,2616,"0,0122324159",0,0,0,0,1,0,0,1,2,NO,NO,"COSM4384911, COSM4384912",haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NA,NO,NO,"-5,56",Deleterious,0,Damaging,"32,06","34,91"
"inspected, many artifacts",UPN2_090,17,7576870,C,A,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu326*/c.976G>T|393|TP53|protein_coding|CODING|ENST00000269305|9|A),1698,20,1720,"0,011627907",0,0,0,0,1,0,0,1,2,NO,NO,"COSM11570, COSM2744454, COSM3723941, COSM2744453","large_intestine, oesophagus, skin, upper_aerodigestive_tract","1, 1, 1, 4",NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,21","33,6"
"low freq, many artifacts",UPN2_044,17,7576921,G,A,missense_variant(MODERATE|MISSENSE|Ccc/Tcc|p.Pro309Ser/c.925C>T|393|TP53|protein_coding|CODING|ENST00000269305|9|A),3836,46,3884,"0,0118434604",0,0,0,0,1,0,0,0,1,NO,NO,COSM1679488. COSM4271721. COSM11677. COSM1679489,large_intestine. upper_aerodigestive_tract,"12,1",NO,NO,NO,NO,NO,NO,"0,18",Neutral,296,Tolerated,"35,26","34,72"
"inspected, bad alignment, many artifacts",UPN2_056,17,7577030,C,T,missense_variant(MODERATE|MISSENSE|aGc/aAc|p.Ser303Asn/c.908G>A|393|TP53|protein_coding|CODING|ENST00000269305|8|T),1983,45,2033,"0,0221347762",0,0,0,0,1,1,0,1,3,NO,NO,COSM43986,"breast, large_intestine, urinary_tract","1, 1, 1",NO,NO,NO,NO,NO,NO,"-0,39",Neutral,"0,059",Tolerated,"31,19","32,51"
"inspected, bad alignment, many artifacts",UPN2_056,17,7577031,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser303Gly/c.907A>G|393|TP53|protein_coding|CODING|ENST00000269305|8|C),2006,30,2040,"0,0147058824",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,62",Neutral,"0,488",Tolerated,"32,09","29,03"
"inspected, bad alignment, many artifacts",UPN2_056,17,7577035,TG,T,frameshift_variant(HIGH||cca/|p.Pro301fs/c.902delC|393|TP53|protein_coding|CODING|ENST00000269305|8|T),2007,30,2048,"0,0146484375",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,23",NA
"low bq, low freq, many artifacts, many samples",UPN2_059,17,7577045,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu298Ala/c.893A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),5236,69,5329,"0,0129480203",0,0,0,0,1,0,0,0,1,NO,NO,COSM45127,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,162,Tolerated,"28,71","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_060,17,7577045,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu298Ala/c.893A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),18149,239,18459,"0,0129476136",0,0,0,0,1,0,0,0,1,NO,NO,COSM45127,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,162,Tolerated,"28,74","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_061,17,7577045,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu298Ala/c.893A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),20377,258,20714,"0,0124553442",0,0,0,0,1,0,0,0,1,NO,NO,COSM45127,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,162,Tolerated,"28,69","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_062,17,7577045,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu298Ala/c.893A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),22954,293,23347,"0,0125497923",0,0,0,0,1,0,0,0,1,NO,NO,COSM45127,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,162,Tolerated,"28,68","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_063,17,7577045,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu298Ala/c.893A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),22277,270,22632,"0,0119300106",0,0,0,0,1,0,0,0,1,NO,NO,COSM45127,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,162,Tolerated,"28,64","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_064,17,7577045,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu298Ala/c.893A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),10275,145,10461,"0,0138610076",0,0,0,0,1,0,0,0,1,NO,NO,COSM45127,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,162,Tolerated,"28,68","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_065,17,7577045,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu298Ala/c.893A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),9854,124,10013,"0,0123839009",0,0,0,0,1,0,0,0,1,NO,NO,COSM45127,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,162,Tolerated,"28,67","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_066,17,7577045,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu298Ala/c.893A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),16848,215,17119,"0,0125591448",0,0,0,0,1,0,0,0,1,NO,NO,COSM45127,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,162,Tolerated,"28,68","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_067,17,7577045,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu298Ala/c.893A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),16735,226,17014,"0,0132831786",0,0,0,0,1,0,0,0,1,NO,NO,COSM45127,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,162,Tolerated,"28,73","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_068,17,7577045,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu298Ala/c.893A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),17191,213,17468,"0,0121937257",0,0,0,0,1,0,0,0,1,NO,NO,COSM45127,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,162,Tolerated,"28,65","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_069,17,7577045,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu298Ala/c.893A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),18988,252,19305,"0,0130536131",0,0,0,0,1,0,0,0,1,NO,NO,COSM45127,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,162,Tolerated,"28,72","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_070,17,7577045,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu298Ala/c.893A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),12570,175,12800,"0,013671875",0,0,0,0,1,0,0,0,1,NO,NO,COSM45127,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,162,Tolerated,"28,81","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_071,17,7577045,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu298Ala/c.893A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),15628,188,15916,"0,0118120131",0,0,0,0,1,0,0,0,1,NO,NO,COSM45127,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,162,Tolerated,"28,68","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_072,17,7577045,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu298Ala/c.893A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),17711,225,18017,"0,0124882056",0,0,0,0,1,0,0,0,1,NO,NO,COSM45127,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,162,Tolerated,"28,71","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_073,17,7577045,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu298Ala/c.893A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),9575,141,9750,"0,0144615385",0,0,0,0,1,0,0,0,1,NO,NO,COSM45127,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,162,Tolerated,"28,76","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_074,17,7577045,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu298Ala/c.893A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),11128,170,11334,"0,0149991177",0,0,0,0,1,0,0,0,1,NO,NO,COSM45127,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,162,Tolerated,"28,84","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_075,17,7577045,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu298Ala/c.893A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),24232,342,24693,"0,013850079",0,0,0,0,1,0,0,0,1,NO,NO,COSM45127,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,162,Tolerated,"28,78","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_076,17,7577045,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu298Ala/c.893A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),15139,198,15422,"0,0128388017",0,0,0,0,1,0,0,0,1,NO,NO,COSM45127,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,162,Tolerated,"28,76","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_077,17,7577045,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu298Ala/c.893A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),16556,239,16879,"0,0141596066",0,0,0,0,1,0,0,0,1,NO,NO,COSM45127,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,162,Tolerated,"28,71","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_078,17,7577045,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu298Ala/c.893A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),19063,244,19390,"0,0125838061",0,0,0,0,1,0,0,0,1,NO,NO,COSM45127,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,162,Tolerated,"28,71","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_079,17,7577045,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu298Ala/c.893A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),11248,144,11449,"0,0125775177",0,0,0,0,1,0,0,0,1,NO,NO,COSM45127,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,162,Tolerated,"28,72","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_080,17,7577045,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu298Ala/c.893A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),15905,196,16167,"0,0121234614",0,0,0,0,1,0,0,0,1,NO,NO,COSM45127,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,162,Tolerated,"28,71","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_081,17,7577045,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu298Ala/c.893A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),10323,129,10492,"0,012295082",0,0,0,0,1,0,0,0,1,NO,NO,COSM45127,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,162,Tolerated,"28,68","14,2"
"low bq, low freq, many artifacts, many samples",UPN2_082,17,7577045,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu298Ala/c.893A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),15952,176,16190,"0,010870908",0,0,0,0,1,0,0,0,1,NO,NO,COSM45127,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,162,Tolerated,"28,76","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_083,17,7577045,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu298Ala/c.893A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),21267,305,21647,"0,0140897122",0,0,0,0,1,0,0,0,1,NO,NO,COSM45127,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,162,Tolerated,"28,7","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_084,17,7577045,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu298Ala/c.893A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),21840,287,22195,"0,0129308403",0,0,0,0,1,0,0,0,1,NO,NO,COSM45127,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,162,Tolerated,"28,73","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_085,17,7577045,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu298Ala/c.893A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),12382,152,12579,"0,0120836314",0,0,0,0,1,0,0,0,1,NO,NO,COSM45127,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,162,Tolerated,"28,8","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_086,17,7577045,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu298Ala/c.893A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),9023,116,9177,"0,0126402964",0,0,0,0,1,0,0,0,1,NO,NO,COSM45127,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,162,Tolerated,"28,7","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_087,17,7577045,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu298Ala/c.893A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),19989,266,20331,"0,0130834686",0,0,0,0,1,0,0,0,1,NO,NO,COSM45127,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,162,Tolerated,"28,54","14,42"
"low bq, low freq, many artifacts",UPN2_088,17,7577045,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu298Ala/c.893A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),16163,230,16454,"0,0139783639",0,0,0,0,1,0,0,0,1,NO,NO,COSM45127,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,162,Tolerated,"28,73","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_059,17,7577048,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His297Pro/c.890A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),5230,63,5330,"0,0118198874",0,0,0,0,1,0,0,0,1,NO,NO,COSM45478,cervix,1,NO,NO,NO,NO,NO,NO,"0,12",Neutral,1,Tolerated,"28,88","14,11"
"low bq, low freq, many artifacts, many samples",UPN2_060,17,7577048,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His297Pro/c.890A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),18118,201,18449,"0,0108948995",0,0,0,0,1,0,0,0,1,NO,NO,COSM45478,cervix,1,NO,NO,NO,NO,NO,NO,"0,12",Neutral,1,Tolerated,"28,84","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_062,17,7577048,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His297Pro/c.890A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),22894,239,23339,"0,0102403702",0,0,0,0,1,0,0,0,1,NO,NO,COSM45478,cervix,1,NO,NO,NO,NO,NO,NO,"0,12",Neutral,1,Tolerated,"28,83","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_065,17,7577048,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His297Pro/c.890A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),9819,102,10008,"0,0101918465",0,0,0,0,1,0,0,0,1,NO,NO,COSM45478,cervix,1,NO,NO,NO,NO,NO,NO,"0,12",Neutral,1,Tolerated,"28,94","15,62"
"low bq, low freq, many artifacts, many samples",UPN2_066,17,7577048,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His297Pro/c.890A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),16832,173,17116,"0,0101075018",0,0,0,0,1,0,0,0,1,NO,NO,COSM45478,cervix,1,NO,NO,NO,NO,NO,NO,"0,12",Neutral,1,Tolerated,"28,83","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_069,17,7577048,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His297Pro/c.890A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),18974,194,19303,"0,0100502513",0,0,0,0,1,0,0,0,1,NO,NO,COSM45478,cervix,1,NO,NO,NO,NO,NO,NO,"0,12",Neutral,1,Tolerated,"28,85","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_072,17,7577048,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His297Pro/c.890A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),17697,185,18016,"0,0102686501",0,0,0,0,1,0,0,0,1,NO,NO,COSM45478,cervix,1,NO,NO,NO,NO,NO,NO,"0,12",Neutral,1,Tolerated,"28,84","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_074,17,7577048,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His297Pro/c.890A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),11127,117,11329,"0,0103274782",0,0,0,0,1,0,0,0,1,NO,NO,COSM45478,cervix,1,NO,NO,NO,NO,NO,NO,"0,12",Neutral,1,Tolerated,"28,89","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_076,17,7577048,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His297Pro/c.890A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),15163,159,15421,"0,0103106154",0,0,0,0,1,0,0,0,1,NO,NO,COSM45478,cervix,1,NO,NO,NO,NO,NO,NO,"0,12",Neutral,1,Tolerated,"28,85","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_077,17,7577048,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His297Pro/c.890A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),16566,175,16869,"0,0103740589",0,0,0,0,1,0,0,0,1,NO,NO,COSM45478,cervix,1,NO,NO,NO,NO,NO,NO,"0,12",Neutral,1,Tolerated,"28,8","14,86"
"low bq, low freq, many artifacts",UPN2_086,17,7577048,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His297Pro/c.890A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),9006,95,9177,"0,0103519669",0,0,0,0,1,0,0,0,1,NO,NO,COSM45478,cervix,1,NO,NO,NO,NO,NO,NO,"0,12",Neutral,1,Tolerated,"28,92","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_059,17,7577051,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His296Pro/c.887A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),5172,111,5311,"0,0209000188",0,0,0,0,1,0,0,0,1,NO,NO,COSM43858,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,279,Tolerated,"28,79","15,36"
"low bq, many samples",UPN2_060,17,7577051,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His296Pro/c.887A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),17872,424,18394,"0,0230509949",0,0,0,0,1,0,0,0,1,NO,NO,COSM43858,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,279,Tolerated,"28,52","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_061,17,7577051,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His296Pro/c.887A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),20105,409,20627,"0,0198283803",0,0,0,0,1,0,0,0,1,NO,NO,COSM43858,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,279,Tolerated,"28,52","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_062,17,7577051,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His296Pro/c.887A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),22615,506,23274,"0,0217409985",0,0,0,0,1,0,0,0,1,NO,NO,COSM43858,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,279,Tolerated,"28,51","14,92"
"low bq, many samples",UPN2_063,17,7577051,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His296Pro/c.887A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),21933,506,22571,"0,0224181472",0,0,0,0,1,0,0,0,1,NO,NO,COSM43858,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,279,Tolerated,"28,56","15,03"
"low bq, many samples",UPN2_064,17,7577051,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His296Pro/c.887A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),10103,236,10425,"0,0226378897",0,0,0,0,1,0,0,0,1,NO,NO,COSM43858,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,279,Tolerated,"28,7","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_065,17,7577051,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His296Pro/c.887A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),9733,210,9982,"0,0210378682",0,0,0,0,1,0,0,0,1,NO,NO,COSM43858,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,279,Tolerated,"28,73","14,63"
"low bq, many samples",UPN2_066,17,7577051,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His296Pro/c.887A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),16587,383,17064,"0,0224449133",0,0,0,0,1,0,0,0,1,NO,NO,COSM43858,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,279,Tolerated,"28,57","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_067,17,7577051,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His296Pro/c.887A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),16502,369,16957,"0,0217609247",0,0,0,0,1,0,0,0,1,NO,NO,COSM43858,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,279,Tolerated,"28,74","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_068,17,7577051,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His296Pro/c.887A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),16922,381,17409,"0,0218852318",0,0,0,0,1,0,0,0,1,NO,NO,COSM43858,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,279,Tolerated,"28,62","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_069,17,7577051,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His296Pro/c.887A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),18724,406,19236,"0,0211062591",0,0,0,0,1,0,0,0,1,NO,NO,COSM43858,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,279,Tolerated,"28,6","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_070,17,7577051,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His296Pro/c.887A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),12418,242,12754,"0,0189744394",0,0,0,0,1,0,0,0,1,NO,NO,COSM43858,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,279,Tolerated,"28,57","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_071,17,7577051,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His296Pro/c.887A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),15408,343,15867,"0,0216171929",0,0,0,0,1,0,0,0,1,NO,NO,COSM43858,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,279,Tolerated,"28,57","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_072,17,7577051,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His296Pro/c.887A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),17463,362,17956,"0,0201603921",0,0,0,0,1,0,0,0,1,NO,NO,COSM43858,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,279,Tolerated,"28,54","14,86"
"low bq, many samples",UPN2_073,17,7577051,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His296Pro/c.887A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),9449,220,9724,"0,0226244344",0,0,0,0,1,0,0,0,1,NO,NO,COSM43858,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,279,Tolerated,"28,62","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_074,17,7577051,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His296Pro/c.887A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),11020,224,11297,"0,019828273",0,0,0,0,1,0,0,0,1,NO,NO,COSM43858,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,279,Tolerated,"28,41","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_075,17,7577051,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His296Pro/c.887A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),23954,503,24626,"0,0204255665",0,0,0,0,1,0,0,0,1,NO,NO,COSM43858,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,279,Tolerated,"28,6","14,97"
"low bq, many samples",UPN2_076,17,7577051,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His296Pro/c.887A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),14972,346,15385,"0,0224894378",0,0,0,0,1,0,0,0,1,NO,NO,COSM43858,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,279,Tolerated,"28,47","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_077,17,7577051,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His296Pro/c.887A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),16358,345,16803,"0,0205320478",0,0,0,0,1,0,0,0,1,NO,NO,COSM43858,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,279,Tolerated,"28,55","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_078,17,7577051,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His296Pro/c.887A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),18791,424,19328,"0,0219370861",0,0,0,0,1,0,0,0,1,NO,NO,COSM43858,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,279,Tolerated,"28,65","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_079,17,7577051,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His296Pro/c.887A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),11125,233,11426,"0,0203920882",0,0,0,0,1,0,0,0,1,NO,NO,COSM43858,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,279,Tolerated,"28,52","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_080,17,7577051,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His296Pro/c.887A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),15710,342,16138,"0,0211922171",0,0,0,0,1,0,0,0,1,NO,NO,COSM43858,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,279,Tolerated,"28,62","14,76"
"low bq, many samples",UPN2_081,17,7577051,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His296Pro/c.887A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),10169,233,10469,"0,0222561849",0,0,0,0,1,0,0,0,1,NO,NO,COSM43858,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,279,Tolerated,"28,82","15,52"
"low bq, low freq, many artifacts, many samples",UPN2_082,17,7577051,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His296Pro/c.887A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),15730,326,16143,"0,0201945116",0,0,0,0,1,0,0,0,1,NO,NO,COSM43858,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,279,Tolerated,"28,59",15
"low bq, many samples",UPN2_083,17,7577051,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His296Pro/c.887A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),20970,497,21574,"0,023036989",0,0,0,0,1,0,0,0,1,NO,NO,COSM43858,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,279,Tolerated,"28,52","14,84"
"low bq, many samples",UPN2_084,17,7577051,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His296Pro/c.887A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),21512,489,22137,"0,0220897141",0,0,0,0,1,0,0,0,1,NO,NO,COSM43858,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,279,Tolerated,"28,53","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_085,17,7577051,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His296Pro/c.887A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),12203,261,12536,"0,0208200383",0,0,0,0,1,0,0,0,1,NO,NO,COSM43858,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,279,Tolerated,"28,6","15,16"
"low bq, many samples",UPN2_086,17,7577051,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His296Pro/c.887A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),8888,203,9145,"0,0221979224",0,0,0,0,1,0,0,0,1,NO,NO,COSM43858,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,279,Tolerated,"28,47","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_087,17,7577051,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His296Pro/c.887A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),19707,405,20251,"0,0199990124",0,0,0,0,1,0,0,0,1,NO,NO,COSM43858,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,279,Tolerated,"28,62","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_088,17,7577051,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His296Pro/c.887A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),15932,351,16410,"0,0213893967",0,0,0,0,1,0,0,0,1,NO,NO,COSM43858,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,279,Tolerated,"28,45","14,87"
"low bq, low freq, many artifacts",UPN2_094,17,7577051,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His296Pro/c.887A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),12989,134,13177,"0,0101692343",0,0,0,0,1,0,0,0,1,NO,NO,COSM43858,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,279,Tolerated,"30,51","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_059,17,7577057,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu294Ala/c.881A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),2605,31,2646,"0,0117157974",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,02",Neutral,477,Tolerated,"29,76","16,42"
"low bq, low freq, many artifacts, many samples",UPN2_060,17,7577057,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu294Ala/c.881A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),8995,117,9148,"0,0127896808",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,02",Neutral,477,Tolerated,"29,72","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_061,17,7577057,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu294Ala/c.881A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),10114,113,10272,"0,0110007788",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,02",Neutral,477,Tolerated,"29,72","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_062,17,7577057,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu294Ala/c.881A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),11416,123,11590,"0,0106125971",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,02",Neutral,477,Tolerated,"29,81","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_063,17,7577057,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu294Ala/c.881A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),11076,118,11234,"0,0105038277",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,02",Neutral,477,Tolerated,"29,89","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_064,17,7577057,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu294Ala/c.881A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),5107,60,5191,"0,0115584666",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,02",Neutral,477,Tolerated,"29,74","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_065,17,7577057,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu294Ala/c.881A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),4882,61,4966,"0,012283528",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,02",Neutral,477,Tolerated,"30,12","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_066,17,7577057,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu294Ala/c.881A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),8370,93,8494,"0,0109489051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,02",Neutral,477,Tolerated,"29,88","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_067,17,7577057,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu294Ala/c.881A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),8295,93,8420,"0,0110451306",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,02",Neutral,477,Tolerated,"29,77","15,9"
"low bq, low freq, many artifacts, many samples",UPN2_068,17,7577057,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu294Ala/c.881A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),8536,96,8666,"0,0110777752",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,02",Neutral,477,Tolerated,"29,82","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_069,17,7577057,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu294Ala/c.881A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),9416,116,9570,"0,0121212121",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,02",Neutral,477,Tolerated,"29,83","15,34"
"low bq, low freq, many artifacts, many samples",UPN2_070,17,7577057,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu294Ala/c.881A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),6256,64,6350,"0,0100787402",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,02",Neutral,477,Tolerated,"29,95","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_072,17,7577057,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu294Ala/c.881A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),8807,98,8937,"0,0109656484",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,02",Neutral,477,Tolerated,"29,89","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_073,17,7577057,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu294Ala/c.881A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),4762,55,4838,"0,011368334",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,02",Neutral,477,Tolerated,"29,94","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_075,17,7577057,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu294Ala/c.881A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),12067,133,12261,"0,0108474023",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,02",Neutral,477,Tolerated,"29,91","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_077,17,7577057,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu294Ala/c.881A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),8232,103,8380,"0,0122911695",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,02",Neutral,477,Tolerated,"29,9","15,17"
"low bq, low freq, many artifacts, many samples",UPN2_078,17,7577057,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu294Ala/c.881A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),9476,109,9641,"0,0113058811",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,02",Neutral,477,Tolerated,"29,87","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_079,17,7577057,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu294Ala/c.881A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),5603,69,5689,"0,0121286694",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,02",Neutral,477,Tolerated,"29,81","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_080,17,7577057,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu294Ala/c.881A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),7900,83,8023,"0,0103452574",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,02",Neutral,477,Tolerated,"29,91","16,8"
"low bq, low freq, many artifacts, many samples",UPN2_082,17,7577057,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu294Ala/c.881A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),7895,88,8013,"0,010982154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,02",Neutral,477,Tolerated,"29,75","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_083,17,7577057,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu294Ala/c.881A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),10547,134,10727,"0,012491843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,02",Neutral,477,Tolerated,"29,89","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_084,17,7577057,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu294Ala/c.881A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),10854,123,11024,"0,0111574746",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,02",Neutral,477,Tolerated,"29,8","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_085,17,7577057,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu294Ala/c.881A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),6135,65,6236,"0,0104233483",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,02",Neutral,477,Tolerated,"29,96","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_086,17,7577057,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu294Ala/c.881A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),4475,51,4551,"0,0112063283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,02",Neutral,477,Tolerated,"30,01","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_087,17,7577057,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu294Ala/c.881A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),9938,105,10090,"0,0104063429",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,02",Neutral,477,Tolerated,"29,88","15,32"
"low bq, low freq, many artifacts",UPN2_088,17,7577057,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu294Ala/c.881A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),8029,84,8147,"0,0103105438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,02",Neutral,477,Tolerated,"29,92","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_059,17,7577060,C,G,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly293Ala/c.878G>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),2590,32,2647,"0,0120891575",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,324,Tolerated,"31,61","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_064,17,7577060,C,G,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly293Ala/c.878G>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),5097,61,5198,"0,0117352828",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,324,Tolerated,"31,63","14,11"
"low bq, low freq, many artifacts, many samples",UPN2_065,17,7577060,C,G,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly293Ala/c.878G>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),4891,61,4970,"0,0122736419",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,324,Tolerated,"31,4",14
"low bq, low freq, many artifacts",UPN2_080,17,7577060,C,G,missense_variant(MODERATE|MISSENSE|gGg/gCg|p.Gly293Ala/c.878G>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),7895,86,8028,"0,0107125062",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,324,Tolerated,"31,56","14,44"
"inspected, many artifacts",UPN2_044,17,7577060,C,T,missense_variant(MODERATE|MISSENSE|gGg/gAg|p.Gly293Glu/c.878G>A|393|TP53|protein_coding|CODING|ENST00000269305|8|T),3062,34,3118,"0,0109044259",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,79",Neutral,"0,631",Tolerated,"31,97","31,12"
"Not in 2nd illumina, inspected, many artifacts",UPN2_006,17,7577063,T,C,missense_variant(MODERATE|MISSENSE|aAa/aGa|p.Lys292Arg/c.875A>G|393|TP53|protein_coding|CODING|ENST00000269305|8|C),3262,38,3306,"0,0114942529",0,0,0,0,1,0,0,1,2,NO,NO,COSM43624,"cervix, large_intestine, oesophagus, stomach, thyroid","1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-0,61",Neutral,"0,171",Tolerated,"34,21","34,61"
inspected,UPN2_044,17,7577070,G,A,missense_variant(MODERATE|MISSENSE|Cgc/Tgc|p.Arg290Cys/c.868C>T|393|TP53|protein_coding|CODING|ENST00000269305|8|A),3038,70,3120,"0,0224358974",0,0,0,0,1,0,0,1,2,NO,NO,"COSM45679, COSM3522691, COSM3522692, COSM1167879","haematopoietic_and_lymphoid_tissue, skin, thyroid, upper_aerodigestive_tract","1, 11, 1, 1",NO,NO,NO,"2,47E-005",NO,NO,"-4,56",Deleterious,"0,001",Damaging,"33,61","33,96"
"inspected, many artifacts",UPN2_056,17,7577072,A,T,missense_variant(MODERATE|MISSENSE|cTc/cAc|p.Leu289His/c.866T>A|393|TP53|protein_coding|CODING|ENST00000269305|8|T),992,21,1019,"0,0206084396",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,63",Neutral,"0,04",Damaging,"33,78","27,24"
"low bq, low freq, many artifacts, many samples",UPN2_042,17,7577074,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn288Lys/c.864T>A|393|TP53|protein_coding|CODING|ENST00000269305|8|T),7250,74,7344,"0,0100762527",0,0,0,0,1,0,0,0,1,NO,NO,COSM43736,stomach,1,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,1,Damaging,"33,84","17,27"
"low bq, low freq, many artifacts, many samples",UPN2_050,17,7577074,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn288Lys/c.864T>A|393|TP53|protein_coding|CODING|ENST00000269305|8|T),12326,125,12493,"0,0100056031",0,0,0,0,1,0,0,0,1,NO,NO,COSM43736,stomach,1,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,1,Damaging,"33,86","16,7"
"low bq, low freq, many artifacts, many samples",UPN2_051,17,7577074,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn288Lys/c.864T>A|393|TP53|protein_coding|CODING|ENST00000269305|8|T),8889,91,9007,"0,010103253",0,0,0,0,1,0,0,0,1,NO,NO,COSM43736,stomach,1,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,1,Damaging,"33,98","16,51"
"low bq, low freq, many artifacts, many samples",UPN2_059,17,7577096,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp281Ala/c.842A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),2609,31,2655,"0,0116760829",0,0,0,0,1,0,0,0,1,NO,NO,COSM1559473. COSM4781979. COSM11665. COSM4781978,central_nervous_system. upper_aerodigestive_tract,"4,1",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"28,61","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_060,17,7577096,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp281Ala/c.842A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),8998,143,9175,"0,0155858311",0,0,0,0,1,0,0,0,1,NO,NO,COSM1559473. COSM4781979. COSM11665. COSM4781978,central_nervous_system. upper_aerodigestive_tract,"4,1",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"28,59","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_061,17,7577096,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp281Ala/c.842A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),10090,168,10303,"0,0163059303",0,0,0,0,1,0,0,0,1,NO,NO,COSM1559473. COSM4781979. COSM11665. COSM4781978,central_nervous_system. upper_aerodigestive_tract,"4,1",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"28,67","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_062,17,7577096,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp281Ala/c.842A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),11415,161,11630,"0,0138435082",0,0,0,0,1,0,0,0,1,NO,NO,COSM1559473. COSM4781979. COSM11665. COSM4781978,central_nervous_system. upper_aerodigestive_tract,"4,1",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"28,58","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_063,17,7577096,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp281Ala/c.842A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),11058,161,11263,"0,0142945929",0,0,0,0,1,0,0,0,1,NO,NO,COSM1559473. COSM4781979. COSM11665. COSM4781978,central_nervous_system. upper_aerodigestive_tract,"4,1",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"28,67","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_064,17,7577096,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp281Ala/c.842A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),5106,76,5207,"0,0145957365",0,0,0,0,1,0,0,0,1,NO,NO,COSM1559473. COSM4781979. COSM11665. COSM4781978,central_nervous_system. upper_aerodigestive_tract,"4,1",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"28,81","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_065,17,7577096,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp281Ala/c.842A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),4887,70,4982,"0,0140505821",0,0,0,0,1,0,0,0,1,NO,NO,COSM1559473. COSM4781979. COSM11665. COSM4781978,central_nervous_system. upper_aerodigestive_tract,"4,1",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"28,67","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_066,17,7577096,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp281Ala/c.842A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),8318,154,8508,"0,0181006112",0,0,0,0,1,0,0,0,1,NO,NO,COSM1559473. COSM4781979. COSM11665. COSM4781978,central_nervous_system. upper_aerodigestive_tract,"4,1",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"28,62","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_067,17,7577096,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp281Ala/c.842A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),8301,119,8448,"0,0140861742",0,0,0,0,1,0,0,0,1,NO,NO,COSM1559473. COSM4781979. COSM11665. COSM4781978,central_nervous_system. upper_aerodigestive_tract,"4,1",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"28,72","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_068,17,7577096,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp281Ala/c.842A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),8500,136,8688,"0,0156537753",0,0,0,0,1,0,0,0,1,NO,NO,COSM1559473. COSM4781979. COSM11665. COSM4781978,central_nervous_system. upper_aerodigestive_tract,"4,1",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"28,74","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_069,17,7577096,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp281Ala/c.842A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),9395,160,9600,"0,0166666667",0,0,0,0,1,0,0,0,1,NO,NO,COSM1559473. COSM4781979. COSM11665. COSM4781978,central_nervous_system. upper_aerodigestive_tract,"4,1",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"28,88","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_070,17,7577096,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp281Ala/c.842A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),6254,93,6368,"0,0146042714",0,0,0,0,1,0,0,0,1,NO,NO,COSM1559473. COSM4781979. COSM11665. COSM4781978,central_nervous_system. upper_aerodigestive_tract,"4,1",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"28,72","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_071,17,7577096,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp281Ala/c.842A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),7765,113,7922,"0,0142640747",0,0,0,0,1,0,0,0,1,NO,NO,COSM1559473. COSM4781979. COSM11665. COSM4781978,central_nervous_system. upper_aerodigestive_tract,"4,1",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"28,69","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_072,17,7577096,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp281Ala/c.842A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),8785,136,8964,"0,0151717983",0,0,0,0,1,0,0,0,1,NO,NO,COSM1559473. COSM4781979. COSM11665. COSM4781978,central_nervous_system. upper_aerodigestive_tract,"4,1",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"28,58","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_073,17,7577096,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp281Ala/c.842A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),4741,83,4847,"0,0171239942",0,0,0,0,1,0,0,0,1,NO,NO,COSM1559473. COSM4781979. COSM11665. COSM4781978,central_nervous_system. upper_aerodigestive_tract,"4,1",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"28,88","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_074,17,7577096,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp281Ala/c.842A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),5533,97,5652,"0,0171620665",0,0,0,0,1,0,0,0,1,NO,NO,COSM1559473. COSM4781979. COSM11665. COSM4781978,central_nervous_system. upper_aerodigestive_tract,"4,1",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"28,66","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_075,17,7577096,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp281Ala/c.842A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),12046,185,12293,"0,015049215",0,0,0,0,1,0,0,0,1,NO,NO,COSM1559473. COSM4781979. COSM11665. COSM4781978,central_nervous_system. upper_aerodigestive_tract,"4,1",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"28,69","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_076,17,7577096,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp281Ala/c.842A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),7496,135,7675,"0,0175895765",0,0,0,0,1,0,0,0,1,NO,NO,COSM1559473. COSM4781979. COSM11665. COSM4781978,central_nervous_system. upper_aerodigestive_tract,"4,1",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"28,55","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_077,17,7577096,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp281Ala/c.842A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),8249,131,8407,"0,0155822529",0,0,0,0,1,0,0,0,1,NO,NO,COSM1559473. COSM4781979. COSM11665. COSM4781978,central_nervous_system. upper_aerodigestive_tract,"4,1",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"28,64","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_078,17,7577096,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp281Ala/c.842A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),9458,151,9665,"0,0156233833",0,0,0,0,1,0,0,0,1,NO,NO,COSM1559473. COSM4781979. COSM11665. COSM4781978,central_nervous_system. upper_aerodigestive_tract,"4,1",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"28,53","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_079,17,7577096,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp281Ala/c.842A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),5609,77,5708,"0,0134898388",0,0,0,0,1,0,0,0,1,NO,NO,COSM1559473. COSM4781979. COSM11665. COSM4781978,central_nervous_system. upper_aerodigestive_tract,"4,1",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"28,69","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_080,17,7577096,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp281Ala/c.842A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),7886,128,8046,"0,015908526",0,0,0,0,1,0,0,0,1,NO,NO,COSM1559473. COSM4781979. COSM11665. COSM4781978,central_nervous_system. upper_aerodigestive_tract,"4,1",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"28,45","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_081,17,7577096,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp281Ala/c.842A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),5123,70,5219,"0,0134125311",0,0,0,0,1,0,0,0,1,NO,NO,COSM1559473. COSM4781979. COSM11665. COSM4781978,central_nervous_system. upper_aerodigestive_tract,"4,1",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"28,84","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_082,17,7577096,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp281Ala/c.842A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),7890,111,8039,"0,0138076875",0,0,0,0,1,0,0,0,1,NO,NO,COSM1559473. COSM4781979. COSM11665. COSM4781978,central_nervous_system. upper_aerodigestive_tract,"4,1",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"28,59","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_083,17,7577096,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp281Ala/c.842A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),10507,179,10753,"0,0166465173",0,0,0,0,1,0,0,0,1,NO,NO,COSM1559473. COSM4781979. COSM11665. COSM4781978,central_nervous_system. upper_aerodigestive_tract,"4,1",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"28,68","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_084,17,7577096,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp281Ala/c.842A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),10819,188,11053,"0,0170089568",0,0,0,0,1,0,0,0,1,NO,NO,COSM1559473. COSM4781979. COSM11665. COSM4781978,central_nervous_system. upper_aerodigestive_tract,"4,1",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"28,86","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_085,17,7577096,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp281Ala/c.842A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),6127,104,6253,"0,0166320166",0,0,0,0,1,0,0,0,1,NO,NO,COSM1559473. COSM4781979. COSM11665. COSM4781978,central_nervous_system. upper_aerodigestive_tract,"4,1",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"28,99","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_086,17,7577096,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp281Ala/c.842A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),4470,81,4568,"0,017732049",0,0,0,0,1,0,0,0,1,NO,NO,COSM1559473. COSM4781979. COSM11665. COSM4781978,central_nervous_system. upper_aerodigestive_tract,"4,1",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"28,82","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_087,17,7577096,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp281Ala/c.842A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),9902,174,10115,"0,017202175",0,0,0,0,1,0,0,0,1,NO,NO,COSM1559473. COSM4781979. COSM11665. COSM4781978,central_nervous_system. upper_aerodigestive_tract,"4,1",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"28,69","14,71"
"low bq, low freq, many artifacts",UPN2_088,17,7577096,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp281Ala/c.842A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),8009,130,8168,"0,0159157689",0,0,0,0,1,0,0,0,1,NO,NO,COSM1559473. COSM4781979. COSM11665. COSM4781978,central_nervous_system. upper_aerodigestive_tract,"4,1",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"28,78","15,06"
"inspected, many artifacts",UPN2_043,17,7577098,T,G,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg280Ser/c.840A>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),7736,399,8188,"0,0487298486",0,0,0,0,1,0,0,1,2,NO,NO,"COSM1582360, COSM44233","stomach, lung, oesophagus, upper_aerodigestive_tract","2, 2, 1, 1",NO,NO,NO,NO,NO,NO,"-5,74",Deleterious,0,Damaging,"32,66","34,12"
inspected,UPN2_103,17,7577108,C,T,missense_variant(MODERATE|MISSENSE|tGt/tAt|p.Cys277Tyr/c.830G>A|393|TP53|protein_coding|CODING|ENST00000269305|8|T),5931,205,6154,"0,0333116672",0,0,0,0,1,0,0,1,2,NO,NO,COSM43737,"bone, breast, haematopoietic_and_lymphoid_tissue, large_intestine, liver, oesophagus, peritoneum, skin, stomach, urinary_tract","2, 1, 2, 1, 1, 2, 1, 1, 2, 2",NO,NO,NO,NA,NO,NO,"-10,53",Deleterious,0,Damaging,"34,3","35,4"
"Not in 2nd illumina, inspected, many artifacts",UPN2_006,17,7577120,C,G,missense_variant(MODERATE|MISSENSE|cGt/cCt|p.Arg273Pro/c.818G>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),3295,61,3366,"0,0181224005",0,0,0,0,1,1,0,0,2,NO,NO,"COSM1646808, COSM43896, COSM3726798, COSM165077","breast, lung, central_nervous_system, cervix, haematopoietic_and_lymphoid_tissue, large_intestine, liver, oesophagus, ovary, soft_tissue, stomach, upper_aerodigestive_tract","10, 28, 2, 1, 3, 1, 1, 2, 2, 1, 1, 5",NO,NO,NO,NO,NO,NO,"-6,7",Deleterious,0,Damaging,"34,81","31,46"
"inspected, many artifacts",UPN2_056,17,7577120,C,G,missense_variant(MODERATE|MISSENSE|cGt/cCt|p.Arg273Pro/c.818G>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),1011,40,1055,"0,0379146919",0,0,0,0,1,0,0,0,1,NO,NO,COSM1646808. COSM43896. COSM3726798. COSM165077,breast. lung. central_nervous_system. cervix. haematopoietic_and_lymphoid_tissue. large_intestine. liver. oesophagus. ovary. soft_tissue. stomach. upper_aerodigestive_tract,10. 28. 2. 1. 3. 1. 1. 2. 2. 1. 1. 5,NO,NO,NO,NO,NO,NO,"-6,7",Deleterious,0,Damaging,"34,22","30,2"
"inspected, many artifacts, low freq",UPN2_081,17,7577120,C,G,missense_variant(MODERATE|MISSENSE|cGt/cCt|p.Arg273Pro/c.818G>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),5214,64,5301,"0,0120731937",0,0,0,0,1,0,0,1,2,NO,NO,"COSM1646808, COSM43896, COSM3726798, COSM165077","breast, lung, central_nervous_system, cervix, haematopoietic_and_lymphoid_tissue, large_intestine, liver, oesophagus, ovary, soft_tissue, stomach, upper_aerodigestive_tract","10, 28, 2, 1, 3, 1, 1, 2, 2, 1, 1, 5",NO,NO,NO,NO,NO,NO,"-6,7",Deleterious,0,Damaging,"34,01","29,05"
"inspected, many artifacts",UPN2_041,17,7577140,TC,T,frameshift_variant(HIGH||gga/|p.Gly266fs/c.797delG|393|TP53|protein_coding|CODING|ENST00000269305|8|T),2794,89,2932,"0,0303547067",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,48",NA
"low freq, many artifacts",UPN2_041,17,7577141,C,G,missense_variant(MODERATE|MISSENSE|gGa/gCa|p.Gly266Ala/c.797G>C|393|TP53|protein_coding|CODING|ENST00000269305|8|G),2794,43,2932,"0,0146657572",0,0,0,0,0,0,0,1,1,NO,NO,COSM5047609. COSM5047608. COSM5047610. COSM45488,oesophagus. large_intestine. ovary,4. 1. 1,NO,NO,NO,NO,NO,NO,"-5,67",Deleterious,0,Damaging,"35,48","35,09"
"inspected, many artifacts",UPN2_041,17,7577144,AG,A,frameshift_variant(HIGH||ctg/|p.Leu265fs/c.793delC|393|TP53|protein_coding|CODING|ENST00000269305|8|A),2894,31,2932,"0,0105729877",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,92",NA
"inspected, many artifacts",UPN2_044,17,7577511,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu257Gln/c.770T>A|393|TP53|protein_coding|CODING|ENST00000269305|7|T),6420,67,6509,"0,0102934399",0,0,0,0,1,0,0,1,2,NO,NO,"COSM1230108, COSM1230109, COSM4139865, COSM43530, COSM4139864","central_nervous_system, large_intestine, ovary, breast, kidney, liver, oesophagus","5, 7, 6, 1, 1, 2, 2",NO,rs28934577,YES,NO,NO,NO,"-5,64",Deleterious,0,Damaging,"35,52","35,28"
"low bq, low freq, many artifacts, many samples",UPN2_059,17,7577542,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn247His/c.739A>C|393|TP53|protein_coding|CODING|ENST00000269305|7|G),32282,344,32785,"0,0104926033",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,9",Deleterious,0,Damaging,"30,16","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_060,17,7577542,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn247His/c.739A>C|393|TP53|protein_coding|CODING|ENST00000269305|7|G),37856,411,38454,"0,0106880949",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,9",Deleterious,0,Damaging,"30,06","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_061,17,7577542,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn247His/c.739A>C|393|TP53|protein_coding|CODING|ENST00000269305|7|G),44525,478,45221,"0,0105703103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,9",Deleterious,0,Damaging,"29,93","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_062,17,7577542,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn247His/c.739A>C|393|TP53|protein_coding|CODING|ENST00000269305|7|G),45339,475,45972,"0,0103323762",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,9",Deleterious,0,Damaging,"29,94","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_066,17,7577542,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn247His/c.739A>C|393|TP53|protein_coding|CODING|ENST00000269305|7|G),32447,337,32912,"0,0102394263",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,9",Deleterious,0,Damaging,"30,07","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_070,17,7577542,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn247His/c.739A>C|393|TP53|protein_coding|CODING|ENST00000269305|7|G),29893,304,30355,"0,0100148246",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,9",Deleterious,0,Damaging,"29,96","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_074,17,7577542,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn247His/c.739A>C|393|TP53|protein_coding|CODING|ENST00000269305|7|G),23566,246,23932,"0,0102791242",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,9",Deleterious,0,Damaging,"29,99","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_078,17,7577542,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn247His/c.739A>C|393|TP53|protein_coding|CODING|ENST00000269305|7|G),35547,388,36091,"0,0107506026",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,9",Deleterious,0,Damaging,"29,89","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_081,17,7577542,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn247His/c.739A>C|393|TP53|protein_coding|CODING|ENST00000269305|7|G),52717,539,53476,"0,0100792879",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,9",Deleterious,0,Damaging,"30,08","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_082,17,7577542,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn247His/c.739A>C|393|TP53|protein_coding|CODING|ENST00000269305|7|G),38387,408,38987,"0,0104650268",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,9",Deleterious,0,Damaging,"30,02","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_083,17,7577542,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn247His/c.739A>C|393|TP53|protein_coding|CODING|ENST00000269305|7|G),41379,421,41976,"0,0100295407",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,9",Deleterious,0,Damaging,"30,02","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_085,17,7577542,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn247His/c.739A>C|393|TP53|protein_coding|CODING|ENST00000269305|7|G),25968,278,26387,"0,010535491",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,9",Deleterious,0,Damaging,"29,97","14,43"
"low bq, low freq, many artifacts",UPN2_087,17,7577542,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn247His/c.739A>C|393|TP53|protein_coding|CODING|ENST00000269305|7|G),42377,435,43028,"0,010109696",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,9",Deleterious,0,Damaging,"30,13","14,44"
"inspected, many artifacts",UPN2_044,17,7577548,C,T,missense_variant(MODERATE|MISSENSE|Ggc/Agc|p.Gly245Ser/c.733G>A|393|TP53|protein_coding|CODING|ENST00000269305|7|T),12635,167,12863,"0,0129829744",0,0,0,0,1,1,0,1,3,"0,0116",NO,"COSM3356965, COSM6932, COSM121035, COSM121036, COSM1640833","breast, central_nervous_system, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, endometrium, kidney, liver, ovary, salivary_gland, skin, small_intestine, soft_tissue, urinary_tract, vulva","43, 65, 39, 199, 28, 42, 56, 12, 78, 28, 1, 3, 1, 4, 26, 1, 6, 4, 1, 20, 5",NO,rs28934575,YES,"8,24E-006",NO,NO,"-5,88",Deleterious,"0,003",Damaging,"33,11","33,38"
"inspected, many artifacts",UPN2_084,17,7577556,C,T,missense_variant(MODERATE|MISSENSE|tGc/tAc|p.Cys242Tyr/c.725G>A|393|TP53|protein_coding|CODING|ENST00000269305|7|T),40833,457,41455,"0,0110240019",0,0,0,0,1,1,0,1,3,NO,NO,"COSM2744612, COSM251397, COSM251396, COSM3403262, COSM10646","central_nervous_system, stomach, liver, lung, bone, breast, haematopoietic_and_lymphoid_tissue, large_intestine, ovary, prostate, salivary_gland, soft_tissue, upper_aerodigestive_tract, urinary_tract","10, 5, 6, 8, 1, 5, 2, 5, 4, 1, 1, 1, 3, 3",NO,rs121912655,YES,NO,NO,NO,"-10,74",Deleterious,0,Damaging,"32,92","33,32"
"inspected, many artifacts",UPN2_084,17,7577559,G,A,missense_variant(MODERATE|MISSENSE|tCc/tTc|p.Ser241Phe/c.722C>T|393|TP53|protein_coding|CODING|ENST00000269305|7|A),40579,642,41460,"0,0154848046",0,0,0,0,1,1,0,1,3,NO,NO,"COSM3522695, COSM214170, COSM10812, COSM214171, COSM1649402","breast, central_nervous_system, endometrium, lung, oesophagus, ovary, pancreas, skin, stomach, urinary_tract, large_intestine, biliary_tract, haematopoietic_and_lymphoid_tissue, liver, upper_aerodigestive_tract, vulva","18, 20, 10, 12, 13, 24, 17, 41, 6, 19, 17, 2, 4, 2, 2, 1",NO,rs28934573,YES,NO,NO,NO,"-5,86",Deleterious,0,Damaging,"32,93","31,86"
"low bq, low freq, many artifacts, many samples",UPN2_004,17,7577561,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser240Arg/c.720T>A|393|TP53|protein_coding|CODING|ENST00000269305|7|T),3258,39,3313,"0,011771808",0,0,0,0,1,0,0,0,1,NO,NO,COSM45261,haematopoietic_and_lymphoid_tissue. stomach. urinary_tract,2. 1. 1,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"32,73","21,03"
"low bq, low freq, many artifacts, many samples",UPN2_052,17,7577561,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser240Arg/c.720T>A|393|TP53|protein_coding|CODING|ENST00000269305|7|T),24980,255,25323,"0,0100698969",0,0,0,0,1,0,0,0,1,NO,NO,COSM45261,haematopoietic_and_lymphoid_tissue. stomach. urinary_tract,2. 1. 1,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"31,93","18,16"
"low bq, low freq, many artifacts, many samples",UPN2_058,17,7577561,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser240Arg/c.720T>A|393|TP53|protein_coding|CODING|ENST00000269305|7|T),47524,498,48285,"0,010313762",0,0,0,0,1,0,0,0,1,NO,NO,COSM45261,haematopoietic_and_lymphoid_tissue. stomach. urinary_tract,2. 1. 1,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"31,97","17,5"
"low bq, low freq, many artifacts, many samples",UPN2_041,17,7577569,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys238Ser/c.712T>A|393|TP53|protein_coding|CODING|ENST00000269305|7|T),77713,886,79168,"0,0111913905",0,0,0,0,1,0,0,0,1,NO,NO,COSM43700. COSM4340287. COSM4340289. COSM4340288. COSM4340290,bone. breast. haematopoietic_and_lymphoid_tissue. liver. lung. ovary. pancreas. skin. soft_tissue,1. 1. 6. 1. 2. 2. 1. 2. 1,NO,NO,NO,NO,NO,NO,"-9,76",Deleterious,0,Damaging,"32,27","20,99"
"low bq, low freq, many artifacts, many samples",UPN2_043,17,7577569,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys238Ser/c.712T>A|393|TP53|protein_coding|CODING|ENST00000269305|7|T),32310,335,32834,"0,0102028385",0,0,0,0,1,0,0,0,1,NO,NO,COSM43700. COSM4340287. COSM4340289. COSM4340288. COSM4340290,bone. breast. haematopoietic_and_lymphoid_tissue. liver. lung. ovary. pancreas. skin. soft_tissue,1. 1. 6. 1. 2. 2. 1. 2. 1,NO,NO,NO,NO,NO,NO,"-9,76",Deleterious,0,Damaging,"32,31","21,53"
"low bq, low freq, many artifacts, many samples",UPN2_045,17,7577569,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys238Ser/c.712T>A|393|TP53|protein_coding|CODING|ENST00000269305|7|T),48806,530,49718,"0,0106601231",0,0,0,0,1,0,0,0,1,NO,NO,COSM43700. COSM4340287. COSM4340289. COSM4340288. COSM4340290,bone. breast. haematopoietic_and_lymphoid_tissue. liver. lung. ovary. pancreas. skin. soft_tissue,1. 1. 6. 1. 2. 2. 1. 2. 1,NO,NO,NO,NO,NO,NO,"-9,76",Deleterious,0,Damaging,"32,23","20,46"
"low bq, low freq, many artifacts, many samples",UPN2_048,17,7577569,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys238Ser/c.712T>A|393|TP53|protein_coding|CODING|ENST00000269305|7|T),63143,654,64262,"0,0101770875",0,0,0,0,1,0,0,0,1,NO,NO,COSM43700. COSM4340287. COSM4340289. COSM4340288. COSM4340290,bone. breast. haematopoietic_and_lymphoid_tissue. liver. lung. ovary. pancreas. skin. soft_tissue,1. 1. 6. 1. 2. 2. 1. 2. 1,NO,NO,NO,NO,NO,NO,"-9,76",Deleterious,0,Damaging,"32,28","21,78"
"low bq, low freq, many artifacts, many samples",UPN2_050,17,7577569,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys238Ser/c.712T>A|393|TP53|protein_coding|CODING|ENST00000269305|7|T),47742,522,48618,"0,0107367642",0,0,0,0,1,0,0,0,1,NO,NO,COSM43700. COSM4340287. COSM4340289. COSM4340288. COSM4340290,bone. breast. haematopoietic_and_lymphoid_tissue. liver. lung. ovary. pancreas. skin. soft_tissue,1. 1. 6. 1. 2. 2. 1. 2. 1,NO,NO,NO,NO,NO,NO,"-9,76",Deleterious,0,Damaging,"32,28","20,36"
"low bq, low freq, many artifacts, many samples",UPN2_055,17,7577569,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys238Ser/c.712T>A|393|TP53|protein_coding|CODING|ENST00000269305|7|T),49823,514,50679,"0,010142268",0,0,0,0,1,0,0,0,1,NO,NO,COSM43700. COSM4340287. COSM4340289. COSM4340288. COSM4340290,bone. breast. haematopoietic_and_lymphoid_tissue. liver. lung. ovary. pancreas. skin. soft_tissue,1. 1. 6. 1. 2. 2. 1. 2. 1,NO,NO,NO,NO,NO,NO,"-9,76",Deleterious,0,Damaging,"32,27","20,47"
"low bq, low freq, many artifacts",UPN2_058,17,7577569,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys238Ser/c.712T>A|393|TP53|protein_coding|CODING|ENST00000269305|7|T),47489,543,48299,"0,0112424688",0,0,0,0,1,0,0,0,1,NO,NO,COSM43700. COSM4340287. COSM4340289. COSM4340288. COSM4340290,bone. breast. haematopoietic_and_lymphoid_tissue. liver. lung. ovary. pancreas. skin. soft_tissue,1. 1. 6. 1. 2. 2. 1. 2. 1,NO,NO,NO,NO,NO,NO,"-9,76",Deleterious,0,Damaging,"32,3","21,16"
"low bq, low freq, many artifacts, many samples",UPN2_041,17,7577571,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met237Lys/c.710T>A|393|TP53|protein_coding|CODING|ENST00000269305|7|T),77927,830,79184,"0,0104819155",0,0,0,0,1,0,0,0,1,NO,NO,COSM2744633. COSM984922. COSM4271816. COSM984920. COSM43952,endometrium. liver. stomach. breast. large_intestine. lung. ovary. upper_aerodigestive_tract,5. 10. 5. 2. 3. 1. 1. 1,NO,NO,NO,"8,24E-006",NO,NO,"-5,85",Deleterious,0,Damaging,"33,74","21,39"
"low bq, low freq, many artifacts, many samples",UPN2_044,17,7577571,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met237Lys/c.710T>A|393|TP53|protein_coding|CODING|ENST00000269305|7|T),12661,132,12876,"0,0102516309",0,0,0,0,1,0,0,0,1,NO,NO,COSM2744633. COSM984922. COSM4271816. COSM984920. COSM43952,endometrium. liver. stomach. breast. large_intestine. lung. ovary. upper_aerodigestive_tract,5. 10. 5. 2. 3. 1. 1. 1,NO,NO,NO,"8,24E-006",NO,NO,"-5,85",Deleterious,0,Damaging,"33,62","21,75"
"low freq, many artifacts, many samples",UPN2_006,17,7577575,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr236Asn/c.706T>A|393|TP53|protein_coding|CODING|ENST00000269305|7|T),17676,180,17894,"0,0100592377",0,0,0,0,1,0,0,0,1,NO,NO,COSM1644276. COSM1157852. COSM1157851. COSM43826. COSM3388353,haematopoietic_and_lymphoid_tissue. pancreas. skin. breast. central_nervous_system. oesophagus. stomach. upper_aerodigestive_tract,7. 13. 7. 1. 1. 2. 1. 4,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"34,03","27,12"
"low bq, low freq, many artifacts, many samples",UPN2_059,17,7577602,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser227Ala/c.679T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),32106,542,32842,"0,016503258",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,35,Damaging,"30,73","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_060,17,7577602,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser227Ala/c.679T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),37697,651,38508,"0,0169055781",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,35,Damaging,"30,8","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_061,17,7577602,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser227Ala/c.679T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),44179,791,45230,"0,0174883927",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,35,Damaging,"30,64","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_062,17,7577602,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser227Ala/c.679T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),45016,818,46033,"0,0177698608",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,35,Damaging,"30,61","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_063,17,7577602,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser227Ala/c.679T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),47035,857,48066,"0,0178296509",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,35,Damaging,"30,74","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_064,17,7577602,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser227Ala/c.679T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),54030,960,55262,"0,0173717926",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,35,Damaging,"30,62","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_065,17,7577602,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser227Ala/c.679T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),29144,505,29813,"0,0169389193",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,35,Damaging,"30,75","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_066,17,7577602,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser227Ala/c.679T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),32230,506,32922,"0,0153696616",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,35,Damaging,"30,79","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_067,17,7577602,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser227Ala/c.679T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),34269,552,34968,"0,0157858614",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,35,Damaging,"30,85","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_068,17,7577602,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser227Ala/c.679T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),34382,603,35128,"0,0171657937",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,35,Damaging,"30,55","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_069,17,7577602,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser227Ala/c.679T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),44636,757,45669,"0,0165757954",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,35,Damaging,"30,61","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_070,17,7577602,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser227Ala/c.679T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),29700,551,30395,"0,0181279816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,35,Damaging,"30,64","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_071,17,7577602,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser227Ala/c.679T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),32260,574,32998,"0,0173949936",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,35,Damaging,"30,78","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_072,17,7577602,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser227Ala/c.679T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),44104,760,45050,"0,0168701443",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,35,Damaging,"30,71","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_073,17,7577602,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser227Ala/c.679T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),30957,451,31529,"0,0143042913",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,35,Damaging,"30,67","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_074,17,7577602,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser227Ala/c.679T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),23481,380,23958,"0,0158610902",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,35,Damaging,"30,86","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_075,17,7577602,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser227Ala/c.679T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),47524,767,48498,"0,0158150852",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,35,Damaging,"30,8","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_076,17,7577602,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser227Ala/c.679T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),32532,634,33325,"0,0190247562",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,35,Damaging,"30,67","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_077,17,7577602,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser227Ala/c.679T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),34787,608,35556,"0,0170997863",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,35,Damaging,"30,59","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_078,17,7577602,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser227Ala/c.679T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),35346,617,36093,"0,0170947275",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,35,Damaging,"30,6","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_079,17,7577602,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser227Ala/c.679T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),24472,427,25014,"0,0170704406",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,35,Damaging,"30,75","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_080,17,7577602,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser227Ala/c.679T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),37661,692,38512,"0,0179684254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,35,Damaging,"30,74","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_081,17,7577602,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser227Ala/c.679T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),52457,873,53549,"0,0163028254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,35,Damaging,"30,7","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_082,17,7577602,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser227Ala/c.679T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),38221,637,39035,"0,0163186884",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,35,Damaging,"30,81","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_083,17,7577602,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser227Ala/c.679T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),41114,728,42006,"0,0173308575",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,35,Damaging,"30,66","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_084,17,7577602,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser227Ala/c.679T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),40513,748,41425,"0,018056729",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,35,Damaging,"30,62","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_085,17,7577602,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser227Ala/c.679T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),25813,446,26393,"0,01689842",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,35,Damaging,"30,64","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_086,17,7577602,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser227Ala/c.679T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),19485,399,20001,"0,0199490025",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,35,Damaging,"30,55","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_087,17,7577602,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser227Ala/c.679T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),42145,744,43085,"0,0172681908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,35,Damaging,"30,62","14,74"
"low bq, low freq, many artifacts",UPN2_088,17,7577602,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser227Ala/c.679T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),32050,519,32737,"0,0158536213",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,35,Damaging,"30,79","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_059,17,7577607,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val225Gly/c.674T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),31802,720,32776,"0,0219672931",0,0,0,0,1,0,0,0,1,NO,NO,COSM4770727,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,0,Damaging,"27,13","14,79"
"low bq, many samples",UPN2_060,17,7577607,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val225Gly/c.674T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),37225,857,38418,"0,0223072518",0,0,0,0,1,0,0,0,1,NO,NO,COSM4770727,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,0,Damaging,"27,18","14,58"
"low bq, bad alignment, many samples",UPN2_061,17,7577607,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val225Gly/c.674T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),43759,1006,45102,"0,0223049976",0,0,0,0,1,0,0,0,1,NO,NO,COSM4770727,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,0,Damaging,"26,93","14,92"
"low bq, bad alignment, many samples",UPN2_062,17,7577607,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val225Gly/c.674T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),44428,1128,45923,"0,0245628552",0,0,0,0,1,0,0,0,1,NO,NO,COSM4770727,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,0,Damaging,"26,97","14,47"
"low bq, many samples",UPN2_063,17,7577607,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val225Gly/c.674T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),46465,1133,47951,"0,0236282872",0,0,0,0,1,0,0,0,1,NO,NO,COSM4770727,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,0,Damaging,"27,09","14,67"
many samples,UPN2_064,17,7577607,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val225Gly/c.674T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),53391,1267,55083,"0,0230016521",0,0,0,0,1,0,0,0,1,NO,NO,COSM4770727,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,0,Damaging,27,"14,82"
"low bq, low freq, many artifacts, many samples",UPN2_065,17,7577607,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val225Gly/c.674T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),28832,648,29744,"0,0217859064",0,0,0,0,1,0,0,0,1,NO,NO,COSM4770727,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,0,Damaging,"27,07","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_066,17,7577607,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val225Gly/c.674T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),31944,638,32834,"0,0194310775",0,0,0,0,1,0,0,0,1,NO,NO,COSM4770727,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,0,Damaging,"27,1","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_067,17,7577607,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val225Gly/c.674T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),33889,740,34887,"0,0212113395",0,0,0,0,1,0,0,0,1,NO,NO,COSM4770727,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,0,Damaging,"27,26","14,67"
"low bq, bad alignment, many samples",UPN2_068,17,7577607,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val225Gly/c.674T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),33865,879,35033,"0,0250906288",0,0,0,0,1,0,0,0,1,NO,NO,COSM4770727,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,0,Damaging,"26,93","14,84"
"low bq, bad alignment, many samples",UPN2_069,17,7577607,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val225Gly/c.674T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),44137,1022,45549,"0,0224373751",0,0,0,0,1,0,0,0,1,NO,NO,COSM4770727,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,0,Damaging,"26,95","14,44"
"low bq, bad alignment, many samples",UPN2_070,17,7577607,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val225Gly/c.674T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),29399,680,30311,"0,0224340998",0,0,0,0,1,0,0,0,1,NO,NO,COSM4770727,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,0,Damaging,"26,95","14,62"
"low bq, many samples",UPN2_071,17,7577607,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val225Gly/c.674T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),31922,754,32921,"0,022903314",0,0,0,0,1,0,0,0,1,NO,NO,COSM4770727,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,0,Damaging,"27,06","14,56"
"low bq, many samples",UPN2_072,17,7577607,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val225Gly/c.674T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),43591,991,44936,"0,0220535873",0,0,0,0,1,0,0,0,1,NO,NO,COSM4770727,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,0,Damaging,"27,1","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_073,17,7577607,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val225Gly/c.674T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),30516,668,31452,"0,021238713",0,0,0,0,1,0,0,0,1,NO,NO,COSM4770727,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,0,Damaging,"27,18","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_074,17,7577607,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val225Gly/c.674T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),23274,447,23891,"0,0187099745",0,0,0,0,1,0,0,0,1,NO,NO,COSM4770727,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,0,Damaging,"27,04","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_075,17,7577607,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val225Gly/c.674T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),47053,1004,48411,"0,0207390882",0,0,0,0,1,0,0,0,1,NO,NO,COSM4770727,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,0,Damaging,"27,26","14,82"
many samples,UPN2_076,17,7577607,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val225Gly/c.674T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),32176,794,33223,"0,023899106",0,0,0,0,1,0,0,0,1,NO,NO,COSM4770727,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,0,Damaging,27,"14,6"
many samples,UPN2_077,17,7577607,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val225Gly/c.674T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),34384,803,35473,"0,0226369351",0,0,0,0,1,0,0,0,1,NO,NO,COSM4770727,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,0,Damaging,27,"14,49"
"low bq, bad alignment, many samples",UPN2_078,17,7577607,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val225Gly/c.674T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),34824,895,35998,"0,0248624924",0,0,0,0,1,0,0,0,1,NO,NO,COSM4770727,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,0,Damaging,"26,92","14,6"
"low bq, many samples",UPN2_079,17,7577607,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val225Gly/c.674T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),24133,578,24952,"0,0231644758",0,0,0,0,1,0,0,0,1,NO,NO,COSM4770727,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,0,Damaging,"27,15","14,46"
"low bq, many samples",UPN2_080,17,7577607,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val225Gly/c.674T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),37191,916,38421,"0,0238411285",0,0,0,0,1,0,0,0,1,NO,NO,COSM4770727,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,0,Damaging,"27,13","14,61"
"low bq, many samples",UPN2_081,17,7577607,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val225Gly/c.674T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),51635,1318,53409,"0,0246774888",0,0,0,0,1,0,0,0,1,NO,NO,COSM4770727,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,0,Damaging,"27,07","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_082,17,7577607,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val225Gly/c.674T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),37804,851,38933,"0,0218580639",0,0,0,0,1,0,0,0,1,NO,NO,COSM4770727,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,0,Damaging,"27,13","14,44"
"low bq, bad alignment, many samples",UPN2_083,17,7577607,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val225Gly/c.674T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),40642,934,41880,"0,0223018147",0,0,0,0,1,0,0,0,1,NO,NO,COSM4770727,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,0,Damaging,"26,97","14,57"
"low bq, bad alignment, many samples",UPN2_084,17,7577607,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val225Gly/c.674T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),39921,1040,41289,"0,0251883068",0,0,0,0,1,0,0,0,1,NO,NO,COSM4770727,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,0,Damaging,"26,93","14,45"
"low bq, bad alignment, many samples",UPN2_085,17,7577607,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val225Gly/c.674T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),25499,611,26306,"0,0232266403",0,0,0,0,1,0,0,0,1,NO,NO,COSM4770727,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,0,Damaging,"26,98","14,6"
"low bq, bad alignment, many samples",UPN2_086,17,7577607,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val225Gly/c.674T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),19314,480,19957,"0,0240517112",0,0,0,0,1,0,0,0,1,NO,NO,COSM4770727,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,0,Damaging,"26,89","14,4"
"low bq, many samples",UPN2_087,17,7577607,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val225Gly/c.674T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),41644,975,42965,"0,0226928896",0,0,0,0,1,0,0,0,1,NO,NO,COSM4770727,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,0,Damaging,"27,12","14,49"
"low bq, low freq, many artifacts",UPN2_088,17,7577607,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val225Gly/c.674T>G|393|TP53|protein_coding|CODING|ENST00000269305|7|C),31748,671,32661,"0,0205443801",0,0,0,0,1,0,0,0,1,NO,NO,COSM4770727,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,0,Damaging,"27,26","14,47"
"inspected, many artifacts",UPN2_092,17,7578191,A,G,missense_variant(MODERATE|MISSENSE|Tat/Cat|p.Tyr220His/c.658T>C|393|TP53|protein_coding|CODING|ENST00000269305|6|G),2402,27,2430,"0,0111111111",0,0,0,0,1,0,0,1,2,NO,0,"COSM1172476, COSM1172477, COSM3732687, COSM3732688, COSM44637","breast, central_nervous_system, oesophagus, haematopoietic_and_lymphoid_tissue, ovary, urinary_tract","12, 5, 11, 2, 1, 1",NO,NO,NO,"1,65E-005",NO,NO,"-4,78",Deleterious,"0,061",Tolerated,"35,8","35,04"
"low bq, low freq, many artifacts",UPN2_077,17,7578196,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val218Gly/c.653T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),4718,54,4796,"0,0112593828",0,0,0,0,1,0,0,0,1,NO,NO,COSM3890514. COSM3890513. COSM3890511. COSM44198. COSM3890512,skin. central_nervous_system. haematopoietic_and_lymphoid_tissue. lung. ovary. upper_aerodigestive_tract,10. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,55",Deleterious,0,Damaging,"28,04","14,46"
"inspected, many artifacts",UPN2_044,17,7578196,A,G,missense_variant(MODERATE|MISSENSE|gTg/gCg|p.Val218Ala/c.653T>C|393|TP53|protein_coding|CODING|ENST00000269305|6|G),2659,44,2713,"0,0162182086",0,0,0,0,1,0,0,1,2,NO,NO,COSM44930,"liver, lung, upper_aerodigestive_tract","1, 1, 1",NO,NO,NO,NO,NO,NO,"-3,69",Deleterious,0,Damaging,"28,92","35,14"
"low bq, low freq, many artifacts, many samples",UPN2_061,17,7578199,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val217Gly/c.650T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),6852,70,6946,"0,0100777426",0,0,0,0,1,0,0,0,1,NO,NO,COSM3787446. COSM3787445. COSM44375. COSM3787444. COSM3787447,oesophagus. pancreas,"8,6",NO,NO,NO,NO,NO,NO,"-4,31",Deleterious,0,Damaging,"29,12","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_062,17,7578199,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val217Gly/c.650T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),6165,82,6274,"0,0130698119",0,0,0,0,1,0,0,0,1,NO,NO,COSM3787446. COSM3787445. COSM44375. COSM3787444. COSM3787447,oesophagus. pancreas,"8,6",NO,NO,NO,NO,NO,NO,"-4,31",Deleterious,0,Damaging,"29,22","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_063,17,7578199,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val217Gly/c.650T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),7463,81,7560,"0,0107142857",0,0,0,0,1,0,0,0,1,NO,NO,COSM3787446. COSM3787445. COSM44375. COSM3787444. COSM3787447,oesophagus. pancreas,"8,6",NO,NO,NO,NO,NO,NO,"-4,31",Deleterious,0,Damaging,"29,2","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_064,17,7578199,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val217Gly/c.650T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),9573,107,9738,"0,0109878825",0,0,0,0,1,0,0,0,1,NO,NO,COSM3787446. COSM3787445. COSM44375. COSM3787444. COSM3787447,oesophagus. pancreas,"8,6",NO,NO,NO,NO,NO,NO,"-4,31",Deleterious,0,Damaging,"29,55","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_066,17,7578199,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val217Gly/c.650T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),5859,62,5955,"0,010411419",0,0,0,0,1,0,0,0,1,NO,NO,COSM3787446. COSM3787445. COSM44375. COSM3787444. COSM3787447,oesophagus. pancreas,"8,6",NO,NO,NO,NO,NO,NO,"-4,31",Deleterious,0,Damaging,"29,56","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_069,17,7578199,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val217Gly/c.650T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),6078,75,6185,"0,0121261116",0,0,0,0,1,0,0,0,1,NO,NO,COSM3787446. COSM3787445. COSM44375. COSM3787444. COSM3787447,oesophagus. pancreas,"8,6",NO,NO,NO,NO,NO,NO,"-4,31",Deleterious,0,Damaging,"28,97","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_070,17,7578199,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val217Gly/c.650T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),4157,50,4225,"0,0118343195",0,0,0,0,1,0,0,0,1,NO,NO,COSM3787446. COSM3787445. COSM44375. COSM3787444. COSM3787447,oesophagus. pancreas,"8,6",NO,NO,NO,NO,NO,NO,"-4,31",Deleterious,0,Damaging,"29,01","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_073,17,7578199,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val217Gly/c.650T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),4661,50,4724,"0,0105842506",0,0,0,0,1,0,0,0,1,NO,NO,COSM3787446. COSM3787445. COSM44375. COSM3787444. COSM3787447,oesophagus. pancreas,"8,6",NO,NO,NO,NO,NO,NO,"-4,31",Deleterious,0,Damaging,"29,51","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_076,17,7578199,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val217Gly/c.650T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),4818,51,4893,"0,0104230533",0,0,0,0,1,0,0,0,1,NO,NO,COSM3787446. COSM3787445. COSM44375. COSM3787444. COSM3787447,oesophagus. pancreas,"8,6",NO,NO,NO,NO,NO,NO,"-4,31",Deleterious,0,Damaging,"28,8","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_077,17,7578199,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val217Gly/c.650T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),4724,50,4801,"0,010414497",0,0,0,0,1,0,0,0,1,NO,NO,COSM3787446. COSM3787445. COSM44375. COSM3787444. COSM3787447,oesophagus. pancreas,"8,6",NO,NO,NO,NO,NO,NO,"-4,31",Deleterious,0,Damaging,"29,14","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_080,17,7578199,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val217Gly/c.650T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),5666,61,5758,"0,0105939562",0,0,0,0,1,0,0,0,1,NO,NO,COSM3787446. COSM3787445. COSM44375. COSM3787444. COSM3787447,oesophagus. pancreas,"8,6",NO,NO,NO,NO,NO,NO,"-4,31",Deleterious,0,Damaging,"29,39","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_081,17,7578199,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val217Gly/c.650T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),9239,102,9393,"0,0108591504",0,0,0,0,1,0,0,0,1,NO,NO,COSM3787446. COSM3787445. COSM44375. COSM3787444. COSM3787447,oesophagus. pancreas,"8,6",NO,NO,NO,NO,NO,NO,"-4,31",Deleterious,0,Damaging,"29,58","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_082,17,7578199,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val217Gly/c.650T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),6722,71,6823,"0,0104059798",0,0,0,0,1,0,0,0,1,NO,NO,COSM3787446. COSM3787445. COSM44375. COSM3787444. COSM3787447,oesophagus. pancreas,"8,6",NO,NO,NO,NO,NO,NO,"-4,31",Deleterious,0,Damaging,"29,69","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_083,17,7578199,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val217Gly/c.650T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),6740,77,6846,"0,0112474438",0,0,0,0,1,0,0,0,1,NO,NO,COSM3787446. COSM3787445. COSM44375. COSM3787444. COSM3787447,oesophagus. pancreas,"8,6",NO,NO,NO,NO,NO,NO,"-4,31",Deleterious,0,Damaging,"29,02","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_084,17,7578199,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val217Gly/c.650T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),6489,82,6599,"0,0124261252",0,0,0,0,1,0,0,0,1,NO,NO,COSM3787446. COSM3787445. COSM44375. COSM3787444. COSM3787447,oesophagus. pancreas,"8,6",NO,NO,NO,NO,NO,NO,"-4,31",Deleterious,0,Damaging,"28,77","17,39"
"low bq, low freq, many artifacts",UPN2_086,17,7578199,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val217Gly/c.650T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),3303,35,3351,"0,0104446434",0,0,0,0,1,0,0,0,1,NO,NO,COSM3787446. COSM3787445. COSM44375. COSM3787444. COSM3787447,oesophagus. pancreas,"8,6",NO,NO,NO,NO,NO,NO,"-4,31",Deleterious,0,Damaging,"28,64","14,83"
"Not in 2nd illumina, inspected, many artifacts",UPN2_006,17,7578215,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe212Leu/c.634T>C|393|TP53|protein_coding|CODING|ENST00000269305|6|G),3029,60,3092,"0,0194049159",0,0,0,0,1,0,0,1,2,NO,NO,COSM45477,upper_aerodigestive_tract,1,NO,NO,NO,NO,NO,NO,"-0,33",Neutral,"0,172",Tolerated,"35,39","35,8"
"inspected, many artifacts",UPN2_044,17,7578217,G,T,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr211Asn/c.632C>A|393|TP53|protein_coding|CODING|ENST00000269305|6|T),2673,39,2715,"0,0143646409",0,0,0,0,1,0,0,1,2,NO,NO,COSM44661,"bone, haematopoietic_and_lymphoid_tissue, upper_aerodigestive_tract, urinary_tract","1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-4,4",Deleterious,"0,011",Damaging,"35,09",34
"low freq, many artifacts",UPN2_090,17,7578238,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu204Val/c.611A>T|393|TP53|protein_coding|CODING|ENST00000269305|6|A),3074,32,3115,"0,0102728732",0,0,0,0,1,0,0,0,1,NO,NO,COSM44652,autonomic_ganglia,1,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,45,Damaging,"35,19","27,41"
"low bq, many samples",UPN2_059,17,7578241,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val203Gly/c.608T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),6482,169,6683,"0,0252880443",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,4,Damaging,"27,51","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_060,17,7578241,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val203Gly/c.608T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),6199,124,6343,"0,0195491093",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,4,Damaging,"27,61","14,73"
"low bq, many samples",UPN2_061,17,7578241,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val203Gly/c.608T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),6745,168,6943,"0,024197033",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,4,Damaging,"27,31","15,56"
"low bq, many samples",UPN2_062,17,7578241,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val203Gly/c.608T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),6078,163,6268,"0,0260051053",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,4,Damaging,"27,01","14,61"
"low bq, many samples",UPN2_063,17,7578241,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val203Gly/c.608T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),7354,167,7554,"0,0221074927",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,4,Damaging,"27,48","14,6"
"low bq, many samples",UPN2_064,17,7578241,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val203Gly/c.608T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),9455,237,9734,"0,0243476474",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,4,Damaging,"27,57","14,64"
"low bq, many samples",UPN2_065,17,7578241,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val203Gly/c.608T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),5852,138,6025,"0,0229045643",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,4,Damaging,"27,57","15,23"
"low bq, many samples",UPN2_066,17,7578241,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val203Gly/c.608T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),5785,143,5953,"0,0240215018",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,4,Damaging,"27,69","14,61"
"low bq, many samples",UPN2_067,17,7578241,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val203Gly/c.608T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),5643,147,5819,"0,0252620725",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,4,Damaging,"28,03","15,48"
"low bq, many samples",UPN2_068,17,7578241,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val203Gly/c.608T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),4972,137,5126,"0,0267264924",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,4,Damaging,"27,22","15,09"
"low bq, many samples",UPN2_069,17,7578241,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val203Gly/c.608T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),6001,160,6185,"0,025869038",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,4,Damaging,"27,52","15,18"
"low bq, many samples",UPN2_070,17,7578241,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val203Gly/c.608T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),4092,107,4223,"0,0253374378",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,4,Damaging,"27,01","14,91"
"low bq, many samples",UPN2_071,17,7578241,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val203Gly/c.608T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),4826,140,5003,"0,0279832101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,4,Damaging,"27,34","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_072,17,7578241,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val203Gly/c.608T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),6185,136,6357,"0,0213937392",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,4,Damaging,"27,47","15,38"
"low bq, many samples",UPN2_073,17,7578241,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val203Gly/c.608T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),4586,126,4726,"0,0266610241",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,4,Damaging,"27,78","14,86"
"low bq, many samples",UPN2_074,17,7578241,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val203Gly/c.608T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),3753,85,3854,"0,0220550078",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,4,Damaging,"27,68","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_075,17,7578241,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val203Gly/c.608T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),6774,149,6951,"0,0214357646",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,4,Damaging,"28,03","15,43"
"low bq, many samples",UPN2_076,17,7578241,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val203Gly/c.608T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),4731,133,4893,"0,0271816881",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,4,Damaging,"27,02","15,28"
"low bq, many samples",UPN2_077,17,7578241,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val203Gly/c.608T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),4667,120,4799,"0,0250052094",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,4,Damaging,"27,29","15,48"
"low bq, many samples",UPN2_078,17,7578241,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val203Gly/c.608T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),5854,145,6035,"0,024026512",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,4,Damaging,"27,19","14,46"
"low bq, many samples",UPN2_079,17,7578241,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val203Gly/c.608T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),3458,95,3573,"0,0265883011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,4,Damaging,"27,53","14,62"
"low bq, many samples",UPN2_080,17,7578241,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val203Gly/c.608T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),5593,143,5753,"0,0248565966",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,4,Damaging,"27,45","15,15"
"low bq, many samples",UPN2_081,17,7578241,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val203Gly/c.608T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),9124,210,9386,"0,0223737481",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,4,Damaging,"27,65","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_082,17,7578241,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val203Gly/c.608T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),6659,131,6821,"0,0192053951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,4,Damaging,"27,58","14,69"
"low bq, bad alignment, many samples",UPN2_083,17,7578241,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val203Gly/c.608T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),6621,181,6850,"0,0264233577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,4,Damaging,"26,79","14,73"
"low bq, many samples",UPN2_084,17,7578241,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val203Gly/c.608T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),6405,167,6597,"0,0253145369",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,4,Damaging,"27,22","15,06"
"low bq, many samples",UPN2_085,17,7578241,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val203Gly/c.608T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),4450,114,4593,"0,0248203788",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,4,Damaging,"27,08","15,32"
"low bq, many samples",UPN2_086,17,7578241,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val203Gly/c.608T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),3254,87,3349,"0,0259779039",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,4,Damaging,"27,09","14,97"
"low bq, many samples",UPN2_087,17,7578241,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val203Gly/c.608T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),7147,169,7357,"0,0229713198",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,4,Damaging,"27,26","14,74"
low bq,UPN2_088,17,7578241,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val203Gly/c.608T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),5053,116,5201,"0,0223034032",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,4,Damaging,"28,04","14,52"
"inspected, bad alignment, many artifacts",UPN2_084,17,7578242,C,T,missense_variant(MODERATE|MISSENSE|Gtg/Atg|p.Val203Met/c.607G>A|393|TP53|protein_coding|CODING|ENST00000269305|6|T),6192,411,6610,"0,0621785174",0,0,0,0,1,0,0,1,2,NO,NO,COSM43599,"large_intestine, urinary_tract","1, 1",NO,NO,NO,NO,NO,NO,"-0,81",Neutral,0,Damaging,"34,38","31,93"
"Not in 2nd illumina, inspected, many artifacts",UPN2_006,17,7578248,A,T,missense_variant(MODERATE|MISSENSE|Ttg/Atg|p.Leu201Met/c.601T>A|393|TP53|protein_coding|CODING|ENST00000269305|6|T),6013,86,6114,"0,0140660779",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,68",Neutral,"0,209",Tolerated,"33,17","29,34"
"low bq, low freq, many artifacts, many samples",UPN2_071,17,7578249,A,C,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn200Lys/c.600T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),9654,108,9854,"0,0109600162",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,73,Tolerated,"30,26","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_086,17,7578249,A,C,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn200Lys/c.600T>G|393|TP53|protein_coding|CODING|ENST00000269305|6|C),6471,66,6580,"0,0100303951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,73,Tolerated,"29,95","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_048,17,7578249,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn200Lys/c.600T>A|393|TP53|protein_coding|CODING|ENST00000269305|6|T),17673,185,17932,"0,0103167522",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,73,Tolerated,"31,33","21,78"
"low bq, low freq, many artifacts",UPN2_049,17,7578249,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn200Lys/c.600T>A|393|TP53|protein_coding|CODING|ENST00000269305|6|T),15884,168,16124,"0,0104192508",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,73,Tolerated,"31,29","20,5"
"low bq, low freq, many artifacts, many samples",UPN2_002,17,7578259,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val197Glu/c.590T>A|393|TP53|protein_coding|CODING|ENST00000269305|6|T),7560,81,7677,"0,0105509965",0,0,0,0,1,0,0,0,1,NO,NO,COSM4384929. COSM4384931. COSM44424. COSM4384930. COSM4384928,haematopoietic_and_lymphoid_tissue. skin. central_nervous_system. liver. stomach. upper_aerodigestive_tract. urinary_tract,6. 7. 1. 1. 1. 2. 1,NO,NO,NO,NO,NO,NO,"-5,39",Deleterious,0,Damaging,"31,61","24,31"
"low bq, low freq, many artifacts, many samples",UPN2_041,17,7578259,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val197Glu/c.590T>A|393|TP53|protein_coding|CODING|ENST00000269305|6|T),19640,204,19954,"0,0102235141",0,0,0,0,1,0,0,0,1,NO,NO,COSM4384929. COSM4384931. COSM44424. COSM4384930. COSM4384928,haematopoietic_and_lymphoid_tissue. skin. central_nervous_system. liver. stomach. upper_aerodigestive_tract. urinary_tract,6. 7. 1. 1. 1. 2. 1,NO,NO,NO,NO,NO,NO,"-5,39",Deleterious,0,Damaging,"31,11","18,06"
"low bq, low freq, many artifacts, many samples",UPN2_042,17,7578259,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val197Glu/c.590T>A|393|TP53|protein_coding|CODING|ENST00000269305|6|T),18150,204,18444,"0,0110605075",0,0,0,0,1,0,0,0,1,NO,NO,COSM4384929. COSM4384931. COSM44424. COSM4384930. COSM4384928,haematopoietic_and_lymphoid_tissue. skin. central_nervous_system. liver. stomach. upper_aerodigestive_tract. urinary_tract,6. 7. 1. 1. 1. 2. 1,NO,NO,NO,NO,NO,NO,"-5,39",Deleterious,0,Damaging,"31,13","18,99"
"low bq, low freq, many artifacts, many samples",UPN2_043,17,7578259,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val197Glu/c.590T>A|393|TP53|protein_coding|CODING|ENST00000269305|6|T),10287,117,10458,"0,0111876076",0,0,0,0,1,0,0,0,1,NO,NO,COSM4384929. COSM4384931. COSM44424. COSM4384930. COSM4384928,haematopoietic_and_lymphoid_tissue. skin. central_nervous_system. liver. stomach. upper_aerodigestive_tract. urinary_tract,6. 7. 1. 1. 1. 2. 1,NO,NO,NO,NO,NO,NO,"-5,39",Deleterious,0,Damaging,"31,31","20,01"
"low bq, low freq, many artifacts, many samples",UPN2_045,17,7578259,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val197Glu/c.590T>A|393|TP53|protein_coding|CODING|ENST00000269305|6|T),14319,149,14555,"0,0102370319",0,0,0,0,1,0,0,0,1,NO,NO,COSM4384929. COSM4384931. COSM44424. COSM4384930. COSM4384928,haematopoietic_and_lymphoid_tissue. skin. central_nervous_system. liver. stomach. upper_aerodigestive_tract. urinary_tract,6. 7. 1. 1. 1. 2. 1,NO,NO,NO,NO,NO,NO,"-5,39",Deleterious,0,Damaging,"31,07","20,01"
"low bq, low freq, many artifacts, many samples",UPN2_046,17,7578259,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val197Glu/c.590T>A|393|TP53|protein_coding|CODING|ENST00000269305|6|T),14095,175,14349,"0,0121959718",0,0,0,0,1,0,0,0,1,NO,NO,COSM4384929. COSM4384931. COSM44424. COSM4384930. COSM4384928,haematopoietic_and_lymphoid_tissue. skin. central_nervous_system. liver. stomach. upper_aerodigestive_tract. urinary_tract,6. 7. 1. 1. 1. 2. 1,NO,NO,NO,NO,NO,NO,"-5,39",Deleterious,0,Damaging,"31,03","23,54"
"low bq, low freq, many artifacts, many samples",UPN2_048,17,7578259,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val197Glu/c.590T>A|393|TP53|protein_coding|CODING|ENST00000269305|6|T),17708,185,17967,"0,010296655",0,0,0,0,1,0,0,0,1,NO,NO,COSM4384929. COSM4384931. COSM44424. COSM4384930. COSM4384928,haematopoietic_and_lymphoid_tissue. skin. central_nervous_system. liver. stomach. upper_aerodigestive_tract. urinary_tract,6. 7. 1. 1. 1. 2. 1,NO,NO,NO,NO,NO,NO,"-5,39",Deleterious,0,Damaging,"31,24","18,9"
"low bq, low freq, many artifacts, many samples",UPN2_049,17,7578259,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val197Glu/c.590T>A|393|TP53|protein_coding|CODING|ENST00000269305|6|T),15859,198,16159,"0,0122532335",0,0,0,0,1,0,0,0,1,NO,NO,COSM4384929. COSM4384931. COSM44424. COSM4384930. COSM4384928,haematopoietic_and_lymphoid_tissue. skin. central_nervous_system. liver. stomach. upper_aerodigestive_tract. urinary_tract,6. 7. 1. 1. 1. 2. 1,NO,NO,NO,NO,NO,NO,"-5,39",Deleterious,0,Damaging,"31,15","19,35"
"low bq, low freq, many artifacts, many samples",UPN2_050,17,7578259,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val197Glu/c.590T>A|393|TP53|protein_coding|CODING|ENST00000269305|6|T),14425,148,14650,"0,0101023891",0,0,0,0,1,0,0,0,1,NO,NO,COSM4384929. COSM4384931. COSM44424. COSM4384930. COSM4384928,haematopoietic_and_lymphoid_tissue. skin. central_nervous_system. liver. stomach. upper_aerodigestive_tract. urinary_tract,6. 7. 1. 1. 1. 2. 1,NO,NO,NO,NO,NO,NO,"-5,39",Deleterious,0,Damaging,"31,17","18,7"
"low bq, low freq, many artifacts, many samples",UPN2_052,17,7578259,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val197Glu/c.590T>A|393|TP53|protein_coding|CODING|ENST00000269305|6|T),7190,89,7311,"0,0121734373",0,0,0,0,1,0,0,0,1,NO,NO,COSM4384929. COSM4384931. COSM44424. COSM4384930. COSM4384928,haematopoietic_and_lymphoid_tissue. skin. central_nervous_system. liver. stomach. upper_aerodigestive_tract. urinary_tract,6. 7. 1. 1. 1. 2. 1,NO,NO,NO,NO,NO,NO,"-5,39",Deleterious,0,Damaging,"30,92","23,51"
"low bq, low freq, many artifacts, many samples",UPN2_055,17,7578259,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val197Glu/c.590T>A|393|TP53|protein_coding|CODING|ENST00000269305|6|T),15667,163,15909,"0,0102457728",0,0,0,0,1,0,0,0,1,NO,NO,COSM4384929. COSM4384931. COSM44424. COSM4384930. COSM4384928,haematopoietic_and_lymphoid_tissue. skin. central_nervous_system. liver. stomach. upper_aerodigestive_tract. urinary_tract,6. 7. 1. 1. 1. 2. 1,NO,NO,NO,NO,NO,NO,"-5,39",Deleterious,0,Damaging,"31,1","18,69"
"low bq, low freq, many artifacts, many samples",UPN2_057,17,7578259,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val197Glu/c.590T>A|393|TP53|protein_coding|CODING|ENST00000269305|6|T),13752,149,13985,"0,0106542724",0,0,0,0,1,0,0,0,1,NO,NO,COSM4384929. COSM4384931. COSM44424. COSM4384930. COSM4384928,haematopoietic_and_lymphoid_tissue. skin. central_nervous_system. liver. stomach. upper_aerodigestive_tract. urinary_tract,6. 7. 1. 1. 1. 2. 1,NO,NO,NO,NO,NO,NO,"-5,39",Deleterious,0,Damaging,"31,02","20,89"
"low bq, low freq, many artifacts, many samples",UPN2_013,17,7578259,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val197Glu/c.590T>A|393|TP53|protein_coding|CODING|ENST00000269305|6|T),4890,54,4974,"0,0108564536",0,0,0,0,1,0,0,0,1,NO,NO,COSM4384929. COSM4384931. COSM44424. COSM4384930. COSM4384928,haematopoietic_and_lymphoid_tissue. skin. central_nervous_system. liver. stomach. upper_aerodigestive_tract. urinary_tract,6. 7. 1. 1. 1. 2. 1,NO,NO,NO,NO,NO,NO,"-5,39",Deleterious,0,Damaging,"31,75","18,63"
"low bq, low freq, many artifacts",UPN2_079,17,7578259,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val197Glu/c.590T>A|393|TP53|protein_coding|CODING|ENST00000269305|6|T),6924,76,7039,"0,0107969882",0,0,0,0,1,0,0,0,1,NO,NO,COSM4384929. COSM4384931. COSM44424. COSM4384930. COSM4384928,haematopoietic_and_lymphoid_tissue. skin. central_nervous_system. liver. stomach. upper_aerodigestive_tract. urinary_tract,6. 7. 1. 1. 1. 2. 1,NO,NO,NO,NO,NO,NO,"-5,39",Deleterious,0,Damaging,"30,35","19,68"
"inspected, many artifacts",UPN2_044,17,7578260,C,T,missense_variant(MODERATE|MISSENSE|Gtg/Atg|p.Val197Met/c.589G>A|393|TP53|protein_coding|CODING|ENST00000269305|6|T),5254,76,5351,"0,0142029527",0,0,0,0,1,1,0,1,3,NO,NO,"COSM3712580, COSM43779, COSM3712581, COSM3712579, COSM3712578","pancreas, upper_aerodigestive_tract, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, urinary_tract","5, 10, 1, 5, 2, 1, 1",NO,NO,NO,NO,NO,NO,"-2,22",Neutral,"0,028",Damaging,"32,62","31,67"
"low bq, low freq, many artifacts, many samples",UPN2_043,17,7578268,A,T,missense_variant(MODERATE|MISSENSE|cTt/cAt|p.Leu194His/c.581T>A|393|TP53|protein_coding|CODING|ENST00000269305|6|T),10290,109,10466,"0,0104146761",0,0,0,0,1,0,0,0,1,NO,NO,COSM43623,haematopoietic_and_lymphoid_tissue. large_intestine. oesophagus,3. 1. 1,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,"32,49","17,21"
"low bq, low freq, many artifacts, many samples",UPN2_005,17,7578268,A,T,missense_variant(MODERATE|MISSENSE|cTt/cAt|p.Leu194His/c.581T>A|393|TP53|protein_coding|CODING|ENST00000269305|6|T),2448,27,2488,"0,01085209",0,0,0,0,1,0,0,0,1,NO,NO,COSM43623,haematopoietic_and_lymphoid_tissue. large_intestine. oesophagus,3. 1. 1,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,"33,04","20,19"
"low bq, low freq, many artifacts, many samples",UPN2_047,17,7578268,A,T,missense_variant(MODERATE|MISSENSE|cTt/cAt|p.Leu194His/c.581T>A|393|TP53|protein_coding|CODING|ENST00000269305|6|T),21639,220,21966,"0,0100154785",0,0,0,0,1,0,0,0,1,NO,NO,COSM43623,haematopoietic_and_lymphoid_tissue. large_intestine. oesophagus,3. 1. 1,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,"32,45","19,04"
"low bq, low freq, many artifacts, many samples",UPN2_049,17,7578268,A,T,missense_variant(MODERATE|MISSENSE|cTt/cAt|p.Leu194His/c.581T>A|393|TP53|protein_coding|CODING|ENST00000269305|6|T),15912,168,16166,"0,0103921811",0,0,0,0,1,0,0,0,1,NO,NO,COSM43623,haematopoietic_and_lymphoid_tissue. large_intestine. oesophagus,3. 1. 1,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,"32,5","19,7"
"low bq, low freq, many artifacts, many samples",UPN2_050,17,7578268,A,T,missense_variant(MODERATE|MISSENSE|cTt/cAt|p.Leu194His/c.581T>A|393|TP53|protein_coding|CODING|ENST00000269305|6|T),14414,163,14657,"0,0111209661",0,0,0,0,1,0,0,0,1,NO,NO,COSM43623,haematopoietic_and_lymphoid_tissue. large_intestine. oesophagus,3. 1. 1,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,"32,5","19,14"
"low bq, low freq, many artifacts, many samples",UPN2_011,17,7578268,A,T,missense_variant(MODERATE|MISSENSE|cTt/cAt|p.Leu194His/c.581T>A|393|TP53|protein_coding|CODING|ENST00000269305|6|T),15694,201,15985,"0,0125742884",0,0,0,0,1,0,0,0,1,NO,NO,COSM43623,haematopoietic_and_lymphoid_tissue. large_intestine. oesophagus,3. 1. 1,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,"33,04",22
"low bq, low freq, many artifacts, many samples",UPN2_057,17,7578268,A,T,missense_variant(MODERATE|MISSENSE|cTt/cAt|p.Leu194His/c.581T>A|393|TP53|protein_coding|CODING|ENST00000269305|6|T),13790,149,13995,"0,0106466595",0,0,0,0,1,0,0,0,1,NO,NO,COSM43623,haematopoietic_and_lymphoid_tissue. large_intestine. oesophagus,3. 1. 1,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,"32,48","17,13"
"low bq, low freq, many artifacts",UPN2_058,17,7578268,A,T,missense_variant(MODERATE|MISSENSE|cTt/cAt|p.Leu194His/c.581T>A|393|TP53|protein_coding|CODING|ENST00000269305|6|T),19669,201,19967,"0,0100666099",0,0,0,0,1,0,0,0,1,NO,NO,COSM43623,haematopoietic_and_lymphoid_tissue. large_intestine. oesophagus,3. 1. 1,NO,NO,NO,NO,NO,NO,"-6,69",Deleterious,0,Damaging,"32,5","19,27"
"inspected, many artifacts",UPN2_093,17,7578272,G,A,missense_variant(MODERATE|MISSENSE|Cat/Tat|p.His193Tyr/c.577C>T|393|TP53|protein_coding|CODING|ENST00000269305|6|A),6106,72,6188,"0,0116354234",0,0,0,0,1,1,0,1,3,NO,NO,"COSM10672, COSM3388200, COSM437529, COSM437530, COSM1731184","adrenal_gland, biliary_tract, bone, breast, central_nervous_system, haematopoietic_and_lymphoid_tissue, kidney, large_intestine, liver, lung, oesophagus, ovary, pancreas, soft_tissue, stomach, thymus, upper_aerodigestive_tract, urinary_tract","5, 1, 5, 13, 9, 11, 3, 15, 4, 6, 19, 6, 26, 1, 5, 5, 4, 3",NO,NO,NO,NO,NO,NO,"-5,74",Deleterious,0,Damaging,"33,59","34,5"
"low freq, many samples, no database, strandbias",UPN2_001,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),5661,548,6246,"0,0877361511",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,59","31,33"
"low freq, many samples, no database, strandbias",UPN2_014,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),9853,556,10451,"0,0532006507",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,89","31,43"
"low freq, many samples, no database, strandbias",UPN2_015,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),15278,675,16034,"0,0420980417",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,97","31,53"
"low freq, many samples, no database, strandbias",UPN2_016,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),7564,355,7951,"0,0446484719",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"34,06","31,83"
"low freq, many samples, no database, strandbias",UPN2_017,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),4950,249,5219,"0,0477102893",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,94","31,93"
"low freq, many samples, no database, strandbias",UPN2_018,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),7687,353,8080,"0,0436881188",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,97","31,85"
"low freq, many samples, no database, strandbias",UPN2_019,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),7982,454,8473,"0,0535819662",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,97","31,46"
"low freq, many samples, no database, strandbias",UPN2_020,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),5549,344,5925,"0,0580590717",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,75","31,66"
"low freq, many samples, no database, strandbias",UPN2_021,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),7954,492,8481,"0,0580120269",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,94","31,63"
"low freq, many samples, no database, strandbias",UPN2_002,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),8437,799,9279,"0,0861084169",1,0,0,0,1,1,0,0,3,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,76","31,46"
"low freq, many samples, no database, strandbias",UPN2_003,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),1567,143,1715,"0,0833819242",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,6","31,57"
"low freq, many samples, no database, strandbias",UPN2_022,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),10775,617,11446,"0,0539052944",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,91","31,68"
"low freq, many samples, no database, strandbias",UPN2_023,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),11128,712,11901,"0,0598269053",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,77","31,63"
"low freq, many samples, no database, strandbias",UPN2_041,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),26862,649,27671,"0,0234541578",0,0,0,0,1,1,0,1,3,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,55","31,85"
"low freq, many samples, no database, strandbias",UPN2_024,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),4732,230,4984,"0,0461476726",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,81","31,86"
"low freq, many samples, no database, strandbias",UPN2_025,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),13509,721,14307,"0,0503949116",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,99","31,72"
"low freq, many samples, no database, strandbias",UPN2_026,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),11570,692,12318,"0,056177951",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,93","31,73"
"low freq, many samples, no database, strandbias",UPN2_004,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),2705,94,2818,"0,0333569908",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"34,44","31,17"
"low freq, many samples, no database, strandbias",UPN2_027,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),12516,758,13333,"0,0568514213",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,96","31,66"
"low freq, many samples, no database, strandbias",UPN2_089,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),10711,246,10976,"0,0224125364",0,0,0,0,1,1,0,1,3,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"34,04","31,75"
"low freq, many samples, no database, strandbias",UPN2_042,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),21902,677,22721,"0,0297962238",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,44","31,55"
"low freq, many samples, no database, strandbias",UPN2_028,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),10025,442,10509,"0,0420591874",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"34,08","31,5"
"low freq, many samples, no database, strandbias",UPN2_043,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),11499,403,11977,"0,033647825",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,43","31,38"
"low freq, many samples, no database, strandbias",UPN2_044,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),7327,242,7612,"0,0317919075",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,65","31,55"
"low freq, many samples, no database, strandbias",UPN2_029,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),10624,600,11265,"0,0532623169",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,77","31,56"
"low freq, many samples, no database, strandbias",UPN2_030,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),12955,701,13721,"0,0510895707",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,96","31,78"
"low freq, many samples, no database, strandbias",UPN2_031,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),8771,425,9246,"0,0459658231",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,95","31,64"
"low freq, many samples, no database, strandbias",UPN2_005,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),2197,267,2478,"0,107748184",0,1,0,0,1,1,0,0,3,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,56","31,67"
"low freq, many samples, no database, strandbias",UPN2_045,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),13707,405,14189,"0,0285432377",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,23","31,64"
"low freq, many samples, no database, strandbias",UPN2_032,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),4573,231,4821,"0,0479153703",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,8","31,52"
"low freq, many samples, no database, strandbias",UPN2_046,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),19478,701,20333,"0,034475975",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,67","31,69"
"low freq, many samples, no database, strandbias",UPN2_033,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),8633,384,9058,"0,0423934643",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"34,03","31,51"
"low freq, many samples, no database, strandbias",UPN2_034,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),3294,149,3458,"0,0430884905",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,34,"31,82"
"low freq, many samples, no database, strandbias",UPN2_047,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),25084,925,26168,"0,0353485173",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,43","31,56"
"low freq, many samples, no database, strandbias",UPN2_048,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),23642,799,24590,"0,0324928833",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,57","31,56"
"low freq, many samples, no database, strandbias",UPN2_035,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),17683,994,18750,"0,0530133333",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,93","31,62"
"low freq, many samples, no database, strandbias",UPN2_036,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),33418,1873,35468,"0,0528081651",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,89","31,52"
"low freq, many samples, no database, strandbias",UPN2_006,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),7323,612,7968,"0,0768072289",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,87","31,58"
"low freq, many samples, no database, strandbias",UPN2_049,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),27530,652,28384,"0,0229706877",0,0,0,0,1,1,0,1,3,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,78","31,66"
"low freq, many samples, no database, strandbias",UPN2_050,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),17509,375,17989,"0,0208460726",0,0,0,0,1,1,0,1,3,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,41","31,91"
"low freq, many samples, no database, strandbias",UPN2_037,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),15655,1038,16761,"0,0619294791",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,84","31,56"
"low freq, many samples, no database, strandbias",UPN2_051,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),16968,387,17489,"0,0221281949",0,0,0,0,1,1,0,1,3,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,76","32,1"
"low freq, many samples, no database, strandbias",UPN2_052,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),9553,214,9818,"0,0217966999",0,0,0,0,1,1,0,1,3,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,56","31,69"
"low freq, many samples, no database, strandbias",UPN2_038,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),17850,1101,19054,"0,0577831426",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,83","31,59"
"low freq, many samples, no database, strandbias",UPN2_039,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),31498,1685,33321,"0,0505687104",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,34,"31,63"
"low freq, many samples, no database, strandbias",UPN2_053,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),22820,701,23653,"0,0296368325",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,71","31,58"
"low freq, many samples, no database, strandbias",UPN2_054,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),12451,270,12801,"0,0210921022",0,0,0,0,1,1,0,1,3,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,78","31,65"
"low freq, many samples, no database, strandbias",UPN2_007,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),17180,1758,19043,"0,092317387",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,61","31,41"
"low freq, many samples, no database, strandbias",UPN2_008,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),24087,2413,26612,"0,0906733804",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,61","31,44"
"low freq, many samples, no database, strandbias",UPN2_009,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),20288,1805,22190,"0,0813429473",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,6","31,47"
"low freq, many samples, no database, strandbias",UPN2_010,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),14360,1229,15673,"0,0784151088",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,71","31,56"
"low freq, many samples, no database, strandbias",UPN2_011,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),14804,1497,16360,"0,0915036675",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,51","31,52"
"low freq, many samples, no database, strandbias",UPN2_055,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),20132,623,20881,"0,0298357358",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,55","31,68"
"low freq, many samples, no database, strandbias",UPN2_056,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),13977,338,14410,"0,0234559334",0,0,0,0,1,1,0,1,3,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,79","31,85"
"low freq, many samples, no database, strandbias",UPN2_090,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),6848,116,6979,"0,0166212924",0,0,0,0,1,1,0,1,3,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,8","31,7"
"low freq, many samples, no database, strandbias",UPN2_057,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),20507,646,21308,"0,0303172517",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,69","31,69"
"low freq, many samples, no database, strandbias",UPN2_058,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),21429,1094,22653,"0,0482938242",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,38","31,28"
"low freq, many samples, no database, strandbias",UPN2_059,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),10135,913,11101,"0,0822448428",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,22","31,39"
"low freq, many samples, no database, strandbias",UPN2_012,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),7698,793,8524,"0,0930314406",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,56","31,55"
"low freq, many samples, no database, strandbias",UPN2_060,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),10169,1027,11237,"0,0913945003",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,29","31,33"
"low freq, many samples, no database, strandbias",UPN2_040,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),15344,1022,16458,"0,0620974602",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,69","31,55"
"low freq, many samples, no database, strandbias",UPN2_013,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),4688,468,5176,"0,0904173107",1,0,0,0,1,1,0,0,3,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,44","31,53"
"low freq, many samples, no database, strandbias",UPN2_091,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),7901,239,8168,"0,0292605289",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,77","31,6"
"low freq, many samples, no database, strandbias",UPN2_092,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),5393,137,5541,"0,0247247789",0,0,0,0,1,1,0,1,3,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,82","31,64"
"low freq, many samples, no database, strandbias",UPN2_093,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),6891,169,7076,"0,02388355",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,85","31,82"
"low freq, many samples, no database, strandbias",UPN2_061,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),10736,1115,11891,"0,0937683963",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,3","31,41"
"low freq, many samples, no database, strandbias",UPN2_062,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),10559,1015,11613,"0,0874020494",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,46","31,5"
"low freq, many samples, no database, strandbias",UPN2_063,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),11932,1327,13293,"0,0998269766",0,1,0,0,1,1,0,0,3,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,26","31,39"
"low freq, many samples, no database, strandbias",UPN2_064,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),13924,1615,15578,"0,1036718449",0,1,0,0,1,1,0,0,3,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,14","31,52"
"low freq, many samples, no database, strandbias",UPN2_065,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),8577,837,9428,"0,0887781078",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,06","31,39"
"low freq, many samples, no database, strandbias",UPN2_066,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),8197,872,9097,"0,0958557766",0,1,0,0,1,1,0,0,3,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,01","31,51"
"low freq, many samples, no database, strandbias",UPN2_067,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),8452,875,9360,"0,093482906",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,15","31,65"
"low freq, many samples, no database, strandbias",UPN2_068,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),8239,707,8977,"0,078756823",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,29","31,36"
"low freq, many samples, no database, strandbias",UPN2_069,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),10458,913,11406,"0,08004559",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,42","31,52"
"low freq, many samples, no database, strandbias",UPN2_070,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),6858,666,7541,"0,0883171993",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,3","31,27"
"low freq, many samples, no database, strandbias",UPN2_071,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),8699,791,9514,"0,0831406349",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,45","31,55"
"low freq, many samples, no database, strandbias",UPN2_072,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),11259,1026,12333,"0,0831914376",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,42","31,48"
"low freq, many samples, no database, strandbias",UPN2_073,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),7685,726,8445,"0,0859680284",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,3","31,44"
"low freq, many samples, no database, strandbias",UPN2_074,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),5533,660,6205,"0,106365834",0,1,0,0,1,1,0,0,3,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,11","31,39"
"low freq, many samples, no database, strandbias",UPN2_075,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),12030,1086,13154,"0,0825604379",1,0,0,0,1,1,0,0,3,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,46","31,42"
"low freq, many samples, no database, strandbias",UPN2_076,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),7963,782,8774,"0,089126966",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,35","31,47"
"low freq, many samples, no database, strandbias",UPN2_077,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),7491,713,8237,"0,086560641",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,26","31,38"
"low freq, many samples, no database, strandbias",UPN2_078,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),9772,930,10725,"0,0867132867",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,33","31,55"
"low freq, many samples, no database, strandbias",UPN2_079,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),5898,521,6445,"0,0808378588",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,29","31,34"
"low freq, many samples, no database, strandbias",UPN2_080,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),9570,957,10551,"0,0907023031",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,38","31,39"
"low freq, many samples, no database, strandbias",UPN2_081,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),14897,1332,16272,"0,0818584071",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,22","31,53"
"low freq, many samples, no database, strandbias",UPN2_082,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),10083,970,11093,"0,0874425313",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,07","31,29"
"low freq, many samples, no database, strandbias",UPN2_083,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),11080,1067,12184,"0,0875738674",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,33","31,39"
"low freq, many samples, no database, strandbias",UPN2_084,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),10843,914,11795,"0,0774904621",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,37","31,63"
"low freq, many samples, no database, strandbias",UPN2_085,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),6735,637,7396,"0,0861276366",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,15","31,33"
"low freq, many samples, no database, strandbias",UPN2_086,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),4745,532,5295,"0,1004721435",0,1,0,0,1,1,0,0,3,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,06","31,4"
"low freq, many samples, no database, strandbias",UPN2_087,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),11079,1054,12173,"0,0865850653",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,19","31,35"
"low freq, many samples, no database, strandbias",UPN2_088,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),7695,865,8589,"0,1007102107",0,1,0,0,1,1,0,0,3,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,18","31,54"
"low freq, many samples, no database, strandbias",UPN2_094,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),9391,221,9632,"0,0229443522",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,89","31,77"
"low freq, many samples, no database, strandbias",UPN2_095,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),8273,220,8519,"0,0258246273",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,79","31,94"
"low freq, many samples, no database, strandbias",UPN2_096,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),7641,183,7838,"0,0233477928",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,54","31,64"
"low freq, many samples, no database, strandbias",UPN2_097,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),8805,239,9059,"0,0263826029",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,74","31,67"
"low freq, many samples, no database, strandbias",UPN2_098,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),8778,220,9014,"0,0244064788",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,82","31,87"
"low freq, many samples, no database, strandbias",UPN2_099,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),4735,103,4843,"0,0212678092",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,83","31,53"
"low freq, many samples, no database, strandbias",UPN2_100,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),8601,155,8767,"0,0176799361",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,98","32,05"
"low freq, many samples, no database, strandbias",UPN2_101,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),8385,143,8547,"0,0167310167",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,89","31,94"
"low freq, many samples, no database, strandbias",UPN2_102,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),8066,182,8270,"0,0220072551",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,87","31,93"
"low freq, many samples, no database, strandbias",UPN2_103,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),8737,174,8923,"0,0195001681",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"34,02","31,68"
"low freq, many samples, no database, strandbias",UPN2_104,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),9183,248,9454,"0,0262322826",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,8","31,77"
"low freq, many samples, no database, strandbias",UPN2_105,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),8311,156,8486,"0,0183832194",0,0,0,0,1,1,0,1,3,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,98","32,15"
"low freq, many samples, no database, strandbias",UPN2_106,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),14381,242,14648,"0,0165210268",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"34,03","31,74"
"low freq, many samples, no database, strandbias",UPN2_107,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),13717,322,14065,"0,0228937078",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,62","31,86"
"low freq, many samples, no database, strandbias",UPN2_108,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),13308,278,13614,"0,0204201557",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,78","31,92"
"low freq, many samples, no database, strandbias",UPN2_109,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),11633,203,11857,"0,0171206882",0,0,0,0,1,1,0,0,2,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,83","31,91"
"low freq, many samples, no database, strandbias",UPN2_110,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),10840,187,11044,"0,0169322709",0,0,0,0,1,1,0,1,3,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"33,68","32,15"
"low freq, many samples, no database, strandbias",UPN2_111,17,7578394,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His179Arg/c.536A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),11496,223,11736,"0,0190013633",0,0,0,0,1,1,0,1,3,NO,NO,"COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4",NO,NO,NO,NO,NO,NO,"-7,66",Deleterious,0,Damaging,"34,06","31,86"
"low bq, low freq, many artifacts, many samples",UPN2_044,17,7578397,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His178Leu/c.533A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),4876,52,4955,"0,0104944501",0,0,0,0,1,0,0,0,1,NO,NO,COSM45934,biliary_tract,1,NO,NO,NO,NO,NO,NO,"-8,18",Deleterious,1,Damaging,"34,47","17,87"
"low bq, low freq, many artifacts, many samples",UPN2_058,17,7578397,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His178Leu/c.533A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),12563,147,12799,"0,0114852723",0,0,0,0,1,0,0,0,1,NO,NO,COSM45934,biliary_tract,1,NO,NO,NO,NO,NO,NO,"-8,18",Deleterious,1,Damaging,"34,45","20,48"
"inspected, homopolymer 5G, many artifacts, many samples",UPN2_032,17,7578397,TG,T,frameshift_variant(HIGH||cac/|p.His178fs/c.532delC|393|TP53|protein_coding|CODING|ENST00000269305|5|T),2995,36,3051,"0,01179941",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,rs68130327,NO,NO,NO,NO,NA,NA,NA,NA,"34,74",NA
"homopolymer 5G, many artifacts, many samples",UPN2_052,17,7578397,TG,T,frameshift_variant(HIGH||cac/|p.His178fs/c.532delC|393|TP53|protein_coding|CODING|ENST00000269305|5|T),6084,66,6184,"0,0106727038",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,rs68130327,NO,NO,NO,NO,NA,NA,NA,NA,"34,09",NA
"homopolymer 5G, many artifacts, many samples",UPN2_091,17,7578397,TG,T,frameshift_variant(HIGH||cac/|p.His178fs/c.532delC|393|TP53|protein_coding|CODING|ENST00000269305|5|T),4379,53,4448,"0,0119154676",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,rs68130327,NO,NO,NO,NO,NA,NA,NA,NA,"34,68",NA
"homopolymer 5G, many artifacts, many samples",UPN2_092,17,7578397,TG,T,frameshift_variant(HIGH||cac/|p.His178fs/c.532delC|393|TP53|protein_coding|CODING|ENST00000269305|5|T),3120,33,3164,"0,0104298357",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,rs68130327,NO,NO,NO,NO,NA,NA,NA,NA,"34,72",NA
"inspected, many artifacts",UPN2_044,17,7578398,G,A,missense_variant(MODERATE|MISSENSE|Cac/Tac|p.His178Tyr/c.532C>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),4854,54,4955,"0,0108980827",0,0,0,0,1,0,0,1,2,NO,NO,COSM44120,"haematopoietic_and_lymphoid_tissue, large_intestine, ovary, skin, stomach, vulva","1, 1, 1, 2, 1, 1",NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,"0,001",Damaging,"33,95","33,78"
"low bq, low freq, many artifacts, many samples",UPN2_065,17,7578415,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val172Gly/c.515T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),3532,42,3586,"0,0117122142",0,0,0,0,1,0,0,0,1,NO,NO,COSM707876. COSM1736031. COSM707877. COSM4859924. COSM45047,central_nervous_system. lung. liver. stomach,4. 5. 2. 1,NO,NO,NO,NO,NO,NO,"-6,47",Deleterious,0,Damaging,"29,49","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_066,17,7578415,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val172Gly/c.515T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),3262,34,3310,"0,0102719033",0,0,0,0,1,0,0,0,1,NO,NO,COSM707876. COSM1736031. COSM707877. COSM4859924. COSM45047,central_nervous_system. lung. liver. stomach,4. 5. 2. 1,NO,NO,NO,NO,NO,NO,"-6,47",Deleterious,0,Damaging,"29,37","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_069,17,7578415,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val172Gly/c.515T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),5336,55,5409,"0,0101682381",0,0,0,0,1,0,0,0,1,NO,NO,COSM707876. COSM1736031. COSM707877. COSM4859924. COSM45047,central_nervous_system. lung. liver. stomach,4. 5. 2. 1,NO,NO,NO,NO,NO,NO,"-6,47",Deleterious,0,Damaging,"29,15","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_071,17,7578415,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val172Gly/c.515T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),4612,49,4682,"0,010465613",0,0,0,0,1,0,0,0,1,NO,NO,COSM707876. COSM1736031. COSM707877. COSM4859924. COSM45047,central_nervous_system. lung. liver. stomach,4. 5. 2. 1,NO,NO,NO,NO,NO,NO,"-6,47",Deleterious,0,Damaging,"29,34","15,45"
"low bq, low freq, many artifacts, many samples",UPN2_077,17,7578415,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val172Gly/c.515T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),3496,38,3550,"0,0107042254",0,0,0,0,1,0,0,0,1,NO,NO,COSM707876. COSM1736031. COSM707877. COSM4859924. COSM45047,central_nervous_system. lung. liver. stomach,4. 5. 2. 1,NO,NO,NO,NO,NO,NO,"-6,47",Deleterious,0,Damaging,"29,31",14
"low bq, low freq, many artifacts",UPN2_086,17,7578415,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val172Gly/c.515T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),2009,21,2039,"0,0102991663",0,0,0,0,1,0,0,0,1,NO,NO,COSM707876. COSM1736031. COSM707877. COSM4859924. COSM45047,central_nervous_system. lung. liver. stomach,4. 5. 2. 1,NO,NO,NO,NO,NO,NO,"-6,47",Deleterious,0,Damaging,"29,32","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_044,17,7578422,T,A,missense_variant(MODERATE|MISSENSE|Acg/Tcg|p.Thr170Ser/c.508A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),4880,52,4948,"0,0105092967",0,0,0,0,1,0,0,0,1,NO,NO,COSM44325,prostate,1,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,41,Damaging,"33,7","17,04"
"low bq, low freq, many artifacts, many samples",UPN2_047,17,7578422,T,A,missense_variant(MODERATE|MISSENSE|Acg/Tcg|p.Thr170Ser/c.508A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),15038,155,15243,"0,010168602",0,0,0,0,1,0,0,0,1,NO,NO,COSM44325,prostate,1,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,41,Damaging,"33,82","18,07"
"low bq, low freq, many artifacts, many samples",UPN2_048,17,7578422,T,A,missense_variant(MODERATE|MISSENSE|Acg/Tcg|p.Thr170Ser/c.508A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),15444,157,15660,"0,0100255428",0,0,0,0,1,0,0,0,1,NO,NO,COSM44325,prostate,1,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,41,Damaging,"33,8","18,63"
"low bq, low freq, many artifacts, many samples",UPN2_006,17,7578422,T,A,missense_variant(MODERATE|MISSENSE|Acg/Tcg|p.Thr170Ser/c.508A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),4861,51,4927,"0,0103511264",0,0,0,0,1,0,0,0,1,NO,NO,COSM44325,prostate,1,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,41,Damaging,"33,85","22,53"
"low bq, low freq, many artifacts",UPN2_058,17,7578422,T,A,missense_variant(MODERATE|MISSENSE|Acg/Tcg|p.Thr170Ser/c.508A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),12588,130,12771,"0,0101793125",0,0,0,0,1,0,0,0,1,NO,NO,COSM44325,prostate,1,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,41,Damaging,"33,78","18,25"
"low bq, low freq, many artifacts, many samples",UPN2_001,17,7578425,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met169Leu/c.505A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),3441,40,3497,"0,0114383758",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,5,Damaging,"34,06","16,75"
"low bq, low freq, many artifacts, many samples",UPN2_041,17,7578425,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met169Leu/c.505A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),17427,192,17702,"0,0108462321",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,5,Damaging,"33,77","18,04"
"low bq, low freq, many artifacts, many samples",UPN2_042,17,7578425,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met169Leu/c.505A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),13361,148,13574,"0,0109031973",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,5,Damaging,"33,68","17,54"
"low bq, low freq, many artifacts, many samples",UPN2_044,17,7578425,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met169Leu/c.505A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),4872,58,4945,"0,0117290192",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,5,Damaging,"33,84","17,62"
"low bq, low freq, many artifacts, many samples",UPN2_046,17,7578425,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met169Leu/c.505A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),13002,136,13194,"0,0103077156",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,5,Damaging,"33,65","17,32"
"low bq, low freq, many artifacts, many samples",UPN2_047,17,7578425,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met169Leu/c.505A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),15007,159,15234,"0,01043718",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,5,Damaging,"33,72","18,03"
"low bq, low freq, many artifacts, many samples",UPN2_050,17,7578425,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met169Leu/c.505A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),10498,129,10677,"0,0120820455",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,5,Damaging,"33,71","19,32"
"low bq, low freq, many artifacts, many samples",UPN2_051,17,7578425,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met169Leu/c.505A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),12015,126,12188,"0,0103380374",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,5,Damaging,"33,76","17,07"
"low bq, low freq, many artifacts, many samples",UPN2_054,17,7578425,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met169Leu/c.505A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),8752,119,8920,"0,0133408072",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,5,Damaging,"33,66","19,13"
"low bq, low freq, many artifacts, many samples",UPN2_055,17,7578425,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met169Leu/c.505A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),12745,152,12958,"0,0117302053",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,5,Damaging,"33,72","18,12"
"low bq, low freq, many artifacts, many samples",UPN2_057,17,7578425,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met169Leu/c.505A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),14143,151,14366,"0,0105109286",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,5,Damaging,"33,72","17,3"
"low bq, low freq, many artifacts",UPN2_058,17,7578425,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met169Leu/c.505A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),12585,143,12762,"0,0112051403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,5,Damaging,"33,69","18,51"
"low bq, low freq, many artifacts",UPN2_065,17,7578426,G,C,missense_variant(MODERATE|MISSENSE|caC/caG|p.His168Gln/c.504C>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),3536,38,3582,"0,0106085985",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,51",Deleterious,1,Damaging,"32,57",14
"low bq, low freq, many artifacts, many samples",UPN2_041,17,7578427,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His168Leu/c.503A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),17387,244,17695,"0,013789206",0,0,0,0,1,0,0,0,1,NO,NO,COSM562629. COSM44801. COSM1649383. COSM562630. COSM5029896,bone. breast. large_intestine. lung. oesophagus,5. 1. 2. 1. 1,NO,NO,NO,NO,NO,NO,"-10,42",Deleterious,0,Damaging,"33,63","20,18"
"low bq, low freq, many artifacts, many samples",UPN2_042,17,7578427,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His168Leu/c.503A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),13358,160,13572,"0,0117889773",0,0,0,0,1,0,0,0,1,NO,NO,COSM562629. COSM44801. COSM1649383. COSM562630. COSM5029896,bone. breast. large_intestine. lung. oesophagus,5. 1. 2. 1. 1,NO,NO,NO,NO,NO,NO,"-10,42",Deleterious,0,Damaging,"33,55","18,88"
"low bq, low freq, many artifacts, many samples",UPN2_043,17,7578427,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His168Leu/c.503A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),6672,77,6776,"0,0113636364",0,0,0,0,1,0,0,0,1,NO,NO,COSM562629. COSM44801. COSM1649383. COSM562630. COSM5029896,bone. breast. large_intestine. lung. oesophagus,5. 1. 2. 1. 1,NO,NO,NO,NO,NO,NO,"-10,42",Deleterious,0,Damaging,"33,65","19,22"
"low bq, low freq, many artifacts, many samples",UPN2_044,17,7578427,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His168Leu/c.503A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),4856,69,4945,"0,0139534884",0,0,0,0,1,0,0,0,1,NO,NO,COSM562629. COSM44801. COSM1649383. COSM562630. COSM5029896,bone. breast. large_intestine. lung. oesophagus,5. 1. 2. 1. 1,NO,NO,NO,NO,NO,NO,"-10,42",Deleterious,0,Damaging,"33,66","21,61"
"low bq, low freq, many artifacts, many samples",UPN2_045,17,7578427,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His168Leu/c.503A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),6843,81,6944,"0,0116647465",0,0,0,0,1,0,0,0,1,NO,NO,COSM562629. COSM44801. COSM1649383. COSM562630. COSM5029896,bone. breast. large_intestine. lung. oesophagus,5. 1. 2. 1. 1,NO,NO,NO,NO,NO,NO,"-10,42",Deleterious,0,Damaging,"33,82","18,57"
"low bq, low freq, many artifacts, many samples",UPN2_046,17,7578427,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His168Leu/c.503A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),13007,144,13190,"0,0109173616",0,0,0,0,1,0,0,0,1,NO,NO,COSM562629. COSM44801. COSM1649383. COSM562630. COSM5029896,bone. breast. large_intestine. lung. oesophagus,5. 1. 2. 1. 1,NO,NO,NO,NO,NO,NO,"-10,42",Deleterious,0,Damaging,"33,64","17,72"
"low bq, low freq, many artifacts, many samples",UPN2_047,17,7578427,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His168Leu/c.503A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),14985,175,15227,"0,0114927432",0,0,0,0,1,0,0,0,1,NO,NO,COSM562629. COSM44801. COSM1649383. COSM562630. COSM5029896,bone. breast. large_intestine. lung. oesophagus,5. 1. 2. 1. 1,NO,NO,NO,NO,NO,NO,"-10,42",Deleterious,0,Damaging,"33,61","18,3"
"low bq, low freq, many artifacts, many samples",UPN2_048,17,7578427,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His168Leu/c.503A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),15404,165,15646,"0,0105458264",0,0,0,0,1,0,0,0,1,NO,NO,COSM562629. COSM44801. COSM1649383. COSM562630. COSM5029896,bone. breast. large_intestine. lung. oesophagus,5. 1. 2. 1. 1,NO,NO,NO,NO,NO,NO,"-10,42",Deleterious,0,Damaging,"33,54","18,03"
"low bq, low freq, many artifacts, many samples",UPN2_049,17,7578427,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His168Leu/c.503A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),19923,267,20296,"0,0131553015",0,0,0,0,1,0,0,0,1,NO,NO,COSM562629. COSM44801. COSM1649383. COSM562630. COSM5029896,bone. breast. large_intestine. lung. oesophagus,5. 1. 2. 1. 1,NO,NO,NO,NO,NO,NO,"-10,42",Deleterious,0,Damaging,"33,63","19,45"
"low bq, low freq, many artifacts, many samples",UPN2_050,17,7578427,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His168Leu/c.503A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),10481,132,10675,"0,0123653396",0,0,0,0,1,0,0,0,1,NO,NO,COSM562629. COSM44801. COSM1649383. COSM562630. COSM5029896,bone. breast. large_intestine. lung. oesophagus,5. 1. 2. 1. 1,NO,NO,NO,NO,NO,NO,"-10,42",Deleterious,0,Damaging,"33,56","18,86"
"low bq, low freq, many artifacts, many samples",UPN2_051,17,7578427,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His168Leu/c.503A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),11991,155,12186,"0,0127195142",0,0,0,0,1,0,0,0,1,NO,NO,COSM562629. COSM44801. COSM1649383. COSM562630. COSM5029896,bone. breast. large_intestine. lung. oesophagus,5. 1. 2. 1. 1,NO,NO,NO,NO,NO,NO,"-10,42",Deleterious,0,Damaging,"33,64","17,65"
"low bq, low freq, many artifacts, many samples",UPN2_052,17,7578427,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His168Leu/c.503A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),6052,92,6168,"0,0149156939",0,0,0,0,1,0,0,0,1,NO,NO,COSM562629. COSM44801. COSM1649383. COSM562630. COSM5029896,bone. breast. large_intestine. lung. oesophagus,5. 1. 2. 1. 1,NO,NO,NO,NO,NO,NO,"-10,42",Deleterious,0,Damaging,"33,7","17,64"
"low bq, low freq, many artifacts, many samples",UPN2_053,17,7578427,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His168Leu/c.503A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),15844,167,16089,"0,0103797626",0,0,0,0,1,0,0,0,1,NO,NO,COSM562629. COSM44801. COSM1649383. COSM562630. COSM5029896,bone. breast. large_intestine. lung. oesophagus,5. 1. 2. 1. 1,NO,NO,NO,NO,NO,NO,"-10,42",Deleterious,0,Damaging,"33,67","17,7"
"low bq, low freq, many artifacts, many samples",UPN2_054,17,7578427,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His168Leu/c.503A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),8767,118,8918,"0,0132316663",0,0,0,0,1,0,0,0,1,NO,NO,COSM562629. COSM44801. COSM1649383. COSM562630. COSM5029896,bone. breast. large_intestine. lung. oesophagus,5. 1. 2. 1. 1,NO,NO,NO,NO,NO,NO,"-10,42",Deleterious,0,Damaging,"33,63","20,08"
"low bq, low freq, many artifacts, many samples",UPN2_009,17,7578427,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His168Leu/c.503A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),12024,125,12180,"0,0102627258",0,0,0,0,1,0,0,0,1,NO,NO,COSM562629. COSM44801. COSM1649383. COSM562630. COSM5029896,bone. breast. large_intestine. lung. oesophagus,5. 1. 2. 1. 1,NO,NO,NO,NO,NO,NO,"-10,42",Deleterious,0,Damaging,"34,23","17,34"
"low bq, low freq, many artifacts, many samples",UPN2_011,17,7578427,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His168Leu/c.503A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),8425,86,8541,"0,0100690786",0,0,0,0,1,0,0,0,1,NO,NO,COSM562629. COSM44801. COSM1649383. COSM562630. COSM5029896,bone. breast. large_intestine. lung. oesophagus,5. 1. 2. 1. 1,NO,NO,NO,NO,NO,NO,"-10,42",Deleterious,0,Damaging,"34,31","18,77"
"low bq, low freq, many artifacts, many samples",UPN2_055,17,7578427,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His168Leu/c.503A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),12742,159,12956,"0,0122723063",0,0,0,0,1,0,0,0,1,NO,NO,COSM562629. COSM44801. COSM1649383. COSM562630. COSM5029896,bone. breast. large_intestine. lung. oesophagus,5. 1. 2. 1. 1,NO,NO,NO,NO,NO,NO,"-10,42",Deleterious,0,Damaging,"33,71","18,65"
"low bq, low freq, many artifacts, many samples",UPN2_056,17,7578427,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His168Leu/c.503A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),9728,111,9879,"0,0112359551",0,0,0,0,1,0,0,0,1,NO,NO,COSM562629. COSM44801. COSM1649383. COSM562630. COSM5029896,bone. breast. large_intestine. lung. oesophagus,5. 1. 2. 1. 1,NO,NO,NO,NO,NO,NO,"-10,42",Deleterious,0,Damaging,"33,66","19,68"
"low bq, low freq, many artifacts, many samples",UPN2_057,17,7578427,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His168Leu/c.503A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),14139,166,14361,"0,0115590836",0,0,0,0,1,0,0,0,1,NO,NO,COSM562629. COSM44801. COSM1649383. COSM562630. COSM5029896,bone. breast. large_intestine. lung. oesophagus,5. 1. 2. 1. 1,NO,NO,NO,NO,NO,NO,"-10,42",Deleterious,0,Damaging,"33,64","19,9"
"low bq, low freq, many artifacts, many samples",UPN2_058,17,7578427,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His168Leu/c.503A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),12530,182,12760,"0,0142633229",0,0,0,0,1,0,0,0,1,NO,NO,COSM562629. COSM44801. COSM1649383. COSM562630. COSM5029896,bone. breast. large_intestine. lung. oesophagus,5. 1. 2. 1. 1,NO,NO,NO,NO,NO,NO,"-10,42",Deleterious,0,Damaging,"33,66","18,16"
"low bq, low freq, many artifacts",UPN2_012,17,7578427,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His168Leu/c.503A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),4383,58,4462,"0,0129986553",0,0,0,0,1,0,0,0,1,NO,NO,COSM562629. COSM44801. COSM1649383. COSM562630. COSM5029896,bone. breast. large_intestine. lung. oesophagus,5. 1. 2. 1. 1,NO,NO,NO,NO,NO,NO,"-10,42",Deleterious,0,Damaging,"34,26","19,05"
"low bq, low freq, many artifacts, many samples",UPN2_004,17,7578436,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln165Leu/c.494A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),2311,24,2341,"0,010252029",0,0,0,0,1,0,0,0,1,NO,NO,COSM44850,haematopoietic_and_lymphoid_tissue. salivary_gland. soft_tissue,1. 1. 1,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,1,Damaging,"34,46","21,71"
"low bq, low freq, many artifacts, many samples",UPN2_047,17,7578436,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln165Leu/c.494A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),15013,163,15223,"0,0107074821",0,0,0,0,1,0,0,0,1,NO,NO,COSM44850,haematopoietic_and_lymphoid_tissue. salivary_gland. soft_tissue,1. 1. 1,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,1,Damaging,"34,04","21,91"
"low bq, low freq, many artifacts, many samples",UPN2_057,17,7578436,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln165Leu/c.494A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),14124,146,14356,"0,0101699638",0,0,0,0,1,0,0,0,1,NO,NO,COSM44850,haematopoietic_and_lymphoid_tissue. salivary_gland. soft_tissue,1. 1. 1,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,1,Damaging,"34,09","20,62"
"low bq, low freq, many artifacts, many samples",UPN2_058,17,7578436,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln165Leu/c.494A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),12562,142,12755,"0,0111328891",0,0,0,0,1,0,0,0,1,NO,NO,COSM44850,haematopoietic_and_lymphoid_tissue. salivary_gland. soft_tissue,1. 1. 1,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,1,Damaging,"34,1","18,58"
"low bq, low freq, many artifacts",UPN2_013,17,7578436,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln165Leu/c.494A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),2663,30,2701,"0,0111069974",0,0,0,0,1,0,0,0,1,NO,NO,COSM44850,haematopoietic_and_lymphoid_tissue. salivary_gland. soft_tissue,1. 1. 1,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,1,Damaging,"34,36","20,33"
"low bq, low freq, many artifacts, many samples",UPN2_032,17,7578439,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys164Met/c.491A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),3008,32,3049,"0,0104952443",0,0,0,0,1,0,0,0,1,NO,NO,COSM44841,breast. large_intestine. stomach,1. 2. 1,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,61,Tolerated,"34,19","17,66"
"low bq, low freq, many artifacts, many samples",UPN2_050,17,7578439,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys164Met/c.491A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),10504,112,10669,"0,0104977036",0,0,0,0,1,0,0,0,1,NO,NO,COSM44841,breast. large_intestine. stomach,1. 2. 1,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,61,Tolerated,"33,07","18,21"
"low bq, low freq, many artifacts, many samples",UPN2_058,17,7578439,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys164Met/c.491A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),12564,129,12755,"0,0101136809",0,0,0,0,1,0,0,0,1,NO,NO,COSM44841,breast. large_intestine. stomach,1. 2. 1,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,61,Tolerated,"33,25","16,74"
"low bq, low freq, many artifacts, many samples",UPN2_001,17,7578440,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys164*/c.490A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),3445,35,3494,"0,0100171723",0,0,0,0,1,0,0,0,1,NO,NO,COSM380904. COSM10750. COSM380905,lung. central_nervous_system. liver. oesophagus. upper_aerodigestive_tract. urinary_tract,5. 1. 1. 2. 2. 2,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,79","17,77"
"low bq, low freq, many artifacts, many samples",UPN2_041,17,7578440,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys164*/c.490A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),17335,253,17691,"0,014301057",0,0,0,0,1,0,0,0,1,NO,NO,COSM380904. COSM10750. COSM380905,lung. central_nervous_system. liver. oesophagus. upper_aerodigestive_tract. urinary_tract,5. 1. 1. 2. 2. 2,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,35","18,98"
"low bq, low freq, many artifacts, many samples",UPN2_004,17,7578440,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys164*/c.490A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),2311,24,2341,"0,010252029",0,0,0,0,1,0,0,0,1,NO,NO,COSM380904. COSM10750. COSM380905,lung. central_nervous_system. liver. oesophagus. upper_aerodigestive_tract. urinary_tract,5. 1. 1. 2. 2. 2,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,91","20,04"
"low bq, low freq, many artifacts, many samples",UPN2_042,17,7578440,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys164*/c.490A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),13297,172,13567,"0,0126778212",0,0,0,0,1,0,0,0,1,NO,NO,COSM380904. COSM10750. COSM380905,lung. central_nervous_system. liver. oesophagus. upper_aerodigestive_tract. urinary_tract,5. 1. 1. 2. 2. 2,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,28","17,9"
"low bq, low freq, many artifacts, many samples",UPN2_043,17,7578440,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys164*/c.490A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),6652,94,6772,"0,0138806852",0,0,0,0,1,0,0,0,1,NO,NO,COSM380904. COSM10750. COSM380905,lung. central_nervous_system. liver. oesophagus. upper_aerodigestive_tract. urinary_tract,5. 1. 1. 2. 2. 2,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,37","19,27"
"low bq, low freq, many artifacts, many samples",UPN2_044,17,7578440,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys164*/c.490A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),4817,63,4941,"0,0127504554",0,0,0,0,1,0,0,0,1,NO,NO,COSM380904. COSM10750. COSM380905,lung. central_nervous_system. liver. oesophagus. upper_aerodigestive_tract. urinary_tract,5. 1. 1. 2. 2. 2,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,27",17
"low bq, low freq, many artifacts, many samples",UPN2_045,17,7578440,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys164*/c.490A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),6795,99,6936,"0,0142733564",0,0,0,0,1,0,0,0,1,NO,NO,COSM380904. COSM10750. COSM380905,lung. central_nervous_system. liver. oesophagus. upper_aerodigestive_tract. urinary_tract,5. 1. 1. 2. 2. 2,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,4","19,27"
"low bq, low freq, many artifacts, many samples",UPN2_032,17,7578440,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys164*/c.490A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),2992,39,3049,"0,012791079",0,0,0,0,1,0,0,0,1,NO,NO,COSM380904. COSM10750. COSM380905,lung. central_nervous_system. liver. oesophagus. upper_aerodigestive_tract. urinary_tract,5. 1. 1. 2. 2. 2,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,21","21,56"
"low bq, low freq, many artifacts, many samples",UPN2_046,17,7578440,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys164*/c.490A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),12942,168,13182,"0,0127446518",0,0,0,0,1,0,0,0,1,NO,NO,COSM380904. COSM10750. COSM380905,lung. central_nervous_system. liver. oesophagus. upper_aerodigestive_tract. urinary_tract,5. 1. 1. 2. 2. 2,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,26","18,15"
"low bq, low freq, many artifacts, many samples",UPN2_047,17,7578440,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys164*/c.490A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),14925,191,15218,"0,0125509265",0,0,0,0,1,0,0,0,1,NO,NO,COSM380904. COSM10750. COSM380905,lung. central_nervous_system. liver. oesophagus. upper_aerodigestive_tract. urinary_tract,5. 1. 1. 2. 2. 2,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,37","17,35"
"low bq, low freq, many artifacts, many samples",UPN2_048,17,7578440,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys164*/c.490A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),15340,192,15638,"0,0122777849",0,0,0,0,1,0,0,0,1,NO,NO,COSM380904. COSM10750. COSM380905,lung. central_nervous_system. liver. oesophagus. upper_aerodigestive_tract. urinary_tract,5. 1. 1. 2. 2. 2,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,36","17,34"
"low bq, low freq, many artifacts, many samples",UPN2_049,17,7578440,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys164*/c.490A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),19901,253,20282,"0,012474115",0,0,0,0,1,0,0,0,1,NO,NO,COSM380904. COSM10750. COSM380905,lung. central_nervous_system. liver. oesophagus. upper_aerodigestive_tract. urinary_tract,5. 1. 1. 2. 2. 2,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,24","18,27"
"low bq, low freq, many artifacts, many samples",UPN2_050,17,7578440,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys164*/c.490A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),10462,131,10669,"0,0122785641",0,0,0,0,1,0,0,0,1,NO,NO,COSM380904. COSM10750. COSM380905,lung. central_nervous_system. liver. oesophagus. upper_aerodigestive_tract. urinary_tract,5. 1. 1. 2. 2. 2,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,28","18,81"
"low bq, low freq, many artifacts, many samples",UPN2_051,17,7578440,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys164*/c.490A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),11945,163,12178,"0,0133847922",0,0,0,0,1,0,0,0,1,NO,NO,COSM380904. COSM10750. COSM380905,lung. central_nervous_system. liver. oesophagus. upper_aerodigestive_tract. urinary_tract,5. 1. 1. 2. 2. 2,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,44","18,1"
"low bq, low freq, many artifacts, many samples",UPN2_052,17,7578440,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys164*/c.490A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),6043,79,6166,"0,0128121959",0,0,0,0,1,0,0,0,1,NO,NO,COSM380904. COSM10750. COSM380905,lung. central_nervous_system. liver. oesophagus. upper_aerodigestive_tract. urinary_tract,5. 1. 1. 2. 2. 2,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,41","18,37"
"low bq, low freq, many artifacts, many samples",UPN2_053,17,7578440,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys164*/c.490A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),15765,195,16086,"0,0121223424",0,0,0,0,1,0,0,0,1,NO,NO,COSM380904. COSM10750. COSM380905,lung. central_nervous_system. liver. oesophagus. upper_aerodigestive_tract. urinary_tract,5. 1. 1. 2. 2. 2,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,28","18,24"
"low bq, low freq, many artifacts, many samples",UPN2_054,17,7578440,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys164*/c.490A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),8713,121,8915,"0,0135726304",0,0,0,0,1,0,0,0,1,NO,NO,COSM380904. COSM10750. COSM380905,lung. central_nervous_system. liver. oesophagus. upper_aerodigestive_tract. urinary_tract,5. 1. 1. 2. 2. 2,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,28","18,34"
"low bq, low freq, many artifacts, many samples",UPN2_011,17,7578440,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys164*/c.490A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),8421,88,8537,"0,0103080708",0,0,0,0,1,0,0,0,1,NO,NO,COSM380904. COSM10750. COSM380905,lung. central_nervous_system. liver. oesophagus. upper_aerodigestive_tract. urinary_tract,5. 1. 1. 2. 2. 2,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,9","18,42"
"low bq, low freq, many artifacts, many samples",UPN2_055,17,7578440,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys164*/c.490A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),12718,148,12946,"0,0114321026",0,0,0,0,1,0,0,0,1,NO,NO,COSM380904. COSM10750. COSM380905,lung. central_nervous_system. liver. oesophagus. upper_aerodigestive_tract. urinary_tract,5. 1. 1. 2. 2. 2,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,28","18,99"
"low bq, low freq, many artifacts, many samples",UPN2_056,17,7578440,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys164*/c.490A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),9683,130,9877,"0,0131618913",0,0,0,0,1,0,0,0,1,NO,NO,COSM380904. COSM10750. COSM380905,lung. central_nervous_system. liver. oesophagus. upper_aerodigestive_tract. urinary_tract,5. 1. 1. 2. 2. 2,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,47","18,85"
"low bq, low freq, many artifacts, many samples",UPN2_057,17,7578440,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys164*/c.490A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),14075,208,14353,"0,0144917439",0,0,0,0,1,0,0,0,1,NO,NO,COSM380904. COSM10750. COSM380905,lung. central_nervous_system. liver. oesophagus. upper_aerodigestive_tract. urinary_tract,5. 1. 1. 2. 2. 2,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,29","18,9"
"low bq, low freq, many artifacts, many samples",UPN2_058,17,7578440,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys164*/c.490A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),12538,154,12753,"0,0120755901",0,0,0,0,1,0,0,0,1,NO,NO,COSM380904. COSM10750. COSM380905,lung. central_nervous_system. liver. oesophagus. upper_aerodigestive_tract. urinary_tract,5. 1. 1. 2. 2. 2,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,34","18,44"
"low bq, low freq, many artifacts, many samples",UPN2_012,17,7578440,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys164*/c.490A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),4398,47,4462,"0,0105333931",0,0,0,0,1,0,0,0,1,NO,NO,COSM380904. COSM10750. COSM380905,lung. central_nervous_system. liver. oesophagus. upper_aerodigestive_tract. urinary_tract,5. 1. 1. 2. 2. 2,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,75","19,17"
"low bq, low freq, many artifacts, many samples",UPN2_065,17,7578440,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys164*/c.490A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),3526,36,3580,"0,0100558659",0,0,0,0,1,0,0,0,1,NO,NO,COSM380904. COSM10750. COSM380905,lung. central_nervous_system. liver. oesophagus. upper_aerodigestive_tract. urinary_tract,5. 1. 1. 2. 2. 2,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,68","17,33"
"low bq, low freq, many artifacts",UPN2_086,17,7578440,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys164*/c.490A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),2004,22,2031,"0,0108321024",0,0,0,0,1,0,0,0,1,NO,NO,COSM380904. COSM10750. COSM380905,lung. central_nervous_system. liver. oesophagus. upper_aerodigestive_tract. urinary_tract,5. 1. 1. 2. 2. 2,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,79","18,64"
"low freq, many artifacts",UPN2_044,17,7578440,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys164Glu/c.490A>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),4817,54,4941,"0,0109289617",0,0,0,0,0,0,0,1,1,NO,NO,COSM10762. COSM707872. COSM2153638. COSM707873. COSM3820721,breast. central_nervous_system. haematopoietic_and_lymphoid_tissue. large_intestine. liver. lung. ovary. urinary_tract,1. 9. 5. 3. 1. 5. 7. 2,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,1,Damaging,"33,27","34,98"
"low freq, many artifacts, many samples",UPN2_006,17,7578446,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile162Phe/c.484A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),4847,59,4926,"0,0119772635",0,0,0,0,1,0,0,0,1,NO,NO,COSM4070049. COSM4070052. COSM4070050. COSM4070051. COSM44320,breast. stomach. central_nervous_system. liver. lung. prostate. soft_tissue. urinary_tract,5. 5. 1. 2. 2. 1. 1. 3,NO,NO,NO,NO,NO,NO,"-3,83",Deleterious,1,Damaging,"34,49","27,85"
"low bq, low freq, many artifacts, many samples",UPN2_050,17,7578446,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile162Phe/c.484A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),10521,111,10667,"0,0104059248",0,0,0,0,1,0,0,0,1,NO,NO,COSM4070049. COSM4070052. COSM4070050. COSM4070051. COSM44320,breast. stomach. central_nervous_system. liver. lung. prostate. soft_tissue. urinary_tract,5. 5. 1. 2. 2. 1. 1. 3,NO,NO,NO,NO,NO,NO,"-3,83",Deleterious,1,Damaging,"33,97","21,57"
"low bq, low freq, many artifacts, many samples",UPN2_058,17,7578446,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile162Phe/c.484A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),12572,132,12750,"0,0103529412",0,0,0,0,1,0,0,0,1,NO,NO,COSM4070049. COSM4070052. COSM4070050. COSM4070051. COSM44320,breast. stomach. central_nervous_system. liver. lung. prostate. soft_tissue. urinary_tract,5. 5. 1. 2. 2. 1. 1. 3,NO,NO,NO,NO,NO,NO,"-3,83",Deleterious,1,Damaging,"33,94","22,59"
"low bq, low freq, many artifacts, many samples",UPN2_001,17,7578452,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met160Leu/c.478A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),3441,40,3493,"0,0114514744",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,rs377274728,NO,NO,NO,NO,"-1,43",Neutral,88,Tolerated,"34,29","18,08"
"low bq, low freq, many artifacts, many samples",UPN2_041,17,7578452,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met160Leu/c.478A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),17430,187,17684,"0,0105745306",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,rs377274728,NO,NO,NO,NO,"-1,43",Neutral,88,Tolerated,"33,56","18,74"
"low bq, low freq, many artifacts, many samples",UPN2_042,17,7578452,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met160Leu/c.478A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),13359,162,13566,"0,0119416188",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,rs377274728,NO,NO,NO,NO,"-1,43",Neutral,88,Tolerated,"33,67","19,04"
"low bq, low freq, many artifacts, many samples",UPN2_032,17,7578452,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met160Leu/c.478A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),2994,35,3049,"0,0114791735",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,rs377274728,NO,NO,NO,NO,"-1,43",Neutral,88,Tolerated,"34,51","20,66"
"low bq, low freq, many artifacts, many samples",UPN2_046,17,7578452,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met160Leu/c.478A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),12967,147,13177,"0,0111558018",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,rs377274728,NO,NO,NO,NO,"-1,43",Neutral,88,Tolerated,"33,72","18,65"
"low bq, low freq, many artifacts, many samples",UPN2_047,17,7578452,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met160Leu/c.478A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),14993,169,15211,"0,0111103806",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,rs377274728,NO,NO,NO,NO,"-1,43",Neutral,88,Tolerated,"33,62","20,09"
"low bq, low freq, many artifacts, many samples",UPN2_049,17,7578452,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met160Leu/c.478A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),19915,260,20275,"0,0128236745",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,rs377274728,NO,NO,NO,NO,"-1,43",Neutral,88,Tolerated,"33,69","20,06"
"low bq, low freq, many artifacts, many samples",UPN2_050,17,7578452,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met160Leu/c.478A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),10477,133,10665,"0,0124706985",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,rs377274728,NO,NO,NO,NO,"-1,43",Neutral,88,Tolerated,"33,68","19,6"
"low bq, low freq, many artifacts, many samples",UPN2_051,17,7578452,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met160Leu/c.478A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),12002,124,12175,"0,0101848049",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,rs377274728,NO,NO,NO,NO,"-1,43",Neutral,88,Tolerated,"33,73","18,07"
"low bq, low freq, many artifacts, many samples",UPN2_052,17,7578452,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met160Leu/c.478A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),6077,62,6163,"0,0100600357",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,rs377274728,NO,NO,NO,NO,"-1,43",Neutral,88,Tolerated,"33,77","17,13"
"low bq, low freq, many artifacts, many samples",UPN2_053,17,7578452,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met160Leu/c.478A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),15851,163,16080,"0,0101368159",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,rs377274728,NO,NO,NO,NO,"-1,43",Neutral,88,Tolerated,"33,8","19,35"
"low bq, low freq, many artifacts, many samples",UPN2_054,17,7578452,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met160Leu/c.478A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),8779,93,8911,"0,0104365391",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,rs377274728,NO,NO,NO,NO,"-1,43",Neutral,88,Tolerated,"33,67","21,2"
"low bq, low freq, many artifacts, many samples",UPN2_055,17,7578452,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met160Leu/c.478A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),12759,135,12942,"0,0104311544",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,rs377274728,NO,NO,NO,NO,"-1,43",Neutral,88,Tolerated,"33,69","19,35"
"low bq, low freq, many artifacts, many samples",UPN2_056,17,7578452,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met160Leu/c.478A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),9719,111,9875,"0,0112405063",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,rs377274728,NO,NO,NO,NO,"-1,43",Neutral,88,Tolerated,"33,75","18,75"
"low bq, low freq, many artifacts, many samples",UPN2_057,17,7578452,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met160Leu/c.478A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),14134,165,14343,"0,0115038695",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,rs377274728,NO,NO,NO,NO,"-1,43",Neutral,88,Tolerated,"33,56","19,41"
"low bq, low freq, many artifacts",UPN2_058,17,7578452,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met160Leu/c.478A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),12581,131,12750,"0,0102745098",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,rs377274728,NO,NO,NO,NO,"-1,43",Neutral,88,Tolerated,"33,62","17,99"
inspected,UPN2_098,17,7578452,TGGCGCG,T,inframe_deletion(MODERATE||cgcgcc/|p.Arg158_Ala159del/c.472_477delCGCGCC|393|TP53|protein_coding|CODING|ENST00000269305|5|T),5076,111,5210,"0,0213051823",0,0,0,1,1,0,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-14,99",Deleterious,NA,NA,"33,53",NA
"low bq, low freq, many artifacts, many samples",UPN2_044,17,7578460,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val157Gly/c.470T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),4865,50,4937,"0,0101276079",0,0,0,0,1,0,0,0,1,NO,NO,COSM3403269. COSM43903. COSM3403270. COSM1480074. COSM1480073,central_nervous_system. liver. breast. haematopoietic_and_lymphoid_tissue. lung. ovary. stomach,7. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,09",Deleterious,0,Damaging,"29,04",14
"low bq, low freq, many artifacts, many samples",UPN2_045,17,7578460,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val157Gly/c.470T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),6833,75,6933,"0,0108178278",0,0,0,0,1,0,0,0,1,NO,NO,COSM3403269. COSM43903. COSM3403270. COSM1480074. COSM1480073,central_nervous_system. liver. breast. haematopoietic_and_lymphoid_tissue. lung. ovary. stomach,7. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,09",Deleterious,0,Damaging,"28,68","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_059,17,7578460,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val157Gly/c.470T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),4466,98,4577,"0,0214114049",0,0,0,0,1,0,0,0,1,NO,NO,COSM3403269. COSM43903. COSM3403270. COSM1480074. COSM1480073,central_nervous_system. liver. breast. haematopoietic_and_lymphoid_tissue. lung. ovary. stomach,7. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,09",Deleterious,0,Damaging,"27,15","14,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_060,17,7578460,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val157Gly/c.470T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),4907,105,5028,"0,0208830549",0,0,0,0,1,0,0,0,1,NO,NO,COSM3403269. COSM43903. COSM3403270. COSM1480074. COSM1480073,central_nervous_system. liver. breast. haematopoietic_and_lymphoid_tissue. lung. ovary. stomach,7. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,09",Deleterious,0,Damaging,"26,98","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_092,17,7578460,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val157Gly/c.470T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),3115,33,3158,"0,0104496517",0,0,0,0,1,0,0,0,1,NO,NO,COSM3403269. COSM43903. COSM3403270. COSM1480074. COSM1480073,central_nervous_system. liver. breast. haematopoietic_and_lymphoid_tissue. lung. ovary. stomach,7. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,09",Deleterious,0,Damaging,"29,92","14,21"
"low bq, bad alignment, many samples",UPN2_061,17,7578460,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val157Gly/c.470T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),4968,116,5099,"0,0227495587",0,0,0,0,1,0,0,0,1,NO,NO,COSM3403269. COSM43903. COSM3403270. COSM1480074. COSM1480073,central_nervous_system. liver. breast. haematopoietic_and_lymphoid_tissue. lung. ovary. stomach,7. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,09",Deleterious,0,Damaging,"26,87","14,22"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,17,7578460,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val157Gly/c.470T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),5374,102,5494,"0,018565708",0,0,0,0,1,0,0,0,1,NO,NO,COSM3403269. COSM43903. COSM3403270. COSM1480074. COSM1480073,central_nervous_system. liver. breast. haematopoietic_and_lymphoid_tissue. lung. ovary. stomach,7. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,09",Deleterious,0,Damaging,"26,8","15,48"
"low bq, bad alignment, many samples",UPN2_063,17,7578460,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val157Gly/c.470T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),5767,132,5928,"0,0222672065",0,0,0,0,1,0,0,0,1,NO,NO,COSM3403269. COSM43903. COSM3403270. COSM1480074. COSM1480073,central_nervous_system. liver. breast. haematopoietic_and_lymphoid_tissue. lung. ovary. stomach,7. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,09",Deleterious,0,Damaging,"26,69","14,2"
"low bq, many samples",UPN2_064,17,7578460,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val157Gly/c.470T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),5925,154,6096,"0,0252624672",0,0,0,0,1,0,0,0,1,NO,NO,COSM3403269. COSM43903. COSM3403270. COSM1480074. COSM1480073,central_nervous_system. liver. breast. haematopoietic_and_lymphoid_tissue. lung. ovary. stomach,7. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,09",Deleterious,0,Damaging,"27,02","14,93"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_065,17,7578460,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val157Gly/c.470T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),3505,63,3578,"0,017607602",0,0,0,0,1,0,0,0,1,NO,NO,COSM3403269. COSM43903. COSM3403270. COSM1480074. COSM1480073,central_nervous_system. liver. breast. haematopoietic_and_lymphoid_tissue. lung. ovary. stomach,7. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,09",Deleterious,0,Damaging,"26,74","14,71"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_066,17,7578460,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val157Gly/c.470T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),3218,67,3299,"0,0203091846",0,0,0,0,1,0,0,0,1,NO,NO,COSM3403269. COSM43903. COSM3403270. COSM1480074. COSM1480073,central_nervous_system. liver. breast. haematopoietic_and_lymphoid_tissue. lung. ovary. stomach,7. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,09",Deleterious,0,Damaging,"26,85","14,3"
"low bq, many samples",UPN2_067,17,7578460,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val157Gly/c.470T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),3593,85,3688,"0,0230477223",0,0,0,0,1,0,0,0,1,NO,NO,COSM3403269. COSM43903. COSM3403270. COSM1480074. COSM1480073,central_nervous_system. liver. breast. haematopoietic_and_lymphoid_tissue. lung. ovary. stomach,7. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,09",Deleterious,0,Damaging,"27,02","14,67"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_068,17,7578460,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val157Gly/c.470T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),3908,87,4002,"0,0217391304",0,0,0,0,1,0,0,0,1,NO,NO,COSM3403269. COSM43903. COSM3403270. COSM1480074. COSM1480073,central_nervous_system. liver. breast. haematopoietic_and_lymphoid_tissue. lung. ovary. stomach,7. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,09",Deleterious,0,Damaging,"26,93","14,71"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_069,17,7578460,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val157Gly/c.470T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),5275,107,5397,"0,0198258292",0,0,0,0,1,0,0,0,1,NO,NO,COSM3403269. COSM43903. COSM3403270. COSM1480074. COSM1480073,central_nervous_system. liver. breast. haematopoietic_and_lymphoid_tissue. lung. ovary. stomach,7. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,09",Deleterious,0,Damaging,"26,99","14,49"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_070,17,7578460,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val157Gly/c.470T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),3313,70,3392,"0,0206367925",0,0,0,0,1,0,0,0,1,NO,NO,COSM3403269. COSM43903. COSM3403270. COSM1480074. COSM1480073,central_nervous_system. liver. breast. haematopoietic_and_lymphoid_tissue. lung. ovary. stomach,7. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,09",Deleterious,0,Damaging,"26,6","14,1"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,17,7578460,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val157Gly/c.470T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),4563,95,4673,"0,0203295527",0,0,0,0,1,0,0,0,1,NO,NO,COSM3403269. COSM43903. COSM3403270. COSM1480074. COSM1480073,central_nervous_system. liver. breast. haematopoietic_and_lymphoid_tissue. lung. ovary. stomach,7. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,09",Deleterious,0,Damaging,"26,83","15,28"
"low freq, many artifacts, many samples",UPN2_072,17,7578460,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val157Gly/c.470T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),5946,127,6097,"0,0208299164",0,0,0,0,1,0,0,0,1,NO,NO,COSM3403269. COSM43903. COSM3403270. COSM1480074. COSM1480073,central_nervous_system. liver. breast. haematopoietic_and_lymphoid_tissue. lung. ovary. stomach,7. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,09",Deleterious,0,Damaging,27,"15,34"
"low bq, bad alignment, many samples",UPN2_073,17,7578460,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val157Gly/c.470T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),3716,87,3811,"0,0228286539",0,0,0,0,1,0,0,0,1,NO,NO,COSM3403269. COSM43903. COSM3403270. COSM1480074. COSM1480073,central_nervous_system. liver. breast. haematopoietic_and_lymphoid_tissue. lung. ovary. stomach,7. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,09",Deleterious,0,Damaging,"26,95","14,4"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,17,7578460,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val157Gly/c.470T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),2357,35,2401,"0,0145772595",0,0,0,0,1,0,0,0,1,NO,NO,COSM3403269. COSM43903. COSM3403270. COSM1480074. COSM1480073,central_nervous_system. liver. breast. haematopoietic_and_lymphoid_tissue. lung. ovary. stomach,7. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,09",Deleterious,0,Damaging,"26,2","14,2"
"low bq, many samples",UPN2_075,17,7578460,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val157Gly/c.470T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),6161,152,6334,"0,023997474",0,0,0,0,1,0,0,0,1,NO,NO,COSM3403269. COSM43903. COSM3403270. COSM1480074. COSM1480073,central_nervous_system. liver. breast. haematopoietic_and_lymphoid_tissue. lung. ovary. stomach,7. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,09",Deleterious,0,Damaging,"27,02","14,51"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,17,7578460,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val157Gly/c.470T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),3931,83,4017,"0,0206621857",0,0,0,0,1,0,0,0,1,NO,NO,COSM3403269. COSM43903. COSM3403270. COSM1480074. COSM1480073,central_nervous_system. liver. breast. haematopoietic_and_lymphoid_tissue. lung. ovary. stomach,7. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,09",Deleterious,0,Damaging,"26,87","14,76"
"low bq, bad alignment, many samples",UPN2_077,17,7578460,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val157Gly/c.470T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),3438,85,3538,"0,0240248728",0,0,0,0,1,0,0,0,1,NO,NO,COSM3403269. COSM43903. COSM3403270. COSM1480074. COSM1480073,central_nervous_system. liver. breast. haematopoietic_and_lymphoid_tissue. lung. ovary. stomach,7. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,09",Deleterious,0,Damaging,"26,93","14,72"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,17,7578460,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val157Gly/c.470T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),4685,102,4805,"0,0212278876",0,0,0,0,1,0,0,0,1,NO,NO,COSM3403269. COSM43903. COSM3403270. COSM1480074. COSM1480073,central_nervous_system. liver. breast. haematopoietic_and_lymphoid_tissue. lung. ovary. stomach,7. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,09",Deleterious,0,Damaging,"26,69","14,39"
"low bq, bad alignment, many samples",UPN2_079,17,7578460,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val157Gly/c.470T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),2877,71,2954,"0,0240352065",0,0,0,0,1,0,0,0,1,NO,NO,COSM3403269. COSM43903. COSM3403270. COSM1480074. COSM1480073,central_nervous_system. liver. breast. haematopoietic_and_lymphoid_tissue. lung. ovary. stomach,7. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,09",Deleterious,0,Damaging,"26,82","15,04"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,17,7578460,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val157Gly/c.470T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),4800,108,4927,"0,0219200325",0,0,0,0,1,0,0,0,1,NO,NO,COSM3403269. COSM43903. COSM3403270. COSM1480074. COSM1480073,central_nervous_system. liver. breast. haematopoietic_and_lymphoid_tissue. lung. ovary. stomach,7. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,09",Deleterious,0,Damaging,"26,98","14,66"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_081,17,7578460,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val157Gly/c.470T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),6916,125,7058,"0,0177103995",0,0,0,0,1,0,0,0,1,NO,NO,COSM3403269. COSM43903. COSM3403270. COSM1480074. COSM1480073,central_nervous_system. liver. breast. haematopoietic_and_lymphoid_tissue. lung. ovary. stomach,7. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,09",Deleterious,0,Damaging,"26,9","14,58"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_082,17,7578460,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val157Gly/c.470T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),4339,89,4435,"0,0200676437",0,0,0,0,1,0,0,0,1,NO,NO,COSM3403269. COSM43903. COSM3403270. COSM1480074. COSM1480073,central_nervous_system. liver. breast. haematopoietic_and_lymphoid_tissue. lung. ovary. stomach,7. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,09",Deleterious,0,Damaging,"26,99","14,87"
"low bq, bad alignment, many samples",UPN2_083,17,7578460,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val157Gly/c.470T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),5370,133,5521,"0,0240898388",0,0,0,0,1,0,0,0,1,NO,NO,COSM3403269. COSM43903. COSM3403270. COSM1480074. COSM1480073,central_nervous_system. liver. breast. haematopoietic_and_lymphoid_tissue. lung. ovary. stomach,7. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,09",Deleterious,0,Damaging,"26,72","14,21"
"low bq, bad alignment, many samples",UPN2_084,17,7578460,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val157Gly/c.470T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),5218,123,5354,"0,0229734778",0,0,0,0,1,0,0,0,1,NO,NO,COSM3403269. COSM43903. COSM3403270. COSM1480074. COSM1480073,central_nervous_system. liver. breast. haematopoietic_and_lymphoid_tissue. lung. ovary. stomach,7. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,09",Deleterious,0,Damaging,"26,89","14,53"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_085,17,7578460,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val157Gly/c.470T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),2854,62,2925,"0,0211965812",0,0,0,0,1,0,0,0,1,NO,NO,COSM3403269. COSM43903. COSM3403270. COSM1480074. COSM1480073,central_nervous_system. liver. breast. haematopoietic_and_lymphoid_tissue. lung. ovary. stomach,7. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,09",Deleterious,0,Damaging,"26,79","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_086,17,7578460,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val157Gly/c.470T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),1985,40,2031,"0,0196947317",0,0,0,0,1,0,0,0,1,NO,NO,COSM3403269. COSM43903. COSM3403270. COSM1480074. COSM1480073,central_nervous_system. liver. breast. haematopoietic_and_lymphoid_tissue. lung. ovary. stomach,7. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,09",Deleterious,0,Damaging,"27,13","14,5"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_087,17,7578460,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val157Gly/c.470T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),4860,103,4979,"0,0206868849",0,0,0,0,1,0,0,0,1,NO,NO,COSM3403269. COSM43903. COSM3403270. COSM1480074. COSM1480073,central_nervous_system. liver. breast. haematopoietic_and_lymphoid_tissue. lung. ovary. stomach,7. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,09",Deleterious,0,Damaging,"26,99","15,04"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_088,17,7578460,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val157Gly/c.470T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),3429,67,3515,"0,0190611664",0,0,0,0,1,0,0,0,1,NO,NO,COSM3403269. COSM43903. COSM3403270. COSM1480074. COSM1480073,central_nervous_system. liver. breast. haematopoietic_and_lymphoid_tissue. lung. ovary. stomach,7. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,09",Deleterious,0,Damaging,"26,93","15,27"
"low bq, low freq, many artifacts",UPN2_102,17,7578460,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val157Gly/c.470T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),4783,49,4841,"0,0101218756",0,0,0,0,1,0,0,0,1,NO,NO,COSM3403269. COSM43903. COSM3403270. COSM1480074. COSM1480073,central_nervous_system. liver. breast. haematopoietic_and_lymphoid_tissue. lung. ovary. stomach,7. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,09",Deleterious,0,Damaging,"29,62","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_041,17,7578467,T,A,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr155Ser/c.463A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),17374,199,17686,"0,0112518376",0,0,0,0,1,0,0,0,1,NO,NO,COSM44815,soft_tissue,1,NO,NO,NO,NO,NO,NO,"0,54",Neutral,"0,76",Tolerated,"33,21","16,75"
"low bq, low freq, many artifacts, many samples",UPN2_042,17,7578467,T,A,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr155Ser/c.463A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),13346,143,13563,"0,0105433901",0,0,0,0,1,0,0,0,1,NO,NO,COSM44815,soft_tissue,1,NO,NO,NO,NO,NO,NO,"0,54",Neutral,"0,76",Tolerated,"33,29","18,43"
"low bq, low freq, many artifacts, many samples",UPN2_043,17,7578467,T,A,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr155Ser/c.463A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),6643,86,6767,"0,0127087336",0,0,0,0,1,0,0,0,1,NO,NO,COSM44815,soft_tissue,1,NO,NO,NO,NO,NO,NO,"0,54",Neutral,"0,76",Tolerated,"33,28","18,06"
"low bq, low freq, many artifacts, many samples",UPN2_044,17,7578467,T,A,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr155Ser/c.463A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),4846,69,4935,"0,0139817629",0,0,0,0,1,0,0,0,1,NO,NO,COSM44815,soft_tissue,1,NO,NO,NO,NO,NO,NO,"0,54",Neutral,"0,76",Tolerated,"33,21","19,49"
"low bq, low freq, many artifacts, many samples",UPN2_045,17,7578467,T,A,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr155Ser/c.463A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),6833,78,6947,"0,0112278681",0,0,0,0,1,0,0,0,1,NO,NO,COSM44815,soft_tissue,1,NO,NO,NO,NO,NO,NO,"0,54",Neutral,"0,76",Tolerated,"33,29","19,04"
"low bq, low freq, many artifacts, many samples",UPN2_046,17,7578467,T,A,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr155Ser/c.463A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),12973,157,13183,"0,0119092771",0,0,0,0,1,0,0,0,1,NO,NO,COSM44815,soft_tissue,1,NO,NO,NO,NO,NO,NO,"0,54",Neutral,"0,76",Tolerated,"33,21","18,02"
"low bq, low freq, many artifacts, many samples",UPN2_047,17,7578467,T,A,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr155Ser/c.463A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),14952,188,15221,"0,0123513567",0,0,0,0,1,0,0,0,1,NO,NO,COSM44815,soft_tissue,1,NO,NO,NO,NO,NO,NO,"0,54",Neutral,"0,76",Tolerated,"33,28","18,31"
"low bq, low freq, many artifacts, many samples",UPN2_048,17,7578467,T,A,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr155Ser/c.463A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),15415,162,15645,"0,0103547459",0,0,0,0,1,0,0,0,1,NO,NO,COSM44815,soft_tissue,1,NO,NO,NO,NO,NO,NO,"0,54",Neutral,"0,76",Tolerated,"33,3","16,82"
"low bq, low freq, many artifacts, many samples",UPN2_049,17,7578467,T,A,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr155Ser/c.463A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),19927,257,20281,"0,012671959",0,0,0,0,1,0,0,0,1,NO,NO,COSM44815,soft_tissue,1,NO,NO,NO,NO,NO,NO,"0,54",Neutral,"0,76",Tolerated,"33,23","17,93"
"low bq, low freq, many artifacts, many samples",UPN2_050,17,7578467,T,A,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr155Ser/c.463A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),10472,122,10656,"0,0114489489",0,0,0,0,1,0,0,0,1,NO,NO,COSM44815,soft_tissue,1,NO,NO,NO,NO,NO,NO,"0,54",Neutral,"0,76",Tolerated,"33,15","16,54"
"low bq, low freq, many artifacts, many samples",UPN2_051,17,7578467,T,A,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr155Ser/c.463A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),11958,140,12175,"0,0114989733",0,0,0,0,1,0,0,0,1,NO,NO,COSM44815,soft_tissue,1,NO,NO,NO,NO,NO,NO,"0,54",Neutral,"0,76",Tolerated,"33,39","17,26"
"low bq, low freq, many artifacts, many samples",UPN2_052,17,7578467,T,A,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr155Ser/c.463A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),6061,63,6156,"0,0102339181",0,0,0,0,1,0,0,0,1,NO,NO,COSM44815,soft_tissue,1,NO,NO,NO,NO,NO,NO,"0,54",Neutral,"0,76",Tolerated,"33,18","16,24"
"low bq, low freq, many artifacts, many samples",UPN2_053,17,7578467,T,A,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr155Ser/c.463A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),15822,198,16108,"0,0122920288",0,0,0,0,1,0,0,0,1,NO,NO,COSM44815,soft_tissue,1,NO,NO,NO,NO,NO,NO,"0,54",Neutral,"0,76",Tolerated,"33,22","17,53"
"low bq, low freq, many artifacts, many samples",UPN2_054,17,7578467,T,A,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr155Ser/c.463A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),8767,101,8929,"0,0113114571",0,0,0,0,1,0,0,0,1,NO,NO,COSM44815,soft_tissue,1,NO,NO,NO,NO,NO,NO,"0,54",Neutral,"0,76",Tolerated,"33,28","16,36"
"low bq, low freq, many artifacts, many samples",UPN2_055,17,7578467,T,A,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr155Ser/c.463A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),12727,151,12946,"0,0116638344",0,0,0,0,1,0,0,0,1,NO,NO,COSM44815,soft_tissue,1,NO,NO,NO,NO,NO,NO,"0,54",Neutral,"0,76",Tolerated,"33,23","19,77"
"low bq, low freq, many artifacts, many samples",UPN2_056,17,7578467,T,A,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr155Ser/c.463A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),9718,105,9879,"0,0106286061",0,0,0,0,1,0,0,0,1,NO,NO,COSM44815,soft_tissue,1,NO,NO,NO,NO,NO,NO,"0,54",Neutral,"0,76",Tolerated,"33,42","16,77"
"low bq, low freq, many artifacts, many samples",UPN2_057,17,7578467,T,A,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr155Ser/c.463A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),14097,163,14349,"0,0113596766",0,0,0,0,1,0,0,0,1,NO,NO,COSM44815,soft_tissue,1,NO,NO,NO,NO,NO,NO,"0,54",Neutral,"0,76",Tolerated,"33,26","17,64"
"low bq, low freq, many artifacts",UPN2_058,17,7578467,T,A,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr155Ser/c.463A>T|393|TP53|protein_coding|CODING|ENST00000269305|5|A),12521,171,12749,"0,0134128167",0,0,0,0,1,0,0,0,1,NO,NO,COSM44815,soft_tissue,1,NO,NO,NO,NO,NO,NO,"0,54",Neutral,"0,76",Tolerated,"33,38","17,71"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_014,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),12578,143,12770,"0,0111981206",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"26,13","14,37"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_016,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),10718,111,10853,"0,0102275868",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"26,16","14,35"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_018,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),10651,129,10799,"0,0119455505",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"26,1","14,88"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_019,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),10533,111,10671,"0,0104020242",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"26,05","14,66"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_020,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),6683,79,6768,"0,0116725768",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"26,07","14,18"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_021,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),10660,108,10783,"0,0100157656",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"26,09","14,35"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_022,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),13997,157,14178,"0,0110734941",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"26,07","14,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_023,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),13558,148,13742,"0,0107699025",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"26,04","14,66"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_041,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),35026,378,35560,"0,0106299213",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"26,04","14,78"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_025,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),18522,212,18768,"0,0112958227",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"26,04","14,29"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_026,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),14909,153,15107,"0,0101277553",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,26,"14,46"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_027,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),16590,183,16815,"0,0108831401",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"26,01","14,31"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_089,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),13688,151,13865,"0,0108907321",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,82","14,62"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),26683,272,27094,"0,0100391231",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"26,09","14,75"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_043,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),13331,145,13532,"0,0107153414",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"26,16","14,31"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_031,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),11872,126,12023,"0,0104799135",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,97","14,79"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),13648,141,13834,"0,0101922799",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"26,13","14,64"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_032,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),6017,84,6117,"0,0137322217",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,93","14,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),25907,295,26300,"0,01121673",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"26,05","14,34"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_033,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),12011,128,12173,"0,0105150743",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"26,08","14,55"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_034,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),4470,47,4527,"0,0103821515",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"26,09","14,74"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),30007,313,30450,"0,0102791461",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"26,05","14,56"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_035,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),23294,237,23583,"0,010049612",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"26,09","14,4"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_036,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),43332,471,43912,"0,0107259974",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"26,09","14,81"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),39992,439,40581,"0,0108178704",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"26,14","14,53"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_037,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),19177,196,19442,"0,0100812674",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"26,08","15,22"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),24042,252,24370,"0,0103405827",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"26,08","14,91"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),12099,148,12302,"0,0120305641",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"26,07","14,23"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),31672,339,32160,"0,0105410448",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"26,11","14,81"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),17592,188,17858,"0,0105274947",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"26,03","14,66"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),25456,284,25854,"0,0109847606",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"26,04","14,62"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),19500,198,19751,"0,0100248089",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"26,09","14,62"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_090,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),7769,85,7877,"0,0107909102",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,96","14,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),28332,305,28786,"0,0105954283",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"26,11","14,57"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_058,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),25159,299,25536,"0,0117089599",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"26,12","14,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_059,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),8971,145,9146,"0,0158539252",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,72","14,86"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_060,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),9907,166,10101,"0,0164340164",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,78","14,36"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_040,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),17886,196,18144,"0,0108024691",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"26,08","15,22"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_091,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),8750,114,8886,"0,0128291695",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,8","15,66"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_092,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),6233,72,6320,"0,0113924051",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,91","14,31"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_093,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),7918,95,8041,"0,0118144509",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,92","14,29"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),9968,156,10149,"0,0153709725",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,65","14,87"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),10778,181,10983,"0,0164800146",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,76","14,31"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),11651,183,11866,"0,0154222147",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,71","14,33"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),11919,243,12205,"0,019909873",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,76","14,88"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_065,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),6990,128,7135,"0,0179397337",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,75","14,3"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_066,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),6484,92,6596,"0,0139478472",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,63","14,72"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_067,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),7215,132,7370,"0,0179104478",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,82","14,48"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_068,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),7830,123,7981,"0,0154116026",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,71","14,73"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_069,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),10557,176,10763,"0,0163523181",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,67","14,24"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_070,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),6596,130,6742,"0,0192821121",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,72","14,58"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),9157,143,9330,"0,0153269025",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,72","14,34"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),11908,220,12172,"0,0180742688",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,83","14,25"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),7424,140,7600,"0,0184210526",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,72","14,44"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),4680,86,4774,"0,0180142438",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,95","14,4"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_075,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),12353,205,12605,"0,0162633875",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,8","14,61"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),7860,113,7991,"0,0141409085",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,89","14,24"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),6931,116,7072,"0,0164027149",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,75","14,52"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),9421,167,9612,"0,0173741157",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,69","14,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_079,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),5754,108,5884,"0,0183548606",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,83","14,59"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),9613,164,9805,"0,0167261601",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,85","14,74"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_081,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),13815,236,14115,"0,0167198016",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,74","14,68"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_082,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),8648,160,8837,"0,018105692",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,76","14,77"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),10789,189,11006,"0,0171724514",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,69","14,38"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),10476,205,10708,"0,0191445648",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,8","14,73"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_085,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),5711,102,5841,"0,0174627632",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,63","14,37"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),3994,73,4083,"0,0178790105",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,68","14,78"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_087,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),9800,167,9995,"0,0167083542",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,71","14,92"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_088,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),6897,124,7040,"0,0176136364",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,79","15,08"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_094,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),10922,117,11083,"0,0105567085",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,98","14,23"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_095,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),9279,96,9402,"0,0102105935",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,83","14,43"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_097,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),9410,123,9549,"0,0128809299",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"26,01","14,38"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_098,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),10235,104,10361,"0,0100376412",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,93","14,38"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_099,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),5446,61,5518,"0,01105473",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"26,09","14,85"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_101,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),9841,113,10000,"0,0113",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,92","14,31"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_102,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),9482,106,9610,"0,0110301769",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,96","14,93"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_103,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),10866,139,11020,"0,0126134301",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,96","14,77"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_104,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),10356,114,10488,"0,0108695652",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,92","14,44"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_105,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),9882,102,10008,"0,0101918465",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"26,1","14,42"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_106,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),17931,190,18170,"0,0104567969",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,96","14,73"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_108,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),14517,152,14721,"0,0103253855",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,96","14,59"
"low bq, bad alignment, low freq, many artifacts",UPN2_111,17,7578469,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly154Ala/c.461G>C|393|TP53|protein_coding|CODING|ENST00000269305|5|G),14763,171,14961,"0,0114297173",0,0,0,0,1,0,0,0,1,NO,NO,COSM46378,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"25,95","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_059,17,7578490,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val147Gly/c.440T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),8917,191,9207,"0,0207450853",0,0,0,0,1,0,0,0,1,NO,NO,COSM1644286. COSM1644284. COSM44309. COSM1644285,haematopoietic_and_lymphoid_tissue. biliary_tract. breast. stomach. urinary_tract,8. 3. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,22",Deleterious,0,Damaging,"28,46","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_060,17,7578490,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val147Gly/c.440T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),9849,193,10133,"0,0190466792",0,0,0,0,1,0,0,0,1,NO,NO,COSM1644286. COSM1644284. COSM44309. COSM1644285,haematopoietic_and_lymphoid_tissue. biliary_tract. breast. stomach. urinary_tract,8. 3. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,22",Deleterious,0,Damaging,"28,35","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_061,17,7578490,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val147Gly/c.440T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),9965,217,10257,"0,0211562835",0,0,0,0,1,0,0,0,1,NO,NO,COSM1644286. COSM1644284. COSM44309. COSM1644285,haematopoietic_and_lymphoid_tissue. biliary_tract. breast. stomach. urinary_tract,8. 3. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,22",Deleterious,0,Damaging,"28,45","15,01"
"low bq, many samples",UPN2_062,17,7578490,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val147Gly/c.440T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),10693,260,11042,"0,023546459",0,0,0,0,1,0,0,0,1,NO,NO,COSM1644286. COSM1644284. COSM44309. COSM1644285,haematopoietic_and_lymphoid_tissue. biliary_tract. breast. stomach. urinary_tract,8. 3. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,22",Deleterious,0,Damaging,"28,22","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_063,17,7578490,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val147Gly/c.440T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),11581,254,11942,"0,0212694691",0,0,0,0,1,0,0,0,1,NO,NO,COSM1644286. COSM1644284. COSM44309. COSM1644285,haematopoietic_and_lymphoid_tissue. biliary_tract. breast. stomach. urinary_tract,8. 3. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,22",Deleterious,0,Damaging,"28,46","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_064,17,7578490,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val147Gly/c.440T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),11940,242,12275,"0,0197148676",0,0,0,0,1,0,0,0,1,NO,NO,COSM1644286. COSM1644284. COSM44309. COSM1644285,haematopoietic_and_lymphoid_tissue. biliary_tract. breast. stomach. urinary_tract,8. 3. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,22",Deleterious,0,Damaging,"28,61","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_065,17,7578490,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val147Gly/c.440T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),7021,128,7199,"0,0177802473",0,0,0,0,1,0,0,0,1,NO,NO,COSM1644286. COSM1644284. COSM44309. COSM1644285,haematopoietic_and_lymphoid_tissue. biliary_tract. breast. stomach. urinary_tract,8. 3. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,22",Deleterious,0,Damaging,"28,42","15,61"
"low bq, low freq, many artifacts, many samples",UPN2_066,17,7578490,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val147Gly/c.440T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),6434,139,6649,"0,0209053993",0,0,0,0,1,0,0,0,1,NO,NO,COSM1644286. COSM1644284. COSM44309. COSM1644285,haematopoietic_and_lymphoid_tissue. biliary_tract. breast. stomach. urinary_tract,8. 3. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,22",Deleterious,0,Damaging,"28,48","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_067,17,7578490,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val147Gly/c.440T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),7204,136,7418,"0,0183337827",0,0,0,0,1,0,0,0,1,NO,NO,COSM1644286. COSM1644284. COSM44309. COSM1644285,haematopoietic_and_lymphoid_tissue. biliary_tract. breast. stomach. urinary_tract,8. 3. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,22",Deleterious,0,Damaging,"28,58","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_068,17,7578490,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val147Gly/c.440T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),7813,168,8056,"0,0208540218",0,0,0,0,1,0,0,0,1,NO,NO,COSM1644286. COSM1644284. COSM44309. COSM1644285,haematopoietic_and_lymphoid_tissue. biliary_tract. breast. stomach. urinary_tract,8. 3. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,22",Deleterious,0,Damaging,"28,52","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_069,17,7578490,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val147Gly/c.440T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),10522,233,10856,"0,0214627856",0,0,0,0,1,0,0,0,1,NO,NO,COSM1644286. COSM1644284. COSM44309. COSM1644285,haematopoietic_and_lymphoid_tissue. biliary_tract. breast. stomach. urinary_tract,8. 3. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,22",Deleterious,0,Damaging,"28,47","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_070,17,7578490,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val147Gly/c.440T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),6634,143,6833,"0,0209278501",0,0,0,0,1,0,0,0,1,NO,NO,COSM1644286. COSM1644284. COSM44309. COSM1644285,haematopoietic_and_lymphoid_tissue. biliary_tract. breast. stomach. urinary_tract,8. 3. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,22",Deleterious,0,Damaging,"28,35","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_071,17,7578490,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val147Gly/c.440T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),9140,190,9399,"0,0202149165",0,0,0,0,1,0,0,0,1,NO,NO,COSM1644286. COSM1644284. COSM44309. COSM1644285,haematopoietic_and_lymphoid_tissue. biliary_tract. breast. stomach. urinary_tract,8. 3. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,22",Deleterious,0,Damaging,"28,24","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_072,17,7578490,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val147Gly/c.440T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),11961,238,12279,"0,0193826859",0,0,0,0,1,0,0,0,1,NO,NO,COSM1644286. COSM1644284. COSM44309. COSM1644285,haematopoietic_and_lymphoid_tissue. biliary_tract. breast. stomach. urinary_tract,8. 3. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,22",Deleterious,0,Damaging,"28,43","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_073,17,7578490,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val147Gly/c.440T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),7459,147,7658,"0,0191956124",0,0,0,0,1,0,0,0,1,NO,NO,COSM1644286. COSM1644284. COSM44309. COSM1644285,haematopoietic_and_lymphoid_tissue. biliary_tract. breast. stomach. urinary_tract,8. 3. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,22",Deleterious,0,Damaging,"28,34","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_074,17,7578490,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val147Gly/c.440T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),4704,88,4831,"0,0182156903",0,0,0,0,1,0,0,0,1,NO,NO,COSM1644286. COSM1644284. COSM44309. COSM1644285,haematopoietic_and_lymphoid_tissue. biliary_tract. breast. stomach. urinary_tract,8. 3. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,22",Deleterious,0,Damaging,"28,19","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_075,17,7578490,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val147Gly/c.440T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),12406,243,12721,"0,0191022718",0,0,0,0,1,0,0,0,1,NO,NO,COSM1644286. COSM1644284. COSM44309. COSM1644285,haematopoietic_and_lymphoid_tissue. biliary_tract. breast. stomach. urinary_tract,8. 3. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,22",Deleterious,0,Damaging,"28,46","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_076,17,7578490,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val147Gly/c.440T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),7887,149,8084,"0,0184314696",0,0,0,0,1,0,0,0,1,NO,NO,COSM1644286. COSM1644284. COSM44309. COSM1644285,haematopoietic_and_lymphoid_tissue. biliary_tract. breast. stomach. urinary_tract,8. 3. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,22",Deleterious,0,Damaging,"28,36","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_077,17,7578490,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val147Gly/c.440T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),6923,138,7106,"0,0194202083",0,0,0,0,1,0,0,0,1,NO,NO,COSM1644286. COSM1644284. COSM44309. COSM1644285,haematopoietic_and_lymphoid_tissue. biliary_tract. breast. stomach. urinary_tract,8. 3. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,22",Deleterious,0,Damaging,"28,23","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_078,17,7578490,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val147Gly/c.440T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),9412,181,9666,"0,0187254293",0,0,0,0,1,0,0,0,1,NO,NO,COSM1644286. COSM1644284. COSM44309. COSM1644285,haematopoietic_and_lymphoid_tissue. biliary_tract. breast. stomach. urinary_tract,8. 3. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,22",Deleterious,0,Damaging,"28,16","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_079,17,7578490,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val147Gly/c.440T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),5745,125,5926,"0,0210934863",0,0,0,0,1,0,0,0,1,NO,NO,COSM1644286. COSM1644284. COSM44309. COSM1644285,haematopoietic_and_lymphoid_tissue. biliary_tract. breast. stomach. urinary_tract,8. 3. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,22",Deleterious,0,Damaging,"28,33","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_080,17,7578490,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val147Gly/c.440T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),9604,199,9903,"0,0200949207",0,0,0,0,1,0,0,0,1,NO,NO,COSM1644286. COSM1644284. COSM44309. COSM1644285,haematopoietic_and_lymphoid_tissue. biliary_tract. breast. stomach. urinary_tract,8. 3. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,22",Deleterious,0,Damaging,"28,49","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_081,17,7578490,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val147Gly/c.440T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),13856,287,14248,"0,020143178",0,0,0,0,1,0,0,0,1,NO,NO,COSM1644286. COSM1644284. COSM44309. COSM1644285,haematopoietic_and_lymphoid_tissue. biliary_tract. breast. stomach. urinary_tract,8. 3. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,22",Deleterious,0,Damaging,"28,57","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_082,17,7578490,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val147Gly/c.440T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),8676,168,8922,"0,0188298588",0,0,0,0,1,0,0,0,1,NO,NO,COSM1644286. COSM1644284. COSM44309. COSM1644285,haematopoietic_and_lymphoid_tissue. biliary_tract. breast. stomach. urinary_tract,8. 3. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,22",Deleterious,0,Damaging,"28,32","15,06"
"low bq, many samples",UPN2_083,17,7578490,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val147Gly/c.440T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),10744,244,11090,"0,0220018034",0,0,0,0,1,0,0,0,1,NO,NO,COSM1644286. COSM1644284. COSM44309. COSM1644285,haematopoietic_and_lymphoid_tissue. biliary_tract. breast. stomach. urinary_tract,8. 3. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,22",Deleterious,0,Damaging,"28,27","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_084,17,7578490,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val147Gly/c.440T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),10473,227,10781,"0,0210555607",0,0,0,0,1,0,0,0,1,NO,NO,COSM1644286. COSM1644284. COSM44309. COSM1644285,haematopoietic_and_lymphoid_tissue. biliary_tract. breast. stomach. urinary_tract,8. 3. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,22",Deleterious,0,Damaging,"28,48","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_085,17,7578490,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val147Gly/c.440T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),5727,117,5888,"0,0198709239",0,0,0,0,1,0,0,0,1,NO,NO,COSM1644286. COSM1644284. COSM44309. COSM1644285,haematopoietic_and_lymphoid_tissue. biliary_tract. breast. stomach. urinary_tract,8. 3. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,22",Deleterious,0,Damaging,"28,54","15,13"
"low bq, many samples",UPN2_086,17,7578490,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val147Gly/c.440T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),3971,103,4099,"0,02512808",0,0,0,0,1,0,0,0,1,NO,NO,COSM1644286. COSM1644284. COSM44309. COSM1644285,haematopoietic_and_lymphoid_tissue. biliary_tract. breast. stomach. urinary_tract,8. 3. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,22",Deleterious,0,Damaging,"28,46","14,44"
"low bq, many samples",UPN2_087,17,7578490,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val147Gly/c.440T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),9737,225,10041,"0,0224081267",0,0,0,0,1,0,0,0,1,NO,NO,COSM1644286. COSM1644284. COSM44309. COSM1644285,haematopoietic_and_lymphoid_tissue. biliary_tract. breast. stomach. urinary_tract,8. 3. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,22",Deleterious,0,Damaging,"28,53","14,89"
"low bq, low freq, many artifacts",UPN2_088,17,7578490,A,C,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val147Gly/c.440T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),6899,139,7093,"0,0195967856",0,0,0,0,1,0,0,0,1,NO,NO,COSM1644286. COSM1644284. COSM44309. COSM1644285,haematopoietic_and_lymphoid_tissue. biliary_tract. breast. stomach. urinary_tract,8. 3. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-6,22",Deleterious,0,Damaging,"28,53","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_059,17,7578494,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp146Gly/c.436T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),9002,145,9195,"0,0157694399",0,0,0,0,1,0,0,0,1,NO,NO,COSM44555,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,109,Tolerated,"27,87","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_060,17,7578494,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp146Gly/c.436T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),9917,161,10124,"0,0159028052",0,0,0,0,1,0,0,0,1,NO,NO,COSM44555,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,109,Tolerated,"27,76","15,76"
"low bq, low freq, many artifacts, many samples",UPN2_061,17,7578494,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp146Gly/c.436T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),10024,173,10242,"0,0168912322",0,0,0,0,1,0,0,0,1,NO,NO,COSM44555,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,109,Tolerated,"27,85","15,34"
"low bq, low freq, many artifacts, many samples",UPN2_062,17,7578494,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp146Gly/c.436T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),10792,160,11032,"0,0145032632",0,0,0,0,1,0,0,0,1,NO,NO,COSM44555,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,109,Tolerated,"27,68","15,6"
"low bq, low freq, many artifacts, many samples",UPN2_063,17,7578494,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp146Gly/c.436T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),11644,232,11927,"0,0194516643",0,0,0,0,1,0,0,0,1,NO,NO,COSM44555,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,109,Tolerated,"27,72","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_064,17,7578494,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp146Gly/c.436T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),12001,177,12257,"0,0144407277",0,0,0,0,1,0,0,0,1,NO,NO,COSM44555,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,109,Tolerated,"27,81","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_065,17,7578494,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp146Gly/c.436T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),7011,127,7183,"0,0176806348",0,0,0,0,1,0,0,0,1,NO,NO,COSM44555,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,109,Tolerated,"27,94","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_066,17,7578494,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp146Gly/c.436T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),6466,128,6640,"0,0192771084",0,0,0,0,1,0,0,0,1,NO,NO,COSM44555,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,109,Tolerated,"27,84","15,17"
"low bq, low freq, many artifacts, many samples",UPN2_067,17,7578494,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp146Gly/c.436T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),7270,106,7413,"0,0142992041",0,0,0,0,1,0,0,0,1,NO,NO,COSM44555,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,109,Tolerated,"27,72","15,4"
"low bq, low freq, many artifacts, many samples",UPN2_068,17,7578494,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp146Gly/c.436T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),7874,124,8040,"0,0154228856",0,0,0,0,1,0,0,0,1,NO,NO,COSM44555,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,109,Tolerated,"27,9","15,31"
"low bq, low freq, many artifacts, many samples",UPN2_069,17,7578494,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp146Gly/c.436T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),10571,204,10842,"0,0188157167",0,0,0,0,1,0,0,0,1,NO,NO,COSM44555,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,109,Tolerated,"27,76","15,4"
"low bq, low freq, many artifacts, many samples",UPN2_070,17,7578494,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp146Gly/c.436T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),6661,141,6824,"0,0206623681",0,0,0,0,1,0,0,0,1,NO,NO,COSM44555,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,109,Tolerated,"27,8","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_071,17,7578494,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp146Gly/c.436T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),9161,159,9381,"0,0169491525",0,0,0,0,1,0,0,0,1,NO,NO,COSM44555,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,109,Tolerated,"27,84","15,77"
"low bq, low freq, many artifacts, many samples",UPN2_072,17,7578494,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp146Gly/c.436T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),11994,201,12267,"0,0163854243",0,0,0,0,1,0,0,0,1,NO,NO,COSM44555,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,109,Tolerated,"27,67","15,77"
"low bq, low freq, many artifacts, many samples",UPN2_073,17,7578494,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp146Gly/c.436T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),7475,127,7650,"0,0166013072",0,0,0,0,1,0,0,0,1,NO,NO,COSM44555,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,109,Tolerated,"27,55","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_074,17,7578494,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp146Gly/c.436T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),4702,78,4826,"0,0161624534",0,0,0,0,1,0,0,0,1,NO,NO,COSM44555,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,109,Tolerated,"27,67","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_075,17,7578494,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp146Gly/c.436T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),12421,213,12711,"0,0167571395",0,0,0,0,1,0,0,0,1,NO,NO,COSM44555,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,109,Tolerated,"27,68","16,1"
"low bq, low freq, many artifacts, many samples",UPN2_076,17,7578494,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp146Gly/c.436T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),7883,144,8079,"0,0178239881",0,0,0,0,1,0,0,0,1,NO,NO,COSM44555,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,109,Tolerated,"27,86","15,17"
"low bq, low freq, many artifacts, many samples",UPN2_077,17,7578494,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp146Gly/c.436T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),6952,112,7100,"0,0157746479",0,0,0,0,1,0,0,0,1,NO,NO,COSM44555,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,109,Tolerated,"27,54","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_078,17,7578494,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp146Gly/c.436T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),9413,166,9652,"0,0171985081",0,0,0,0,1,0,0,0,1,NO,NO,COSM44555,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,109,Tolerated,"27,72","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_079,17,7578494,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp146Gly/c.436T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),5775,111,5918,"0,0187563366",0,0,0,0,1,0,0,0,1,NO,NO,COSM44555,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,109,Tolerated,"27,65","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_080,17,7578494,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp146Gly/c.436T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),9665,157,9890,"0,0158746208",0,0,0,0,1,0,0,0,1,NO,NO,COSM44555,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,109,Tolerated,"27,72","15,87"
"low bq, low freq, many artifacts, many samples",UPN2_081,17,7578494,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp146Gly/c.436T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),13925,205,14233,"0,0144031476",0,0,0,0,1,0,0,0,1,NO,NO,COSM44555,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,109,Tolerated,"27,79","15,48"
"low bq, low freq, many artifacts, many samples",UPN2_082,17,7578494,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp146Gly/c.436T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),8700,155,8912,"0,0173922801",0,0,0,0,1,0,0,0,1,NO,NO,COSM44555,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,109,Tolerated,"27,92","15,65"
"low bq, low freq, many artifacts, many samples",UPN2_083,17,7578494,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp146Gly/c.436T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),10802,205,11077,"0,0185068159",0,0,0,0,1,0,0,0,1,NO,NO,COSM44555,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,109,Tolerated,"27,73","15,57"
"low bq, low freq, many artifacts, many samples",UPN2_084,17,7578494,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp146Gly/c.436T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),10470,202,10768,"0,0187592868",0,0,0,0,1,0,0,0,1,NO,NO,COSM44555,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,109,Tolerated,"27,78","16,11"
"low bq, low freq, many artifacts, many samples",UPN2_085,17,7578494,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp146Gly/c.436T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),5729,107,5881,"0,0181941847",0,0,0,0,1,0,0,0,1,NO,NO,COSM44555,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,109,Tolerated,"27,9","17,38"
"low bq, low freq, many artifacts, many samples",UPN2_086,17,7578494,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp146Gly/c.436T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),3983,81,4094,"0,0197850513",0,0,0,0,1,0,0,0,1,NO,NO,COSM44555,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,109,Tolerated,"27,76","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_087,17,7578494,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp146Gly/c.436T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),9814,149,10025,"0,0148628429",0,0,0,0,1,0,0,0,1,NO,NO,COSM44555,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,109,Tolerated,"27,84","14,97"
"low bq, low freq, many artifacts",UPN2_088,17,7578494,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp146Gly/c.436T>G|393|TP53|protein_coding|CODING|ENST00000269305|5|C),6945,92,7088,"0,012979684",0,0,0,0,1,0,0,0,1,NO,NO,COSM44555,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,109,Tolerated,"27,53","15,14"
"low bq, many samples, no database",UPN2_001,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),3515,44,3574,"0,012311136",0,0,0,0,1,0,0,1,2,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"32,93","28,68"
"low bq, many samples, no database",UPN2_014,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),6416,72,6521,"0,0110412513",0,0,0,0,1,0,0,1,2,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"31,5","27,44"
"low bq, low freq, many artifacts, many samples",UPN2_016,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),5454,68,5540,"0,0122743682",0,0,0,0,1,0,0,0,1,NO,NO,COSM3522708. COSM3522705. COSM45382. COSM3522707. COSM3522706,oesophagus. skin. breast. large_intestine. lung. upper_aerodigestive_tract. urinary_tract,5. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"31,35",23
"low bq, many samples, no database",UPN2_018,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),5440,70,5530,"0,0126582278",0,0,0,0,1,0,0,1,2,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"31,34","26,84"
"low bq, many samples, no database",UPN2_019,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),5361,91,5472,"0,016630117",0,0,0,0,1,0,0,1,2,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"31,35","26,78"
"low bq, many samples, no database",UPN2_020,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),3419,65,3490,"0,0186246418",0,0,0,0,1,1,0,1,3,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"31,4","27,83"
"low bq, low freq, many artifacts, many samples",UPN2_002,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),5540,79,5634,"0,0140220092",0,0,0,0,1,0,0,0,1,NO,NO,COSM3522708. COSM3522705. COSM45382. COSM3522707. COSM3522706,oesophagus. skin. breast. large_intestine. lung. upper_aerodigestive_tract. urinary_tract,5. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"32,86","26,03"
"low bq, many samples, no database",UPN2_022,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),7141,127,7298,"0,017402028",0,0,0,0,1,1,0,1,3,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"31,2","27,69"
"low bq, low freq, many artifacts, many samples",UPN2_041,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),17858,229,18213,"0,0125734366",0,0,0,0,1,0,0,0,1,NO,NO,COSM3522708. COSM3522705. COSM45382. COSM3522707. COSM3522706,oesophagus. skin. breast. large_intestine. lung. upper_aerodigestive_tract. urinary_tract,5. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"32,24","24,29"
"low bq, many samples, no database",UPN2_024,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),2919,46,2969,"0,0154934321",0,0,0,0,1,0,0,1,2,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"31,42","27,02"
"low bq, many samples, no database",UPN2_026,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),7590,116,7748,"0,0149716056",0,0,0,0,1,0,0,1,2,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"31,32","25,72"
"low bq, low freq, many artifacts, many samples",UPN2_043,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),6818,73,6923,"0,0105445616",0,0,0,0,1,0,0,0,1,NO,NO,COSM3522708. COSM3522705. COSM45382. COSM3522707. COSM3522706,oesophagus. skin. breast. large_intestine. lung. upper_aerodigestive_tract. urinary_tract,5. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"32,27","22,36"
"low bq, low freq, many artifacts, many samples",UPN2_031,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),6040,64,6128,"0,0104438642",0,0,0,0,1,0,0,0,1,NO,NO,COSM3522708. COSM3522705. COSM45382. COSM3522707. COSM3522706,oesophagus. skin. breast. large_intestine. lung. upper_aerodigestive_tract. urinary_tract,5. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"31,28","21,66"
"low bq, many samples, no database",UPN2_005,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),1263,28,1294,"0,0216383308",0,0,0,0,1,0,0,1,2,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"32,8","28,32"
"low bq, low freq, many artifacts, many samples",UPN2_032,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),3058,42,3116,"0,013478819",0,0,0,0,1,0,0,0,1,NO,NO,COSM3522708. COSM3522705. COSM45382. COSM3522707. COSM3522706,oesophagus. skin. breast. large_intestine. lung. upper_aerodigestive_tract. urinary_tract,5. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"31,33","23,81"
"low bq, many samples, no database",UPN2_047,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),15365,230,15665,"0,014682413",0,0,0,0,1,0,0,1,2,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"32,2","25,91"
"low bq, low freq, many artifacts, many samples",UPN2_048,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),15764,165,15988,"0,0103202402",0,0,0,0,1,0,0,0,1,NO,NO,COSM3522708. COSM3522705. COSM45382. COSM3522707. COSM3522706,oesophagus. skin. breast. large_intestine. lung. upper_aerodigestive_tract. urinary_tract,5. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"32,3","23,42"
"low bq, many samples, no database",UPN2_036,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),22152,364,22590,"0,0161133245",0,0,0,0,1,1,0,1,3,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"31,43","27,76"
"low bq, many samples, no database",UPN2_037,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),9776,105,9915,"0,0105900151",0,0,0,0,1,0,0,1,2,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"31,37","26,56"
"low bq, low freq, many artifacts, many samples",UPN2_051,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),12271,130,12469,"0,0104258561",0,0,0,0,1,0,0,0,1,NO,NO,COSM3522708. COSM3522705. COSM45382. COSM3522707. COSM3522706,oesophagus. skin. breast. large_intestine. lung. upper_aerodigestive_tract. urinary_tract,5. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"32,42","24,48"
"low bq, many samples, no database",UPN2_038,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),11342,216,11606,"0,0186110632",0,0,0,0,1,1,0,1,3,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"31,28","26,64"
"low bq, many samples, no database",UPN2_008,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),14572,213,14833,"0,0143598733",0,0,0,0,1,1,1,1,4,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"32,73","28,13"
"low bq, many samples, no database",UPN2_009,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),12235,125,12406,"0,0100757698",0,0,1,0,1,0,1,0,3,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"32,65","23,18"
"low bq, many samples, no database",UPN2_010,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),9240,191,9467,"0,0201753459",0,0,0,0,1,1,0,1,3,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"32,72","28,2"
"low bq, many samples, no database",UPN2_058,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),12884,169,13109,"0,0128919063",0,0,0,0,1,0,0,1,2,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"32,21","25,67"
"low bq, many samples, no database",UPN2_059,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),4622,190,4826,"0,0393700787",0,0,0,0,1,1,0,1,3,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"31,72","26,78"
"low bq, many samples, no database",UPN2_012,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),4497,129,4639,"0,0278077172",0,0,0,0,1,1,0,1,3,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"32,8","29,6"
"low bq, many samples, no database",UPN2_060,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),5086,214,5327,"0,0401727051",0,0,0,0,1,1,0,1,3,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"31,64","27,44"
"low bq, many samples, no database",UPN2_040,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),9149,138,9333,"0,0147862424",0,0,0,0,1,0,0,1,2,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"31,38","26,99"
"low bq, many samples, no database",UPN2_013,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),2718,39,2777,"0,0140439323",0,0,0,0,1,0,0,1,2,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"32,64","27,46"
"low bq, many samples, no database",UPN2_091,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),4470,54,4544,"0,0118838028",0,0,0,0,1,0,0,1,2,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"32,73","27,04"
"low bq, many samples, no database",UPN2_062,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),5600,207,5828,"0,0355181881",0,0,0,0,1,1,0,1,3,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"31,65","26,83"
"low bq, many samples, no database",UPN2_063,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),6014,218,6257,"0,0348409781",0,0,0,0,1,1,0,1,3,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"31,48","27,32"
"low bq, many samples, no database",UPN2_064,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),6172,144,6335,"0,0227308603",0,0,0,0,1,1,0,1,3,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"31,45","26,35"
"low bq, many samples, no database",UPN2_065,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),3603,214,3830,"0,0558746736",0,0,0,0,1,1,0,1,3,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"31,47","27,27"
"low bq, many samples, no database",UPN2_066,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),3358,189,3568,"0,052970852",0,0,0,0,1,1,0,1,3,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"31,55","27,9"
"low bq, many samples, no database",UPN2_067,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),3737,116,3862,"0,0300362506",0,0,0,0,1,1,0,1,3,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"31,59","28,05"
"low bq, many samples, no database",UPN2_068,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),4043,104,4166,"0,0249639942",0,0,0,0,1,1,0,0,2,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"31,58","24,16"
"low bq, many samples, no database",UPN2_069,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),5450,155,5618,"0,0275898896",0,0,0,0,1,1,0,0,2,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"31,7","25,57"
"low bq, low freq, many artifacts, many samples",UPN2_070,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),3446,59,3511,"0,0168043293",0,0,0,0,1,0,0,0,1,NO,NO,COSM3522708. COSM3522705. COSM45382. COSM3522707. COSM3522706,oesophagus. skin. breast. large_intestine. lung. upper_aerodigestive_tract. urinary_tract,5. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"31,64","24,44"
"low bq, low freq, many artifacts, many samples",UPN2_071,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),4700,67,4793,"0,013978719",0,0,0,0,1,0,0,0,1,NO,NO,COSM3522708. COSM3522705. COSM45382. COSM3522707. COSM3522706,oesophagus. skin. breast. large_intestine. lung. upper_aerodigestive_tract. urinary_tract,5. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"31,62","23,54"
"low bq, low freq, many artifacts, many samples",UPN2_072,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),6158,89,6276,"0,014181007",0,0,0,0,1,0,0,0,1,NO,NO,COSM3522708. COSM3522705. COSM45382. COSM3522707. COSM3522706,oesophagus. skin. breast. large_intestine. lung. upper_aerodigestive_tract. urinary_tract,5. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"31,52","23,46"
"low bq, low freq, many artifacts, many samples",UPN2_073,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),3843,74,3931,"0,0188247265",0,0,0,0,1,0,0,0,1,NO,NO,COSM3522708. COSM3522705. COSM45382. COSM3522707. COSM3522706,oesophagus. skin. breast. large_intestine. lung. upper_aerodigestive_tract. urinary_tract,5. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"31,38","23,7"
"low bq, many samples, no database",UPN2_074,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),2436,141,2580,"0,0546511628",0,0,0,0,1,1,0,1,3,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"31,48","28,77"
"low bq, many samples, no database",UPN2_075,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),6387,216,6620,"0,0326283988",0,0,0,0,1,1,0,1,3,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"31,63","25,84"
"low bq, low freq, many artifacts, many samples",UPN2_076,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),4061,60,4135,"0,0145102781",0,0,0,0,1,0,0,0,1,NO,NO,COSM3522708. COSM3522705. COSM45382. COSM3522707. COSM3522706,oesophagus. skin. breast. large_intestine. lung. upper_aerodigestive_tract. urinary_tract,5. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"31,7","25,3"
"low bq, many samples, no database",UPN2_077,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),3562,145,3723,"0,0389470857",0,0,0,0,1,1,0,1,3,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"31,45","25,92"
"low bq, low freq, many artifacts",UPN2_079,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),2974,56,3044,"0,0183968463",0,0,0,0,1,0,0,0,1,NO,NO,COSM3522708. COSM3522705. COSM45382. COSM3522707. COSM3522706,oesophagus. skin. breast. large_intestine. lung. upper_aerodigestive_tract. urinary_tract,5. 5. 1. 1. 1. 1. 1,NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"31,57","25,8"
"low bq, many samples, no database",UPN2_081,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),7200,201,7422,"0,0270816492",0,0,0,0,1,1,0,1,3,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"31,49",27
"low bq, many samples, no database",UPN2_082,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),4499,173,4681,"0,036957915",0,0,0,0,1,1,0,1,3,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"31,52","27,91"
"low bq, many samples, no database",UPN2_083,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),5567,121,5704,"0,0212131837",0,0,0,0,1,1,0,0,2,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"31,67","25,35"
"low bq, many samples, no database",UPN2_084,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),5422,141,5590,"0,0252236136",0,0,0,0,1,1,0,1,3,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"31,68","27,36"
"low bq, many samples, no database",UPN2_085,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),2968,162,3146,"0,0514939606",0,0,0,0,1,1,0,1,3,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"31,59","28,05"
"low bq, many samples, no database",UPN2_086,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),2068,184,2259,"0,0814519699",0,0,0,1,1,1,0,1,4,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"31,68","26,43"
"low bq, many samples, no database",UPN2_087,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),5058,182,5256,"0,0346270928",0,0,0,0,1,1,0,1,3,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"31,78","26,64"
"low bq, many samples, no database",UPN2_088,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),3583,117,3711,"0,0315278901",0,0,0,0,1,1,0,1,3,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"31,25","27,24"
"low bq, many samples, no database",UPN2_094,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),5578,63,5661,"0,0111287758",0,0,0,0,1,0,0,1,2,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"32,92","26,89"
"low bq, many samples, no database",UPN2_098,17,7578502,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val143Glu/c.428T>A|393|TP53|protein_coding|CODING|ENST00000269305|5|T),5228,56,5307,"0,010552101",0,0,0,0,1,0,0,1,2,NO,NO,"COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1",NO,NO,NO,NO,NO,NO,"-5,75",Deleterious,0,Damaging,"32,97","27,61"
"low freq, many artifacts",UPN2_090,17,7579317,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys124Ser/c.370T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),1649,22,1676,"0,0131264916",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,88",Neutral,"0,463",Tolerated,"35,77","35,82"
"low bq, low freq, many artifacts, many samples",UPN2_072,17,7579349,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe113Cys/c.338T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),2534,34,2578,"0,0131885182",0,0,0,0,1,0,0,0,1,NO,NO,COSM10717. COSM2745003. COSM287502. COSM4139893. COSM287503,breast. large_intestine. liver. lung. oesophagus. ovary,6. 8. 5. 4. 5. 7,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"31,28","16,35"
"low bq, low freq, many artifacts, many samples",UPN2_081,17,7579349,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe113Cys/c.338T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),3451,35,3493,"0,0100200401",0,0,0,0,1,0,0,0,1,NO,NO,COSM10717. COSM2745003. COSM287502. COSM4139893. COSM287503,breast. large_intestine. liver. lung. oesophagus. ovary,6. 8. 5. 4. 5. 7,NO,NO,NO,NO,NO,NO,"-7,13",Deleterious,0,Damaging,"31,37","16,37"
"low freq, many artifacts",UPN2_006,17,7579351,GC,G,frameshift_variant(HIGH||ggc/|p.Gly112fs/c.335delG|393|TP53|protein_coding|CODING|ENST00000269305|4|G),1897,26,1924,"0,0135135135",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,34",NA
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,17,7579362,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe109Val/c.325T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),2094,31,2133,"0,0145335209",0,0,0,0,1,0,0,0,1,NO,NO,COSM3970390. COSM3970388. COSM3970389. COSM3970387. COSM48817,central_nervous_system. liver. lung,5. 6. 1,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,1,Damaging,"26,47","15,58"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,17,7579362,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe109Val/c.325T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1296,22,1330,"0,0165413534",0,0,0,0,1,0,0,0,1,NO,NO,COSM3970390. COSM3970388. COSM3970389. COSM3970387. COSM48817,central_nervous_system. liver. lung,5. 6. 1,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,1,Damaging,"26,29","14,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,17,7579362,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe109Val/c.325T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),2411,36,2458,"0,0146460537",0,0,0,0,1,0,0,0,1,NO,NO,COSM3970390. COSM3970388. COSM3970389. COSM3970387. COSM48817,central_nervous_system. liver. lung,5. 6. 1,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,1,Damaging,"26,73","14,61"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,17,7579362,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe109Val/c.325T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),2521,36,2578,"0,0139643134",0,0,0,0,1,0,0,0,1,NO,NO,COSM3970390. COSM3970388. COSM3970389. COSM3970387. COSM48817,central_nervous_system. liver. lung,5. 6. 1,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,1,Damaging,"26,59","14,97"
"low bq, bad alignment, many samples",UPN2_076,17,7579362,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe109Val/c.325T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),885,25,915,"0,0273224044",0,0,0,0,1,0,0,0,1,NO,NO,COSM3970390. COSM3970388. COSM3970389. COSM3970387. COSM48817,central_nervous_system. liver. lung,5. 6. 1,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,1,Damaging,"26,65","14,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,17,7579362,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe109Val/c.325T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1633,25,1672,"0,0149521531",0,0,0,0,1,0,0,0,1,NO,NO,COSM3970390. COSM3970388. COSM3970389. COSM3970387. COSM48817,central_nervous_system. liver. lung,5. 6. 1,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,1,Damaging,"26,59","15,04"
"low bq, bad alignment, low freq, many artifacts",UPN2_081,17,7579362,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe109Val/c.325T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),3421,52,3491,"0,0148954454",0,0,0,0,1,0,0,0,1,NO,NO,COSM3970390. COSM3970388. COSM3970389. COSM3970387. COSM48817,central_nervous_system. liver. lung,5. 6. 1,NO,NO,NO,NO,NO,NO,"-5,79",Deleterious,1,Damaging,"26,86","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_062,17,7579376,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln104Pro/c.311A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),2097,24,2132,"0,0112570356",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"4,76",Neutral,1,Tolerated,"29,09","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_078,17,7579376,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln104Pro/c.311A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),1262,28,1293,"0,0216550657",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"4,76",Neutral,1,Tolerated,"29,55","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_052,17,7579379,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr103Ser/c.308A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),3105,35,3155,"0,0110935024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,0,Damaging,"31,29",14
"low bq, low freq, many artifacts, many samples",UPN2_061,17,7579379,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr103Ser/c.308A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),1069,22,1097,"0,0200546946",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,0,Damaging,"29,05","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_062,17,7579379,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr103Ser/c.308A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),2075,40,2131,"0,0187705303",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,0,Damaging,"28,76",14
"low bq, low freq, many artifacts, many samples",UPN2_063,17,7579379,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr103Ser/c.308A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),1302,25,1330,"0,0187969925",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,0,Damaging,"29,03","15,32"
"low bq, many samples",UPN2_071,17,7579379,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr103Ser/c.308A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),2392,56,2456,"0,0228013029",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,0,Damaging,"29,06","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_072,17,7579379,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr103Ser/c.308A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),2515,54,2578,"0,0209464701",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,0,Damaging,"28,69","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_075,17,7579379,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr103Ser/c.308A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),1772,30,1811,"0,0165654335",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,0,Damaging,"29,17","15,43"
"low bq, many samples",UPN2_076,17,7579379,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr103Ser/c.308A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),884,25,914,"0,0273522976",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,0,Damaging,"28,15","14,8"
"low bq, many samples",UPN2_078,17,7579379,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr103Ser/c.308A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),1250,39,1293,"0,030162413",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,0,Damaging,"28,6","14,18"
"low bq, many samples",UPN2_080,17,7579379,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr103Ser/c.308A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),1631,37,1672,"0,0221291866",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,0,Damaging,"28,52","14,73"
"low bq, many samples",UPN2_081,17,7579379,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr103Ser/c.308A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),3387,87,3490,"0,0249283668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,0,Damaging,"28,85","14,9"
"low bq, many samples",UPN2_083,17,7579379,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr103Ser/c.308A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),994,27,1023,"0,0263929619",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,0,Damaging,"28,83","14,26"
low bq,UPN2_084,17,7579379,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr103Ser/c.308A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),896,24,925,"0,0259459459",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,55",Deleterious,0,Damaging,"28,33",14
"low bq, low freq, many artifacts, many samples",UPN2_014,17,7579383,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr102Pro/c.304A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),3379,38,3443,"0,0110368864",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,16,Damaging,"29,38","20,84"
"low bq, low freq, many artifacts, many samples",UPN2_021,17,7579383,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr102Pro/c.304A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),2960,33,3026,"0,0109054858",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,16,Damaging,"28,71","16,09"
"low bq, low freq, many artifacts, many samples",UPN2_041,17,7579383,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr102Pro/c.304A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),6575,67,6696,"0,0100059737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,16,Damaging,"30,28","19,07"
"low bq, low freq, many artifacts, many samples",UPN2_024,17,7579383,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr102Pro/c.304A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),1556,21,1592,"0,0131909548",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,16,Damaging,"29,22","16,86"
"low bq, low freq, many artifacts, many samples",UPN2_026,17,7579383,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr102Pro/c.304A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),4366,51,4452,"0,0114555256",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,16,Damaging,"29,05",20
"low bq, low freq, many artifacts, many samples",UPN2_042,17,7579383,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr102Pro/c.304A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),6398,79,6528,"0,0121017157",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,16,Damaging,"30,44","18,96"
"low bq, low freq, many artifacts, many samples",UPN2_043,17,7579383,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr102Pro/c.304A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),3757,41,3843,"0,0106687484",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,16,Damaging,"30,55","17,98"
"low bq, low freq, many artifacts, many samples",UPN2_031,17,7579383,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr102Pro/c.304A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),2682,32,2735,"0,0117001828",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,16,Damaging,"29,25","19,72"
"low bq, low freq, many artifacts, many samples",UPN2_046,17,7579383,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr102Pro/c.304A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),6924,83,7077,"0,0117281334",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,16,Damaging,"30,19","18,59"
"low bq, low freq, many artifacts, many samples",UPN2_047,17,7579383,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr102Pro/c.304A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),7155,87,7326,"0,0118755119",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,16,Damaging,"30,15","20,06"
"low bq, low freq, many artifacts, many samples",UPN2_048,17,7579383,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr102Pro/c.304A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),6738,75,6856,"0,0109393232",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,16,Damaging,"30,16","19,55"
"low bq, low freq, many artifacts, many samples",UPN2_006,17,7579383,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr102Pro/c.304A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),1886,23,1923,"0,0119604784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,16,Damaging,"29,09","15,91"
"low bq, low freq, many artifacts, many samples",UPN2_049,17,7579383,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr102Pro/c.304A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),4234,54,4329,"0,0124740125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,16,Damaging,"30,17","16,78"
"low bq, low freq, many artifacts, many samples",UPN2_051,17,7579383,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr102Pro/c.304A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),5516,60,5624,"0,0106685633",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,16,Damaging,"30,6","17,65"
"low bq, low freq, many artifacts, many samples",UPN2_039,17,7579383,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr102Pro/c.304A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),12659,131,12898,"0,0101566134",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,16,Damaging,"28,67","19,57"
"low bq, low freq, many artifacts, many samples",UPN2_053,17,7579383,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr102Pro/c.304A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),6069,73,6193,"0,011787502",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,16,Damaging,"30,31","17,21"
"low bq, low freq, many artifacts, many samples",UPN2_054,17,7579383,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr102Pro/c.304A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),4207,51,4300,"0,0118604651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,16,Damaging,"30,02","19,43"
"low bq, low freq, many artifacts, many samples",UPN2_007,17,7579383,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr102Pro/c.304A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),4736,49,4843,"0,0101176956",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,16,Damaging,"29,44","17,43"
"low bq, low freq, many artifacts, many samples",UPN2_008,17,7579383,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr102Pro/c.304A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),6822,96,6973,"0,0137673885",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,16,Damaging,29,"16,08"
"low bq, low freq, many artifacts, many samples",UPN2_009,17,7579383,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr102Pro/c.304A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),5511,65,5618,"0,0115699537",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,16,Damaging,"29,25","15,74"
"low bq, low freq, many artifacts, many samples",UPN2_011,17,7579383,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr102Pro/c.304A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),3656,43,3725,"0,0115436242",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,16,Damaging,"29,27","17,91"
"low bq, low freq, many artifacts, many samples",UPN2_056,17,7579383,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr102Pro/c.304A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),3990,51,4073,"0,0125214829",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,16,Damaging,"30,2","17,71"
"low bq, low freq, many artifacts, many samples",UPN2_057,17,7579383,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr102Pro/c.304A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),3463,46,3541,"0,0129906806",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,16,Damaging,"30,55","17,43"
"low bq, low freq, many artifacts, many samples",UPN2_058,17,7579383,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr102Pro/c.304A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),7132,81,7286,"0,0111172111",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,16,Damaging,"30,33","18,54"
"low bq, many samples",UPN2_061,17,7579383,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr102Pro/c.304A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),1055,38,1097,"0,0346399271",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,16,Damaging,"27,41","16,84"
"low bq, many samples",UPN2_062,17,7579383,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr102Pro/c.304A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),2042,74,2131,"0,034725481",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,16,Damaging,"27,09","15,61"
"low bq, many samples",UPN2_063,17,7579383,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr102Pro/c.304A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),1289,36,1330,"0,0270676692",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,16,Damaging,"27,33","14,89"
"low bq, many samples",UPN2_064,17,7579383,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr102Pro/c.304A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),862,35,903,"0,0387596899",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,16,Damaging,"27,78","17,23"
"low bq, bad alignment, many samples",UPN2_071,17,7579383,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr102Pro/c.304A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),2367,78,2456,"0,0317589577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,16,Damaging,"26,72","14,85"
"low bq, bad alignment, many samples",UPN2_072,17,7579383,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr102Pro/c.304A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),2484,80,2577,"0,0310438494",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,16,Damaging,"26,93","15,31"
"low bq, many samples",UPN2_075,17,7579383,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr102Pro/c.304A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),1746,49,1810,"0,0270718232",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,16,Damaging,"27,58","15,61"
"low bq, many samples",UPN2_076,17,7579383,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr102Pro/c.304A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),872,31,914,"0,033916849",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,16,Damaging,"27,02","14,94"
"low bq, bad alignment, many samples",UPN2_078,17,7579383,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr102Pro/c.304A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),1232,48,1292,"0,0371517028",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,16,Damaging,"26,52","15,92"
"low bq, many samples",UPN2_079,17,7579383,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr102Pro/c.304A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),688,28,718,"0,0389972145",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,16,Damaging,"27,09",17
"low bq, bad alignment, many samples",UPN2_080,17,7579383,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr102Pro/c.304A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),1617,44,1672,"0,0263157895",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,16,Damaging,"26,7","14,95"
"low bq, many samples",UPN2_081,17,7579383,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr102Pro/c.304A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),3352,116,3490,"0,0332378223",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,16,Damaging,"27,01","14,77"
"low bq, bad alignment, many samples",UPN2_083,17,7579383,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr102Pro/c.304A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),980,31,1023,"0,0303030303",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,16,Damaging,"26,99","15,35"
"low bq, bad alignment",UPN2_084,17,7579383,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr102Pro/c.304A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),890,31,925,"0,0335135135",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,16,Damaging,"26,42","15,65"
"low bq, low freq, many artifacts, many samples",UPN2_061,17,7579384,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys101Asn/c.303A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),1068,21,1097,"0,0191431176",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,34",Neutral,74,Tolerated,"28,05",14
"low bq, low freq, many artifacts, many samples",UPN2_062,17,7579384,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys101Asn/c.303A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),2079,39,2131,"0,018301267",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,34",Neutral,74,Tolerated,"28,44","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_063,17,7579384,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys101Asn/c.303A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),1303,23,1329,"0,0173062453",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,34",Neutral,74,Tolerated,"28,74","15,52"
"low bq, low freq, many artifacts, many samples",UPN2_071,17,7579384,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys101Asn/c.303A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),2385,50,2456,"0,0203583062",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,34",Neutral,74,Tolerated,"28,58","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_072,17,7579384,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys101Asn/c.303A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),2515,44,2577,"0,0170741172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,34",Neutral,74,Tolerated,"28,11","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_075,17,7579384,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys101Asn/c.303A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),1773,27,1810,"0,0149171271",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,34",Neutral,74,Tolerated,"28,32","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_078,17,7579384,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys101Asn/c.303A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),1263,22,1292,"0,0170278638",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,34",Neutral,74,Tolerated,"28,51","15,27"
"low bq, many samples",UPN2_080,17,7579384,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys101Asn/c.303A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),1619,42,1672,"0,0251196172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,34",Neutral,74,Tolerated,"28,27","14,69"
"low bq, low freq, many artifacts",UPN2_081,17,7579384,T,G,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys101Asn/c.303A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),3398,65,3490,"0,0186246418",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,34",Neutral,74,Tolerated,"28,43","14,22"
"low bq, bad alignment, many samples",UPN2_061,17,7579397,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val97Gly/c.290T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1094,25,1135,"0,0220264317",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,51",Deleterious,0,Damaging,"24,82",15
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,17,7579397,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val97Gly/c.290T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),2165,49,2234,"0,0219337511",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,51",Deleterious,0,Damaging,"24,86","15,31"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,17,7579397,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val97Gly/c.290T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1364,20,1396,"0,0143266476",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,51",Deleterious,0,Damaging,"24,78","14,65"
"low bq, bad alignment, many samples",UPN2_064,17,7579397,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val97Gly/c.290T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),917,25,946,"0,0264270613",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,51",Deleterious,0,Damaging,"25,34","15,08"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,17,7579397,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val97Gly/c.290T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),2544,55,2616,"0,0210244648",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,51",Deleterious,0,Damaging,"24,83","14,47"
"low bq, bad alignment, many samples",UPN2_072,17,7579397,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val97Gly/c.290T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),2604,63,2690,"0,0234200743",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,51",Deleterious,0,Damaging,"24,9","15,22"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_075,17,7579397,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val97Gly/c.290T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1866,31,1910,"0,0162303665",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,51",Deleterious,0,Damaging,"25,66","15,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,17,7579397,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val97Gly/c.290T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1315,21,1351,"0,0155440415",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,51",Deleterious,0,Damaging,"24,66","14,95"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,17,7579397,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val97Gly/c.290T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1733,32,1773,"0,0180485054",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,51",Deleterious,0,Damaging,"24,57","15,59"
"low bq, bad alignment, low freq, many artifacts",UPN2_081,17,7579397,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val97Gly/c.290T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),3575,75,3676,"0,0204026115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,51",Deleterious,0,Damaging,"24,99","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_041,17,7579398,C,A,missense_variant(MODERATE|MISSENSE|Gtc/Ttc|p.Val97Phe/c.289G>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),12317,183,12567,"0,014561948",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,13",Deleterious,0,Damaging,"28,38","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_042,17,7579398,C,A,missense_variant(MODERATE|MISSENSE|Gtc/Ttc|p.Val97Phe/c.289G>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),12328,170,12529,"0,013568521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,13",Deleterious,0,Damaging,"28,83","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_043,17,7579398,C,A,missense_variant(MODERATE|MISSENSE|Gtc/Ttc|p.Val97Phe/c.289G>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),7273,92,7387,"0,0124543116",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,13",Deleterious,0,Damaging,"28,63","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_044,17,7579398,C,A,missense_variant(MODERATE|MISSENSE|Gtc/Ttc|p.Val97Phe/c.289G>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),1934,30,1970,"0,0152284264",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,13",Deleterious,0,Damaging,"27,94","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_045,17,7579398,C,A,missense_variant(MODERATE|MISSENSE|Gtc/Ttc|p.Val97Phe/c.289G>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),5519,82,5624,"0,0145803698",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,13",Deleterious,0,Damaging,"27,9","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_046,17,7579398,C,A,missense_variant(MODERATE|MISSENSE|Gtc/Ttc|p.Val97Phe/c.289G>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),13384,152,13581,"0,0111921066",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,13",Deleterious,0,Damaging,"28,84","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_047,17,7579398,C,A,missense_variant(MODERATE|MISSENSE|Gtc/Ttc|p.Val97Phe/c.289G>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),13868,188,14108,"0,0133257726",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,13",Deleterious,0,Damaging,"28,7","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_048,17,7579398,C,A,missense_variant(MODERATE|MISSENSE|Gtc/Ttc|p.Val97Phe/c.289G>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),12997,192,13223,"0,0145201543",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,13",Deleterious,0,Damaging,"28,72","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_049,17,7579398,C,A,missense_variant(MODERATE|MISSENSE|Gtc/Ttc|p.Val97Phe/c.289G>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),7779,129,7931,"0,0162652881",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,13",Deleterious,0,Damaging,"27,91","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_050,17,7579398,C,A,missense_variant(MODERATE|MISSENSE|Gtc/Ttc|p.Val97Phe/c.289G>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),7697,112,7838,"0,0142893595",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,13",Deleterious,0,Damaging,"28,49","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_051,17,7579398,C,A,missense_variant(MODERATE|MISSENSE|Gtc/Ttc|p.Val97Phe/c.289G>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),10431,135,10593,"0,0127442651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,13",Deleterious,0,Damaging,"28,43","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_052,17,7579398,C,A,missense_variant(MODERATE|MISSENSE|Gtc/Ttc|p.Val97Phe/c.289G>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),5990,67,6086,"0,0110088728",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,13",Deleterious,0,Damaging,"28,6","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_053,17,7579398,C,A,missense_variant(MODERATE|MISSENSE|Gtc/Ttc|p.Val97Phe/c.289G>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),11414,148,11598,"0,0127608208",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,13",Deleterious,0,Damaging,"28,47","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_054,17,7579398,C,A,missense_variant(MODERATE|MISSENSE|Gtc/Ttc|p.Val97Phe/c.289G>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),8123,116,8263,"0,0140384848",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,13",Deleterious,0,Damaging,"28,89","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_055,17,7579398,C,A,missense_variant(MODERATE|MISSENSE|Gtc/Ttc|p.Val97Phe/c.289G>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),12025,151,12205,"0,0123719787",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,13",Deleterious,0,Damaging,"28,83","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_056,17,7579398,C,A,missense_variant(MODERATE|MISSENSE|Gtc/Ttc|p.Val97Phe/c.289G>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),7622,91,7740,"0,0117571059",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,13",Deleterious,0,Damaging,"28,82","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_057,17,7579398,C,A,missense_variant(MODERATE|MISSENSE|Gtc/Ttc|p.Val97Phe/c.289G>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),6602,106,6719,"0,0157761572",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,13",Deleterious,0,Damaging,"28,4","14,32"
"low bq, low freq, many artifacts",UPN2_058,17,7579398,C,A,missense_variant(MODERATE|MISSENSE|Gtc/Ttc|p.Val97Phe/c.289G>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),13754,178,13980,"0,012732475",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,13",Deleterious,0,Damaging,"28,62","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_061,17,7579401,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser96Ala/c.286T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),2085,31,2125,"0,0145882353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,41",Neutral,729,Tolerated,"28,98","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_062,17,7579401,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser96Ala/c.286T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),4077,44,4150,"0,0106024096",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,41",Neutral,729,Tolerated,29,"14,5"
"low bq, low freq, many artifacts, many samples",UPN2_063,17,7579401,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser96Ala/c.286T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),2417,35,2464,"0,0142045455",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,41",Neutral,729,Tolerated,"28,09",14
"low bq, low freq, many artifacts, many samples",UPN2_064,17,7579401,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser96Ala/c.286T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1694,21,1730,"0,0121387283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,41",Neutral,729,Tolerated,"28,52","16,52"
"low bq, low freq, many artifacts, many samples",UPN2_071,17,7579401,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser96Ala/c.286T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),4571,86,4683,"0,0183642964",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,41",Neutral,729,Tolerated,"28,87","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_072,17,7579401,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser96Ala/c.286T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),4748,73,4841,"0,015079529",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,41",Neutral,729,Tolerated,"28,58","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_075,17,7579401,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser96Ala/c.286T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),3458,43,3525,"0,0121985816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,41",Neutral,729,Tolerated,"28,99","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_076,17,7579401,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser96Ala/c.286T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1732,20,1756,"0,0113895216",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,41",Neutral,729,Tolerated,"28,42","16,8"
"low bq, low freq, many artifacts, many samples",UPN2_078,17,7579401,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser96Ala/c.286T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),2479,35,2529,"0,0138394622",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,41",Neutral,729,Tolerated,"28,72","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_080,17,7579401,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser96Ala/c.286T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),3186,55,3254,"0,0169022741",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,41",Neutral,729,Tolerated,"28,9","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_081,17,7579401,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser96Ala/c.286T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),6630,99,6783,"0,0145953118",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,41",Neutral,729,Tolerated,"28,98","14,72"
"low bq, low freq, many artifacts",UPN2_084,17,7579401,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser96Ala/c.286T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1780,24,1812,"0,0132450331",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,41",Neutral,729,Tolerated,"28,9","16,12"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_060,17,7579404,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser95Ala/c.283T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1650,23,1689,"0,0136175252",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,48",Neutral,28,Damaging,"26,49",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,17,7579404,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser95Ala/c.283T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),2069,45,2137,"0,0210575573",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,48",Neutral,28,Damaging,"26,74","15,96"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,17,7579404,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser95Ala/c.283T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),4059,81,4173,"0,019410496",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,48",Neutral,28,Damaging,"26,88","14,58"
"low bq, bad alignment, many samples",UPN2_063,17,7579404,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser95Ala/c.283T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),2366,61,2492,"0,0244783307",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,48",Neutral,28,Damaging,"24,89","14,33"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,17,7579404,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser95Ala/c.283T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1694,29,1743,"0,0166379805",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,48",Neutral,28,Damaging,"26,07","14,24"
"low bq, bad alignment, many samples",UPN2_068,17,7579404,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser95Ala/c.283T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),708,22,743,"0,0296096904",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,48",Neutral,28,Damaging,"25,59",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,17,7579404,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser95Ala/c.283T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),4552,93,4714,"0,0197284684",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,48",Neutral,28,Damaging,"26,2","14,63"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,17,7579404,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser95Ala/c.283T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),4732,76,4873,"0,015596142",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,48",Neutral,28,Damaging,"26,06","15,17"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,17,7579404,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser95Ala/c.283T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1299,25,1342,"0,0186289121",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,48",Neutral,28,Damaging,"26,78","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_075,17,7579404,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser95Ala/c.283T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),3467,47,3544,"0,013261851",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,48",Neutral,28,Damaging,"27,38","15,13"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,17,7579404,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser95Ala/c.283T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1718,29,1768,"0,0164027149",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,48",Neutral,28,Damaging,"25,85","14,24"
"low bq, bad alignment, many samples",UPN2_078,17,7579404,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser95Ala/c.283T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),2450,62,2537,"0,024438313",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,48",Neutral,28,Damaging,"26,88","15,98"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_079,17,7579404,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser95Ala/c.283T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1368,22,1402,"0,0156918688",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,48",Neutral,28,Damaging,"26,92","16,64"
"low bq, low freq, many artifacts, many samples",UPN2_080,17,7579404,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser95Ala/c.283T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),3164,55,3268,"0,0168298654",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,48",Neutral,28,Damaging,"27,09","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_081,17,7579404,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser95Ala/c.283T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),6657,111,6812,"0,0162947739",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,48",Neutral,28,Damaging,"27,26","14,77"
"low bq, bad alignment, many samples",UPN2_082,17,7579404,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser95Ala/c.283T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),939,22,971,"0,0226570546",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,48",Neutral,28,Damaging,"26,59",15
"low bq, bad alignment, many samples",UPN2_083,17,7579404,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser95Ala/c.283T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1820,44,1891,"0,0232681121",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,48",Neutral,28,Damaging,"25,83","14,86"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,17,7579404,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser95Ala/c.283T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1761,36,1815,"0,0198347107",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,48",Neutral,28,Damaging,"26,73","14,75"
"low bq, bad alignment",UPN2_087,17,7579404,A,C,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser95Ala/c.283T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),974,29,1020,"0,0284313725",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,48",Neutral,28,Damaging,"26,27","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_018,17,7579404,A,T,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser95Thr/c.283T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),5236,58,5321,"0,0109002067",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,125,Tolerated,"29,2",15
"low bq, low freq, many artifacts, many samples",UPN2_041,17,7579404,A,T,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser95Thr/c.283T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),12607,139,12809,"0,0108517449",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,125,Tolerated,"29,16","16,24"
"low bq, low freq, many artifacts, many samples",UPN2_044,17,7579404,A,T,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser95Thr/c.283T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),1965,35,2014,"0,0173783515",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,125,Tolerated,"27,71","15,51"
"low bq, low freq, many artifacts, many samples",UPN2_045,17,7579404,A,T,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser95Thr/c.283T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),5652,107,5792,"0,0184737569",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,125,Tolerated,"28,08","15,99"
"low bq, low freq, many artifacts, many samples",UPN2_049,17,7579404,A,T,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser95Thr/c.283T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),7945,167,8156,"0,0204757234",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,125,Tolerated,"27,81","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_050,17,7579404,A,T,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser95Thr/c.283T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),7833,91,7980,"0,0114035088",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,125,Tolerated,"29,17","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_051,17,7579404,A,T,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser95Thr/c.283T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),10633,121,10811,"0,0111923041",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,125,Tolerated,"29,17","15,49"
"low bq, low freq, many artifacts, many samples",UPN2_053,17,7579404,A,T,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser95Thr/c.283T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),11623,139,11849,"0,0117309478",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,125,Tolerated,"29,07","15,52"
"low bq, low freq, many artifacts, many samples",UPN2_057,17,7579404,A,T,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser95Thr/c.283T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),6687,88,6823,"0,0128975524",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,125,Tolerated,"29,35","15,68"
"low bq, low freq, many artifacts, many samples",UPN2_040,17,7579404,A,T,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser95Thr/c.283T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),10927,127,11096,"0,011445566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,125,Tolerated,"28,96","16,14"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,17,7579404,A,T,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser95Thr/c.283T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),2366,48,2492,"0,0192616372",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,125,Tolerated,"24,89","15,29"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,17,7579404,A,T,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser95Thr/c.283T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),4552,62,4714,"0,0131523123",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,125,Tolerated,"26,2","15,5"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,17,7579404,A,T,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser95Thr/c.283T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),4732,61,4873,"0,0125179561",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,125,Tolerated,"26,06","16,34"
"low bq, bad alignment, low freq, many artifacts",UPN2_083,17,7579404,A,T,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser95Thr/c.283T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),1820,20,1891,"0,0105764146",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,125,Tolerated,"25,83",14
"low bq, low freq, many artifacts, many samples",UPN2_001,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),3630,37,3688,"0,010032538",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"27,78","14,49"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_017,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),2578,41,2646,"0,0154950869",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"25,54","16,17"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_018,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),5245,60,5329,"0,0112591481",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"26,1",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_002,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),3291,60,3378,"0,0177619893",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"26,25","15,08"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_041,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),12526,173,12855,"0,0134577985",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"26,49","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_089,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),5202,75,5307,"0,0141322781",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"27,29",15
"low bq, low freq, many artifacts, many samples",UPN2_042,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),12469,142,12746,"0,01114075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"27,02","14,91"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_044,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1964,44,2027,"0,0217069561",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"24,92",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_030,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),7470,100,7622,"0,013119916",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"25,78","14,31"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_031,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),5230,63,5326,"0,0118287646",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"26,15","14,78"
"low bq, bad alignment, many samples",UPN2_045,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),5629,145,5819,"0,0249183709",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"25,42","14,44"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_033,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),5287,60,5416,"0,0110782866",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"26,57","15,03"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_034,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),2023,29,2066,"0,0140367861",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"25,7","14,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),14007,177,14328,"0,0123534338",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"26,87","14,59"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_048,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),13126,141,13404,"0,010519248",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"26,8","14,7"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_036,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),23959,291,24470,"0,0118921128",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"26,25","15,49"
"low bq, low freq, many artifacts, many samples",UPN2_006,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),3688,53,3773,"0,0140471773",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"27,09","14,58"
"low bq, bad alignment, many samples",UPN2_049,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),7923,189,8202,"0,0230431602",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"25,33","14,44"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),7841,101,8010,"0,0126092385",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"26,33","14,81"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),10572,152,10845,"0,0140156754",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"26,33","15,16"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_039,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),24278,350,24855,"0,0140816737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"25,55","14,44"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),11573,197,11884,"0,0165769101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"26,21","14,44"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),8211,95,8399,"0,0113108703",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"26,87","14,14"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_008,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),13384,144,13628,"0,0105664808",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"26,94","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_010,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),7589,95,7766,"0,0122328097",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"27,12","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_011,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),7181,80,7311,"0,0109424155",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"27,38","14,57"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),12162,125,12406,"0,0100757698",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"26,9","14,52"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),7718,101,7889,"0,0128026366",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"26,71","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_090,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),3218,47,3294,"0,0142683667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"28,3","14,68"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),6689,85,6845,"0,0124178232",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"26,48","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_058,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),13907,166,14213,"0,0116794484",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"27,17","14,58"
"low bq, bad alignment, many samples",UPN2_059,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),818,44,871,"0,0505166475",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"24,58","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_012,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),4677,55,4768,"0,0115352349",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"27,4","14,25"
"low bq, bad alignment, many samples",UPN2_060,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1601,79,1694,"0,046635183",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"23,78","15,68"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_040,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),10869,155,11119,"0,0139401025",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"25,84","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_091,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),5057,58,5138,"0,0112884391",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"28,15","14,12"
"low bq, low freq, many artifacts, many samples",UPN2_092,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),3057,49,3121,"0,0157000961",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"28,32","16,94"
"low bq, low freq, many artifacts, many samples",UPN2_093,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),4341,48,4419,"0,010862186",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"28,29","15,12"
"low bq, bad alignment, many samples",UPN2_061,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1996,120,2139,"0,0561009818",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"24,68","14,8"
"low bq, bad alignment, many samples",UPN2_062,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),3919,235,4186,"0,0561395127",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"24,32","15,01"
"low bq, bad alignment, many samples",UPN2_063,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),2324,166,2502,"0,0663469225",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"22,97","14,66"
"low bq, bad alignment, many samples",UPN2_064,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1627,105,1746,"0,060137457",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"23,85","15,03"
"low bq, bad alignment, many samples",UPN2_065,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),343,20,367,"0,0544959128",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"24,64","14,65"
"low bq, bad alignment, many samples",UPN2_068,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),692,44,745,"0,0590604027",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"23,14","14,75"
"low bq, bad alignment, many samples",UPN2_069,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1123,58,1192,"0,0486577181",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"24,48","14,67"
"low bq, bad alignment, many samples",UPN2_070,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),903,46,956,"0,0481171548",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"24,95","14,96"
"low bq, bad alignment, many samples",UPN2_071,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),4436,267,4731,"0,0564362714",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"24,38","15,04"
"low bq, bad alignment, many samples",UPN2_072,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),4577,275,4887,"0,0562717414",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"24,35","15,27"
"low bq, bad alignment, many samples",UPN2_073,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1284,52,1345,"0,03866171",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"24,26","15,37"
"low bq, bad alignment, many samples",UPN2_075,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),3339,181,3545,"0,0510578279",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"25,34","15,38"
"low bq, bad alignment, many samples",UPN2_076,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1641,112,1771,"0,0632411067",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"23,72","14,95"
"low bq, bad alignment, many samples",UPN2_077,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),836,49,888,"0,0551801802",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"24,88","14,98"
"low bq, bad alignment, many samples",UPN2_078,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),2378,136,2541,"0,0535222353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"24,61","15,44"
"low bq, bad alignment, many samples",UPN2_079,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1328,60,1405,"0,0427046263",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"25,12","14,65"
"low bq, bad alignment, many samples",UPN2_080,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),3072,171,3270,"0,052293578",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"25,24","15,6"
"low bq, bad alignment, many samples",UPN2_081,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),6476,293,6820,"0,0429618768",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"25,08","15,49"
"low bq, bad alignment, many samples",UPN2_082,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),920,48,973,"0,049331963",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"24,41","15,19"
"low bq, bad alignment, many samples",UPN2_083,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1766,110,1900,"0,0578947368",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"23,58","15,37"
"low bq, bad alignment, many samples",UPN2_084,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1712,90,1818,"0,0495049505",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"24,81","15,34"
"low bq, bad alignment, many samples",UPN2_085,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),647,32,686,"0,0466472303",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"23,79","16,88"
"low bq, bad alignment, many samples",UPN2_087,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),961,57,1023,"0,0557184751",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"24,16","14,89"
"low bq, bad alignment, many samples",UPN2_088,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),750,45,802,"0,0561097257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"24,58","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_094,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),4315,65,4404,"0,0147593097",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"27,29","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_095,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),6246,71,6352,"0,0111775819",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"28,15","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_098,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),4947,57,5050,"0,0112871287",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"28,25","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_099,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),2738,29,2787,"0,0104054539",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"28,21","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_100,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),5250,78,5351,"0,0145767146",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"27,34","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_101,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),4565,77,4682,"0,0164459633",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"27,16","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_102,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),5072,53,5143,"0,0103052693",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"27,94","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_103,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),5972,88,6087,"0,0144570396",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"28,03","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_104,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),5352,60,5442,"0,0110253583",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"28,15","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_105,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),4164,45,4236,"0,0106232295",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"28,07","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_106,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),5555,83,5679,"0,0146152492",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"27,47","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_107,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),6431,102,6566,"0,015534572",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"27,41","14,2"
"low bq, low freq, many artifacts, many samples",UPN2_108,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),8708,110,8861,"0,0124139488",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"28,54","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_109,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),7434,91,7567,"0,0120259019",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"28,09","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_110,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),5604,102,5741,"0,0177669396",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"27,31","14,59"
"low bq, low freq, many artifacts",UPN2_111,17,7579407,A,C,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser94Ala/c.280T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),5736,127,5900,"0,0215254237",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,51,Tolerated,"27,3","15,74"
"low bq, low freq, many artifacts, many samples",UPN2_016,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),4924,82,5225,"0,0156937799",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"27,88","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_017,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),2523,46,2654,"0,0173323286",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"27,74","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_018,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),5065,100,5339,"0,0187300993",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"27,67","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_002,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),3224,61,3388,"0,0180047226",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"27,46",14
"low bq, low freq, many artifacts, many samples",UPN2_041,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),12204,171,12890,"0,0132660978",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"28,13","14,56"
"low bq, bad alignment, many samples",UPN2_044,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1887,45,2037,"0,0220913108",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"26,79",14
"low bq, low freq, many artifacts, many samples",UPN2_030,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),7237,157,7636,"0,0205605029",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"27,6","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_031,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),5081,76,5338,"0,0142375422",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"27,86","14,09"
"low bq, bad alignment, many samples",UPN2_045,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),5389,137,5851,"0,0234148009",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"26,83","14,19"
"low bq, low freq, many artifacts, many samples",UPN2_033,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),5160,80,5428,"0,0147383935",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"27,74","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_034,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1965,40,2070,"0,0193236715",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"27,81",14
"low bq, low freq, many artifacts, many samples",UPN2_036,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),23263,416,24531,"0,0169581346",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"27,78","14,46"
"low bq, bad alignment, many samples",UPN2_049,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),7594,202,8240,"0,0245145631",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"26,95","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_050,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),7614,123,8043,"0,0152928012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"28,04","14,11"
"low bq, low freq, many artifacts, many samples",UPN2_051,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),10258,164,10884,"0,0150679897",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"28,02","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_039,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),23599,496,24922,"0,0199020945",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"27,34","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_053,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),11263,162,11922,"0,0135883241",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"27,9","14,12"
"low bq, low freq, many artifacts, many samples",UPN2_010,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),7571,82,7786,"0,0105317236",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"28,53","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_057,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),6516,97,6871,"0,0141173046",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"28,17","14,76"
"low bq, many samples",UPN2_059,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),833,20,874,"0,0228832952",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"27,19",14
"low bq, low freq, many artifacts, many samples",UPN2_012,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),4644,54,4776,"0,0113065327",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"28,72","14,24"
"low bq, bad alignment, many samples",UPN2_060,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1594,46,1696,"0,0271226415",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"26,53","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_040,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),10508,219,11149,"0,0196430173",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"27,47","14,08"
"low bq, low freq, many artifacts, many samples",UPN2_061,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),2061,46,2148,"0,02141527",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"27,26","14,48"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),4038,69,4194,"0,0164520744",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"26,91","15,55"
"low bq, bad alignment, many samples",UPN2_064,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1635,52,1752,"0,0296803653",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"26,2","14,6"
"low bq, bad alignment, many samples",UPN2_068,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),699,25,748,"0,0334224599",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"26,17",14
"low bq, bad alignment, many samples",UPN2_069,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1128,35,1194,"0,0293132328",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"26,72","14,37"
"low bq, bad alignment, many samples",UPN2_071,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),4471,141,4753,"0,0296654744",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"26,43","14,51"
"low bq, bad alignment, many samples",UPN2_072,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),4617,116,4906,"0,0236445169",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"26,56","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_073,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1288,23,1346,"0,0170876672",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"27,48",14
"low bq, low freq, many artifacts, many samples",UPN2_075,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),3428,62,3556,"0,0174353206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"27,68","14,77"
"low bq, bad alignment, many samples",UPN2_076,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1665,45,1777,"0,0253235791",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"26,35",14
"low freq, many artifacts, many samples",UPN2_078,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),2431,39,2551,"0,0152881223",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,27,"14,79"
"low bq, low freq, many artifacts, many samples",UPN2_079,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1358,21,1411,"0,0148830617",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"27,38","15,71"
"low bq, low freq, many artifacts, many samples",UPN2_080,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),3145,40,3279,"0,0121988411",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"27,22",14
"low bq, low freq, many artifacts, many samples",UPN2_081,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),6616,72,6834,"0,0105355575",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"27,63","14,67"
"low bq, bad alignment, many samples",UPN2_082,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),921,28,978,"0,0286298569",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"26,61",14
"low bq, low freq, many artifacts, many samples",UPN2_084,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1743,28,1820,"0,0153846154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"27,32","15,11"
"low bq, bad alignment, many samples",UPN2_085,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),647,21,688,"0,0305232558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"26,1","14,33"
"low bq, many samples",UPN2_087,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),962,25,1027,"0,0243427459",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"27,09","14,52"
"low bq, bad alignment, many samples",UPN2_088,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),742,34,808,"0,0420792079",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"26,9",14
"low bq, low freq, many artifacts, many samples",UPN2_101,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),4523,50,4692,"0,0106564365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"28,41","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_107,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),6338,76,6574,"0,0115606936",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"28,47","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_110,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),5558,61,5753,"0,0106031636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"28,42","14,57"
"low bq, low freq, many artifacts",UPN2_111,17,7579409,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu93Arg/c.278T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),5706,71,5907,"0,0120196377",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,13,Damaging,"28,3",14
"low bq, low freq, many artifacts, many samples",UPN2_001,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),3575,80,3690,"0,0216802168",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"28,7","15,59"
"low bq, low freq, many artifacts, many samples",UPN2_014,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),6556,129,6760,"0,0190828402",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"28,67","16,15"
"low bq, low freq, many artifacts, many samples",UPN2_015,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),10245,199,10571,"0,0188250875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"28,65","16,14"
"low bq, low freq, many artifacts, many samples",UPN2_019,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),5783,81,5928,"0,0136639676",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"28,35","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_020,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),3957,89,4081,"0,0218083803",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"28,8","16,72"
"low bq, low freq, many artifacts, many samples",UPN2_021,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),5800,123,5983,"0,0205582484",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"28,55","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_022,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),7167,104,7344,"0,01416122",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"28,71","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_023,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),6782,143,6988,"0,020463652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"28,64","15,97"
"low bq, low freq, many artifacts, many samples",UPN2_024,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),3030,67,3137,"0,0213579853",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"28,07","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_025,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),10015,163,10294,"0,0158344667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"28,75","16,2"
"low bq, low freq, many artifacts, many samples",UPN2_026,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),8488,132,8731,"0,0151185431",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"28,41","15,39"
"low bq, low freq, many artifacts, many samples",UPN2_027,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),8868,170,9136,"0,0186077058",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"28,58","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_089,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),5162,88,5320,"0,0165413534",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"28,38","15,58"
"low bq, many samples",UPN2_042,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),12313,316,12776,"0,024733876",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"28,77","16,68"
"low bq, low freq, many artifacts, many samples",UPN2_028,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),7275,116,7470,"0,0155287818",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"28,47","14,63"
"low bq, many samples",UPN2_043,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),7272,181,7526,"0,0240499601",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"28,79","16,28"
"low bq, many samples",UPN2_029,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),7066,186,7336,"0,0253544166",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"28,59","17,15"
"low bq, low freq, many artifacts, many samples",UPN2_005,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),1320,29,1365,"0,0212454212",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"28,35","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_032,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),2530,50,2606,"0,0191864927",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"28,66","15,64"
"low bq, many samples",UPN2_046,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),13405,322,13860,"0,0232323232",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"28,73","16,05"
"low bq, many samples",UPN2_047,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),13782,378,14352,"0,0263377926",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"28,62","15,62"
"low bq, many samples",UPN2_048,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),12974,322,13431,"0,0239743876",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"28,68","15,69"
"low bq, low freq, many artifacts, many samples",UPN2_035,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),13050,272,13459,"0,0202095252",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"28,68","15,84"
"low bq, low freq, many artifacts, many samples",UPN2_006,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),3665,65,3777,"0,0172094255",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"28,26","16,31"
"low bq, low freq, many artifacts, many samples",UPN2_037,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),11749,235,12096,"0,0194279101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"28,58","16,57"
"low bq, many samples",UPN2_052,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),5980,162,6200,"0,0261290323",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"28,55","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_038,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),13198,255,13588,"0,0187665587",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"28,61","15,71"
"low bq, many samples",UPN2_054,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),8069,220,8409,"0,026162445",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"28,57","15,82"
"low bq, low freq, many artifacts, many samples",UPN2_007,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),9305,159,9552,"0,0166457286",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"28,8","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_008,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),13261,217,13655,"0,0158916148",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"28,54","15,42"
"low bq, low freq, many artifacts, many samples",UPN2_009,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),10742,171,11047,"0,0154793157",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"28,68","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_011,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),7087,135,7322,"0,0184375854",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"28,7","15,2"
"low bq, many samples",UPN2_055,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),12002,278,12424,"0,0223760464",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"28,65","16,12"
"low bq, many samples",UPN2_056,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),7586,223,7911,"0,0281885982",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"28,1","15,64"
"low bq, low freq, many artifacts, many samples",UPN2_090,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),3234,39,3296,"0,0118325243",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"29,56","15,82"
"low bq, many samples",UPN2_058,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),13753,367,14249,"0,0257561934",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"28,83","15,69"
"low bq, low freq, many artifacts, many samples",UPN2_013,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),2439,40,2503,"0,015980823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"28,96","15,75"
"low bq, low freq, many artifacts, many samples",UPN2_091,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),5038,54,5139,"0,0105078809",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"29,67","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_092,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),3056,34,3126,"0,0108765195",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"29,28","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_093,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),4333,47,4421,"0,0106310789",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"29,87",14
"low bq, low freq, many artifacts, many samples",UPN2_094,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),4285,78,4412,"0,0176790571",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"28,63","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_095,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),6228,72,6358,"0,0113243158",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"29,75","18,07"
"low bq, low freq, many artifacts, many samples",UPN2_096,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),4692,57,4785,"0,0119122257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"29,8","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_097,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),5168,70,5295,"0,0132200189",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"29,58","16,01"
"low bq, low freq, many artifacts, many samples",UPN2_098,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),4958,60,5055,"0,0118694362",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"29,62","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_100,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),5196,90,5357,"0,016800448",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"28,35","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_102,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),5020,77,5148,"0,014957265",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"29,33","16,23"
"low bq, low freq, many artifacts, many samples",UPN2_103,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),5964,65,6094,"0,0106662291",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"29,68","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_105,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),4148,56,4240,"0,0132075472",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"29,46","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_106,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),5528,95,5683,"0,016716523",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"28,53","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_108,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),8692,118,8872,"0,0133002705",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"29,8","16,8"
"low bq, low freq, many artifacts",UPN2_109,17,7579409,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu93Gln/c.278T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),7430,80,7579,"0,0105554823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,25",Neutral,19,Damaging,"29,53","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_076,17,7579415,C,G,missense_variant(MODERATE|MISSENSE|tGg/tCg|p.Trp91Ser/c.272G>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),1766,21,1792,"0,01171875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,86",Neutral,565,Tolerated,"28,25",14
"low bq, low freq, many artifacts, many samples",UPN2_078,17,7579415,C,G,missense_variant(MODERATE|MISSENSE|tGg/tCg|p.Trp91Ser/c.272G>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),2526,26,2556,"0,010172144",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,86",Neutral,565,Tolerated,"28,47","14,5"
"low bq, low freq, many artifacts",UPN2_002,17,7579415,C,T,stop_gained(HIGH|NONSENSE|tGg/tAg|p.Trp91*/c.272G>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),3343,47,3399,"0,0138275964",0,0,0,0,1,0,0,1,2,NO,NO,"COSM323933, COSM3378448, COSM3378447, COSM44192, COSM323934","kidney, large_intestine, lung, pancreas, skin, upper_aerodigestive_tract, central_nervous_system, urinary_tract","10, 10, 4, 10, 15, 6, 1, 1",NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,97","26,19"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,17,7579416,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp91Gly/c.271T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),5489,66,5910,"0,0111675127",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,"0,14",Tolerated,"26,98","18,76"
"low bq, low freq, many artifacts, many samples",UPN2_060,17,7579416,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp91Gly/c.271T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1642,23,1708,"0,0134660422",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,"0,14",Tolerated,"27,38","14,78"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,17,7579416,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp91Gly/c.271T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),2408,55,2553,"0,0215432824",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,"0,14",Tolerated,"25,35","14,8"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,17,7579416,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp91Gly/c.271T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1665,26,1765,"0,0147308782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,"0,14",Tolerated,"26,58",14
"low bq, low freq, many artifacts, many samples",UPN2_071,17,7579416,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp91Gly/c.271T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),4593,54,4797,"0,0112570356",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,"0,14",Tolerated,"27,01","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_075,17,7579416,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp91Gly/c.271T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),3477,37,3569,"0,0103670496",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,"0,14",Tolerated,"28,44","16,24"
"low bq, bad alignment, low freq, many artifacts",UPN2_083,17,7579416,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp91Gly/c.271T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1846,27,1926,"0,0140186916",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,"0,14",Tolerated,"26,3",14
"low freq, many artifacts",UPN2_024,17,7579416,A,G,missense_variant(MODERATE|MISSENSE|Tgg/Cgg|p.Trp91Arg/c.271T>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),3039,35,3145,"0,0111287758",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,"0,148",Tolerated,"29,02","32,97"
"low freq, many artifacts",UPN2_064,17,7579416,A,G,missense_variant(MODERATE|MISSENSE|Tgg/Cgg|p.Trp91Arg/c.271T>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),1665,24,1765,"0,0135977337",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"26,58","32,12"
"low bq, low freq, many artifacts, many samples",UPN2_001,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),3617,74,3700,"0,02",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"29,74","16,5"
"low bq, low freq, many artifacts, many samples",UPN2_014,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),6638,113,6773,"0,0166838919",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"29,32","15,59"
"low bq, low freq, many artifacts, many samples",UPN2_015,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),10381,176,10603,"0,0165990757",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"28,98","16,84"
"low bq, many samples",UPN2_016,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),5020,203,5255,"0,0386298763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"28,03","15,38"
"low bq, many samples",UPN2_017,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),2558,92,2668,"0,0344827586",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"27,91","15,47"
"low bq, many samples",UPN2_018,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),5164,165,5365,"0,0307548928",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"27,78","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_019,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),5814,103,5940,"0,0173400673",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"28,93","16,94"
"low bq, low freq, many artifacts, many samples",UPN2_020,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),4011,62,4089,"0,0151626315",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"29,16","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_021,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),5855,105,5993,"0,0175204405",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"29,16","16,34"
"low bq, many samples",UPN2_002,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),3288,85,3399,"0,0250073551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"27,99","15,51"
"low bq, low freq, many artifacts, many samples",UPN2_022,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),7213,114,7359,"0,0154912352",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"29,28","15,55"
"low bq, low freq, many artifacts, many samples",UPN2_023,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),6860,111,7006,"0,0158435627",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"29,31","16,68"
"low bq, many samples",UPN2_041,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),12449,427,12981,"0,03289423",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"28,39","15,81"
"low bq, low freq, many artifacts, many samples",UPN2_025,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),10116,153,10320,"0,0148255814",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"29,45","15,61"
"low bq, low freq, many artifacts, many samples",UPN2_026,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),8590,129,8748,"0,0147462277",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"29,08","16,29"
"low bq, low freq, many artifacts, many samples",UPN2_027,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),8971,140,9161,"0,0152821744",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"29,25","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_089,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),5189,92,5336,"0,0172413793",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"29,38","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_042,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),12467,280,12832,"0,0218204489",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"29,31","16,01"
"low bq, low freq, many artifacts, many samples",UPN2_028,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),7312,141,7490,"0,0188251001",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"29,02","16,63"
"low bq, many samples",UPN2_043,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),7366,170,7570,"0,0224570674",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"29,4","16,11"
"low bq, low freq, many artifacts, many samples",UPN2_029,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),7170,128,7354,"0,0174054936",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"29,08","14,9"
"low bq, many samples",UPN2_030,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),7357,245,7665,"0,0319634703",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"27,95","15,22"
"low bq, many samples",UPN2_031,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),5168,164,5362,"0,0305856024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"28,01","14,82"
"low bq, many samples",UPN2_005,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),1330,36,1368,"0,0263157895",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"29,39","20,75"
"low bq, low freq, many artifacts, many samples",UPN2_032,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),2539,54,2612,"0,0206738132",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"29,31","16,46"
"low bq, low freq, many artifacts, many samples",UPN2_046,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),13534,284,13908,"0,0204199022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"29,34","15,85"
"low bq, many samples",UPN2_033,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),5245,191,5463,"0,0349624748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"28,1","15,84"
"low bq, many samples",UPN2_034,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),1997,61,2074,"0,0294117647",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"27,85","14,79"
"low bq, many samples",UPN2_047,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),14001,328,14416,"0,0227524972",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"29,17","15,95"
"low bq, low freq, many artifacts, many samples",UPN2_048,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),13083,294,13480,"0,021810089",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"29,26","16,57"
"low bq, low freq, many artifacts, many samples",UPN2_035,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),13200,245,13495,"0,0181548722",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"29,24","15,34"
"low bq, many samples",UPN2_036,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),23696,809,24668,"0,0327955246",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"27,96","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_006,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),3705,60,3788,"0,0158394931",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"29,24","14,85"
"low bq, many samples",UPN2_049,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),7792,445,8331,"0,0534149562",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"27,02","15,04"
"low bq, many samples",UPN2_050,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),7727,316,8105,"0,0389882788",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"28,27","16,25"
"low bq, low freq, many artifacts, many samples",UPN2_037,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),11857,209,12129,"0,0172314288",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"29,07","15,88"
"low bq, many samples",UPN2_051,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),10456,411,10968,"0,0374726477",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"28,44","15,74"
"low bq, many samples",UPN2_052,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),6033,145,6220,"0,0233118971",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"29,07","16,1"
"low bq, low freq, many artifacts, many samples",UPN2_038,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),13318,244,13613,"0,0179240432",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"29,19","15,97"
"low bq, many samples",UPN2_039,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),23962,886,25050,"0,0353692615",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"27,59","15,47"
"low bq, many samples",UPN2_053,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),11439,464,11997,"0,0386763358",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"28,26","15,58"
"low bq, many samples",UPN2_054,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),8184,201,8446,"0,0237982477",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"29,06","16,36"
"low bq, low freq, many artifacts, many samples",UPN2_007,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),9397,142,9577,"0,0148271901",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"29,57","16,3"
"low bq, low freq, many artifacts, many samples",UPN2_008,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),13381,225,13694,"0,0164305535",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"29,41","16,03"
"low bq, low freq, many artifacts, many samples",UPN2_009,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),10854,164,11077,"0,0148054527",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"29,56","16,29"
"low bq, low freq, many artifacts, many samples",UPN2_010,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),7655,118,7809,"0,0151107696",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"29,3","16,11"
"low bq, low freq, many artifacts, many samples",UPN2_011,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),7143,135,7348,"0,0183723462",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"29,45","16,11"
"low bq, many samples",UPN2_055,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),12129,281,12479,"0,02251783",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"29,05","15,96"
"low bq, many samples",UPN2_056,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),7677,224,7952,"0,0281690141",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"28,72","17,07"
"low bq, low freq, many artifacts, many samples",UPN2_090,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),3252,35,3298,"0,0106124924",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"30,46","16,14"
"low bq, many samples",UPN2_057,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),6638,247,6925,"0,03566787",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"28,51","16,53"
"low bq, many samples",UPN2_058,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),13861,375,14307,"0,0262109457",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"29,36","18,05"
"low bq, low freq, many artifacts, many samples",UPN2_012,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),4690,78,4789,"0,0162873251",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"29,56","15,81"
"low bq, many samples",UPN2_040,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),10684,408,11208,"0,0364025696",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"27,6","15,31"
"low bq, low freq, many artifacts, many samples",UPN2_013,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),2477,27,2511,"0,0107526882",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"29,63","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_061,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),2101,28,2155,"0,0129930394",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"28,23","16,39"
"low bq, low freq, many artifacts, many samples",UPN2_062,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),4111,53,4208,"0,012595057",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"27,98","16,55"
"low bq, bad alignment, many samples",UPN2_068,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),718,25,756,"0,0330687831",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"26,5","14,88"
"low bq, many samples",UPN2_069,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),1157,32,1200,"0,0266666667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"27,04","14,91"
"low bq, many samples",UPN2_072,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),4744,130,4934,"0,0263477908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"27,31","14,82"
"low bq, many samples",UPN2_076,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),1707,55,1793,"0,0306748466",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"27,06","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_078,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),2477,38,2556,"0,0148669797",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"28,27","16,89"
"low bq, low freq, many artifacts, many samples",UPN2_079,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),1377,22,1413,"0,0155697098",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"28,73","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_080,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),3216,39,3289,"0,0118577075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"28,42","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_081,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),6711,86,6858,"0,0125400992",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"28,58","15,63"
"low bq, many samples",UPN2_082,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),942,29,988,"0,0293522267",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"27,82","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_084,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),1768,31,1826,"0,0169769989",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"28,16","14,42"
"low bq, many samples",UPN2_087,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),983,36,1038,"0,0346820809",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"27,36",15
"low bq, bad alignment, many samples",UPN2_088,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),778,25,812,"0,0307881773",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"26,88",14
"low bq, low freq, many artifacts, many samples",UPN2_094,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),4316,77,4422,"0,0174129353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"29,27","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_097,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),5206,63,5306,"0,0118733509",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"30,38","16,05"
"low bq, low freq, many artifacts, many samples",UPN2_100,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),5234,104,5377,"0,0193416403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"29,19","15,91"
"low bq, low freq, many artifacts, many samples",UPN2_101,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),4597,95,4717,"0,0201399194",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"29,17","15,42"
"low bq, low freq, many artifacts, many samples",UPN2_102,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),5079,56,5159,"0,0108548168",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"30,62","16,25"
"low bq, low freq, many artifacts, many samples",UPN2_104,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),5380,58,5459,"0,0106246565",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"30,63","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_105,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),4172,49,4253,"0,0115212791",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"30,42","16,24"
"low bq, low freq, many artifacts, many samples",UPN2_106,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),5570,99,5705,"0,0173531989",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"29,18","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_107,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),6429,124,6598,"0,0187935738",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"29,23","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_110,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),5624,109,5782,"0,0188516084",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"29,1","15,22"
"low bq, low freq, many artifacts",UPN2_111,17,7579416,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp91Arg/c.271T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),5765,111,5933,"0,0187089162",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,148,Tolerated,"29,04","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_030,17,7579419,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser90Ala/c.268T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),7407,94,7659,"0,0122731427",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,61,Tolerated,"28,59","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_039,17,7579419,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser90Ala/c.268T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),24188,270,25067,"0,0107711334",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,61,Tolerated,"28,38","15,21"
"low bq, many samples",UPN2_059,17,7579419,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser90Ala/c.268T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),846,20,879,"0,0227531286",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,61,Tolerated,"28,38",15
"low bq, low freq, many artifacts, many samples",UPN2_060,17,7579419,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser90Ala/c.268T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1649,31,1711,"0,0181180596",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,61,Tolerated,"27,69","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_040,17,7579419,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser90Ala/c.268T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),10805,121,11215,"0,0107891217",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,61,Tolerated,"28,46",14
"low bq, low freq, many artifacts, many samples",UPN2_061,17,7579419,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser90Ala/c.268T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),2090,37,2154,"0,0171773445",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,61,Tolerated,"28,51","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_062,17,7579419,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser90Ala/c.268T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),4106,66,4212,"0,0156695157",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,61,Tolerated,"28,27","14,47"
"low bq, bad alignment, many samples",UPN2_063,17,7579419,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser90Ala/c.268T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),2393,96,2559,"0,0375146542",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,61,Tolerated,"25,42","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_069,17,7579419,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser90Ala/c.268T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1152,25,1202,"0,0207986689",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,61,Tolerated,"27,55",14
"low bq, many samples",UPN2_071,17,7579419,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser90Ala/c.268T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),4606,106,4802,"0,0220741358",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,61,Tolerated,"27,18","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_072,17,7579419,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser90Ala/c.268T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),4734,88,4940,"0,0178137652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,61,Tolerated,"27,5","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_073,17,7579419,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser90Ala/c.268T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1303,24,1350,"0,0177777778",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,61,Tolerated,"28,85","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_075,17,7579419,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser90Ala/c.268T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),3493,43,3575,"0,012027972",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,61,Tolerated,"29,03","14,3"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,17,7579419,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser90Ala/c.268T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1712,39,1799,"0,0216787104",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,61,Tolerated,"26,94","14,18"
"low bq, low freq, many artifacts, many samples",UPN2_078,17,7579419,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser90Ala/c.268T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),2487,43,2556,"0,0168231612",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,61,Tolerated,"28,43",14
"low bq, low freq, many artifacts, many samples",UPN2_080,17,7579419,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser90Ala/c.268T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),3209,41,3293,"0,0124506529",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,61,Tolerated,"28,46","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_081,17,7579419,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser90Ala/c.268T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),6698,81,6865,"0,0117989803",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,61,Tolerated,"28,9","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_082,17,7579419,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser90Ala/c.268T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),945,20,988,"0,020242915",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,61,Tolerated,"27,95",14
"low bq, bad alignment, many samples",UPN2_083,17,7579419,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser90Ala/c.268T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1832,64,1928,"0,0331950207",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,61,Tolerated,"26,45","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_084,17,7579419,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser90Ala/c.268T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1757,22,1827,"0,0120415982",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,61,Tolerated,"28,58","14,59"
"low bq, many samples",UPN2_087,17,7579419,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser90Ala/c.268T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),988,23,1040,"0,0221153846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,61,Tolerated,"27,28","14,57"
"low bq, many samples",UPN2_088,17,7579419,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser90Ala/c.268T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),765,22,812,"0,0270935961",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,61,Tolerated,"27,13",14
"low bq, low freq, many artifacts, many samples",UPN2_101,17,7579419,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser90Ala/c.268T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),4613,49,4720,"0,0103813559",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,61,Tolerated,"29,1","14,82"
"low bq, low freq, many artifacts",UPN2_111,17,7579419,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser90Ala/c.268T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),5805,61,5936,"0,0102762803",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,61,Tolerated,"29,34","14,11"
"low freq, many artifacts",UPN2_084,17,7579419,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser90Pro/c.268T>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),1757,24,1827,"0,013136289",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,08",Neutral,266,Tolerated,"28,58","34,25"
"low bq, low freq, many artifacts, many samples",UPN2_001,17,7579419,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser90Thr/c.268T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),3636,39,3701,"0,0105376925",0,0,0,0,1,0,0,0,1,NO,NO,COSM1735384. COSM1735386. COSM1735387. COSM1735385,pancreas,4,NO,NO,NO,NO,NO,NO,"0,49",Neutral,102,Tolerated,"30,28","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_016,17,7579419,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser90Thr/c.268T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),5109,100,5260,"0,0190114068",0,0,0,0,1,0,0,0,1,NO,NO,COSM1735384. COSM1735386. COSM1735387. COSM1735385,pancreas,4,NO,NO,NO,NO,NO,NO,"0,49",Neutral,102,Tolerated,"28,93","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_017,17,7579419,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser90Thr/c.268T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),2591,47,2669,"0,0176095916",0,0,0,0,1,0,0,0,1,NO,NO,COSM1735384. COSM1735386. COSM1735387. COSM1735385,pancreas,4,NO,NO,NO,NO,NO,NO,"0,49",Neutral,102,Tolerated,"28,48","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_018,17,7579419,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser90Thr/c.268T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),5224,94,5369,"0,0175079158",0,0,0,0,1,0,0,0,1,NO,NO,COSM1735384. COSM1735386. COSM1735387. COSM1735385,pancreas,4,NO,NO,NO,NO,NO,NO,"0,49",Neutral,102,Tolerated,"28,82","15,17"
"low bq, low freq, many artifacts, many samples",UPN2_002,17,7579419,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser90Thr/c.268T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),3303,64,3403,"0,0188069351",0,0,0,0,1,0,0,0,1,NO,NO,COSM1735384. COSM1735386. COSM1735387. COSM1735385,pancreas,4,NO,NO,NO,NO,NO,NO,"0,49",Neutral,102,Tolerated,"28,41","14,11"
"low bq, low freq, many artifacts, many samples",UPN2_023,17,7579419,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser90Thr/c.268T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),6889,80,7008,"0,0114155251",0,0,0,0,1,0,0,0,1,NO,NO,COSM1735384. COSM1735386. COSM1735387. COSM1735385,pancreas,4,NO,NO,NO,NO,NO,NO,"0,49",Neutral,102,Tolerated,"30,32","15,29"
"low bq, many samples",UPN2_041,17,7579419,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser90Thr/c.268T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),12516,347,13006,"0,0266799938",0,0,0,0,1,0,0,0,1,NO,NO,COSM1735384. COSM1735386. COSM1735387. COSM1735385,pancreas,4,NO,NO,NO,NO,NO,NO,"0,49",Neutral,102,Tolerated,"28,9","15,56"
"low bq, low freq, many artifacts, many samples",UPN2_042,17,7579419,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser90Thr/c.268T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),12582,162,12841,"0,0126158399",0,0,0,0,1,0,0,0,1,NO,NO,COSM1735384. COSM1735386. COSM1735387. COSM1735385,pancreas,4,NO,NO,NO,NO,NO,NO,"0,49",Neutral,102,Tolerated,"29,97","15,34"
"low bq, low freq, many artifacts, many samples",UPN2_043,17,7579419,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser90Thr/c.268T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),7417,104,7578,"0,0137239377",0,0,0,0,1,0,0,0,1,NO,NO,COSM1735384. COSM1735386. COSM1735387. COSM1735385,pancreas,4,NO,NO,NO,NO,NO,NO,"0,49",Neutral,102,Tolerated,"30,05","15,23"
"low bq, many samples",UPN2_031,17,7579419,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser90Thr/c.268T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),5185,124,5363,"0,0231213873",0,0,0,0,1,0,0,0,1,NO,NO,COSM1735384. COSM1735386. COSM1735387. COSM1735385,pancreas,4,NO,NO,NO,NO,NO,NO,"0,49",Neutral,102,Tolerated,"28,89","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_046,17,7579419,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser90Thr/c.268T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),13643,190,13925,"0,0136445242",0,0,0,0,1,0,0,0,1,NO,NO,COSM1735384. COSM1735386. COSM1735387. COSM1735385,pancreas,4,NO,NO,NO,NO,NO,NO,"0,49",Neutral,102,Tolerated,"30,04","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_033,17,7579419,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser90Thr/c.268T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),5291,119,5466,"0,0217709477",0,0,0,0,1,0,0,0,1,NO,NO,COSM1735384. COSM1735386. COSM1735387. COSM1735385,pancreas,4,NO,NO,NO,NO,NO,NO,"0,49",Neutral,102,Tolerated,"28,98","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_034,17,7579419,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser90Thr/c.268T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),2025,26,2075,"0,0125301205",0,0,0,0,1,0,0,0,1,NO,NO,COSM1735384. COSM1735386. COSM1735387. COSM1735385,pancreas,4,NO,NO,NO,NO,NO,NO,"0,49",Neutral,102,Tolerated,"28,74",14
"low bq, low freq, many artifacts, many samples",UPN2_047,17,7579419,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser90Thr/c.268T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),14121,208,14441,"0,0144034347",0,0,0,0,1,0,0,0,1,NO,NO,COSM1735384. COSM1735386. COSM1735387. COSM1735385,pancreas,4,NO,NO,NO,NO,NO,NO,"0,49",Neutral,102,Tolerated,"29,9","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_048,17,7579419,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser90Thr/c.268T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),13230,195,13504,"0,0144401659",0,0,0,0,1,0,0,0,1,NO,NO,COSM1735384. COSM1735386. COSM1735387. COSM1735385,pancreas,4,NO,NO,NO,NO,NO,NO,"0,49",Neutral,102,Tolerated,"29,97","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_035,17,7579419,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser90Thr/c.268T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),13259,162,13499,"0,012000889",0,0,0,0,1,0,0,0,1,NO,NO,COSM1735384. COSM1735386. COSM1735387. COSM1735385,pancreas,4,NO,NO,NO,NO,NO,NO,"0,49",Neutral,102,Tolerated,"30,39","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_036,17,7579419,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser90Thr/c.268T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),23882,522,24690,"0,0211421628",0,0,0,0,1,0,0,0,1,NO,NO,COSM1735384. COSM1735386. COSM1735387. COSM1735385,pancreas,4,NO,NO,NO,NO,NO,NO,"0,49",Neutral,102,Tolerated,"28,88","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_006,17,7579419,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser90Thr/c.268T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),3724,49,3790,"0,0129287599",0,0,0,0,1,0,0,0,1,NO,NO,COSM1735384. COSM1735386. COSM1735387. COSM1735385,pancreas,4,NO,NO,NO,NO,NO,NO,"0,49",Neutral,102,Tolerated,"29,68","15,16"
"low bq, many samples",UPN2_050,17,7579419,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser90Thr/c.268T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),7830,201,8122,"0,0247475991",0,0,0,0,1,0,0,0,1,NO,NO,COSM1735384. COSM1735386. COSM1735387. COSM1735385,pancreas,4,NO,NO,NO,NO,NO,NO,"0,49",Neutral,102,Tolerated,"28,93","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_052,17,7579419,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser90Thr/c.268T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),6103,93,6224,"0,0149421594",0,0,0,0,1,0,0,0,1,NO,NO,COSM1735384. COSM1735386. COSM1735387. COSM1735385,pancreas,4,NO,NO,NO,NO,NO,NO,"0,49",Neutral,102,Tolerated,"29,88","15,91"
"low bq, many samples",UPN2_053,17,7579419,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser90Thr/c.268T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),11577,288,12014,"0,0239720326",0,0,0,0,1,0,0,0,1,NO,NO,COSM1735384. COSM1735386. COSM1735387. COSM1735385,pancreas,4,NO,NO,NO,NO,NO,NO,"0,49",Neutral,102,Tolerated,"28,86","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_054,17,7579419,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser90Thr/c.268T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),8266,116,8455,"0,0137196925",0,0,0,0,1,0,0,0,1,NO,NO,COSM1735384. COSM1735386. COSM1735387. COSM1735385,pancreas,4,NO,NO,NO,NO,NO,NO,"0,49",Neutral,102,Tolerated,"29,81","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_007,17,7579419,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser90Thr/c.268T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),9413,112,9583,"0,011687363",0,0,0,0,1,0,0,0,1,NO,NO,COSM1735384. COSM1735386. COSM1735387. COSM1735385,pancreas,4,NO,NO,NO,NO,NO,NO,"0,49",Neutral,102,Tolerated,"30,2","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_008,17,7579419,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser90Thr/c.268T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),13428,164,13703,"0,0119681821",0,0,0,0,1,0,0,0,1,NO,NO,COSM1735384. COSM1735386. COSM1735387. COSM1735385,pancreas,4,NO,NO,NO,NO,NO,NO,"0,49",Neutral,102,Tolerated,"29,83","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_009,17,7579419,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser90Thr/c.268T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),10904,111,11084,"0,0100144352",0,0,0,0,1,0,0,0,1,NO,NO,COSM1735384. COSM1735386. COSM1735387. COSM1735385,pancreas,4,NO,NO,NO,NO,NO,NO,"0,49",Neutral,102,Tolerated,"29,96","15,6"
"low bq, low freq, many artifacts, many samples",UPN2_010,17,7579419,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser90Thr/c.268T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),7660,98,7811,"0,0125464089",0,0,0,0,1,0,0,0,1,NO,NO,COSM1735384. COSM1735386. COSM1735387. COSM1735385,pancreas,4,NO,NO,NO,NO,NO,NO,"0,49",Neutral,102,Tolerated,"29,77","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_011,17,7579419,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser90Thr/c.268T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),7241,80,7350,"0,0108843537",0,0,0,0,1,0,0,0,1,NO,NO,COSM1735384. COSM1735386. COSM1735387. COSM1735385,pancreas,4,NO,NO,NO,NO,NO,NO,"0,49",Neutral,102,Tolerated,"30,03",14
"low bq, low freq, many artifacts, many samples",UPN2_055,17,7579419,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser90Thr/c.268T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),12228,181,12484,"0,0144985582",0,0,0,0,1,0,0,0,1,NO,NO,COSM1735384. COSM1735386. COSM1735387. COSM1735385,pancreas,4,NO,NO,NO,NO,NO,NO,"0,49",Neutral,102,Tolerated,"29,9","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_056,17,7579419,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser90Thr/c.268T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),7787,115,7962,"0,0144436071",0,0,0,0,1,0,0,0,1,NO,NO,COSM1735384. COSM1735386. COSM1735387. COSM1735385,pancreas,4,NO,NO,NO,NO,NO,NO,"0,49",Neutral,102,Tolerated,"29,53","14,58"
"low bq, many samples",UPN2_057,17,7579419,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser90Thr/c.268T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),6680,158,6932,"0,0227928448",0,0,0,0,1,0,0,0,1,NO,NO,COSM1735384. COSM1735386. COSM1735387. COSM1735385,pancreas,4,NO,NO,NO,NO,NO,NO,"0,49",Neutral,102,Tolerated,"29,2","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_058,17,7579419,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser90Thr/c.268T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),14034,199,14328,"0,0138888889",0,0,0,0,1,0,0,0,1,NO,NO,COSM1735384. COSM1735386. COSM1735387. COSM1735385,pancreas,4,NO,NO,NO,NO,NO,NO,"0,49",Neutral,102,Tolerated,"30,12","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_012,17,7579419,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser90Thr/c.268T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),4696,58,4793,"0,0121009806",0,0,0,0,1,0,0,0,1,NO,NO,COSM1735384. COSM1735386. COSM1735387. COSM1735385,pancreas,4,NO,NO,NO,NO,NO,NO,"0,49",Neutral,102,Tolerated,"30,1","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_013,17,7579419,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser90Thr/c.268T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),2466,30,2512,"0,0119426752",0,0,0,0,1,0,0,0,1,NO,NO,COSM1735384. COSM1735386. COSM1735387. COSM1735385,pancreas,4,NO,NO,NO,NO,NO,NO,"0,49",Neutral,102,Tolerated,"30,19","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_094,17,7579419,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser90Thr/c.268T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),4322,58,4423,"0,0131132715",0,0,0,0,1,0,0,0,1,NO,NO,COSM1735384. COSM1735386. COSM1735387. COSM1735385,pancreas,4,NO,NO,NO,NO,NO,NO,"0,49",Neutral,102,Tolerated,"29,64","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_100,17,7579419,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser90Thr/c.268T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),5268,66,5380,"0,012267658",0,0,0,0,1,0,0,0,1,NO,NO,COSM1735384. COSM1735386. COSM1735387. COSM1735385,pancreas,4,NO,NO,NO,NO,NO,NO,"0,49",Neutral,102,Tolerated,"29,45","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_107,17,7579419,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser90Thr/c.268T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),6453,74,6607,"0,0112002422",0,0,0,0,1,0,0,0,1,NO,NO,COSM1735384. COSM1735386. COSM1735387. COSM1735385,pancreas,4,NO,NO,NO,NO,NO,NO,"0,49",Neutral,102,Tolerated,"29,39","14,09"
"low bq, low freq, many artifacts",UPN2_110,17,7579419,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser90Thr/c.268T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),5660,64,5787,"0,0110592708",0,0,0,0,1,0,0,0,1,NO,NO,COSM1735384. COSM1735386. COSM1735387. COSM1735385,pancreas,4,NO,NO,NO,NO,NO,NO,"0,49",Neutral,102,Tolerated,"29,15","14,2"
"low bq, low freq, many artifacts, many samples",UPN2_045,17,7579425,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala88Pro/c.262G>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),5875,79,5997,"0,0131732533",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,79",Neutral,264,Tolerated,"27,87","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_049,17,7579425,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala88Pro/c.262G>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),8309,99,8435,"0,0117368109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,79",Neutral,264,Tolerated,"28,03","14,56"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,17,7579425,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala88Pro/c.262G>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),2525,45,2577,"0,0174621653",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,79",Neutral,264,Tolerated,"26,11",14
"low bq, low freq, many artifacts, many samples",UPN2_071,17,7579425,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala88Pro/c.262G>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),4746,63,4821,"0,0130678283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,79",Neutral,264,Tolerated,"27,63","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_075,17,7579425,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala88Pro/c.262G>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),3533,36,3577,"0,0100642997",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,79",Neutral,264,Tolerated,"29,03","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_078,17,7579425,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala88Pro/c.262G>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),2499,29,2558,"0,011336982",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,79",Neutral,264,Tolerated,"28,94",14
"low bq, low freq, many artifacts, many samples",UPN2_083,17,7579425,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala88Pro/c.262G>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),1914,20,1939,"0,0103145952",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,79",Neutral,264,Tolerated,"27,39","15,45"
"low bq, low freq, many artifacts",UPN2_087,17,7579425,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala88Pro/c.262G>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),1025,20,1047,"0,0191021968",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,79",Neutral,264,Tolerated,"27,86",15
"low bq, low freq, many artifacts, many samples",UPN2_045,17,7579449,G,T,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro80Thr/c.238C>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),2914,43,2966,"0,0144976399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,04",Neutral,"0,04",Damaging,"31,08","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_051,17,7579449,G,T,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro80Thr/c.238C>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),5446,59,5517,"0,0106942179",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,04",Neutral,"0,04",Damaging,"32,62","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_045,17,7579452,C,G,missense_variant(MODERATE|MISSENSE|Gct/Cct|p.Ala79Pro/c.235G>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),2910,42,2970,"0,0141414141",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,154,Tolerated,"30,59",14
"low bq, low freq, many artifacts, many samples",UPN2_063,17,7579452,C,G,missense_variant(MODERATE|MISSENSE|Gct/Cct|p.Ala79Pro/c.235G>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),1251,22,1276,"0,0172413793",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,154,Tolerated,"29,39",14
"low bq, low freq, many artifacts, many samples",UPN2_071,17,7579452,C,G,missense_variant(MODERATE|MISSENSE|Gct/Cct|p.Ala79Pro/c.235G>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),2355,31,2391,"0,0129652865",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,154,Tolerated,"31,1",14
"low bq, low freq, many artifacts",UPN2_072,17,7579452,C,G,missense_variant(MODERATE|MISSENSE|Gct/Cct|p.Ala79Pro/c.235G>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),2426,28,2465,"0,0113590264",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,12",Neutral,154,Tolerated,"31,57","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_045,17,7579455,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala78Pro/c.232G>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),2917,35,2975,"0,0117647059",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,23",Neutral,135,Tolerated,"30,43",14
"low bq, low freq, many artifacts, many samples",UPN2_049,17,7579455,C,G,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala78Pro/c.232G>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),4125,46,4206,"0,010936757",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,23",Neutral,135,Tolerated,"30,34",14
"low bq, low freq, many artifacts, many samples",UPN2_044,17,7579460,G,T,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala76Glu/c.227C>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),1015,22,1038,"0,021194605",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,88",Neutral,832,Tolerated,"33,28","20,23"
"low bq, low freq, many artifacts, many samples",UPN2_016,17,7579469,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val73Glu/c.218T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),2605,27,2641,"0,0102234002",0,0,0,0,1,0,0,0,1,NO,NO,COSM44556,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"0,16",Neutral,319,Tolerated,"32,74","17,74"
"low bq, low freq, many artifacts, many samples",UPN2_018,17,7579469,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val73Glu/c.218T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),2645,43,2700,"0,0159259259",0,0,0,0,1,0,0,0,1,NO,NO,COSM44556,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"0,16",Neutral,319,Tolerated,"33,08","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_022,17,7579469,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val73Glu/c.218T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),3614,40,3668,"0,0109051254",0,0,0,0,1,0,0,0,1,NO,NO,COSM44556,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"0,16",Neutral,319,Tolerated,"33,98","18,1"
"low bq, low freq, many artifacts, many samples",UPN2_023,17,7579469,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val73Glu/c.218T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),3449,38,3498,"0,0108633505",0,0,0,0,1,0,0,0,1,NO,NO,COSM44556,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"0,16",Neutral,319,Tolerated,"33,98","17,55"
"low bq, low freq, many artifacts, many samples",UPN2_041,17,7579469,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val73Glu/c.218T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),6342,107,6496,"0,0164716749",0,0,0,0,1,0,0,0,1,NO,NO,COSM44556,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"0,16",Neutral,319,Tolerated,"32,43","17,48"
"low bq, low freq, many artifacts, many samples",UPN2_042,17,7579469,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val73Glu/c.218T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),6295,84,6406,"0,0131127068",0,0,0,0,1,0,0,0,1,NO,NO,COSM44556,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"0,16",Neutral,319,Tolerated,"33,27","16,43"
"low bq, low freq, many artifacts, many samples",UPN2_028,17,7579469,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val73Glu/c.218T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),3688,38,3736,"0,0101713062",0,0,0,0,1,0,0,0,1,NO,NO,COSM44556,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"0,16",Neutral,319,Tolerated,"34,02","18,53"
"low bq, many samples",UPN2_044,17,7579469,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val73Glu/c.218T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),1007,29,1040,"0,0278846154",0,0,0,0,1,0,0,0,1,NO,NO,COSM44556,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"0,16",Neutral,319,Tolerated,"31,35","15,45"
"low bq, low freq, many artifacts, many samples",UPN2_030,17,7579469,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val73Glu/c.218T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),3764,49,3834,"0,012780386",0,0,0,0,1,0,0,0,1,NO,NO,COSM44556,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"0,16",Neutral,319,Tolerated,"33,04","17,24"
"low bq, low freq, many artifacts, many samples",UPN2_045,17,7579469,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val73Glu/c.218T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),2921,51,3002,"0,0169886742",0,0,0,0,1,0,0,0,1,NO,NO,COSM44556,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"0,16",Neutral,319,Tolerated,"31,44","15,53"
"low bq, low freq, many artifacts, many samples",UPN2_033,17,7579469,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val73Glu/c.218T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),2673,46,2739,"0,0167944505",0,0,0,0,1,0,0,0,1,NO,NO,COSM44556,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"0,16",Neutral,319,Tolerated,"33,05","14,15"
"low bq, low freq, many artifacts, many samples",UPN2_035,17,7579469,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val73Glu/c.218T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),6647,75,6740,"0,0111275964",0,0,0,0,1,0,0,0,1,NO,NO,COSM44556,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"0,16",Neutral,319,Tolerated,"33,97","16,71"
"low bq, low freq, many artifacts, many samples",UPN2_036,17,7579469,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val73Glu/c.218T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),12141,157,12388,"0,0126735551",0,0,0,0,1,0,0,0,1,NO,NO,COSM44556,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"0,16",Neutral,319,Tolerated,"32,91","16,48"
"low bq, low freq, many artifacts, many samples",UPN2_049,17,7579469,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val73Glu/c.218T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),4132,79,4243,"0,0186189017",0,0,0,0,1,0,0,0,1,NO,NO,COSM44556,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"0,16",Neutral,319,Tolerated,"31,31","16,05"
"low bq, low freq, many artifacts, many samples",UPN2_050,17,7579469,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val73Glu/c.218T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),3976,79,4084,"0,0193437806",0,0,0,0,1,0,0,0,1,NO,NO,COSM44556,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"0,16",Neutral,319,Tolerated,"32,55","17,63"
"low bq, low freq, many artifacts, many samples",UPN2_051,17,7579469,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val73Glu/c.218T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),5431,89,5546,"0,0160476019",0,0,0,0,1,0,0,0,1,NO,NO,COSM44556,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"0,16",Neutral,319,Tolerated,"32,43","16,4"
"low bq, low freq, many artifacts, many samples",UPN2_052,17,7579469,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val73Glu/c.218T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),3063,39,3112,"0,0125321337",0,0,0,0,1,0,0,0,1,NO,NO,COSM44556,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"0,16",Neutral,319,Tolerated,"33,27","17,72"
"low bq, low freq, many artifacts, many samples",UPN2_039,17,7579469,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val73Glu/c.218T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),12341,161,12590,"0,0127879269",0,0,0,0,1,0,0,0,1,NO,NO,COSM44556,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"0,16",Neutral,319,Tolerated,"32,64","16,86"
"low bq, low freq, many artifacts, many samples",UPN2_053,17,7579469,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val73Glu/c.218T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),5920,97,6051,"0,0160304082",0,0,0,0,1,0,0,0,1,NO,NO,COSM44556,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"0,16",Neutral,319,Tolerated,"32,33","15,73"
"low bq, low freq, many artifacts, many samples",UPN2_009,17,7579469,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val73Glu/c.218T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),5479,57,5549,"0,0102721211",0,0,0,0,1,0,0,0,1,NO,NO,COSM44556,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"0,16",Neutral,319,Tolerated,"33,91","16,11"
"low bq, low freq, many artifacts, many samples",UPN2_011,17,7579469,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val73Glu/c.218T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),3612,43,3667,"0,0117262067",0,0,0,0,1,0,0,0,1,NO,NO,COSM44556,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"0,16",Neutral,319,Tolerated,"33,84","16,63"
"low bq, low freq, many artifacts, many samples",UPN2_055,17,7579469,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val73Glu/c.218T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),6142,83,6252,"0,0132757518",0,0,0,0,1,0,0,0,1,NO,NO,COSM44556,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"0,16",Neutral,319,Tolerated,"33,22","18,41"
"low bq, low freq, many artifacts, many samples",UPN2_056,17,7579469,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val73Glu/c.218T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),3892,61,3968,"0,0153729839",0,0,0,0,1,0,0,0,1,NO,NO,COSM44556,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"0,16",Neutral,319,Tolerated,"33,21",17
"low bq, low freq, many artifacts, many samples",UPN2_057,17,7579469,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val73Glu/c.218T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),3401,49,3468,"0,0141291811",0,0,0,0,1,0,0,0,1,NO,NO,COSM44556,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"0,16",Neutral,319,Tolerated,"32,83","16,14"
"low bq, low freq, many artifacts, many samples",UPN2_040,17,7579469,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val73Glu/c.218T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),5521,72,5627,"0,0127954505",0,0,0,0,1,0,0,0,1,NO,NO,COSM44556,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"0,16",Neutral,319,Tolerated,"32,84","17,07"
"low bq, low freq, many artifacts, many samples",UPN2_071,17,7579469,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val73Glu/c.218T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),2367,29,2409,"0,0120381901",0,0,0,0,1,0,0,0,1,NO,NO,COSM44556,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"0,16",Neutral,319,Tolerated,"32,34","17,48"
"low bq, low freq, many artifacts, many samples",UPN2_072,17,7579469,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val73Glu/c.218T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),2429,36,2475,"0,0145454545",0,0,0,0,1,0,0,0,1,NO,NO,COSM44556,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"0,16",Neutral,319,Tolerated,"32,58","17,36"
"low bq, low freq, many artifacts",UPN2_081,17,7579469,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val73Glu/c.218T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),3377,36,3423,"0,0105170903",0,0,0,0,1,0,0,0,1,NO,NO,COSM44556,central_nervous_system,1,NO,NO,NO,NO,NO,NO,"0,16",Neutral,319,Tolerated,"33,68","15,17"
"low freq, many artifacts",UPN2_036,17,7579470,C,CG,frameshift_variant(HIGH||ccc/cccC|p.Val73fs/c.216dupC|393|TP53|protein_coding|CODING|ENST00000269305|4|CG),12254,145,12393,"0,0117001533",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,34",NA
"low freq, many artifacts",UPN2_039,17,7579470,C,CG,frameshift_variant(HIGH||ccc/cccC|p.Val73fs/c.216dupC|393|TP53|protein_coding|CODING|ENST00000269305|4|CG),12414,162,12594,"0,0128632682",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,19",NA
"low bq, many samples",UPN2_063,17,7579470,C,G,missense_variant(MODERATE|MISSENSE|Gtg/Ctg|p.Val73Leu/c.217G>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),1263,36,1301,"0,0276710223",0,0,0,0,1,0,0,0,1,NO,NO,COSM45288,urinary_tract,2,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,686,Tolerated,"29,34","15,5"
"low bq, low freq, many artifacts, many samples",UPN2_094,17,7579470,C,G,missense_variant(MODERATE|MISSENSE|Gtg/Ctg|p.Val73Leu/c.217G>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),2192,23,2220,"0,0103603604",0,0,0,0,1,0,0,0,1,NO,NO,COSM45288,urinary_tract,2,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,686,Tolerated,"32,52","16,3"
"low bq, low freq, many artifacts, many samples",UPN2_100,17,7579470,C,G,missense_variant(MODERATE|MISSENSE|Gtg/Ctg|p.Val73Leu/c.217G>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),2665,34,2705,"0,0125693161",0,0,0,0,1,0,0,0,1,NO,NO,COSM45288,urinary_tract,2,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,686,Tolerated,"32,16","16,74"
"low bq, low freq, many artifacts, many samples",UPN2_101,17,7579470,C,G,missense_variant(MODERATE|MISSENSE|Gtg/Ctg|p.Val73Leu/c.217G>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),2335,27,2366,"0,0114116653",0,0,0,0,1,0,0,0,1,NO,NO,COSM45288,urinary_tract,2,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,686,Tolerated,"32,24",14
"low bq, low freq, many artifacts, many samples",UPN2_107,17,7579470,C,G,missense_variant(MODERATE|MISSENSE|Gtg/Ctg|p.Val73Leu/c.217G>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),3273,34,3312,"0,0102657005",0,0,0,0,1,0,0,0,1,NO,NO,COSM45288,urinary_tract,2,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,686,Tolerated,"32,29","15,03"
"low bq, low freq, many artifacts",UPN2_110,17,7579470,C,G,missense_variant(MODERATE|MISSENSE|Gtg/Ctg|p.Val73Leu/c.217G>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),2869,39,2912,"0,0133928571",0,0,0,0,1,0,0,0,1,NO,NO,COSM45288,urinary_tract,2,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,686,Tolerated,"32,14","14,36"
"low freq, many artifacts, many samples",UPN2_045,17,7579470,CG,C,frameshift_variant(HIGH||ccc/|p.Val73fs/c.216delC|393|TP53|protein_coding|CODING|ENST00000269305|4|C),2969,39,3021,"0,0129096326",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,42",NA
"low freq, many artifacts, many samples",UPN2_049,17,7579470,CG,C,frameshift_variant(HIGH||ccc/|p.Val73fs/c.216delC|393|TP53|protein_coding|CODING|ENST00000269305|4|C),4197,44,4263,"0,0103213699",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,45",NA
"low bq, low freq, many artifacts",UPN2_090,17,7579482,C,T,missense_variant(MODERATE|MISSENSE|Gct/Act|p.Ala69Thr/c.205G>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),1627,21,1651,"0,0127195639",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,13",Neutral,"0,154",Tolerated,"34,25","27,67"
"low bq, low freq, many artifacts, many samples",UPN2_062,17,7579484,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu68Ala/c.203A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),2074,24,2100,"0,0114285714",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,2",Neutral,"0,8",Tolerated,"28,12","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_041,17,7579490,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met66Lys/c.197T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),6419,83,6526,"0,0127183573",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,228,Tolerated,"34,03","18,22"
"low bq, low freq, many artifacts, many samples",UPN2_042,17,7579490,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met66Lys/c.197T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),6313,69,6411,"0,0107627515",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,228,Tolerated,"34,02","16,2"
"low bq, low freq, many artifacts, many samples",UPN2_043,17,7579490,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met66Lys/c.197T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),3721,43,3779,"0,0113786716",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,228,Tolerated,"33,95","17,3"
"low bq, low freq, many artifacts, many samples",UPN2_045,17,7579490,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met66Lys/c.197T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),2968,45,3031,"0,0148465853",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,228,Tolerated,"33,83","16,73"
"low bq, low freq, many artifacts, many samples",UPN2_046,17,7579490,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met66Lys/c.197T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),6883,73,6977,"0,0104629497",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,228,Tolerated,"34,11","17,25"
"low bq, low freq, many artifacts, many samples",UPN2_033,17,7579490,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met66Lys/c.197T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),2712,29,2749,"0,0105492907",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,228,Tolerated,"34,59","18,66"
"low bq, low freq, many artifacts, many samples",UPN2_047,17,7579490,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met66Lys/c.197T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),7117,78,7217,"0,0108078149",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,228,Tolerated,"33,89","17,58"
"low bq, low freq, many artifacts, many samples",UPN2_048,17,7579490,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met66Lys/c.197T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),6653,69,6733,"0,0102480321",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,228,Tolerated,"33,96","18,58"
"low bq, low freq, many artifacts, many samples",UPN2_051,17,7579490,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met66Lys/c.197T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),5477,69,5566,"0,0123966942",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,228,Tolerated,"34,08","15,97"
"low bq, low freq, many artifacts, many samples",UPN2_052,17,7579490,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met66Lys/c.197T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),3072,38,3121,"0,0121755847",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,228,Tolerated,"34,02","18,18"
"low bq, low freq, many artifacts, many samples",UPN2_053,17,7579490,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met66Lys/c.197T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),5985,67,6071,"0,0110360731",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,228,Tolerated,34,"18,09"
"low bq, low freq, many artifacts, many samples",UPN2_054,17,7579490,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met66Lys/c.197T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),4167,47,4234,"0,0111006141",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,228,Tolerated,"34,1","17,34"
"low bq, low freq, many artifacts, many samples",UPN2_007,17,7579490,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met66Lys/c.197T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),4748,49,4810,"0,0101871102",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,228,Tolerated,"34,5","19,12"
"low bq, low freq, many artifacts, many samples",UPN2_056,17,7579490,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met66Lys/c.197T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),3922,42,3974,"0,0105686965",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,228,Tolerated,"33,96","19,24"
"low bq, low freq, many artifacts",UPN2_058,17,7579490,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met66Lys/c.197T>A|393|TP53|protein_coding|CODING|ENST00000269305|4|T),7032,98,7160,"0,0136871508",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,75",Neutral,228,Tolerated,"34,01","16,56"
"low bq, low freq, many artifacts, many samples",UPN2_014,17,7579494,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg65*/c.193A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),10271,110,10600,"0,0103773585",0,0,0,0,1,0,0,0,1,NO,NO,COSM707854. COSM707853. COSM10885. COSM1646878. COSM3958857,lung. ovary. urinary_tract,16. 1. 5,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,73","25,74"
"low bq, low freq, many artifacts, many samples",UPN2_017,17,7579494,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg65*/c.193A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),4092,48,4247,"0,0113020956",0,0,0,0,1,0,0,0,1,NO,NO,COSM707854. COSM707853. COSM10885. COSM1646878. COSM3958857,lung. ovary. urinary_tract,16. 1. 5,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,71","24,88"
"low bq, low freq, many artifacts, many samples",UPN2_004,17,7579494,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg65*/c.193A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),1910,27,2002,"0,0134865135",0,0,0,0,1,0,0,0,1,NO,NO,COSM707854. COSM707853. COSM10885. COSM1646878. COSM3958857,lung. ovary. urinary_tract,16. 1. 5,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,94",24
"low bq, low freq, many artifacts, many samples",UPN2_028,17,7579494,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg65*/c.193A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),11447,135,11769,"0,0114708132",0,0,0,0,1,0,0,0,1,NO,NO,COSM707854. COSM707853. COSM10885. COSM1646878. COSM3958857,lung. ovary. urinary_tract,16. 1. 5,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,66","26,5"
"low bq, low freq, many artifacts, many samples",UPN2_043,17,7579494,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg65*/c.193A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),13827,149,14187,"0,0105025728",0,0,0,0,1,0,0,0,1,NO,NO,COSM707854. COSM707853. COSM10885. COSM1646878. COSM3958857,lung. ovary. urinary_tract,16. 1. 5,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,32","23,98"
"low freq, many artifacts, many samples",UPN2_044,17,7579494,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg65*/c.193A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),4543,58,4719,"0,0122907396",0,0,0,0,1,0,0,0,1,NO,NO,COSM707854. COSM707853. COSM10885. COSM1646878. COSM3958857,lung. ovary. urinary_tract,16. 1. 5,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,09","27,71"
"low bq, low freq, many artifacts, many samples",UPN2_045,17,7579494,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg65*/c.193A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),16742,194,17077,"0,0113603092",0,0,0,0,1,0,0,0,1,NO,NO,COSM707854. COSM707853. COSM10885. COSM1646878. COSM3958857,lung. ovary. urinary_tract,16. 1. 5,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,99","25,15"
"low bq, low freq, many artifacts, many samples",UPN2_047,17,7579494,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg65*/c.193A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),29365,315,30040,"0,0104860186",0,0,0,0,1,0,0,0,1,NO,NO,COSM707854. COSM707853. COSM10885. COSM1646878. COSM3958857,lung. ovary. urinary_tract,16. 1. 5,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,2","24,59"
"low bq, low freq, many artifacts, many samples",UPN2_036,17,7579494,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg65*/c.193A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),41503,448,42878,"0,0104482485",0,0,0,0,1,0,0,0,1,NO,NO,COSM707854. COSM707853. COSM10885. COSM1646878. COSM3958857,lung. ovary. urinary_tract,16. 1. 5,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,6","25,58"
"low bq, low freq, many artifacts, many samples",UPN2_006,17,7579494,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg65*/c.193A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),6198,92,6503,"0,0141473166",0,0,0,0,1,0,0,0,1,NO,NO,COSM707854. COSM707853. COSM10885. COSM1646878. COSM3958857,lung. ovary. urinary_tract,16. 1. 5,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,49","26,79"
"low bq, low freq, many artifacts, many samples",UPN2_050,17,7579494,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg65*/c.193A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),18732,207,19113,"0,0108303249",0,0,0,0,1,0,0,0,1,NO,NO,COSM707854. COSM707853. COSM10885. COSM1646878. COSM3958857,lung. ovary. urinary_tract,16. 1. 5,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,09","24,43"
"low bq, low freq, many artifacts, many samples",UPN2_051,17,7579494,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg65*/c.193A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),16360,176,16688,"0,0105465005",0,0,0,0,1,0,0,0,1,NO,NO,COSM707854. COSM707853. COSM10885. COSM1646878. COSM3958857,lung. ovary. urinary_tract,16. 1. 5,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,62","24,64"
"low bq, low freq, many artifacts, many samples",UPN2_007,17,7579494,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg65*/c.193A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),16404,185,16947,"0,0109163864",0,0,0,0,1,0,0,0,1,NO,NO,COSM707854. COSM707853. COSM10885. COSM1646878. COSM3958857,lung. ovary. urinary_tract,16. 1. 5,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,46","23,95"
"low freq, many artifacts",UPN2_069,17,7579494,T,A,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg65*/c.193A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),3063,38,3176,"0,0119647355",0,0,0,0,1,0,0,0,1,NO,NO,COSM707854. COSM707853. COSM10885. COSM1646878. COSM3958857,lung. ovary. urinary_tract,16. 1. 5,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,02","29,26"
"low freq, many artifacts",UPN2_085,17,7579502,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu62Ala/c.185A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),1341,24,1372,"0,0174927114",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,93",Neutral,48,Damaging,"34,4","33,38"
"low freq, many artifacts, many samples",UPN2_047,17,7579505,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp61Ala/c.182A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),29722,355,30309,"0,0117126926",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,272,Tolerated,"34,9","34,79"
"low freq, many artifacts, many samples",UPN2_090,17,7579505,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp61Ala/c.182A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),7750,121,7909,"0,0152990264",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,272,Tolerated,"35,34","35,29"
"low freq, many artifacts, many samples",UPN2_072,17,7579505,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp61Ala/c.182A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),6884,73,6995,"0,0104360257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,272,Tolerated,"34,71","34,23"
"low freq, many artifacts, many samples",UPN2_079,17,7579505,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp61Ala/c.182A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),2758,29,2800,"0,0103571429",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,272,Tolerated,"34,86","35,1"
"low freq, many artifacts, many samples",UPN2_082,17,7579505,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp61Ala/c.182A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),1924,30,1968,"0,0152439024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,272,Tolerated,"34,96","33,53"
"low freq, many artifacts",UPN2_084,17,7579505,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp61Ala/c.182A>C|393|TP53|protein_coding|CODING|ENST00000269305|4|G),3655,40,3710,"0,0107816712",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,272,Tolerated,"34,69","33,4"
"low freq, many artifacts",UPN2_077,17,7579510,AC,A,frameshift_variant(HIGH||ggt/|p.Gly59fs/c.176delG|393|TP53|protein_coding|CODING|ENST00000269305|4|A),2065,22,2095,"0,0105011933",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,58",NA
"low bq, low freq, many artifacts, many samples",UPN2_043,17,7579532,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln52Leu/c.155A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),14057,152,14266,"0,0106547035",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,239,Tolerated,"34,58","22,31"
"low bq, low freq, many artifacts, many samples",UPN2_050,17,7579532,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln52Leu/c.155A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),19027,194,19293,"0,0100554605",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,239,Tolerated,"34,62","19,93"
"low bq, low freq, many artifacts, many samples",UPN2_054,17,7579532,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln52Leu/c.155A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),14173,147,14384,"0,0102196885",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,239,Tolerated,"34,72","22,24"
"low bq, low freq, many artifacts, many samples",UPN2_042,17,7579539,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile50Phe/c.148A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),21595,233,21889,"0,010644616",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,101,Tolerated,"34,01","16,88"
"low bq, low freq, many artifacts, many samples",UPN2_043,17,7579539,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile50Phe/c.148A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),14081,149,14269,"0,0104422174",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,101,Tolerated,"33,93","16,46"
"low bq, low freq, many artifacts, many samples",UPN2_044,17,7579539,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile50Phe/c.148A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),4667,64,4743,"0,0134935695",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,101,Tolerated,"33,84","20,95"
"low bq, low freq, many artifacts, many samples",UPN2_045,17,7579539,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile50Phe/c.148A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),16945,222,17221,"0,0128912374",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,101,Tolerated,"33,97","16,18"
"low bq, low freq, many artifacts, many samples",UPN2_048,17,7579539,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile50Phe/c.148A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),27367,295,27724,"0,0106406002",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,101,Tolerated,"33,94","16,82"
"low bq, low freq, many artifacts, many samples",UPN2_049,17,7579539,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile50Phe/c.148A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),15066,189,15290,"0,0123610203",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,101,Tolerated,"33,83","16,21"
"low bq, low freq, many artifacts, many samples",UPN2_050,17,7579539,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile50Phe/c.148A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),19002,227,19294,"0,0117653156",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,101,Tolerated,"33,88","16,5"
"low bq, low freq, many artifacts, many samples",UPN2_056,17,7579539,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile50Phe/c.148A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),13982,152,14171,"0,0107261308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,101,Tolerated,"34,06","15,91"
"low bq, low freq, many artifacts",UPN2_057,17,7579539,T,A,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile50Phe/c.148A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),15057,169,15269,"0,0110681774",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,101,Tolerated,"33,94","17,49"
many samples,UPN2_001,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),6025,152,6200,"0,024516129",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,93,Tolerated,"33,3","30,43"
"low freq, many artifacts, many samples",UPN2_014,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),10343,221,10600,"0,0208490566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,93,Tolerated,"33,48","30,3"
"low freq, many artifacts, many samples",UPN2_015,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),16016,252,16320,"0,0154411765",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,93,Tolerated,"33,46","30,37"
"low freq, many artifacts, many samples",UPN2_016,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),6737,130,6888,"0,018873403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,93,Tolerated,"33,14","30,64"
many samples,UPN2_017,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),4122,99,4237,"0,0233655889",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,93,Tolerated,"33,42","31,16"
"low freq, many artifacts, many samples",UPN2_018,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),7038,150,7213,"0,0207957854",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,93,Tolerated,"33,23","30,37"
"low freq, many artifacts, many samples",UPN2_019,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),8804,197,9035,"0,0218040952",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,93,Tolerated,"33,39","29,96"
"low freq, many artifacts, many samples",UPN2_020,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),7013,131,7166,"0,0182807703",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,93,Tolerated,"33,54","30,69"
"low freq, many artifacts, many samples",UPN2_021,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),9070,191,9293,"0,0205531045",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,93,Tolerated,"33,43","30,53"
"low freq, many artifacts, many samples",UPN2_002,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),6126,132,6273,"0,0210425634",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,93,Tolerated,"33,32","31,32"
"low freq, many artifacts, many samples",UPN2_003,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1496,28,1534,"0,0182529335",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,93,Tolerated,"33,68","29,43"
"many samples, low freq, no database",UPN2_022,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),11635,184,11844,"0,0155352921",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,"0,093",Tolerated,"33,42","30,72"
"low freq, many artifacts, many samples",UPN2_023,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),11813,222,12075,"0,0183850932",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,93,Tolerated,"33,49","30,02"
"many samples, low freq, no database",UPN2_024,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),5586,71,5673,"0,0125154239",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,"0,093",Tolerated,"33,61","31,68"
"low freq, many artifacts, many samples",UPN2_025,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),15268,259,15572,"0,0166324172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,93,Tolerated,"33,34","30,48"
"many samples, low freq, no database",UPN2_026,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),13043,270,13352,"0,0202216896",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,"0,093",Tolerated,"33,51","30,67"
many samples,UPN2_027,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),13981,323,14342,"0,0225212662",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,93,Tolerated,"33,52","30,41"
"low freq, many artifacts, many samples",UPN2_028,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),11493,253,11780,"0,0214770798",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,93,Tolerated,"33,48","31,1"
"low freq, many artifacts, many samples",UPN2_029,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),12973,256,13283,"0,0192727546",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,93,Tolerated,"33,58","30,64"
"low freq, many artifacts, many samples",UPN2_030,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),11259,227,11513,"0,0197168418",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,93,Tolerated,"33,42","30,71"
"many samples, low freq, no database",UPN2_031,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),7659,137,7817,"0,0175259051",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,"0,093",Tolerated,"33,29","30,04"
many samples,UPN2_005,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),2185,59,2251,"0,0262105731",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,93,Tolerated,"33,43","30,41"
"low freq, many artifacts, many samples",UPN2_032,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),4683,67,4762,"0,0140697186",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,93,Tolerated,"33,56","28,88"
"many samples, low freq, no database",UPN2_046,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),22390,307,22799,"0,0134655029",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,"0,093",Tolerated,"32,84","29,38"
"many samples, low freq, no database",UPN2_033,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),8911,157,9094,"0,0172641302",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,"0,093",Tolerated,"33,44","29,45"
"low freq, many artifacts, many samples",UPN2_034,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),3580,43,3640,"0,0118131868",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,93,Tolerated,"33,65","29,91"
"many samples, low freq, no database",UPN2_048,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),27206,306,27640,"0,0110709117",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,"0,093",Tolerated,"32,87","28,2"
"many samples, low freq, no database",UPN2_035,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),21310,441,21812,"0,0202182285",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,"0,093",Tolerated,"33,46","30,58"
"low freq, many artifacts, many samples",UPN2_036,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),42067,898,43093,"0,0208386513",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,93,Tolerated,"33,48","30,4"
"many samples, low freq, no database",UPN2_006,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),6287,160,6462,"0,0247601362",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,"0,093",Tolerated,"33,41","30,39"
"many samples, low freq, no database",UPN2_037,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),18903,373,19318,"0,019308417",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,"0,093",Tolerated,"33,49","30,36"
many samples,UPN2_038,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),19174,437,19670,"0,0222165735",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,93,Tolerated,"33,38","30,48"
"many samples, low freq, no database",UPN2_039,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),33158,846,34085,"0,0248203022",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,"0,093",Tolerated,"33,29","30,77"
"low freq, many artifacts, many samples",UPN2_053,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),18542,204,18833,"0,0108320501",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,93,Tolerated,"32,69","27,65"
"low freq, many artifacts, many samples",UPN2_007,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),16557,353,16974,"0,0207965123",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,93,Tolerated,"33,32","30,7"
"many samples, low freq, no database",UPN2_008,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),22774,468,23334,"0,0200565698",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,"0,093",Tolerated,"33,3","30,32"
"low freq, many artifacts, many samples",UPN2_009,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),18991,356,19406,"0,0183448418",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,93,Tolerated,"33,31","30,18"
"low freq, many artifacts, many samples",UPN2_010,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),13226,268,13528,"0,0198107629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,93,Tolerated,"33,27","30,61"
"low freq, many artifacts, many samples",UPN2_011,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),14638,309,14987,"0,0206178688",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,93,Tolerated,"33,39","30,17"
"many samples, low freq, no database",UPN2_058,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),20588,331,20999,"0,0157626554",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,"0,093",Tolerated,"32,73","29,38"
"many samples, low freq, no database",UPN2_059,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1745,41,1795,"0,0228412256",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,"0,093",Tolerated,"33,08","29,71"
many samples,UPN2_012,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),8340,193,8563,"0,0225388298",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,93,Tolerated,"33,28","30,32"
"many samples, low freq, no database",UPN2_060,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),3794,73,3882,"0,0188047398",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,"0,093",Tolerated,"32,69","30,21"
"low freq, many artifacts, many samples",UPN2_040,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),20585,350,20979,"0,01668335",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,93,Tolerated,"33,57","30,44"
"many samples, low freq, no database",UPN2_013,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),4263,88,4371,"0,0201326927",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,"0,093",Tolerated,"33,3","30,73"
"many samples, low freq, no database",UPN2_061,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),4442,94,4546,"0,0206775187",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,"0,093",Tolerated,"32,78","28,72"
many samples,UPN2_062,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),7739,192,7969,"0,0240933618",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,93,Tolerated,"32,73","29,61"
many samples,UPN2_063,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),2661,117,2785,"0,042010772",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,93,Tolerated,"32,42","30,27"
"many samples, low freq, no database",UPN2_064,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),2405,85,2496,"0,0340544872",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,"0,093",Tolerated,"32,66","29,28"
"many samples, low freq, no database",UPN2_068,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1755,32,1793,"0,0178471835",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,"0,093",Tolerated,"32,84","27,16"
"many samples, low freq, no database",UPN2_069,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),3117,48,3176,"0,0151133501",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,"0,093",Tolerated,"33,14","27,27"
"many samples, low freq, no database",UPN2_070,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),2211,52,2268,"0,0229276896",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,"0,093",Tolerated,"32,92","29,75"
many samples,UPN2_071,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),6075,213,6310,"0,0337559429",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,93,Tolerated,"32,49","29,79"
"many samples, low freq, no database",UPN2_072,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),6703,204,6929,"0,0294414778",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,"0,093",Tolerated,"32,54","30,31"
"low freq, many artifacts, many samples",UPN2_073,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),2840,43,2890,"0,0148788927",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,93,Tolerated,"32,62","28,56"
many samples,UPN2_075,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),6815,171,7015,"0,0243763364",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,93,Tolerated,"32,86","29,31"
many samples,UPN2_076,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),2976,86,3078,"0,0279402209",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,93,Tolerated,"32,65","30,01"
"many samples, low freq, no database",UPN2_077,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),2039,40,2088,"0,0191570881",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,"0,093",Tolerated,"32,83","27,85"
"low freq, many artifacts, many samples",UPN2_078,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),4899,104,5024,"0,0207006369",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,93,Tolerated,"32,96","28,67"
"low freq, many artifacts, many samples",UPN2_079,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),2724,59,2791,"0,0211393766",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,93,Tolerated,"32,8","29,25"
"many samples, low freq, no database",UPN2_080,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),5639,142,5803,"0,0244701017",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,"0,093",Tolerated,"32,67","29,07"
"many samples, low freq, no database",UPN2_081,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),9456,236,9733,"0,0242474057",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,"0,093",Tolerated,"32,54","29,81"
"many samples, low freq, no database",UPN2_082,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1909,35,1955,"0,0179028133",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,"0,093",Tolerated,"32,66","28,77"
many samples,UPN2_083,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),2921,94,3028,"0,0310435931",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,93,Tolerated,"32,64","29,85"
"low freq, many artifacts, many samples",UPN2_084,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),3616,66,3694,"0,017866811",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,93,Tolerated,"32,6","30,2"
"many samples, low freq, no database",UPN2_085,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1335,26,1363,"0,0190755686",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,"0,093",Tolerated,"32,7","29,92"
"low freq, many artifacts, many samples",UPN2_087,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1778,38,1818,"0,0209020902",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,93,Tolerated,"32,64","28,87"
"inspected, low freq, neutral effect",UPN2_088,17,7579548,G,C,missense_variant(MODERATE|MISSENSE|Ccg/Gcg|p.Pro47Ala/c.139C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1378,38,1423,"0,0267041462",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,93,Tolerated,"32,59","29,97"
"low bq, low freq, many artifacts",UPN2_064,17,7579551,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser46Ala/c.136T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),1591,24,1621,"0,0148056755",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,11",Neutral,214,Tolerated,"31,41","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_041,17,7579562,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp42Val/c.125A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),16054,168,16316,"0,0102966413",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,49",Neutral,98,Tolerated,"33,79","17,23"
"low bq, low freq, many artifacts, many samples",UPN2_042,17,7579562,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp42Val/c.125A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),15237,171,15460,"0,0110608021",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,49",Neutral,98,Tolerated,"33,81","18,08"
"low bq, low freq, many artifacts, many samples",UPN2_043,17,7579562,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp42Val/c.125A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),10341,115,10484,"0,0109690958",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,49",Neutral,98,Tolerated,"33,84","16,8"
"low bq, low freq, many artifacts, many samples",UPN2_045,17,7579562,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp42Val/c.125A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),13970,159,14180,"0,011212976",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,49",Neutral,98,Tolerated,"33,82","18,32"
"low bq, low freq, many artifacts, many samples",UPN2_047,17,7579562,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp42Val/c.125A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),22770,241,23088,"0,0104383229",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,49",Neutral,98,Tolerated,"33,85","18,12"
"low bq, low freq, many artifacts, many samples",UPN2_048,17,7579562,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp42Val/c.125A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),20658,232,20974,"0,011061314",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,49",Neutral,98,Tolerated,"33,78","19,47"
"low bq, low freq, many artifacts, many samples",UPN2_049,17,7579562,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp42Val/c.125A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),10848,133,11003,"0,0120876125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,49",Neutral,98,Tolerated,"33,48","16,25"
"low bq, low freq, many artifacts, many samples",UPN2_050,17,7579562,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp42Val/c.125A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),14965,157,15191,"0,0103350668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,49",Neutral,98,Tolerated,"33,77","16,24"
"low bq, low freq, many artifacts, many samples",UPN2_053,17,7579562,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp42Val/c.125A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),12633,138,12818,"0,0107661102",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,49",Neutral,98,Tolerated,"33,64","17,39"
"low bq, low freq, many artifacts, many samples",UPN2_054,17,7579562,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp42Val/c.125A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),9965,127,10141,"0,0125234198",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,49",Neutral,98,Tolerated,"33,72","17,15"
"low bq, low freq, many artifacts, many samples",UPN2_011,17,7579562,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp42Val/c.125A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),11215,116,11353,"0,0102175636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,49",Neutral,98,Tolerated,"34,19","18,28"
"low bq, low freq, many artifacts, many samples",UPN2_055,17,7579562,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp42Val/c.125A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),16323,192,16577,"0,0115823128",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,49",Neutral,98,Tolerated,"33,66","17,63"
"low bq, low freq, many artifacts, many samples",UPN2_056,17,7579562,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp42Val/c.125A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),10016,117,10187,"0,0114852263",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,49",Neutral,98,Tolerated,"33,74","16,18"
"low bq, low freq, many artifacts, many samples",UPN2_057,17,7579562,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp42Val/c.125A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),11595,131,11775,"0,0111252654",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,49",Neutral,98,Tolerated,"33,64","16,55"
"low bq, low freq, many artifacts",UPN2_058,17,7579562,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp42Val/c.125A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),13750,145,13941,"0,0104009755",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,49",Neutral,98,Tolerated,"33,78","17,26"
"low bq, low freq, many artifacts, many samples",UPN2_041,17,7579565,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp41Val/c.122A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),16071,177,16310,"0,0108522379",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,2,Damaging,"33,46","17,05"
"low bq, low freq, many artifacts, many samples",UPN2_042,17,7579565,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp41Val/c.122A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),15209,167,15455,"0,0108055645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,2,Damaging,"33,41","16,2"
"low bq, low freq, many artifacts, many samples",UPN2_043,17,7579565,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp41Val/c.122A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),10335,116,10480,"0,0110687023",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,2,Damaging,"33,52","16,07"
"low bq, low freq, many artifacts, many samples",UPN2_044,17,7579565,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp41Val/c.122A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),3630,51,3695,"0,0138024357",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,2,Damaging,"33,21","17,2"
"low bq, low freq, many artifacts, many samples",UPN2_045,17,7579565,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp41Val/c.122A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),13952,163,14177,"0,0114974959",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,2,Damaging,"33,44","16,6"
"low bq, low freq, many artifacts, many samples",UPN2_046,17,7579565,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp41Val/c.122A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),15666,180,15926,"0,011302273",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,2,Damaging,"33,46","17,27"
"low bq, low freq, many artifacts, many samples",UPN2_047,17,7579565,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp41Val/c.122A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),22699,265,23086,"0,0114788183",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,2,Damaging,"33,49","15,59"
"low bq, low freq, many artifacts, many samples",UPN2_048,17,7579565,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp41Val/c.122A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),20623,245,20965,"0,0116861436",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,2,Damaging,"33,48","16,69"
"low bq, low freq, many artifacts, many samples",UPN2_049,17,7579565,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp41Val/c.122A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),10794,147,11001,"0,0133624216",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,2,Damaging,"33,1","15,83"
"low bq, low freq, many artifacts, many samples",UPN2_050,17,7579565,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp41Val/c.122A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),14939,177,15187,"0,0116547047",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,2,Damaging,"33,41","16,27"
"low bq, low freq, many artifacts, many samples",UPN2_051,17,7579565,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp41Val/c.122A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),11089,125,11258,"0,0111032155",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,2,Damaging,"33,43","16,42"
"low bq, low freq, many artifacts, many samples",UPN2_053,17,7579565,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp41Val/c.122A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),12608,146,12814,"0,011393788",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,2,Damaging,"33,2","16,03"
"low bq, low freq, many artifacts, many samples",UPN2_054,17,7579565,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp41Val/c.122A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),9981,116,10138,"0,011442099",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,2,Damaging,"33,43","15,77"
"low bq, low freq, many artifacts, many samples",UPN2_007,17,7579565,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp41Val/c.122A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),12077,125,12237,"0,010214922",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,2,Damaging,"33,98","16,32"
"low bq, low freq, many artifacts, many samples",UPN2_008,17,7579565,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp41Val/c.122A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),16328,168,16570,"0,0101388051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,2,Damaging,"33,91","15,25"
"low bq, low freq, many artifacts, many samples",UPN2_055,17,7579565,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp41Val/c.122A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),16317,181,16570,"0,0109233555",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,2,Damaging,"33,37","16,02"
"low bq, low freq, many artifacts, many samples",UPN2_056,17,7579565,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp41Val/c.122A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),10046,109,10185,"0,0107020128",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,2,Damaging,"33,37","16,62"
"low bq, low freq, many artifacts, many samples",UPN2_057,17,7579565,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp41Val/c.122A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),11591,132,11774,"0,0112111432",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,2,Damaging,"33,4","16,41"
"low bq, low freq, many artifacts, many samples",UPN2_058,17,7579565,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp41Val/c.122A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),13696,192,13938,"0,0137752906",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,2,Damaging,"33,44","16,68"
"low bq, low freq, many artifacts",UPN2_013,17,7579565,T,A,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp41Val/c.122A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),3087,34,3131,"0,0108591504",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,2,Damaging,"33,88","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_001,17,7579569,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met40Leu/c.118A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),4311,49,4378,"0,0111923253",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,"0,57",Tolerated,"33,82","17,04"
"low bq, low freq, many artifacts, many samples",UPN2_014,17,7579569,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met40Leu/c.118A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),7187,76,7286,"0,0104309635",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,"0,57",Tolerated,"34,2","16,53"
"low bq, low freq, many artifacts, many samples",UPN2_041,17,7579569,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met40Leu/c.118A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),16029,214,16322,"0,0131111383",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,"0,57",Tolerated,"33,44","15,5"
"low bq, low freq, many artifacts, many samples",UPN2_042,17,7579569,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met40Leu/c.118A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),15169,219,15447,"0,0141775102",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,"0,57",Tolerated,"33,46",16
"low bq, low freq, many artifacts, many samples",UPN2_043,17,7579569,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met40Leu/c.118A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),10267,143,10478,"0,0136476427",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,"0,57",Tolerated,"33,41","15,66"
"low bq, low freq, many artifacts, many samples",UPN2_044,17,7579569,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met40Leu/c.118A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),3621,60,3694,"0,0162425555",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,"0,57",Tolerated,"33,49","20,38"
"low bq, low freq, many artifacts, many samples",UPN2_005,17,7579569,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met40Leu/c.118A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),1553,23,1580,"0,014556962",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,"0,57",Tolerated,"34,16","15,91"
"low bq, low freq, many artifacts, many samples",UPN2_045,17,7579569,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met40Leu/c.118A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),13935,178,14171,"0,0125608637",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,"0,57",Tolerated,"33,53","16,6"
"low bq, low freq, many artifacts, many samples",UPN2_046,17,7579569,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met40Leu/c.118A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),15640,198,15919,"0,0124379672",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,"0,57",Tolerated,"33,52","16,33"
"low bq, low freq, many artifacts, many samples",UPN2_047,17,7579569,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met40Leu/c.118A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),22698,298,23078,"0,0129127307",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,"0,57",Tolerated,"33,46","15,58"
"low bq, low freq, many artifacts, many samples",UPN2_048,17,7579569,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met40Leu/c.118A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),20562,259,20960,"0,0123568702",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,"0,57",Tolerated,"33,45","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_035,17,7579569,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met40Leu/c.118A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),14982,152,15195,"0,0100032906",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,"0,57",Tolerated,"34,08","16,32"
"low bq, low freq, many artifacts, many samples",UPN2_049,17,7579569,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met40Leu/c.118A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),10823,134,10995,"0,0121873579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,"0,57",Tolerated,"33,43","16,43"
"low bq, low freq, many artifacts, many samples",UPN2_050,17,7579569,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met40Leu/c.118A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),14884,216,15176,"0,0142329995",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,"0,57",Tolerated,"33,49","15,93"
"low bq, low freq, many artifacts, many samples",UPN2_051,17,7579569,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met40Leu/c.118A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),11059,152,11255,"0,0135051088",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,"0,57",Tolerated,"33,43","15,71"
"low bq, low freq, many artifacts, many samples",UPN2_052,17,7579569,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met40Leu/c.118A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),8676,110,8833,"0,0124533001",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,"0,57",Tolerated,"33,65","15,94"
"low bq, low freq, many artifacts, many samples",UPN2_038,17,7579569,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met40Leu/c.118A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),12790,130,12975,"0,0100192678",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,"0,57",Tolerated,"34,18","17,3"
"low bq, low freq, many artifacts, many samples",UPN2_039,17,7579569,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met40Leu/c.118A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),21281,222,21584,"0,0102853966",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,"0,57",Tolerated,"34,22","15,73"
"low bq, low freq, many artifacts, many samples",UPN2_053,17,7579569,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met40Leu/c.118A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),12598,166,12812,"0,0129566032",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,"0,57",Tolerated,"33,49","16,29"
"low bq, low freq, many artifacts, many samples",UPN2_054,17,7579569,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met40Leu/c.118A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),9949,126,10131,"0,0124370743",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,"0,57",Tolerated,"33,5","16,3"
"low bq, low freq, many artifacts, many samples",UPN2_007,17,7579569,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met40Leu/c.118A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),12048,137,12236,"0,0111964694",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,"0,57",Tolerated,"33,71","16,12"
"low bq, low freq, many artifacts, many samples",UPN2_008,17,7579569,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met40Leu/c.118A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),16348,166,16580,"0,0100120627",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,"0,57",Tolerated,"33,8","16,54"
"low bq, low freq, many artifacts, many samples",UPN2_009,17,7579569,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met40Leu/c.118A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),13751,140,13936,"0,0100459242",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,"0,57",Tolerated,"33,73","15,49"
"low bq, low freq, many artifacts, many samples",UPN2_011,17,7579569,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met40Leu/c.118A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),11176,142,11352,"0,012508809",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,"0,57",Tolerated,"33,72","15,8"
"low bq, low freq, many artifacts, many samples",UPN2_055,17,7579569,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met40Leu/c.118A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),16266,211,16566,"0,0127369311",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,"0,57",Tolerated,"33,39","16,35"
"low bq, low freq, many artifacts, many samples",UPN2_056,17,7579569,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met40Leu/c.118A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),10009,125,10180,"0,0122789784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,"0,57",Tolerated,"33,43","16,21"
"low bq, low freq, many artifacts, many samples",UPN2_057,17,7579569,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met40Leu/c.118A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),11537,173,11768,"0,0147008838",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,"0,57",Tolerated,"33,44","15,98"
"low bq, low freq, many artifacts, many samples",UPN2_058,17,7579569,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met40Leu/c.118A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),13686,200,13931,"0,0143564712",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,"0,57",Tolerated,"33,41","16,47"
"low bq, low freq, many artifacts, many samples",UPN2_012,17,7579569,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met40Leu/c.118A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),6130,87,6232,"0,0139602054",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,"0,57",Tolerated,"33,69","16,01"
"low bq, low freq, many artifacts",UPN2_040,17,7579569,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met40Leu/c.118A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),15194,162,15419,"0,0105065179",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,"0,57",Tolerated,"34,16","16,55"
"low bq, low freq, many artifacts, many samples",UPN2_004,17,7579573,T,A,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln38His/c.114A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),1773,21,1800,"0,0116666667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,219,Tolerated,"34,03","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_042,17,7579573,T,A,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln38His/c.114A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),15197,169,15441,"0,010944887",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,219,Tolerated,"33,76","17,32"
"low bq, low freq, many artifacts, many samples",UPN2_043,17,7579573,T,A,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln38His/c.114A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),10302,131,10476,"0,0125047728",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,219,Tolerated,"33,76","17,15"
"low bq, low freq, many artifacts, many samples",UPN2_048,17,7579573,T,A,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln38His/c.114A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),20610,221,20949,"0,0105494296",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,219,Tolerated,"33,78","16,97"
"low bq, low freq, many artifacts, many samples",UPN2_049,17,7579573,T,A,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln38His/c.114A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),10806,133,10992,"0,0120997089",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,219,Tolerated,"33,54","17,03"
"low bq, low freq, many artifacts, many samples",UPN2_050,17,7579573,T,A,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln38His/c.114A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),14914,185,15171,"0,0121943181",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,219,Tolerated,"33,7","17,54"
"low bq, low freq, many artifacts, many samples",UPN2_052,17,7579573,T,A,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln38His/c.114A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),8714,93,8828,"0,0105346624",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,219,Tolerated,"33,81","17,63"
"low bq, low freq, many artifacts, many samples",UPN2_053,17,7579573,T,A,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln38His/c.114A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),12627,129,12803,"0,0100757635",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,219,Tolerated,"33,66","16,29"
"low bq, low freq, many artifacts, many samples",UPN2_055,17,7579573,T,A,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln38His/c.114A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),16333,168,16563,"0,01014309",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,219,Tolerated,"33,71","16,48"
"low bq, low freq, many artifacts, many samples",UPN2_056,17,7579573,T,A,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln38His/c.114A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),10029,115,10175,"0,0113022113",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,219,Tolerated,"33,73","17,65"
"low bq, low freq, many artifacts, many samples",UPN2_058,17,7579573,T,A,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln38His/c.114A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),13715,167,13927,"0,0119910964",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,219,Tolerated,"33,77","16,5"
"low bq, low freq, many artifacts",UPN2_060,17,7579573,T,A,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln38His/c.114A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),3000,32,3041,"0,0105228543",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,219,Tolerated,"34,1","22,66"
"low bq, low freq, many artifacts, many samples",UPN2_017,17,7579574,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln38Leu/c.113A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),2882,33,2925,"0,0112820513",0,0,0,0,1,0,0,0,1,NO,NO,COSM307330,urinary_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,243,Tolerated,"34,09","18,39"
"low bq, low freq, many artifacts, many samples",UPN2_022,17,7579574,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln38Leu/c.113A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),8133,85,8247,"0,0103067782",0,0,0,0,1,0,0,0,1,NO,NO,COSM307330,urinary_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,243,Tolerated,"33,94","17,64"
"low bq, low freq, many artifacts, many samples",UPN2_041,17,7579574,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln38Leu/c.113A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),16037,218,16313,"0,0133635751",0,0,0,0,1,0,0,0,1,NO,NO,COSM307330,urinary_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,243,Tolerated,"33,02","18,61"
"low bq, low freq, many artifacts, many samples",UPN2_024,17,7579574,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln38Leu/c.113A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),4074,45,4134,"0,0108853411",0,0,0,0,1,0,0,0,1,NO,NO,COSM307330,urinary_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,243,Tolerated,"33,98","20,42"
"low bq, low freq, many artifacts, many samples",UPN2_025,17,7579574,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln38Leu/c.113A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),10344,113,10501,"0,0107608799",0,0,0,0,1,0,0,0,1,NO,NO,COSM307330,urinary_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,243,Tolerated,"33,95","18,28"
"low bq, low freq, many artifacts, many samples",UPN2_042,17,7579574,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln38Leu/c.113A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),15164,212,15439,"0,0137314593",0,0,0,0,1,0,0,0,1,NO,NO,COSM307330,urinary_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,243,Tolerated,"33,08","18,47"
"low bq, low freq, many artifacts, many samples",UPN2_043,17,7579574,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln38Leu/c.113A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),10261,164,10476,"0,0156548301",0,0,0,0,1,0,0,0,1,NO,NO,COSM307330,urinary_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,243,Tolerated,"32,99","17,98"
"low bq, low freq, many artifacts, many samples",UPN2_044,17,7579574,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln38Leu/c.113A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),3630,57,3693,"0,015434606",0,0,0,0,1,0,0,0,1,NO,NO,COSM307330,urinary_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,243,Tolerated,"33,15","19,33"
"low bq, low freq, many artifacts, many samples",UPN2_045,17,7579574,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln38Leu/c.113A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),13895,193,14166,"0,0136241705",0,0,0,0,1,0,0,0,1,NO,NO,COSM307330,urinary_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,243,Tolerated,"33,04","18,32"
"low bq, low freq, many artifacts, many samples",UPN2_046,17,7579574,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln38Leu/c.113A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),15648,199,15913,"0,0125054986",0,0,0,0,1,0,0,0,1,NO,NO,COSM307330,urinary_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,243,Tolerated,"33,12","18,78"
"low bq, low freq, many artifacts, many samples",UPN2_034,17,7579574,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln38Leu/c.113A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),2576,31,2617,"0,0118456248",0,0,0,0,1,0,0,0,1,NO,NO,COSM307330,urinary_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,243,Tolerated,"34,18","20,58"
"low bq, low freq, many artifacts, many samples",UPN2_047,17,7579574,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln38Leu/c.113A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),22631,348,23075,"0,0150812568",0,0,0,0,1,0,0,0,1,NO,NO,COSM307330,urinary_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,243,Tolerated,"33,04","18,53"
"low bq, low freq, many artifacts, many samples",UPN2_048,17,7579574,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln38Leu/c.113A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),20600,273,20947,"0,0130328925",0,0,0,0,1,0,0,0,1,NO,NO,COSM307330,urinary_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,243,Tolerated,"33,02","18,71"
"low bq, low freq, many artifacts, many samples",UPN2_049,17,7579574,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln38Leu/c.113A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),10752,188,10991,"0,017104904",0,0,0,0,1,0,0,0,1,NO,NO,COSM307330,urinary_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,243,Tolerated,"32,97","18,88"
"low bq, low freq, many artifacts, many samples",UPN2_050,17,7579574,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln38Leu/c.113A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),14899,206,15170,"0,0135794331",0,0,0,0,1,0,0,0,1,NO,NO,COSM307330,urinary_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,243,Tolerated,"33,19","18,07"
"low bq, low freq, many artifacts, many samples",UPN2_051,17,7579574,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln38Leu/c.113A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),11031,160,11249,"0,0142234865",0,0,0,0,1,0,0,0,1,NO,NO,COSM307330,urinary_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,243,Tolerated,"32,96","19,08"
"low bq, low freq, many artifacts, many samples",UPN2_052,17,7579574,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln38Leu/c.113A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),8673,120,8828,"0,0135931128",0,0,0,0,1,0,0,0,1,NO,NO,COSM307330,urinary_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,243,Tolerated,"33,28","18,1"
"low bq, low freq, many artifacts, many samples",UPN2_053,17,7579574,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln38Leu/c.113A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),12593,162,12803,"0,0126532844",0,0,0,0,1,0,0,0,1,NO,NO,COSM307330,urinary_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,243,Tolerated,"33,16","18,01"
"low bq, low freq, many artifacts, many samples",UPN2_054,17,7579574,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln38Leu/c.113A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),9956,132,10127,"0,0130344623",0,0,0,0,1,0,0,0,1,NO,NO,COSM307330,urinary_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,243,Tolerated,"33,12","17,23"
"low bq, low freq, many artifacts, many samples",UPN2_009,17,7579574,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln38Leu/c.113A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),13762,144,13938,"0,0103314679",0,0,0,0,1,0,0,0,1,NO,NO,COSM307330,urinary_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,243,Tolerated,"33,61","17,38"
"low bq, low freq, many artifacts, many samples",UPN2_055,17,7579574,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln38Leu/c.113A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),16276,226,16561,"0,0136465189",0,0,0,0,1,0,0,0,1,NO,NO,COSM307330,urinary_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,243,Tolerated,"33,08","18,35"
"low bq, low freq, many artifacts, many samples",UPN2_056,17,7579574,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln38Leu/c.113A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),9979,153,10173,"0,0150398113",0,0,0,0,1,0,0,0,1,NO,NO,COSM307330,urinary_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,243,Tolerated,"33,07","18,36"
"low bq, low freq, many artifacts, many samples",UPN2_057,17,7579574,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln38Leu/c.113A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),11567,153,11757,"0,0130135239",0,0,0,0,1,0,0,0,1,NO,NO,COSM307330,urinary_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,243,Tolerated,"33,01","18,82"
"low bq, low freq, many artifacts, many samples",UPN2_058,17,7579574,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln38Leu/c.113A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),13671,213,13927,"0,0152940332",0,0,0,0,1,0,0,0,1,NO,NO,COSM307330,urinary_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,243,Tolerated,"33,01","18,68"
"low bq, low freq, many artifacts",UPN2_076,17,7579574,T,A,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln38Leu/c.113A>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),2146,23,2176,"0,0105698529",0,0,0,0,1,0,0,0,1,NO,NO,COSM307330,urinary_tract,1,NO,NO,NO,NO,NO,NO,"-0,8",Neutral,243,Tolerated,"33,64","19,35"
"inspected, many artifacts",UPN2_097,17,7579575,G,C,missense_variant(MODERATE|MISSENSE|Caa/Gaa|p.Gln38Glu/c.112C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),7570,173,7771,"0,0222622571",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,15",Neutral,1,Tolerated,"33,9","30,88"
"low freq, many artifacts",UPN2_105,17,7579575,G,C,missense_variant(MODERATE|MISSENSE|Caa/Gaa|p.Gln38Glu/c.112C>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),6080,64,6168,"0,0103761349",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,15",Neutral,1,Tolerated,"33,74","28,69"
"low bq, low freq, many artifacts, many samples",UPN2_044,17,7579578,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser37Ala/c.109T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),3624,38,3693,"0,0102897373",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,24,Damaging,"29,5","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_060,17,7579578,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser37Ala/c.109T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),2992,31,3039,"0,0102007239",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,24,Damaging,"30,29","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_071,17,7579578,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser37Ala/c.109T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),3877,41,3937,"0,0104140208",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,24,Damaging,"30,41","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_072,17,7579578,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser37Ala/c.109T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),4425,48,4497,"0,0106737825",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,24,Damaging,"30,35","15,52"
"low bq, low freq, many artifacts, many samples",UPN2_075,17,7579578,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser37Ala/c.109T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),5171,59,5256,"0,0112252664",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,24,Damaging,"30,66","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_079,17,7579578,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser37Ala/c.109T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),2061,24,2092,"0,0114722753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,24,Damaging,"30,55","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_080,17,7579578,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser37Ala/c.109T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),4103,48,4165,"0,0115246098",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,24,Damaging,"30,49","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_083,17,7579578,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser37Ala/c.109T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),2025,21,2059,"0,0101991258",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,24,Damaging,"30,19","14,33"
"low bq, low freq, many artifacts",UPN2_084,17,7579578,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser37Ala/c.109T>G|393|TP53|protein_coding|CODING|ENST00000269305|4|C),2750,28,2789,"0,0100394407",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,24,Damaging,"30,3","14,46"
"low freq, many artifacts",UPN2_044,17,7579582,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu35Phe/c.105G>T|393|TP53|protein_coding|CODING|ENST00000269305|4|A),3635,46,3693,"0,0124559978",0,0,0,0,1,0,0,1,2,NO,NO,COSM46160,"lung, pancreas","1, 1",NO,rs121912661,YES,NO,NO,NO,"-0,46",Neutral,"0,21",Tolerated,"34,31",30
"low freq, many artifacts",UPN2_006,17,7579711,T,A,missense_variant(MODERATE|MISSENSE|Aac/Tac|p.Asn29Tyr/c.85A>T|393|TP53|protein_coding|CODING|ENST00000269305|3|A),4697,53,4757,"0,0111414757",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,2",Neutral,"0,008",Damaging,"34,92","35,17"
"low freq, many artifacts",UPN2_010,17,7579714,C,T,missense_variant(MODERATE|MISSENSE|Gaa/Aaa|p.Glu28Lys/c.82G>A|393|TP53|protein_coding|CODING|ENST00000269305|3|T),15472,162,15652,"0,010350115",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,5",Neutral,"0,064",Tolerated,"33,74","31,89"
"low freq, many artifacts",UPN2_079,17,7579714,C,T,missense_variant(MODERATE|MISSENSE|Gaa/Aaa|p.Glu28Lys/c.82G>A|393|TP53|protein_coding|CODING|ENST00000269305|3|T),3040,32,3079,"0,0103929847",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,5",Neutral,"0,064",Tolerated,"33,72","31,12"
"low freq, many artifacts",UPN2_008,17,7579716,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro27His/c.80C>A|393|TP53|protein_coding|CODING|ENST00000269305|3|T),25935,283,26261,"0,0107764365",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,"0,001",Damaging,"33,97","30,66"
"low freq, many artifacts",UPN2_062,17,7579716,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro27His/c.80C>A|393|TP53|protein_coding|CODING|ENST00000269305|3|T),8289,95,8398,"0,0113122172",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,"0,001",Damaging,"34,07","30,55"
"low freq, many artifacts, many samples",UPN2_063,17,7579716,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro27His/c.80C>A|393|TP53|protein_coding|CODING|ENST00000269305|3|T),2326,52,2385,"0,021802935",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"33,75","30,62"
"low freq, many artifacts, many samples",UPN2_071,17,7579716,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro27His/c.80C>A|393|TP53|protein_coding|CODING|ENST00000269305|3|T),5307,62,5373,"0,0115391774",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"34,14","31,02"
"low freq, many artifacts",UPN2_082,17,7579716,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro27His/c.80C>A|393|TP53|protein_coding|CODING|ENST00000269305|3|T),1941,21,1963,"0,0106979114",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,"0,001",Damaging,"34,05","28,76"
"low freq, many artifacts",UPN2_083,17,7579716,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro27His/c.80C>A|393|TP53|protein_coding|CODING|ENST00000269305|3|T),2960,33,2997,"0,011011011",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,"0,001",Damaging,"34,01","31,24"
"low freq, many artifacts, many samples",UPN2_084,17,7579716,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro27His/c.80C>A|393|TP53|protein_coding|CODING|ENST00000269305|3|T),4199,44,4261,"0,0103262145",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"33,84","29,55"
"low freq, many artifacts",UPN2_111,17,7579716,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro27His/c.80C>A|393|TP53|protein_coding|CODING|ENST00000269305|3|T),8810,101,8930,"0,0113101904",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,"0,001",Damaging,"34,6","30,75"
"low bq, low freq, many artifacts, many samples",UPN2_064,17,7579838,C,G,splice_donor_variant+intron_variant(HIGH|||c.74+1G>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1772,20,1794,"0,011148272",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,2",15
"low bq, low freq, many artifacts",UPN2_075,17,7579838,C,G,splice_donor_variant+intron_variant(HIGH|||c.74+1G>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),4247,43,4297,"0,0100069816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,07",14
"low bq, low freq, many artifacts, many samples",UPN2_001,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),4249,46,4318,"0,0106530801",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"31,69","18,8"
"low bq, low freq, many artifacts, many samples",UPN2_015,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),9146,99,9283,"0,0106646558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"31,61","16,43"
"low bq, low freq, many artifacts, many samples",UPN2_016,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3909,50,3970,"0,0125944584",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"31,26","15,98"
"low bq, low freq, many artifacts, many samples",UPN2_017,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2018,34,2065,"0,016464891",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"30,98","18,88"
"low bq, low freq, many artifacts, many samples",UPN2_018,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3833,44,3896,"0,0112936345",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"30,9","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_020,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3302,41,3369,"0,0121697833",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"31,52","19,41"
"low bq, low freq, many artifacts, many samples",UPN2_021,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),5120,56,5212,"0,0107444359",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"31,5","18,23"
"low bq, low freq, many artifacts, many samples",UPN2_023,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6533,70,6634,"0,0105517033",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"31,65","17,91"
"low bq, low freq, many artifacts, many samples",UPN2_027,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),8790,99,8921,"0,0110974106",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"31,52","18,36"
"low bq, low freq, many artifacts, many samples",UPN2_042,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),7904,119,8083,"0,0147222566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"31,01","16,61"
"low bq, low freq, many artifacts, many samples",UPN2_043,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),4578,55,4660,"0,0118025751",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"30,92","16,27"
"low bq, low freq, many artifacts, many samples",UPN2_044,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1858,38,1911,"0,019884877",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"30,11","15,74"
"low bq, low freq, many artifacts, many samples",UPN2_029,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6038,63,6141,"0,0102589155",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"31,61","16,14"
"low bq, low freq, many artifacts, many samples",UPN2_031,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3963,46,4036,"0,0113974232",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"31,04","16,11"
"low bq, low freq, many artifacts, many samples",UPN2_005,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1715,24,1744,"0,0137614679",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"31,5","17,5"
"low bq, low freq, many artifacts, many samples",UPN2_045,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3420,76,3517,"0,0216093261",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"30,03","16,39"
"low bq, low freq, many artifacts, many samples",UPN2_046,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),9090,130,9289,"0,0139950479",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"31,03","18,27"
"low bq, low freq, many artifacts, many samples",UPN2_033,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),4836,54,4910,"0,0109979633",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"31,09","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_047,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),8258,151,8463,"0,0178423727",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"30,95","20,05"
"low bq, low freq, many artifacts, many samples",UPN2_048,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3319,63,3404,"0,0185076381",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"31,16","17,22"
"low bq, low freq, many artifacts, many samples",UPN2_036,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),21616,282,22004,"0,0128158517",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"31,09","18,15"
"low bq, low freq, many artifacts, many samples",UPN2_006,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3762,42,3825,"0,0109803922",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"31,52","18,62"
"low bq, low freq, many artifacts, many samples",UPN2_049,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6418,126,6583,"0,0191402096",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"30,11","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_050,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6101,111,6258,"0,0177372963",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"30,77","18,39"
"low bq, low freq, many artifacts, many samples",UPN2_037,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),10349,118,10505,"0,0112327463",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"31,58","19,25"
"low bq, low freq, many artifacts, many samples",UPN2_051,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6982,113,7150,"0,0158041958",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"30,8","15,99"
"low bq, low freq, many artifacts, many samples",UPN2_052,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3921,74,4035,"0,0183395291",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"31,16","19,35"
"low bq, low freq, many artifacts, many samples",UPN2_038,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),12328,145,12534,"0,0115685336",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"31,57","17,92"
"low bq, low freq, many artifacts, many samples",UPN2_039,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),18721,217,19053,"0,0113892825",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"31,02","16,11"
"low bq, low freq, many artifacts, many samples",UPN2_053,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),9098,164,9359,"0,0175232397",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"30,64","16,47"
"low bq, low freq, many artifacts, many samples",UPN2_054,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6553,118,6700,"0,0176119403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"31,01","18,47"
"low bq, low freq, many artifacts, many samples",UPN2_007,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),13292,161,13521,"0,0119074033",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"31,48","16,34"
"low bq, low freq, many artifacts, many samples",UPN2_008,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),18257,233,18591,"0,012532946",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"31,36","18,55"
"low bq, low freq, many artifacts, many samples",UPN2_009,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),14192,164,14424,"0,011369939",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"31,24","16,13"
"low bq, low freq, many artifacts, many samples",UPN2_010,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),11166,135,11371,"0,0118723067",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"31,13","15,58"
"low bq, low freq, many artifacts, many samples",UPN2_011,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),9942,115,10106,"0,0113793786",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"31,53","16,87"
"low bq, low freq, many artifacts, many samples",UPN2_055,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),7777,126,7936,"0,0158770161",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"31,21","17,2"
"low bq, low freq, many artifacts, many samples",UPN2_056,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3905,71,3990,"0,0177944862",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"30,76","16,75"
"low bq, low freq, many artifacts, many samples",UPN2_057,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6849,124,7029,"0,0176412007",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"30,52","16,42"
"low bq, low freq, many artifacts, many samples",UPN2_058,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),14702,248,15004,"0,0165289256",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"31,12","17,61"
"low bq, low freq, many artifacts, many samples",UPN2_012,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6145,74,6254,"0,0118324272",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"31,4","15,97"
"low bq, low freq, many artifacts, many samples",UPN2_060,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1834,26,1871,"0,0138963121",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"29,41","18,23"
"low bq, low freq, many artifacts, many samples",UPN2_040,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),7977,106,8125,"0,0130461538",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"31,21","17,75"
"low bq, low freq, many artifacts, many samples",UPN2_013,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3658,48,3725,"0,012885906",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"31,54","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_061,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2804,36,2862,"0,0125786164",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"29,37","16,11"
"low bq, low freq, many artifacts, many samples",UPN2_062,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),4619,54,4713,"0,0114576703",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"29,29","15,94"
"low bq, low freq, many artifacts, many samples",UPN2_063,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1622,24,1669,"0,0143798682",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"28,76","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_069,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1712,26,1755,"0,0148148148",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"29,03","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_071,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2618,31,2668,"0,0116191904",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"28,9","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_076,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1878,21,1924,"0,0109147609",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"28,95","19,9"
"low bq, low freq, many artifacts, many samples",UPN2_077,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1879,25,1929,"0,0129600829",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"29,75","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_079,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1814,22,1857,"0,0118470652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"29,5",14
"low bq, low freq, many artifacts, many samples",UPN2_083,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1710,30,1748,"0,0171624714",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"28,95","17,1"
"low bq, low freq, many artifacts, many samples",UPN2_084,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2699,31,2761,"0,011227816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"29,38","16,87"
"low bq, low freq, many artifacts",UPN2_110,17,7579839,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu25Gln/c.74T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),4191,46,4263,"0,0107905231",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,11,Damaging,"31,24","16,59"
"low freq, many artifacts",UPN2_048,17,7579840,G,C,missense_variant+splice_region_variant(MODERATE|MISSENSE|Cta/Gta|p.Leu25Val/c.73C>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),3355,42,3408,"0,0123239437",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,47",Neutral,"0,053",Tolerated,"32,69","29,5"
"low bq, low freq, many artifacts, many samples",UPN2_059,17,7579841,T,G,missense_variant+splice_region_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys24Asn/c.72A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1563,25,1612,"0,0155086849",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,39",Neutral,475,Tolerated,"29,78",14
"low bq, low freq, many artifacts, many samples",UPN2_060,17,7579841,T,G,missense_variant+splice_region_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys24Asn/c.72A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1835,20,1871,"0,0106894709",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,39",Neutral,475,Tolerated,"29,32","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_061,17,7579841,T,G,missense_variant+splice_region_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys24Asn/c.72A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),2806,37,2869,"0,0128964796",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,39",Neutral,475,Tolerated,"29,2","18,78"
"low bq, low freq, many artifacts, many samples",UPN2_062,17,7579841,T,G,missense_variant+splice_region_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys24Asn/c.72A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),4613,66,4715,"0,0139978791",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,39",Neutral,475,Tolerated,"28,83","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_063,17,7579841,T,G,missense_variant+splice_region_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys24Asn/c.72A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1639,28,1673,"0,0167364017",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,39",Neutral,475,Tolerated,"28,09","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_064,17,7579841,T,G,missense_variant+splice_region_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys24Asn/c.72A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1746,30,1797,"0,0166944908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,39",Neutral,475,Tolerated,"28,95","18,53"
"low bq, low freq, many artifacts, many samples",UPN2_069,17,7579841,T,G,missense_variant+splice_region_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys24Asn/c.72A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1723,22,1757,"0,0125213432",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,39",Neutral,475,Tolerated,"28,6","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_070,17,7579841,T,G,missense_variant+splice_region_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys24Asn/c.72A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1483,25,1521,"0,0164365549",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,39",Neutral,475,Tolerated,"29,06","19,52"
"low bq, low freq, many artifacts, many samples",UPN2_071,17,7579841,T,G,missense_variant+splice_region_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys24Asn/c.72A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),2624,28,2672,"0,0104790419",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,39",Neutral,475,Tolerated,"28,61","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_072,17,7579841,T,G,missense_variant+splice_region_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys24Asn/c.72A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),3535,50,3620,"0,0138121547",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,39",Neutral,475,Tolerated,"28,97","16,84"
"low bq, low freq, many artifacts, many samples",UPN2_073,17,7579841,T,G,missense_variant+splice_region_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys24Asn/c.72A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),2137,27,2181,"0,0123796424",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,39",Neutral,475,Tolerated,"29,62","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_076,17,7579841,T,G,missense_variant+splice_region_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys24Asn/c.72A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1895,20,1927,"0,0103788272",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,39",Neutral,475,Tolerated,"28,65","15,75"
"low bq, low freq, many artifacts, many samples",UPN2_077,17,7579841,T,G,missense_variant+splice_region_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys24Asn/c.72A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1895,23,1930,"0,0119170984",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,39",Neutral,475,Tolerated,"29,05","18,13"
"low bq, low freq, many artifacts, many samples",UPN2_078,17,7579841,T,G,missense_variant+splice_region_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys24Asn/c.72A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),3728,44,3788,"0,0116156283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,39",Neutral,475,Tolerated,"29,16","15,82"
"low bq, low freq, many artifacts, many samples",UPN2_080,17,7579841,T,G,missense_variant+splice_region_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys24Asn/c.72A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),3758,53,3844,"0,0137877211",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,39",Neutral,475,Tolerated,"29,1","17,09"
"low bq, low freq, many artifacts, many samples",UPN2_081,17,7579841,T,G,missense_variant+splice_region_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys24Asn/c.72A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),5355,57,5463,"0,0104338276",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,39",Neutral,475,Tolerated,"29,36","15,7"
"low bq, low freq, many artifacts",UPN2_087,17,7579841,T,G,missense_variant+splice_region_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys24Asn/c.72A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1422,22,1458,"0,0150891632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,39",Neutral,475,Tolerated,"28,86","17,32"
"low freq, many artifacts",UPN2_048,17,7579842,T,C,missense_variant(MODERATE|MISSENSE|aAa/aGa|p.Lys24Arg/c.71A>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),3358,36,3409,"0,0105602816",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,117",Tolerated,"30,84","31,69"
"low bq, low freq, many artifacts",UPN2_079,17,7579842,T,G,missense_variant(MODERATE|MISSENSE|aAa/aCa|p.Lys24Thr/c.71A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1824,21,1858,"0,0113024758",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,139,Tolerated,"29,22",14
"low freq, many artifacts",UPN2_052,17,7579843,TC,T,frameshift_variant(HIGH||tgg/|p.Trp23fs/c.69delG|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3980,41,4041,"0,0101460035",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,29",NA
"low freq, many artifacts",UPN2_006,17,7579844,C,T,stop_gained(HIGH|NONSENSE|tgG/tgA|p.Trp23*/c.69G>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3761,53,3829,"0,0138417341",0,0,0,0,1,0,0,1,2,NO,NO,"COSM4556689, COSM4556688, COSM4556690, COSM4556691, COSM4556687, COSM4556692",skin,6,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,21","30,47"
"low bq, low freq, many artifacts, many samples",UPN2_069,17,7579845,C,G,missense_variant(MODERATE|MISSENSE|tGg/tCg|p.Trp23Ser/c.68G>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1731,23,1760,"0,0130681818",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,71",Deleterious,0,Damaging,"27,14",14
"low bq, low freq, many artifacts, many samples",UPN2_072,17,7579845,C,G,missense_variant(MODERATE|MISSENSE|tGg/tCg|p.Trp23Ser/c.68G>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),3567,37,3622,"0,0102153506",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,71",Deleterious,0,Damaging,"27,33","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_083,17,7579845,C,G,missense_variant(MODERATE|MISSENSE|tGg/tCg|p.Trp23Ser/c.68G>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1730,20,1754,"0,0114025086",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,71",Deleterious,0,Damaging,"27,41","14,65"
"low bq, low freq, many artifacts",UPN2_084,17,7579845,C,G,missense_variant(MODERATE|MISSENSE|tGg/tCg|p.Trp23Ser/c.68G>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),2722,33,2767,"0,0119262739",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-7,71",Deleterious,0,Damaging,"27,33",14
"low bq, low freq, many artifacts, many samples",UPN2_014,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6319,79,6423,"0,0122995485",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"30,82","19,22"
"low bq, low freq, many artifacts, many samples",UPN2_015,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),9135,102,9282,"0,010989011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"30,45","17,55"
"low bq, low freq, many artifacts, many samples",UPN2_016,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3906,50,3970,"0,0125944584",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"30,42","18,44"
"low bq, low freq, many artifacts, many samples",UPN2_017,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2034,31,2065,"0,0150121065",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"30,04","16,71"
"low bq, low freq, many artifacts, many samples",UPN2_018,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3856,41,3903,"0,0105047399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"30,1","15,73"
"low bq, low freq, many artifacts, many samples",UPN2_021,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),5130,72,5214,"0,0138089758",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"30,73","16,75"
"low bq, low freq, many artifacts, many samples",UPN2_002,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),4589,84,4692,"0,0179028133",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"30,57","17,63"
"low bq, low freq, many artifacts, many samples",UPN2_022,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6845,79,6949,"0,0113685422",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"30,82","17,29"
"low bq, low freq, many artifacts, many samples",UPN2_024,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2613,28,2651,"0,0105620521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"30,44","17,14"
"low bq, low freq, many artifacts, many samples",UPN2_025,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),8481,98,8606,"0,0113874041",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"30,77","15,57"
"low bq, low freq, many artifacts, many samples",UPN2_026,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),7255,82,7362,"0,0111382776",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"30,58","16,44"
"low bq, low freq, many artifacts, many samples",UPN2_027,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),8796,104,8923,"0,0116552729",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"30,61","16,73"
"low bq, low freq, many artifacts, many samples",UPN2_042,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),7912,143,8093,"0,017669591",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"30,55","16,12"
"low bq, low freq, many artifacts, many samples",UPN2_028,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6840,86,6955,"0,0123652049",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"30,67","17,51"
"low bq, low freq, many artifacts, many samples",UPN2_043,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),4593,61,4669,"0,0130648961",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"30,55","16,89"
"low bq, low freq, many artifacts, many samples",UPN2_044,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1866,42,1915,"0,0219321149",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"29,43","15,88"
"low bq, low freq, many artifacts, many samples",UPN2_029,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6054,75,6143,"0,0122090184",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"30,74","19,21"
"low bq, low freq, many artifacts, many samples",UPN2_030,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6723,76,6824,"0,011137163",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"30,16","16,63"
"low bq, low freq, many artifacts, many samples",UPN2_031,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3980,49,4038,"0,0121347202",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"30,41","15,31"
"low bq, low freq, many artifacts, many samples",UPN2_005,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1719,26,1746,"0,0148911798",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"31,01","16,88"
"low bq, low freq, many artifacts, many samples",UPN2_045,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3446,63,3529,"0,0178520827",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"29,67","19,05"
"low bq, low freq, many artifacts, many samples",UPN2_032,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3011,40,3063,"0,0130590924",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"30,9","19,4"
"low bq, low freq, many artifacts, many samples",UPN2_046,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),9125,142,9304,"0,0152622528",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"30,46","18,39"
"low bq, low freq, many artifacts, many samples",UPN2_033,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),4830,62,4916,"0,0126118796",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"30,62","17,16"
"low bq, low freq, many artifacts, many samples",UPN2_034,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1681,21,1712,"0,0122663551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"30,16","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_047,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),8266,144,8477,"0,0169871417",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"30,42","16,67"
"low bq, low freq, many artifacts, many samples",UPN2_048,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3334,60,3412,"0,0175849941",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"30,44","15,4"
"low bq, low freq, many artifacts, many samples",UPN2_036,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),21693,279,22020,"0,0126702997",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"30,35","16,64"
"low bq, low freq, many artifacts, many samples",UPN2_006,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3757,62,3830,"0,0161879896",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"31,01","17,84"
"low bq, low freq, many artifacts, many samples",UPN2_049,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6428,138,6597,"0,0209185994",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"29,8","16,63"
"low bq, low freq, many artifacts, many samples",UPN2_050,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6127,106,6270,"0,0169059011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"30,45","17,18"
"low bq, low freq, many artifacts, many samples",UPN2_051,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6994,130,7167,"0,0181386912",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"30,15","18,05"
"low bq, low freq, many artifacts, many samples",UPN2_052,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3979,48,4041,"0,011878248",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"30,49","17,1"
"low bq, low freq, many artifacts, many samples",UPN2_038,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),12357,144,12536,"0,0114869177",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"30,68","18,33"
"low bq, low freq, many artifacts, many samples",UPN2_039,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),18777,256,19076,"0,0134200042",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"30,13","16,64"
"low bq, low freq, many artifacts, many samples",UPN2_053,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),9162,157,9379,"0,0167395245",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"29,98","18,76"
"low bq, low freq, many artifacts, many samples",UPN2_054,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6595,83,6708,"0,0123732856",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"30,46","15,89"
"low bq, low freq, many artifacts, many samples",UPN2_007,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),13305,178,13530,"0,0131559497",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"31,12","16,48"
"low bq, low freq, many artifacts, many samples",UPN2_008,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),18331,222,18617,"0,0119245851",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"30,81","16,45"
"low bq, low freq, many artifacts, many samples",UPN2_009,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),14211,163,14437,"0,0112904343",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"30,87","17,27"
"low bq, low freq, many artifacts, many samples",UPN2_010,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),11224,115,11394,"0,0100930314",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"30,86","17,2"
"low bq, low freq, many artifacts, many samples",UPN2_011,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),9976,113,10120,"0,0111660079",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"30,95","16,13"
"low bq, low freq, many artifacts, many samples",UPN2_055,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),7790,113,7944,"0,014224572",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"30,59","17,12"
"low bq, low freq, many artifacts, many samples",UPN2_056,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3916,55,3998,"0,0137568784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"30,42","17,53"
"low bq, low freq, many artifacts, many samples",UPN2_057,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6891,107,7037,"0,0152053432",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"30,03","15,57"
"low bq, low freq, many artifacts, many samples",UPN2_058,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),14687,286,15033,"0,0190248121",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"30,49","18,56"
"low bq, low freq, many artifacts, many samples",UPN2_059,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1588,21,1615,"0,013003096",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"29,2","19,86"
"low bq, low freq, many artifacts, many samples",UPN2_012,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6147,85,6260,"0,0135782748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"31,19","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_040,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),7986,115,8131,"0,0141434018",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"30,11","17,52"
"low bq, low freq, many artifacts, many samples",UPN2_013,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3687,39,3731,"0,0104529617",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"31,3","15,77"
"low bq, low freq, many artifacts, many samples",UPN2_061,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2790,40,2870,"0,0139372822",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"29,32","18,42"
"low bq, low freq, many artifacts, many samples",UPN2_062,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),4628,53,4718,"0,0112335735",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"28,9","17,66"
"low bq, low freq, many artifacts, many samples",UPN2_064,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1767,20,1798,"0,0111234705",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"28,9",16
"low bq, low freq, many artifacts, many samples",UPN2_069,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1720,27,1760,"0,0153409091",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"28,83","17,93"
"low bq, low freq, many artifacts, many samples",UPN2_073,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2131,29,2183,"0,0132844709",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"29,51","19,14"
"low bq, low freq, many artifacts, many samples",UPN2_075,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),4208,55,4306,"0,0127728751",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"29,54","19,22"
"low bq, low freq, many artifacts, many samples",UPN2_076,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1889,24,1927,"0,0124545926",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"28,74","17,29"
"low bq, low freq, many artifacts, many samples",UPN2_078,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3708,47,3789,"0,0124043283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"29,15","17,72"
"low bq, low freq, many artifacts",UPN2_079,17,7579846,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp23Arg/c.67T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1828,21,1858,"0,0113024758",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,25",Deleterious,0,Damaging,"29,17","15,9"
"low bq, low freq, many artifacts, many samples",UPN2_063,17,7579848,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu22Arg/c.65T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),1604,33,1673,"0,0197250448",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,0,Damaging,"27,84","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_064,17,7579848,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu22Arg/c.65T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),1764,20,1798,"0,0111234705",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,0,Damaging,"28,88","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_069,17,7579848,A,C,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu22Arg/c.65T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),1727,20,1762,"0,0113507378",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,0,Damaging,"28,76","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_001,17,7579848,A,T,missense_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu22Gln/c.65T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),4242,59,4322,"0,0136510875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,08",Deleterious,0,Damaging,"30,82","17,07"
"low bq, low freq, many artifacts, many samples",UPN2_016,17,7579848,A,T,missense_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu22Gln/c.65T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3908,40,3971,"0,0100730295",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,08",Deleterious,0,Damaging,"29,78","16,1"
"low bq, low freq, many artifacts, many samples",UPN2_017,17,7579848,A,T,missense_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu22Gln/c.65T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2026,30,2065,"0,014527845",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,08",Deleterious,0,Damaging,"29,33","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_018,17,7579848,A,T,missense_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu22Gln/c.65T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3839,41,3903,"0,0105047399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,08",Deleterious,0,Damaging,"29,62","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_002,17,7579848,A,T,missense_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu22Gln/c.65T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),4590,55,4692,"0,0117220801",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,08",Deleterious,0,Damaging,"29,9","16,85"
"low bq, low freq, many artifacts, many samples",UPN2_042,17,7579848,A,T,missense_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu22Gln/c.65T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),7920,99,8094,"0,0122312824",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,08",Deleterious,0,Damaging,"30,17","16,86"
"low bq, low freq, many artifacts, many samples",UPN2_043,17,7579848,A,T,missense_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu22Gln/c.65T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),4573,53,4669,"0,0113514671",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,08",Deleterious,0,Damaging,"30,21",15
"low bq, many samples",UPN2_044,17,7579848,A,T,missense_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu22Gln/c.65T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1850,44,1914,"0,0229885057",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,08",Deleterious,0,Damaging,"29,36","17,8"
"low bq, low freq, many artifacts, many samples",UPN2_031,17,7579848,A,T,missense_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu22Gln/c.65T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3978,42,4039,"0,0103986135",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,08",Deleterious,0,Damaging,"29,58","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_005,17,7579848,A,T,missense_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu22Gln/c.65T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1713,21,1746,"0,0120274914",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,08",Deleterious,0,Damaging,"30,47",14
"low bq, low freq, many artifacts, many samples",UPN2_045,17,7579848,A,T,missense_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu22Gln/c.65T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3424,61,3531,"0,0172755593",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,08",Deleterious,0,Damaging,"28,94","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_046,17,7579848,A,T,missense_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu22Gln/c.65T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),9109,125,9306,"0,0134321943",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,08",Deleterious,0,Damaging,"30,02","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_033,17,7579848,A,T,missense_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu22Gln/c.65T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),4826,54,4916,"0,0109845403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,08",Deleterious,0,Damaging,"29,77","16,54"
"low bq, low freq, many artifacts, many samples",UPN2_034,17,7579848,A,T,missense_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu22Gln/c.65T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1678,24,1712,"0,0140186916",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,08",Deleterious,0,Damaging,"29,49","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_047,17,7579848,A,T,missense_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu22Gln/c.65T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),8322,97,8479,"0,0114400283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,08",Deleterious,0,Damaging,"30,13","16,32"
"low bq, low freq, many artifacts, many samples",UPN2_048,17,7579848,A,T,missense_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu22Gln/c.65T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3325,53,3415,"0,0155197657",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,08",Deleterious,0,Damaging,"30,43","16,87"
"low bq, low freq, many artifacts, many samples",UPN2_006,17,7579848,A,T,missense_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu22Gln/c.65T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3761,39,3830,"0,0101827676",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,08",Deleterious,0,Damaging,"30,7","17,59"
"low bq, low freq, many artifacts, many samples",UPN2_049,17,7579848,A,T,missense_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu22Gln/c.65T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6393,113,6599,"0,0171238066",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,08",Deleterious,0,Damaging,"29,09","17,61"
"low bq, low freq, many artifacts, many samples",UPN2_050,17,7579848,A,T,missense_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu22Gln/c.65T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6132,89,6272,"0,014190051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,08",Deleterious,0,Damaging,"29,9","17,72"
"low bq, low freq, many artifacts, many samples",UPN2_051,17,7579848,A,T,missense_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu22Gln/c.65T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),7013,107,7170,"0,0149232915",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,08",Deleterious,0,Damaging,"29,8","17,44"
"low bq, low freq, many artifacts, many samples",UPN2_052,17,7579848,A,T,missense_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu22Gln/c.65T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3964,50,4043,"0,0123670542",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,08",Deleterious,0,Damaging,"29,99","17,36"
"low bq, low freq, many artifacts, many samples",UPN2_053,17,7579848,A,T,missense_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu22Gln/c.65T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),9132,137,9383,"0,0146008739",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,08",Deleterious,0,Damaging,"29,58","16,57"
"low bq, low freq, many artifacts, many samples",UPN2_054,17,7579848,A,T,missense_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu22Gln/c.65T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6589,76,6709,"0,0113280668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,08",Deleterious,0,Damaging,"29,97","15,68"
"low bq, low freq, many artifacts, many samples",UPN2_007,17,7579848,A,T,missense_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu22Gln/c.65T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),13302,165,13532,"0,0121933195",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,08",Deleterious,0,Damaging,"30,71","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_008,17,7579848,A,T,missense_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu22Gln/c.65T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),18324,192,18622,"0,0103103856",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,08",Deleterious,0,Damaging,"30,55","15,58"
"low bq, low freq, many artifacts, many samples",UPN2_009,17,7579848,A,T,missense_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu22Gln/c.65T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),14204,151,14436,"0,0104599612",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,08",Deleterious,0,Damaging,"30,59","15,77"
"low bq, low freq, many artifacts, many samples",UPN2_010,17,7579848,A,T,missense_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu22Gln/c.65T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),11199,117,11396,"0,0102667603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,08",Deleterious,0,Damaging,"30,55","16,53"
"low bq, low freq, many artifacts, many samples",UPN2_011,17,7579848,A,T,missense_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu22Gln/c.65T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),9953,116,10121,"0,0114613181",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,08",Deleterious,0,Damaging,"30,73","16,71"
"low bq, low freq, many artifacts, many samples",UPN2_055,17,7579848,A,T,missense_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu22Gln/c.65T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),7764,113,7944,"0,014224572",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,08",Deleterious,0,Damaging,"30,15","16,73"
"low bq, low freq, many artifacts, many samples",UPN2_056,17,7579848,A,T,missense_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu22Gln/c.65T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3903,71,3999,"0,0177544386",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,08",Deleterious,0,Damaging,"30,24","20,79"
"low bq, low freq, many artifacts, many samples",UPN2_057,17,7579848,A,T,missense_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu22Gln/c.65T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6869,101,7040,"0,0143465909",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,08",Deleterious,0,Damaging,"29,55","16,01"
"low bq, low freq, many artifacts, many samples",UPN2_058,17,7579848,A,T,missense_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu22Gln/c.65T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),14781,169,15043,"0,0112344612",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,08",Deleterious,0,Damaging,"30,21","15,9"
"low bq, low freq, many artifacts, many samples",UPN2_012,17,7579848,A,T,missense_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu22Gln/c.65T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6148,66,6262,"0,0105397637",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,08",Deleterious,0,Damaging,"30,8","17,06"
"low bq, low freq, many artifacts, many samples",UPN2_013,17,7579848,A,T,missense_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu22Gln/c.65T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3674,39,3732,"0,0104501608",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,08",Deleterious,0,Damaging,"30,65","15,54"
"low bq, low freq, many artifacts, many samples",UPN2_071,17,7579848,A,T,missense_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu22Gln/c.65T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2626,27,2674,"0,0100972326",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,08",Deleterious,0,Damaging,"28,28",14
"low bq, low freq, many artifacts",UPN2_073,17,7579848,A,T,missense_variant(MODERATE|MISSENSE|cTa/cAa|p.Leu22Gln/c.65T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2142,22,2184,"0,0100732601",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,08",Deleterious,0,Damaging,"29,21","18,59"
"low freq, many artifacts",UPN2_052,17,7579849,G,T,missense_variant(MODERATE|MISSENSE|Cta/Ata|p.Leu22Ile/c.64C>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3973,55,4043,"0,0136037596",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,0,Damaging,"32,51","29,38"
"low bq, bad alignment, low freq, many artifacts",UPN2_044,17,7579851,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp21Gly/c.62A>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),1852,33,1917,"0,0172143975",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,13",Deleterious,132,Tolerated,"26,7","23,94"
"low bq, low freq, many artifacts, many samples",UPN2_002,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),4620,50,4693,"0,0106541658",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"27,07","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_089,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),3601,57,3670,"0,0155313351",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"28,65","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_042,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),7932,103,8098,"0,0127191899",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"27,78","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_043,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),4564,69,4671,"0,0147719974",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"27,82","15,3"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),3437,65,3532,"0,018403171",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"26,74","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_046,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),9110,138,9311,"0,0148211793",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"27,6","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_047,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),8317,99,8479,"0,0116759052",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"27,69","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_048,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),3347,41,3414,"0,0120093732",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"27,77",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),6435,109,6602,"0,0165101484",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"26,85","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_050,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),6155,80,6275,"0,012749004",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"27,29","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_051,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),7053,99,7180,"0,0137883008",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"27,51","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_052,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),3967,49,4045,"0,0121137206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"27,79","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_053,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),9199,132,9389,"0,0140590052",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"27,04","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_054,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),6562,86,6711,"0,0128147817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"27,56","15,51"
"low bq, low freq, many artifacts, many samples",UPN2_007,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),13298,150,13536,"0,0110815603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"28,16","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_010,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),11195,125,11401,"0,0109639505",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"27,63","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_055,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),7788,99,7948,"0,0124559638",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"27,47","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_056,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),3930,43,3999,"0,0107526882",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"27,68","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_090,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),2703,33,2741,"0,0120394017",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"28,66","15,64"
"low bq, low freq, many artifacts, many samples",UPN2_057,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),6876,118,7046,"0,0167470905",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"27,28","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_058,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),14779,194,15055,"0,0128860844",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"27,85","14,58"
"low bq, bad alignment, many samples",UPN2_059,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1561,48,1615,"0,0297213622",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"26,78","14,27"
"low bq, bad alignment, many samples",UPN2_060,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1814,56,1877,"0,0298348428",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"26,38","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_093,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),3755,42,3820,"0,0109947644",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"28,96",14
"low bq, bad alignment, many samples",UPN2_061,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),2757,106,2874,"0,0368823939",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"26,5","14,12"
"low bq, bad alignment, many samples",UPN2_062,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),4521,184,4722,"0,0389665396",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"26,15","14,87"
"low bq, bad alignment, many samples",UPN2_063,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1584,82,1673,"0,0490137478",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"25,3","14,78"
"low bq, bad alignment, many samples",UPN2_064,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1727,64,1798,"0,0355951057",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"26,09","14,56"
"low bq, bad alignment, many samples",UPN2_065,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),939,35,974,"0,0359342916",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"26,29","15,51"
"low bq, bad alignment, many samples",UPN2_067,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1006,35,1043,"0,033557047",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"26,49","14,94"
"low bq, bad alignment, many samples",UPN2_068,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),895,46,944,"0,0487288136",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"25,77","15,26"
"low bq, bad alignment, many samples",UPN2_069,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1685,70,1763,"0,0397050482",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"25,84","14,57"
"low bq, bad alignment, many samples",UPN2_070,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1480,38,1523,"0,0249507551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"26,27","15,34"
"low bq, bad alignment, many samples",UPN2_071,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),2578,90,2674,"0,033657442",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"25,94","14,81"
"low bq, bad alignment, many samples",UPN2_072,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),3487,110,3626,"0,0303364589",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"26,18","14,98"
"low bq, bad alignment, many samples",UPN2_073,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),2093,83,2184,"0,038003663",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"26,27","14,61"
"low bq, bad alignment, many samples",UPN2_074,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),594,21,620,"0,0338709677",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"26,55","14,62"
"low bq, bad alignment, many samples",UPN2_075,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),4175,112,4305,"0,0260162602",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"26,7","14,96"
"low bq, bad alignment, many samples",UPN2_076,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1846,73,1930,"0,0378238342",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"26,16","14,55"
"low bq, bad alignment, many samples",UPN2_077,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1865,60,1934,"0,0310237849",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"26,23","15,47"
"low bq, bad alignment, many samples",UPN2_078,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),3668,103,3792,"0,0271624473",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"26,21","15,18"
"low bq, bad alignment, many samples",UPN2_079,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1791,54,1861,"0,0290166577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"26,29","14,48"
"low bq, bad alignment, many samples",UPN2_080,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),3725,109,3846,"0,0283411336",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"26,1","14,43"
"low bq, bad alignment, many samples",UPN2_081,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),5296,150,5467,"0,0274373514",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"26,47","14,64"
"low bq, bad alignment, many samples",UPN2_082,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),872,35,918,"0,0381263617",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"26,41","15,77"
"low bq, bad alignment, many samples",UPN2_083,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1680,55,1754,"0,0313568985",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"25,92","14,58"
"low bq, bad alignment, many samples",UPN2_084,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),2669,83,2767,"0,029996386",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"26,22","14,72"
"low bq, bad alignment, many samples",UPN2_085,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),810,21,835,"0,0251497006",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"26,09",14
"low bq, bad alignment, many samples",UPN2_087,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1399,56,1461,"0,038329911",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"25,91","15,11"
"low bq, bad alignment, many samples",UPN2_088,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1390,52,1448,"0,0359116022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"26,24","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_094,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),3850,48,3914,"0,0122636689",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"28,29","14,15"
"low bq, low freq, many artifacts, many samples",UPN2_096,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),3547,41,3604,"0,0113762486",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"28,92","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_098,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),3226,38,3276,"0,0115995116",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"28,86","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_099,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),2084,25,2119,"0,0117980179",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"28,69","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_100,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),3929,44,3991,"0,0110248058",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"28,5","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_101,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),3352,35,3403,"0,0102850426",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"28,11","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_108,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),7242,74,7338,"0,0100844917",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"28,89","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_110,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),4205,48,4267,"0,0112491212",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"28,32",14
"low bq, low freq, many artifacts",UPN2_111,17,7579851,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp21Ala/c.62A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),4005,57,4081,"0,0139671649",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,29",Deleterious,12,Damaging,"28,04","15,25"
"low bq, low freq, many artifacts",UPN2_006,17,7579854,G,T,stop_gained(HIGH|NONSENSE|tCa/tAa|p.Ser20*/c.59C>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3763,60,3832,"0,01565762",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,41","26,23"
"low freq, many artifacts",UPN2_048,17,7579855,A,G,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser20Pro/c.58T>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),3325,64,3415,"0,0187408492",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,"0,124",Tolerated,"33,26","28,17"
"low freq, many artifacts, many samples",UPN2_048,17,7579856,A,G,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3308,55,3416,"0,0161007026",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,0,Neutral,1,Tolerated,"30,5","29,13"
"low freq, many artifacts, many samples",UPN2_052,17,7579856,A,G,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3948,46,4047,"0,0113664443",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,0,Neutral,1,Tolerated,"30,69","32,74"
"low bq, low freq, many artifacts, many samples",UPN2_017,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2034,25,2066,"0,0121006776",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"31,09","18,68"
"low bq, low freq, many artifacts, many samples",UPN2_018,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3844,48,3906,"0,0122887865",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"31,39",17
"low bq, low freq, many artifacts, many samples",UPN2_020,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3324,40,3372,"0,0118623962",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"31,76","16,83"
"low bq, low freq, many artifacts, many samples",UPN2_024,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2608,31,2654,"0,0116804823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"31,69","15,94"
"low bq, low freq, many artifacts, many samples",UPN2_042,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),7961,94,8100,"0,0116049383",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"30,81","16,47"
"low bq, low freq, many artifacts, many samples",UPN2_043,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),4597,56,4673,"0,0119837364",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"30,82","16,55"
"low bq, low freq, many artifacts, many samples",UPN2_044,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1876,33,1916,"0,017223382",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"30,12","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_029,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6055,64,6145,"0,0104149715",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"31,58","16,94"
"low bq, low freq, many artifacts, many samples",UPN2_045,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3460,56,3537,"0,0158326265",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"29,87","15,79"
"low bq, low freq, many artifacts, many samples",UPN2_046,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),9155,106,9311,"0,0113843841",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"30,69","16,28"
"low bq, low freq, many artifacts, many samples",UPN2_047,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),8346,86,8482,"0,0101391181",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"30,49","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_049,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6469,99,6607,"0,0149841078",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"29,99","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_050,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6173,70,6277,"0,0111518241",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"30,65","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_051,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),7058,97,7187,"0,0134965911",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"30,51","16,7"
"low bq, low freq, many artifacts, many samples",UPN2_039,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),18828,198,19090,"0,0103719225",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"31,32","16,77"
"low bq, low freq, many artifacts, many samples",UPN2_053,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),9220,132,9394,"0,0140515222",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"30,42","16,58"
"low bq, low freq, many artifacts, many samples",UPN2_054,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6598,76,6716,"0,0113162597",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"30,69","18,09"
"low bq, low freq, many artifacts, many samples",UPN2_007,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),13346,140,13538,"0,0103412616",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"31,86","16,89"
"low bq, low freq, many artifacts, many samples",UPN2_055,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),7807,88,7949,"0,0110705749",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"30,76","16,44"
"low bq, low freq, many artifacts, many samples",UPN2_056,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3928,41,3998,"0,0102551276",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"30,52","15,61"
"low bq, low freq, many artifacts, many samples",UPN2_057,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6911,96,7050,"0,0136170213",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"30,46","16,35"
"low bq, low freq, many artifacts, many samples",UPN2_058,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),14798,200,15062,"0,0132784491",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"30,79","17,89"
"low bq, low freq, many artifacts, many samples",UPN2_059,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1579,22,1615,"0,013622291",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"29,26",17
"low bq, low freq, many artifacts, many samples",UPN2_060,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1843,22,1876,"0,0117270789",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"28,93","17,14"
"low bq, low freq, many artifacts, many samples",UPN2_061,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2809,45,2869,"0,0156849076",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"28,67","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_062,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),4621,62,4716,"0,0131467345",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"28,19","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_063,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1639,28,1669,"0,0167765129",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"27,45","15,25"
"low bq, low freq, many artifacts, many samples",UPN2_064,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1754,21,1796,"0,0116926503",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"28,41","16,29"
"low bq, many samples",UPN2_069,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1701,43,1763,"0,0243902439",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"28,03","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_070,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1495,24,1522,"0,0157687254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"28,05","15,46"
"low bq, low freq, many artifacts, many samples",UPN2_071,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2610,52,2674,"0,0194465221",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"28,11","15,69"
"low bq, low freq, many artifacts, many samples",UPN2_072,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3550,48,3628,"0,01323043",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"28,18","16,02"
"low bq, low freq, many artifacts, many samples",UPN2_073,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2125,43,2184,"0,0196886447",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"28,9","15,84"
"low bq, low freq, many artifacts, many samples",UPN2_075,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),4202,56,4304,"0,0130111524",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"29,18","15,5"
"low bq, low freq, many artifacts, many samples",UPN2_076,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1893,30,1929,"0,0155520995",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"28,46","16,43"
"low bq, low freq, many artifacts, many samples",UPN2_077,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1882,36,1933,"0,0186239007",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"28,13","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_078,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3706,69,3789,"0,0182106097",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"28,27","17,41"
"low bq, low freq, many artifacts, many samples",UPN2_079,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1812,34,1860,"0,0182795699",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"28,5","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_080,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3759,69,3844,"0,017950052",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"28,24","15,8"
"low bq, low freq, many artifacts, many samples",UPN2_081,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),5354,72,5462,"0,0131819846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"28,93","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_083,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1707,38,1755,"0,0216524217",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"28,05",14
"low bq, low freq, many artifacts, many samples",UPN2_084,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2708,38,2766,"0,0137382502",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"28,36",14
"low bq, low freq, many artifacts",UPN2_087,17,7579856,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe19Leu/c.57T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1431,23,1460,"0,0157534247",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"27,56","16,3"
"low bq, low freq, many artifacts, many samples",UPN2_017,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2030,22,2066,"0,0106485963",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"30,48","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_002,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),4621,54,4695,"0,0115015974",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"30,29","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_026,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),7257,74,7366,"0,010046158",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"31,07","16,38"
"low bq, low freq, many artifacts, many samples",UPN2_042,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),7947,107,8100,"0,0132098765",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"30,35","15,25"
"low bq, low freq, many artifacts, many samples",UPN2_043,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),4567,78,4674,"0,0166880616",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"30,45","20,01"
"low bq, low freq, many artifacts, many samples",UPN2_044,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1882,29,1917,"0,0151278039",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"29,56","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_029,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6032,87,6145,"0,0141578519",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"31,14","22,08"
"low bq, low freq, many artifacts, many samples",UPN2_030,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6705,74,6828,"0,010837727",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"30,69","17,46"
"low bq, low freq, many artifacts, many samples",UPN2_031,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3985,43,4040,"0,0106435644",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"31,1","17,28"
"low bq, low freq, many artifacts, many samples",UPN2_005,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1710,20,1745,"0,0114613181",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"30,61","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_045,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3451,63,3536,"0,0178167421",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"29,11","17,49"
"low bq, low freq, many artifacts, many samples",UPN2_046,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),9154,122,9316,"0,0130957492",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"30,32","16,31"
"low bq, low freq, many artifacts, many samples",UPN2_047,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),8275,133,8483,"0,0156784157",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"30,29","16,4"
"low bq, low freq, many artifacts, many samples",UPN2_048,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3344,56,3417,"0,016388645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"30,55","16,84"
"low bq, low freq, many artifacts, many samples",UPN2_035,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),11601,130,11778,"0,0110375276",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"31,33","18,54"
"low bq, low freq, many artifacts, many samples",UPN2_049,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6464,113,6608,"0,0171004843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"29,44","15,86"
"low bq, low freq, many artifacts, many samples",UPN2_050,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6156,95,6277,"0,0151346184",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"30,08","17,17"
"low bq, low freq, many artifacts, many samples",UPN2_051,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),7049,107,7189,"0,0148838503",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"30,22","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_052,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3972,48,4048,"0,0118577075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"30,24","16,27"
"low bq, low freq, many artifacts, many samples",UPN2_038,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),12353,131,12539,"0,0104474041",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"31,03","15,82"
"low bq, low freq, many artifacts, many samples",UPN2_053,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),9190,142,9398,"0,0151095978",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"29,81","16,91"
"low bq, low freq, many artifacts, many samples",UPN2_054,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6571,102,6716,"0,0151876117",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"30,57","18,05"
"low bq, low freq, many artifacts, many samples",UPN2_007,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),13321,146,13537,"0,0107852552",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"31,15","16,68"
"low bq, low freq, many artifacts, many samples",UPN2_008,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),18352,199,18628,"0,010682843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"30,65","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_009,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),14214,146,14448,"0,0101052049",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"30,77","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_010,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),11210,140,11407,"0,0122731656",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"30,61","19,13"
"low bq, low freq, many artifacts, many samples",UPN2_011,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),9984,102,10127,"0,0100720845",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"30,78","17,28"
"low bq, low freq, many artifacts, many samples",UPN2_055,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),7806,97,7950,"0,0122012579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"30,29","15,71"
"low bq, low freq, many artifacts, many samples",UPN2_056,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3907,55,4001,"0,0137465634",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"30,2","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_057,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6906,105,7052,"0,0148893931",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"29,94","15,34"
"low bq, low freq, many artifacts, many samples",UPN2_058,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),14782,200,15063,"0,0132775675",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"30,47","15,84"
"low bq, low freq, many artifacts, many samples",UPN2_013,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3684,38,3737,"0,0101685844",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"31,26","15,87"
"low bq, low freq, many artifacts, many samples",UPN2_061,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2801,46,2868,"0,0160390516",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"28,41","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_062,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),4613,63,4717,"0,0133559466",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"27,74","15,1"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1625,27,1669,"0,0161773517",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"26,75","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_064,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1743,34,1796,"0,0189309577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"27,62","15,56"
"low bq, many samples",UPN2_067,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1006,24,1041,"0,023054755",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"28,85","16,12"
"low bq, low freq, many artifacts, many samples",UPN2_069,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1711,27,1764,"0,0153061224",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"27,93","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_070,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1480,21,1523,"0,0137885752",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"28,02","17,33"
"low bq, low freq, many artifacts, many samples",UPN2_071,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2624,33,2675,"0,0123364486",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"27,66","15,45"
"low bq, low freq, many artifacts, many samples",UPN2_072,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3558,54,3628,"0,0148842337",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"27,79","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_073,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2134,42,2183,"0,0192395786",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"28,4","16,52"
"low bq, low freq, many artifacts, many samples",UPN2_075,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),4223,66,4303,"0,0153381362",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"28,73",18
"low bq, low freq, many artifacts, many samples",UPN2_076,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1888,23,1928,"0,0119294606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"28,11","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_077,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1888,24,1933,"0,0124159338",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"28,13","19,96"
"low bq, low freq, many artifacts, many samples",UPN2_078,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3707,42,3787,"0,011090573",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"27,94","16,19"
"low bq, low freq, many artifacts, many samples",UPN2_079,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1817,25,1861,"0,0134336378",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"28,16",14
"low bq, low freq, many artifacts, many samples",UPN2_080,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3745,55,3844,"0,0143080125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"27,95","17,02"
"low bq, low freq, many artifacts, many samples",UPN2_081,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),5362,64,5461,"0,0117194653",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"28,53","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_084,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2697,45,2765,"0,0162748644",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"28,06","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_087,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1419,21,1457,"0,0144131778",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"27,69",14
"low bq, low freq, many artifacts",UPN2_088,17,7579857,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe19Tyr/c.56T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1412,24,1448,"0,0165745856",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,0,Damaging,"28,92",14
"low bq, low freq, many artifacts, many samples",UPN2_045,17,7579858,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe19Val/c.55T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),3419,36,3537,"0,010178117",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"28,89","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_059,17,7579858,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe19Val/c.55T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),1569,22,1614,"0,0136307311",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"27,99","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_060,17,7579858,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe19Val/c.55T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),1833,22,1874,"0,0117395945",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"27,65","15,82"
"low bq, low freq, many artifacts, many samples",UPN2_061,17,7579858,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe19Val/c.55T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),2769,48,2867,"0,0167422393",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"27,4","15,75"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,17,7579858,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe19Val/c.55T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),4575,63,4712,"0,0133701188",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"26,97","14,56"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,17,7579858,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe19Val/c.55T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),1597,27,1662,"0,0162454874",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"25,68","14,48"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,17,7579858,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe19Val/c.55T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),1748,22,1793,"0,0122699387",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"26,88","14,91"
"low bq, bad alignment, many samples",UPN2_068,17,7579858,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe19Val/c.55T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),908,21,942,"0,0222929936",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"26,65","15,9"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_069,17,7579858,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe19Val/c.55T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),1700,20,1765,"0,0113314448",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"26,63","14,65"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,17,7579858,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe19Val/c.55T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),2595,35,2676,"0,0130792227",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"26,35","14,2"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,17,7579858,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe19Val/c.55T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),3528,47,3624,"0,0129690949",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"26,52","14,47"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,17,7579858,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe19Val/c.55T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),1868,22,1924,"0,0114345114",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"26,12","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_077,17,7579858,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe19Val/c.55T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),1872,25,1931,"0,0129466598",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"27,04","15,4"
"low bq, low freq, many artifacts, many samples",UPN2_078,17,7579858,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe19Val/c.55T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),3693,39,3786,"0,0103011094",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"27,04","14,67"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,17,7579858,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe19Val/c.55T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),1692,29,1750,"0,0165714286",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"26,37","14,48"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,17,7579858,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe19Val/c.55T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),2685,37,2762,"0,0133960898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"26,92","14,19"
"low bq, low freq, many artifacts",UPN2_087,17,7579858,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe19Val/c.55T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),1399,23,1454,"0,0158184319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"27,02","14,57"
"low freq, many artifacts",UPN2_093,17,7579858,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe19Leu/c.55T>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),3743,42,3816,"0,0110062893",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,01",Deleterious,0,Damaging,"31,14","30,81"
"low bq, low freq, many artifacts, many samples",UPN2_001,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),4234,66,4322,"0,015270708",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"30,53","16,08"
"low bq, low freq, many artifacts, many samples",UPN2_015,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),9147,103,9285,"0,011093161",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"30,69","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_016,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3904,44,3972,"0,0110775428",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"30,5","15,82"
"low bq, low freq, many artifacts, many samples",UPN2_017,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2026,29,2066,"0,0140367861",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"30,35","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_018,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3833,55,3904,"0,0140881148",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"30,25","17,75"
"low bq, low freq, many artifacts, many samples",UPN2_020,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3317,41,3373,"0,0121553513",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"31,07","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_021,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),5139,60,5217,"0,0115008626",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"30,85","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_002,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),4594,70,4694,"0,0149126545",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"29,49","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_023,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6534,78,6644,"0,0117399157",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"31,38","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_024,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2617,29,2655,"0,0109227872",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"30,89","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_025,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),8490,88,8613,"0,0102171137",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"31,16","15,88"
"low bq, low freq, many artifacts, many samples",UPN2_027,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),8748,115,8931,"0,0128764976",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"30,79","17,3"
"low bq, low freq, many artifacts, many samples",UPN2_089,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3619,38,3671,"0,0103514029",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"30,06","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_042,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),7942,116,8098,"0,0143245246",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"30,2","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_028,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6839,83,6958,"0,0119287151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"31,01","15,17"
"low bq, low freq, many artifacts, many samples",UPN2_043,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),4546,90,4670,"0,0192719486",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"30,33","15,96"
"low bq, many samples",UPN2_044,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1856,45,1916,"0,0234864301",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"28,97","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_030,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6708,88,6827,"0,0128899956",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"30,19","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_031,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3965,52,4039,"0,0128744739",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"30,53","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_032,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3008,42,3065,"0,0137030995",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"31,19","16,4"
"low bq, low freq, many artifacts, many samples",UPN2_046,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),9084,158,9315,"0,0169618894",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,30,"15,8"
"low bq, low freq, many artifacts, many samples",UPN2_033,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),4837,61,4918,"0,012403416",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"30,66","15,74"
"low bq, low freq, many artifacts, many samples",UPN2_034,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1681,24,1712,"0,0140186916",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"30,09","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_047,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),8270,156,8487,"0,0183810534",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"30,05","15,88"
"low bq, low freq, many artifacts, many samples",UPN2_048,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3341,57,3422,"0,0166569258",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"30,06","16,21"
"low bq, low freq, many artifacts, many samples",UPN2_035,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),11588,132,11776,"0,0112092391",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"31,06","15,48"
"low bq, low freq, many artifacts, many samples",UPN2_036,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),21606,320,22028,"0,0145269657",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"30,6","17,55"
"low bq, many samples",UPN2_049,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6383,159,6609,"0,0240581026",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"28,88","16,74"
"low bq, low freq, many artifacts, many samples",UPN2_050,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6095,126,6279,"0,0200668896",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"29,7","15,86"
"low bq, low freq, many artifacts, many samples",UPN2_037,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),10362,106,10508,"0,0100875523",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"30,9","15,9"
"low bq, low freq, many artifacts, many samples",UPN2_051,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),7000,134,7188,"0,0186421814",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"29,67","16,62"
"low bq, low freq, many artifacts, many samples",UPN2_052,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3963,60,4049,"0,0148184737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"30,01","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_038,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),12355,140,12538,"0,0111660552",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"30,74","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_039,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),18768,243,19091,"0,0127285108",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"29,92","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_053,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),9121,206,9398,"0,0219195574",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"29,45","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_054,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6558,116,6717,"0,0172696144",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"29,99","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_007,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),13289,183,13537,"0,0135185048",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"30,53","15,73"
"low bq, low freq, many artifacts, many samples",UPN2_008,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),18230,262,18621,"0,0140701359",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"30,02","15,78"
"low bq, low freq, many artifacts, many samples",UPN2_009,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),14156,213,14447,"0,0147435454",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"30,18","15,42"
"low bq, low freq, many artifacts, many samples",UPN2_010,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),11196,137,11405,"0,0120122753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"29,88","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_011,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),9948,120,10125,"0,0118518519",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"30,11","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_055,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),7774,128,7951,"0,0160986039",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"30,13","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_056,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3892,79,4001,"0,0197450637",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"29,97","16,28"
"low bq, low freq, many artifacts, many samples",UPN2_090,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2701,30,2739,"0,0109529025",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"30,96",14
"low bq, low freq, many artifacts, many samples",UPN2_057,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6848,140,7053,"0,0198497093",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"29,44","15,63"
"low bq, low freq, many artifacts, many samples",UPN2_058,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),14708,266,15059,"0,0176638555",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"30,27","15,66"
"low bq, low freq, many artifacts, many samples",UPN2_040,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),7973,116,8134,"0,0142611261",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"30,09","15,55"
"low bq, low freq, many artifacts, many samples",UPN2_013,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3675,48,3740,"0,0128342246",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"30,54",14
"low bq, low freq, many artifacts, many samples",UPN2_091,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3754,42,3827,"0,0109746538",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"30,78","18,05"
"low bq, low freq, many artifacts, many samples",UPN2_073,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2148,22,2183,"0,0100778745",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"27,43",14
"low bq, low freq, many artifacts, many samples",UPN2_075,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),4210,55,4302,"0,0127847513",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"27,69","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_079,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1811,23,1858,"0,012378902",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"27,17",14
"low bq, low freq, many artifacts, many samples",UPN2_080,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3753,42,3839,"0,010940349",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"27,28","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_081,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),5332,73,5461,"0,0133675151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"27,57","15,53"
"low bq, bad alignment, many samples",UPN2_086,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),736,23,780,"0,0294871795",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"26,73","17,43"
"low bq, low freq, many artifacts, many samples",UPN2_095,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),4344,47,4405,"0,0106696935",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"30,76","17,28"
"low bq, low freq, many artifacts, many samples",UPN2_099,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2087,22,2118,"0,0103871577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"30,98","15,64"
"low bq, low freq, many artifacts, many samples",UPN2_100,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3927,42,3993,"0,0105184072",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"30,26","15,48"
"low bq, low freq, many artifacts, many samples",UPN2_107,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),5221,59,5303,"0,0111257779",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"30,23","14,75"
"low bq, low freq, many artifacts",UPN2_111,17,7579858,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe19Ile/c.55T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),4024,44,4083,"0,0107763899",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,95",Deleterious,0,Damaging,"30,03","16,7"
"low bq, low freq, many artifacts, many samples",UPN2_061,17,7579861,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr18Pro/c.52A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),2814,33,2870,"0,0114982578",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,87",Deleterious,1,Damaging,"28,98","16,48"
"low bq, low freq, many artifacts, many samples",UPN2_063,17,7579861,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr18Pro/c.52A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1626,29,1663,"0,0174383644",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,87",Deleterious,1,Damaging,"28,2","15,97"
"low bq, low freq, many artifacts, many samples",UPN2_064,17,7579861,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr18Pro/c.52A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1752,27,1793,"0,0150585611",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,87",Deleterious,1,Damaging,"28,9","18,89"
"low bq, low freq, many artifacts, many samples",UPN2_069,17,7579861,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr18Pro/c.52A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1738,20,1764,"0,0113378685",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,87",Deleterious,1,Damaging,"28,57",14
"low bq, low freq, many artifacts, many samples",UPN2_071,17,7579861,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr18Pro/c.52A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),2626,29,2678,"0,0108289768",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,87",Deleterious,1,Damaging,"28,46","16,59"
"low bq, low freq, many artifacts, many samples",UPN2_072,17,7579861,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr18Pro/c.52A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),3548,40,3622,"0,0110436223",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,87",Deleterious,1,Damaging,"28,64","16,6"
"low bq, low freq, many artifacts, many samples",UPN2_075,17,7579861,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr18Pro/c.52A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),4229,49,4298,"0,0114006515",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,87",Deleterious,1,Damaging,"29,36","19,96"
"low bq, low freq, many artifacts, many samples",UPN2_076,17,7579861,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr18Pro/c.52A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1868,30,1921,"0,0156168662",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,87",Deleterious,1,Damaging,"28,76","17,33"
"low bq, low freq, many artifacts, many samples",UPN2_077,17,7579861,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr18Pro/c.52A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1887,28,1927,"0,0145303581",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,87",Deleterious,1,Damaging,"28,65","17,57"
"low bq, low freq, many artifacts, many samples",UPN2_079,17,7579861,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr18Pro/c.52A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1827,24,1858,"0,0129171152",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,87",Deleterious,1,Damaging,"28,97","15,58"
"low bq, low freq, many artifacts, many samples",UPN2_080,17,7579861,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr18Pro/c.52A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),3760,47,3835,"0,0122555411",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,87",Deleterious,1,Damaging,"29,01","15,98"
"low bq, low freq, many artifacts, many samples",UPN2_081,17,7579861,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr18Pro/c.52A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),5354,64,5457,"0,0117280557",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,87",Deleterious,1,Damaging,"29,13","19,91"
"low bq, low freq, many artifacts, many samples",UPN2_083,17,7579861,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr18Pro/c.52A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1702,25,1749,"0,0142938822",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,87",Deleterious,1,Damaging,"28,38","15,76"
"low bq, low freq, many artifacts, many samples",UPN2_084,17,7579861,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr18Pro/c.52A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),2705,32,2759,"0,0115984052",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,87",Deleterious,1,Damaging,"28,97","16,47"
"low bq, low freq, many artifacts",UPN2_087,17,7579861,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr18Pro/c.52A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1410,24,1450,"0,0165517241",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,87",Deleterious,1,Damaging,"28,84","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_062,17,7579863,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu17Ala/c.50A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),2417,28,2460,"0,0113821138",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,02",Neutral,"0,01",Damaging,"28,01","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_072,17,7579863,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu17Ala/c.50A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1861,22,1893,"0,0116217644",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,02",Neutral,"0,01",Damaging,"27,6","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_089,17,7579865,C,G,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln16His/c.48G>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1802,22,1825,"0,0120547945",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,1,Damaging,"32,13","15,18"
"low bq, low freq, many artifacts",UPN2_051,17,7579865,C,G,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln16His/c.48G>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),3512,36,3564,"0,0101010101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,1,Damaging,"31,56",14
"low bq, low freq, many artifacts, many samples",UPN2_045,17,7579868,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser15Arg/c.45T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),1694,30,1746,"0,0171821306",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,0,Damaging,"28,88","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_049,17,7579868,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser15Arg/c.45T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),3185,45,3272,"0,0137530562",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,0,Damaging,"28,55",14
"low bq, low freq, many artifacts, many samples",UPN2_062,17,7579868,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser15Arg/c.45T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),2296,27,2347,"0,0115040477",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,0,Damaging,"29,78","15,3"
"low bq, low freq, many artifacts, many samples",UPN2_002,17,7579868,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser15Arg/c.45T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2276,26,2329,"0,0111635895",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,0,Damaging,"29,27","15,54"
"low bq, low freq, many artifacts, many samples",UPN2_043,17,7579868,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser15Arg/c.45T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2283,25,2326,"0,0107480653",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,0,Damaging,"30,81","18,08"
"low bq, low freq, many artifacts, many samples",UPN2_047,17,7579868,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser15Arg/c.45T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),4136,47,4221,"0,0111348022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,0,Damaging,"30,51","17,38"
"low bq, low freq, many artifacts, many samples",UPN2_050,17,7579868,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser15Arg/c.45T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3032,38,3101,"0,0122541116",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,0,Damaging,"29,72","18,63"
"low bq, low freq, many artifacts, many samples",UPN2_053,17,7579868,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser15Arg/c.45T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),4545,54,4655,"0,0116004296",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,0,Damaging,"29,48","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_058,17,7579868,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser15Arg/c.45T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),7306,82,7456,"0,0109978541",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,0,Damaging,"30,7","18,3"
"low bq, low freq, many artifacts",UPN2_012,17,7579868,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser15Arg/c.45T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3040,34,3110,"0,0109324759",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,0,Damaging,"30,7","18,79"
"low bq, low freq, many artifacts",UPN2_081,17,7579869,C,G,missense_variant(MODERATE|MISSENSE|aGt/aCt|p.Ser15Thr/c.44G>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),2667,32,2714,"0,0117907148",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,"0,02",Damaging,"30,94","14,97"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_016,17,7579872,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu14Arg/c.41T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),1895,24,1977,"0,0121396055",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,0,Damaging,"26,89",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_018,17,7579872,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu14Arg/c.41T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),1865,21,1939,"0,0108303249",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,0,Damaging,"26,38",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_002,17,7579872,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu14Arg/c.41T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),2204,43,2329,"0,0184628596",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,0,Damaging,"24,84","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_042,17,7579872,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu14Arg/c.41T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),3851,41,4021,"0,0101964685",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,0,Damaging,"27,49","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_043,17,7579872,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu14Arg/c.41T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),2217,29,2326,"0,0124677558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,0,Damaging,"27,62","14,76"
"low bq, bad alignment, many samples",UPN2_044,17,7579872,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu14Arg/c.41T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),891,25,950,"0,0263157895",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,0,Damaging,"25,18","14,52"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_030,17,7579872,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu14Arg/c.41T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),3256,34,3386,"0,0100413467",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,0,Damaging,"26,47","16,35"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_031,17,7579872,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu14Arg/c.41T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),1925,25,2003,"0,0124812781",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,0,Damaging,"26,25","15,04"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,17,7579872,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu14Arg/c.41T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),1633,36,1748,"0,0205949657",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,0,Damaging,"24,62","14,19"
"low bq, low freq, many artifacts, many samples",UPN2_046,17,7579872,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu14Arg/c.41T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),4406,50,4627,"0,0108061379",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,0,Damaging,"27,43","14,86"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_033,17,7579872,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu14Arg/c.41T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),2363,25,2446,"0,0102207686",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,0,Damaging,"26,57","15,16"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_036,17,7579872,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu14Arg/c.41T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),10506,124,10951,"0,0113231668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,0,Damaging,"26,15","14,74"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_006,17,7579872,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu14Arg/c.41T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),1838,24,1907,"0,0125852124",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,0,Damaging,"26,24","14,92"
"low bq, bad alignment, many samples",UPN2_049,17,7579872,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu14Arg/c.41T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),3045,80,3276,"0,0244200244",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,0,Damaging,"24,87","14,36"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,17,7579872,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu14Arg/c.41T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),2954,50,3101,"0,016123831",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,0,Damaging,"26,31","15,64"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,17,7579872,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu14Arg/c.41T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),3379,55,3561,"0,0154450997",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,0,Damaging,"26,74","14,13"
"low bq, low freq, many artifacts, many samples",UPN2_052,17,7579872,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu14Arg/c.41T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),1920,26,2009,"0,0129417621",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,0,Damaging,"27,89","15,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,17,7579872,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu14Arg/c.41T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),4406,76,4658,"0,0163160155",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,0,Damaging,"26,42","14,58"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_007,17,7579872,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu14Arg/c.41T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),6436,80,6726,"0,0118941421",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,0,Damaging,"26,13","14,77"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_008,17,7579872,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu14Arg/c.41T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),8889,100,9263,"0,0107956386",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,0,Damaging,"26,08","15,38"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_009,17,7579872,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu14Arg/c.41T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),6860,86,7176,"0,0119843924",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,0,Damaging,"26,02","14,51"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_010,17,7579872,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu14Arg/c.41T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),5425,75,5662,"0,0132462028",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,0,Damaging,26,"15,33"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_011,17,7579872,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu14Arg/c.41T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),4813,57,5012,"0,0113727055",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,0,Damaging,"26,55","16,09"
"low bq, low freq, many artifacts, many samples",UPN2_056,17,7579872,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu14Arg/c.41T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),1885,29,1991,"0,014565545",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,0,Damaging,"27,7","15,07"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,17,7579872,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu14Arg/c.41T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),3298,57,3490,"0,0163323782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,0,Damaging,"25,9","15,58"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_012,17,7579872,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu14Arg/c.41T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),2980,45,3110,"0,0144694534",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,0,Damaging,"26,3",14
"low bq, many samples",UPN2_060,17,7579872,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu14Arg/c.41T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),891,21,931,"0,022556391",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,0,Damaging,"28,03","20,95"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_040,17,7579872,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu14Arg/c.41T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),3887,48,4030,"0,01191067",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,0,Damaging,"26,14","16,25"
"low bq, low freq, many artifacts, many samples",UPN2_062,17,7579872,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu14Arg/c.41T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),2267,31,2347,"0,0132083511",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,0,Damaging,"28,14","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_072,17,7579872,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu14Arg/c.41T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),1735,30,1801,"0,0166574125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,0,Damaging,"27,56","14,6"
"low bq, low freq, many artifacts",UPN2_080,17,7579872,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu14Arg/c.41T>G|393|TP53|protein_coding|CODING|ENST00000269305|2|C),1858,23,1913,"0,0120230005",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,0,Damaging,"28,68","14,57"
"low bq, bad alignment, many samples",UPN2_001,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2065,59,2147,"0,0274802049",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"26,34","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_014,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3113,59,3203,"0,018420231",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"27,9","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_015,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),4465,101,4607,"0,0219231604",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"27,49","15,49"
"low bq, bad alignment, many samples",UPN2_017,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),986,35,1028,"0,0340466926",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"26,24","16,89"
"low bq, low freq, many artifacts, many samples",UPN2_019,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2743,48,2817,"0,0170394036",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"27,36","16,44"
"low bq, many samples",UPN2_020,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1614,44,1675,"0,0262686567",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"28,12","16,41"
"low bq, low freq, many artifacts, many samples",UPN2_021,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2523,46,2598,"0,0177059276",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"27,84","16,48"
"low bq, low freq, many artifacts, many samples",UPN2_022,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3371,52,3463,"0,0150158822",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"27,98","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_023,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3205,65,3309,"0,0196433968",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"27,74","16,31"
"low bq, low freq, many artifacts, many samples",UPN2_024,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1280,29,1319,"0,0219863533",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"28,01","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_025,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),4156,89,4284,"0,0207749767",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"27,94","15,91"
"low bq, low freq, many artifacts, many samples",UPN2_026,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3570,61,3669,"0,0166257836",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"27,76","16,31"
"low bq, many samples",UPN2_027,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),4288,120,4441,"0,0270209412",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"27,55","15,88"
"low bq, low freq, many artifacts, many samples",UPN2_089,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1786,26,1827,"0,0142309797",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"28,37","16,54"
"low bq, low freq, many artifacts, many samples",UPN2_028,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3367,62,3464,"0,0178983834",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"27,24","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_029,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2989,47,3057,"0,0153745502",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"27,79","17,72"
"low bq, low freq, many artifacts, many samples",UPN2_032,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1470,33,1518,"0,0217391304",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"27,78","18,09"
"low bq, many samples",UPN2_047,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),4049,110,4219,"0,026072529",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"27,35","16,18"
"low bq, many samples",UPN2_048,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1648,41,1708,"0,0240046838",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"27,69","17,63"
"low bq, many samples",UPN2_035,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),5668,138,5856,"0,0235655738",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"27,58","16,41"
"low bq, low freq, many artifacts, many samples",UPN2_037,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),5088,100,5233,"0,0191094974",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"27,7","15,45"
"low bq, many samples",UPN2_038,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6038,138,6241,"0,0221118411",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"27,71","16,35"
"low bq, bad alignment, many samples",UPN2_039,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),9167,212,9504,"0,0223063973",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"25,87","15,64"
"low bq, many samples",UPN2_054,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3197,90,3335,"0,0269865067",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"27,43","16,54"
"low bq, many samples",UPN2_055,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3781,113,3942,"0,028665652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"27,76","16,61"
"low bq, low freq, many artifacts, many samples",UPN2_090,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1353,20,1381,"0,0144822592",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"29,41",16
"low bq, many samples",UPN2_058,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),7145,230,7458,"0,0308393671",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"27,45","15,77"
"low bq, bad alignment, many samples",UPN2_013,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1777,44,1852,"0,0237580994",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"26,28","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_093,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1863,20,1904,"0,0105042017",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"29,87","17,95"
"low bq, low freq, many artifacts, many samples",UPN2_071,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1282,25,1328,"0,0188253012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"27,46","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_075,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2077,33,2134,"0,0154639175",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"28,67","17,67"
"low bq, low freq, many artifacts, many samples",UPN2_078,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1819,33,1880,"0,0175531915",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"28,31","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_081,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2652,37,2715,"0,0136279926",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"28,4","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_084,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1336,22,1374,"0,0160116448",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"28,66",14
"low bq, low freq, many artifacts, many samples",UPN2_094,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1904,29,1949,"0,0148794253",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"28,49","16,14"
"low bq, low freq, many artifacts, many samples",UPN2_095,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2158,24,2196,"0,0109289617",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"29,36","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_096,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1748,29,1791,"0,0161920715",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"30,13","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_097,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2005,25,2045,"0,0122249389",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"29,55",15
"low bq, low freq, many artifacts, many samples",UPN2_098,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1597,24,1636,"0,0146699267",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"29,87","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_100,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1943,27,1989,"0,0135746606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"28,28","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_101,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1641,25,1687,"0,0148192057",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"28,62","15,76"
"low bq, low freq, many artifacts, many samples",UPN2_102,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1793,27,1831,"0,0147460404",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"29,46","18,07"
"low bq, low freq, many artifacts, many samples",UPN2_103,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2303,38,2358,"0,016115352",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"29,57","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_104,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2084,28,2133,"0,0131270511",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"29,82","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_106,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1948,31,1998,"0,0155155155",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"28,62","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_107,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2576,38,2641,"0,0143884892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"28,44","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_108,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3577,41,3647,"0,0112421168",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"29,4","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_109,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2737,32,2781,"0,0115066523",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"29,71","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_110,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2090,31,2134,"0,0145267104",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"28,59","16,71"
"low bq, low freq, many artifacts",UPN2_111,17,7579872,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu14Gln/c.41T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1981,31,2035,"0,0152334152",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,0,Damaging,"28,25",15
"low bq, low freq, many artifacts, many samples",UPN2_001,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),2124,27,2152,"0,0125464684",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"27,18",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_002,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),2294,32,2330,"0,0137339056",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"26,33","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_089,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1804,23,1830,"0,012568306",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"27,8","15,83"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),3936,65,4030,"0,0161290323",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"26,67","14,2"
"low bq, low freq, many artifacts, many samples",UPN2_043,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),2286,35,2333,"0,0150021432",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"27,01",15
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_044,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),919,20,952,"0,0210084034",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"25,44","15,75"
"low bq, bad alignment, many samples",UPN2_045,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1704,45,1755,"0,0256410256",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"24,99",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),4540,73,4635,"0,0157497303",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"26,37","14,78"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),4128,83,4231,"0,0196171118",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"26,66","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_048,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1674,32,1712,"0,0186915888",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"27,08","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_006,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1888,21,1914,"0,0109717868",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"27,63",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),3203,57,3292,"0,0173147023",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"25,18","14,67"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),3048,56,3117,"0,0179659929",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"25,53","14,23"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),3501,58,3576,"0,0162192394",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"26,2","14,12"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1975,28,2013,"0,0139095877",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"26,5","14,79"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),4588,72,4682,"0,0153780436",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"25,65","14,18"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),3296,38,3343,"0,0113670356",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"26,14",14
"low bq, low freq, many artifacts, many samples",UPN2_007,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),6602,100,6736,"0,0148456057",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"27,36","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_008,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),9144,117,9285,"0,0126009693",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"27,2","14,53"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_009,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),7061,102,7184,"0,0141982183",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"26,95","15,08"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_010,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),5561,84,5668,"0,0148200423",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"26,97","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_011,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),4957,51,5020,"0,0101593625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"27,13","15,04"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),3875,60,3953,"0,0151783456",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"26,52",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1963,31,1997,"0,0155232849",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"26,41","14,23"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),3425,56,3505,"0,0159771755",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"25,94",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_058,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),7351,108,7487,"0,0144250033",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"26,76",15
"low bq, bad alignment, many samples",UPN2_059,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),774,28,804,"0,0348258706",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"25,2",15
"low bq, low freq, many artifacts, many samples",UPN2_012,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),3057,40,3116,"0,0128369705",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"27,47","14,5"
"low bq, bad alignment, many samples",UPN2_060,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),888,39,933,"0,0418006431",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"24,91","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_013,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1823,27,1855,"0,0145552561",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"27,39","15,07"
"low bq, bad alignment, many samples",UPN2_061,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1379,53,1433,"0,0369853454",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"25,15","14,89"
"low bq, bad alignment, many samples",UPN2_062,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),2251,93,2353,"0,0395240119",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"24,92","14,69"
"low bq, bad alignment, many samples",UPN2_063,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),781,47,832,"0,0564903846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"25,16","14,3"
"low bq, bad alignment, many samples",UPN2_064,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),864,30,896,"0,0334821429",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"25,94",14
"low bq, bad alignment, many samples",UPN2_069,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),841,31,877,"0,0353477765",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"25,43","15,26"
"low bq, bad alignment, many samples",UPN2_070,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),721,32,756,"0,0423280423",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"24,94","14,41"
"low bq, bad alignment, many samples",UPN2_071,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1274,55,1330,"0,0413533835",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"25,47","14,24"
"low bq, bad alignment, many samples",UPN2_072,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1734,64,1806,"0,0354374308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"25,51","14,31"
"low bq, bad alignment, many samples",UPN2_073,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1051,34,1089,"0,0312213039",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"26,12","15,12"
"low bq, bad alignment, many samples",UPN2_075,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),2058,77,2143,"0,0359309379",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"25,46","14,64"
"low bq, bad alignment, many samples",UPN2_076,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),925,39,964,"0,0404564315",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"24,72","14,69"
"low bq, bad alignment, many samples",UPN2_077,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),934,28,964,"0,0290456432",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"24,82","15,68"
"low bq, bad alignment, many samples",UPN2_078,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1826,52,1883,"0,0276155072",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"25,44","14,13"
"low bq, bad alignment, many samples",UPN2_079,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),888,35,926,"0,0377969762",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"25,56","14,4"
"low bq, bad alignment, many samples",UPN2_080,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1836,76,1917,"0,0396452791",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"25,39","15,33"
"low bq, bad alignment, many samples",UPN2_081,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),2616,91,2716,"0,0335051546",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"25,41","14,59"
"low bq, bad alignment, many samples",UPN2_083,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),836,30,867,"0,0346020761",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"25,14","15,03"
"low bq, bad alignment, many samples",UPN2_084,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1321,53,1381,"0,038377987",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"25,43","14,13"
"low bq, bad alignment, many samples",UPN2_087,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),687,30,722,"0,0415512465",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"24,86","16,3"
"low bq, bad alignment, many samples",UPN2_088,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),689,24,714,"0,0336134454",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,26,14
"low bq, low freq, many artifacts, many samples",UPN2_094,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1918,28,1952,"0,0143442623",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"27,63",14
"low bq, low freq, many artifacts, many samples",UPN2_097,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),2014,25,2047,"0,0122129946",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"27,68",14
"low bq, low freq, many artifacts, many samples",UPN2_098,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1606,26,1637,"0,0158827123",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"27,58","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_100,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1965,23,1996,"0,0115230461",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"27,83","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_101,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1666,26,1693,"0,0153573538",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"27,17","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_105,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1899,21,1928,"0,0108921162",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"27,59",14
"low bq, low freq, many artifacts, many samples",UPN2_106,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1971,25,2000,"0,0125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"27,49","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_107,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),2600,34,2645,"0,0128544423",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"27,58","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_109,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),2749,29,2785,"0,0104129264",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"27,61","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_110,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),2099,30,2135,"0,0140515222",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"27,26","14,47"
"low bq, low freq, many artifacts",UPN2_111,17,7579881,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu11Ala/c.32A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),2000,30,2040,"0,0147058824",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,5,Damaging,"27,3","15,93"
"low bq, low freq, many artifacts, many samples",UPN2_051,17,7579884,A,T,missense_variant(MODERATE|MISSENSE|gTc/gAc|p.Val10Asp/c.29T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3532,37,3580,"0,0103351955",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,2,Damaging,"33,58","16,81"
"low bq, low freq, many artifacts, many samples",UPN2_053,17,7579884,A,T,missense_variant(MODERATE|MISSENSE|gTc/gAc|p.Val10Asp/c.29T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),4596,66,4684,"0,0140905209",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,2,Damaging,"33,48","18,62"
"low bq, low freq, many artifacts, many samples",UPN2_057,17,7579884,A,T,missense_variant(MODERATE|MISSENSE|gTc/gAc|p.Val10Asp/c.29T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3445,39,3505,"0,0111269615",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,2,Damaging,"33,38","16,92"
"low bq, low freq, many artifacts",UPN2_058,17,7579884,A,T,missense_variant(MODERATE|MISSENSE|gTc/gAc|p.Val10Asp/c.29T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),7388,76,7489,"0,0101482174",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,2,Damaging,"33,53","18,37"
"low bq, low freq, many artifacts, many samples",UPN2_010,17,7579891,G,T,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro8Thr/c.22C>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),5601,64,5670,"0,011287478",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,639,Tolerated,"32,73","19,42"
"low bq, low freq, many artifacts, many samples",UPN2_080,17,7579891,G,T,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro8Thr/c.22C>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1895,20,1919,"0,0104220948",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,639,Tolerated,"32,73","16,2"
"low bq, low freq, many artifacts, many samples",UPN2_049,17,7579892,A,T,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp7Glu/c.21T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3245,37,3296,"0,0112257282",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,499,Tolerated,"33,35","20,89"
"low bq, low freq, many artifacts",UPN2_053,17,7579892,A,T,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp7Glu/c.21T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),4614,56,4685,"0,0119530416",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,499,Tolerated,"33,65","17,91"
"low bq, low freq, many artifacts, many samples",UPN2_049,17,7579893,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp7Ala/c.20A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),3254,33,3296,"0,0100121359",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,6,Damaging,"29,08",14
"low bq, low freq, many artifacts, many samples",UPN2_052,17,7579893,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp7Ala/c.20A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1981,22,2012,"0,0109343936",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,6,Damaging,"29,04","17,59"
"low bq, low freq, many artifacts, many samples",UPN2_053,17,7579893,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp7Ala/c.20A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),4615,52,4686,"0,0110968843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,6,Damaging,"28,9","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_056,17,7579893,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp7Ala/c.20A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1966,21,1997,"0,0105157737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,6,Damaging,"29,48","15,38"
"low bq, bad alignment, many samples",UPN2_060,17,7579893,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp7Ala/c.20A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),902,28,933,"0,0300107181",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,6,Damaging,"26,78","14,5"
"low bq, bad alignment, many samples",UPN2_061,17,7579893,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp7Ala/c.20A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1396,38,1435,"0,0264808362",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,6,Damaging,"26,21","14,55"
"low bq, bad alignment, many samples",UPN2_062,17,7579893,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp7Ala/c.20A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),2284,60,2353,"0,0254993625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,6,Damaging,"26,26","14,72"
"low bq, many samples",UPN2_063,17,7579893,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp7Ala/c.20A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),811,23,835,"0,0275449102",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,6,Damaging,"27,04","14,91"
"low bq, many samples",UPN2_064,17,7579893,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp7Ala/c.20A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),870,25,896,"0,0279017857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,6,Damaging,"27,19","14,28"
"low bq, bad alignment, many samples",UPN2_069,17,7579893,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp7Ala/c.20A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),846,25,877,"0,0285062714",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,6,Damaging,"26,61","14,88"
"low bq, bad alignment, many samples",UPN2_071,17,7579893,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp7Ala/c.20A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1283,46,1331,"0,0345604808",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,6,Damaging,"26,34","14,54"
"low bq, bad alignment, many samples",UPN2_072,17,7579893,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp7Ala/c.20A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1753,49,1808,"0,0271017699",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,6,Damaging,"26,53","14,14"
"low bq, bad alignment, many samples",UPN2_075,17,7579893,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp7Ala/c.20A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),2082,55,2144,"0,0256529851",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,6,Damaging,"26,77","14,49"
"low bq, bad alignment, many samples",UPN2_076,17,7579893,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp7Ala/c.20A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),925,32,965,"0,0331606218",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,6,Damaging,"26,32","14,66"
"low bq, bad alignment, many samples",UPN2_077,17,7579893,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp7Ala/c.20A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),932,30,964,"0,031120332",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,6,Damaging,"26,67","14,9"
"low bq, bad alignment, many samples",UPN2_078,17,7579893,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp7Ala/c.20A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1829,50,1884,"0,0265392781",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,6,Damaging,"26,74","14,72"
"low bq, bad alignment, many samples",UPN2_079,17,7579893,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp7Ala/c.20A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),903,21,927,"0,0226537217",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,6,Damaging,"26,49","14,33"
"low bq, bad alignment, many samples",UPN2_080,17,7579893,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp7Ala/c.20A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1866,52,1919,"0,0270974466",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,6,Damaging,"26,37","14,52"
"low bq, bad alignment, many samples",UPN2_081,17,7579893,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp7Ala/c.20A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),2647,63,2718,"0,0231788079",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,6,Damaging,"26,92","14,51"
"low bq, bad alignment, many samples",UPN2_083,17,7579893,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp7Ala/c.20A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),839,25,869,"0,0287686997",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,6,Damaging,"26,48",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,17,7579893,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp7Ala/c.20A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),1344,29,1381,"0,0209992759",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,6,Damaging,"26,71","14,62"
low bq,UPN2_088,17,7579893,T,G,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp7Ala/c.20A>C|393|TP53|protein_coding|CODING|ENST00000269305|2|G),694,22,716,"0,030726257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,6,Damaging,"27,07","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_046,17,7579897,A,T,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser6Thr/c.16T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),4564,54,4639,"0,0116404397",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,57,Tolerated,"33,31","17,44"
"low bq, low freq, many artifacts, many samples",UPN2_048,17,7579897,A,T,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser6Thr/c.16T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1681,21,1715,"0,012244898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,57,Tolerated,"33,29","20,1"
"low bq, low freq, many artifacts, many samples",UPN2_049,17,7579897,A,T,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser6Thr/c.16T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3243,33,3297,"0,0100090992",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,57,Tolerated,"33,28","18,3"
"low bq, low freq, many artifacts, many samples",UPN2_051,17,7579897,A,T,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser6Thr/c.16T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3535,36,3586,"0,0100390407",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,57,Tolerated,"33,36","15,58"
"low bq, low freq, many artifacts",UPN2_058,17,7579897,A,T,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser6Thr/c.16T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),7379,84,7494,"0,0112089672",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,39",Neutral,57,Tolerated,"33,45","18,19"
"low freq, many artifacts",UPN2_048,17,7579901,CG,C,frameshift_variant(HIGH||ccg/|p.Pro4fs/c.11delC|393|TP53|protein_coding|CODING|ENST00000269305|2|C),1677,30,1716,"0,0174825175",0,0,0,1,1,0,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,59",NA
"low freq, many artifacts",UPN2_061,17,7579910,C,T,start_lost(HIGH|MISSENSE|atG/atA|p.Met1?/c.3G>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1397,25,1435,"0,0174216028",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,82",Neutral,"0,005",Damaging,"33,2","33,92"
"low bq, low freq, many artifacts, many samples",UPN2_001,17,7579911,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2104,34,2146,"0,0158434296",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,0,Damaging,"33,63","22,65"
"low bq, low freq, many artifacts, many samples",UPN2_014,17,7579911,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3161,35,3205,"0,0109204368",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,0,Damaging,"34,14","19,43"
"low bq, low freq, many artifacts, many samples",UPN2_016,17,7579911,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1967,23,2000,"0,0115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,0,Damaging,"34,3","24,35"
"low bq, low freq, many artifacts, many samples",UPN2_018,17,7579911,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1916,21,1946,"0,0107913669",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,0,Damaging,"34,1","20,57"
"low bq, low freq, many artifacts, many samples",UPN2_002,17,7579911,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2298,34,2333,"0,0145735105",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,0,Damaging,"33,55","17,88"
"low bq, low freq, many artifacts, many samples",UPN2_023,17,7579911,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3275,34,3319,"0,0102440494",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,0,Damaging,"34,2","17,88"
"low bq, low freq, many artifacts, many samples",UPN2_026,17,7579911,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3622,43,3673,"0,0117070515",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,0,Damaging,"34,36","21,81"
"low bq, low freq, many artifacts, many samples",UPN2_042,17,7579911,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3951,69,4040,"0,0170792079",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,0,Damaging,"33,56","18,58"
"low bq, low freq, many artifacts, many samples",UPN2_043,17,7579911,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),2292,34,2337,"0,0145485665",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,0,Damaging,"33,47","18,03"
"low bq, low freq, many artifacts, many samples",UPN2_045,17,7579911,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1726,26,1759,"0,0147811256",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,0,Damaging,"33,01","21,46"
"low bq, low freq, many artifacts, many samples",UPN2_047,17,7579911,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),4143,76,4235,"0,0179456907",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,0,Damaging,"33,55","20,54"
"low bq, low freq, many artifacts, many samples",UPN2_036,17,7579911,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),10832,111,10989,"0,0101010101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,0,Damaging,"34,1","19,05"
"low bq, low freq, many artifacts, many samples",UPN2_006,17,7579911,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1889,24,1917,"0,0125195618",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,0,Damaging,"33,8","16,58"
"low bq, low freq, many artifacts, many samples",UPN2_049,17,7579911,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3237,48,3298,"0,0145542753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,0,Damaging,"33,21","18,12"
"low bq, low freq, many artifacts, many samples",UPN2_050,17,7579911,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3068,36,3123,"0,0115273775",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,0,Damaging,"33,61","18,64"
"low bq, low freq, many artifacts, many samples",UPN2_051,17,7579911,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3533,43,3586,"0,0119910764",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,0,Damaging,"33,48","17,37"
"low bq, low freq, many artifacts, many samples",UPN2_052,17,7579911,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1982,24,2013,"0,0119225037",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,0,Damaging,"33,68","18,58"
"low bq, low freq, many artifacts, many samples",UPN2_038,17,7579911,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6158,70,6246,"0,0112071726",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,0,Damaging,"34,23","19,47"
"low bq, low freq, many artifacts, many samples",UPN2_053,17,7579911,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),4615,53,4688,"0,0113054608",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,0,Damaging,"33,38","20,19"
"low bq, low freq, many artifacts, many samples",UPN2_054,17,7579911,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3276,48,3345,"0,0143497758",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,0,Damaging,"33,57","19,06"
"low bq, low freq, many artifacts, many samples",UPN2_007,17,7579911,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),6648,76,6742,"0,0112726194",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,0,Damaging,"33,61","16,09"
"low bq, low freq, many artifacts, many samples",UPN2_008,17,7579911,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),9139,107,9294,"0,011512804",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,0,Damaging,"33,62","16,76"
"low bq, low freq, many artifacts, many samples",UPN2_009,17,7579911,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),7090,81,7196,"0,0112562535",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,0,Damaging,"33,53","15,73"
"low bq, low freq, many artifacts, many samples",UPN2_010,17,7579911,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),5584,77,5673,"0,0135730654",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,0,Damaging,"33,58","20,66"
"low bq, low freq, many artifacts, many samples",UPN2_011,17,7579911,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),4954,61,5027,"0,0121344738",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,0,Damaging,"33,71","17,23"
"low bq, low freq, many artifacts, many samples",UPN2_055,17,7579911,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3899,48,3956,"0,0121334681",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,0,Damaging,"33,51","18,42"
"low bq, low freq, many artifacts, many samples",UPN2_057,17,7579911,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3453,39,3509,"0,0111142776",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,0,Damaging,"33,32","16,26"
"low bq, low freq, many artifacts, many samples",UPN2_058,17,7579911,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),7370,106,7499,"0,014135218",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,0,Damaging,"33,49","19,06"
"low bq, low freq, many artifacts, many samples",UPN2_012,17,7579911,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),3072,36,3117,"0,0115495669",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,0,Damaging,"33,42","16,08"
"low bq, low freq, many artifacts",UPN2_013,17,7579911,A,T,start_lost(HIGH|MISSENSE|aTg/aAg|p.Met1?/c.2T>A|393|TP53|protein_coding|CODING|ENST00000269305|2|T),1829,23,1855,"0,0123989218",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,0,Damaging,"33,71","17,26"
"low freq, many artifacts",UPN2_048,17,7579923,C,A,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-11G>T|393|TP53|protein_coding|CODING|ENST00000269305|2|A),1685,20,1716,"0,0116550117",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"33,86","28,45"
"low freq, many artifacts",UPN2_010,17,74732902,C,T,missense_variant(MODERATE|MISSENSE|gGc/gAc|p.Gly114Asp/c.341G>A|221|SRSF2|protein_coding|CODING|ENST00000392485|1|T),1936,22,1960,"0,0112244898",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,34",Neutral,"0,413",Tolerated,"35,84",36
"low freq, many artifacts",UPN2_039,17,74732907,G,GC,frameshift_variant(HIGH||ggc/ggGc|p.Gly113fs/c.335dupG|221|SRSF2|protein_coding|CODING|ENST00000392485|1|GC),1539,22,1547,"0,014221073",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,54",NA
"low freq, many artifacts",UPN2_091,17,74732913,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr110*/c.330C>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),1787,22,1813,"0,0121345836",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,38","34,64"
"low freq, many artifacts",UPN2_056,17,74732914,T,A,missense_variant(MODERATE|MISSENSE|tAc/tTc|p.Tyr110Phe/c.329A>T|221|SRSF2|protein_coding|CODING|ENST00000392485|1|A),1997,21,2020,"0,0103960396",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,84",Neutral,"0,061",Tolerated,"34,71","30,81"
"inspected, many artifacts",UPN2_040,17,74732920,C,T,missense_variant(MODERATE|MISSENSE|cGc/cAc|p.Arg108His/c.323G>A|221|SRSF2|protein_coding|CODING|ENST00000392485|1|T),830,23,853,"0,0269636577",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,-1,Neutral,"0,034",Damaging,"35,54","34,35"
"low freq, many artifacts",UPN2_091,17,74732932,C,T,missense_variant(MODERATE|MISSENSE|gGa/gAa|p.Gly104Glu/c.311G>A|221|SRSF2|protein_coding|CODING|ENST00000392485|1|T),1790,20,1813,"0,0110314396",0,0,0,0,1,0,0,1,2,NO,NO,COSM4847468,cervix,1,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,"0,063",Tolerated,"35,77",36
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_014,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),5298,67,5371,"0,0124743996",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,"26,78","15,24"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_019,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4254,51,4311,"0,0118302018",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,"26,86","18,29"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_020,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),3238,38,3279,"0,0115888991",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,"26,62","14,55"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_023,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),5730,63,5802,"0,0108583247",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,"26,85","15,48"
"low bq, bad alignment, many samples",UPN2_041,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),24331,647,25022,"0,0258572456",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,"26,81","15,04"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_024,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2520,28,2552,"0,0109717868",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,"26,77","15,5"
"low bq, bad alignment, many samples",UPN2_042,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),11176,285,11493,"0,0247977029",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,"26,91","15,25"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_043,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),6286,118,6426,"0,0183629007",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,"26,72","14,64"
"low bq, many samples",UPN2_044,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),3326,79,3417,"0,0231196956",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,"27,07","14,7"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_029,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4256,46,4311,"0,0106703781",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,"26,9","15,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_031,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4335,46,4385,"0,0104903079",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,"26,65","15,24"
"low bq, bad alignment, many samples",UPN2_045,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),10013,237,10290,"0,02303207",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,"26,94","15,33"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_032,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2052,24,2079,"0,0115440115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,"26,99","15,21"
"low bq, bad alignment, many samples",UPN2_046,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),8383,207,8601,"0,024066969",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,"26,89","14,64"
"low bq, bad alignment, many samples",UPN2_047,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),11152,295,11461,"0,0257394643",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,"26,87","15,28"
"low bq, bad alignment, many samples",UPN2_048,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),12849,343,13232,"0,0259220073",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,"26,89","14,87"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_006,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1404,20,1427,"0,014015417",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,"26,78",14
"low bq, bad alignment, many samples",UPN2_049,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),6490,150,6665,"0,0225056264",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,"26,75","14,63"
"low bq, bad alignment, many samples",UPN2_050,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),6952,164,7136,"0,0229820628",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,"26,97","14,59"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_037,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),8813,97,8918,"0,0108768782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,"26,77","16,25"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),6474,142,6636,"0,0213984328",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,"26,9","15,78"
"low bq, low freq, many artifacts, many samples",UPN2_052,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),8417,186,8631,"0,0215502259",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,"27,28","15,59"
"low bq, many samples",UPN2_053,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),8094,192,8298,"0,0231381056",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,"27,05","14,65"
"low bq, bad alignment, many samples",UPN2_054,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4332,107,4455,"0,0240179574",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,"26,85","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_007,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),5622,63,5693,"0,0110662217",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,"27,09","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_008,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),10513,124,10643,"0,0116508503",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,"27,06","15,8"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_011,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4498,56,4556,"0,0122914838",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,"26,88","16,7"
"low bq, many samples",UPN2_055,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),10281,240,10536,"0,0227790433",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,"27,04","14,98"
"low bq, many samples",UPN2_056,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),3867,89,3960,"0,0224747475",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,"27,01","14,98"
"low bq, bad alignment, many samples",UPN2_057,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),5665,132,5814,"0,0227038184",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,"26,94","14,45"
"low bq, bad alignment, many samples",UPN2_058,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),5901,150,6054,"0,0247770069",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,"26,92","15,19"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_012,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2490,30,2526,"0,0118764846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,"26,81","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_013,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1478,21,1499,"0,0140093396",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,"27,15","17,57"
"low bq, low freq, many artifacts, many samples",UPN2_091,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),3507,44,3576,"0,0123042506",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,"27,01","15,3"
"low bq, bad alignment, many samples",UPN2_061,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),724,25,756,"0,0330687831",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,"26,47","16,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1025,22,1049,"0,0209723546",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,"26,5","14,64"
"low bq, bad alignment, many samples",UPN2_081,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1385,40,1425,"0,0280701754",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,"26,69","14,55"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_094,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),3674,45,3722,"0,012090274",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,"26,88","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_101,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2445,37,2486,"0,0148833467",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,"27,19","19,49"
"low bq, low freq, many artifacts, many samples",UPN2_102,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2627,31,2658,"0,0116629044",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,"27,11","14,23"
"low freq, many artifacts, many samples",UPN2_107,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),5563,68,5639,"0,0120588757",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,27,"15,47"
"low bq, low freq, many artifacts",UPN2_109,17,74732935,C,G,missense_variant(MODERATE|MISSENSE|cGg/cCg|p.Arg103Pro/c.308G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4415,45,4468,"0,0100716204",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,3,Damaging,"27,05","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_054,17,74732942,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser101Arg/c.301A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4393,46,4475,"0,0102793296",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,79",Neutral,413,Tolerated,"28,68","14,96"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,17,74732942,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser101Arg/c.301A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1036,20,1060,"0,0188679245",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,79",Neutral,413,Tolerated,"26,52",14
"low bq, low freq, many artifacts, many samples",UPN2_081,17,74732942,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser101Arg/c.301A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1410,20,1435,"0,0139372822",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,79",Neutral,413,Tolerated,"27,88",14
"low bq, low freq, many artifacts, many samples",UPN2_011,17,74732944,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His100Pro/c.299A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4527,46,4587,"0,010028341",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,45,Damaging,"27,88",14
"low bq, bad alignment, many samples",UPN2_062,17,74732944,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His100Pro/c.299A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1026,28,1060,"0,0264150943",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,45,Damaging,"26,66","15,57"
"low bq, low freq, many artifacts, many samples",UPN2_081,17,74732944,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His100Pro/c.299A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1391,24,1435,"0,0167247387",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,45,Damaging,"27,4","14,83"
"low bq, low freq, many artifacts",UPN2_105,17,74732944,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His100Pro/c.299A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2607,28,2653,"0,0105540897",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,45,Damaging,"29,93",14
"low freq, many artifacts",UPN2_089,17,74732945,G,A,missense_variant(MODERATE|MISSENSE|Cac/Tac|p.His100Tyr/c.298C>T|221|SRSF2|protein_coding|CODING|ENST00000392485|1|A),3339,35,3377,"0,0103642286",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,352,Tolerated,"33,65","32,57"
"low freq, many artifacts",UPN2_056,17,74732947,T,A,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His99Leu/c.296A>T|221|SRSF2|protein_coding|CODING|ENST00000392485|1|A),3909,47,4003,"0,0117411941",0,0,0,0,1,0,0,1,2,NO,NO,COSM1577283,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,"-1,9",Neutral,"0,332",Tolerated,"29,04","32,74"
"low bq, low freq, many artifacts, many samples",UPN2_001,17,74732947,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His99Pro/c.296A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1932,21,1959,"0,010719755",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,195,Tolerated,"27,64","16,1"
"low bq, low freq, many artifacts, many samples",UPN2_042,17,74732947,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His99Pro/c.296A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),11370,127,11550,"0,010995671",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,195,Tolerated,"29,02","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_045,17,74732947,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His99Pro/c.296A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),10156,108,10359,"0,0104257168",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,195,Tolerated,"29,11","14,06"
"low bq, low freq, many artifacts, many samples",UPN2_047,17,74732947,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His99Pro/c.296A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),11345,141,11541,"0,0122173122",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,195,Tolerated,"29,07","16,89"
"low bq, low freq, many artifacts, many samples",UPN2_050,17,74732947,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His99Pro/c.296A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),7045,78,7176,"0,0108695652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,195,Tolerated,"28,83","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_053,17,74732947,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His99Pro/c.296A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),8219,87,8358,"0,0104091888",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,195,Tolerated,"28,97","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_054,17,74732947,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His99Pro/c.296A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4413,50,4477,"0,011168193",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,195,Tolerated,"28,75","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_055,17,74732947,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His99Pro/c.296A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),10422,118,10615,"0,0111163448",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,195,Tolerated,"28,75","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_057,17,74732947,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His99Pro/c.296A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),5732,63,5841,"0,0107858243",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,195,Tolerated,"28,8","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_091,17,74732947,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His99Pro/c.296A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),3553,44,3605,"0,0122052705",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,195,Tolerated,"30,05","14,45"
"low bq, many samples",UPN2_062,17,74732947,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His99Pro/c.296A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1027,27,1060,"0,0254716981",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,195,Tolerated,"27,27",14
"low bq, many samples",UPN2_075,17,74732947,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His99Pro/c.296A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),751,28,785,"0,0356687898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,195,Tolerated,"27,4","14,64"
"low bq, many samples",UPN2_081,17,74732947,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His99Pro/c.296A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1394,34,1432,"0,0237430168",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,195,Tolerated,"27,65","15,41"
"low bq, low freq, many artifacts, many samples",UPN2_098,17,74732947,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His99Pro/c.296A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),3054,34,3108,"0,0109395109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,195,Tolerated,"30,04","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_100,17,74732947,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His99Pro/c.296A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2742,31,2787,"0,0111230714",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,195,Tolerated,"29,9","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_104,17,74732947,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His99Pro/c.296A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),3356,43,3405,"0,0126284875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,195,Tolerated,"29,78","15,95"
"low bq, low freq, many artifacts, many samples",UPN2_106,17,74732947,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His99Pro/c.296A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),6345,70,6442,"0,0108661906",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,195,Tolerated,"29,88","14,37"
"low bq, low freq, many artifacts",UPN2_107,17,74732947,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His99Pro/c.296A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),5584,58,5663,"0,0102419212",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,195,Tolerated,"29,72","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_041,17,74732953,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp97Ala/c.290A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),24827,327,25239,"0,0129561393",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,03",Damaging,"28,99","15,63"
"low bq, low freq, many artifacts, many samples",UPN2_042,17,74732953,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp97Ala/c.290A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),11372,151,11559,"0,0130634138",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,03",Damaging,"28,83","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_043,17,74732953,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp97Ala/c.290A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),6389,84,6501,"0,0129210891",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,03",Damaging,"29,15","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_046,17,74732953,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp97Ala/c.290A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),8522,87,8663,"0,0100427104",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,03",Damaging,"28,82","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_047,17,74732953,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp97Ala/c.290A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),11355,136,11547,"0,011777951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,03",Damaging,"28,88","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_048,17,74732953,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp97Ala/c.290A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),13139,163,13349,"0,0122106525",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,03",Damaging,"28,99","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_049,17,74732953,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp97Ala/c.290A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),6603,77,6712,"0,0114719905",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,03",Damaging,"28,76","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_050,17,74732953,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp97Ala/c.290A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),7062,88,7178,"0,0122596824",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,03",Damaging,"28,52","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_051,17,74732953,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp97Ala/c.290A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),6595,76,6698,"0,0113466706",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,03",Damaging,"29,06","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_052,17,74732953,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp97Ala/c.290A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),8549,102,8680,"0,0117511521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,03",Damaging,"28,59",14
"low bq, low freq, many artifacts, many samples",UPN2_053,17,74732953,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp97Ala/c.290A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),8230,95,8358,"0,0113663556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,03",Damaging,"28,92","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_054,17,74732953,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp97Ala/c.290A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4410,51,4479,"0,0113864702",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,03",Damaging,"28,72","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_011,17,74732953,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp97Ala/c.290A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4527,50,4589,"0,01089562",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,03",Damaging,"28,46","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_055,17,74732953,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp97Ala/c.290A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),10435,128,10622,"0,0120504613",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,03",Damaging,"28,7","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_056,17,74732953,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp97Ala/c.290A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),3947,42,4003,"0,0104921309",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,03",Damaging,"28,82",14
"low bq, low freq, many artifacts, many samples",UPN2_090,17,74732953,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp97Ala/c.290A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),3365,38,3408,"0,0111502347",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,03",Damaging,"29,34",14
"low bq, low freq, many artifacts, many samples",UPN2_057,17,74732953,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp97Ala/c.290A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),5754,68,5844,"0,0116358658",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,03",Damaging,"28,75","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_058,17,74732953,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp97Ala/c.290A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),5946,73,6071,"0,0120243782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,03",Damaging,"29,02","14,1"
"low bq, low freq, many artifacts, many samples",UPN2_093,17,74732953,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp97Ala/c.290A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1635,24,1661,"0,014449127",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,03",Damaging,"29,38",14
"low bq, many samples",UPN2_062,17,74732953,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp97Ala/c.290A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1027,31,1060,"0,029245283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,03",Damaging,"27,13","15,42"
"low bq, many samples",UPN2_081,17,74732953,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp97Ala/c.290A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1393,36,1435,"0,025087108",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,03",Damaging,"27,51",14
"low bq, low freq, many artifacts, many samples",UPN2_095,17,74732953,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp97Ala/c.290A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),3581,43,3634,"0,0118326912",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,03",Damaging,"29,46","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_096,17,74732953,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp97Ala/c.290A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),3648,44,3698,"0,0118983234",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,03",Damaging,"29,31",14
"low bq, low freq, many artifacts, many samples",UPN2_099,17,74732953,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp97Ala/c.290A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1541,24,1573,"0,0152574698",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,03",Damaging,"28,75",14
"low bq, low freq, many artifacts, many samples",UPN2_100,17,74732953,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp97Ala/c.290A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2747,32,2787,"0,0114818802",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,03",Damaging,"29,22","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_102,17,74732953,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp97Ala/c.290A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2642,35,2683,"0,0130450988",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,03",Damaging,"29,19",14
"low bq, low freq, many artifacts, many samples",UPN2_103,17,74732953,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp97Ala/c.290A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2470,26,2508,"0,0103668262",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,03",Damaging,"29,1","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_105,17,74732953,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp97Ala/c.290A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2607,36,2653,"0,0135695439",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,03",Damaging,"29,11",14
"low bq, low freq, many artifacts, many samples",UPN2_106,17,74732953,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp97Ala/c.290A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),6330,83,6443,"0,0128821977",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,03",Damaging,"29,2","14,08"
"low bq, low freq, many artifacts, many samples",UPN2_107,17,74732953,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp97Ala/c.290A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),5587,57,5664,"0,0100635593",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,03",Damaging,"29,25","15,02"
"low bq, low freq, many artifacts",UPN2_108,17,74732953,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp97Ala/c.290A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4686,63,4761,"0,0132325142",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,76",Neutral,"0,03",Damaging,"29,34","14,7"
"many samples, homopolymer 6G, ins and del",UPN2_001,17,74732955,C,CG,frameshift_variant(HIGH||ccg/ccCg|p.Asp97fs/c.287dupC|221|SRSF2|protein_coding|CODING|ENST00000392485|1|CG),1954,20,1967,"0,0101677682",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,83",NA
"many samples, homopolymer 6G, ins and del",UPN2_035,17,74732955,C,CG,frameshift_variant(HIGH||ccg/ccCg|p.Asp97fs/c.287dupC|221|SRSF2|protein_coding|CODING|ENST00000392485|1|CG),4707,70,4725,"0,0148148148",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,1",NA
"inspected, different deletion",UPN2_036,17,74732955,C,CG,frameshift_variant(HIGH||ccg/ccCg|p.Asp97fs/c.287dupC|221|SRSF2|protein_coding|CODING|ENST00000392485|1|CG),2929,177,2938,"0,0602450647",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,92",NA
"inspected, many samples, homopolymer 6G, ins and del",UPN2_039,17,74732955,C,CG,frameshift_variant(HIGH||ccg/ccCg|p.Asp97fs/c.287dupC|221|SRSF2|protein_coding|CODING|ENST00000392485|1|CG),3073,111,3078,"0,0360623782",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,99",NA
"many samples, homopolymer 6G, ins and del",UPN2_040,17,74732955,C,CG,frameshift_variant(HIGH||ccg/ccCg|p.Asp97fs/c.287dupC|221|SRSF2|protein_coding|CODING|ENST00000392485|1|CG),1687,50,1695,"0,0294985251",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,01",NA
"many samples, homopolymer 6G, ins and del",UPN2_095,17,74732955,C,CG,frameshift_variant(HIGH||ccg/ccCg|p.Asp97fs/c.287dupC|221|SRSF2|protein_coding|CODING|ENST00000392485|1|CG),3630,37,3637,"0,0101732197",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,45",NA
"inspected, different deletion",UPN2_036,17,74732955,C,CGG,frameshift_variant(HIGH||ccg/ccCCg|p.Asp97fs/c.286_287dupCC|221|SRSF2|protein_coding|CODING|ENST00000392485|1|CGG),2929,38,2938,"0,0129339687",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,92",NA
"homopolymer 6G, low freq, many samples",UPN2_001,17,74732955,CG,C,frameshift_variant(HIGH||ccg/|p.Pro96fs/c.287delC|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),1930,36,1967,"0,0183019827",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,04",NA
"homopolymer 6G, low freq, many samples",UPN2_018,17,74732955,CG,C,frameshift_variant(HIGH||ccg/|p.Pro96fs/c.287delC|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),4184,46,4252,"0,0108184384",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,16",NA
"homopolymer 6G, low freq, many samples",UPN2_042,17,74732955,CG,C,frameshift_variant(HIGH||ccg/|p.Pro96fs/c.287delC|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),11400,120,11581,"0,0103617995",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,2",NA
"inspected, homopolymer 6G, low freq, many samples",UPN2_044,17,74732955,CG,C,frameshift_variant(HIGH||ccg/|p.Pro96fs/c.287delC|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),3365,58,3436,"0,0168800931",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,34",NA
"homopolymer 6G, low freq, many samples",UPN2_030,17,74732955,CG,C,frameshift_variant(HIGH||ccg/|p.Pro96fs/c.287delC|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),5880,87,5989,"0,0145266322",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,14",NA
"homopolymer 6G, low freq, many samples",UPN2_045,17,74732955,CG,C,frameshift_variant(HIGH||ccg/|p.Pro96fs/c.287delC|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),10198,118,10376,"0,0113723978",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,26",NA
"homopolymer 6G, low freq, many samples",UPN2_033,17,74732955,CG,C,frameshift_variant(HIGH||ccg/|p.Pro96fs/c.287delC|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),4504,54,4585,"0,0117775354",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,24",NA
"homopolymer 6G, low freq, many samples",UPN2_034,17,74732955,CG,C,frameshift_variant(HIGH||ccg/|p.Pro96fs/c.287delC|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),1578,20,1598,"0,0125156446",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,2",NA
"homopolymer 6G, low freq, many samples",UPN2_047,17,74732955,CG,C,frameshift_variant(HIGH||ccg/|p.Pro96fs/c.287delC|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),11384,143,11570,"0,0123595506",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,19",NA
"homopolymer 6G, low freq, many samples",UPN2_050,17,74732955,CG,C,frameshift_variant(HIGH||ccg/|p.Pro96fs/c.287delC|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),7064,89,7184,"0,0123886414",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,38",NA
"homopolymer 6G, low freq, many samples",UPN2_054,17,74732955,CG,C,frameshift_variant(HIGH||ccg/|p.Pro96fs/c.287delC|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),4415,52,4481,"0,0116045526",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,33",NA
"homopolymer 6G, low freq, many samples",UPN2_011,17,74732955,CG,C,frameshift_variant(HIGH||ccg/|p.Pro96fs/c.287delC|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),4535,50,4595,"0,0108813928",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,91",NA
"homopolymer 6G, low freq, many samples",UPN2_090,17,74732955,CG,C,frameshift_variant(HIGH||ccg/|p.Pro96fs/c.287delC|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),3369,40,3413,"0,0117198945",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,87",NA
"homopolymer 6G, low freq, many samples",UPN2_057,17,74732955,CG,C,frameshift_variant(HIGH||ccg/|p.Pro96fs/c.287delC|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),5758,64,5847,"0,0109457842",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,26",NA
"homopolymer 6G, low freq, many samples",UPN2_058,17,74732955,CG,C,frameshift_variant(HIGH||ccg/|p.Pro96fs/c.287delC|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),5959,69,6076,"0,0113561554",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,24",NA
"homopolymer 6G, low freq, many samples",UPN2_091,17,74732955,CG,C,frameshift_variant(HIGH||ccg/|p.Pro96fs/c.287delC|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),3536,60,3606,"0,0166389351",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,66",NA
"homopolymer 6G, low freq, many samples",UPN2_092,17,74732955,CG,C,frameshift_variant(HIGH||ccg/|p.Pro96fs/c.287delC|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),1322,22,1351,"0,0162842339",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,86",NA
"homopolymer 6G, low freq, many samples",UPN2_071,17,74732955,CG,C,frameshift_variant(HIGH||ccg/|p.Pro96fs/c.287delC|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),816,36,854,"0,0421545667",1,0,0,1,0,0,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,01",NA
"homopolymer 6G, low freq, many samples",UPN2_095,17,74732955,CG,C,frameshift_variant(HIGH||ccg/|p.Pro96fs/c.287delC|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),3591,37,3639,"0,0101676285",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,68",NA
"homopolymer 6G, low freq, many samples",UPN2_099,17,74732955,CG,C,frameshift_variant(HIGH||ccg/|p.Pro96fs/c.287delC|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),1542,22,1574,"0,0139771283",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,81",NA
"homopolymer 6G, low freq, many samples",UPN2_100,17,74732955,CG,C,frameshift_variant(HIGH||ccg/|p.Pro96fs/c.287delC|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),2755,29,2791,"0,010390541",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,98",NA
"homopolymer 6G, low freq, many samples",UPN2_107,17,74732955,CG,C,frameshift_variant(HIGH||ccg/|p.Pro96fs/c.287delC|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),5576,64,5672,"0,0112834979",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,82",NA
"homopolymer 6G, low freq, many samples",UPN2_111,17,74732955,CG,C,frameshift_variant(HIGH||ccg/|p.Pro96fs/c.287delC|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),3549,38,3593,"0,0105761202",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,85",NA
"Hotspot, inspected, many artifacts, low freq",UPN2_044,17,74732959,G,A,missense_variant(MODERATE|MISSENSE|cCc/cTc|p.Pro95Leu/c.284C>T|221|SRSF2|protein_coding|CODING|ENST00000392485|1|A),3368,66,3436,"0,0192083818",0,0,0,0,0,1,0,1,2,NO,NO,COSM146288,haematopoietic_and_lymphoid_tissue,93,NO,NO,NO,NO,NO,NO,"-5,95",Deleterious,"0,002",Damaging,"34,41","31,7"
"low freq, many artifacts",UPN2_012,17,74732966,C,T,missense_variant(MODERATE|MISSENSE|Ggc/Agc|p.Gly93Ser/c.277G>A|221|SRSF2|protein_coding|CODING|ENST00000392485|1|T),2500,34,2538,"0,0133963751",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,"0,016",Damaging,"34,62","30,26"
"low bq, many samples",UPN2_062,17,74732969,A,C,missense_variant(MODERATE|MISSENSE|Tac/Gac|p.Tyr92Asp/c.274T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),1034,26,1060,"0,0245283019",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,86",Deleterious,182,Tolerated,"29,38","14,77"
"low bq, many samples",UPN2_071,17,74732969,A,C,missense_variant(MODERATE|MISSENSE|Tac/Gac|p.Tyr92Asp/c.274T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),806,30,855,"0,0350877193",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,86",Deleterious,182,Tolerated,"29,13","15,43"
"low bq, many samples",UPN2_081,17,74732969,A,C,missense_variant(MODERATE|MISSENSE|Tac/Gac|p.Tyr92Asp/c.274T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),1386,49,1441,"0,0340041638",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,86",Deleterious,182,Tolerated,"29,17","19,18"
"low bq, many samples",UPN2_075,17,74732976,C,T,missense_variant(MODERATE|MISSENSE|atG/atA|p.Met89Ile/c.267G>A|221|SRSF2|protein_coding|CODING|ENST00000392485|1|T),766,22,788,"0,0279187817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,"0,14",Tolerated,"30,49","25,18"
"low bq, many samples",UPN2_062,17,74732977,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met89Arg/c.266T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),1027,30,1060,"0,0283018868",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,48",Deleterious,53,Tolerated,"27,66","15,1"
low bq,UPN2_075,17,74732977,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met89Arg/c.266T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),767,20,788,"0,0253807107",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,48",Deleterious,53,Tolerated,"27,85",14
"low bq, low freq, many artifacts",UPN2_054,17,74732977,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met89Lys/c.266T>A|221|SRSF2|protein_coding|CODING|ENST00000392485|1|T),4389,60,4481,"0,0133898683",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,48",Deleterious,"0,029",Damaging,29,"25,6"
"low bq, low freq, many artifacts",UPN2_057,17,74732977,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met89Lys/c.266T>A|221|SRSF2|protein_coding|CODING|ENST00000392485|1|T),5747,64,5849,"0,0109420414",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,48",Deleterious,29,Damaging,"29,21","24,66"
"low bq, low freq, many artifacts, many samples",UPN2_014,17,74732978,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met89Leu/c.265A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),5317,56,5400,"0,0103703704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,94,Tolerated,"27,33","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_018,17,74732978,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met89Leu/c.265A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4188,46,4249,"0,0108260767",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,94,Tolerated,"27,14",14
"low bq, low freq, many artifacts, many samples",UPN2_020,17,74732978,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met89Leu/c.265A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),3250,33,3297,"0,0100090992",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,94,Tolerated,"27,34",14
"low bq, low freq, many artifacts, many samples",UPN2_025,17,74732978,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met89Leu/c.265A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),7676,81,7794,"0,0103926097",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,94,Tolerated,"27,17",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_026,17,74732978,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met89Leu/c.265A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),6871,72,6991,"0,0102989558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,94,Tolerated,"26,75","14,97"
"low freq, many artifacts, many samples",UPN2_031,17,74732978,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met89Leu/c.265A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4348,47,4415,"0,0106455266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,94,Tolerated,27,14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_037,17,74732978,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met89Leu/c.265A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),8798,96,8955,"0,010720268",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,94,Tolerated,"26,74","14,65"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_038,17,74732978,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met89Leu/c.265A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),9817,102,9961,"0,0102399357",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,94,Tolerated,"26,98","17,12"
"low bq, bad alignment, many samples",UPN2_061,17,74732978,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met89Leu/c.265A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),743,27,772,"0,0349740933",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,94,Tolerated,"25,41","14,67"
"low bq, bad alignment, many samples",UPN2_062,17,74732978,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met89Leu/c.265A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1021,35,1060,"0,0330188679",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,94,Tolerated,"25,19","14,63"
"low bq, bad alignment, many samples",UPN2_071,17,74732978,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met89Leu/c.265A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),821,28,854,"0,0327868852",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,94,Tolerated,"25,76",14
"low bq, bad alignment, many samples",UPN2_081,17,74732978,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met89Leu/c.265A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1375,57,1441,"0,039555864",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,94,Tolerated,"25,98","14,89"
"low bq, bad alignment",UPN2_083,17,74732978,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met89Leu/c.265A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),519,31,550,"0,0563636364",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,78",Neutral,94,Tolerated,"25,92","14,84"
"low bq, low freq, many artifacts",UPN2_090,17,74732981,G,A,stop_gained(HIGH|NONSENSE|Caa/Taa|p.Gln88*/c.262C>T|221|SRSF2|protein_coding|CODING|ENST00000392485|1|A),3373,36,3412,"0,0105509965",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,14","28,47"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_001,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),1918,32,1967,"0,0162684291",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"24,41",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_015,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),7960,84,8111,"0,0103563063",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"24,97","14,52"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_017,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),2672,29,2721,"0,0106578464",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,04",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_021,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),3652,43,3731,"0,0115250603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,17","16,98"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_002,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),2406,35,2459,"0,0142334282",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"24,5",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_041,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),24536,443,25258,"0,0175389975",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,22","14,15"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_024,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),2520,31,2565,"0,01208577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,07",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_025,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),7654,81,7793,"0,0103939433",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,09","14,09"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_026,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),6858,76,6990,"0,0108726753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,05","14,75"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_027,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),5728,74,5836,"0,0126799178",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,05",14
"low bq, bad alignment, many samples",UPN2_089,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),3266,99,3378,"0,0293072824",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"26,37","14,25"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),11256,202,11570,"0,0174589455",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,16","14,07"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_043,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),6319,117,6509,"0,0179751114",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,26","14,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_044,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),3354,52,3435,"0,0151382824",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,21","14,73"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_029,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),4257,47,4343,"0,0108220124",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,16","14,94"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_030,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),5862,67,5989,"0,0111871765",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,08","14,6"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),10085,185,10370,"0,0178399229",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,18",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),8424,166,8680,"0,019124424",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,11","14,31"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_033,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),4507,46,4584,"0,010034904",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,11",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_034,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),1568,23,1598,"0,0143929912",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"24,78","15,91"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),11221,211,11563,"0,0182478596",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,1","14,06"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_048,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),13032,233,13366,"0,0174322909",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,15","14,36"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_035,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),4626,51,4726,"0,0107913669",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,03",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_036,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),3539,49,3614,"0,0135583841",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,45","18,24"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),6540,118,6716,"0,0175699821",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,15",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),6997,110,7183,"0,0153139357",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,01","14,86"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_037,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),8795,100,8954,"0,011168193",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"24,94","14,35"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),6548,99,6705,"0,0147651007",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,14",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),8491,129,8685,"0,0148531952",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,07","14,34"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_038,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),9753,128,9960,"0,0128514056",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,04","14,16"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_039,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),3016,33,3080,"0,0107142857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,04",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),8163,135,8365,"0,016138673",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,03","14,15"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),4340,82,4481,"0,0182994867",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,1","14,09"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_007,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),5603,101,5743,"0,0175866272",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"24,78","14,07"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_008,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),10436,164,10679,"0,0153572432",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"24,59","14,12"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_009,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),7999,115,8195,"0,0140329469",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"24,71","14,52"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_010,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),3833,46,3895,"0,0118100128",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"24,56",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_011,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),4468,73,4596,"0,0158833768",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"24,63",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),10328,185,10630,"0,0174035748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,25,"14,34"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),3900,65,4005,"0,0162297129",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,17",14
"low bq, bad alignment, many samples",UPN2_090,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),3308,97,3411,"0,0284374084",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"26,41","14,14"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),5631,119,5849,"0,0203453582",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,26","14,24"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_058,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),5908,105,6078,"0,0172754195",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,13","14,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_012,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),2465,45,2536,"0,0177444795",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"24,62","15,87"
"low bq, bad alignment, many samples",UPN2_060,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),282,32,314,"0,101910828",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,45","14,41"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_040,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),1661,20,1695,"0,01179941",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"24,99",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_013,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),1477,20,1511,"0,0132362674",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"24,82",14
"low bq, bad alignment, many samples",UPN2_091,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),3476,109,3605,"0,0302357836",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"26,2",14
"low bq, bad alignment, many samples",UPN2_092,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),1310,35,1351,"0,0259067358",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"26,45","14,89"
"low bq, bad alignment, many samples",UPN2_093,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),1608,41,1661,"0,0246839253",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"26,39",14
"low bq, bad alignment, many samples",UPN2_061,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),693,76,772,"0,0984455959",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,52","14,26"
"low bq, bad alignment, many samples",UPN2_062,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),955,105,1060,"0,0990566038",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,37","14,5"
"low bq, bad alignment, many samples",UPN2_063,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),383,52,436,"0,119266055",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,81","14,35"
"low bq, bad alignment, many samples",UPN2_064,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),259,26,286,"0,0909090909",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,89",15
"low bq, bad alignment, many samples",UPN2_068,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),234,27,262,"0,1030534351",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,48","14,26"
"low bq, bad alignment, many samples",UPN2_071,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),772,76,853,"0,0890973036",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,44","14,51"
"low bq, bad alignment, many samples",UPN2_072,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),544,41,588,"0,0697278912",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,15","14,8"
"low bq, bad alignment, many samples",UPN2_075,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),706,78,788,"0,0989847716",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,76","14,23"
"low bq, bad alignment, many samples",UPN2_076,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),273,34,309,"0,1100323625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,96","14,76"
"low bq, bad alignment, many samples",UPN2_077,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),245,28,278,"0,1007194245",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"26,07","14,93"
"low bq, bad alignment, many samples",UPN2_078,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),492,56,557,"0,1005385996",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,55","14,68"
"low bq, bad alignment, many samples",UPN2_080,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),523,43,569,"0,0755711775",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,64","14,16"
"low bq, bad alignment, many samples",UPN2_081,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),1307,122,1441,"0,0846634282",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,62","14,43"
"low bq, bad alignment, many samples",UPN2_082,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),179,27,207,"0,1304347826",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,91","14,48"
"low bq, bad alignment, many samples",UPN2_083,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),484,66,550,"0,12",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,5","14,39"
"low bq, bad alignment, many samples",UPN2_084,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),303,33,338,"0,0976331361",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"26,44","14,55"
"low bq, bad alignment, many samples",UPN2_085,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),207,23,231,"0,0995670996",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,83",14
"low bq, bad alignment, many samples",UPN2_087,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),218,29,249,"0,1164658635",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,69",14
"low bq, bad alignment, many samples",UPN2_094,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),3618,116,3747,"0,0309580998",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"26,37","14,06"
"low bq, bad alignment, many samples",UPN2_095,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),3495,126,3638,"0,0346344145",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"26,49","14,43"
"low bq, bad alignment, many samples",UPN2_096,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),3580,103,3702,"0,0278227985",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"26,2","14,45"
"low bq, bad alignment, many samples",UPN2_097,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),4018,126,4175,"0,0301796407",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"26,32","14,1"
"low bq, bad alignment, many samples",UPN2_098,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),3032,75,3114,"0,0240847784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"26,25","14,27"
"low bq, bad alignment, many samples",UPN2_099,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),1520,49,1574,"0,0311308767",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"25,99","14,14"
"low bq, bad alignment, many samples",UPN2_100,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),2689,91,2790,"0,0326164875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"26,22",14
"low bq, bad alignment, many samples",UPN2_101,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),2415,73,2499,"0,0292116847",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"26,55","14,18"
"low bq, bad alignment, many samples",UPN2_102,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),2596,73,2685,"0,0271880819",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"26,14","14,19"
"low bq, bad alignment, many samples",UPN2_103,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),2433,66,2511,"0,0262843489",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"26,17","14,32"
"low bq, bad alignment, many samples",UPN2_104,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),3301,82,3411,"0,024039871",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"26,1","14,54"
"low bq, bad alignment, many samples",UPN2_105,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),2555,88,2660,"0,0330827068",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"26,24","14,23"
"low bq, bad alignment, many samples",UPN2_106,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),6232,170,6445,"0,0263770365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"26,26","14,19"
"low bq, bad alignment, many samples",UPN2_107,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),5496,149,5666,"0,0262972114",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"26,16","14,4"
"low bq, bad alignment, many samples",UPN2_108,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),4593,140,4767,"0,0293685756",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"26,24","14,39"
"low bq, bad alignment, many samples",UPN2_109,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),4337,132,4486,"0,0294248774",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"26,31","14,63"
"low bq, bad alignment, many samples",UPN2_110,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),4615,117,4755,"0,0246056782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"26,32","14,49"
"low bq, bad alignment",UPN2_111,17,74732983,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val87Gly/c.260T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),3461,121,3590,"0,0337047354",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,0,Damaging,"26,35","14,27"
"low bq, low freq, many artifacts",UPN2_032,17,74732983,A,G,missense_variant(MODERATE|MISSENSE|gTg/gCg|p.Val87Ala/c.260T>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2057,22,2103,"0,0104612458",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,26",Deleterious,"0,016",Damaging,"24,79","28,32"
"low bq, low freq, many artifacts",UPN2_011,17,74732983,A,G,missense_variant(MODERATE|MISSENSE|gTg/gCg|p.Val87Ala/c.260T>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4468,46,4596,"0,0100087032",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,26",Deleterious,"0,016",Damaging,"24,63","27,33"
"low freq, many artifacts",UPN2_006,17,74732983,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val87Glu/c.260T>A|221|SRSF2|protein_coding|CODING|ENST00000392485|1|T),1392,20,1433,"0,0139567341",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,06",Deleterious,0,Damaging,"24,55","31,65"
"low bq, low freq, many artifacts",UPN2_044,17,74732987,G,A,missense_variant(MODERATE|MISSENSE|Cgg/Tgg|p.Arg86Trp/c.256C>T|221|SRSF2|protein_coding|CODING|ENST00000392485|1|A),3346,82,3435,"0,0238719068",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,93",Deleterious,"0,002",Damaging,"34,64","25,16"
"low bq, low freq, many artifacts, many samples",UPN2_002,17,74732989,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu85Arg/c.254T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),2420,25,2459,"0,0101667344",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"27,05","16,12"
"low bq, low freq, many artifacts, many samples",UPN2_089,17,74732989,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu85Arg/c.254T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),3323,42,3378,"0,0124333925",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"30,12","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_045,17,74732989,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu85Arg/c.254T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),10191,105,10370,"0,0101253616",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"28,63","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_047,17,74732989,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu85Arg/c.254T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),11365,119,11562,"0,010292337",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"28,59","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_054,17,74732989,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu85Arg/c.254T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),4394,51,4481,"0,0113813881",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"28,52",14
"low bq, low freq, many artifacts, many samples",UPN2_008,17,74732989,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu85Arg/c.254T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),10511,107,10679,"0,0100196648",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"27,04","14,07"
"low bq, low freq, many artifacts, many samples",UPN2_011,17,74732989,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu85Arg/c.254T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),4507,50,4594,"0,0108837614",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"27,15","15,94"
"low bq, low freq, many artifacts, many samples",UPN2_040,17,74732989,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu85Arg/c.254T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),1667,21,1695,"0,0123893805",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"27,92","20,1"
"low bq, low freq, many artifacts, many samples",UPN2_091,17,74732989,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu85Arg/c.254T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),3544,52,3605,"0,0144244105",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"30,28","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_093,17,74732989,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu85Arg/c.254T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),1638,21,1661,"0,0126429862",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"30,54",14
"low bq, many samples",UPN2_061,17,74732989,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu85Arg/c.254T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),732,37,773,"0,0478654592",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"28,49","15,03"
"low bq, many samples",UPN2_062,17,74732989,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu85Arg/c.254T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),1021,35,1060,"0,0330188679",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"27,92","14,57"
"low bq, many samples",UPN2_063,17,74732989,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu85Arg/c.254T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),407,28,436,"0,0642201835",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"28,66","14,46"
"low bq, many samples",UPN2_071,17,74732989,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu85Arg/c.254T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),807,45,853,"0,0527549824",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"28,24","14,29"
"low bq, many samples",UPN2_072,17,74732989,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu85Arg/c.254T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),554,32,588,"0,0544217687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"28,42","16,47"
"low bq, many samples",UPN2_075,17,74732989,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu85Arg/c.254T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),753,32,788,"0,0406091371",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"27,82","14,81"
"low bq, many samples",UPN2_078,17,74732989,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu85Arg/c.254T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),528,28,557,"0,0502692998",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"28,27","15,18"
"low bq, many samples",UPN2_080,17,74732989,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu85Arg/c.254T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),545,24,569,"0,0421792619",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"28,51","14,54"
"low bq, many samples",UPN2_081,17,74732989,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu85Arg/c.254T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),1368,67,1441,"0,0464954892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"28,41","15,54"
"low bq, many samples",UPN2_083,17,74732989,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu85Arg/c.254T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),510,38,550,"0,0690909091",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"28,6","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_094,17,74732989,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu85Arg/c.254T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),3673,52,3746,"0,0138814736",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"30,29","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_096,17,74732989,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu85Arg/c.254T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),3650,45,3702,"0,0121555916",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"30,48","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_098,17,74732989,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu85Arg/c.254T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),3062,38,3114,"0,0122029544",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"30,29",14
"low bq, low freq, many artifacts, many samples",UPN2_100,17,74732989,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu85Arg/c.254T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),2746,41,2791,"0,0146900752",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"30,36","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_101,17,74732989,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu85Arg/c.254T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),2460,27,2499,"0,0108043217",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"30,13",14
"low bq, low freq, many artifacts, many samples",UPN2_102,17,74732989,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu85Arg/c.254T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),2644,33,2685,"0,0122905028",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"30,35","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_103,17,74732989,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu85Arg/c.254T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),2465,30,2510,"0,0119521912",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"30,43","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_104,17,74732989,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu85Arg/c.254T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),3358,44,3411,"0,012899443",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"30,43","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_105,17,74732989,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu85Arg/c.254T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),2613,36,2661,"0,0135287486",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"30,17","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_106,17,74732989,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu85Arg/c.254T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),6358,77,6445,"0,0119472459",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"30,4","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_107,17,74732989,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu85Arg/c.254T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),5582,65,5666,"0,0114719379",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"30,25","14,82"
"low bq, low freq, many artifacts",UPN2_111,17,74732989,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu85Arg/c.254T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),3516,54,3590,"0,0150417827",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"30,19","14,57"
"low freq, many artifacts",UPN2_110,17,74733004,A,G,missense_variant(MODERATE|MISSENSE|cTg/cCg|p.Leu80Pro/c.239T>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2341,31,2372,"0,01306914",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,98",Deleterious,0,Damaging,"35,37","35,74"
"low bq, low freq, many artifacts",UPN2_044,17,74733004,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu80Gln/c.239T>A|221|SRSF2|protein_coding|CODING|ENST00000392485|1|T),1660,41,1703,"0,0240751615",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,65",Deleterious,"0,001",Damaging,"34,68","27,54"
"low bq, low freq, many artifacts, many samples",UPN2_050,17,74733004,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu80Gln/c.239T>A|221|SRSF2|protein_coding|CODING|ENST00000392485|1|T),3503,44,3570,"0,01232493",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,65",Deleterious,1,Damaging,"34,52","22,7"
"low freq, many artifacts",UPN2_090,17,74733004,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu80Gln/c.239T>A|221|SRSF2|protein_coding|CODING|ENST00000392485|1|T),1674,20,1700,"0,0117647059",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,65",Deleterious,"0,001",Damaging,"35,51",33
"low bq, low freq, many artifacts, many samples",UPN2_057,17,74733004,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu80Gln/c.239T>A|221|SRSF2|protein_coding|CODING|ENST00000392485|1|T),2847,47,2908,"0,0161623109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,65",Deleterious,1,Damaging,"34,51","22,62"
"low bq, low freq, many artifacts, many samples",UPN2_028,17,74733007,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),3577,38,3647,"0,0104195229",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,34",Deleterious,284,Tolerated,"29,29","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_053,17,74733007,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val79Glu/c.236T>A|221|SRSF2|protein_coding|CODING|ENST00000392485|1|T),4078,48,4156,"0,0115495669",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,93",Neutral,864,Tolerated,"34,26","19,96"
"low bq, low freq, many artifacts",UPN2_057,17,74733007,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val79Glu/c.236T>A|221|SRSF2|protein_coding|CODING|ENST00000392485|1|T),2863,34,2908,"0,0116918845",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,93",Neutral,864,Tolerated,"34,3","19,21"
"low freq, many artifacts",UPN2_044,17,74733008,C,T,missense_variant(MODERATE|MISSENSE|Gtg/Atg|p.Val79Met/c.235G>A|221|SRSF2|protein_coding|CODING|ENST00000392485|1|T),1671,31,1703,"0,0182031709",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,22",Neutral,"0,217",Tolerated,"34,83","30,61"
"low bq, low freq, many artifacts",UPN2_054,17,74733028,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met72Lys/c.215T>A|221|SRSF2|protein_coding|CODING|ENST00000392485|1|T),2190,24,2228,"0,0107719928",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,16",Deleterious,31,Damaging,"34,1","25,21"
many samples,UPN2_002,17,74733032,C,G,missense_variant(MODERATE|MISSENSE|Gct/Cct|p.Ala71Pro/c.211G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1223,35,1260,"0,0277777778",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,9",Deleterious,1,Damaging,"35,49",32
"low freq, many artifacts, many samples",UPN2_029,17,74733032,C,G,missense_variant(MODERATE|MISSENSE|Gct/Cct|p.Ala71Pro/c.211G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2154,29,2191,"0,0132359653",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,9",Deleterious,1,Damaging,"35,41","31,76"
"low freq, many artifacts, many samples",UPN2_049,17,74733032,C,G,missense_variant(MODERATE|MISSENSE|Gct/Cct|p.Ala71Pro/c.211G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),3327,41,3381,"0,0121265898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,9",Deleterious,1,Damaging,"34,81","31,56"
"low freq, many artifacts",UPN2_052,17,74733032,C,G,missense_variant(MODERATE|MISSENSE|Gct/Cct|p.Ala71Pro/c.211G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4300,60,4376,"0,0137111517",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,9",Deleterious,"0,001",Damaging,"34,98","30,53"
"low freq, many artifacts",UPN2_009,17,74733032,C,G,missense_variant(MODERATE|MISSENSE|Gct/Cct|p.Ala71Pro/c.211G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4077,61,4146,"0,0147129764",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,9",Deleterious,"0,001",Damaging,"35,45","31,52"
"low freq, many artifacts, many samples",UPN2_010,17,74733032,C,G,missense_variant(MODERATE|MISSENSE|Gct/Cct|p.Ala71Pro/c.211G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1935,23,1962,"0,0117227319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,9",Deleterious,1,Damaging,"35,5","30,74"
"low freq, many artifacts, many samples",UPN2_056,17,74733032,C,G,missense_variant(MODERATE|MISSENSE|Gct/Cct|p.Ala71Pro/c.211G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1980,22,2012,"0,0109343936",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,9",Deleterious,1,Damaging,"34,87","31,18"
"low freq, many artifacts, many samples",UPN2_057,17,74733032,C,G,missense_variant(MODERATE|MISSENSE|Gct/Cct|p.Ala71Pro/c.211G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2882,32,2939,"0,0108880572",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,9",Deleterious,1,Damaging,"34,86","31,09"
"low freq, many artifacts, many samples",UPN2_058,17,74733032,C,G,missense_variant(MODERATE|MISSENSE|Gct/Cct|p.Ala71Pro/c.211G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),3009,50,3065,"0,0163132137",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,9",Deleterious,1,Damaging,"34,98","30,2"
many samples,UPN2_012,17,74733032,C,G,missense_variant(MODERATE|MISSENSE|Gct/Cct|p.Ala71Pro/c.211G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1263,33,1298,"0,0254237288",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,9",Deleterious,1,Damaging,"35,36",32
"inspected, many artifacts",UPN2_013,17,74733032,C,G,missense_variant(MODERATE|MISSENSE|Gct/Cct|p.Ala71Pro/c.211G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),754,21,776,"0,0270618557",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,9",Deleterious,1,Damaging,"35,44","31,48"
"low freq, many artifacts, many samples",UPN2_006,17,74733034,T,A,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp70Val/c.209A>T|221|SRSF2|protein_coding|CODING|ENST00000392485|1|A),5119,65,5207,"0,0124831957",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,53",Deleterious,26,Damaging,"31,22","29,17"
"low freq, many artifacts, many samples",UPN2_072,17,74733034,T,A,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp70Val/c.209A>T|221|SRSF2|protein_coding|CODING|ENST00000392485|1|A),1733,21,1767,"0,0118845501",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,53",Deleterious,26,Damaging,"31,4","28,05"
"low freq, many artifacts, many samples",UPN2_081,17,74733034,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp70Ala/c.209A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),3003,32,3071,"0,0104200586",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,68",Deleterious,24,Damaging,"31,44","30,88"
"inspected, strandbias",UPN2_084,17,74733034,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp70Ala/c.209A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),800,26,829,"0,0313630881",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,68",Deleterious,24,Damaging,"31,42","30,62"
"low freq, many artifacts",UPN2_044,17,74733041,C,T,missense_variant(MODERATE|MISSENSE|Gct/Act|p.Ala68Thr/c.202G>A|221|SRSF2|protein_coding|CODING|ENST00000392485|1|T),5399,55,5458,"0,0100769513",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,89",Deleterious,1,Damaging,"35,33","35,13"
"low freq, many artifacts",UPN2_072,17,74733041,CG,C,frameshift_variant(HIGH||gac/|p.Asp67fs/c.201delC|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),1743,27,1771,"0,0152456239",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,35",NA
"low freq, many artifacts",UPN2_061,17,74733042,GT,G,frameshift_variant(HIGH||gac/|p.Asp67fs/c.200delA|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1381,31,1434,"0,0216178522",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,54",NA
"low freq, many artifacts",UPN2_040,17,74733043,T,A,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp67Val/c.200A>T|221|SRSF2|protein_coding|CODING|ENST00000392485|1|A),3254,34,3376,"0,01007109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,9",Deleterious,0,Damaging,"35,18","30,79"
"low freq, many artifacts, many samples",UPN2_001,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),5404,92,5537,"0,0166154958",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,03","35,91"
"many samples, low freq, no database",UPN2_014,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),9023,132,9288,"0,0142118863",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,"0,017",Damaging,"35,04","34,88"
"many samples, low freq, no database",UPN2_015,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),13080,317,13546,"0,0234017422",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,"0,017",Damaging,"34,94","35,16"
"many samples, low freq, no database",UPN2_016,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),5726,118,5909,"0,019969538",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,"0,017",Damaging,"35,11","35,47"
"many samples, low freq, no database",UPN2_017,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4372,93,4520,"0,0205752212",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,"0,017",Damaging,"34,97","34,91"
"low freq, many artifacts, many samples",UPN2_018,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),6452,141,6667,"0,0211489426",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,06","34,89"
"many samples, low freq, no database",UPN2_019,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),6956,82,7087,"0,0115704812",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,"0,017",Damaging,"34,99","35,15"
"low freq, many artifacts, many samples",UPN2_020,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),6072,113,6249,"0,0180828933",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,09","35,5"
"low freq, many artifacts, many samples",UPN2_021,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),6496,107,6690,"0,0159940209",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,1","35,13"
"low freq, many artifacts, many samples",UPN2_002,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),7205,103,7381,"0,0139547487",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,03","35,56"
"low freq, many artifacts, many samples",UPN2_003,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1370,23,1402,"0,0164051355",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,35,"34,87"
many samples,UPN2_022,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),8843,215,9152,"0,0234921329",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,11","35,7"
"low freq, many artifacts, many samples",UPN2_023,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),10087,147,10316,"0,0142497092",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,04","35,29"
"many samples, low freq, no database",UPN2_041,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),43487,807,44756,"0,018031102",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,"0,017",Damaging,"34,56","34,95"
"low freq, many artifacts, many samples",UPN2_024,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4549,100,4693,"0,0213083316",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,03",36
"low freq, many artifacts, many samples",UPN2_025,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),11363,251,11749,"0,0213635203",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"34,99","35,22"
"many samples, low freq, no database",UPN2_026,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),10855,195,11163,"0,0174684225",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,"0,017",Damaging,"34,97","34,91"
many samples,UPN2_004,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2261,54,2327,"0,0232058444",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,33","35,72"
"many samples, low freq, no database",UPN2_027,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),10734,250,11114,"0,0224941515",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,"0,017",Damaging,"35,01","35,33"
"low freq, many artifacts, many samples",UPN2_089,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),5502,76,5625,"0,0135111111",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,32","35,13"
"many samples, low freq, no database",UPN2_042,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),20571,422,21296,"0,0198159279",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,"0,017",Damaging,"34,56","34,82"
"many samples, low freq, no database",UPN2_028,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),8237,144,8439,"0,0170636331",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,"0,017",Damaging,"35,17","35,36"
"many samples, low freq, no database",UPN2_043,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),12551,169,12868,"0,0131333541",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,"0,017",Damaging,"34,7","35,47"
"low freq, many artifacts, many samples",UPN2_044,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),5316,65,5459,"0,0119069427",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"34,52","34,74"
"low freq, many artifacts, many samples",UPN2_029,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),9906,185,10229,"0,0180858344",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,2","35,23"
"low freq, many artifacts, many samples",UPN2_030,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),9914,192,10212,"0,0188014101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,13","35,42"
"low freq, many artifacts, many samples",UPN2_031,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),6753,106,6922,"0,0153134932",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,35,"35,16"
"low freq, many artifacts, many samples",UPN2_005,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2374,38,2428,"0,0156507414",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,15","35,21"
"many samples, low freq, no database",UPN2_045,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),18501,413,19128,"0,0215913844",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,"0,017",Damaging,"34,63","34,58"
"low freq, many artifacts, many samples",UPN2_032,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),3656,61,3754,"0,016249334",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,12","35,08"
"low freq, many artifacts, many samples",UPN2_046,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),16004,263,16441,"0,0159965939",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"34,58","35,02"
many samples,UPN2_033,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),7180,166,7441,"0,0223088295",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,11","35,24"
"low freq, many artifacts, many samples",UPN2_034,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2925,55,3013,"0,0182542317",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"34,95","35,6"
"low freq, many artifacts, many samples",UPN2_047,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),23819,297,24438,"0,012153204",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"34,73","34,53"
"many samples, low freq, no database",UPN2_048,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),27360,711,28354,"0,025075827",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,"0,017",Damaging,"34,74","35,13"
"low freq, many artifacts, many samples",UPN2_035,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),8779,154,9045,"0,0170259812",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,12","35,54"
"low freq, many artifacts, many samples",UPN2_036,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),7121,145,7323,"0,0198006282",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,1","34,88"
"low freq, many artifacts, many samples",UPN2_006,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),5092,57,5211,"0,0109383995",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,16","35,26"
"low freq, many artifacts, many samples",UPN2_049,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),14781,276,15279,"0,0180640094",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"34,61","34,65"
many samples,UPN2_050,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),13787,362,14297,"0,0253199972",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"34,54","34,96"
"low freq, many artifacts, many samples",UPN2_037,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),15414,316,15916,"0,0198542347",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,04","35,42"
"low freq, many artifacts, many samples",UPN2_051,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),11153,212,11513,"0,0184139668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"34,56","34,44"
"low freq, many artifacts, many samples",UPN2_052,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),16923,286,17443,"0,0163962621",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"34,45","34,67"
"low freq, many artifacts, many samples",UPN2_038,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),16353,304,16820,"0,0180737218",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,35,"35,26"
"many samples, low freq, no database",UPN2_039,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),5523,164,5727,"0,0286362843",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,"0,017",Damaging,"35,1","35,46"
"many samples, low freq, no database",UPN2_053,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),15188,232,15631,"0,0148423006",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,"0,017",Damaging,"34,55","35,38"
"many samples, low freq, no database",UPN2_054,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),9960,140,10257,"0,0136492152",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,"0,017",Damaging,"34,68","35,41"
"many samples, low freq, no database",UPN2_007,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),16420,310,16861,"0,0183856236",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,"0,017",Damaging,"35,12","35,5"
"many samples, low freq, no database",UPN2_008,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),25075,512,25846,"0,0198096417",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,"0,017",Damaging,"35,05","35,39"
"many samples, low freq, no database",UPN2_009,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),18724,332,19255,"0,0172422747",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,"0,017",Damaging,"35,05","35,58"
"many samples, low freq, no database",UPN2_010,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),11965,194,12335,"0,0157276044",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,"0,017",Damaging,"35,17","35,08"
"low freq, many artifacts, many samples",UPN2_011,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),15505,194,15892,"0,0122073999",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,13","35,44"
"low freq, many artifacts, many samples",UPN2_055,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),18141,342,18725,"0,0182643525",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"34,48","34,85"
"low freq, many artifacts, many samples",UPN2_056,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),8999,144,9268,"0,0155373328",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"34,67","34,85"
"low freq, many artifacts, many samples",UPN2_090,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),6142,65,6262,"0,0103800703",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,23","34,97"
"low freq, many artifacts, many samples",UPN2_057,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),13521,232,13887,"0,0167062721",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"34,79","34,46"
"many samples, low freq, no database",UPN2_058,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),13140,319,13597,"0,0234610576",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,"0,017",Damaging,"34,79","34,88"
many samples,UPN2_012,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),7228,176,7469,"0,0235640648",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,17","35,49"
"low freq, many artifacts, many samples",UPN2_040,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),3254,73,3376,"0,0216232227",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,18","35,44"
many samples,UPN2_013,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4415,101,4569,"0,0221054935",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,14","35,52"
"low freq, many artifacts, many samples",UPN2_091,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),6459,146,6676,"0,0218693829",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,26","35,41"
"low freq, many artifacts, many samples",UPN2_092,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),3278,60,3371,"0,0177988727",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,35","35,2"
many samples,UPN2_062,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2011,57,2086,"0,027325024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"34,42","35,09"
many samples,UPN2_063,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),858,24,885,"0,0271186441",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"34,53","35,08"
many samples,UPN2_065,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),810,20,832,"0,0240384615",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,34",36
many samples,UPN2_071,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2205,62,2285,"0,0271334792",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"34,96","35,69"
"low freq, many artifacts, many samples",UPN2_075,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1474,28,1504,"0,0186170213",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"34,7","34,43"
many samples,UPN2_076,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),905,23,940,"0,0244680851",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,14","35,04"
"low freq, many artifacts, many samples",UPN2_077,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),992,21,1022,"0,0205479452",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,05","34,76"
many samples,UPN2_079,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),586,20,607,"0,0329489292",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,03","34,7"
"many samples, low freq, no database",UPN2_080,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1076,36,1131,"0,0318302387",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,"0,017",Damaging,"34,89",36
"low freq, many artifacts, many samples",UPN2_081,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),3014,40,3075,"0,0130081301",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"34,7","34,7"
many samples,UPN2_085,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),437,34,475,"0,0715789474",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"34,76","35,88"
"low freq, many artifacts, many samples",UPN2_094,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),7359,113,7536,"0,0149946921",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,35","35,04"
"low freq, many artifacts, many samples",UPN2_095,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),6685,132,6877,"0,0191944162",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,35","34,93"
"low freq, many artifacts, many samples",UPN2_096,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),6750,131,6928,"0,018908776",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,39","34,89"
"low freq, many artifacts, many samples",UPN2_097,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),7862,116,8043,"0,0144224792",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,33","35,6"
"low freq, many artifacts, many samples",UPN2_098,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),6605,86,6738,"0,0127634313",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,39","34,74"
"low freq, many artifacts, many samples",UPN2_099,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),3217,54,3301,"0,0163586792",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,28","35,65"
"low freq, many artifacts, many samples",UPN2_100,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4974,103,5127,"0,0200897211",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,33","34,85"
"low freq, many artifacts, many samples",UPN2_101,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),5302,103,5440,"0,0189338235",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,36","35,5"
"low freq, many artifacts, many samples",UPN2_102,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),5700,87,5848,"0,014876881",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,29","35,95"
"many samples, low freq, no database",UPN2_103,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4872,65,4971,"0,0130758399",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,"0,017",Damaging,"35,39","35,54"
"low freq, many artifacts, many samples",UPN2_104,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),6535,107,6687,"0,0160011964",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,4","35,43"
"many samples, low freq, no database",UPN2_105,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),5048,82,5185,"0,0158148505",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,"0,017",Damaging,"35,32","35,44"
"many samples, low freq, no database",UPN2_106,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),10308,235,10628,"0,0221114038",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,"0,017",Damaging,"35,22","35,4"
"many samples, low freq, no database",UPN2_107,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),10376,147,10630,"0,0138287865",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,"0,017",Damaging,"35,32","35,54"
"many samples, low freq, no database",UPN2_108,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),8841,175,9098,"0,0192349967",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,"0,017",Damaging,"35,34","35,01"
"low freq, many artifacts, many samples",UPN2_109,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),7773,131,7969,"0,0164387",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,33","35,28"
"low freq, many artifacts, many samples",UPN2_110,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),8595,136,8804,"0,0154475239",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,37","35,21"
"low freq, many artifacts",UPN2_111,17,74733043,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp67Ala/c.200A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),6451,118,6628,"0,0178032589",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,91",Deleterious,17,Damaging,"35,24","35,12"
"low freq, many artifacts",UPN2_072,17,74733048,C,G,missense_variant(MODERATE|MISSENSE|aaG/aaC|p.Lys65Asn/c.195G>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1741,20,1771,"0,0112930548",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,89",Deleterious,"0,08",Tolerated,"35,26","33,8"
"low freq, many artifacts",UPN2_083,17,74733048,CT,C,frameshift_variant(HIGH||aag/|p.Lys65fs/c.194delA|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),985,20,1011,"0,0197823937",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,13",NA
"low freq, many artifacts",UPN2_071,17,74733050,TG,T,frameshift_variant(HIGH||gac/|p.Asp64fs/c.192delC|221|SRSF2|protein_coding|CODING|ENST00000392485|1|T),2257,25,2286,"0,010936133",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,21",NA
"low freq, many artifacts",UPN2_078,17,74733051,GT,G,frameshift_variant(HIGH||gac/|p.Asp64fs/c.191delA|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1323,24,1350,"0,0177777778",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,13",NA
"low freq, many artifacts",UPN2_093,17,74733055,T,C,missense_variant(MODERATE|MISSENSE|cAc/cGc|p.His63Arg/c.188A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),3461,37,3543,"0,0104431273",0,0,0,0,0,0,0,1,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,29",Deleterious,67,Tolerated,"35,39","35,89"
many samples,UPN2_063,17,74733079,CG,C,frameshift_variant(HIGH||cgc/|p.Arg55fs/c.163delC|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),856,25,884,"0,028280543",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,35,NA
"low freq, many artifacts, many samples",UPN2_081,17,74733079,CG,C,frameshift_variant(HIGH||cgc/|p.Arg55fs/c.163delC|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),3021,40,3071,"0,0130250733",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,96",NA
"many samples, lower bq, no database",UPN2_001,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),5288,224,5530,"0,0405063291",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,54","31,77"
"many samples, lower bq, no database",UPN2_014,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),8845,369,9255,"0,0398703404",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,35","31,77"
"many samples, lower bq, no database",UPN2_015,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),12984,462,13509,"0,0341994226",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,32","31,83"
"many samples, lower bq, no database",UPN2_016,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),5618,258,5898,"0,0437436419",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,3","32,12"
"many samples, lower bq, no database",UPN2_017,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),4284,187,4504,"0,0415186501",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,3","31,92"
"many samples, lower bq, no database",UPN2_018,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),6313,290,6635,"0,0437076112",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,31","31,89"
"many samples, lower bq, no database",UPN2_019,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),6719,314,7067,"0,0444318664",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,28","31,82"
"many samples, lower bq, no database",UPN2_020,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),5970,245,6234,"0,0393006096",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,51","32,12"
"many samples, lower bq, no database",UPN2_021,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),6347,283,6661,"0,0424861132",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,38","31,82"
"many samples, lower bq, no database",UPN2_002,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),7094,248,7360,"0,0336956522",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,58","31,8"
"many samples, lower bq, no database",UPN2_003,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),1355,37,1398,"0,0264663805",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,48","32,11"
"many samples, lower bq, no database",UPN2_022,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),8722,367,9120,"0,0402412281",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,41","31,78"
"many samples, lower bq, no database",UPN2_023,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),9817,428,10267,"0,0416869582",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,41",32
"many samples, lower bq, no database",UPN2_041,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),43664,834,44684,"0,0186643989",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,13","31,89"
"many samples, lower bq, no database",UPN2_024,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),4512,145,4675,"0,0310160428",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,36","31,89"
"many samples, lower bq, no database",UPN2_025,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),11085,572,11704,"0,0488721805",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,22","31,75"
"many samples, lower bq, no database",UPN2_026,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),10578,481,11094,"0,0433567694",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,28","31,89"
"many samples, lower bq, no database",UPN2_004,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),2287,31,2327,"0,0133218737",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,84","32,16"
"many samples, lower bq, no database",UPN2_027,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),10593,442,11081,"0,0398880967",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,4","31,85"
"many samples, lower bq, no database",UPN2_089,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),5504,95,5609,"0,0169370654",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,36","31,75"
"many samples, lower bq, no database",UPN2_042,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),20651,478,21247,"0,0224972937",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,14","31,95"
"many samples, lower bq, no database",UPN2_028,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),8023,360,8406,"0,0428265525",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,36","31,81"
"many samples, lower bq, no database",UPN2_043,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),12488,276,12815,"0,021537261",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,26","31,86"
"many samples, lower bq, no database",UPN2_044,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),5275,134,5428,"0,0246868091",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,06","31,44"
"many samples, lower bq, no database",UPN2_029,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),9857,321,10216,"0,0314212999",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,66","32,02"
"many samples, lower bq, no database",UPN2_030,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),9731,419,10180,"0,0411591356",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,35","31,9"
"many samples, lower bq, no database",UPN2_031,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),6573,303,6901,"0,0439066802",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,26","31,92"
"many samples, lower bq, no database",UPN2_005,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),2332,86,2424,"0,0354785479",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,65","31,72"
"many samples, lower bq, no database",UPN2_045,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),18710,301,19094,"0,0157641144",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,16","31,64"
"many samples, lower bq, no database",UPN2_032,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),3585,133,3732,"0,0356377278",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,33","31,95"
"many samples, lower bq, no database",UPN2_046,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),15879,436,16389,"0,0266032095",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,23","31,98"
"many samples, lower bq, no database",UPN2_033,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),7073,317,7415,"0,04275118",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,34","31,56"
"many samples, lower bq, no database",UPN2_034,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),2897,95,3006,"0,0316034597",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,33","31,98"
"many samples, lower bq, no database",UPN2_047,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),23799,467,24377,"0,0191574025",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,26","32,02"
"many samples, lower bq, no database",UPN2_048,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),27511,638,28242,"0,0225904681",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,32","32,02"
"many samples, lower bq, no database",UPN2_035,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),8559,381,8980,"0,0424276169",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,58","31,63"
"many samples, lower bq, no database",UPN2_036,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),7016,266,7314,"0,0363686081",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,49","32,08"
"many samples, lower bq, no database",UPN2_006,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),5031,163,5211,"0,0312799846",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,64","32,06"
"many samples, lower bq, no database",UPN2_049,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),14921,285,15267,"0,0186677147",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,31","31,87"
"many samples, lower bq, no database",UPN2_050,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),13989,194,14251,"0,0136130798",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,22","31,93"
"many samples, lower bq, no database",UPN2_037,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),15216,611,15878,"0,038480917",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,34","31,98"
"many samples, lower bq, no database",UPN2_051,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),11190,249,11486,"0,0216785652",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,14","31,99"
"many samples, lower bq, no database",UPN2_052,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),17064,254,17395,"0,0146018971",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,18","31,64"
"many samples, lower bq, no database",UPN2_038,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),15983,729,16765,"0,0434834477",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,35","31,91"
"many samples, lower bq, no database",UPN2_039,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),5501,187,5709,"0,0327552987",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,45","31,57"
"many samples, lower bq, no database",UPN2_053,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),15120,395,15580,"0,0253530167",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,22",32
"many samples, lower bq, no database",UPN2_054,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),10008,171,10248,"0,0166861827",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,31","31,65"
"many samples, lower bq, no database",UPN2_007,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),16185,574,16812,"0,0341422793",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,62","31,99"
"many samples, lower bq, no database",UPN2_008,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),24663,1018,25778,"0,0394910389",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,45","31,97"
"many samples, lower bq, no database",UPN2_009,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),18383,762,19196,"0,03969577",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,49","31,88"
"many samples, lower bq, no database",UPN2_010,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),11903,382,12331,"0,0309788338",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,63","31,81"
"many samples, lower bq, no database",UPN2_011,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),15372,464,15885,"0,0292099465",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,66","31,95"
"many samples, lower bq, no database",UPN2_055,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),18156,437,18663,"0,0234153137",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,09","31,99"
"many samples, lower bq, no database",UPN2_056,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),9012,204,9253,"0,0220469037",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,32","32,12"
"many samples, lower bq, no database",UPN2_090,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),6161,79,6250,"0,01264",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,37","32,61"
"many samples, lower bq, no database",UPN2_057,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),13548,253,13869,"0,0182421227",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,35","32,02"
"many samples, lower bq, no database",UPN2_058,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),13116,367,13550,"0,0270848708",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,32","31,94"
"many samples, lower bq, no database",UPN2_012,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),7213,239,7464,"0,0320203644",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,64","31,96"
many samples,UPN2_060,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),768,24,793,"0,0302648172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,27,Damaging,"34,62","31,71"
"many samples, lower bq, no database",UPN2_040,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),3257,118,3384,"0,0348699764",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,48","31,95"
"many samples, lower bq, no database",UPN2_013,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),4398,150,4561,"0,0328875247",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,59","32,14"
"many samples, lower bq, no database",UPN2_091,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),6547,120,6673,"0,0179829162",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,39","32,38"
"many samples, lower bq, no database",UPN2_092,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),3322,42,3370,"0,012462908",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,66","32,55"
"many samples, lower bq, no database",UPN2_093,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),3501,37,3544,"0,0104401806",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,67","31,84"
"many samples, lower bq, no database",UPN2_061,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),1361,51,1420,"0,035915493",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,01","32,31"
"many samples, lower bq, no database",UPN2_062,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),1978,95,2077,"0,0457390467",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,11","31,77"
"many samples, lower bq, no database",UPN2_063,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),843,35,880,"0,0397727273",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,01","31,6"
many samples,UPN2_064,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),402,26,432,"0,0601851852",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,27,Damaging,"33,6",32
many samples,UPN2_065,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),805,21,830,"0,0253012048",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,27,Damaging,"34,66","32,19"
many samples,UPN2_068,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),383,22,406,"0,0541871921",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,27,Damaging,"34,04","31,5"
"many samples, lower bq, no database",UPN2_071,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),2216,59,2282,"0,0258545136",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,42",32
many samples,UPN2_072,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),1710,58,1770,"0,0327683616",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,27,Damaging,"34,39",32
"many samples, lower bq, no database",UPN2_075,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),1431,73,1505,"0,0485049834",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,23","31,86"
"many samples, lower bq, no database",UPN2_076,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),915,25,941,"0,0265674814",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,41","32,32"
"low freq, many artifacts, many samples",UPN2_077,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),998,22,1021,"0,0215475024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,27,Damaging,"34,84","30,36"
"many samples, lower bq, no database",UPN2_078,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),1295,46,1349,"0,0340993328",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,38","31,46"
many samples,UPN2_079,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),582,23,609,"0,0377668309",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,27,Damaging,"34,8","31,39"
"many samples, lower bq, no database",UPN2_080,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),1079,46,1131,"0,0406719717",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,45","31,85"
"many samples, lower bq, no database",UPN2_081,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),2960,92,3064,"0,0300261097",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,22","31,7"
"many samples, lower bq, no database",UPN2_083,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),953,56,1009,"0,0555004955",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,03","32,07"
many samples,UPN2_084,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),798,24,828,"0,0289855072",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,27,Damaging,"34,3",32
"inspected, strandbias",UPN2_087,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),457,25,484,"0,0516528926",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,27,Damaging,34,"31,28"
"many samples, lower bq, no database",UPN2_094,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),7398,110,7524,"0,014619883",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,55","31,71"
"many samples, lower bq, no database",UPN2_095,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),6719,134,6861,"0,0195306807",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,41","32,37"
"many samples, lower bq, no database",UPN2_096,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),6829,73,6910,"0,0105643994",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,49","32,26"
"many samples, lower bq, no database",UPN2_097,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),7895,124,8028,"0,0154459392",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,5","31,97"
"many samples, lower bq, no database",UPN2_098,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),6599,109,6729,"0,0161985436",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,58","31,83"
"many samples, lower bq, no database",UPN2_099,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),3252,37,3296,"0,0112257282",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,62","32,54"
"many samples, lower bq, no database",UPN2_100,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),5043,60,5109,"0,0117439812",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,51","32,2"
"many samples, lower bq, no database",UPN2_101,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),5351,70,5427,"0,0128984706",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,55","32,6"
"many samples, lower bq, no database",UPN2_102,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),5767,66,5843,"0,0112955673",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,61","32,11"
"many samples, lower bq, no database",UPN2_103,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),4892,61,4957,"0,0123058301",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,47","31,9"
"many samples, lower bq, no database",UPN2_104,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),6572,93,6672,"0,0139388489",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,54","32,39"
"many samples, lower bq, no database",UPN2_105,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),5077,93,5173,"0,0179779625",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,53",32
"many samples, lower bq, no database",UPN2_106,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),10436,144,10601,"0,0135836242",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,35","31,97"
"many samples, lower bq, no database",UPN2_107,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),10466,134,10620,"0,0126177024",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,5","31,91"
"many samples, lower bq, no database",UPN2_108,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),8976,102,9086,"0,0112260621",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,47","32,03"
"many samples, lower bq, no database",UPN2_109,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),7853,95,7953,"0,0119451779",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,43","32,23"
"many samples, lower bq, no database",UPN2_111,17,74733085,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu53Gly/c.158A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),6492,107,6604,"0,0162023016",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,"0,027",Damaging,"34,52","32,28"
"low bq, low freq, many artifacts, many samples",UPN2_047,17,74733089,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys52*/c.154A>T|221|SRSF2|protein_coding|CODING|ENST00000392485|1|A),18430,204,18687,"0,01091668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,58","24,38"
"low bq, low freq, many artifacts, many samples",UPN2_058,17,74733089,T,A,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys52*/c.154A>T|221|SRSF2|protein_coding|CODING|ENST00000392485|1|A),10435,106,10578,"0,0100207979",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,51","24,4"
"low freq, many artifacts, many samples",UPN2_044,17,74733097,C,T,missense_variant(MODERATE|MISSENSE|cGc/cAc|p.Arg49His/c.146G>A|221|SRSF2|protein_coding|CODING|ENST00000392485|1|T),3699,48,3751,"0,0127965876",0,0,0,0,0,0,0,1,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,65",Deleterious,294,Tolerated,"35,2","34,02"
"low freq, many artifacts",UPN2_044,17,74733110,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile45Phe/c.133A>T|221|SRSF2|protein_coding|CODING|ENST00000392485|1|A),3689,48,3749,"0,0128034142",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,98",Deleterious,"0,001",Damaging,"34,89","30,44"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,17,74733124,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val40Gly/c.119T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),1837,20,1861,"0,0107469103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,86",Deleterious,0,Damaging,"26,31","15,75"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,17,74733124,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val40Gly/c.119T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),1449,21,1478,"0,0142083897",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,86",Deleterious,0,Damaging,"26,62",14
"low bq, bad alignment, low freq, many artifacts",UPN2_081,17,74733124,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val40Gly/c.119T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),2312,27,2348,"0,0114991482",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,86",Deleterious,0,Damaging,"26,35","14,52"
"low bq, low freq, many artifacts",UPN2_042,17,74733136,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys36Met/c.107A>T|221|SRSF2|protein_coding|CODING|ENST00000392485|1|A),15283,156,15507,"0,0100599729",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,18",Deleterious,1,Damaging,"33,67","21,22"
"low freq, many artifacts",UPN2_006,17,74733138,C,A,missense_variant(MODERATE|MISSENSE|gaG/gaT|p.Glu35Asp/c.105G>T|221|SRSF2|protein_coding|CODING|ENST00000392485|1|A),4442,52,4496,"0,0115658363",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,4",Neutral,"0,229",Tolerated,"35,18","32,17"
"low bq, low freq, many artifacts, many samples",UPN2_014,17,74733145,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val33Gly/c.98T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),6710,102,6843,"0,0149057431",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,63",Deleterious,43,Damaging,"32,99","17,53"
"low bq, low freq, many artifacts, many samples",UPN2_015,17,74733145,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val33Gly/c.98T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),9648,177,9867,"0,0179385832",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,63",Deleterious,43,Damaging,"33,01","17,64"
"low bq, low freq, many artifacts, many samples",UPN2_016,17,74733145,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val33Gly/c.98T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),4149,63,4231,"0,0148900969",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,63",Deleterious,43,Damaging,"33,08","17,22"
"low bq, low freq, many artifacts, many samples",UPN2_017,17,74733145,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val33Gly/c.98T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),3224,58,3294,"0,0176077717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,63",Deleterious,43,Damaging,"33,06","16,05"
"low bq, low freq, many artifacts, many samples",UPN2_018,17,74733145,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val33Gly/c.98T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),4629,75,4717,"0,0158999364",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,63",Deleterious,43,Damaging,33,"16,75"
"low bq, low freq, many artifacts, many samples",UPN2_019,17,74733145,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val33Gly/c.98T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),5014,72,5108,"0,0140955364",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,63",Deleterious,43,Damaging,"33,13","18,53"
"low bq, low freq, many artifacts, many samples",UPN2_020,17,74733145,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val33Gly/c.98T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),4701,70,4787,"0,0146229371",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,63",Deleterious,43,Damaging,"32,89","17,63"
"low bq, low freq, many artifacts, many samples",UPN2_021,17,74733145,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val33Gly/c.98T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),4918,68,4999,"0,0136027205",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,63",Deleterious,43,Damaging,"32,99","18,28"
"low bq, low freq, many artifacts, many samples",UPN2_022,17,74733145,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val33Gly/c.98T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),6729,88,6839,"0,0128673783",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,63",Deleterious,43,Damaging,"33,13","16,31"
"low bq, low freq, many artifacts, many samples",UPN2_023,17,74733145,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val33Gly/c.98T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),7563,105,7696,"0,0136434511",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,63",Deleterious,43,Damaging,"32,86","16,97"
"low bq, low freq, many artifacts, many samples",UPN2_041,17,74733145,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val33Gly/c.98T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),33158,375,33664,"0,0111394962",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,63",Deleterious,43,Damaging,"31,31","16,04"
"low bq, low freq, many artifacts, many samples",UPN2_024,17,74733145,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val33Gly/c.98T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),3452,44,3505,"0,012553495",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,63",Deleterious,43,Damaging,"33,2","16,93"
"low bq, low freq, many artifacts, many samples",UPN2_025,17,74733145,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val33Gly/c.98T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),8010,102,8136,"0,0125368732",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,63",Deleterious,43,Damaging,"32,84","17,7"
"low bq, low freq, many artifacts, many samples",UPN2_026,17,74733145,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val33Gly/c.98T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),7748,114,7912,"0,0144084934",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,63",Deleterious,43,Damaging,"33,12","18,02"
"low bq, low freq, many artifacts, many samples",UPN2_027,17,74733145,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val33Gly/c.98T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),8323,112,8471,"0,0132215795",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,63",Deleterious,43,Damaging,"33,01","16,53"
"low bq, low freq, many artifacts, many samples",UPN2_028,17,74733145,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val33Gly/c.98T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),6083,81,6195,"0,0130750605",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,63",Deleterious,43,Damaging,"33,04","19,52"
"low bq, low freq, many artifacts, many samples",UPN2_029,17,74733145,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val33Gly/c.98T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),8188,111,8331,"0,0133237306",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,63",Deleterious,43,Damaging,"32,95","16,73"
"low bq, low freq, many artifacts, many samples",UPN2_030,17,74733145,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val33Gly/c.98T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),7354,89,7468,"0,0119175147",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,63",Deleterious,43,Damaging,"33,01","17,06"
"low bq, low freq, many artifacts, many samples",UPN2_031,17,74733145,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val33Gly/c.98T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),4827,65,4902,"0,0132598939",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,63",Deleterious,43,Damaging,"32,99","17,46"
"low bq, low freq, many artifacts, many samples",UPN2_046,17,74733145,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val33Gly/c.98T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),12473,139,12661,"0,0109785957",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,63",Deleterious,43,Damaging,"31,37","15,94"
"low bq, low freq, many artifacts, many samples",UPN2_033,17,74733145,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val33Gly/c.98T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),5269,87,5372,"0,0161950856",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,63",Deleterious,43,Damaging,"32,92","18,51"
"low bq, low freq, many artifacts, many samples",UPN2_034,17,74733145,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val33Gly/c.98T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),2269,32,2312,"0,0138408304",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,63",Deleterious,43,Damaging,"32,94","16,41"
"low bq, low freq, many artifacts, many samples",UPN2_035,17,74733145,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val33Gly/c.98T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),6789,95,6911,"0,0137462017",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,63",Deleterious,43,Damaging,"33,04","18,59"
"low bq, low freq, many artifacts, many samples",UPN2_036,17,74733145,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val33Gly/c.98T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),5596,69,5683,"0,0121414746",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,63",Deleterious,43,Damaging,"32,87","18,14"
"low bq, low freq, many artifacts, many samples",UPN2_037,17,74733145,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val33Gly/c.98T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),11631,169,11834,"0,0142808856",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,63",Deleterious,43,Damaging,"33,1","17,29"
"low bq, low freq, many artifacts, many samples",UPN2_038,17,74733145,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val33Gly/c.98T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),12032,150,12223,"0,0122719463",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,63",Deleterious,43,Damaging,"33,12","16,89"
"low bq, low freq, many artifacts, many samples",UPN2_039,17,74733145,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val33Gly/c.98T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),4275,80,4373,"0,0182940773",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,63",Deleterious,43,Damaging,"32,93","17,7"
"low bq, low freq, many artifacts, many samples",UPN2_011,17,74733145,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val33Gly/c.98T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),13875,146,14078,"0,0103707913",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,63",Deleterious,43,Damaging,"32,86","16,75"
"low bq, low freq, many artifacts, many samples",UPN2_055,17,74733145,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val33Gly/c.98T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),13800,155,14000,"0,0110714286",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,63",Deleterious,43,Damaging,"31,41","15,89"
"low bq, low freq, many artifacts, many samples",UPN2_040,17,74733145,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val33Gly/c.98T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),2605,50,2662,"0,01878287",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,63",Deleterious,43,Damaging,"32,93","16,64"
"low bq, low freq, many artifacts, many samples",UPN2_013,17,74733145,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val33Gly/c.98T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),3904,41,3957,"0,0103613849",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,63",Deleterious,43,Damaging,"32,59","15,63"
"low bq, low freq, many artifacts, many samples",UPN2_061,17,74733145,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val33Gly/c.98T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),1059,21,1085,"0,0193548387",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,63",Deleterious,43,Damaging,"29,08","20,43"
"low bq, low freq, many artifacts, many samples",UPN2_071,17,74733145,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val33Gly/c.98T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),1878,30,1915,"0,0156657963",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,63",Deleterious,43,Damaging,"29,01","15,97"
"low bq, low freq, many artifacts, many samples",UPN2_072,17,74733145,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val33Gly/c.98T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),1496,32,1533,"0,0208741031",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,63",Deleterious,43,Damaging,"28,71","18,69"
"low bq, many samples",UPN2_080,17,74733145,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val33Gly/c.98T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),853,21,877,"0,023945268",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,63",Deleterious,43,Damaging,"28,1",21
"low bq, low freq, many artifacts",UPN2_081,17,74733145,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val33Gly/c.98T>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),2373,42,2421,"0,0173482032",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,63",Deleterious,43,Damaging,"28,86","17,29"
"low freq, many artifacts",UPN2_080,17,74733158,T,C,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr29Ala/c.85A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),1657,20,1698,"0,011778563",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,"0,152",Tolerated,"28,84",30
"low bq, low freq, many artifacts, many samples",UPN2_061,17,74733158,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr29Pro/c.85A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2064,22,2100,"0,0104761905",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,54,Tolerated,"29,19","15,41"
"low bq, low freq, many artifacts, many samples",UPN2_062,17,74733158,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr29Pro/c.85A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),3063,34,3118,"0,0109044259",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,54,Tolerated,29,"14,38"
"low bq, low freq, many artifacts, many samples",UPN2_071,17,74733158,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr29Pro/c.85A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),3668,43,3734,"0,0115158007",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,54,Tolerated,"29,2","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_078,17,74733158,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr29Pro/c.85A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2086,33,2134,"0,0154639175",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,54,Tolerated,"28,68",14
"low bq, low freq, many artifacts, many samples",UPN2_081,17,74733158,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr29Pro/c.85A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4606,56,4710,"0,0118895966",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,54,Tolerated,"29,15","14,48"
"low bq, low freq, many artifacts",UPN2_083,17,74733158,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr29Pro/c.85A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1434,27,1475,"0,0183050847",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,54,Tolerated,"28,93",15
"low freq, many artifacts",UPN2_080,17,74733160,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp28Gly/c.83A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),1633,24,1698,"0,0141342756",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,"0,017",Damaging,"29,1","33,38"
"low bq, low freq, many artifacts, many samples",UPN2_060,17,74733160,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp28Ala/c.83A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1246,21,1272,"0,016509434",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,12,Damaging,29,"14,62"
"low bq, low freq, many artifacts, many samples",UPN2_061,17,74733160,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp28Ala/c.83A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2063,37,2101,"0,0176106616",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,12,Damaging,"29,01","15,3"
"low bq, low freq, many artifacts, many samples",UPN2_062,17,74733160,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp28Ala/c.83A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),3044,52,3117,"0,0166827077",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,12,Damaging,"28,73","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_063,17,74733160,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp28Ala/c.83A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1304,28,1333,"0,0210052513",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,12,Damaging,"28,95","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_065,17,74733160,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp28Ala/c.83A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1379,22,1407,"0,0156361052",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,12,Damaging,"29,09","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_071,17,74733160,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp28Ala/c.83A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),3644,67,3732,"0,0179528403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,12,Damaging,"29,02","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_072,17,74733160,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp28Ala/c.83A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2901,51,2960,"0,0172297297",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,12,Damaging,"29,24","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_075,17,74733160,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp28Ala/c.83A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2191,25,2219,"0,0112663362",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,12,Damaging,"29,37","16,56"
"low bq, low freq, many artifacts, many samples",UPN2_076,17,74733160,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp28Ala/c.83A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1545,27,1577,"0,017121116",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,12,Damaging,"28,7","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_077,17,74733160,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp28Ala/c.83A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1743,22,1768,"0,0124434389",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,12,Damaging,"29,1","15,59"
"low bq, low freq, many artifacts, many samples",UPN2_078,17,74733160,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp28Ala/c.83A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2091,38,2134,"0,0178069353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,12,Damaging,"29,04","15,74"
"low bq, low freq, many artifacts, many samples",UPN2_079,17,74733160,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp28Ala/c.83A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),981,22,1015,"0,0216748768",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,12,Damaging,"28,98","15,41"
"low bq, low freq, many artifacts, many samples",UPN2_080,17,74733160,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp28Ala/c.83A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1633,37,1698,"0,0217903416",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,12,Damaging,"29,1","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_081,17,74733160,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp28Ala/c.83A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4602,93,4709,"0,019749416",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,12,Damaging,"29,11","14,56"
"low bq, many samples",UPN2_083,17,74733160,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp28Ala/c.83A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1438,34,1475,"0,0230508475",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,12,Damaging,"28,5","15,15"
low bq,UPN2_084,17,74733160,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp28Ala/c.83A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1287,30,1322,"0,0226928896",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,12,Damaging,"28,41","15,7"
"low bq, low freq, many artifacts, many samples",UPN2_061,17,74733170,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr25Pro/c.73A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2055,31,2103,"0,0147408464",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,74",Deleterious,1,Damaging,"28,14","17,13"
"low bq, low freq, many artifacts, many samples",UPN2_062,17,74733170,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr25Pro/c.73A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),3061,42,3119,"0,0134658544",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,74",Deleterious,1,Damaging,"27,91","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_065,17,74733170,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr25Pro/c.73A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1381,21,1407,"0,0149253731",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,74",Deleterious,1,Damaging,"27,98",14
"low bq, low freq, many artifacts, many samples",UPN2_071,17,74733170,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr25Pro/c.73A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),3659,67,3732,"0,0179528403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,74",Deleterious,1,Damaging,"28,01","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_072,17,74733170,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr25Pro/c.73A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2916,35,2961,"0,011820331",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,74",Deleterious,1,Damaging,"28,01","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_077,17,74733170,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr25Pro/c.73A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1737,23,1767,"0,013016412",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,74",Deleterious,1,Damaging,"28,29","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_078,17,74733170,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr25Pro/c.73A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2090,29,2134,"0,0135895033",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,74",Deleterious,1,Damaging,"28,1",14
"low bq, low freq, many artifacts, many samples",UPN2_079,17,74733170,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr25Pro/c.73A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),986,21,1015,"0,0206896552",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,74",Deleterious,1,Damaging,"27,76","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_080,17,74733170,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr25Pro/c.73A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1666,28,1697,"0,0164997054",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,74",Deleterious,1,Damaging,"27,59","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_081,17,74733170,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr25Pro/c.73A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4616,64,4706,"0,01359966",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,74",Deleterious,1,Damaging,"28,29","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_083,17,74733170,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr25Pro/c.73A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1437,24,1474,"0,0162822252",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,74",Deleterious,1,Damaging,"27,62",16
"low bq, low freq, many artifacts",UPN2_084,17,74733170,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr25Pro/c.73A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1288,23,1321,"0,0174110522",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,74",Deleterious,1,Damaging,"27,02","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_061,17,74733175,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr23Ser/c.68A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2063,36,2101,"0,0171346978",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,44",Deleterious,52,Tolerated,"27,71","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_062,17,74733175,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr23Ser/c.68A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),3051,55,3116,"0,0176508344",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,44",Deleterious,52,Tolerated,"27,72","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_063,17,74733175,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr23Ser/c.68A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1304,25,1331,"0,01878287",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,44",Deleterious,52,Tolerated,"28,1","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_065,17,74733175,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr23Ser/c.68A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1384,20,1407,"0,0142146411",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,44",Deleterious,52,Tolerated,"28,29","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_071,17,74733175,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr23Ser/c.68A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),3662,59,3731,"0,0158134548",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,44",Deleterious,52,Tolerated,"28,03","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_072,17,74733175,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr23Ser/c.68A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2904,42,2960,"0,0141891892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,44",Deleterious,52,Tolerated,"27,95","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_075,17,74733175,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr23Ser/c.68A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2178,35,2219,"0,0157728707",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,44",Deleterious,52,Tolerated,"28,65","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_076,17,74733175,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr23Ser/c.68A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1542,25,1577,"0,0158528852",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,44",Deleterious,52,Tolerated,"27,68","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_077,17,74733175,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr23Ser/c.68A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1738,25,1767,"0,0141482739",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,44",Deleterious,52,Tolerated,"27,81",14
"low bq, low freq, many artifacts, many samples",UPN2_078,17,74733175,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr23Ser/c.68A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2086,45,2134,"0,0210871603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,44",Deleterious,52,Tolerated,"28,15","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_080,17,74733175,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr23Ser/c.68A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1664,31,1697,"0,0182675309",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,44",Deleterious,52,Tolerated,"27,69","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_081,17,74733175,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr23Ser/c.68A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4618,73,4704,"0,0155187075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,44",Deleterious,52,Tolerated,"28,13","14,18"
low bq,UPN2_084,17,74733175,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr23Ser/c.68A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1288,33,1321,"0,0249810749",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,44",Deleterious,52,Tolerated,"27,75","15,33"
"low freq, many artifacts",UPN2_062,17,74733176,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr23Asn/c.67T>A|221|SRSF2|protein_coding|CODING|ENST00000392485|1|T),3072,35,3116,"0,0112323492",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,56",Deleterious,"0,096",Tolerated,"33,75","28,54"
"low freq, many artifacts",UPN2_061,17,74733179,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr22Ala/c.64A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),1977,22,2101,"0,0104712042",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,06",Deleterious,"0,34",Tolerated,"27,97","34,5"
"low bq, low freq, many artifacts, many samples",UPN2_041,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),63515,653,64588,"0,0101102372",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"29,17","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_089,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),7778,79,7891,"0,0100114054",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"30,31","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_044,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),7415,79,7534,"0,0104857977",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"29,03","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_046,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),23869,246,24294,"0,010125957",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"28,93","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_048,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),42794,466,43500,"0,0107126437",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"29,14","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_055,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),26474,277,26954,"0,0102767678",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"29,07","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_090,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),8983,112,9132,"0,0122645642",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"30,36","14,12"
"low bq, low freq, many artifacts, many samples",UPN2_058,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),20820,213,21214,"0,0100405393",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"29,37","14,16"
"low bq, many samples",UPN2_060,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1216,53,1273,"0,0416339356",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"28,58","15,58"
"low bq, low freq, many artifacts, many samples",UPN2_091,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),9603,122,9765,"0,0124935996",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"30,44","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_092,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),5318,57,5401,"0,0105536012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"30,5","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_093,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),5361,59,5440,"0,0108455882",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"30,8",14
"low bq, many samples",UPN2_061,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1977,96,2101,"0,0456925274",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"27,97","15,04"
"low bq, many samples",UPN2_062,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2970,136,3116,"0,0436456996",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"28,23","15,36"
"low bq, many samples",UPN2_063,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1263,64,1330,"0,0481203008",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"28,19","15,53"
"low bq, many samples",UPN2_064,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),547,30,579,"0,0518134715",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"28,06","14,43"
"low bq, many samples",UPN2_065,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1328,73,1407,"0,0518834399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"28,26","15,11"
"low bq, many samples",UPN2_068,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),541,25,566,"0,0441696113",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"28,12","14,56"
"low bq, many samples",UPN2_069,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),784,32,816,"0,0392156863",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"27,83","14,97"
"low bq, many samples",UPN2_070,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),523,20,546,"0,0366300366",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"27,68","15,65"
"low bq, many samples",UPN2_071,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),3570,149,3730,"0,0399463807",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"28,08","15,83"
"low bq, many samples",UPN2_072,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2793,142,2960,"0,047972973",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"28,19","15,04"
"low bq, many samples",UPN2_075,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2141,74,2219,"0,0333483551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"28,3","14,97"
"low bq, many samples",UPN2_076,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1494,73,1577,"0,0462904249",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"27,88","14,97"
"low bq, many samples",UPN2_077,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1672,83,1767,"0,0469722694",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"28,02","14,7"
"low bq, many samples",UPN2_078,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2029,101,2135,"0,0473067916",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"28,42","14,65"
"low bq, many samples",UPN2_079,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),965,48,1015,"0,0472906404",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"28,06","14,92"
"low bq, many samples",UPN2_080,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1622,69,1697,"0,0406599882",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"27,97","14,48"
"low bq, many samples",UPN2_081,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4482,197,4704,"0,0418792517",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"28,15","15,21"
"low bq, many samples",UPN2_082,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),843,28,881,"0,0317820658",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"28,64","14,71"
"low bq, many samples",UPN2_083,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1393,79,1474,"0,0535956581",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"27,65","14,67"
"low bq, many samples",UPN2_084,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1252,63,1321,"0,0476911431",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"27,63","14,67"
"low bq, many samples",UPN2_085,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),676,35,718,"0,0487465181",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"28,53","14,91"
"low bq, many samples",UPN2_087,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),691,30,723,"0,0414937759",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"27,95","16,33"
"low bq, low freq, many artifacts, many samples",UPN2_094,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),11178,136,11345,"0,0119876598",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"30,29","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_095,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),9965,129,10134,"0,0127294257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"30,25","14,05"
"low bq, low freq, many artifacts, many samples",UPN2_096,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),10032,114,10181,"0,0111973284",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"30,36","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_099,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4965,61,5049,"0,0120816003",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"30,43","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_101,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),8276,93,8398,"0,0110740653",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"30,15","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_102,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),8902,103,9032,"0,0114038973",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"30,3","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_103,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),7342,83,7440,"0,011155914",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"30,13","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_106,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),14623,153,14830,"0,0103169252",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"30,52","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_107,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),15410,167,15630,"0,0106845809",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"30,41","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_109,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),11293,127,11465,"0,0110771915",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"30,21","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_110,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),12673,141,12869,"0,0109565623",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"30,36","15,42"
"low bq, low freq, many artifacts",UPN2_111,17,74733179,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr22Pro/c.64A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),9533,125,9689,"0,0129012282",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,24",Deleterious,115,Tolerated,"30,32","15,34"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_001,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4704,57,4780,"0,0119246862",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"19,89","14,58"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_017,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),3291,37,3345,"0,0110612855",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"19,31","14,59"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_002,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),6287,76,6389,"0,0118954453",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"19,01",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_041,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),33112,485,33757,"0,0143673905",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"22,48","14,37"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_024,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),3529,41,3589,"0,0114237949",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"19,99","14,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_004,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2213,23,2247,"0,01023587",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"19,07",14
"low bq, bad alignment, many samples",UPN2_089,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4024,107,4148,"0,0257955641",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"22,45","14,12"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),16320,215,16670,"0,0128974205",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"22,65","14,43"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_028,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),6255,66,6352,"0,0103904282",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"19,63","15,53"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_043,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),10066,123,10236,"0,0120164127",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"22,86","14,5"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_044,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4000,51,4071,"0,0125276345",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"22,42","14,82"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),14536,185,14789,"0,0125092975",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"22,54","14,49"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_032,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2799,29,2837,"0,0102220656",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"20,39","14,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),12684,208,12977,"0,0160283579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"22,36","14,38"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),19773,227,20109,"0,0112884778",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"22,45","14,7"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_048,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),22430,309,22840,"0,0135288967",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"22,43","14,37"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_035,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),7047,72,7163,"0,0100516543",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"20,45","14,86"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_006,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4529,50,4609,"0,0108483402",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"19,54","14,14"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),12635,140,12841,"0,0109025777",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"22,64","14,96"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),11165,148,11372,"0,0130144214",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"22,68","14,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),8517,112,8668,"0,0129210891",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"22,75","14,38"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),13645,179,13925,"0,0128545781",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"22,21","14,2"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_039,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4287,51,4347,"0,0117322291",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"19,51","14,35"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),12015,159,12243,"0,012987013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"22,22","14,47"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),8383,110,8556,"0,012856475",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"22,28","14,86"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_007,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),14448,179,14700,"0,0121768707",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"19,99","14,49"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_008,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),20970,255,21334,"0,0119527515",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"19,26","14,2"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_009,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),15715,165,15943,"0,0103493696",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"19,65","14,13"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_010,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),10726,132,10902,"0,0121078701",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"19,38","14,44"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_011,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),14181,160,14423,"0,0110933925",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"19,77","14,29"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),14122,204,14387,"0,0141794676",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"22,57","14,65"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),7644,91,7782,"0,011693652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"22,6",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_090,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4704,86,4814,"0,0178645617",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"22,68","14,41"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),11386,169,11629,"0,0145326339",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"22,7","14,69"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_058,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),10899,166,11116,"0,0149334293",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"22,69","14,23"
"low bq, bad alignment, many samples",UPN2_060,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),613,57,671,"0,084947839",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"19,56","14,12"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_091,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4999,105,5119,"0,0205118187",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"22,97","15,27"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_092,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2759,57,2824,"0,020184136",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"22,91","14,56"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_093,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2848,56,2909,"0,0192506016",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"23,13","14,38"
"low bq, bad alignment, many samples",UPN2_061,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),995,110,1108,"0,0992779783",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"19,13","14,6"
"low bq, bad alignment, many samples",UPN2_062,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1448,150,1605,"0,0934579439",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"18,73","15,04"
"low bq, bad alignment, many samples",UPN2_063,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),639,68,709,"0,095909732",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"19,05","14,5"
"low bq, bad alignment, many samples",UPN2_064,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),264,28,293,"0,0955631399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"20,06","15,43"
"low bq, bad alignment, many samples",UPN2_065,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),669,64,738,"0,0867208672",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"19,09",14
"low bq, bad alignment, many samples",UPN2_068,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),270,33,303,"0,1089108911",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"19,83","14,42"
"low bq, bad alignment, many samples",UPN2_069,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),379,38,422,"0,0900473934",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"19,14","15,18"
"low bq, bad alignment, many samples",UPN2_070,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),269,32,301,"0,1063122924",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"19,38",14
"low bq, bad alignment, many samples",UPN2_072,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1437,140,1586,"0,0882723834",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"19,1","14,42"
"low bq, bad alignment, many samples",UPN2_073,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),389,39,429,"0,0909090909",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"19,11","14,85"
"low bq, bad alignment, many samples",UPN2_075,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1093,97,1192,"0,0813758389",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"20,18","14,28"
"low bq, bad alignment, many samples",UPN2_076,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),742,90,833,"0,1080432173",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"18,73","14,66"
"low bq, bad alignment, many samples",UPN2_077,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),804,98,905,"0,1082872928",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"18,99","14,68"
"low bq, bad alignment, many samples",UPN2_078,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),988,125,1119,"0,1117068811",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"18,93","15,12"
"low bq, bad alignment, many samples",UPN2_079,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),466,61,528,"0,115530303",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"18,63","14,11"
"low bq, bad alignment, many samples",UPN2_080,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),767,102,873,"0,116838488",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"19,24","14,51"
"low bq, bad alignment, many samples",UPN2_082,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),411,35,447,"0,0782997763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"19,67","14,4"
"low bq, bad alignment, many samples",UPN2_083,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),691,74,779,"0,0949935815",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"19,52","14,68"
"low bq, bad alignment, many samples",UPN2_084,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),618,75,695,"0,1079136691",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"18,85","14,63"
"low bq, bad alignment, many samples",UPN2_085,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),348,37,385,"0,0961038961",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"19,13","14,19"
"low bq, bad alignment, many samples",UPN2_087,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),343,36,380,"0,0947368421",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"19,28","14,56"
"low bq, bad alignment, many samples",UPN2_088,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),263,26,289,"0,0899653979",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"20,7","14,5"
"low bq, bad alignment, many samples",UPN2_094,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),5777,131,5939,"0,0220575855",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"22,62","14,47"
"low bq, bad alignment, many samples",UPN2_095,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),5218,119,5352,"0,0222346786",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"22,5","14,24"
"low bq, bad alignment, many samples",UPN2_096,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),5202,123,5353,"0,0229777695",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"22,67","14,48"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_097,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),6172,119,6304,"0,0188769036",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"22,61","14,18"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_098,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),5375,90,5479,"0,0164263552",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"22,75","14,46"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_099,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2616,47,2671,"0,0175964058",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"22,61",15
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_100,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),3849,66,3934,"0,0167768175",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"22,93","14,21"
"low bq, bad alignment, many samples",UPN2_101,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4265,101,4380,"0,0230593607",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"22,26","14,71"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_102,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4679,86,4783,"0,0179803471",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"22,48","14,47"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_103,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),3808,72,3895,"0,0184852375",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"22,03","14,57"
"low bq, bad alignment, many samples",UPN2_104,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),5083,115,5219,"0,0220348726",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"22,54","14,75"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_105,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),3948,74,4041,"0,0183122989",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"22,41","14,36"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_106,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),7630,149,7799,"0,0191050135",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"22,83","14,19"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_107,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),8010,153,8188,"0,0186858818",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"22,71","14,74"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_108,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),6862,138,7023,"0,0196497223",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"22,96","14,64"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_109,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),5862,131,6007,"0,0218078908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"22,28","14,63"
"low bq, bad alignment, many samples",UPN2_110,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),6553,150,6723,"0,0223114681",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"22,74","14,55"
"low bq, bad alignment",UPN2_111,17,74733184,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn20Thr/c.59A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4967,120,5104,"0,0235109718",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,97",Deleterious,1,Damaging,"22,23","14,81"
"low freq, many artifacts",UPN2_044,17,74733185,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn20Asp/c.58A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),3733,47,3803,"0,0123586642",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,98",Deleterious,"0,004",Damaging,"28,22","33,6"
"low bq, bad alignment, many samples",UPN2_060,17,74733185,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn20His/c.58A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),615,22,641,"0,0343213729",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,98",Deleterious,1,Damaging,"24,69",14
"low bq, bad alignment, many samples",UPN2_061,17,74733185,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn20His/c.58A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1012,43,1058,"0,0406427221",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,98",Deleterious,1,Damaging,"24,13","14,65"
"low bq, bad alignment, many samples",UPN2_062,17,74733185,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn20His/c.58A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1506,57,1569,"0,0363288719",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,98",Deleterious,1,Damaging,"23,68","14,82"
"low bq, bad alignment, many samples",UPN2_063,17,74733185,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn20His/c.58A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),652,21,676,"0,0310650888",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,98",Deleterious,1,Damaging,"24,3","14,33"
"low bq, bad alignment, many samples",UPN2_065,17,74733185,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn20His/c.58A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),681,25,708,"0,0353107345",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,98",Deleterious,1,Damaging,"23,79","14,88"
"low bq, bad alignment, many samples",UPN2_069,17,74733185,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn20His/c.58A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),391,20,414,"0,0483091787",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,98",Deleterious,1,Damaging,"24,32",14
"low bq, bad alignment, many samples",UPN2_072,17,74733185,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn20His/c.58A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1438,52,1493,"0,0348292029",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,98",Deleterious,1,Damaging,"23,89","14,13"
"low bq, bad alignment, many samples",UPN2_075,17,74733185,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn20His/c.58A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1080,28,1115,"0,0251121076",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,98",Deleterious,1,Damaging,"24,71","14,46"
"low bq, bad alignment, many samples",UPN2_076,17,74733185,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn20His/c.58A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),765,31,800,"0,03875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,98",Deleterious,1,Damaging,"23,12","15,55"
"low bq, bad alignment, many samples",UPN2_077,17,74733185,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn20His/c.58A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),844,33,887,"0,0372040586",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,98",Deleterious,1,Damaging,"24,35","15,45"
"low bq, bad alignment, many samples",UPN2_078,17,74733185,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn20His/c.58A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1034,33,1071,"0,0308123249",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,98",Deleterious,1,Damaging,"23,76",14
"low bq, bad alignment, many samples",UPN2_079,17,74733185,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn20His/c.58A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),489,22,513,"0,0428849903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,98",Deleterious,1,Damaging,"23,6","15,18"
"low bq, bad alignment, many samples",UPN2_080,17,74733185,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn20His/c.58A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),813,33,856,"0,0385514019",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,98",Deleterious,1,Damaging,"24,29","15,67"
"low bq, bad alignment, many samples",UPN2_083,17,74733185,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn20His/c.58A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),711,28,742,"0,0377358491",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,98",Deleterious,1,Damaging,"23,84","14,25"
"low bq, bad alignment",UPN2_084,17,74733185,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn20His/c.58A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),625,38,666,"0,0570570571",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,98",Deleterious,1,Damaging,"23,88","15,58"
"low bq, bad alignment, many samples",UPN2_075,17,74733187,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp19Ala/c.56A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1073,37,1114,"0,0332136445",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,96",Deleterious,202,Tolerated,24,"14,57"
"low bq, bad alignment, many samples",UPN2_076,17,74733187,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp19Ala/c.56A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),758,29,793,"0,0365699874",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,96",Deleterious,202,Tolerated,"22,27","14,62"
"low bq, bad alignment, many samples",UPN2_077,17,74733187,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp19Ala/c.56A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),836,52,888,"0,0585585586",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,96",Deleterious,202,Tolerated,"22,8","15,52"
"low bq, bad alignment, many samples",UPN2_078,17,74733187,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp19Ala/c.56A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1025,41,1070,"0,038317757",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,96",Deleterious,202,Tolerated,"22,93","15,8"
"low bq, bad alignment, many samples",UPN2_080,17,74733187,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp19Ala/c.56A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),814,39,854,"0,0456674473",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,96",Deleterious,202,Tolerated,"22,98","15,23"
"low bq, bad alignment, many samples",UPN2_083,17,74733187,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp19Ala/c.56A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),703,38,742,"0,051212938",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,96",Deleterious,202,Tolerated,"22,53","14,68"
"low bq, low freq, many artifacts",UPN2_111,17,74733187,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp19Ala/c.56A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4792,50,4860,"0,0102880658",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,96",Deleterious,202,Tolerated,"28,92","15,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_041,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),31993,440,32622,"0,0134878303",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"25,34","15,06"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_089,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),3869,72,3958,"0,0181910056",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"26,3","14,1"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),15451,196,15743,"0,0124499778",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"25,41","15,12"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_043,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),9563,127,9738,"0,0130416923",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"25,46","14,73"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_044,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),3716,64,3801,"0,0168376743",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"25,11","14,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_005,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2031,26,2061,"0,0126152353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"23,76",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),13832,186,14107,"0,0131849436",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"25,19","14,89"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),12012,187,12258,"0,0152553434",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"25,14","14,27"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),18584,237,18927,"0,0125217943",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"25,2","15,05"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_048,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),21515,339,21973,"0,0154280253",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"25,1","14,53"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),11829,149,12050,"0,0123651452",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"25,5","14,89"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),10630,140,10837,"0,0129187044",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"25,44","14,98"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),8138,111,8291,"0,0133880111",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"25,76","14,55"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),13015,172,13261,"0,0129703642",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"24,97","14,47"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),11402,139,11617,"0,0119652234",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"24,98","14,29"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),7972,107,8132,"0,0131578947",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"25,14","14,85"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_010,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),10342,118,10501,"0,011237025",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"23,57","14,74"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),13368,164,13609,"0,0120508487",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"25,05","14,46"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),7228,92,7361,"0,0124983019",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"25,25","14,43"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_090,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4499,67,4583,"0,014619245",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"26,65","14,19"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),10914,131,11098,"0,0118039286",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"25,5","15,09"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_058,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),10509,147,10729,"0,0137011837",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"25,57","14,31"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_012,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),6161,67,6255,"0,0107114309",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"24,25","15,25"
"low bq, bad alignment, many samples",UPN2_060,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),584,53,641,"0,0826833073",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,21,"15,08"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_091,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4782,90,4902,"0,0183598531",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"26,69","17,04"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_092,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2655,47,2715,"0,0173112339",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"26,56","15,13"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_093,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2677,41,2728,"0,0150293255",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"26,62","14,51"
"low bq, bad alignment, many samples",UPN2_061,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),950,108,1061,"0,1017907634",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"20,86","14,47"
"low bq, bad alignment, many samples",UPN2_062,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1417,137,1571,"0,0872056015",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"20,64","14,24"
"low bq, bad alignment, many samples",UPN2_063,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),617,52,673,"0,0772659733",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"20,63","16,19"
"low bq, bad alignment, many samples",UPN2_065,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),638,67,708,"0,0946327684",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"21,16","15,75"
"low bq, bad alignment, many samples",UPN2_067,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),176,24,200,"0,12",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"21,3","14,29"
"low bq, bad alignment, many samples",UPN2_068,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),256,29,285,"0,101754386",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"19,67","14,69"
"low bq, bad alignment, many samples",UPN2_069,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),374,36,413,"0,0871670702",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"20,37","14,97"
"low bq, bad alignment, many samples",UPN2_070,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),246,30,276,"0,1086956522",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"19,54","15,27"
"low bq, bad alignment, many samples",UPN2_071,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1701,178,1884,"0,0944798301",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"20,87","15,11"
"low bq, bad alignment, many samples",UPN2_072,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1338,152,1494,"0,1017402945",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"20,63","14,88"
"low bq, bad alignment, many samples",UPN2_073,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),367,39,406,"0,0960591133",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"20,59","14,51"
"low bq, bad alignment, many samples",UPN2_075,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),1038,74,1115,"0,066367713",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"21,77","14,72"
"low bq, bad alignment, many samples",UPN2_076,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),726,64,793,"0,0807061791",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"20,77","14,31"
"low bq, bad alignment, many samples",UPN2_077,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),802,84,889,"0,094488189",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"20,44","15,48"
"low bq, bad alignment, many samples",UPN2_078,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),969,96,1072,"0,0895522388",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"21,1","15,27"
"low bq, bad alignment, many samples",UPN2_079,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),468,45,514,"0,0875486381",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"20,72","16,78"
"low bq, bad alignment, many samples",UPN2_080,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),781,70,856,"0,0817757009",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"20,98","15,29"
"low bq, bad alignment, many samples",UPN2_081,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2148,215,2376,"0,0904882155",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"20,89","14,53"
"low bq, bad alignment, many samples",UPN2_082,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),415,28,445,"0,0629213483",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"22,06","14,71"
"low bq, bad alignment, many samples",UPN2_083,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),656,81,743,"0,1090174966",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"19,93","15,38"
"low bq, bad alignment, many samples",UPN2_084,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),595,70,666,"0,1051051051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"20,1","15,16"
"low bq, bad alignment, many samples",UPN2_085,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),320,42,362,"0,1160220994",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"20,65","14,31"
"low bq, bad alignment, many samples",UPN2_087,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),328,34,363,"0,0936639118",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"20,25","15,35"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_094,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),5576,99,5694,"0,0173867229",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"26,3","14,83"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_095,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4962,108,5087,"0,0212305878",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"26,38","14,56"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_096,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),5007,88,5111,"0,0172177656",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"26,45","15,09"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_097,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),5881,101,5994,"0,0168501835",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"26,56","14,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_098,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),5111,85,5217,"0,0162928886",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"26,72","14,42"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_099,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),2496,40,2540,"0,0157480315",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"26,9","14,52"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_100,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),3685,59,3751,"0,0157291389",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"26,82","14,61"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_101,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4140,63,4217,"0,0149395305",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"26,23","14,56"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_102,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4442,81,4534,"0,0178650199",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"26,22","14,63"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_103,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),3664,59,3735,"0,0157965194",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"26,13","14,81"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_104,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4899,74,5001,"0,0147970406",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"26,56","14,36"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_105,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),3794,65,3871,"0,0167915267",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"26,64","15,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_106,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),7297,125,7441,"0,0167988174",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"26,89","14,68"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_107,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),7708,117,7846,"0,0149120571",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"26,79","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_108,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),6603,121,6746,"0,017936555",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"27,02","14,41"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_109,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),5598,118,5752,"0,0205146036",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"26,05","14,69"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_110,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),6321,121,6464,"0,0187190594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"26,45","14,79"
"low bq, bad alignment, low freq, many artifacts",UPN2_111,17,74733203,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr14Pro/c.40A>C|221|SRSF2|protein_coding|CODING|ENST00000392485|1|G),4759,97,4866,"0,0199342376",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,181,Tolerated,"26,37","15,03"
"many samples, homopolymer 6G, ins and del",UPN2_035,17,74733222,A,AG,frameshift_variant(HIGH||cct/ccCt|p.Pro8fs/c.20dupC|221|SRSF2|protein_coding|CODING|ENST00000392485|1|AG),6711,88,6756,"0,0130254589",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,94",NA
"inspected, many samples, homopolymer 6G, ins and del",UPN2_036,17,74733222,A,AG,frameshift_variant(HIGH||cct/ccCt|p.Pro8fs/c.20dupC|221|SRSF2|protein_coding|CODING|ENST00000392485|1|AG),5521,140,5568,"0,0251436782",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,2",NA
"inspected, many samples, homopolymer 6G, ins and del",UPN2_039,17,74733222,A,AG,frameshift_variant(HIGH||cct/ccCt|p.Pro8fs/c.20dupC|221|SRSF2|protein_coding|CODING|ENST00000392485|1|AG),4187,113,4225,"0,0267455621",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,74",NA
"many samples, homopolymer 6G, ins and del",UPN2_040,17,74733222,A,AG,frameshift_variant(HIGH||cct/ccCt|p.Pro8fs/c.20dupC|221|SRSF2|protein_coding|CODING|ENST00000392485|1|AG),2527,43,2546,"0,016889238",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,9",NA
"many samples, homopolymer 6G, ins and del",UPN2_034,17,74733222,AG,A,frameshift_variant(HIGH||cct/|p.Pro7fs/c.20delC|221|SRSF2|protein_coding|CODING|ENST00000392485|1|A),2217,26,2249,"0,0115606936",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,92",NA
"many samples, homopolymer 6G, ins and del",UPN2_093,17,74733222,AG,A,frameshift_variant(HIGH||cct/|p.Pro7fs/c.20delC|221|SRSF2|protein_coding|CODING|ENST00000392485|1|A),2685,39,2731,"0,0142804833",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,08",NA
"many samples, homopolymer 6G, ins and del",UPN2_071,17,74733222,AG,A,frameshift_variant(HIGH||cct/|p.Pro7fs/c.20delC|221|SRSF2|protein_coding|CODING|ENST00000392485|1|A),1861,22,1889,"0,0116463737",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,72",NA
"low freq, many artifacts",UPN2_044,17,74733223,G,A,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro7Leu/c.20C>T|221|SRSF2|protein_coding|CODING|ENST00000392485|1|A),3721,55,3804,"0,0144584648",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,84",Deleterious,"0,091",Tolerated,"34,78","30,73"
"low freq, many artifacts",UPN2_044,17,74733242,T,C,start_lost(HIGH|MISSENSE|Atg/Gtg|p.Met1?/c.1A>G|221|SRSF2|protein_coding|CODING|ENST00000392485|1|C),3751,48,3804,"0,0126182965",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,"0,012",Damaging,"35,68","35,46"
"low freq, many artifacts",UPN2_006,17,74733275,T,A,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-33A>T|221|SRSF2|protein_coding|CODING|ENST00000392485|1|A),4477,54,4544,"0,0118838028",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,26",Neutral,"0,007",Damaging,"35,7","35,37"
"low freq, many artifacts",UPN2_044,17,74733296,T,A,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-54A>T|221|SRSF2|protein_coding|CODING|ENST00000392485|1|A),3706,55,3804,"0,0144584648",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,74","31,8"
"low bq, low freq, many artifacts",UPN2_044,19,33792246,A,C,stop_lost(HIGH|MISSENSE|Tga/Gga|p.Ter359Glyext*?/c.1075T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),5489,59,5578,"0,0105772678",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,37","15,19"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,19,33792269,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val351Gly/c.1052T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),17485,205,17813,"0,0115084489",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,15,Damaging,"24,53","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_059,19,33792269,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val351Gly/c.1052T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2613,40,2673,"0,0149644594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,15,Damaging,"27,13","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_060,19,33792269,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val351Gly/c.1052T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4068,48,4129,"0,0116250908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,15,Damaging,"27,7","16,17"
"low bq, low freq, many artifacts, many samples",UPN2_061,19,33792269,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val351Gly/c.1052T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4780,88,4891,"0,0179922306",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,15,Damaging,"27,08","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_062,19,33792269,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val351Gly/c.1052T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4893,107,5034,"0,0212554629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,15,Damaging,"27,07","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_063,19,33792269,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val351Gly/c.1052T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3260,53,3319,"0,0159686653",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,15,Damaging,"27,23","15,7"
"low bq, low freq, many artifacts, many samples",UPN2_064,19,33792269,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val351Gly/c.1052T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3257,51,3317,"0,0153753392",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,15,Damaging,"27,24","15,39"
"low bq, low freq, many artifacts, many samples",UPN2_065,19,33792269,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val351Gly/c.1052T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3022,45,3077,"0,0146246344",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,15,Damaging,"27,23","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_066,19,33792269,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val351Gly/c.1052T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1495,27,1525,"0,017704918",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,15,Damaging,"27,44","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_067,19,33792269,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val351Gly/c.1052T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2407,44,2465,"0,0178498986",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,15,Damaging,"27,85","14,64"
"low bq, bad alignment, many samples",UPN2_068,19,33792269,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val351Gly/c.1052T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2616,60,2679,"0,0223964166",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,15,Damaging,"26,8","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_069,19,33792269,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val351Gly/c.1052T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4466,87,4580,"0,0189956332",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,15,Damaging,"27,36","15,29"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_070,19,33792269,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val351Gly/c.1052T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2713,42,2766,"0,0151843818",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,15,Damaging,"26,86","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_071,19,33792269,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val351Gly/c.1052T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4841,107,4977,"0,0214988949",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,15,Damaging,"27,41","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_072,19,33792269,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val351Gly/c.1052T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4793,94,4908,"0,0191524042",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,15,Damaging,"27,29","15,52"
"low bq, low freq, many artifacts, many samples",UPN2_073,19,33792269,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val351Gly/c.1052T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4774,102,4897,"0,020829079",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,15,Damaging,"27,46","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_074,19,33792269,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val351Gly/c.1052T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1752,23,1785,"0,0128851541",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,15,Damaging,"27,69","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_075,19,33792269,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val351Gly/c.1052T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),6744,94,6858,"0,01370662",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,15,Damaging,"28,15",15
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,19,33792269,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val351Gly/c.1052T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3612,74,3711,"0,0199407168",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,15,Damaging,"26,57","15,18"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,19,33792269,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val351Gly/c.1052T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4585,91,4700,"0,0193617021",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,15,Damaging,"26,95","15,68"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,19,33792269,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val351Gly/c.1052T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4718,100,4844,"0,0206440958",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,15,Damaging,"26,79","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_079,19,33792269,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val351Gly/c.1052T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3222,50,3279,"0,0152485514",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,15,Damaging,"27,14","15,76"
"low bq, low freq, many artifacts, many samples",UPN2_080,19,33792269,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val351Gly/c.1052T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),6348,104,6474,"0,016064257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,15,Damaging,"27,04","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_081,19,33792269,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val351Gly/c.1052T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),7852,141,8042,"0,017532952",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,15,Damaging,"27,25","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_082,19,33792269,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val351Gly/c.1052T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2989,54,3056,"0,0176701571",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,15,Damaging,"27,57","14,63"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,19,33792269,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val351Gly/c.1052T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4947,86,5053,"0,0170195923",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,15,Damaging,"26,7","15,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,19,33792269,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val351Gly/c.1052T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4075,70,4162,"0,0168188371",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,15,Damaging,"26,64","15,87"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_085,19,33792269,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val351Gly/c.1052T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2664,50,2724,"0,0183553598",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,15,Damaging,"26,78","15,1"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,19,33792269,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val351Gly/c.1052T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1575,26,1607,"0,0161792159",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,15,Damaging,"26,68","15,73"
"low bq, low freq, many artifacts, many samples",UPN2_087,19,33792269,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val351Gly/c.1052T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4647,88,4752,"0,0185185185",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,15,Damaging,"27,47","15,6"
"low bq, low freq, many artifacts",UPN2_088,19,33792269,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val351Gly/c.1052T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3027,50,3081,"0,0162284972",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,49",Deleterious,15,Damaging,"27,96","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_055,19,33792299,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile341Ser/c.1022T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),17414,177,17663,"0,0100209477",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,1,Damaging,"27,51","14,77"
"low bq, bad alignment, many samples",UPN2_059,19,33792299,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile341Ser/c.1022T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2565,96,2672,"0,0359281437",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,1,Damaging,"25,2","14,64"
"low bq, bad alignment, many samples",UPN2_060,19,33792299,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile341Ser/c.1022T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3998,117,4129,"0,0283361589",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,1,Damaging,"25,37","15,04"
"low bq, bad alignment, many samples",UPN2_061,19,33792299,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile341Ser/c.1022T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4718,156,4891,"0,0318953179",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,1,Damaging,"25,1","14,87"
"low bq, bad alignment, many samples",UPN2_062,19,33792299,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile341Ser/c.1022T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4853,164,5032,"0,0325914149",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,1,Damaging,"24,94","14,88"
"low bq, bad alignment, many samples",UPN2_063,19,33792299,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile341Ser/c.1022T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3209,96,3317,"0,0289418149",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,1,Damaging,"25,02","14,84"
"low bq, bad alignment, many samples",UPN2_064,19,33792299,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile341Ser/c.1022T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3194,111,3316,"0,0334740651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,1,Damaging,"25,13","14,61"
"low bq, bad alignment, many samples",UPN2_065,19,33792299,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile341Ser/c.1022T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2971,89,3075,"0,0289430894",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,1,Damaging,"25,18","14,37"
"low bq, bad alignment, many samples",UPN2_066,19,33792299,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile341Ser/c.1022T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1472,49,1525,"0,0321311475",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,1,Damaging,"25,57","14,27"
"low bq, bad alignment, many samples",UPN2_067,19,33792299,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile341Ser/c.1022T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2380,79,2465,"0,0320486815",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,1,Damaging,"25,6","15,29"
"low bq, bad alignment, many samples",UPN2_068,19,33792299,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile341Ser/c.1022T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2587,84,2678,"0,0313666916",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,1,Damaging,"24,55","15,74"
"low bq, bad alignment, many samples",UPN2_069,19,33792299,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile341Ser/c.1022T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4423,143,4579,"0,0312295261",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,1,Damaging,"25,08","14,89"
"low bq, bad alignment, many samples",UPN2_070,19,33792299,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile341Ser/c.1022T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2651,104,2766,"0,0375994215",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,1,Damaging,"24,67","14,64"
"low bq, bad alignment, many samples",UPN2_071,19,33792299,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile341Ser/c.1022T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4804,154,4976,"0,0309485531",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,1,Damaging,"25,18","14,74"
"low bq, bad alignment, many samples",UPN2_072,19,33792299,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile341Ser/c.1022T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4712,181,4907,"0,0368860811",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,1,Damaging,"25,17","15,78"
"low bq, bad alignment, many samples",UPN2_073,19,33792299,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile341Ser/c.1022T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4698,181,4896,"0,0369689542",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,1,Damaging,"25,25","14,83"
"low bq, bad alignment, many samples",UPN2_074,19,33792299,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile341Ser/c.1022T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1721,55,1785,"0,0308123249",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,1,Damaging,"25,68","15,2"
"low bq, bad alignment, many samples",UPN2_075,19,33792299,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile341Ser/c.1022T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),6625,207,6858,"0,030183727",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,1,Damaging,"25,75","14,77"
"low bq, bad alignment, many samples",UPN2_076,19,33792299,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile341Ser/c.1022T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3554,149,3710,"0,0401617251",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,1,Damaging,"24,76","14,69"
"low bq, bad alignment, many samples",UPN2_077,19,33792299,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile341Ser/c.1022T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4512,168,4697,"0,0357675112",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,1,Damaging,"25,03","14,91"
"low bq, bad alignment, many samples",UPN2_078,19,33792299,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile341Ser/c.1022T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4653,177,4841,"0,0365626937",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,1,Damaging,"24,81","14,94"
"low bq, bad alignment, many samples",UPN2_079,19,33792299,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile341Ser/c.1022T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3160,104,3279,"0,0317169869",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,1,Damaging,"25,24","14,63"
"low bq, bad alignment, many samples",UPN2_080,19,33792299,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile341Ser/c.1022T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),6268,185,6473,"0,0285802564",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,1,Damaging,"25,01","14,46"
"low bq, bad alignment, many samples",UPN2_081,19,33792299,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile341Ser/c.1022T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),7752,263,8042,"0,0327033076",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,1,Damaging,"25,02","15,02"
"low bq, bad alignment, many samples",UPN2_082,19,33792299,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile341Ser/c.1022T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2964,83,3055,"0,0271685761",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,1,Damaging,"25,47","14,94"
"low bq, bad alignment, many samples",UPN2_083,19,33792299,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile341Ser/c.1022T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4889,145,5053,"0,0286958243",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,1,Damaging,"24,83","14,85"
"low bq, bad alignment, many samples",UPN2_084,19,33792299,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile341Ser/c.1022T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4014,130,4162,"0,0312349832",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,1,Damaging,"24,89","14,6"
"low bq, bad alignment, many samples",UPN2_085,19,33792299,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile341Ser/c.1022T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2628,89,2724,"0,0326725404",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,1,Damaging,"25,24","15,19"
"low bq, bad alignment, many samples",UPN2_086,19,33792299,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile341Ser/c.1022T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1546,55,1606,"0,0342465753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,1,Damaging,"24,75","14,89"
"low bq, bad alignment, many samples",UPN2_087,19,33792299,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile341Ser/c.1022T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4604,132,4752,"0,0277777778",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,1,Damaging,"25,48","14,81"
"low bq, bad alignment",UPN2_088,19,33792299,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile341Ser/c.1022T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2979,97,3081,"0,0314832846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,1,Damaging,"25,41","14,9"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_015,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),12744,136,12957,"0,0104962568",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"26,29","14,63"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_017,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4089,42,4147,"0,0101278032",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"26,31","14,83"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_019,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),6823,75,6930,"0,0108225108",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"26,14","15,29"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_002,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),7664,85,7770,"0,0109395109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"25,15","14,16"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_003,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1582,27,1620,"0,0166666667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"25,46",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_022,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),8969,108,9126,"0,0118343195",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"26,71","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_041,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),33014,375,33612,"0,0111567297",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"27,65","14,77"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_027,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),11689,121,11861,"0,0102015007",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"26,45","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_043,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),12412,135,12618,"0,0106990014",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"27,85","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_044,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),5486,61,5573,"0,0109456307",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"27,46","14,21"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_029,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),9983,106,10134,"0,0104598382",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"26,57","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_045,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),17462,217,17795,"0,0121944366",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"27,56","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_032,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3710,44,3777,"0,0116494572",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"27,01","15,52"
"low bq, low freq, many artifacts, many samples",UPN2_046,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),16911,195,17223,"0,0113220693",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"27,47","14,55"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_033,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),7722,81,7844,"0,0103263641",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"26,92","14,99"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_034,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2954,34,3003,"0,0113220113",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"26,5","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_047,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),25271,261,25669,"0,0101679068",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"27,61","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_048,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),28128,327,28689,"0,0113980968",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"27,68","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_049,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),15732,173,16016,"0,0108016983",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"27,74","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_050,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),15356,169,15614,"0,0108236198",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"27,81","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_051,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),11740,127,11946,"0,0106311736",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"27,92","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_052,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),13485,152,13721,"0,0110779098",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"27,5","14,22"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_039,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),8453,94,8599,"0,0109315037",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"26,25","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_053,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),16298,176,16571,"0,0106209643",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"27,67","14,44"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_008,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),25126,323,25559,"0,0126374271",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"25,34","14,41"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_009,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),18687,229,19004,"0,0120500947",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"25,55","14,88"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_010,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),12568,150,12769,"0,0117472003",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"25,31","14,79"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_011,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),14837,188,15085,"0,0124627113",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"25,7","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_055,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),17378,199,17658,"0,0112696795",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"27,62","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_057,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),15215,189,15483,"0,0122069366",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"27,74","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_058,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),15071,168,15324,"0,010963195",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"27,84","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_059,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2603,53,2670,"0,0198501873",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"27,82","14,98"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_012,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),8524,116,8678,"0,0133671353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"25,66","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_060,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4039,61,4127,"0,0147807124",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"28,21","14,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_040,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4357,55,4431,"0,012412548",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"26,68","15,58"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_013,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4858,56,4938,"0,0113406237",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"25,87","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_061,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4790,77,4886,"0,0157593123",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"27,46","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_062,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4915,87,5029,"0,017299662",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"27,32","15,37"
"low bq, low freq, many artifacts, many samples",UPN2_063,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3246,56,3316,"0,0168878166",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"27,97","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_064,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3239,60,3311,"0,0181214135",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"27,52","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_065,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2990,62,3074,"0,0201691607",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"27,76","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_066,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1502,20,1524,"0,0131233596",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"28,09",14
"low bq, low freq, many artifacts, many samples",UPN2_067,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2425,32,2463,"0,0129922858",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"28,33","17,03"
"low bq, low freq, many artifacts, many samples",UPN2_068,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2609,50,2677,"0,0186776242",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"27,4","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_069,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4485,75,4579,"0,0163791221",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"27,45","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_070,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2708,47,2765,"0,0169981917",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"27,09","15,51"
"low bq, low freq, many artifacts, many samples",UPN2_071,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4869,81,4969,"0,0163010666",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"27,62","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_072,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4791,94,4904,"0,0191680261",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"27,59","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_073,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4783,85,4888,"0,0173895254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"27,84","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_074,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1750,26,1785,"0,0145658263",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"28,05","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_075,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),6723,95,6855,"0,0138584974",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"28,38","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_076,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3615,75,3708,"0,0202265372",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"27,42","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_077,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4601,75,4694,"0,0159778441",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"27,48","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_078,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4714,96,4839,"0,0198388097",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"27,27","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_079,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3209,53,3278,"0,0161683954",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"27,66","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_080,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),6337,102,6468,"0,0157699443",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"27,53","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_081,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),7867,128,8039,"0,0159223784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"27,57","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_082,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2985,55,3054,"0,0180091683",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,28,"14,45"
"low bq, low freq, many artifacts, many samples",UPN2_083,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4936,87,5048,"0,0172345483",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"27,51","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_084,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4074,64,4156,"0,0153994225",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"27,21","15,69"
"low bq, low freq, many artifacts, many samples",UPN2_085,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2656,48,2721,"0,0176405733",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"27,51","14,65"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1572,25,1605,"0,015576324",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"26,81","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_087,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4655,79,4752,"0,0166245791",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"27,74","15,47"
"low bq, low freq, many artifacts",UPN2_088,19,33792308,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu338Arg/c.1013T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3034,39,3080,"0,0126623377",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"28,27","14,33"
"low freq, many artifacts",UPN2_044,19,33792311,G,A,missense_variant(MODERATE|MISSENSE|aCg/aTg|p.Thr337Met/c.1010C>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),5497,59,5572,"0,0105886576",0,0,0,0,1,0,0,1,2,NO,NO,COSM2751513,large_intestine,2,NO,NO,NO,"1,65E-005",NO,NO,"-5,35",Deleterious,"0,006",Damaging,"33,87","30,98"
"low bq, low freq, many artifacts, many samples",UPN2_015,19,33792312,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr337Pro/c.1009A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),12715,158,12954,"0,0121970048",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,8,Damaging,"29,67",15
"low bq, low freq, many artifacts, many samples",UPN2_006,19,33792312,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr337Pro/c.1009A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4549,47,4617,"0,0101797704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,8,Damaging,"29,76","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_037,19,33792312,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr337Pro/c.1009A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),16858,194,17138,"0,011319874",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,8,Damaging,"29,67","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_039,19,33792312,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr337Pro/c.1009A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),8453,92,8599,"0,0106989185",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,8,Damaging,"29,71","15,74"
"low bq, low freq, many artifacts, many samples",UPN2_008,19,33792312,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr337Pro/c.1009A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),25148,260,25550,"0,0101761252",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,8,Damaging,"29,07","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_009,19,33792312,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr337Pro/c.1009A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),18705,191,19002,"0,0100515735",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,8,Damaging,"29,2","14,64"
"low bq, low freq, many artifacts",UPN2_012,19,33792312,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr337Pro/c.1009A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),8548,93,8678,"0,010716755",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,8,Damaging,"29,33","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_070,19,33792319,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu334Asp/c.1002A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2727,28,2765,"0,0101265823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,92",Deleterious,97,Tolerated,"30,57","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_073,19,33792319,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu334Asp/c.1002A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4814,51,4888,"0,0104337152",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,92",Deleterious,97,Tolerated,"30,67","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_078,19,33792319,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu334Asp/c.1002A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4772,49,4839,"0,0101260591",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,92",Deleterious,97,Tolerated,"30,28","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_001,19,33792327,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser332Arg/c.994A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5728,63,5813,"0,0108377774",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,1",Deleterious,1,Damaging,"29,25","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_015,19,33792327,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser332Arg/c.994A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),12755,139,12969,"0,0107178657",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,1",Deleterious,1,Damaging,"29,72","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_016,19,33792327,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser332Arg/c.994A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5885,65,5977,"0,0108750209",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,1",Deleterious,1,Damaging,"30,19","16,12"
"low bq, low freq, many artifacts, many samples",UPN2_019,19,33792327,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser332Arg/c.994A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),6808,88,6928,"0,0127020785",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,1",Deleterious,1,Damaging,"29,78","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_002,19,33792327,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser332Arg/c.994A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),7643,96,7773,"0,0123504438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,1",Deleterious,1,Damaging,"28,38","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_003,19,33792327,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser332Arg/c.994A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1584,26,1618,"0,0160692213",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,1",Deleterious,1,Damaging,"28,88",14
"low bq, low freq, many artifacts, many samples",UPN2_022,19,33792327,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser332Arg/c.994A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),8987,97,9129,"0,0106254792",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,1",Deleterious,1,Damaging,"29,98","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_024,19,33792327,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser332Arg/c.994A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4176,43,4242,"0,010136728",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,1",Deleterious,1,Damaging,"29,9","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_044,19,33792327,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser332Arg/c.994A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5472,57,5567,"0,0102389078",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,1",Deleterious,1,Damaging,"30,27","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_030,19,33792327,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser332Arg/c.994A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),10059,106,10213,"0,0103789288",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,1",Deleterious,1,Damaging,"29,96","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_045,19,33792327,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser332Arg/c.994A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),17532,181,17822,"0,010155987",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,1",Deleterious,1,Damaging,"30,49","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_046,19,33792327,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser332Arg/c.994A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),16947,189,17227,"0,0109711499",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,1",Deleterious,1,Damaging,"30,49","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_033,19,33792327,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser332Arg/c.994A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),7729,79,7851,"0,0100624124",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,1",Deleterious,1,Damaging,"30,25","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_034,19,33792327,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser332Arg/c.994A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2964,32,3008,"0,0106382979",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,1",Deleterious,1,Damaging,"29,8","15,94"
"low bq, low freq, many artifacts, many samples",UPN2_006,19,33792327,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser332Arg/c.994A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4550,58,4629,"0,012529704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,1",Deleterious,1,Damaging,"28,57","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_037,19,33792327,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser332Arg/c.994A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),16866,187,17139,"0,0109107883",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,1",Deleterious,1,Damaging,"29,72","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_038,19,33792327,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser332Arg/c.994A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),18294,193,18582,"0,0103863954",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,1",Deleterious,1,Damaging,"29,74","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_054,19,33792327,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser332Arg/c.994A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),10644,113,10833,"0,0104310902",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,1",Deleterious,1,Damaging,"30,58","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_007,19,33792327,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser332Arg/c.994A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),15924,180,16165,"0,0111351686",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,1",Deleterious,1,Damaging,"29,21","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_008,19,33792327,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser332Arg/c.994A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),25133,313,25562,"0,0122447383",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,1",Deleterious,1,Damaging,"28,58","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_009,19,33792327,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser332Arg/c.994A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),18682,223,19007,"0,0117325196",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,1",Deleterious,1,Damaging,"28,8","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_010,19,33792327,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser332Arg/c.994A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),12565,156,12762,"0,0122237894",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,1",Deleterious,1,Damaging,"28,71","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_011,19,33792327,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser332Arg/c.994A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),14853,171,15087,"0,0113342613",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,1",Deleterious,1,Damaging,"28,83","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_055,19,33792327,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser332Arg/c.994A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),17374,186,17664,"0,0105298913",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,1",Deleterious,1,Damaging,"30,68","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_012,19,33792327,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser332Arg/c.994A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),8537,94,8675,"0,0108357349",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,1",Deleterious,1,Damaging,"28,84","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_040,19,33792327,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser332Arg/c.994A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4366,49,4430,"0,0110609481",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,1",Deleterious,1,Damaging,"30,08","15,14"
"low bq, low freq, many artifacts",UPN2_013,19,33792327,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser332Arg/c.994A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4841,65,4936,"0,0131685575",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,1",Deleterious,1,Damaging,"28,99","14,34"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_059,19,33792329,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu331Arg/c.992T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2654,50,2721,"0,0183755972",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"25,66","16,68"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_060,19,33792329,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu331Arg/c.992T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4126,68,4208,"0,0161596958",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"26,13","15,51"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,19,33792329,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu331Arg/c.992T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4922,106,5041,"0,0210275739",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"25,6","15,22"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,19,33792329,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu331Arg/c.992T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),5018,103,5144,"0,0200233281",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"25,52","14,44"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,19,33792329,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu331Arg/c.992T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3313,60,3405,"0,0176211454",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"25,71","15,7"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,19,33792329,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu331Arg/c.992T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3309,41,3365,"0,0121842496",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"25,54","15,49"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_065,19,33792329,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu331Arg/c.992T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3049,61,3131,"0,0194825934",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"25,46","14,33"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_066,19,33792329,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu331Arg/c.992T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1544,26,1579,"0,0164661178",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"25,76","15,35"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_067,19,33792329,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu331Arg/c.992T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2446,42,2505,"0,0167664671",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"26,59",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_068,19,33792329,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu331Arg/c.992T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2678,49,2742,"0,0178701678",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"24,91","15,33"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_069,19,33792329,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu331Arg/c.992T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4564,90,4669,"0,0192760762",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"25,48","14,5"
"low bq, bad alignment, many samples",UPN2_070,19,33792329,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu331Arg/c.992T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2753,66,2833,"0,0232968585",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"24,85","14,5"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,19,33792329,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu331Arg/c.992T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4978,82,5080,"0,0161417323",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"25,74","15,33"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,19,33792329,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu331Arg/c.992T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4872,78,4977,"0,0156720916",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"25,36","16,14"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,19,33792329,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu331Arg/c.992T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4889,80,5000,"0,016",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"25,51","14,73"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,19,33792329,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu331Arg/c.992T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1818,20,1848,"0,0108225108",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"25,92","14,9"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_075,19,33792329,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu331Arg/c.992T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),6853,117,6994,"0,0167286245",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"26,38","14,91"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,19,33792329,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu331Arg/c.992T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3760,72,3844,"0,0187304891",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"24,82","14,78"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,19,33792329,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu331Arg/c.992T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4684,81,4792,"0,016903172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"25,54","14,77"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,19,33792329,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu331Arg/c.992T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4808,89,4921,"0,0180857549",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"25,39","14,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_079,19,33792329,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu331Arg/c.992T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3290,55,3368,"0,0163301663",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"25,55","14,89"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,19,33792329,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu331Arg/c.992T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),6452,107,6586,"0,0162465837",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"25,64","14,9"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_081,19,33792329,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu331Arg/c.992T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),8004,142,8203,"0,01731074",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"25,73","15,01"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_082,19,33792329,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu331Arg/c.992T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3030,63,3109,"0,0202637504",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"26,14","15,21"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,19,33792329,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu331Arg/c.992T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),5062,93,5170,"0,0179883946",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"25,36","14,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,19,33792329,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu331Arg/c.992T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4140,68,4226,"0,0160908661",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"24,85","14,9"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_085,19,33792329,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu331Arg/c.992T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2733,61,2812,"0,0216927454",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"25,31","15,13"
"low bq, bad alignment, many samples",UPN2_086,19,33792329,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu331Arg/c.992T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1585,43,1634,"0,0263157895",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"24,88","14,81"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_087,19,33792329,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu331Arg/c.992T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4772,74,4877,"0,0151732623",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"25,45","15,08"
"low bq, bad alignment, low freq, many artifacts",UPN2_088,19,33792329,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu331Arg/c.992T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3053,63,3123,"0,0201729107",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"26,29","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_059,19,33792332,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln330Pro/c.989A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5180,76,5269,"0,0144239894",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,31",Deleterious,13,Damaging,"28,44","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_060,19,33792332,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln330Pro/c.989A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),7982,99,8112,"0,012204142",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,31",Deleterious,13,Damaging,"28,65","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_061,19,33792332,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln330Pro/c.989A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9463,138,9649,"0,0143020002",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,31",Deleterious,13,Damaging,"28,43","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_062,19,33792332,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln330Pro/c.989A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9723,154,9920,"0,0155241935",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,31",Deleterious,13,Damaging,"28,2","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_063,19,33792332,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln330Pro/c.989A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),6412,101,6545,"0,0154316272",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,31",Deleterious,13,Damaging,"28,59","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_064,19,33792332,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln330Pro/c.989A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),6428,71,6528,"0,0108762255",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,31",Deleterious,13,Damaging,"28,38","15,7"
"low bq, low freq, many artifacts, many samples",UPN2_065,19,33792332,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln330Pro/c.989A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5974,74,6066,"0,0121991428",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,31",Deleterious,13,Damaging,"28,69","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_066,19,33792332,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln330Pro/c.989A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2949,38,3007,"0,0126371799",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,31",Deleterious,13,Damaging,"28,67","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_067,19,33792332,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln330Pro/c.989A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4781,56,4859,"0,0115250051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,31",Deleterious,13,Damaging,"28,72","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_068,19,33792332,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln330Pro/c.989A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5201,60,5282,"0,0113593336",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,31",Deleterious,13,Damaging,"28,28","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_069,19,33792332,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln330Pro/c.989A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),8868,131,9018,"0,0145265026",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,31",Deleterious,13,Damaging,"28,64","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_070,19,33792332,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln330Pro/c.989A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5333,73,5437,"0,013426522",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,31",Deleterious,13,Damaging,"28,44","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_071,19,33792332,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln330Pro/c.989A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9634,122,9796,"0,0124540629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,31",Deleterious,13,Damaging,"28,63","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_072,19,33792332,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln330Pro/c.989A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9491,114,9635,"0,011831863",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,31",Deleterious,13,Damaging,"28,63","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_073,19,33792332,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln330Pro/c.989A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9492,121,9658,"0,0125284738",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,31",Deleterious,13,Damaging,"28,7","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_074,19,33792332,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln330Pro/c.989A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3469,40,3520,"0,0113636364",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,31",Deleterious,13,Damaging,"28,75","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_075,19,33792332,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln330Pro/c.989A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),13320,154,13533,"0,0113795906",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,31",Deleterious,13,Damaging,"28,78","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_076,19,33792332,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln330Pro/c.989A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),7188,91,7313,"0,0124435936",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,31",Deleterious,13,Damaging,"28,36","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_077,19,33792332,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln330Pro/c.989A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9124,110,9287,"0,0118445138",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,31",Deleterious,13,Damaging,"28,55","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_078,19,33792332,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln330Pro/c.989A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9402,114,9556,"0,0119296777",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,31",Deleterious,13,Damaging,"28,19","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_079,19,33792332,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln330Pro/c.989A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),6356,81,6468,"0,0125231911",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,31",Deleterious,13,Damaging,"28,64","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_080,19,33792332,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln330Pro/c.989A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),12567,161,12790,"0,0125879593",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,31",Deleterious,13,Damaging,"28,64","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_081,19,33792332,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln330Pro/c.989A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),15616,194,15861,"0,0122312591",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,31",Deleterious,13,Damaging,"28,67","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_082,19,33792332,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln330Pro/c.989A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5946,66,6032,"0,0109416446",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,31",Deleterious,13,Damaging,"28,85","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_083,19,33792332,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln330Pro/c.989A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9772,134,9951,"0,0134659833",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,31",Deleterious,13,Damaging,"28,47","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_084,19,33792332,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln330Pro/c.989A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),8084,108,8216,"0,0131450828",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,31",Deleterious,13,Damaging,"28,35","14,13"
"low bq, low freq, many artifacts, many samples",UPN2_085,19,33792332,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln330Pro/c.989A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5270,56,5368,"0,0104321908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,31",Deleterious,13,Damaging,"28,63","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_086,19,33792332,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln330Pro/c.989A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3097,45,3154,"0,0142675967",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,31",Deleterious,13,Damaging,"28,4","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_087,19,33792332,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln330Pro/c.989A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9214,130,9398,"0,0138327304",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,31",Deleterious,13,Damaging,"28,8","14,19"
"low bq, low freq, many artifacts",UPN2_088,19,33792332,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln330Pro/c.989A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5975,80,6083,"0,0131514056",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,31",Deleterious,13,Damaging,"28,67","14,79"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_059,19,33792334,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu329Asp/c.987A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5111,112,5269,"0,0212564054",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,61",Deleterious,176,Tolerated,"26,53","15,61"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_060,19,33792334,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu329Asp/c.987A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),7920,144,8113,"0,0177492913",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,61",Deleterious,176,Tolerated,"26,69","14,85"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,19,33792334,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu329Asp/c.987A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9439,149,9654,"0,015434017",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,61",Deleterious,176,Tolerated,"26,32","14,05"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,19,33792334,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu329Asp/c.987A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9711,153,9926,"0,0154140641",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,61",Deleterious,176,Tolerated,"26,11","14,55"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,19,33792334,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu329Asp/c.987A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),6419,94,6547,"0,0143577211",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,61",Deleterious,176,Tolerated,"26,54","14,21"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,19,33792334,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu329Asp/c.987A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),6384,92,6529,"0,0140909787",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,61",Deleterious,176,Tolerated,"26,56","14,36"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_065,19,33792334,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu329Asp/c.987A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5949,87,6066,"0,0143422354",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,61",Deleterious,176,Tolerated,"26,72","14,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_066,19,33792334,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu329Asp/c.987A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2938,44,3007,"0,0146325241",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,61",Deleterious,176,Tolerated,"26,64","14,3"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_067,19,33792334,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu329Asp/c.987A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4762,58,4860,"0,0119341564",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,61",Deleterious,176,Tolerated,"26,84","15,12"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_068,19,33792334,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu329Asp/c.987A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5154,93,5283,"0,0176036343",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,61",Deleterious,176,Tolerated,"26,32","14,75"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_069,19,33792334,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu329Asp/c.987A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),8824,133,9021,"0,0147433766",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,61",Deleterious,176,Tolerated,"26,49","14,41"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_070,19,33792334,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu329Asp/c.987A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5317,74,5438,"0,0136079441",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,61",Deleterious,176,Tolerated,"26,4","14,77"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,19,33792334,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu329Asp/c.987A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9609,133,9799,"0,0135728136",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,61",Deleterious,176,Tolerated,"26,66",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,19,33792334,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu329Asp/c.987A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9437,127,9640,"0,0131742739",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,61",Deleterious,176,Tolerated,"26,68","14,26"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,19,33792334,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu329Asp/c.987A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9463,139,9660,"0,014389234",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,61",Deleterious,176,Tolerated,"26,66","14,19"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,19,33792334,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu329Asp/c.987A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3441,50,3520,"0,0142045455",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,61",Deleterious,176,Tolerated,"26,67",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_075,19,33792334,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu329Asp/c.987A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),13225,202,13535,"0,0149242704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,61",Deleterious,176,Tolerated,"26,88","14,38"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,19,33792334,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu329Asp/c.987A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),7167,109,7313,"0,0149049638",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,61",Deleterious,176,Tolerated,"26,42","14,25"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,19,33792334,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu329Asp/c.987A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9090,125,9288,"0,0134582257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,61",Deleterious,176,Tolerated,"26,46","14,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,19,33792334,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu329Asp/c.987A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9313,159,9557,"0,01663702",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,61",Deleterious,176,Tolerated,"26,31","14,57"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_079,19,33792334,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu329Asp/c.987A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),6343,90,6472,"0,0139060569",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,61",Deleterious,176,Tolerated,"26,66","14,42"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,19,33792334,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu329Asp/c.987A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),12543,178,12794,"0,0139127716",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,61",Deleterious,176,Tolerated,"26,58","14,44"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_081,19,33792334,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu329Asp/c.987A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),15521,235,15866,"0,0148115467",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,61",Deleterious,176,Tolerated,"26,7","14,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_082,19,33792334,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu329Asp/c.987A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5922,78,6033,"0,0129288911",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,61",Deleterious,176,Tolerated,"26,81","14,09"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,19,33792334,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu329Asp/c.987A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9764,133,9954,"0,0133614627",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,61",Deleterious,176,Tolerated,"26,31","15,05"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,19,33792334,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu329Asp/c.987A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),8038,118,8220,"0,0143552311",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,61",Deleterious,176,Tolerated,"26,45","14,06"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_085,19,33792334,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu329Asp/c.987A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5251,81,5370,"0,0150837989",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,61",Deleterious,176,Tolerated,"26,44",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,19,33792334,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu329Asp/c.987A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3089,41,3156,"0,012991128",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,61",Deleterious,176,Tolerated,"26,2","15,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_087,19,33792334,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu329Asp/c.987A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9214,127,9403,"0,0135063278",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,61",Deleterious,176,Tolerated,"26,79","14,23"
"low bq, bad alignment, low freq, many artifacts",UPN2_088,19,33792334,T,G,missense_variant(MODERATE|MISSENSE|gaA/gaC|p.Glu329Asp/c.987A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5943,94,6083,"0,0154529015",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,61",Deleterious,176,Tolerated,"26,66","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_059,19,33792335,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu329Ala/c.986A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5165,98,5283,"0,0185500663",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,67",Deleterious,16,Damaging,"27,86","14,07"
"low bq, low freq, many artifacts, many samples",UPN2_060,19,33792335,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu329Ala/c.986A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),7946,158,8135,"0,0194222495",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,67",Deleterious,16,Damaging,"27,94","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_061,19,33792335,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu329Ala/c.986A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9449,184,9679,"0,0190102283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,67",Deleterious,16,Damaging,"27,59","14,11"
"low bq, low freq, many artifacts, many samples",UPN2_062,19,33792335,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu329Ala/c.986A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9703,210,9953,"0,0210991661",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,67",Deleterious,16,Damaging,"27,45","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_063,19,33792335,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu329Ala/c.986A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),6400,132,6565,"0,020106626",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,67",Deleterious,16,Damaging,"27,8","14,2"
"low bq, many samples",UPN2_064,19,33792335,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu329Ala/c.986A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),6360,144,6545,"0,0220015279",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,67",Deleterious,16,Damaging,"27,85","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_065,19,33792335,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu329Ala/c.986A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5956,95,6083,"0,0156172941",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,67",Deleterious,16,Damaging,"28,16",14
"low bq, low freq, many artifacts, many samples",UPN2_066,19,33792335,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu329Ala/c.986A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2933,63,3014,"0,0209024552",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,67",Deleterious,16,Damaging,"28,04","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_067,19,33792335,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu329Ala/c.986A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4752,90,4869,"0,0184842884",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,67",Deleterious,16,Damaging,"28,17","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_068,19,33792335,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu329Ala/c.986A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5180,92,5298,"0,0173650434",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,67",Deleterious,16,Damaging,"27,79","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_069,19,33792335,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu329Ala/c.986A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),8840,161,9036,"0,0178176184",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,67",Deleterious,16,Damaging,"27,86","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_070,19,33792335,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu329Ala/c.986A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5340,102,5457,"0,0186915888",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,67",Deleterious,16,Damaging,"27,71","14,18"
"low bq, low freq, many artifacts, many samples",UPN2_071,19,33792335,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu329Ala/c.986A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9619,170,9823,"0,0173063219",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,67",Deleterious,16,Damaging,"28,07","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_072,19,33792335,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu329Ala/c.986A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9459,153,9664,"0,0158319536",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,67",Deleterious,16,Damaging,"27,9","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_073,19,33792335,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu329Ala/c.986A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9487,163,9683,"0,0168336259",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,67",Deleterious,16,Damaging,"28,07","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_074,19,33792335,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu329Ala/c.986A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3449,72,3531,"0,0203908241",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,67",Deleterious,16,Damaging,"28,05","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_075,19,33792335,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu329Ala/c.986A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),13245,258,13563,"0,0190223402",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,67",Deleterious,16,Damaging,"28,15","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_076,19,33792335,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu329Ala/c.986A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),7164,144,7332,"0,0196399345",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,67",Deleterious,16,Damaging,"27,83","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_077,19,33792335,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu329Ala/c.986A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9069,198,9305,"0,0212788823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,67",Deleterious,16,Damaging,"27,89","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_078,19,33792335,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu329Ala/c.986A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9350,188,9582,"0,0196201211",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,67",Deleterious,16,Damaging,"27,56","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_079,19,33792335,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu329Ala/c.986A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),6351,119,6492,"0,0183302526",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,67",Deleterious,16,Damaging,"27,86","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_080,19,33792335,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu329Ala/c.986A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),12543,207,12814,"0,0161542063",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,67",Deleterious,16,Damaging,"27,94","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_081,19,33792335,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu329Ala/c.986A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),15532,296,15897,"0,0186198654",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,67",Deleterious,16,Damaging,"28,09","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_082,19,33792335,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu329Ala/c.986A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5911,101,6043,"0,0167135529",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,67",Deleterious,16,Damaging,"28,1","14,2"
"low bq, low freq, many artifacts, many samples",UPN2_083,19,33792335,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu329Ala/c.986A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9752,178,9980,"0,0178356713",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,67",Deleterious,16,Damaging,"27,67","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_084,19,33792335,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu329Ala/c.986A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),8055,135,8235,"0,0163934426",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,67",Deleterious,16,Damaging,"27,71","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_085,19,33792335,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu329Ala/c.986A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5285,81,5383,"0,0150473714",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,67",Deleterious,16,Damaging,"27,97","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_086,19,33792335,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu329Ala/c.986A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3088,56,3159,"0,0177271288",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,67",Deleterious,16,Damaging,"27,5","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_087,19,33792335,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu329Ala/c.986A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9206,163,9418,"0,0173072839",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,67",Deleterious,16,Damaging,"28,17","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_088,19,33792335,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu329Ala/c.986A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5948,114,6094,"0,0187069248",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,67",Deleterious,16,Damaging,"27,94","14,57"
"low bq, low freq, many artifacts",UPN2_103,19,33792335,T,G,missense_variant(MODERATE|MISSENSE|gAa/gCa|p.Glu329Ala/c.986A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),12399,132,12564,"0,0105062082",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,67",Deleterious,16,Damaging,"28,96","14,2"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_001,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),11333,118,11519,"0,0102439448",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"26,49","14,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_015,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),25253,269,25736,"0,0104522847",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"26,05","14,81"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_019,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),13515,141,13771,"0,0102389078",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"26,21","14,75"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_002,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),15156,176,15442,"0,0113974874",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"25,73","14,66"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_003,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3164,34,3215,"0,0105754277",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"25,87",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_041,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),65070,890,66672,"0,0133489321",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"26,27","14,62"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_004,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2505,29,2550,"0,011372549",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"25,68","14,24"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),37765,484,38659,"0,0125197237",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"26,26","14,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_043,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),24343,367,24996,"0,0146823492",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"26,51","15,13"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_044,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),10751,176,11062,"0,0159103236",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"26,1","14,19"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_005,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),5076,69,5190,"0,0132947977",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"26,02","14,48"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),34341,505,35250,"0,0143262411",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"26,19","14,61"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_032,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),7370,76,7509,"0,0101211879",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"26,41","14,79"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),33199,529,34148,"0,0154913904",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"26,07","14,75"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_034,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),5856,68,5970,"0,0113902848",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"25,95","14,97"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),49644,746,50920,"0,0146504321",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"26,28","14,82"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_048,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),55614,804,56936,"0,0141211184",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"26,29","14,85"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_006,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),8993,103,9158,"0,0112469972",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"25,8","14,46"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),31003,416,31750,"0,0131023622",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"26,17","14,47"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),30234,394,30983,"0,0127166511",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"26,26","14,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_037,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),33471,341,34081,"0,010005575",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,26,"14,64"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),23089,312,23706,"0,013161225",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"26,33","14,5"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),26490,438,27233,"0,0160834282",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"25,99","15,04"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),32066,479,32836,"0,0145876477",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"26,01","14,59"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),20923,328,21486,"0,0152657544",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"25,91","14,61"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_007,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),31489,329,32085,"0,0102540128",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"26,47","14,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_008,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),49876,596,50821,"0,0117274355",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"26,03","14,57"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_009,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),37041,432,37743,"0,011445831",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"26,14","14,8"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_010,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),24912,301,25409,"0,0118461962",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"25,94","14,55"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),34070,492,34990,"0,0140611603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"26,05","14,99"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),19547,253,20059,"0,0126127923",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"26,19","14,57"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),29837,447,30650,"0,0145840131",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"26,3","14,4"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_058,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),29685,406,30402,"0,0133543846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"26,39","14,93"
"low bq, bad alignment, many samples",UPN2_059,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),5056,199,5286,"0,0376466137",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"24,01","14,68"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_012,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),16901,217,17239,"0,0125877371",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"26,26","14,59"
"low bq, bad alignment, many samples",UPN2_060,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),7798,294,8147,"0,0360869032",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"24,34","14,85"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_040,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),8628,90,8807,"0,0102191439",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"26,34","14,44"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_013,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),9622,104,9808,"0,0106035889",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"26,3","14,47"
"low bq, bad alignment, many samples",UPN2_061,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),9249,370,9689,"0,0381876355",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"23,86","15,25"
"low bq, bad alignment, many samples",UPN2_062,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),9504,377,9963,"0,037840008",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"23,74","14,98"
"low bq, bad alignment, many samples",UPN2_063,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),6244,267,6568,"0,0406516443",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"24,14","14,99"
"low bq, bad alignment, many samples",UPN2_064,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),6225,271,6551,"0,0413677301",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"23,99","14,8"
"low bq, bad alignment, many samples",UPN2_065,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),5817,228,6088,"0,0374507227",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"24,14","15,23"
"low bq, bad alignment, many samples",UPN2_066,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2889,109,3016,"0,0361405836",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"24,24","15,24"
"low bq, bad alignment, many samples",UPN2_067,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4650,181,4877,"0,0371129793",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"24,54","14,76"
"low bq, bad alignment, many samples",UPN2_068,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),5047,227,5307,"0,0427736951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"23,94","14,83"
"low bq, bad alignment, many samples",UPN2_069,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),8625,360,9049,"0,0397834015",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"24,05","14,66"
"low bq, bad alignment, many samples",UPN2_070,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),5192,229,5461,"0,0419337118",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"23,79","14,69"
"low bq, bad alignment, many samples",UPN2_071,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),9342,404,9835,"0,0410777834",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"24,18","15,08"
"low bq, bad alignment, many samples",UPN2_072,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),9220,387,9674,"0,0400041348",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"24,1","15,18"
"low bq, bad alignment, many samples",UPN2_073,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),9258,364,9690,"0,0375644995",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"24,13","15,08"
"low bq, bad alignment, many samples",UPN2_074,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3369,124,3532,"0,0351075878",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"24,41","15,15"
"low bq, bad alignment, many samples",UPN2_075,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),13036,449,13578,"0,0330681986",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"24,55","15,13"
"low bq, bad alignment, many samples",UPN2_076,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),6940,316,7335,"0,0430811179",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"23,85","15,13"
"low bq, bad alignment, many samples",UPN2_077,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),8889,357,9311,"0,0383417463",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"23,96","14,92"
"low bq, bad alignment, many samples",UPN2_078,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),9100,405,9591,"0,0422270879",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"23,75","14,4"
"low bq, bad alignment, many samples",UPN2_079,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),6167,279,6498,"0,0429362881",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"24,04","14,74"
"low bq, bad alignment, many samples",UPN2_080,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),12276,472,12822,"0,0368117298",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"24,07","14,67"
"low bq, bad alignment, many samples",UPN2_081,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),15203,604,15911,"0,0379611589",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"24,21","15,07"
"low bq, bad alignment, many samples",UPN2_082,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),5796,214,6047,"0,0353894493",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"24,52","14,63"
"low bq, bad alignment, many samples",UPN2_083,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),9541,376,9990,"0,0376376376",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"23,83","15,01"
"low bq, bad alignment, many samples",UPN2_084,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),7840,323,8245,"0,0391752577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"23,86","14,98"
"low bq, bad alignment, many samples",UPN2_085,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),5123,212,5384,"0,0393759287",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"24,14","14,88"
"low bq, bad alignment, many samples",UPN2_086,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3011,133,3162,"0,0420619861",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"23,78","14,77"
"low bq, bad alignment, many samples",UPN2_087,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),9021,343,9426,"0,0363887121",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"24,29","14,95"
"low bq, bad alignment",UPN2_088,19,33792338,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val328Gly/c.983T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),5865,206,6102,"0,0337594231",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,82",Deleterious,0,Damaging,"24,58",15
"low bq, low freq, many artifacts",UPN2_086,19,33792339,C,T,missense_variant(MODERATE|MISSENSE|Gtg/Atg|p.Val328Met/c.982G>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),3120,34,3167,"0,010735712",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,0,Damaging,"32,07","27,79"
"low bq, low freq, many artifacts, many samples",UPN2_017,19,33792344,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys326Thr/c.977A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),8102,88,8246,"0,0106718409",0,0,0,0,1,0,0,0,1,NO,0,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-5,02",Deleterious,8,Damaging,"29,13",14
"low bq, low freq, many artifacts, many samples",UPN2_019,19,33792344,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys326Thr/c.977A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),13519,142,13776,"0,0103077816",0,0,0,0,1,0,0,0,1,NO,0,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-5,02",Deleterious,8,Damaging,"28,99",14
"low bq, low freq, many artifacts, many samples",UPN2_003,19,33792344,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys326Thr/c.977A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3154,33,3215,"0,0102643857",0,0,0,0,1,0,0,0,1,NO,0,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-5,02",Deleterious,8,Damaging,"28,66","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_004,19,33792344,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys326Thr/c.977A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2499,27,2553,"0,0105757932",0,0,0,0,1,0,0,0,1,NO,0,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-5,02",Deleterious,8,Damaging,"28,09",14
"low bq, low freq, many artifacts, many samples",UPN2_032,19,33792344,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys326Thr/c.977A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),7373,76,7510,"0,0101198402",0,0,0,0,1,0,0,0,1,NO,0,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-5,02",Deleterious,8,Damaging,"29,27",14
"low bq, low freq, many artifacts, many samples",UPN2_035,19,33792344,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys326Thr/c.977A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),15090,169,15408,"0,0109683281",0,0,0,0,1,0,0,0,1,NO,0,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-5,02",Deleterious,8,Damaging,"29,18","14,08"
"low bq, low freq, many artifacts, many samples",UPN2_037,19,33792344,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys326Thr/c.977A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),33485,357,34092,"0,0104716649",0,0,0,0,1,0,0,0,1,NO,0,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-5,02",Deleterious,8,Damaging,"28,94","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_039,19,33792344,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys326Thr/c.977A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),16807,176,17098,"0,0102936016",0,0,0,0,1,0,0,0,1,NO,0,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-5,02",Deleterious,8,Damaging,"28,87","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_060,19,33792344,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys326Thr/c.977A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),8049,89,8164,"0,0109015189",0,0,0,0,1,0,0,0,1,NO,0,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-5,02",Deleterious,8,Damaging,"27,86","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_040,19,33792344,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys326Thr/c.977A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),8627,98,8813,"0,0111199365",0,0,0,0,1,0,0,0,1,NO,0,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-5,02",Deleterious,8,Damaging,"29,08","14,13"
"low bq, low freq, many artifacts, many samples",UPN2_061,19,33792344,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys326Thr/c.977A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9536,123,9704,"0,0126751855",0,0,0,0,1,0,0,0,1,NO,0,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-5,02",Deleterious,8,Damaging,"27,63","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_062,19,33792344,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys326Thr/c.977A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9785,136,9978,"0,013629986",0,0,0,0,1,0,0,0,1,NO,0,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-5,02",Deleterious,8,Damaging,"27,31","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_063,19,33792344,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys326Thr/c.977A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),6467,77,6581,"0,0117003495",0,0,0,0,1,0,0,0,1,NO,0,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-5,02",Deleterious,8,Damaging,"27,68","15,7"
"low bq, low freq, many artifacts, many samples",UPN2_064,19,33792344,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys326Thr/c.977A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),6466,76,6558,"0,0115888991",0,0,0,0,1,0,0,0,1,NO,0,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-5,02",Deleterious,8,Damaging,"27,65","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_067,19,33792344,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys326Thr/c.977A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4797,63,4881,"0,0129071911",0,0,0,0,1,0,0,0,1,NO,0,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-5,02",Deleterious,8,Damaging,"28,27","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_068,19,33792344,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys326Thr/c.977A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5224,68,5314,"0,0127963869",0,0,0,0,1,0,0,0,1,NO,0,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-5,02",Deleterious,8,Damaging,"27,57",14
"low bq, low freq, many artifacts, many samples",UPN2_069,19,33792344,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys326Thr/c.977A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),8895,127,9064,"0,014011474",0,0,0,0,1,0,0,0,1,NO,0,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-5,02",Deleterious,8,Damaging,"27,8","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_070,19,33792344,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys326Thr/c.977A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5379,77,5473,"0,0140690663",0,0,0,0,1,0,0,0,1,NO,0,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-5,02",Deleterious,8,Damaging,"27,61","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_071,19,33792344,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys326Thr/c.977A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9699,111,9851,"0,0112678916",0,0,0,0,1,0,0,0,1,NO,0,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-5,02",Deleterious,8,Damaging,"27,94","15,52"
"low bq, low freq, many artifacts, many samples",UPN2_072,19,33792344,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys326Thr/c.977A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9519,111,9696,"0,0114480198",0,0,0,0,1,0,0,0,1,NO,0,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-5,02",Deleterious,8,Damaging,"28,03","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_073,19,33792344,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys326Thr/c.977A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9558,111,9708,"0,011433869",0,0,0,0,1,0,0,0,1,NO,0,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-5,02",Deleterious,8,Damaging,"27,93","14,06"
"low bq, low freq, many artifacts, many samples",UPN2_074,19,33792344,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys326Thr/c.977A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3478,45,3540,"0,0127118644",0,0,0,0,1,0,0,0,1,NO,0,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-5,02",Deleterious,8,Damaging,"27,75","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_075,19,33792344,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys326Thr/c.977A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),13363,145,13593,"0,0106672552",0,0,0,0,1,0,0,0,1,NO,0,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-5,02",Deleterious,8,Damaging,"28,31","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_076,19,33792344,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys326Thr/c.977A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),7222,89,7351,"0,0121071963",0,0,0,0,1,0,0,0,1,NO,0,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-5,02",Deleterious,8,Damaging,"27,65","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_077,19,33792344,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys326Thr/c.977A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9164,102,9324,"0,0109395109",0,0,0,0,1,0,0,0,1,NO,0,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-5,02",Deleterious,8,Damaging,"27,71","14,13"
"low bq, low freq, many artifacts, many samples",UPN2_078,19,33792344,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys326Thr/c.977A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9443,124,9603,"0,0129126315",0,0,0,0,1,0,0,0,1,NO,0,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-5,02",Deleterious,8,Damaging,"27,53","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_079,19,33792344,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys326Thr/c.977A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),6410,67,6508,"0,0102950215",0,0,0,0,1,0,0,0,1,NO,0,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-5,02",Deleterious,8,Damaging,"28,05","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_080,19,33792344,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys326Thr/c.977A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),12623,170,12839,"0,0132409066",0,0,0,0,1,0,0,0,1,NO,0,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-5,02",Deleterious,8,Damaging,"27,84","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_081,19,33792344,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys326Thr/c.977A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),15700,174,15937,"0,0109179896",0,0,0,0,1,0,0,0,1,NO,0,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-5,02",Deleterious,8,Damaging,28,"14,1"
"low bq, low freq, many artifacts, many samples",UPN2_084,19,33792344,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys326Thr/c.977A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),8125,92,8256,"0,0111434109",0,0,0,0,1,0,0,0,1,NO,0,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-5,02",Deleterious,8,Damaging,"27,78","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_085,19,33792344,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys326Thr/c.977A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5296,76,5392,"0,0140949555",0,0,0,0,1,0,0,0,1,NO,0,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-5,02",Deleterious,8,Damaging,"27,75","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_086,19,33792344,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys326Thr/c.977A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3119,37,3170,"0,0116719243",0,0,0,0,1,0,0,0,1,NO,0,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-5,02",Deleterious,8,Damaging,"27,48","15,03"
"low bq, low freq, many artifacts",UPN2_087,19,33792344,T,G,missense_variant(MODERATE|MISSENSE|aAg/aCg|p.Lys326Thr/c.977A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9281,102,9433,"0,0108131029",0,0,0,0,1,0,0,0,1,NO,0,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-5,02",Deleterious,8,Damaging,"28,07","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_059,19,33792345,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys326Gln/c.976A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5212,65,5302,"0,0122595247",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,3",Deleterious,47,Damaging,"28,49","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_060,19,33792345,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys326Gln/c.976A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),8052,83,8165,"0,0101653399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,3",Deleterious,47,Damaging,"28,6","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_062,19,33792345,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys326Gln/c.976A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9795,108,9977,"0,0108248973",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,3",Deleterious,47,Damaging,"28,02","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_068,19,33792345,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys326Gln/c.976A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5229,58,5314,"0,0109145653",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,3",Deleterious,47,Damaging,"28,32","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_070,19,33792345,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys326Gln/c.976A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5398,58,5473,"0,0105974785",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,3",Deleterious,47,Damaging,"28,48","14,34"
"low bq, low freq, many artifacts",UPN2_073,19,33792345,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys326Gln/c.976A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9566,108,9708,"0,0111248455",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,3",Deleterious,47,Damaging,"28,86","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_059,19,33792350,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu324Arg/c.971T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),5196,68,5303,"0,0128229304",0,0,0,0,1,0,0,0,1,NO,NO,COSM4170200,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"28,97","15,41"
"low bq, low freq, many artifacts, many samples",UPN2_060,19,33792350,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu324Arg/c.971T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),8034,94,8167,"0,0115097343",0,0,0,0,1,0,0,0,1,NO,NO,COSM4170200,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"29,01","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_061,19,33792350,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu324Arg/c.971T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),9528,114,9704,"0,0117477329",0,0,0,0,1,0,0,0,1,NO,NO,COSM4170200,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"28,78","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_062,19,33792350,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu324Arg/c.971T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),9791,124,9976,"0,0124298316",0,0,0,0,1,0,0,0,1,NO,NO,COSM4170200,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"28,56","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_064,19,33792350,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu324Arg/c.971T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),6446,78,6559,"0,0118920567",0,0,0,0,1,0,0,0,1,NO,NO,COSM4170200,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"28,83","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_065,19,33792350,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu324Arg/c.971T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),5967,75,6096,"0,0123031496",0,0,0,0,1,0,0,0,1,NO,NO,COSM4170200,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"28,9","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_067,19,33792350,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu324Arg/c.971T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4802,57,4882,"0,0116755428",0,0,0,0,1,0,0,0,1,NO,NO,COSM4170200,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"29,43","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_068,19,33792350,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu324Arg/c.971T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),5209,65,5314,"0,0122318404",0,0,0,0,1,0,0,0,1,NO,NO,COSM4170200,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"28,64","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_069,19,33792350,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu324Arg/c.971T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),8886,113,9066,"0,0124641518",0,0,0,0,1,0,0,0,1,NO,NO,COSM4170200,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"28,77","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_070,19,33792350,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu324Arg/c.971T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),5358,87,5476,"0,0158875091",0,0,0,0,1,0,0,0,1,NO,NO,COSM4170200,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"28,56","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_071,19,33792350,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu324Arg/c.971T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),9657,123,9853,"0,0124835076",0,0,0,0,1,0,0,0,1,NO,NO,COSM4170200,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"28,92","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_072,19,33792350,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu324Arg/c.971T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),9508,105,9694,"0,0108314421",0,0,0,0,1,0,0,0,1,NO,NO,COSM4170200,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"28,86","14,12"
"low bq, low freq, many artifacts, many samples",UPN2_073,19,33792350,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu324Arg/c.971T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),9511,117,9709,"0,0120506746",0,0,0,0,1,0,0,0,1,NO,NO,COSM4170200,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"28,96","15,51"
"low bq, low freq, many artifacts, many samples",UPN2_074,19,33792350,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu324Arg/c.971T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3477,42,3542,"0,0118577075",0,0,0,0,1,0,0,0,1,NO,NO,COSM4170200,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"28,85","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_075,19,33792350,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu324Arg/c.971T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),13331,169,13597,"0,0124292123",0,0,0,0,1,0,0,0,1,NO,NO,COSM4170200,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"29,22","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_076,19,33792350,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu324Arg/c.971T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),7185,87,7347,"0,011841568",0,0,0,0,1,0,0,0,1,NO,NO,COSM4170200,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"28,67","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_077,19,33792350,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu324Arg/c.971T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),9134,121,9325,"0,0129758713",0,0,0,0,1,0,0,0,1,NO,NO,COSM4170200,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"28,83","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_078,19,33792350,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu324Arg/c.971T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),9426,112,9605,"0,0116605934",0,0,0,0,1,0,0,0,1,NO,NO,COSM4170200,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"28,53","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_079,19,33792350,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu324Arg/c.971T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),6410,69,6507,"0,010603965",0,0,0,0,1,0,0,0,1,NO,NO,COSM4170200,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"28,89","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_080,19,33792350,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu324Arg/c.971T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),12598,138,12841,"0,0107468266",0,0,0,0,1,0,0,0,1,NO,NO,COSM4170200,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"28,94","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_081,19,33792350,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu324Arg/c.971T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),15655,187,15941,"0,0117307572",0,0,0,0,1,0,0,0,1,NO,NO,COSM4170200,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"28,97","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_082,19,33792350,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu324Arg/c.971T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),5959,65,6054,"0,010736703",0,0,0,0,1,0,0,0,1,NO,NO,COSM4170200,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"29,16","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_083,19,33792350,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu324Arg/c.971T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),9829,126,10013,"0,0125836413",0,0,0,0,1,0,0,0,1,NO,NO,COSM4170200,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"28,56","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_084,19,33792350,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu324Arg/c.971T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),8114,103,8260,"0,0124697337",0,0,0,0,1,0,0,0,1,NO,NO,COSM4170200,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"28,52","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_085,19,33792350,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu324Arg/c.971T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),5293,64,5392,"0,0118694362",0,0,0,0,1,0,0,0,1,NO,NO,COSM4170200,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"28,83",14
"low bq, low freq, many artifacts, many samples",UPN2_086,19,33792350,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu324Arg/c.971T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3100,46,3169,"0,0145156201",0,0,0,0,1,0,0,0,1,NO,NO,COSM4170200,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"28,53","14,28"
"low bq, low freq, many artifacts",UPN2_087,19,33792350,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu324Arg/c.971T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),9242,116,9436,"0,0122933446",0,0,0,0,1,0,0,0,1,NO,NO,COSM4170200,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"29,15","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_001,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),11343,168,11540,"0,0145580589",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"27,07","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_015,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),25297,300,25674,"0,0116849731",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"27,39","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_016,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),11682,146,11868,"0,0123019885",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"28,05","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_017,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),8116,95,8238,"0,0115319252",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"27,56","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_020,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),11543,118,11698,"0,0100871944",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"27,92","14,95"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_002,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),15147,208,15418,"0,0134907251",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"26,24","14,84"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_003,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3151,54,3210,"0,0168224299",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"26,46","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_022,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),17825,210,18100,"0,0116022099",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"27,57","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_041,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),65547,828,66654,"0,0124223602",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"27,35","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_024,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),8273,86,8392,"0,0102478551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"27,83","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_026,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),20643,237,20962,"0,0113061731",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"27,47","14,7"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_004,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2526,39,2571,"0,0151691949",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"26,54",14
"low bq, low freq, many artifacts, many samples",UPN2_027,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),23192,257,23525,"0,0109245484",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"27,47","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_042,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),37987,471,38656,"0,0121843957",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"27,34","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_028,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),16217,189,16485,"0,0114649682",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"27,22","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_043,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),24572,315,25011,"0,0125944584",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"27,43","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_044,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),10847,152,11060,"0,0137432188",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"27,18","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_029,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),19803,209,20087,"0,0104047394",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"27,65","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_030,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),19939,223,20255,"0,0110096273",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"27,63","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_031,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),13321,157,13524,"0,0116089914",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"27,77","14,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_005,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5089,70,5186,"0,0134978789",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"26,93","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_045,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),34630,478,35306,"0,0135387753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"27,25","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_032,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),7387,82,7494,"0,010942087",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"27,75","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_046,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),33566,457,34173,"0,0133731308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"27,17","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_034,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5858,61,5955,"0,0102434929",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"27,7","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_047,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),50085,632,50923,"0,0124108949",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"27,35","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_048,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),55974,677,56929,"0,0118920058",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"27,32","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_036,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),29413,330,29867,"0,0110489838",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"27,79","14,42"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_006,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),8986,120,9159,"0,013101867",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"26,6","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_049,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),31208,390,31762,"0,0122788238",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"27,18","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_050,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),30450,387,30988,"0,0124887053",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"27,25","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_037,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),33477,409,34004,"0,0120279967",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"27,44","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_051,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),23335,258,23700,"0,0108860759",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"27,53","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_052,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),26781,330,27213,"0,0121265572",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"27,12","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_038,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),36269,413,36815,"0,0112182534",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"27,59","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_039,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),16787,216,17062,"0,0126597116",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"27,4","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_053,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),32326,423,32853,"0,0128755365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"27,11","14,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),21085,304,21485,"0,0141494066",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"26,99","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_007,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),31496,432,32047,"0,013480201",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"27,19","14,68"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_008,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),49867,721,50744,"0,0142085764",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"26,76","14,52"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_009,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),37100,463,37713,"0,0122769337",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"26,83","14,51"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_010,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),24940,352,25376,"0,0138713745",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"26,59","14,75"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_011,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),29406,376,29909,"0,0125714668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"26,98","15,55"
"low bq, low freq, many artifacts, many samples",UPN2_055,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),34356,430,34998,"0,0122864164",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"27,15","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_056,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),19718,239,20051,"0,011919605",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"27,26","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_057,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),30160,395,30653,"0,0128861775",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"27,42","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_058,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),29885,374,30417,"0,0122957557",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"27,47","14,64"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_059,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5176,99,5285,"0,0187322611",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"24,7","14,31"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_012,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),16898,234,17218,"0,0135904286",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"26,9","15,28"
"low bq, bad alignment, many samples",UPN2_060,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),7906,191,8143,"0,0234557288",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"24,81","14,18"
"low bq, low freq, many artifacts, many samples",UPN2_040,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),8649,100,8790,"0,0113765643",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"27,81","14,8"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_013,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9627,134,9797,"0,0136776564",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"26,94","14,26"
"low bq, bad alignment, many samples",UPN2_061,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9423,214,9667,"0,0221371677",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"24,36","14,64"
"low bq, bad alignment, many samples",UPN2_062,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9654,249,9932,"0,0250704793",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"24,28","14,56"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),6404,137,6559,"0,0208873304",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"24,56","15,49"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),6390,121,6541,"0,0184987005",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"24,59","14,49"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_065,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5945,112,6076,"0,0184331797",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"24,84","14,29"
"low bq, bad alignment, many samples",UPN2_066,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2929,68,3013,"0,0225688682",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"24,9","14,57"
"low bq, bad alignment, many samples",UPN2_067,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4732,107,4863,"0,0220028789",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"25,01","14,19"
"low bq, bad alignment, many samples",UPN2_068,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5144,131,5285,"0,0247871334",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"24,65","14,69"
"low bq, bad alignment, many samples",UPN2_069,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),8770,228,9030,"0,0252491694",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"24,65","14,44"
"low bq, bad alignment, many samples",UPN2_070,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5297,128,5449,"0,0234905487",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"24,28","14,58"
"low bq, bad alignment, many samples",UPN2_071,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9561,217,9811,"0,0221180308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"24,5","14,53"
"low bq, bad alignment, many samples",UPN2_072,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9426,222,9667,"0,0229647254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"24,65","14,58"
"low bq, bad alignment, many samples",UPN2_073,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9413,227,9674,"0,0234649576",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"24,76","14,48"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3453,72,3537,"0,0203562341",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"24,77","14,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_075,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),13208,275,13542,"0,0203071924",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"25,01","14,31"
"low bq, bad alignment, many samples",UPN2_076,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),7132,165,7324,"0,0225286729",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"24,4","14,26"
"low bq, bad alignment, many samples",UPN2_077,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9038,226,9297,"0,0243089169",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"24,44","14,2"
"low bq, bad alignment, many samples",UPN2_078,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9289,238,9567,"0,024877182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"24,19","14,62"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_079,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),6330,130,6490,"0,0200308166",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"24,72","14,64"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),12464,272,12799,"0,0212516603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"24,67","14,58"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_081,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),15513,335,15882,"0,0210930613",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"24,72","14,43"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_082,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5904,107,6027,"0,0177534428",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"24,86","14,72"
"low bq, bad alignment, many samples",UPN2_083,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9721,226,9973,"0,0226611852",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"24,36","14,42"
"low bq, bad alignment, many samples",UPN2_084,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),8008,208,8241,"0,0252396554",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"24,42","14,43"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_085,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5245,109,5375,"0,0202790698",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"24,87","14,36"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3076,65,3152,"0,0206218274",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"24,35","14,2"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_087,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9182,182,9405,"0,0193514088",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"24,81","14,57"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_088,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5961,116,6098,"0,0190226304",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"24,95","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_095,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),14129,155,14367,"0,0107886128",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"27,63","14,17"
"low bq, low freq, many artifacts",UPN2_102,19,33792356,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp322Ala/c.965A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),14214,148,14393,"0,0102827763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,05",Deleterious,19,Damaging,"27,76","14,05"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_059,19,33792359,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn321Thr/c.962A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5146,99,5272,"0,0187784522",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"26,12","14,46"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_060,19,33792359,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn321Thr/c.962A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),7956,134,8127,"0,016488249",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"26,44","14,43"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,19,33792359,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn321Thr/c.962A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9417,182,9649,"0,0188620582",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"25,87","14,46"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,19,33792359,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn321Thr/c.962A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9697,181,9918,"0,0182496471",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"25,59","14,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,19,33792359,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn321Thr/c.962A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),6393,89,6542,"0,0136044023",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"26,23","14,57"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,19,33792359,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn321Thr/c.962A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),6373,125,6530,"0,0191424196",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"26,08","14,56"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_065,19,33792359,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn321Thr/c.962A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5906,105,6052,"0,0173496365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"26,37","14,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_066,19,33792359,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn321Thr/c.962A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2961,39,3010,"0,0129568106",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"26,32","14,33"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_067,19,33792359,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn321Thr/c.962A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4744,91,4853,"0,0187512879",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"26,66","14,74"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_068,19,33792359,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn321Thr/c.962A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5169,93,5274,"0,0176336746",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"25,83","14,22"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_069,19,33792359,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn321Thr/c.962A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),8844,141,9010,"0,0156492786",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"26,18","14,34"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_070,19,33792359,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn321Thr/c.962A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5297,102,5431,"0,0187810716",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"25,65","14,81"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,19,33792359,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn321Thr/c.962A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9574,182,9791,"0,0185884996",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"26,31","14,41"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,19,33792359,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn321Thr/c.962A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9408,200,9650,"0,0207253886",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"26,25","14,1"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,19,33792359,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn321Thr/c.962A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9452,169,9651,"0,0175111387",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"26,29","14,5"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,19,33792359,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn321Thr/c.962A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3450,61,3528,"0,0172902494",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"26,67","14,43"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_075,19,33792359,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn321Thr/c.962A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),13266,201,13522,"0,014864665",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"26,83","14,86"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,19,33792359,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn321Thr/c.962A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),7124,156,7307,"0,021349391",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"25,94","14,65"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,19,33792359,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn321Thr/c.962A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9065,170,9274,"0,0183308173",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"26,15","14,97"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,19,33792359,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn321Thr/c.962A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9339,178,9544,"0,018650461",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"25,81","14,77"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_079,19,33792359,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn321Thr/c.962A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),6346,105,6472,"0,016223733",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"26,39",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,19,33792359,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn321Thr/c.962A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),12493,225,12782,"0,017602879",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"26,24","14,62"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_081,19,33792359,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn321Thr/c.962A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),15493,291,15848,"0,0183619384",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"26,46","14,53"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_082,19,33792359,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn321Thr/c.962A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5901,90,6015,"0,0149625935",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"26,59","14,61"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,19,33792359,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn321Thr/c.962A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9728,167,9943,"0,0167957357",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"25,89","14,44"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,19,33792359,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn321Thr/c.962A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),8061,138,8227,"0,0167740367",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"25,84","14,93"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_085,19,33792359,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn321Thr/c.962A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5245,88,5361,"0,016414848",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"26,21","14,65"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,19,33792359,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn321Thr/c.962A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3069,61,3142,"0,0194143857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"26,13","14,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_087,19,33792359,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn321Thr/c.962A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9156,166,9386,"0,0176859152",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"26,64","14,32"
"low bq, bad alignment, low freq, many artifacts",UPN2_088,19,33792359,T,G,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn321Thr/c.962A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5963,96,6088,"0,0157687254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,85",Deleterious,0,Damaging,"26,42","14,68"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_059,19,33792362,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp320Ala/c.959A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5179,54,5245,"0,0102955195",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,3,Damaging,"26,24","14,41"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,19,33792362,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp320Ala/c.959A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9442,109,9585,"0,0113719353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,3,Damaging,"25,91","14,43"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,19,33792362,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp320Ala/c.959A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9731,103,9867,"0,0104388365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,3,Damaging,"25,82","14,59"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,19,33792362,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp320Ala/c.959A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),6384,70,6495,"0,0107775212",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,3,Damaging,"26,17","15,2"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_067,19,33792362,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp320Ala/c.959A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4749,55,4824,"0,0114013267",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,3,Damaging,"26,7","15,05"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_068,19,33792362,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp320Ala/c.959A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5162,60,5243,"0,0114438299",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,3,Damaging,"26,13","14,22"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_069,19,33792362,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp320Ala/c.959A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),8817,94,8950,"0,0105027933",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,3,Damaging,"26,27","15,29"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_070,19,33792362,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp320Ala/c.959A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5300,67,5392,"0,012425816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,3,Damaging,"26,03","14,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,19,33792362,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp320Ala/c.959A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9598,108,9743,"0,0110848815",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,3,Damaging,"26,55","14,97"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,19,33792362,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp320Ala/c.959A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9463,102,9595,"0,0106305367",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,3,Damaging,"26,49","14,75"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,19,33792362,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp320Ala/c.959A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),7169,78,7277,"0,0107187028",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,3,Damaging,"26,05","14,63"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,19,33792362,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp320Ala/c.959A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9071,102,9212,"0,0110725141",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,3,Damaging,"26,23",15
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,19,33792362,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp320Ala/c.959A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9335,112,9484,"0,0118093631",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,3,Damaging,"25,85","14,73"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_079,19,33792362,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp320Ala/c.959A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),6338,71,6440,"0,0110248447",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,3,Damaging,"26,41","14,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,19,33792362,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp320Ala/c.959A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9716,120,9873,"0,0121543604",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,3,Damaging,"25,82","14,55"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_085,19,33792362,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp320Ala/c.959A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5255,55,5330,"0,0103189493",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,3,Damaging,"26,48","15,05"
"low bq, bad alignment, low freq, many artifacts",UPN2_088,19,33792362,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp320Ala/c.959A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5953,61,6045,"0,0100909843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,3,Damaging,"26,4","14,43"
"low bq, many samples, no database",UPN2_001,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),10422,958,11462,"0,083580527",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,31","15,08"
"low bq, many samples, no database",UPN2_014,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),15929,2646,18725,"0,1413084112",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,95","15,37"
"low bq, many samples, no database",UPN2_015,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),21168,4052,25447,"0,1592329155",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,96","15,57"
"low bq, many samples, no database",UPN2_016,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),10076,1613,11765,"0,1371015725",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,26,"15,63"
"low bq, many samples, no database",UPN2_017,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),6897,1204,8167,"0,1474225542",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,87","15,48"
"low bq, many samples, no database",UPN2_018,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),11484,1978,13549,"0,1459886338",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,97","15,67"
"low bq, many samples, no database",UPN2_019,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),11460,2086,13635,"0,1529886322",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"26,01","15,48"
"low bq, many samples, no database",UPN2_020,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),9847,1694,11618,"0,1458082286",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"26,04","15,58"
"low bq, many samples, no database",UPN2_021,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),14051,2494,16689,"0,1494397507",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"26,06","15,35"
"low bq, many samples, no database",UPN2_002,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),13788,1419,15287,"0,0928239681",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,13","15,17"
"low bq, bad alignment, many samples",UPN2_003,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2874,289,3193,"0,0905104917",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,35,Damaging,"25,26","14,99"
"low bq, many samples, no database",UPN2_022,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),15092,2675,17911,"0,1493495617",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,92","15,48"
"low bq, many samples, no database",UPN2_023,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),17298,2910,20370,"0,1428571429",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,9","15,54"
"low bq, many samples, no database",UPN2_041,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),60967,4519,66222,"0,0682401619",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,56","15,47"
"low bq, bad alignment, many samples",UPN2_024,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),6988,1263,8318,"0,1518393845",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,35,Damaging,"26,06","15,5"
"low bq, many samples, no database",UPN2_025,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),19712,3209,23093,"0,138959858",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,85","15,64"
"low bq, many samples, no database",UPN2_026,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),17411,3195,20743,"0,1540278648",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,84","15,58"
"low bq, bad alignment, many samples",UPN2_004,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2342,188,2551,"0,0736965896",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,35,Damaging,25,"14,85"
"low bq, many samples, no database",UPN2_027,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),19573,3590,23316,"0,1539715217",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,94","15,6"
"low bq, bad alignment, many samples",UPN2_089,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),12213,1809,14100,"0,1282978723",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,35,Damaging,"26,46","17,64"
"low bq, many samples, no database",UPN2_042,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),35516,2505,38425,"0,0651919323",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,52","15,52"
"low bq, bad alignment, many samples",UPN2_028,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),13673,2562,16356,"0,1566397652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,35,Damaging,"25,9","15,47"
"low bq, many samples, no database",UPN2_043,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),22858,1687,24833,"0,0679337978",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,66","15,42"
"low bq, many samples, no database",UPN2_044,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),10037,771,10933,"0,0705204427",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,45","15,44"
"low bq, many samples, no database",UPN2_029,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),16829,2938,19926,"0,1474455485",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,91","15,63"
"low bq, many samples, no database",UPN2_030,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),16869,3058,20091,"0,1522074561",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,97","15,57"
"low bq, many samples, no database",UPN2_031,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),11346,1934,13389,"0,1444469341",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,96","15,54"
"low bq, bad alignment, many samples",UPN2_005,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4685,426,5151,"0,0827023879",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,35,Damaging,"25,15","15,16"
"low bq, many samples, no database",UPN2_045,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),32187,2449,35036,"0,0698995319",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,55","15,4"
"low bq, many samples, no database",UPN2_032,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),6404,985,7435,"0,1324815064",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,8","15,37"
"low bq, many samples, no database",UPN2_046,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),31179,2397,33956,"0,0705913535",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,44","15,43"
"low bq, many samples, no database",UPN2_033,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),13179,2113,15441,"0,1368434687",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,96","15,64"
"low bq, many samples, no database",UPN2_034,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4962,884,5898,"0,1498813157",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"26,05","15,65"
"low bq, many samples, no database",UPN2_047,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),46555,3461,50572,"0,0684370798",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,53","15,44"
"low bq, many samples, no database",UPN2_048,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),51862,3895,56471,"0,0689734554",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,59","15,4"
"low bq, many samples, no database",UPN2_035,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),12855,2249,15219,"0,1477758066",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,95","15,71"
"low bq, many samples, no database",UPN2_036,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),25166,4149,29594,"0,1401973373",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,88","15,47"
"low bq, many samples, no database",UPN2_006,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),8177,848,9113,"0,0930538791",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,17","14,97"
"low bq, many samples, no database",UPN2_049,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),29156,1991,31521,"0,0631642397",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,43","15,34"
"low bq, many samples, no database",UPN2_050,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),28400,1983,30696,"0,064601251",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,53","15,28"
"low bq, many samples, no database",UPN2_037,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),28207,5284,33696,"0,1568138651",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"26,07","15,58"
"low bq, many samples, no database",UPN2_051,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),21815,1478,23566,"0,0627174743",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,54","15,42"
"low bq, many samples, no database",UPN2_052,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),24782,1944,27025,"0,071933395",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,46","15,25"
"low bq, many samples, no database",UPN2_038,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),30692,5535,36489,"0,1516895503",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,95","15,54"
"low bq, many samples, no database",UPN2_039,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),14154,2636,16932,"0,1556815497",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,93","15,57"
"low bq, many samples, no database",UPN2_053,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),30077,2178,32596,"0,0668180145",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,42","15,48"
"low bq, many samples, no database",UPN2_054,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),19599,1445,21305,"0,0678244544",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,23","15,39"
"low bq, many samples, no database",UPN2_007,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),28833,2730,31795,"0,085862557",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,54","15,13"
"low bq, many samples, no database",UPN2_008,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),45082,4974,50399,"0,0986924344",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,36","15,09"
"low bq, many samples, no database",UPN2_009,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),33768,3493,37512,"0,0931168693",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,36",15
"low bq, many samples, no database",UPN2_010,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),22588,2454,25251,"0,0971842699",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,29","15,03"
"low bq, many samples, no database",UPN2_011,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),26829,2669,29698,"0,0898713718",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,43","15,17"
"low bq, many samples, no database",UPN2_055,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),32024,2293,34727,"0,0660293144",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,46","15,24"
"low bq, many samples, no database",UPN2_056,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),18375,1343,19906,"0,0674670953",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,55","15,52"
"low bq, many samples, no database",UPN2_090,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),14149,1808,16064,"0,1125498008",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"26,5","17,71"
"low bq, many samples, no database",UPN2_057,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),28038,2069,30435,"0,067980943",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,54","15,61"
"low bq, many samples, no database",UPN2_058,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),27932,1950,30199,"0,0645716746",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,68","15,3"
"low bq, many samples, no database",UPN2_059,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3493,1716,5242,"0,327355971",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"27,07","20,84"
"low bq, many samples, no database",UPN2_012,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),15389,1571,17087,"0,0919412419",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,46","15,19"
"low bq, many samples, no database",UPN2_060,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),5310,2666,8039,"0,3316332877",1,1,0,0,1,1,0,0,4,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"27,21","20,63"
"low bq, many samples, no database",UPN2_040,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),7399,1261,8712,"0,1447428834",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"26,1","15,56"
"low bq, many samples, no database",UPN2_013,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),8812,850,9748,"0,0871973738",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"25,37","15,23"
"low bq, many samples, no database",UPN2_091,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),13132,1744,14926,"0,1168430926",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"26,43","17,58"
"low bq, many samples, no database",UPN2_092,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),7171,913,8129,"0,1123139378",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"26,23","17,55"
"low bq, many samples, no database",UPN2_093,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),8014,1033,9097,"0,1135539189",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"26,39","17,63"
"low bq, many samples, no database",UPN2_061,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),6242,3249,9557,"0,3399602386",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"26,95","20,86"
"low bq, many samples, no database",UPN2_062,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),6435,3315,9829,"0,3372672703",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"26,74","20,96"
"low bq, many samples, no database",UPN2_063,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4317,2127,6469,"0,328798887",1,1,0,0,1,1,0,0,4,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"27,13","21,04"
"low bq, many samples, no database",UPN2_064,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4220,2200,6471,"0,339978365",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"27,04","21,12"
"low bq, many samples, no database",UPN2_065,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3923,2045,6004,"0,3406062625",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"27,45","20,84"
"low bq, many samples, no database",UPN2_066,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1964,1012,2990,"0,3384615385",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"27,34","20,53"
"low bq, many samples, no database",UPN2_067,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3223,1539,4791,"0,3212273012",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"27,05","20,82"
"low bq, many samples, no database",UPN2_068,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3383,1786,5222,"0,3420145538",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"27,07","21,27"
"low bq, many samples, no database",UPN2_069,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),5911,2946,8916,"0,3304172275",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"27,24","20,67"
"low bq, many samples, no database",UPN2_070,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3508,1842,5379,"0,3424428332",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"27,15","20,85"
"low bq, many samples, no database",UPN2_071,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),6388,3256,9728,"0,3347039474",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"27,03","20,96"
"low bq, many samples, no database",UPN2_072,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),6222,3253,9551,"0,3405926081",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"27,34","21,11"
"low bq, many samples, no database",UPN2_073,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),6289,3215,9580,"0,3355949896",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"27,25","20,83"
"low bq, many samples, no database",UPN2_074,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2342,1118,3487,"0,3206194436",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"26,85","21,04"
"low bq, many samples, no database",UPN2_075,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),8969,4303,13364,"0,3219844358",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"27,13","20,66"
"low bq, many samples, no database",UPN2_076,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4703,2502,7266,"0,3443435178",1,1,0,0,1,1,0,0,4,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"27,19","21,03"
"low bq, many samples, no database",UPN2_077,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),6062,3059,9196,"0,3326446281",1,1,0,0,1,1,0,0,4,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"27,14","20,85"
"low bq, many samples, no database",UPN2_078,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),6184,3215,9452,"0,340139653",1,1,0,0,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"26,87","21,24"
"low bq, many samples, no database",UPN2_079,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4239,2128,6423,"0,331309357",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"27,18","20,82"
"low bq, many samples, no database",UPN2_080,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),8373,4207,12685,"0,331651557",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"27,21","20,95"
"low bq, many samples, no database",UPN2_081,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),10205,5426,15733,"0,3448801881",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"27,41","20,92"
"low bq, many samples, no database",UPN2_082,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3967,1959,5963,"0,3285259098",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"27,41","20,7"
"low bq, many samples, no database",UPN2_083,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),6466,3305,9838,"0,3359422647",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"26,97","20,87"
"low bq, many samples, no database",UPN2_084,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),5246,2802,8112,"0,3454142012",1,1,0,0,1,1,0,0,4,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"27,3","20,86"
"low bq, many samples, no database",UPN2_085,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3475,1816,5323,"0,3411609994",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"27,29","21,02"
"low bq, many samples, no database",UPN2_086,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2046,1054,3119,"0,3379288233",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"27,24","20,83"
"low bq, many samples, no database",UPN2_087,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),6180,3065,9300,"0,3295698925",1,1,0,0,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"27,14","20,71"
"low bq, many samples, no database",UPN2_088,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4048,1944,6031,"0,3223346045",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"27,19","20,88"
"low bq, many samples, no database",UPN2_094,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),15551,2128,17760,"0,1198198198",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"26,35","17,55"
"low bq, many samples, no database",UPN2_095,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),12405,1812,14278,"0,1269085306",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"26,27","18,15"
"low bq, many samples, no database",UPN2_096,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),12782,1704,14576,"0,1169045005",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"26,43","17,75"
"low bq, many samples, no database",UPN2_097,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),18095,2478,20687,"0,1197853725",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"26,37","17,65"
"low bq, many samples, no database",UPN2_098,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),13429,1708,15226,"0,1121765401",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"26,28","17,64"
"low bq, many samples, no database",UPN2_099,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),6870,903,7819,"0,1154879141",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"26,2","17,66"
"low bq, many samples, no database",UPN2_100,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),10312,1266,11630,"0,1088564058",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"26,5","17,63"
"low bq, many samples, no database",UPN2_101,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),11053,1576,12694,"0,1241531432",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"26,17","17,36"
"low bq, many samples, no database",UPN2_102,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),12561,1723,14332,"0,1202204856",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"26,12","17,6"
"low bq, bad alignment",UPN2_103,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),10912,1520,12495,"0,1216486595",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,35,Damaging,"26,03","17,61"
"low bq, many samples, no database",UPN2_104,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),14300,1941,16323,"0,1189119647",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"26,28","17,66"
"low bq, many samples, no database",UPN2_105,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),13606,1879,15563,"0,1207350768",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"26,29","17,94"
"low bq, many samples, no database",UPN2_106,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),18503,2502,21118,"0,1184771285",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"26,47","17,66"
"low bq, many samples, no database",UPN2_107,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),21023,2717,23857,"0,1138869095",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"26,29","17,63"
"low bq, many samples, no database",UPN2_108,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),16866,2179,19133,"0,1138870015",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"26,38","17,56"
"low bq, many samples, no database",UPN2_109,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),16301,2328,18718,"0,124372262",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"26,41","17,61"
"low bq, many samples, no database",UPN2_110,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),16298,2262,18664,"0,1211958851",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"26,38","17,69"
"low bq, many samples, no database",UPN2_111,19,33792364,A,C,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser319Arg/c.957T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),13732,1896,15715,"0,1206490614",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,035",Damaging,"26,33","17,57"
"low bq, low freq, many artifacts",UPN2_044,19,33792368,G,T,missense_variant(MODERATE|MISSENSE|aCc/aAc|p.Thr318Asn/c.953C>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),5426,76,5519,"0,0137706106",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,59",Deleterious,"0,095",Tolerated,"32,94","26,84"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_041,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),32658,341,33189,"0,0102744885",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"25,15","14,58"
"low bq, bad alignment, many samples",UPN2_089,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),6866,161,7062,"0,0227980742",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"22,02","14,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),18921,199,19233,"0,0103467998",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"24,82","14,67"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_044,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5432,60,5519,"0,0108715347",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"24,66","14,73"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),17272,185,17579,"0,0105239206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"24,7","14,65"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),16752,179,17018,"0,0105182748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"24,37","14,59"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),24929,271,25362,"0,0106852772",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"25,11","14,61"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),15549,169,15815,"0,0106860575",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"24,33","15,08"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),13350,151,13585,"0,0111152006",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"24,06","14,7"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),16064,187,16344,"0,0114415076",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,24,"14,59"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),10514,130,10691,"0,0121597605",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"23,65","14,82"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),17126,191,17423,"0,0109625208",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"24,29","14,67"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_090,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),7883,158,8065,"0,0195908246",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"22,1","14,59"
"low bq, bad alignment, many samples",UPN2_059,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2497,124,2636,"0,0470409712",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"19,56","14,45"
"low bq, bad alignment, many samples",UPN2_060,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3811,213,4049,"0,0526055816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"19,69","14,5"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_091,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),7306,139,7477,"0,0185903437",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"21,97","14,55"
"low bq, bad alignment, many samples",UPN2_092,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3956,93,4064,"0,0228838583",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"21,6","14,37"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_093,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4451,79,4556,"0,0173397717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"21,8","14,42"
"low bq, bad alignment, many samples",UPN2_061,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4500,306,4828,"0,0633802817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"19,23","14,77"
"low bq, bad alignment, many samples",UPN2_062,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4640,292,4960,"0,0588709677",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"18,97","14,34"
"low bq, bad alignment, many samples",UPN2_063,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3054,203,3269,"0,0620985011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"19,82","14,32"
"low bq, bad alignment, many samples",UPN2_064,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3060,171,3258,"0,0524861878",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"19,52","14,33"
"low bq, bad alignment, many samples",UPN2_065,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2847,159,3030,"0,0524752475",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"19,78","14,13"
"low bq, bad alignment, many samples",UPN2_066,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1414,75,1499,"0,0500333556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"20,4",14
"low bq, bad alignment, many samples",UPN2_067,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2266,147,2424,"0,0606435644",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"19,95","14,28"
"low bq, bad alignment, many samples",UPN2_068,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2484,138,2638,"0,0523123578",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"19,77",14
"low bq, bad alignment, many samples",UPN2_069,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4220,266,4503,"0,05907173",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"20,02","14,33"
"low bq, bad alignment, many samples",UPN2_070,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2545,154,2717,"0,0566801619",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"19,61","14,33"
"low bq, bad alignment, many samples",UPN2_071,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4601,277,4899,"0,0565421515",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"19,96","14,19"
"low bq, bad alignment, many samples",UPN2_072,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4539,253,4808,"0,0526206323",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"20,05","14,27"
"low bq, bad alignment, many samples",UPN2_073,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4551,255,4831,"0,0527841027",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"20,03","14,42"
"low bq, bad alignment, many samples",UPN2_074,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1653,99,1760,"0,05625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"19,39","14,71"
"low bq, bad alignment, many samples",UPN2_075,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),6379,352,6764,"0,0520402129",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"20,19","14,42"
"low bq, bad alignment, many samples",UPN2_076,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3424,214,3655,"0,0585499316",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"19,45","14,64"
"low bq, bad alignment, many samples",UPN2_077,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4355,255,4638,"0,0549805951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"19,72","14,8"
"low bq, bad alignment, many samples",UPN2_078,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4490,259,4775,"0,0542408377",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"19,29","14,71"
"low bq, bad alignment, many samples",UPN2_079,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3043,168,3234,"0,0519480519",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"19,64","14,46"
"low bq, bad alignment, many samples",UPN2_080,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5989,358,6384,"0,0560776942",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"19,87","14,44"
"low bq, bad alignment, many samples",UPN2_081,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),7466,415,7912,"0,0524519717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"20,07","14,46"
"low bq, bad alignment, many samples",UPN2_082,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2847,145,3011,"0,0481567586",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"20,13","14,37"
"low bq, bad alignment, many samples",UPN2_083,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4647,317,4981,"0,063641839",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"19,16","14,49"
"low bq, bad alignment, many samples",UPN2_084,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3894,207,4114,"0,0503159942",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"19,36","14,24"
"low bq, bad alignment, many samples",UPN2_085,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2513,150,2678,"0,0560119492",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"19,97","14,22"
"low bq, bad alignment, many samples",UPN2_086,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1469,93,1570,"0,0592356688",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"19,21","14,83"
"low bq, bad alignment, many samples",UPN2_087,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4418,251,4696,"0,0534497445",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"20,06","14,17"
"low bq, bad alignment, many samples",UPN2_088,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2873,155,3043,"0,0509365757",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"19,52","14,4"
"low bq, bad alignment, many samples",UPN2_094,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),8674,206,8921,"0,0230915817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"21,59","14,13"
"low bq, bad alignment, many samples",UPN2_095,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),6946,186,7161,"0,025974026",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"20,94","14,46"
"low bq, bad alignment, many samples",UPN2_096,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),7123,169,7326,"0,0230685231",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"21,82","14,57"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_097,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),10110,223,10378,"0,0214877626",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"21,8","14,14"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_098,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),7432,165,7633,"0,0216166645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"21,49","14,77"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_099,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3827,80,3921,"0,0204029584",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"21,33","14,09"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_100,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),5702,120,5835,"0,0205655527",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"22,51","14,51"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_101,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),6182,138,6349,"0,0217357064",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"20,92","14,36"
"low bq, bad alignment, many samples",UPN2_102,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),6971,174,7171,"0,0242643983",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"20,76","14,18"
"low bq, bad alignment, many samples",UPN2_103,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),6099,155,6269,"0,0247248365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"20,49","14,05"
"low bq, bad alignment, many samples",UPN2_104,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),7974,184,8201,"0,0224362883",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"21,38","14,18"
"low bq, bad alignment, many samples",UPN2_105,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),7606,176,7807,"0,0225438709",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"21,32","14,12"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_106,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),10329,218,10602,"0,0205621581",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"22,44","14,34"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_107,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),11689,221,11955,"0,0184859891",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"21,92","14,27"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_108,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9361,191,9607,"0,0198813365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"22,38","14,39"
"low bq, bad alignment, many samples",UPN2_109,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9129,213,9392,"0,0226788756",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"21,72","14,47"
"low bq, bad alignment, many samples",UPN2_110,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),9107,209,9367,"0,0223123732",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"21,91","14,36"
"low bq, bad alignment",UPN2_111,19,33792369,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr318Pro/c.952A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),7677,180,7883,"0,0228339465",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,6",Deleterious,"0,05",Damaging,"21,4","14,21"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_059,19,33792374,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu316Ala/c.947A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2589,30,2637,"0,0113765643",0,0,0,0,1,0,0,0,1,NO,NO,COSM1392673,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,8",Deleterious,7,Damaging,"26,39",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_060,19,33792374,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu316Ala/c.947A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3992,46,4053,"0,0113496176",0,0,0,0,1,0,0,0,1,NO,NO,COSM1392673,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,8",Deleterious,7,Damaging,"26,67","14,15"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,19,33792374,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu316Ala/c.947A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4741,58,4830,"0,0120082816",0,0,0,0,1,0,0,0,1,NO,NO,COSM1392673,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,8",Deleterious,7,Damaging,"25,98",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,19,33792374,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu316Ala/c.947A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4885,56,4960,"0,0112903226",0,0,0,0,1,0,0,0,1,NO,NO,COSM1392673,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,8",Deleterious,7,Damaging,"25,21","14,52"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,19,33792374,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu316Ala/c.947A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3204,35,3259,"0,0107394906",0,0,0,0,1,0,0,0,1,NO,NO,COSM1392673,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,8",Deleterious,7,Damaging,"26,39","14,63"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_070,19,33792374,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu316Ala/c.947A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2670,34,2717,"0,012513802",0,0,0,0,1,0,0,0,1,NO,NO,COSM1392673,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,8",Deleterious,7,Damaging,"26,02","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_072,19,33792374,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu316Ala/c.947A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4728,51,4809,"0,0106051154",0,0,0,0,1,0,0,0,1,NO,NO,COSM1392673,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,8",Deleterious,7,Damaging,"27,13",14
"low bq, low freq, many artifacts, many samples",UPN2_073,19,33792374,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu316Ala/c.947A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4753,53,4835,"0,0109617373",0,0,0,0,1,0,0,0,1,NO,NO,COSM1392673,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,8",Deleterious,7,Damaging,"27,07","15,77"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,19,33792374,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu316Ala/c.947A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3603,42,3658,"0,011481684",0,0,0,0,1,0,0,0,1,NO,NO,COSM1392673,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,8",Deleterious,7,Damaging,"26,4","14,69"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,19,33792374,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu316Ala/c.947A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4567,56,4639,"0,0120715671",0,0,0,0,1,0,0,0,1,NO,NO,COSM1392673,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,8",Deleterious,7,Damaging,"26,41","14,82"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_079,19,33792374,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu316Ala/c.947A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3187,33,3234,"0,0102040816",0,0,0,0,1,0,0,0,1,NO,NO,COSM1392673,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,8",Deleterious,7,Damaging,"26,99","15,09"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,19,33792374,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu316Ala/c.947A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),6283,64,6386,"0,010021923",0,0,0,0,1,0,0,0,1,NO,NO,COSM1392673,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,8",Deleterious,7,Damaging,"26,87","14,48"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,19,33792374,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu316Ala/c.947A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4895,56,4980,"0,0112449799",0,0,0,0,1,0,0,0,1,NO,NO,COSM1392673,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,8",Deleterious,7,Damaging,"25,86","14,52"
"low bq, bad alignment, low freq, many artifacts",UPN2_088,19,33792374,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu316Ala/c.947A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3000,31,3044,"0,0101839685",0,0,0,0,1,0,0,0,1,NO,NO,COSM1392673,large_intestine,1,NO,NO,NO,NO,NO,NO,"-5,8",Deleterious,7,Damaging,"26,71","14,58"
"low bq, low freq, many artifacts",UPN2_067,19,33792384,T,G,missense_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys313Gln/c.937A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2401,26,2431,"0,0106951872",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,58",Deleterious,31,Damaging,"28,79","15,12"
"low bq, bad alignment, many samples",UPN2_059,19,33792393,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr310Pro/c.928A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2558,66,2644,"0,0249621785",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,1,Damaging,"23,8","14,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_060,19,33792393,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr310Pro/c.928A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3968,82,4066,"0,0201672405",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,1,Damaging,"23,71","14,57"
"low bq, bad alignment, many samples",UPN2_061,19,33792393,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr310Pro/c.928A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4699,121,4843,"0,0249845137",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,1,Damaging,"23,33","14,17"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,19,33792393,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr310Pro/c.928A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4853,108,4977,"0,0216998192",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,1,Damaging,"23,07","14,6"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,19,33792393,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr310Pro/c.928A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3200,62,3277,"0,0189197437",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,1,Damaging,"23,8","14,11"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,19,33792393,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr310Pro/c.928A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3192,64,3268,"0,0195838433",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,1,Damaging,"23,63","14,11"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_065,19,33792393,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr310Pro/c.928A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2980,46,3041,"0,0151266031",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,1,Damaging,"24,04","14,59"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_066,19,33792393,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr310Pro/c.928A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1469,30,1504,"0,0199468085",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,1,Damaging,"23,85","14,43"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_067,19,33792393,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr310Pro/c.928A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2370,52,2431,"0,0213903743",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,1,Damaging,"24,66","14,62"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_068,19,33792393,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr310Pro/c.928A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2583,49,2645,"0,0185255198",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,1,Damaging,"23,88",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_069,19,33792393,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr310Pro/c.928A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4411,91,4511,"0,0201729107",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,1,Damaging,"23,83","15,01"
"low bq, bad alignment, many samples",UPN2_070,19,33792393,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr310Pro/c.928A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2639,66,2722,"0,0242468773",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,1,Damaging,"23,65","14,38"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,19,33792393,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr310Pro/c.928A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4777,101,4905,"0,0205912334",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,1,Damaging,"24,07","14,27"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,19,33792393,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr310Pro/c.928A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4718,88,4822,"0,0182496889",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,1,Damaging,"24,07","14,33"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,19,33792393,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr310Pro/c.928A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4740,81,4840,"0,0167355372",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,1,Damaging,"24,13","14,17"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,19,33792393,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr310Pro/c.928A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1738,22,1767,"0,012450481",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,1,Damaging,"23,55",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_075,19,33792393,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr310Pro/c.928A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),6626,125,6781,"0,0184338593",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,1,Damaging,"24,5","15,15"
"low bq, bad alignment, many samples",UPN2_076,19,33792393,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr310Pro/c.928A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3572,82,3666,"0,0223677032",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,1,Damaging,"23,45","14,33"
"low bq, bad alignment, many samples",UPN2_077,19,33792393,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr310Pro/c.928A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4498,117,4645,"0,0251883746",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,1,Damaging,"23,58","14,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,19,33792393,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr310Pro/c.928A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4660,101,4784,"0,0211120401",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,1,Damaging,"23,17","14,49"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_079,19,33792393,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr310Pro/c.928A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3164,62,3241,"0,0191298982",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,1,Damaging,"23,97","14,29"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,19,33792393,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr310Pro/c.928A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),6256,104,6395,"0,0162627052",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,1,Damaging,"23,89","14,65"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_081,19,33792393,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr310Pro/c.928A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),7732,162,7936,"0,0204133065",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,1,Damaging,"24,37","14,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_082,19,33792393,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr310Pro/c.928A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2953,55,3017,"0,0182300298",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,1,Damaging,"24,32","14,58"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,19,33792393,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr310Pro/c.928A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4875,87,4993,"0,0174243942",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,1,Damaging,"23,23","14,53"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,19,33792393,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr310Pro/c.928A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4028,81,4125,"0,0196363636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,1,Damaging,"23,46","14,53"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_085,19,33792393,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr310Pro/c.928A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2614,58,2688,"0,021577381",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,1,Damaging,"23,79","15,19"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,19,33792393,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr310Pro/c.928A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1543,27,1574,"0,0171537484",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,1,Damaging,"23,1","14,26"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_087,19,33792393,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr310Pro/c.928A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4590,90,4704,"0,0191326531",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,1,Damaging,"24,29","14,72"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_088,19,33792393,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr310Pro/c.928A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2975,58,3046,"0,0190413657",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,1,Damaging,"24,09",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_094,19,33792393,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr310Pro/c.928A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),8814,90,8931,"0,010077259",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,1,Damaging,"26,92","14,87"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_095,19,33792393,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr310Pro/c.928A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),7066,76,7170,"0,0105997211",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,1,Damaging,"26,43","15,22"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_101,19,33792393,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr310Pro/c.928A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),6264,65,6361,"0,0102185191",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,1,Damaging,"26,59","14,98"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_103,19,33792393,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr310Pro/c.928A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),6180,67,6273,"0,010680695",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,1,Damaging,"26,25",14
"low bq, bad alignment, low freq, many artifacts",UPN2_104,19,33792393,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr310Pro/c.928A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),8086,84,8207,"0,0102351651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,6",Deleterious,1,Damaging,"26,75","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_043,19,33792398,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val308Glu/c.923T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),12274,132,12461,"0,0105930503",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,39,Damaging,"33,46","17,52"
"low bq, low freq, many artifacts, many samples",UPN2_046,19,33792398,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val308Glu/c.923T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),16785,171,17040,"0,0100352113",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,39,Damaging,"33,4","17,77"
"low bq, low freq, many artifacts, many samples",UPN2_053,19,33792398,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val308Glu/c.923T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),16122,179,16371,"0,0109339686",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,39,Damaging,"33,3","19,58"
"low bq, low freq, many artifacts",UPN2_055,19,33792398,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val308Glu/c.923T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),17169,204,17458,"0,0116851873",0,0,1,0,1,0,1,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,"0,039",Damaging,"33,33","18,64"
"low bq, low freq, many artifacts",UPN2_057,19,33792398,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val308Glu/c.923T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),15022,167,15282,"0,010927889",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,39,Damaging,"33,43","18,16"
"low bq, low freq, many artifacts",UPN2_058,19,33792398,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val308Glu/c.923T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),14929,161,15160,"0,0106200528",0,0,0,0,1,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,81",Deleterious,"0,039",Damaging,"33,47","19,22"
"low bq, bad alignment, low freq, many artifacts",UPN2_083,19,33792426,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser299Arg/c.895A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4936,51,5004,"0,0101918465",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,86",Deleterious,0,Damaging,"26,75","14,27"
"low freq, many artifacts",UPN2_041,19,33792477,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser282Gly/c.844A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),33386,364,33803,"0,010768275",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,89",Deleterious,"0,002",Damaging,"31,45","31,26"
"low freq, many artifacts, many samples",UPN2_044,19,33792477,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser282Gly/c.844A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),5523,62,5594,"0,0110833035",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,89",Deleterious,2,Damaging,"31,41",32
"low freq, many artifacts, many samples",UPN2_086,19,33792477,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser282Gly/c.844A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1543,22,1567,"0,014039566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,89",Deleterious,2,Damaging,"31,07","31,18"
"many samples, neutral effect, low freq",UPN2_001,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4391,1341,5746,"0,2333797424",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,27","31,56"
"many samples, neutral effect, low freq",UPN2_014,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),7893,1473,9389,"0,1568857173",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,47","31,64"
"many samples, neutral effect, low freq",UPN2_015,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),11061,1646,12752,"0,1290777917",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,36","31,58"
"many samples, neutral effect, low freq",UPN2_016,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4996,884,5899,"0,1498559078",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,48","31,57"
"many samples, neutral effect, low freq",UPN2_017,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3465,629,4100,"0,1534146341",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,41","31,66"
"many samples, neutral effect, low freq",UPN2_018,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),5797,1008,6836,"0,1474546518",0,1,0,1,1,1,0,0,4,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,48","31,65"
"many samples, neutral effect, low freq",UPN2_019,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),5689,1105,6821,"0,1619997068",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,44","31,61"
"many samples, neutral effect, low freq",UPN2_020,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4851,945,5816,"0,1624828061",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,49","31,72"
"many samples, neutral effect, low freq",UPN2_021,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),6996,1356,8380,"0,1618138425",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,44","31,46"
"many samples, neutral effect, low freq",UPN2_002,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),5850,1786,7651,"0,2334335381",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,09","31,71"
"many samples, neutral effect, low freq",UPN2_003,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1248,332,1586,"0,209331652",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,15","31,44"
"many samples, neutral effect, low freq",UPN2_022,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),7605,1387,9016,"0,153837622",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,31","31,62"
"many samples, neutral effect, low freq",UPN2_023,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),8755,1536,10327,"0,1487363223",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,45","31,67"
"many samples, neutral effect, low freq",UPN2_041,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),31344,2195,33633,"0,0652632831",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,37","31,45"
"many samples, neutral effect, low freq",UPN2_024,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3636,514,4167,"0,123350132",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,39","31,54"
"many samples, neutral effect, low freq",UPN2_025,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),9780,1727,11541,"0,1496404124",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,45","31,53"
"many samples, neutral effect, low freq",UPN2_026,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),8799,1580,10409,"0,1517917187",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,24","31,65"
"many samples, neutral effect, low freq",UPN2_004,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),971,290,1266,"0,2290679305",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,17","31,64"
"many samples, neutral effect, low freq",UPN2_027,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),9647,2007,11678,"0,1718616201",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,37","31,63"
"many samples, neutral effect, low freq",UPN2_089,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),6594,444,7055,"0,0629340893",0,0,0,1,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,47","31,43"
"many samples, neutral effect, low freq",UPN2_042,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),17947,1603,19600,"0,0817857143",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,4","31,54"
"many samples, neutral effect, low freq",UPN2_028,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),6937,1200,8163,"0,1470047777",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,31","31,62"
"many samples, neutral effect, low freq",UPN2_043,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),12465,1054,13560,"0,0777286136",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,76","31,5"
"many samples, neutral effect, low freq",UPN2_044,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4974,550,5538,"0,0993138317",0,1,0,1,1,1,0,0,4,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,33","31,59"
"many samples, neutral effect, low freq",UPN2_029,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),8432,1530,9984,"0,1532451923",0,1,0,1,1,1,0,0,4,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,44","31,48"
"many samples, neutral effect, low freq",UPN2_030,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),8491,1509,10032,"0,1504186603",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,33","31,6"
"many samples, neutral effect, low freq",UPN2_031,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),5672,1030,6728,"0,1530915577",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,42","31,66"
"many samples, neutral effect, low freq",UPN2_005,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1942,627,2579,"0,2431174874",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,1","31,72"
"many samples, neutral effect, low freq",UPN2_045,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),18643,1144,19833,"0,0576816417",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,75","31,49"
"many samples, neutral effect, low freq",UPN2_032,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3267,549,3830,"0,1433420366",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,47","31,6"
"many samples, neutral effect, low freq",UPN2_046,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),15167,1791,16998,"0,1053653371",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,24","31,55"
"many samples, neutral effect, low freq",UPN2_033,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),7014,1085,8115,"0,1337030191",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,66","31,72"
"many samples, neutral effect, low freq",UPN2_034,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2772,380,3159,"0,1202912314",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,74","31,53"
"many samples, neutral effect, low freq",UPN2_047,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),23545,2253,25852,"0,0871499304",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,35","31,45"
"many samples, neutral effect, low freq",UPN2_048,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),25478,2686,28283,"0,0949687091",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,33","31,57"
"many samples, neutral effect, low freq",UPN2_035,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),6420,1174,7616,"0,1541491597",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,44","31,64"
"many samples, neutral effect, low freq",UPN2_036,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),12469,2308,14819,"0,1557460018",0,1,0,1,1,1,0,0,4,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,44","31,53"
"many samples, neutral effect, low freq",UPN2_006,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3637,984,4628,"0,2126188418",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,13","31,65"
many samples,UPN2_049,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),14461,1392,15877,"0,0876739938",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,844,Tolerated,"31,26","31,46"
"many samples, neutral effect, low freq",UPN2_050,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),16222,852,17124,"0,0497547302",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,63","31,46"
"many samples, neutral effect, low freq",UPN2_037,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),14542,2411,17021,"0,1416485518",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,4","31,57"
"many samples, neutral effect, low freq",UPN2_051,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),11615,864,12500,"0,06912",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,57","31,48"
"many samples, neutral effect, low freq",UPN2_052,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),14209,788,15033,"0,0524180137",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,61","31,61"
"many samples, neutral effect, low freq",UPN2_038,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),15514,2745,18315,"0,1498771499",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,41","31,58"
"many samples, neutral effect, low freq",UPN2_039,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),7164,1308,8496,"0,1539548023",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,32","31,53"
"many samples, neutral effect, low freq",UPN2_053,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),16011,1616,17667,"0,0914699723",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,53","31,5"
"many samples, neutral effect, low freq",UPN2_054,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),10130,813,10966,"0,0741382455",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,21","31,43"
"many samples, neutral effect, low freq",UPN2_007,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),12575,3276,15906,"0,2059600151",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,37","31,64"
"many samples, neutral effect, low freq",UPN2_008,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),20131,5126,25332,"0,2023527554",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,27","31,63"
"many samples, neutral effect, low freq",UPN2_009,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),15049,3578,18685,"0,1914905004",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,25","31,52"
"many samples, neutral effect, low freq",UPN2_010,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),10031,2521,12580,"0,2003974563",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,24","31,56"
"many samples, neutral effect, low freq",UPN2_011,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),11746,3036,14823,"0,2048168387",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,32","31,64"
many samples,UPN2_055,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),15943,1487,17472,"0,0851076007",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,844,Tolerated,"31,24","31,42"
many samples,UPN2_056,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),9133,808,9964,"0,081091931",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,844,Tolerated,"31,27","31,38"
many samples,UPN2_090,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),7658,413,8074,"0,0511518454",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,844,Tolerated,"31,51","31,54"
"many samples, neutral effect, low freq",UPN2_057,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),14001,1437,15464,"0,0929255044",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,37","31,49"
"many samples, neutral effect, low freq",UPN2_058,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),13561,1788,15411,"0,1160210239",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,4","31,56"
"many samples, neutral effect, low freq",UPN2_059,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2205,427,2635,"0,1620493359",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"30,92","31,6"
"many samples, neutral effect, low freq",UPN2_012,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),6902,1626,8549,"0,1901976839",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,3","31,69"
"many samples, neutral effect, low freq",UPN2_060,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3275,743,4025,"0,1845962733",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,04","31,62"
"many samples, neutral effect, low freq",UPN2_040,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3721,617,4351,"0,1418064813",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,44","31,72"
"many samples, neutral effect, low freq",UPN2_013,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3849,1000,4859,"0,2058036633",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,3","31,63"
"many samples, neutral effect, low freq",UPN2_091,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),6940,518,7467,"0,069371903",0,0,0,1,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,57","31,69"
"many samples, neutral effect, low freq",UPN2_092,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3816,232,4051,"0,0572698099",0,0,0,1,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,5","31,42"
"many samples, neutral effect, low freq",UPN2_093,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4247,277,4532,"0,0611209179",0,0,0,1,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,51","31,38"
"many samples, neutral effect, low freq",UPN2_061,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3882,859,4749,"0,1808801853",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"30,96","31,68"
"many samples, neutral effect, low freq",UPN2_062,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4036,910,4957,"0,1835787775",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"30,81","31,68"
"many samples, neutral effect, low freq",UPN2_063,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2621,614,3240,"0,1895061728",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,04","31,54"
"many samples, neutral effect, low freq",UPN2_064,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2588,648,3247,"0,1995688328",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,19","31,48"
"many samples, neutral effect, low freq",UPN2_065,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2534,489,3031,"0,1613328934",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,2","31,57"
"many samples, neutral effect, low freq",UPN2_066,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1257,225,1486,"0,1514131898",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,04","31,6"
"many samples, neutral effect, low freq",UPN2_067,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1981,420,2403,"0,1747815231",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,23","31,79"
"many samples, neutral effect, low freq",UPN2_068,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2172,437,2614,"0,1671767406",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,06","31,76"
"many samples, neutral effect, low freq",UPN2_069,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3727,740,4478,"0,1652523448",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"30,93","31,6"
"many samples, neutral effect, low freq",UPN2_070,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2210,489,2705,"0,1807763401",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"30,82","31,76"
"many samples, neutral effect, low freq",UPN2_071,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3970,882,4862,"0,1814068285",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,17","31,74"
"many samples, neutral effect, low freq",UPN2_072,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3956,835,4804,"0,1738134888",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,12","31,55"
"many samples, neutral effect, low freq",UPN2_073,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4003,780,4797,"0,162601626",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,03","31,71"
"many samples, neutral effect, low freq",UPN2_074,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1419,306,1733,"0,1765724178",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,09","31,44"
"many samples, neutral effect, low freq",UPN2_075,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),5592,1128,6734,"0,1675081675",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,11","31,6"
"many samples, neutral effect, low freq",UPN2_076,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3043,604,3661,"0,1649822453",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,02","31,76"
"many samples, neutral effect, low freq",UPN2_077,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3869,749,4627,"0,1618759455",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,03","31,72"
"many samples, neutral effect, low freq",UPN2_078,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3962,806,4775,"0,1687958115",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"30,94","31,59"
"many samples, neutral effect, low freq",UPN2_079,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2636,555,3209,"0,1729510751",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,09","31,6"
"many samples, neutral effect, low freq",UPN2_080,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),5300,1047,6372,"0,1643126177",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,2","31,58"
"many samples, neutral effect, low freq",UPN2_081,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),6667,1244,7919,"0,1570905417",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,16","31,66"
"many samples, neutral effect, low freq",UPN2_082,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2580,420,3007,"0,1396740938",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,16","31,75"
"many samples, neutral effect, low freq",UPN2_083,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4004,921,4948,"0,1861358124",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"30,92","31,67"
"many samples, neutral effect, low freq",UPN2_084,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3455,640,4111,"0,1556798832",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,01","31,86"
"many samples, neutral effect, low freq",UPN2_085,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2209,427,2647,"0,1613146959",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,27","31,7"
"many samples, neutral effect, low freq",UPN2_086,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1314,246,1565,"0,1571884984",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"30,86","31,91"
"many samples, neutral effect, low freq",UPN2_087,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3901,752,4659,"0,1614080275",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,18","31,72"
"many samples, neutral effect, low freq",UPN2_088,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2471,556,3039,"0,1829549194",0,1,0,1,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,09","31,69"
many samples,UPN2_094,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),8430,460,8912,"0,0516157989",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,844,Tolerated,"31,47","31,69"
"many samples, neutral effect, low freq",UPN2_095,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),6702,429,7149,"0,0600083928",0,0,0,1,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,42","31,58"
many samples,UPN2_096,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),6919,385,7313,"0,0526459729",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,844,Tolerated,"31,58","31,66"
"many samples, neutral effect, low freq",UPN2_097,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),9626,706,10353,"0,0681927944",0,0,0,1,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,53","31,64"
"many samples, neutral effect, low freq",UPN2_098,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),7159,461,7631,"0,0604114795",0,0,0,1,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,45","31,64"
"many samples, neutral effect, low freq",UPN2_099,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3651,246,3905,"0,0629961588",0,0,0,1,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,47","31,47"
many samples,UPN2_100,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),5571,265,5849,"0,0453068901",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,844,Tolerated,"31,58","31,4"
many samples,UPN2_101,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),6160,259,6432,"0,0402674129",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,844,Tolerated,"31,51","31,32"
many samples,UPN2_102,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),6817,362,7199,"0,0502847618",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,844,Tolerated,"31,41","31,83"
"many samples, neutral effect, low freq",UPN2_103,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),5865,371,6247,"0,0593885065",0,0,0,1,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,46","31,43"
"many samples, neutral effect, low freq",UPN2_104,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),7636,535,8191,"0,0653155903",0,0,0,1,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,47","31,61"
"many samples, neutral effect, low freq",UPN2_105,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),7313,463,7791,"0,0594275446",0,0,0,1,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,46","31,56"
many samples,UPN2_106,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),10101,467,10593,"0,044085717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,844,Tolerated,"31,54","31,49"
"many samples, neutral effect, low freq",UPN2_107,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),11284,612,11922,"0,0513336688",0,0,0,1,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,53","31,46"
many samples,UPN2_108,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),9154,421,9602,"0,0438450323",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,844,Tolerated,"31,49","31,29"
many samples,UPN2_109,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),8922,428,9366,"0,0456972026",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,844,Tolerated,"31,46","31,74"
"inspected, low freq, neutral effect",UPN2_110,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),9027,317,9356,"0,0338820009",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,844,Tolerated,"31,54","31,04"
"many samples, neutral effect, low freq",UPN2_111,19,33792480,T,C,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn281Asp/c.841A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),7499,404,7913,"0,0510552256",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,844",Tolerated,"31,45","31,41"
"inspected, not in 2nd illumina, not in 454",UPN2_006,19,33792509,G,A,missense_variant(MODERATE|MISSENSE|gCg/gTg|p.Ala271Val/c.812C>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),0,91,91,1,1,1,1,1,1,1,1,1,8,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,"0,257",Tolerated,0,"33,87"
"low bq, low freq, many artifacts",UPN2_045,19,33792525,T,A,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser266Cys/c.796A>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),2274,27,2308,"0,0116984402",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,19",Neutral,"0,01",Damaging,"33,59","18,44"
"low bq, low freq, many artifacts, many samples",UPN2_043,19,33792542,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His260Pro/c.779A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1172,21,1208,"0,017384106",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,91,Tolerated,"33,72","23,19"
"low bq, many samples",UPN2_045,19,33792542,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His260Pro/c.779A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2323,60,2408,"0,0249169435",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,91,Tolerated,"33,02","20,13"
"low bq, low freq, many artifacts, many samples",UPN2_050,19,33792542,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His260Pro/c.779A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1732,36,1783,"0,0201906898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,91,Tolerated,"33,55","19,03"
"low bq, many samples",UPN2_051,19,33792542,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His260Pro/c.779A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),749,24,782,"0,0306905371",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,91,Tolerated,"33,12","19,71"
"low bq, many samples",UPN2_052,19,33792542,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His260Pro/c.779A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1506,40,1556,"0,0257069409",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,91,Tolerated,"33,3","17,83"
low bq,UPN2_053,19,33792542,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His260Pro/c.779A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1358,40,1411,"0,0283486889",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,91,Tolerated,"33,7","20,33"
"low bq, low freq, many artifacts",UPN2_041,19,33792546,C,T,missense_variant(MODERATE|MISSENSE|Gcg/Acg|p.Ala259Thr/c.775G>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),1184,20,1206,"0,0165837479",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,71",Neutral,727,Tolerated,"30,88","25,2"
"low bq, low freq, many artifacts",UPN2_041,19,33792552,C,T,missense_variant(MODERATE|MISSENSE|Ggc/Agc|p.Gly257Ser/c.769G>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),1176,30,1207,"0,0248550124",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,1",Neutral,"0,874",Tolerated,"33,35","26,87"
"low bq, low freq, many artifacts, many samples",UPN2_043,19,33792560,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys254Met/c.761A>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),2328,27,2363,"0,0114261532",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,83",Neutral,6,Damaging,"31,7","16,59"
"low bq, low freq, many artifacts, many samples",UPN2_045,19,33792560,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys254Met/c.761A>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),4561,57,4642,"0,01227919",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,83",Neutral,6,Damaging,"31,77","16,37"
"low bq, low freq, many artifacts, many samples",UPN2_050,19,33792560,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys254Met/c.761A>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),3426,36,3483,"0,0103359173",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,83",Neutral,6,Damaging,"31,72","17,5"
"low bq, low freq, many artifacts, many samples",UPN2_052,19,33792560,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys254Met/c.761A>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),2962,39,3009,"0,0129611167",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,83",Neutral,6,Damaging,"32,03","19,49"
"low bq, low freq, many artifacts",UPN2_053,19,33792560,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys254Met/c.761A>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),2672,29,2713,"0,0106892739",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,83",Neutral,6,Damaging,"31,48","18,59"
"low bq, bad alignment, low freq, many artifacts",UPN2_043,19,33792563,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu253Arg/c.758T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2331,25,2363,"0,0105797715",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,98",Neutral,38,Damaging,"25,88","15,92"
"inspected, bad alignment, many artifacts",UPN2_049,19,33792564,G,A,missense_variant(MODERATE|MISSENSE|Ctc/Ttc|p.Leu253Phe/c.757C>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),197,28,225,"0,1244444444",0,1,0,0,1,1,0,1,4,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,"0,008",Damaging,"32,89","29,57"
"low freq, many artifacts",UPN2_043,19,33792566,G,A,missense_variant(MODERATE|MISSENSE|gCg/gTg|p.Ala252Val/c.755C>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),2332,25,2363,"0,0105797715",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,"0,211",Tolerated,"32,99",32
"inspected, many artifacts",UPN2_047,19,33792596,C,A,missense_variant(MODERATE|MISSENSE|gGt/gTt|p.Gly242Val/c.725G>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),479,20,500,"0,04",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,"0,368",Tolerated,"31,94","33,05"
inspected,UPN2_044,19,33792624,G,A,missense_variant(MODERATE|MISSENSE|Ccc/Tcc|p.Pro233Ser/c.697C>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),46,23,69,"0,3333333333",1,1,1,1,1,0,1,1,7,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,32",Deleterious,"0,096",Tolerated,"35,54","35,83"
inspected,UPN2_041,19,33792624,G,T,missense_variant(MODERATE|MISSENSE|Ccc/Acc|p.Pro233Thr/c.697C>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),577,27,607,"0,0444810544",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,66",Deleterious,"0,001",Damaging,"35,06","31,48"
"inspected, strandbias",UPN2_041,19,33792638,G,A,missense_variant(MODERATE|MISSENSE|cCg/cTg|p.Pro228Leu/c.683C>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),1127,29,1157,"0,0250648228",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,96",Deleterious,0,Damaging,"32,09","30,72"
"inspected, strandbias",UPN2_041,19,33792640,CG,C,frameshift_variant(HIGH||ccg/|p.Pro227fs/c.680delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1124,29,1159,"0,0250215703",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,23",NA
inspected,UPN2_044,19,33792645,TG,T,frameshift_variant(HIGH||ccc/|p.Thr226fs/c.675delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),320,30,350,"0,0857142857",0,1,0,1,0,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,07",NA
"inspected, many artifacts",UPN2_041,19,33792669,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met218Leu/c.652A>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),1131,27,1160,"0,0232758621",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,23",Neutral,"0,006",Damaging,"35,22","35,19"
"low bq, many samples",UPN2_015,19,33792719,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu201Gln/c.602T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),368,44,415,"0,1060240964",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,03",Neutral,739,Tolerated,"29,78","15,11"
"low bq, many samples",UPN2_021,19,33792719,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu201Gln/c.602T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),592,21,614,"0,0342019544",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,03",Neutral,739,Tolerated,"30,27","18,43"
"low bq, many samples",UPN2_022,19,33792719,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu201Gln/c.602T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),802,27,831,"0,0324909747",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,03",Neutral,739,Tolerated,"30,52","14,74"
"low bq, many samples",UPN2_041,19,33792719,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu201Gln/c.602T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),1037,39,1085,"0,0359447005",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,03",Neutral,739,Tolerated,"28,97","16,97"
"low bq, many samples",UPN2_027,19,33792719,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu201Gln/c.602T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),834,20,856,"0,023364486",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,03",Neutral,739,Tolerated,"30,46","19,6"
"low bq, many samples",UPN2_046,19,33792719,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu201Gln/c.602T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),787,30,821,"0,0365408039",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,03",Neutral,739,Tolerated,"29,25","15,87"
"low bq, many samples",UPN2_047,19,33792719,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu201Gln/c.602T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),880,37,919,"0,0402611534",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,03",Neutral,739,Tolerated,"29,08","15,3"
"low bq, many samples",UPN2_048,19,33792719,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu201Gln/c.602T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),742,34,776,"0,043814433",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,03",Neutral,739,Tolerated,"29,08","16,62"
"low bq, many samples",UPN2_049,19,33792719,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu201Gln/c.602T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),438,23,468,"0,0491452991",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,03",Neutral,739,Tolerated,"28,73","16,52"
"low bq, many samples",UPN2_050,19,33792719,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu201Gln/c.602T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),592,20,614,"0,0325732899",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,03",Neutral,739,Tolerated,"29,14","16,95"
"low bq, many samples",UPN2_037,19,33792719,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu201Gln/c.602T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),475,27,502,"0,0537848606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,03",Neutral,739,Tolerated,"30,93","16,59"
"low bq, many samples",UPN2_038,19,33792719,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu201Gln/c.602T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),947,31,984,"0,031504065",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,03",Neutral,739,Tolerated,"30,6","16,48"
"low bq, many samples",UPN2_053,19,33792719,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu201Gln/c.602T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),459,21,483,"0,0434782609",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,03",Neutral,739,Tolerated,"29,74",14
"low bq, many samples",UPN2_008,19,33792719,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu201Gln/c.602T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),956,29,988,"0,0293522267",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,03",Neutral,739,Tolerated,"30,5","14,9"
"low bq, many samples",UPN2_055,19,33792719,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu201Gln/c.602T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),419,24,443,"0,0541760722",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,03",Neutral,739,Tolerated,"29,07","16,29"
"low bq, many samples",UPN2_058,19,33792719,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu201Gln/c.602T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),611,27,640,"0,0421875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,03",Neutral,739,Tolerated,"29,16","18,04"
low bq,UPN2_040,19,33792719,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu201Gln/c.602T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),96,22,120,"0,1833333333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,03",Neutral,739,Tolerated,"30,02","15,27"
"low bq, many samples",UPN2_041,19,33792737,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His195Pro/c.584A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1056,33,1092,"0,0302197802",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,3",Neutral,173,Tolerated,"28,77","14,21"
"low bq, many samples",UPN2_046,19,33792737,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His195Pro/c.584A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),795,20,815,"0,0245398773",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,3",Neutral,173,Tolerated,"28,61","14,65"
"low bq, many samples",UPN2_047,19,33792737,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His195Pro/c.584A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),890,27,920,"0,0293478261",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,3",Neutral,173,Tolerated,"29,42","14,93"
"low bq, many samples",UPN2_038,19,33792737,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His195Pro/c.584A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),947,23,979,"0,0234933606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,3",Neutral,173,Tolerated,"29,39","15,09"
low bq,UPN2_008,19,33792737,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His195Pro/c.584A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),961,29,991,"0,0292633703",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,3",Neutral,173,Tolerated,"29,03","14,24"
"low bq, many samples",UPN2_041,19,33792743,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His193Pro/c.578A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1061,27,1092,"0,0247252747",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,93",Neutral,101,Tolerated,"28,89",14
"low bq, many samples",UPN2_046,19,33792743,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His193Pro/c.578A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),789,25,815,"0,0306748466",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,93",Neutral,101,Tolerated,"28,85","14,88"
"low bq, many samples",UPN2_047,19,33792743,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His193Pro/c.578A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),892,23,920,"0,025",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,93",Neutral,101,Tolerated,"29,28","15,13"
"low bq, many samples",UPN2_008,19,33792743,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His193Pro/c.578A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),960,26,991,"0,0262361251",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,93",Neutral,101,Tolerated,"29,32",14
low bq,UPN2_058,19,33792743,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His193Pro/c.578A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),624,22,652,"0,0337423313",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,93",Neutral,101,Tolerated,"28,62","14,82"
"inspected, many artifacts",UPN2_048,19,33792749,T,C,missense_variant(MODERATE|MISSENSE|cAc/cGc|p.His191Arg/c.572A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),743,20,782,"0,0255754476",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,4",Neutral,"0,054",Tolerated,"29,23",33
"low bq, low freq, many artifacts, many samples",UPN2_041,19,33792749,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His191Pro/c.572A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1063,23,1092,"0,0210622711",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,08",Neutral,71,Tolerated,"28,88","14,78"
"low bq, many samples",UPN2_046,19,33792749,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His191Pro/c.572A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),787,27,815,"0,0331288344",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,08",Neutral,71,Tolerated,"29,13","14,67"
"low bq, many samples",UPN2_047,19,33792749,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His191Pro/c.572A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),895,21,920,"0,022826087",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,08",Neutral,71,Tolerated,"29,51","14,86"
"low bq, many samples",UPN2_050,19,33792749,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His191Pro/c.572A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),603,20,625,"0,032",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,08",Neutral,71,Tolerated,"29,34","14,9"
"low bq, many samples",UPN2_008,19,33792749,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His191Pro/c.572A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),964,23,991,"0,0232088799",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,08",Neutral,71,Tolerated,"29,23",14
low bq,UPN2_058,19,33792749,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His191Pro/c.572A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),624,27,654,"0,0412844037",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,08",Neutral,71,Tolerated,"29,02","16,3"
"many samples, GGC repeat",UPN2_021,19,33792754,GGGC,G,disruptive_inframe_deletion(MODERATE||ccgccc/ccc|p.Pro189del/c.564_566delGCC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),587,28,617,"0,0453808752",0,0,0,1,0,0,0,1,2,"3,0928",NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,"-0,97",Neutral,NA,NA,"34,66",NA
"many samples, GGC repeat",UPN2_022,19,33792754,GGGC,G,disruptive_inframe_deletion(MODERATE||ccgccc/ccc|p.Pro189del/c.564_566delGCC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),784,37,823,"0,0449574727",0,0,0,1,0,0,0,1,2,"3,0928",NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,"-0,97",Neutral,NA,NA,"34,56",NA
"many samples, GGC repeat",UPN2_023,19,33792754,GGGC,G,disruptive_inframe_deletion(MODERATE||ccgccc/ccc|p.Pro189del/c.564_566delGCC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),561,29,591,"0,0490693739",1,0,0,1,0,0,0,1,3,"3,0928",NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,"-0,97",Neutral,NA,NA,"34,69",NA
"many samples, GGC repeat",UPN2_041,19,33792754,GGGC,G,disruptive_inframe_deletion(MODERATE||ccgccc/ccc|p.Pro189del/c.564_566delGCC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1040,45,1091,"0,0412465628",1,0,0,1,0,0,0,1,3,"3,0928",NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,"-0,97",Neutral,NA,NA,"34,37",NA
"many samples, GGC repeat",UPN2_026,19,33792754,GGGC,G,disruptive_inframe_deletion(MODERATE||ccgccc/ccc|p.Pro189del/c.564_566delGCC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),610,28,638,"0,0438871473",1,0,0,1,0,0,0,1,3,"3,0928",NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,"-0,97",Neutral,NA,NA,"34,83",NA
"many samples, GGC repeat",UPN2_027,19,33792754,GGGC,G,disruptive_inframe_deletion(MODERATE||ccgccc/ccc|p.Pro189del/c.564_566delGCC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),804,52,860,"0,0604651163",1,0,0,1,0,0,0,1,3,"3,0928",NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,"-0,97",Neutral,NA,NA,"34,75",NA
"many samples, GGC repeat",UPN2_042,19,33792754,GGGC,G,disruptive_inframe_deletion(MODERATE||ccgccc/ccc|p.Pro189del/c.564_566delGCC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),384,20,404,"0,0495049505",1,0,0,1,0,0,0,1,3,"3,0928",NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,"-0,97",Neutral,NA,NA,"33,98",NA
"many samples, GGC repeat",UPN2_028,19,33792754,GGGC,G,disruptive_inframe_deletion(MODERATE||ccgccc/ccc|p.Pro189del/c.564_566delGCC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),426,26,453,"0,0573951435",0,0,0,1,0,0,0,1,2,"3,0928",NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,"-0,97",Neutral,NA,NA,"34,41",NA
"many samples, GGC repeat",UPN2_044,19,33792754,GGGC,G,disruptive_inframe_deletion(MODERATE||ccgccc/ccc|p.Pro189del/c.564_566delGCC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),484,41,532,"0,0770676692",0,1,0,1,0,1,0,1,4,"3,0928",NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,"-0,97",Neutral,NA,NA,"34,7",NA
"many samples, GGC repeat",UPN2_029,19,33792754,GGGC,G,disruptive_inframe_deletion(MODERATE||ccgccc/ccc|p.Pro189del/c.564_566delGCC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),350,20,370,"0,0540540541",0,0,0,1,0,0,0,1,2,"3,0928",NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,"-0,97",Neutral,NA,NA,"34,96",NA
"many samples, GGC repeat",UPN2_030,19,33792754,GGGC,G,disruptive_inframe_deletion(MODERATE||ccgccc/ccc|p.Pro189del/c.564_566delGCC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),402,20,422,"0,0473933649",1,0,0,1,0,0,0,1,3,"3,0928",NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,"-0,97",Neutral,NA,NA,"33,97",NA
"many samples, GGC repeat",UPN2_032,19,33792754,GGGC,G,disruptive_inframe_deletion(MODERATE||ccgccc/ccc|p.Pro189del/c.564_566delGCC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),162,20,184,"0,1086956522",1,1,0,1,0,1,0,1,5,"3,0928",NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,"-0,97",Neutral,NA,NA,"34,99",NA
"many samples, GGC repeat",UPN2_046,19,33792754,GGGC,G,disruptive_inframe_deletion(MODERATE||ccgccc/ccc|p.Pro189del/c.564_566delGCC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),748,58,816,"0,0710784314",1,0,0,1,0,1,0,1,4,"3,0928",NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,"-0,97",Neutral,NA,NA,"34,01",NA
"many samples, GGC repeat",UPN2_047,19,33792754,GGGC,G,disruptive_inframe_deletion(MODERATE||ccgccc/ccc|p.Pro189del/c.564_566delGCC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),885,32,920,"0,0347826087",1,0,0,1,0,0,0,1,3,"3,0928",NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,"-0,97",Neutral,NA,NA,"34,48",NA
"many samples, GGC repeat",UPN2_048,19,33792754,GGGC,G,disruptive_inframe_deletion(MODERATE||ccgccc/ccc|p.Pro189del/c.564_566delGCC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),750,32,782,"0,0409207161",1,0,0,1,0,0,0,1,3,"3,0928",NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,"-0,97",Neutral,NA,NA,"34,52",NA
"many samples, GGC repeat",UPN2_036,19,33792754,GGGC,G,disruptive_inframe_deletion(MODERATE||ccgccc/ccc|p.Pro189del/c.564_566delGCC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),634,24,658,"0,0364741641",1,0,0,1,0,0,0,1,3,"3,0928",NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,"-0,97",Neutral,NA,NA,"34,61",NA
"many samples, GGC repeat",UPN2_050,19,33792754,GGGC,G,disruptive_inframe_deletion(MODERATE||ccgccc/ccc|p.Pro189del/c.564_566delGCC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),586,30,625,"0,048",0,0,0,1,0,0,0,1,2,"3,0928",NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,"-0,97",Neutral,NA,NA,"34,12",NA
"many samples, GGC repeat",UPN2_037,19,33792754,GGGC,G,disruptive_inframe_deletion(MODERATE||ccgccc/ccc|p.Pro189del/c.564_566delGCC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),480,20,500,"0,04",0,0,0,1,0,0,0,1,2,"3,0928",NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,"-0,97",Neutral,NA,NA,"34,53",NA
"many samples, GGC repeat",UPN2_051,19,33792754,GGGC,G,disruptive_inframe_deletion(MODERATE||ccgccc/ccc|p.Pro189del/c.564_566delGCC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),329,23,354,"0,0649717514",1,0,0,1,0,0,0,1,3,"3,0928",NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,"-0,97",Neutral,NA,NA,"34,41",NA
"many samples, GGC repeat",UPN2_052,19,33792754,GGGC,G,disruptive_inframe_deletion(MODERATE||ccgccc/ccc|p.Pro189del/c.564_566delGCC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),439,37,478,"0,0774058577",1,1,0,1,0,1,0,1,5,"3,0928",NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,"-0,97",Neutral,NA,NA,"34,76",NA
"many samples, GGC repeat",UPN2_038,19,33792754,GGGC,G,disruptive_inframe_deletion(MODERATE||ccgccc/ccc|p.Pro189del/c.564_566delGCC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),933,41,979,"0,0418794688",0,0,0,1,0,0,0,1,2,"3,0928",NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,"-0,97",Neutral,NA,NA,"34,7",NA
"many samples, GGC repeat",UPN2_053,19,33792754,GGGC,G,disruptive_inframe_deletion(MODERATE||ccgccc/ccc|p.Pro189del/c.564_566delGCC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),459,24,484,"0,0495867769",0,0,0,1,0,0,0,1,2,"3,0928",NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,"-0,97",Neutral,NA,NA,"34,42",NA
"many samples, GGC repeat",UPN2_008,19,33792754,GGGC,G,disruptive_inframe_deletion(MODERATE||ccgccc/ccc|p.Pro189del/c.564_566delGCC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),928,53,991,"0,053481332",0,0,0,1,0,0,0,1,2,"3,0928",NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,"-0,97",Neutral,NA,NA,"34,95",NA
"many samples, GGC repeat",UPN2_009,19,33792754,GGGC,G,disruptive_inframe_deletion(MODERATE||ccgccc/ccc|p.Pro189del/c.564_566delGCC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),531,22,558,"0,0394265233",1,0,0,1,0,0,0,1,3,"3,0928",NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,"-0,97",Neutral,NA,NA,"34,94",NA
"many samples, GGC repeat",UPN2_055,19,33792754,GGGC,G,disruptive_inframe_deletion(MODERATE||ccgccc/ccc|p.Pro189del/c.564_566delGCC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),416,29,448,"0,0647321429",1,0,0,1,0,0,0,1,3,"3,0928",NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,"-0,97",Neutral,NA,NA,"34,31",NA
"many samples, GGC repeat",UPN2_058,19,33792754,GGGC,G,disruptive_inframe_deletion(MODERATE||ccgccc/ccc|p.Pro189del/c.564_566delGCC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),621,28,656,"0,0426829268",0,0,0,1,0,0,0,1,2,"3,0928",NO,NO,NA,NA,NO,NO,NO,NA,NO,NO,"-0,97",Neutral,NA,NA,"34,58",NA
"inspected, many artifacts",UPN2_038,19,33792773,G,T,missense_variant(MODERATE|MISSENSE|cCg/cAg|p.Pro183Gln/c.548C>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),960,28,988,"0,028340081",0,0,0,0,0,1,0,1,2,NO,NO,COSM5065106,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,"0,034",Damaging,"32,29",29
"low bq, many samples",UPN2_041,19,33792779,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr181Ser/c.542A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1057,28,1088,"0,0257352941",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,43,Damaging,"28,08",14
"low bq, many samples",UPN2_046,19,33792779,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr181Ser/c.542A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),797,21,820,"0,0256097561",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,43,Damaging,"27,97","14,86"
"low bq, many samples",UPN2_047,19,33792779,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr181Ser/c.542A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),890,27,919,"0,0293797606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,43,Damaging,"27,76","14,48"
low bq,UPN2_048,19,33792779,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr181Ser/c.542A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),756,22,781,"0,0281690141",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,43,Damaging,"27,6","15,18"
"low bq, many samples",UPN2_014,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),475,118,599,"0,1969949917",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"27,81","14,64"
"low bq, many samples",UPN2_015,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),268,39,312,"0,125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"30,79","14,33"
"low bq, many samples",UPN2_016,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),247,51,300,"0,17",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"28,1","14,71"
"low bq, many samples",UPN2_017,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),101,21,122,"0,1721311475",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"27,8","14,33"
"low bq, many samples",UPN2_018,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),141,35,179,"0,1955307263",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"28,67","14,2"
"low bq, many samples",UPN2_019,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),307,82,394,"0,2081218274",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"27,93","14,82"
"low bq, many samples",UPN2_020,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),231,62,302,"0,2052980132",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"27,89","14,4"
"low bq, many samples",UPN2_021,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),477,122,610,"0,2",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"27,57","14,63"
"low bq, bad alignment, many samples",UPN2_002,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),200,26,229,"0,1135371179",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"26,33","15,88"
"low bq, many samples",UPN2_022,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),668,145,819,"0,177045177",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"27,71","15,47"
"low bq, bad alignment, many samples",UPN2_023,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),471,111,587,"0,1890971039",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"26,97","14,76"
"low bq, many samples",UPN2_041,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),872,190,1075,"0,176744186",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"27,66","15,52"
"low bq, many samples",UPN2_024,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),90,20,111,"0,1801801802",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"27,62",14
"low bq, many samples",UPN2_025,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),366,87,456,"0,1907894737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"28,03","15,2"
"low bq, many samples",UPN2_026,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),496,123,631,"0,1949286846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"27,71","15,23"
"low bq, many samples",UPN2_027,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),672,163,848,"0,1922169811",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"27,69","14,93"
"low bq, many samples, no database",UPN2_089,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),40,26,67,"0,3880597015",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,"0,037",Damaging,"33,15",18
"low bq, many samples",UPN2_042,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),302,73,396,"0,1843434343",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"28,04","14,84"
"low bq, many samples",UPN2_028,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),354,82,444,"0,1846846847",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"27,63","15,98"
"low bq, many samples",UPN2_043,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),221,46,268,"0,171641791",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"27,44","15,93"
"low bq, many samples",UPN2_044,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),402,71,481,"0,1476091476",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"28,1","14,87"
"low bq, many samples",UPN2_029,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),300,66,373,"0,1769436997",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"27,6","15,83"
"low bq, many samples",UPN2_030,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),341,67,421,"0,1591448931",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"27,38","15,25"
"low bq, many samples",UPN2_031,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),138,36,177,"0,2033898305",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"27,77","15,25"
"low bq, many samples",UPN2_045,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),238,65,311,"0,2090032154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"27,61","14,6"
"low bq, many samples",UPN2_032,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),148,31,182,"0,1703296703",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"28,09","14,94"
"low bq, many samples",UPN2_046,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),634,159,811,"0,196054254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"28,1","15,47"
"low bq, many samples",UPN2_033,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),386,70,460,"0,152173913",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"27,03","15,59"
"low bq, many samples",UPN2_034,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),130,26,159,"0,1635220126",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"28,48","15,38"
"low bq, many samples",UPN2_047,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),725,160,901,"0,1775804661",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"27,47","15,93"
"low bq, many samples",UPN2_048,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),623,140,775,"0,1806451613",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"27,26","15,8"
"low bq, many samples",UPN2_035,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),332,83,419,"0,1980906921",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"27,66","14,94"
"low bq, many samples",UPN2_036,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),494,140,649,"0,2157164869",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"28,02","14,99"
"low bq, many samples",UPN2_049,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),372,84,463,"0,181425486",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"27,19","16,19"
"low bq, many samples",UPN2_050,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),487,117,617,"0,1896272285",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"27,55","14,75"
"low bq, many samples",UPN2_037,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),401,90,498,"0,1807228916",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"27,77","14,71"
"low bq, many samples",UPN2_051,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),294,59,356,"0,1657303371",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"27,83","16,41"
"low bq, many samples",UPN2_052,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),382,77,465,"0,1655913978",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"27,53","15,6"
"low bq, many samples",UPN2_038,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),783,179,971,"0,184346035",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"27,58","15,46"
"low bq, many samples",UPN2_039,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),288,50,343,"0,1457725948",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"27,84","14,4"
"low bq, bad alignment, many samples",UPN2_053,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),377,90,475,"0,1894736842",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"26,97","15,43"
"low bq, many samples",UPN2_054,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),288,63,356,"0,1769662921",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"27,91","16,05"
"low bq, bad alignment, many samples",UPN2_007,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),340,55,401,"0,1371571072",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"26,87","14,73"
"low bq, bad alignment, many samples",UPN2_008,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),819,139,977,"0,142272262",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"26,95","15,15"
"low bq, many samples",UPN2_009,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),473,78,560,"0,1392857143",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"27,13","15,03"
"low bq, many samples",UPN2_010,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),165,31,199,"0,1557788945",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"27,62","14,71"
"low bq, many samples",UPN2_055,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),379,67,451,"0,1485587583",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"27,69","15,6"
"low bq, many samples",UPN2_056,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),194,26,224,"0,1160714286",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"28,46","16,23"
"low bq, many samples",UPN2_090,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),76,44,120,"0,3666666667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"29,76","17,23"
"low bq, bad alignment, many samples",UPN2_057,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),247,46,305,"0,1508196721",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"26,93","14,15"
"low bq, many samples",UPN2_058,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),525,113,650,"0,1738461538",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"27,46","15,06"
"low bq, bad alignment, many samples",UPN2_012,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),165,24,196,"0,1224489796",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"26,66",16
low bq,UPN2_013,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),115,21,140,"0,15",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,37,Damaging,"27,04","16,1"
"low bq, many samples, no database",UPN2_107,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),38,36,74,"0,4864864865",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,"0,037",Damaging,"34,13","16,92"
"low bq, many samples, no database",UPN2_108,19,33792788,A,C,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu178Arg/c.533T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),40,27,67,"0,4029850746",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,"0,037",Damaging,"32,38","16,44"
"low freq, many artifacts",UPN2_050,19,33792823,CT,C,frameshift_variant(HIGH||gag/|p.Glu166fs/c.497delA|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1587,27,1652,"0,0163438257",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,11",NA
"low freq, many artifacts",UPN2_041,19,33792824,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu166Ala/c.497A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1242,23,1270,"0,0181102362",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,98",Neutral,132,Tolerated,"34,97","34,7"
"inspected, low coverage, problematic area",UPN2_011,19,33792837,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln162Lys/c.484C>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),78,55,133,"0,4135338346",1,1,1,0,1,0,1,1,6,NA,NA,NO,NO,NO,NA,NA,NO,NO,NO,NO,"-1,09",Neutral,"0,002",Damaging,"35,24","35,53"
"inspected, many artifacts",UPN2_050,19,33792840,T,C,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys161Glu/c.481A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1610,20,1654,"0,0120918984",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,0,Damaging,"35,03","34,7"
"inspected, many artifacts, strandbias",UPN2_044,19,33792847,CA,C,frameshift_variant(HIGH||ctg/|p.Leu158fs/c.473delT|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),447,26,474,"0,0548523207",0,0,0,1,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,72",NA
"many samples, no database",UPN2_014,19,33792863,G,C,missense_variant(MODERATE|MISSENSE|cCg/cGg|p.Pro153Arg/c.458C>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),269,33,302,"0,1092715232",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,066",Tolerated,"31,89","31,67"
many samples,UPN2_015,19,33792863,G,C,missense_variant(MODERATE|MISSENSE|cCg/cGg|p.Pro153Arg/c.458C>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),199,22,221,"0,0995475113",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,66,Tolerated,"31,84",32
"many samples, no database",UPN2_019,19,33792863,G,C,missense_variant(MODERATE|MISSENSE|cCg/cGg|p.Pro153Arg/c.458C>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),168,21,190,"0,1105263158",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,066",Tolerated,32,"31,14"
"many samples, no database",UPN2_021,19,33792863,G,C,missense_variant(MODERATE|MISSENSE|cCg/cGg|p.Pro153Arg/c.458C>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),255,31,286,"0,1083916084",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,066",Tolerated,"31,62",32
many samples,UPN2_022,19,33792863,G,C,missense_variant(MODERATE|MISSENSE|cCg/cGg|p.Pro153Arg/c.458C>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),362,40,405,"0,0987654321",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,66,Tolerated,"31,54","30,83"
"low freq, many artifacts, many samples",UPN2_041,19,33792863,G,C,missense_variant(MODERATE|MISSENSE|cCg/cGg|p.Pro153Arg/c.458C>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1229,23,1263,"0,0182106097",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,66,Tolerated,"33,55","29,65"
"many samples, no database",UPN2_025,19,33792863,G,C,missense_variant(MODERATE|MISSENSE|cCg/cGg|p.Pro153Arg/c.458C>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),199,27,228,"0,1184210526",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,066",Tolerated,"31,54",32
"many samples, no database",UPN2_026,19,33792863,G,C,missense_variant(MODERATE|MISSENSE|cCg/cGg|p.Pro153Arg/c.458C>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),290,36,327,"0,1100917431",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,066",Tolerated,"31,8","31,19"
many samples,UPN2_027,19,33792863,G,C,missense_variant(MODERATE|MISSENSE|cCg/cGg|p.Pro153Arg/c.458C>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),412,40,452,"0,0884955752",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,66,Tolerated,"31,91","31,27"
many samples,UPN2_044,19,33792863,G,C,missense_variant(MODERATE|MISSENSE|cCg/cGg|p.Pro153Arg/c.458C>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),444,23,468,"0,0491452991",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,66,Tolerated,"33,43","30,74"
"many samples, no database",UPN2_029,19,33792863,G,C,missense_variant(MODERATE|MISSENSE|cCg/cGg|p.Pro153Arg/c.458C>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),157,24,181,"0,1325966851",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,066",Tolerated,"31,82","31,25"
many samples,UPN2_046,19,33792863,G,C,missense_variant(MODERATE|MISSENSE|cCg/cGg|p.Pro153Arg/c.458C>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),422,28,451,"0,0620842572",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,66,Tolerated,"31,81","31,61"
many samples,UPN2_033,19,33792863,G,C,missense_variant(MODERATE|MISSENSE|cCg/cGg|p.Pro153Arg/c.458C>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),233,24,257,"0,093385214",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,66,Tolerated,"32,51","31,25"
many samples,UPN2_047,19,33792863,G,C,missense_variant(MODERATE|MISSENSE|cCg/cGg|p.Pro153Arg/c.458C>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),449,39,489,"0,0797546012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,66,Tolerated,"32,07","31,72"
many samples,UPN2_048,19,33792863,G,C,missense_variant(MODERATE|MISSENSE|cCg/cGg|p.Pro153Arg/c.458C>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),353,28,384,"0,0729166667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,66,Tolerated,"31,35","31,21"
many samples,UPN2_036,19,33792863,G,C,missense_variant(MODERATE|MISSENSE|cCg/cGg|p.Pro153Arg/c.458C>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),361,35,398,"0,0879396985",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,66,Tolerated,"32,48","31,54"
"many samples, no database",UPN2_037,19,33792863,G,C,missense_variant(MODERATE|MISSENSE|cCg/cGg|p.Pro153Arg/c.458C>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),313,37,351,"0,1054131054",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,066",Tolerated,"33,12","31,22"
"many samples, no database",UPN2_038,19,33792863,G,C,missense_variant(MODERATE|MISSENSE|cCg/cGg|p.Pro153Arg/c.458C>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),454,54,508,"0,1062992126",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,066",Tolerated,"32,03","31,59"
"many samples, no database",UPN2_008,19,33792863,G,C,missense_variant(MODERATE|MISSENSE|cCg/cGg|p.Pro153Arg/c.458C>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),410,65,477,"0,1362683438",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,066",Tolerated,"31,58","31,22"
many samples,UPN2_009,19,33792863,G,C,missense_variant(MODERATE|MISSENSE|cCg/cGg|p.Pro153Arg/c.458C>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),251,23,275,"0,0836363636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,66,Tolerated,"31,7",32
"inspected, low freq, neutral effect",UPN2_058,19,33792863,G,C,missense_variant(MODERATE|MISSENSE|cCg/cGg|p.Pro153Arg/c.458C>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),994,28,1028,"0,0272373541",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,66,Tolerated,"33,58","31,21"
"inspected, many artifacts",UPN2_041,19,33792915,C,T,missense_variant(MODERATE|MISSENSE|Gcc/Acc|p.Ala136Thr/c.406G>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),707,21,728,"0,0288461538",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,"0,541",Tolerated,"34,11","32,67"
"inspected, bad alignment, many artifacts",UPN2_041,19,33792938,G,A,missense_variant(MODERATE|MISSENSE|cCg/cTg|p.Pro128Leu/c.383C>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),1416,46,1468,"0,0313351499",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,48",Neutral,"0,026",Damaging,31,"30,11"
"inspected, bad alignment, many artifacts",UPN2_051,19,33792938,G,A,missense_variant(MODERATE|MISSENSE|cCg/cTg|p.Pro128Leu/c.383C>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),1272,20,1300,"0,0153846154",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,48",Neutral,"0,026",Damaging,"31,18","29,95"
inspected,UPN2_044,19,33792945,C,A,missense_variant(MODERATE|MISSENSE|Ggg/Tgg|p.Gly126Trp/c.376G>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),384,59,445,"0,1325842697",0,1,0,0,1,1,0,1,4,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,28",Neutral,"0,145",Tolerated,"30,8","27,86"
"low bq, bad alignment, many samples",UPN2_041,19,33792947,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His125Pro/c.374A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1405,53,1467,"0,0361281527",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,69,Tolerated,"23,77",14
"low bq, bad alignment, many samples",UPN2_042,19,33792947,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His125Pro/c.374A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),611,27,642,"0,0420560748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,69,Tolerated,"24,51",14
"low bq, bad alignment, many samples",UPN2_043,19,33792947,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His125Pro/c.374A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),856,32,897,"0,0356744705",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,69,Tolerated,"23,8","14,62"
"low bq, bad alignment, many samples",UPN2_045,19,33792947,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His125Pro/c.374A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),854,26,885,"0,0293785311",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,69,Tolerated,"23,44","14,5"
"low bq, bad alignment, many samples",UPN2_050,19,33792947,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His125Pro/c.374A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2575,95,2687,"0,035355415",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,69,Tolerated,"23,98","14,84"
"low bq, bad alignment, many samples",UPN2_051,19,33792947,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His125Pro/c.374A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1250,38,1300,"0,0292307692",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,69,Tolerated,"23,83",14
"low bq, bad alignment, many samples",UPN2_052,19,33792947,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His125Pro/c.374A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1986,81,2084,"0,0388675624",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,69,Tolerated,24,"14,57"
"low bq, bad alignment, many samples",UPN2_053,19,33792947,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His125Pro/c.374A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1121,36,1167,"0,030848329",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,69,Tolerated,"23,34",14
"low bq, bad alignment, many samples",UPN2_054,19,33792947,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His125Pro/c.374A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1113,28,1150,"0,0243478261",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,69,Tolerated,"23,93","15,43"
"low bq, bad alignment, many samples",UPN2_057,19,33792947,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His125Pro/c.374A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1098,43,1148,"0,037456446",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,69,Tolerated,"24,11","14,47"
"low bq, bad alignment",UPN2_058,19,33792947,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His125Pro/c.374A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1364,54,1424,"0,0379213483",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,69,Tolerated,"23,65","14,61"
"inspected, bad alignment, many artifacts",UPN2_041,19,33792950,G,A,missense_variant(MODERATE|MISSENSE|gCg/gTg|p.Ala124Val/c.371C>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),1422,45,1467,"0,0306748466",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,14",Neutral,"0,121",Tolerated,"33,04","32,13"
inspected,UPN2_056,19,33792957,C,A,missense_variant(MODERATE|MISSENSE|Ggg/Tgg|p.Gly122Trp/c.364G>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),53,26,79,"0,3291139241",1,1,1,1,1,1,1,1,8,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,"0,01",Damaging,"31,19","28,62"
"inspected, many artifacts",UPN2_052,19,33792960,G,A,missense_variant(MODERATE|MISSENSE|Ccc/Tcc|p.Pro121Ser/c.361C>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),2039,32,2072,"0,0154440154",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,51",Neutral,"0,324",Tolerated,"31,74","31,69"
"inspected, bad alignment, many artifacts",UPN2_058,19,33792961,C,A,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met120Ile/c.360G>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),1385,32,1417,"0,0225829217",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,267",Tolerated,"33,27","32,59"
"inspected, many artifacts",UPN2_041,19,33792961,C,T,missense_variant(MODERATE|MISSENSE|atG/atA|p.Met120Ile/c.360G>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),1437,20,1459,"0,0137080192",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,267",Tolerated,"33,31","31,75"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,19,33792963,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met120Leu/c.358A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2630,32,2670,"0,0119850187",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,615,Tolerated,"26,73","14,22"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,19,33792963,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met120Leu/c.358A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2018,24,2068,"0,0116054159",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,615,Tolerated,"26,39",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_058,19,33792963,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met120Leu/c.358A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1382,22,1413,"0,0155697098",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,14",Neutral,615,Tolerated,"26,79","17,23"
"low bq, low freq, many artifacts, many samples",UPN2_050,19,33792965,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val119Gly/c.356T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1402,20,1432,"0,0139664804",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,4",Neutral,475,Tolerated,"29,93","15,65"
"low bq, many samples",UPN2_041,19,33792969,C,T,missense_variant(MODERATE|MISSENSE|Gcc/Acc|p.Ala118Thr/c.352G>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),709,32,741,"0,0431848853",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,191,Tolerated,"34,71","18,16"
inspected,UPN2_044,19,33792987,G,A,missense_variant(MODERATE|MISSENSE|Ccc/Tcc|p.Pro112Ser/c.334C>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),198,25,224,"0,1116071429",0,1,0,0,1,0,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,63",Neutral,"0,206",Tolerated,"34,92","34,8"
"inspected, CGC repeat, many samples",UPN2_050,19,33793007,TCGC,T,disruptive_inframe_deletion(MODERATE||ggcgac/gac|p.Gly104del/c.311_313delGCG|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),1334,20,1356,"0,0147492625",1,0,0,1,0,0,0,1,3,"0,1827",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,45",Neutral,NA,NA,"35,07",NA
"inspected, CGC repeat, many samples",UPN2_052,19,33793007,TCGC,T,disruptive_inframe_deletion(MODERATE||ggcgac/gac|p.Gly104del/c.311_313delGCG|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),1028,20,1053,"0,0189933523",0,0,0,1,0,0,0,1,2,"0,1827",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,45",Neutral,NA,NA,"35,19",NA
"CGC repeat, many samples",UPN2_058,19,33793007,TCGC,T,disruptive_inframe_deletion(MODERATE||ggcgac/gac|p.Gly104del/c.311_313delGCG|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),691,23,718,"0,0320334262",1,0,0,1,0,0,0,1,3,"0,1827",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,45",Neutral,NA,NA,"34,91",NA
"low freq, many artifacts, many samples",UPN2_048,19,33793037,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val95Glu/c.284T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),1776,29,1813,"0,0159955874",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,44",Neutral,866,Tolerated,"30,39",32
"low freq, bad alignment, many artifacts",UPN2_048,19,33793050,C,T,missense_variant(MODERATE|MISSENSE|Gcc/Acc|p.Ala91Thr/c.271G>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),1792,21,1813,"0,0115830116",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,271",Tolerated,"34,49","34,57"
"low freq, bad alignment, many artifacts",UPN2_048,19,33793075,G,T,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe82Leu/c.246C>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),1765,46,1813,"0,0253723111",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,0,Damaging,"35,58","34,39"
"low freq, bad alignment, many artifacts",UPN2_048,19,33793092,A,G,missense_variant(MODERATE|MISSENSE|Ttc/Ctc|p.Phe77Leu/c.229T>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1774,24,1807,"0,0132816823",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,96",Neutral,"0,596",Tolerated,"24,17",34
"inspected, many artifacts",UPN2_046,19,33793096,G,T,missense_variant(MODERATE|MISSENSE|gaC/gaA|p.Asp75Glu/c.225C>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),1234,22,1260,"0,0174603175",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,"0,348",Tolerated,"35,28","31,09"
inspected,UPN2_057,19,33793110,C,T,missense_variant(MODERATE|MISSENSE|Gcc/Acc|p.Ala71Thr/c.211G>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),785,29,815,"0,0355828221",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,"0,007",Damaging,"33,59","32,1"
"inspected, many artifacts",UPN2_047,19,33793112,G,A,missense_variant(MODERATE|MISSENSE|cCg/cTg|p.Pro70Leu/c.209C>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),2072,25,2103,"0,0118877794",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,61",Deleterious,"0,001",Damaging,"35,32","32,16"
"inspected, many artifacts",UPN2_048,19,33793127,C,A,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser65Ile/c.194G>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),1759,22,1784,"0,0123318386",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,0,Damaging,"32,84","30,77"
"inspected, many artifacts",UPN2_053,19,33793127,C,T,missense_variant(MODERATE|MISSENSE|aGc/aAc|p.Ser65Asn/c.194G>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),1663,20,1685,"0,0118694362",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"33,02","30,85"
inspected,UPN2_044,19,33793133,T,A,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp63Val/c.188A>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),309,24,336,"0,0714285714",0,0,0,1,1,0,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,22",Deleterious,0,Damaging,"33,76","27,17"
"low bq, bad alignment, many samples",UPN2_001,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),596,42,650,"0,0646153846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"25,65","14,43"
"low bq, bad alignment, many samples",UPN2_014,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1982,87,2165,"0,0401847575",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"24,95",14
"low bq, bad alignment, many samples",UPN2_015,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3012,120,3282,"0,0365630713",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"25,08","14,26"
"low bq, bad alignment, many samples",UPN2_016,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1279,44,1371,"0,0320933625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"24,52","14,16"
"low bq, bad alignment, many samples",UPN2_017,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),720,22,781,"0,0281690141",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"24,62",14
"low bq, bad alignment, many samples",UPN2_018,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1291,54,1410,"0,0382978723",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"24,99","14,13"
"low bq, bad alignment, many samples",UPN2_019,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1420,55,1519,"0,0362080316",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"24,91","14,13"
"low bq, bad alignment, many samples",UPN2_020,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1014,37,1109,"0,0333633904",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"24,67",14
"low bq, bad alignment, many samples",UPN2_021,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1700,61,1852,"0,032937365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"25,23",14
"low bq, bad alignment, many samples",UPN2_002,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),593,39,644,"0,0605590062",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"25,74",14
"low bq, bad alignment, many samples",UPN2_022,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1684,66,1830,"0,0360655738",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"24,67","14,21"
"low bq, bad alignment, many samples",UPN2_023,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2303,93,2507,"0,0370961308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"24,73",14
"low bq, bad alignment, many samples",UPN2_041,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3611,105,4014,"0,0261584454",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"25,63","14,55"
"low bq, bad alignment, many samples",UPN2_024,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),803,27,866,"0,0311778291",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"25,16",14
"low bq, bad alignment, many samples",UPN2_025,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2248,96,2447,"0,0392317123",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"24,89",14
"low bq, bad alignment, many samples",UPN2_026,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2219,74,2405,"0,0307692308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"24,99",14
"low bq, bad alignment, many samples",UPN2_027,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2424,101,2612,"0,0386676876",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"24,91",14
"low bq, bad alignment, many samples",UPN2_089,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),874,28,942,"0,0297239915",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"24,73","14,25"
"low bq, bad alignment, many samples",UPN2_042,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2533,78,2817,"0,0276890309",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"25,87","14,83"
"low bq, bad alignment, many samples",UPN2_028,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1509,62,1624,"0,0381773399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"24,79",14
"low bq, bad alignment, many samples",UPN2_043,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1635,45,1838,"0,0244831338",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"26,18",14
"low bq, bad alignment, many samples",UPN2_029,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1548,61,1673,"0,0364614465",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"24,98","14,41"
"low bq, bad alignment, many samples",UPN2_030,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1961,79,2121,"0,0372465818",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"24,81",14
"low bq, bad alignment, many samples",UPN2_031,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1185,53,1285,"0,0412451362",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"24,95",14
"low bq, bad alignment, many samples",UPN2_045,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2194,68,2420,"0,0280991736",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"25,73",14
"low bq, bad alignment, many samples",UPN2_046,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2098,61,2363,"0,0258146424",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"25,83","14,64"
"low bq, bad alignment, many samples",UPN2_033,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1498,52,1619,"0,0321185917",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,25,"14,13"
"low bq, bad alignment, many samples",UPN2_047,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3616,101,3972,"0,025427996",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"25,72",14
"low bq, bad alignment, many samples",UPN2_048,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3078,102,3386,"0,0301240402",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"25,65","14,56"
"low bq, bad alignment, many samples",UPN2_035,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1349,61,1464,"0,0416666667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"24,79","14,36"
"low bq, bad alignment, many samples",UPN2_036,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2809,105,3017,"0,0348027842",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"24,85","14,25"
"low bq, bad alignment, many samples",UPN2_006,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),376,24,410,"0,0585365854",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,25,14
"low bq, bad alignment, many samples",UPN2_049,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1511,43,1686,"0,0255041518",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"26,1","14,51"
"low bq, bad alignment, many samples",UPN2_050,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2426,62,2697,"0,0229885057",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"25,84","14,23"
"low bq, bad alignment, many samples",UPN2_037,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3651,121,3939,"0,0307184565",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"24,85","14,11"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1990,46,2190,"0,0210045662",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"25,4","14,15"
"low bq, bad alignment, many samples",UPN2_052,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1679,44,1862,"0,0236305048",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"25,74","14,3"
"low bq, bad alignment, many samples",UPN2_038,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4062,172,4401,"0,0390820268",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"24,81","14,19"
"low bq, bad alignment, many samples",UPN2_039,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1418,64,1528,"0,0418848168",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"25,01",14
"low bq, bad alignment, many samples",UPN2_053,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2857,93,3155,"0,0294770206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"25,69","14,43"
"low bq, bad alignment, many samples",UPN2_054,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1322,55,1490,"0,0369127517",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"25,98",14
"low bq, bad alignment, many samples",UPN2_007,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1768,87,1930,"0,0450777202",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"25,56","14,08"
"low bq, bad alignment, many samples",UPN2_008,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2741,130,2962,"0,043889264",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"25,49","14,1"
"low bq, bad alignment, many samples",UPN2_009,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1984,120,2173,"0,0552231937",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"25,33",14
"low bq, bad alignment, many samples",UPN2_010,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1029,57,1120,"0,0508928571",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"25,32",14
"low bq, bad alignment, many samples",UPN2_011,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),827,45,904,"0,0497787611",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"25,52","14,4"
"low bq, bad alignment, many samples",UPN2_055,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2622,78,2908,"0,0268225585",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"25,85","14,23"
"low bq, bad alignment, many samples",UPN2_090,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1296,40,1368,"0,0292397661",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"25,79","14,18"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1394,31,1531,"0,0202482038",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"25,84",14
"low bq, bad alignment, many samples",UPN2_058,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3584,99,4011,"0,0246821242",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"25,89","14,22"
"low bq, bad alignment, many samples",UPN2_012,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),655,35,708,"0,0494350282",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"25,19",14
"low bq, bad alignment, many samples",UPN2_040,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),672,24,738,"0,0325203252",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"24,54",14
"low bq, bad alignment, many samples",UPN2_013,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),577,27,624,"0,0432692308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"25,17",14
"low bq, bad alignment, many samples",UPN2_091,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1152,44,1230,"0,0357723577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"24,66",14
"low bq, bad alignment, many samples",UPN2_093,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),503,31,545,"0,0568807339",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"25,2",14
"low bq, bad alignment, many samples",UPN2_081,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),177,23,207,"0,1111111111",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"24,62",14
"low bq, bad alignment, many samples",UPN2_094,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1389,52,1482,"0,0350877193",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"25,05","14,25"
"low bq, bad alignment, many samples",UPN2_095,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1033,44,1106,"0,0397830018",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"24,91",14
"low bq, bad alignment, many samples",UPN2_096,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1247,57,1340,"0,0425373134",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"24,93","14,12"
"low bq, bad alignment, many samples",UPN2_097,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1568,70,1692,"0,0413711584",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"24,98","14,1"
"low bq, bad alignment, many samples",UPN2_098,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),739,44,817,"0,0538555692",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"24,96","14,59"
"low bq, bad alignment, many samples",UPN2_099,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),764,33,818,"0,0403422983",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"24,76","14,21"
"low bq, bad alignment, many samples",UPN2_100,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),887,37,948,"0,0390295359",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"24,63",14
"low bq, bad alignment, many samples",UPN2_101,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),935,28,991,"0,0282542886",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"24,6",14
"low bq, bad alignment, many samples",UPN2_102,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1103,45,1185,"0,0379746835",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"24,89","14,29"
"low bq, bad alignment, many samples",UPN2_103,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),925,46,997,"0,0461384152",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"25,14","14,28"
"low bq, bad alignment, many samples",UPN2_104,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1269,59,1385,"0,042599278",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"24,99","14,22"
"low bq, bad alignment, many samples",UPN2_105,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),702,41,764,"0,0536649215",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"24,93","14,61"
"low bq, bad alignment, many samples",UPN2_106,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1359,67,1473,"0,0454854039",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"24,9","14,19"
"low bq, bad alignment, many samples",UPN2_107,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2164,84,2325,"0,0361290323",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"24,8",14
"low bq, bad alignment, many samples",UPN2_108,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2081,82,2218,"0,0369702435",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"24,71","14,16"
"low bq, bad alignment, many samples",UPN2_109,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1437,65,1545,"0,0420711974",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"24,96","14,2"
"low bq, bad alignment, many samples",UPN2_110,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1448,63,1555,"0,0405144695",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"24,99","14,11"
"low bq, bad alignment",UPN2_111,19,33793157,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile55Ser/c.164T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1156,46,1252,"0,0367412141",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,1,Damaging,"24,96",14
"low bq, bad alignment, many samples",UPN2_044,19,33793157,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),576,52,646,"0,080495356",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,62",Deleterious,1,Damaging,"25,36","15,44"
"low bq, bad alignment, many samples",UPN2_032,19,33793157,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),729,33,781,"0,0422535211",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,62",Deleterious,1,Damaging,"25,05","15,09"
"low bq, bad alignment, many samples",UPN2_034,19,33793157,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),444,21,477,"0,0440251572",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,62",Deleterious,1,Damaging,"25,84","14,33"
"low bq, bad alignment",UPN2_056,19,33793157,A,T,missense_variant(MODERATE|MISSENSE|aTc/aAc|p.Ile55Asn/c.164T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),914,69,998,"0,0691382766",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,62",Deleterious,1,Damaging,"26,45","15,06"
"low bq, bad alignment, many samples",UPN2_001,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),618,35,659,"0,0531107739",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"26,58","14,63"
"low bq, bad alignment, many samples",UPN2_014,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2079,85,2173,"0,0391164289",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"26,78",14
"low bq, bad alignment, many samples",UPN2_015,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3173,120,3308,"0,0362756953",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"26,69","14,18"
"low bq, bad alignment, many samples",UPN2_016,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1316,68,1387,"0,0490266763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"26,63",14
"low bq, many samples",UPN2_017,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),738,45,788,"0,057106599",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,28",14
"low bq, bad alignment, many samples",UPN2_018,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1348,64,1423,"0,0449754041",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"26,85","14,34"
"low bq, many samples",UPN2_019,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1454,70,1532,"0,045691906",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,09","14,54"
"low bq, bad alignment, many samples",UPN2_020,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1054,50,1116,"0,0448028674",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"26,71","15,16"
"low bq, bad alignment, many samples",UPN2_021,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1757,105,1869,"0,0561797753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"26,9","14,21"
"low bq, bad alignment, many samples",UPN2_002,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),616,25,645,"0,0387596899",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"26,55",14
"low bq, bad alignment, many samples",UPN2_022,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1740,99,1849,"0,0535424554",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"26,87","14,4"
"low bq, bad alignment, many samples",UPN2_023,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2383,131,2530,"0,0517786561",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"26,86","14,21"
"low bq, many samples",UPN2_041,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3853,187,4056,"0,0461045365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,77","14,48"
"low bq, bad alignment, many samples",UPN2_024,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),834,37,874,"0,0423340961",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"26,97","14,35"
"low bq, bad alignment, many samples",UPN2_025,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2343,99,2459,"0,0402602684",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"26,75","14,42"
"low bq, bad alignment, many samples",UPN2_026,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2303,116,2431,"0,0477169889",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"26,86","14,17"
"low bq, bad alignment, many samples",UPN2_027,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2487,127,2628,"0,048325723",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"26,87","14,17"
"low bq, many samples",UPN2_089,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),910,36,946,"0,0380549683",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,8","14,72"
"low bq, many samples",UPN2_042,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2710,132,2848,"0,0463483146",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,75","14,2"
"low bq, many samples",UPN2_028,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1549,82,1642,"0,0499390987",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,03","14,09"
"low bq, many samples",UPN2_043,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1744,99,1856,"0,0533405172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,81","14,28"
"low bq, many samples",UPN2_044,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),622,22,646,"0,0340557276",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,44",14
"low bq, bad alignment, many samples",UPN2_029,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1611,90,1706,"0,0527549824",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"26,82","14,22"
"low bq, bad alignment, many samples",UPN2_030,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2034,96,2138,"0,0449017774",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"26,71","14,27"
"low bq, bad alignment, many samples",UPN2_031,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1243,49,1296,"0,037808642",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"26,9","14,14"
"low bq, many samples",UPN2_045,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2306,113,2437,"0,0463684858",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,75","14,12"
"low bq, bad alignment, many samples",UPN2_032,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),749,30,783,"0,0383141762",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"26,8",14
"low bq, many samples",UPN2_046,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2275,101,2378,"0,0424726661",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,7","14,13"
"low bq, bad alignment, many samples",UPN2_033,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1556,80,1641,"0,0487507617",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"26,64","14,09"
"low bq, many samples",UPN2_034,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),456,26,482,"0,0539419087",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,44",14
"low bq, many samples",UPN2_047,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3803,178,4003,"0,04446665",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,71","14,29"
"low bq, many samples",UPN2_048,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3232,150,3391,"0,044234739",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,82","14,22"
"low bq, bad alignment, many samples",UPN2_035,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1397,74,1477,"0,0501015572",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"26,78",14
"low bq, bad alignment, many samples",UPN2_036,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2905,171,3084,"0,0554474708",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"26,96","14,19"
"low bq, many samples",UPN2_049,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1614,81,1709,"0,0473961381",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,69","14,65"
"low bq, many samples",UPN2_050,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2568,126,2708,"0,0465288035",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,53","14,37"
"low bq, bad alignment, many samples",UPN2_037,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3774,180,3967,"0,0453743383",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"26,68","14,22"
"low bq, many samples",UPN2_051,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2080,114,2205,"0,0517006803",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,65","14,33"
"low bq, many samples",UPN2_052,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1783,91,1881,"0,0483785221",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,77","14,14"
"low bq, bad alignment, many samples",UPN2_038,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4221,182,4423,"0,0411485417",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"26,78","14,39"
"low bq, many samples",UPN2_039,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1465,120,1596,"0,0751879699",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,03","14,15"
"low bq, many samples",UPN2_053,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3025,138,3185,"0,0433281005",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,59","14,33"
"low bq, many samples",UPN2_054,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1422,70,1496,"0,0467914439",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"28,02","14,1"
"low bq, bad alignment, many samples",UPN2_007,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1838,88,1945,"0,0452442159",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"26,87",14
"low bq, bad alignment, many samples",UPN2_008,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2843,122,2981,"0,0409258638",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"26,82","14,62"
"low bq, bad alignment, many samples",UPN2_009,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2086,100,2195,"0,0455580866",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"26,86","14,22"
"low bq, bad alignment, many samples",UPN2_010,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1070,63,1139,"0,0553116769",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"26,98","14,21"
"low bq, bad alignment, many samples",UPN2_011,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),881,38,924,"0,0411255411",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"26,79",14
"low bq, many samples",UPN2_055,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2780,147,2944,"0,0499320652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,64","14,18"
"low bq, many samples",UPN2_056,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),948,56,1015,"0,0551724138",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,7","14,45"
"low bq, many samples",UPN2_090,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1327,58,1394,"0,0416068867",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"28,06","15,28"
"low bq, many samples",UPN2_057,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1463,72,1539,"0,0467836257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,71","14,1"
"low bq, many samples",UPN2_058,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3839,166,4044,"0,0410484669",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,8","14,63"
"low bq, bad alignment, many samples",UPN2_012,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),690,27,722,"0,0373961219",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"26,86","14,48"
"low bq, bad alignment, many samples",UPN2_040,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),712,32,745,"0,0429530201",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"26,69",14
"low bq, bad alignment, many samples",UPN2_013,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),599,30,630,"0,0476190476",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"26,85","14,23"
"low bq, many samples",UPN2_091,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1180,55,1237,"0,0444624091",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,7","14,76"
"low bq, many samples",UPN2_094,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1435,51,1487,"0,0342972428",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,5","14,25"
"low bq, many samples",UPN2_095,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1072,40,1112,"0,035971223",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,39","14,5"
"low bq, many samples",UPN2_096,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1303,34,1342,"0,0253353204",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,66",14
"low bq, many samples",UPN2_097,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1647,49,1701,"0,0288065844",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,7","14,29"
"low bq, many samples",UPN2_098,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),790,33,823,"0,0400972053",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,38","14,67"
"low bq, many samples",UPN2_099,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),789,28,822,"0,0340632603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,65","15,25"
"low bq, many samples",UPN2_100,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),918,33,951,"0,0347003155",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,77","15,33"
"low bq, many samples",UPN2_101,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),958,33,996,"0,0331325301",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,71","14,39"
"low bq, many samples",UPN2_102,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1139,50,1195,"0,0418410042",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,96","15,06"
"low bq, many samples",UPN2_103,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),969,34,1003,"0,0338983051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,46","14,21"
"low bq, many samples",UPN2_104,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1352,43,1397,"0,0307802434",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,36","14,16"
"low bq, many samples",UPN2_105,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),736,28,770,"0,0363636364",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,5","14,25"
"low bq, many samples",UPN2_106,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1433,48,1482,"0,032388664",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,7","14,15"
"low bq, many samples",UPN2_107,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2269,57,2328,"0,0244845361",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,79","14,46"
"low bq, many samples",UPN2_108,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2154,73,2231,"0,032720753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,68","14,4"
"low bq, many samples",UPN2_109,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1497,63,1562,"0,0403329065",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,78","14,68"
"low bq, many samples",UPN2_110,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1509,48,1565,"0,0306709265",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,72",14
low bq,UPN2_111,19,33793158,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile55Leu/c.163A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1224,36,1263,"0,0285035629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,276,Tolerated,"27,63",14
"low bq, bad alignment, many samples",UPN2_001,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),622,39,677,"0,0576070901",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"22,52","14,33"
"low bq, bad alignment, many samples",UPN2_014,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2096,69,2219,"0,0310950879",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"22,5","14,9"
"low bq, bad alignment, many samples",UPN2_015,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3193,125,3407,"0,0366891694",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"22,58",14
"low bq, bad alignment, many samples",UPN2_016,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1316,50,1420,"0,0352112676",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"22,73","14,62"
"low bq, bad alignment, many samples",UPN2_017,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),744,31,810,"0,0382716049",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"23,04",14
"low bq, bad alignment, many samples",UPN2_018,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1374,43,1460,"0,0294520548",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"22,56","14,3"
"low bq, bad alignment, many samples",UPN2_019,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1471,56,1578,"0,0354879594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"22,76","14,12"
"low bq, bad alignment, many samples",UPN2_020,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1058,51,1135,"0,0449339207",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"22,76","14,35"
"low bq, bad alignment, many samples",UPN2_021,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1804,76,1923,"0,0395215809",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"22,46","14,09"
"low bq, bad alignment, many samples",UPN2_002,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),584,51,655,"0,0778625954",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"22,01","14,35"
"low bq, bad alignment, many samples",UPN2_022,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1768,67,1886,"0,0355249205",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"22,4","14,19"
"low bq, bad alignment, many samples",UPN2_023,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2410,96,2584,"0,0371517028",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"22,6","14,07"
"low bq, bad alignment, many samples",UPN2_041,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3808,154,4153,"0,0370816277",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"23,69",14
"low bq, bad alignment, many samples",UPN2_024,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),837,27,893,"0,0302351624",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"23,48",14
"low bq, bad alignment, many samples",UPN2_025,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2379,92,2529,"0,036378015",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"22,64","14,14"
"low bq, bad alignment, many samples",UPN2_026,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2342,77,2508,"0,0307017544",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"22,49","14,4"
"low bq, bad alignment, many samples",UPN2_027,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2524,101,2690,"0,0375464684",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"22,75",14
"low bq, bad alignment, many samples",UPN2_042,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2648,128,2917,"0,0438806993",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"23,65","14,14"
"low bq, bad alignment, many samples",UPN2_028,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1595,63,1695,"0,0371681416",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"22,5","14,62"
"low bq, bad alignment, many samples",UPN2_043,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1718,95,1898,"0,050052687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"24,07",14
"low bq, bad alignment, many samples",UPN2_044,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),611,24,658,"0,0364741641",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"22,91",14
"low bq, bad alignment, many samples",UPN2_029,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1642,72,1752,"0,0410958904",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"22,71","14,68"
"low bq, bad alignment, many samples",UPN2_030,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2050,80,2191,"0,0365130078",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"22,6",14
"low bq, bad alignment, many samples",UPN2_031,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1254,54,1335,"0,0404494382",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"22,9",14
"low bq, bad alignment, many samples",UPN2_045,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2287,109,2497,"0,0436523829",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"23,62",14
"low bq, bad alignment, many samples",UPN2_032,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),755,27,803,"0,0336239103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,23,14
"low bq, bad alignment, many samples",UPN2_046,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2247,86,2452,"0,0350734095",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"23,26",14
"low bq, bad alignment, many samples",UPN2_033,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1566,55,1679,"0,0327575938",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,23,"14,4"
"low bq, bad alignment, many samples",UPN2_047,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3769,164,4089,"0,0401076058",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"23,71","14,31"
"low bq, bad alignment, many samples",UPN2_048,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3180,135,3480,"0,0387931034",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"23,66",14
"low bq, bad alignment, many samples",UPN2_035,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1414,42,1514,"0,0277410832",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"22,56",14
"low bq, bad alignment, many samples",UPN2_036,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2962,119,3175,"0,037480315",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"22,7","14,34"
"low bq, bad alignment, many samples",UPN2_006,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),377,29,419,"0,0692124105",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"22,16",14
"low bq, bad alignment, many samples",UPN2_049,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1618,79,1760,"0,0448863636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"23,72",14
"low bq, bad alignment, many samples",UPN2_050,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2557,125,2796,"0,0447067239",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"23,46","14,32"
"low bq, bad alignment, many samples",UPN2_037,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3807,159,4071,"0,0390567428",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"22,65","14,08"
"low bq, bad alignment, many samples",UPN2_051,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2076,87,2251,"0,0386494891",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"23,67","14,59"
"low bq, bad alignment, many samples",UPN2_052,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1783,87,1943,"0,0447761194",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"23,33","14,15"
"low bq, bad alignment, many samples",UPN2_038,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4239,153,4528,"0,0337897527",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"22,71","14,45"
"low bq, bad alignment, many samples",UPN2_039,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1513,105,1661,"0,0632149308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"22,38",14
"low bq, bad alignment, many samples",UPN2_053,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3020,129,3273,"0,0394133822",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"23,48",14
"low bq, bad alignment, many samples",UPN2_054,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1395,84,1544,"0,0544041451",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"23,96",14
"low bq, bad alignment, many samples",UPN2_007,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1823,118,1991,"0,0592667002",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"22,73","14,37"
"low bq, bad alignment, many samples",UPN2_008,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2783,184,3041,"0,0605064124",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"22,38","14,23"
"low bq, bad alignment, many samples",UPN2_009,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2060,150,2254,"0,0665483585",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"22,51","14,05"
"low bq, bad alignment, many samples",UPN2_010,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1075,62,1162,"0,0533562823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"22,11","14,4"
"low bq, bad alignment, many samples",UPN2_011,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),861,51,945,"0,053968254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"22,22","14,39"
"low bq, bad alignment, many samples",UPN2_055,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2746,134,3010,"0,0445182724",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"24,11","14,1"
"low bq, bad alignment, many samples",UPN2_056,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),948,44,1039,"0,0423484119",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"23,47",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_090,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1394,21,1427,"0,0147161878",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"25,2",14
"low bq, bad alignment, many samples",UPN2_057,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1443,76,1580,"0,0481012658",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"24,08","14,24"
"low bq, bad alignment, many samples",UPN2_058,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3833,150,4139,"0,0362406378",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"23,92","14,25"
"low bq, bad alignment, many samples",UPN2_012,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),666,57,737,"0,0773405699",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"22,81",14
"low bq, bad alignment, many samples",UPN2_040,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),712,29,763,"0,0380078637",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"22,78",14
"low bq, bad alignment, many samples",UPN2_013,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),582,43,642,"0,0669781931",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"22,86",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_091,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1221,27,1255,"0,0215139442",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"24,92",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_096,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1325,28,1367,"0,0204828091",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"25,25","14,25"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_097,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1687,23,1734,"0,0132641292",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"24,93",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_102,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1171,22,1209,"0,0181968569",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"25,18",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_103,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),989,21,1020,"0,0205882353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"24,44",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_104,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1386,25,1423,"0,0175685172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"24,54",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_107,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2314,31,2368,"0,0130912162",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"25,19","14,65"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_108,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2208,42,2273,"0,0184777827",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"25,04","14,17"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_109,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1539,28,1588,"0,0176322418",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"25,06",14
"low bq, bad alignment, low freq, many artifacts",UPN2_110,19,33793166,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu52Arg/c.155T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1559,32,1605,"0,0199376947",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,1,Damaging,"25,43",14
"low bq, low freq, many artifacts, many samples",UPN2_046,19,33793170,G,A,missense_variant(MODERATE|MISSENSE|Ccg/Tcg|p.Pro51Ser/c.151C>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),2434,25,2464,"0,0101461039",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,17",Neutral,34,Damaging,"33,83","23,12"
"low bq, low freq, many artifacts, many samples",UPN2_090,19,33793170,G,A,missense_variant(MODERATE|MISSENSE|Ccg/Tcg|p.Pro51Ser/c.151C>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),1408,21,1429,"0,0146955913",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,17",Neutral,34,Damaging,"33,56","24,38"
"low bq, bad alignment, many samples",UPN2_001,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),645,35,680,"0,0514705882",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"24,63","15,09"
"low bq, bad alignment, many samples",UPN2_014,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2147,77,2232,"0,0344982079",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"24,31",14
"low bq, bad alignment, many samples",UPN2_015,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3270,137,3417,"0,0400936494",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"24,24","14,2"
"low bq, bad alignment, many samples",UPN2_016,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1360,61,1428,"0,0427170868",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"23,99",14
"low bq, bad alignment, many samples",UPN2_017,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),780,29,814,"0,0356265356",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"24,13","14,69"
"low bq, bad alignment, many samples",UPN2_018,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1408,49,1466,"0,0334242838",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"24,14","14,27"
"low bq, bad alignment, many samples",UPN2_019,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1513,66,1586,"0,0416141236",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"24,48","14,2"
"low bq, bad alignment, many samples",UPN2_020,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1085,45,1144,"0,0393356643",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"24,34",14
"low bq, bad alignment, many samples",UPN2_021,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1847,78,1931,"0,0403935785",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"24,03",14
"low bq, bad alignment, many samples",UPN2_002,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),599,52,657,"0,0791476408",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"24,61",14
"low bq, bad alignment, many samples",UPN2_022,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1810,69,1889,"0,0365272631",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"24,03","14,19"
"low bq, bad alignment, many samples",UPN2_023,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2469,118,2599,"0,0454020777",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"24,3",14
"low bq, bad alignment, many samples",UPN2_041,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3936,235,4193,"0,0560457906",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"25,79","14,14"
"low bq, bad alignment, many samples",UPN2_024,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),856,37,893,"0,0414333707",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"24,41","14,19"
"low bq, bad alignment, many samples",UPN2_025,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2437,96,2539,"0,0378101615",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"24,24","14,21"
"low bq, bad alignment, many samples",UPN2_026,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2411,99,2516,"0,0393481717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"24,28","14,13"
"low bq, bad alignment, many samples",UPN2_027,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2576,112,2699,"0,0414968507",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"24,36","14,22"
"low bq, bad alignment, many samples",UPN2_089,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),919,40,964,"0,0414937759",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"26,11",14
"low bq, bad alignment, many samples",UPN2_042,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2722,195,2933,"0,0664848278",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"25,74","14,22"
"low bq, bad alignment, many samples",UPN2_028,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1616,81,1703,"0,0475631239",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"24,05",14
"low bq, bad alignment, many samples",UPN2_043,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1776,129,1910,"0,067539267",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"25,65","14,26"
"low bq, bad alignment, many samples",UPN2_044,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),621,45,666,"0,0675675676",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"25,44","14,29"
"low bq, bad alignment, many samples",UPN2_029,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1670,81,1761,"0,0459965928",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"24,2","14,09"
"low bq, bad alignment, many samples",UPN2_030,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2103,89,2199,"0,0404729422",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"24,53",14
"low bq, bad alignment, many samples",UPN2_031,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1284,52,1341,"0,0387770321",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"24,16",14
"low bq, bad alignment, many samples",UPN2_045,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2359,144,2511,"0,0573476703",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"25,64","14,27"
"low bq, bad alignment, many samples",UPN2_032,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),753,43,807,"0,053283767",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"24,5","14,16"
"low bq, bad alignment, many samples",UPN2_046,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2305,150,2465,"0,060851927",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"25,61","14,22"
"low bq, bad alignment, many samples",UPN2_033,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1616,57,1685,"0,0338278932",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"24,34","14,23"
"low bq, bad alignment, many samples",UPN2_034,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),469,26,497,"0,0523138833",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"24,76",14
"low bq, bad alignment, many samples",UPN2_047,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3834,256,4125,"0,0620606061",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"25,54","14,36"
"low bq, bad alignment, many samples",UPN2_048,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3270,218,3500,"0,0622857143",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"25,77","14,46"
"low bq, bad alignment, many samples",UPN2_035,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1441,67,1518,"0,0441370224",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"24,35",14
"low bq, bad alignment, many samples",UPN2_036,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3039,132,3188,"0,0414052698",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"24,2","14,26"
"low bq, bad alignment, many samples",UPN2_006,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),391,24,420,"0,0571428571",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"24,26",14
"low bq, bad alignment, many samples",UPN2_049,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1655,117,1775,"0,065915493",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"25,65","14,23"
"low bq, bad alignment, many samples",UPN2_050,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2616,194,2815,"0,0689165187",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"25,76","14,11"
"low bq, bad alignment, many samples",UPN2_037,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3890,173,4087,"0,0423293369",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"24,29","14,08"
"low bq, bad alignment, many samples",UPN2_051,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2127,128,2270,"0,0563876652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"25,4",14
"low bq, bad alignment, many samples",UPN2_052,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1827,128,1966,"0,0651068159",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"25,55","14,26"
"low bq, bad alignment, many samples",UPN2_038,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4339,192,4550,"0,0421978022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"24,26","14,51"
"low bq, bad alignment, many samples",UPN2_039,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1562,96,1666,"0,0576230492",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"23,92",14
"low bq, bad alignment, many samples",UPN2_053,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3099,192,3298,"0,0582171013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"25,72","14,17"
"low bq, bad alignment, many samples",UPN2_054,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1445,97,1558,"0,0622593068",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"25,65","14,21"
"low bq, bad alignment, many samples",UPN2_007,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1872,118,1999,"0,0590295148",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"24,89","14,11"
"low bq, bad alignment, many samples",UPN2_008,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2880,153,3053,"0,0501146413",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"24,64","14,12"
"low bq, bad alignment, many samples",UPN2_009,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2132,122,2265,"0,0538631347",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"24,54","14,06"
"low bq, bad alignment, many samples",UPN2_010,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1100,62,1165,"0,0532188841",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"24,48","14,42"
"low bq, bad alignment, many samples",UPN2_011,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),888,54,949,"0,0569020021",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"24,72","14,33"
"low bq, bad alignment, many samples",UPN2_055,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2819,189,3029,"0,0623968306",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"25,82","14,2"
"low bq, bad alignment, many samples",UPN2_056,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),970,70,1044,"0,0670498084",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"26,01","14,29"
"low bq, bad alignment, many samples",UPN2_090,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1370,55,1431,"0,0384346611",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"26,07",14
"low bq, bad alignment, many samples",UPN2_057,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1492,98,1595,"0,0614420063",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"25,38","14,2"
"low bq, bad alignment, many samples",UPN2_058,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3872,286,4174,"0,0685194058",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"25,88","14,37"
"low bq, bad alignment, many samples",UPN2_012,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),691,47,739,"0,0635994587",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"24,79","14,55"
"low bq, bad alignment, many samples",UPN2_040,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),734,33,767,"0,0430247718",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"24,12","14,21"
"low bq, bad alignment, many samples",UPN2_013,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),607,33,643,"0,0513219285",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"24,6","14,21"
"low bq, bad alignment, many samples",UPN2_091,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1198,51,1257,"0,0405727924",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"26,19","14,14"
"low bq, bad alignment, many samples",UPN2_081,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),197,24,223,"0,1076233184",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"24,73","15,04"
"low bq, bad alignment, many samples",UPN2_094,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1466,53,1519,"0,0348913759",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"25,87","14,38"
"low bq, bad alignment, many samples",UPN2_095,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1087,43,1132,"0,0379858657",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"26,13","14,3"
"low bq, bad alignment, many samples",UPN2_096,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1310,53,1369,"0,0387143901",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"26,26","14,38"
"low bq, bad alignment, many samples",UPN2_097,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1680,57,1738,"0,0327963176",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"25,83",14
"low bq, bad alignment, many samples",UPN2_098,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),804,34,839,"0,0405244338",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"26,12",14
"low bq, bad alignment, many samples",UPN2_099,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),808,33,843,"0,0391459075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"26,38","14,61"
"low bq, bad alignment, many samples",UPN2_100,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),923,48,973,"0,049331963",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"26,2",14
"low bq, bad alignment, many samples",UPN2_101,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),974,41,1019,"0,040235525",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"25,98","14,34"
"low bq, bad alignment, many samples",UPN2_102,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1150,53,1214,"0,0436573311",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"26,35","14,13"
"low bq, bad alignment, many samples",UPN2_103,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),986,33,1021,"0,0323212537",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"26,11","14,55"
"low bq, bad alignment, many samples",UPN2_104,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1368,56,1428,"0,0392156863",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"26,33","14,46"
"low bq, bad alignment, many samples",UPN2_105,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),757,35,792,"0,0441919192",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"25,94",14
"low bq, bad alignment, many samples",UPN2_106,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1463,62,1525,"0,0406557377",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"26,13","14,32"
"low bq, bad alignment, many samples",UPN2_107,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2287,82,2378,"0,0344827586",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"26,19","14,24"
"low bq, bad alignment, many samples",UPN2_108,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2179,92,2279,"0,0403685827",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"26,16","14,22"
"low bq, bad alignment, many samples",UPN2_109,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1529,62,1593,"0,0389202762",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"26,21","14,21"
"low bq, bad alignment, many samples",UPN2_110,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1562,51,1613,"0,0316181029",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"26,09",14
"low bq, bad alignment",UPN2_111,19,33793172,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu50Ala/c.149A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1223,59,1284,"0,0459501558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,07",Neutral,968,Tolerated,"26,41","14,34"
low bq,UPN2_057,19,33793173,C,T,missense_variant(MODERATE|MISSENSE|Gag/Aag|p.Glu50Lys/c.148G>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),1556,40,1607,"0,0248911014",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,104,Tolerated,"30,07","24,45"
"low bq, low freq, many artifacts, many samples",UPN2_050,19,33793179,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala48Pro/c.142G>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2781,29,2823,"0,0102727595",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,23",Neutral,36,Damaging,"30,1","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_051,19,33793179,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala48Pro/c.142G>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2245,25,2280,"0,0109649123",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,23",Neutral,36,Damaging,"30,09",14
"low bq, low freq, many artifacts, many samples",UPN2_055,19,33793179,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala48Pro/c.142G>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2990,40,3040,"0,0131578947",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,23",Neutral,36,Damaging,"30,63","14,45"
"low bq, low freq, many artifacts",UPN2_058,19,33793179,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala48Pro/c.142G>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4142,43,4191,"0,0102600811",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,23",Neutral,36,Damaging,"30,37","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_023,19,33793191,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala44Pro/c.130G>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1267,21,1289,"0,016291699",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,6,Damaging,"30,82",14
"low bq, low freq, many artifacts, many samples",UPN2_041,19,33793191,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala44Pro/c.130G>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2039,36,2081,"0,0172993753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,6,Damaging,"28,79",14
"low bq, low freq, many artifacts, many samples",UPN2_042,19,33793191,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala44Pro/c.130G>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1417,27,1449,"0,0186335404",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,6,Damaging,"29,07","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_045,19,33793191,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala44Pro/c.130G>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1224,24,1251,"0,0191846523",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,6,Damaging,"29,57","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_046,19,33793191,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala44Pro/c.130G>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1199,26,1226,"0,0212071778",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,6,Damaging,"28,68","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_047,19,33793191,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala44Pro/c.130G>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2024,33,2059,"0,0160271977",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,6,Damaging,"29,01",14
"low bq, low freq, many artifacts, many samples",UPN2_048,19,33793191,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala44Pro/c.130G>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1695,38,1738,"0,0218642117",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,6,Damaging,"28,86","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_050,19,33793191,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala44Pro/c.130G>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1375,25,1405,"0,0177935943",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,6,Damaging,"28,57","14,52"
"low bq, many samples",UPN2_051,19,33793191,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala44Pro/c.130G>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1098,27,1130,"0,0238938053",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,6,Damaging,"28,83",14
"low bq, low freq, many artifacts, many samples",UPN2_052,19,33793191,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala44Pro/c.130G>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),959,20,979,"0,0204290092",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,6,Damaging,"28,91","15,3"
"low bq, low freq, many artifacts, many samples",UPN2_038,19,33793191,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala44Pro/c.130G>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2234,28,2268,"0,012345679",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,6,Damaging,"30,87",14
"low bq, low freq, many artifacts, many samples",UPN2_053,19,33793191,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala44Pro/c.130G>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1611,26,1641,"0,0158439976",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,6,Damaging,"29,29",14
"low bq, many samples",UPN2_054,19,33793191,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala44Pro/c.130G>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),758,21,779,"0,026957638",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,6,Damaging,"28,8","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_055,19,33793191,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala44Pro/c.130G>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1471,32,1507,"0,0212342402",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,6,Damaging,"29,11",14
low bq,UPN2_058,19,33793191,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala44Pro/c.130G>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2031,46,2079,"0,0221260221",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,62",Neutral,6,Damaging,"28,86",14
"low bq, bad alignment, many samples",UPN2_001,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),307,27,339,"0,0796460177",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"16,1","14,26"
"low bq, bad alignment, many samples",UPN2_014,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1031,78,1115,"0,069955157",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"17,93","14,09"
"low bq, bad alignment, many samples",UPN2_016,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),649,55,712,"0,077247191",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"17,89","14,13"
"low bq, bad alignment, many samples",UPN2_017,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),372,29,402,"0,0721393035",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"17,5",14
"low bq, bad alignment, many samples",UPN2_018,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),679,50,734,"0,068119891",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"18,42",14
"low bq, bad alignment, many samples",UPN2_020,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),529,40,571,"0,0700525394",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"17,78",14
"low bq, bad alignment, many samples",UPN2_021,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),870,77,953,"0,0807974816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"17,78","14,26"
"low bq, bad alignment, many samples",UPN2_002,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),289,37,330,"0,1121212121",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"16,96",14
"low bq, bad alignment, many samples",UPN2_022,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),869,66,940,"0,070212766",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"17,9","14,47"
"low bq, bad alignment, many samples",UPN2_089,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),444,37,481,"0,0769230769",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"19,45","14,73"
"low bq, bad alignment, many samples",UPN2_028,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),779,54,843,"0,0640569395",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"17,97","14,78"
"low bq, bad alignment, many samples",UPN2_044,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),296,31,332,"0,093373494",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"17,35",14
"low bq, bad alignment, many samples",UPN2_029,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),801,69,877,"0,078677309",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"17,93","14,26"
"low bq, bad alignment, many samples",UPN2_031,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),620,52,674,"0,0771513353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"18,06","14,25"
"low bq, bad alignment, many samples",UPN2_045,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1109,138,1253,"0,1101356744",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"18,36","14,33"
"low bq, bad alignment, many samples",UPN2_032,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),359,37,400,"0,0925",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"17,99",14
"low bq, bad alignment, many samples",UPN2_033,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),769,65,840,"0,0773809524",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"18,12","14,28"
"low bq, bad alignment, many samples",UPN2_035,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),707,50,757,"0,0660501982",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"18,28","14,14"
"low bq, bad alignment, many samples",UPN2_049,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),788,85,881,"0,0964812713",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"18,17","14,31"
"low bq, bad alignment, many samples",UPN2_010,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),530,44,578,"0,0761245675",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"17,15","14,73"
"low bq, bad alignment, many samples",UPN2_011,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),428,43,475,"0,0905263158",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"17,21","14,16"
"low bq, bad alignment, many samples",UPN2_056,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),467,50,521,"0,0959692898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"18,08","14,5"
"low bq, bad alignment, many samples",UPN2_090,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),660,49,713,"0,0687237027",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"19,27","14,86"
"low bq, bad alignment, many samples",UPN2_057,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),710,92,807,"0,1140024783",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"18,66","14,14"
"low bq, bad alignment, many samples",UPN2_012,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),320,44,365,"0,1205479452",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"17,97","14,16"
"low bq, bad alignment, many samples",UPN2_040,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),346,32,383,"0,0835509138",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"17,77",14
"low bq, bad alignment, many samples",UPN2_013,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),290,29,320,"0,090625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"17,07",14
"low bq, bad alignment, many samples",UPN2_091,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),584,42,626,"0,0670926518",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"19,81","14,98"
"low bq, bad alignment, many samples",UPN2_094,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),710,46,759,"0,0606060606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"19,47","14,43"
"low bq, bad alignment, many samples",UPN2_095,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),526,40,567,"0,0705467372",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"19,07","14,35"
"low bq, bad alignment, many samples",UPN2_096,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),636,44,680,"0,0647058824",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"20,01","14,32"
"low bq, bad alignment, many samples",UPN2_097,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),798,61,862,"0,0707656613",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"19,03","14,23"
"low bq, bad alignment, many samples",UPN2_099,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),384,31,417,"0,0743405276",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"19,67","14,23"
"low bq, bad alignment, many samples",UPN2_100,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),455,27,485,"0,0556701031",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"19,45",14
"low bq, bad alignment, many samples",UPN2_101,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),479,28,508,"0,0551181102",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"19,73",14
"low bq, bad alignment, many samples",UPN2_102,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),554,46,603,"0,0762852405",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"19,74",14
"low bq, bad alignment, many samples",UPN2_103,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),470,40,510,"0,0784313725",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"19,2",14
"low bq, bad alignment, many samples",UPN2_104,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),667,44,711,"0,0618846695",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"19,35","14,5"
"low bq, bad alignment, many samples",UPN2_105,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),357,35,394,"0,0888324873",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"18,85","14,37"
"low bq, bad alignment, many samples",UPN2_106,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),715,46,762,"0,0603674541",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"19,44",14
"low bq, bad alignment, many samples",UPN2_107,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1109,72,1185,"0,0607594937",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"19,69","14,19"
"low bq, bad alignment, many samples",UPN2_108,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1056,70,1133,"0,0617828773",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"18,98","14,41"
"low bq, bad alignment, many samples",UPN2_109,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),753,39,796,"0,0489949749",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"19,59","14,18"
"low bq, bad alignment, many samples",UPN2_110,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),751,48,805,"0,0596273292",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"19,83","14,29"
"low bq, bad alignment",UPN2_111,19,33793199,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln41Pro/c.122A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),593,45,639,"0,0704225352",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,77",Neutral,"0,19",Tolerated,"19,18","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_041,19,33793203,C,G,missense_variant(MODERATE|MISSENSE|Gcg/Ccg|p.Ala40Pro/c.118G>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2047,36,2087,"0,0172496406",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,3",Neutral,215,Tolerated,30,"14,58"
"low bq, low freq, many artifacts, many samples",UPN2_042,19,33793203,C,G,missense_variant(MODERATE|MISSENSE|Gcg/Ccg|p.Ala40Pro/c.118G>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1422,31,1457,"0,0212765957",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,3",Neutral,215,Tolerated,"29,89",14
"low bq, many samples",UPN2_043,19,33793203,C,G,missense_variant(MODERATE|MISSENSE|Gcg/Ccg|p.Ala40Pro/c.118G>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),922,25,950,"0,0263157895",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,3",Neutral,215,Tolerated,"29,31","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_045,19,33793203,C,G,missense_variant(MODERATE|MISSENSE|Gcg/Ccg|p.Ala40Pro/c.118G>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1221,20,1256,"0,0159235669",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,3",Neutral,215,Tolerated,"29,75","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_047,19,33793203,C,G,missense_variant(MODERATE|MISSENSE|Gcg/Ccg|p.Ala40Pro/c.118G>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2031,32,2068,"0,0154738878",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,3",Neutral,215,Tolerated,"29,9",14
"low bq, low freq, many artifacts, many samples",UPN2_048,19,33793203,C,G,missense_variant(MODERATE|MISSENSE|Gcg/Ccg|p.Ala40Pro/c.118G>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1712,24,1742,"0,0137772675",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,3",Neutral,215,Tolerated,"30,23","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_050,19,33793203,C,G,missense_variant(MODERATE|MISSENSE|Gcg/Ccg|p.Ala40Pro/c.118G>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1376,27,1409,"0,0191625266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,3",Neutral,215,Tolerated,"29,9","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_037,19,33793203,C,G,missense_variant(MODERATE|MISSENSE|Gcg/Ccg|p.Ala40Pro/c.118G>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2028,26,2057,"0,0126397667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,3",Neutral,215,Tolerated,"31,07",14
"low bq, many samples",UPN2_051,19,33793203,C,G,missense_variant(MODERATE|MISSENSE|Gcg/Ccg|p.Ala40Pro/c.118G>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1100,26,1132,"0,0229681979",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,3",Neutral,215,Tolerated,"29,5",14
"low bq, low freq, many artifacts, many samples",UPN2_052,19,33793203,C,G,missense_variant(MODERATE|MISSENSE|Gcg/Ccg|p.Ala40Pro/c.118G>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),951,20,982,"0,0203665988",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,3",Neutral,215,Tolerated,"30,06",14
"low bq, low freq, many artifacts, many samples",UPN2_038,19,33793203,C,G,missense_variant(MODERATE|MISSENSE|Gcg/Ccg|p.Ala40Pro/c.118G>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2238,27,2271,"0,0118890357",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,3",Neutral,215,Tolerated,"31,2","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_053,19,33793203,C,G,missense_variant(MODERATE|MISSENSE|Gcg/Ccg|p.Ala40Pro/c.118G>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1614,29,1646,"0,017618469",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,3",Neutral,215,Tolerated,"30,31",14
"low bq, low freq, many artifacts, many samples",UPN2_055,19,33793203,C,G,missense_variant(MODERATE|MISSENSE|Gcg/Ccg|p.Ala40Pro/c.118G>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1469,27,1508,"0,0179045093",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,3",Neutral,215,Tolerated,"30,18",14
"low bq, low freq, many artifacts",UPN2_058,19,33793203,C,G,missense_variant(MODERATE|MISSENSE|Gcg/Ccg|p.Ala40Pro/c.118G>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2050,29,2084,"0,013915547",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,3",Neutral,215,Tolerated,"30,01","14,76"
"inspected, many artifacts",UPN2_041,19,33793209,C,G,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly38Arg/c.112G>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2053,39,2093,"0,0186335404",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,"0,007",Damaging,"33,02","30,49"
"low bq, low freq, many artifacts",UPN2_041,19,33793214,C,T,missense_variant(MODERATE|MISSENSE|gGc/gAc|p.Gly36Asp/c.107G>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),2051,33,2094,"0,0157593123",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,"6,30E-005",NO,NO,"-0,77",Neutral,89,Tolerated,"33,96","19,82"
"low bq, low freq, many artifacts, many samples",UPN2_041,19,33793222,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe33Leu/c.99T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),2048,23,2095,"0,0109785203",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,81",Neutral,247,Tolerated,"33,25","16,52"
"low bq, low freq, many artifacts, many samples",UPN2_048,19,33793222,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe33Leu/c.99T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),1720,20,1747,"0,0114481969",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,81",Neutral,247,Tolerated,"33,65","17,1"
"low bq, low freq, many artifacts, many samples",UPN2_041,19,33793223,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe33Tyr/c.98T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),2049,28,2095,"0,0133651551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,27",Neutral,1,Tolerated,"28,75","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_047,19,33793223,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe33Tyr/c.98T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),2025,26,2068,"0,0125725338",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,27",Neutral,1,Tolerated,"29,23","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_050,19,33793223,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe33Tyr/c.98T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),1375,21,1413,"0,0148619958",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,27",Neutral,1,Tolerated,"28,86",16
"low bq, low freq, many artifacts, many samples",UPN2_055,19,33793223,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe33Tyr/c.98T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),1483,22,1516,"0,0145118734",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,27",Neutral,1,Tolerated,"28,79","14,82"
"low bq, low freq, many artifacts",UPN2_058,19,33793223,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe33Tyr/c.98T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),2040,25,2087,"0,0119789171",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,27",Neutral,1,Tolerated,"29,01",15
"low freq, many artifacts, many samples",UPN2_015,19,33793224,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe33Val/c.97T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1661,28,1704,"0,0164319249",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-1,Neutral,28,Damaging,27,"15,04"
"low bq, low freq, many artifacts, many samples",UPN2_041,19,33793224,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe33Val/c.97T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2031,32,2095,"0,015274463",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-1,Neutral,28,Damaging,"27,85","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_047,19,33793224,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe33Val/c.97T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2017,24,2069,"0,0115998067",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-1,Neutral,28,Damaging,"28,22","14,92"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_036,19,33793224,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe33Val/c.97T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1537,26,1593,"0,0163214062",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-1,Neutral,28,Damaging,"26,93","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_050,19,33793224,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe33Val/c.97T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1353,30,1413,"0,0212314225",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-1,Neutral,28,Damaging,"28,38","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_037,19,33793224,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe33Val/c.97T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1999,25,2063,"0,0121182744",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-1,Neutral,28,Damaging,"27,39",14
"low bq, low freq, many artifacts, many samples",UPN2_038,19,33793224,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe33Val/c.97T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2225,29,2275,"0,0127472527",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-1,Neutral,28,Damaging,"27,38",14
"low bq, bad alignment, many samples",UPN2_039,19,33793224,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe33Val/c.97T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),800,21,833,"0,025210084",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-1,Neutral,28,Damaging,"26,18","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_053,19,33793224,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe33Val/c.97T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1598,28,1654,"0,0169286578",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-1,Neutral,28,Damaging,"27,5","14,25"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_008,19,33793224,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe33Val/c.97T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1484,27,1523,"0,0177281681",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-1,Neutral,28,Damaging,"26,5","14,26"
"low bq, low freq, many artifacts",UPN2_055,19,33793224,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe33Val/c.97T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1473,21,1516,"0,0138522427",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-1,Neutral,28,Damaging,"27,88",14
"low freq, bad alignment, many artifacts",UPN2_048,19,33793224,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe33Leu/c.97T>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1685,27,1747,"0,0154550658",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,81",Neutral,"0,247",Tolerated,"28,28","33,89"
"low bq, low freq, many artifacts",UPN2_058,19,33793224,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe33Ile/c.97T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),2031,29,2087,"0,0138955438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,96",Neutral,31,Damaging,"27,75","15,31"
"low freq, bad alignment, many artifacts",UPN2_048,19,33793228,G,C,missense_variant(MODERATE|MISSENSE|ttC/ttG|p.Phe31Leu/c.93C>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1811,39,1853,"0,0210469509",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,"0,094",Tolerated,"34,82","33,21"
"low bq, low freq, many artifacts, many samples",UPN2_041,19,33793229,A,T,missense_variant(MODERATE|MISSENSE|tTc/tAc|p.Phe31Tyr/c.92T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),2060,30,2096,"0,0143129771",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,33",Neutral,998,Tolerated,"33,04","16,07"
"low bq, low freq, many artifacts, many samples",UPN2_042,19,33793229,A,T,missense_variant(MODERATE|MISSENSE|tTc/tAc|p.Phe31Tyr/c.92T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),1435,22,1465,"0,0150170648",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,33",Neutral,998,Tolerated,"33,01","16,05"
"low bq, low freq, many artifacts, many samples",UPN2_048,19,33793229,A,T,missense_variant(MODERATE|MISSENSE|tTc/tAc|p.Phe31Tyr/c.92T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),1825,20,1853,"0,0107933081",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,33",Neutral,998,Tolerated,"33,01","16,2"
"low bq, low freq, many artifacts, many samples",UPN2_055,19,33793229,A,T,missense_variant(MODERATE|MISSENSE|tTc/tAc|p.Phe31Tyr/c.92T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),1480,27,1518,"0,0177865613",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,33",Neutral,998,Tolerated,"33,21","17,56"
"low bq, low freq, many artifacts",UPN2_058,19,33793229,A,T,missense_variant(MODERATE|MISSENSE|tTc/tAc|p.Phe31Tyr/c.92T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),2047,27,2087,"0,0129372305",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,33",Neutral,998,Tolerated,"32,93","17,04"
"low bq, low freq, many artifacts, many samples",UPN2_015,19,33793230,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe31Val/c.91T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1657,26,1704,"0,015258216",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,3,Damaging,"29,42","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_047,19,33793230,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe31Val/c.91T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2025,21,2069,"0,0101498308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,3,Damaging,"30,25","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_053,19,33793230,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe31Val/c.91T>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1605,20,1655,"0,0120845921",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,3,Damaging,"29,63",14
"low bq, low freq, many artifacts, many samples",UPN2_041,19,33793230,A,T,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe31Ile/c.91T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),2051,25,2097,"0,011921793",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,59",Neutral,4,Damaging,"29,5","15,6"
"low bq, low freq, many artifacts, many samples",UPN2_042,19,33793230,A,T,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe31Ile/c.91T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),1425,23,1465,"0,0156996587",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,59",Neutral,4,Damaging,"29,59","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_030,19,33793230,A,T,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe31Ile/c.91T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),1066,20,1094,"0,0182815356",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,59",Neutral,4,Damaging,"29,98","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_046,19,33793230,A,T,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe31Ile/c.91T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),1198,26,1234,"0,0210696921",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,59",Neutral,4,Damaging,"29,93","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_048,19,33793230,A,T,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe31Ile/c.91T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),1812,26,1855,"0,0140161725",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,59",Neutral,4,Damaging,"30,17","16,04"
"low bq, low freq, many artifacts, many samples",UPN2_036,19,33793230,A,T,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe31Ile/c.91T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),1543,25,1594,"0,0156838143",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,59",Neutral,4,Damaging,"29,5","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_050,19,33793230,A,T,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe31Ile/c.91T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),1371,23,1414,"0,0162659123",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,59",Neutral,4,Damaging,"29,53",14
"low bq, low freq, many artifacts, many samples",UPN2_037,19,33793230,A,T,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe31Ile/c.91T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),2012,27,2063,"0,0130877363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,59",Neutral,4,Damaging,"29,82","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_009,19,33793230,A,T,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe31Ile/c.91T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),1108,24,1144,"0,020979021",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,59",Neutral,4,Damaging,"29,1","15,46"
"low bq, low freq, many artifacts, many samples",UPN2_055,19,33793230,A,T,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe31Ile/c.91T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),1474,23,1518,"0,0151515152",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,59",Neutral,4,Damaging,"29,72","15,91"
"low bq, low freq, many artifacts",UPN2_058,19,33793230,A,T,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe31Ile/c.91T>A|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),2038,25,2087,"0,0119789171",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,59",Neutral,4,Damaging,"29,47","14,88"
"low bq, bad alignment, low freq, many artifacts",UPN2_050,19,33793239,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser28Arg/c.82A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1387,22,1417,"0,0155257586",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,6,Damaging,"26,18",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_041,19,33793250,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His24Pro/c.71A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2066,31,2107,"0,0147128619",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,2,Damaging,"24,44",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,19,33793250,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His24Pro/c.71A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1442,23,1471,"0,015635622",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,2,Damaging,"24,13","14,78"
"low bq, bad alignment, many samples",UPN2_043,19,33793250,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His24Pro/c.71A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),925,26,959,"0,0271115746",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,2,Damaging,"24,51","15,12"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,19,33793250,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His24Pro/c.71A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2032,23,2072,"0,0111003861",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,2,Damaging,"24,83","16,04"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_048,19,33793250,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His24Pro/c.71A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1831,23,1866,"0,0123258307",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,2,Damaging,"25,06","14,3"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,19,33793250,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His24Pro/c.71A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1384,26,1418,"0,0183356841",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,2,Damaging,"24,68",14
"low bq, bad alignment, many samples",UPN2_052,19,33793250,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His24Pro/c.71A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),956,23,990,"0,0232323232",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,2,Damaging,"24,39","15,35"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_038,19,33793250,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His24Pro/c.71A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2236,24,2277,"0,0105401845",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,2,Damaging,"25,3","14,92"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,19,33793250,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His24Pro/c.71A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1630,21,1661,"0,0126429862",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,2,Damaging,"24,34",14
"low bq, bad alignment, many samples",UPN2_007,19,33793250,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His24Pro/c.71A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),968,25,996,"0,0251004016",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,2,Damaging,"23,81",14
"low bq, bad alignment, low freq, many artifacts",UPN2_055,19,33793250,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His24Pro/c.71A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1486,24,1521,"0,0157790927",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,73",Neutral,2,Damaging,"24,58","14,92"
"low freq, many artifacts",UPN2_036,19,33793252,C,CG,frameshift_variant(HIGH||ccg/ccCg|p.His24fs/c.68dupC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|CG),1590,25,1599,"0,0156347717",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,rs137852729,YES,NO,NO,NO,NA,NA,NA,NA,"34,66",NA
"Inspected, homopolymer 6G, del and ins",UPN2_039,19,33793252,C,CG,frameshift_variant(HIGH||ccg/ccCg|p.His24fs/c.68dupC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|CG),832,62,834,"0,0743405276",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,rs137852729,YES,NO,NO,NO,NA,NA,NA,NA,"34,75",NA
"many samples, homopolymer 6C, low freq",UPN2_042,19,33793252,CG,C,frameshift_variant(HIGH||ccg/|p.Pro23fs/c.68delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1451,23,1477,"0,0155721056",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,12",NA
"many samples, homopolymer 6C, low freq",UPN2_047,19,33793252,CG,C,frameshift_variant(HIGH||ccg/|p.Pro23fs/c.68delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2061,28,2097,"0,0133524082",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,16",NA
"many samples, homopolymer 6C, low freq",UPN2_038,19,33793252,CG,C,frameshift_variant(HIGH||ccg/|p.Pro23fs/c.68delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2282,24,2309,"0,01039411",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,42",NA
"many samples, homopolymer 6C, low freq",UPN2_007,19,33793252,CG,C,frameshift_variant(HIGH||ccg/|p.Pro23fs/c.68delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),990,21,1015,"0,0206896552",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,29",NA
"low freq, many artifacts",UPN2_055,19,33793252,CG,C,frameshift_variant(HIGH||ccg/|p.Pro23fs/c.68delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1510,20,1532,"0,0130548303",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,28",NA
"many samples, homopolymer 6C, low freq",UPN2_058,19,33793252,CG,C,frameshift_variant(HIGH||ccg/|p.Pro23fs/c.68delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2099,26,2131,"0,0122008447",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,23",NA
"low bq, low freq, many artifacts, many samples",UPN2_041,19,33793260,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser21Arg/c.61A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4240,51,4325,"0,0117919075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,4,Damaging,"28,27","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_043,19,33793260,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser21Arg/c.61A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1821,20,1846,"0,0108342362",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,4,Damaging,"27,72",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_107,19,33793260,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser21Arg/c.61A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1334,22,1359,"0,0161883738",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,4,Damaging,"23,66","14,32"
"low freq, many artifacts, many samples",UPN2_048,19,33793262,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln20Pro/c.59A>C|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),3809,45,3889,"0,011571098",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,5",Neutral,55,Tolerated,"33,44","34,6"
"many samples, homopolymer 6C, low freq",UPN2_057,19,33793267,GT,G,frameshift_variant(HIGH||cac/|p.His18fs/c.53delA|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1646,21,1686,"0,012455516",0,0,0,1,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,1",NA
"low freq, many artifacts, many samples",UPN2_054,19,33793280,G,A,missense_variant(MODERATE|MISSENSE|cCg/cTg|p.Pro14Leu/c.41C>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),1325,20,1361,"0,0146950771",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,629,Tolerated,"34,48","33,6"
many samples,UPN2_090,19,33793284,GC,G,frameshift_variant(HIGH||cgg/|p.Pro14fs/c.36delG|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),880,33,915,"0,0360655738",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,23",NA
"low freq, many artifacts, many samples",UPN2_014,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2134,44,2179,"0,020192749",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,08",NA
"low freq, many artifacts, many samples",UPN2_015,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2677,38,2728,"0,0139296188",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,37",NA
"low freq, many artifacts, many samples",UPN2_016,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1239,20,1264,"0,0158227848",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,45",NA
many samples,UPN2_018,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),984,30,1016,"0,0295275591",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,5",NA
many samples,UPN2_019,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1424,38,1469,"0,0258679374",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,26",NA
many samples,UPN2_021,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1776,50,1833,"0,0272776869",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,28",NA
"low freq, many artifacts, many samples",UPN2_022,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2142,24,2169,"0,0110650069",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,32",NA
"low freq, many artifacts, many samples",UPN2_023,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2496,30,2529,"0,0118623962",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,24",NA
many samples,UPN2_041,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4209,106,4326,"0,0245030051",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,72",NA
"low freq, many artifacts, many samples",UPN2_025,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1853,22,1882,"0,0116896918",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,56",NA
"low freq, many artifacts, many samples",UPN2_026,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2100,38,2146,"0,0177073625",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,36",NA
"low freq, many artifacts, many samples",UPN2_027,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2718,41,2763,"0,0148389432",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,4",NA
many samples,UPN2_089,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),592,27,619,"0,0436187399",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,62",NA
"low freq, many artifacts, many samples",UPN2_042,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2304,30,2342,"0,0128095645",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,13",NA
many samples,UPN2_043,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1776,56,1846,"0,0303358613",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,03",NA
"low freq, many artifacts, many samples",UPN2_030,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2093,34,2134,"0,0159325211",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,31",NA
many samples,UPN2_031,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1031,24,1057,"0,0227057711",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,57",NA
"low freq, many artifacts, many samples",UPN2_045,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2235,29,2269,"0,0127809608",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,83",NA
"low freq, many artifacts, many samples",UPN2_046,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2709,40,2756,"0,0145137881",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,06",NA
"low freq, many artifacts, many samples",UPN2_033,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1584,20,1607,"0,0124455507",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,3",NA
"low freq, many artifacts, many samples",UPN2_047,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4060,68,4147,"0,0163973957",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,96",NA
"low freq, many artifacts, many samples",UPN2_048,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3799,79,3891,"0,0203032639",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,75",NA
"low freq, many artifacts, many samples",UPN2_036,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2968,38,3015,"0,0126036484",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,39",NA
"low freq, many artifacts, many samples",UPN2_049,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2214,31,2256,"0,0137411348",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,1",NA
"low freq, many artifacts, many samples",UPN2_050,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2548,45,2608,"0,0172546012",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,99",NA
"low freq, many artifacts, many samples",UPN2_037,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3475,47,3538,"0,0132843414",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,43",NA
many samples,UPN2_051,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1787,49,1843,"0,0265870863",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,92",NA
"many samples, GC region",UPN2_052,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1944,39,1995,"0,0195488722",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,08",NA
"low freq, many artifacts, many samples",UPN2_039,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1478,28,1507,"0,0185799602",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,46",NA
"low freq, many artifacts, many samples",UPN2_053,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2706,60,2778,"0,0215982721",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,11",NA
"low freq, many artifacts, many samples",UPN2_008,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4254,79,4342,"0,0181943805",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,14",NA
"low freq, many artifacts, many samples",UPN2_009,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2930,33,2977,"0,0110849849",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,08",NA
"low freq, many artifacts, many samples",UPN2_010,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1418,25,1444,"0,0173130194",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,02",NA
"low freq, many artifacts, many samples",UPN2_055,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2602,27,2635,"0,0102466793",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,1",NA
many samples,UPN2_056,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1345,52,1403,"0,0370634355",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,01",NA
"many samples, GC region",UPN2_090,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),835,80,915,"0,087431694",0,1,0,1,0,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,5",NA
"low freq, many artifacts, many samples",UPN2_057,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1654,27,1688,"0,0159952607",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,91",NA
"low freq, many artifacts, many samples",UPN2_058,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3642,43,3717,"0,0115684692",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,16",NA
many samples,UPN2_091,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),816,21,840,"0,025",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,52",NA
"many samples, GC region",UPN2_094,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),759,33,795,"0,041509434",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,52",NA
"many samples, GC region",UPN2_096,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),678,38,717,"0,0529986053",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,73",NA
many samples,UPN2_097,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),903,36,940,"0,0382978723",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,46",NA
"many samples, GC region",UPN2_100,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),480,24,504,"0,0476190476",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,67",NA
many samples,UPN2_101,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),567,30,598,"0,0501672241",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,32",NA
many samples,UPN2_102,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),683,21,705,"0,029787234",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,44",NA
"many samples, GC region",UPN2_103,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),500,21,521,"0,0403071017",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,41",NA
"many samples, GC region",UPN2_104,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),712,30,743,"0,0403768506",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,62",NA
"many samples, GC region",UPN2_105,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),384,23,408,"0,056372549",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,59",NA
many samples,UPN2_106,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),772,38,813,"0,0467404674",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,52",NA
many samples,UPN2_107,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1303,51,1360,"0,0375",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,42",NA
many samples,UPN2_108,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1188,49,1244,"0,0393890675",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,6",NA
many samples,UPN2_109,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),867,20,891,"0,0224466891",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,51",NA
"many samples, GC region",UPN2_111,19,33793288,CG,C,frameshift_variant(HIGH||ccg/|p.Pro11fs/c.32delC|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),657,23,684,"0,033625731",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,53",NA
"low freq, many artifacts, many samples",UPN2_014,19,33793290,GC,G,frameshift_variant(HIGH||gag/|p.Glu10fs/c.30delG|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2135,28,2179,"0,0128499312",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,44",NA
"low freq, many artifacts, many samples",UPN2_045,19,33793290,GC,G,frameshift_variant(HIGH||gag/|p.Glu10fs/c.30delG|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2225,35,2269,"0,0154252975",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,15",NA
"low freq, many artifacts, many samples",UPN2_055,19,33793290,GC,G,frameshift_variant(HIGH||gag/|p.Glu10fs/c.30delG|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2585,41,2635,"0,0155597723",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,2",NA
"inspected, strandbias",UPN2_057,19,33793290,GC,G,frameshift_variant(HIGH||gag/|p.Glu10fs/c.30delG|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),1646,40,1687,"0,0237107291",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,25",NA
"low freq, many artifacts",UPN2_036,19,33793292,TC,T,frameshift_variant(HIGH||gag/|p.Glu10fs/c.28delG|358|CEBPA|protein_coding|CODING|ENST00000498907|1|T),2972,34,3015,"0,0112769486",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,46",NA
"low freq, many artifacts, many samples",UPN2_047,19,33793295,GC,G,frameshift_variant(HIGH||gcg/|p.Ala9fs/c.25delG|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),4074,62,4145,"0,0149577805",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,15",NA
many samples,UPN2_049,19,33793295,GC,G,frameshift_variant(HIGH||gcg/|p.Ala9fs/c.25delG|358|CEBPA|protein_coding|CODING|ENST00000498907|1|G),2180,73,2256,"0,032358156",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,09",NA
"many samples, strandbias",UPN2_041,19,33793307,T,A,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp5Val/c.14A>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),4144,51,4315,"0,0118192352",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,4",Neutral,"0,001",Damaging,"31,8","26,84"
many samples,UPN2_001,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),639,65,708,"0,0918079096",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"32,12","31,49"
"many samples, strandbias",UPN2_014,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2013,144,2171,"0,0663288807",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"32,38","31,62"
"many samples, strandbias",UPN2_015,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2523,187,2719,"0,068775285",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"31,49","31,27"
"many samples, strandbias",UPN2_016,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1157,101,1263,"0,0799683294",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"31,73","31,33"
"many samples, strandbias",UPN2_017,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),614,64,681,"0,093979442",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"31,93","31,89"
"many samples, strandbias",UPN2_018,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),910,98,1010,"0,097029703",0,1,0,0,1,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"31,15","31,66"
many samples,UPN2_019,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1361,92,1456,"0,0631868132",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"32,41","31,57"
many samples,UPN2_020,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1088,97,1187,"0,0817186184",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"32,79","31,39"
many samples,UPN2_021,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1677,141,1829,"0,0770913067",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"32,24","31,35"
many samples,UPN2_002,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),765,61,828,"0,0736714976",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"32,2","31,7"
"many samples, strandbias",UPN2_022,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2018,129,2160,"0,0597222222",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"32,99","31,59"
"many samples, strandbias",UPN2_023,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2311,193,2517,"0,0766785856",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"32,37","31,4"
many samples,UPN2_041,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),4144,118,4315,"0,0273464658",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"31,8","31,61"
"many samples, strandbias",UPN2_024,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),655,63,721,"0,0873786408",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"31,64","31,78"
"many samples, strandbias",UPN2_025,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1696,173,1875,"0,0922666667",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"31,25","31,73"
many samples,UPN2_026,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1961,176,2142,"0,0821661998",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"31,95","31,66"
"many samples, strandbias",UPN2_027,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2526,199,2741,"0,0726012404",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"32,66","31,86"
many samples,UPN2_089,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),589,30,619,"0,0484652666",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"31,43","31,4"
"many samples, strandbias",UPN2_042,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2186,119,2313,"0,0514483355",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"31,27","31,43"
"many samples, strandbias",UPN2_028,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1594,109,1708,"0,0638173302",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"32,09","32,01"
"many samples, strandbias",UPN2_043,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1773,62,1842,"0,0336590662",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"31,8","31,89"
"low freq, many artifacts, many samples",UPN2_044,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1387,28,1424,"0,0196629213",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"33,39","32,29"
"many samples, strandbias",UPN2_029,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1754,135,1895,"0,0712401055",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"32,71","31,79"
"many samples, strandbias",UPN2_030,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1982,132,2119,"0,0622935347",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"32,3","31,89"
"many samples, strandbias",UPN2_031,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),948,101,1051,"0,0960989534",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"31,59","31,22"
"many samples, strandbias",UPN2_005,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),214,31,246,"0,1260162602",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"30,91","31,42"
"many samples, strandbias",UPN2_045,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2173,81,2259,"0,0358565737",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"31,24","31,21"
many samples,UPN2_032,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),769,49,821,"0,059683313",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"32,4",32
"many samples, strandbias",UPN2_046,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2599,131,2740,"0,047810219",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"32,06","31,85"
"many samples, strandbias",UPN2_033,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1488,105,1601,"0,06558401",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"32,35","31,73"
many samples,UPN2_034,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),526,23,555,"0,0414414414",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"32,99","30,74"
"many samples, strandbias",UPN2_047,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3961,140,4125,"0,0339393939",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"31,88","31,79"
"many samples, strandbias",UPN2_048,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3656,164,3840,"0,0427083333",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"32,06","31,68"
"many samples, strandbias",UPN2_035,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1493,108,1607,"0,0672059739",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"32,6","31,33"
"many samples, strandbias",UPN2_036,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2766,221,3007,"0,0734951779",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"32,19","31,73"
many samples,UPN2_006,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),394,41,441,"0,0929705215",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"32,16",32
"many samples, strandbias",UPN2_049,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2149,85,2252,"0,0377442274",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"32,16","31,28"
"many samples, strandbias",UPN2_050,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2513,75,2603,"0,0288129082",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"31,41","31,48"
"many samples, strandbias",UPN2_037,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3237,275,3525,"0,0780141844",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"32,04","31,89"
"many samples, strandbias",UPN2_051,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1769,60,1836,"0,0326797386",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"31,32","31,9"
many samples,UPN2_052,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1929,56,1994,"0,0280842528",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"31,9","31,41"
"many samples, strandbias",UPN2_038,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3437,317,3760,"0,0843085106",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"31,86","31,71"
"inspected, many samples, strandbias",UPN2_039,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1383,118,1506,"0,0783532537",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,32,"31,2"
many samples,UPN2_053,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2622,125,2763,"0,0452406804",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"31,16","31,54"
many samples,UPN2_054,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1299,51,1357,"0,0375829035",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"31,54","30,94"
"many samples, strandbias",UPN2_007,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2219,182,2410,"0,0755186722",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"32,46","31,8"
"many samples, strandbias",UPN2_008,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3963,334,4317,"0,077368543",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"32,9","31,77"
many samples,UPN2_009,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2760,198,2971,"0,0666442275",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"32,76","31,36"
"many samples, strandbias",UPN2_010,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1328,103,1441,"0,0714781402",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"32,55","31,3"
many samples,UPN2_011,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1131,85,1219,"0,0697292863",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"32,65","31,4"
"many samples, strandbias",UPN2_055,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),2492,130,2629,"0,0494484595",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"31,47","31,32"
"many samples, strandbias",UPN2_056,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1346,40,1392,"0,0287356322",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"32,55","31,95"
many samples,UPN2_090,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),884,27,912,"0,0296052632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"31,49",32
"many samples, strandbias",UPN2_057,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1616,55,1682,"0,0326991677",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"32,06","30,96"
"many samples, strandbias",UPN2_058,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),3457,234,3698,"0,0632774473",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"31,74","31,49"
"many samples, strandbias",UPN2_012,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),981,81,1062,"0,0762711864",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"33,18","31,6"
"many samples, strandbias",UPN2_040,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),905,48,956,"0,050209205",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"32,82","31,79"
"many samples, strandbias",UPN2_013,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),526,70,599,"0,1168614357",0,1,0,0,1,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"31,78","31,69"
"many samples, strandbias",UPN2_091,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),803,36,840,"0,0428571429",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"31,89","30,81"
many samples,UPN2_093,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),284,27,311,"0,0868167203",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"30,76",32
many samples,UPN2_094,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),761,29,791,"0,0366624526",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"30,34","31,52"
many samples,UPN2_095,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),656,33,689,"0,0478955007",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"30,79",32
many samples,UPN2_096,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),679,34,713,"0,0476858345",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"30,36",32
many samples,UPN2_097,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),880,54,936,"0,0576923077",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"30,57",32
many samples,UPN2_098,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),512,20,532,"0,037593985",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"31,36",32
many samples,UPN2_099,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),424,30,455,"0,0659340659",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"30,45","31,4"
many samples,UPN2_101,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),576,20,596,"0,033557047",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"31,11","30,2"
many samples,UPN2_102,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),661,30,693,"0,0432900433",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"30,71","31,4"
many samples,UPN2_103,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),493,26,519,"0,0500963391",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"29,82","32,15"
many samples,UPN2_104,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),687,52,739,"0,0703653586",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"30,32","31,23"
many samples,UPN2_106,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),779,30,810,"0,037037037",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"30,44","30,3"
many samples,UPN2_107,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1297,54,1354,"0,0398818316",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"30,95",32
many samples,UPN2_108,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),1192,42,1237,"0,0339531124",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"30,74","31,57"
many samples,UPN2_109,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),836,52,888,"0,0585585586",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"31,12","31,31"
many samples,UPN2_110,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),824,30,856,"0,035046729",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"30,33",32
"inspected, strandbias",UPN2_111,19,33793307,T,C,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp5Gly/c.14A>G|358|CEBPA|protein_coding|CODING|ENST00000498907|1|C),646,28,676,"0,0414201183",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,41",Neutral,"0,01",Damaging,"30,37","31,82"
"low bq, low freq, many artifacts, many samples",UPN2_041,19,33793316,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu2Val/c.5A>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),2182,25,2216,"0,0112815884",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,13",Deleterious,1,Damaging,"33,77","20,72"
"low bq, low freq, many artifacts, many samples",UPN2_047,19,33793316,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu2Val/c.5A>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),2040,25,2071,"0,0120714631",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,13",Deleterious,1,Damaging,"33,71","15,76"
"low bq, low freq, many artifacts, many samples",UPN2_048,19,33793316,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu2Val/c.5A>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),1987,23,2020,"0,0113861386",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,13",Deleterious,1,Damaging,"33,56","17,83"
"low bq, low freq, many artifacts",UPN2_058,19,33793316,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu2Val/c.5A>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),1593,24,1622,"0,0147965475",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,13",Deleterious,1,Damaging,"34,13","19,12"
"low bq, low freq, many artifacts, many samples",UPN2_041,19,33793320,T,A,initiator_codon_variant(LOW|MISSENSE|Atg/Ttg|p.Met1?/c.1A>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),2169,33,2216,"0,0148916968",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,0,Damaging,"32,66",18
"low bq, low freq, many artifacts, many samples",UPN2_044,19,33793320,T,A,initiator_codon_variant(LOW|MISSENSE|Atg/Ttg|p.Met1?/c.1A>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),1061,21,1090,"0,019266055",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,0,Damaging,"33,02","20,1"
"low bq, low freq, many artifacts, many samples",UPN2_046,19,33793320,T,A,initiator_codon_variant(LOW|MISSENSE|Atg/Ttg|p.Met1?/c.1A>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),1467,24,1497,"0,0160320641",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,0,Damaging,"32,75","18,58"
"low bq, low freq, many artifacts, many samples",UPN2_047,19,33793320,T,A,initiator_codon_variant(LOW|MISSENSE|Atg/Ttg|p.Met1?/c.1A>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),2029,26,2070,"0,0125603865",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,0,Damaging,"32,45","16,23"
"low bq, low freq, many artifacts, many samples",UPN2_048,19,33793320,T,A,initiator_codon_variant(LOW|MISSENSE|Atg/Ttg|p.Met1?/c.1A>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),1968,32,2016,"0,0158730159",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,0,Damaging,"32,67","17,72"
"low bq, low freq, many artifacts, many samples",UPN2_036,19,33793320,T,A,initiator_codon_variant(LOW|MISSENSE|Atg/Ttg|p.Met1?/c.1A>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),1379,20,1416,"0,0141242938",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,0,Damaging,"33,9","20,6"
"low bq, low freq, many artifacts",UPN2_049,19,33793320,T,A,initiator_codon_variant(LOW|MISSENSE|Atg/Ttg|p.Met1?/c.1A>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),1324,26,1358,"0,0191458027",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,0,Damaging,"32,76","16,73"
"inspected, many artifacts",UPN2_041,19,33793341,G,A,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-21C>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),2165,29,2210,"0,0131221719",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,,,,,"31,96","30,83"
"low bq, low freq, many artifacts, many samples",UPN2_041,19,33793345,T,A,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-25A>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),2171,34,2209,"0,0153915799",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,37","15,71"
"low bq, low freq, many artifacts, many samples",UPN2_047,19,33793345,T,A,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-25A>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),2025,37,2067,"0,0179003387",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,68","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_048,19,33793345,T,A,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-25A>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),1972,35,2010,"0,0174129353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,36","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_049,19,33793345,T,A,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-25A>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),1329,22,1356,"0,0162241888",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,31","17,86"
"low bq, low freq, many artifacts",UPN2_058,19,33793345,T,A,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-25A>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),1589,22,1620,"0,0135802469",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,75","15,82"
"low bq, low freq, many artifacts, many samples",UPN2_041,19,33793370,T,A,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-50A>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),4340,62,4457,"0,0139107023",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,19","18,5"
"low bq, low freq, many artifacts, many samples",UPN2_045,19,33793370,T,A,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-50A>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),1966,36,2017,"0,0178482895",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,18","16,5"
"low bq, low freq, many artifacts, many samples",UPN2_046,19,33793370,T,A,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-50A>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),2964,36,3023,"0,0119087",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,4","17,44"
"low bq, low freq, many artifacts, many samples",UPN2_047,19,33793370,T,A,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-50A>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),4086,43,4157,"0,0103439981",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,27","15,95"
"low bq, low freq, many artifacts, many samples",UPN2_048,19,33793370,T,A,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-50A>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),3991,41,4056,"0,0101084813",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,6","16,93"
"low bq, low freq, many artifacts, many samples",UPN2_049,19,33793370,T,A,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-50A>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),2689,30,2732,"0,0109809663",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,29,"20,07"
"low bq, low freq, many artifacts, many samples",UPN2_050,19,33793370,T,A,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-50A>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),2356,27,2394,"0,0112781955",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,37","17,44"
"low bq, low freq, many artifacts, many samples",UPN2_052,19,33793370,T,A,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-50A>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),1996,21,2033,"0,0103295622",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,87","16,43"
"low bq, low freq, many artifacts",UPN2_055,19,33793370,T,A,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-50A>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),2186,27,2243,"0,0120374498",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,62","17,78"
"inspected, many artifacts",UPN2_010,19,33793396,C,A,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-76G>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),1708,21,1731,"0,0121317158",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,,,,,"33,86","29,76"
"inspected, many artifacts",UPN2_036,19,33793397,G,A,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-77C>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),2768,56,2848,"0,0196629213",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,,,,,"30,7","28,82"
"low bq, low freq, many artifacts, many samples",UPN2_046,19,33793405,T,A,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-85A>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),1578,21,1608,"0,0130597015",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,03","18,33"
"low bq, low freq, many artifacts, many samples",UPN2_047,19,33793405,T,A,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-85A>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),2152,30,2196,"0,0136612022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,15","15,7"
"low bq, low freq, many artifacts, many samples",UPN2_048,19,33793405,T,A,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-85A>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),2106,27,2149,"0,0125639832",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,34","16,78"
"low bq, low freq, many artifacts",UPN2_055,19,33793405,T,A,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-85A>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),1179,22,1210,"0,0181818182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,45","16,64"
"bad alignment, low freq, many artifacts",UPN2_048,19,33793456,G,A,5_prime_UTR_premature_start_codon_gain_variant(LOW|||c.-136C>T|358|CEBPA|protein_coding|CODING|ENST00000498907|1|A),2003,50,2054,"0,0243427459",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,,,,,"34,54","35,66"
"bad alignment, low freq, many artifacts",UPN2_093,20,31022241,C,A,missense_variant(MODERATE|MISSENSE|Ctt/Att|p.Leu576Ile/c.1726C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),7888,102,7996,"0,0127563782",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,92",Neutral,"0,005",Damaging,"34,16","32,46"
"bad alignment, low freq, many artifacts",UPN2_048,20,31022257,C,T,missense_variant(MODERATE|MISSENSE|cCa/cTa|p.Pro581Leu/c.1742C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),7084,113,7222,"0,0156466353",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"2,47E-005",NO,NO,"-7,36",Deleterious,"0,003",Damaging,"31,29","34,24"
"low bq, low freq, many artifacts, many samples",UPN2_059,20,31022266,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val584Gly/c.1751T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),11810,126,11990,"0,0105087573",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"28,46","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_060,20,31022266,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val584Gly/c.1751T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),18852,199,19179,"0,010375932",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"28,68","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_062,20,31022266,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val584Gly/c.1751T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),16046,202,16343,"0,0123600318",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"28,41","15,34"
"low bq, low freq, many artifacts, many samples",UPN2_064,20,31022266,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val584Gly/c.1751T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),12560,141,12790,"0,0110242377",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"28,65","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_065,20,31022266,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val584Gly/c.1751T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),12702,129,12895,"0,0100038775",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"28,68","15,81"
"low bq, low freq, many artifacts, many samples",UPN2_068,20,31022266,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val584Gly/c.1751T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),16799,202,17116,"0,0118018229",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"28,17","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_069,20,31022266,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val584Gly/c.1751T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),20986,246,21356,"0,0115190111",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"28,35","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_070,20,31022266,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val584Gly/c.1751T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),14120,156,14391,"0,0108401084",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"28,18","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_073,20,31022266,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val584Gly/c.1751T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),12200,131,12386,"0,0105764573",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"28,55","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_076,20,31022266,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val584Gly/c.1751T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),17251,215,17547,"0,0122528067",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"28,29","15,34"
"low bq, low freq, many artifacts, many samples",UPN2_077,20,31022266,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val584Gly/c.1751T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),19118,215,19444,"0,0110573956",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"28,4","15,17"
"low bq, low freq, many artifacts, many samples",UPN2_078,20,31022266,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val584Gly/c.1751T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),19943,228,20279,"0,0112431579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"28,37","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_080,20,31022266,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val584Gly/c.1751T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),17960,200,18252,"0,0109577033",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"28,6","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_083,20,31022266,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val584Gly/c.1751T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),21060,259,21413,"0,012095456",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"28,32","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_084,20,31022266,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val584Gly/c.1751T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),18942,236,19283,"0,0122387595",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"28,35","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_085,20,31022266,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val584Gly/c.1751T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),14572,183,14836,"0,0123348611",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"28,35","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_086,20,31022266,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val584Gly/c.1751T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),10451,108,10631,"0,0101589691",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"28,18","14,96"
"low bq, low freq, many artifacts",UPN2_087,20,31022266,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val584Gly/c.1751T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),20692,237,21056,"0,0112556991",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"28,58","14,65"
"bad alignment, low freq, many artifacts",UPN2_048,20,31022278,A,C,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln588Pro/c.1763A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),7345,90,7484,"0,0120256547",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,"0,02",Damaging,"34,78","34,11"
"low freq, many artifacts",UPN2_006,20,31022279,GC,G,frameshift_variant(HIGH||ccc/|p.Thr590fs/c.1767delC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G|INFO_REALIGN_3_PRIME),3542,63,3617,"0,0174177495",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,35",NA
"inspected, many samples, many artifacts",UPN2_043,20,31022288,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr591*/c.1773C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),11049,367,11453,"0,0320440059",0,0,0,0,1,1,0,1,3,NO,NO,COSM1681609,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NA,NO,NO,NA,NA,NA,NA,"35,2","34,31"
"low bq, low freq, many artifacts",UPN2_017,20,31022320,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu602Val/c.1805A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5521,63,5617,"0,0112159516",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,83",Neutral,1,Damaging,"34,74","16,46"
"low freq, many artifacts, many samples",UPN2_090,20,31022322,T,G,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser603Ala/c.1807T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),6228,74,6339,"0,0116737656",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,29",Neutral,493,Tolerated,"35,16","35,35"
"low freq, many artifacts, many samples",UPN2_093,20,31022322,T,G,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser603Ala/c.1807T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),4611,62,4695,"0,0132055378",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,29",Neutral,493,Tolerated,"35,15","34,45"
"low freq, many artifacts, many samples",UPN2_072,20,31022322,T,G,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser603Ala/c.1807T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),7222,84,7370,"0,0113975577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,29",Neutral,493,Tolerated,"34,47","33,29"
"low freq, many artifacts, many samples",UPN2_001,20,31022323,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser603Tyr/c.1808C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),6151,125,6309,"0,0198129656",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Tolerated,"35,6","35,64"
"low freq, many artifacts, many samples",UPN2_018,20,31022323,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser603Tyr/c.1808C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),7995,83,8097,"0,0102507101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Tolerated,"35,61","35,42"
"low freq, many artifacts, many samples",UPN2_003,20,31022323,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser603Tyr/c.1808C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),1577,20,1600,"0,0125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Tolerated,"35,62",36
"many samples, low freq",UPN2_026,20,31022323,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser603Tyr/c.1808C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),14134,159,14323,"0,0111010263",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Tolerated,"35,57","35,23"
"low freq, many artifacts, many samples",UPN2_089,20,31022323,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser603Tyr/c.1808C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),7935,99,8063,"0,0122783083",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Tolerated,"35,57","35,52"
"low freq, many artifacts, many samples",UPN2_043,20,31022323,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser603Tyr/c.1808C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),11289,126,11453,"0,0110014843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Tolerated,"35,42","35,48"
"low freq, many artifacts, many samples",UPN2_044,20,31022323,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser603Tyr/c.1808C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),2757,35,2795,"0,0125223614",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Tolerated,"35,36","34,2"
"low freq, many artifacts, many samples",UPN2_005,20,31022323,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser603Tyr/c.1808C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),2725,37,2768,"0,013367052",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Tolerated,"35,59",36
"low freq, many artifacts, many samples",UPN2_045,20,31022323,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser603Tyr/c.1808C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),13919,180,14173,"0,0127002046",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Tolerated,"35,46","35,71"
"many samples, low freq",UPN2_035,20,31022323,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser603Tyr/c.1808C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),10157,107,10276,"0,0104126119",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Tolerated,"35,58","35,76"
"low freq, many artifacts, many samples",UPN2_050,20,31022323,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser603Tyr/c.1808C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),13015,156,13232,"0,011789601",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Tolerated,"35,43","35,92"
"many samples, low freq",UPN2_037,20,31022323,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser603Tyr/c.1808C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),20239,214,20495,"0,0104415711",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Tolerated,"35,6","35,65"
"low freq, many artifacts, many samples",UPN2_051,20,31022323,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser603Tyr/c.1808C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),11624,132,11824,"0,0111637348",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Tolerated,"35,43",35
"low freq, many artifacts, many samples",UPN2_054,20,31022323,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser603Tyr/c.1808C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),9437,104,9570,"0,0108672936",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Tolerated,"35,43","34,94"
"low freq, many artifacts, many samples",UPN2_009,20,31022323,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser603Tyr/c.1808C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),21135,219,21417,"0,0102255218",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Tolerated,"35,59","35,66"
"low freq, many artifacts, many samples",UPN2_011,20,31022323,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser603Tyr/c.1808C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),15572,158,15745,"0,0100349317",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Tolerated,"35,59","35,56"
"low freq, many artifacts, many samples",UPN2_040,20,31022323,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser603Tyr/c.1808C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),8183,84,8284,"0,010140029",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Tolerated,"35,56","35,48"
"low freq, many artifacts, many samples",UPN2_013,20,31022323,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser603Tyr/c.1808C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),5422,80,5520,"0,0144927536",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Tolerated,"35,55","35,72"
"low freq, many artifacts, many samples",UPN2_091,20,31022323,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser603Tyr/c.1808C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),5581,92,5681,"0,016194332",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Tolerated,"35,54",36
"low freq, many artifacts, many samples",UPN2_092,20,31022323,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser603Tyr/c.1808C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),3459,56,3519,"0,0159136118",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Tolerated,"35,59","35,34"
"low freq, many artifacts, many samples",UPN2_093,20,31022323,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser603Tyr/c.1808C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),4588,64,4695,"0,0136315229",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Tolerated,"35,57","35,19"
"many samples, low freq",UPN2_061,20,31022323,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser603Tyr/c.1808C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),8823,124,8968,"0,0138269402",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Tolerated,"35,45","35,43"
"low freq, many artifacts, many samples",UPN2_062,20,31022323,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser603Tyr/c.1808C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),8459,97,8560,"0,0113317757",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Tolerated,"35,49","35,96"
"low freq, many artifacts, many samples",UPN2_064,20,31022323,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser603Tyr/c.1808C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),6625,77,6728,"0,0114447087",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Tolerated,"35,45","35,47"
"low freq, many artifacts, many samples",UPN2_065,20,31022323,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser603Tyr/c.1808C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),6663,80,6772,"0,0118133491",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Tolerated,"35,5","35,26"
"many samples, low freq",UPN2_067,20,31022323,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser603Tyr/c.1808C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),9292,105,9423,"0,0111429481",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Tolerated,"35,49","35,5"
"many samples, low freq",UPN2_069,20,31022323,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser603Tyr/c.1808C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),10814,124,10956,"0,0113179993",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Tolerated,"35,5","35,67"
"many samples, low freq",UPN2_070,20,31022323,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser603Tyr/c.1808C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),7270,96,7384,"0,0130010834",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Tolerated,"35,42","35,72"
"many samples, low freq",UPN2_076,20,31022323,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser603Tyr/c.1808C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),8926,98,9046,"0,0108335176",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Tolerated,"35,57","35,55"
"many samples, low freq",UPN2_077,20,31022323,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser603Tyr/c.1808C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),9813,116,9953,"0,0116547775",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Tolerated,"35,49","35,55"
"many samples, low freq",UPN2_086,20,31022323,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser603Tyr/c.1808C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),5373,93,5478,"0,0169769989",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Tolerated,"35,49","35,19"
"many samples, low freq",UPN2_087,20,31022323,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser603Tyr/c.1808C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),10710,110,10846,"0,0101419878",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Tolerated,"35,5","35,39"
"low freq, many artifacts, many samples",UPN2_095,20,31022323,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser603Tyr/c.1808C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),6923,71,7010,"0,010128388",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Tolerated,"35,53",36
"low freq, many artifacts, many samples",UPN2_099,20,31022323,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser603Tyr/c.1808C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),4097,43,4152,"0,0103564547",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Tolerated,"35,63","35,65"
"many samples, low freq",UPN2_100,20,31022323,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser603Tyr/c.1808C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),6103,71,6190,"0,0114701131",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Tolerated,"35,55","35,63"
"low freq, many artifacts, many samples",UPN2_101,20,31022323,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser603Tyr/c.1808C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),6137,70,6232,"0,0112323492",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Tolerated,"35,64","35,69"
"low freq, many artifacts, many samples",UPN2_103,20,31022323,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser603Tyr/c.1808C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),6766,73,6885,"0,0106027596",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Tolerated,"35,59","35,64"
"low freq, many artifacts, many samples",UPN2_105,20,31022323,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser603Tyr/c.1808C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),7082,90,7185,"0,012526096",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Tolerated,"35,56","35,76"
"low freq, many artifacts, many samples",UPN2_106,20,31022323,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser603Tyr/c.1808C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),10208,119,10364,"0,0114820533",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Tolerated,"35,52","35,32"
"low freq, many artifacts",UPN2_111,20,31022323,C,A,missense_variant(MODERATE|MISSENSE|tCc/tAc|p.Ser603Tyr/c.1808C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),8635,93,8750,"0,0106285714",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Tolerated,"35,58","35,48"
"low freq, many artifacts, many samples",UPN2_052,20,31022325,T,G,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser604Ala/c.1810T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),11542,142,11753,"0,0120820216",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,98",Neutral,32,Damaging,"35,57","35,39"
"low freq, many artifacts, many samples",UPN2_056,20,31022325,T,G,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser604Ala/c.1810T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),2422,40,2474,"0,0161681487",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,98",Neutral,32,Damaging,"35,55","35,25"
"low freq, many artifacts, many samples",UPN2_001,20,31022328,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys605Ser/c.1813T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),6199,66,6309,"0,0104612458",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,43",Neutral,624,Tolerated,"35,54","34,09"
"inspected, many samples, many artifacts",UPN2_017,20,31022328,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys605Ser/c.1813T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),5528,62,5622,"0,0110281039",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,43",Neutral,"0,624",Tolerated,"34,94","34,66"
"many samples, low freq",UPN2_018,20,31022328,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys605Ser/c.1813T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),7948,103,8097,"0,0127207608",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,43",Neutral,"0,624",Tolerated,"35,33","34,92"
"many samples, low freq",UPN2_043,20,31022328,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys605Ser/c.1813T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),11233,132,11454,"0,0115243583",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,43",Neutral,"0,624",Tolerated,"35,44","33,81"
"low freq, many artifacts, many samples",UPN2_031,20,31022328,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys605Ser/c.1813T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),8596,95,8744,"0,0108645929",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,43",Neutral,624,Tolerated,"35,44","34,53"
"many samples, low freq",UPN2_045,20,31022328,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys605Ser/c.1813T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),13891,168,14167,"0,0118585445",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,43",Neutral,"0,624",Tolerated,"35,49","34,71"
"many samples, low freq",UPN2_046,20,31022328,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys605Ser/c.1813T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),15623,177,15910,"0,0111250786",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,43",Neutral,"0,624",Tolerated,"35,42","34,11"
"low freq, many artifacts, many samples",UPN2_051,20,31022328,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys605Ser/c.1813T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),11573,128,11824,"0,0108254398",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,43",Neutral,624,Tolerated,"35,43","34,78"
"many samples, low freq",UPN2_011,20,31022328,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys605Ser/c.1813T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),15415,209,15745,"0,0132740553",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,43",Neutral,"0,624",Tolerated,"35,58","35,1"
"many samples, low freq",UPN2_059,20,31022328,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys605Ser/c.1813T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),6075,74,6172,"0,0119896306",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,43",Neutral,"0,624",Tolerated,"35,49","35,59"
"low freq, many artifacts, many samples",UPN2_012,20,31022328,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys605Ser/c.1813T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),8249,139,8450,"0,0164497041",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,43",Neutral,624,Tolerated,"35,54","35,68"
"many samples, low freq",UPN2_060,20,31022328,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys605Ser/c.1813T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),9713,157,9924,"0,0158202338",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,43",Neutral,"0,624",Tolerated,"35,5","35,34"
"low freq, many artifacts, many samples",UPN2_013,20,31022328,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys605Ser/c.1813T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),5418,69,5520,"0,0125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,43",Neutral,624,Tolerated,"35,51","35,3"
"low freq, many artifacts, many samples",UPN2_093,20,31022328,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys605Ser/c.1813T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),4603,64,4695,"0,0136315229",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,43",Neutral,624,Tolerated,"35,67","35,66"
"many samples, low freq",UPN2_061,20,31022328,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys605Ser/c.1813T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),8793,122,8968,"0,0136039251",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,43",Neutral,"0,624",Tolerated,"35,51","35,33"
"many samples, low freq",UPN2_063,20,31022328,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys605Ser/c.1813T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),9042,103,9189,"0,0112090543",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,43",Neutral,"0,624",Tolerated,"35,47","35,17"
"low freq, many artifacts, many samples",UPN2_065,20,31022328,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys605Ser/c.1813T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),6654,74,6772,"0,0109273479",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,43",Neutral,624,Tolerated,"35,44","34,76"
"many samples, low freq",UPN2_066,20,31022328,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys605Ser/c.1813T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),8778,120,8967,"0,0133824021",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,43",Neutral,"0,624",Tolerated,"35,56","35,51"
"many samples, low freq",UPN2_071,20,31022328,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys605Ser/c.1813T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),6707,79,6802,"0,0116142311",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,43",Neutral,"0,624",Tolerated,"35,4","35,34"
"many samples, low freq",UPN2_075,20,31022328,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys605Ser/c.1813T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),11536,170,11782,"0,0144287897",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,43",Neutral,"0,624",Tolerated,"35,47","35,38"
"many samples, low freq",UPN2_077,20,31022328,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys605Ser/c.1813T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),9724,187,9953,"0,018788305",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,43",Neutral,"0,624",Tolerated,"35,57","35,58"
"many samples, low freq",UPN2_082,20,31022328,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys605Ser/c.1813T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),10029,109,10208,"0,0106778997",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,43",Neutral,"0,624",Tolerated,"35,53","35,25"
"many samples, low freq",UPN2_083,20,31022328,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys605Ser/c.1813T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),10854,127,11048,"0,0114952933",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,43",Neutral,"0,624",Tolerated,"35,51","35,15"
"many samples, low freq",UPN2_084,20,31022328,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys605Ser/c.1813T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),9798,103,9949,"0,0103527993",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,43",Neutral,"0,624",Tolerated,"35,52","34,89"
"many samples, low freq",UPN2_086,20,31022328,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys605Ser/c.1813T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),5377,65,5478,"0,0118656444",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,43",Neutral,"0,624",Tolerated,"35,5","35,88"
"many samples, low freq",UPN2_100,20,31022328,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys605Ser/c.1813T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),6059,75,6190,"0,0121163166",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,43",Neutral,"0,624",Tolerated,"35,63","35,83"
"low freq, many artifacts",UPN2_106,20,31022328,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys605Ser/c.1813T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),10204,107,10364,"0,0103241992",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,43",Neutral,624,Tolerated,"35,61","35,31"
"low freq, many artifacts",UPN2_056,20,31022330,C,G,missense_variant(MODERATE|MISSENSE|tgC/tgG|p.Cys605Trp/c.1815C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),2427,25,2474,"0,010105093",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,2",Neutral,5,Damaging,"35,37","35,12"
"low freq, many artifacts",UPN2_036,20,31022331,C,CG,frameshift_variant(HIGH||ggt/ggGt|p.Trp608fs/c.1820dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|CG|INFO_REALIGN_3_PRIME),9928,113,9964,"0,011340827",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,31",NA
"low bq, low freq, many artifacts, many samples",UPN2_017,20,31022331,C,G,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg606Gly/c.1816C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),5537,70,5623,"0,0124488707",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,66",Neutral,222,Tolerated,"34,73","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_049,20,31022331,C,G,missense_variant(MODERATE|MISSENSE|Cgg/Ggg|p.Arg606Gly/c.1816C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9974,111,10107,"0,0109824874",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,66",Neutral,222,Tolerated,"34,92","18,14"
"low freq, many artifacts, many samples",UPN2_006,20,31022337,T,C,missense_variant(MODERATE|MISSENSE|Tgg/Cgg|p.Trp608Arg/c.1822T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3720,80,3805,"0,0210249671",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,91",Neutral,328,Tolerated,"35,24","35,3"
"low freq, many artifacts",UPN2_062,20,31022337,T,C,missense_variant(MODERATE|MISSENSE|Tgg/Cgg|p.Trp608Arg/c.1822T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),8800,93,9040,"0,0102876106",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,91",Neutral,328,Tolerated,"34,93","35,59"
"low freq, many artifacts, many samples",UPN2_001,20,31022337,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp608Gly/c.1822T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),6606,74,6723,"0,0110069909",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,21",Neutral,625,Tolerated,"35,06","34,41"
"low freq, many artifacts, many samples",UPN2_044,20,31022337,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp608Gly/c.1822T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3174,64,3249,"0,0196983687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,21",Neutral,625,Tolerated,"34,21","33,81"
"low freq, many artifacts, many samples",UPN2_045,20,31022337,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp608Gly/c.1822T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),15810,178,16094,"0,0110600224",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,21",Neutral,625,Tolerated,"34,37","33,12"
"low freq, many artifacts, many samples",UPN2_032,20,31022337,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp608Gly/c.1822T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),5112,58,5213,"0,0111260311",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,21",Neutral,625,Tolerated,"34,24","34,03"
"low freq, many artifacts, many samples",UPN2_007,20,31022337,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp608Gly/c.1822T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),19524,226,19916,"0,0113476602",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,21",Neutral,625,Tolerated,"35,1","34,59"
"low freq, many artifacts, many samples",UPN2_092,20,31022337,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp608Gly/c.1822T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3824,40,3903,"0,0102485268",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,21",Neutral,625,Tolerated,"34,75",36
"inspected, many samples, many artifacts",UPN2_061,20,31022337,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp608Gly/c.1822T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9204,103,9345,"0,0110219369",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,21",Neutral,"0,625",Tolerated,"35,11","34,82"
"many samples, low freq",UPN2_067,20,31022337,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp608Gly/c.1822T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9323,99,9494,"0,0104276385",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,21",Neutral,"0,625",Tolerated,"35,46","35,58"
"many samples, low freq",UPN2_070,20,31022337,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp608Gly/c.1822T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),7407,87,7533,"0,0115491836",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,21",Neutral,"0,625",Tolerated,"35,24","34,97"
"many samples, low freq",UPN2_073,20,31022337,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp608Gly/c.1822T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),6487,83,6627,"0,0125245209",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,21",Neutral,"0,625",Tolerated,"35,19","34,58"
"many samples, low freq",UPN2_076,20,31022337,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp608Gly/c.1822T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9079,135,9314,"0,0144943096",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,21",Neutral,"0,625",Tolerated,"35,29","35,17"
"low freq, many artifacts, many samples",UPN2_079,20,31022337,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp608Gly/c.1822T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),6658,68,6777,"0,0100339383",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,21",Neutral,625,Tolerated,"35,11","34,26"
"many samples, low freq",UPN2_082,20,31022337,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp608Gly/c.1822T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),10316,115,10494,"0,010958643",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,21",Neutral,"0,625",Tolerated,"35,29","34,32"
"many samples, low freq",UPN2_084,20,31022337,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp608Gly/c.1822T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),10057,114,10265,"0,011105699",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,21",Neutral,"0,625",Tolerated,"35,22","34,35"
"many samples, low freq",UPN2_085,20,31022337,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp608Gly/c.1822T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),7702,101,7870,"0,0128335451",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,21",Neutral,"0,625",Tolerated,"35,12","35,03"
"low freq, many artifacts",UPN2_102,20,31022337,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp608Gly/c.1822T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),7997,91,8138,"0,0111821086",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,21",Neutral,625,Tolerated,"34,35","34,13"
"low freq, many artifacts",UPN2_006,20,31022339,G,T,missense_variant(MODERATE|MISSENSE|tgG/tgT|p.Trp608Cys/c.1824G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3760,39,3804,"0,0102523659",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,62",Deleterious,47,Damaging,"32,08","31,54"
"low freq, many artifacts, many samples",UPN2_001,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),6582,97,6719,"0,0144366721",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"31,73",32
"low freq, many artifacts, many samples",UPN2_016,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),8696,98,8844,"0,0110809588",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"31,89","30,9"
"low freq, many artifacts, many samples",UPN2_020,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),8943,138,9167,"0,015053998",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"31,86","31,48"
"low freq, many artifacts, many samples",UPN2_002,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),8678,98,8827,"0,0111022998",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"31,79","31,63"
"low freq, many artifacts, many samples",UPN2_024,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),7153,79,7269,"0,0108680699",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"31,99","31,23"
"inspected, many samples, many artifacts",UPN2_042,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),19028,215,19492,"0,0110301662",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,"0,003",Damaging,"31,55","30,98"
"low freq, many artifacts, many samples",UPN2_029,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),15448,164,15727,"0,0104279265",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"32,01","31,12"
"low freq, many artifacts, many samples",UPN2_045,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),15736,203,16077,"0,0126267338",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"31,45","31,38"
"low freq, many artifacts, many samples",UPN2_046,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),18409,268,18910,"0,0141723956",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"31,55","31,33"
"low freq, many artifacts, many samples",UPN2_033,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),10861,140,11072,"0,0126445087",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"32,01","31,74"
"low freq, many artifacts, many samples",UPN2_034,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),4485,48,4567,"0,0105101817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"31,98","31,25"
"low freq, many artifacts, many samples",UPN2_036,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),11761,123,11931,"0,0103092784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"31,88","31,56"
"low freq, many artifacts, many samples",UPN2_049,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),10926,115,11145,"0,0103185285",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"31,46","30,75"
"many samples, low freq",UPN2_051,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),13742,170,14035,"0,0121125757",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,"0,003",Damaging,"31,58","30,54"
"low freq, many artifacts, many samples",UPN2_039,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),11724,135,11921,"0,0113245533",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"31,88","30,8"
"many samples, low freq",UPN2_054,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),10921,119,11127,"0,0106947066",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,"0,003",Damaging,"31,56","31,46"
"low freq, many artifacts, many samples",UPN2_007,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),19597,225,19888,"0,0113133548",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"31,68","31,52"
"many samples, low freq",UPN2_008,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),27551,340,28052,"0,0121203479",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,"0,003",Damaging,"31,72","31,48"
"low freq, many artifacts, many samples",UPN2_009,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),22700,314,23152,"0,0135625432",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"31,72","31,6"
"low freq, many artifacts, many samples",UPN2_011,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),16376,177,16633,"0,0106414958",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"31,7","31,69"
"low freq, many artifacts, many samples",UPN2_090,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),7042,76,7140,"0,0106442577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"31,84",32
"low freq, many artifacts, many samples",UPN2_012,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),8947,132,9152,"0,0144230769",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"31,69","30,77"
"low freq, many artifacts, many samples",UPN2_060,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),10084,139,10264,"0,0135424786",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"31,57","31,48"
"low freq, many artifacts, many samples",UPN2_063,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),9175,173,9438,"0,0183301547",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"31,55","31,69"
"low freq, many artifacts, many samples",UPN2_064,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),6992,109,7128,"0,015291807",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"31,59","31,34"
"low freq, many artifacts, many samples",UPN2_068,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),8653,160,8886,"0,0180058519",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"31,53","31,77"
"low freq, many artifacts, many samples",UPN2_069,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),10897,145,11131,"0,0130266822",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"31,55","31,63"
"low freq, many artifacts, many samples",UPN2_070,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),7349,100,7502,"0,0133297787",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"31,53",32
"low freq, many artifacts, many samples",UPN2_071,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),7359,125,7606,"0,0164343939",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"31,41","31,34"
"low freq, many artifacts, many samples",UPN2_073,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),6446,79,6584,"0,0119987849",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"31,51","31,41"
"low freq, many artifacts, many samples",UPN2_075,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),12217,165,12498,"0,0132021123",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"31,53","31,76"
"low freq, many artifacts, many samples",UPN2_077,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),9829,159,10097,"0,0157472517",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"31,52","31,77"
"low freq, many artifacts, many samples",UPN2_079,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),6624,85,6774,"0,0125479776",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"31,53","31,79"
"low freq, many artifacts, many samples",UPN2_080,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),9934,130,10159,"0,0127965351",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"31,49","31,17"
"low freq, many artifacts, many samples",UPN2_081,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),10566,116,10771,"0,0107696593",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"31,42","31,65"
"low freq, many artifacts, many samples",UPN2_082,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),10191,174,10449,"0,0166523112",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"31,57","31,59"
"low freq, many artifacts, many samples",UPN2_083,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),11071,143,11309,"0,0126447962",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"31,55","31,42"
many samples,UPN2_085,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),7599,182,7853,"0,0231758564",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"31,52","31,94"
"low freq, many artifacts, many samples",UPN2_086,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),5452,102,5594,"0,018233822",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"31,53","31,54"
"low freq, many artifacts, many samples",UPN2_088,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),8339,93,8479,"0,0109682746",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"31,54","31,23"
"many samples, low freq",UPN2_096,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),9221,107,9411,"0,0113696738",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,"0,003",Damaging,"31,72","31,28"
"low freq, many artifacts, many samples",UPN2_097,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),10347,138,10555,"0,0130743723",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"31,74","31,74"
"low freq, many artifacts, many samples",UPN2_101,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),6975,77,7110,"0,0108298172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"31,81","31,3"
"low freq, many artifacts, many samples",UPN2_102,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),7953,115,8123,"0,014157331",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"31,66","31,28"
"low freq, many artifacts, many samples",UPN2_105,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),8219,87,8367,"0,0103979921",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"31,75","30,97"
"low freq, many artifacts, many samples",UPN2_107,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),15007,184,15294,"0,0120308618",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"31,8","31,71"
"low freq, many artifacts, many samples",UPN2_110,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),12121,125,12329,"0,0101386974",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"31,74","30,99"
"low freq, many artifacts",UPN2_111,20,31022341,C,A,missense_variant(MODERATE|MISSENSE|aCt/aAt|p.Thr609Asn/c.1826C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),9868,137,10067,"0,0136088209",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,3,Damaging,"31,8","31,61"
"low bq, low freq, many artifacts",UPN2_041,20,31022341,C,G,missense_variant(MODERATE|MISSENSE|aCt/aGt|p.Thr609Ser/c.1826C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9435,109,9616,"0,0113352745",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,59",Deleterious,"0,14",Tolerated,"31,7","14,18"
"inspected, many artifacts, many samples",UPN2_012,20,31022343,G,A,missense_variant(MODERATE|MISSENSE|Ggc/Agc|p.Gly610Ser/c.1828G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),1470,30,1503,"0,0199600798",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,69",Deleterious,"0,044",Damaging,"34,65","32,1"
"low freq, many artifacts, many samples",UPN2_091,20,31022343,G,A,missense_variant(MODERATE|MISSENSE|Ggc/Agc|p.Gly610Ser/c.1828G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),1565,30,1601,"0,0187382886",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,69",Deleterious,44,Damaging,"33,53","31,63"
many samples,UPN2_061,20,31022343,G,A,missense_variant(MODERATE|MISSENSE|Ggc/Agc|p.Gly610Ser/c.1828G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),774,32,820,"0,0390243902",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,69",Deleterious,44,Damaging,"33,2","31,44"
"inspected, many artifacts, many samples",UPN2_062,20,31022343,G,A,missense_variant(MODERATE|MISSENSE|Ggc/Agc|p.Gly610Ser/c.1828G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),958,39,1000,"0,039",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,69",Deleterious,"0,044",Damaging,"33,17","32,33"
"inspected, many artifacts, many samples",UPN2_071,20,31022343,G,A,missense_variant(MODERATE|MISSENSE|Ggc/Agc|p.Gly610Ser/c.1828G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),1653,20,1690,"0,0118343195",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,69",Deleterious,"0,044",Damaging,"32,81","32,55"
"inspected, many artifacts",UPN2_044,20,31022346,G,A,missense_variant(MODERATE|MISSENSE|Gcc/Acc|p.Ala611Thr/c.1831G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),912,30,944,"0,031779661",0,0,0,0,1,1,0,1,3,"0,0116",NO,NO,NA,NA,NO,rs372418554,NO,"9,88E-005",NO,NO,"-3,32",Deleterious,"0,002",Damaging,"33,48","31,37"
"inspected, many artifacts",UPN2_041,20,31022346,G,T,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala611Ser/c.1831G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),9168,141,9417,"0,0149729213",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,48",Neutral,"0,009",Damaging,"33,59","30,56"
"low bq, many samples",UPN2_001,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),810,39,857,"0,0455075846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,18","15,59"
"low bq, many samples",UPN2_014,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4893,119,5039,"0,0236157968",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,17","15,03"
"low bq, many samples",UPN2_015,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),6788,199,7028,"0,0283153102",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,12","15,73"
"low bq, many samples",UPN2_016,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),2692,75,2783,"0,0269493352",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,26",15
"low bq, many samples",UPN2_017,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1678,100,1806,"0,0553709856",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"27,98","14,72"
"low bq, many samples",UPN2_018,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3132,100,3258,"0,0306936771",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,09","14,64"
"low bq, many samples",UPN2_019,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3843,106,3977,"0,0266532562",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,2","15,58"
"low bq, many samples",UPN2_020,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),2894,77,2998,"0,0256837892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,42","14,4"
"low bq, many samples",UPN2_021,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3309,81,3407,"0,0237745817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"27,98","15,31"
"low bq, many samples",UPN2_002,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1333,39,1386,"0,0281385281",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"29,18","16,56"
"low bq, many samples",UPN2_022,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5175,142,5355,"0,0265172736",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,25","15,73"
"low bq, many samples",UPN2_023,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5751,161,5941,"0,0270998148",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,08","15,67"
"low bq, many samples",UPN2_041,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),9041,310,9418,"0,0329156934",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,67","15,87"
"low bq, many samples",UPN2_024,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),2595,60,2676,"0,0224215247",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,03","16,65"
"low bq, many samples",UPN2_025,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5496,221,5773,"0,038281656",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"27,83","15,62"
"low bq, many samples",UPN2_026,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5638,133,5817,"0,0228640193",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,09","15,43"
"low bq, many samples",UPN2_027,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5865,164,6077,"0,0269870002",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,3","15,62"
"low bq, many samples",UPN2_042,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5546,166,5755,"0,0288444831",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,72","16,53"
"low bq, many samples",UPN2_028,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3985,107,4119,"0,0259771789",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,05","16,39"
"low bq, many samples",UPN2_043,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3559,118,3701,"0,0318832748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,5","15,44"
"low bq, many samples",UPN2_044,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),898,38,944,"0,0402542373",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,52","15,05"
"low bq, many samples",UPN2_029,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5251,153,5451,"0,0280682444",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,19","15,91"
"low bq, many samples",UPN2_030,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5441,149,5627,"0,026479474",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,05","15,69"
"low bq, many samples",UPN2_031,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3500,100,3636,"0,0275027503",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"27,78","15,1"
"low bq, many samples",UPN2_045,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3823,173,4037,"0,0428536042",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,06","16,5"
"low bq, many samples",UPN2_032,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1602,49,1663,"0,0294648226",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"27,95","15,9"
"low bq, many samples",UPN2_046,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),6102,205,6363,"0,0322175075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,55","17,11"
"low bq, many samples",UPN2_033,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3718,113,3854,"0,0293201868",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,12","16,07"
"low bq, many samples",UPN2_034,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1631,43,1692,"0,0254137116",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,23","15,02"
"low bq, many samples",UPN2_047,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),7998,254,8352,"0,0304118774",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,54","16,68"
"low bq, many samples",UPN2_048,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),7141,230,7421,"0,0309931276",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,46","15,67"
"low bq, many samples",UPN2_035,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4287,125,4431,"0,0282103363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"27,84","16,72"
"low bq, many samples",UPN2_036,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3947,129,4124,"0,0312803104",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"27,84","15,46"
"low bq, many samples",UPN2_049,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),2855,148,3028,"0,0488771466",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,52","15,49"
"low bq, many samples",UPN2_050,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4427,126,4608,"0,02734375",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,46","15,92"
"low bq, many samples",UPN2_037,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),7917,205,8170,"0,0250917993",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,09",15
"low bq, many samples",UPN2_051,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4415,168,4621,"0,0363557671",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,6","16,02"
"low bq, many samples",UPN2_052,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3922,122,4079,"0,0299092915",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,53","15,42"
"low bq, many samples",UPN2_038,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),8687,250,8996,"0,0277901289",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,03","16,8"
"low bq, many samples",UPN2_039,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4410,146,4597,"0,0317598434",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"27,66","15,57"
"low bq, many samples",UPN2_053,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5778,195,6011,"0,0324405257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,61","15,51"
"low bq, many samples",UPN2_054,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3134,131,3292,"0,0397934386",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,42","16,66"
"low bq, many samples",UPN2_007,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),2328,69,2412,"0,0286069652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,69","15,42"
"low bq, many samples",UPN2_008,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4209,122,4360,"0,0279816514",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,89","15,58"
"low bq, many samples",UPN2_009,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3556,96,3689,"0,0260233126",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"29,11","15,61"
"low bq, many samples",UPN2_010,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1829,58,1905,"0,0304461942",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"29,19","15,53"
"low bq, many samples",UPN2_011,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1754,70,1838,"0,0380848749",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,91","15,51"
"low bq, many samples",UPN2_055,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5885,181,6104,"0,0296526868",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,64","16,38"
"low bq, many samples",UPN2_056,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),924,36,963,"0,0373831776",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,65","16,22"
"low bq, many samples",UPN2_057,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4044,137,4192,"0,0326812977",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,64","15,75"
"low bq, many samples",UPN2_058,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),8073,284,8421,"0,0337252108",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,47","16,26"
"low bq, many samples",UPN2_012,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1420,48,1476,"0,0325203252",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,7","14,83"
"low bq, many samples",UPN2_040,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4043,142,4218,"0,0336652442",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"27,93","15,19"
"low bq, many samples",UPN2_013,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),975,29,1009,"0,028741328",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"28,83","16,62"
"low bq, low freq, many artifacts, many samples",UPN2_071,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1637,24,1675,"0,0143283582",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"29,58",14
"low bq, low freq, many artifacts, many samples",UPN2_075,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1451,29,1486,"0,0195154778",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"29,27","15,07"
"low bq, many samples",UPN2_078,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1159,28,1198,"0,0233722871",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"29,55","17,93"
"low bq, low freq, many artifacts, many samples",UPN2_080,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1258,22,1291,"0,0170410534",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"29,7","18,23"
"low bq, low freq, many artifacts, many samples",UPN2_081,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1935,25,1974,"0,0126646403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"29,42","16,48"
"low bq, low freq, many artifacts, many samples",UPN2_094,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3344,35,3389,"0,0103275302",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"30,19","16,14"
"low bq, low freq, many artifacts, many samples",UPN2_102,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),2243,26,2278,"0,0114135206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"30,01",14
"low bq, low freq, many artifacts, many samples",UPN2_104,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3027,50,3096,"0,0161498708",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"29,79","14,44"
"low bq, low freq, many artifacts",UPN2_108,20,31022349,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg612Trp/c.1834A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4163,60,4242,"0,0141442716",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,78",Deleterious,0,Damaging,"29,95",14
"low bq, low freq, many artifacts",UPN2_081,20,31022352,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr613Pro/c.1837A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1942,21,1974,"0,0106382979",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,85",Deleterious,28,Damaging,31,"14,86"
"low bq, low freq, many artifacts, many samples",UPN2_071,20,31022355,C,G,missense_variant(MODERATE|MISSENSE|Ctc/Gtc|p.Leu614Val/c.1840C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),1651,21,1676,"0,0125298329",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,39",Neutral,3,Damaging,"30,75",14
"low bq, low freq, many artifacts, many samples",UPN2_081,20,31022355,C,G,missense_variant(MODERATE|MISSENSE|Ctc/Gtc|p.Leu614Val/c.1840C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),1947,22,1975,"0,0111392405",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,39",Neutral,3,Damaging,"31,04","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_045,20,31022361,G,T,missense_variant(MODERATE|MISSENSE|Gac/Tac|p.Asp616Tyr/c.1846G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3974,59,4040,"0,0146039604",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,83",Deleterious,0,Damaging,"31,98",14
"low bq, low freq, many artifacts, many samples",UPN2_046,20,31022361,G,T,missense_variant(MODERATE|MISSENSE|Gac/Tac|p.Asp616Tyr/c.1846G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),6281,75,6367,"0,011779488",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,83",Deleterious,0,Damaging,"32,49","21,35"
"low bq, low freq, many artifacts",UPN2_049,20,31022361,G,T,missense_variant(MODERATE|MISSENSE|Gac/Tac|p.Asp616Tyr/c.1846G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),2993,36,3035,"0,0118616145",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,83",Deleterious,0,Damaging,"32,29","14,61"
"low bq, low freq, many artifacts",UPN2_055,20,31022362,A,T,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp616Val/c.1847A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),6015,63,6112,"0,0103075916",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,83",Deleterious,0,Damaging,"31,18","17,92"
"inspected, many artifacts",UPN2_090,20,31022362,A,T,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp616Val/c.1847A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1670,21,1698,"0,0123674912",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,83",Deleterious,0,Damaging,"31,36","28,05"
"low bq, low freq, many artifacts",UPN2_049,20,31022363,C,A,missense_variant(MODERATE|MISSENSE|gaC/gaA|p.Asp616Glu/c.1848C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),2992,40,3035,"0,0131795717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,1,Damaging,"31,39","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_014,20,31022364,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile617Phe/c.1849A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4962,51,5042,"0,0101150337",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,65,Tolerated,"32,88","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_015,20,31022364,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile617Phe/c.1849A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),6911,113,7031,"0,0160716825",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,65,Tolerated,"32,9","18,41"
"low bq, low freq, many artifacts, many samples",UPN2_016,20,31022364,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile617Phe/c.1849A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),2745,28,2783,"0,0100610852",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,65,Tolerated,"32,78","15,68"
"low bq, low freq, many artifacts, many samples",UPN2_018,20,31022364,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile617Phe/c.1849A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3201,50,3259,"0,0153421295",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,65,Tolerated,"32,92","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_019,20,31022364,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile617Phe/c.1849A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3914,47,3979,"0,0118120131",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,65,Tolerated,"32,86","15,49"
"low bq, low freq, many artifacts, many samples",UPN2_020,20,31022364,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile617Phe/c.1849A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),2964,34,3000,"0,0113333333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,65,Tolerated,"32,84","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_021,20,31022364,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile617Phe/c.1849A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3360,42,3408,"0,0123239437",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,65,Tolerated,"32,7","18,1"
"low bq, low freq, many artifacts, many samples",UPN2_022,20,31022364,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile617Phe/c.1849A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5270,64,5358,"0,0119447555",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,65,Tolerated,"32,85","17,31"
"low bq, low freq, many artifacts, many samples",UPN2_023,20,31022364,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile617Phe/c.1849A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5858,71,5945,"0,0119428091",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,65,Tolerated,"32,75","16,82"
"low bq, low freq, many artifacts, many samples",UPN2_041,20,31022364,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile617Phe/c.1849A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),9238,151,9428,"0,0160161222",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,65,Tolerated,"32,1","15,78"
"low bq, low freq, many artifacts, many samples",UPN2_025,20,31022364,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile617Phe/c.1849A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5664,85,5779,"0,0147084271",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,65,Tolerated,"32,4",17
"low bq, low freq, many artifacts, many samples",UPN2_026,20,31022364,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile617Phe/c.1849A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5738,61,5821,"0,0104792991",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,65,Tolerated,"32,84","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_042,20,31022364,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile617Phe/c.1849A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5619,107,5763,"0,0185667187",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,65,Tolerated,"32,3","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_043,20,31022364,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile617Phe/c.1849A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3645,56,3708,"0,0151024811",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,65,Tolerated,"32,03","15,34"
"low bq, low freq, many artifacts, many samples",UPN2_029,20,31022364,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile617Phe/c.1849A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5373,62,5452,"0,0113719736",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,65,Tolerated,"32,78","15,71"
"low bq, low freq, many artifacts, many samples",UPN2_031,20,31022364,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile617Phe/c.1849A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3580,47,3637,"0,0129227385",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,65,Tolerated,"32,49","17,47"
"low bq, low freq, many artifacts, many samples",UPN2_045,20,31022364,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile617Phe/c.1849A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3952,84,4042,"0,0207817912",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,65,Tolerated,"31,68","15,85"
"low bq, low freq, many artifacts, many samples",UPN2_046,20,31022364,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile617Phe/c.1849A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),6238,116,6374,"0,0181989332",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,65,Tolerated,"32,01","15,93"
"low bq, low freq, many artifacts, many samples",UPN2_033,20,31022364,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile617Phe/c.1849A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3793,44,3856,"0,0114107884",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,65,Tolerated,"32,74","16,41"
"low bq, low freq, many artifacts, many samples",UPN2_047,20,31022364,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile617Phe/c.1849A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),8193,127,8363,"0,0151859381",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,65,Tolerated,"32,04","15,46"
"low bq, low freq, many artifacts, many samples",UPN2_048,20,31022364,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile617Phe/c.1849A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),7252,126,7431,"0,0169559952",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,65,Tolerated,"32,12","16,99"
"low bq, low freq, many artifacts, many samples",UPN2_035,20,31022364,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile617Phe/c.1849A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4353,57,4434,"0,0128552097",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,65,Tolerated,"32,85","15,35"
"low bq, many samples",UPN2_049,20,31022364,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile617Phe/c.1849A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),2961,69,3035,"0,0227347611",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,65,Tolerated,"31,78","16,75"
"low bq, low freq, many artifacts, many samples",UPN2_050,20,31022364,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile617Phe/c.1849A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4512,64,4617,"0,013861815",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,65,Tolerated,"32,16","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_037,20,31022364,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile617Phe/c.1849A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),8060,94,8176,"0,0114970646",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,65,Tolerated,"32,86","17,24"
"low bq, low freq, many artifacts, many samples",UPN2_051,20,31022364,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile617Phe/c.1849A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4535,76,4627,"0,0164253296",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,65,Tolerated,"32,16","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_052,20,31022364,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile617Phe/c.1849A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3998,64,4081,"0,0156824308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,65,Tolerated,"32,23","15,69"
"low bq, low freq, many artifacts, many samples",UPN2_038,20,31022364,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile617Phe/c.1849A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),8846,119,9004,"0,0132163483",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,65,Tolerated,"32,83","15,96"
"low bq, low freq, many artifacts, many samples",UPN2_039,20,31022364,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile617Phe/c.1849A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4527,51,4598,"0,011091779",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,65,Tolerated,"32,4","15,73"
"low bq, low freq, many artifacts, many samples",UPN2_053,20,31022364,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile617Phe/c.1849A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5900,90,6021,"0,0149476831",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,65,Tolerated,"32,23","15,49"
"low bq, low freq, many artifacts, many samples",UPN2_054,20,31022364,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile617Phe/c.1849A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3252,38,3296,"0,0115291262",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,65,Tolerated,"31,98","15,95"
"low bq, low freq, many artifacts, many samples",UPN2_007,20,31022364,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile617Phe/c.1849A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),2375,33,2412,"0,013681592",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,65,Tolerated,"33,14","16,27"
"low bq, low freq, many artifacts, many samples",UPN2_009,20,31022364,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile617Phe/c.1849A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3642,40,3691,"0,0108371715",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,65,Tolerated,"33,21","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_011,20,31022364,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile617Phe/c.1849A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1812,25,1839,"0,0135943448",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,65,Tolerated,"32,88","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_055,20,31022364,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile617Phe/c.1849A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5993,87,6112,"0,0142342932",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,65,Tolerated,"32,19","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_057,20,31022364,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile617Phe/c.1849A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4115,77,4199,"0,0183376995",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,65,Tolerated,"32,11","16,22"
"low bq, low freq, many artifacts, many samples",UPN2_058,20,31022364,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile617Phe/c.1849A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),8240,161,8431,"0,0190961926",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,65,Tolerated,"32,16","15,56"
"low bq, low freq, many artifacts, many samples",UPN2_040,20,31022364,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile617Phe/c.1849A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4149,46,4220,"0,0109004739",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,65,Tolerated,"32,48","15,63"
"low bq, low freq, many artifacts",UPN2_071,20,31022364,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile617Phe/c.1849A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1647,22,1676,"0,0131264916",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,65,Tolerated,"32,48","16,95"
"low bq, low freq, many artifacts, many samples",UPN2_043,20,31022368,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys618Ile/c.1853A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3638,47,3709,"0,0126718792",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,0,Damaging,"32,56","20,11"
"low bq, low freq, many artifacts, many samples",UPN2_049,20,31022368,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys618Ile/c.1853A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),2987,35,3042,"0,0115055884",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,0,Damaging,"32,32","21,03"
"low bq, low freq, many artifacts, many samples",UPN2_052,20,31022368,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys618Ile/c.1853A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4002,57,4085,"0,0139534884",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,87",Deleterious,0,Damaging,"32,45","22,05"
"low bq, many samples",UPN2_001,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),824,24,858,"0,027972028",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"28,31",14
"low bq, low freq, many artifacts, many samples",UPN2_014,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4899,59,5042,"0,0117017057",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"28,94",14
"low bq, low freq, many artifacts, many samples",UPN2_015,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6816,106,7032,"0,0150739477",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"28,88",15
"low bq, low freq, many artifacts, many samples",UPN2_016,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),2700,36,2784,"0,0129310345",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"29,08",14
"low bq, many samples",UPN2_017,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1716,52,1806,"0,0287929125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"28,47",14
"low bq, low freq, many artifacts, many samples",UPN2_018,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3156,53,3260,"0,0162576687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"29,16","14,13"
"low bq, low freq, many artifacts, many samples",UPN2_019,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3868,55,3979,"0,0138225685",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"29,03","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_020,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),2896,51,3000,"0,017",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"29,18","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_021,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3315,49,3410,"0,0143695015",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"29,27","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_022,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),5203,78,5360,"0,0145522388",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"29,15","14,09"
"low bq, low freq, many artifacts, many samples",UPN2_023,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),5754,82,5945,"0,0137931034",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"29,13","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_041,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),9110,125,9432,"0,0132527566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"29,46","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_024,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),2603,31,2678,"0,0115758028",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"29,05","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_025,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),5556,121,5781,"0,0209306348",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"28,75","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_026,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),5657,80,5823,"0,0137386227",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"29,1",14
"low bq, low freq, many artifacts, many samples",UPN2_027,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),5903,73,6081,"0,0120046045",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"28,95","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_042,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),5568,69,5771,"0,0119563334",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"29,46","14,1"
"low bq, low freq, many artifacts, many samples",UPN2_028,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3987,62,4120,"0,0150485437",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"28,86","14,11"
"low bq, low freq, many artifacts, many samples",UPN2_043,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3573,52,3710,"0,0140161725",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"29,46","14,13"
"low bq, low freq, many artifacts, many samples",UPN2_029,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),5289,81,5453,"0,0148542087",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"29,15","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_030,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),5471,74,5631,"0,0131415379",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"29,01",14
"low bq, low freq, many artifacts, many samples",UPN2_031,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3517,57,3639,"0,0156636439",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"28,88",14
"low bq, low freq, many artifacts, many samples",UPN2_045,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3859,74,4045,"0,0182941904",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"28,75","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_046,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6148,96,6377,"0,0150541007",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"29,3","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_033,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3712,53,3858,"0,0137376879",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"29,23","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_034,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1637,30,1695,"0,017699115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"28,93","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_047,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),8046,118,8376,"0,0140878701",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"29,44","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_048,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),7159,111,7434,"0,0149313963",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"29,33","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_035,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4294,68,4436,"0,0153291253",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"29,06","14,75"
"low bq, many samples",UPN2_036,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3974,97,4131,"0,0234809973",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"28,62","14,26"
"low bq, many samples",UPN2_049,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),2903,70,3042,"0,0230111769",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"28,89",14
"low bq, low freq, many artifacts, many samples",UPN2_050,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4464,67,4626,"0,014483355",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"29,32","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_037,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),7921,124,8176,"0,0151663405",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"28,96","14,06"
"low bq, low freq, many artifacts, many samples",UPN2_051,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4458,63,4629,"0,0136098509",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"29,51","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_052,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3954,60,4085,"0,0146878825",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"29,34","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_038,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),8715,124,9006,"0,0137685987",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"28,9","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_039,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4449,69,4598,"0,0150065246",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"28,6","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_053,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),5796,83,6029,"0,0137667938",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"29,3","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_054,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3174,53,3297,"0,0160752199",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"29,15","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_007,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),2290,39,2421,"0,0161090458",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"29,45","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_008,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4227,67,4365,"0,01534937",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"29,07","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_009,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3572,64,3694,"0,0173253925",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"29,48",14
"low bq, low freq, many artifacts, many samples",UPN2_010,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1848,28,1907,"0,0146827478",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"29,26","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_011,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1773,29,1839,"0,0157694399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"29,35",14
"low bq, low freq, many artifacts, many samples",UPN2_055,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),5887,78,6115,"0,0127555192",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"29,54","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_057,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4040,56,4202,"0,0133269871",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"29,42",14
"low bq, low freq, many artifacts, many samples",UPN2_058,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),8136,103,8433,"0,0122139215",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"29,34","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_012,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1414,26,1477,"0,0176032498",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"29,53","16,19"
"low bq, low freq, many artifacts, many samples",UPN2_040,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4056,82,4220,"0,0194312796",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"28,57","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_071,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1622,33,1677,"0,0196779964",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"29,27","15,94"
"low bq, low freq, many artifacts, many samples",UPN2_078,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1162,24,1199,"0,0200166806",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"29,37","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_081,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1928,37,1976,"0,0187246964",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"29,55","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_104,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),2994,68,3099,"0,0219425621",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"31,07",14
"low bq, low freq, many artifacts",UPN2_108,20,31022369,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys618Asn/c.1854A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4159,43,4248,"0,0101224105",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"31,53","15,35"
"low bq, low freq, many artifacts",UPN2_056,20,31022369,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys618Asn/c.1854A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),927,20,964,"0,020746888",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,29",Deleterious,1,Damaging,"29,12","17,3"
"low bq, low freq, many artifacts, many samples",UPN2_017,20,31022373,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg620Gly/c.1858C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),1776,21,1808,"0,0116150442",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,08",Deleterious,4,Damaging,"29,52",14
"low bq, low freq, many artifacts, many samples",UPN2_041,20,31022373,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg620Gly/c.1858C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9278,100,9432,"0,0106022053",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,08",Deleterious,4,Damaging,"30,56","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_045,20,31022373,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg620Gly/c.1858C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3977,52,4047,"0,012849024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,08",Deleterious,4,Damaging,"30,15","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_047,20,31022373,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg620Gly/c.1858C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),8232,84,8379,"0,0100250627",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,08",Deleterious,4,Damaging,"30,62","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_048,20,31022373,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg620Gly/c.1858C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),7331,84,7440,"0,0112903226",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,08",Deleterious,4,Damaging,"30,58","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_049,20,31022373,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg620Gly/c.1858C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),2987,44,3043,"0,0144594151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,08",Deleterious,4,Damaging,"30,06",14
"low bq, low freq, many artifacts, many samples",UPN2_052,20,31022373,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg620Gly/c.1858C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),4025,41,4089,"0,0100269014",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,08",Deleterious,4,Damaging,"30,69",14
"low bq, low freq, many artifacts, many samples",UPN2_054,20,31022373,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg620Gly/c.1858C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3247,41,3301,"0,0124204786",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,08",Deleterious,4,Damaging,"30,45",14
"low bq, low freq, many artifacts, many samples",UPN2_058,20,31022373,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg620Gly/c.1858C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),8306,108,8441,"0,0127946926",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,08",Deleterious,4,Damaging,"30,39","14,19"
"low bq, low freq, many artifacts",UPN2_104,20,31022373,C,G,missense_variant(MODERATE|MISSENSE|Cgt/Ggt|p.Arg620Gly/c.1858C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3042,53,3100,"0,0170967742",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,08",Deleterious,4,Damaging,"29,92","14,13"
"low freq, bad alignment, many artifacts",UPN2_081,20,31022373,C,T,missense_variant(MODERATE|MISSENSE|Cgt/Tgt|p.Arg620Cys/c.1858C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1928,37,1976,"0,0187246964",0,0,0,0,1,1,0,1,3,NO,0,NO,NA,NA,NO,NO,NO,"0,0001483",NO,NO,"-5,31",Deleterious,"0,084",Tolerated,"30,3","32,22"
"inspected, many artifacts",UPN2_093,20,31022377,C,T,missense_variant(MODERATE|MISSENSE|gCt/gTt|p.Ala621Val/c.1862C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1296,20,1321,"0,0151400454",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,44",Deleterious,"0,001",Damaging,"32,33","32,5"
"inspected, many artifacts, bad alignment",UPN2_011,20,31022382,CA,C,frameshift_variant(HIGH||cag/|p.Gln623fs/c.1868delA|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1746,36,1839,"0,0195758564",0,0,0,1,1,0,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,59",NA
"inspected, many artifacts, bad alignment",UPN2_045,20,31022383,A,G,missense_variant(MODERATE|MISSENSE|cAg/cGg|p.Gln623Arg/c.1868A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3853,45,4051,"0,0111083683",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,71",Deleterious,"0,003",Damaging,"31,15","31,89"
"low bq, many samples",UPN2_001,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),825,27,858,"0,0314685315",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"31,5",14
"low bq, many samples",UPN2_014,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4887,125,5044,"0,0247819191",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"31,87","14,83"
"low bq, many samples",UPN2_015,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),6814,186,7033,"0,026446751",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"31,9","16,62"
"low bq, many samples",UPN2_016,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),2694,77,2786,"0,027638191",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,32,"15,43"
"low bq, many samples",UPN2_017,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1683,104,1805,"0,0576177285",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"31,2","15,49"
"low bq, many samples",UPN2_018,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3146,99,3262,"0,0303494788",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"31,64","16,78"
"low bq, many samples",UPN2_019,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3861,94,3979,"0,0236240261",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"32,12","16,56"
"low bq, many samples",UPN2_020,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),2921,66,3000,"0,022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"32,06","16,91"
"low bq, low freq, many artifacts, many samples",UPN2_021,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3329,71,3413,"0,0208028128",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"31,88","15,11"
"low bq, many samples",UPN2_002,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1338,32,1387,"0,0230713771",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"31,94",14
"low bq, many samples",UPN2_022,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5209,121,5362,"0,0225662066",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"32,06","16,72"
"low bq, many samples",UPN2_023,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5766,134,5945,"0,0225399495",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"31,83","15,86"
"low bq, many samples",UPN2_041,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),9111,272,9445,"0,028798306",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"31,75","16,32"
"low bq, many samples",UPN2_024,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),2596,65,2680,"0,0242537313",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"32,01","17,48"
"low bq, many samples",UPN2_025,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5565,187,5782,"0,0323417503",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"31,14","15,7"
"low bq, many samples",UPN2_026,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5652,132,5825,"0,0226609442",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"31,93","16,14"
"low bq, low freq, many artifacts, many samples",UPN2_027,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5921,127,6083,"0,0208778563",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"31,95","16,1"
"low bq, many samples",UPN2_042,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5595,148,5781,"0,0256011071",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"31,65","16,81"
"low bq, low freq, many artifacts, many samples",UPN2_028,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4014,89,4121,"0,0215966998",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"31,89","15,57"
"low bq, many samples",UPN2_043,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3575,121,3716,"0,0325618945",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"31,77","17,24"
"low bq, many samples",UPN2_044,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),915,26,948,"0,0274261603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"31,95","14,69"
"low bq, many samples",UPN2_029,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5265,146,5455,"0,0267644363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"32,03","17,73"
"low bq, many samples",UPN2_030,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5459,142,5635,"0,0251996451",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"32,09","17,25"
"low bq, many samples",UPN2_031,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3531,94,3642,"0,0258099945",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"31,53","16,19"
"low bq, low freq, many artifacts, many samples",UPN2_032,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1625,26,1663,"0,0156343957",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"31,75","18,27"
"low bq, many samples",UPN2_046,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),6152,206,6389,"0,0322429175",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"31,78","15,86"
"low bq, many samples",UPN2_033,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3736,109,3860,"0,028238342",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"32,01","16,37"
"low bq, many samples",UPN2_034,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1640,44,1696,"0,0259433962",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"31,85","15,75"
"low bq, many samples",UPN2_047,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),8096,246,8387,"0,0293311077",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"31,78","16,9"
"low bq, many samples",UPN2_048,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),7170,223,7443,"0,0299610372",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"31,56","16,45"
"low bq, many samples",UPN2_035,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4308,116,4437,"0,0261437908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"31,72","15,95"
"low bq, many samples",UPN2_036,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3969,143,4129,"0,0346330831",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"31,58","16,03"
"low bq, many samples",UPN2_049,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),2867,161,3041,"0,0529431108",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"31,48","17,65"
"low bq, many samples",UPN2_050,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4486,122,4633,"0,0263328297",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"31,54","15,81"
"low bq, low freq, many artifacts, many samples",UPN2_037,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),7968,173,8182,"0,0211439746",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"31,84","15,42"
"low bq, many samples",UPN2_051,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4455,149,4632,"0,0321675302",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"31,84","17,62"
"low bq, many samples",UPN2_052,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3941,120,4091,"0,0293326815",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"31,76","15,97"
"low bq, many samples",UPN2_038,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),8716,247,9010,"0,0274139845",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"31,9","16,58"
"low bq, many samples",UPN2_039,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4430,124,4600,"0,0269565217",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"31,49","15,74"
"low bq, many samples",UPN2_053,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5811,184,6038,"0,0304736668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"31,8","17,16"
"low bq, many samples",UPN2_054,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3203,81,3302,"0,0245305875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"31,71","16,79"
"low bq, many samples",UPN2_007,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),2351,66,2426,"0,0272052762",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"31,89","16,24"
"low bq, many samples",UPN2_008,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4249,102,4361,"0,0233891309",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"31,87","16,17"
"low bq, many samples",UPN2_009,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3591,89,3695,"0,0240866035",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"32,08","15,85"
"low bq, low freq, many artifacts, many samples",UPN2_010,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1869,35,1908,"0,0183438155",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"31,75","15,14"
"low bq, many samples",UPN2_055,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5923,154,6122,"0,025155178",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"31,84","15,77"
"low bq, many samples",UPN2_057,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4054,118,4206,"0,0280551593",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"31,83","15,88"
"low bq, many samples",UPN2_058,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),8175,231,8447,"0,0273469871",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"31,61","16,41"
"low bq, many samples",UPN2_012,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1426,46,1476,"0,0311653117",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"31,64","15,39"
"low bq, many samples",UPN2_040,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4070,133,4221,"0,0315091211",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"31,58","16,23"
"low bq, low freq, many artifacts, many samples",UPN2_071,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1651,21,1679,"0,0125074449",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"32,35","16,1"
"low bq, low freq, many artifacts, many samples",UPN2_097,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3116,33,3158,"0,0104496517",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"33,37","16,7"
"low bq, low freq, many artifacts, many samples",UPN2_104,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3020,64,3097,"0,0206651598",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"32,69","15,03"
"low bq, low freq, many artifacts",UPN2_108,20,31022383,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln623Leu/c.1868A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4152,73,4244,"0,017200754",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,97,Tolerated,"33,32","15,51"
"low bq, low freq, many artifacts, many samples",UPN2_043,20,31022386,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val624Gly/c.1871T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3661,41,3716,"0,0110333692",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,4",Neutral,"0,34",Tolerated,"30,5","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_045,20,31022386,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val624Gly/c.1871T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3985,48,4052,"0,011846002",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,4",Neutral,"0,34",Tolerated,"29,98",14
"low bq, low freq, many artifacts, many samples",UPN2_052,20,31022386,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val624Gly/c.1871T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),4027,45,4092,"0,0109970674",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,4",Neutral,"0,34",Tolerated,"30,51","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_055,20,31022386,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val624Gly/c.1871T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),6022,62,6122,"0,0101274093",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,4",Neutral,"0,34",Tolerated,"30,53","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_040,20,31022386,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val624Gly/c.1871T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),4161,43,4222,"0,0101847466",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,4",Neutral,"0,34",Tolerated,"29,84","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_071,20,31022386,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val624Gly/c.1871T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),1640,30,1678,"0,0178784267",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,4",Neutral,"0,34",Tolerated,"30,02","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_075,20,31022386,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val624Gly/c.1871T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),1463,20,1487,"0,0134498991",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,4",Neutral,"0,34",Tolerated,"30,47",14
"low bq, low freq, many artifacts",UPN2_081,20,31022386,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val624Gly/c.1871T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),1939,28,1977,"0,014162873",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,4",Neutral,"0,34",Tolerated,"30,09",14
"low bq, low freq, many artifacts, many samples",UPN2_041,20,31022388,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg625Gly/c.1873C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9314,98,9449,"0,0103714679",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"31,14","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_024,20,31022388,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg625Gly/c.1873C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),2640,28,2679,"0,0104516611",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"31,34","18,04"
"low bq, low freq, many artifacts, many samples",UPN2_042,20,31022388,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg625Gly/c.1873C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),5682,58,5783,"0,0100293965",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"31,21","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_045,20,31022388,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg625Gly/c.1873C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3981,57,4053,"0,0140636566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"30,82","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_046,20,31022388,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg625Gly/c.1873C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),6305,66,6395,"0,0103205629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"31,14","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_034,20,31022388,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg625Gly/c.1873C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),1673,20,1696,"0,0117924528",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"31,35",14
"low bq, low freq, many artifacts, many samples",UPN2_047,20,31022388,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg625Gly/c.1873C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),8266,88,8391,"0,010487427",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"31,14","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_048,20,31022388,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg625Gly/c.1873C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),7327,78,7443,"0,0104796453",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"31,21","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_049,20,31022388,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg625Gly/c.1873C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),2995,39,3040,"0,0128289474",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"30,54","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_051,20,31022388,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg625Gly/c.1873C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),4567,51,4633,"0,0110079862",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"31,28","16,04"
"low bq, low freq, many artifacts, many samples",UPN2_052,20,31022388,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg625Gly/c.1873C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),4019,47,4092,"0,011485826",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"31,35","14,15"
"low bq, low freq, many artifacts, many samples",UPN2_053,20,31022388,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg625Gly/c.1873C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),5947,64,6037,"0,010601292",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"31,31","14,69"
"low bq, low freq, many artifacts",UPN2_054,20,31022388,C,G,missense_variant(MODERATE|MISSENSE|Cga/Gga|p.Arg625Gly/c.1873C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3256,34,3304,"0,0102905569",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,1,Damaging,"31,34","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_025,20,31022395,C,G,missense_variant(MODERATE|MISSENSE|gCg/gGg|p.Ala627Gly/c.1880C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),5690,71,5781,"0,0122816122",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,02",Neutral,26,Damaging,"30,14","14,18"
"low bq, low freq, many artifacts, many samples",UPN2_045,20,31022395,C,G,missense_variant(MODERATE|MISSENSE|gCg/gGg|p.Ala627Gly/c.1880C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3973,56,4055,"0,013810111",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,02",Neutral,26,Damaging,"30,1","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_034,20,31022395,C,G,missense_variant(MODERATE|MISSENSE|gCg/gGg|p.Ala627Gly/c.1880C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),1656,21,1697,"0,012374779",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,02",Neutral,26,Damaging,"30,97","16,95"
"low bq, low freq, many artifacts, many samples",UPN2_036,20,31022395,C,G,missense_variant(MODERATE|MISSENSE|gCg/gGg|p.Ala627Gly/c.1880C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),4077,47,4129,"0,0113829014",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,02",Neutral,26,Damaging,"30,43","16,28"
"low bq, low freq, many artifacts, many samples",UPN2_049,20,31022395,C,G,missense_variant(MODERATE|MISSENSE|gCg/gGg|p.Ala627Gly/c.1880C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),2988,35,3039,"0,0115169464",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,02",Neutral,26,Damaging,"30,25","16,77"
"low bq, low freq, many artifacts, many samples",UPN2_052,20,31022395,C,G,missense_variant(MODERATE|MISSENSE|gCg/gGg|p.Ala627Gly/c.1880C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),4027,52,4093,"0,0127046176",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,02",Neutral,26,Damaging,"31,04","20,37"
"low bq, low freq, many artifacts, many samples",UPN2_039,20,31022395,C,G,missense_variant(MODERATE|MISSENSE|gCg/gGg|p.Ala627Gly/c.1880C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),4528,56,4602,"0,0121686223",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,02",Neutral,26,Damaging,"30,55",14
"low bq, low freq, many artifacts",UPN2_104,20,31022395,C,G,missense_variant(MODERATE|MISSENSE|gCg/gGg|p.Ala627Gly/c.1880C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3052,31,3093,"0,0100226317",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,02",Neutral,26,Damaging,"31,13",14
"inspected, many artifacts, bad alignment",UPN2_011,20,31022395,C,T,missense_variant(MODERATE|MISSENSE|gCg/gTg|p.Ala627Val/c.1880C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1778,55,1839,"0,0299075585",0,0,0,0,1,1,0,1,3,NO,NO,COSM4097553,stomach,1,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,"0,015",Damaging,"31,61","27,89"
"low freq, bad alignment, many artifacts",UPN2_081,20,31022395,C,T,missense_variant(MODERATE|MISSENSE|gCg/gTg|p.Ala627Val/c.1880C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1918,44,1978,"0,0222446916",0,0,0,0,1,1,0,1,3,NO,NO,COSM4097553,stomach,1,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,"0,015",Damaging,"31,8","27,41"
"low freq, bad alignment, many artifacts",UPN2_081,20,31022397,A,G,missense_variant(MODERATE|MISSENSE|Aga/Gga|p.Arg628Gly/c.1882A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),1935,26,1975,"0,013164557",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,07",Deleterious,"0,002",Damaging,"31,02","31,73"
"low bq, many samples",UPN2_001,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),826,27,859,"0,0314318976",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,23","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_014,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4920,101,5041,"0,0200357072",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,87","16,57"
"low bq, low freq, many artifacts, many samples",UPN2_015,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),6865,148,7036,"0,0210346788",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,92","16,43"
"low bq, many samples",UPN2_016,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),2699,73,2786,"0,0262024408",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,97","16,49"
"low bq, many samples",UPN2_017,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1718,71,1802,"0,0394006659",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,07","15,69"
"low bq, many samples",UPN2_018,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3175,72,3260,"0,0220858896",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,82","16,33"
"low bq, low freq, many artifacts, many samples",UPN2_019,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3882,87,3981,"0,0218538056",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,86","17,24"
"low bq, low freq, many artifacts, many samples",UPN2_020,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),2934,64,3004,"0,0213049268",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,89","15,94"
"low bq, low freq, many artifacts, many samples",UPN2_021,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3324,73,3417,"0,0213637694",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,9","16,01"
"low bq, low freq, many artifacts, many samples",UPN2_002,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1356,29,1389,"0,0208783297",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,31","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_022,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5239,105,5364,"0,0195749441",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,31,"16,91"
"low bq, low freq, many artifacts, many samples",UPN2_023,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5804,113,5947,"0,0190011771",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,97","15,65"
"low bq, many samples",UPN2_041,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),9180,224,9452,"0,0236986881",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,95","15,78"
"low bq, low freq, many artifacts, many samples",UPN2_024,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),2610,58,2679,"0,0216498694",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,04","17,38"
"low bq, low freq, many artifacts, many samples",UPN2_026,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5700,110,5827,"0,0188776386",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,01","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_027,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5976,98,6085,"0,0161051767",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,31,"15,31"
"low bq, many samples",UPN2_042,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5638,134,5783,"0,0231713643",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,15","16,98"
"low bq, many samples",UPN2_028,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4025,92,4123,"0,0223138491",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,1","16,45"
"low bq, many samples",UPN2_043,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3603,101,3714,"0,0271943996",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,86","16,83"
"low bq, many samples",UPN2_044,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),911,36,949,"0,0379346681",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,76","15,72"
"low bq, many samples",UPN2_029,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5309,123,5455,"0,022548121",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,13","17,62"
"low bq, low freq, many artifacts, many samples",UPN2_030,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5493,119,5635,"0,0211180124",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,08","17,08"
"low bq, many samples",UPN2_031,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3505,123,3642,"0,0337726524",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,45","15,93"
"low bq, low freq, many artifacts, many samples",UPN2_032,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1621,36,1663,"0,0216476248",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,74","16,72"
"low bq, many samples",UPN2_046,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),6193,158,6387,"0,0247377486",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,81","15,89"
"low bq, many samples",UPN2_033,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3759,90,3859,"0,0233221042",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,77","16,03"
"low bq, many samples",UPN2_034,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1644,51,1697,"0,0300530348",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,8","14,76"
"low bq, many samples",UPN2_047,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),8164,195,8393,"0,0232336471",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,9","15,34"
"low bq, many samples",UPN2_048,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),7244,179,7440,"0,0240591398",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,9","16,3"
"low bq, low freq, many artifacts, many samples",UPN2_035,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4331,95,4435,"0,0214205186",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,75","14,98"
"low bq, many samples",UPN2_036,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3979,134,4129,"0,0324533785",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,61","15,27"
"low bq, many samples",UPN2_049,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),2908,123,3039,"0,0404738401",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,61","15,76"
"low bq, many samples",UPN2_050,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4515,105,4636,"0,0226488352",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,92","17,01"
"low bq, low freq, many artifacts, many samples",UPN2_037,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),8003,145,8182,"0,0177218284",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,31,"16,47"
"low bq, many samples",UPN2_051,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4496,117,4634,"0,0252481657",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,06","17,5"
"low bq, many samples",UPN2_052,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3955,113,4092,"0,0276148583",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,21","16,78"
"low bq, low freq, many artifacts, many samples",UPN2_038,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),8783,188,9011,"0,0208633892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,94","15,78"
"low bq, many samples",UPN2_039,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4428,158,4601,"0,0343403608",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,58","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_053,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5876,132,6039,"0,0218579235",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,97","15,95"
"low bq, many samples",UPN2_054,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3220,76,3304,"0,0230024213",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,93","16,54"
"low bq, many samples",UPN2_007,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),2360,57,2427,"0,0234857849",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,24","15,51"
"low bq, many samples",UPN2_008,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4249,106,4361,"0,0243063518",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,4","14,93"
"low bq, many samples",UPN2_009,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3589,98,3696,"0,0265151515",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,28","15,22"
"low bq, many samples",UPN2_010,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1857,46,1908,"0,0241090147",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,23","15,02"
"low bq, many samples",UPN2_011,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1792,44,1839,"0,0239260468",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,98","15,8"
"low bq, low freq, many artifacts, many samples",UPN2_055,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5980,122,6121,"0,0199313838",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,19","16,9"
"low bq, low freq, many artifacts, many samples",UPN2_057,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4108,89,4210,"0,0211401425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,99","16,44"
"low bq, many samples",UPN2_058,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),8220,205,8453,"0,0242517449",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,87","16,25"
"low bq, many samples",UPN2_012,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1436,38,1477,"0,0257278267",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,09","16,61"
"low bq, many samples",UPN2_040,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4069,133,4220,"0,0315165877",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,48","15,49"
"low bq, many samples",UPN2_013,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),992,24,1017,"0,0235988201",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,51","17,29"
"low bq, low freq, many artifacts, many samples",UPN2_071,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1645,23,1675,"0,0137313433",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,96","15,91"
"low bq, low freq, many artifacts",UPN2_102,20,31022397,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg628*/c.1882A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),2247,24,2282,"0,0105170903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,41","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_014,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4932,76,5042,"0,0150733836",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"32,01","16,76"
"low bq, low freq, many artifacts, many samples",UPN2_015,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),6915,94,7037,"0,013357965",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"31,8","15,8"
"low bq, low freq, many artifacts, many samples",UPN2_016,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),2733,39,2786,"0,0139985642",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"31,94","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_018,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3196,57,3260,"0,0174846626",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"31,76","15,88"
"low bq, low freq, many artifacts, many samples",UPN2_019,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3902,63,3981,"0,0158251696",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"32,22","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_020,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),2950,41,3003,"0,0136530137",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"32,07","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_021,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3338,69,3417,"0,0201931519",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"32,07","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_023,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5818,100,5947,"0,0168152009",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"32,1","16,71"
"low bq, low freq, many artifacts, many samples",UPN2_041,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),9235,166,9449,"0,0175679966",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"31,62","15,54"
"low bq, low freq, many artifacts, many samples",UPN2_024,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),2620,48,2679,"0,0179171333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"32,26","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_026,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5705,91,5827,"0,0156169556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"31,97","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_027,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5958,96,6084,"0,0157790927",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"32,09","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_042,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5639,113,5783,"0,0195400311",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"31,66","15,83"
"low bq, low freq, many artifacts, many samples",UPN2_043,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3614,77,3714,"0,020732364",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"31,44","15,35"
"low bq, many samples",UPN2_044,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),915,26,949,"0,0273972603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"31,66","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_029,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5306,93,5455,"0,0170485793",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"32,17","16,48"
"low bq, low freq, many artifacts, many samples",UPN2_030,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5517,81,5635,"0,0143744454",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"32,21","15,73"
"low bq, low freq, many artifacts, many samples",UPN2_031,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3562,65,3643,"0,0178424376",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"31,39","16,03"
"low bq, low freq, many artifacts, many samples",UPN2_032,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1627,29,1662,"0,0174488568",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"31,77","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_046,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),6207,134,6388,"0,0209768316",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"31,68","15,65"
"low bq, low freq, many artifacts, many samples",UPN2_033,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3786,62,3859,"0,0160663384",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"31,87","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_034,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1653,37,1697,"0,0218031821",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"31,75","17,24"
"low bq, many samples",UPN2_047,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),8165,186,8395,"0,0221560453",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"31,5","16,82"
"low bq, low freq, many artifacts, many samples",UPN2_048,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),7244,135,7444,"0,0181354111",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"31,71","16,04"
"low bq, low freq, many artifacts, many samples",UPN2_035,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4336,81,4440,"0,0182432432",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"31,84","17,99"
"low bq, many samples",UPN2_049,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),2908,102,3036,"0,0335968379",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"31,14","16,5"
"low bq, low freq, many artifacts, many samples",UPN2_050,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4535,76,4637,"0,0163899073",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"31,73","15,49"
"low bq, low freq, many artifacts, many samples",UPN2_037,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),8031,115,8182,"0,0140552432",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"31,96","16,26"
"low bq, low freq, many artifacts, many samples",UPN2_051,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4517,99,4633,"0,0213684438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"31,89","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_052,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3994,78,4092,"0,0190615836",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"31,71","15,77"
"low bq, low freq, many artifacts, many samples",UPN2_038,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),8838,142,9009,"0,0157620158",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"31,93","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_053,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5892,115,6038,"0,0190460417",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"31,54","15,56"
"low bq, low freq, many artifacts, many samples",UPN2_054,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3211,68,3304,"0,0205811138",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"31,42","15,88"
"low bq, low freq, many artifacts, many samples",UPN2_007,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),2364,47,2427,"0,0193654718",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"31,58","15,96"
"low bq, low freq, many artifacts, many samples",UPN2_008,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4265,79,4362,"0,0181109583",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"31,48","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_009,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3614,70,3696,"0,0189393939",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"31,84","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_010,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1858,31,1908,"0,0162473795",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"31,92","15,71"
"low bq, low freq, many artifacts, many samples",UPN2_011,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1805,27,1838,"0,0146898803",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"31,29",14
"low bq, low freq, many artifacts, many samples",UPN2_055,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5965,113,6122,"0,0184580203",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"31,78","16,81"
"low bq, low freq, many artifacts, many samples",UPN2_057,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4115,72,4209,"0,017106201",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"31,5","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_058,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),8258,154,8454,"0,018216229",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"31,57","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_012,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1442,27,1477,"0,0182802979",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"31,77","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_071,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1630,24,1675,"0,0143283582",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"31,08",14
"low bq, low freq, many artifacts",UPN2_104,20,31022399,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg628Ser/c.1884A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3037,45,3090,"0,0145631068",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"31,9","14,49"
"Hotspot, Sanger other sample; leakage?",UPN2_018,20,31022402,TCACCACTGCCATAGAGAGGCGGC,T,frameshift_variant(HIGH||agagaggcggccaccactgccatc/|p.Glu635fs/c.1900_1922delAGAGAGGCGGCCACCACTGCCAT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T|INFO_REALIGN_3_PRIME),3207,40,3257,"0,0122812404",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"0,0001403",NO,NO,NA,NA,NA,NA,"32,76",NA
"low bq, many samples",UPN2_061,20,31022404,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His630Pro/c.1889A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),745,30,776,"0,0386597938",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,11,Damaging,"29,36",14
"low bq, many samples",UPN2_062,20,31022404,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His630Pro/c.1889A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),940,39,985,"0,0395939086",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,11,Damaging,"29,72","16,77"
"low bq, many samples",UPN2_063,20,31022404,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His630Pro/c.1889A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),596,21,619,"0,0339256866",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,11,Damaging,"30,12","15,67"
"low bq, many samples",UPN2_064,20,31022404,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His630Pro/c.1889A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),810,34,846,"0,0401891253",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,11,Damaging,"29,22","15,79"
"low bq, many samples",UPN2_065,20,31022404,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His630Pro/c.1889A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),810,26,839,"0,0309892729",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,11,Damaging,"29,57","15,35"
"low bq, many samples",UPN2_071,20,31022404,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His630Pro/c.1889A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1617,45,1672,"0,0269138756",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,11,Damaging,"29,33","16,36"
"low bq, many samples",UPN2_072,20,31022404,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His630Pro/c.1889A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1220,38,1261,"0,0301348136",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,11,Damaging,"29,23","15,68"
"low bq, many samples",UPN2_075,20,31022404,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His630Pro/c.1889A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1438,38,1487,"0,0255548083",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,11,Damaging,"29,64","18,74"
"low bq, many samples",UPN2_076,20,31022404,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His630Pro/c.1889A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),525,24,550,"0,0436363636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,11,Damaging,"28,51","16,21"
"low bq, many samples",UPN2_078,20,31022404,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His630Pro/c.1889A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1162,30,1200,"0,025",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,11,Damaging,"29,2",16
"low bq, low freq, many artifacts, many samples",UPN2_080,20,31022404,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His630Pro/c.1889A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1259,26,1291,"0,0201394268",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,11,Damaging,"29,21","15,62"
"low bq, many samples",UPN2_081,20,31022404,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His630Pro/c.1889A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1893,57,1971,"0,0289193303",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,11,Damaging,"29,73","14,93"
low bq,UPN2_083,20,31022404,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His630Pro/c.1889A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),615,20,637,"0,0313971743",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,11,Damaging,"28,95","14,35"
"inspected, many artifacts",UPN2_007,20,31022404,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His630Leu/c.1889A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),2358,47,2428,"0,0193574959",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,34",Neutral,"0,02",Damaging,"29,67","26,83"
"inspected, many artifacts",UPN2_048,20,31022404,AC,A,frameshift_variant(HIGH||cac/|p.His631fs/c.1891delC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),7328,82,7442,"0,0110185434",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,26",NA
"low bq, low freq, many artifacts",UPN2_071,20,31022407,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His631Pro/c.1892A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1648,20,1671,"0,0119688809",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,17,Damaging,"30,33","15,3"
"low bq, low freq, many artifacts",UPN2_041,20,31022407,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His631Leu/c.1892A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),9280,98,9441,"0,0103802563",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,83",Neutral,73,Tolerated,"30,9","20,33"
"low bq, low freq, many artifacts, many samples",UPN2_014,20,31022409,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys632Ser/c.1894T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),4871,52,4994,"0,010412495",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,5,Damaging,"28,26","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_015,20,31022409,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys632Ser/c.1894T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),6812,79,6984,"0,0113115693",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,5,Damaging,"28,01","15,72"
"low bq, low freq, many artifacts, many samples",UPN2_016,20,31022409,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys632Ser/c.1894T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),2721,32,2777,"0,0115232265",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,5,Damaging,"29,71","16,81"
"low bq, low freq, many artifacts, many samples",UPN2_021,20,31022409,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys632Ser/c.1894T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),3315,36,3398,"0,0105944673",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,5,Damaging,"28,18","15,42"
"low bq, low freq, many artifacts, many samples",UPN2_022,20,31022409,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys632Ser/c.1894T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),5159,70,5319,"0,0131603685",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,5,Damaging,"28,24","15,56"
"low bq, low freq, many artifacts, many samples",UPN2_023,20,31022409,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys632Ser/c.1894T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),5731,84,5911,"0,0142107934",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,5,Damaging,"28,11","15,83"
"low bq, low freq, many artifacts, many samples",UPN2_041,20,31022409,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys632Ser/c.1894T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),9149,129,9373,"0,0137629361",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,5,Damaging,"30,16","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_025,20,31022409,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys632Ser/c.1894T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),5598,65,5744,"0,011316156",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,5,Damaging,"27,68","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_026,20,31022409,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys632Ser/c.1894T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),5605,65,5763,"0,0112788478",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,5,Damaging,"28,09","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_027,20,31022409,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys632Ser/c.1894T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),5880,69,6038,"0,011427625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,5,Damaging,"27,95","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_042,20,31022409,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys632Ser/c.1894T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),5580,70,5704,"0,0122720898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,5,Damaging,"30,15","17,34"
"low bq, low freq, many artifacts, many samples",UPN2_043,20,31022409,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys632Ser/c.1894T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),3613,41,3689,"0,0111141231",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,5,Damaging,"30,36","16,17"
"low bq, low freq, many artifacts, many samples",UPN2_030,20,31022409,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys632Ser/c.1894T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),5432,67,5586,"0,0119942714",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,5,Damaging,"28,19","15,85"
"low bq, low freq, many artifacts, many samples",UPN2_031,20,31022409,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys632Ser/c.1894T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),3500,41,3594,"0,0114079021",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,5,Damaging,28,"17,2"
"low bq, low freq, many artifacts, many samples",UPN2_045,20,31022409,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys632Ser/c.1894T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),3956,44,4041,"0,010888394",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,5,Damaging,"30,05","15,25"
"low bq, low freq, many artifacts, many samples",UPN2_046,20,31022409,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys632Ser/c.1894T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),6171,69,6308,"0,0109384908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,5,Damaging,"30,07","16,39"
"low bq, low freq, many artifacts, many samples",UPN2_033,20,31022409,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys632Ser/c.1894T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),3690,54,3802,"0,014203051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,5,Damaging,"28,05","16,02"
"low bq, low freq, many artifacts, many samples",UPN2_034,20,31022409,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys632Ser/c.1894T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),1616,24,1677,"0,0143112701",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,5,Damaging,"27,68","16,71"
"low bq, low freq, many artifacts, many samples",UPN2_047,20,31022409,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys632Ser/c.1894T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),8132,106,8339,"0,0127113563",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,5,Damaging,"30,11","16,59"
"low bq, low freq, many artifacts, many samples",UPN2_048,20,31022409,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys632Ser/c.1894T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),7262,76,7413,"0,0102522595",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,5,Damaging,"30,14","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_035,20,31022409,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys632Ser/c.1894T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),4275,47,4387,"0,0107134716",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,5,Damaging,"28,09","15,66"
"low bq, low freq, many artifacts, many samples",UPN2_050,20,31022409,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys632Ser/c.1894T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),4506,58,4610,"0,0125813449",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,5,Damaging,"30,24","16,55"
"low bq, low freq, many artifacts, many samples",UPN2_037,20,31022409,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys632Ser/c.1894T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),7908,83,8110,"0,0102342787",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,5,Damaging,"28,15","15,76"
"low bq, low freq, many artifacts, many samples",UPN2_051,20,31022409,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys632Ser/c.1894T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),4484,50,4590,"0,0108932462",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,5,Damaging,"30,52","15,58"
"low bq, low freq, many artifacts, many samples",UPN2_052,20,31022409,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys632Ser/c.1894T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),3972,42,4048,"0,0103754941",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,5,Damaging,30,"16,83"
"low bq, low freq, many artifacts, many samples",UPN2_038,20,31022409,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys632Ser/c.1894T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),8680,112,8926,"0,0125476137",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,5,Damaging,"28,1","15,55"
"low bq, low freq, many artifacts, many samples",UPN2_039,20,31022409,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys632Ser/c.1894T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),4416,49,4532,"0,0108120035",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,5,Damaging,"27,61","15,37"
"low bq, low freq, many artifacts, many samples",UPN2_054,20,31022409,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys632Ser/c.1894T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),3206,37,3270,"0,0113149847",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,5,Damaging,"30,01","15,57"
"low bq, low freq, many artifacts, many samples",UPN2_007,20,31022409,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys632Ser/c.1894T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),2357,28,2409,"0,0116230801",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,5,Damaging,"29,68","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_009,20,31022409,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys632Ser/c.1894T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),3566,43,3643,"0,0118034587",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,5,Damaging,"29,74","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_010,20,31022409,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys632Ser/c.1894T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),1839,24,1879,"0,0127727515",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,5,Damaging,"29,57",14
"low bq, low freq, many artifacts, many samples",UPN2_011,20,31022409,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys632Ser/c.1894T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),1783,23,1828,"0,0125820569",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,5,Damaging,"29,54",14
"low bq, low freq, many artifacts, many samples",UPN2_057,20,31022409,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys632Ser/c.1894T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),4092,61,4182,"0,0145863223",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,5,Damaging,"30,16","15,82"
"low bq, low freq, many artifacts, many samples",UPN2_058,20,31022409,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys632Ser/c.1894T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),8152,97,8373,"0,0115848561",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,5,Damaging,"30,35","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_012,20,31022409,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys632Ser/c.1894T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),1425,21,1459,"0,0143934202",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,5,Damaging,"29,57","15,48"
"low bq, low freq, many artifacts",UPN2_040,20,31022409,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys632Ser/c.1894T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),4042,46,4160,"0,0110576923",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,5,Damaging,"27,82","18,65"
"low bq, low freq, many artifacts, many samples",UPN2_019,20,31022409,T,G,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys632Gly/c.1894T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3843,51,3945,"0,0129277567",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,5,Damaging,"28,12","16,18"
"low bq, low freq, many artifacts, many samples",UPN2_020,20,31022409,T,G,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys632Gly/c.1894T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),2876,41,2960,"0,0138513514",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,5,Damaging,"28,23","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_024,20,31022409,T,G,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys632Gly/c.1894T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),2582,40,2659,"0,0150432493",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,5,Damaging,"28,07","15,52"
"low bq, low freq, many artifacts, many samples",UPN2_028,20,31022409,T,G,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys632Gly/c.1894T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3968,63,4083,"0,015429831",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,5,Damaging,"27,94","15,59"
"low bq, low freq, many artifacts, many samples",UPN2_029,20,31022409,T,G,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys632Gly/c.1894T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),5283,62,5420,"0,0114391144",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,5,Damaging,"28,13","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_032,20,31022409,T,G,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys632Gly/c.1894T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),1600,32,1647,"0,0194292653",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,5,Damaging,"28,06","17,34"
"low bq, low freq, many artifacts, many samples",UPN2_036,20,31022409,T,G,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys632Gly/c.1894T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3959,58,4076,"0,0142296369",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,5,Damaging,"28,01","15,1"
"low bq, many samples",UPN2_062,20,31022409,T,G,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys632Gly/c.1894T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),938,24,972,"0,024691358",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,5,Damaging,"29,2","18,62"
"low bq, many samples",UPN2_063,20,31022409,T,G,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys632Gly/c.1894T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),579,20,607,"0,0329489292",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,5,Damaging,"29,68","18,4"
"low bq, many samples",UPN2_064,20,31022409,T,G,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys632Gly/c.1894T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),813,23,841,"0,0273483948",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,5,Damaging,"29,37","16,52"
"low bq, many samples",UPN2_065,20,31022409,T,G,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys632Gly/c.1894T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),806,21,836,"0,0251196172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,5,Damaging,"29,38","16,33"
"low bq, many samples",UPN2_071,20,31022409,T,G,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys632Gly/c.1894T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),1607,46,1670,"0,0275449102",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,5,Damaging,"29,14","15,54"
"low bq, many samples",UPN2_072,20,31022409,T,G,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys632Gly/c.1894T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),1184,34,1235,"0,0275303644",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,5,Damaging,"29,39","16,35"
"low bq, many samples",UPN2_075,20,31022409,T,G,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys632Gly/c.1894T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),1430,33,1478,"0,0223274696",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,5,Damaging,"29,25","14,39"
"low bq, many samples",UPN2_078,20,31022409,T,G,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys632Gly/c.1894T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),1148,32,1195,"0,0267782427",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,5,Damaging,"29,67","16,25"
"low bq, many samples",UPN2_080,20,31022409,T,G,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys632Gly/c.1894T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),1234,31,1280,"0,02421875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,5,Damaging,"29,26","15,55"
low bq,UPN2_081,20,31022409,T,G,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys632Gly/c.1894T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),1884,44,1939,"0,0226921093",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,5,Damaging,"29,13","17,32"
"low bq, low freq, many artifacts, many samples",UPN2_015,20,31022412,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His633Asn/c.1897C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),3439,36,3491,"0,0103122315",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,55",Neutral,273,Tolerated,"32,31","21,81"
"low bq, low freq, many artifacts, many samples",UPN2_016,20,31022412,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His633Asn/c.1897C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),1825,20,1863,"0,0107353731",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,55",Neutral,273,Tolerated,"31,66","19,4"
"low bq, low freq, many artifacts, many samples",UPN2_041,20,31022412,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His633Asn/c.1897C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),4462,47,4531,"0,0103729861",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,55",Neutral,273,Tolerated,"30,5","14,15"
"low bq, low freq, many artifacts, many samples",UPN2_042,20,31022412,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His633Asn/c.1897C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),2761,36,2809,"0,0128159487",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,55",Neutral,273,Tolerated,"30,77","17,36"
"low bq, many samples, no database",UPN2_043,20,31022412,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His633Asn/c.1897C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),1799,27,1843,"0,0146500271",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,55",Neutral,"0,273",Tolerated,"30,46","22,52"
"low bq, low freq, many artifacts, many samples",UPN2_031,20,31022412,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His633Asn/c.1897C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),1771,22,1797,"0,0122426266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,55",Neutral,273,Tolerated,"31,83","19,73"
"low bq, low freq, many artifacts, many samples",UPN2_045,20,31022412,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His633Asn/c.1897C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),1928,34,1979,"0,0171803941",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,55",Neutral,273,Tolerated,"29,39","16,65"
"low bq, low freq, many artifacts, many samples",UPN2_046,20,31022412,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His633Asn/c.1897C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),3075,65,3153,"0,020615287",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,55",Neutral,273,Tolerated,"30,48","21,31"
"low bq, many samples, no database",UPN2_047,20,31022412,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His633Asn/c.1897C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),4021,85,4138,"0,0205413243",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,55",Neutral,"0,273",Tolerated,"30,65","22,49"
"low bq, low freq, many artifacts, many samples",UPN2_050,20,31022412,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His633Asn/c.1897C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),2248,35,2296,"0,0152439024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,55",Neutral,273,Tolerated,"30,31","19,2"
"low bq, low freq, many artifacts, many samples",UPN2_051,20,31022412,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His633Asn/c.1897C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),2222,29,2275,"0,0127472527",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,55",Neutral,273,Tolerated,"30,83","19,97"
"low bq, low freq, many artifacts, many samples",UPN2_052,20,31022412,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His633Asn/c.1897C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),1988,25,2020,"0,0123762376",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,55",Neutral,273,Tolerated,"30,68","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_038,20,31022412,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His633Asn/c.1897C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),4400,53,4478,"0,0118356409",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,55",Neutral,273,Tolerated,"32,23","24,43"
"low bq, low freq, many artifacts, many samples",UPN2_053,20,31022412,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His633Asn/c.1897C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),2903,39,2967,"0,0131445905",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,55",Neutral,273,Tolerated,"30,54",20
"low bq, many samples, no database",UPN2_009,20,31022412,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His633Asn/c.1897C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),1807,26,1846,"0,014084507",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,55",Neutral,"0,273",Tolerated,"32,18","23,31"
"low bq, low freq, many artifacts, many samples",UPN2_055,20,31022412,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His633Asn/c.1897C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),2950,55,3026,"0,0181758096",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,55",Neutral,273,Tolerated,"30,7","20,04"
"low bq, low freq, many artifacts, many samples",UPN2_058,20,31022412,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His633Asn/c.1897C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),4083,51,4157,"0,0122684628",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,55",Neutral,273,Tolerated,"30,36","18,45"
"low bq, low freq, many artifacts, many samples",UPN2_040,20,31022412,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His633Asn/c.1897C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),2057,24,2088,"0,0114942529",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,55",Neutral,273,Tolerated,"31,74","22,25"
"low bq, many samples, no database",UPN2_107,20,31022412,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His633Asn/c.1897C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),2258,30,2300,"0,0130434783",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,55",Neutral,"0,273",Tolerated,"33,39","28,4"
"low bq, many samples, no database",UPN2_109,20,31022412,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His633Asn/c.1897C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),1821,22,1852,"0,0118790497",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,55",Neutral,"0,273",Tolerated,"33,36","27,09"
"low freq, many artifacts",UPN2_111,20,31022412,C,A,missense_variant(MODERATE|MISSENSE|Cat/Aat|p.His633Asn/c.1897C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),1343,21,1374,"0,0152838428",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,55",Neutral,273,Tolerated,"33,11","29,43"
"many artifacts, strandbias, many samples",UPN2_001,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),4100,885,5010,"0,1766467066",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,8","31,76"
"many artifacts, strandbias, many samples",UPN2_014,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),8894,1064,10022,"0,1061664338",0,1,0,0,1,1,0,0,3,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"32,05","31,62"
"many artifacts, strandbias, many samples",UPN2_015,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),11496,1115,12686,"0,0878921646",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"32,12","31,69"
"many artifacts, strandbias, many samples",UPN2_016,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),6047,649,6743,"0,0962479608",0,1,0,0,1,1,0,0,3,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,32,"31,57"
many samples,UPN2_017,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),2197,297,2507,"0,1184682888",0,0,0,0,0,1,0,0,1,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,29,Damaging,"31,75","31,56"
"many artifacts, strandbias, many samples",UPN2_018,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),5407,622,6072,"0,1024374177",0,1,0,0,0,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,99","31,7"
"many artifacts, strandbias, many samples",UPN2_019,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),6416,720,7183,"0,1002366699",0,1,0,0,1,1,0,0,3,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"32,08","31,66"
"many artifacts, strandbias, many samples",UPN2_020,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),5746,670,6450,"0,103875969",0,1,0,0,1,1,0,0,3,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"32,03","31,68"
"many artifacts, strandbias, many samples",UPN2_021,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),6405,805,7247,"0,1110804471",0,1,0,0,1,1,0,0,3,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,98","31,59"
"many artifacts, strandbias, many samples",UPN2_002,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),4411,1077,5503,"0,1957114301",0,1,0,0,1,1,0,0,3,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,88","31,61"
"many artifacts, strandbias, many samples",UPN2_003,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),810,202,1016,"0,1988188976",0,1,0,0,1,0,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,96","31,64"
"many artifacts, strandbias, many samples",UPN2_022,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9048,1085,10196,"0,1064142801",0,1,0,0,1,1,0,0,3,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"32,11","31,64"
"many artifacts, strandbias, many samples",UPN2_023,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9489,1103,10659,"0,1034806267",0,1,0,0,1,1,0,0,3,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"32,11","31,69"
"many artifacts, strandbias, many samples",UPN2_041,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),15270,712,16123,"0,044160516",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,67","31,4"
"many artifacts, strandbias, many samples",UPN2_024,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),4943,460,5445,"0,0844811754",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"32,09","31,58"
"many artifacts, strandbias, many samples",UPN2_025,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),11244,1455,12789,"0,1137696458",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,9","31,66"
"many artifacts, strandbias, many samples",UPN2_026,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9924,1164,11161,"0,1042917301",0,1,0,0,1,1,0,0,3,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"32,02","31,78"
"many artifacts, strandbias, many samples",UPN2_004,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),376,102,480,"0,2125",0,0,0,1,1,0,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"32,06","31,61"
"many artifacts, strandbias, many samples",UPN2_027,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9927,1309,11305,"0,1157894737",0,1,0,0,1,1,0,0,3,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"32,1","31,69"
"many artifacts, strandbias, many samples",UPN2_089,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),6896,310,7231,"0,0428709722",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"32,15","31,71"
"inspected, many artifacts, strandbias, many samples",UPN2_042,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),18087,1222,19406,"0,0629702154",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,73","31,56"
"many artifacts, strandbias, many samples",UPN2_028,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),6777,820,7658,"0,1070775659",0,1,0,0,1,1,0,0,3,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"32,12","31,63"
"inspected, many artifacts, strandbias, many samples",UPN2_043,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),12086,868,13025,"0,0666410749",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,73","31,51"
many samples,UPN2_044,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),2759,204,2972,"0,068640646",0,0,0,0,1,0,0,0,1,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,29,Damaging,"31,62","31,4"
"many artifacts, strandbias, many samples",UPN2_029,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9640,1183,10882,"0,1087116339",0,1,0,0,1,1,0,0,3,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"32,09","31,59"
"many artifacts, strandbias, many samples",UPN2_030,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9668,1109,10836,"0,1023440384",0,1,0,0,1,1,0,0,3,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"32,12","31,63"
"many artifacts, strandbias, many samples",UPN2_031,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),6397,678,7134,"0,0950378469",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,88","31,66"
"many artifacts, strandbias, many samples",UPN2_005,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),1453,343,1800,"0,1905555556",0,1,0,0,1,0,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,78","31,75"
"many artifacts, strandbias, many samples",UPN2_045,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),15789,789,16660,"0,0473589436",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,65","31,56"
"many artifacts, strandbias, many samples",UPN2_032,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3267,345,3632,"0,0949889868",0,1,0,0,1,1,0,0,3,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"32,02","31,8"
"many artifacts, strandbias, many samples",UPN2_046,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),13760,1124,15007,"0,0748983808",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,69","31,65"
"many artifacts, strandbias, many samples",UPN2_033,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),7406,854,8312,"0,1027430221",0,1,0,0,1,1,0,0,3,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,92","31,56"
"many artifacts, strandbias, many samples",UPN2_034,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),2831,279,3129,"0,0891658677",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"32,01","31,92"
"many artifacts, strandbias, many samples",UPN2_047,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),22555,1592,24295,"0,0655278864",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,72","31,62"
"many artifacts, strandbias, many samples",UPN2_048,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),17390,1294,18823,"0,0687456835",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,72","31,45"
"many artifacts, strandbias, many samples",UPN2_035,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),7979,947,8969,"0,105585907",0,1,0,0,1,1,0,0,3,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,32,"31,72"
"many artifacts, strandbias, many samples",UPN2_036,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),7427,860,8324,"0,1033157136",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,78","31,54"
"many artifacts, strandbias, many samples",UPN2_006,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),2486,563,3054,"0,1843483955",0,1,0,0,1,0,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,83","31,64"
many samples,UPN2_049,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),6376,449,6865,"0,0654042243",0,0,0,0,0,1,0,0,1,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,29,Damaging,"31,61","31,53"
"many artifacts, strandbias, many samples",UPN2_050,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),14864,642,15594,"0,0411696806",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,7","31,57"
"many artifacts, strandbias, many samples",UPN2_037,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),14044,1552,15695,"0,0988849952",0,1,0,0,1,1,0,0,3,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"32,1","31,68"
"many artifacts, strandbias, many samples",UPN2_051,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),12876,715,13672,"0,0522966647",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,78","31,53"
"many artifacts, strandbias, many samples",UPN2_052,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),11966,561,12583,"0,0445839625",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,73","31,56"
"many artifacts, strandbias, many samples",UPN2_038,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),15290,1833,17222,"0,1064336314",0,1,0,0,1,1,0,0,3,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"32,06","31,7"
"many artifacts, strandbias, many samples",UPN2_039,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),7232,802,8099,"0,0990245709",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,95","31,7"
"many artifacts, strandbias, many samples",UPN2_053,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),14546,1125,15773,"0,0713244151",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,77","31,5"
"many artifacts, strandbias, many samples",UPN2_054,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),8534,545,9133,"0,0596737107",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,71","31,54"
"many artifacts, strandbias, many samples",UPN2_007,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),11418,2383,13844,"0,1721323317",0,1,0,0,1,1,0,0,3,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,92","31,63"
"many artifacts, strandbias, many samples",UPN2_008,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),15436,3065,18581,"0,1649534471",0,1,0,0,1,1,0,0,3,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,86","31,66"
"many artifacts, strandbias, many samples",UPN2_009,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),12352,2280,14689,"0,1552181905",0,1,0,0,1,1,0,0,3,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,93","31,62"
"many artifacts, strandbias, many samples",UPN2_010,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),7154,1513,8702,"0,1738680763",0,1,0,0,1,1,0,0,3,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,91","31,69"
"many artifacts, strandbias, many samples",UPN2_011,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),8756,1897,10700,"0,1772897196",0,1,0,0,1,0,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,81","31,55"
"many artifacts, strandbias, many samples",UPN2_055,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),17457,1208,18787,"0,0642997818",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,74","31,4"
"many artifacts, strandbias, many samples",UPN2_056,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3360,216,3588,"0,0602006689",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,73","31,4"
"many artifacts, strandbias, many samples",UPN2_090,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),5916,237,6165,"0,0384428224",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"32,03","31,54"
"many artifacts, strandbias, many samples",UPN2_057,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),12281,1059,13414,"0,0789473684",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,67","31,49"
"many artifacts, strandbias, many samples",UPN2_058,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),13834,1160,15119,"0,0767246511",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,71","31,48"
"many artifacts, strandbias, many samples",UPN2_059,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),1501,244,1749,"0,1395082905",0,1,0,0,1,0,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,72","31,58"
"many artifacts, strandbias, many samples",UPN2_012,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),4655,899,5588,"0,1608804581",0,1,0,0,1,1,0,0,3,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,86","31,56"
"many artifacts, strandbias, many samples",UPN2_060,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),2973,496,3494,"0,1419576417",0,1,0,0,1,1,0,0,3,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,69","31,74"
"many artifacts, strandbias, many samples",UPN2_040,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),7106,736,7888,"0,093306288",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,96","31,62"
"many artifacts, strandbias, many samples",UPN2_013,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),2973,602,3588,"0,1677814939",0,1,0,0,1,0,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"32,01","31,8"
many samples,UPN2_091,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),5336,301,5646,"0,0533120793",0,0,0,0,1,0,0,0,1,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,29,Damaging,"32,04","31,63"
many samples,UPN2_092,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3396,151,3555,"0,0424753868",0,0,0,0,1,0,0,0,1,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,29,Damaging,"31,97","31,54"
"many artifacts, strandbias, many samples",UPN2_093,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),4225,187,4421,"0,0422981226",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"32,04","31,77"
"inspected, many artifacts, strandbias, many samples",UPN2_061,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),2195,337,2541,"0,1326249508",0,1,0,0,1,1,0,0,3,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,87","31,73"
"many artifacts, strandbias, many samples",UPN2_062,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3245,584,3841,"0,1520437386",0,1,0,0,1,0,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,87","31,7"
"many artifacts, strandbias, many samples",UPN2_063,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),2547,503,3054,"0,1647020301",0,1,0,0,1,1,0,0,3,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,91","31,79"
"many artifacts, strandbias, many samples",UPN2_064,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),1928,348,2286,"0,1522309711",0,1,0,0,1,1,0,0,3,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,92","31,65"
"many artifacts, strandbias, many samples",UPN2_065,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),1610,204,1822,"0,1119648738",0,1,0,0,1,0,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,84","31,74"
"many artifacts, strandbias, many samples",UPN2_066,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),683,123,807,"0,1524163569",0,1,0,0,1,0,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,64","31,85"
"many artifacts, strandbias, many samples",UPN2_067,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),834,149,984,"0,1514227642",0,1,0,0,1,0,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,72","31,78"
"many artifacts, strandbias, many samples",UPN2_068,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),1217,193,1412,"0,1366855524",0,1,0,0,1,0,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,82","31,51"
"many artifacts, strandbias, many samples",UPN2_069,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),2166,337,2514,"0,1340493238",0,1,0,0,1,1,0,0,3,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,73","31,45"
"many artifacts, strandbias, many samples",UPN2_070,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),1405,232,1644,"0,1411192214",0,1,0,0,1,1,0,0,3,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,79","31,36"
"many artifacts, strandbias, many samples",UPN2_071,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3926,627,4575,"0,1370491803",0,1,0,0,1,1,0,0,3,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,87","31,61"
"many artifacts, strandbias, many samples",UPN2_072,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3300,526,3842,"0,1369078605",0,1,0,0,1,1,0,0,3,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,91","31,7"
"many artifacts, strandbias, many samples",UPN2_073,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),2076,320,2408,"0,1328903654",0,1,0,0,1,0,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,79","31,71"
"many artifacts, strandbias, many samples",UPN2_074,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),900,150,1056,"0,1420454545",0,1,0,0,1,0,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,91","31,42"
"many artifacts, strandbias, many samples",UPN2_075,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),4570,740,5333,"0,1387586724",0,1,0,0,1,1,0,0,3,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,83","31,51"
"many artifacts, strandbias, many samples",UPN2_076,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),2178,360,2544,"0,141509434",0,1,0,0,1,1,0,0,3,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,83","31,59"
"many artifacts, strandbias, many samples",UPN2_077,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),2044,356,2405,"0,148024948",0,1,0,0,1,1,0,0,3,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,79","31,77"
"many artifacts, strandbias, many samples",UPN2_078,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),2972,419,3404,"0,1230904818",0,1,0,0,1,1,0,0,3,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,96","31,73"
"many artifacts, strandbias, many samples",UPN2_079,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),2082,302,2393,"0,1262014208",0,1,0,0,1,0,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,9","31,9"
"many artifacts, strandbias, many samples",UPN2_080,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3810,626,4449,"0,1407057766",0,1,0,0,1,1,0,0,3,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,86","31,49"
"many artifacts, strandbias, many samples",UPN2_081,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),4609,611,5239,"0,1166253102",0,1,0,0,1,1,0,0,3,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,32,"31,42"
"many artifacts, strandbias, many samples",UPN2_082,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),1735,246,1987,"0,1238047307",0,1,0,0,1,0,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,8","31,43"
"many artifacts, strandbias, many samples",UPN2_083,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),2517,442,2969,"0,148871674",0,1,0,0,1,1,0,0,3,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,75","31,62"
"many artifacts, strandbias, many samples",UPN2_084,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),2265,363,2635,"0,1377609108",0,1,0,0,1,1,0,0,3,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,78","31,57"
"many artifacts, strandbias, many samples",UPN2_085,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),921,149,1075,"0,1386046512",0,1,0,0,1,0,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"32,06",32
"many artifacts, strandbias, many samples",UPN2_086,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),706,111,823,"0,134872418",0,1,0,0,1,0,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,98","31,9"
"many artifacts, strandbias, many samples",UPN2_087,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),1973,319,2297,"0,1388767958",0,1,0,0,1,0,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,78","31,62"
"many artifacts, strandbias, many samples",UPN2_088,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),1816,315,2137,"0,1474029013",0,1,0,0,1,0,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"31,7","31,59"
"many artifacts, strandbias, many samples",UPN2_094,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),7832,338,8188,"0,0412799218",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"32,26","31,68"
"many artifacts, strandbias, many samples",UPN2_095,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),6184,325,6521,"0,0498389818",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"32,11","31,71"
"many artifacts, strandbias, many samples",UPN2_096,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),8020,335,8375,"0,04",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"32,11","31,76"
"many artifacts, strandbias, many samples",UPN2_097,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),8329,446,8786,"0,0507625768",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"32,13","31,69"
many samples,UPN2_098,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),6093,309,6405,"0,0482435597",0,0,0,0,1,0,0,0,1,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,29,Damaging,"31,98","31,69"
"many artifacts, strandbias, many samples",UPN2_099,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3882,177,4068,"0,0435103245",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"32,11","31,8"
"many artifacts, strandbias, many samples",UPN2_100,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),6976,266,7256,"0,0366593164",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"32,17","31,66"
"many artifacts, strandbias, many samples",UPN2_101,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),5702,221,5931,"0,0372618445",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"32,04","31,76"
"many artifacts, strandbias, many samples",UPN2_102,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),6212,276,6503,"0,0424419499",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"32,06","31,73"
many samples,UPN2_103,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),5673,253,5942,"0,0425782565",0,0,0,0,1,0,0,0,1,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,29,Damaging,"32,18","31,8"
many samples,UPN2_104,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),5615,254,5881,"0,0431899337",0,0,0,0,0,1,0,0,1,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,29,Damaging,"32,1","31,63"
"many artifacts, strandbias, many samples",UPN2_105,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),6417,309,6747,"0,0457981325",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"32,08","31,45"
"many artifacts, strandbias, many samples",UPN2_106,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),10625,382,11031,"0,03462968",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"32,23","31,8"
"many artifacts, strandbias, many samples",UPN2_107,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),12061,512,12596,"0,0406478247",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"32,09","31,68"
"inspected, strandbias",UPN2_108,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9267,339,9637,"0,0351769223",0,0,0,0,0,1,0,0,1,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,29,Damaging,"32,2","31,47"
"many artifacts, strandbias, many samples",UPN2_109,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),8726,282,9035,"0,0312119535",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"32,17","31,77"
"many artifacts, strandbias, many samples",UPN2_110,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9774,236,10037,"0,0235130019",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"32,15","31,45"
"many artifacts, strandbias, many samples",UPN2_111,20,31022413,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His633Arg/c.1898A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),7197,312,7523,"0,0414728167",0,0,0,0,1,1,0,0,2,"0,0118",0,NO,NA,NA,NO,rs201280462,NO,NO,NO,YES,"-0,79",Neutral,"0,029",Damaging,"32,06","31,73"
"inspected, many artifacts",UPN2_057,20,31022414,T,A,missense_variant(MODERATE|MISSENSE|caT/caA|p.His633Gln/c.1899T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),13122,189,13509,"0,0139906729",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,48",Neutral,"0,257",Tolerated,32,"30,12"
"low freq, many artifacts, many samples",UPN2_001,20,31022414,T,G,missense_variant(MODERATE|MISSENSE|caT/caG|p.His633Gln/c.1899T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),4947,61,5024,"0,0121417197",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,48",Neutral,257,Tolerated,"31,89",32
"inspected, many artifacts",UPN2_042,20,31022414,T,G,missense_variant(MODERATE|MISSENSE|caT/caG|p.His633Gln/c.1899T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),19096,207,19426,"0,0106558221",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,48",Neutral,"0,257",Tolerated,"31,98","31,37"
"low freq, many artifacts, many samples",UPN2_032,20,31022414,T,G,missense_variant(MODERATE|MISSENSE|caT/caG|p.His633Gln/c.1899T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3568,46,3640,"0,0126373626",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,48",Neutral,257,Tolerated,"32,38","31,76"
"low freq, many artifacts, many samples",UPN2_051,20,31022414,T,G,missense_variant(MODERATE|MISSENSE|caT/caG|p.His633Gln/c.1899T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),13434,165,13690,"0,0120525931",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,48",Neutral,257,Tolerated,"32,09","31,43"
many samples,UPN2_056,20,31022414,T,G,missense_variant(MODERATE|MISSENSE|caT/caG|p.His633Gln/c.1899T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3449,114,3589,"0,0317637225",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,48",Neutral,257,Tolerated,"31,99","31,84"
many samples,UPN2_059,20,31022414,T,G,missense_variant(MODERATE|MISSENSE|caT/caG|p.His633Gln/c.1899T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),1700,47,1750,"0,0268571429",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,48",Neutral,257,Tolerated,"31,9","31,62"
"low freq, many artifacts, many samples",UPN2_092,20,31022414,T,G,missense_variant(MODERATE|MISSENSE|caT/caG|p.His633Gln/c.1899T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3501,43,3554,"0,0120990433",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,48",Neutral,257,Tolerated,"32,11",32
"low freq, many artifacts, many samples",UPN2_063,20,31022414,T,G,missense_variant(MODERATE|MISSENSE|caT/caG|p.His633Gln/c.1899T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),2993,41,3059,"0,0134030729",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,48",Neutral,257,Tolerated,"31,97","31,12"
"low freq, many artifacts, many samples",UPN2_064,20,31022414,T,G,missense_variant(MODERATE|MISSENSE|caT/caG|p.His633Gln/c.1899T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),2250,28,2301,"0,0121686223",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,48",Neutral,257,Tolerated,"32,09",32
"low freq, many artifacts, many samples",UPN2_068,20,31022414,T,G,missense_variant(MODERATE|MISSENSE|caT/caG|p.His633Gln/c.1899T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),1381,29,1426,"0,0203366059",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,48",Neutral,257,Tolerated,"31,96","31,38"
"low freq, many artifacts, many samples",UPN2_073,20,31022414,T,G,missense_variant(MODERATE|MISSENSE|caT/caG|p.His633Gln/c.1899T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),2359,28,2421,"0,0115654688",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,48",Neutral,257,Tolerated,"31,89",32
"low freq, many artifacts, many samples",UPN2_075,20,31022414,T,G,missense_variant(MODERATE|MISSENSE|caT/caG|p.His633Gln/c.1899T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),5241,68,5335,"0,0127460169",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,48",Neutral,257,Tolerated,"32,01",32
"low freq, many artifacts, many samples",UPN2_079,20,31022414,T,G,missense_variant(MODERATE|MISSENSE|caT/caG|p.His633Gln/c.1899T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),2363,29,2396,"0,0121035058",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,48",Neutral,257,Tolerated,"31,99","31,38"
"low freq, many artifacts, many samples",UPN2_081,20,31022414,T,G,missense_variant(MODERATE|MISSENSE|caT/caG|p.His633Gln/c.1899T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),5190,53,5256,"0,0100837139",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,48",Neutral,257,Tolerated,"32,23",32
"low freq, many artifacts, many samples",UPN2_082,20,31022414,T,G,missense_variant(MODERATE|MISSENSE|caT/caG|p.His633Gln/c.1899T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),1955,21,1996,"0,0105210421",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,48",Neutral,257,Tolerated,"32,06",32
"low freq, many artifacts, many samples",UPN2_083,20,31022414,T,G,missense_variant(MODERATE|MISSENSE|caT/caG|p.His633Gln/c.1899T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),2917,45,2982,"0,0150905433",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,48",Neutral,257,Tolerated,"31,93",32
"low freq, many artifacts, many samples",UPN2_087,20,31022414,T,G,missense_variant(MODERATE|MISSENSE|caT/caG|p.His633Gln/c.1899T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),2257,26,2309,"0,0112602858",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,48",Neutral,257,Tolerated,"31,92","31,58"
"low freq, many artifacts",UPN2_095,20,31022414,T,G,missense_variant(MODERATE|MISSENSE|caT/caG|p.His633Gln/c.1899T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),6436,77,6540,"0,0117737003",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,48",Neutral,257,Tolerated,"32,32","31,77"
"low bq, low freq, many artifacts, many samples",UPN2_041,20,31022415,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg634*/c.1900A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15966,164,16196,"0,010125957",0,0,0,0,1,0,0,0,1,NO,NO,COSM1012900,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,81","16,8"
"low bq, low freq, many artifacts, many samples",UPN2_044,20,31022415,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg634*/c.1900A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),2925,34,2973,"0,0114362597",0,0,0,0,1,0,0,0,1,NO,NO,COSM1012900,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,95","22,85"
"low bq, low freq, many artifacts, many samples",UPN2_039,20,31022415,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg634*/c.1900A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),8028,96,8149,"0,0117805866",0,0,0,0,1,0,0,0,1,NO,NO,COSM1012900,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,77","16,26"
"low bq, low freq, many artifacts",UPN2_040,20,31022415,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg634*/c.1900A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),7795,81,7909,"0,010241497",0,0,0,0,1,0,0,0,1,NO,NO,COSM1012900,haematopoietic_and_lymphoid_tissue,2,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,73","16,7"
"low bq, low freq, many artifacts, many samples",UPN2_041,20,31022417,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg634Ser/c.1902A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15931,187,16204,"0,0115403604",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,2",Neutral,5,Damaging,31,"16,4"
"low bq, low freq, many artifacts, many samples",UPN2_025,20,31022417,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg634Ser/c.1902A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),12716,132,12917,"0,0102190911",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,2",Neutral,5,Damaging,"30,87","15,53"
"low bq, low freq, many artifacts, many samples",UPN2_036,20,31022417,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg634Ser/c.1902A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),8211,87,8407,"0,0103485191",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,2",Neutral,5,Damaging,"30,83","16,06"
"low bq, low freq, many artifacts, many samples",UPN2_039,20,31022417,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg634Ser/c.1902A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),8036,82,8168,"0,0100391773",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,2",Neutral,5,Damaging,"30,67","14,87"
"low bq, low freq, many artifacts",UPN2_058,20,31022417,A,T,missense_variant(MODERATE|MISSENSE|agA/agT|p.Arg634Ser/c.1902A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15001,194,15275,"0,012700491",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,2",Neutral,5,Damaging,"30,98","16,68"
"low bq, low freq, many artifacts, many samples",UPN2_025,20,31022419,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu635Val/c.1904A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),12678,133,12934,"0,0102829751",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,1,Damaging,"33,36","16,31"
"low bq, low freq, many artifacts, many samples",UPN2_031,20,31022419,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu635Val/c.1904A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),7074,79,7209,"0,0109585241",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,1,Damaging,"33,45","16,49"
"low bq, low freq, many artifacts, many samples",UPN2_036,20,31022419,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu635Val/c.1904A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),8216,111,8429,"0,0131688219",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,1,Damaging,"33,37","18,19"
"low bq, low freq, many artifacts, many samples",UPN2_039,20,31022419,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu635Val/c.1904A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),7998,106,8179,"0,0129600196",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,1,Damaging,"33,23","15,75"
"low bq, low freq, many artifacts, many samples",UPN2_058,20,31022419,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu635Val/c.1904A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15025,172,15289,"0,0112499182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,1,Damaging,"33,04","17,31"
"low bq, low freq, many artifacts",UPN2_040,20,31022419,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu635Val/c.1904A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),7759,93,7915,"0,0117498421",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,99",Neutral,1,Damaging,"33,13","14,88"
"low bq, low freq, many artifacts",UPN2_044,20,31022425,C,T,missense_variant(MODERATE|MISSENSE|gCc/gTc|p.Ala637Val/c.1910C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),2943,32,2983,"0,0107274556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,13",Deleterious,0,Damaging,"35,23","24,5"
"low bq, low freq, many artifacts, many samples",UPN2_049,20,31022436,A,T,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile641Phe/c.1921A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),7055,75,7157,"0,0104792511",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,98",Neutral,2,Damaging,"34,56","21,45"
"low freq, many artifacts, many samples",UPN2_056,20,31022436,A,T,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile641Phe/c.1921A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3578,38,3624,"0,0104856512",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,98",Neutral,2,Damaging,"35,07","30,79"
many samples,UPN2_001,20,31022441,A,+G,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|+G|INFO_REALIGN_3_PRIME),5021,1280,5082,"0,2518693428",0,0,1,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,97",NA
many samples,UPN2_025,20,31022441,A,+G,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|+G|INFO_REALIGN_3_PRIME),12618,3737,12944,"0,2887051916",0,0,1,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,05",NA
many samples,UPN2_045,20,31022441,A,+G,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|+G|INFO_REALIGN_3_PRIME),16513,3856,16813,"0,2293463391",0,0,1,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,77",NA
many samples,UPN2_036,20,31022441,A,+G,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|+G|INFO_REALIGN_3_PRIME),8226,1714,8443,"0,2030084093",0,0,1,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,05",NA
many samples,UPN2_039,20,31022441,A,+G,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|+G|INFO_REALIGN_3_PRIME),7957,1773,8195,"0,2163514338",0,0,1,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,84",NA
many samples,UPN2_040,20,31022441,A,+G,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|+G|INFO_REALIGN_3_PRIME),7712,1476,7927,"0,1861990665",0,0,1,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,95",NA
"ins and del, different ins, many samples",UPN2_083,20,31022441,A,+G,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|+G|INFO_REALIGN_3_PRIME),2987,732,3004,"0,2436750999",0,0,1,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,01",NA
"Hotspot, homopolymer 8G",UPN2_014,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),9958,434,10124,"0,0428684315",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,23",NA
"Hotspot, homopolymer 8G",UPN2_015,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),12555,461,12799,"0,0360184389",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,13",NA
"Hotspot, homopolymer 8G",UPN2_016,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),6695,265,6805,"0,0389419544",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,63",NA
"Hotspot, homopolymer 8G",UPN2_017,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),2630,91,2753,"0,0330548493",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,52",NA
"Hotspot, homopolymer 8G",UPN2_018,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),6044,402,6181,"0,0650380197",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,18",NA
"Hotspot, homopolymer 8G",UPN2_019,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),7118,362,7250,"0,0499310345",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,14",NA
"Hotspot, homopolymer 8G",UPN2_020,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),6423,238,6513,"0,0365423",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,42",NA
"Hotspot, homopolymer 8G",UPN2_021,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),7204,311,7323,"0,0424689335",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,3",NA
"Hotspot, homopolymer 8G",UPN2_002,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),5544,268,5593,"0,0479170392",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,74",NA
"Hotspot, homopolymer 8G",UPN2_003,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),1026,50,1034,"0,0483558994",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,98",NA
"Hotspot, homopolymer 8G",UPN2_022,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),10146,449,10309,"0,043554176",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,22",NA
"Hotspot, homopolymer 8G",UPN2_023,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),10576,428,10765,"0,0397584765",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,08",NA
"Hotspot, homopolymer 8G",UPN2_041,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),15879,618,16246,"0,038040133",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,99",NA
"Hotspot, homopolymer 8G",UPN2_024,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),5399,234,5478,"0,0427163198",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,34",NA
"Hotspot, homopolymer 8G",UPN2_026,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),11116,447,11299,"0,0395610231",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,14",NA
"Hotspot, homopolymer 8G",UPN2_027,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),11268,489,11436,"0,0427597062",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,19",NA
"Hotspot, homopolymer 8G",UPN2_089,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),7209,311,7273,"0,0427608965",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,01",NA
"Hotspot, homopolymer 8G",UPN2_042,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),19312,791,19572,"0,0404148784",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,7",NA
"Hotspot, homopolymer 8G",UPN2_028,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),7615,320,7735,"0,0413703943",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,16",NA
"Hotspot, homopolymer 8G",UPN2_043,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),12962,1088,13153,"0,0827187714",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,78",NA
"Hotspot, homopolymer 8G",UPN2_044,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),2929,113,2983,"0,0378813275",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,68",NA
"Hotspot, homopolymer 8G",UPN2_029,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),10810,481,10992,"0,0437590975",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,32",NA
"Hotspot, homopolymer 8G",UPN2_030,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),10737,424,10931,"0,0387887659",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,23",NA
"Hotspot, homopolymer 8G",UPN2_005,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),1796,76,1816,"0,0418502203",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,05",NA
"Hotspot, homopolymer 8G",UPN2_032,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),3636,154,3680,"0,0418478261",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,17",NA
"Hotspot, homopolymer 8G",UPN2_046,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),14862,567,15164,"0,0373911897",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,38",NA
"Hotspot, homopolymer 8G",UPN2_033,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),8237,391,8392,"0,0465919924",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,41",NA
"Hotspot, homopolymer 8G",UPN2_034,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),3101,105,3161,"0,0332173363",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,21",NA
"Hotspot, homopolymer 8G",UPN2_047,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),24143,910,24475,"0,0371807967",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,62",NA
"Hotspot, homopolymer 8G",UPN2_048,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),18690,712,18992,"0,0374894693",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,44",NA
"Hotspot, homopolymer 8G",UPN2_035,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),8915,745,9061,"0,0822205055",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,16",NA
many samples,UPN2_006,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),3055,149,3076,"0,0484395319",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,24",NA
"Hotspot, homopolymer 8G",UPN2_049,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),6955,303,7159,"0,042324347",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,14",NA
"Hotspot, homopolymer 8G",UPN2_050,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),15553,550,15768,"0,0348807712",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,63",NA
"Hotspot, homopolymer 8G",UPN2_037,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),15593,641,15832,"0,04048762",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,19",NA
"Hotspot, homopolymer 8G",UPN2_051,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),13558,508,13764,"0,0369078756",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,68",NA
"Hotspot, homopolymer 8G",UPN2_052,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),12547,452,12730,"0,0355066771",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,64",NA
"Hotspot, homopolymer 8G",UPN2_038,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),17093,666,17382,"0,0383154988",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,21",NA
"Hotspot, homopolymer 8G",UPN2_053,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),15673,576,15934,"0,0361491151",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,48",NA
"Hotspot, homopolymer 8G",UPN2_054,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),9006,345,9157,"0,0376760948",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,5",NA
"Hotspot, homopolymer 8G",UPN2_007,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),13856,610,13978,"0,0436400057",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,13",NA
"Hotspot, homopolymer 8G",UPN2_008,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),18609,787,18798,"0,041866156",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,92",NA
"Hotspot, homopolymer 8G",UPN2_009,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),14719,703,14871,"0,0472732163",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,88",NA
"Hotspot, homopolymer 8G",UPN2_010,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),8723,407,8812,"0,0461870177",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,02",NA
"Hotspot, homopolymer 8G",UPN2_011,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),10780,530,10853,"0,0488344237",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,01",NA
"Hotspot, homopolymer 8G",UPN2_055,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),18669,704,18924,"0,0372014373",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,7",NA
"Hotspot, homopolymer 8G",UPN2_056,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),3569,120,3623,"0,0331217223",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,75",NA
"Hotspot, homopolymer 8G",UPN2_090,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),6209,261,6245,"0,0417934347",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,19",NA
"Hotspot, homopolymer 8G",UPN2_057,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),13442,839,13616,"0,0616186839",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,61",NA
"Hotspot, homopolymer 8G",UPN2_058,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),14990,800,15306,"0,0522670848",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,99",NA
"Hotspot, homopolymer 8G",UPN2_059,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),1767,70,1772,"0,039503386",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,1",NA
"Hotspot, homopolymer 8G",UPN2_012,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),5593,369,5659,"0,0652058668",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,79",NA
"Hotspot, 2nd Illumina, homopolymer 8G",UPN2_013,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),3574,163,3620,"0,0450276243",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,78",NA
"Hotspot, homopolymer 8G",UPN2_091,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),5633,252,5675,"0,0444052863",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,2",NA
"Hotspot, homopolymer 8G",UPN2_092,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),3546,165,3572,"0,0461926092",0,0,0,1,0,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,28",NA
"Hotspot, homopolymer 8G",UPN2_093,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),4447,159,4476,"0,0355227882",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,17",NA
"Hotspot, homopolymer 8G",UPN2_061,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),2545,157,2564,"0,0612324493",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,86",NA
"Hotspot, homopolymer 8G",UPN2_062,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),3863,163,3886,"0,0419454452",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,04",NA
"Hotspot, homopolymer 8G",UPN2_063,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),3069,117,3083,"0,0379500487",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,23",NA
"Hotspot, homopolymer 8G",UPN2_064,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),2301,106,2311,"0,0458675898",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,81",NA
"Hotspot, homopolymer 8G",UPN2_065,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),1825,85,1838,"0,0462459195",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,56",NA
"Hotspot, homopolymer 8G",UPN2_066,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),812,42,813,"0,0516605166",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,01",NA
"Hotspot, homopolymer 8G",UPN2_067,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),1003,50,1005,"0,0497512438",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,23",NA
"Hotspot, homopolymer 8G",UPN2_068,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),1442,58,1449,"0,0400276052",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,19",NA
"Hotspot, homopolymer 8G",UPN2_069,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),2514,126,2531,"0,0497826946",0,0,0,1,0,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,13",NA
"Hotspot, homopolymer 8G",UPN2_070,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),1646,81,1660,"0,0487951807",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,14",NA
"Hotspot, homopolymer 8G",UPN2_071,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),4610,292,4644,"0,0628768303",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,75",NA
"Hotspot, homopolymer 8G",UPN2_072,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),3851,175,3876,"0,0451496388",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,87",NA
"Hotspot, homopolymer 8G",UPN2_073,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),2418,98,2440,"0,0401639344",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,21",NA
"Hotspot, homopolymer 8G",UPN2_074,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),1056,45,1063,"0,0423330198",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,17",NA
"Hotspot, homopolymer 8G",UPN2_075,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),5350,219,5377,"0,0407290311",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,96",NA
"Hotspot, homopolymer 8G",UPN2_076,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),2572,96,2584,"0,0371517028",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,09",NA
"ins and del, different ins, many samples",UPN2_077,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),2403,103,2419,"0,0425795783",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,21",NA
"Hotspot, homopolymer 8G",UPN2_078,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),3390,123,3419,"0,0359754314",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,8",NA
"Hotspot, homopolymer 8G",UPN2_079,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),2407,99,2419,"0,0409260025",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,04",NA
"Hotspot, homopolymer 8G",UPN2_080,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),4477,175,4496,"0,0389234875",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,97",NA
"Hotspot, homopolymer 8G",UPN2_081,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),5268,250,5304,"0,0471342383",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,83",NA
"Hotspot, homopolymer 8G",UPN2_082,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),1992,88,2009,"0,043802887",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,88",NA
"Hotspot, homopolymer 8G",UPN2_084,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),2661,130,2679,"0,0485255692",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,1",NA
"Hotspot, homopolymer 8G",UPN2_085,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),1093,44,1103,"0,0398912058",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,53",NA
"Hotspot, 2nd Illumina, homopolymer 8G",UPN2_086,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),828,40,834,"0,0479616307",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,09",NA
"Hotspot, homopolymer 8G",UPN2_087,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),2303,104,2323,"0,0447696944",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,98",NA
"Hotspot, homopolymer 8G",UPN2_088,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),2137,88,2149,"0,0409492787",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,1",NA
"Hotspot, homopolymer 8G",UPN2_094,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),8183,352,8236,"0,0427391938",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,93",NA
"Hotspot, homopolymer 8G",UPN2_095,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),6512,252,6556,"0,038438072",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,96",NA
"Hotspot, homopolymer 8G",UPN2_096,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),8353,370,8419,"0,0439482124",1,0,0,1,0,1,0,1,4,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,03",NA
"Hotspot, homopolymer 8G",UPN2_097,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),8781,390,8847,"0,0440827399",1,0,0,1,0,1,0,1,4,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,03",NA
"Hotspot, homopolymer 8G",UPN2_099,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),4069,184,4091,"0,0449767783",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,07",NA
"Hotspot, homopolymer 8G",UPN2_100,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),7259,270,7309,"0,036940758",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,14",NA
"Hotspot, homopolymer 8G",UPN2_101,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),5949,234,5984,"0,0391042781",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,12",NA
"Hotspot, homopolymer 8G",UPN2_102,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),6481,261,6536,"0,0399326805",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,92",NA
"Hotspot, homopolymer 8G",UPN2_103,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),5955,272,5985,"0,0454469507",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,95",NA
"Hotspot, homopolymer 8G",UPN2_104,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),6126,254,6246,"0,0406660263",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,45",NA
"Hotspot, homopolymer 8G",UPN2_105,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),6760,285,6808,"0,0418625147",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,94",NA
"Hotspot, homopolymer 8G",UPN2_106,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),11045,487,11112,"0,0438264939",1,0,0,1,0,1,0,1,4,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,07",NA
"Hotspot, homopolymer 8G",UPN2_107,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),12548,501,12641,"0,0396329404",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,02",NA
"Hotspot, homopolymer 8G",UPN2_108,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),9770,405,9879,"0,0409960522",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,89",NA
"Hotspot, homopolymer 8G",UPN2_109,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),9019,424,9082,"0,046685752",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,35,NA
"Hotspot, homopolymer 8G",UPN2_110,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),10038,378,10103,"0,0374146293",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,03",NA
"Hotspot, homopolymer 8G",UPN2_111,20,31022441,A,AG,frameshift_variant(HIGH||ggt/ggGt|p.Gly646fs/c.1934dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AG|INFO_REALIGN_3_PRIME),7539,324,7589,"0,042693372",0,0,0,1,0,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,07",NA
many samples,UPN2_025,20,31022441,A,AGG,frameshift_variant(HIGH||ggt/ggGGt|p.Gly646fs/c.1933_1934dupGG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AGG|INFO_REALIGN_3_PRIME),12618,333,12944,"0,0257262052",0,0,0,0,0,0,0,1,1,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,05",NA
"low freq, many artifacts, many samples",UPN2_031,20,31022441,A,AGG,frameshift_variant(HIGH||ggt/ggGGt|p.Gly646fs/c.1933_1934dupGG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AGG|INFO_REALIGN_3_PRIME),7067,101,7228,"0,0139734366",0,0,0,0,0,0,0,1,1,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,02",NA
many samples,UPN2_036,20,31022441,A,AGG,frameshift_variant(HIGH||ggt/ggGGt|p.Gly646fs/c.1933_1934dupGG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AGG|INFO_REALIGN_3_PRIME),8226,313,8443,"0,0370721308",0,0,0,0,0,0,0,1,1,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,05",NA
many samples,UPN2_039,20,31022441,A,AGG,frameshift_variant(HIGH||ggt/ggGGt|p.Gly646fs/c.1933_1934dupGG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AGG|INFO_REALIGN_3_PRIME),7957,365,8195,"0,0445393533",0,0,0,0,0,0,0,1,1,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,84",NA
"low freq, many artifacts, many samples",UPN2_060,20,31022441,A,AGG,frameshift_variant(HIGH||ggt/ggGGt|p.Gly646fs/c.1933_1934dupGG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AGG|INFO_REALIGN_3_PRIME),3518,46,3543,"0,0129833474",0,0,0,0,0,0,0,1,1,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,91",NA
"ins and del, different ins, many samples",UPN2_040,20,31022441,A,AGG,frameshift_variant(HIGH||ggt/ggGGt|p.Gly646fs/c.1933_1934dupGG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AGG|INFO_REALIGN_3_PRIME),7712,189,7927,"0,0238425634",0,0,0,0,0,0,0,1,1,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,95",NA
"Homopolymer 8G, ins and del, many samples",UPN2_001,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),4915,159,5090,"0,031237721",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,37",NA
"Homopolymer 8G, ins and del, many samples",UPN2_014,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),9688,400,10140,"0,0394477318",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,37",NA
"Homopolymer 8G, ins and del, many samples",UPN2_015,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),12268,477,12812,"0,0372307212",0,0,0,1,0,1,0,1,3,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,37",NA
"Homopolymer 8G, ins and del, many samples",UPN2_016,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),6498,286,6815,"0,0419662509",0,0,0,1,0,1,0,1,3,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,38",NA
"Homopolymer 8G, ins and del, many samples",UPN2_017,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),2661,94,2767,"0,0339718106",0,0,0,1,0,1,0,1,3,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,48",NA
"Homopolymer 8G, ins and del, many samples",UPN2_018,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),5923,242,6195,"0,0390637611",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,4",NA
"Homopolymer 8G, ins and del, many samples",UPN2_019,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),6863,347,7260,"0,0477961433",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,36",NA
"Homopolymer 8G, ins and del, many samples",UPN2_020,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),6192,285,6517,"0,0437317784",0,0,0,1,0,1,0,1,3,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,38",NA
"Homopolymer 8G, ins and del, many samples",UPN2_021,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),6994,293,7331,"0,0399672623",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,34",NA
"Homopolymer 8G, ins and del, many samples",UPN2_002,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),5350,211,5596,"0,0377055039",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,38",NA
"Homopolymer 8G, ins and del, many samples",UPN2_003,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),1006,24,1034,"0,0232108317",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,43",NA
"Homopolymer 8G, ins and del, many samples",UPN2_022,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),9818,463,10324,"0,0448469585",0,0,0,1,0,1,0,1,3,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,36",NA
"Homopolymer 8G, ins and del, many samples",UPN2_023,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),10271,455,10779,"0,042211708",0,0,0,1,0,1,0,1,3,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,35",NA
"Homopolymer 8G, ins and del, many samples",UPN2_041,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),15475,645,16272,"0,0396386431",0,0,0,1,0,1,0,1,3,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,02",NA
"Homopolymer 8G, ins and del, many samples",UPN2_024,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),5259,194,5483,"0,0353820901",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,37",NA
"Homopolymer 8G, ins and del, many samples",UPN2_025,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),12575,357,12981,"0,0275017333",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,33",NA
"Homopolymer 8G, ins and del, many samples",UPN2_026,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),10786,469,11318,"0,0414384167",0,0,0,1,0,1,0,1,3,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,4",NA
"ins and del, different ins, many samples",UPN2_004,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),469,20,493,"0,0405679513",0,0,0,1,0,0,0,0,1,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,57",NA
"Homopolymer 8G, ins and del, many samples",UPN2_027,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),10941,451,11454,"0,0393748909",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,41",NA
"Homopolymer 8G, ins and del, many samples",UPN2_089,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),7014,241,7278,"0,0331134927",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,23",NA
"Homopolymer 8G, ins and del, many samples",UPN2_042,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),18716,769,19596,"0,0392427026",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,03",NA
"Homopolymer 8G, ins and del, many samples",UPN2_028,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),7403,310,7745,"0,0400258231",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,4",NA
"Homopolymer 8G, ins and del, many samples",UPN2_043,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),12599,496,13169,"0,0376642114",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,06",NA
"Homopolymer 8G, ins and del, many samples",UPN2_044,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),2848,115,2985,"0,0385259631",0,0,0,1,0,1,0,1,3,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,08",NA
"Homopolymer 8G, ins and del, many samples",UPN2_029,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),10471,475,11003,"0,0431700445",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,38",NA
"Homopolymer 8G, ins and del, many samples",UPN2_030,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),10397,489,10942,"0,0446901846",0,0,0,1,0,1,0,1,3,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,4",NA
"Homopolymer 8G, ins and del, many samples",UPN2_031,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),6960,258,7241,"0,0356304378",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,37",NA
"Homopolymer 8G, ins and del, many samples",UPN2_005,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),1743,66,1818,"0,0363036304",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,43",NA
"Homopolymer 8G, ins and del, many samples",UPN2_045,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),16182,546,16850,"0,0324035608",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,99",NA
"Homopolymer 8G, ins and del, many samples",UPN2_032,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),3513,147,3682,"0,0399239544",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,42",NA
"Homopolymer 8G, ins and del, many samples",UPN2_046,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),14471,634,15190,"0,0417379855",0,0,0,1,0,1,0,1,3,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,03",NA
"Homopolymer 8G, ins and del, many samples",UPN2_033,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),8032,332,8406,"0,0394955984",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,39",NA
"Homopolymer 8G, ins and del, many samples",UPN2_034,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),3039,114,3167,"0,0359962109",0,0,0,1,0,1,0,1,3,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,39",NA
"Homopolymer 8G, ins and del, many samples",UPN2_047,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),23358,995,24515,"0,0405873955",0,0,0,1,0,1,0,1,3,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,02",NA
"Homopolymer 8G, ins and del, many samples",UPN2_048,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),18054,842,19023,"0,0442622089",0,0,0,1,0,1,0,1,3,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,08",NA
"Homopolymer 8G, ins and del, many samples",UPN2_035,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),8717,329,9074,"0,0362574388",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,39",NA
"Homopolymer 8G, ins and del, many samples",UPN2_036,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),8147,288,8471,"0,0339983473",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,38",NA
"Homopolymer 8G, ins and del, many samples",UPN2_006,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),2880,183,3079,"0,0594348815",0,0,0,1,0,1,0,0,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,35",NA
"Homopolymer 8G, ins and del, many samples",UPN2_049,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),6859,280,7186,"0,0389646535",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,04",NA
"Homopolymer 8G, ins and del, many samples",UPN2_050,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),15093,602,15785,"0,0381374723",0,0,0,1,0,1,0,1,3,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,07",NA
"Homopolymer 8G, ins and del, many samples",UPN2_037,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),15147,615,15849,"0,03880371",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,38",NA
"Homopolymer 8G, ins and del, many samples",UPN2_051,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),13127,553,13782,"0,0401248005",0,0,0,1,0,1,0,1,3,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,97",NA
"Homopolymer 8G, ins and del, many samples",UPN2_052,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),12188,484,12748,"0,0379667399",0,0,0,1,0,1,0,1,3,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,01",NA
"Homopolymer 8G, ins and del, many samples",UPN2_038,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),16585,725,17403,"0,041659484",0,0,0,1,0,1,0,1,3,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,37",NA
"Homopolymer 8G, ins and del, many samples",UPN2_039,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),7902,282,8218,"0,0343149185",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,38",NA
"Homopolymer 8G, ins and del, many samples",UPN2_053,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),15220,621,15950,"0,0389341693",0,0,0,1,0,1,0,1,3,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,02",NA
"Homopolymer 8G, ins and del, many samples",UPN2_054,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),8730,379,9181,"0,0412809062",0,0,0,1,0,1,0,1,3,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,05",NA
"Homopolymer 8G, ins and del, many samples",UPN2_007,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),13354,572,13985,"0,0409009653",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,36",NA
"Homopolymer 8G, ins and del, many samples",UPN2_008,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),17973,765,18817,"0,0406547271",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,38",NA
"Homopolymer 8G, ins and del, many samples",UPN2_009,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),14239,560,14879,"0,037636938",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,36",NA
"Homopolymer 8G, ins and del, many samples",UPN2_010,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),8354,414,8816,"0,0469600726",0,0,0,1,0,1,0,1,3,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,38",NA
"Homopolymer 8G, ins and del, many samples",UPN2_011,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),10328,476,10859,"0,0438346072",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,32",NA
"Homopolymer 8G, ins and del, many samples",UPN2_055,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),18006,816,18951,"0,0430584138",0,0,0,1,0,1,0,1,3,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,35,NA
"Homopolymer 8G, ins and del, many samples",UPN2_056,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),3464,126,3627,"0,0347394541",0,0,0,1,0,1,0,1,3,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,99",NA
"Homopolymer 8G, ins and del, many samples",UPN2_090,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),5966,252,6252,"0,0403071017",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,28",NA
"Homopolymer 8G, ins and del, many samples",UPN2_057,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),13026,511,13637,"0,0374715847",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,97",NA
"Homopolymer 8G, ins and del, many samples",UPN2_058,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),14594,640,15336,"0,0417318727",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,97",NA
"Homopolymer 8G, ins and del, many samples",UPN2_059,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),1703,63,1773,"0,0355329949",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,02",NA
"Homopolymer 8G, ins and del, many samples",UPN2_012,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),5380,251,5664,"0,0443149718",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,36",NA
"Homopolymer 8G, ins and del, many samples",UPN2_060,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),3400,136,3552,"0,0382882883",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,09",NA
"Homopolymer 8G, ins and del, many samples",UPN2_040,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),7710,220,7961,"0,0276347193",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,31",NA
"Homopolymer 8G, ins and del, many samples",UPN2_013,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),3458,140,3621,"0,0386633527",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,39",NA
"Homopolymer 8G, ins and del, many samples",UPN2_091,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),5435,215,5681,"0,0378454497",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,23",NA
"Homopolymer 8G, ins and del, many samples",UPN2_092,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),3403,161,3573,"0,0450601735",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,32",NA
"Homopolymer 8G, ins and del, many samples",UPN2_093,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),4254,197,4478,"0,043992854",0,0,0,1,0,1,0,1,3,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,21",NA
"Homopolymer 8G, ins and del, many samples",UPN2_061,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),2431,112,2564,"0,0436817473",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,17",NA
"Homopolymer 8G, ins and del, many samples",UPN2_062,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),3729,140,3889,"0,0359989715",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,05",NA
"Homopolymer 8G, ins and del, many samples",UPN2_063,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),2948,127,3089,"0,041113629",0,0,0,1,0,1,0,1,3,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,18",NA
"Homopolymer 8G, ins and del, many samples",UPN2_064,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),2241,65,2314,"0,0280898876",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,94",NA
"Homopolymer 8G, ins and del, many samples",UPN2_065,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),1758,73,1840,"0,039673913",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,7",NA
"Homopolymer 8G, ins and del, many samples",UPN2_066,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),777,23,813,"0,0282902829",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,96",NA
"Homopolymer 8G, ins and del, many samples",UPN2_067,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),971,28,1005,"0,0278606965",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,35,NA
"Homopolymer 8G, ins and del, many samples",UPN2_068,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),1376,68,1450,"0,0468965517",0,0,0,1,0,1,0,1,3,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,17",NA
"Homopolymer 8G, ins and del, many samples",UPN2_069,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),2417,105,2533,"0,0414528227",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,35,NA
"Homopolymer 8G, ins and del, many samples",UPN2_070,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),1590,63,1660,"0,0379518072",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,24",NA
"Homopolymer 8G, ins and del, many samples",UPN2_071,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),4444,184,4648,"0,0395869191",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,93",NA
"Homopolymer 8G, ins and del, many samples",UPN2_072,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),3728,136,3881,"0,0350425148",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,08",NA
"Homopolymer 8G, ins and del, many samples",UPN2_073,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),2320,105,2440,"0,0430327869",0,0,0,1,0,1,0,1,3,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,02",NA
"Homopolymer 8G, ins and del, many samples",UPN2_074,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),997,60,1065,"0,0563380282",0,0,0,1,0,1,0,1,3,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,1",NA
"Homopolymer 8G, ins and del, many samples",UPN2_075,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),5127,232,5377,"0,0431467361",0,0,0,1,0,1,0,1,3,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,04",NA
"Homopolymer 8G, ins and del, many samples",UPN2_076,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),2483,86,2586,"0,0332559938",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,2",NA
"Homopolymer 8G, ins and del, many samples",UPN2_077,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),2313,103,2420,"0,0425619835",0,0,0,1,0,1,0,1,3,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,17",NA
"Homopolymer 8G, ins and del, many samples",UPN2_078,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),3249,156,3421,"0,0456007015",0,0,0,1,0,1,0,1,3,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,04",NA
"Homopolymer 8G, ins and del, many samples",UPN2_079,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),2326,81,2419,"0,0334849111",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,04",NA
"Homopolymer 8G, ins and del, many samples",UPN2_080,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),4281,194,4501,"0,043101533",0,0,0,1,0,1,0,1,3,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,98",NA
"Homopolymer 8G, ins and del, many samples",UPN2_081,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),5035,251,5310,"0,0472693032",0,0,0,1,0,1,0,1,3,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,89",NA
"Homopolymer 8G, ins and del, many samples",UPN2_082,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),1894,109,2009,"0,0542558487",0,0,0,1,0,1,0,1,3,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,93",NA
"Homopolymer 8G, ins and del, many samples",UPN2_083,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),2904,90,3011,"0,0298904019",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,13",NA
"Homopolymer 8G, ins and del, many samples",UPN2_084,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),2561,102,2681,"0,0380455054",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,94",NA
"Homopolymer 8G, ins and del, many samples",UPN2_085,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),1073,29,1104,"0,0262681159",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,9",NA
"Homopolymer 8G, ins and del, many samples",UPN2_086,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),796,33,834,"0,0395683453",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,77",NA
"Homopolymer 8G, ins and del, many samples",UPN2_087,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),2237,76,2326,"0,0326741187",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,88",NA
"Homopolymer 8G, ins and del, many samples",UPN2_088,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),2030,97,2151,"0,0450953045",0,0,0,1,0,1,0,1,3,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,04",NA
"Homopolymer 8G, ins and del, many samples",UPN2_094,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),7892,320,8242,"0,0388255278",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,29",NA
"Homopolymer 8G, ins and del, many samples",UPN2_095,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),6283,251,6561,"0,0382563634",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,29",NA
"Homopolymer 8G, ins and del, many samples",UPN2_096,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),8054,341,8426,"0,0404699739",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,27",NA
"Homopolymer 8G, ins and del, many samples",UPN2_097,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),8489,318,8853,"0,0359200271",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,22",NA
"Homopolymer 8G, ins and del, many samples",UPN2_098,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),6204,257,6491,"0,039593283",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,21",NA
"Homopolymer 8G, ins and del, many samples",UPN2_099,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),3907,160,4093,"0,0390911312",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,31",NA
"Homopolymer 8G, ins and del, many samples",UPN2_100,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),7016,266,7314,"0,0363686081",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,29",NA
"Homopolymer 8G, ins and del, many samples",UPN2_101,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),5754,216,5985,"0,0360902256",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,31",NA
"Homopolymer 8G, ins and del, many samples",UPN2_102,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),6267,239,6541,"0,0365387555",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,14",NA
"Homopolymer 8G, ins and del, many samples",UPN2_103,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),5741,236,6000,"0,0393333333",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,25",NA
"Homopolymer 8G, ins and del, many samples",UPN2_104,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),5985,252,6265,"0,0402234637",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,29",NA
"Homopolymer 8G, ins and del, many samples",UPN2_105,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),6520,264,6812,"0,038755138",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,2",NA
"Homopolymer 8G, ins and del, many samples",UPN2_106,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),10598,474,11118,"0,0426335672",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,25",NA
"Homopolymer 8G, ins and del, many samples",UPN2_107,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),12126,457,12654,"0,0361150624",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,25",NA
"Homopolymer 8G, ins and del, many samples",UPN2_108,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),9482,386,9898,"0,0389977773",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,28",NA
"Homopolymer 8G, ins and del, many samples",UPN2_109,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),8718,337,9091,"0,0370696293",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,2",NA
"Homopolymer 8G, ins and del, many samples",UPN2_110,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),9664,393,10116,"0,0388493476",0,0,0,1,0,1,0,1,3,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,26",NA
"Homopolymer 8G, ins and del, many samples",UPN2_111,20,31022441,AG,A,frameshift_variant(HIGH||ggt/|p.Gly645fs/c.1934delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),7296,275,7598,"0,0361937352",0,0,0,1,0,0,0,1,2,"4,4879",NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,27",NA
"low bq, low freq, many artifacts",UPN2_017,20,31022455,C,G,missense_variant(MODERATE|MISSENSE|cCg/cGg|p.Pro647Arg/c.1940C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),2737,30,2773,"0,010818608",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,87",Deleterious,0,Damaging,"33,91","14,73"
"low freq, many artifacts",UPN2_064,20,31022460,G,A,missense_variant(MODERATE|MISSENSE|Gga/Aga|p.Gly649Arg/c.1945G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),2283,24,2313,"0,0103761349",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,2,Damaging,"34,77",36
"low freq, many artifacts",UPN2_056,20,31022466,G,A,missense_variant(MODERATE|MISSENSE|Ggc/Agc|p.Gly651Ser/c.1951G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),3557,53,3622,"0,0146327996",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,09",Neutral,0,Damaging,"34,69","34,45"
"inspected, strandbias, bad alignment, ins and del",UPN2_045,20,31022471,C,CG,frameshift_variant(HIGH||gcc/gGcc|p.Ala654fs/c.1960dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|CG|INFO_REALIGN_3_PRIME),16657,1864,16780,"0,1110846246",0,0,0,1,0,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,92",NA
"low freq, many artifacts",UPN2_064,20,31022471,CG,C,frameshift_variant(HIGH||gcc/|p.Ala654fs/c.1960delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C|INFO_REALIGN_3_PRIME),2283,25,2311,"0,0108178278",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,68",NA
"low bq, low freq, many artifacts, many samples",UPN2_045,20,31022478,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr655Pro/c.1963A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16476,178,16749,"0,0106275001",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,81",Neutral,15,Damaging,"29,9","15,58"
"low bq, low freq, many artifacts, many samples",UPN2_039,20,31022478,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr655Pro/c.1963A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),8032,107,8186,"0,013071097",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,81",Neutral,15,Damaging,"31,58","14,13"
"low bq, low freq, many artifacts, many samples",UPN2_059,20,31022478,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr655Pro/c.1963A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1737,25,1765,"0,0141643059",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,81",Neutral,15,Damaging,"28,25","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_060,20,31022478,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr655Pro/c.1963A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3448,64,3532,"0,0181200453",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,81",Neutral,15,Damaging,"27,95","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_061,20,31022478,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr655Pro/c.1963A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),2505,34,2551,"0,0133281066",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,81",Neutral,15,Damaging,"28,71","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_062,20,31022478,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr655Pro/c.1963A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3788,56,3871,"0,0144665461",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,81",Neutral,15,Damaging,"28,23","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_063,20,31022478,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr655Pro/c.1963A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3008,47,3074,"0,015289525",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,81",Neutral,15,Damaging,"28,15","18,09"
"low bq, low freq, many artifacts, many samples",UPN2_064,20,31022478,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr655Pro/c.1963A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),2263,34,2308,"0,0147313692",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,81",Neutral,15,Damaging,"29,15",14
"low bq, low freq, many artifacts, many samples",UPN2_065,20,31022478,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr655Pro/c.1963A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1790,40,1837,"0,0217746326",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,81",Neutral,15,Damaging,"29,19","20,2"
"low bq, low freq, many artifacts, many samples",UPN2_068,20,31022478,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr655Pro/c.1963A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1412,26,1445,"0,0179930796",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,81",Neutral,15,Damaging,"28,13","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_069,20,31022478,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr655Pro/c.1963A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),2486,31,2524,"0,0122820919",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,81",Neutral,15,Damaging,"28,5","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_070,20,31022478,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr655Pro/c.1963A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1621,28,1655,"0,016918429",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,81",Neutral,15,Damaging,"28,14","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_071,20,31022478,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr655Pro/c.1963A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4513,87,4628,"0,0187986171",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,81",Neutral,15,Damaging,"28,72","18,55"
"low bq, low freq, many artifacts, many samples",UPN2_072,20,31022478,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr655Pro/c.1963A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3785,57,3862,"0,0147591921",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,81",Neutral,15,Damaging,"28,97","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_073,20,31022478,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr655Pro/c.1963A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),2383,32,2433,"0,0131524866",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,81",Neutral,15,Damaging,"28,19",14
"low bq, low freq, many artifacts, many samples",UPN2_075,20,31022478,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr655Pro/c.1963A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),5268,68,5352,"0,0127055306",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,81",Neutral,15,Damaging,"28,65","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_076,20,31022478,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr655Pro/c.1963A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),2536,34,2581,"0,0131731887",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,81",Neutral,15,Damaging,"28,25","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_077,20,31022478,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr655Pro/c.1963A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),2359,37,2408,"0,0153654485",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,81",Neutral,15,Damaging,"28,36","15,46"
"low bq, low freq, many artifacts, many samples",UPN2_078,20,31022478,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr655Pro/c.1963A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3312,68,3401,"0,0199941194",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,81",Neutral,15,Damaging,"28,78","18,78"
"low bq, low freq, many artifacts, many samples",UPN2_079,20,31022478,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr655Pro/c.1963A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),2365,36,2417,"0,0148944973",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,81",Neutral,15,Damaging,"28,61","18,78"
"low bq, low freq, many artifacts, many samples",UPN2_080,20,31022478,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr655Pro/c.1963A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4384,72,4474,"0,0160929817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,81",Neutral,15,Damaging,"28,65","16,65"
"low bq, low freq, many artifacts, many samples",UPN2_081,20,31022478,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr655Pro/c.1963A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),5179,68,5290,"0,0128544423",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,81",Neutral,15,Damaging,"29,2","14,29"
"low bq, bad alignment, many samples",UPN2_083,20,31022478,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr655Pro/c.1963A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),2894,81,2995,"0,0270450751",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,81",Neutral,15,Damaging,"26,74","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_084,20,31022478,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr655Pro/c.1963A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),2628,33,2676,"0,0123318386",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,81",Neutral,15,Damaging,"28,51","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_087,20,31022478,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr655Pro/c.1963A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),2267,40,2319,"0,0172488141",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,81",Neutral,15,Damaging,"29,01","15,5"
"low bq, low freq, many artifacts, many samples",UPN2_088,20,31022478,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr655Pro/c.1963A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),2086,42,2139,"0,0196353436",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,81",Neutral,15,Damaging,"28,31","14,74"
"low bq, low freq, many artifacts",UPN2_098,20,31022478,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr655Pro/c.1963A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6377,81,6478,"0,0125038592",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"1,81",Neutral,15,Damaging,"30,62","14,74"
"low freq, many artifacts",UPN2_006,20,31022481,G,A,missense_variant(MODERATE|MISSENSE|Gat/Aat|p.Asp656Asn/c.1966G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),3018,44,3072,"0,0143229167",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,"2,48E-005",NO,NO,"-1,24",Neutral,0,Damaging,"34,64","34,82"
"low freq, many artifacts",UPN2_092,20,31022482,A,C,missense_variant(MODERATE|MISSENSE|gAt/gCt|p.Asp656Ala/c.1967A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3516,44,3567,"0,0123352958",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,14",Neutral,0,Damaging,"34,25","29,55"
"low freq, many artifacts",UPN2_044,20,31022482,A,G,missense_variant(MODERATE|MISSENSE|gAt/gGt|p.Asp656Gly/c.1967A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),2944,44,3019,"0,0145743624",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,0,Damaging,"34,08","30,39"
"low bq, low freq, many artifacts",UPN2_079,20,31022485,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu657Val/c.1970A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),2398,25,2454,"0,0101874491",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,87",Deleterious,0,Damaging,"31,68","14,88"
"low freq, many artifacts",UPN2_006,20,31022494,G,A,missense_variant(MODERATE|MISSENSE|gGc/gAc|p.Gly660Asp/c.1979G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),5722,63,5798,"0,0108658158",0,0,0,0,1,0,0,1,2,NO,NO,COSM1025728,endometrium,1,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,0,Damaging,"32,59","33,11"
"inspected, many artifacts",UPN2_067,20,31022494,G,A,missense_variant(MODERATE|MISSENSE|gGc/gAc|p.Gly660Asp/c.1979G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),1811,38,1851,"0,0205294435",0,0,0,0,1,1,0,1,3,NO,NO,COSM1025728,endometrium,1,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,0,Damaging,"31,63","30,26"
"low freq, many artifacts",UPN2_044,20,31022510,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser665Arg/c.1995T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),4967,56,5061,"0,0110650069",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,0,Damaging,"30,76","28,68"
"low bq, low freq, many artifacts, many samples",UPN2_059,20,31022510,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser665Arg/c.1995T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3214,44,3280,"0,0134146341",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,0,Damaging,"28,96","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_060,20,31022510,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser665Arg/c.1995T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),6289,69,6395,"0,0107896794",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,0,Damaging,"28,81","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_061,20,31022510,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser665Arg/c.1995T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),4266,54,4359,"0,0123881624",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,0,Damaging,"28,74",14
"low bq, low freq, many artifacts, many samples",UPN2_062,20,31022510,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser665Arg/c.1995T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),6695,93,6828,"0,0136203866",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,0,Damaging,"28,77","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_063,20,31022510,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser665Arg/c.1995T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),5433,83,5574,"0,0148905633",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,0,Damaging,29,"14,53"
"low bq, low freq, many artifacts, many samples",UPN2_064,20,31022510,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser665Arg/c.1995T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3718,43,3790,"0,0113456464",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,0,Damaging,"29,17","15,86"
"low bq, low freq, many artifacts, many samples",UPN2_065,20,31022510,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser665Arg/c.1995T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),2789,39,2848,"0,0136938202",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,0,Damaging,"28,63","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_067,20,31022510,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser665Arg/c.1995T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),1822,20,1848,"0,0108225108",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,0,Damaging,"29,28",14
"low bq, low freq, many artifacts, many samples",UPN2_068,20,31022510,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser665Arg/c.1995T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),2606,28,2644,"0,0105900151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,0,Damaging,"28,8","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_069,20,31022510,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser665Arg/c.1995T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),4557,69,4674,"0,014762516",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,0,Damaging,"28,94","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_070,20,31022510,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser665Arg/c.1995T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),2947,44,3011,"0,0146130854",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,0,Damaging,"28,75","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_071,20,31022510,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser665Arg/c.1995T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),7503,109,7655,"0,0142390594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,0,Damaging,"28,86","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_072,20,31022510,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser665Arg/c.1995T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),6402,97,6547,"0,0148159462",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,0,Damaging,"28,91","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_075,20,31022510,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser665Arg/c.1995T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9158,113,9307,"0,0121413989",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,0,Damaging,"29,23","15,5"
"low bq, low freq, many artifacts, many samples",UPN2_076,20,31022510,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser665Arg/c.1995T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),4539,59,4634,"0,012731981",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,0,Damaging,"29,15","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_077,20,31022510,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser665Arg/c.1995T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),4416,57,4522,"0,012605042",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,0,Damaging,"29,36","15,98"
"low bq, low freq, many artifacts, many samples",UPN2_078,20,31022510,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser665Arg/c.1995T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),5535,78,5662,"0,0137760509",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,0,Damaging,"28,76","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_080,20,31022510,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser665Arg/c.1995T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),7567,96,7731,"0,0124175398",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,0,Damaging,"29,02","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_081,20,31022510,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser665Arg/c.1995T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),8506,116,8683,"0,013359438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,0,Damaging,"29,11","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_082,20,31022510,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser665Arg/c.1995T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3371,38,3422,"0,0111046172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,0,Damaging,"29,39","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_083,20,31022510,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser665Arg/c.1995T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),5288,94,5405,"0,0173913043",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,0,Damaging,"28,16","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_084,20,31022510,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser665Arg/c.1995T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),4658,53,4729,"0,0112074434",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,0,Damaging,"28,98","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_085,20,31022510,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser665Arg/c.1995T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),1731,22,1766,"0,0124575311",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,0,Damaging,"29,26",14
"low bq, low freq, many artifacts, many samples",UPN2_086,20,31022510,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser665Arg/c.1995T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),1363,20,1391,"0,0143781452",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,0,Damaging,"28,8","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_087,20,31022510,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser665Arg/c.1995T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3922,45,4001,"0,0112471882",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,0,Damaging,29,"14,44"
"low bq, low freq, many artifacts",UPN2_088,20,31022510,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser665Arg/c.1995T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3876,52,3959,"0,01313463",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,21",Neutral,0,Damaging,"29,59","14,77"
"low bq, low freq, many artifacts",UPN2_068,20,31022516,T,G,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp667Glu/c.2001T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),2594,30,2644,"0,0113464448",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,2,Damaging,"30,16","15,9"
"low bq, low freq, many artifacts, many samples",UPN2_059,20,31022524,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu670Ala/c.2009A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3187,69,3280,"0,0210365854",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,0,Damaging,"28,47",14
"low bq, many samples",UPN2_060,20,31022524,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu670Ala/c.2009A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6180,162,6393,"0,0253402159",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,0,Damaging,"28,38","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_092,20,31022524,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu670Ala/c.2009A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6296,68,6400,"0,010625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,0,Damaging,"30,45","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_061,20,31022524,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu670Ala/c.2009A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4243,94,4361,"0,0215546893",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,0,Damaging,"28,55","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_062,20,31022524,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu670Ala/c.2009A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6643,148,6822,"0,0216945177",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,0,Damaging,"28,26","14,92"
"low bq, many samples",UPN2_063,20,31022524,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu670Ala/c.2009A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),5411,124,5573,"0,0222501346",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,0,Damaging,"28,41","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_064,20,31022524,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu670Ala/c.2009A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3694,71,3785,"0,0187582563",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,0,Damaging,"28,42","14,1"
"low bq, many samples",UPN2_065,20,31022524,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu670Ala/c.2009A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),2767,72,2845,"0,0253075571",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,0,Damaging,"28,37","14,1"
"low bq, many samples",UPN2_066,20,31022524,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu670Ala/c.2009A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1522,41,1575,"0,026031746",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,0,Damaging,"28,34","14,95"
"low bq, many samples",UPN2_067,20,31022524,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu670Ala/c.2009A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1784,52,1848,"0,0281385281",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,0,Damaging,"28,8","17,65"
"low bq, low freq, many artifacts, many samples",UPN2_068,20,31022524,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu670Ala/c.2009A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),2575,54,2644,"0,0204236006",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,0,Damaging,"28,61","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_069,20,31022524,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu670Ala/c.2009A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4566,75,4666,"0,0160737248",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,0,Damaging,"28,42","14,19"
"low bq, low freq, many artifacts, many samples",UPN2_070,20,31022524,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu670Ala/c.2009A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),2926,58,3008,"0,0192819149",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,0,Damaging,"28,23","14,48"
"low bq, many samples",UPN2_071,20,31022524,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu670Ala/c.2009A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),7401,192,7652,"0,0250914794",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,0,Damaging,"28,24","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_072,20,31022524,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu670Ala/c.2009A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6352,143,6542,"0,0218587588",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,0,Damaging,"28,6","14,51"
"low bq, many samples",UPN2_073,20,31022524,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu670Ala/c.2009A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4288,105,4423,"0,0237395433",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,0,Damaging,"28,4","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_074,20,31022524,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu670Ala/c.2009A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1865,30,1905,"0,0157480315",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,0,Damaging,"28,38",14
"low bq, low freq, many artifacts, many samples",UPN2_075,20,31022524,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu670Ala/c.2009A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),9067,187,9298,"0,020111852",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,0,Damaging,"28,64","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_076,20,31022524,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu670Ala/c.2009A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4503,97,4632,"0,0209412781",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,0,Damaging,"28,43","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_077,20,31022524,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu670Ala/c.2009A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4393,89,4516,"0,0197077059",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,0,Damaging,"28,68","14,36"
"low bq, many samples",UPN2_078,20,31022524,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu670Ala/c.2009A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),5469,143,5658,"0,0252739484",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,0,Damaging,"28,36","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_079,20,31022524,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu670Ala/c.2009A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4149,91,4281,"0,0212567157",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,0,Damaging,"28,64","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_080,20,31022524,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu670Ala/c.2009A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),7528,144,7732,"0,0186239007",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,0,Damaging,"28,55","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_081,20,31022524,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu670Ala/c.2009A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),8439,181,8680,"0,0208525346",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,0,Damaging,"28,69","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_082,20,31022524,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu670Ala/c.2009A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3341,64,3423,"0,0186970494",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,0,Damaging,"28,58","14,75"
"low bq, many samples",UPN2_083,20,31022524,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu670Ala/c.2009A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),5206,160,5398,"0,0296406076",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,0,Damaging,"28,13","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_084,20,31022524,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu670Ala/c.2009A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4602,94,4728,"0,0198815567",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,0,Damaging,"28,55","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_085,20,31022524,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu670Ala/c.2009A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1723,35,1765,"0,0198300283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,0,Damaging,"28,66","14,2"
"low bq, many samples",UPN2_086,20,31022524,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu670Ala/c.2009A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1349,34,1390,"0,0244604317",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,0,Damaging,"28,64","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_087,20,31022524,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu670Ala/c.2009A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3894,87,4002,"0,0217391304",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,0,Damaging,"28,55","15,59"
"low bq, many samples",UPN2_088,20,31022524,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu670Ala/c.2009A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3838,88,3958,"0,0222334512",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,0,Damaging,"28,61","14,89"
"low bq, low freq, many artifacts",UPN2_098,20,31022524,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu670Ala/c.2009A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),11224,122,11395,"0,0107064502",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,89",Neutral,0,Damaging,"30,24","15,48"
"low bq, low freq, many artifacts, many samples",UPN2_001,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),9236,98,9365,"0,0104644955",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"30,21","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_041,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),22767,245,23204,"0,0105585244",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"29,96","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_089,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),11640,154,11840,"0,0130067568",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"29,69","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_043,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),22426,235,22770,"0,0103205973",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,30,"15,09"
"low bq, low freq, many artifacts, many samples",UPN2_045,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),29121,371,29703,"0,0124903208",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"29,55","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_039,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),11688,130,11860,"0,0109612142",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"30,5","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_090,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),10649,149,10834,"0,0137529998",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"29,43","15,02"
"low bq, many samples",UPN2_059,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3159,92,3277,"0,0280744583",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"28,02","14,9"
"low bq, many samples",UPN2_060,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6109,253,6390,"0,0395931142",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"28,09","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_091,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),9661,136,9825,"0,0138422392",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"29,51","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_092,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6303,69,6398,"0,0107846202",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"29,31","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_093,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),7532,112,7675,"0,0145928339",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"29,49","14,71"
"low bq, many samples",UPN2_061,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4206,139,4362,"0,0318661165",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"28,08","14,3"
"low bq, many samples",UPN2_062,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6545,233,6817,"0,0341792577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"27,83","14,67"
"low bq, many samples",UPN2_063,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),5354,176,5569,"0,0316035195",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"28,08","14,19"
"low bq, many samples",UPN2_064,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3616,132,3783,"0,0348929421",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"27,9","14,65"
"low bq, many samples",UPN2_065,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),2733,95,2840,"0,0334507042",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"28,1","14,89"
"low bq, many samples",UPN2_066,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1500,53,1573,"0,0336935791",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"27,84","14,92"
"low bq, many samples",UPN2_067,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1784,54,1847,"0,0292365999",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"28,34","14,7"
"low bq, many samples",UPN2_068,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),2560,75,2641,"0,028398334",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"28,13","14,61"
"low bq, many samples",UPN2_069,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4508,133,4667,"0,0284979644",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"28,11","14,34"
"low bq, many samples",UPN2_070,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),2882,104,3003,"0,0346320346",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"28,13","14,73"
"low bq, many samples",UPN2_071,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),7334,264,7639,"0,0345594973",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"27,97","14,45"
"low bq, many samples",UPN2_072,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6280,218,6538,"0,0333435301",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"27,95","14,66"
"low bq, many samples",UPN2_073,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4252,150,4422,"0,0339213026",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"28,07","14,72"
"low bq, many samples",UPN2_074,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1825,63,1904,"0,0330882353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"28,07","14,49"
"low bq, many samples",UPN2_075,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),8930,312,9292,"0,0335772708",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"28,06","14,8"
"low bq, many samples",UPN2_076,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4436,182,4634,"0,0392749245",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"28,01","14,46"
"low bq, many samples",UPN2_077,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4332,149,4509,"0,0330450211",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"28,18","14,4"
"low bq, many samples",UPN2_078,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),5455,175,5654,"0,0309515387",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"27,95","14,62"
"low bq, many samples",UPN2_079,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4129,141,4280,"0,0329439252",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"28,02","14,57"
"low bq, many samples",UPN2_080,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),7434,240,7728,"0,0310559006",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"28,01","14,96"
"low bq, many samples",UPN2_081,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),8355,261,8677,"0,0300795206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"28,16","14,38"
"low bq, many samples",UPN2_082,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3288,124,3425,"0,0362043796",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"27,99",14
"low bq, many samples",UPN2_083,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),5135,237,5396,"0,0439214233",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"27,68","14,48"
"low bq, many samples",UPN2_084,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4548,155,4723,"0,0328181241",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"27,9","14,38"
"low bq, many samples",UPN2_085,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1692,62,1761,"0,0352072686",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"28,48","14,76"
"low bq, many samples",UPN2_086,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1331,49,1391,"0,0352264558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"28,22","15,24"
"low bq, many samples",UPN2_087,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3865,124,3999,"0,0310077519",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"28,02","14,44"
"low bq, many samples",UPN2_088,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3812,123,3948,"0,0311550152",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"28,16","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_094,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),12908,157,13123,"0,0119637278",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"29,78","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_095,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),10832,130,11009,"0,0118085203",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"29,56","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_096,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),13747,173,13973,"0,0123810205",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"29,45","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_097,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),14391,194,14612,"0,0132767588",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"29,53","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_098,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),11129,209,11388,"0,0183526519",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"29,23","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_099,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6653,90,6759,"0,0133155792",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"29,28","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_100,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),11989,146,12177,"0,0119898169",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"29,48","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_101,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),10031,106,10173,"0,0104197385",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"29,39","14,12"
"low bq, low freq, many artifacts, many samples",UPN2_102,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),10645,138,10845,"0,012724758",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"29,48","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_103,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),9420,104,9566,"0,0108718378",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"29,25","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_104,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),9447,125,9612,"0,0130045776",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"29,25","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_105,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),11027,145,11204,"0,0129418065",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"29,42","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_106,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),17706,216,17993,"0,0120046685",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"29,66","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_107,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),20438,258,20762,"0,0124265485",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"29,35","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_108,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),15387,205,15657,"0,0130931852",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"29,5","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_109,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),14260,203,14517,"0,0139836054",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"29,6","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_110,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16134,186,16390,"0,0113483832",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"29,76","14,56"
"low bq, low freq, many artifacts",UPN2_111,20,31022536,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His674Pro/c.2021A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),12309,157,12523,"0,012536932",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,27",Neutral,0,Damaging,"29,49","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_060,20,31022542,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu676Ala/c.2027A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6299,78,6389,"0,0122084833",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,2,Damaging,"30,52","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_061,20,31022542,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu676Ala/c.2027A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4297,49,4358,"0,0112436898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,2,Damaging,"30,24","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_062,20,31022542,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu676Ala/c.2027A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6717,77,6814,"0,0113002642",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,2,Damaging,"30,46","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_063,20,31022542,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu676Ala/c.2027A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),5479,65,5565,"0,0116801438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,2,Damaging,"30,46",14
"low bq, low freq, many artifacts, many samples",UPN2_064,20,31022542,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu676Ala/c.2027A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3734,38,3782,"0,0100475939",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,2,Damaging,"30,59","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_065,20,31022542,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu676Ala/c.2027A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),2788,39,2843,"0,0137179036",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,2,Damaging,"30,59","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_067,20,31022542,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu676Ala/c.2027A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1813,21,1846,"0,011375948",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,2,Damaging,"30,72","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_069,20,31022542,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu676Ala/c.2027A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4589,53,4665,"0,0113612004",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,2,Damaging,"30,71","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_070,20,31022542,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu676Ala/c.2027A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),2954,41,3003,"0,0136530137",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,2,Damaging,"30,47",14
"low bq, low freq, many artifacts, many samples",UPN2_071,20,31022542,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu676Ala/c.2027A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),7518,96,7636,"0,0125720272",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,2,Damaging,"30,53","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_072,20,31022542,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu676Ala/c.2027A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6438,72,6537,"0,0110142267",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,2,Damaging,"30,59","14,1"
"low bq, low freq, many artifacts, many samples",UPN2_073,20,31022542,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu676Ala/c.2027A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4352,60,4420,"0,0135746606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,2,Damaging,"30,52",14
"low bq, low freq, many artifacts, many samples",UPN2_074,20,31022542,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu676Ala/c.2027A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1873,23,1904,"0,0120798319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,2,Damaging,"30,58",14
"low bq, low freq, many artifacts, many samples",UPN2_075,20,31022542,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu676Ala/c.2027A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),9156,100,9290,"0,0107642626",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,2,Damaging,"30,47","14,2"
"low bq, low freq, many artifacts, many samples",UPN2_077,20,31022542,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu676Ala/c.2027A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4438,51,4506,"0,0113182423",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,2,Damaging,"30,7","16,47"
"low bq, low freq, many artifacts, many samples",UPN2_078,20,31022542,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu676Ala/c.2027A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),5543,67,5651,"0,0118563086",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,2,Damaging,"30,53","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_081,20,31022542,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu676Ala/c.2027A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),8506,111,8671,"0,0128012917",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,2,Damaging,"30,6","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_082,20,31022542,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu676Ala/c.2027A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3383,44,3440,"0,0127906977",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,2,Damaging,"30,7","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_083,20,31022542,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu676Ala/c.2027A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),5307,72,5388,"0,013363029",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,2,Damaging,"29,98","14,18"
"low bq, low freq, many artifacts, many samples",UPN2_084,20,31022542,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu676Ala/c.2027A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4643,52,4721,"0,0110146155",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,2,Damaging,"30,62",14
"low bq, low freq, many artifacts, many samples",UPN2_087,20,31022542,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu676Ala/c.2027A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3924,54,3995,"0,0135168961",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,2,Damaging,"30,53","14,65"
"low bq, low freq, many artifacts",UPN2_088,20,31022542,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu676Ala/c.2027A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3890,43,3949,"0,0108888326",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,2,Damaging,"30,68","16,88"
"low freq, many artifacts",UPN2_012,20,31022550,G,T,stop_gained(HIGH|NONSENSE|Gga/Tga|p.Gly679*/c.2035G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),9753,155,9928,"0,0156124093",0,0,0,0,1,1,0,1,3,NO,NO,COSM723125,"haematopoietic_and_lymphoid_tissue, lung","4, 1",NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,38","30,3"
"low freq, many artifacts",UPN2_044,20,31022551,G,A,missense_variant(MODERATE|MISSENSE|gGa/gAa|p.Gly679Glu/c.2036G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),4988,52,5050,"0,0102970297",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"33,89",34
"low bq, low freq, many artifacts, many samples",UPN2_041,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),22735,236,23088,"0,0102217602",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,30,"14,54"
"low bq, low freq, many artifacts, many samples",UPN2_089,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),11607,138,11772,"0,0117227319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"29,33","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_050,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),26451,271,26883,"0,0100807202",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,30,"14,18"
"low bq, low freq, many artifacts, many samples",UPN2_056,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6240,64,6316,"0,0101329956",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"30,06","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_090,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),10623,130,10774,"0,012066085",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"29,22","14,3"
"low bq, many samples",UPN2_059,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3137,102,3246,"0,0314232902",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"28,12","14,9"
"low bq, many samples",UPN2_060,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6015,205,6239,"0,0328578298",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"28,1","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_091,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),9606,127,9763,"0,0130082966",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"29,31","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_092,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6247,85,6351,"0,0133837191",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"29,12","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_093,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),7516,81,7623,"0,0106257379",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"29,11","14,16"
"low bq, many samples",UPN2_061,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4105,155,4284,"0,0361811391",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"28,3","14,35"
"low bq, many samples",UPN2_062,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6452,216,6685,"0,0323111444",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"28,03","14,5"
"low bq, many samples",UPN2_063,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),5247,191,5456,"0,0350073314",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"28,23","14,54"
"low bq, many samples",UPN2_064,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3598,112,3722,"0,0300913487",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"28,14","14,89"
"low bq, many samples",UPN2_065,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),2686,94,2793,"0,0336555675",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"28,18","14,65"
"low bq, many samples",UPN2_066,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1490,50,1543,"0,032404407",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"28,07","15,02"
"low bq, many samples",UPN2_067,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1746,65,1816,"0,0357929515",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"28,4","14,42"
"low bq, many samples",UPN2_068,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),2491,96,2590,"0,0370656371",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"28,49","14,35"
"low bq, many samples",UPN2_069,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4448,139,4597,"0,0302371112",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"28,11","14,8"
"low bq, many samples",UPN2_070,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),2834,110,2947,"0,0373260943",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"28,02","14,8"
"low bq, many samples",UPN2_071,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),7224,257,7502,"0,0342575313",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"28,13","14,32"
"low bq, many samples",UPN2_072,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6202,219,6437,"0,03402206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"28,3","14,54"
"low bq, many samples",UPN2_073,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4184,149,4345,"0,03429229",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"28,2","14,87"
"low bq, many samples",UPN2_074,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1796,66,1870,"0,0352941176",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"28,2","14,39"
"low bq, many samples",UPN2_075,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),8823,281,9131,"0,0307742854",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"28,25","14,62"
"low bq, many samples",UPN2_076,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4421,145,4576,"0,0316870629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"28,06","14,56"
"low bq, many samples",UPN2_077,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4282,148,4435,"0,0333709132",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"28,2","14,57"
"low bq, many samples",UPN2_078,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),5344,180,5547,"0,032449973",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"28,14","14,81"
"low bq, many samples",UPN2_079,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4056,133,4212,"0,0315764482",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"28,23","14,1"
"low bq, many samples",UPN2_080,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),7297,275,7602,"0,0361746909",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"28,19","14,84"
"low bq, many samples",UPN2_081,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),8226,251,8510,"0,0294947121",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"28,22","14,59"
"low bq, many samples",UPN2_082,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3266,118,3390,"0,0348082596",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"28,28","14,5"
"low bq, many samples",UPN2_083,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),5031,169,5214,"0,0324127349",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"27,98","14,24"
"low bq, many samples",UPN2_084,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4484,145,4641,"0,0312432665",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"28,33",14
"low bq, many samples",UPN2_085,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1666,68,1736,"0,0391705069",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"28,62","14,1"
"low bq, many samples",UPN2_086,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1324,49,1378,"0,0355587808",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"28,05","14,14"
"low bq, many samples",UPN2_087,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3762,142,3920,"0,0362244898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"28,35","14,34"
"low bq, many samples",UPN2_088,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3733,131,3874,"0,0338151781",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"28,22","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_094,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),12862,155,13046,"0,0118810363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"29,39","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_095,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),10779,129,10941,"0,0117905128",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"29,19","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_096,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),13675,174,13878,"0,0125378297",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"29,24","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_097,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),14333,147,14520,"0,0101239669",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"29,25","14,18"
"low bq, low freq, many artifacts, many samples",UPN2_098,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),11087,123,11255,"0,0109284762",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"29,03","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_099,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6632,76,6716,"0,0113162597",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"28,95","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_100,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),11895,144,12092,"0,0119087",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"29,28","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_102,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),10618,124,10774,"0,0115091888",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"29,29","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_103,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),9350,110,9488,"0,0115935919",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"29,19","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_104,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),9398,114,9537,"0,0119534445",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"29,19","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_105,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),10964,143,11133,"0,0128446959",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"29,1","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_106,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),17633,192,17868,"0,0107454668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"29,27","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_107,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),20288,263,20620,"0,0127546072",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"29,17","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_108,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),15336,165,15554,"0,0106082037",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"29,24","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_109,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),14228,161,14420,"0,0111650485",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"29,2","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_110,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16074,178,16295,"0,0109235962",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"29,37","14,2"
"low bq, low freq, many artifacts",UPN2_111,20,31022559,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser682Arg/c.2044A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),12257,149,12449,"0,0119688328",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,143,Tolerated,"29,25","14,44"
"low freq, many artifacts",UPN2_044,20,31022559,A,G,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser682Gly/c.2044A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),4921,59,5031,"0,0117272908",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,83",Neutral,"0,139",Tolerated,"30,09","32,07"
"low bq, many samples, no database",UPN2_001,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),8362,819,9198,"0,0890410959",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,002",Damaging,"29,77","19,31"
"low bq, many samples, no database",UPN2_014,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),14818,393,15274,"0,0257299987",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,002",Damaging,"30,8","19,3"
"low bq, many samples",UPN2_015,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),18215,430,18720,"0,0229700855",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"30,56","19,09"
"low bq, many samples",UPN2_016,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),10568,244,10860,"0,0224677716",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"31,22","19,11"
"low bq, low freq, many artifacts, many samples",UPN2_017,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3916,75,4004,"0,0187312687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"30,64","21,65"
"low bq, many samples",UPN2_018,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),8804,334,9178,"0,0363913707",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"31,03","19,99"
"low bq, many samples",UPN2_019,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),10282,278,10594,"0,0262412686",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"30,55","19,09"
"low bq, low freq, many artifacts, many samples",UPN2_020,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),9777,219,10048,"0,0217953822",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"30,95","18,91"
"low bq, many samples",UPN2_021,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),10950,258,11274,"0,022884513",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"30,86","18,6"
"low bq, many samples",UPN2_002,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),9501,228,9765,"0,0233486943",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"29,1","18,74"
"low bq, low freq, many artifacts, many samples",UPN2_003,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1795,38,1843,"0,0206185567",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"29,11","16,58"
"low bq, many samples",UPN2_022,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),14910,374,15353,"0,0243600599",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"30,71","19,04"
"low bq, many samples, no database",UPN2_023,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),15234,370,15674,"0,0236059717",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,002",Damaging,"30,69","19,56"
"low bq, many samples",UPN2_041,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),22267,612,23043,"0,0265590418",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"29,25","18,31"
"low bq, many samples",UPN2_024,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),8085,218,8342,"0,0261328219",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"30,89","19,48"
"low bq, many samples",UPN2_025,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),17249,2436,19735,"0,1234355206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"31,22","21,06"
"low bq, many samples, no database",UPN2_026,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16380,407,16859,"0,0241414081",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,002",Damaging,"30,56","20,1"
"low bq, many samples, no database",UPN2_027,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16422,410,16909,"0,0242474422",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,002",Damaging,"30,76","19,9"
"low bq, many samples",UPN2_089,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),11286,427,11744,"0,0363589918",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"28,68","19,1"
"low bq, many samples",UPN2_042,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),32314,895,33418,"0,0267819738",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"29,5","18,08"
"low bq, many samples",UPN2_028,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),11081,276,11428,"0,0241512076",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"30,35","19,74"
"low bq, many samples",UPN2_043,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),21528,889,22527,"0,0394637546",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"29,62","19,17"
"low bq, many samples",UPN2_044,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4872,127,5024,"0,0252786624",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"29,57","18,55"
"low bq, many samples, no database",UPN2_029,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16087,458,16620,"0,02755716",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,002",Damaging,"30,92","20,54"
"low bq, low freq, many artifacts, many samples",UPN2_030,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),15848,352,16293,"0,02160437",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"30,81","19,36"
"low bq, many samples",UPN2_031,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),9853,864,10760,"0,0802973978",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"30,92","20,93"
"low bq, low freq, many artifacts, many samples",UPN2_005,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3206,72,3302,"0,0218049667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"29,33","18,11"
"low bq, many samples, no database",UPN2_045,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),25518,3199,28879,"0,1107725337",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,002",Damaging,"29,78","19,9"
"low bq, many samples",UPN2_032,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),5546,149,5722,"0,0260398462",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"30,65","19,44"
"low bq, many samples",UPN2_046,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),23270,591,24026,"0,0245983518",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"29,39","18,46"
"low bq, many samples, no database",UPN2_033,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),12608,355,13005,"0,0272971934",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,002",Damaging,"31,07","19,94"
"low bq, many samples",UPN2_034,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4553,105,4677,"0,0224502886",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"30,73","19,79"
"low bq, many samples",UPN2_047,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),39379,1093,40685,"0,0268649379",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"29,6","18,04"
"low bq, many samples",UPN2_048,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),29691,720,30593,"0,0235347955",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"29,51","17,94"
"low bq, many samples, no database",UPN2_035,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),13052,525,13647,"0,0384699934",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,002",Damaging,"30,8","20,1"
"low bq, many samples, no database",UPN2_036,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),11216,1192,12470,"0,0955894146",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,002",Damaging,"31,06","21,11"
"low bq, many samples",UPN2_006,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),5609,145,5774,"0,0251125736",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"29,57","18,06"
"low bq, many samples",UPN2_049,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),11332,293,11712,"0,0250170765",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"29,4","17,79"
"low bq, many samples",UPN2_050,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),26019,651,26843,"0,0242521328",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"29,18","17,63"
"low bq, many samples",UPN2_037,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),22989,543,23643,"0,0229666286",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"30,58","19,43"
"low bq, many samples",UPN2_051,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),22228,559,22920,"0,0243891798",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"29,65","18,3"
"low bq, many samples",UPN2_052,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),20775,545,21430,"0,0254316379",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"29,34","18,46"
"low bq, many samples, no database",UPN2_038,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),25203,614,25907,"0,0237001583",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,002",Damaging,"30,74","20,28"
"low bq, many samples, no database",UPN2_039,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),10200,1153,11395,"0,1011847301",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,002",Damaging,"30,89","21,56"
"low bq, many samples",UPN2_053,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),25134,615,25907,"0,0237387579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"29,41","17,39"
"low bq, many samples",UPN2_054,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),14602,386,15069,"0,025615502",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"29,19","17,36"
"low bq, low freq, many artifacts, many samples",UPN2_007,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),24947,525,25567,"0,0205342825",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"29,89","18,21"
"low bq, low freq, many artifacts, many samples",UPN2_008,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),32505,701,33316,"0,0210409413",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"29,62","17,95"
"low bq, many samples",UPN2_009,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),25366,620,26118,"0,0237384179",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"29,64","18,13"
"low bq, many samples",UPN2_010,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),15334,377,15776,"0,0238970588",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"29,44","17,77"
"low bq, many samples",UPN2_011,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),19337,470,19869,"0,0236549399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"29,89","18,49"
"low bq, many samples",UPN2_055,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),30887,786,31826,"0,0246967888",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"29,38","18,43"
"low bq, low freq, many artifacts, many samples",UPN2_056,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6154,121,6302,"0,0192002539",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"29,55","17,4"
"low bq, many samples, no database",UPN2_090,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),10262,455,10751,"0,0423216445",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,002",Damaging,"28,5","19,61"
"low bq, many samples, no database",UPN2_057,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),22141,786,23037,"0,0341190259",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,002",Damaging,"29,48","19,14"
"low bq, many samples, no database",UPN2_058,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),21534,618,22278,"0,0277403717",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,002",Damaging,"29,68","18,77"
"low bq, many samples",UPN2_059,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3018,194,3235,"0,0599690881",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"28,07","17,37"
"low bq, many samples",UPN2_012,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),9527,292,9876,"0,0295666262",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"29,61","18,82"
"low bq, many samples",UPN2_060,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),5612,553,6192,"0,0893087855",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"28,33","20,27"
"low bq, many samples, no database",UPN2_040,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),10458,954,11465,"0,0832097689",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,002",Damaging,"31,04","20,88"
"low bq, low freq, many artifacts, many samples",UPN2_013,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6095,127,6245,"0,020336269",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"29,48","17,62"
"low bq, many samples",UPN2_091,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),9345,353,9736,"0,0362571898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"28,67","19,56"
"low bq, many samples",UPN2_092,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6071,247,6337,"0,0389774341",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"28,4","19,07"
"low bq, many samples, no database",UPN2_093,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),7280,301,7612,"0,0395428271",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,002",Damaging,"28,39","18,87"
"low bq, many samples",UPN2_061,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3973,288,4275,"0,0673684211",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"28,13","18,72"
"low bq, many samples",UPN2_062,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6215,433,6678,"0,0648397724",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"27,93","17,58"
"low bq, many samples",UPN2_063,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),5054,340,5444,"0,0624540779",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"28,01","17,53"
"low bq, many samples",UPN2_064,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3482,221,3719,"0,0594245765",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"27,99","16,8"
"low bq, many samples, no database",UPN2_065,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),2585,191,2788,"0,068507891",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,002",Damaging,"27,94","17,62"
"low bq, many samples",UPN2_066,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1436,91,1538,"0,0591677503",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"28,2","18,37"
"low bq, many samples",UPN2_067,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1712,96,1812,"0,0529801325",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"28,06","17,96"
"low bq, many samples",UPN2_068,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),2413,160,2582,"0,0619674671",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"28,01","18,84"
"low bq, many samples, no database",UPN2_069,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4292,267,4586,"0,0582206716",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,002",Damaging,"28,11","18,39"
"low bq, many samples",UPN2_070,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),2732,186,2938,"0,063308373",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"27,96","17,66"
"low bq, many samples",UPN2_071,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6915,494,7470,"0,0661311914",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"27,99","18,63"
"low bq, many samples",UPN2_072,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6020,379,6421,"0,059025074",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"27,96","17,66"
"low bq, many samples",UPN2_073,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4070,248,4335,"0,0572087659",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"27,9","17,38"
"low bq, many samples",UPN2_074,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1750,101,1864,"0,0541845494",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"27,64","17,49"
"low bq, many samples, no database",UPN2_075,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),8551,508,9110,"0,0557628979",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,002",Damaging,"27,98","17,29"
"low bq, many samples",UPN2_076,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4266,288,4567,"0,0630610904",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"27,85","17,83"
"low bq, many samples, no database",UPN2_077,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4142,267,4433,"0,0602300925",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,002",Damaging,"27,87","18,23"
"low bq, many samples, no database",UPN2_078,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),5170,334,5528,"0,0604196816",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,002",Damaging,"27,89","16,84"
"low bq, many samples",UPN2_079,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3923,248,4198,"0,0590757504",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"27,95","17,59"
"low bq, many samples, no database",UPN2_080,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),7130,432,7589,"0,056924496",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,002",Damaging,"28,03","17,82"
"low bq, many samples, no database",UPN2_081,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),7933,506,8476,"0,0596979707",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,002",Damaging,"28,08","17,76"
"low bq, many samples",UPN2_082,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3159,206,3386,"0,0608387478",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"28,06","17,6"
"low bq, many samples",UPN2_083,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4487,633,5152,"0,1228649068",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"28,73","22,95"
"low bq, many samples",UPN2_084,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4323,285,4630,"0,0615550756",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"28,05","18,74"
"low bq, many samples",UPN2_085,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1619,102,1730,"0,0589595376",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"28,09","18,11"
"low bq, many samples",UPN2_086,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1270,96,1373,"0,0699198835",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"27,92","18,6"
"low bq, many samples",UPN2_087,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3650,248,3915,"0,0633461047",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"28,04","18,21"
"low bq, many samples",UPN2_088,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3638,217,3867,"0,0561158521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"28,02","17,25"
"low bq, many samples, no database",UPN2_094,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),12520,461,13021,"0,0354043468",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,002",Damaging,"28,85","19,55"
"low bq, many samples, no database",UPN2_095,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),10491,393,10922,"0,0359824208",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,002",Damaging,"28,59","19,29"
"low bq, many samples",UPN2_096,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),13260,549,13861,"0,0396075319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"28,53","19,37"
"low bq, many samples, no database",UPN2_097,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),13904,553,14496,"0,0381484547",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,002",Damaging,"28,61","19,47"
"low bq, many samples, no database",UPN2_098,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),10308,801,11157,"0,0717934929",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,002",Damaging,"28,78","21,87"
"low bq, many samples",UPN2_099,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6389,283,6702,"0,0422262011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"28,4","19,15"
"low bq, many samples",UPN2_100,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),11621,424,12068,"0,0351342393",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"28,56","19,23"
"low bq, many samples",UPN2_101,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),8803,1142,9960,"0,1146586345",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"29,14","22,43"
"low bq, many samples, no database",UPN2_102,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),10325,396,10758,"0,036809816",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,002",Damaging,"28,61","19,22"
"low bq, many samples",UPN2_103,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),9083,348,9469,"0,0367515049",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"28,49","19,45"
"low bq, many samples, no database",UPN2_104,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),9117,362,9519,"0,0380292047",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,002",Damaging,"28,54",19
"low bq, many samples, no database",UPN2_105,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),10640,414,11116,"0,0372436128",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,002",Damaging,"28,53","18,92"
"low bq, many samples",UPN2_106,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),17164,610,17830,"0,0342120022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"28,74","19,91"
"low bq, many samples, no database",UPN2_107,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),19754,756,20590,"0,0367168528",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,"0,002",Damaging,"28,52","18,88"
"low bq, many samples",UPN2_108,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),14919,573,15526,"0,0369058354",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"28,55","19,16"
"low bq, many samples",UPN2_109,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),13856,496,14404,"0,0344348792",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"28,6","19,85"
"low bq, many samples",UPN2_110,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),15674,540,16275,"0,0331797235",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"28,85","18,98"
low bq,UPN2_111,20,31022562,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr683Pro/c.2047A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),11950,448,12425,"0,036056338",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,2,Damaging,"28,67","19,33"
"low freq, many artifacts",UPN2_056,20,31022574,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys687Arg/c.2059T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3165,41,3216,"0,0127487562",0,0,0,0,1,0,0,1,2,"0,0116",NO,NO,NA,NA,NO,rs140197482,NO,NO,NO,NO,"-0,57",Neutral,"0,13",Tolerated,"34,33","34,41"
"low freq, many artifacts",UPN2_044,20,31022580,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser689Pro/c.2065T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),2528,26,2562,"0,0101483216",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,"0,126",Tolerated,"34,59","35,5"
"low freq, many artifacts",UPN2_064,20,31022580,T,C,missense_variant(MODERATE|MISSENSE|Tca/Cca|p.Ser689Pro/c.2065T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1915,20,1943,"0,0102933608",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,"0,126",Tolerated,"33,62","32,8"
"Hotspot, inspected, many artifacts",UPN2_057,20,31022592,C,T,stop_gained(HIGH|NONSENSE|Cga/Tga|p.Arg693*/c.2077C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19737,332,20158,"0,0164698879",0,0,0,0,1,1,0,0,2,0,NO,COSM51388,"central_nervous_system, haematopoietic_and_lymphoid_tissue","2, 17",NO,rs373221034,NO,"5,77E-005",NO,NO,NA,NA,NA,NA,"35,35","34,59"
"Hotspot, inspected, many artifacts",UPN2_073,20,31022592,C,T,stop_gained(HIGH|NONSENSE|Cga/Tga|p.Arg693*/c.2077C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5353,55,5413,"0,0101607242",0,0,0,0,1,0,0,1,2,0,NO,COSM51388,"central_nervous_system, haematopoietic_and_lymphoid_tissue","2, 17",NO,rs373221034,NO,"5,77E-005",NO,NO,NA,NA,NA,NA,"35,27","33,71"
"low freq, many artifacts",UPN2_044,20,31022595,A,T,missense_variant(MODERATE|MISSENSE|Aca/Tca|p.Thr694Ser/c.2080A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4448,48,4529,"0,0105983661",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,12",Neutral,"0,007",Damaging,"34,54","34,15"
"inspected, strandbias",UPN2_055,20,31022598,C,T,stop_gained(HIGH|NONSENSE|Caa/Taa|p.Gln695*/c.2083C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),25724,1603,27363,"0,0585827577",1,0,0,0,1,1,0,0,3,NO,NO,COSM1012894,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,46","35,42"
"low freq, many artifacts, many samples",UPN2_044,20,31022624,T,TG,frameshift_variant(HIGH||gag/gGag|p.Glu705fs/c.2113dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|TG|INFO_REALIGN_3_PRIME),4499,92,4528,"0,0203180212",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,6",NA
"low freq, many artifacts, many samples",UPN2_011,20,31022624,T,TG,frameshift_variant(HIGH||gag/gGag|p.Glu705fs/c.2113dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|TG|INFO_REALIGN_3_PRIME),14980,256,15092,"0,0169626292",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,61",NA
"low freq, many artifacts, many samples",UPN2_097,20,31022624,T,TG,frameshift_variant(HIGH||gag/gGag|p.Glu705fs/c.2113dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|TG|INFO_REALIGN_3_PRIME),12944,140,13023,"0,0107502112",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,8",NA
"low freq, many artifacts, many samples",UPN2_006,20,31022633,T,G,missense_variant(MODERATE|MISSENSE|caT/caG|p.His706Gln/c.2118T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),4111,45,4169,"0,0107939554",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,147,Tolerated,"32,78",32
"low freq, many artifacts, many samples",UPN2_006,20,31022634,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr707Pro/c.2119A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4116,42,4168,"0,0100767754",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,5",Neutral,4,Damaging,"32,7","30,45"
"low freq, many artifacts",UPN2_044,20,31022639,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln708His/c.2124G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1916,47,1968,"0,0238821138",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,014",Damaging,"34,65","35,17"
"low freq, many artifacts",UPN2_044,20,31022674,A,G,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp720Gly/c.2159A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3820,40,3880,"0,0103092784",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,"0,007",Damaging,"32,5","34,05"
"many samples, low freq, no database",UPN2_016,20,31022700,A,G,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser729Gly/c.2185A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),7962,88,8076,"0,0108964834",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-1,Neutral,"0,008",Damaging,"34,07","34,38"
"many samples, low freq, no database",UPN2_041,20,31022700,A,G,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser729Gly/c.2185A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),21097,236,21460,"0,0109972041",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-1,Neutral,"0,008",Damaging,"33,4","34,48"
"many samples, low freq, no database",UPN2_048,20,31022700,A,G,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser729Gly/c.2185A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),27478,282,27986,"0,0100764668",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-1,Neutral,"0,008",Damaging,"33,53","34,43"
"many samples, low freq, no database",UPN2_061,20,31022700,A,G,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser729Gly/c.2185A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),7950,83,8105,"0,0102405922",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,-1,Neutral,"0,008",Damaging,"32,34","33,95"
"low freq, many artifacts",UPN2_041,20,31022713,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln733Leu/c.2198A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21061,283,21467,"0,0131830251",0,0,0,0,1,0,0,1,2,0,NO,NO,NO,O,NO,rs370211132,NO,NO,NO,NO,"-1,63",Neutral,"0,005",Damaging,"33,65","25,24"
"low bq, low freq, many artifacts, many samples",UPN2_014,20,31022731,T,A,missense_variant(MODERATE|MISSENSE|cTc/cAc|p.Leu739His/c.2216T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),21502,243,21919,"0,0110862722",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,1,Damaging,"31,42","16,99"
"low bq, low freq, many artifacts, many samples",UPN2_015,20,31022731,T,A,missense_variant(MODERATE|MISSENSE|cTc/cAc|p.Leu739His/c.2216T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),30568,332,31134,"0,0106635832",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,1,Damaging,"31,36","18,08"
"low bq, low freq, many artifacts, many samples",UPN2_016,20,31022731,T,A,missense_variant(MODERATE|MISSENSE|cTc/cAc|p.Leu739His/c.2216T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),14423,171,14716,"0,0116200054",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,1,Damaging,"31,7","18,7"
"low bq, low freq, many artifacts, many samples",UPN2_020,20,31022731,T,A,missense_variant(MODERATE|MISSENSE|cTc/cAc|p.Leu739His/c.2216T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),13433,154,13710,"0,0112326769",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,1,Damaging,"31,35","18,62"
"low bq, low freq, many artifacts, many samples",UPN2_041,20,31022731,T,A,missense_variant(MODERATE|MISSENSE|cTc/cAc|p.Leu739His/c.2216T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),40362,425,41088,"0,0103436526",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,1,Damaging,"32,57","18,84"
"low bq, low freq, many artifacts, many samples",UPN2_027,20,31022731,T,A,missense_variant(MODERATE|MISSENSE|cTc/cAc|p.Leu739His/c.2216T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),27739,304,28278,"0,0107504067",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,1,Damaging,"31,64","17,74"
"low bq, low freq, many artifacts, many samples",UPN2_042,20,31022731,T,A,missense_variant(MODERATE|MISSENSE|cTc/cAc|p.Leu739His/c.2216T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),37066,435,37785,"0,011512505",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,1,Damaging,"32,09","17,75"
"low bq, low freq, many artifacts, many samples",UPN2_028,20,31022731,T,A,missense_variant(MODERATE|MISSENSE|cTc/cAc|p.Leu739His/c.2216T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),19896,203,20294,"0,0100029565",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,1,Damaging,"31,7","18,57"
"low bq, low freq, many artifacts, many samples",UPN2_043,20,31022731,T,A,missense_variant(MODERATE|MISSENSE|cTc/cAc|p.Leu739His/c.2216T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),23087,241,23536,"0,0102396329",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,1,Damaging,"32,31","19,33"
"low bq, low freq, many artifacts, many samples",UPN2_029,20,31022731,T,A,missense_variant(MODERATE|MISSENSE|cTc/cAc|p.Leu739His/c.2216T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),22767,260,23222,"0,0111962794",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,1,Damaging,"31,3","17,75"
"low bq, low freq, many artifacts, many samples",UPN2_030,20,31022731,T,A,missense_variant(MODERATE|MISSENSE|cTc/cAc|p.Leu739His/c.2216T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),24082,266,24532,"0,0108429806",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,1,Damaging,"31,44","18,32"
"low bq, low freq, many artifacts, many samples",UPN2_031,20,31022731,T,A,missense_variant(MODERATE|MISSENSE|cTc/cAc|p.Leu739His/c.2216T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),17002,193,17316,"0,0111457611",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,1,Damaging,"31,7","17,55"
"low bq, low freq, many artifacts, many samples",UPN2_045,20,31022731,T,A,missense_variant(MODERATE|MISSENSE|cTc/cAc|p.Leu739His/c.2216T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),29338,328,29924,"0,0109611015",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,1,Damaging,"31,79","19,04"
"low bq, low freq, many artifacts, many samples",UPN2_032,20,31022731,T,A,missense_variant(MODERATE|MISSENSE|cTc/cAc|p.Leu739His/c.2216T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),8368,95,8532,"0,0111345523",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,1,Damaging,"31,62","16,77"
"low bq, low freq, many artifacts, many samples",UPN2_046,20,31022731,T,A,missense_variant(MODERATE|MISSENSE|cTc/cAc|p.Leu739His/c.2216T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),32264,340,32858,"0,0103475562",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,1,Damaging,"32,3","19,31"
"low bq, low freq, many artifacts, many samples",UPN2_033,20,31022731,T,A,missense_variant(MODERATE|MISSENSE|cTc/cAc|p.Leu739His/c.2216T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),18789,229,19154,"0,0119557273",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,1,Damaging,"31,79","18,06"
"low bq, low freq, many artifacts, many samples",UPN2_034,20,31022731,T,A,missense_variant(MODERATE|MISSENSE|cTc/cAc|p.Leu739His/c.2216T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),6659,80,6798,"0,0117681671",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,1,Damaging,"31,32","17,98"
"low bq, low freq, many artifacts, many samples",UPN2_047,20,31022731,T,A,missense_variant(MODERATE|MISSENSE|cTc/cAc|p.Leu739His/c.2216T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),45986,490,46832,"0,0104629313",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,1,Damaging,"31,98","19,08"
"low bq, low freq, many artifacts, many samples",UPN2_048,20,31022731,T,A,missense_variant(MODERATE|MISSENSE|cTc/cAc|p.Leu739His/c.2216T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),46370,518,47250,"0,010962963",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,1,Damaging,"32,24","19,51"
"low bq, low freq, many artifacts, many samples",UPN2_036,20,31022731,T,A,missense_variant(MODERATE|MISSENSE|cTc/cAc|p.Leu739His/c.2216T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),21329,218,21714,"0,0100396058",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,1,Damaging,"31,19","17,83"
"low bq, low freq, many artifacts, many samples",UPN2_049,20,31022731,T,A,missense_variant(MODERATE|MISSENSE|cTc/cAc|p.Leu739His/c.2216T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),20186,206,20531,"0,0100336077",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,1,Damaging,"32,15","17,63"
"low bq, low freq, many artifacts, many samples",UPN2_050,20,31022731,T,A,missense_variant(MODERATE|MISSENSE|cTc/cAc|p.Leu739His/c.2216T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),29254,329,29805,"0,0110384164",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,1,Damaging,"32,05","18,19"
"low bq, low freq, many artifacts, many samples",UPN2_037,20,31022731,T,A,missense_variant(MODERATE|MISSENSE|cTc/cAc|p.Leu739His/c.2216T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),36356,382,37060,"0,0103076093",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,1,Damaging,"31,42","18,21"
"low bq, low freq, many artifacts, many samples",UPN2_051,20,31022731,T,A,missense_variant(MODERATE|MISSENSE|cTc/cAc|p.Leu739His/c.2216T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),25305,281,25742,"0,0109160127",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,1,Damaging,"32,45","19,02"
"low bq, low freq, many artifacts, many samples",UPN2_052,20,31022731,T,A,missense_variant(MODERATE|MISSENSE|cTc/cAc|p.Leu739His/c.2216T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),25073,271,25548,"0,010607484",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,1,Damaging,"31,82","18,09"
"low bq, low freq, many artifacts, many samples",UPN2_038,20,31022731,T,A,missense_variant(MODERATE|MISSENSE|cTc/cAc|p.Leu739His/c.2216T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),43002,457,43805,"0,010432599",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,1,Damaging,"31,53","18,25"
"low bq, low freq, many artifacts, many samples",UPN2_039,20,31022731,T,A,missense_variant(MODERATE|MISSENSE|cTc/cAc|p.Leu739His/c.2216T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),20971,216,21391,"0,0100977046",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,1,Damaging,"30,99","15,45"
"low bq, low freq, many artifacts, many samples",UPN2_053,20,31022731,T,A,missense_variant(MODERATE|MISSENSE|cTc/cAc|p.Leu739His/c.2216T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),32560,351,33182,"0,0105780242",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,1,Damaging,"32,14","19,15"
"low bq, low freq, many artifacts, many samples",UPN2_054,20,31022731,T,A,missense_variant(MODERATE|MISSENSE|cTc/cAc|p.Leu739His/c.2216T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),19939,216,20315,"0,0106325375",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,1,Damaging,"32,38","19,14"
"low bq, low freq, many artifacts, many samples",UPN2_055,20,31022731,T,A,missense_variant(MODERATE|MISSENSE|cTc/cAc|p.Leu739His/c.2216T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),34594,392,35301,"0,0111045013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,1,Damaging,"32,13","18,69"
"low bq, low freq, many artifacts",UPN2_056,20,31022731,T,A,missense_variant(MODERATE|MISSENSE|cTc/cAc|p.Leu739His/c.2216T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),7959,82,8086,"0,0101409844",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,1,Damaging,"32,33","18,54"
"low bq, low freq, many artifacts, many samples",UPN2_059,20,31022731,T,G,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu739Arg/c.2216T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),29182,393,29832,"0,0131737731",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,2,Damaging,"32,61","15,81"
"low bq, low freq, many artifacts, many samples",UPN2_061,20,31022731,T,G,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu739Arg/c.2216T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),23949,277,24437,"0,0113352703",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,2,Damaging,"32,99","16,58"
"low bq, low freq, many artifacts, many samples",UPN2_062,20,31022731,T,G,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu739Arg/c.2216T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),21178,224,21596,"0,0103722912",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,2,Damaging,"33,18","17,03"
"low bq, low freq, many artifacts, many samples",UPN2_064,20,31022731,T,G,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu739Arg/c.2216T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),26327,340,26961,"0,0126108082",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,2,Damaging,"32,62","16,22"
"low bq, low freq, many artifacts, many samples",UPN2_065,20,31022731,T,G,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu739Arg/c.2216T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),25264,348,25844,"0,0134654078",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,2,Damaging,"32,51","16,27"
"low bq, low freq, many artifacts, many samples",UPN2_066,20,31022731,T,G,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu739Arg/c.2216T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),29473,408,30124,"0,0135440181",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,2,Damaging,"32,39","15,65"
"low bq, low freq, many artifacts, many samples",UPN2_067,20,31022731,T,G,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu739Arg/c.2216T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),29152,350,29761,"0,0117603575",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,2,Damaging,"32,56","16,05"
"low bq, low freq, many artifacts, many samples",UPN2_068,20,31022731,T,G,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu739Arg/c.2216T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),24468,308,25014,"0,0123131047",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,2,Damaging,"32,83","16,36"
"low bq, low freq, many artifacts, many samples",UPN2_069,20,31022731,T,G,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu739Arg/c.2216T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),29356,339,29956,"0,0113165977",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,2,Damaging,"33,2","16,32"
"low bq, low freq, many artifacts, many samples",UPN2_070,20,31022731,T,G,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu739Arg/c.2216T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),18069,232,18475,"0,0125575101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,2,Damaging,"32,88","16,22"
"low bq, low freq, many artifacts, many samples",UPN2_071,20,31022731,T,G,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu739Arg/c.2216T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),18872,210,19232,"0,0109193012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,2,Damaging,"32,81","16,24"
"low bq, low freq, many artifacts, many samples",UPN2_072,20,31022731,T,G,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu739Arg/c.2216T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),19880,245,20298,"0,0120701547",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,2,Damaging,"33,06","16,56"
"low bq, low freq, many artifacts, many samples",UPN2_074,20,31022731,T,G,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu739Arg/c.2216T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),17908,189,18257,"0,0103521937",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,2,Damaging,"32,74","16,14"
"low bq, low freq, many artifacts, many samples",UPN2_076,20,31022731,T,G,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu739Arg/c.2216T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),23868,257,24304,"0,010574391",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,2,Damaging,"33,05","16,06"
"low bq, low freq, many artifacts, many samples",UPN2_077,20,31022731,T,G,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu739Arg/c.2216T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),27679,342,28307,"0,0120818172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,2,Damaging,"32,92","15,77"
"low bq, low freq, many artifacts, many samples",UPN2_078,20,31022731,T,G,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu739Arg/c.2216T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),24096,338,24643,"0,0137158625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,2,Damaging,"32,58","16,05"
"low bq, low freq, many artifacts, many samples",UPN2_080,20,31022731,T,G,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu739Arg/c.2216T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),25093,272,25607,"0,0106220955",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,2,Damaging,"33,01","16,59"
"low bq, low freq, many artifacts, many samples",UPN2_082,20,31022731,T,G,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu739Arg/c.2216T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),33727,367,34382,"0,01067419",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,2,Damaging,"32,6","15,75"
"low bq, low freq, many artifacts, many samples",UPN2_083,20,31022731,T,G,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu739Arg/c.2216T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),30513,355,31103,"0,01141369",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,2,Damaging,"33,04","16,27"
"low bq, low freq, many artifacts, many samples",UPN2_084,20,31022731,T,G,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu739Arg/c.2216T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),26313,305,26926,"0,0113273416",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,2,Damaging,"32,96","15,71"
"low bq, low freq, many artifacts, many samples",UPN2_085,20,31022731,T,G,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu739Arg/c.2216T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),24804,396,25450,"0,0155599214",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,2,Damaging,"32,07","15,82"
"low bq, low freq, many artifacts, many samples",UPN2_086,20,31022731,T,G,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu739Arg/c.2216T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),16315,254,16723,"0,0151886623",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,2,Damaging,"32,21","16,3"
"low bq, low freq, many artifacts, many samples",UPN2_087,20,31022731,T,G,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu739Arg/c.2216T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),33842,444,34623,"0,0128238454",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,2,Damaging,"32,53","15,71"
"low bq, low freq, many artifacts",UPN2_088,20,31022731,T,G,missense_variant(MODERATE|MISSENSE|cTc/cGc|p.Leu739Arg/c.2216T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),25136,266,25620,"0,0103825137",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,2,Damaging,33,"16,08"
"low freq, many artifacts",UPN2_044,20,31022738,TG,T,frameshift_variant(HIGH||ggg/|p.Leu743fs/c.2226delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T|INFO_REALIGN_3_PRIME),3661,49,3742,"0,0130946018",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,67",NA
"low freq, many artifacts",UPN2_006,20,31022742,CT,C,frameshift_variant(HIGH||cta/|p.Leu743fs/c.2228delT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4906,63,4987,"0,0126328454",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,15",NA
"low freq, many artifacts",UPN2_006,20,31022749,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp745Val/c.2234A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4891,76,4987,"0,015239623",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,99",Neutral,1,Damaging,"33,84","34,74"
"low freq, many artifacts",UPN2_056,20,31022764,C,T,missense_variant(MODERATE|MISSENSE|cCc/cTc|p.Pro750Leu/c.2249C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5641,76,5730,"0,0132635253",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,23",Deleterious,"0,001",Damaging,"34,75","35,5"
many samples,UPN2_001,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),7678,188,7899,"0,0238004811",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,89",NA
"low freq, many artifacts, many samples",UPN2_014,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15067,304,15420,"0,0197146563",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,17",NA
"low freq, many artifacts, many samples",UPN2_015,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21642,411,22130,"0,0185720741",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,12",NA
"low freq, many artifacts, many samples",UPN2_016,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10473,213,10714,"0,0198805301",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,04",NA
many samples,UPN2_017,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),6626,159,6813,"0,0233377367",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,16",NA
"low freq, many artifacts, many samples",UPN2_018,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),11890,240,12178,"0,0197076696",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,11",NA
"low freq, many artifacts, many samples",UPN2_019,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),12293,239,12568,"0,01901655",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,14",NA
many samples,UPN2_020,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),9285,289,9604,"0,0300916285",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,12",NA
"low freq, many artifacts, many samples",UPN2_021,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),11726,213,11974,"0,0177885418",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,11",NA
many samples,UPN2_002,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),9611,229,9879,"0,0231804839",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,99",NA
many samples,UPN2_003,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1793,51,1851,"0,0275526742",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,95",NA
many samples,UPN2_022,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16920,400,17374,"0,0230229078",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,12",NA
"low freq, many artifacts, many samples",UPN2_023,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16837,251,17146,"0,0146389829",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,16",NA
"low freq, many artifacts, many samples",UPN2_041,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),29517,589,30304,"0,019436378",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,46",NA
many samples,UPN2_024,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),7673,174,7884,"0,0220700152",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,1",NA
"low freq, many artifacts, many samples",UPN2_025,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21002,378,21459,"0,0176149867",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,08",NA
"low freq, many artifacts, many samples",UPN2_026,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19105,382,19575,"0,0195146871",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,18",NA
"low freq, many artifacts, many samples",UPN2_027,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20205,275,20524,"0,0133989476",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,13",NA
many samples,UPN2_089,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),12486,338,12864,"0,0262748756",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,35,NA
many samples,UPN2_042,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),25316,709,26185,"0,0270765706",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,57",NA
"low freq, many artifacts, many samples",UPN2_028,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),14562,212,14818,"0,014306924",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,15",NA
many samples,UPN2_043,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16078,399,16565,"0,0240869303",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,6",NA
"low freq, many artifacts, many samples",UPN2_044,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3687,39,3743,"0,0104194496",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,81",NA
"low freq, many artifacts, many samples",UPN2_029,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16096,291,16437,"0,0177039606",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,14",NA
"low freq, many artifacts, many samples",UPN2_030,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17191,339,17590,"0,0192723138",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,1",NA
"low freq, many artifacts, many samples",UPN2_031,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),12386,236,12660,"0,0186413902",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,07",NA
many samples,UPN2_005,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),2987,72,3068,"0,0234680574",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,87",NA
many samples,UPN2_045,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19038,602,19766,"0,0304563392",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,7",NA
"low freq, many artifacts, many samples",UPN2_032,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),6007,117,6141,"0,0190522716",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,13",NA
"low freq, many artifacts, many samples",UPN2_046,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22741,427,23287,"0,0183364109",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,52",NA
"low freq, many artifacts, many samples",UPN2_033,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),13702,309,14064,"0,0219709898",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,98",NA
many samples,UPN2_034,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4710,109,4833,"0,0225532795",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,11",NA
many samples,UPN2_047,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),30750,862,31768,"0,0271342231",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,64",NA
"low freq, many artifacts, many samples",UPN2_048,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),32328,711,33213,"0,0214072803",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,58",NA
"low freq, many artifacts, many samples",UPN2_035,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15135,175,15366,"0,0113887804",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,15",NA
"low freq, many artifacts, many samples",UPN2_036,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),14740,284,15074,"0,0188403874",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,18",NA
many samples,UPN2_006,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4859,114,4989,"0,0228502706",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,78",NA
"low freq, many artifacts, many samples",UPN2_049,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),13916,212,14214,"0,0149148727",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,62",NA
"low freq, many artifacts, many samples",UPN2_050,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19873,430,20466,"0,0210104564",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,59",NA
many samples,UPN2_037,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),25927,631,26632,"0,0236933013",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,12",NA
"low freq, many artifacts, many samples",UPN2_051,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17830,375,18316,"0,0204739026",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,46",NA
many samples,UPN2_052,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16324,661,17093,"0,0386708009",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,66",NA
"inspected, many artifacts, many samples",UPN2_038,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),30629,753,31493,"0,0239100753",1,0,0,1,0,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,16",NA
"low freq, many artifacts, many samples",UPN2_039,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),14402,310,14757,"0,0210069797",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,19",NA
many samples,UPN2_053,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22412,553,23084,"0,0239559868",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,58",NA
many samples,UPN2_054,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),14189,337,14604,"0,0230758696",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,53",NA
many samples,UPN2_007,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21208,593,21883,"0,0270986611",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,81",NA
many samples,UPN2_008,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),29808,889,30807,"0,0288570779",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,89",NA
many samples,UPN2_009,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),24000,657,24740,"0,0265561843",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,88",NA
many samples,UPN2_010,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17802,452,18310,"0,024685964",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,74",NA
"many artifacts, many samples",UPN2_011,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19080,418,19569,"0,0213603148",1,0,0,1,0,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,73",NA
many samples,UPN2_055,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),23662,539,24331,"0,0221528092",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,58",NA
"low freq, many artifacts, many samples",UPN2_056,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5583,118,5724,"0,0206149546",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,51",NA
many samples,UPN2_090,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10295,247,10577,"0,0233525574",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,98",NA
"low freq, many artifacts, many samples",UPN2_057,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19157,362,19659,"0,018413958",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,53",NA
"low freq, many artifacts, many samples",UPN2_058,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21594,282,21984,"0,0128275109",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,59",NA
"low freq, many artifacts, many samples",UPN2_059,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),23519,405,24053,"0,0168378165",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,41",NA
many samples,UPN2_012,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10436,260,10748,"0,0241905471",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,77",NA
many samples,UPN2_040,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10438,284,10751,"0,0264161473",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,23",NA
"low freq, many artifacts, many samples",UPN2_013,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),6238,135,6399,"0,0210970464",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,74",NA
"low freq, many artifacts, many samples",UPN2_091,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),8289,128,8454,"0,0151407618",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,99",NA
many samples,UPN2_092,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5869,145,6054,"0,0239511067",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,01",NA
"low freq, many artifacts, many samples",UPN2_093,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),7139,142,7323,"0,01939096",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,1",NA
"low freq, many artifacts, many samples",UPN2_061,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19965,328,20407,"0,0160729162",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,38",NA
"low freq, many artifacts, many samples",UPN2_063,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21666,315,22102,"0,0142521039",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,32",NA
"low freq, many artifacts, many samples",UPN2_064,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21174,436,21722,"0,0200718166",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,5",NA
"low freq, many artifacts, many samples",UPN2_065,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20368,258,20716,"0,0124541417",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,32",NA
"low freq, many artifacts, many samples",UPN2_066,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),23364,345,23837,"0,0144732978",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,37",NA
"low freq, many artifacts, many samples",UPN2_067,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),23446,367,23906,"0,0153517945",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,33",NA
"low freq, many artifacts, many samples",UPN2_068,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20245,282,20629,"0,0136700761",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,37",NA
"low freq, many artifacts, many samples",UPN2_069,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),24881,299,25314,"0,0118116457",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,31",NA
"low freq, many artifacts, many samples",UPN2_070,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15028,196,15292,"0,0128171593",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,33",NA
"low freq, many artifacts, many samples",UPN2_071,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15579,192,15849,"0,012114329",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,32",NA
"low freq, many artifacts, many samples",UPN2_072,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16760,184,17052,"0,0107905231",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,34",NA
"many artifacts, many samples",UPN2_074,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),14563,244,14861,"0,0164188143",1,0,0,1,0,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,38",NA
"low freq, many artifacts, many samples",UPN2_078,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19714,252,20041,"0,0125742228",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,4",NA
"low freq, many artifacts, many samples",UPN2_079,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),13634,159,13872,"0,0114619377",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,32",NA
"low freq, many artifacts, many samples",UPN2_080,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20990,296,21408,"0,0138266069",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,29",NA
"low freq, many artifacts, many samples",UPN2_081,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),25525,360,26049,"0,0138201083",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,36",NA
"low freq, many artifacts, many samples",UPN2_082,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),26915,427,27505,"0,0155244501",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,38",NA
"many artifacts, many samples",UPN2_083,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),25516,436,26065,"0,0167274122",1,0,0,1,0,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,4",NA
"many artifacts, many samples",UPN2_084,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21849,410,22375,"0,0183240223",1,0,0,1,0,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,3",NA
"low freq, many artifacts, many samples",UPN2_085,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19281,302,19668,"0,0153548912",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,43",NA
"low freq, many artifacts, many samples",UPN2_086,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),12881,178,13119,"0,0135681073",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,43",NA
"low freq, many artifacts, many samples",UPN2_087,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),27353,367,27857,"0,0131744265",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,31",NA
"low freq, many artifacts, many samples",UPN2_088,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20937,320,21351,"0,0149875884",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,25",NA
many samples,UPN2_094,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),13940,339,14321,"0,0236715313",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,99",NA
"low freq, many artifacts, many samples",UPN2_095,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10887,231,11155,"0,0207082026",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,98",NA
many samples,UPN2_096,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),11438,307,11789,"0,0260412249",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,11",NA
many samples,UPN2_097,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),13849,343,14242,"0,0240836961",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,08",NA
"low freq, many artifacts, many samples",UPN2_098,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10746,191,10974,"0,0174047749",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,03",NA
many samples,UPN2_099,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),6243,161,6431,"0,0250349868",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,04",NA
many samples,UPN2_100,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),11532,284,11854,"0,0239581576",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,04",NA
many samples,UPN2_101,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),11154,327,11523,"0,0283780266",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,04",NA
many samples,UPN2_102,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),11105,306,11463,"0,0266945826",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,08",NA
many samples,UPN2_103,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),11309,318,11657,"0,0272797461",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,07",NA
"many artifacts, many samples",UPN2_104,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),13826,340,14210,"0,0239268121",1,0,0,1,0,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,07",NA
many samples,UPN2_105,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),13019,330,13400,"0,0246268657",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,97",NA
many samples,UPN2_106,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16505,380,16935,"0,0224387363",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,02",NA
many samples,UPN2_107,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19226,548,19837,"0,0276251449",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,07",NA
"low freq, many artifacts, many samples",UPN2_108,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18576,370,19025,"0,0194480946",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,04",NA
"low freq, many artifacts, many samples",UPN2_109,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16555,366,17004,"0,0215243472",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,35,NA
many samples,UPN2_110,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16917,396,17381,"0,0227834992",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,07",NA
"inspected, strandbias",UPN2_111,20,31022790,TG,T,frameshift_variant(HIGH||tgc/|p.Cys759fs/c.2276delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),14221,435,14716,"0,029559663",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,07",NA
"inspected, many artifacts",UPN2_044,20,31022794,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln760Leu/c.2279A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3666,50,3740,"0,013368984",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,"0,001",Damaging,"31,35","32,8"
"inspected, ins and del, homopolymer 4C",UPN2_070,20,31022801,G,GC,frameshift_variant(HIGH||cta/cCta|p.Leu764fs/c.2290dupC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GC|INFO_REALIGN_3_PRIME),27486,528,27568,"0,0191526407",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,07",NA
"inspected, many artifacts",UPN2_044,20,31022820,A,G,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr769Ala/c.2305A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3581,46,3644,"0,0126234907",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,"0,004",Damaging,"32,08","33,24"
"inspected, many artifacts",UPN2_044,20,31022835,A,G,missense_variant(MODERATE|MISSENSE|Aga/Gga|p.Arg774Gly/c.2320A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3582,44,3639,"0,0120912339",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,25",Neutral,"0,09",Tolerated,"34,58","33,84"
"inspected, many artifacts",UPN2_006,20,31022836,G,A,missense_variant(MODERATE|MISSENSE|aGa/aAa|p.Arg774Lys/c.2321G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),7488,146,7645,"0,0190974493",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,"0,492",Tolerated,"35,01","34,27"
"low bq, low freq, many artifacts",UPN2_050,20,31022856,T,A,missense_variant(MODERATE|MISSENSE|Ttg/Atg|p.Leu781Met/c.2341T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),21999,262,22387,"0,0117032206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,44",Neutral,5,Damaging,"31,95","21,7"
"inspected, many artifacts",UPN2_044,20,31022869,T,A,missense_variant(MODERATE|MISSENSE|gTt/gAt|p.Val785Asp/c.2354T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),3544,70,3629,"0,0192890603",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,053",Tolerated,"31,8","30,17"
"inspected, many artifacts",UPN2_018,20,31022871,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg786*/c.2356A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15505,466,16022,"0,0290850081",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,46","32,96"
"low freq, many artifacts",UPN2_056,20,31022883,G,A,missense_variant(MODERATE|MISSENSE|Gag/Aag|p.Glu790Lys/c.2368G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),3407,36,3446,"0,010446895",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"2,47E-005",NO,NO,"-1,28",Neutral,"0,087",Tolerated,"35,02","34,06"
"low bq, low freq, many artifacts",UPN2_077,20,31022886,T,G,missense_variant(MODERATE|MISSENSE|Tct/Gct|p.Ser791Ala/c.2371T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),18526,191,18783,"0,0101687696",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,67",Neutral,18,Damaging,"30,41","15,54"
"low freq, many artifacts",UPN2_044,20,31022902,G,A,stop_gained(HIGH|NONSENSE|tGg/tAg|p.Trp796*/c.2387G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),5556,83,5655,"0,0146772767",0,0,0,0,1,1,0,1,3,NO,NO,COSM53207,haematopoietic_and_lymphoid_tissue,4,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,19","34,18"
"low freq, many artifacts",UPN2_044,20,31022955,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile814Phe/c.2440A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3754,49,3817,"0,0128373068",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,97",Neutral,"0,09",Tolerated,"34,17","33,63"
"low freq, many artifacts",UPN2_056,20,31022965,T,C,missense_variant(MODERATE|MISSENSE|cTa/cCa|p.Leu817Pro/c.2450T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),2199,29,2231,"0,0129986553",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,58",Neutral,"0,108",Tolerated,"35,08","33,72"
"low bq, many samples",UPN2_001,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15495,969,16476,"0,0588128186",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"29,95","14,3"
"low bq, many samples",UPN2_014,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),25353,1250,26647,"0,0469095958",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"29,09","14,22"
"low bq, many samples",UPN2_015,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),33784,1452,35314,"0,0411168375",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"28,95","14,26"
"low bq, many samples",UPN2_016,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16973,851,17847,"0,047683084",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"29,08","14,14"
"low bq, many samples",UPN2_017,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),11445,566,12032,"0,0470412234",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"29,08","14,29"
"low bq, many samples",UPN2_018,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17069,859,17956,"0,0478391624",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"28,96","14,39"
"low bq, many samples",UPN2_019,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18841,878,19751,"0,0444534454",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"28,98","14,18"
"low bq, many samples",UPN2_020,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16553,829,17401,"0,0476409402",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"29,07","14,3"
"low bq, many samples",UPN2_021,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19448,982,20462,"0,0479913987",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"29,14","14,26"
"low bq, many samples",UPN2_002,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20180,1249,21458,"0,0582067294",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"29,97","14,33"
"low bq, many samples",UPN2_003,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3886,231,4119,"0,0560815732",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"29,95","14,11"
"low bq, many samples",UPN2_022,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),25492,1184,26727,"0,0442997718",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"29,05","14,36"
"low bq, many samples",UPN2_023,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),27891,1355,29292,"0,0462583641",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"29,03","14,32"
"low bq, many samples",UPN2_041,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Cat|p.Asp820His/c.2458G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1023,94,1141,"0,0823838738",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"27,04","14,14"
"low bq, many samples",UPN2_024,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),12763,601,13381,"0,0449144309",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"29,17","14,34"
"low bq, many samples",UPN2_025,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),30369,1478,31908,"0,0463206719",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"29,11","14,24"
"low bq, many samples",UPN2_026,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),29911,1411,31373,"0,0449749785",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"29,06","14,18"
"low bq, many samples",UPN2_004,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3413,209,3631,"0,0575599009",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"29,82","14,19"
"low bq, many samples",UPN2_027,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),32004,1480,33525,"0,0441461596",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"28,98","14,28"
"low bq, many samples, no database",UPN2_089,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18964,1859,20862,"0,0891093855",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,"0,006",Damaging,"29,05","15,08"
"low bq, many samples",UPN2_042,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),30961,2263,33354,"0,0678479343",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"28,99","14,52"
"low bq, many samples",UPN2_028,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22796,973,23809,"0,0408668991",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"28,95","14,27"
"low bq, many samples",UPN2_043,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),26781,2066,28961,"0,0713373157",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"29,06","14,52"
"low bq, many samples",UPN2_044,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),6831,468,7323,"0,0639082343",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"28,96","14,5"
"low bq, many samples",UPN2_029,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),27318,1372,28763,"0,0477001704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"29,11","14,31"
"low bq, many samples",UPN2_030,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),27135,1286,28478,"0,0451576656",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"29,09","14,2"
"low bq, many samples",UPN2_031,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18054,809,18900,"0,0428042328",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"28,93","14,3"
"low bq, many samples",UPN2_005,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),6669,433,7110,"0,0609001406",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"29,94","14,2"
"low bq, many samples",UPN2_045,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),37620,2903,40654,"0,0714074876",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"28,95","14,64"
"low bq, many samples",UPN2_032,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),9647,472,10139,"0,0465529145",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"29,03","14,19"
"low bq, many samples",UPN2_046,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),35344,2603,38073,"0,0683686602",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"28,98","14,88"
"low bq, many samples",UPN2_033,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21035,991,22057,"0,0449290475",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"29,1","14,24"
"low bq, many samples",UPN2_034,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),8148,371,8543,"0,0434273674",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"29,12","14,2"
"low bq, many samples",UPN2_047,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),36993,2789,39904,"0,0698927426",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"29,03","14,38"
"low bq, many samples",UPN2_048,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4572,356,4959,"0,0717886671",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"28,97","14,52"
"low bq, many samples",UPN2_035,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22725,1109,23868,"0,0464638847",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"29,1","14,26"
"low bq, many samples",UPN2_036,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22892,1026,23950,"0,0428392484",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"28,98","14,25"
"low bq, many samples",UPN2_006,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),6945,419,7392,"0,0566829004",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"29,85","14,58"
"low bq, many samples",UPN2_049,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16840,1311,18199,"0,0720369251",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"28,95","14,49"
"low bq, many samples",UPN2_050,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),34915,2601,37627,"0,0691258936",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"28,86","14,39"
"low bq, many samples",UPN2_037,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),42243,1933,44270,"0,0436638807",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,29,"14,25"
"low bq, many samples",UPN2_051,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),27026,2117,29227,"0,0724330243",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"28,92","14,48"
"low bq, many samples",UPN2_052,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),30772,2334,33226,"0,0702461927",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"28,96","14,39"
"low bq, many samples",UPN2_038,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),46452,2121,48655,"0,0435926421",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"28,96","14,36"
"low bq, many samples",UPN2_039,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20879,985,21883,"0,0450121099",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"29,02","14,22"
"low bq, many samples",UPN2_053,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),39769,3063,42976,"0,071272338",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"28,93","14,45"
"low bq, many samples",UPN2_054,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),25331,1908,27349,"0,0697648909",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"28,89","14,38"
"low bq, many samples",UPN2_007,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),44530,2629,47232,"0,055661416",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,30,"14,35"
"low bq, many samples",UPN2_008,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),61332,3777,65225,"0,0579072442",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"30,04","14,46"
"low bq, many samples",UPN2_009,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),52439,3120,55650,"0,05606469",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"29,94","14,38"
"low bq, many samples",UPN2_010,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),34497,2019,36572,"0,0552061687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"29,99","14,31"
"low bq, many samples",UPN2_011,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),39749,2449,42262,"0,0579480384",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"30,1","14,28"
"low bq, many samples",UPN2_055,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),39595,3081,42814,"0,0719624422",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"29,02","14,66"
"low bq, many samples",UPN2_056,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3964,296,4284,"0,0690943044",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"28,87","14,45"
"low bq, many samples",UPN2_090,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17233,1641,18921,"0,0867290312",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"29,07","14,85"
"low bq, many samples",UPN2_057,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),33335,2536,36000,"0,0704444444",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"29,01","14,36"
"low bq, many samples",UPN2_058,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),29968,2355,32441,"0,0725933233",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"29,11","14,6"
"low bq, many samples",UPN2_059,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),12699,962,13699,"0,0702241039",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"30,25","14,65"
"low bq, many samples",UPN2_012,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21730,1376,23163,"0,0594050857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"30,07","14,44"
"low bq, many samples",UPN2_060,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19516,1429,21029,"0,0679537781",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"30,27","14,73"
"low bq, many samples",UPN2_040,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17156,807,17994,"0,0448482828",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"29,08","14,22"
"low bq, many samples",UPN2_013,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),13169,747,13948,"0,0535560654",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"30,07","14,45"
"low bq, many samples, no database",UPN2_091,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),11715,1129,12872,"0,0877097576",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,"0,006",Damaging,"29,09","14,8"
"low bq, many samples",UPN2_092,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10525,980,11529,"0,0850030358",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,29,"14,98"
"low bq, many samples, no database",UPN2_093,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),11476,1074,12580,"0,0853736089",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,"0,006",Damaging,"29,02","15,01"
"low bq, many samples",UPN2_061,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19692,1418,21199,"0,0668899476",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"30,23","14,7"
"low bq, many samples",UPN2_062,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18685,1282,20051,"0,0639369608",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"30,18","14,87"
"low bq, many samples",UPN2_063,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17858,1408,19337,"0,0728137767",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"30,44","14,61"
"low bq, many samples",UPN2_064,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),9981,757,10775,"0,0702552204",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"30,23","14,75"
"low bq, many samples",UPN2_065,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),12013,860,12916,"0,0665840818",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"30,23","14,74"
"low bq, many samples",UPN2_066,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17485,1298,18871,"0,0687827884",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"30,28","14,85"
"low bq, many samples",UPN2_067,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16149,1266,17478,"0,0724339169",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"30,36","14,74"
"low bq, many samples",UPN2_068,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),14121,1095,15262,"0,0717468222",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"30,31","14,86"
"low bq, many samples",UPN2_069,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19455,1437,20968,"0,0685330027",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"30,2","14,78"
"low bq, many samples",UPN2_070,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),12226,862,13140,"0,0656012177",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"30,17","14,91"
"low bq, many samples",UPN2_071,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),14942,1136,16144,"0,0703666997",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"30,31","14,65"
"low bq, many samples",UPN2_072,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),14580,1059,15682,"0,0675296518",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"30,31","14,67"
"low bq, many samples",UPN2_073,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10372,739,11140,"0,0663375224",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"30,2","14,68"
"low bq, many samples",UPN2_074,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10004,750,10798,"0,0694573069",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"30,22","14,54"
"low bq, many samples",UPN2_075,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21266,1593,22944,"0,0694299163",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"30,33","14,73"
"low bq, many samples",UPN2_076,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18038,1326,19436,"0,0682239144",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"30,29","14,72"
"low bq, many samples",UPN2_077,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19134,1350,20560,"0,0656614786",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"30,13","14,74"
"low bq, many samples",UPN2_078,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19254,1375,20702,"0,0664187035",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"30,15","14,73"
"low bq, many samples",UPN2_079,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),12575,872,13497,"0,0646069497",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"30,21","14,69"
"low bq, many samples",UPN2_080,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18739,1368,20184,"0,0677764566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"30,38","14,73"
"low bq, many samples",UPN2_081,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15533,1204,16796,"0,0716837342",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"30,32","14,93"
"low bq, many samples",UPN2_082,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18669,1348,20105,"0,067047998",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"30,36","14,61"
"low bq, many samples",UPN2_083,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21181,1506,22774,"0,0661280407",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"30,2","14,74"
"low bq, many samples",UPN2_084,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19524,1453,21050,"0,0690261283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"30,27","14,79"
"low bq, many samples",UPN2_085,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),14792,1045,15903,"0,0657108722",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"30,09","14,88"
"low bq, many samples",UPN2_086,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10213,712,10970,"0,0649042844",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"30,24","14,68"
"low bq, many samples",UPN2_087,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19764,1589,21428,"0,0741553108",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"30,35","14,79"
"low bq, many samples",UPN2_088,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),14552,1127,15737,"0,0716146661",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"30,31","14,94"
"low bq, many samples, no database",UPN2_094,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22181,2068,24309,"0,0850713727",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,"0,006",Damaging,"29,02","14,97"
"low bq, many samples",UPN2_095,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18532,1640,20223,"0,081095782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"29,06","14,81"
"low bq, many samples, no database",UPN2_096,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20114,1998,22163,"0,0901502504",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,"0,006",Damaging,"29,08","15,18"
"low bq, many samples, no database",UPN2_097,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22861,2189,25108,"0,0871833679",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,"0,006",Damaging,"29,02","14,98"
"low bq, many samples",UPN2_098,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16675,1605,18316,"0,0876283031",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"29,13","14,99"
"low bq, many samples",UPN2_099,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10299,998,11338,"0,0880225789",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,29,"14,81"
"low bq, many samples, no database",UPN2_100,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16092,1641,17777,"0,0923102886",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,"0,006",Damaging,"29,2","15,12"
"low bq, many samples",UPN2_101,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17036,1633,18709,"0,0872841948",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"28,93","14,92"
"low bq, many samples, no database",UPN2_102,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17684,1660,19408,"0,0855317395",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,"0,006",Damaging,"29,02","14,94"
"low bq, many samples, no database",UPN2_103,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17055,1495,18592,"0,0804109294",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,"0,006",Damaging,"28,77","14,99"
"low bq, many samples",UPN2_104,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21683,2068,23809,"0,0868579109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"29,04","14,93"
"low bq, many samples, no database",UPN2_105,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19493,1878,21421,"0,0876709771",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,"0,006",Damaging,"29,03","14,95"
"low bq, many samples, no database",UPN2_106,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22120,2154,24324,"0,0885545141",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,"0,006",Damaging,29,"14,88"
"low bq, many samples, no database",UPN2_107,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),30328,2891,33318,"0,0867699142",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,"0,006",Damaging,"28,99","14,96"
"low bq, many samples, no database",UPN2_108,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),25522,2452,28043,"0,0874371501",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,"0,006",Damaging,"29,01","14,9"
"low bq, many samples, no database",UPN2_109,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),24762,2367,27192,"0,0870476611",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,"0,006",Damaging,"29,04",15
low bq,UPN2_110,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),28971,2277,31321,"0,0726988283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,6,Damaging,"29,57","14,91"
"low bq, many samples, no database",UPN2_111,20,31022973,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp820Tyr/c.2458G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21685,1993,23739,"0,0839546737",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,56",Neutral,"0,006",Damaging,"29,04","14,87"
low bq,UPN2_041,20,31022983,T,A,stop_gained(HIGH|NONSENSE|tTa/tAa|p.Leu823*/c.2468T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),1131,32,1163,"0,0275150473",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,85","24,28"
"low freq, many artifacts",UPN2_041,20,31022994,A,G,missense_variant(MODERATE|MISSENSE|Act/Gct|p.Thr827Ala/c.2479A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),1133,28,1168,"0,0239726027",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,"0,198",Tolerated,"30,55","32,43"
"low freq, many artifacts",UPN2_041,20,31022998,G,A,missense_variant(MODERATE|MISSENSE|gGc/gAc|p.Gly828Asp/c.2483G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),1132,30,1170,"0,0256410256",0,0,0,0,1,1,0,1,3,0,0,NO,NO,O,NO,rs372805894,NO,"2,47E-005",NO,NO,"-0,27",Neutral,"0,543",Tolerated,"31,69","30,13"
"low freq, many artifacts",UPN2_056,20,31023001,A,G,missense_variant(MODERATE|MISSENSE|cAa/cGa|p.Gln829Arg/c.2486A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),4271,45,4338,"0,010373444",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,0,Damaging,"32,87","33,76"
"low freq, many artifacts",UPN2_006,20,31023002,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln829His/c.2487A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),7289,102,7467,"0,0136601045",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,0,Damaging,"33,36","29,37"
"low freq, many artifacts",UPN2_041,20,31023013,G,T,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser833Ile/c.2498G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1121,44,1170,"0,0376068376",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,32",Neutral,"0,001",Damaging,"31,99","31,43"
"low freq, many artifacts, many samples",UPN2_014,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),26570,357,26819,"0,0133114583",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"32,02",NA
"low freq, many artifacts, many samples",UPN2_016,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),17798,248,17950,"0,013816156",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"32,05",NA
"low freq, many artifacts, many samples",UPN2_017,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),11990,163,12096,"0,0134755291",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"32,08",NA
"low freq, many artifacts, many samples",UPN2_018,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),17926,257,18080,"0,0142146018",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"32,02",NA
"low freq, many artifacts, many samples",UPN2_019,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),19681,266,19858,"0,0133951052",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"32,07",NA
"low freq, many artifacts, many samples",UPN2_020,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),17333,227,17492,"0,0129773611",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"32,06",NA
"low freq, many artifacts, many samples",UPN2_021,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),20381,298,20551,"0,0145005109",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"32,05",NA
"low freq, many artifacts, many samples",UPN2_022,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),26683,388,26890,"0,0144291558",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"31,99",NA
"low freq, many artifacts, many samples",UPN2_023,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),29197,429,29484,"0,0145502646",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"31,94",NA
"low freq, many artifacts, many samples",UPN2_024,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),13305,177,13463,"0,013147144",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"32,04",NA
"low freq, many artifacts, many samples",UPN2_025,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),31821,422,32090,"0,0131505142",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"32,01",NA
"low freq, many artifacts, many samples",UPN2_026,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),31278,464,31547,"0,0147082131",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"32,04",NA
"low freq, many artifacts, many samples",UPN2_027,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),33407,498,33683,"0,0147849063",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"31,97",NA
"low freq, many artifacts, many samples",UPN2_089,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),20809,300,20942,"0,0143252793",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"32,82",NA
"low freq, many artifacts, many samples",UPN2_028,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),23740,331,23932,"0,0138308541",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"32,02",NA
"low freq, many artifacts, many samples",UPN2_029,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),28614,379,28897,"0,0131155483",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"31,94",NA
"low freq, many artifacts, many samples",UPN2_030,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),28407,445,28656,"0,0155290341",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"31,98",NA
"low freq, many artifacts, many samples",UPN2_031,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),18863,267,19001,"0,014051892",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,32,NA
"low freq, many artifacts, many samples",UPN2_032,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),10122,133,10197,"0,0130430519",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,32,NA
"low freq, many artifacts, many samples",UPN2_033,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),22007,317,22170,"0,0142986017",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"31,99",NA
"low freq, many artifacts, many samples",UPN2_034,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),8516,111,8601,"0,0129054761",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"32,18",NA
"low freq, many artifacts, many samples",UPN2_035,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),23812,308,24018,"0,0128237155",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"31,97",NA
"low freq, many artifacts, many samples",UPN2_036,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),23833,289,24092,"0,0119956832",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"32,07",NA
"low freq, many artifacts, many samples",UPN2_049,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),18093,193,18349,"0,0105182844",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"32,01",NA
"low freq, many artifacts, many samples",UPN2_037,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),44126,601,44470,"0,013514729",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"32,06",NA
"low freq, many artifacts, many samples",UPN2_038,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),48515,647,48929,"0,0132232418",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"32,1",NA
"low freq, many artifacts, many samples",UPN2_039,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),21783,266,21995,"0,0120936576",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"32,08",NA
"low freq, many artifacts, many samples",UPN2_059,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),13652,151,13830,"0,0109182936",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"31,54",NA
"low freq, many artifacts, many samples",UPN2_060,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),20923,225,21210,"0,0106082037",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"31,61",NA
"low freq, many artifacts, many samples",UPN2_040,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),17953,221,18106,"0,0122058986",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"32,02",NA
"low freq, many artifacts, many samples",UPN2_061,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),21125,239,21386,"0,0111755354",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"31,67",NA
"low freq, many artifacts, many samples",UPN2_074,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),10759,133,10899,"0,0122029544",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"31,59",NA
"low freq, many artifacts, many samples",UPN2_084,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),21030,234,21268,"0,011002445",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"31,61",NA
"low freq, many artifacts, many samples",UPN2_088,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),15687,171,15893,"0,0107594538",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"31,73",NA
"low freq, many artifacts, many samples",UPN2_094,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),24250,429,24417,"0,017569726",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"32,77",NA
"low freq, many artifacts, many samples",UPN2_095,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),20193,355,20305,"0,0174833785",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"32,75",NA
"low freq, many artifacts, many samples",UPN2_096,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),22128,400,22272,"0,0179597701",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"32,77",NA
"low freq, many artifacts, many samples",UPN2_097,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),25120,465,25242,"0,0184216782",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"32,72",NA
"low freq, many artifacts, many samples",UPN2_098,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),18289,344,18409,"0,018686512",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"32,73",NA
"low freq, many artifacts, many samples",UPN2_099,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),11286,211,11367,"0,0185625055",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"32,82",NA
"low freq, many artifacts, many samples",UPN2_101,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),18651,371,18779,"0,0197561105",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"32,67",NA
"low freq, many artifacts, many samples",UPN2_102,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),19343,372,19481,"0,019095529",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"32,72",NA
"low freq, many artifacts, many samples",UPN2_103,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),18514,357,18647,"0,0191451708",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"32,8",NA
"low freq, many artifacts, many samples",UPN2_109,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),27130,509,27275,"0,0186617782",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"32,76",NA
"low freq, many artifacts",UPN2_111,20,31023021,A,ATTTTTTTTT,disruptive_inframe_insertion(MODERATE||act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|ATTTTTTTTT),23728,461,23873,"0,0193105182",0,1,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,87",Deleterious,NA,NA,"32,75",NA
"low freq, many artifacts",UPN2_041,20,31023021,A,G,missense_variant(MODERATE|MISSENSE|Act/Gct|p.Thr836Ala/c.2506A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),1118,28,1170,"0,0239316239",0,0,0,0,1,1,0,1,3,0,NO,NO,NA,NA,NO,rs373580114,NO,"8,24E-006",NO,NO,"-1,07",Neutral,"0,003",Damaging,"31,49","30,14"
"low bq, low freq, many artifacts, many samples",UPN2_050,20,31023021,A,T,missense_variant(MODERATE|MISSENSE|Act/Tct|p.Thr836Ser/c.2506A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),37438,394,37988,"0,0103716963",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,61",Neutral,137,Tolerated,"32,07","23,4"
"low bq, low freq, many artifacts, many samples",UPN2_056,20,31023021,A,T,missense_variant(MODERATE|MISSENSE|Act/Tct|p.Thr836Ser/c.2506A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4270,52,4336,"0,0119926199",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,61",Neutral,137,Tolerated,"32,12","22,37"
"low bq, low freq, many artifacts, many samples",UPN2_001,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16247,297,16614,"0,0178764897",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"33,26","15,58"
"low bq, many samples",UPN2_014,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),25998,672,26810,"0,0250652742",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,94","15,05"
"low bq, many samples",UPN2_015,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),34406,986,35527,"0,0277535396",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,96","15,11"
"low bq, many samples",UPN2_016,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17425,456,17951,"0,0254024845",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,89","14,9"
"low bq, many samples",UPN2_017,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),11725,312,12093,"0,0258000496",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,96","15,58"
"low bq, many samples",UPN2_018,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17550,442,18079,"0,0244482549",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,84","14,6"
"low bq, many samples",UPN2_019,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19285,486,19856,"0,0244762288",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,94","14,91"
"low bq, many samples",UPN2_020,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16974,450,17488,"0,0257319305",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,76","15,31"
"low bq, many samples",UPN2_021,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19937,532,20544,"0,0258956386",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,92","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_002,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21114,400,21618,"0,0185030993",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"33,27","16,27"
"low bq, low freq, many artifacts, many samples",UPN2_003,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4049,84,4142,"0,0202800579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"33,34","15,08"
"low bq, many samples",UPN2_022,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),26023,754,26888,"0,0280422493",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,86","15,1"
"low bq, many samples",UPN2_023,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),28548,836,29482,"0,0283562852",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,83","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_041,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1130,25,1170,"0,0213675214",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,05","14,8"
"low bq, many samples",UPN2_024,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),13056,348,13463,"0,0258486221",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,79","14,93"
"low bq, many samples",UPN2_025,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),31120,843,32089,"0,0262706847",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,82","14,92"
"low bq, many samples",UPN2_026,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),30527,879,31543,"0,0278667216",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,9","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_004,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3571,70,3661,"0,0191204589",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"33,23",14
"low bq, many samples",UPN2_027,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),32571,970,33678,"0,0288021854",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,91","14,91"
"low bq, many samples",UPN2_089,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20095,733,20917,"0,0350432662",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,33,"15,53"
"low bq, many samples",UPN2_042,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),32655,810,33675,"0,0240534521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,52","16,36"
"low bq, many samples",UPN2_028,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),23157,676,23931,"0,0282478793",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,96","15,7"
"low bq, many samples",UPN2_043,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),28363,667,29255,"0,0227995214",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,49","15,17"
"low bq, many samples",UPN2_044,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),7176,170,7410,"0,0229419703",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,72","15,29"
"low bq, many samples",UPN2_029,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),27989,757,28890,"0,0262028384",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,76","14,82"
"low bq, many samples",UPN2_030,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),27697,827,28645,"0,0288706581",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,93","15,11"
"low bq, many samples",UPN2_031,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18369,530,18996,"0,0279006107",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,93","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_005,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),7010,125,7172,"0,0174288901",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,95","14,45"
"low bq, many samples",UPN2_045,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),39749,967,41041,"0,023561804",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,55","15,28"
"low bq, many samples",UPN2_032,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),9902,263,10197,"0,0257918996",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,83","15,08"
"low bq, many samples",UPN2_046,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),37200,971,38451,"0,0252529193",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,55","15,34"
"low bq, many samples",UPN2_033,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21460,601,22168,"0,0271111512",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,83","14,84"
"low bq, many samples",UPN2_034,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),8336,232,8596,"0,0269892973",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,95","15,43"
"low bq, many samples",UPN2_047,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),38984,1019,40331,"0,0252659245",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,41","16,46"
"low bq, low freq, many artifacts, many samples",UPN2_048,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4860,100,5001,"0,0199960008",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,45","16,21"
"low bq, many samples",UPN2_035,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),23289,613,24017,"0,0255235875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,84","14,84"
"low bq, many samples",UPN2_036,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),23391,585,24086,"0,0242879681",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,94","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_006,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),7299,136,7469,"0,0182085955",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"33,4","14,85"
"low bq, many samples",UPN2_049,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17776,453,18387,"0,0246369718",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,56","14,94"
"low bq, many samples",UPN2_050,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),36775,949,37992,"0,0249789429",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,48","16,53"
"low bq, many samples",UPN2_037,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),43097,1187,44464,"0,0266957539",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,95","14,93"
"low bq, many samples",UPN2_051,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),28645,661,29512,"0,0223976687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,52","15,22"
"low bq, many samples",UPN2_052,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),32440,800,33509,"0,0238741831",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,54","16,24"
"low bq, many samples",UPN2_038,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),47442,1300,48922,"0,026572912",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,94","15,46"
"low bq, many samples",UPN2_039,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21370,534,21991,"0,0242826611",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,33,"14,36"
"low bq, many samples",UPN2_053,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),42084,1042,43419,"0,0239987102",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,53","15,22"
"low bq, many samples",UPN2_054,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),26715,686,27610,"0,0248460703",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,63","15,84"
"low bq, low freq, many artifacts, many samples",UPN2_007,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),46476,861,47601,"0,0180878553",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"33,13","15,55"
"low bq, low freq, many artifacts, many samples",UPN2_008,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),64142,1214,65708,"0,0184756803",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"33,2","15,45"
"low bq, low freq, many artifacts, many samples",UPN2_009,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),54739,1015,56079,"0,0180994668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"33,23","15,4"
"low bq, low freq, many artifacts, many samples",UPN2_010,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),35971,672,36822,"0,0182499593",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"33,21","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_011,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),41450,886,42579,"0,0208083797",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,33,"17,18"
"low bq, many samples",UPN2_055,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),41816,1060,43208,"0,024532494",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,45","15,48"
"low bq, low freq, many artifacts, many samples",UPN2_056,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4216,95,4337,"0,0219045423",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,62","15,23"
"low bq, many samples",UPN2_090,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18169,719,18985,"0,0378720042",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"33,02","15,72"
"low bq, many samples",UPN2_057,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),35245,872,36385,"0,02396592",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,51","15,4"
"low bq, many samples",UPN2_058,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),31804,748,32758,"0,0228341169",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,55","14,77"
"low bq, many samples",UPN2_059,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),13406,331,13829,"0,0239352086",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,37","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_012,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22800,423,23347,"0,0181179595",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"33,17","16,06"
"low bq, many samples",UPN2_060,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20542,530,21211,"0,024987035",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,55","15,2"
"low bq, many samples",UPN2_040,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17551,467,18101,"0,0257996796",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,84","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_013,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),13747,247,14058,"0,0175700669",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"33,19","15,14"
"low bq, many samples",UPN2_061,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20740,524,21385,"0,0245031564",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,55","14,95"
"low bq, many samples",UPN2_062,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19643,485,20252,"0,023948252",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,59","15,54"
"low bq, many samples",UPN2_063,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18893,478,19512,"0,024497745",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,39","15,26"
"low bq, many samples",UPN2_064,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10524,254,10859,"0,0233907358",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,54","15,04"
"low bq, many samples",UPN2_065,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),12631,312,13040,"0,0239263804",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,45","16,91"
"low bq, many samples",UPN2_066,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18493,446,19067,"0,0233911995",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,41","14,77"
"low bq, many samples",UPN2_067,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17088,415,17635,"0,0235327474",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,43","15,55"
"low bq, many samples",UPN2_068,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),14981,349,15436,"0,0226094843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,58","15,05"
"low bq, many samples",UPN2_069,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20447,553,21131,"0,0261700819",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,56","15,3"
"low bq, low freq, many artifacts, many samples",UPN2_070,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),12904,278,13254,"0,0209748001",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,64","15,08"
"low bq, many samples",UPN2_071,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15769,400,16284,"0,0245639892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,48","14,75"
"low bq, many samples",UPN2_072,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15324,366,15804,"0,023158694",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,56","15,01"
"low bq, many samples",UPN2_073,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10924,253,11259,"0,0224709122",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,67","14,73"
"low bq, many samples",UPN2_074,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10535,286,10899,"0,0262409395",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,52","15,03"
"low bq, many samples",UPN2_075,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22395,571,23141,"0,0246748196",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,45","15,92"
"low bq, many samples",UPN2_076,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19059,465,19662,"0,0236496796",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,51","15,29"
"low bq, many samples",UPN2_077,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20142,463,20728,"0,0223369355",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,5","15,13"
"low bq, many samples",UPN2_078,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20224,505,20857,"0,0242124946",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,59","15,2"
"low bq, many samples",UPN2_079,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),13167,353,13606,"0,0259444363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,4","15,68"
"low bq, many samples",UPN2_080,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19792,474,20399,"0,0232364332",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,55","15,5"
"low bq, many samples",UPN2_081,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16470,388,16969,"0,0228652248",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,49","15,38"
"low bq, many samples",UPN2_082,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19652,485,20281,"0,0239140082",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,6","15,06"
"low bq, many samples",UPN2_083,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22321,531,22985,"0,0231020231",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,52","15,05"
"low bq, many samples",UPN2_084,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20620,516,21268,"0,0242618018",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,51","14,84"
"low bq, many samples",UPN2_085,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15556,398,16047,"0,0248021437",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,4","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_086,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10752,235,11067,"0,0212343002",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,5","15,15"
"low bq, many samples",UPN2_087,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20927,535,21629,"0,0247353091",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,36","15,4"
low bq,UPN2_088,20,31023022,C,T,missense_variant(MODERATE|MISSENSE|aCt/aTt|p.Thr836Ile/c.2507C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15416,378,15895,"0,0237810632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,49","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_043,20,31023024,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met837Leu/c.2509A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),28860,299,29250,"0,0102222222",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,76",Neutral,14,Damaging,"33,11","18,55"
"low bq, low freq, many artifacts, many samples",UPN2_056,20,31023024,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met837Leu/c.2509A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4277,49,4338,"0,0112955279",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,76",Neutral,14,Damaging,"33,32","17,27"
"low freq, many artifacts, many samples",UPN2_014,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),26017,324,26765,"0,0121053615",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,51",NA
"low freq, many artifacts, many samples",UPN2_016,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17439,221,17926,"0,0123284615",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,44",NA
"low freq, many artifacts, many samples",UPN2_017,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),11750,172,12079,"0,0142395894",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,56",NA
"low freq, many artifacts, many samples",UPN2_019,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19278,262,19831,"0,0132116383",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,54",NA
"low freq, many artifacts, many samples",UPN2_020,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16970,214,17471,"0,0122488696",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,49",NA
"low freq, many artifacts, many samples",UPN2_021,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19950,278,20518,"0,0135490789",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,49",NA
"low freq, many artifacts, many samples",UPN2_022,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),26016,360,26845,"0,0134103185",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,51",NA
"low freq, many artifacts, many samples",UPN2_023,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),28576,407,29436,"0,0138266069",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,43",NA
"low freq, many artifacts, many samples",UPN2_024,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),13058,166,13447,"0,0123447609",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,48",NA
"low freq, many artifacts, many samples",UPN2_025,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),31115,427,32054,"0,0133212704",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,48",NA
"low freq, many artifacts, many samples",UPN2_026,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),30580,440,31505,"0,0139660371",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,5",NA
"low freq, many artifacts, many samples",UPN2_027,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),32604,462,33628,"0,0137385512",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,5",NA
"low freq, many artifacts, many samples",UPN2_089,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20007,292,20910,"0,0139646102",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,58",NA
"low freq, many artifacts, many samples",UPN2_042,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),32478,358,33662,"0,0106351375",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,05",NA
"low freq, many artifacts, many samples",UPN2_028,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),23137,312,23885,"0,0130625916",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,53",NA
"low freq, many artifacts, many samples",UPN2_043,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),28200,319,29230,"0,0109134451",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,01",NA
"low freq, many artifacts, many samples",UPN2_044,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),7125,75,7405,"0,0101282917",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,16",NA
"low freq, many artifacts, many samples",UPN2_029,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),27998,374,28856,"0,0129609093",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,41",NA
"low freq, many artifacts, many samples",UPN2_030,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),27743,393,28617,"0,0137330957",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,48",NA
"low freq, many artifacts, many samples",UPN2_031,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18408,243,18965,"0,0128130767",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,47",NA
"low freq, many artifacts, many samples",UPN2_045,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),39497,474,41010,"0,0115581565",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,06",NA
"low freq, many artifacts, many samples",UPN2_032,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),9902,122,10178,"0,0119866378",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,49",NA
"low freq, many artifacts, many samples",UPN2_046,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),37045,447,38423,"0,0116336569",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,07",NA
"low freq, many artifacts, many samples",UPN2_033,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21469,298,22139,"0,0134604092",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,46",NA
"low freq, many artifacts, many samples",UPN2_034,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),8326,113,8581,"0,0131686284",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,55",NA
"low freq, many artifacts, many samples",UPN2_035,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),23239,325,23984,"0,0135507005",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,49",NA
"low freq, many artifacts, many samples",UPN2_036,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),23389,268,24060,"0,0111388196",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,52",NA
"low freq, many artifacts, many samples",UPN2_049,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17709,222,18371,"0,0120842632",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,01",NA
"low freq, many artifacts, many samples",UPN2_050,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),36613,409,37958,"0,0107750672",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"32,99",NA
"low freq, many artifacts, many samples",UPN2_037,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),43170,584,44408,"0,0131507836",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,56",NA
"low freq, many artifacts, many samples",UPN2_051,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),28471,328,29485,"0,0111243005",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,09",NA
"low freq, many artifacts, many samples",UPN2_052,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),32274,366,33487,"0,0109296145",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,13",NA
"low freq, many artifacts, many samples",UPN2_038,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),47455,590,48842,"0,0120797674",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,54",NA
"low freq, many artifacts, many samples",UPN2_039,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21325,263,21963,"0,0119746847",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,55",NA
"low freq, many artifacts, many samples",UPN2_053,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),41865,516,43381,"0,0118946082",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,03",NA
"low freq, many artifacts, many samples",UPN2_055,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),41598,488,43187,"0,0112996967",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"32,99",NA
"low freq, many artifacts, many samples",UPN2_057,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),35068,398,36358,"0,0109466967",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,03",NA
"low freq, many artifacts, many samples",UPN2_058,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),31598,338,32743,"0,0103228171",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,02",NA
"low freq, many artifacts, many samples",UPN2_059,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),13317,163,13820,"0,0117945007",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"32,85",NA
"low freq, many artifacts, many samples",UPN2_060,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20496,226,21205,"0,0106578637",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"32,83",NA
"low freq, many artifacts, many samples",UPN2_040,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17544,223,18082,"0,0123327066",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,44",NA
"low freq, many artifacts, many samples",UPN2_061,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20649,229,21373,"0,0107144528",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"32,83",NA
"low freq, many artifacts, many samples",UPN2_074,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10518,136,10893,"0,0124850822",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"32,66",NA
"low freq, many artifacts, many samples",UPN2_084,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20539,232,21262,"0,0109114853",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"32,81",NA
"low freq, many artifacts, many samples",UPN2_088,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15373,188,15891,"0,0118305959",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"32,76",NA
"low freq, many artifacts, many samples",UPN2_094,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),23264,402,24368,"0,0164970453",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,59",NA
"low freq, many artifacts, many samples",UPN2_095,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19324,323,20271,"0,015934093",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,57",NA
"low freq, many artifacts, many samples",UPN2_096,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21155,385,22239,"0,0173119295",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,53",NA
"low freq, many artifacts, many samples",UPN2_097,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),23977,448,25183,"0,0177897788",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,52",NA
"low freq, many artifacts, many samples",UPN2_098,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17471,318,18367,"0,0173136604",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,51",NA
"low freq, many artifacts, many samples",UPN2_099,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10805,198,11339,"0,0174618573",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,62",NA
"low freq, many artifacts, many samples",UPN2_101,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17847,333,18741,"0,0177685289",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,59",NA
"low freq, many artifacts, many samples",UPN2_102,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18505,349,19424,"0,0179674629",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,58",NA
"low freq, many artifacts, many samples",UPN2_103,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17754,319,18606,"0,017145007",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,6",NA
"low freq, many artifacts, many samples",UPN2_109,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),25898,447,27208,"0,0164289915",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,58",NA
"low freq, many artifacts",UPN2_111,20,31023025,TGAAGGATCC,T,disruptive_inframe_deletion(MODERATE||atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22695,423,23825,"0,0177544596",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,44",Deleterious,NA,NA,"33,58",NA
"low freq, many artifacts",UPN2_048,20,31023026,G,C,missense_variant(MODERATE|MISSENSE|atG/atC|p.Met837Ile/c.2511G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4775,59,4998,"0,0118047219",0,0,0,0,0,0,0,1,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,33,"31,1"
"low bq, low freq, many artifacts, many samples",UPN2_001,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16193,213,16586,"0,012842156",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"33,77","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_015,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),34410,389,35478,"0,0109645414",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"33,56","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_002,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21018,283,21580,"0,0131139944",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"33,76","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_003,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4030,49,4135,"0,0118500605",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"33,87","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_022,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),26016,304,26845,"0,011324269",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"33,51","15,05"
"low bq, many samples",UPN2_041,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1117,30,1168,"0,0256849315",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"32,07","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_024,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),13058,144,13447,"0,0107087083",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"33,48","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_004,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3556,62,3656,"0,0169584245",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"33,67","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_042,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),32478,617,33662,"0,0183292734",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"33,05","15,17"
"low bq, low freq, many artifacts, many samples",UPN2_028,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),23137,252,23885,"0,0105505547",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"33,53","15,53"
"low bq, low freq, many artifacts, many samples",UPN2_043,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),28200,531,29230,"0,0181662675",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"33,01","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_044,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),7125,138,7405,"0,0186360567",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"33,16","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_029,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),27998,305,28856,"0,0105697255",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"33,41","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_030,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),27743,308,28617,"0,0107628333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"33,48","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_031,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18408,204,18965,"0,010756657",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"33,47","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_005,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),6973,105,7165,"0,0146545708",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"33,47","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_045,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),39497,768,41010,"0,0187271397",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"33,06","15,53"
"low bq, low freq, many artifacts, many samples",UPN2_032,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),9902,103,10178,"0,0101198664",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"33,49","14,07"
"low bq, low freq, many artifacts, many samples",UPN2_046,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),37045,657,38423,"0,0170991333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"33,07","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_047,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),38854,779,40310,"0,0193252295",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"32,98","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_048,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atC|p.Met837Ile/c.2511G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4775,101,4998,"0,0202080832",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,33,"14,14"
"low bq, low freq, many artifacts, many samples",UPN2_035,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),23239,268,23984,"0,0111741161",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"33,49","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_036,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),23389,245,24060,"0,0101828761",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"33,52","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_006,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),7283,89,7461,"0,0119286959",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"33,81","14,15"
"low bq, low freq, many artifacts, many samples",UPN2_049,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17709,328,18371,"0,0178542268",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"33,01","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_050,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),36613,736,37958,"0,0193898519",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"32,99","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_051,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),28471,517,29485,"0,0175343395",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"33,09","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_052,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),32274,640,33487,"0,0191118942",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"33,13","15,54"
"low bq, low freq, many artifacts, many samples",UPN2_038,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),47455,538,48842,"0,0110151099",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"33,54","14,13"
"low bq, low freq, many artifacts, many samples",UPN2_039,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21325,258,21963,"0,0117470291",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"33,55","15,71"
"low bq, low freq, many artifacts, many samples",UPN2_053,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),41865,735,43381,"0,0169429013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"33,03","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_054,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),26586,510,27592,"0,0184836184",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"33,13","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_007,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),46275,652,47517,"0,013721405",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"33,64","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_008,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),63942,768,65545,"0,0117171409",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"33,69","14,18"
"low bq, low freq, many artifacts, many samples",UPN2_009,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),54595,729,55957,"0,0130278607",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"33,72","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_010,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),35827,464,36747,"0,0126268811",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"33,71","14,08"
"low bq, low freq, many artifacts, many samples",UPN2_011,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),41355,639,42516,"0,0150296359",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"33,59","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_055,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),41598,820,43187,"0,0189871952",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"32,99","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_056,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4203,72,4337,"0,0166013373",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"33,03",14
"low bq, low freq, many artifacts, many samples",UPN2_057,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),35068,669,36358,"0,0184003521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"33,03","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_058,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),31598,607,32743,"0,0185383135",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"33,02","15,3"
"low bq, low freq, many artifacts, many samples",UPN2_059,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),13317,260,13820,"0,018813314",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"32,85","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_012,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22780,277,23304,"0,0118863714",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"33,64","14,03"
"low bq, low freq, many artifacts, many samples",UPN2_060,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20496,378,21205,"0,0178259844",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"32,83","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_040,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17544,192,18082,"0,0106182944",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"33,44","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_013,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),13689,179,14040,"0,0127492877",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"33,68","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_061,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20649,383,21373,"0,0179198054",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"32,83","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_062,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19573,331,20245,"0,016349716",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"32,87","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_063,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18802,389,19502,"0,0199466721",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"32,77","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_064,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10477,200,10854,"0,0184263866",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"32,85","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_065,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),12602,246,13041,"0,0188635841",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"32,86","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_066,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18454,322,19046,"0,016906437",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"32,75","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_067,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17013,327,17629,"0,0185489818",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"32,77","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_068,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),14934,261,15429,"0,0169161968",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"32,89","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_069,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20382,372,21121,"0,0176128024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"32,84","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_070,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),12828,215,13245,"0,0162325406",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"32,86","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_071,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15731,305,16280,"0,0187346437",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"32,86","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_072,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15291,263,15799,"0,0166466232",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"32,95","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_073,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10885,181,11257,"0,0160788842",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"32,88","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_074,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10518,182,10893,"0,0167079776",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"32,66","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_075,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22358,400,23122,"0,0172995416",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"32,74","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_076,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18981,359,19647,"0,0182725098",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"32,81","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_077,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20009,389,20719,"0,0187750374",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"32,84","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_078,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20149,354,20847,"0,0169808606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"32,83","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_079,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),13132,247,13598,"0,0181644359",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"32,76","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_080,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19735,363,20395,"0,01779848",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"32,82","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_081,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16401,287,16962,"0,0169201745",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"32,75","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_082,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19611,335,20274,"0,0165236263",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"32,91","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_083,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22232,376,22974,"0,0163663272",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"32,78","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_084,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20539,386,21262,"0,018154454",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"32,81","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_085,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15504,288,16038,"0,0179573513",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"32,64","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_086,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10730,175,11060,"0,0158227848",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"32,71","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_087,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20867,452,21627,"0,0208998012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"32,74","14,81"
"low bq, low freq, many artifacts",UPN2_088,20,31023026,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met837Ile/c.2511G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15373,251,15891,"0,0157951041",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,8,Damaging,"32,76","14,47"
"inspected, bad alignment, different dels",UPN2_110,20,31023026,GA,G,frameshift_variant(HIGH||aag/|p.Lys838fs/c.2513delA|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G|INFO_REALIGN_3_PRIME),25562,4296,30545,"0,1406449501",1,1,0,1,0,1,0,1,5,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,62",NA
"low bq, low freq, many artifacts, many samples",UPN2_001,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16049,251,16417,"0,0152890297",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,6","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_014,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),25766,373,26326,"0,0141685026",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,62","17,3"
"low bq, low freq, many artifacts, many samples",UPN2_015,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),34080,477,34851,"0,0136868383",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,67","16,1"
"low bq, low freq, many artifacts, many samples",UPN2_016,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17249,224,17633,"0,0127034538",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,51","15,48"
"low bq, low freq, many artifacts, many samples",UPN2_017,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),11625,157,11861,"0,013236658",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,7","16,41"
"low bq, low freq, many artifacts, many samples",UPN2_018,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17351,245,17740,"0,0138105975",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,59","16,36"
"low bq, low freq, many artifacts, many samples",UPN2_019,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19086,274,19499,"0,0140520027",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,7","16,26"
"low bq, low freq, many artifacts, many samples",UPN2_020,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16857,192,17174,"0,0111796902",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,6","17,73"
"low bq, low freq, many artifacts, many samples",UPN2_021,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19756,246,20162,"0,0122011705",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,66","15,3"
"low bq, low freq, many artifacts, many samples",UPN2_002,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20859,347,21334,"0,0162651167",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,53","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_003,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4001,54,4087,"0,0132126254",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,55","16,54"
"low bq, low freq, many artifacts, many samples",UPN2_022,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),25769,373,26359,"0,0141507644",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,63","16,4"
"low bq, low freq, many artifacts, many samples",UPN2_023,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),28265,406,28905,"0,0140460128",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,59","16,19"
"low bq, many samples",UPN2_041,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1112,29,1148,"0,025261324",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,09","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_024,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),12929,178,13216,"0,013468523",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,63","16,54"
"low bq, low freq, many artifacts, many samples",UPN2_025,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),30834,420,31489,"0,013337991",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,6","15,92"
"low bq, low freq, many artifacts, many samples",UPN2_026,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),30255,435,30915,"0,0140708394",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,66","15,81"
"low bq, low freq, many artifacts, many samples",UPN2_004,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3529,69,3618,"0,0190713101",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,62","16,41"
"low bq, low freq, many artifacts, many samples",UPN2_027,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),32283,454,32998,"0,0137584096",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,67","15,95"
"low bq, low freq, many artifacts, many samples",UPN2_042,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),32318,605,33176,"0,0182360743",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,33,"16,35"
"low bq, low freq, many artifacts, many samples",UPN2_028,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22940,331,23460,"0,0141091219",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,65","16,4"
"low bq, low freq, many artifacts, many samples",UPN2_043,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),27992,545,28785,"0,0189334723",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,94","16,39"
"low bq, low freq, many artifacts, many samples",UPN2_044,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),7107,150,7302,"0,0205423172",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,94","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_029,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),27710,419,28370,"0,0147691223",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,61","16,13"
"low bq, low freq, many artifacts, many samples",UPN2_030,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),27442,410,28098,"0,0145917859",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,64","16,5"
"low bq, low freq, many artifacts, many samples",UPN2_031,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18216,279,18640,"0,0149678112",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,64","15,7"
"low bq, low freq, many artifacts, many samples",UPN2_005,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),6930,104,7085,"0,0146788991",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,31","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_045,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),39315,776,40367,"0,0192236233",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,93","16,64"
"low bq, low freq, many artifacts, many samples",UPN2_032,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),9827,138,10020,"0,0137724551",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,59","15,96"
"low bq, low freq, many artifacts, many samples",UPN2_046,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),36897,642,37793,"0,0169872728",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,98","16,17"
"low bq, low freq, many artifacts, many samples",UPN2_033,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21244,314,21728,"0,0144513991",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,6","17,36"
"low bq, low freq, many artifacts, many samples",UPN2_034,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),8267,96,8429,"0,0113892514",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,65",14
"low bq, low freq, many artifacts, many samples",UPN2_047,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),38684,743,39743,"0,0186951161",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,92","16,24"
"low bq, low freq, many artifacts, many samples",UPN2_048,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4813,94,4938,"0,019036047",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,92","15,46"
"low bq, low freq, many artifacts, many samples",UPN2_035,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),23018,355,23553,"0,0150723899",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,6","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_036,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),23194,342,23685,"0,0144395187",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,62","17,22"
"low bq, low freq, many artifacts, many samples",UPN2_006,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),7218,114,7383,"0,0154408777",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,69","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_049,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17577,312,18068,"0,0172680983",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,93","15,84"
"low bq, low freq, many artifacts, many samples",UPN2_050,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),36368,714,37427,"0,0190771368",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,96","16,28"
"low bq, low freq, many artifacts, many samples",UPN2_037,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),42730,602,43650,"0,0137915235",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,66","17,17"
"low bq, low freq, many artifacts, many samples",UPN2_051,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),28325,499,29040,"0,0171831956",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,33,"15,36"
"low bq, low freq, many artifacts, many samples",UPN2_052,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),32074,614,32990,"0,0186117005",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,94","16,12"
"low bq, low freq, many artifacts, many samples",UPN2_038,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),47009,673,48041,"0,0140088674",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,66","16,75"
"low bq, low freq, many artifacts, many samples",UPN2_039,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21194,280,21616,"0,0129533679",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,63","16,09"
"low bq, low freq, many artifacts, many samples",UPN2_053,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),41530,819,42691,"0,0191843714",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,96","16,78"
"low bq, low freq, many artifacts, many samples",UPN2_054,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),26475,486,27162,"0,0178926441",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,98","16,89"
"low bq, low freq, many artifacts, many samples",UPN2_007,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),45859,823,47012,"0,0175061686",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,51","15,56"
"low bq, low freq, many artifacts, many samples",UPN2_008,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),63291,1078,64818,"0,0166311827",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,55","15,51"
"low bq, low freq, many artifacts, many samples",UPN2_009,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),54075,923,55382,"0,0166660648",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,54","15,92"
"low bq, low freq, many artifacts, many samples",UPN2_010,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),35496,614,36352,"0,0168904049",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,57","15,83"
"low bq, low freq, many artifacts, many samples",UPN2_011,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),41036,690,42067,"0,0164024057",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,48","15,91"
"low bq, low freq, many artifacts, many samples",UPN2_055,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),41455,747,42532,"0,0175632465",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,95","16,53"
"low bq, low freq, many artifacts, many samples",UPN2_056,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4178,64,4281,"0,0149497781",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,94","15,45"
"low bq, low freq, many artifacts, many samples",UPN2_057,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),34812,712,35816,"0,0198793835",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,98","17,12"
"low bq, low freq, many artifacts, many samples",UPN2_058,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),31406,556,32273,"0,0172280234",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,99","15,73"
"low bq, low freq, many artifacts, many samples",UPN2_059,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),13395,146,13612,"0,0107258301",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,48","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_012,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22465,417,23088,"0,0180613306",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,53","16,25"
"low bq, low freq, many artifacts, many samples",UPN2_060,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20505,258,20908,"0,0123397742",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,51","16,36"
"low bq, low freq, many artifacts, many samples",UPN2_040,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17392,267,17784,"0,0150134953",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,67","17,1"
"low bq, low freq, many artifacts, many samples",UPN2_013,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),13548,245,13880,"0,0176512968",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,53","16,58"
"low bq, low freq, many artifacts, many samples",UPN2_061,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20623,282,21076,"0,013380148",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,66","16,51"
"low bq, low freq, many artifacts, many samples",UPN2_062,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19581,249,19967,"0,0124705765",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,55","16,38"
"low bq, low freq, many artifacts, many samples",UPN2_063,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18921,223,19247,"0,0115862212",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,55","15,7"
"low bq, low freq, many artifacts, many samples",UPN2_064,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10484,153,10719,"0,0142737196",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,57","17,09"
"low bq, low freq, many artifacts, many samples",UPN2_065,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),12637,161,12880,"0,0125",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,51","16,02"
"low bq, low freq, many artifacts, many samples",UPN2_066,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18439,239,18813,"0,0127039813",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,56","17,47"
"low bq, low freq, many artifacts, many samples",UPN2_067,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17081,215,17383,"0,0123684059",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,56","16,52"
"low bq, low freq, many artifacts, many samples",UPN2_068,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),14925,197,15225,"0,0129392447",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,49","16,32"
"low bq, low freq, many artifacts, many samples",UPN2_069,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20433,246,20811,"0,0118206718",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,49","16,58"
"low bq, low freq, many artifacts, many samples",UPN2_070,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),12816,149,13073,"0,0113975369",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,5","15,6"
"low bq, low freq, many artifacts, many samples",UPN2_071,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15807,168,16073,"0,0104523113",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,59","17,49"
"low bq, low freq, many artifacts, many samples",UPN2_072,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15336,171,15600,"0,0109615385",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,65","15,86"
"low bq, low freq, many artifacts, many samples",UPN2_073,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10880,154,11093,"0,0138826287",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,62","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_074,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10533,135,10730,"0,0125815471",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,51","15,83"
"low bq, low freq, many artifacts, many samples",UPN2_075,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22395,271,22823,"0,0118739868",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,56","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_076,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19016,231,19392,"0,0119121287",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,52","16,66"
"low bq, low freq, many artifacts, many samples",UPN2_077,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20060,259,20456,"0,0126613219",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,51","16,61"
"low bq, low freq, many artifacts, many samples",UPN2_078,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20165,267,20569,"0,0129806991",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,55","16,28"
"low bq, low freq, many artifacts, many samples",UPN2_079,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),13141,183,13413,"0,0136434802",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,59","15,66"
"low bq, low freq, many artifacts, many samples",UPN2_080,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19755,264,20146,"0,0131043383",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,53","16,63"
"low bq, low freq, many artifacts, many samples",UPN2_081,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16434,200,16738,"0,0119488589",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,66","16,51"
"low bq, low freq, many artifacts, many samples",UPN2_082,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19627,251,20006,"0,0125462361",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,58","16,67"
"low bq, low freq, many artifacts, many samples",UPN2_083,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22239,280,22666,"0,0123533045",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,52","16,58"
"low bq, low freq, many artifacts, many samples",UPN2_084,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20562,268,20970,"0,0127801621",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,47",16
"low bq, low freq, many artifacts, many samples",UPN2_085,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15500,204,15820,"0,0128950695",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,41","16,44"
"low bq, low freq, many artifacts, many samples",UPN2_086,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10712,139,10922,"0,0127266068",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,48","16,15"
"low bq, low freq, many artifacts, many samples",UPN2_087,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20937,291,21367,"0,0136191323",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,48","16,52"
"low bq, low freq, many artifacts",UPN2_088,20,31023027,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys838*/c.2512A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15386,186,15653,"0,0118827062",0,0,0,0,1,0,0,0,1,NO,NO,COSM145115,haematopoietic_and_lymphoid_tissue,3,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,59","15,87"
"low bq, low freq, many artifacts, many samples",UPN2_001,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16073,220,16361,"0,0134466108",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,82","16,16"
"low bq, low freq, many artifacts, many samples",UPN2_014,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),25778,338,26217,"0,0128923981",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"34,21","15,42"
"low bq, low freq, many artifacts, many samples",UPN2_015,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),34030,485,34681,"0,0139846025",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"34,24","15,52"
"low bq, low freq, many artifacts, many samples",UPN2_016,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17260,215,17554,"0,0122479207",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"34,16","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_017,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),11633,153,11824,"0,0129397835",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"34,28","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_018,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17337,229,17663,"0,012964955",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"34,16","15,59"
"low bq, low freq, many artifacts, many samples",UPN2_019,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19110,246,19428,"0,0126621371",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"34,19","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_020,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16805,208,17100,"0,0121637427",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"34,08","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_021,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19689,281,20073,"0,013998904",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"34,2","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_002,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20889,280,21260,"0,0131702728",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,8","15,4"
"low bq, low freq, many artifacts, many samples",UPN2_003,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4008,51,4075,"0,0125153374",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,8",14
"low bq, low freq, many artifacts, many samples",UPN2_022,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),25780,336,26240,"0,012804878",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"34,14","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_023,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),28265,383,28778,"0,0133087775",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"34,13","15,22"
"low bq, many samples",UPN2_041,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1116,27,1145,"0,023580786",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"32,59","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_024,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),12887,205,13157,"0,0155810595",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"34,2","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_025,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),30840,407,31368,"0,0129750064",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"34,15","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_026,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),30211,427,30785,"0,0138703914",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"34,25","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_004,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3521,65,3605,"0,0180305132",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,83","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_027,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),32234,440,32836,"0,0133999269",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"34,17","15,25"
"low bq, low freq, many artifacts, many samples",UPN2_042,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),32387,499,33062,"0,0150928558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,55","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_028,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22939,300,23362,"0,0128413663",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"34,23","15,25"
"low bq, low freq, many artifacts, many samples",UPN2_043,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),28010,487,28680,"0,0169804742",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,43","16,55"
"low bq, low freq, many artifacts, many samples",UPN2_044,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),7127,110,7276,"0,0151181968",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,5","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_029,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),27714,424,28260,"0,0150035386",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"34,11","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_030,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),27381,385,27940,"0,0137795276",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"34,21","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_031,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18177,273,18547,"0,0147193616",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"34,14","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_005,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),6923,107,7060,"0,0151558074",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,5","14,2"
"low bq, low freq, many artifacts, many samples",UPN2_045,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),39427,598,40219,"0,0148685944",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,39","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_032,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),9820,132,9983,"0,0132224782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"34,12","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_046,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),36854,591,37628,"0,0157063889",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,53","15,66"
"low bq, low freq, many artifacts, many samples",UPN2_033,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21203,305,21632,"0,0140994822",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"34,17","15,31"
"low bq, low freq, many artifacts, many samples",UPN2_034,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),8261,99,8393,"0,0117955439",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"34,24","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_047,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),38701,715,39606,"0,0180528203",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,4","15,46"
"low bq, low freq, many artifacts, many samples",UPN2_048,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4831,78,4924,"0,0158407799",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,39","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_035,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),23004,319,23467,"0,0135935569",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"34,13","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_036,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),23182,314,23588,"0,0133118535",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"34,2","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_006,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),7225,111,7356,"0,0150897227",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,75","16,38"
"low bq, low freq, many artifacts, many samples",UPN2_049,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17607,301,17997,"0,0167250097",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,5","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_050,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),36452,640,37279,"0,0171678425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,45","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_037,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),42682,576,43471,"0,0132502128",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"34,25","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_051,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),28312,460,28934,"0,0158982512",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,52","15,83"
"low bq, low freq, many artifacts, many samples",UPN2_052,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),32157,552,32877,"0,0167898531",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,51","15,84"
"low bq, low freq, many artifacts, many samples",UPN2_038,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),47005,619,47817,"0,0129451869",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"34,22","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_039,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21153,289,21540,"0,0134168988",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"34,24","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_053,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),41643,654,42536,"0,0153752116",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,5","15,88"
"low bq, low freq, many artifacts, many samples",UPN2_054,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),26494,436,27066,"0,0161087712",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,5","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_007,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),45956,692,46847,"0,0147714902",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,75","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_008,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),63431,898,64589,"0,0139032962",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,79","15,17"
"low bq, low freq, many artifacts, many samples",UPN2_009,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),54156,779,55198,"0,0141128302",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,79","15,37"
"low bq, low freq, many artifacts, many samples",UPN2_010,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),35532,527,36221,"0,0145495707",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,78","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_011,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),41025,723,41933,"0,0172417905",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,64","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_055,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),41430,750,42388,"0,0176936869",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,37","15,54"
"low bq, low freq, many artifacts, many samples",UPN2_056,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4171,71,4268,"0,0166354264",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,54","15,61"
"low bq, low freq, many artifacts, many samples",UPN2_057,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),34896,577,35657,"0,0161819559",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,43","15,55"
"low bq, low freq, many artifacts, many samples",UPN2_058,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),31466,534,32140,"0,0166148102",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,53","16,64"
"low bq, low freq, many artifacts, many samples",UPN2_059,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),13353,161,13578,"0,0118574164",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,13","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_012,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22602,318,23008,"0,0138212796",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,75","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_060,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20531,241,20856,"0,0115554277",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,16","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_040,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17308,291,17714,"0,0164276843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"34,19","17,82"
"low bq, low freq, many artifacts, many samples",UPN2_013,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),13592,194,13847,"0,0140102549",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,78","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_061,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20685,235,21015,"0,0111824887",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,21","15,48"
"low bq, low freq, many artifacts, many samples",UPN2_063,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18868,262,19211,"0,0136380199",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,12","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_064,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10543,109,10684,"0,0102021715",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,2","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_065,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),12644,136,12845,"0,0105877773",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,17","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_066,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18494,195,18750,"0,0104",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,14","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_067,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17073,198,17344,"0,0114160517",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,3","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_068,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),14956,152,15187,"0,01000856",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,13","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_069,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20392,235,20741,"0,0113302155",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,21","15,8"
"low bq, low freq, many artifacts, many samples",UPN2_070,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),12839,152,13038,"0,0116582298",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,15","15,66"
"low bq, low freq, many artifacts, many samples",UPN2_071,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15772,177,16031,"0,0110411079",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,15","15,46"
"low bq, low freq, many artifacts, many samples",UPN2_072,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15329,161,15555,"0,0103503697",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,22","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_073,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10890,128,11063,"0,0115700985",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,25","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_074,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10530,116,10698,"0,0108431483",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,18","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_075,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22371,268,22761,"0,0117745266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,15","15,92"
"low bq, low freq, many artifacts, many samples",UPN2_076,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19019,221,19341,"0,0114265033",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,13","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_077,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20088,231,20397,"0,0113251949",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,15","16,36"
"low bq, low freq, many artifacts, many samples",UPN2_078,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20219,205,20499,"0,0100004878",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,2","16,16"
"low bq, low freq, many artifacts, many samples",UPN2_079,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),13130,179,13379,"0,0133791763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,1","16,01"
"low bq, low freq, many artifacts, many samples",UPN2_080,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19792,238,20098,"0,0118419743",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,14","16,4"
"low bq, low freq, many artifacts, many samples",UPN2_081,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16432,185,16701,"0,011077181",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,22","15,59"
"low bq, low freq, many artifacts, many samples",UPN2_082,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19649,225,19956,"0,0112748046",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,23","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_084,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20595,228,20905,"0,0109064817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,11","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_085,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15486,204,15769,"0,0129367747",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,17","16,81"
"low bq, low freq, many artifacts, many samples",UPN2_087,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20935,281,21317,"0,0131819674",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,01","16,11"
"low bq, low freq, many artifacts",UPN2_088,20,31023028,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys838Met/c.2513A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15351,177,15618,"0,0113330772",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,0,Damaging,"33,22","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_001,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15991,342,16356,"0,0209097579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"33,74","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_014,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),25700,456,26206,"0,0174005953",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"33,67","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_015,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),33966,629,34654,"0,0181508628",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"33,75","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_016,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17212,306,17542,"0,017443849",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"33,66","14,11"
"low bq, low freq, many artifacts, many samples",UPN2_017,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),11611,190,11822,"0,0160717307",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"33,78","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_018,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17289,314,17653,"0,0177873449",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"33,64","14,15"
"low bq, low freq, many artifacts, many samples",UPN2_019,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19066,328,19416,"0,0168932839",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"33,67","14,06"
"low bq, low freq, many artifacts, many samples",UPN2_020,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16772,297,17096,"0,0173724848",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"33,67","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_021,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19688,345,20066,"0,0171932622",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"33,65","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_002,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20768,452,21247,"0,0212735916",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"33,68","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_003,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3991,76,4072,"0,0186640472",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"33,74","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_022,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),25673,495,26220,"0,0188787185",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"33,7","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_023,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),28185,535,28761,"0,0186015785",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"33,61","14,19"
"low bq, many samples",UPN2_041,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1097,42,1144,"0,0367132867",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"31,86","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_024,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),12873,228,13152,"0,0173357664",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"33,75","14,11"
"low bq, low freq, many artifacts, many samples",UPN2_025,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),30745,559,31342,"0,0178354923",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"33,61","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_026,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),30188,522,30759,"0,0169706427",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"33,72","14,3"
"low bq, many samples",UPN2_004,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3504,90,3603,"0,024979184",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"33,65","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_027,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),32168,592,32817,"0,0180394308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"33,72","14,4"
"low bq, many samples",UPN2_042,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),32084,910,33052,"0,0275323732",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,95","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_028,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22900,412,23349,"0,0176452953",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"33,67","14,07"
"low bq, many samples",UPN2_043,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),27780,784,28668,"0,0273475652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,96","14,43"
"low bq, many samples",UPN2_044,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),7061,201,7272,"0,027640264",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,98","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_029,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),27656,527,28252,"0,0186535467",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"33,7","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_030,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),27338,534,27923,"0,0191240196",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"33,71","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_031,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18140,369,18535,"0,0199082816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"33,66","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_005,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),6901,141,7054,"0,0199886589",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"33,53","14,23"
"low bq, many samples",UPN2_045,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),39026,1058,40201,"0,0263177533",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,92","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_032,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),9769,188,9981,"0,018835788",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"33,61","14,53"
"low bq, many samples",UPN2_046,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),36572,954,37613,"0,0253635711",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,95","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_033,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21144,426,21623,"0,019701244",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"33,62","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_034,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),8242,138,8388,"0,0164520744",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"33,75","14,18"
"low bq, many samples",UPN2_047,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),38522,966,39591,"0,0243994847",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,84","14,42"
"low bq, many samples",UPN2_048,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4771,143,4921,"0,0290591343",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,9","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_035,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22962,439,23457,"0,0187150957",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"33,63","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_036,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),23102,451,23584,"0,0191231343",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"33,64","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_006,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),7199,146,7353,"0,0198558412",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"33,67","14,59"
"low bq, many samples",UPN2_049,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17475,469,17992,"0,026067141",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,89","14,32"
"low bq, many samples",UPN2_050,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),36148,1036,37260,"0,0278046162",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,9","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_037,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),42609,769,43439,"0,0177029858",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"33,72","14,11"
"low bq, many samples",UPN2_051,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),28073,781,28920,"0,0270055325",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,95","15,05"
"low bq, many samples",UPN2_052,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),31865,893,32864,"0,0271725901",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,95","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_038,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),46808,909,47791,"0,0190203176",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"33,74","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_039,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21078,406,21527,"0,0188600362",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"33,75","14,28"
"low bq, many samples",UPN2_053,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),41279,1125,42509,"0,0264649839",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,87","14,57"
"low bq, many samples",UPN2_054,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),26287,710,27051,"0,0262467192",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,98","14,7"
"low bq, many samples",UPN2_007,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),45645,1059,46801,"0,0226277216",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"33,63","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_008,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),63099,1340,64541,"0,0207619963",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"33,66","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_009,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),53840,1198,55151,"0,0217221809",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"33,65","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_010,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),35409,733,36197,"0,020250297",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"33,62","14,21"
"low bq, many samples",UPN2_011,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),40874,958,41902,"0,0228628705",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"33,63","15,34"
"low bq, many samples",UPN2_055,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),41162,1115,42376,"0,0263120634",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,96","14,46"
"low bq, many samples",UPN2_056,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4139,114,4266,"0,0267229255",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,95","14,18"
"low bq, many samples",UPN2_057,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),34568,995,35646,"0,0279133704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,91","15,15"
"low bq, many samples",UPN2_058,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),31214,860,32130,"0,0267662621",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"33,04","14,58"
"low bq, many samples",UPN2_059,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),13208,324,13572,"0,023872679",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,43","14,6"
"low bq, many samples",UPN2_012,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22466,508,22994,"0,0220927198",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"33,62","14,24"
"low bq, many samples",UPN2_060,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20300,502,20851,"0,0240755839",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,52","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_040,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17372,312,17706,"0,0176211454",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"33,74","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_013,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),13513,300,13836,"0,0216825672",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"33,69","14,22"
"low bq, many samples",UPN2_061,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20454,499,21008,"0,0237528561",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,57","14,83"
"low bq, many samples",UPN2_062,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19406,456,19912,"0,0229007634",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,57","14,59"
"low bq, many samples",UPN2_063,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18722,436,19208,"0,0226988755",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,51","14,88"
"low bq, many samples",UPN2_064,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10384,266,10681,"0,0249040352",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,58","14,95"
"low bq, many samples",UPN2_065,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),12504,304,12842,"0,0236723252",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,48",15
"low bq, many samples",UPN2_066,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18233,452,18749,"0,0241079524",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,43","14,7"
"low bq, many samples",UPN2_067,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16831,457,17343,"0,026350689",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,52","15,19"
"low bq, many samples",UPN2_068,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),14793,352,15185,"0,0231807705",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,57","14,92"
"low bq, many samples",UPN2_069,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20182,480,20737,"0,0231470319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,55","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_070,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),12735,276,13035,"0,0211737629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,52","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_071,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15641,343,16030,"0,0213973799",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,6","14,92"
"low bq, many samples",UPN2_072,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15170,356,15554,"0,0228880031",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,6","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_073,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10791,241,11060,"0,0217902351",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,61","14,71"
"low bq, many samples",UPN2_074,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10408,261,10696,"0,0244016455",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,51","15,13"
"low bq, many samples",UPN2_075,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22168,540,22754,"0,0237320911",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,47","14,89"
"low bq, many samples",UPN2_076,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18796,495,19337,"0,0255985934",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,49","15,26"
"low bq, many samples",UPN2_077,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19834,517,20393,"0,0253518364",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,49","14,82"
"low bq, many samples",UPN2_078,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19966,479,20494,"0,0233726944",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,54","14,83"
"low bq, many samples",UPN2_079,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),13047,303,13378,"0,0226491254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,52","14,86"
"low bq, many samples",UPN2_080,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19581,458,20096,"0,0227906051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,5","15,15"
"low bq, many samples",UPN2_081,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16208,430,16698,"0,025751587",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,54","14,99"
"low bq, many samples",UPN2_082,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19434,461,19953,"0,0231042951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,61","15,14"
"low bq, many samples",UPN2_083,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22044,516,22599,"0,0228328687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,57",15
"low bq, many samples",UPN2_084,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20357,485,20904,"0,0232013012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,5","14,89"
"low bq, many samples",UPN2_085,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15313,402,15765,"0,0254995243",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,47","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_086,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10637,238,10900,"0,0218348624",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,48","15,22"
"low bq, many samples",UPN2_087,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20772,486,21315,"0,0228008445",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,46","14,76"
low bq,UPN2_088,20,31023029,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys838Asn/c.2514G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15194,366,15614,"0,0234405021",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"3,30E-005",NO,NO,"-1,43",Neutral,1,Damaging,"32,43","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_001,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16053,276,16347,"0,0168838319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"33,47",14
"low bq, low freq, many artifacts, many samples",UPN2_014,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),25726,428,26190,"0,0163421153",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"33,09","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_015,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),34023,567,34639,"0,0163688328",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"33,2","14,13"
"low bq, low freq, many artifacts, many samples",UPN2_016,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17238,277,17532,"0,0157996806",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"33,09","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_017,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),11633,171,11817,"0,0144706778",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"33,2",14
"low bq, low freq, many artifacts, many samples",UPN2_018,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17325,292,17641,"0,0165523496",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"33,05","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_019,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19088,308,19415,"0,0158640227",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"33,14","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_020,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16840,234,17085,"0,0136962248",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"33,11","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_021,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19693,316,20061,"0,0157519565",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"33,13","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_002,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20838,372,21240,"0,0175141243",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"33,5","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_003,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3998,71,4073,"0,0174318684",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"33,45",14
"low bq, low freq, many artifacts, many samples",UPN2_022,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),25726,427,26204,"0,0162952221",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"33,13","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_023,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),28190,498,28743,"0,0173259576",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"33,07","14,42"
"low bq, many samples",UPN2_041,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1103,40,1145,"0,0349344978",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"31,49","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_024,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),12913,205,13139,"0,0156024051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"33,16","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_025,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),30777,516,31331,"0,0164693115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"33,02","14,12"
"low bq, low freq, many artifacts, many samples",UPN2_026,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),30213,474,30740,"0,0154196487",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"33,12","14,35"
"low bq, many samples",UPN2_004,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3515,83,3600,"0,0230555556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"33,59","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_027,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),32198,551,32789,"0,0168044161",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"33,13","14,78"
"low bq, many samples",UPN2_042,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),32145,835,33044,"0,0252693379",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,45","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_028,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22915,399,23337,"0,0170973133",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"33,13","14,45"
"low bq, many samples",UPN2_043,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),27867,719,28645,"0,0251003666",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,4","14,37"
"low bq, many samples",UPN2_044,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),7060,197,7269,"0,0271013895",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,66","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_029,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),27697,482,28234,"0,0170716158",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"33,09","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_030,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),27390,471,27906,"0,0168780907",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"33,13","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_031,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18170,337,18527,"0,0181896691",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"33,07","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_005,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),6898,137,7051,"0,0194298681",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"33,17","14,18"
"low bq, many samples",UPN2_045,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),39098,992,40171,"0,0246944313",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,4","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_032,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),9798,157,9971,"0,0157456624",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"33,07","14,82"
"low bq, many samples",UPN2_046,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),36567,936,37586,"0,0249028894",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,5","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_033,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21212,362,21611,"0,0167507288",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"33,06","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_034,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),8239,145,8388,"0,0172865999",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"33,23","15,59"
"low bq, many samples",UPN2_047,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),38511,981,39566,"0,0247940151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,37","14,25"
"low bq, many samples",UPN2_048,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4787,123,4919,"0,0250050823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,32","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_035,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),23010,396,23440,"0,016894198",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"33,04","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_036,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),23158,383,23575,"0,0162460233",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"33,08","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_006,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),7209,126,7348,"0,0171475231",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"33,51","14,51"
"low bq, many samples",UPN2_049,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17499,454,17984,"0,0252446619",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,38","14,2"
"low bq, many samples",UPN2_050,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),36123,1050,37244,"0,0281924605",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,38","15,31"
"low bq, low freq, many artifacts, many samples",UPN2_037,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),42663,694,43413,"0,015985995",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"33,18","14,15"
"low bq, many samples",UPN2_051,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),28097,755,28907,"0,0261182413",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,45","14,92"
"low bq, many samples",UPN2_052,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),31986,790,32840,"0,0240560292",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,42","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_038,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),46953,744,47765,"0,0155762588",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"33,14","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_039,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21114,360,21513,"0,0167340678",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"33,14","14,4"
"low bq, many samples",UPN2_053,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),41322,1071,42477,"0,025213645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,38","15,15"
"low bq, many samples",UPN2_054,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),26253,734,27035,"0,0271499908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,52","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_007,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),45780,939,46780,"0,0200726806",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"33,43","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_008,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),63234,1196,64505,"0,0185411984",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"33,49","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_009,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),53979,1049,55112,"0,0190339672",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"33,47","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_010,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),35414,709,36180,"0,0195964621",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"33,46","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_011,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),40973,848,41873,"0,0202517135",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"33,34","15,31"
"low bq, many samples",UPN2_055,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),41212,1039,42343,"0,024537704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,36","14,67"
"low bq, many samples",UPN2_056,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4152,107,4264,"0,0250938086",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,28","14,94"
"low bq, many samples",UPN2_057,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),34591,932,35626,"0,0261606692",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,44","14,22"
"low bq, many samples",UPN2_058,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),31234,791,32105,"0,0246379069",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,46","14,39"
"low bq, many samples",UPN2_059,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),13187,346,13570,"0,0254974208",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,12","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_012,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22501,459,22990,"0,0199652023",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"33,42","14,56"
"low bq, many samples",UPN2_060,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20274,510,20844,"0,0244674727",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,11","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_040,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17401,273,17698,"0,0154254718",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"33,08","14,03"
"low bq, low freq, many artifacts, many samples",UPN2_013,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),13520,285,13830,"0,0206073753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"33,39","14,07"
"low bq, many samples",UPN2_061,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20408,513,21000,"0,0244285714",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,21","14,44"
"low bq, many samples",UPN2_062,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19385,459,19907,"0,0230572161",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,25","14,71"
"low bq, many samples",UPN2_063,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18701,436,19206,"0,0227012392",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,07","14,82"
"low bq, many samples",UPN2_064,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10380,263,10674,"0,0246393105",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,23","14,66"
"low bq, many samples",UPN2_065,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),12457,347,12839,"0,027027027",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,28","14,79"
"low bq, many samples",UPN2_066,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18218,460,18733,"0,0245555971",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,13","14,68"
"low bq, many samples",UPN2_067,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16854,428,17341,"0,0246813909",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,09","15,11"
"low bq, many samples",UPN2_068,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),14763,345,15183,"0,0227227821",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,2","14,67"
"low bq, many samples",UPN2_069,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20173,492,20725,"0,0237394451",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,24","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_070,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),12712,279,13029,"0,0214137693",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,1","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_071,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15647,332,16022,"0,0207215079",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,15","14,88"
"low bq, many samples",UPN2_072,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15097,391,15547,"0,0251495465",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,39","15,16"
"low bq, many samples",UPN2_073,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10762,263,11058,"0,023783686",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,21","15,06"
"low bq, many samples",UPN2_074,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10387,272,10692,"0,025439581",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,19","14,61"
"low bq, many samples",UPN2_075,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22112,558,22748,"0,024529629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,14","15,13"
"low bq, many samples",UPN2_076,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18758,510,19332,"0,0263811297",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,16","14,74"
"low bq, many samples",UPN2_077,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19805,521,20390,"0,025551741",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,16","14,4"
"low bq, many samples",UPN2_078,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19957,470,20489,"0,0229391381",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,21","15,07"
"low bq, many samples",UPN2_079,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),13004,322,13372,"0,0240801675",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,17",15
"low bq, many samples",UPN2_080,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19531,502,20090,"0,024987556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,11","14,89"
"low bq, many samples",UPN2_081,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16227,394,16690,"0,0236069503",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,11","14,99"
"low bq, many samples",UPN2_082,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19427,468,19948,"0,0234609986",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,27","14,98"
"low bq, many samples",UPN2_083,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21994,537,22596,"0,0237652682",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,25","14,75"
"low bq, many samples",UPN2_084,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20274,557,20896,"0,0266558193",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,26","14,53"
"low bq, many samples",UPN2_085,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15306,396,15764,"0,0251205278",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,06","14,62"
"low bq, many samples",UPN2_086,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10604,255,10898,"0,0233987888",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,13","15,06"
"low bq, many samples",UPN2_087,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20682,545,21308,"0,025577248",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,08","14,67"
low bq,UPN2_088,20,31023030,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp839Tyr/c.2515G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15187,370,15605,"0,0237103492",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,82",Neutral,0,Damaging,"32,12","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_001,20,31023031,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp839Val/c.2516A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16121,204,16386,"0,0124496521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"33,52","16,05"
"low bq, low freq, many artifacts, many samples",UPN2_002,20,31023031,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp839Val/c.2516A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21007,252,21311,"0,0118248792",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"33,43","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_003,20,31023031,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp839Val/c.2516A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4033,51,4089,"0,0124724872",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"33,54","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_041,20,31023031,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp839Val/c.2516A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1124,25,1154,"0,0216637782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,25","15,92"
"low bq, low freq, many artifacts, many samples",UPN2_004,20,31023031,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp839Val/c.2516A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3534,59,3610,"0,0163434903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"33,45","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_042,20,31023031,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp839Val/c.2516A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),32624,447,33176,"0,0134735954",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,94","16,32"
"low bq, low freq, many artifacts, many samples",UPN2_043,20,31023031,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp839Val/c.2516A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),28276,392,28768,"0,0136262514",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,93","16,84"
"low bq, low freq, many artifacts, many samples",UPN2_044,20,31023031,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp839Val/c.2516A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),7194,82,7296,"0,0112390351",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,91","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_005,20,31023031,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp839Val/c.2516A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),6962,95,7073,"0,0134313587",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"33,31","17,06"
"low bq, low freq, many artifacts, many samples",UPN2_045,20,31023031,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp839Val/c.2516A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),39707,502,40346,"0,0124423735",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,83","15,59"
"low bq, low freq, many artifacts, many samples",UPN2_046,20,31023031,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp839Val/c.2516A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),37119,500,37772,"0,0132373186",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,94","16,9"
"low bq, low freq, many artifacts, many samples",UPN2_047,20,31023031,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp839Val/c.2516A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),38988,639,39747,"0,016076685",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,82","16,75"
"low bq, low freq, many artifacts, many samples",UPN2_048,20,31023031,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp839Val/c.2516A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4844,80,4935,"0,0162107396",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,92","16,31"
"low bq, low freq, many artifacts, many samples",UPN2_006,20,31023031,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp839Val/c.2516A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),7263,94,7377,"0,0127423072",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"33,49","15,4"
"low bq, low freq, many artifacts, many samples",UPN2_049,20,31023031,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp839Val/c.2516A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17768,226,18065,"0,0125103792",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,86","15,57"
"low bq, low freq, many artifacts, many samples",UPN2_050,20,31023031,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp839Val/c.2516A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),36763,479,37364,"0,0128198266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,9","15,68"
"low bq, low freq, many artifacts, many samples",UPN2_051,20,31023031,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp839Val/c.2516A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),28559,372,29019,"0,0128191874",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,99","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_052,20,31023031,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp839Val/c.2516A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),32454,391,32979,"0,0118560296",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,86","16,06"
"low bq, low freq, many artifacts, many samples",UPN2_053,20,31023031,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp839Val/c.2516A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),41967,536,42657,"0,0125653468",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,9","16,49"
"low bq, low freq, many artifacts, many samples",UPN2_054,20,31023031,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp839Val/c.2516A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),26748,323,27150,"0,0118968692",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,88","16,03"
"low bq, low freq, many artifacts, many samples",UPN2_007,20,31023031,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp839Val/c.2516A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),46194,573,46933,"0,0122088935",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"33,37","15,69"
"low bq, low freq, many artifacts, many samples",UPN2_008,20,31023031,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp839Val/c.2516A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),63712,777,64714,"0,0120066755",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"33,41","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_009,20,31023031,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp839Val/c.2516A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),54450,683,55300,"0,0123508137",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"33,41","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_010,20,31023031,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp839Val/c.2516A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),35759,429,36305,"0,0118165542",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"33,37","16,03"
"low bq, low freq, many artifacts, many samples",UPN2_011,20,31023031,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp839Val/c.2516A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),41319,607,42035,"0,0144403473",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"33,23","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_055,20,31023031,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp839Val/c.2516A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),41813,558,42515,"0,0131247795",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,81","15,34"
"low bq, low freq, many artifacts, many samples",UPN2_056,20,31023031,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp839Val/c.2516A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4219,51,4274,"0,0119326158",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"33,04","15,55"
"low bq, low freq, many artifacts, many samples",UPN2_057,20,31023031,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp839Val/c.2516A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),35237,399,35771,"0,011154287",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,89","15,48"
"low bq, low freq, many artifacts, many samples",UPN2_058,20,31023031,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp839Val/c.2516A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),31779,360,32242,"0,0111655604",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"32,98","15,65"
"low bq, low freq, many artifacts, many samples",UPN2_012,20,31023031,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp839Val/c.2516A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22710,282,23051,"0,0122337426",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"33,43","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_013,20,31023031,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp839Val/c.2516A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),13672,177,13882,"0,0127503242",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"33,31","16,34"
"low bq, low freq, many artifacts, many samples",UPN2_085,20,31023031,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp839Val/c.2516A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15580,167,15820,"0,0105562579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"31,95","15,7"
"low bq, low freq, many artifacts",UPN2_087,20,31023031,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp839Val/c.2516A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21003,226,21354,"0,0105834972",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,1,Damaging,"31,9","15,32"
"low bq, many samples",UPN2_001,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),15918,409,16389,"0,024955763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"32,53","18,13"
"low bq, low freq, many artifacts, many samples",UPN2_014,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),25617,519,26312,"0,0197248404",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,82","18,32"
"low bq, low freq, many artifacts, many samples",UPN2_015,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),33824,759,34813,"0,0218022003",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,92","18,43"
"low bq, low freq, many artifacts, many samples",UPN2_016,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),17148,361,17608,"0,0205020445",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,76","17,81"
"low bq, low freq, many artifacts, many samples",UPN2_017,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),11582,209,11866,"0,0176133491",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,87","17,55"
"low bq, low freq, many artifacts, many samples",UPN2_018,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),17215,383,17703,"0,0216347512",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,79","18,18"
"low bq, low freq, many artifacts, many samples",UPN2_019,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),18981,393,19478,"0,0201766095",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,85","17,48"
"low bq, low freq, many artifacts, many samples",UPN2_020,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),16744,318,17174,"0,0185163619",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,77","18,3"
"low bq, low freq, many artifacts, many samples",UPN2_021,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),19601,406,20141,"0,0201578869",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,76","17,59"
"low bq, many samples",UPN2_002,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),20671,499,21316,"0,0234096453",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"32,58","18,22"
"low bq, low freq, many artifacts, many samples",UPN2_003,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),3982,88,4090,"0,0215158924",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"32,46","17,68"
"low bq, low freq, many artifacts, many samples",UPN2_022,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),25603,551,26330,"0,0209266996",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,79","18,44"
"low bq, low freq, many artifacts, many samples",UPN2_023,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),28075,622,28863,"0,0215500814",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,77","18,29"
"low bq, many samples",UPN2_041,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),1100,42,1155,"0,0363636364",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"30,89","19,14"
"low bq, low freq, many artifacts, many samples",UPN2_024,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),12852,256,13209,"0,0193807253",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,86","18,23"
"low bq, low freq, many artifacts, many samples",UPN2_025,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),30617,664,31466,"0,021102142",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,74","18,53"
"low bq, low freq, many artifacts, many samples",UPN2_026,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),30055,614,30889,"0,0198776263",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,86","18,28"
"low bq, low freq, many artifacts, many samples",UPN2_027,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),32026,710,32962,"0,0215399551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,79","18,34"
"low bq, many samples",UPN2_089,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),19800,567,20517,"0,0276356192",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,39","18,72"
"low bq, many samples",UPN2_042,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),32067,891,33181,"0,0268527169",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,22","17,85"
"low bq, low freq, many artifacts, many samples",UPN2_028,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),22806,498,23450,"0,0212366738",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,88","18,34"
"low bq, many samples, no database",UPN2_043,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),27767,778,28769,"0,0270429977",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,"0,018",Damaging,"31,22","18,12"
"low bq, many samples",UPN2_044,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),7053,202,7297,"0,0276826093",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,28","17,64"
"low bq, low freq, many artifacts, many samples",UPN2_029,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),27582,611,28357,"0,021546708",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,73","18,84"
"low bq, low freq, many artifacts, many samples",UPN2_031,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),18097,400,18612,"0,0214915109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,78","18,6"
"low bq, many samples",UPN2_005,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),6848,197,7075,"0,027844523",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"32,27","17,7"
"low bq, many samples",UPN2_045,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),39002,1075,40350,"0,0266418835",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,27","17,88"
"low bq, low freq, many artifacts, many samples",UPN2_032,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),9756,205,10011,"0,0204774748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,76","18,67"
"low bq, many samples",UPN2_046,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),36492,964,37774,"0,0255201991",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,3","18,03"
"low bq, low freq, many artifacts, many samples",UPN2_033,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),21107,475,21722,"0,0218672314",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,74","18,13"
"low bq, low freq, many artifacts, many samples",UPN2_034,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),8216,161,8425,"0,0191097923",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,91","18,44"
"low bq, many samples",UPN2_047,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),38439,1027,39748,"0,025837778",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,11","18,15"
"low bq, many samples",UPN2_048,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),4760,142,4935,"0,0287740628",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,24","18,22"
"low bq, low freq, many artifacts, many samples",UPN2_035,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),22918,489,23551,"0,0207634495",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,69","18,27"
"low bq, low freq, many artifacts, many samples",UPN2_036,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),23005,510,23683,"0,021534434",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,79","18,61"
"low bq, many samples",UPN2_006,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),7165,175,7376,"0,0237255965",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"32,52","17,81"
"low bq, many samples",UPN2_049,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),17427,483,18069,"0,026730865",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,14","17,67"
"low bq, many samples, no database",UPN2_050,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),36082,1038,37371,"0,0277755479",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,"0,018",Damaging,"31,17","18,27"
"low bq, low freq, many artifacts, many samples",UPN2_037,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),42431,908,43595,"0,0208280766",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,9","18,25"
"low bq, many samples",UPN2_051,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),28057,756,29022,"0,0260492041",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,21","17,37"
"low bq, many samples",UPN2_052,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),31900,865,32985,"0,0262240412",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,27","18,18"
"low bq, low freq, many artifacts, many samples",UPN2_038,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),46657,1026,47977,"0,0213852471",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,83","18,54"
"low bq, low freq, many artifacts, many samples",UPN2_039,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),21009,444,21600,"0,0205555556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,84","19,11"
"low bq, many samples",UPN2_053,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),41268,1075,42663,"0,0251974779",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,13","17,65"
"low bq, many samples",UPN2_054,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),26270,716,27147,"0,0263749217",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,27","18,03"
"low bq, many samples, no database",UPN2_007,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),45346,1264,46937,"0,0269297143",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,"0,018",Damaging,"32,47","19,01"
"low bq, many samples",UPN2_008,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),62701,1645,64726,"0,0254148256",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"32,51","17,96"
"low bq, many samples",UPN2_009,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),53537,1476,55309,"0,0266864344",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"32,5","18,08"
"low bq, many samples",UPN2_010,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),35195,922,36314,"0,0253896569",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"32,54","17,93"
"low bq, many samples",UPN2_011,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),40606,1128,42043,"0,0268296744",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"32,47","18,16"
"low bq, many samples",UPN2_055,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),41082,1133,42522,"0,0266450308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,12","18,11"
"low bq, many samples",UPN2_056,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),4133,118,4276,"0,027595884",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,33","17,6"
"low bq, many samples, no database",UPN2_057,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),34517,1006,35775,"0,0281201957",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,"0,018",Damaging,"31,15","18,14"
"low bq, many samples, no database",UPN2_058,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),31179,853,32248,"0,0264512528",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,"0,018",Damaging,"31,24","18,54"
"low bq, many samples",UPN2_059,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),13207,322,13615,"0,0236503856",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,13","18,03"
"low bq, many samples",UPN2_012,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),22322,629,23060,"0,0272766696",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"32,45","17,87"
"low bq, low freq, many artifacts, many samples",UPN2_060,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),20332,455,20912,"0,0217578424",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,14","17,29"
"low bq, low freq, many artifacts, many samples",UPN2_040,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),17299,362,17774,"0,020366828",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,83","18,02"
"low bq, many samples",UPN2_092,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),10897,295,11290,"0,026129318",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,26","18,51"
"low bq, many samples",UPN2_093,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),11884,373,12355,"0,0301902064",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,41","18,13"
"low bq, many samples",UPN2_061,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),20447,465,21071,"0,0220682455",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,22","18,35"
"low bq, low freq, many artifacts, many samples",UPN2_062,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),19421,430,19984,"0,0215172138",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,31","17,83"
"low bq, many samples",UPN2_063,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),18727,425,19256,"0,0220710428",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,13","17,41"
"low bq, many samples",UPN2_064,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),10381,267,10703,"0,0249462767",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,26","17,31"
"low bq, many samples",UPN2_065,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),12518,293,12870,"0,0227661228",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,13","17,49"
"low bq, many samples",UPN2_066,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),18259,414,18794,"0,0220283069",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,1","17,19"
"low bq, many samples",UPN2_067,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),16865,423,17404,"0,0243047575",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,16","16,67"
"low bq, many samples",UPN2_068,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),14785,349,15235,"0,0229077781",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,23","18,09"
"low bq, low freq, many artifacts, many samples",UPN2_069,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),20209,451,20792,"0,021691035",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,18","17,2"
"low bq, low freq, many artifacts, many samples",UPN2_070,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),12723,262,13070,"0,0200459067",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,25","17,31"
"low bq, low freq, many artifacts, many samples",UPN2_071,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),15641,329,16061,"0,0204844032",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,29","17,85"
"low bq, many samples",UPN2_072,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),15153,357,15599,"0,0228860824",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,3","18,89"
"low bq, many samples",UPN2_073,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),10784,250,11098,"0,0225265814",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,14","16,7"
"low bq, many samples",UPN2_074,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),10408,251,10719,"0,0234163635",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,15","18,15"
"low bq, many samples",UPN2_075,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),22160,515,22798,"0,0225897009",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,15","17,19"
"low bq, many samples",UPN2_076,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),18844,446,19400,"0,0229896907",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,23","16,69"
"low bq, many samples",UPN2_077,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),19804,518,20450,"0,0253300733",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,23","16,96"
"low bq, low freq, many artifacts, many samples",UPN2_078,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),19992,445,20559,"0,0216450216",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,22","17,46"
"low bq, many samples",UPN2_079,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),13021,308,13424,"0,0229439809",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,2","17,44"
"low bq, many samples",UPN2_080,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),19575,469,20147,"0,0232789001",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,18","17,11"
"low bq, many samples",UPN2_081,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),16264,384,16738,"0,0229418091",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,15","17,88"
"low bq, low freq, many artifacts, many samples",UPN2_082,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),19458,437,20005,"0,0218445389",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,17","17,36"
"low bq, low freq, many artifacts, many samples",UPN2_083,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),22062,468,22666,"0,0206476661",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,24","17,17"
"low bq, many samples",UPN2_084,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),20337,500,20953,"0,0238629313",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,21","17,93"
"low bq, many samples",UPN2_085,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),15326,396,15818,"0,0250347705",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,31,"17,22"
"low bq, low freq, many artifacts, many samples",UPN2_086,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),10617,240,10926,"0,0219659528",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,25","17,43"
"low bq, many samples",UPN2_087,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),20755,499,21356,"0,0233657988",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,13","17,19"
"low bq, many samples",UPN2_088,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),15205,351,15657,"0,0224180878",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,11","17,29"
"low bq, many samples",UPN2_097,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),23737,698,24608,"0,0283647594",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,4","18,87"
"low bq, many samples",UPN2_098,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),17291,499,17938,"0,0278180399",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,31","18,18"
"low bq, many samples",UPN2_100,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),16792,481,17409,"0,0276293871",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,34","18,48"
"low bq, many samples",UPN2_101,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),17672,472,18279,"0,0258219815",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,34","18,57"
"low bq, many samples",UPN2_107,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),31419,882,32595,"0,0270593649",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,41","18,77"
"low bq, many samples",UPN2_108,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),26484,721,27433,"0,0262822149",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,41","18,57"
"low bq, many samples",UPN2_110,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),29451,839,30553,"0,0274604785",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,52","18,51"
low bq,UPN2_111,20,31023033,C,A,missense_variant(MODERATE|MISSENSE|Cct/Act|p.Pro840Thr/c.2518C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),22436,598,23217,"0,0257569884",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,25",Neutral,18,Damaging,"31,38","18,51"
"low bq, low freq, many artifacts, many samples",UPN2_043,20,31023034,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro840His/c.2519C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),27650,322,28649,"0,0112394848",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,23",Neutral,3,Damaging,"31,25","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_045,20,31023034,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro840His/c.2519C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),38820,422,40184,"0,0105016922",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,23",Neutral,3,Damaging,"31,18","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_046,20,31023034,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro840His/c.2519C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),36334,404,37595,"0,0107461099",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,23",Neutral,3,Damaging,"31,21","16,33"
"low bq, low freq, many artifacts, many samples",UPN2_047,20,31023034,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro840His/c.2519C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),38276,409,39584,"0,0103324576",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,23",Neutral,3,Damaging,"31,15","15,6"
"low bq, low freq, many artifacts, many samples",UPN2_048,20,31023034,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro840His/c.2519C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),4754,55,4921,"0,0111765901",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,23",Neutral,3,Damaging,"31,13","15,65"
"low bq, low freq, many artifacts, many samples",UPN2_049,20,31023034,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro840His/c.2519C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),17350,199,17996,"0,0110580129",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,23",Neutral,3,Damaging,"31,22","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_051,20,31023034,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro840His/c.2519C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),27955,323,28910,"0,0111726046",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,23",Neutral,3,Damaging,"31,18","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_052,20,31023034,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro840His/c.2519C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),31752,333,32859,"0,0101342098",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,23",Neutral,3,Damaging,"31,25","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_053,20,31023034,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro840His/c.2519C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),41137,431,42495,"0,0101423697",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,23",Neutral,3,Damaging,"31,1","15,39"
"low bq, low freq, many artifacts, many samples",UPN2_054,20,31023034,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro840His/c.2519C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),26098,314,27035,"0,0116145737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,23",Neutral,3,Damaging,"31,29","15,76"
"low bq, low freq, many artifacts, many samples",UPN2_055,20,31023034,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro840His/c.2519C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),40938,443,42356,"0,0104589669",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,23",Neutral,3,Damaging,"31,2","16,12"
"low bq, low freq, many artifacts, many samples",UPN2_056,20,31023034,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro840His/c.2519C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),4134,44,4268,"0,0103092784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,23",Neutral,3,Damaging,"31,22","16,05"
"low bq, low freq, many artifacts, many samples",UPN2_057,20,31023034,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro840His/c.2519C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),34412,370,35639,"0,010381885",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,23",Neutral,3,Damaging,"31,16","14,76"
"low bq, low freq, many artifacts",UPN2_058,20,31023034,C,A,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro840His/c.2519C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),31045,353,32129,"0,0109869588",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,23",Neutral,3,Damaging,"31,15","16,78"
"low bq, low freq, many artifacts, many samples",UPN2_001,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15900,326,16352,"0,0199363992",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"32,08","18,05"
"low bq, low freq, many artifacts, many samples",UPN2_014,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),25572,465,26206,"0,0177440281",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"31,06","17,94"
"low bq, low freq, many artifacts, many samples",UPN2_015,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),33758,691,34661,"0,0199359511",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"31,21","18,36"
"low bq, low freq, many artifacts, many samples",UPN2_016,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17108,312,17542,"0,0177858853",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"31,01","17,75"
"low bq, low freq, many artifacts, many samples",UPN2_017,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),11549,202,11820,"0,0170896785",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"31,15","19,44"
"low bq, low freq, many artifacts, many samples",UPN2_018,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17207,329,17650,"0,0186402266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"31,08","17,69"
"low bq, low freq, many artifacts, many samples",UPN2_019,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18948,358,19423,"0,0184317562",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"31,18","17,92"
"low bq, low freq, many artifacts, many samples",UPN2_020,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16709,268,17097,"0,0156752647",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"31,08","17,72"
"low bq, low freq, many artifacts, many samples",UPN2_021,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19584,360,20063,"0,017943478",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"31,1","17,77"
"low bq, many samples",UPN2_003,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3954,93,4075,"0,0228220859",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"32,02","17,92"
"low bq, low freq, many artifacts, many samples",UPN2_022,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),25534,487,26213,"0,0185785679",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"31,11","17,41"
"low bq, low freq, many artifacts, many samples",UPN2_023,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),28010,563,28761,"0,0195751191",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"31,08","17,45"
"low bq, many samples",UPN2_041,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1101,27,1145,"0,023580786",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"30,44","19,85"
"low bq, low freq, many artifacts, many samples",UPN2_024,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),12843,219,13149,"0,016655259",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"31,14","17,22"
"low bq, low freq, many artifacts, many samples",UPN2_025,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),30552,586,31339,"0,018698746",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,31,"17,61"
"low bq, low freq, many artifacts, many samples",UPN2_026,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),30001,584,30761,"0,0189850785",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"31,2","18,1"
"low bq, many samples",UPN2_042,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),31937,742,33053,"0,0224487944",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"31,26","18,86"
"low bq, low freq, many artifacts, many samples",UPN2_028,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22773,447,23347,"0,0191459288",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"31,15","17,89"
"low bq, many samples",UPN2_044,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),7021,170,7270,"0,0233837689",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"31,21","19,12"
"low bq, low freq, many artifacts, many samples",UPN2_029,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),27530,549,28250,"0,0194336283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"31,02","17,91"
"low bq, low freq, many artifacts, many samples",UPN2_031,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18061,343,18531,"0,0185095246",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"31,06","17,46"
"low bq, many samples",UPN2_005,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),6835,160,7054,"0,0226821661",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"31,68","17,38"
"low bq, low freq, many artifacts, many samples",UPN2_032,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),9744,176,9979,"0,0176370378",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"31,1","17,9"
"low bq, low freq, many artifacts, many samples",UPN2_033,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21047,413,21620,"0,0191026827",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"31,03","17,37"
"low bq, low freq, many artifacts, many samples",UPN2_034,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),8197,138,8394,"0,0164403145",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"31,19","18,3"
"low bq, low freq, many artifacts, many samples",UPN2_035,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22831,448,23459,"0,0190971482",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"31,09","17,78"
"low bq, low freq, many artifacts, many samples",UPN2_036,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22994,426,23585,"0,0180623278",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"31,06","17,73"
"low bq, low freq, many artifacts, many samples",UPN2_037,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),42368,793,43428,"0,0182601087",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"31,18","17,72"
"low bq, low freq, many artifacts, many samples",UPN2_038,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),46559,884,47803,"0,0184925632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"31,16","17,76"
"low bq, low freq, many artifacts, many samples",UPN2_039,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20967,435,21529,"0,0202053045",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"31,18","18,6"
"low bq, many samples",UPN2_008,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),62603,1437,64544,"0,022263882",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"32,06","17,87"
"low bq, many samples",UPN2_010,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),35099,821,36196,"0,0226820643",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"32,08","17,95"
"low bq, low freq, many artifacts, many samples",UPN2_059,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),13194,240,13570,"0,0176860722",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"30,69","16,47"
"low bq, low freq, many artifacts, many samples",UPN2_060,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20220,393,20842,"0,0188561558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"30,7","18,02"
"low bq, low freq, many artifacts, many samples",UPN2_040,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17276,322,17713,"0,0181787388",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"31,11","18,47"
"low bq, low freq, many artifacts, many samples",UPN2_061,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20382,375,21003,"0,0178545922",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"30,81","17,5"
"low bq, low freq, many artifacts, many samples",UPN2_062,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19362,339,19914,"0,0170231998",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"30,89","16,95"
"low bq, low freq, many artifacts, many samples",UPN2_063,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18663,337,19207,"0,0175456865",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"30,78","16,63"
"low bq, low freq, many artifacts, many samples",UPN2_064,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10365,216,10674,"0,0202360877",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"30,75","16,17"
"low bq, low freq, many artifacts, many samples",UPN2_065,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),12444,249,12840,"0,0193925234",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"30,73","16,96"
"low bq, low freq, many artifacts, many samples",UPN2_066,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18194,329,18739,"0,0175569668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"30,64","16,66"
"low bq, low freq, many artifacts, many samples",UPN2_067,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16832,318,17349,"0,0183295867",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"30,69","16,7"
"low bq, low freq, many artifacts, many samples",UPN2_068,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),14764,259,15186,"0,0170551824",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"30,84","16,59"
"low bq, low freq, many artifacts, many samples",UPN2_069,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20105,416,20725,"0,0200723764",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"30,84","18,4"
"low bq, low freq, many artifacts, many samples",UPN2_070,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),12697,213,13029,"0,0163481464",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"30,86","16,16"
"low bq, low freq, many artifacts, many samples",UPN2_071,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15626,243,16024,"0,0151647529",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"30,87","16,99"
"low bq, low freq, many artifacts, many samples",UPN2_072,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15115,267,15548,"0,0171726267",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"30,87","16,88"
"low bq, low freq, many artifacts, many samples",UPN2_073,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10761,172,11059,"0,0155529433",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"30,73","16,5"
"low bq, low freq, many artifacts, many samples",UPN2_074,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10375,207,10692,"0,0193602694",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"30,7","18,12"
"low bq, low freq, many artifacts, many samples",UPN2_075,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22053,426,22741,"0,0187326855",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"30,65","17,19"
"low bq, low freq, many artifacts, many samples",UPN2_076,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18719,404,19337,"0,0208925893",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"30,84","17,16"
"low bq, low freq, many artifacts, many samples",UPN2_077,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19773,386,20399,"0,0189224962",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"30,7","16,1"
"low bq, low freq, many artifacts, many samples",UPN2_078,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19922,346,20492,"0,0168846379",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"30,85","17,36"
"low bq, low freq, many artifacts, many samples",UPN2_079,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),12971,255,13373,"0,0190682719",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"30,83","17,5"
"low bq, low freq, many artifacts, many samples",UPN2_080,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19515,352,20094,"0,017517667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"30,74","16,73"
"low bq, low freq, many artifacts, many samples",UPN2_081,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16215,299,16697,"0,0179074085",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"30,63","17,33"
"low bq, low freq, many artifacts, many samples",UPN2_082,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19396,352,19955,"0,0176396893",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"30,75","16,95"
"low bq, low freq, many artifacts, many samples",UPN2_083,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21967,368,22604,"0,0162803044",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"30,79","16,83"
"low bq, low freq, many artifacts, many samples",UPN2_084,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20268,375,20894,"0,0179477362",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"30,76","16,29"
"low bq, low freq, many artifacts, many samples",UPN2_085,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15295,311,15764,"0,0197284953",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"30,65","17,18"
"low bq, low freq, many artifacts, many samples",UPN2_086,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10578,200,10902,"0,0183452578",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"30,72","17,98"
"low bq, low freq, many artifacts, many samples",UPN2_087,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20684,384,21313,"0,0180171726",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"30,68","17,4"
"low bq, low freq, many artifacts",UPN2_088,20,31023034,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro840Leu/c.2519C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15169,245,15605,"0,0157000961",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,147,Tolerated,"30,63","16,59"
"low bq, many samples",UPN2_014,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),25728,1028,26814,"0,0383381815",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,65","25,31"
"low bq, many samples",UPN2_015,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),33972,1495,35534,"0,0420723814",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,69","24,83"
"low bq, many samples",UPN2_016,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17223,714,17954,"0,0397682968",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,59","24,71"
"low bq, many samples",UPN2_017,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),11610,451,12092,"0,0372973867",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,7","25,06"
"low bq, many samples",UPN2_018,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17297,744,18078,"0,041154995",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,63","24,33"
"low bq, many samples",UPN2_019,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19033,764,19852,"0,0384847874",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,65","24,61"
"low bq, many samples",UPN2_020,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16766,672,17487,"0,0384285469",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,7","24,6"
"low bq, many samples",UPN2_021,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19702,817,20543,"0,039770238",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,68","24,47"
"low bq, many samples",UPN2_022,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),25706,1108,26884,"0,041214105",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,57","24,67"
"low bq, many samples",UPN2_023,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),28194,1216,29484,"0,0412427079",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,56","24,75"
"low bq, many samples",UPN2_024,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),12905,538,13464,"0,0399584076",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,64","24,29"
"low bq, many samples",UPN2_025,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),30715,1304,32088,"0,0406382448",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,62","25,28"
"low bq, many samples",UPN2_026,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),30186,1314,31549,"0,0416494976",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,63","24,93"
"low bq, many samples",UPN2_027,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),32168,1462,33679,"0,04340984",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,6","24,76"
"low bq, many samples",UPN2_089,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19753,1108,20920,"0,0529636711",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,43","24,02"
"low bq, many samples",UPN2_042,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),32147,1432,33684,"0,0425127657",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,18","22,74"
"low bq, many samples",UPN2_028,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22895,984,23910,"0,0411543287",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,63","25,03"
"low bq, many samples",UPN2_043,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),27889,1251,29255,"0,042761921",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,24","22,9"
"low bq, many samples",UPN2_030,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),27334,1241,28650,"0,0433158813",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,6","24,55"
"low bq, many samples",UPN2_031,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18160,807,18996,"0,0424826279",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,58","24,19"
"low bq, many samples",UPN2_045,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),39030,1860,41041,"0,0453205331",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,19","22,41"
"low bq, many samples",UPN2_046,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),36633,1723,38455,"0,044805617",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,22","23,05"
"low bq, many samples",UPN2_033,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21174,947,22171,"0,0427134545",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,58",25
"low bq, many samples",UPN2_047,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),38508,1647,40336,"0,0408320111",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,15","22,29"
"low bq, many samples",UPN2_036,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),23095,957,24090,"0,0397260274",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,67","24,4"
"low bq, many samples",UPN2_050,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),36274,1623,37995,"0,0427161469",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,19","22,59"
"low bq, many samples",UPN2_037,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),42604,1782,44463,"0,0400782673",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,63","24,65"
"low bq, many samples",UPN2_038,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),46842,1954,48914,"0,0399476632",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,64","24,66"
"low bq, many samples",UPN2_053,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),41416,1854,43423,"0,042696267",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,14","22,47"
"low bq, many samples",UPN2_007,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),45664,1812,47579,"0,0380840287",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"33,25","23,11"
"low bq, many samples",UPN2_008,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),63109,2450,65654,"0,0373168428",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"33,3","23,15"
"low bq, many samples",UPN2_009,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),53908,2061,56069,"0,03675828",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"33,25","23,24"
"low bq, many samples",UPN2_010,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),35359,1391,36823,"0,0377753035",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"33,28","23,23"
"low bq, many samples",UPN2_011,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),40843,1632,42586,"0,0383224534",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"33,22","23,01"
"low bq, many samples",UPN2_055,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),41292,1821,43228,"0,0421254742",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,18","22,48"
"low bq, many samples",UPN2_057,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),34676,1587,36397,"0,0436024947",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,11","22,53"
"low bq, many samples",UPN2_058,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),31285,1401,32784,"0,0427342606",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,27","22,55"
"low bq, many samples",UPN2_012,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22431,849,23350,"0,036359743",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"33,25","22,74"
"low bq, many samples",UPN2_060,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20280,815,21205,"0,0384343315",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"31,57","21,33"
low bq,UPN2_040,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17319,746,18105,"0,0412040873",0,0,0,0,0,1,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,"0,006",Damaging,"32,6","24,5"
"low bq, many samples",UPN2_061,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20437,822,21386,"0,0384363602",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"31,63","21,77"
"low bq, many samples",UPN2_063,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18692,696,19510,"0,0356740133",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"31,59","21,53"
"low bq, many samples",UPN2_065,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),12510,470,13044,"0,0360318921",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"31,59","21,59"
"low bq, many samples",UPN2_068,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),14790,567,15439,"0,0367251765",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"31,61","21,31"
"low bq, many samples",UPN2_072,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15168,563,15800,"0,0356329114",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"31,64","21,83"
"low bq, many samples",UPN2_074,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10415,441,10898,"0,0404661406",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"31,46","21,58"
"low bq, many samples",UPN2_075,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22116,884,23132,"0,0382154591",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"31,53","21,25"
"low bq, many samples",UPN2_076,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18800,768,19660,"0,0390640895",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"31,55","21,76"
"low bq, many samples",UPN2_079,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),13008,535,13602,"0,0393324511",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"31,67","21,11"
"low bq, many samples",UPN2_083,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22014,846,22982,"0,0368114176",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"31,59","21,77"
"low bq, many samples",UPN2_084,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20290,843,21269,"0,0396351497",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"31,62","21,71"
"low bq, many samples",UPN2_085,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15343,633,16042,"0,0394589203",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"31,46","21,34"
"low bq, many samples",UPN2_087,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20744,782,21631,"0,0361518191",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"31,46","21,47"
"low bq, many samples",UPN2_088,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15219,602,15893,"0,0378783112",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"31,41","22,01"
"low bq, many samples",UPN2_094,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22955,1361,24377,"0,0558313164",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,5","24,02"
"low bq, many samples",UPN2_095,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19106,1113,20282,"0,0548762449",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,4","24,54"
"low bq, many samples",UPN2_096,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21005,1180,22249,"0,0530360915",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,4","24,72"
"low bq, many samples",UPN2_100,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16773,995,17821,"0,055833006",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,5","24,13"
"low bq, many samples",UPN2_102,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18301,1073,19437,"0,0552039924",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,36","24,41"
"low bq, many samples",UPN2_103,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17547,1031,18625,"0,0553557047",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,41","23,56"
"low bq, many samples",UPN2_104,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22520,1267,23864,"0,0530925243",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,48","24,58"
"low bq, many samples",UPN2_105,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20194,1200,21457,"0,0559258051",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,39","24,12"
"low bq, many samples",UPN2_107,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),31368,1918,33411,"0,0574062435",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,45","24,16"
"low bq, many samples",UPN2_108,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),26441,1616,28107,"0,0574945743",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,46","23,98"
"low bq, many samples",UPN2_109,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),25615,1564,27229,"0,0574387601",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,46","24,1"
"low bq, many samples",UPN2_110,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),29393,1930,31392,"0,061480632",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,47","24,72"
low bq,UPN2_111,20,31023036,G,T,missense_variant(MODERATE|MISSENSE|Gta/Tta|p.Val841Leu/c.2521G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22387,1378,23839,"0,0578044381",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,6,Damaging,"32,41","24,02"
"low bq, many samples",UPN2_001,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15852,697,16616,"0,0419475205",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"33,87","23,44"
"low bq, many samples",UPN2_014,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),25480,1228,26817,"0,0457918485",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,16","24,21"
"low bq, many samples",UPN2_015,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),33722,1728,35535,"0,0486281131",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,11","24,5"
"low bq, many samples",UPN2_016,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17065,828,17954,"0,0461178567",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,14","23,82"
"low bq, many samples",UPN2_017,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),11526,548,12093,"0,0453154718",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,21","25,26"
"low bq, many samples",UPN2_018,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17151,857,18080,"0,0474004425",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,06","24,15"
"low bq, many samples",UPN2_019,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18880,901,19852,"0,0453858553",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,12","24,36"
"low bq, many samples",UPN2_020,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16591,796,17487,"0,0455195288",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,04","23,91"
"low bq, many samples",UPN2_021,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19553,934,20544,"0,0454633956",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,09","24,39"
"low bq, many samples",UPN2_002,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20622,942,21624,"0,0435627081",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"33,75","23,66"
"low bq, many samples",UPN2_022,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),25473,1297,26884,"0,0482443089",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,12","24,52"
"low bq, many samples",UPN2_023,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),27937,1416,29485,"0,0480244192",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,1","24,32"
"low bq, many samples",UPN2_024,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),12773,648,13465,"0,0481247679",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,09","23,87"
"low bq, many samples",UPN2_025,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),30460,1517,32089,"0,0472747671",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,06","24,06"
"low bq, many samples",UPN2_026,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),29922,1524,31554,"0,0482981555",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,17","24,46"
"low bq, many samples",UPN2_004,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3461,181,3662,"0,0494265429",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"33,6","23,32"
"low bq, many samples",UPN2_027,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),31853,1702,33681,"0,0505329414",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,12","24,41"
"low bq, many samples",UPN2_089,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19896,975,20918,"0,0466105746",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,07","24,37"
"low bq, many samples",UPN2_042,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),31906,1647,33698,"0,0488753042",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"33,37","23,45"
"low bq, many samples",UPN2_028,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22671,1146,23929,"0,0478916796",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,05","24,51"
"low bq, many samples",UPN2_043,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),27604,1503,29262,"0,0513635432",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"33,4","23,57"
"low bq, many samples",UPN2_044,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),6984,395,7409,"0,0533135376",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"33,4","25,51"
"low bq, many samples",UPN2_029,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),27368,1419,28894,"0,049110542",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,04","24,27"
"low bq, many samples",UPN2_030,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),27135,1420,28650,"0,0495636998",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,13","24,08"
"low bq, many samples",UPN2_031,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17996,932,18996,"0,0490629606",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,14","24,32"
"low bq, many samples",UPN2_045,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),38801,2030,41056,"0,049444661",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"33,31","23,67"
"low bq, many samples",UPN2_032,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),9696,465,10201,"0,0455837663",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,09","23,29"
"low bq, many samples",UPN2_046,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),36296,1981,38466,"0,051500026",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"33,35","23,86"
"low bq, many samples",UPN2_033,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20981,1116,22172,"0,0503337543",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,12","24,29"
"low bq, many samples",UPN2_034,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),8180,386,8597,"0,0448993835",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,12","24,05"
"low bq, many samples",UPN2_047,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),38119,2042,40340,"0,0506197323",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"33,18","23,02"
"low bq, many samples",UPN2_048,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4722,234,5001,"0,0467906419",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"33,17","22,09"
"low bq, many samples",UPN2_035,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22774,1177,24022,"0,048996753",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,12","24,12"
"low bq, many samples",UPN2_036,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22887,1106,24095,"0,0459016393",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,03","24,01"
"low bq, many samples",UPN2_006,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),7131,312,7469,"0,0417726603",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"33,75","23,87"
"low bq, many samples",UPN2_049,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17393,942,18406,"0,0511789634",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"33,31","23,44"
"low bq, many samples",UPN2_050,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),35928,1883,37996,"0,0495578482",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"33,25","23,36"
"low bq, many samples",UPN2_037,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),42290,2043,44470,"0,0459410839",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,11","24,41"
"low bq, many samples",UPN2_051,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),27950,1421,29517,"0,0481417488",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"33,33","23,53"
"low bq, many samples",UPN2_052,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),31698,1648,33524,"0,0491588116",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"33,35","23,63"
"low bq, many samples",UPN2_038,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),46461,2267,48915,"0,0463457017",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,13","23,79"
"low bq, many samples",UPN2_039,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20882,1013,21992,"0,0460622044",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,09","24,3"
"low bq, many samples",UPN2_053,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),41076,2132,43429,"0,0490916208",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"33,28","23,44"
"low bq, many samples",UPN2_054,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),26093,1386,27619,"0,0501828451",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"33,33","23,59"
"low bq, many samples",UPN2_007,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),45266,2170,47580,"0,0456073981",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"33,8","23,43"
"low bq, many samples",UPN2_008,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),62556,2895,65662,"0,0440894277",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"33,8","23,41"
"low bq, many samples",UPN2_009,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),53431,2460,56066,"0,0438768594",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"33,81","23,43"
"low bq, many samples",UPN2_010,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),35052,1638,36823,"0,0444830676",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"33,77","23,34"
"low bq, many samples",UPN2_011,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),40443,1981,42593,"0,0465099899",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"33,62","23,66"
"low bq, many samples",UPN2_055,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),40810,2186,43234,"0,0505620576",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"33,22","23,77"
"low bq, many samples",UPN2_056,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4126,207,4344,"0,0476519337",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"33,31","23,27"
"low bq, many samples",UPN2_090,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18006,925,18991,"0,0487072824",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,02","23,89"
"low bq, many samples",UPN2_057,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),34394,1847,36404,"0,0507361828",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"33,33","23,37"
"low bq, many samples",UPN2_058,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),31099,1559,32789,"0,0475464333",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"33,41","23,49"
"low bq, many samples",UPN2_059,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),13266,490,13827,"0,0354379113",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"32,55","21,23"
"low bq, many samples",UPN2_012,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22233,1028,23349,"0,0440275815",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"33,79","23,79"
"low bq, many samples",UPN2_060,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20380,753,21214,"0,0354954275",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"32,6","21,37"
"low bq, many samples",UPN2_040,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17158,852,18106,"0,0470562245",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,05","24,63"
"low bq, many samples",UPN2_013,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),13350,643,14059,"0,0457358276",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"33,79","23,7"
"low bq, many samples",UPN2_091,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),12248,613,12924,"0,0474311359",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,11","24,24"
"low bq, many samples",UPN2_092,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10911,629,11595,"0,0542475205",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"33,99","24,74"
low bq,UPN2_093,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),11917,689,12657,"0,0544362803",0,0,0,0,0,1,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,08","24,09"
"low bq, many samples",UPN2_061,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20522,744,21383,"0,0347939952",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"32,59","21,64"
"low bq, many samples",UPN2_062,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19465,687,20260,"0,0339091807",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"32,61","21,32"
"low bq, many samples",UPN2_063,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18711,697,19518,"0,0357106261",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"32,45","21,35"
"low bq, many samples",UPN2_064,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10425,378,10853,"0,0348290795",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"32,57","21,41"
"low bq, many samples",UPN2_066,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18342,659,19072,"0,0345532718",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"32,68","21,22"
"low bq, many samples",UPN2_067,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16942,639,17642,"0,0362203832",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"32,75","20,89"
"low bq, many samples",UPN2_068,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),14876,511,15441,"0,0330937115",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"32,66","21,91"
"low bq, many samples",UPN2_069,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20266,766,21131,"0,0362500592",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"32,61","21,86"
"low bq, many samples",UPN2_070,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),12755,419,13254,"0,0316130979",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"32,49","21,6"
"low bq, many samples",UPN2_071,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15665,544,16286,"0,0334029228",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"32,55","21,45"
"low bq, many samples",UPN2_072,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15198,541,15805,"0,0342296742",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"32,76","21,62"
"low bq, many samples",UPN2_073,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10842,374,11257,"0,0332237719",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"32,63","21,66"
"low bq, many samples",UPN2_074,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10467,407,10904,"0,037325752",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"32,56","21,78"
"low bq, many samples",UPN2_075,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22266,783,23139,"0,0338389732",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"32,62","21,17"
"low bq, many samples",UPN2_076,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18886,682,19661,"0,0346879609",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"32,52","21,53"
"low bq, many samples",UPN2_077,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19861,752,20733,"0,0362706796",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"32,62","20,71"
"low bq, many samples",UPN2_078,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20047,724,20864,"0,0347009202",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"32,58","21,85"
"low bq, many samples",UPN2_079,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),13050,507,13604,"0,0372684505",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"32,57","21,18"
"low bq, many samples",UPN2_080,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19605,688,20400,"0,0337254902",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"32,67","21,23"
"low bq, many samples",UPN2_081,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16322,583,16977,"0,0343405784",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"32,66","21,85"
"low bq, many samples",UPN2_082,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19539,660,20289,"0,0325299423",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"32,68","21,08"
"low bq, many samples",UPN2_083,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22072,798,22984,"0,0347198051",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"32,6","21,96"
"low bq, many samples",UPN2_084,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20394,781,21273,"0,0367132045",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"32,62","21,51"
"low bq, many samples",UPN2_085,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15421,565,16044,"0,0352156569",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"32,57","20,74"
"low bq, many samples",UPN2_086,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10671,353,11074,"0,0318764674",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"32,55","21,18"
"low bq, many samples",UPN2_087,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20786,762,21632,"0,0352255917",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"32,47","21,45"
"low bq, many samples",UPN2_088,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15286,539,15898,"0,0339036357",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"32,65","21,83"
"low bq, many samples",UPN2_094,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),23135,1173,24380,"0,0481132075",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,01","24,84"
"low bq, many samples",UPN2_095,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19237,983,20285,"0,0484594528",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,05","23,9"
"low bq, many samples",UPN2_096,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21115,1078,22250,"0,0484494382",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"33,95","24,64"
"low bq, many samples",UPN2_097,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),23885,1238,25197,"0,0491328333",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,05","24,62"
"low bq, many samples",UPN2_098,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17370,948,18377,"0,0515862219",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"33,98","23,88"
"low bq, many samples",UPN2_099,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10775,549,11348,"0,0483785689",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,05","24,52"
"low bq, many samples",UPN2_100,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16880,891,17823,"0,0499915839",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,09","24,46"
"low bq, many samples",UPN2_101,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17702,966,18753,"0,0515117581",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"33,97","24,63"
"low bq, many samples",UPN2_102,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18370,982,19436,"0,0505247993",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"33,96","24,34"
"low bq, many samples",UPN2_103,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17668,913,18628,"0,0490122396",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"33,98","24,28"
"low bq, many samples",UPN2_104,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22635,1172,23869,"0,0491013448",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"33,91","24,58"
"low bq, many samples",UPN2_105,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20349,1059,21464,"0,0493384271",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,12","24,13"
"low bq, many samples",UPN2_106,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),23131,1199,24437,"0,0490649425",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,12","24,37"
"low bq, many samples",UPN2_107,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),31621,1694,33417,"0,0506927612",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,04","24,36"
"low bq, many samples",UPN2_108,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),26589,1435,28112,"0,0510458167",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,01","24,18"
"low bq, many samples",UPN2_109,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),25767,1378,27224,"0,0506171026",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,07","24,11"
"low bq, many samples",UPN2_110,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),29618,1690,31393,"0,0538336572",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,03","24,57"
low bq,UPN2_111,20,31023040,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn842Ile/c.2525A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22546,1205,23845,"0,0505347033",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,0,Damaging,"34,03","24,58"
"low bq, low freq, many artifacts, many samples",UPN2_048,20,31023053,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser846Arg/c.2538T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),2547,26,2582,"0,0100697134",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,3,Damaging,"29,81",14
"low bq, low freq, many artifacts, many samples",UPN2_078,20,31023053,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser846Arg/c.2538T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),10197,110,10346,"0,0106321284",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,3,Damaging,"30,02","14,48"
"low freq, many artifacts",UPN2_056,20,31023061,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro849Leu/c.2546C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),2158,40,2209,"0,0181077411",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,45",Neutral,"0,002",Damaging,"33,75","32,45"
"inspected, bad alignment, many artifacts",UPN2_048,20,31023063,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu850*/c.2548G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),2200,413,2618,"0,1577540107",1,0,0,0,1,0,0,1,3,NO,NO,COSM1155828,Something is odd...,0,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,72","27,95"
"low freq, many artifacts, many samples",UPN2_006,20,31023069,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser852Ala/c.2554T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),6667,69,6782,"0,01017399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,93",Neutral,914,Tolerated,"32,43","31,26"
"low freq, many artifacts, many samples",UPN2_059,20,31023069,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser852Ala/c.2554T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),23807,248,24180,"0,0102564103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,93",Neutral,914,Tolerated,"31,8","30,3"
"many samples, low freq, neutral effect",UPN2_060,20,31023069,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser852Ala/c.2554T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),24049,271,24486,"0,0110675488",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,93",Neutral,"0,914",Tolerated,"31,9","30,46"
"many samples, low freq, neutral effect",UPN2_061,20,31023069,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser852Ala/c.2554T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),22863,298,23290,"0,0127951911",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,93",Neutral,"0,914",Tolerated,"31,94","30,41"
"many samples, low freq, neutral effect",UPN2_062,20,31023069,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser852Ala/c.2554T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),21133,265,21526,"0,012310694",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,93",Neutral,"0,914",Tolerated,"31,93","30,49"
"many samples, low freq, neutral effect",UPN2_063,20,31023069,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser852Ala/c.2554T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),21371,294,21792,"0,0134911894",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,93",Neutral,"0,914",Tolerated,"31,82","30,53"
"low freq, many artifacts, many samples",UPN2_064,20,31023069,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser852Ala/c.2554T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),17260,279,17654,"0,0158037838",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,93",Neutral,914,Tolerated,"31,74","31,34"
"many samples, low freq, neutral effect",UPN2_065,20,31023069,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser852Ala/c.2554T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),18722,206,19067,"0,0108040069",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,93",Neutral,"0,914",Tolerated,"31,85","29,81"
"low freq, many artifacts, many samples",UPN2_066,20,31023069,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser852Ala/c.2554T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),26881,316,27363,"0,0115484413",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,93",Neutral,914,Tolerated,"31,84","30,41"
"many samples, low freq, neutral effect",UPN2_067,20,31023069,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser852Ala/c.2554T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),25164,258,25580,"0,0100860047",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,93",Neutral,"0,914",Tolerated,"31,77","30,1"
"many samples, low freq, neutral effect",UPN2_068,20,31023069,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser852Ala/c.2554T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),20390,239,20764,"0,0115103063",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,93",Neutral,"0,914",Tolerated,"31,88","30,51"
"many samples, low freq, neutral effect",UPN2_069,20,31023069,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser852Ala/c.2554T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),26157,291,26603,"0,0109386159",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,93",Neutral,"0,914",Tolerated,"31,86","30,51"
"many samples, low freq, neutral effect",UPN2_070,20,31023069,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser852Ala/c.2554T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),15778,175,16029,"0,0109177116",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,93",Neutral,"0,914",Tolerated,"31,92","30,35"
"low freq, many artifacts, many samples",UPN2_071,20,31023069,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser852Ala/c.2554T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),16585,192,16840,"0,0114014252",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,93",Neutral,914,Tolerated,"31,92","30,23"
"low freq, many artifacts, many samples",UPN2_072,20,31023069,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser852Ala/c.2554T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),16695,204,16986,"0,0120098905",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,93",Neutral,914,Tolerated,32,"30,36"
"many samples, low freq, neutral effect",UPN2_073,20,31023069,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser852Ala/c.2554T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),14801,192,15080,"0,0127320955",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,93",Neutral,"0,914",Tolerated,"31,82","30,49"
"many samples, low freq, neutral effect",UPN2_074,20,31023069,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser852Ala/c.2554T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),14304,155,14549,"0,0106536532",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,93",Neutral,"0,914",Tolerated,"31,81","30,94"
"many samples, low freq, neutral effect",UPN2_075,20,31023069,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser852Ala/c.2554T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),26325,321,26797,"0,0119789529",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,93",Neutral,"0,914",Tolerated,"31,91","30,5"
"many samples, low freq, neutral effect",UPN2_076,20,31023069,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser852Ala/c.2554T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),22351,248,22740,"0,0109058927",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,93",Neutral,"0,914",Tolerated,"31,9","30,42"
"many samples, low freq, neutral effect",UPN2_077,20,31023069,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser852Ala/c.2554T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),25427,313,25886,"0,012091478",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,93",Neutral,"0,914",Tolerated,"31,92","31,02"
"many samples, low freq, neutral effect",UPN2_078,20,31023069,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser852Ala/c.2554T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),22027,257,22420,"0,0114629795",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,93",Neutral,"0,914",Tolerated,"31,98","29,73"
"many samples, low freq, neutral effect",UPN2_079,20,31023069,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser852Ala/c.2554T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),14671,199,14934,"0,013325298",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,93",Neutral,"0,914",Tolerated,"31,88","30,36"
"many samples, low freq, neutral effect",UPN2_080,20,31023069,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser852Ala/c.2554T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),22569,314,22997,"0,0136539549",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,93",Neutral,"0,914",Tolerated,"31,96","30,38"
"many samples, low freq, neutral effect",UPN2_081,20,31023069,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser852Ala/c.2554T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),22515,271,22909,"0,011829412",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,93",Neutral,"0,914",Tolerated,"31,84","30,84"
"low freq, many artifacts, many samples",UPN2_083,20,31023069,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser852Ala/c.2554T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),26740,399,27327,"0,0146009441",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,93",Neutral,914,Tolerated,"31,94","30,58"
"low freq, many artifacts, many samples",UPN2_084,20,31023069,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser852Ala/c.2554T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),25402,300,25852,"0,011604518",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,93",Neutral,914,Tolerated,"31,88","30,38"
"low freq, many artifacts",UPN2_086,20,31023069,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser852Ala/c.2554T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),16554,212,16881,"0,0125584977",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,93",Neutral,914,Tolerated,"31,84","30,31"
"many samples, low freq, neutral effect",UPN2_087,20,31023069,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser852Ala/c.2554T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),26843,323,27358,"0,0118064186",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,93",Neutral,"0,914",Tolerated,"31,8","30,07"
"many samples, low freq, neutral effect",UPN2_088,20,31023069,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser852Ala/c.2554T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),20762,244,21123,"0,0115513895",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,93",Neutral,"0,914",Tolerated,"31,93","30,36"
"low freq, many artifacts",UPN2_044,20,31023091,AC,A,frameshift_variant(HIGH||aac/|p.Asn859fs/c.2577delC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),6455,94,6566,"0,0143161742",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,86",NA
many samples,UPN2_001,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),13609,593,14247,"0,0416227978",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,33,Damaging,"32,46","31,35"
" many samples, strandbias",UPN2_014,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),25016,668,25753,"0,0259387256",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,74","31,24"
"low freq, many artifacts, many samples",UPN2_015,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),33187,646,33945,"0,0190307851",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,33,Damaging,"32,72","31,25"
many samples,UPN2_016,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16356,439,16851,"0,0260518664",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,33,Damaging,"32,71","31,41"
many samples,UPN2_017,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),11168,322,11511,"0,027973243",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,33,Damaging,"32,82","31,72"
many samples,UPN2_018,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16956,397,17423,"0,0227859726",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,33,Damaging,"32,69","31,49"
" many samples, strandbias",UPN2_019,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),18481,514,19048,"0,0269844603",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,76","31,42"
" many samples, strandbias",UPN2_020,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16779,427,17263,"0,0247349823",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,79","31,44"
many samples,UPN2_021,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),18473,570,19109,"0,0298288764",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,33,Damaging,"32,7","31,59"
" many samples, strandbias",UPN2_002,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),18492,846,19390,"0,0436307375",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,57","31,36"
many samples,UPN2_003,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3604,151,3763,"0,0401275578",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,33,Damaging,"32,68","31,56"
" many samples, strandbias",UPN2_022,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),24987,629,25690,"0,0244842351",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,69","31,25"
" many samples, strandbias",UPN2_023,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),27805,700,28580,"0,0244926522",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,77","31,31"
" many samples, strandbias",UPN2_024,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),12543,264,12846,"0,0205511443",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,69","31,11"
" many samples, strandbias",UPN2_025,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),30099,748,30948,"0,0241695748",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,76","31,51"
" many samples, strandbias",UPN2_026,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),29787,793,30667,"0,0258584146",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,81","31,4"
many samples,UPN2_004,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3537,156,3702,"0,0421393841",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,33,Damaging,"32,81","31,37"
many samples,UPN2_027,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),31450,865,32414,"0,0266859999",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,33,Damaging,"32,72","31,34"
" many samples, strandbias",UPN2_028,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),22674,560,23320,"0,0240137221",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,8","31,54"
"inspected, many samples, strandbias",UPN2_043,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),30022,349,30493,"0,0114452497",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,28","29,99"
"low freq, many artifacts, many samples",UPN2_044,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6391,95,6530,"0,0145482389",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,33,Damaging,"31,99","31,01"
" many samples, strandbias",UPN2_029,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),27895,722,28687,"0,0251681947",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,82","31,5"
" many samples, strandbias",UPN2_030,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),26222,665,26966,"0,0246606838",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,64","31,65"
many samples,UPN2_031,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),17711,423,18191,"0,0232532571",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,33,Damaging,"32,67","31,59"
many samples,UPN2_005,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),5798,290,6104,"0,0475098296",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,33,Damaging,"32,45","31,36"
" many samples, strandbias",UPN2_032,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),9750,222,10011,"0,0221756068",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,83","31,46"
"low freq, many artifacts, many samples",UPN2_046,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),37861,629,38620,"0,016286898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,33,Damaging,"32,23","30,85"
" many samples, strandbias",UPN2_033,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),20641,488,21191,"0,0230286442",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,68","31,44"
"low freq, many artifacts, many samples",UPN2_034,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),8101,173,8299,"0,020845885",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,33,Damaging,"32,79","31,31"
" many samples, strandbias",UPN2_047,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),49068,527,49763,"0,0105901975",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,61",30
many samples,UPN2_035,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),22751,557,23392,"0,0238115595",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,33,Damaging,"32,78","31,27"
" many samples, strandbias",UPN2_036,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),22815,576,23464,"0,0245482441",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,84","31,49"
many samples,UPN2_006,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6428,315,6762,"0,0465838509",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,33,Damaging,"32,64","31,75"
" many samples, strandbias",UPN2_049,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),22550,246,22882,"0,0107508085",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,63","30,42"
"low freq, many artifacts, many samples",UPN2_037,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),42110,872,43097,"0,0202334269",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,33,Damaging,"32,8","31,61"
" many samples, strandbias",UPN2_038,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),46134,1075,47329,"0,022713347",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,78","31,25"
" many samples, strandbias",UPN2_039,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),20680,491,21262,"0,0230928417",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,82","31,36"
"low freq, many artifacts, many samples",UPN2_053,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),41280,588,42001,"0,0139996667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,33,Damaging,"32,08","30,41"
many samples,UPN2_007,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),41469,1340,42915,"0,0312245136",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,33,Damaging,"32,53","31,26"
many samples,UPN2_008,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),57399,1796,59364,"0,030254026",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,33,Damaging,"32,57","31,3"
" many samples, strandbias",UPN2_009,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),48653,1334,50145,"0,0266028517",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,53","31,2"
many samples,UPN2_010,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),32098,933,33116,"0,0281736925",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,33,Damaging,"32,58","31,37"
many samples,UPN2_011,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),38683,1314,40160,"0,0327191235",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,33,Damaging,"32,63","31,44"
" many samples, strandbias",UPN2_055,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),44241,459,44848,"0,0102345701",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,24","30,45"
"low freq, many artifacts, many samples",UPN2_057,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),36530,451,37102,"0,0121556789",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,33,Damaging,"32,21","30,49"
"low freq, many artifacts, many samples",UPN2_058,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),33639,594,34346,"0,0172945903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,33,Damaging,"32,28","30,65"
" many samples, strandbias",UPN2_059,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),23745,356,24179,"0,0147235204",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"33,23","30,06"
" many samples, strandbias",UPN2_012,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),20102,657,20820,"0,031556196",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,56","31,35"
" many samples, strandbias",UPN2_060,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),23674,668,24420,"0,0273546274",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,65","30,94"
many samples,UPN2_040,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16795,414,17260,"0,023986095",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,33,Damaging,"32,77","31,6"
" many samples, strandbias",UPN2_013,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),11860,428,12332,"0,0347064548",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,51","31,43"
" many samples, strandbias",UPN2_061,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),22411,731,23209,"0,0314964023",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,53","30,97"
" many samples, strandbias",UPN2_062,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),20631,747,21445,"0,0348332945",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,48","30,95"
" many samples, strandbias",UPN2_063,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),20937,718,21705,"0,0330799355",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,53","31,01"
" many samples, strandbias",UPN2_064,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),17191,393,17641,"0,0222776487",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"33,19","30,2"
"low freq, many artifacts, many samples",UPN2_065,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),18675,364,19102,"0,0190555963",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,33,Damaging,"33,04","30,55"
" many samples, strandbias",UPN2_066,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),26688,559,27332,"0,0204522172",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,96","30,57"
" many samples, strandbias",UPN2_067,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),24945,561,25574,"0,0219363416",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,96","30,55"
" many samples, strandbias",UPN2_068,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),20240,458,20770,"0,0220510351",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,95","30,73"
many samples,UPN2_069,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),25798,692,26566,"0,0260483325",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,33,Damaging,"32,8","31,08"
many samples,UPN2_070,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),15528,427,15990,"0,0267041901",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,33,Damaging,"32,85","30,75"
many samples,UPN2_071,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16079,568,16695,"0,0340221623",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,33,Damaging,"32,41","31,14"
" many samples, strandbias",UPN2_072,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16285,591,16911,"0,0349476672",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,54","30,91"
" many samples, strandbias",UPN2_073,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),14642,341,15047,"0,0226623247",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,89","30,9"
" many samples, strandbias",UPN2_074,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),14177,317,14548,"0,0217899368",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,86","30,35"
" many samples, strandbias",UPN2_075,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),25927,697,26716,"0,0260892349",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,64","30,86"
" many samples, strandbias",UPN2_076,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),21987,586,22658,"0,0258628299",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,66","30,6"
" many samples, strandbias",UPN2_077,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),25196,526,25790,"0,0203955021",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,78","30,75"
" many samples, strandbias",UPN2_078,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),21657,615,22328,"0,0275438911",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,54","30,82"
" many samples, strandbias",UPN2_079,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),14406,417,14881,"0,0280223103",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,49","30,42"
" many samples, strandbias",UPN2_080,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),22244,620,22905,"0,0270683257",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,64","30,81"
" many samples, strandbias",UPN2_081,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),22342,428,22849,"0,0187316732",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,86",31
"low freq, many artifacts, many samples",UPN2_082,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),25368,431,25882,"0,0166524998",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,33,Damaging,"32,76","30,15"
" many samples, strandbias",UPN2_083,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),26366,799,27235,"0,0293372499",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,77","30,89"
" many samples, strandbias",UPN2_084,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),25167,560,25807,"0,0216995389",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,72","30,53"
" many samples, strandbias",UPN2_085,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),20904,400,21391,"0,018699453",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,84","30,65"
"low freq, many artifacts, many samples",UPN2_086,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16533,272,16858,"0,0161347728",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,33,Damaging,"32,99","30,83"
"low freq, many artifacts",UPN2_087,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),26605,580,27275,"0,0212648946",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,33,Damaging,"32,7","30,37"
" many samples, strandbias",UPN2_088,20,31023123,G,C,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly870Arg/c.2608G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),20535,494,21086,"0,0234278668",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,033",Damaging,"32,9","30,51"
"low freq, many artifacts",UPN2_056,20,31023131,C,A,stop_gained(HIGH|NONSENSE|tgC/tgA|p.Cys872*/c.2616C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),4746,49,4809,"0,0101892285",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,92","32,55"
"low bq, low freq, many artifacts, many samples",UPN2_049,20,31023139,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met875Lys/c.2624T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),13406,149,13616,"0,0109430082",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,47,Damaging,"33,73","20,86"
"low bq, low freq, many artifacts, many samples",UPN2_058,20,31023139,T,A,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met875Lys/c.2624T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),17587,184,17832,"0,0103185285",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,28",Neutral,47,Damaging,"33,83","18,49"
"low freq, many artifacts, many samples",UPN2_056,20,31023184,T,A,missense_variant(MODERATE|MISSENSE|cTc/cAc|p.Leu890His/c.2669T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),9524,108,9648,"0,0111940299",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,17",Neutral,2,Damaging,"33,62","27,44"
"low bq, low freq, many artifacts, many samples",UPN2_057,20,31023187,T,A,missense_variant(MODERATE|MISSENSE|gTt/gAt|p.Val891Asp/c.2672T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),37065,398,37721,"0,0105511519",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,1,Damaging,"33,01","19,73"
"low bq, low freq, many artifacts, many samples",UPN2_044,20,31023197,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser894Arg/c.2682T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),5580,57,5667,"0,0100582319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,7",Neutral,43,Damaging,"32,75","20,39"
"inspected, many artifacts",UPN2_044,20,31023205,A,T,missense_variant(MODERATE|MISSENSE|cAt/cTt|p.His897Leu/c.2690A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5554,74,5663,"0,0130672788",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,"0,564",Tolerated,"33,63",30
"inspected, many artifacts",UPN2_004,20,31023207,T,A,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp898Arg/c.2692T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),3693,42,3749,"0,0112029875",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,44",Neutral,"0,049",Damaging,"33,77","29,48"
"low bq, low freq, many artifacts, many samples",UPN2_067,20,31023214,C,A,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro900His/c.2699C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),37307,403,37778,"0,0106675843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,01",Deleterious,0,Damaging,"30,54","15,5"
"low bq, low freq, many artifacts, many samples",UPN2_072,20,31023214,C,A,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro900His/c.2699C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),26607,276,26919,"0,0102529812",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,01",Deleterious,0,Damaging,"30,84","19,72"
"low bq, low freq, many artifacts",UPN2_086,20,31023214,C,A,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro900His/c.2699C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),25786,268,26104,"0,0102666258",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,01",Deleterious,0,Damaging,"30,66","15,46"
"strandbias, many samples",UPN2_015,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),23326,316,23651,"0,0133609573",0,0,0,0,1,1,0,0,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,5","35,39"
"low freq, many artifacts",UPN2_017,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),7661,79,7743,"0,0102027638",0,0,0,0,1,0,0,0,1,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,19,Damaging,"35,53","35,9"
"strandbias, many samples",UPN2_018,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),12346,142,12497,"0,0113627271",0,0,0,0,1,1,0,1,3,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,48","35,6"
"strandbias, many samples",UPN2_002,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),11664,120,11792,"0,0101763908",0,0,0,0,1,1,0,1,3,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,4","35,53"
"strandbias, many samples",UPN2_023,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),18347,222,18586,"0,0119444743",0,0,0,0,1,1,0,0,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,5","35,69"
"strandbias, many samples",UPN2_025,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),22105,317,22438,"0,0141278189",0,0,0,0,1,1,0,1,3,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,49","35,66"
"strandbias, many samples",UPN2_026,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),20849,214,21069,"0,0101571029",0,0,0,0,1,1,0,1,3,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,53","35,72"
"inspected, strandbias, many samples",UPN2_004,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),2242,25,2269,"0,0110180696",0,0,0,0,1,0,0,1,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,4",36
"strandbias, many samples",UPN2_089,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),16165,274,16457,"0,0166494501",0,0,0,0,1,1,0,0,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,41","35,77"
"inspected, strandbias, many samples",UPN2_044,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),3772,97,3882,"0,02498712",0,0,0,0,1,1,0,1,3,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,12","35,63"
"strandbias, many samples",UPN2_031,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),12657,137,12800,"0,010703125",0,0,0,0,1,1,0,1,3,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,51",36
"strandbias, many samples",UPN2_035,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),15673,252,15945,"0,0158043274",0,0,0,0,1,1,0,0,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,48","35,82"
"strandbias, many samples",UPN2_037,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),28870,356,29246,"0,0121726048",0,0,0,0,1,1,0,1,3,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,51","35,69"
"strandbias, many samples",UPN2_051,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),21437,305,21768,"0,0140113929",0,0,0,0,1,1,0,1,3,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,13","35,87"
"strandbias, many samples",UPN2_038,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),32101,378,32500,"0,0116307692",0,0,0,0,1,1,0,1,3,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,51","35,75"
"strandbias, many samples",UPN2_053,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),27803,443,28275,"0,0156675508",0,0,0,0,1,1,0,1,3,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,09","35,68"
"strandbias, many samples",UPN2_011,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),26895,398,27308,"0,0145744837",0,0,0,0,1,1,0,0,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,37","35,81"
"strandbias, many samples",UPN2_060,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),23789,624,24438,"0,0255340044",0,0,0,0,1,1,0,0,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,12","35,54"
"strandbias, many samples",UPN2_061,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),21323,776,22138,"0,0350528503",0,0,0,0,1,1,0,0,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,17","35,51"
"strandbias, many samples",UPN2_062,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),20360,313,20689,"0,0151288124",0,0,0,0,1,1,0,0,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,16","35,56"
"strandbias, many samples",UPN2_063,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),20408,331,20756,"0,015947196",0,0,0,0,1,1,0,0,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,13","35,7"
"strandbias, many samples",UPN2_065,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),17888,276,18177,"0,0151840238",0,0,0,0,1,1,0,0,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,05","35,62"
"strandbias, many samples",UPN2_066,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),21302,387,21725,"0,0178135788",0,0,0,0,1,1,0,0,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,03","35,65"
"strandbias, many samples",UPN2_067,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),20898,328,21250,"0,0154352941",0,0,0,0,1,1,0,1,3,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,04","35,55"
"strandbias, many samples",UPN2_068,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),18743,527,19285,"0,027326938",0,0,0,0,1,1,0,0,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,12","35,61"
"strandbias, many samples",UPN2_069,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),25791,593,26430,"0,022436625",0,0,0,0,1,1,0,0,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,13","35,56"
"strandbias, many samples",UPN2_070,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),15209,425,15649,"0,0271582849",0,0,0,0,1,1,0,0,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,11","35,67"
"strandbias, many samples",UPN2_071,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),17381,185,17593,"0,010515546",0,0,0,0,1,1,0,0,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,14","35,72"
"strandbias, many samples",UPN2_072,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),17743,227,17992,"0,0126167185",0,0,0,0,1,1,0,0,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,09","35,44"
"strandbias, many samples",UPN2_073,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),16167,271,16452,"0,0164721614",0,0,0,0,1,1,0,0,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,14","35,82"
"strandbias, many samples",UPN2_074,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),12412,246,12673,"0,019411347",0,0,0,0,1,1,0,0,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,1","35,52"
"strandbias, many samples",UPN2_075,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),27050,425,27508,"0,0154500509",1,0,0,0,1,1,0,0,3,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,15","35,28"
"strandbias, many samples",UPN2_076,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),21323,494,21839,"0,0226200833",0,0,0,0,1,1,0,0,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,16","35,67"
"strandbias, many samples",UPN2_077,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),22913,524,23462,"0,0223339869",0,0,0,0,1,1,0,0,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,11","35,48"
"strandbias, many samples",UPN2_078,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),21338,494,21855,"0,0226035232",0,0,0,0,1,1,0,0,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,15","35,64"
"strandbias, many samples",UPN2_079,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),14212,301,14524,"0,0207243184",0,0,0,0,1,1,0,0,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,15","35,52"
"strandbias, many samples",UPN2_080,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),23031,302,23355,"0,0129308499",0,0,0,0,1,1,0,0,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,15","35,68"
"strandbias, many samples",UPN2_082,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),22310,411,22756,"0,0180611707",0,0,0,0,1,1,0,0,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,06","35,57"
"strandbias, many samples",UPN2_083,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),26425,991,27435,"0,0361217423",0,0,0,0,1,1,0,0,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,14","35,72"
"strandbias, many samples",UPN2_084,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),23114,589,23739,"0,0248114916",0,0,0,0,1,1,0,0,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,15","35,61"
"strandbias, many samples",UPN2_085,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),18227,378,18621,"0,0202996617",0,0,0,0,1,1,0,0,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,02","35,81"
"strandbias, many samples",UPN2_086,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),14637,251,14904,"0,0168411165",0,0,0,0,1,1,0,0,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,05","35,48"
"strandbias, many samples",UPN2_087,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),24742,498,25267,"0,0197095025",0,0,0,0,1,1,0,0,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,04","35,64"
"strandbias, many samples",UPN2_088,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),19425,518,19964,"0,0259467041",0,0,0,0,1,1,0,0,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,13","35,56"
"strandbias, many samples",UPN2_094,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),17734,294,18039,"0,016298021",0,0,0,0,1,1,0,0,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,42","35,62"
"strandbias, many samples",UPN2_095,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),14813,235,15057,"0,0156073587",0,0,0,0,1,1,0,0,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,42","35,93"
"strandbias, many samples",UPN2_096,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),16702,262,16980,"0,0154299176",0,0,0,0,1,1,0,1,3,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,43","35,75"
"strandbias, many samples",UPN2_097,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),18097,284,18393,"0,0154406568",0,0,0,0,1,1,0,0,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,44","35,8"
"strandbias, many samples",UPN2_099,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),8382,94,8478,"0,0110875206",0,0,0,0,1,1,0,0,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,46",36
"strandbias, many samples",UPN2_100,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),14413,302,14730,"0,0205023761",0,0,0,0,1,1,0,0,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,43","35,55"
"strandbias, many samples",UPN2_101,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),15123,174,15311,"0,0113643786",0,0,0,0,1,1,0,1,3,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,43","35,72"
"strandbias, many samples",UPN2_102,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),15215,192,15417,"0,0124537848",0,0,0,0,1,1,0,0,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,41","35,86"
"strandbias, many samples",UPN2_103,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),14631,300,14945,"0,0200736032",0,0,0,0,1,1,0,1,3,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,47","35,67"
"strandbias, many samples",UPN2_104,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),18174,309,18498,"0,0167045086",0,0,0,0,1,1,0,0,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,41","35,6"
"strandbias, many samples",UPN2_105,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),16193,332,16537,"0,0200761928",0,0,0,0,1,1,0,0,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,42","35,81"
"strandbias, many samples",UPN2_106,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),19704,225,19948,"0,0112793262",0,0,0,0,1,1,0,1,3,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,42","35,75"
"strandbias, many samples",UPN2_107,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),24326,292,24637,"0,0118520924",0,0,0,0,1,1,0,1,3,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,42","35,75"
"strandbias, many samples",UPN2_108,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),22960,359,23340,"0,0153813196",0,0,0,0,1,1,0,0,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,42","35,79"
"strandbias, many samples",UPN2_109,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),21680,411,22103,"0,0185947609",0,0,0,0,1,1,0,0,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,47","35,72"
"strandbias, many samples",UPN2_110,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),23125,426,23568,"0,0180753564",0,0,0,0,1,1,0,0,2,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,43","35,7"
"strandbias, many samples",UPN2_111,20,31023234,G,A,missense_variant(MODERATE|MISSENSE|Gta/Ata|p.Val907Ile/c.2719G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),19011,254,19285,"0,0131708582",0,0,0,0,1,1,0,1,3,NO,0,NO,NO,O,NO,rs201990697,NO,"8,24E-006",NO,NO,"-0,38",Neutral,"0,019",Damaging,"35,42","35,75"
"inspected, many artifacts",UPN2_044,20,31023249,A,G,missense_variant(MODERATE|MISSENSE|Aaa/Gaa|p.Lys912Glu/c.2734A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3817,50,3882,"0,0128799588",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,79",Neutral,1,Tolerated,"35,3","35,4"
"low freq, many artifacts",UPN2_044,20,31023278,T,TG,frameshift_variant(HIGH||gtt/gGtt|p.Val922fs/c.2764dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|TG|INFO_REALIGN_3_PRIME),3830,68,3881,"0,0175212574",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,46",NA
"inspected, strandbias",UPN2_092,20,31023294,G,A,missense_variant(MODERATE|MISSENSE|Gga/Aga|p.Gly927Arg/c.2779G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),3564,39,3611,"0,0108003323",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,"0,174",Tolerated,"31,61","32,38"
"inspected, many artifacts",UPN2_041,20,31023303,T,C,missense_variant(MODERATE|MISSENSE|Tgg/Cgg|p.Trp930Arg/c.2788T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),2128,42,2183,"0,0192395786",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,84",Neutral,"0,098",Tolerated,"31,08","30,83"
"low bq, low freq, many artifacts",UPN2_074,20,31023303,T,G,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp930Gly/c.2788T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),6812,71,6929,"0,0102467889",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,8,Damaging,"29,92","15,1"
"inspected, many artifacts",UPN2_044,20,31023307,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu931Val/c.2792A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1967,32,2007,"0,0159441953",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,9",Neutral,"0,001",Damaging,"34,39","31,31"
"inspected, many artifacts",UPN2_044,20,31023310,A,G,missense_variant(MODERATE|MISSENSE|aAa/aGa|p.Lys932Arg/c.2795A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),1907,88,2007,"0,0438465371",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,81",Neutral,"0,336",Tolerated,"32,96","33,58"
"inspected, many artifacts",UPN2_091,20,31023315,G,A,missense_variant(MODERATE|MISSENSE|Gct/Act|p.Ala934Thr/c.2800G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),4700,52,4776,"0,0108877722",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,58",Neutral,"0,054",Tolerated,"34,84","32,44"
"low bq, low freq, many artifacts, many samples",UPN2_041,20,31023321,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr936Pro/c.2806A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),2137,22,2182,"0,0100824931",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,17,Damaging,"28,16","21,14"
"low bq, low freq, many artifacts, many samples",UPN2_042,20,31023321,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr936Pro/c.2806A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),15255,197,15579,"0,0126452275",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,17,Damaging,"28,54","16,32"
"low bq, low freq, many artifacts, many samples",UPN2_044,20,31023321,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr936Pro/c.2806A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1991,21,2021,"0,0103908956",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,17,Damaging,"28,45","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_045,20,31023321,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr936Pro/c.2806A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),12732,154,13004,"0,01184251",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,17,Damaging,"28,32","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_046,20,31023321,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr936Pro/c.2806A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),12044,132,12260,"0,010766721",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,17,Damaging,"28,32","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_048,20,31023321,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr936Pro/c.2806A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),5062,63,5156,"0,0122187742",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,17,Damaging,"28,36","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_049,20,31023321,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr936Pro/c.2806A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6421,69,6545,"0,0105423988",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,17,Damaging,"28,57","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_052,20,31023321,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr936Pro/c.2806A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),9344,105,9495,"0,0110584518",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,17,Damaging,"28,53","17,45"
"low bq, low freq, many artifacts, many samples",UPN2_053,20,31023321,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr936Pro/c.2806A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),15542,175,15829,"0,0110556573",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,17,Damaging,"28,52","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_056,20,31023321,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr936Pro/c.2806A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1914,32,1961,"0,016318205",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,17,Damaging,"28,17","16,34"
"low bq, low freq, many artifacts, many samples",UPN2_057,20,31023321,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr936Pro/c.2806A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),10471,123,10680,"0,0115168539",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,17,Damaging,"28,42","17,43"
"low bq, low freq, many artifacts, many samples",UPN2_059,20,31023321,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr936Pro/c.2806A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),11270,233,11573,"0,0201330683",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,17,Damaging,"28,99","15,37"
"low bq, low freq, many artifacts, many samples",UPN2_060,20,31023321,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr936Pro/c.2806A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),20231,388,20692,"0,0187512082",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,17,Damaging,"28,9","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_061,20,31023321,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr936Pro/c.2806A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),18252,407,18756,"0,0216997228",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,17,Damaging,"28,73","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_062,20,31023321,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr936Pro/c.2806A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),17886,382,18348,"0,0208197079",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,17,Damaging,"28,66","15,41"
"low bq, low freq, many artifacts, many samples",UPN2_063,20,31023321,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr936Pro/c.2806A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16649,368,17114,"0,0215028632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,17,Damaging,"28,91","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_064,20,31023321,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr936Pro/c.2806A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),10858,222,11117,"0,0199694162",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,17,Damaging,"28,84","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_065,20,31023321,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr936Pro/c.2806A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),10419,222,10700,"0,0207476636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,17,Damaging,"28,94","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_066,20,31023321,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr936Pro/c.2806A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),7133,114,7277,"0,0156657963",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,17,Damaging,"28,96","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_067,20,31023321,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr936Pro/c.2806A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),8228,152,8426,"0,0180394019",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,17,Damaging,"29,01","15,42"
"low bq, low freq, many artifacts, many samples",UPN2_068,20,31023321,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr936Pro/c.2806A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),11646,249,11941,"0,0208525249",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,17,Damaging,"28,77","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_069,20,31023321,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr936Pro/c.2806A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),19635,439,20171,"0,0217639185",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,17,Damaging,"28,83","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_070,20,31023321,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr936Pro/c.2806A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),11805,263,12117,"0,0217050425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,17,Damaging,"28,79","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_071,20,31023321,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr936Pro/c.2806A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),17027,349,17483,"0,019962249",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,17,Damaging,"28,82",15
"low bq, low freq, many artifacts, many samples",UPN2_072,20,31023321,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr936Pro/c.2806A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16992,365,17425,"0,0209469154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,17,Damaging,"28,83","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_073,20,31023321,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr936Pro/c.2806A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),13393,283,13734,"0,0206057958",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,17,Damaging,"28,91","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_074,20,31023321,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr936Pro/c.2806A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6762,132,6931,"0,0190448709",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,17,Damaging,"28,9","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_075,20,31023321,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr936Pro/c.2806A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),23658,436,24199,"0,0180172734",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,17,Damaging,"29,09","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_076,20,31023321,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr936Pro/c.2806A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),17055,377,17529,"0,0215072166",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,17,Damaging,"28,75","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_077,20,31023321,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr936Pro/c.2806A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),15217,304,15587,"0,0195034323",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,17,Damaging,"28,87","14,72"
"low bq, many samples",UPN2_078,20,31023321,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr936Pro/c.2806A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),18947,439,19476,"0,0225405627",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,17,Damaging,"28,81","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_079,20,31023321,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr936Pro/c.2806A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),12336,256,12662,"0,020217975",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,17,Damaging,"28,96","15,3"
"low bq, low freq, many artifacts, many samples",UPN2_080,20,31023321,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr936Pro/c.2806A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),20276,426,20821,"0,0204601124",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,17,Damaging,"28,82","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_081,20,31023321,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr936Pro/c.2806A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),19561,359,20020,"0,0179320679",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,17,Damaging,"28,86","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_082,20,31023321,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr936Pro/c.2806A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),13080,226,13374,"0,0168984597",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,17,Damaging,"28,86","14,54"
"low bq, many samples",UPN2_083,20,31023321,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr936Pro/c.2806A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),22081,509,22700,"0,0224229075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,17,Damaging,"28,76","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_084,20,31023321,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr936Pro/c.2806A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16046,353,16464,"0,0214407191",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,17,Damaging,"28,77","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_085,20,31023321,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr936Pro/c.2806A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),9723,199,9975,"0,0199498747",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,17,Damaging,"28,99","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_086,20,31023321,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr936Pro/c.2806A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6558,141,6728,"0,0209571938",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,17,Damaging,"28,64","14,8"
"low bq, many samples",UPN2_087,20,31023321,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr936Pro/c.2806A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16475,379,16944,"0,0223677998",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,17,Damaging,"28,92","15,32"
"low bq, low freq, many artifacts",UPN2_088,20,31023321,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr936Pro/c.2806A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),12885,249,13185,"0,0188850967",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,17,Damaging,"28,87","14,37"
"inspected, many artifacts",UPN2_006,20,31023327,C,T,missense_variant(MODERATE|MISSENSE|Cct/Tct|p.Pro938Ser/c.2812C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3133,93,3229,"0,0288014865",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,096",Tolerated,"31,14","31,73"
"low bq, low freq, many artifacts, many samples",UPN2_044,20,31023333,T,A,missense_variant(MODERATE|MISSENSE|Ttg/Atg|p.Leu940Met/c.2818T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),1991,21,2021,"0,0103908956",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,52",Neutral,125,Tolerated,"31,4","19,24"
"low bq, low freq, many artifacts, many samples",UPN2_048,20,31023333,T,A,missense_variant(MODERATE|MISSENSE|Ttg/Atg|p.Leu940Met/c.2818T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),5068,52,5153,"0,010091209",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,52",Neutral,125,Tolerated,"31,31","18,58"
"inspected, many artifacts",UPN2_006,20,31023337,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro941Leu/c.2822C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3197,53,3260,"0,0162576687",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,"0,366",Tolerated,"33,07","27,4"
"inspected, many artifacts",UPN2_044,20,31023343,AT,A,frameshift_variant(HIGH||ttg/|p.Leu944fs/c.2831delT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),1976,22,2022,"0,0108803165",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,35",NA
"low bq, low freq, many artifacts, many samples",UPN2_059,20,31023344,T,G,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp943Glu/c.2829T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),11382,116,11580,"0,0100172712",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,577,Tolerated,"29,63","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_061,20,31023344,T,G,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp943Glu/c.2829T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),18364,211,18762,"0,0112461358",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,577,Tolerated,"29,42","14,07"
"low bq, low freq, many artifacts, many samples",UPN2_062,20,31023344,T,G,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp943Glu/c.2829T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),17949,219,18350,"0,0119346049",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,577,Tolerated,"29,37","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_068,20,31023344,T,G,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp943Glu/c.2829T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),11695,143,11947,"0,0119695321",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,577,Tolerated,"29,46","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_069,20,31023344,T,G,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp943Glu/c.2829T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),19764,212,20172,"0,0105096173",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,577,Tolerated,"29,56","14,15"
"low bq, low freq, many artifacts, many samples",UPN2_070,20,31023344,T,G,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp943Glu/c.2829T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),11873,130,12115,"0,0107304994",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,577,Tolerated,"29,37","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_071,20,31023344,T,G,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp943Glu/c.2829T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),17138,177,17479,"0,0101264374",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,577,Tolerated,"29,63","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_072,20,31023344,T,G,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp943Glu/c.2829T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),17101,178,17422,"0,0102169671",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,577,Tolerated,"29,46","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_073,20,31023344,T,G,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp943Glu/c.2829T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),13475,155,13730,"0,0112891479",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,577,Tolerated,"29,64","14,08"
"low bq, low freq, many artifacts, many samples",UPN2_076,20,31023344,T,G,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp943Glu/c.2829T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),17170,211,17522,"0,0120420043",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,577,Tolerated,"29,28","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_077,20,31023344,T,G,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp943Glu/c.2829T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),15302,160,15587,"0,0102649644",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,577,Tolerated,"29,52","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_078,20,31023344,T,G,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp943Glu/c.2829T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),19097,216,19480,"0,0110882957",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,577,Tolerated,"29,42","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_079,20,31023344,T,G,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp943Glu/c.2829T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),12414,139,12676,"0,0109656043",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,577,Tolerated,"29,67","14,19"
"low bq, low freq, many artifacts, many samples",UPN2_083,20,31023344,T,G,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp943Glu/c.2829T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),22263,237,22709,"0,0104363909",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,577,Tolerated,"29,44","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_084,20,31023344,T,G,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp943Glu/c.2829T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),16105,203,16459,"0,0123336776",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,577,Tolerated,"29,45","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_085,20,31023344,T,G,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp943Glu/c.2829T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9801,111,9980,"0,0111222445",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,577,Tolerated,"29,5","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_087,20,31023344,T,G,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp943Glu/c.2829T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),16629,186,16963,"0,0109650416",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,577,Tolerated,"29,59","14,33"
"low bq, low freq, many artifacts",UPN2_088,20,31023344,T,G,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp943Glu/c.2829T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),12930,139,13187,"0,010540684",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,577,Tolerated,"29,68",14
"low bq, low freq, many artifacts, many samples",UPN2_089,20,31023348,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr945Pro/c.2833A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),10617,138,10791,"0,0127884348",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,167,Tolerated,"28,77","15,87"
"low bq, many samples",UPN2_059,20,31023348,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr945Pro/c.2833A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),11226,300,11573,"0,0259224056",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,167,Tolerated,"28,04","15,08"
"low bq, many samples",UPN2_060,20,31023348,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr945Pro/c.2833A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),20024,536,20682,"0,0259162557",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,167,Tolerated,"28,02","14,48"
"low bq, many samples",UPN2_061,20,31023348,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr945Pro/c.2833A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),18059,562,18756,"0,0299637449",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,167,Tolerated,"27,92","14,38"
"low bq, many samples",UPN2_062,20,31023348,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr945Pro/c.2833A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),17647,569,18337,"0,0310301576",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,167,Tolerated,"27,89","14,44"
"low bq, many samples",UPN2_063,20,31023348,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr945Pro/c.2833A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16488,494,17110,"0,0288720047",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,167,Tolerated,"27,97","14,6"
"low bq, many samples",UPN2_064,20,31023348,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr945Pro/c.2833A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),10704,323,11111,"0,0290702907",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,167,Tolerated,"28,09","14,3"
"low bq, many samples",UPN2_065,20,31023348,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr945Pro/c.2833A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),10293,329,10697,"0,0307562868",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,167,Tolerated,"28,14","14,48"
"low bq, many samples",UPN2_066,20,31023348,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr945Pro/c.2833A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),7052,190,7278,"0,0261060731",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,167,Tolerated,"27,84","14,56"
"low bq, many samples",UPN2_067,20,31023348,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr945Pro/c.2833A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),8150,217,8416,"0,0257842205",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,167,Tolerated,"28,23","14,4"
"low bq, many samples",UPN2_068,20,31023348,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr945Pro/c.2833A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),11502,376,11941,"0,0314881501",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,167,Tolerated,"27,92","14,5"
"low bq, many samples",UPN2_069,20,31023348,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr945Pro/c.2833A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),19421,616,20158,"0,0305585872",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,167,Tolerated,"27,95","14,5"
"low bq, many samples",UPN2_070,20,31023348,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr945Pro/c.2833A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),11634,423,12105,"0,0349442379",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,167,Tolerated,"28,02","14,68"
"low bq, many samples",UPN2_071,20,31023348,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr945Pro/c.2833A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16828,525,17475,"0,0300429185",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,167,Tolerated,"28,09","14,55"
"low bq, many samples",UPN2_072,20,31023348,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr945Pro/c.2833A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16824,499,17415,"0,0286534597",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,167,Tolerated,"27,98","14,56"
"low bq, many samples",UPN2_073,20,31023348,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr945Pro/c.2833A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),13236,406,13718,"0,029596151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,167,Tolerated,"28,1","14,87"
"low bq, many samples",UPN2_074,20,31023348,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr945Pro/c.2833A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6732,164,6929,"0,0236686391",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,167,Tolerated,"28,08","14,2"
"low bq, many samples",UPN2_075,20,31023348,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr945Pro/c.2833A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),23379,649,24191,"0,0268281592",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,167,Tolerated,"28,22","14,36"
"low bq, many samples",UPN2_076,20,31023348,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr945Pro/c.2833A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16868,516,17513,"0,0294638269",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,167,Tolerated,"27,92","14,58"
"low bq, many samples",UPN2_077,20,31023348,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr945Pro/c.2833A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),15028,465,15576,"0,029853621",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,167,Tolerated,"27,96","14,5"
"low bq, many samples",UPN2_078,20,31023348,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr945Pro/c.2833A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),18777,580,19469,"0,0297909497",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,167,Tolerated,"27,96","14,59"
"low bq, many samples",UPN2_079,20,31023348,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr945Pro/c.2833A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),12209,401,12671,"0,0316470681",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,167,Tolerated,"28,11","14,63"
"low bq, many samples",UPN2_080,20,31023348,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr945Pro/c.2833A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),20061,586,20798,"0,0281757861",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,167,Tolerated,"27,97","14,88"
"low bq, many samples",UPN2_081,20,31023348,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr945Pro/c.2833A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),19309,614,20012,"0,030681591",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,167,Tolerated,"28,1","14,34"
"low bq, many samples",UPN2_082,20,31023348,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr945Pro/c.2833A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),12938,356,13378,"0,0266108536",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,167,Tolerated,"27,96","14,62"
"low bq, many samples",UPN2_083,20,31023348,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr945Pro/c.2833A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),21867,692,22695,"0,0304912976",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,167,Tolerated,"27,89","14,58"
"low bq, many samples",UPN2_084,20,31023348,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr945Pro/c.2833A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),15878,477,16449,"0,0289987233",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,167,Tolerated,"27,96","14,49"
"low bq, many samples",UPN2_085,20,31023348,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr945Pro/c.2833A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),9609,307,9978,"0,0307676889",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,167,Tolerated,"27,98","14,47"
"low bq, many samples",UPN2_086,20,31023348,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr945Pro/c.2833A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6492,181,6721,"0,0269305163",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,167,Tolerated,"27,92","14,33"
"low bq, many samples",UPN2_087,20,31023348,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr945Pro/c.2833A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16312,535,16948,"0,0315671466",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,167,Tolerated,"28,06","14,48"
"low bq, many samples",UPN2_088,20,31023348,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr945Pro/c.2833A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),12742,379,13182,"0,0287513276",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,167,Tolerated,"28,17","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_103,20,31023348,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr945Pro/c.2833A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),10063,105,10206,"0,0102880658",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,167,Tolerated,"28,49","14,07"
"low bq, low freq, many artifacts, many samples",UPN2_108,20,31023348,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr945Pro/c.2833A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),15820,161,16034,"0,0100411625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,167,Tolerated,"28,81","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_109,20,31023348,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr945Pro/c.2833A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),14378,163,14596,"0,0111674431",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,167,Tolerated,"28,61","14,54"
"low bq, low freq, many artifacts",UPN2_111,20,31023348,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr945Pro/c.2833A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),11410,133,11601,"0,0114645289",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,167,Tolerated,"28,61","14,71"
"inspected, many artifacts",UPN2_048,20,31023348,A,G,missense_variant(MODERATE|MISSENSE|Aca/Gca|p.Thr945Ala/c.2833A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),4993,121,5164,"0,0234314485",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,04",Neutral,"0,38",Tolerated,"28,14","32,4"
"inspected, many artifacts",UPN2_052,20,31023348,A,G,missense_variant(MODERATE|MISSENSE|Aca/Gca|p.Thr945Ala/c.2833A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9309,118,9507,"0,012411907",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,04",Neutral,"0,38",Tolerated,"28,3","33,47"
"inspected, many artifacts",UPN2_044,20,31023348,A,T,missense_variant(MODERATE|MISSENSE|Aca/Tca|p.Thr945Ser/c.2833A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1965,28,2021,"0,0138545275",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,54",Neutral,"0,036",Damaging,"28,4","27,68"
"low freq, many artifacts",UPN2_044,20,31023406,C,T,missense_variant(MODERATE|MISSENSE|tCt/tTt|p.Ser964Phe/c.2891C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5386,61,5458,"0,011176255",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-2,33",Neutral,23,Damaging,"35,32","33,38"
"inspected, many artifacts",UPN2_004,20,31023411,G,A,missense_variant(MODERATE|MISSENSE|Gga/Aga|p.Gly966Arg/c.2896G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),1171,21,1193,"0,0176026823",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,74",Neutral,"0,001",Damaging,"35,47","34,95"
"low freq, many artifacts",UPN2_006,20,31023418,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser968Asn/c.2903G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),5225,59,5285,"0,0111636708",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,85,Tolerated,"35,49","35,63"
"inspected, many artifacts",UPN2_056,20,31023419,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser968Arg/c.2904T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),3684,47,3753,"0,0125233147",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,13",Neutral,"0,044",Damaging,"34,72","29,72"
"inspected, many artifacts",UPN2_044,20,31023433,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser973Asn/c.2918G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),9821,108,9943,"0,0108619129",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-0,5",Neutral,"0,068",Tolerated,"34,12","34,37"
"low freq, many artifacts, many samples",UPN2_071,20,31023436,A,C,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr974Ser/c.2921A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),26170,316,26605,"0,0118774666",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,"0,41",Tolerated,"33,42","31,54"
"low freq, many artifacts, many samples",UPN2_072,20,31023436,A,C,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr974Ser/c.2921A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),26556,290,26955,"0,0107586719",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,"0,41",Tolerated,"33,4","31,57"
"inspected, many artifacts",UPN2_006,20,31023441,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln976Lys/c.2926C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),7228,134,7381,"0,0181547216",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,922",Tolerated,"35,09","34,92"
"inspected, many artifacts",UPN2_044,20,31023442,A,G,missense_variant(MODERATE|MISSENSE|cAa/cGa|p.Gln976Arg/c.2927A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),8758,152,8932,"0,0170174653",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,9",Neutral,"0,366",Tolerated,"34,06","32,6"
"inspected, many artifacts",UPN2_009,20,31023444,C,T,stop_gained(HIGH|NONSENSE|Cag/Tag|p.Gln977*/c.2929C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),47786,707,48594,"0,0145491213",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,74","34,6"
"inspected, many artifacts",UPN2_048,20,31023448,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val978Glu/c.2933T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),14547,188,14828,"0,0126787159",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,98",Neutral,"0,002",Damaging,"31,44","29,69"
"inspected, many artifacts",UPN2_006,20,31023456,G,A,missense_variant(MODERATE|MISSENSE|Gaa/Aaa|p.Glu981Lys/c.2941G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),7277,101,7384,"0,0136782232",0,0,0,0,0,1,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-1,16",Neutral,"0,004",Damaging,"34,59","34,01"
"inspected, many artifacts",UPN2_006,20,31023456,GA,G,frameshift_variant(HIGH||aag/|p.Lys982fs/c.2945delA|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G|INFO_REALIGN_3_PRIME),7261,83,7384,"0,01124052",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,15",NA
"many artifacts, many samples",UPN2_014,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),23243,263,23558,"0,0111639358",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"33,29","33,9"
"many artifacts, many samples",UPN2_015,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),31195,330,31594,"0,0104450212",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"33,26","33,88"
"many artifacts, many samples",UPN2_017,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),10385,142,10550,"0,0134597156",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"33,27","34,8"
"many artifacts, many samples",UPN2_021,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),17249,182,17462,"0,010422632",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"33,37","33,75"
"many artifacts, many samples",UPN2_023,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),25534,267,25856,"0,0103264233",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"33,35","34,3"
"many artifacts, many samples",UPN2_024,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),12175,134,12336,"0,0108625162",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"33,25","34,13"
"many artifacts, many samples",UPN2_025,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),27154,311,27521,"0,0113004615",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"33,41","33,79"
"many artifacts, many samples",UPN2_004,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),1566,27,1594,"0,0169385194",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"32,96","31,78"
"many artifacts, many samples",UPN2_027,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),31312,321,31708,"0,0101236281",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"33,26","33,68"
"many artifacts, many samples",UPN2_089,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),20293,212,20528,"0,0103273578",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"34,36","34,11"
"many artifacts, many samples",UPN2_042,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),35002,425,35519,"0,011965427",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"33,42","34,2"
"many artifacts, many samples",UPN2_043,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),26677,382,27145,"0,0140725732",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"33,55","34,05"
"many artifacts, many samples",UPN2_029,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),27433,290,27796,"0,0104331558",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"33,28","34,2"
"many artifacts, many samples",UPN2_030,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),25028,267,25351,"0,0105321289",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"33,29","34,15"
"many artifacts, many samples",UPN2_005,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),5950,75,6036,"0,0124254473",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"33,15","34,24"
"many artifacts, many samples",UPN2_045,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),36933,489,37516,"0,0130344386",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"33,42","33,93"
"many artifacts, many samples",UPN2_046,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),32368,360,32817,"0,0109699241",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"33,39","33,04"
"many artifacts, many samples",UPN2_047,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),39254,457,39830,"0,0114737635",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"33,45","33,12"
"many artifacts, many samples",UPN2_048,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),14588,202,14827,"0,0136237944",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"33,39","33,42"
"many artifacts, many samples",UPN2_036,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),22520,251,22815,"0,0110015341",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"33,39","33,9"
"many artifacts, many samples",UPN2_006,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),7276,86,7384,"0,0116468039",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"33,08","33,4"
"many artifacts, many samples",UPN2_049,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),19921,227,20179,"0,0112493186",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"33,42","33,44"
"many artifacts, many samples",UPN2_050,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),31900,443,32425,"0,0136622976",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"33,46","33,55"
"many artifacts, many samples",UPN2_039,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),19368,214,19630,"0,0109016811",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"33,24","34,61"
"many artifacts, many samples",UPN2_053,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),36194,457,36749,"0,0124357125",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"33,33","33,58"
"many artifacts, many samples",UPN2_054,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),23260,310,23636,"0,0131155864",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"33,3","33,4"
"many artifacts, many samples",UPN2_055,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),38327,437,38865,"0,0112440499",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"33,41","33,57"
"many artifacts, many samples",UPN2_056,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),5511,78,5595,"0,0139410188",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"33,52","32,58"
"many artifacts, many samples",UPN2_057,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),30166,357,30623,"0,0116579042",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"33,47","33,5"
"many artifacts, many samples",UPN2_058,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),32791,407,33271,"0,0122328755",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"33,59","33,38"
"many artifacts, many samples",UPN2_012,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),20119,231,20403,"0,0113218644",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"33,18","33,81"
"many artifacts, many samples",UPN2_060,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),23844,248,24179,"0,0102568344",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"32,88","33,63"
"many artifacts, many samples",UPN2_040,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),14778,163,14984,"0,0108782702",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"33,28","33,48"
"inspected, many artifacts, many samples",UPN2_092,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),11772,124,11911,"0,0104105449",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"34,45","33,9"
"many artifacts, many samples",UPN2_077,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),34525,359,34978,"0,0102635943",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"32,7","33,38"
"many artifacts, many samples",UPN2_081,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),25509,284,25872,"0,0109771181",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"32,86","33,35"
"many artifacts, many samples",UPN2_082,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),36016,393,36530,"0,0107582809",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"32,89",33
"many artifacts, many samples",UPN2_084,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),29267,300,29653,"0,0101170202",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"32,67","33,29"
"many artifacts, many samples",UPN2_096,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),20511,218,20755,"0,0105034931",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"34,43","33,7"
"many artifacts, many samples",UPN2_098,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),17217,180,17418,"0,0103341371",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"34,45","33,63"
"many artifacts, many samples",UPN2_101,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),18883,203,19112,"0,010621599",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"34,3","33,97"
"many artifacts, many samples",UPN2_105,20,31023460,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys982Arg/c.2945A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),20684,226,20940,"0,0107927412",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,24",Neutral,"0,499",Tolerated,"34,45","33,54"
"low freq, many artifacts",UPN2_006,20,31023471,A,G,missense_variant(MODERATE|MISSENSE|Aac/Gac|p.Asn986Asp/c.2956A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),7236,137,7383,"0,0185561425",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,24",Neutral,"0,008",Damaging,"33,58","34,46"
"low freq, many artifacts",UPN2_056,20,31023473,C,G,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn986Lys/c.2958C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),5512,79,5594,"0,0141222739",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,"0,069",Tolerated,"34,62","33,56"
"low freq, many artifacts",UPN2_006,20,31023475,GA,G,frameshift_variant(HIGH||gga/|p.Asp988fs/c.2961delA|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),7250,97,7382,"0,0131400704",0,0,0,1,1,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,85",NA
"low freq, many artifacts",UPN2_006,20,31023490,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu992Gln/c.2975T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),7250,79,7375,"0,0107118644",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,"0,279",Tolerated,"34,16","29,35"
"low freq, many artifacts",UPN2_041,20,31023498,C,T,missense_variant(MODERATE|MISSENSE|Cac/Tac|p.His995Tyr/c.2983C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),2998,42,3047,"0,0137840499",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,83",Deleterious,"0,002",Damaging,"32,87","31,86"
"low freq, many artifacts, many samples",UPN2_006,20,31023507,T,TC,frameshift_variant(HIGH||acg/Cacg|p.Thr999fs/c.2994dupC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|TC|INFO_REALIGN_3_PRIME),6309,72,6339,"0,0113582584",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,71",NA
"low freq, many artifacts",UPN2_006,20,31023550,A,G,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp1012Gly/c.3035A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),6246,76,6339,"0,0119892728",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,68",Deleterious,"0,001",Damaging,"35,56","35,83"
"low bq, low freq, many artifacts, many samples",UPN2_001,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16307,178,16495,"0,0107911488",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,37","15,08"
"low bq, many samples",UPN2_041,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),50443,1184,51710,"0,0228969252",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,66","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_004,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4005,51,4058,"0,0125677674",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,21","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_089,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),24251,388,24667,"0,0157295172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,18","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_042,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),48827,821,49737,"0,0165068259",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,42","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_043,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),32893,502,33451,"0,0150070252",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,68","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_044,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),8601,104,8720,"0,0119266055",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,12","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_045,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),47360,680,48119,"0,014131632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,61","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_046,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),40686,556,41301,"0,0134621438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,66","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_047,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),57683,895,58671,"0,0152545551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,28","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_048,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),45329,984,46390,"0,021211468",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,39","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_006,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),8800,96,8907,"0,0107780397",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,38","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_049,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),27397,448,27890,"0,0160631051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,48","15,88"
"low bq, low freq, many artifacts, many samples",UPN2_050,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),38210,590,38853,"0,0151854426",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,78","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_051,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),29753,423,30208,"0,0140029131",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,71","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_052,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),36383,520,36957,"0,0140704061",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,62","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_053,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),43755,620,44495,"0,0139341499",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,65","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_054,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),29911,457,30417,"0,0150244929",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,4","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_007,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),46251,531,46832,"0,0113384011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,44","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_008,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),68927,710,69714,"0,010184468",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,5","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_009,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),54085,576,54694,"0,0105313197",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,48","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_010,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),35919,408,36354,"0,0112229741",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,48","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_011,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),43886,456,44394,"0,0102716583",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,39","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_055,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),48698,747,49532,"0,0150811597",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,52","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_056,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),8581,141,8732,"0,0161475034",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,24","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_090,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20462,393,20873,"0,0188281512",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,28","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_057,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),39379,647,40082,"0,0161419091",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,6","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_058,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),37029,561,37645,"0,0149023775",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,84","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_059,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),34067,587,34707,"0,0169130147",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,4","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_012,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22641,245,22906,"0,0106958875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,49","16,2"
"low bq, low freq, many artifacts, many samples",UPN2_060,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),36259,663,36953,"0,0179417097",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,3","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_013,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),12638,135,12786,"0,0105584233",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,52","14,1"
"low bq, low freq, many artifacts, many samples",UPN2_091,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15442,251,15703,"0,0159842068",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,19","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_092,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),13465,263,13753,"0,0191231004",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,38","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_093,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),14703,260,14981,"0,0173553167",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,31","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_061,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),36071,601,36720,"0,0163671024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,39","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_062,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),31247,529,31806,"0,016632082",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,41","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_063,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),36154,588,36807,"0,0159752221",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,45","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_064,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),31143,502,31701,"0,0158354626",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,33","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_065,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),31490,451,31980,"0,0141025641",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,37","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_066,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),37819,537,38399,"0,0139847392",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,89","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_067,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),39035,537,39619,"0,0135541028",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,95","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_068,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),35211,495,35764,"0,0138407337",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,54","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_069,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),46326,802,47245,"0,0169753413",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,3","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_070,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),29185,450,29689,"0,0151571289",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,36","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_071,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),24386,403,24821,"0,0162362516",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,39","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_072,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),27135,461,27638,"0,0166799334",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,3","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_073,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),29051,563,29655,"0,0189849941",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,26","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_074,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),24043,370,24445,"0,0151360196",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,62","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_075,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),43612,736,44416,"0,0165706052",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,41","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_076,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),35720,585,36351,"0,0160930923",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,35","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_077,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),43960,688,44696,"0,0153928763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,52","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_078,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),38205,602,38863,"0,0154903121",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,29","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_079,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),24495,401,24928,"0,0160863286",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,31","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_080,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),40184,631,40880,"0,0154354207",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,26","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_081,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),40537,702,41294,"0,0170000484",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,26","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_082,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),40165,623,40835,"0,0152565201",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,76","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_083,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),44791,751,45610,"0,0164656873",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,29","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_084,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),38953,596,39588,"0,0150550672",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,43","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_085,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),33911,422,34387,"0,0122720796",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,91","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_086,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),25359,306,25692,"0,0119103223",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,14","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_087,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),47812,820,48713,"0,0168332889",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,5","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_088,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),34819,586,35456,"0,0165275271",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,45","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_094,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),27276,455,27750,"0,0163963964",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,21","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_095,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22588,351,22969,"0,0152814663",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,16","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_096,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),25016,437,25477,"0,017152726",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,1","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_097,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),28460,508,28991,"0,0175226795",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,18","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_098,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21815,374,22215,"0,0168354715",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,02","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_099,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),12847,263,13130,"0,0200304646",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,11","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_100,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21182,384,21595,"0,017781894",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,22","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_101,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21686,316,22044,"0,0143349664",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,18","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_102,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),23716,369,24133,"0,0152902664",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,19","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_103,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20732,308,21074,"0,0146151656",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,2","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_104,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),26888,441,27367,"0,0161142982",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,13","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_105,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),24352,390,24775,"0,0157416751",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,17","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_106,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),32398,581,33009,"0,0176012603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,99","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_107,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),37350,699,38104,"0,0183445308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,28","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_108,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),33460,559,34078,"0,0164035448",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,33","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_109,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),31829,486,32369,"0,0150143656",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,21","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_110,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),34494,567,35114,"0,0161474056",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,21","14,89"
"low bq, low freq, many artifacts",UPN2_111,20,31023573,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu1020*/c.3058G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),28812,495,29353,"0,0168636937",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,24","14,6"
"low bq, low freq, many artifacts",UPN2_044,20,31023588,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys1025*/c.3073A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4249,44,4306,"0,0102183",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,76","21,77"
"low bq, low freq, many artifacts, many samples",UPN2_059,20,31023617,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys1034Asn/c.3102A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),22205,464,22826,"0,0203276965",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Damaging,"27,79","14,35"
"low bq, many samples",UPN2_060,20,31023617,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys1034Asn/c.3102A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),24285,558,25021,"0,0223012669",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Damaging,"27,78","14,62"
"low bq, many samples",UPN2_061,20,31023617,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys1034Asn/c.3102A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),23336,607,24097,"0,0251898577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Damaging,"27,51","15,01"
"low bq, many samples",UPN2_062,20,31023617,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys1034Asn/c.3102A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),20225,534,20885,"0,0255685899",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Damaging,"27,52","14,66"
"low bq, many samples",UPN2_063,20,31023617,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys1034Asn/c.3102A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),22941,526,23622,"0,0222673779",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Damaging,"27,66","14,61"
"low bq, many samples",UPN2_064,20,31023617,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys1034Asn/c.3102A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),20667,512,21326,"0,0240082528",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Damaging,"27,69","14,52"
"low bq, many samples",UPN2_065,20,31023617,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys1034Asn/c.3102A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),19811,477,20408,"0,023373187",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Damaging,"27,7","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_066,20,31023617,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys1034Asn/c.3102A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),18881,428,19466,"0,0219870544",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Damaging,"27,84","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_067,20,31023617,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys1034Asn/c.3102A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),18419,392,18936,"0,0207013097",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Damaging,"27,86","14,48"
"low bq, many samples",UPN2_068,20,31023617,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys1034Asn/c.3102A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),20227,533,20889,"0,0255158217",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Damaging,"27,37","14,72"
"low bq, many samples",UPN2_069,20,31023617,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys1034Asn/c.3102A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),29702,740,30667,"0,0241301725",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Damaging,"27,63","14,96"
"low bq, many samples",UPN2_070,20,31023617,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys1034Asn/c.3102A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),18158,484,18770,"0,0257858284",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Damaging,"27,35","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_071,20,31023617,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys1034Asn/c.3102A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),15429,349,15885,"0,0219704123",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Damaging,"27,55","14,64"
"low bq, many samples",UPN2_072,20,31023617,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys1034Asn/c.3102A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),17898,442,18480,"0,0239177489",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Damaging,"27,6","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_073,20,31023617,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys1034Asn/c.3102A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),19933,449,20550,"0,0218491484",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Damaging,"27,65","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_074,20,31023617,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys1034Asn/c.3102A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),13705,281,14083,"0,019953135",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Damaging,"27,73","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_075,20,31023617,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys1034Asn/c.3102A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),27803,594,28591,"0,0207757686",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Damaging,"27,95","14,7"
"low bq, many samples",UPN2_076,20,31023617,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys1034Asn/c.3102A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),22515,580,23224,"0,0249741647",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Damaging,"27,39","14,54"
"low bq, many samples",UPN2_077,20,31023617,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys1034Asn/c.3102A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),26615,624,27418,"0,0227587716",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Damaging,"27,52","14,7"
"low bq, many samples",UPN2_078,20,31023617,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys1034Asn/c.3102A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),24571,603,25328,"0,0238076437",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Damaging,"27,43","14,46"
"low bq, many samples",UPN2_079,20,31023617,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys1034Asn/c.3102A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),15788,366,16262,"0,0225064568",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Damaging,"27,67","14,55"
"low bq, many samples",UPN2_080,20,31023617,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys1034Asn/c.3102A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),26357,644,27196,"0,0236799529",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Damaging,"27,63","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_081,20,31023617,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys1034Asn/c.3102A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),27645,610,28445,"0,0214448937",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Damaging,"27,83","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_082,20,31023617,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys1034Asn/c.3102A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),21943,486,22587,"0,0215168017",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Damaging,"27,91","14,91"
"low bq, many samples",UPN2_083,20,31023617,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys1034Asn/c.3102A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),29584,805,30585,"0,0263200915",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Damaging,"27,49","15,16"
"low bq, many samples",UPN2_084,20,31023617,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys1034Asn/c.3102A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),24078,613,24810,"0,0247077791",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Damaging,"27,52","14,57"
"low bq, many samples",UPN2_085,20,31023617,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys1034Asn/c.3102A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16624,407,17147,"0,0237359305",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Damaging,"27,6","14,46"
"low bq, many samples",UPN2_086,20,31023617,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys1034Asn/c.3102A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),11187,284,11550,"0,0245887446",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Damaging,"27,56","14,34"
"low bq, many samples",UPN2_087,20,31023617,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys1034Asn/c.3102A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),29161,674,30037,"0,0224389919",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Damaging,"27,77","14,38"
"low bq, low freq, many artifacts",UPN2_088,20,31023617,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys1034Asn/c.3102A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),21916,460,22554,"0,0203954953",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,1,Damaging,"27,93","14,72"
"low freq, many artifacts",UPN2_044,20,31023617,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys1034Asn/c.3102A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4231,58,4311,"0,013453955",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,"8,24E-006",NO,NO,"-1,35",Neutral,"0,001",Damaging,"29,75","30,95"
"low freq, many artifacts",UPN2_044,20,31023621,A,T,missense_variant(MODERATE|MISSENSE|Aat/Tat|p.Asn1036Tyr/c.3106A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4240,57,4312,"0,0132189239",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,014",Damaging,"34,18","30,26"
"low bq, low freq, many artifacts",UPN2_056,20,31023621,A,T,missense_variant(MODERATE|MISSENSE|Aat/Tat|p.Asn1036Tyr/c.3106A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5982,81,6072,"0,0133399209",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,014",Damaging,"34,16","26,52"
"low bq, low freq, many artifacts, many samples",UPN2_072,20,31023628,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn1038Thr/c.3113A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),18187,193,18482,"0,0104425928",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,4,Damaging,"28,37","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_076,20,31023628,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn1038Thr/c.3113A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),22825,254,23228,"0,0109350784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,4,Damaging,"28,25","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_077,20,31023628,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn1038Thr/c.3113A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),26951,278,27420,"0,010138585",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,26",Neutral,4,Damaging,"28,41","15,19"
"many samples, low freq, neutral effect",UPN2_001,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),16250,692,17017,"0,0406652171",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"32,91","31,45"
"many samples, low freq, neutral effect",UPN2_014,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),32065,957,33144,"0,0288740043",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"32,07","31,34"
"many samples, low freq, neutral effect",UPN2_015,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),38812,896,39877,"0,0224690925",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"32,14","31,47"
"many samples, low freq, neutral effect",UPN2_016,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),20135,499,20748,"0,0240505109",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"32,05","31,13"
"many samples, low freq, neutral effect",UPN2_017,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),14358,417,14838,"0,028103518",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"32,22","31,51"
"many samples, low freq, neutral effect",UPN2_018,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),20756,543,21386,"0,0253904423",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"32,17","31,29"
"many samples, low freq, neutral effect",UPN2_019,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),24022,698,24796,"0,0281497016",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"32,19","31,47"
"many samples, low freq, neutral effect",UPN2_020,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),21610,674,22393,"0,0300986916",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"32,13","31,44"
"many samples, low freq, neutral effect",UPN2_021,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),22566,713,23369,"0,0305105054",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"32,15","31,37"
"many samples, low freq, neutral effect",UPN2_002,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),20742,1038,21844,"0,0475187695",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"32,93","31,34"
"many samples, low freq, neutral effect",UPN2_003,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3994,142,4151,"0,0342086244",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"32,85","31,32"
"many samples, low freq, neutral effect",UPN2_022,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),30773,776,31655,"0,0245142947",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"32,09","31,29"
"many samples, low freq, neutral effect",UPN2_023,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),34263,964,35378,"0,0272485726",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"32,07","31,7"
"many samples, low freq, neutral effect",UPN2_024,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),15345,341,15757,"0,0216411754",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"32,11","31,25"
"many samples, low freq, neutral effect",UPN2_025,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),35387,899,36428,"0,0246788185",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"32,07","31,31"
"many samples, low freq, neutral effect",UPN2_026,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),37448,1010,38637,"0,0261407459",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"32,19","31,39"
many samples,UPN2_004,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),4364,123,4501,"0,0273272606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,64,Tolerated,"33,25","31,15"
many samples,UPN2_027,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),39200,1286,40678,"0,0316141403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,64,Tolerated,"32,11","31,49"
"many samples, low freq, neutral effect",UPN2_042,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),51861,593,52820,"0,011226808",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"31,93","30,92"
"many samples, low freq, neutral effect",UPN2_028,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),28790,847,29756,"0,0284648474",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"32,19","31,45"
"many samples, low freq, neutral effect",UPN2_043,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),33220,450,33870,"0,0132860939",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"31,93","31,01"
"low freq, many artifacts, many samples",UPN2_044,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),8700,174,8897,"0,0195571541",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,64,Tolerated,"32,05","31,27"
"many samples, low freq, neutral effect",UPN2_029,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),36864,1111,38141,"0,0291287591",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"32,11","31,32"
"many samples, low freq, neutral effect",UPN2_030,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),31365,952,32450,"0,0293374422",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"32,17","31,59"
many samples,UPN2_031,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),21256,485,21814,"0,0222334281",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,64,Tolerated,"32,09","31,53"
"many samples, low freq, neutral effect",UPN2_005,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),6807,370,7203,"0,0513674858",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"32,87","31,62"
many samples,UPN2_032,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),11838,321,12202,"0,0263071628",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,64,Tolerated,"32,04","31,56"
"many samples, low freq, neutral effect",UPN2_046,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),41745,869,42805,"0,0203013667",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"32,04","31,27"
"many samples, low freq, neutral effect",UPN2_033,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),25306,632,26064,"0,0242480049",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"32,07","31,27"
many samples,UPN2_034,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9860,245,10157,"0,0241212957",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,64,Tolerated,"32,17","31,4"
"many samples, low freq, neutral effect",UPN2_047,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),62392,917,63700,"0,0143956044",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"31,97","30,87"
"many samples, low freq, neutral effect",UPN2_048,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),60130,970,61441,"0,0157875035",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"32,03","31,18"
"many samples, low freq, neutral effect",UPN2_035,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),28471,954,29517,"0,0323203578",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"32,1","31,47"
"many samples, low freq, neutral effect",UPN2_036,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),27597,903,28639,"0,0315304305",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"32,04","31,53"
"many samples, low freq, neutral effect",UPN2_006,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),10105,615,10744,"0,0572412509",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"32,8","31,46"
"many samples, low freq, neutral effect",UPN2_049,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),29387,403,30074,"0,0134002793",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"31,97","31,5"
"many samples, low freq, neutral effect",UPN2_037,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),52620,1461,54323,"0,0268946855",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"32,17","31,56"
"many samples, low freq, neutral effect",UPN2_051,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),31168,343,31684,"0,0108256533",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"31,92","30,9"
"many samples, low freq, neutral effect",UPN2_038,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),56737,1701,58732,"0,028962065",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"32,14","31,45"
"many samples, low freq, neutral effect",UPN2_039,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),25671,801,26592,"0,0301218412",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"32,18","31,55"
"many samples, low freq, neutral effect",UPN2_053,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),44760,661,45638,"0,0144835444",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"32,02","31,25"
"many samples, low freq, neutral effect",UPN2_007,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),47145,1895,49200,"0,0385162602",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"32,84","31,37"
"many samples, low freq, neutral effect",UPN2_008,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),67706,2449,70411,"0,0347814972",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"32,96","31,4"
"many samples, low freq, neutral effect",UPN2_009,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),52864,1646,54738,"0,0300705177",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"32,91","31,32"
"many samples, low freq, neutral effect",UPN2_010,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),36345,1542,37989,"0,0405906973",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"32,85","31,56"
"many samples, low freq, neutral effect",UPN2_011,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),44741,1828,46721,"0,0391258749",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"32,88","31,41"
"many samples, low freq, neutral effect",UPN2_055,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),49774,594,50638,"0,0117303211",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"31,99","31,13"
"low freq, many artifacts, many samples",UPN2_056,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),10151,129,10317,"0,0125036348",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,64,Tolerated,"32,05","31,29"
"many samples, low freq, neutral effect",UPN2_057,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),41282,690,42216,"0,0163445139",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"31,93","31,34"
"many samples, low freq, neutral effect",UPN2_058,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),37883,993,39090,"0,0254029163",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"31,91","30,92"
"many samples, low freq, neutral effect",UPN2_059,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),40968,1353,42545,"0,0318016218",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"31,7","31,27"
"many samples, low freq, neutral effect",UPN2_012,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),22829,1010,23927,"0,0422117273",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"32,82","31,38"
"many samples, low freq, neutral effect",UPN2_060,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),35540,983,36731,"0,0267621355",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"31,67","31,03"
many samples,UPN2_040,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),20855,653,21577,"0,0302637067",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,64,Tolerated,"32,16","31,49"
many samples,UPN2_013,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),12968,527,13541,"0,0389188391",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,64,Tolerated,"32,77","31,7"
"many samples, low freq, neutral effect",UPN2_061,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),34471,1115,35713,"0,031221124",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"31,75","31,14"
"many samples, low freq, neutral effect",UPN2_062,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),30416,1117,31665,"0,0352755408",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"31,8","31,38"
"inspected, low freq, neutral effect",UPN2_063,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),34095,1232,35550,"0,0346554149",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,64,Tolerated,"31,74","31,13"
"many samples, low freq, neutral effect",UPN2_064,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),33345,1365,34844,"0,0391746068",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"31,71","31,26"
"many samples, low freq, neutral effect",UPN2_065,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),34275,1131,35549,"0,0318152409",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"31,65","31,05"
"many samples, low freq, neutral effect",UPN2_066,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),36119,1413,37677,"0,0375029859",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"31,66","31,26"
"many samples, low freq, neutral effect",UPN2_067,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),33100,1160,34409,"0,0337121102",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"31,58","31,26"
"many samples, low freq, neutral effect",UPN2_068,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),32671,1040,33846,"0,0307274124",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"31,76","31,36"
"many samples, low freq, neutral effect",UPN2_069,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),44072,1214,45507,"0,0266772145",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"31,72","31,07"
"many samples, low freq, neutral effect",UPN2_070,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),27530,835,28507,"0,0292910513",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"31,8","31,25"
"many samples, low freq, neutral effect",UPN2_071,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),22266,690,23094,"0,0298778904",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"31,61","31,32"
"many samples, low freq, neutral effect",UPN2_072,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),26298,848,27235,"0,0311364054",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"31,72","31,23"
"many samples, low freq, neutral effect",UPN2_073,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),29386,826,30330,"0,027233762",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"31,67","31,22"
"many samples, low freq, neutral effect",UPN2_074,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),22226,807,23144,"0,0348686485",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"31,61","31,17"
"many samples, low freq, neutral effect",UPN2_075,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),40508,1219,41937,"0,0290674106",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"31,63","31,27"
"many samples, low freq, neutral effect",UPN2_076,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),33540,1076,34747,"0,0309667022",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"31,81","31,1"
"many samples, low freq, neutral effect",UPN2_077,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),40776,1300,42250,"0,0307692308",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"31,74","31,04"
"many samples, low freq, neutral effect",UPN2_078,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),35689,1081,36951,"0,0292549593",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"31,79","31,26"
"many samples, low freq, neutral effect",UPN2_079,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),22804,705,23621,"0,0298463232",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"31,7","31,16"
"many samples, low freq, neutral effect",UPN2_080,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),38196,1231,39583,"0,0310992093",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"31,73","31,19"
"many samples, low freq, neutral effect",UPN2_081,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),41105,1124,42401,"0,0265088088",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"31,68","31,23"
"many samples, low freq, neutral effect",UPN2_082,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),39067,1273,40528,"0,0314103829",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"31,65","31,21"
"many samples, low freq, neutral effect",UPN2_083,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),43067,1399,44678,"0,0313129504",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"31,83","31,29"
"many samples, low freq, neutral effect",UPN2_084,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),36787,1115,38137,"0,0292366993",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"31,81","31,11"
"many samples, low freq, neutral effect",UPN2_085,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),29463,1024,30635,"0,0334258201",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"31,76","31,21"
"many samples, low freq, neutral effect",UPN2_086,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),20533,754,21376,"0,0352732036",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"31,79","31,36"
"many samples, low freq, neutral effect",UPN2_087,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),46012,1436,47662,"0,0301288238",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"31,72","31,16"
"many samples, low freq, neutral effect",UPN2_088,20,31023637,C,G,missense_variant(MODERATE|MISSENSE|gCc/gGc|p.Ala1041Gly/c.3122C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),34293,1134,35588,"0,0318646735",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,57",Neutral,"0,064",Tolerated,"31,63","31,09"
"low freq, many artifacts",UPN2_044,20,31023673,T,C,missense_variant(MODERATE|MISSENSE|gTt/gCt|p.Val1053Ala/c.3158T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6636,97,6770,"0,0143279173",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,98",Neutral,"0,026",Damaging,"34,1","34,74"
"low freq, many artifacts",UPN2_044,20,31023706,G,GC,frameshift_variant(HIGH||tgg/Ctgg|p.Trp1065fs/c.3192dupC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GC|INFO_REALIGN_3_PRIME),6440,68,6455,"0,0105344694",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,89",NA
"low freq, many artifacts",UPN2_044,20,31023710,G,T,missense_variant(MODERATE|MISSENSE|tgG/tgT|p.Trp1065Cys/c.3195G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),6352,91,6460,"0,0140866873",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,63",Deleterious,"0,002",Damaging,"34,44","33,23"
"low bq, many samples",UPN2_001,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),18016,1758,19918,"0,0882618737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,74,Tolerated,"28,61","17,81"
"low bq, many samples",UPN2_014,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),30352,4812,35411,"0,1358899777",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,74,Tolerated,"29,69","17,59"
"low bq, many samples, low freq, neutral effect",UPN2_015,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),37362,6666,44386,"0,15018249",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,49","18,01"
"low bq, many samples, low freq, neutral effect",UPN2_016,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),19103,2948,22185,"0,1328825783",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,69","17,65"
"low bq, many samples",UPN2_017,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),13580,2286,15979,"0,1430627699",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,74,Tolerated,"29,64","17,89"
"low bq, many samples, low freq, neutral effect",UPN2_018,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),19949,3227,23330,"0,13831976",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,61","17,74"
"low bq, many samples, low freq, neutral effect",UPN2_019,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),22654,3801,26632,"0,14272304",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,63","17,86"
"low bq, many samples, low freq, neutral effect",UPN2_020,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),20350,3271,23806,"0,1374023355",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,71","17,7"
"low bq, many samples, low freq, neutral effect",UPN2_021,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),21700,3651,25530,"0,1430082256",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,61","17,82"
"low bq, many samples, low freq, neutral effect",UPN2_002,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),23671,2722,26578,"0,1024155316",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"28,42","17,42"
"low bq, many samples, low freq, neutral effect",UPN2_003,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),4509,518,5056,"0,1024525316",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"28,4","17,96"
"low bq, many samples, low freq, neutral effect",UPN2_022,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),29639,4851,34731,"0,1396734905",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,56","17,84"
"low bq, many samples, low freq, neutral effect",UPN2_023,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),32993,5500,38766,"0,1418769024",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,65","17,67"
"low bq, many samples, low freq, neutral effect",UPN2_041,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),61972,4734,67275,"0,070367893",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,04","17,07"
"low bq, many samples, low freq, neutral effect",UPN2_024,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),14890,2467,17486,"0,141084296",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,41","17,89"
"low bq, many samples, low freq, neutral effect",UPN2_025,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),34474,5615,40303,"0,1393196536",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,54","17,54"
"low bq, many samples, low freq, neutral effect",UPN2_026,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),35433,6099,41846,"0,1457486976",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,7",18
"low bq, many samples",UPN2_004,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3776,322,4130,"0,0779661017",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,74,Tolerated,"29,59","17,66"
"low bq, many samples, low freq, neutral effect",UPN2_027,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),38580,6608,45464,"0,1453457681",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,49","17,76"
"low bq, many samples, low freq, neutral effect",UPN2_089,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),24286,3556,27996,"0,1270181454",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,68","18,84"
"low bq, many samples, low freq, neutral effect",UPN2_042,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),52835,4524,57888,"0,0781509121",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"28,45","16,86"
"low bq, many samples, low freq, neutral effect",UPN2_028,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),27627,4798,32651,"0,1469480261",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,6","18,02"
"low bq, many samples, low freq, neutral effect",UPN2_043,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),34761,3103,38200,"0,0812303665",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"28,36","17,1"
"low bq, many samples, low freq, neutral effect",UPN2_044,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9716,999,10794,"0,0925514175",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"27,86","16,82"
"low bq, many samples, low freq, neutral effect",UPN2_029,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),34558,5549,40402,"0,1373446859",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,76","17,78"
"low bq, many samples, low freq, neutral effect",UPN2_030,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),31125,5379,36762,"0,1463195691",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,46","17,82"
"low bq, many samples, low freq, neutral effect",UPN2_031,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),20516,3408,24072,"0,1415752742",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,45","17,74"
"low bq, many samples",UPN2_005,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),7827,872,8737,"0,0998054252",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,74,Tolerated,"28,41","17,55"
"low bq, many samples, low freq, neutral effect",UPN2_045,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),48272,4378,53154,"0,0823644505",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"28,38","17,34"
"low bq, many samples, low freq, neutral effect",UPN2_032,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),11729,1913,13738,"0,139248799",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,4","17,6"
"low bq, many samples, low freq, neutral effect",UPN2_046,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),43821,4213,48465,"0,0869287114",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"28,26","17,15"
"low bq, many samples, low freq, neutral effect",UPN2_033,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),24407,3907,28498,"0,1370973402",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,55","17,49"
"low bq, many samples",UPN2_034,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9613,1745,11436,"0,1525883176",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,74,Tolerated,"29,62","17,67"
"low bq, many samples, low freq, neutral effect",UPN2_047,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),63624,5611,69813,"0,0803718505",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"28,44","17,04"
"low bq, many samples, low freq, neutral effect",UPN2_048,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),58919,5095,64503,"0,0789885742",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"28,54","17,16"
"low bq, many samples, low freq, neutral effect",UPN2_035,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),27558,4479,32231,"0,1389655921",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,52","17,9"
"low bq, many samples, low freq, neutral effect",UPN2_036,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),27133,4510,31830,"0,1416902293",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,53","17,62"
"low bq, many samples",UPN2_006,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),12218,1386,13734,"0,1009174312",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,74,Tolerated,"28,26","17,56"
"low bq, many samples, low freq, neutral effect",UPN2_049,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),30818,2642,33768,"0,0782397536",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"28,18","16,95"
"low bq, many samples, low freq, neutral effect",UPN2_050,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),44286,3976,48725,"0,0816008209",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"28,04","16,86"
"low bq, many samples, low freq, neutral effect",UPN2_037,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),51151,8979,60570,"0,1482417038",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,46","18,16"
"low bq, many samples, low freq, neutral effect",UPN2_051,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),34040,3147,37510,"0,0838976273",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"28,17","16,89"
"low bq, many samples, low freq, neutral effect",UPN2_052,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),40213,3792,44427,"0,0853535012",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,28,"17,3"
"low bq, many samples, low freq, neutral effect",UPN2_038,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),55387,9190,65033,"0,1413128719",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,45","17,79"
"low bq, many samples, low freq, neutral effect",UPN2_039,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),24382,4296,28882,"0,1487431618",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,58","18,11"
"low bq, many samples, low freq, neutral effect",UPN2_053,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),47525,4283,52245,"0,0819791368",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"28,08","17,14"
"low bq, many samples, low freq, neutral effect",UPN2_054,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),31013,2897,34282,"0,084504988",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"28,24","16,91"
"low bq, many samples, low freq, neutral effect",UPN2_007,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),52542,5289,58201,"0,0908747272",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"28,67","17,59"
"low bq, many samples, low freq, neutral effect",UPN2_008,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),74051,8324,82850,"0,1004707302",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"28,68","17,7"
"low bq, many samples, low freq, neutral effect",UPN2_009,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),57613,6240,64288,"0,0970632155",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"28,63","17,77"
"low bq, many samples, low freq, neutral effect",UPN2_010,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),40900,4656,45823,"0,1016083626",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"28,49","17,77"
"low bq, many samples, low freq, neutral effect",UPN2_011,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),49758,5448,55562,"0,0980526259",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"28,64","17,55"
"low bq, many samples, low freq, neutral effect",UPN2_055,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),51317,4555,56386,"0,0807824637",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"28,23","16,95"
"low bq, many samples, low freq, neutral effect",UPN2_056,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),10536,996,11616,"0,0857438017",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"28,36",17
"low bq, many samples, low freq, neutral effect",UPN2_090,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),21736,3284,25197,"0,1303329761",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,48","18,71"
"low bq, many samples, low freq, neutral effect",UPN2_057,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),43364,3869,47723,"0,0810720198",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"28,33","16,92"
"low bq, many samples, low freq, neutral effect",UPN2_058,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),42735,3987,47183,"0,0845007736",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"28,1","16,91"
"low bq, many samples, low freq, neutral effect",UPN2_059,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),37645,12094,50024,"0,2417639533",1,1,0,0,1,1,0,0,4,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"30,53","23,26"
"low bq, many samples, low freq, neutral effect",UPN2_012,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),26152,2812,29136,"0,096512905",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"28,48","17,55"
"low bq, many samples, low freq, neutral effect",UPN2_060,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),28230,7025,35405,"0,1984183025",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"30,98","23,01"
"low bq, many samples, low freq, neutral effect",UPN2_040,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),19965,3272,23415,"0,1397394832",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,62","17,78"
"low bq, many samples",UPN2_013,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),15087,1555,16758,"0,0927915026",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,74,Tolerated,"28,42","17,28"
"low bq, many samples",UPN2_091,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),15721,2177,17977,"0,1210991823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,74,Tolerated,"29,5","18,53"
"low bq, many samples, low freq, neutral effect",UPN2_092,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),12522,1766,14352,"0,1230490524",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,74","18,49"
"low bq, many samples, low freq, neutral effect",UPN2_093,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),14227,1994,16290,"0,1224063843",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,62","18,63"
"low bq, many samples, low freq, neutral effect",UPN2_061,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),27468,7075,34755,"0,203567832",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"30,93","23,51"
"low bq, many samples, low freq, neutral effect",UPN2_062,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),24513,6650,31353,"0,2121009154",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"30,91","23,74"
"low bq, many samples, low freq, neutral effect",UPN2_063,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),27588,7318,35130,"0,2083119841",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"30,98","23,61"
"low bq, many samples, low freq, neutral effect",UPN2_064,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),28630,8251,37070,"0,2225789048",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"30,78","23,5"
"low bq, many samples, low freq, neutral effect",UPN2_065,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),30428,9118,39805,"0,2290667002",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"30,5","23,45"
"low bq, many samples, low freq, neutral effect",UPN2_066,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),34340,10719,45336,"0,2364346215",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"30,31","23,15"
"low bq, many samples, low freq, neutral effect",UPN2_067,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),30337,9202,39851,"0,2309101403",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"30,4","23,18"
"low bq, many samples, low freq, neutral effect",UPN2_068,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),27467,7984,35696,"0,2236665173",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"30,62","23,75"
"low bq, many samples, low freq, neutral effect",UPN2_069,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),34738,9022,44045,"0,2048359632",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"30,84","23,59"
"low bq, many samples, low freq, neutral effect",UPN2_070,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),22229,5933,28368,"0,209144106",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"30,62","23,88"
"low bq, many samples, low freq, neutral effect",UPN2_071,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),17584,4288,21973,"0,1951485915",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"30,78","23,64"
"low bq, many samples, low freq, neutral effect",UPN2_072,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),20824,5400,26393,"0,2045997045",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"30,87","23,47"
"low bq, many samples, low freq, neutral effect",UPN2_073,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),23256,5870,29323,"0,2001841558",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"30,84","23,59"
"low bq, many samples, low freq, neutral effect",UPN2_074,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),19217,5410,24746,"0,2186211913",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"30,58","23,14"
"low bq, many samples, low freq, neutral effect",UPN2_075,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),32198,7836,40323,"0,194330779",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"30,85","23,06"
"low bq, many samples, low freq, neutral effect",UPN2_076,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),26722,6992,33940,"0,206010607",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"30,8","23,92"
"low bq, many samples, low freq, neutral effect",UPN2_077,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),33524,8865,42665,"0,207781554",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"30,66","23,6"
"low bq, many samples, low freq, neutral effect",UPN2_078,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),27956,7087,35250,"0,2010496454",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"30,7","23,81"
"low bq, many samples, low freq, neutral effect",UPN2_079,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),17864,4431,22452,"0,197354356",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"30,94","23,45"
"low bq, many samples, low freq, neutral effect",UPN2_080,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),29959,7475,37640,"0,1985919235",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"30,81","23,4"
"low bq, many samples, low freq, neutral effect",UPN2_081,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),32993,8463,41695,"0,2029739777",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"30,92","23,45"
"low bq, many samples, low freq, neutral effect",UPN2_082,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),35517,10680,46535,"0,2295046739",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"30,48","23,37"
"low bq, many samples, low freq, neutral effect",UPN2_083,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),33751,8744,42714,"0,2047103994",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"31,03","23,78"
"low bq, many samples, low freq, neutral effect",UPN2_084,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),29834,8322,38405,"0,2166905351",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"30,82","23,45"
"low bq, many samples, low freq, neutral effect",UPN2_085,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),26721,8073,34997,"0,2306769152",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"30,47","23,4"
"low bq, many samples, low freq, neutral effect",UPN2_086,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),18604,6171,24939,"0,2474437628",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"30,57","23,7"
"low bq, many samples, low freq, neutral effect",UPN2_087,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),38539,10615,49474,"0,2145571411",0,1,0,0,1,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"30,76","23,58"
"low bq, many samples, low freq, neutral effect",UPN2_088,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),28903,7711,36857,"0,2092139892",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"30,75","23,14"
"low bq, many samples, low freq, neutral effect",UPN2_094,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),26692,3925,30787,"0,1274888752",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,62","18,41"
"low bq, many samples, low freq, neutral effect",UPN2_095,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),22790,3453,26391,"0,1308400591",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,62","18,57"
"low bq, many samples, low freq, neutral effect",UPN2_096,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),24221,3477,27834,"0,1249191636",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,81","18,49"
"low bq, many samples, low freq, neutral effect",UPN2_097,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),26982,3897,31055,"0,1254870391",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,65","18,63"
"low bq, many samples, low freq, neutral effect",UPN2_098,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),20983,2814,23904,"0,1177208835",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,66","18,25"
"low bq, many samples",UPN2_099,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),13171,1802,15059,"0,1196626602",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,74,Tolerated,"29,64","18,46"
"low bq, many samples, low freq, neutral effect",UPN2_100,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),21370,2945,24424,"0,1205781199",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,61","18,5"
"low bq, many samples, low freq, neutral effect",UPN2_101,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),21607,3265,25014,"0,1305269049",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,43","18,78"
"low bq, many samples, low freq, neutral effect",UPN2_102,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),23380,3444,26992,"0,127593361",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,59","18,6"
"low bq, many samples",UPN2_103,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),20330,3076,23549,"0,1306212578",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,74,Tolerated,"29,54","18,94"
"low bq, many samples, low freq, neutral effect",UPN2_104,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),26535,3668,30380,"0,1207373272",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,54","18,63"
low bq,UPN2_105,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),23965,3496,27601,"0,1266620775",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,74,Tolerated,"29,58","18,54"
"low bq, many samples, low freq, neutral effect",UPN2_106,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),29767,4051,34013,"0,11910152",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,95","18,7"
"low bq, many samples, low freq, neutral effect",UPN2_107,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),36896,5182,42271,"0,1225899553",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,64","18,34"
"low bq, many samples, low freq, neutral effect",UPN2_108,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),33701,4921,38836,"0,1267123288",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,63","18,53"
"low bq, many samples, low freq, neutral effect",UPN2_109,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),30676,4637,35515,"0,1305645502",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,59","18,8"
"low bq, many samples, low freq, neutral effect",UPN2_110,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),33572,4797,38603,"0,1242649535",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,65","18,53"
"low bq, many samples, low freq, neutral effect",UPN2_111,20,31023712,T,G,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val1066Gly/c.3197T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),27386,4024,31580,"0,1274224193",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,074",Tolerated,"29,65","18,73"
"low freq, many artifacts",UPN2_006,20,31023718,G,A,missense_variant(MODERATE|MISSENSE|cGa/cAa|p.Arg1068Gln/c.3203G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),13650,144,13808,"0,010428737",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"2,47E-005",NO,NO,"-0,33",Neutral,"0,003",Damaging,"34,04","33,18"
"many samples, low freq, no database",UPN2_001,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),18921,1029,20043,"0,0513396198",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,72","31,61"
"many samples, low freq, no database",UPN2_014,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),33861,1489,35490,"0,0419554804",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,37","31,73"
"many samples, low freq, no database",UPN2_015,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),43038,1435,44639,"0,0321467775",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,15","31,73"
"many samples, low freq, no database",UPN2_016,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),21314,901,22281,"0,0404380414",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,43","31,82"
"many samples, low freq, no database",UPN2_017,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),15343,644,16050,"0,0401246106",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,13","31,66"
"many samples, low freq, no database",UPN2_018,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),22449,899,23439,"0,0383548786",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,3","31,63"
"many samples, low freq, no database",UPN2_019,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),25550,1131,26760,"0,042264574",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,25","31,68"
"many samples, low freq, no database",UPN2_020,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),22831,1065,23964,"0,0444416625",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,23","31,63"
"many samples, low freq, no database",UPN2_021,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),24480,1114,25692,"0,0433598007",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,29","31,57"
"many samples, low freq, no database",UPN2_002,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),25439,1232,26756,"0,0460457467",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,44","31,53"
"many samples, low freq, no database",UPN2_003,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4858,218,5089,"0,0428374926",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,47","31,73"
"many samples, low freq, no database",UPN2_022,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),33357,1378,34863,"0,0395261452",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,33","31,68"
"many samples, low freq, no database",UPN2_023,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),37220,1589,38962,"0,0407833273",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,36","31,57"
"many samples, low freq, no database",UPN2_041,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),65139,1740,67289,"0,0258586099",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,31","31,77"
"many samples, low freq, no database",UPN2_024,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16940,595,17605,"0,0337972167",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,28","31,75"
"many samples, low freq, no database",UPN2_025,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),38729,1577,40466,"0,038970988",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,43","31,7"
"many samples, low freq, no database",UPN2_026,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),40214,1765,42166,"0,0418583693",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,23","31,71"
"many samples, low freq, no database",UPN2_004,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3784,330,4130,"0,0799031477",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,3","31,32"
"many samples, low freq, no database",UPN2_027,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),43667,1821,45675,"0,0398686371",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,26","31,75"
"many samples, low freq, no database",UPN2_089,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),27790,453,28307,"0,0160031088",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,93","31,85"
"many samples, low freq, no database",UPN2_042,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),56457,1357,58173,"0,023326973",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,53","31,66"
"many samples, low freq, no database",UPN2_028,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),31441,1280,32852,"0,0389626202",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,24","31,78"
"many samples, low freq, no database",UPN2_043,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),37344,794,38390,"0,0206824694",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,5","31,67"
"many samples, low freq, no database",UPN2_044,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),10586,217,10841,"0,0200166036",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,58","31,63"
"many samples, low freq, no database",UPN2_029,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),38764,1663,40614,"0,0409464717",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,26","31,6"
"many samples, low freq, no database",UPN2_030,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),35410,1384,36929,"0,0374773213",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,34","31,73"
"many samples, low freq, no database",UPN2_031,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),23177,914,24198,"0,0377717167",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,32","31,81"
"many samples, low freq, no database",UPN2_005,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),8313,456,8796,"0,0518417462",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,58","31,83"
"many samples, low freq, no database",UPN2_045,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),52170,1004,53429,"0,0187912931",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,39","31,84"
"many samples, low freq, no database",UPN2_032,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),13312,462,13817,"0,0334370703",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,38","31,58"
"many samples, low freq, no database",UPN2_046,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),47270,1288,48817,"0,0263842514",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,44","31,64"
"many samples, low freq, no database",UPN2_033,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),27398,1134,28631,"0,0396074185",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,39","31,71"
"many samples, low freq, no database",UPN2_034,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),11100,377,11520,"0,0327256944",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,33","31,73"
"many samples, low freq, no database",UPN2_047,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),68109,1713,70190,"0,0244051859",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,42","31,65"
"many samples, low freq, no database",UPN2_048,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),62709,1784,64873,"0,0274998844",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,39","31,49"
"many samples, low freq, no database",UPN2_035,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),30874,1390,32397,"0,0429052073",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,28","31,61"
"many samples, low freq, no database",UPN2_036,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),30546,1297,31965,"0,0405756296",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,34","31,7"
"many samples, low freq, no database",UPN2_006,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),13166,522,13751,"0,0379608756",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,57","31,63"
"many samples, low freq, no database",UPN2_049,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),33015,735,33928,"0,0216635228",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,49","31,9"
"many samples, low freq, no database",UPN2_050,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),48173,712,49146,"0,0144874456",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,54","31,58"
"many samples, low freq, no database",UPN2_037,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),58472,2276,60952,"0,0373408584",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,24","31,69"
"many samples, low freq, no database",UPN2_051,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),36921,660,37779,"0,017470023",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,56","31,7"
"many samples, low freq, no database",UPN2_052,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),43703,763,44768,"0,0170434239",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,48","31,88"
"many samples, low freq, no database",UPN2_038,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),62571,2638,65444,"0,040309272",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,27","31,67"
"many samples, low freq, no database",UPN2_039,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),27684,1253,29034,"0,0431562995",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,2","31,68"
"many samples, low freq, no database",UPN2_053,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),51006,1323,52597,"0,0251535259",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,48","31,74"
"many samples, low freq, no database",UPN2_054,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),33554,754,34472,"0,0218728243",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,38","31,93"
"many samples, low freq, no database",UPN2_007,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),55614,2780,58587,"0,0474507997",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,58","31,7"
"many samples, low freq, no database",UPN2_008,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),79307,3857,83483,"0,046201023",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,34","31,67"
"many samples, low freq, no database",UPN2_009,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),61672,2856,64779,"0,044088362",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,36","31,6"
"many samples, low freq, no database",UPN2_010,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),44038,1920,46113,"0,0416368486",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,38","31,55"
"many samples, low freq, no database",UPN2_011,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),53034,2567,55793,"0,046009356",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,4","31,61"
"many samples, low freq, no database",UPN2_055,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),55172,1320,56764,"0,0232541752",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,49","31,61"
"many samples, low freq, no database",UPN2_056,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),11390,258,11727,"0,0220005116",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,48","31,65"
"many samples, low freq, no database",UPN2_090,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),25056,323,25469,"0,0126820841",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"33,01","32,26"
"many samples, low freq, no database",UPN2_057,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),46550,1256,48026,"0,0261525007",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,46","31,85"
"many samples, low freq, no database",UPN2_058,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),45917,1232,47422,"0,0259795032",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,57","31,58"
"many samples, low freq, no database",UPN2_059,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),49488,1699,51728,"0,0328448809",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"31,29","31,54"
"many samples, low freq, no database",UPN2_012,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),27910,1282,29310,"0,0437393381",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,45","31,6"
"many samples, low freq, no database",UPN2_060,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),34052,2007,36420,"0,055107084",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"31,4","31,59"
"many samples, low freq, no database",UPN2_040,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),22459,1006,23587,"0,0426506126",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,25","31,77"
"many samples, low freq, no database",UPN2_013,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16170,634,16859,"0,0376060265",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,47","31,5"
"many samples, low freq, no database",UPN2_091,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),17759,323,18138,"0,0178079171",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"33,01","31,84"
"many samples, low freq, no database",UPN2_092,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),14148,249,14442,"0,0172413793",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,99","32,07"
"many samples, low freq, no database",UPN2_093,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16145,222,16403,"0,0135341096",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"33,05","32,14"
"many samples, low freq, no database",UPN2_061,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),33522,1955,35850,"0,0545327755",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"31,21","31,62"
"many samples, low freq, no database",UPN2_062,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),30250,1790,32351,"0,0553305926",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"31,11","31,61"
"many samples, low freq, no database",UPN2_063,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),33717,2090,36151,"0,0578130619",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"31,21","31,58"
"many samples, low freq, no database",UPN2_064,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),36057,1953,38398,"0,0508620241",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"31,28","31,62"
"many samples, low freq, no database",UPN2_065,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),39305,1579,41338,"0,0381973003",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"31,25","31,55"
"many samples, low freq, no database",UPN2_066,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),44955,1558,47003,"0,0331468204",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"31,27","31,55"
"many samples, low freq, no database",UPN2_067,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),39240,1548,41196,"0,0375764637",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"31,42","31,45"
"many samples, low freq, no database",UPN2_068,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),34899,1615,36975,"0,0436781609",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"31,08","31,64"
"many samples, low freq, no database",UPN2_069,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),42691,2338,45484,"0,0514026911",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"31,13","31,57"
"many samples, low freq, no database",UPN2_070,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),27489,1476,29286,"0,0503995083",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"31,15","31,57"
"many samples, low freq, no database",UPN2_071,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),21096,1344,22657,"0,0593194156",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"31,18","31,56"
"many samples, low freq, no database",UPN2_072,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),25526,1485,27242,"0,0545114162",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"31,2","31,45"
"many samples, low freq, no database",UPN2_073,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),28186,1698,30169,"0,0562829394",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"31,33","31,41"
"many samples, low freq, no database",UPN2_074,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),24110,1188,25538,"0,046518913",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"31,33","31,43"
"many samples, low freq, no database",UPN2_075,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),38796,2338,41434,"0,0564270889",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"31,43","31,54"
"many samples, low freq, no database",UPN2_076,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),32556,2023,34966,"0,0578562032",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"31,2","31,45"
"many samples, low freq, no database",UPN2_077,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),41492,2128,44091,"0,048263818",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"31,19","31,61"
"many samples, low freq, no database",UPN2_078,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),33977,2053,36354,"0,0564724652",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"31,16","31,56"
"many samples, low freq, no database",UPN2_079,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),21591,1347,23164,"0,0581505785",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"31,32","31,35"
"many samples, low freq, no database",UPN2_080,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),36060,2357,38787,"0,060767783",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"31,3","31,64"
"many samples, low freq, no database",UPN2_081,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),40380,2045,42840,"0,047735761",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"31,35","31,46"
"many samples, low freq, no database",UPN2_082,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),45984,1684,48151,"0,0349733131",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"31,38","31,75"
"many samples, low freq, no database",UPN2_083,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),40967,2666,44082,"0,0604781997",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"31,18","31,57"
"many samples, low freq, no database",UPN2_084,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),37335,1973,39725,"0,0496664569",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"31,12","31,59"
"many samples, low freq, no database",UPN2_085,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),34682,1305,36378,"0,03587333",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"31,24","31,57"
"many samples, low freq, no database",UPN2_086,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),24697,874,25873,"0,0337803888",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"31,12","31,55"
"many samples, low freq, no database",UPN2_087,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),48123,2489,51126,"0,0486836443",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"31,24","31,57"
"many samples, low freq, no database",UPN2_088,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),35629,1927,37896,"0,0508496939",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"31,45","31,53"
"many samples, low freq, no database",UPN2_094,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),30474,475,31056,"0,0152949511",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"33,01","31,65"
"many samples, low freq, no database",UPN2_095,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),26213,387,26663,"0,0145144957",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,9","31,77"
"many samples, low freq, no database",UPN2_096,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),27633,423,28122,"0,0150416044",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,94","31,98"
"many samples, low freq, no database",UPN2_097,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),30681,542,31318,"0,0173063414",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,92","32,09"
"many samples, low freq, no database",UPN2_098,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),23556,439,24077,"0,0182331686",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,91","32,12"
"many samples, low freq, no database",UPN2_099,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),14930,254,15223,"0,0166852789",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"33,02","32,16"
"many samples, low freq, no database",UPN2_100,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),24250,325,24648,"0,013185654",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"33,14","31,5"
"many samples, low freq, no database",UPN2_101,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),24813,334,25223,"0,0132418824",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,96","32,04"
"many samples, low freq, no database",UPN2_102,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),26728,410,27239,"0,0150519476",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"33,04","31,89"
"many samples, low freq, no database",UPN2_103,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),23327,378,23787,"0,0158910329",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,97","31,75"
"many samples, low freq, no database",UPN2_104,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),30076,513,30671,"0,0167258974",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"33,02","31,86"
"many samples, low freq, no database",UPN2_105,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),27397,383,27853,"0,0137507629",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"33,02","31,73"
"many samples, low freq, no database",UPN2_106,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),33701,521,34300,"0,0151895044",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,93","31,78"
"many samples, low freq, no database",UPN2_107,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),41876,625,42615,"0,0146661973",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"33,05","32,05"
"many samples, low freq, no database",UPN2_108,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),38533,472,39130,"0,0120623562",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"33,07","32,03"
"many samples, low freq, no database",UPN2_109,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),35297,440,35844,"0,0122754157",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,85","31,97"
"many samples, low freq, no database",UPN2_110,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),38393,406,38912,"0,0104337993",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,93","32,16"
"many samples, low freq, no database",UPN2_111,20,31023723,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys1070Arg/c.3208T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),31363,458,31904,"0,0143555667",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,86",Neutral,0,Damaging,"32,88","32,11"
"low bq, low freq, many artifacts, many samples",UPN2_059,20,31023725,T,G,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys1070Trp/c.3210T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),39753,468,40528,"0,011547572",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,76",Deleterious,0,Damaging,"28,89","15,37"
"low bq, low freq, many artifacts, many samples",UPN2_060,20,31023725,T,G,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys1070Trp/c.3210T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),23644,268,24094,"0,0111231012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,76",Deleterious,0,Damaging,"28,93","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_061,20,31023725,T,G,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys1070Trp/c.3210T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),23493,268,23959,"0,0111857757",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,76",Deleterious,0,Damaging,"28,83","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_062,20,31023725,T,G,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys1070Trp/c.3210T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),21622,306,22101,"0,0138455274",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,76",Deleterious,0,Damaging,"28,66","15,49"
"low bq, low freq, many artifacts, many samples",UPN2_063,20,31023725,T,G,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys1070Trp/c.3210T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),24039,326,24569,"0,0132687533",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,76",Deleterious,0,Damaging,"28,88","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_064,20,31023725,T,G,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys1070Trp/c.3210T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),27295,369,27862,"0,0132438447",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,76",Deleterious,0,Damaging,"28,83","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_065,20,31023725,T,G,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys1070Trp/c.3210T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),30587,407,31276,"0,013013173",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,76",Deleterious,0,Damaging,"28,79","15,37"
"low bq, low freq, many artifacts, many samples",UPN2_066,20,31023725,T,G,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys1070Trp/c.3210T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),36735,423,37454,"0,0112938538",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,76",Deleterious,0,Damaging,"28,91","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_067,20,31023725,T,G,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys1070Trp/c.3210T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),31282,353,31856,"0,011081115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,76",Deleterious,0,Damaging,"29,09","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_068,20,31023725,T,G,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys1070Trp/c.3210T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),26057,405,26674,"0,0151833246",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,76",Deleterious,0,Damaging,"28,6","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_069,20,31023725,T,G,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys1070Trp/c.3210T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),29767,394,30408,"0,0129571165",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,76",Deleterious,0,Damaging,"28,75","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_070,20,31023725,T,G,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys1070Trp/c.3210T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),19611,290,20040,"0,0144710579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,76",Deleterious,0,Damaging,"28,65","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_071,20,31023725,T,G,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys1070Trp/c.3210T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),14522,206,14842,"0,0138795311",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,76",Deleterious,0,Damaging,"28,79","15,39"
"low bq, low freq, many artifacts, many samples",UPN2_072,20,31023725,T,G,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys1070Trp/c.3210T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),17761,231,18137,"0,0127363952",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,76",Deleterious,0,Damaging,"28,82","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_073,20,31023725,T,G,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys1070Trp/c.3210T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),19686,203,20037,"0,0101312572",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,76",Deleterious,0,Damaging,"28,87","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_074,20,31023725,T,G,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys1070Trp/c.3210T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),18242,211,18586,"0,011352631",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,76",Deleterious,0,Damaging,"28,85","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_075,20,31023725,T,G,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys1070Trp/c.3210T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),26797,317,27297,"0,0116129978",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,76",Deleterious,0,Damaging,"29,06","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_076,20,31023725,T,G,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys1070Trp/c.3210T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),23007,313,23523,"0,0133061259",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,76",Deleterious,0,Damaging,"28,75","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_077,20,31023725,T,G,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys1070Trp/c.3210T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),29874,440,30575,"0,0143908422",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,76",Deleterious,0,Damaging,"28,81","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_078,20,31023725,T,G,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys1070Trp/c.3210T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),23398,286,23850,"0,0119916143",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,76",Deleterious,0,Damaging,"28,65","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_079,20,31023725,T,G,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys1070Trp/c.3210T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),14815,192,15122,"0,0126967332",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,76",Deleterious,0,Damaging,"28,83","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_080,20,31023725,T,G,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys1070Trp/c.3210T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),24841,313,25373,"0,0123359477",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,76",Deleterious,0,Damaging,"28,79","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_081,20,31023725,T,G,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys1070Trp/c.3210T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),28289,387,28889,"0,0133961023",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,76",Deleterious,0,Damaging,"28,88","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_082,20,31023725,T,G,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys1070Trp/c.3210T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),36290,441,37019,"0,0119128015",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,76",Deleterious,0,Damaging,"28,94","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_083,20,31023725,T,G,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys1070Trp/c.3210T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),28401,407,29036,"0,0140170822",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,76",Deleterious,0,Damaging,"28,63","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_084,20,31023725,T,G,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys1070Trp/c.3210T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),26861,357,27461,"0,0130002549",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,76",Deleterious,0,Damaging,"28,63","15,45"
"low bq, low freq, many artifacts, many samples",UPN2_085,20,31023725,T,G,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys1070Trp/c.3210T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),27334,364,27922,"0,0130363155",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,76",Deleterious,0,Damaging,"28,69","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_086,20,31023725,T,G,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys1070Trp/c.3210T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),19781,270,20213,"0,0133577401",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,76",Deleterious,0,Damaging,"28,69","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_087,20,31023725,T,G,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys1070Trp/c.3210T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),35545,476,36306,"0,0131107806",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,76",Deleterious,0,Damaging,"28,88","14,88"
"low bq, low freq, many artifacts",UPN2_088,20,31023725,T,G,missense_variant(MODERATE|MISSENSE|tgT/tgG|p.Cys1070Trp/c.3210T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),26294,285,26820,"0,0106263982",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,76",Deleterious,0,Damaging,"29,13","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_089,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),20810,239,21124,"0,011314145",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"29,17","14,67"
"low bq, many samples",UPN2_059,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),38653,1751,40555,"0,0431759339",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"27,28","15,28"
"low bq, many samples",UPN2_060,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),23041,957,24103,"0,0397046011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"27,35","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_091,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),13408,150,13606,"0,011024548",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"29,37","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_093,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),12102,123,12257,"0,010035082",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"29,44","14,32"
"low bq, many samples",UPN2_061,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),22829,1038,23969,"0,0433059368",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"27,12","15,03"
"low bq, many samples",UPN2_062,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),21022,993,22104,"0,0449239957",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"27,08","14,96"
"low bq, many samples",UPN2_063,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),23401,1061,24578,"0,0431686874",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"27,28","15,02"
"low bq, many samples",UPN2_064,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),26531,1226,27886,"0,0439647135",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"27,31","15,1"
"low bq, many samples",UPN2_065,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),29805,1341,31292,"0,0428544037",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"27,3","15,11"
"low bq, many samples",UPN2_066,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),35722,1571,37473,"0,0419235183",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"27,38","14,98"
"low bq, many samples",UPN2_067,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),30448,1285,31867,"0,040323846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"27,5","15,03"
"low bq, many samples",UPN2_068,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),25314,1210,26685,"0,0453438261",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"27,06","15,13"
"low bq, many samples",UPN2_069,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),28905,1375,30429,"0,045187157",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"27,15","14,84"
"low bq, many samples",UPN2_070,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),18983,998,20052,"0,0497705964",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"27,18","14,8"
"low bq, many samples",UPN2_071,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),14150,649,14851,"0,0437007609",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"27,4",15
"low bq, many samples",UPN2_072,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),17305,750,18150,"0,041322314",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"27,23","14,91"
"low bq, many samples",UPN2_073,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),19159,797,20047,"0,0397565721",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"27,34","15,03"
"low bq, many samples",UPN2_074,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),17748,743,18591,"0,0399655747",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"27,41","14,63"
"low bq, many samples",UPN2_075,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),26108,1074,27311,"0,0393248142",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"27,6","15,04"
"low bq, many samples",UPN2_076,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),22333,1094,23530,"0,0464938377",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"27,19","15,04"
"low bq, many samples",UPN2_077,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),29132,1339,30592,"0,043769613",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"27,19","15,22"
"low bq, many samples",UPN2_078,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),22662,1106,23860,"0,0463537301",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"27,07","15,07"
"low bq, many samples",UPN2_079,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),14388,660,15128,"0,0436277102",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"27,31","14,92"
"low bq, many samples",UPN2_080,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),24114,1157,25388,"0,0455727115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"27,36","14,92"
"low bq, many samples",UPN2_081,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),27521,1250,28910,"0,043237634",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"27,4","14,94"
"low bq, many samples",UPN2_082,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),35327,1502,37037,"0,0405540406",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"27,4","15,03"
"low bq, many samples",UPN2_083,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),27594,1334,29048,"0,0459239879",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"27,09","14,98"
"low bq, many samples",UPN2_084,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),26123,1203,27477,"0,0437820723",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"27,07",15
"low bq, many samples",UPN2_085,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),26552,1267,27947,"0,0453358142",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"27,18","15,01"
"low bq, many samples",UPN2_086,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),19151,967,20226,"0,0478097498",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"27,09","14,96"
"low bq, many samples",UPN2_087,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),34604,1553,36320,"0,0427588106",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"27,38","15,12"
"low bq, many samples",UPN2_088,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),25650,1051,26827,"0,0391769486",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"27,52",15
"low bq, low freq, many artifacts, many samples",UPN2_094,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),22864,244,23198,"0,0105181481",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"29,34","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_095,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),19720,214,19996,"0,0107021404",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"29,17","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_096,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),20327,212,20605,"0,0102887649",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"29,32","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_097,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),22793,256,23109,"0,011077935",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"29,26","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_101,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),18762,215,19039,"0,0112926099",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"29,21","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_104,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),22528,235,22818,"0,0102988868",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"29,33","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_106,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),23703,247,24051,"0,0102698432",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"29,3","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_109,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),26398,293,26775,"0,0109430439",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"29,21","14,53"
"low bq, low freq, many artifacts",UPN2_111,20,31023730,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1072Gly/c.3215T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),23292,257,23636,"0,0108732442",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,184,Tolerated,"29,12","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_061,20,31023741,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1076Leu/c.3226A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),23632,249,23975,"0,0103858186",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,11,Damaging,"28,95","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_062,20,31023741,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1076Leu/c.3226A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),21792,223,22120,"0,0100813743",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,11,Damaging,"28,91","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_064,20,31023741,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1076Leu/c.3226A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),27513,300,27910,"0,0107488355",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,11,Damaging,"29,13","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_068,20,31023741,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1076Leu/c.3226A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),26330,281,26703,"0,0105231622",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,11,Damaging,"28,93","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_069,20,31023741,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1076Leu/c.3226A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),30023,338,30450,"0,0111001642",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,11,Damaging,"29,09","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_070,20,31023741,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1076Leu/c.3226A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),19762,232,20056,"0,0115676107",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,11,Damaging,"28,94","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_071,20,31023741,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1076Leu/c.3226A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),14658,150,14858,"0,0100955714",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,11,Damaging,"29,16","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_073,20,31023741,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1076Leu/c.3226A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),19783,217,20067,"0,0108137739",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,11,Damaging,"29,26","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_076,20,31023741,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1076Leu/c.3226A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),23190,258,23541,"0,0109596024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,11,Damaging,"28,95","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_078,20,31023741,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1076Leu/c.3226A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),23529,255,23871,"0,010682418",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,11,Damaging,"28,99","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_080,20,31023741,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1076Leu/c.3226A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),25053,276,25404,"0,0108644308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,11,Damaging,"29,11","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_083,20,31023741,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1076Leu/c.3226A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),28669,301,29070,"0,0103543172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,11,Damaging,"29,02","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_084,20,31023741,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1076Leu/c.3226A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),27084,297,27494,"0,0108023569",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,11,Damaging,"28,92","14,72"
"low bq, low freq, many artifacts",UPN2_085,20,31023741,A,C,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile1076Leu/c.3226A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),27559,281,27959,"0,010050431",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,35",Neutral,11,Damaging,"29,1","14,44"
"low freq, many artifacts",UPN2_006,20,31023776,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr1087*/c.3261C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),11036,133,11230,"0,0118432769",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,74","31,41"
"low bq, low freq, many artifacts, many samples",UPN2_061,20,31023785,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg1090Ser/c.3270A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),23573,248,23916,"0,010369627",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,7,Damaging,"29,43","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_062,20,31023785,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg1090Ser/c.3270A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),21698,245,22040,"0,0111161525",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,7,Damaging,"29,41","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_068,20,31023785,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg1090Ser/c.3270A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),26244,297,26637,"0,0111499043",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,7,Damaging,"29,52","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_069,20,31023785,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg1090Ser/c.3270A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),29924,336,30374,"0,0110620926",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,7,Damaging,"29,52","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_074,20,31023785,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg1090Ser/c.3270A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),18287,206,18571,"0,0110925637",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,7,Damaging,"29,55","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_076,20,31023785,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg1090Ser/c.3270A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),23127,247,23484,"0,0105177994",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,7,Damaging,"29,46","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_078,20,31023785,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg1090Ser/c.3270A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),23471,240,23807,"0,0100810686",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,7,Damaging,"29,44","14,13"
"low bq, low freq, many artifacts, many samples",UPN2_083,20,31023785,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg1090Ser/c.3270A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),28619,291,29002,"0,0100337908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,7,Damaging,"29,53","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_084,20,31023785,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg1090Ser/c.3270A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),27042,307,27440,"0,0111880466",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,7,Damaging,"29,53","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_085,20,31023785,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg1090Ser/c.3270A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),27475,279,27881,"0,0100068147",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,7,Damaging,"29,56","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_086,20,31023785,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg1090Ser/c.3270A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),19920,209,20194,"0,0103496088",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,7,Damaging,"29,52","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_087,20,31023785,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg1090Ser/c.3270A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),35743,367,36266,"0,0101196713",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,7,Damaging,"29,58","14,36"
"low bq, low freq, many artifacts",UPN2_088,20,31023785,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg1090Ser/c.3270A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),26371,280,26761,"0,0104629872",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,62",Neutral,7,Damaging,"29,61","14,44"
"low freq, many artifacts",UPN2_044,20,31023825,A,AC,frameshift_variant(HIGH||act/acCt|p.Asn1105fs/c.3311dupC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AC|INFO_REALIGN_3_PRIME),7011,108,7076,"0,0152628604",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,9",NA
"low freq, many artifacts",UPN2_044,20,31023876,G,A,missense_variant(MODERATE|MISSENSE|Gtt/Att|p.Val1121Ile/c.3361G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),2599,80,2682,"0,0298284862",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,49",Neutral,"0,052",Tolerated,"35,02","35,11"
"low freq, many artifacts",UPN2_044,20,31023888,G,T,missense_variant(MODERATE|MISSENSE|Gcc/Tcc|p.Ala1125Ser/c.3373G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5192,89,5292,"0,0168178382",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,"0,264",Tolerated,"33,31","32,84"
"low freq, many artifacts",UPN2_056,20,31023895,A,T,missense_variant(MODERATE|MISSENSE|gAt/gTt|p.Asp1127Val/c.3380A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),6863,87,6979,"0,0124659693",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,1",Neutral,"0,18",Tolerated,"33,11","31,08"
"low freq, many artifacts",UPN2_044,20,31023925,C,T,missense_variant(MODERATE|MISSENSE|cCa/cTa|p.Pro1137Leu/c.3410C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5168,125,5305,"0,0235626767",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,41",Deleterious,"0,007",Damaging,"33,69","33,37"
"low bq, low freq, many artifacts, many samples",UPN2_059,20,31023937,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1141Ala/c.3422A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),64821,1182,66316,"0,0178237529",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,47",Neutral,12,Damaging,"29,56","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_060,20,31023937,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1141Ala/c.3422A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),39179,693,40086,"0,0172878312",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,47",Neutral,12,Damaging,"29,64","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_061,20,31023937,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1141Ala/c.3422A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),31593,607,32326,"0,0187774547",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,47",Neutral,12,Damaging,"29,42","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_062,20,31023937,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1141Ala/c.3422A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),27824,604,28589,"0,0211270069",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,47",Neutral,12,Damaging,"29,31","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_063,20,31023937,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1141Ala/c.3422A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),34036,702,34926,"0,0200996392",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,47",Neutral,12,Damaging,"29,43","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_064,20,31023937,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1141Ala/c.3422A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),38716,738,39664,"0,0186062929",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,47",Neutral,12,Damaging,"29,52","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_065,20,31023937,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1141Ala/c.3422A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),45772,890,46880,"0,0189846416",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,47",Neutral,12,Damaging,"29,62","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_066,20,31023937,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1141Ala/c.3422A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),69825,1262,71392,"0,0176770506",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,47",Neutral,12,Damaging,"29,66","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_067,20,31023937,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1141Ala/c.3422A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),64728,1112,66156,"0,0168087551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,47",Neutral,12,Damaging,"29,7","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_068,20,31023937,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1141Ala/c.3422A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),43562,939,44677,"0,0210175258",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,47",Neutral,12,Damaging,"29,36","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_069,20,31023937,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1141Ala/c.3422A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),45582,909,46698,"0,0194655017",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,47",Neutral,12,Damaging,"29,41","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_070,20,31023937,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1141Ala/c.3422A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),29627,623,30407,"0,0204887033",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,47",Neutral,12,Damaging,"29,4","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_071,20,31023937,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1141Ala/c.3422A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),22331,415,22868,"0,0181476299",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,47",Neutral,12,Damaging,"29,56","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_072,20,31023937,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1141Ala/c.3422A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),23931,499,24583,"0,0202985803",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,47",Neutral,12,Damaging,"29,56","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_073,20,31023937,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1141Ala/c.3422A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),29480,556,30167,"0,0184307356",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,47",Neutral,12,Damaging,"29,61","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_074,20,31023937,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1141Ala/c.3422A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),32254,546,32977,"0,0165569943",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,47",Neutral,12,Damaging,"29,64","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_075,20,31023937,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1141Ala/c.3422A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),41203,718,42111,"0,0170501769",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,47",Neutral,12,Damaging,"29,66","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_076,20,31023937,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1141Ala/c.3422A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),36406,796,37394,"0,0212868375",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,47",Neutral,12,Damaging,"29,35","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_077,20,31023937,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1141Ala/c.3422A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),46573,993,47815,"0,0207675416",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,47",Neutral,12,Damaging,"29,43","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_078,20,31023937,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1141Ala/c.3422A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),33823,718,34710,"0,0206856814",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,47",Neutral,12,Damaging,"29,29","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_079,20,31023937,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1141Ala/c.3422A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),22483,430,23052,"0,0186534791",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,47",Neutral,12,Damaging,"29,53","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_080,20,31023937,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1141Ala/c.3422A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),33513,681,34326,"0,019839189",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,47",Neutral,12,Damaging,"29,46","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_081,20,31023937,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1141Ala/c.3422A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),39685,747,40670,"0,0183673469",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,47",Neutral,12,Damaging,"29,6","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_082,20,31023937,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1141Ala/c.3422A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),58914,982,60186,"0,0163160868",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,47",Neutral,12,Damaging,"29,62","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_083,20,31023937,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1141Ala/c.3422A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),39871,884,40923,"0,0216015444",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,47",Neutral,12,Damaging,"29,23","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_084,20,31023937,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1141Ala/c.3422A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),39388,878,40438,"0,0217122509",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,47",Neutral,12,Damaging,"29,35","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_085,20,31023937,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1141Ala/c.3422A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),46657,936,47796,"0,0195832287",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,47",Neutral,12,Damaging,"29,46","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_086,20,31023937,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1141Ala/c.3422A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),40167,888,41205,"0,0215507827",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,47",Neutral,12,Damaging,"29,32","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_087,20,31023937,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1141Ala/c.3422A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),55914,1138,57376,"0,019834077",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,47",Neutral,12,Damaging,"29,54","14,69"
"low bq, low freq, many artifacts",UPN2_088,20,31023937,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1141Ala/c.3422A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),43894,752,44876,"0,0167572867",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,47",Neutral,12,Damaging,"29,66","14,99"
"low freq, many artifacts, many samples",UPN2_001,20,31023955,T,G,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu1147Arg/c.3440T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),17071,201,17362,"0,0115770073",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,82",Neutral,99,Tolerated,"32,43","30,83"
"low freq, many artifacts",UPN2_002,20,31023955,T,G,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu1147Arg/c.3440T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),22436,236,22766,"0,0103663358",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,82",Neutral,"0,099",Tolerated,"32,42","31,01"
"low freq, many artifacts, many samples",UPN2_003,20,31023955,T,G,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu1147Arg/c.3440T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),4205,47,4270,"0,0110070258",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,82",Neutral,99,Tolerated,"32,37",30
"low freq, many artifacts, many samples",UPN2_004,20,31023955,T,G,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu1147Arg/c.3440T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),5121,60,5208,"0,0115207373",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,82",Neutral,99,Tolerated,"32,48","31,33"
"low freq, many artifacts",UPN2_044,20,31023955,T,G,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu1147Arg/c.3440T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),7905,90,8032,"0,0112051793",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,82",Neutral,"0,099",Tolerated,"32,27","30,97"
"low freq, many artifacts, many samples",UPN2_005,20,31023955,T,G,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu1147Arg/c.3440T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),7195,81,7301,"0,0110943706",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,82",Neutral,99,Tolerated,"32,48","30,35"
"low freq, many artifacts, many samples",UPN2_006,20,31023955,T,G,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu1147Arg/c.3440T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),11453,165,11655,"0,0141570142",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,82",Neutral,99,Tolerated,"32,38","31,15"
"low freq, many artifacts, many samples",UPN2_061,20,31023955,T,G,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu1147Arg/c.3440T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),44609,456,45270,"0,010072896",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,82",Neutral,99,Tolerated,"32,02","28,77"
"low freq, many artifacts, many samples",UPN2_062,20,31023955,T,G,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu1147Arg/c.3440T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),39232,402,39739,"0,0101160069",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,82",Neutral,99,Tolerated,"31,98","29,48"
"low freq, many artifacts, many samples",UPN2_071,20,31023955,T,G,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu1147Arg/c.3440T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),31799,335,32243,"0,0103898521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,82",Neutral,99,Tolerated,"32,02","29,39"
"low freq, many artifacts",UPN2_083,20,31023955,T,G,missense_variant(MODERATE|MISSENSE|cTa/cGa|p.Leu1147Arg/c.3440T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),56216,572,57003,"0,0100345596",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,82",Neutral,99,Tolerated,"32,03","28,8"
"low freq, many artifacts",UPN2_044,20,31023979,T,A,missense_variant(MODERATE|MISSENSE|cTt/cAt|p.Leu1155His/c.3464T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),5308,86,5412,"0,0158906135",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,2",Neutral,"0,062",Tolerated,"34,99","33,76"
"low freq, many artifacts",UPN2_006,20,31023982,GA,G,frameshift_variant(HIGH||aac/|p.Asn1158fs/c.3473delA|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G|INFO_REALIGN_3_PRIME),7971,100,8105,"0,0123380629",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,41",NA
"low freq, many artifacts",UPN2_044,20,31023984,A,G,missense_variant(MODERATE|MISSENSE|Aaa/Gaa|p.Lys1157Glu/c.3469A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),5314,59,5397,"0,0109319993",0,0,0,0,1,0,0,1,2,NO,0,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"0,38",Neutral,1,Tolerated,"34,44","35,34"
"low freq, many artifacts",UPN2_044,20,31023998,G,A,missense_variant(MODERATE|MISSENSE|atG/atA|p.Met1161Ile/c.3483G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),5331,54,5396,"0,0100074129",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,08",Neutral,"0,43",Tolerated,"34,78","34,54"
"inspected, many artifacts",UPN2_044,20,31024012,GC,G,frameshift_variant(HIGH||ccc/|p.Ser1168fs/c.3501delC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G|INFO_REALIGN_3_PRIME),5294,88,5394,"0,0163144234",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,86",NA
"low bq, low freq, many artifacts, many samples",UPN2_014,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),33462,353,33874,"0,0104209718",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,06","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_016,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),20062,220,20320,"0,0108267717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,16","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_017,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),15007,153,15200,"0,0100657895",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,01","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_018,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),21878,233,22156,"0,0105163387",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,08","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_019,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),23990,255,24302,"0,0104929635",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,02","14,08"
"low bq, low freq, many artifacts, many samples",UPN2_021,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),23652,254,23960,"0,0106010017",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,07","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_022,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),34556,375,35008,"0,0107118373",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,03","14,19"
"low bq, low freq, many artifacts, many samples",UPN2_023,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),36071,369,36545,"0,0100971405",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"29,99","14,12"
"low bq, low freq, many artifacts, many samples",UPN2_025,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),38429,399,38902,"0,0102565421",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,09","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_026,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),41101,419,41632,"0,0100643736",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,02","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_089,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),24734,267,25057,"0,010655705",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,7","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_042,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),54814,625,55670,"0,0112268726",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,46","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_043,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),37619,458,38214,"0,0119851363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,4","14,12"
"low bq, low freq, many artifacts, many samples",UPN2_044,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),8016,95,8146,"0,0116621655",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,32","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_029,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),36827,373,37267,"0,010008855",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,09","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_030,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),32554,343,32958,"0,0104071849",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,09","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_031,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),23175,236,23459,"0,0100601049",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,08","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_045,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),49924,568,50672,"0,0112093464",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,35","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_032,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),13245,160,13420,"0,0119225037",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,09","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_046,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),44259,551,44941,"0,0122605193",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,45","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_034,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9973,118,10111,"0,0116704579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,09","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_047,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),67554,727,68530,"0,0106084926",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,39","14,2"
"low bq, low freq, many artifacts, many samples",UPN2_035,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),28500,307,28860,"0,0106375606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,08","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_036,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),28798,321,29210,"0,0109893872",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,11","14,19"
"low bq, low freq, many artifacts, many samples",UPN2_049,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),31918,349,32405,"0,0107699429",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,41","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_050,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),42391,499,43093,"0,0115796069",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,44","15,52"
"low bq, low freq, many artifacts, many samples",UPN2_051,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),34309,355,34805,"0,010199684",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,43","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_052,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),36044,433,36644,"0,0118163956",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,42","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_038,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),59062,631,59841,"0,0105446099",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,01","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_039,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),25893,270,26185,"0,0103112469",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,1","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_053,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),45828,565,46563,"0,0121340979",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,43","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_054,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),29913,370,30427,"0,0121602524",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,34","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_055,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),50968,571,51739,"0,0110361623",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,47","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_056,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),8961,95,9079,"0,0104637075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,45","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_090,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),21741,228,22008,"0,0103598691",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,62","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_057,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),46793,485,47487,"0,0102133215",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,45","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_058,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),41020,462,41671,"0,011086847",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,44","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_059,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),62794,692,63608,"0,0108791347",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,7","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_060,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),47960,665,48721,"0,0136491451",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,57","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_040,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),20866,217,21113,"0,0102780278",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,08","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_091,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),17860,227,18118,"0,0125289767",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,51","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_092,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),14169,159,14378,"0,0110585617",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,7","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_093,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),14999,153,15194,"0,0100697644",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,66","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_061,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),41365,589,42042,"0,0140097997",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,51","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_062,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),35925,475,36465,"0,0130261895",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,49","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_063,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),43116,543,43747,"0,0124122797",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,53","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_064,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),43759,513,44360,"0,0115644725",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,56","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_065,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),48637,645,49404,"0,013055623",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,65",15
"low bq, low freq, many artifacts, many samples",UPN2_066,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),67888,731,68722,"0,0106370595",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,69","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_067,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),66023,764,66931,"0,0114147406",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,63","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_068,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),49954,637,50670,"0,0125715413",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,56","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_069,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),55719,729,56528,"0,0128962638",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,53","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_070,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),34067,462,34605,"0,0133506719",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,55","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_071,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),29810,397,30256,"0,0131213644",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,38","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_072,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),32655,469,33184,"0,0141333173",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,37","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_073,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),37323,520,37907,"0,013717783",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,48","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_074,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),34962,455,35472,"0,0128270185",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,66","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_075,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),52078,768,52949,"0,0145045232",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,52","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_076,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),44356,572,45002,"0,0127105462",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,49","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_077,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),54551,711,55372,"0,0128404248",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,57","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_078,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),42216,586,42886,"0,0136641328",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,47","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_079,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),27742,373,28170,"0,0132410366",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,51","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_080,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),41930,599,42601,"0,0140607028",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,51","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_081,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),51122,783,52066,"0,0150386048",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,53","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_082,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),62732,777,63644,"0,012208535",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,62","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_083,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),51947,581,52655,"0,0110340898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,61","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_084,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),48542,603,49223,"0,0122503708",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,49","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_085,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),48014,586,48701,"0,0120326071",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,67","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_086,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),38190,412,38678,"0,0106520503",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,66","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_087,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),61880,818,62816,"0,01302216",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,6","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_088,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),49501,643,50249,"0,0127962746",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,62","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_095,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),23059,257,23352,"0,0110054813",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,6","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_096,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),25199,307,25552,"0,0120147151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,69","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_097,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),28246,338,28624,"0,0118082728",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,6","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_098,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),22900,250,23190,"0,0107805088",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,62","15,61"
"low bq, low freq, many artifacts, many samples",UPN2_099,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),12769,152,12936,"0,0117501546",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,68","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_100,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),19789,209,20023,"0,0104379963",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,75","14,1"
"low bq, low freq, many artifacts, many samples",UPN2_101,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),20966,237,21245,"0,011155566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,65","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_102,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),22230,245,22509,"0,0108845351",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,61","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_103,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),20757,217,21002,"0,0103323493",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,64","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_104,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),26204,300,26569,"0,0112913546",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,68","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_105,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),22541,232,22809,"0,0101714236",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,69","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_106,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),34833,452,35344,"0,0127885921",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,55","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_107,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),39439,492,40016,"0,012295082",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,64","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_108,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),33602,419,34086,"0,0122924368",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,65","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_109,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),31896,388,32349,"0,0119941884",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,61","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_110,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),33778,417,34252,"0,0121744716",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,57","14,66"
"low bq, low freq, many artifacts",UPN2_111,20,31024030,C,G,missense_variant(MODERATE|MISSENSE|gCt/gGt|p.Ala1172Gly/c.3515C>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),27821,326,28188,"0,0115652051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,01",Neutral,8,Damaging,"30,6","14,2"
"strandbias, many samples",UPN2_001,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),17460,1163,18688,"0,0622324486",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,55","31,63"
"strandbias, many samples",UPN2_014,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),31978,1830,33908,"0,0539695647",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,3","31,68"
"strandbias, many samples",UPN2_015,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),38974,2051,41167,"0,0498214589",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,31","31,79"
"strandbias, many samples",UPN2_016,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),19169,1097,20344,"0,0539225324",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,29","31,71"
"strandbias, many samples",UPN2_017,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),14251,918,15225,"0,0602955665",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,28","31,63"
"strandbias, many samples",UPN2_018,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),20847,1265,22191,"0,0570050922",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,33","31,65"
"strandbias, many samples",UPN2_019,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),22869,1396,24345,"0,0573423701",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,32","31,78"
"strandbias, many samples",UPN2_020,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),20217,1159,21435,"0,0540704455",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,35","31,64"
"strandbias, many samples",UPN2_021,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),22528,1373,23963,"0,0572966657",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,33","31,73"
"strandbias, many samples",UPN2_002,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),21027,1760,22839,"0,0770611673",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,52","31,62"
"strandbias, many samples",UPN2_003,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4245,317,4579,"0,0692290893",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,56","31,71"
"strandbias, many samples",UPN2_022,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),33106,1864,35056,"0,0531720675",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,33","31,63"
"strandbias, many samples",UPN2_023,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),34561,1904,36585,"0,0520431871",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,34","31,59"
"strandbias, many samples",UPN2_041,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),27976,1508,29606,"0,0509356212",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"31,94","31,52"
"strandbias, many samples",UPN2_024,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),15650,823,16514,"0,0498365024",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,29","31,79"
"strandbias, many samples",UPN2_025,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),36581,2245,38964,"0,0576172878",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,29","31,68"
"strandbias, many samples",UPN2_026,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),39208,2323,41656,"0,0557662762",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,34","31,69"
"strandbias, many samples",UPN2_004,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4507,417,4947,"0,0842935112",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,34","31,57"
"strandbias, many samples",UPN2_027,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),39520,2639,42299,"0,0623891818",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,32","31,74"
"strandbias, many samples",UPN2_089,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),24485,586,25101,"0,0233456834",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,28","31,5"
"strandbias, many samples",UPN2_042,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),53706,1728,55685,"0,0310316961",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,96","31,46"
"strandbias, many samples",UPN2_028,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),28297,1720,30098,"0,0571466543",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,33","31,72"
"strandbias, many samples",UPN2_043,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),37061,1067,38296,"0,0278619177",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,02","31,44"
"inspected, strandbias, many samples",UPN2_044,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),7862,270,8148,"0,0331369661",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,95","31,48"
"strandbias, many samples",UPN2_029,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),35106,2116,37345,"0,0566608649",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,29","31,6"
"strandbias, many samples",UPN2_030,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),31116,1783,33002,"0,0540270287",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,32","31,63"
"strandbias, many samples",UPN2_031,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),22146,1283,23488,"0,0546236376",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,23","31,71"
"strandbias, many samples",UPN2_005,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6730,629,7384,"0,085184182",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,57","31,45"
"strandbias, many samples",UPN2_045,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),49559,1039,50782,"0,0204600055",0,0,0,0,1,1,0,1,3,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,02","31,34"
"strandbias, many samples",UPN2_032,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),12679,697,13415,"0,0519567648",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,26","31,72"
"strandbias, many samples",UPN2_046,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),43126,1728,45008,"0,0383931745",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,97","31,5"
"strandbias, many samples",UPN2_033,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),24725,1471,26269,"0,0559975637",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,24","31,64"
"strandbias, many samples",UPN2_034,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),9605,487,10132,"0,0480655349",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,35","31,55"
"strandbias, many samples",UPN2_047,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),66041,2304,68607,"0,033582579",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,94","31,66"
"strandbias, many samples",UPN2_048,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),43310,2409,45896,"0,0524882343",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,65","31,41"
"strandbias, many samples",UPN2_035,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),27139,1681,28912,"0,058141948",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,2","31,72"
"strandbias, many samples",UPN2_036,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),27495,1654,29238,"0,0565702168",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,26","31,72"
"strandbias, many samples",UPN2_006,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),11905,769,12719,"0,060460728",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,65","31,6"
"strandbias, many samples",UPN2_049,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),31356,937,32460,"0,028866297",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,99","31,54"
"strandbias, many samples",UPN2_050,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),42277,775,43193,"0,0179427222",0,0,0,0,1,1,0,1,3,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,97","31,34"
"strandbias, many samples",UPN2_037,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),52009,2848,55028,"0,0517554699",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,31","31,72"
"strandbias, many samples",UPN2_051,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),33818,905,34855,"0,0259647109",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,03","31,56"
"strandbias, many samples",UPN2_052,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),35848,796,36763,"0,0216522047",0,0,0,0,1,1,0,1,3,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,95","31,59"
"strandbias, many samples",UPN2_038,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),56706,3029,59948,"0,0505271235",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,35","31,7"
"strandbias, many samples",UPN2_039,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),24734,1443,26246,"0,0549798064",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,28","31,71"
"strandbias, many samples",UPN2_053,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),44876,1621,46657,"0,034742911",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,99","31,5"
"strandbias, many samples",UPN2_054,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),29562,824,30486,"0,0270288001",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,98","31,56"
"strandbias, many samples",UPN2_007,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),52435,3449,56041,"0,0615442265",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,46","31,62"
"strandbias, many samples",UPN2_008,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),74685,4673,79569,"0,058728902",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,56","31,67"
"strandbias, many samples",UPN2_009,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),57860,3442,61504,"0,0559638398",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,55","31,68"
"strandbias, many samples",UPN2_010,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),42067,2660,44851,"0,0593074848",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,55","31,63"
"inspected, strandbias, many samples",UPN2_011,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),50183,3216,53561,"0,0600436885",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,53","31,57"
"strandbias, many samples",UPN2_055,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),50112,1566,51859,"0,0301972657",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,01","31,57"
"strandbias, many samples",UPN2_056,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),8724,313,9067,"0,0345207897",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,86","31,76"
"strandbias, many samples",UPN2_090,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),21597,402,22023,"0,0182536439",0,0,0,0,1,1,0,1,3,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,21","31,62"
"strandbias, many samples",UPN2_057,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),45927,1452,47572,"0,0305221559",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,97","31,7"
"strandbias, many samples",UPN2_058,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),39874,1695,41746,"0,0406026925",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,96","31,52"
"strandbias, many samples",UPN2_059,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),58263,5125,63567,"0,080623594",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,59","31,59"
"strandbias, many samples",UPN2_012,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),25664,1612,27337,"0,0589676995",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,56","31,68"
"strandbias, many samples",UPN2_060,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),45192,3500,48843,"0,0716581701",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,78","31,46"
"strandbias, many samples",UPN2_040,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),20049,1078,21181,"0,0508946698",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,31","31,71"
"strandbias, many samples",UPN2_013,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),14612,1009,15670,"0,0643905552",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,48","31,69"
"strandbias, many samples",UPN2_091,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),17678,434,18140,"0,0239250276",0,0,0,0,1,1,0,1,3,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,32","31,69"
"strandbias, many samples",UPN2_092,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),14056,287,14371,"0,0199707745",0,0,0,0,1,1,0,1,3,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,31","31,54"
"strandbias, many samples",UPN2_093,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),14852,335,15199,"0,0220409237",0,0,0,0,1,1,0,1,3,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,26","31,56"
"strandbias, many samples",UPN2_061,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),38923,3141,42180,"0,0744665718",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,81","31,55"
"strandbias, many samples",UPN2_062,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),33680,2743,36534,"0,0750807467",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,82","31,72"
"strandbias, many samples",UPN2_063,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),40217,3438,43800,"0,0784931507",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,85","31,51"
"strandbias, many samples",UPN2_064,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),40279,3920,44351,"0,0883858312",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,73","31,56"
"strandbias, many samples",UPN2_065,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),45297,3861,49319,"0,0782862588",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,66","31,57"
"strandbias, many samples",UPN2_066,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),62362,6123,68695,"0,0891331247",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,59","31,53"
"strandbias, many samples",UPN2_067,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),60858,5933,66991,"0,0885641355",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,63","31,55"
"strandbias, many samples",UPN2_068,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),46668,3919,50728,"0,0772551648",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,73","31,68"
"strandbias, many samples",UPN2_069,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),52401,4068,56635,"0,0718283747",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,75","31,6"
"strandbias, many samples",UPN2_070,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),31826,2698,34611,"0,0779520962",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,69","31,56"
"strandbias, many samples",UPN2_071,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),28035,2124,30275,"0,0701568951",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,79","31,55"
"strandbias, many samples",UPN2_072,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),30897,2285,33264,"0,0686928812",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,84","31,59"
"strandbias, many samples",UPN2_073,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),35247,2541,37920,"0,0670094937",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,83","31,47"
"strandbias, many samples",UPN2_074,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),32440,2911,35452,"0,0821110234",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,72","31,56"
"strandbias, many samples",UPN2_075,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),49281,3595,53027,"0,0677956513",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,81","31,56"
"strandbias, many samples",UPN2_076,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),41643,3224,44999,"0,0716460366",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,77","31,56"
"strandbias, many samples",UPN2_077,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),51507,3823,55480,"0,0689077145",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,73","31,57"
"strandbias, many samples",UPN2_078,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),39831,2969,42928,"0,0691623183",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,79","31,59"
"inspected, strandbias, many samples",UPN2_079,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),26175,1957,28225,"0,0693356953",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,82","31,71"
"strandbias, many samples",UPN2_080,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),39578,2893,42621,"0,0678773375",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,81","31,55"
"strandbias, many samples",UPN2_081,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),48794,3128,52092,"0,0600476081",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,83","31,6"
"strandbias, many samples",UPN2_082,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),58918,4508,63625,"0,0708526523",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,65","31,53"
"strandbias, many samples",UPN2_083,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),48685,3853,52729,"0,0730717442",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,71","31,63"
"strandbias, many samples",UPN2_084,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),45940,3107,49196,"0,0631555411",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,78","31,62"
"strandbias, many samples",UPN2_085,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),44889,3682,48705,"0,0755979879",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,63","31,53"
"strandbias, many samples",UPN2_086,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),35395,3171,38678,"0,0819845907",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,54","31,6"
"strandbias, many samples",UPN2_087,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),58140,4578,62915,"0,0727648415",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,69","31,47"
"strandbias, many samples",UPN2_088,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),45918,4278,50323,"0,08501083",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"32,76","31,61"
"strandbias, many samples",UPN2_094,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),27159,526,27720,"0,018975469",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,29","31,64"
"strandbias, many samples",UPN2_095,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),22813,548,23398,"0,0234208052",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,31","31,57"
"strandbias, many samples",UPN2_096,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),25097,455,25595,"0,0177769096",0,0,0,0,1,1,0,1,3,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,31","31,83"
"strandbias, many samples",UPN2_097,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),28050,685,28769,"0,0238103514",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,3","31,67"
"strandbias, many samples",UPN2_098,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),22617,538,23196,"0,0231936541",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,29","31,6"
"strandbias, many samples",UPN2_099,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),12613,302,12933,"0,0233511173",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,29","31,74"
"strandbias, many samples",UPN2_100,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),19642,365,20039,"0,0182144818",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,3","31,59"
"strandbias, many samples",UPN2_101,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),20869,368,21268,"0,0173029904",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,28","31,76"
"strandbias, many samples",UPN2_102,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),22035,460,22538,"0,0204099743",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,22","31,68"
"strandbias, many samples",UPN2_103,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),20574,444,21041,"0,0211016587",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,29","31,59"
"strandbias, many samples",UPN2_104,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),25998,575,26593,"0,0216222314",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,27","31,63"
"strandbias, many samples",UPN2_105,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),22390,485,22898,"0,0211808892",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,27","31,7"
"strandbias, many samples",UPN2_106,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),34751,586,35392,"0,0165574141",0,0,0,0,1,1,0,1,3,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,27","31,53"
"strandbias, many samples",UPN2_107,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),39291,733,40099,"0,0182797576",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,27","31,59"
"strandbias, many samples",UPN2_108,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),33474,605,34131,"0,0177258211",0,0,0,0,1,1,0,1,3,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,26","31,66"
"strandbias, many samples",UPN2_109,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),31853,505,32408,"0,0155825722",0,0,0,0,1,1,0,1,3,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,21","31,67"
"strandbias, many samples",UPN2_110,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),33894,435,34372,"0,0126556499",0,0,0,0,1,1,0,1,3,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,28","31,63"
"strandbias, many samples",UPN2_111,20,31024033,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1173Ser/c.3518T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),27642,544,28226,"0,0192730107",0,0,0,0,1,1,0,0,2,NO,NO,COSM4385129,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,"8,24E-006",NO,NO,"-0,69",Neutral,"0,255",Tolerated,"33,22","31,76"
"low bq, low freq, many artifacts",UPN2_041,20,31024058,C,A,missense_variant(MODERATE|MISSENSE|agC/agA|p.Ser1181Arg/c.3543C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),8017,92,8150,"0,0112883436",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,64",Neutral,66,Tolerated,"32,73","26,84"
"low bq, low freq, many artifacts",UPN2_041,20,31024061,T,A,stop_gained(HIGH|NONSENSE|tgT/tgA|p.Cys1182*/c.3546T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),7962,90,8147,"0,0110470112",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,03","17,68"
"low freq, many artifacts",UPN2_072,20,31024061,T,A,stop_gained(HIGH|NONSENSE|tgT/tgA|p.Cys1182*/c.3546T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),20637,392,21136,"0,0185465556",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,84","30,67"
"low freq, many artifacts",UPN2_056,20,31024063,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu1183Gly/c.3548A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),5525,70,5613,"0,0124710493",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,87",Neutral,"0,434",Tolerated,"34,26","32,7"
"low bq, low freq, many artifacts",UPN2_041,20,31024064,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu1183Asp/c.3549A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),7949,120,8145,"0,014732965",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,313,Tolerated,"29,88","15,95"
"low bq, low freq, many artifacts, many samples",UPN2_041,20,31024065,A,G,missense_variant(MODERATE|MISSENSE|Aca/Gca|p.Thr1184Ala/c.3550A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),7898,85,8144,"0,0104371316",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,67",Neutral,1,Tolerated,"28,91","20,69"
"low freq, many artifacts, many samples",UPN2_056,20,31024065,A,G,missense_variant(MODERATE|MISSENSE|Aca/Gca|p.Thr1184Ala/c.3550A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),5521,60,5613,"0,0106894709",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,67",Neutral,1,Tolerated,"32,23","31,55"
"low bq, low freq, many artifacts, many samples",UPN2_041,20,31024071,A,T,missense_variant(MODERATE|MISSENSE|Act/Tct|p.Thr1186Ser/c.3556A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),7939,104,8136,"0,0127826942",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,32",Neutral,324,Tolerated,"30,21","19,84"
"low bq, low freq, many artifacts, many samples",UPN2_041,20,31024087,T,G,missense_variant(MODERATE|MISSENSE|aTt/aGt|p.Ile1191Ser/c.3572T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),7967,83,8117,"0,0102254528",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,02",Neutral,26,Damaging,"30,38","14,78"
"low freq, many artifacts",UPN2_056,20,31024089,G,A,missense_variant(MODERATE|MISSENSE|Gag/Aag|p.Glu1192Lys/c.3574G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),5513,62,5603,"0,0110655006",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,"0,223",Tolerated,"32,8","34,16"
"low bq, low freq, many artifacts, many samples",UPN2_041,20,31024090,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1192Ala/c.3575A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),7944,102,8114,"0,0125708652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,19,Damaging,"29,55","14,88"
"low bq, many samples",UPN2_041,20,31024095,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1194Pro/c.3580A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),7669,230,8100,"0,0283950617",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,"0,01",Damaging,"27,03","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_059,20,31024095,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1194Pro/c.3580A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),30058,465,30682,"0,0151554657",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,"0,01",Damaging,"29,87","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_060,20,31024095,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1194Pro/c.3580A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),28338,498,28977,"0,0171860441",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,"0,01",Damaging,"29,72","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_061,20,31024095,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1194Pro/c.3580A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),25571,414,26138,"0,0158390083",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,"0,01",Damaging,"29,69","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_062,20,31024095,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1194Pro/c.3580A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),21919,342,22393,"0,0152726298",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,"0,01",Damaging,"29,56","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_063,20,31024095,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1194Pro/c.3580A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),25920,431,26483,"0,0162745912",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,"0,01",Damaging,"29,85","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_064,20,31024095,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1194Pro/c.3580A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),24206,368,24705,"0,0148957701",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,"0,01",Damaging,"29,82","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_065,20,31024095,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1194Pro/c.3580A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),25599,419,26148,"0,0160241701",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,"0,01",Damaging,"29,84","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_066,20,31024095,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1194Pro/c.3580A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),32643,538,33371,"0,0161217824",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,"0,01",Damaging,"29,75","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_067,20,31024095,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1194Pro/c.3580A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),33566,511,34273,"0,0149096957",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,"0,01",Damaging,"29,8","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_068,20,31024095,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1194Pro/c.3580A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),28087,457,28696,"0,0159255645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,"0,01",Damaging,"29,68","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_069,20,31024095,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1194Pro/c.3580A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),32824,552,33551,"0,0164525648",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,"0,01",Damaging,"29,73","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_070,20,31024095,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1194Pro/c.3580A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),19180,297,19586,"0,0151638926",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,"0,01",Damaging,"29,64","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_071,20,31024095,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1194Pro/c.3580A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),18592,292,18979,"0,015385426",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,"0,01",Damaging,"29,8","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_072,20,31024095,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1194Pro/c.3580A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),20661,319,21086,"0,0151285213",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,"0,01",Damaging,"29,8","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_073,20,31024095,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1194Pro/c.3580A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),22492,364,22993,"0,0158309051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,"0,01",Damaging,"29,85","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_074,20,31024095,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1194Pro/c.3580A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),18730,316,19136,"0,0165133779",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,"0,01",Damaging,"29,74","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_075,20,31024095,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1194Pro/c.3580A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),31488,478,32116,"0,0148835471",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,"0,01",Damaging,"29,86","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_076,20,31024095,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1194Pro/c.3580A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),25919,454,26499,"0,017132722",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,"0,01",Damaging,"29,71","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_077,20,31024095,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1194Pro/c.3580A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),31092,490,31763,"0,0154267544",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,"0,01",Damaging,"29,68","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_078,20,31024095,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1194Pro/c.3580A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),25184,432,25759,"0,0167708374",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,"0,01",Damaging,"29,64","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_079,20,31024095,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1194Pro/c.3580A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16428,278,16796,"0,0165515599",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,"0,01",Damaging,"29,77","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_080,20,31024095,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1194Pro/c.3580A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),25052,411,25603,"0,0160528063",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,"0,01",Damaging,"29,91","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_081,20,31024095,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1194Pro/c.3580A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),31321,463,31963,"0,0144854989",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,"0,01",Damaging,"29,97","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_082,20,31024095,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1194Pro/c.3580A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),33188,481,33837,"0,0142152082",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,"0,01",Damaging,"29,73","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_083,20,31024095,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1194Pro/c.3580A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),31779,516,32463,"0,0158950189",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,"0,01",Damaging,"29,68","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_084,20,31024095,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1194Pro/c.3580A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),28625,454,29212,"0,0155415583",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,"0,01",Damaging,"29,76","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_085,20,31024095,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1194Pro/c.3580A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),24495,391,25056,"0,0156050447",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,"0,01",Damaging,"29,73","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_086,20,31024095,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1194Pro/c.3580A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),17921,275,18306,"0,015022397",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,"0,01",Damaging,"29,64","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_087,20,31024095,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1194Pro/c.3580A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),33847,519,34523,"0,015033456",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,"0,01",Damaging,"29,87","14,76"
"low bq, low freq, many artifacts",UPN2_088,20,31024095,A,C,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr1194Pro/c.3580A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),27522,455,28123,"0,0161789283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,"0,01",Damaging,"29,8","14,64"
"low freq, many artifacts",UPN2_036,20,31024112,A,AC,frameshift_variant(HIGH||caa/cCaa|p.Gln1201fs/c.3601dupC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|AC|INFO_REALIGN_3_PRIME),23760,289,23877,"0,0121036981",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,99",NA
"low bq, low freq, many artifacts, many samples",UPN2_085,20,31024147,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1211Ala/c.3632A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),39369,400,39974,"0,0100065042",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,3,Damaging,"31,49","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_086,20,31024147,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1211Ala/c.3632A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),30704,325,31148,"0,0104340568",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,03",Neutral,3,Damaging,"31,1","15,81"
"low freq, many artifacts",UPN2_044,20,31024235,T,A,stop_gained(HIGH|NONSENSE|tgT/tgA|p.Cys1240*/c.3720T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),7284,78,7394,"0,0105490939",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,47","33,22"
"low freq, many artifacts",UPN2_044,20,31024252,T,A,missense_variant(MODERATE|MISSENSE|gTc/gAc|p.Val1246Asp/c.3737T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),3621,51,3677,"0,0138700027",0,0,0,0,1,0,0,1,2,NO,NO,COSM1025734,endometrium,1,NO,NO,NO,NO,NO,NO,"-1,02",Neutral,"0,05",Damaging,"33,42","35,25"
"low freq, many artifacts",UPN2_044,20,31024255,G,A,missense_variant(MODERATE|MISSENSE|cGt/cAt|p.Arg1247His/c.3740G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),3623,44,3678,"0,0119630234",0,0,0,0,1,0,0,1,2,NO,NO,COSM4663895,large_intestine,1,NO,NO,NO,"2,47E-005",NO,NO,"1,38",Neutral,"0,586",Tolerated,"34,88","33,75"
"low freq, many artifacts, many samples",UPN2_044,20,31024304,AG,A,frameshift_variant(HIGH||gga/|p.Gly1264fs/c.3791delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),7605,90,7714,"0,0116670988",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,98",NA
"low bq, low freq, many artifacts, many samples",UPN2_055,20,31024335,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1274Ile/c.3820T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),25512,269,25909,"0,0103824926",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,83",Neutral,3,Damaging,"31,8","16,9"
"low bq, low freq, many artifacts",UPN2_058,20,31024335,T,A,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe1274Ile/c.3820T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),18674,220,19020,"0,0115667718",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,83",Neutral,3,Damaging,"31,93","18,11"
"low freq, many artifacts",UPN2_044,20,31024339,C,T,missense_variant(MODERATE|MISSENSE|tCa/tTa|p.Ser1275Leu/c.3824C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4247,55,4325,"0,012716763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,1,Tolerated,"33,88","32,71"
"low bq, low freq, many artifacts",UPN2_041,20,31024348,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn1278Thr/c.3833A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3154,49,3222,"0,0152079454",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,07",Neutral,5,Damaging,"28,49","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_041,20,31024354,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile1280Ser/c.3839T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3142,55,3225,"0,0170542636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,2,Damaging,"29,03","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_059,20,31024354,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile1280Ser/c.3839T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),33614,506,34277,"0,0147620854",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,2,Damaging,"30,78","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_060,20,31024354,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile1280Ser/c.3839T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),34070,504,34723,"0,0145148749",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,2,Damaging,"30,76","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_061,20,31024354,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile1280Ser/c.3839T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),28745,409,29270,"0,0139733516",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,2,Damaging,"30,63","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_062,20,31024354,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile1280Ser/c.3839T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),25823,423,26364,"0,0160446063",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,2,Damaging,"30,57","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_063,20,31024354,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile1280Ser/c.3839T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),27262,425,27853,"0,0152586795",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,2,Damaging,"30,76","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_064,20,31024354,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile1280Ser/c.3839T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),29166,465,29767,"0,0156213256",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,2,Damaging,"30,66","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_065,20,31024354,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile1280Ser/c.3839T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),31186,509,31827,"0,0159927106",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,2,Damaging,"30,73","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_066,20,31024354,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile1280Ser/c.3839T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),33792,482,34437,"0,0139965735",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,2,Damaging,"30,8","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_067,20,31024354,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile1280Ser/c.3839T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),34323,474,34956,"0,0135599039",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,2,Damaging,"30,9",15
"low bq, low freq, many artifacts, many samples",UPN2_068,20,31024354,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile1280Ser/c.3839T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),27107,500,27737,"0,0180264628",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,2,Damaging,"30,59","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_069,20,31024354,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile1280Ser/c.3839T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),26799,413,27355,"0,0150977883",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,2,Damaging,"30,64","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_070,20,31024354,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile1280Ser/c.3839T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),20132,326,20554,"0,0158606597",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,2,Damaging,"30,49","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_071,20,31024354,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile1280Ser/c.3839T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),20610,364,21134,"0,0172234314",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,2,Damaging,"30,73","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_072,20,31024354,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile1280Ser/c.3839T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),25179,395,25709,"0,0153642693",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,2,Damaging,"30,76","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_073,20,31024354,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile1280Ser/c.3839T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),20933,341,21371,"0,0159562023",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,2,Damaging,"30,84","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_074,20,31024354,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile1280Ser/c.3839T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),18084,242,18386,"0,0131621886",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,2,Damaging,"30,85","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_075,20,31024354,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile1280Ser/c.3839T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),34882,458,35517,"0,0128952333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,2,Damaging,"30,89","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_076,20,31024354,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile1280Ser/c.3839T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),31986,545,32646,"0,0166942351",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,2,Damaging,"30,56","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_077,20,31024354,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile1280Ser/c.3839T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),34600,555,35326,"0,0157108079",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,2,Damaging,"30,68","15,31"
"low bq, low freq, many artifacts, many samples",UPN2_078,20,31024354,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile1280Ser/c.3839T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),26419,430,26984,"0,0159353691",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,2,Damaging,"30,61","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_079,20,31024354,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile1280Ser/c.3839T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),19110,321,19542,"0,016426159",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,2,Damaging,"30,73","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_080,20,31024354,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile1280Ser/c.3839T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),28559,468,29178,"0,0160394818",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,2,Damaging,"30,66","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_081,20,31024354,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile1280Ser/c.3839T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),37215,574,37990,"0,0151092393",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,2,Damaging,"30,74","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_082,20,31024354,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile1280Ser/c.3839T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),32198,454,32853,"0,0138191337",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,2,Damaging,"30,8","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_083,20,31024354,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile1280Ser/c.3839T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),36545,656,37358,"0,0175598265",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,2,Damaging,"30,5","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_084,20,31024354,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile1280Ser/c.3839T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),32802,598,33568,"0,0178145853",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,2,Damaging,"30,59","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_085,20,31024354,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile1280Ser/c.3839T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),27155,438,27718,"0,0158020059",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,2,Damaging,"30,7","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_086,20,31024354,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile1280Ser/c.3839T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),18627,311,19007,"0,0163623928",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,2,Damaging,"30,66","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_087,20,31024354,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile1280Ser/c.3839T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),35981,541,36733,"0,0147279013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,2,Damaging,"30,72","14,97"
"low bq, low freq, many artifacts",UPN2_088,20,31024354,T,G,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile1280Ser/c.3839T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),29306,371,29827,"0,0124383947",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,2,Damaging,"30,9","14,85"
"low freq, many artifacts",UPN2_056,20,31024360,T,C,missense_variant(MODERATE|MISSENSE|tTt/tCt|p.Phe1282Ser/c.3845T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),5761,83,5900,"0,0140677966",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,"0,109",Tolerated,"33,55","34,54"
"inspected, many artifacts",UPN2_040,20,31024365,C,T,missense_variant(MODERATE|MISSENSE|Cca/Tca|p.Pro1284Ser/c.3850C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16522,398,16975,"0,0234462445",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,227",Tolerated,"34,45","32,41"
"low bq, low freq, many artifacts, many samples",UPN2_060,20,31024394,T,G,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp1293Glu/c.3879T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),34135,381,34684,"0,0109848922",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,55,Tolerated,"29,83","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_061,20,31024394,T,G,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp1293Glu/c.3879T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),28825,313,29246,"0,0107023183",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,55,Tolerated,"29,74","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_062,20,31024394,T,G,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp1293Glu/c.3879T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),25917,297,26332,"0,0112790521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,55,Tolerated,"29,58","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_068,20,31024394,T,G,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp1293Glu/c.3879T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),27285,313,27709,"0,0112959688",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,55,Tolerated,"29,55","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_069,20,31024394,T,G,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp1293Glu/c.3879T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),26935,302,27335,"0,0110481068",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,55,Tolerated,"29,59","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_074,20,31024394,T,G,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp1293Glu/c.3879T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),18061,195,18367,"0,0106168672",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,55,Tolerated,"29,84","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_076,20,31024394,T,G,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp1293Glu/c.3879T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),32161,346,32623,"0,0106060142",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,55,Tolerated,"29,53","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_077,20,31024394,T,G,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp1293Glu/c.3879T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),34743,362,35295,"0,0102564103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,55,Tolerated,"29,68","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_080,20,31024394,T,G,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp1293Glu/c.3879T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),28722,305,29151,"0,0104627629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,55,Tolerated,"29,79","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_081,20,31024394,T,G,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp1293Glu/c.3879T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),37372,391,37957,"0,0103011302",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,55,Tolerated,"29,85","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_083,20,31024394,T,G,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp1293Glu/c.3879T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),36723,405,37328,"0,0108497643",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,55,Tolerated,"29,49","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_084,20,31024394,T,G,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp1293Glu/c.3879T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),32967,401,33542,"0,0119551607",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,55,Tolerated,"29,53","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_085,20,31024394,T,G,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp1293Glu/c.3879T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),27279,308,27694,"0,0111215426",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,55,Tolerated,"29,77","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_086,20,31024394,T,G,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp1293Glu/c.3879T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),18678,210,18999,"0,0110532133",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,55,Tolerated,"29,8","15,26"
"low bq, low freq, many artifacts",UPN2_087,20,31024394,T,G,missense_variant(MODERATE|MISSENSE|gaT/gaG|p.Asp1293Glu/c.3879T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),36143,373,36701,"0,0101632108",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,7",Neutral,55,Tolerated,"29,83","14,7"
"low bq, low freq, many artifacts",UPN2_046,20,31024405,T,A,missense_variant(MODERATE|MISSENSE|gTt/gAt|p.Val1297Asp/c.3890T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),44042,483,44820,"0,0107764391",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,87",Neutral,38,Damaging,"30,69","20,93"
"low freq, many artifacts",UPN2_044,20,31024467,A,G,missense_variant(MODERATE|MISSENSE|Agg/Ggg|p.Arg1318Gly/c.3952A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),5684,83,5783,"0,0143524122",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,02",Neutral,"0,001",Damaging,"34,82","34,7"
"low freq, many artifacts",UPN2_044,20,31024488,C,T,missense_variant(MODERATE|MISSENSE|Ctt/Ttt|p.Leu1325Phe/c.3973C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5697,81,5781,"0,0140114167",0,0,0,0,1,1,0,0,2,"0,0465","0,003",NO,NO,O,rs6057581,rs6057581,NO,"0,008937",NO,YES,"-1,43",Neutral,"0,007",Damaging,"32,78","32,2"
"low freq, many artifacts",UPN2_044,20,31024504,C,T,missense_variant(MODERATE|MISSENSE|cCt/cTt|p.Pro1330Leu/c.3989C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1656,29,1685,"0,0172106825",0,0,0,0,1,0,0,1,2,NO,0,NO,NA,NA,NO,rs201002256,NO,"8,24E-006",NO,NO,"-4,31",Deleterious,"0,003",Damaging,"34,77","34,69"
"low freq, many artifacts",UPN2_044,20,31024512,T,A,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe1333Ile/c.3997T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),1650,27,1685,"0,0160237389",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,65",Neutral,"0,006",Damaging,"34,66","33,59"
"low freq, many artifacts",UPN2_044,20,31024515,C,T,missense_variant(MODERATE|MISSENSE|Ccc/Tcc|p.Pro1334Ser/c.4000C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1654,24,1685,"0,0142433234",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,04",Deleterious,"0,186",Tolerated,"35,01",36
"low bq, low freq, many artifacts, many samples",UPN2_014,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),13016,163,13380,"0,0121823617",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,13","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_015,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),19119,299,19689,"0,0151861445",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,12","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_016,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),8687,105,8922,"0,0117686617",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,13","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_017,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6801,93,6995,"0,0132952109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,14","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_018,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),10056,157,10350,"0,0151690821",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,15","15,25"
"low bq, low freq, many artifacts, many samples",UPN2_019,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),9831,158,10140,"0,015581854",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,11","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_020,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),8372,104,8602,"0,0120902116",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,16","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_021,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),10313,122,10574,"0,0115377341",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,19","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_003,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),2127,26,2203,"0,0118020881",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"30,17","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_022,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),13202,151,13552,"0,0111422668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,19","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_023,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),13305,205,13697,"0,014966781",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,16","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_024,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),7015,91,7226,"0,0125934127",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,06","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_025,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16988,220,17481,"0,0125850924",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,23","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_026,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16295,258,16807,"0,0153507467",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,18","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_027,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16052,219,16520,"0,0132566586",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,1","15,37"
"low bq, low freq, many artifacts, many samples",UPN2_042,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),25557,293,26521,"0,0110478489",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"30,29","15,25"
"low bq, low freq, many artifacts, many samples",UPN2_028,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),11024,153,11330,"0,0135039718",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,14","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_043,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),15604,169,16144,"0,0104682854",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"30,38","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_044,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3207,37,3309,"0,0111816259",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"30,34",14
"low bq, low freq, many artifacts, many samples",UPN2_029,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),13602,199,14053,"0,0141606774",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,18","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_030,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),14385,161,14764,"0,0109049038",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,21","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_031,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),10642,147,10935,"0,0134430727",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,13","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_045,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),21020,245,21753,"0,0112628143",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"30,26","15,54"
"low bq, low freq, many artifacts, many samples",UPN2_032,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4675,54,4823,"0,0111963508",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,25","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_046,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),19923,227,20635,"0,0110007269",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"30,37","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_033,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),11737,138,12068,"0,0114352005",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,11","15,4"
"low bq, low freq, many artifacts, many samples",UPN2_034,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4005,60,4118,"0,0145701797",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,39","15,75"
"low bq, low freq, many artifacts, many samples",UPN2_047,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),28433,332,29502,"0,0112534743",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"30,29","15,52"
"low bq, low freq, many artifacts, many samples",UPN2_035,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),12389,163,12755,"0,0127793022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,16","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_036,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),14227,198,14673,"0,013494173",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,08","16,33"
"low bq, low freq, many artifacts, many samples",UPN2_049,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),12647,134,13085,"0,0102407337",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"30,15","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_050,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),18733,227,19447,"0,0116727516",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"30,24","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_037,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),23346,329,24049,"0,0136804025",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,15","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_052,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),15407,165,15969,"0,0103325193",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"30,22","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_038,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),25589,350,26335,"0,0132902981",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,14","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_039,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),13440,175,13828,"0,0126554816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,13","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_054,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),14719,195,15285,"0,0127576055",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"30,19","16,24"
"low bq, low freq, many artifacts, many samples",UPN2_055,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),25595,282,26541,"0,0106250706",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"30,25","15,77"
"low bq, low freq, many artifacts, many samples",UPN2_056,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),5146,60,5345,"0,0112254443",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"30,17","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_057,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16455,175,17060,"0,0102579132",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"30,32","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_058,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),17901,199,18534,"0,0107370238",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"30,22","15,69"
"low bq, low freq, many artifacts, many samples",UPN2_059,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),23118,300,23825,"0,0125918153",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,57","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_060,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),19722,294,20412,"0,0144032922",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,49","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_040,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),10105,123,10387,"0,0118417252",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,26","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_061,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),17199,276,17777,"0,0155256792",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,59","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_062,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),14290,237,14777,"0,0160384381",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,51","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_063,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16822,228,17361,"0,0131328841",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,67","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_064,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16585,262,17154,"0,0152734056",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,56","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_065,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),18307,254,18900,"0,0134391534",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,44","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_066,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),21583,386,22379,"0,0172483132",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,49","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_067,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),20187,263,20795,"0,012647271",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,58","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_068,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),17358,250,17908,"0,0139602412",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,6","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_069,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),23104,383,23900,"0,0160251046",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,66","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_070,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),13550,205,13941,"0,0147048275",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,47","15,6"
"low bq, low freq, many artifacts, many samples",UPN2_071,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),13333,185,13765,"0,0134398838",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,56","16,04"
"low bq, low freq, many artifacts, many samples",UPN2_072,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),12098,180,12467,"0,0144381166",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,54","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_073,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16541,237,17096,"0,0138628919",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,5","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_074,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),13595,181,14001,"0,012927648",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,47","15,48"
"low bq, low freq, many artifacts, many samples",UPN2_075,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),21596,319,22301,"0,0143042913",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,54","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_076,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),17784,292,18366,"0,0158989437",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,6","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_077,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),21445,337,22178,"0,0151952385",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,52","15,39"
"low bq, low freq, many artifacts, many samples",UPN2_078,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16744,288,17306,"0,0166416272",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,47","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_079,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),12455,195,12879,"0,0151409271",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,57","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_080,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16796,263,17377,"0,0151349485",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,59","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_081,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),21340,317,22095,"0,0143471374",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,62","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_082,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),24006,352,24775,"0,0142078708",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,57","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_083,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),23381,352,24141,"0,0145810033",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,6","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_084,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),18057,255,18628,"0,0136890702",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,55","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_085,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),17156,220,17714,"0,0124195552",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,47","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_086,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),12939,203,13415,"0,0151323146",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,46","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_087,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),26460,353,27323,"0,0129195184",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,59","15,13"
"low bq, low freq, many artifacts",UPN2_088,20,31024518,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser1335Arg/c.4003A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),19703,304,20387,"0,0149114632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,2,Damaging,"29,64","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_001,20,31024518,A,T,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser1335Cys/c.4003A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),7710,137,7918,"0,0173023491",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,1,Damaging,"30,19","17,19"
"low bq, low freq, many artifacts, many samples",UPN2_002,20,31024518,A,T,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser1335Cys/c.4003A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10331,152,10614,"0,0143207085",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,1,Damaging,"30,12","16,35"
"low bq, low freq, many artifacts, many samples",UPN2_041,20,31024518,A,T,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser1335Cys/c.4003A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15356,339,15922,"0,0212912951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,1,Damaging,"30,41","16,6"
"low bq, low freq, many artifacts, many samples",UPN2_004,20,31024518,A,T,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser1335Cys/c.4003A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1238,28,1277,"0,02192639",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,1,Damaging,"30,03","16,61"
"low bq, low freq, many artifacts, many samples",UPN2_005,20,31024518,A,T,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser1335Cys/c.4003A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3187,42,3261,"0,0128794848",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,1,Damaging,"30,27","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_048,20,31024518,A,T,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser1335Cys/c.4003A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),25007,536,25836,"0,0207462455",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,1,Damaging,"30,32","16,66"
"low bq, low freq, many artifacts, many samples",UPN2_006,20,31024518,A,T,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser1335Cys/c.4003A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3984,49,4076,"0,0120215898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,1,Damaging,"30,03","14,41"
"low bq, many samples",UPN2_051,20,31024518,A,T,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser1335Cys/c.4003A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17652,406,18285,"0,0222039923",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,1,Damaging,"30,35","16,57"
"low bq, low freq, many artifacts, many samples",UPN2_053,20,31024518,A,T,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser1335Cys/c.4003A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),22844,516,23649,"0,0218191044",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,1,Damaging,"30,16","16,54"
"low bq, low freq, many artifacts, many samples",UPN2_007,20,31024518,A,T,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser1335Cys/c.4003A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21875,361,22423,"0,0160995407",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,1,Damaging,"30,19","16,43"
"low bq, low freq, many artifacts, many samples",UPN2_008,20,31024518,A,T,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser1335Cys/c.4003A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),32369,501,33244,"0,0150703886",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,1,Damaging,"30,14","15,52"
"low bq, low freq, many artifacts, many samples",UPN2_009,20,31024518,A,T,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser1335Cys/c.4003A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),25922,424,26612,"0,015932662",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,1,Damaging,"30,18","16,34"
"low bq, low freq, many artifacts, many samples",UPN2_010,20,31024518,A,T,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser1335Cys/c.4003A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18429,283,18923,"0,0149553453",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,1,Damaging,"30,12","15,6"
"low bq, low freq, many artifacts, many samples",UPN2_011,20,31024518,A,T,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser1335Cys/c.4003A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),20881,329,21428,"0,0153537428",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,1,Damaging,"30,22","15,87"
"low bq, low freq, many artifacts, many samples",UPN2_012,20,31024518,A,T,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser1335Cys/c.4003A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),10636,190,10908,"0,0174184085",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,1,Damaging,"30,19","15,58"
"low bq, low freq, many artifacts",UPN2_013,20,31024518,A,T,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser1335Cys/c.4003A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),6630,108,6804,"0,0158730159",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,74",Deleterious,1,Damaging,"30,15","17,44"
"low freq, many artifacts",UPN2_044,20,31024520,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser1335Arg/c.4005T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),3259,50,3326,"0,0150330728",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,"0,002",Damaging,"32,18","30,28"
"low freq, many artifacts",UPN2_006,20,31024532,AC,A,frameshift_variant(HIGH||cca/|p.Pro1340fs/c.4019delC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A|INFO_REALIGN_3_PRIME),4027,59,4093,"0,0144148546",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,57",NA
"low bq, low freq, many artifacts",UPN2_057,20,31024542,A,T,missense_variant(MODERATE|MISSENSE|Aac/Tac|p.Asn1343Tyr/c.4027A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16963,184,17225,"0,010682148",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,1",Deleterious,2,Damaging,"32,19","21,98"
"low bq, low freq, many artifacts, many samples",UPN2_041,20,31024548,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met1345Leu/c.4033A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),15797,210,16064,"0,0130727092",0,0,0,0,1,0,0,0,1,"0,0233",NO,NO,NO,O,NO,rs377173817,NO,NA,NO,NO,"-0,36",Neutral,236,Tolerated,"32,96","23,21"
"low bq, low freq, many artifacts, many samples",UPN2_056,20,31024548,A,T,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met1345Leu/c.4033A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5278,75,5391,"0,0139120757",0,0,0,0,1,0,0,0,1,"0,0233",NO,NO,NO,O,NO,rs377173817,NO,NA,NO,NO,"-0,36",Neutral,236,Tolerated,"32,92","24,53"
"low bq, low freq, many artifacts, many samples",UPN2_059,20,31024566,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1351Pro/c.4051A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),23757,264,24100,"0,0109543568",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,3,Damaging,"31,54","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_060,20,31024566,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1351Pro/c.4051A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),20280,245,20618,"0,0118828208",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,3,Damaging,"31,57","15,86"
"low bq, low freq, many artifacts, many samples",UPN2_061,20,31024566,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1351Pro/c.4051A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),17662,187,17948,"0,0104189882",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,3,Damaging,"31,43","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_062,20,31024566,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1351Pro/c.4051A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),14693,175,14942,"0,0117119529",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,3,Damaging,"31,33","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_063,20,31024566,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1351Pro/c.4051A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),17264,207,17551,"0,0117941998",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,3,Damaging,"31,53",15
"low bq, low freq, many artifacts, many samples",UPN2_064,20,31024566,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1351Pro/c.4051A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),17058,200,17330,"0,0115406809",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,3,Damaging,"31,48","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_067,20,31024566,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1351Pro/c.4051A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),20712,211,21033,"0,0100318547",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,3,Damaging,"31,64","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_068,20,31024566,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1351Pro/c.4051A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),17867,193,18127,"0,010647101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,3,Damaging,"31,4","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_069,20,31024566,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1351Pro/c.4051A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),23830,256,24177,"0,0105885759",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,3,Damaging,"31,41","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_070,20,31024566,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1351Pro/c.4051A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),13870,162,14096,"0,011492622",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,3,Damaging,"31,36","15,48"
"low bq, low freq, many artifacts, many samples",UPN2_072,20,31024566,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1351Pro/c.4051A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),12412,149,12610,"0,011816019",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,3,Damaging,"31,38","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_073,20,31024566,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1351Pro/c.4051A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),17017,179,17293,"0,0103510091",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,3,Damaging,"31,52","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_075,20,31024566,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1351Pro/c.4051A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),22232,230,22593,"0,0101801443",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,3,Damaging,"31,57","15,37"
"low bq, low freq, many artifacts, many samples",UPN2_076,20,31024566,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1351Pro/c.4051A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),18260,217,18569,"0,0116861436",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,3,Damaging,"31,44","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_077,20,31024566,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1351Pro/c.4051A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),22095,234,22434,"0,0104305964",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,3,Damaging,"31,42","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_078,20,31024566,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1351Pro/c.4051A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),17180,224,17491,"0,0128065862",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,3,Damaging,"31,39","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_080,20,31024566,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1351Pro/c.4051A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),17312,184,17586,"0,0104628682",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,3,Damaging,"31,47","15,3"
"low bq, low freq, many artifacts, many samples",UPN2_081,20,31024566,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1351Pro/c.4051A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),21975,254,22314,"0,0113829883",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,3,Damaging,"31,53","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_082,20,31024566,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1351Pro/c.4051A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),24611,286,25005,"0,0114377125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,3,Damaging,"31,48","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_083,20,31024566,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1351Pro/c.4051A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),24038,274,24403,"0,0112281277",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,3,Damaging,"31,47",15
"low bq, low freq, many artifacts, many samples",UPN2_085,20,31024566,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1351Pro/c.4051A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),17604,209,17888,"0,0116838104",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,3,Damaging,"31,55","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_086,20,31024566,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1351Pro/c.4051A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),13329,158,13549,"0,0116613772",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,3,Damaging,"31,19","14,85"
"low bq, low freq, many artifacts",UPN2_087,20,31024566,A,C,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr1351Pro/c.4051A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),27068,330,27591,"0,0119604219",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,85",Neutral,3,Damaging,"31,52","15,27"
"low bq, low freq, many artifacts",UPN2_044,20,31024577,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu1354Asp/c.4062A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),3283,47,3344,"0,0140550239",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,"0,01",Damaging,"34,18","27,4"
"low bq, low freq, many artifacts, many samples",UPN2_059,20,31024579,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1355Ala/c.4064A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),23553,389,24087,"0,0161497903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,71",Neutral,3,Damaging,"31,39","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_060,20,31024579,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1355Ala/c.4064A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),20199,317,20612,"0,0153793906",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,71",Neutral,3,Damaging,"31,44","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_061,20,31024579,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1355Ala/c.4064A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),17592,268,17949,"0,0149311939",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,71",Neutral,3,Damaging,"31,38","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_062,20,31024579,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1355Ala/c.4064A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),14630,221,14933,"0,0147994375",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,71",Neutral,3,Damaging,"31,19","15,46"
"low bq, low freq, many artifacts, many samples",UPN2_063,20,31024579,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1355Ala/c.4064A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),17196,268,17552,"0,0152689152",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,71",Neutral,3,Damaging,"31,33","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_064,20,31024579,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1355Ala/c.4064A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16981,265,17317,"0,0153028816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,71",Neutral,3,Damaging,"31,35","15,48"
"low bq, low freq, many artifacts, many samples",UPN2_065,20,31024579,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1355Ala/c.4064A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),18736,265,19072,"0,0138947148",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,71",Neutral,3,Damaging,"31,51","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_066,20,31024579,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1355Ala/c.4064A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),22233,310,22658,"0,0136817018",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,71",Neutral,3,Damaging,"31,37","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_067,20,31024579,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1355Ala/c.4064A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),20633,289,21021,"0,0137481566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,71",Neutral,3,Damaging,"31,53","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_068,20,31024579,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1355Ala/c.4064A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),17760,281,18120,"0,0155077263",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,71",Neutral,3,Damaging,"31,4","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_069,20,31024579,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1355Ala/c.4064A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),23684,370,24173,"0,0153063335",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,71",Neutral,3,Damaging,"31,34","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_070,20,31024579,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1355Ala/c.4064A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),13818,224,14096,"0,0158910329",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,71",Neutral,3,Damaging,"31,24","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_071,20,31024579,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1355Ala/c.4064A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),13647,209,13903,"0,0150327267",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,71",Neutral,3,Damaging,"31,42","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_072,20,31024579,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1355Ala/c.4064A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),12329,194,12602,"0,0153943818",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,71",Neutral,3,Damaging,"31,3","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_073,20,31024579,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1355Ala/c.4064A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16919,234,17284,"0,0135385327",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,71",Neutral,3,Damaging,"31,46","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_074,20,31024579,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1355Ala/c.4064A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),13850,196,14122,"0,013879054",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,71",Neutral,3,Damaging,"31,48","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_075,20,31024579,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1355Ala/c.4064A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),22177,287,22583,"0,0127086747",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,71",Neutral,3,Damaging,"31,38","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_076,20,31024579,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1355Ala/c.4064A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),18132,283,18554,"0,0152527757",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,71",Neutral,3,Damaging,"31,31","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_077,20,31024579,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1355Ala/c.4064A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),21961,328,22433,"0,0146213168",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,71",Neutral,3,Damaging,"31,42","15,4"
"low bq, low freq, many artifacts, many samples",UPN2_078,20,31024579,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1355Ala/c.4064A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),17122,276,17484,"0,0157858614",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,71",Neutral,3,Damaging,"31,44","15,62"
"low bq, low freq, many artifacts, many samples",UPN2_079,20,31024579,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1355Ala/c.4064A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),12738,185,12998,"0,0142329589",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,71",Neutral,3,Damaging,"31,46","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_080,20,31024579,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1355Ala/c.4064A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),17197,290,17581,"0,0164950799",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,71",Neutral,3,Damaging,"31,34","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_081,20,31024579,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1355Ala/c.4064A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),21832,322,22306,"0,0144355779",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,71",Neutral,3,Damaging,"31,44","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_082,20,31024579,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1355Ala/c.4064A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),24496,380,24998,"0,0152012161",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,71",Neutral,3,Damaging,"31,32","15,46"
"low bq, low freq, many artifacts, many samples",UPN2_083,20,31024579,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1355Ala/c.4064A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),23952,326,24398,"0,013361751",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,71",Neutral,3,Damaging,"31,27","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_084,20,31024579,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1355Ala/c.4064A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),18375,332,18801,"0,0176586352",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,71",Neutral,3,Damaging,"31,3","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_085,20,31024579,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1355Ala/c.4064A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),17481,304,17882,"0,0170003355",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,71",Neutral,3,Damaging,"31,37","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_086,20,31024579,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1355Ala/c.4064A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),13235,231,13547,"0,0170517458",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,71",Neutral,3,Damaging,"31,18","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_087,20,31024579,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1355Ala/c.4064A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),27037,414,27580,"0,0150108774",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,71",Neutral,3,Damaging,"31,36","15,14"
"low bq, low freq, many artifacts",UPN2_088,20,31024579,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp1355Ala/c.4064A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),20240,297,20633,"0,0143944167",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,71",Neutral,3,Damaging,"31,57","15,69"
"low freq, many artifacts",UPN2_041,20,31024606,T,C,missense_variant(MODERATE|MISSENSE|gTt/gCt|p.Val1364Ala/c.4091T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),7725,88,7836,"0,0112302195",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,31",Neutral,"0,42",Tolerated,"34,29","33,44"
"low freq, many artifacts",UPN2_044,20,31024614,G,T,missense_variant(MODERATE|MISSENSE|Gtc/Ttc|p.Val1367Phe/c.4099G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1622,39,1664,"0,0234375",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,65",Deleterious,"0,001",Damaging,"35,3","34,31"
"low freq, many artifacts, many samples",UPN2_001,20,31024615,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1367Gly/c.4100T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),7645,83,7786,"0,0106601593",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"32,01","30,65"
"low freq, many artifacts, many samples",UPN2_014,20,31024615,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1367Gly/c.4100T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),14593,188,14906,"0,0126123709",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"31,93","30,49"
"low freq, many artifacts, many samples",UPN2_016,20,31024615,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1367Gly/c.4100T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9457,98,9616,"0,0101913478",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"31,96","30,35"
"low bq, low freq, many samples",UPN2_017,20,31024615,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1367Gly/c.4100T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),6937,77,7072,"0,010888009",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"32,03","29,57"
"low freq, many artifacts, many samples",UPN2_019,20,31024615,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1367Gly/c.4100T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),10834,112,11025,"0,0101587302",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"31,96","30,36"
"low bq, low freq, many samples",UPN2_020,20,31024615,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1367Gly/c.4100T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9331,114,9530,"0,0119622246",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"31,97","30,89"
"low freq, many artifacts, many samples",UPN2_021,20,31024615,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1367Gly/c.4100T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),11022,131,11243,"0,0116516944",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"32,06","30,32"
"low bq, low freq, many samples",UPN2_002,20,31024615,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1367Gly/c.4100T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),10141,129,10336,"0,0124806502",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"32,05","30,29"
"low bq, low freq, many samples",UPN2_003,20,31024615,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1367Gly/c.4100T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),2073,24,2115,"0,0113475177",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"31,91","29,17"
"low freq, many artifacts, many samples",UPN2_004,20,31024615,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1367Gly/c.4100T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),1690,24,1733,"0,0138488171",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"31,83","30,79"
"low bq, low freq, many samples",UPN2_027,20,31024615,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1367Gly/c.4100T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),17905,195,18231,"0,0106960671",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"31,96","29,95"
"low bq, low freq, many samples",UPN2_029,20,31024615,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1367Gly/c.4100T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),15091,191,15408,"0,0123961578",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"31,94","30,8"
"low freq, many artifacts, many samples",UPN2_005,20,31024615,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1367Gly/c.4100T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3209,57,3286,"0,0173463177",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"31,93","30,26"
"low freq, many artifacts, many samples",UPN2_035,20,31024615,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1367Gly/c.4100T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),13066,159,13323,"0,011934249",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"31,94","29,91"
"low bq, low freq, many samples",UPN2_036,20,31024615,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1367Gly/c.4100T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),13226,149,13486,"0,0110484947",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"31,96","30,23"
"low bq, low freq, many samples",UPN2_006,20,31024615,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1367Gly/c.4100T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),4030,54,4107,"0,0131482834",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"32,21","28,87"
"low bq, low freq, many samples",UPN2_038,20,31024615,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1367Gly/c.4100T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),28181,293,28681,"0,0102158223",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"31,95","30,47"
"low freq, many artifacts, many samples",UPN2_039,20,31024615,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1367Gly/c.4100T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),13384,155,13632,"0,0113703052",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"31,92","30,46"
"low bq, low freq, many samples",UPN2_008,20,31024615,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1367Gly/c.4100T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),32906,352,33483,"0,0105127975",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"31,98","29,41"
"low bq, low freq, many artifacts, many samples",UPN2_060,20,31024615,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1367Gly/c.4100T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),14666,154,14894,"0,0103397341",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"30,19","26,34"
"low bq, low freq, many samples",UPN2_061,20,31024615,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1367Gly/c.4100T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),13323,153,13548,"0,0112931798",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"30,34","26,53"
"low bq, low freq, many samples",UPN2_062,20,31024615,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1367Gly/c.4100T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),11626,147,11841,"0,012414492",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"30,27","26,44"
"low bq, low freq, many samples",UPN2_063,20,31024615,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1367Gly/c.4100T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),13037,182,13291,"0,0136934768",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"30,38","28,02"
"low bq, low freq, many samples",UPN2_064,20,31024615,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1367Gly/c.4100T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),12047,160,12271,"0,0130388721",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"30,28","25,88"
"low bq, low freq, many samples",UPN2_068,20,31024615,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1367Gly/c.4100T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),13562,157,13817,"0,0113628139",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"30,31","26,34"
"low bq, low freq, many artifacts, many samples",UPN2_069,20,31024615,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1367Gly/c.4100T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),16552,169,16825,"0,0100445765",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"30,23","25,59"
"low bq, low freq, many artifacts, many samples",UPN2_070,20,31024615,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1367Gly/c.4100T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),10200,107,10358,"0,0103301796",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"30,22","25,31"
"low bq, low freq, many samples",UPN2_071,20,31024615,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1367Gly/c.4100T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),10325,130,10503,"0,012377416",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"30,35","27,31"
"low bq, low freq, many samples",UPN2_072,20,31024615,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1367Gly/c.4100T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9716,153,9916,"0,0154296087",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"30,36",29
"low bq, low freq, many artifacts, many samples",UPN2_073,20,31024615,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1367Gly/c.4100T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),12156,130,12343,"0,0105322855",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"30,19","25,48"
"low bq, low freq, many artifacts, many samples",UPN2_074,20,31024615,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1367Gly/c.4100T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),10274,109,10445,"0,0104356151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"30,32","26,73"
"low bq, low freq, many artifacts, many samples",UPN2_075,20,31024615,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1367Gly/c.4100T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),16043,176,16306,"0,0107935729",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"30,34","26,84"
"low bq, low freq, many samples",UPN2_077,20,31024615,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1367Gly/c.4100T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),16584,187,16858,"0,0110926563",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"30,36","25,3"
"low bq, low freq, many samples",UPN2_078,20,31024615,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1367Gly/c.4100T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),13179,159,13427,"0,0118418113",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"30,31","26,41"
"low bq, low freq, many samples",UPN2_080,20,31024615,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1367Gly/c.4100T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),13835,201,14120,"0,0142351275",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"30,4","28,06"
"low bq, low freq, many samples",UPN2_083,20,31024615,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1367Gly/c.4100T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),17130,183,17435,"0,0104961285",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"30,26","26,73"
"low bq, low freq, many artifacts, many samples",UPN2_084,20,31024615,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1367Gly/c.4100T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),14872,160,15124,"0,0105792118",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"30,33","26,11"
"low bq, low freq, many artifacts",UPN2_086,20,31024615,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1367Gly/c.4100T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9770,103,9945,"0,0103569633",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,0,Damaging,"30,34","25,07"
"low freq, many artifacts",UPN2_044,20,31024626,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys1371Glu/c.4111A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3132,52,3198,"0,0162601626",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,14",Neutral,"0,006",Damaging,"34,91","35,75"
"low freq, many artifacts",UPN2_044,20,31024633,T,C,missense_variant(MODERATE|MISSENSE|tTt/tCt|p.Phe1373Ser/c.4118T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3144,46,3201,"0,0143705092",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-0,15",Neutral,"0,099",Tolerated,"35,12","35,07"
"many artifacts, ins and del, many samples",UPN2_001,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),7788,549,7807,"0,0703215063",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,29",NA
"many artifacts, ins and del, many samples",UPN2_014,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),14882,1234,14931,"0,0826468421",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,32",NA
"many artifacts, ins and del, many samples",UPN2_015,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),20319,1315,20395,"0,0644765874",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,36",NA
"many artifacts, ins and del, many samples",UPN2_016,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),9607,848,9638,"0,0879850591",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,37",NA
"many artifacts, ins and del, many samples",UPN2_017,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),7064,537,7093,"0,0757084449",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,4",NA
"many artifacts, ins and del, many samples",UPN2_018,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),10683,850,10712,"0,0793502614",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,4",NA
"many artifacts, ins and del, many samples",UPN2_019,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),11024,860,11048,"0,0778421434",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,37",NA
"many artifacts, ins and del, many samples",UPN2_020,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),9515,635,9551,"0,0664851848",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,3",NA
"many artifacts, ins and del, many samples",UPN2_021,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),11236,762,11268,"0,0676251331",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,39",NA
"many artifacts, ins and del, many samples",UPN2_002,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),10335,587,10363,"0,056643829",0,0,0,1,0,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,26",NA
"many artifacts, ins and del, many samples",UPN2_003,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),2109,145,2118,"0,0684608121",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,34",NA
"many artifacts, ins and del, many samples",UPN2_022,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),14843,993,14885,"0,0667114545",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,36",NA
"many artifacts, ins and del, many samples",UPN2_023,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),14861,1002,14922,"0,0671491757",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,38",NA
"many artifacts, ins and del, many samples",UPN2_024,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),7623,539,7644,"0,0705128205",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,24",NA
"many artifacts, ins and del, many samples",UPN2_025,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),18368,1388,18414,"0,0753774302",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,39",NA
"many artifacts, ins and del, many samples",UPN2_026,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),17740,1438,17798,"0,080795595",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,4",NA
"many artifacts, ins and del, many samples",UPN2_004,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),1738,292,1739,"0,1679125934",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,14",NA
"many artifacts, ins and del, many samples",UPN2_027,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),18221,1353,18282,"0,0740072202",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,4",NA
"many artifacts, ins and del, many samples",UPN2_089,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),11560,992,11588,"0,0856057991",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,36",NA
"many artifacts, ins and del, many samples",UPN2_028,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),13252,1171,13288,"0,0881246237",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,33",NA
"many artifacts, ins and del, many samples",UPN2_044,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),3190,192,3201,"0,0599812559",0,0,0,1,0,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,96",NA
"many artifacts, ins and del, many samples",UPN2_029,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),15411,1152,15465,"0,0744907856",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,38",NA
"many artifacts, ins and del, many samples",UPN2_030,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),15640,1052,15684,"0,0670747258",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,38",NA
"many artifacts, ins and del, many samples",UPN2_031,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),10929,654,10958,"0,0596824238",0,0,0,1,0,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,4",NA
"many artifacts, ins and del, many samples",UPN2_005,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),3282,229,3290,"0,0696048632",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,24",NA
"many artifacts, ins and del, many samples",UPN2_045,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),22267,1248,22343,"0,0558564204",0,0,0,1,0,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,04",NA
"many artifacts, ins and del, many samples",UPN2_032,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),5514,446,5523,"0,0807532138",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,42",NA
many samples,UPN2_046,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),21389,1038,21495,"0,0482903001",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,09",NA
"many artifacts, ins and del, many samples",UPN2_033,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),13067,1122,13111,"0,0855769964",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,33",NA
"many artifacts, ins and del, many samples",UPN2_034,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),4527,367,4546,"0,0807303124",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,32",NA
"many artifacts, ins and del, many samples",UPN2_035,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),13300,786,13344,"0,0589028777",0,0,0,1,0,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,33",NA
"many artifacts, ins and del, many samples",UPN2_036,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),13505,738,13530,"0,0545454545",0,0,0,1,0,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,4",NA
many samples,UPN2_050,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),19808,883,19877,"0,0444232027",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,05",NA
"many artifacts, ins and del, many samples",UPN2_037,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),26161,1935,26262,"0,0736806032",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,36",NA
"many artifacts, ins and del, many samples",UPN2_051,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),17785,1026,17870,"0,0574146614",0,0,0,1,0,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,04",NA
"many artifacts, ins and del, many samples",UPN2_052,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),17868,1380,17957,"0,0768502534",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,98",NA
"many artifacts, ins and del, many samples",UPN2_038,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),28652,2168,28751,"0,0754060728",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,39",NA
"many artifacts, ins and del, many samples",UPN2_039,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),13675,936,13721,"0,0682166023",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,43",NA
"many artifacts, ins and del, many samples",UPN2_053,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),23316,1246,23406,"0,0532342134",0,0,0,1,0,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,08",NA
"many artifacts, ins and del, many samples",UPN2_054,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),15811,997,15888,"0,0627517623",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,05",NA
"many artifacts, ins and del, many samples",UPN2_007,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),22275,1279,22332,"0,0572720759",0,0,0,1,0,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,23",NA
"many artifacts, ins and del, many samples",UPN2_008,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),33464,2586,33565,"0,0770445404",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,26",NA
"many artifacts, ins and del, many samples",UPN2_009,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),25933,1896,25991,"0,0729483283",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,24",NA
"many artifacts, ins and del, many samples",UPN2_010,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),17800,1077,17870,"0,0602686066",0,0,0,1,0,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,27",NA
many samples,UPN2_011,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),20134,903,20178,"0,0447517098",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,26",NA
"many artifacts, ins and del, many samples",UPN2_090,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),10900,793,10923,"0,0725991028",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,34",NA
"many artifacts, ins and del, many samples",UPN2_057,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),19016,1167,19077,"0,0611731404",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,01",NA
"many artifacts, ins and del, many samples",UPN2_012,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),10546,545,10581,"0,051507419",0,0,0,1,0,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,31",NA
"inspected, many artifacts, ins and del, many samples",UPN2_040,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),10168,514,10201,"0,0503872169",0,0,0,1,0,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,35",NA
many samples,UPN2_013,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),6592,330,6621,"0,0498414137",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,23",NA
many samples,UPN2_091,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),7856,351,7885,"0,0445149017",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,33",NA
"many artifacts, ins and del, many samples",UPN2_092,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),6588,483,6620,"0,0729607251",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,34",NA
"many artifacts, ins and del, many samples",UPN2_093,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),6395,476,6410,"0,0742589704",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,43",NA
"many artifacts, ins and del, many samples",UPN2_061,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),13507,830,13566,"0,0611823677",0,0,0,1,0,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,16",NA
"many artifacts, ins and del, many samples",UPN2_062,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),11821,765,11858,"0,0645134087",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,21",NA
many samples,UPN2_066,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),16495,755,16552,"0,0456138231",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,15",NA
"many artifacts, ins and del, many samples",UPN2_067,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),16153,841,16207,"0,0518911581",0,0,0,1,0,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,11",NA
"many artifacts, ins and del, many samples",UPN2_068,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),13781,935,13834,"0,0675871042",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,14",NA
"many artifacts, ins and del, many samples",UPN2_069,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),16796,928,16866,"0,0550219376",0,0,0,1,0,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,18",NA
many samples,UPN2_070,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),10342,507,10378,"0,0488533436",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,18",NA
many samples,UPN2_075,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),16289,786,16351,"0,0480704544",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,18",NA
"many artifacts, ins and del, many samples",UPN2_076,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),13398,849,13446,"0,0631414547",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,17",NA
"many artifacts, ins and del, many samples",UPN2_077,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),16809,987,16880,"0,058471564",0,0,0,1,0,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,15",NA
many samples,UPN2_078,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),13431,571,13465,"0,0424062384",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,17",NA
many samples,UPN2_079,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),9250,393,9281,"0,0423445749",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,16",NA
"many artifacts, ins and del, many samples",UPN2_083,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),17418,884,17478,"0,0505778693",0,0,0,1,0,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,22",NA
"many artifacts, ins and del, many samples",UPN2_084,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),15101,811,15163,"0,053485458",0,0,0,1,0,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,17",NA
many samples,UPN2_086,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),9954,427,9974,"0,0428113094",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,2",NA
many samples,UPN2_088,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),14926,681,14976,"0,0454727564",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,15",NA
"many artifacts, ins and del, many samples",UPN2_094,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),13720,914,13751,"0,0664678932",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,42",NA
"many artifacts, ins and del, many samples",UPN2_095,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),11422,877,11449,"0,0766005765",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,35",NA
"many artifacts, ins and del, many samples",UPN2_096,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),13329,990,13371,"0,0740408346",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,4",NA
"many artifacts, ins and del, many samples",UPN2_097,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),15215,1094,15255,"0,0717141921",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,37",NA
"many artifacts, ins and del, many samples",UPN2_099,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),6718,473,6735,"0,0702301411",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,41",NA
"many artifacts, ins and del, many samples",UPN2_100,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),11056,837,11084,"0,0755142548",0,0,0,1,0,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,41",NA
"many artifacts, ins and del, many samples",UPN2_101,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),11403,827,11429,"0,0723597865",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,36",NA
"many artifacts, ins and del, many samples",UPN2_102,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),11879,959,11904,"0,0805611559",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,37",NA
"many artifacts, ins and del, many samples",UPN2_103,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),11428,867,11461,"0,0756478492",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,37",NA
"many artifacts, ins and del, many samples",UPN2_104,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),14526,1002,14565,"0,0687950566",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,39",NA
"many artifacts, ins and del, many samples",UPN2_105,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),12977,826,13003,"0,0635238022",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,39",NA
"many artifacts, ins and del, many samples",UPN2_107,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),20051,1362,20125,"0,0676770186",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,4",NA
"many artifacts, ins and del, many samples",UPN2_108,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),17083,1019,17138,"0,0594585132",0,0,0,1,0,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,37",NA
"many artifacts, ins and del, many samples",UPN2_109,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),16556,1236,16607,"0,0744264467",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,42",NA
"many artifacts, ins and del, many samples",UPN2_110,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),18257,1341,18298,"0,073286698",0,1,0,1,0,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,4",NA
"inspected, ins and del, many samples",UPN2_111,20,31024635,G,GT,frameshift_variant(HIGH||gtg/gtTg|p.Pro1377fs/c.4121dupT|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|GT|INFO_REALIGN_3_PRIME),14177,1056,14205,"0,0743400211",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,39",NA
"many artifacts, ins and del, many samples",UPN2_036,20,31024636,T,TG,frameshift_variant(HIGH||ggt/ggGt|p.Pro1377fs/c.4127dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|TG|INFO_REALIGN_3_PRIME),13425,151,13531,"0,0111595595",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,12",NA
"many artifacts, ins and del, many samples",UPN2_039,20,31024636,T,TG,frameshift_variant(HIGH||ggt/ggGt|p.Pro1377fs/c.4127dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|TG|INFO_REALIGN_3_PRIME),13579,201,13721,"0,0146490781",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,15",NA
"many artifacts, ins and del, many samples",UPN2_040,20,31024636,T,TG,frameshift_variant(HIGH||ggt/ggGt|p.Pro1377fs/c.4127dupG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|TG|INFO_REALIGN_3_PRIME),10116,125,10201,"0,0122537006",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,19",NA
"many artifacts, ins and del, many samples",UPN2_014,20,31024636,TG,T,frameshift_variant(HIGH||ggt/|p.Gly1376fs/c.4127delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T|INFO_REALIGN_3_PRIME),14311,154,14932,"0,0103134208",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,27",NA
"low freq, many artifacts, many samples",UPN2_041,20,31024636,TG,T,frameshift_variant(HIGH||ggt/|p.Gly1376fs/c.4127delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T|INFO_REALIGN_3_PRIME),8200,133,8347,"0,0159338685",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,21",NA
"many artifacts, ins and del, many samples",UPN2_042,20,31024636,TG,T,frameshift_variant(HIGH||ggt/|p.Gly1376fs/c.4127delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T|INFO_REALIGN_3_PRIME),23965,265,24387,"0,0108664452",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,03",NA
"many artifacts, ins and del, many samples",UPN2_043,20,31024636,TG,T,frameshift_variant(HIGH||ggt/|p.Gly1376fs/c.4127delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T|INFO_REALIGN_3_PRIME),15918,209,16400,"0,0127439024",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,04",NA
"many artifacts, ins and del, many samples",UPN2_005,20,31024636,TG,T,frameshift_variant(HIGH||ggt/|p.Gly1376fs/c.4127delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T|INFO_REALIGN_3_PRIME),3145,41,3291,"0,0124582194",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,24",NA
"many artifacts, ins and del, many samples",UPN2_046,20,31024636,TG,T,frameshift_variant(HIGH||ggt/|p.Gly1376fs/c.4127delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T|INFO_REALIGN_3_PRIME),20839,235,21498,"0,0109312494",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,95",NA
"many artifacts, ins and del, many samples",UPN2_034,20,31024636,TG,T,frameshift_variant(HIGH||ggt/|p.Gly1376fs/c.4127delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T|INFO_REALIGN_3_PRIME),4348,47,4548,"0,0103342128",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,37",NA
"many artifacts, ins and del, many samples",UPN2_047,20,31024636,TG,T,frameshift_variant(HIGH||ggt/|p.Gly1376fs/c.4127delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T|INFO_REALIGN_3_PRIME),27128,334,27551,"0,0121229719",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,04",NA
"many artifacts, ins and del, many samples",UPN2_006,20,31024636,TG,T,frameshift_variant(HIGH||ggt/|p.Gly1376fs/c.4127delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T|INFO_REALIGN_3_PRIME),4100,49,4164,"0,0117675312",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,19",NA
"many artifacts, ins and del, many samples",UPN2_049,20,31024636,TG,T,frameshift_variant(HIGH||ggt/|p.Gly1376fs/c.4127delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T|INFO_REALIGN_3_PRIME),12549,166,12830,"0,0129384256",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,92",NA
"many artifacts, ins and del, many samples",UPN2_050,20,31024636,TG,T,frameshift_variant(HIGH||ggt/|p.Gly1376fs/c.4127delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T|INFO_REALIGN_3_PRIME),19283,239,19877,"0,0120239473",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,97",NA
"many artifacts, ins and del, many samples",UPN2_052,20,31024636,TG,T,frameshift_variant(HIGH||ggt/|p.Gly1376fs/c.4127delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T|INFO_REALIGN_3_PRIME),17394,221,17962,"0,0123037524",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,92",NA
"many artifacts, ins and del, many samples",UPN2_055,20,31024636,TG,T,frameshift_variant(HIGH||ggt/|p.Gly1376fs/c.4127delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T|INFO_REALIGN_3_PRIME),25085,280,25698,"0,0108957896",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,01",NA
"many artifacts, ins and del, many samples",UPN2_057,20,31024636,TG,T,frameshift_variant(HIGH||ggt/|p.Gly1376fs/c.4127delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T|INFO_REALIGN_3_PRIME),18453,217,19082,"0,0113719736",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,95",NA
"many artifacts, ins and del, many samples",UPN2_093,20,31024636,TG,T,frameshift_variant(HIGH||ggt/|p.Gly1376fs/c.4127delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T|INFO_REALIGN_3_PRIME),6185,66,6412,"0,0102932002",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,29",NA
"low freq, many artifacts, many samples",UPN2_061,20,31024636,TG,T,frameshift_variant(HIGH||ggt/|p.Gly1376fs/c.4127delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T|INFO_REALIGN_3_PRIME),13328,136,13570,"0,0100221076",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,03",NA
"low freq, many artifacts, many samples",UPN2_076,20,31024636,TG,T,frameshift_variant(HIGH||ggt/|p.Gly1376fs/c.4127delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T|INFO_REALIGN_3_PRIME),13207,138,13452,"0,0102586976",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,02",NA
"many artifacts, ins and del, many samples",UPN2_083,20,31024636,TG,T,frameshift_variant(HIGH||ggt/|p.Gly1376fs/c.4127delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T|INFO_REALIGN_3_PRIME),17156,199,17481,"0,0113837881",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,09",NA
"many artifacts, ins and del, many samples",UPN2_094,20,31024636,TG,T,frameshift_variant(HIGH||ggt/|p.Gly1376fs/c.4127delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T|INFO_REALIGN_3_PRIME),13364,142,13750,"0,0103272727",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,35",NA
"many artifacts, ins and del, many samples",UPN2_095,20,31024636,TG,T,frameshift_variant(HIGH||ggt/|p.Gly1376fs/c.4127delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T|INFO_REALIGN_3_PRIME),11146,115,11454,"0,0100401606",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,3",NA
"many artifacts, ins and del, many samples",UPN2_096,20,31024636,TG,T,frameshift_variant(HIGH||ggt/|p.Gly1376fs/c.4127delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T|INFO_REALIGN_3_PRIME),13017,142,13375,"0,0106168224",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,33",NA
"low freq, many artifacts",UPN2_098,20,31024636,TG,T,frameshift_variant(HIGH||ggt/|p.Gly1376fs/c.4127delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T|INFO_REALIGN_3_PRIME),10877,111,11097,"0,0100027034",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,32",NA
"many artifacts, ins and del, many samples",UPN2_101,20,31024636,TG,T,frameshift_variant(HIGH||ggt/|p.Gly1376fs/c.4127delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T|INFO_REALIGN_3_PRIME),11113,121,11432,"0,0105843247",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,36",NA
"many artifacts, ins and del, many samples",UPN2_106,20,31024636,TG,T,frameshift_variant(HIGH||ggt/|p.Gly1376fs/c.4127delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T|INFO_REALIGN_3_PRIME),15593,172,15875,"0,0108346457",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,31",NA
"low freq, many artifacts",UPN2_006,20,31024644,C,T,missense_variant(MODERATE|MISSENSE|Cct/Tct|p.Pro1377Ser/c.4129C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4104,54,4165,"0,0129651861",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,"0,108",Tolerated,"35,31","32,7"
"low freq, many artifacts",UPN2_044,20,31024648,T,C,missense_variant(MODERATE|MISSENSE|cTt/cCt|p.Leu1378Pro/c.4133T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3125,60,3201,"0,0187441425",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,"0,126",Tolerated,"35,19","34,95"
"low freq, many artifacts",UPN2_044,20,31024653,G,C,missense_variant(MODERATE|MISSENSE|Gca/Cca|p.Ala1380Pro/c.4138G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3138,52,3201,"0,0162449235",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,37",Neutral,"0,007",Damaging,"34,7","34,42"
"low bq, low freq, many artifacts",UPN2_081,20,31024690,C,A,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro1392His/c.4175C>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),5296,60,5369,"0,0111752654",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,0,Damaging,"32,08","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_001,20,31024702,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val1396Glu/c.4187T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),3785,40,3833,"0,0104356901",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,6,Damaging,"34,38","18,08"
"low bq, low freq, many artifacts, many samples",UPN2_042,20,31024702,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val1396Glu/c.4187T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),10849,117,11016,"0,010620915",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,6,Damaging,"33,75","18,63"
"low bq, low freq, many artifacts, many samples",UPN2_043,20,31024702,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val1396Glu/c.4187T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),8163,83,8269,"0,0100374894",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,6,Damaging,"33,8","17,18"
"low bq, low freq, many artifacts, many samples",UPN2_044,20,31024702,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val1396Glu/c.4187T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),1505,22,1531,"0,014369693",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,6,Damaging,"33,62","15,59"
"low bq, low freq, many artifacts, many samples",UPN2_045,20,31024702,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val1396Glu/c.4187T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),11182,122,11341,"0,0107574288",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,6,Damaging,"33,78","18,5"
"low bq, low freq, many artifacts, many samples",UPN2_046,20,31024702,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val1396Glu/c.4187T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),10933,113,11082,"0,0101967154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,6,Damaging,"33,67","18,73"
"low bq, low freq, many artifacts, many samples",UPN2_048,20,31024702,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val1396Glu/c.4187T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),3867,49,3947,"0,012414492",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,6,Damaging,"33,77","17,82"
"low bq, low freq, many artifacts, many samples",UPN2_049,20,31024702,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val1396Glu/c.4187T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),6170,71,6260,"0,011341853",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,6,Damaging,"33,67","18,37"
"low bq, low freq, many artifacts, many samples",UPN2_050,20,31024702,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val1396Glu/c.4187T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),9935,102,10068,"0,0101311085",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,6,Damaging,"33,63","19,25"
"low bq, low freq, many artifacts, many samples",UPN2_051,20,31024702,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val1396Glu/c.4187T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),8499,94,8634,"0,0108871902",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,6,Damaging,"33,75","18,79"
"low bq, low freq, many artifacts, many samples",UPN2_053,20,31024702,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val1396Glu/c.4187T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),11318,136,11502,"0,0118240306",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,6,Damaging,"33,82","19,98"
"low bq, low freq, many artifacts, many samples",UPN2_057,20,31024702,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val1396Glu/c.4187T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),10290,112,10461,"0,0107064334",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,6,Damaging,"33,73","18,98"
"low bq, low freq, many artifacts",UPN2_058,20,31024702,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val1396Glu/c.4187T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),9003,96,9134,"0,0105101817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,73",Neutral,6,Damaging,"33,7","18,08"
"low freq, many artifacts",UPN2_056,20,31024705,G,A,missense_variant(MODERATE|MISSENSE|gGt/gAt|p.Gly1397Asp/c.4190G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),1706,26,1740,"0,0149425287",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,32",Neutral,"0,565",Tolerated,"33,78","34,31"
"low bq, low freq, many artifacts",UPN2_048,20,31024710,T,A,missense_variant(MODERATE|MISSENSE|Ttg/Atg|p.Leu1399Met/c.4195T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),3895,40,3945,"0,010139417",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,7,Damaging,"34,05","19,17"
"low bq, low freq, many artifacts, many samples",UPN2_042,20,31024711,T,A,stop_gained(HIGH|NONSENSE|tTg/tAg|p.Leu1399*/c.4196T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),10840,129,11008,"0,01171875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,56","17,01"
"low bq, low freq, many artifacts, many samples",UPN2_043,20,31024711,T,A,stop_gained(HIGH|NONSENSE|tTg/tAg|p.Leu1399*/c.4196T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),8135,98,8264,"0,0118586641",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,68","18,4"
"low bq, low freq, many artifacts, many samples",UPN2_045,20,31024711,T,A,stop_gained(HIGH|NONSENSE|tTg/tAg|p.Leu1399*/c.4196T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),11168,121,11330,"0,0106796117",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,64","18,29"
"low bq, low freq, many artifacts, many samples",UPN2_046,20,31024711,T,A,stop_gained(HIGH|NONSENSE|tTg/tAg|p.Leu1399*/c.4196T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),10915,131,11080,"0,0118231047",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,6","17,69"
"low bq, low freq, many artifacts, many samples",UPN2_048,20,31024711,T,A,stop_gained(HIGH|NONSENSE|tTg/tAg|p.Leu1399*/c.4196T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),3879,44,3945,"0,0111533587",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,55","18,3"
"low bq, low freq, many artifacts, many samples",UPN2_049,20,31024711,T,A,stop_gained(HIGH|NONSENSE|tTg/tAg|p.Leu1399*/c.4196T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),6160,72,6257,"0,011507112",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,66","17,11"
"low bq, low freq, many artifacts, many samples",UPN2_050,20,31024711,T,A,stop_gained(HIGH|NONSENSE|tTg/tAg|p.Leu1399*/c.4196T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),9877,132,10062,"0,0131186643",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,62","19,38"
"low bq, low freq, many artifacts, many samples",UPN2_054,20,31024711,T,A,stop_gained(HIGH|NONSENSE|tTg/tAg|p.Leu1399*/c.4196T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),8021,93,8145,"0,0114180479",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,69","16,82"
"low bq, low freq, many artifacts, many samples",UPN2_055,20,31024711,T,A,stop_gained(HIGH|NONSENSE|tTg/tAg|p.Leu1399*/c.4196T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),12077,137,12270,"0,0111654442",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,58","18,18"
"low bq, low freq, many artifacts, many samples",UPN2_056,20,31024711,T,A,stop_gained(HIGH|NONSENSE|tTg/tAg|p.Leu1399*/c.4196T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),1708,27,1738,"0,0155350978",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,75","15,48"
"low bq, low freq, many artifacts, many samples",UPN2_057,20,31024711,T,A,stop_gained(HIGH|NONSENSE|tTg/tAg|p.Leu1399*/c.4196T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),10293,114,10453,"0,01090596",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,56","16,93"
"low bq, low freq, many artifacts",UPN2_058,20,31024711,T,A,stop_gained(HIGH|NONSENSE|tTg/tAg|p.Leu1399*/c.4196T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),8984,99,9125,"0,0108493151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,61","18,43"
"low freq, many artifacts",UPN2_048,20,31024717,G,A,missense_variant(MODERATE|MISSENSE|gGg/gAg|p.Gly1401Glu/c.4202G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),3992,43,4059,"0,0105937423",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,6",Deleterious,"0,002",Damaging,"33,25","33,4"
"low bq, low freq, many artifacts, many samples",UPN2_059,20,31024720,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met1402Arg/c.4205T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9509,167,9731,"0,0171616483",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,96",Neutral,1,Damaging,"29,25","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_060,20,31024720,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met1402Arg/c.4205T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9240,150,9453,"0,0158679784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,96",Neutral,1,Damaging,"29,19","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_061,20,31024720,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met1402Arg/c.4205T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9093,184,9318,"0,0197467268",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,96",Neutral,1,Damaging,"29,11","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_062,20,31024720,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met1402Arg/c.4205T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),8658,173,8880,"0,019481982",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,96",Neutral,1,Damaging,"29,13","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_063,20,31024720,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met1402Arg/c.4205T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9003,156,9215,"0,0169289202",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,96",Neutral,1,Damaging,"29,19","15,6"
"low bq, low freq, many artifacts, many samples",UPN2_064,20,31024720,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met1402Arg/c.4205T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),7175,129,7359,"0,0175295556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,96",Neutral,1,Damaging,"29,23","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_065,20,31024720,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met1402Arg/c.4205T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9510,165,9757,"0,0169109357",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,96",Neutral,1,Damaging,"29,32","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_066,20,31024720,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met1402Arg/c.4205T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),10406,165,10634,"0,0155162686",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,96",Neutral,1,Damaging,"29,29","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_067,20,31024720,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met1402Arg/c.4205T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),11306,193,11571,"0,0166796301",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,96",Neutral,1,Damaging,"29,36","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_068,20,31024720,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met1402Arg/c.4205T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9436,173,9687,"0,0178589863",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,96",Neutral,1,Damaging,"29,03","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_069,20,31024720,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met1402Arg/c.4205T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9515,179,9740,"0,0183778234",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,96",Neutral,1,Damaging,"29,11","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_070,20,31024720,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met1402Arg/c.4205T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),6555,141,6744,"0,0209074733",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,96",Neutral,1,Damaging,"29,24","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_071,20,31024720,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met1402Arg/c.4205T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),7105,124,7283,"0,0170259508",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,96",Neutral,1,Damaging,"29,24","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_072,20,31024720,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met1402Arg/c.4205T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),7147,134,7338,"0,0182611066",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,96",Neutral,1,Damaging,"29,33","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_073,20,31024720,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met1402Arg/c.4205T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),7409,125,7574,"0,0165038289",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,96",Neutral,1,Damaging,"29,28","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_074,20,31024720,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met1402Arg/c.4205T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),6718,124,6875,"0,0180363636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,96",Neutral,1,Damaging,"29,21","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_075,20,31024720,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met1402Arg/c.4205T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),10008,174,10236,"0,0169988277",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,96",Neutral,1,Damaging,"29,4","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_076,20,31024720,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met1402Arg/c.4205T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),8239,152,8430,"0,0180308422",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,96",Neutral,1,Damaging,"29,3","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_077,20,31024720,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met1402Arg/c.4205T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),11182,228,11470,"0,0198779425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,96",Neutral,1,Damaging,"29,17","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_078,20,31024720,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met1402Arg/c.4205T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9286,185,9537,"0,0193981336",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,96",Neutral,1,Damaging,"29,17","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_079,20,31024720,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met1402Arg/c.4205T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),5530,110,5674,"0,0193866761",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,96",Neutral,1,Damaging,"29,17","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_080,20,31024720,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met1402Arg/c.4205T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),10527,203,10812,"0,0187754347",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,96",Neutral,1,Damaging,"29,23","15,25"
"low bq, low freq, many artifacts, many samples",UPN2_081,20,31024720,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met1402Arg/c.4205T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),10475,193,10779,"0,017905186",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,96",Neutral,1,Damaging,"29,4","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_082,20,31024720,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met1402Arg/c.4205T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),11811,213,12089,"0,0176193234",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,96",Neutral,1,Damaging,"29,42","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_083,20,31024720,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met1402Arg/c.4205T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),10472,188,10727,"0,0175258693",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,96",Neutral,1,Damaging,"29,18","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_084,20,31024720,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met1402Arg/c.4205T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),11392,199,11668,"0,0170551937",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,96",Neutral,1,Damaging,"29,28","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_085,20,31024720,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met1402Arg/c.4205T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9490,190,9741,"0,0195051843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,96",Neutral,1,Damaging,"29,16","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_086,20,31024720,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met1402Arg/c.4205T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),6339,126,6501,"0,0193816336",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,96",Neutral,1,Damaging,"29,19","15,63"
"low bq, low freq, many artifacts, many samples",UPN2_087,20,31024720,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met1402Arg/c.4205T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),12133,211,12408,"0,017005158",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,96",Neutral,1,Damaging,"29,16","14,99"
"low bq, low freq, many artifacts",UPN2_088,20,31024720,T,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met1402Arg/c.4205T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9211,137,9416,"0,0145497026",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,96",Neutral,1,Damaging,"29,37","15,26"
"low freq, many artifacts",UPN2_006,20,31024728,G,A,missense_variant(MODERATE|MISSENSE|Gtc/Atc|p.Val1405Ile/c.4213G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),4226,47,4281,"0,0109787433",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,36",Neutral,"0,005",Damaging,"33,97","33,21"
"low bq, low freq, many artifacts, many samples",UPN2_062,20,31024729,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1405Gly/c.4214T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),8730,91,8897,"0,0102281668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,34",Neutral,2,Damaging,"31,33","15,53"
"low bq, low freq, many artifacts, many samples",UPN2_070,20,31024729,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1405Gly/c.4214T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),6644,71,6758,"0,0105060669",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,34",Neutral,2,Damaging,"31,39","14,18"
"low bq, low freq, many artifacts, many samples",UPN2_079,20,31024729,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1405Gly/c.4214T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),5585,60,5677,"0,0105689625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,34",Neutral,2,Damaging,"31,34","14,42"
"low bq, low freq, many artifacts",UPN2_086,20,31024729,T,G,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val1405Gly/c.4214T>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),6418,66,6520,"0,0101226994",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,34",Neutral,2,Damaging,"31,27","14,58"
"low freq, many artifacts",UPN2_041,20,31024735,A,G,missense_variant(MODERATE|MISSENSE|gAc/gGc|p.Asp1407Gly/c.4220A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),987,22,1018,"0,021611002",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,92",Deleterious,0,Damaging,"31,91","34,05"
"low freq, many artifacts",UPN2_056,20,31024738,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu1408Ser/c.4223T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3431,52,3499,"0,014861389",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,88",Neutral,0,Damaging,"33,21","33,71"
"low freq, many artifacts",UPN2_044,20,31024744,T,C,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe1410Ser/c.4229T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3023,34,3084,"0,0110246433",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,"0,033",Damaging,"31,88","33,82"
"inspected, many artifacts, many different dels",UPN2_041,20,31024746,TG,T,frameshift_variant(HIGH||tgg/|p.Trp1411fs/c.4233delG|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T|INFO_REALIGN_3_PRIME),974,35,1018,"0,0343811395",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,53",NA
"low bq, low freq, many artifacts",UPN2_086,20,31024762,A,C,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu1416Ala/c.4247A>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6403,70,6509,"0,0107543401",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,52",Deleterious,2,Damaging,"30,23","15,13"
"low freq, many artifacts",UPN2_044,20,31024804,T,C,missense_variant(MODERATE|MISSENSE|cTc/cCc|p.Leu1430Pro/c.4289T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1530,27,1558,"0,0173299101",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,36",Neutral,"0,021",Damaging,"35,35","35,07"
"low freq, many artifacts",UPN2_056,20,31024804,T,C,missense_variant(MODERATE|MISSENSE|cTc/cCc|p.Leu1430Pro/c.4289T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1740,22,1764,"0,0124716553",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,36",Neutral,"0,021",Damaging,"35,28","33,59"
"low freq, many artifacts",UPN2_044,20,31024822,T,TC,frameshift_variant(HIGH||aag/Caag|p.Lys1437fs/c.4308dupC|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|TC|INFO_REALIGN_3_PRIME),4585,50,4627,"0,0108061379",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,38",NA
"low freq, many artifacts",UPN2_044,20,31024858,A,T,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln1448Leu/c.4343A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4556,53,4626,"0,0114569823",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,74",Deleterious,"0,001",Damaging,"35,3","35,51"
"low freq, many artifacts",UPN2_006,20,31024876,T,C,missense_variant(MODERATE|MISSENSE|tTt/tCt|p.Phe1454Ser/c.4361T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),5296,72,5379,"0,0133853876",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,46",Deleterious,0,Damaging,"34,53","35,04"
"low freq, many artifacts",UPN2_056,20,31024902,T,C,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe1463Leu/c.4387T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4593,48,4668,"0,0102827763",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,93",Neutral,"0,054",Tolerated,"34,2","32,17"
"low freq, many artifacts",UPN2_041,20,31024948,C,T,missense_variant(MODERATE|MISSENSE|gCa/gTa|p.Ala1478Val/c.4433C>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),11982,165,12187,"0,013539017",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,7",Neutral,"0,043",Damaging,"32,85","34,19"
"low bq, low freq, many artifacts, many samples",UPN2_059,20,31024963,G,C,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser1483Thr/c.4448G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),31017,444,31540,"0,0140773621",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,04",Damaging,"29,93","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_060,20,31024963,G,C,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser1483Thr/c.4448G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),29742,425,30231,"0,0140584169",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,04",Damaging,"30,01","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_061,20,31024963,G,C,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser1483Thr/c.4448G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),25515,339,25915,"0,0130812271",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,04",Damaging,"29,95","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_062,20,31024963,G,C,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser1483Thr/c.4448G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),23594,281,23932,"0,0117416012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,04",Damaging,"29,96","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_063,20,31024963,G,C,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser1483Thr/c.4448G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),26571,337,26996,"0,0124833309",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,04",Damaging,"29,96","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_064,20,31024963,G,C,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser1483Thr/c.4448G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),27192,353,27612,"0,0127842967",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,04",Damaging,"29,9","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_065,20,31024963,G,C,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser1483Thr/c.4448G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),26513,352,26937,"0,0130675279",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,04",Damaging,"29,85","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_066,20,31024963,G,C,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser1483Thr/c.4448G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),31349,427,31867,"0,0133994414",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,04",Damaging,"29,95","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_067,20,31024963,G,C,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser1483Thr/c.4448G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),30657,381,31118,"0,0122437175",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,04",Damaging,"29,92","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_068,20,31024963,G,C,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser1483Thr/c.4448G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),26811,369,27250,"0,0135412844",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,04",Damaging,"29,97","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_069,20,31024963,G,C,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser1483Thr/c.4448G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),34895,440,35424,"0,0124209575",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,04",Damaging,"29,9","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_070,20,31024963,G,C,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser1483Thr/c.4448G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),21967,271,22297,"0,0121541014",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,04",Damaging,"29,93","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_071,20,31024963,G,C,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser1483Thr/c.4448G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),20193,275,20526,"0,013397642",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,04",Damaging,"29,86","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_072,20,31024963,G,C,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser1483Thr/c.4448G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),21845,289,22188,"0,0130250586",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,04",Damaging,"29,95","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_073,20,31024963,G,C,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser1483Thr/c.4448G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),22975,303,23331,"0,012987013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,04",Damaging,"29,83","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_074,20,31024963,G,C,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser1483Thr/c.4448G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),19320,269,19627,"0,0137056096",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,04",Damaging,"29,96","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_075,20,31024963,G,C,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser1483Thr/c.4448G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),34865,481,35460,"0,0135645798",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,04",Damaging,"29,79","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_076,20,31024963,G,C,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser1483Thr/c.4448G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),27790,357,28202,"0,0126586767",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,04",Damaging,"30,01","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_077,20,31024963,G,C,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser1483Thr/c.4448G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),35231,399,35687,"0,0111805419",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,04",Damaging,"29,98","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_078,20,31024963,G,C,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser1483Thr/c.4448G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),27990,363,28409,"0,0127776409",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,04",Damaging,"29,98","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_079,20,31024963,G,C,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser1483Thr/c.4448G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),19690,260,19990,"0,0130065033",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,04",Damaging,"29,99","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_080,20,31024963,G,C,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser1483Thr/c.4448G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),28273,374,28721,"0,0130218307",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,04",Damaging,"29,89","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_081,20,31024963,G,C,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser1483Thr/c.4448G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),31620,445,32142,"0,0138448136",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,04",Damaging,"29,83","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_082,20,31024963,G,C,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser1483Thr/c.4448G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),33230,453,33756,"0,0134198365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,04",Damaging,"29,86","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_083,20,31024963,G,C,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser1483Thr/c.4448G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),35196,485,35762,"0,0135618813",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,04",Damaging,30,"14,66"
"low bq, low freq, many artifacts, many samples",UPN2_084,20,31024963,G,C,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser1483Thr/c.4448G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),31256,370,31689,"0,0116759759",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,04",Damaging,"29,9","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_085,20,31024963,G,C,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser1483Thr/c.4448G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),24274,325,24661,"0,0131787032",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,04",Damaging,"29,99","14,13"
"low bq, low freq, many artifacts, many samples",UPN2_086,20,31024963,G,C,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser1483Thr/c.4448G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),17471,227,17741,"0,0127952201",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,04",Damaging,"29,99","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_087,20,31024963,G,C,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser1483Thr/c.4448G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),37224,499,37836,"0,0131884977",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,04",Damaging,"29,93","14,28"
"low bq, low freq, many artifacts",UPN2_088,20,31024963,G,C,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser1483Thr/c.4448G>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),29558,390,30030,"0,012987013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,04",Damaging,"29,9","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_041,20,31024966,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His1484Leu/c.4451A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),6110,102,6230,"0,0163723917",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,23",Deleterious,2,Damaging,"33,57","22,35"
"low bq, low freq, many artifacts, many samples",UPN2_042,20,31024966,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His1484Leu/c.4451A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),21174,245,21502,"0,0113942889",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,23",Deleterious,2,Damaging,"33,66","19,33"
"low bq, low freq, many artifacts, many samples",UPN2_043,20,31024966,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His1484Leu/c.4451A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),14137,174,14379,"0,0121009806",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,23",Deleterious,2,Damaging,"33,67","18,1"
"low bq, low freq, many artifacts, many samples",UPN2_044,20,31024966,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His1484Leu/c.4451A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),2957,37,3029,"0,0122152526",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,23",Deleterious,2,Damaging,"33,5","19,08"
"low bq, low freq, many artifacts, many samples",UPN2_047,20,31024966,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His1484Leu/c.4451A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),26278,293,26697,"0,0109750159",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,23",Deleterious,2,Damaging,"33,63","20,39"
"low bq, low freq, many artifacts, many samples",UPN2_049,20,31024966,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His1484Leu/c.4451A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),11816,125,11980,"0,0104340568",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,23",Deleterious,2,Damaging,"33,78","18,7"
"low bq, low freq, many artifacts, many samples",UPN2_051,20,31024966,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His1484Leu/c.4451A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),13454,163,13665,"0,0119282839",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,23",Deleterious,2,Damaging,"33,6","20,21"
"low bq, low freq, many artifacts, many samples",UPN2_053,20,31024966,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His1484Leu/c.4451A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),18750,206,19013,"0,0108346921",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,23",Deleterious,2,Damaging,"33,86","20,17"
"low bq, low freq, many artifacts, many samples",UPN2_055,20,31024966,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His1484Leu/c.4451A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),19826,213,20093,"0,0106007067",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,23",Deleterious,2,Damaging,"33,74","19,41"
"low bq, low freq, many artifacts, many samples",UPN2_057,20,31024966,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His1484Leu/c.4451A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),17534,182,17774,"0,0102396759",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,23",Deleterious,2,Damaging,"33,65","17,55"
"low bq, low freq, many artifacts",UPN2_058,20,31024966,A,T,missense_variant(MODERATE|MISSENSE|cAc/cTc|p.His1484Leu/c.4451A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),16450,181,16685,"0,0108480671",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,23",Deleterious,2,Damaging,"33,63","19,77"
"low freq, many artifacts",UPN2_006,20,31024968,A,T,missense_variant(MODERATE|MISSENSE|Agt/Tgt|p.Ser1485Cys/c.4453A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),5242,65,5326,"0,0122042809",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,23",Deleterious,"0,001",Damaging,"35,08","32,75"
"low freq, many artifacts",UPN2_041,20,31024986,CA,C,frameshift_variant(HIGH||atg/|p.Met1492fs/c.4474delA|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C|INFO_REALIGN_3_PRIME),6073,74,6233,"0,0118722926",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,78",NA
"low bq, low freq, many artifacts",UPN2_047,20,31024988,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln1491His/c.4473A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),26326,271,26711,"0,0101456329",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,35",Deleterious,1,Damaging,"34,12","21,01"
"low freq, many artifacts",UPN2_056,20,31025002,G,T,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser1496Ile/c.4487G>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),4537,56,4600,"0,012173913",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,15",Deleterious,0,Damaging,"35,16","31,91"
"strandbias, many samples",UPN2_001,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),8644,419,9111,"0,0459883657",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,13","31,72"
"strandbias, many samples",UPN2_014,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),14152,326,14558,"0,0223931859",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,54","32,03"
"strandbias, many samples",UPN2_015,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),18732,436,19258,"0,0226399418",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,28","32,05"
"strandbias, many samples",UPN2_016,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9302,218,9564,"0,0227938101",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,37","31,69"
"strandbias, many samples",UPN2_017,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),6032,147,6213,"0,0236600676",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,52","32,2"
"strandbias, many samples",UPN2_018,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9576,238,9846,"0,0241722527",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,47","32,02"
"strandbias, many samples",UPN2_019,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),10946,356,11354,"0,0313545887",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,29","31,82"
"strandbias, many samples",UPN2_020,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9290,257,9600,"0,0267708333",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,39","32,23"
"strandbias, many samples",UPN2_021,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),11119,353,11530,"0,0306157849",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,44","31,92"
"strandbias, many samples",UPN2_002,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),11246,535,11826,"0,0452393032",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,26","31,73"
"strandbias, many samples",UPN2_003,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),2121,88,2218,"0,0396753832",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,43","31,55"
"strandbias, many samples",UPN2_022,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),14012,361,14439,"0,0250017314",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,49","32,12"
"strandbias, many samples",UPN2_023,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),16534,581,17209,"0,0337614039",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,21",32
"strandbias, many samples",UPN2_024,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),6716,132,6884,"0,0191748983",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,56","32,33"
"strandbias, many samples",UPN2_025,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),17049,480,17600,"0,0272727273",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,42","31,71"
"strandbias, many samples",UPN2_026,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),17044,499,17656,"0,0282623471",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,4","31,97"
"strandbias, many samples",UPN2_004,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),1572,71,1652,"0,0429782082",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,26","31,54"
"strandbias, many samples",UPN2_027,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),19281,617,20001,"0,0308484576",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,38","31,73"
"strandbias, many samples",UPN2_089,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),11173,168,11369,"0,0147770252",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,37","32,47"
"strandbias, many samples",UPN2_042,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),24067,290,24557,"0,0118092601",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,05","32,14"
"strandbias, many samples",UPN2_028,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),13807,449,14325,"0,0313438045",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,3","31,88"
"strandbias, many samples",UPN2_043,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),15830,187,16133,"0,0115911486",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,1","32,1"
"strandbias, many samples",UPN2_044,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3512,71,3622,"0,0196024296",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"33,91","32,2"
"strandbias, many samples",UPN2_029,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),16762,627,17478,"0,0358736698",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,27","31,92"
"strandbias, many samples",UPN2_030,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),15400,483,15955,"0,0302726418",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,39","32,21"
"strandbias, many samples",UPN2_031,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),10029,279,10361,"0,0269279027",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,31","31,62"
"strandbias, many samples",UPN2_005,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3801,200,4034,"0,0495785821",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,27","31,84"
"strandbias, many samples",UPN2_032,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),5840,156,6027,"0,0258835241",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,28","31,76"
"strandbias, many samples",UPN2_046,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),21490,348,22023,"0,0158016619",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,08","31,98"
"strandbias, many samples",UPN2_033,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),11299,262,11628,"0,0225318197",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,42","32,15"
"strandbias, many samples",UPN2_034,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),4445,99,4564,"0,0216914987",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,33","31,95"
"strandbias, many samples",UPN2_047,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),31310,472,32019,"0,0147412474",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"33,96","31,97"
"strandbias, many samples",UPN2_035,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),12856,357,13280,"0,0268825301",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,41","31,88"
"strandbias, many samples",UPN2_036,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),13386,424,13880,"0,0305475504",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,32","31,86"
"strandbias, many samples",UPN2_006,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),5792,142,5953,"0,0238535192",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,5","32,09"
"strandbias, many samples",UPN2_049,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),14659,281,15043,"0,0186797846",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"33,79","31,94"
"strandbias, many samples",UPN2_050,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),19962,204,20319,"0,0100398642",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"33,94","32,64"
"strandbias, many samples",UPN2_037,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),23932,681,24739,"0,0275273859",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,36","31,97"
"strandbias, many samples",UPN2_051,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),16976,321,17449,"0,0183964697",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"33,73","31,77"
"strandbias, many samples",UPN2_052,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),16924,225,17279,"0,0130215869",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,06","32,26"
"strandbias, many samples",UPN2_038,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),25860,643,26649,"0,0241284851",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,48","32,02"
"strandbias, many samples",UPN2_039,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),11189,289,11542,"0,025038988",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,45","32,18"
"strandbias, many samples",UPN2_053,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),22346,481,22990,"0,0209221401",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"33,95","32,1"
"strandbias, many samples",UPN2_054,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),15039,234,15372,"0,0152224824",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"33,79","32,25"
"strandbias, many samples",UPN2_007,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),26768,1171,28109,"0,041659255",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,25","31,68"
"strandbias, many samples",UPN2_008,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),32849,1007,34002,"0,0296159049",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,38","31,88"
"strandbias, many samples",UPN2_009,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),27666,936,28768,"0,0325361513",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,28","31,85"
"strandbias, many samples",UPN2_010,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),19919,701,20728,"0,0338189888",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,22","31,62"
"strandbias, many samples",UPN2_011,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),24034,967,25137,"0,0384691888",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,24","31,75"
"strandbias, many samples",UPN2_055,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),23318,371,23850,"0,0155555556",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"33,94","31,78"
"strandbias, many samples",UPN2_056,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),5081,57,5171,"0,011023013",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,21","32,68"
"strandbias, many samples",UPN2_090,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9339,110,9471,"0,0116144019",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,42","31,57"
"strandbias, many samples",UPN2_057,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),21422,426,22046,"0,0193232332",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"33,83","31,99"
"strandbias, many samples",UPN2_058,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),21697,691,22540,"0,0306566105",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"33,68","31,9"
"strandbias, many samples",UPN2_059,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),23005,1296,24403,"0,0531082244",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"33,35","31,52"
"strandbias, many samples",UPN2_012,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),12644,626,13353,"0,0468808507",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,13","31,75"
"strandbias, many samples",UPN2_060,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),17095,415,17620,"0,0235527809",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,03","31,86"
"inspected, strandbias, many samples",UPN2_040,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),8278,154,8472,"0,018177526",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,65","32,02"
"strandbias, many samples",UPN2_013,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),7132,264,7438,"0,0354934122",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,28","31,64"
"strandbias, many samples",UPN2_091,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),8890,126,9033,"0,0139488542",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,49","31,48"
"strandbias, many samples",UPN2_092,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),5929,83,6022,"0,0137827964",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,32","32,46"
"strandbias, many samples",UPN2_093,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),7006,109,7131,"0,0152853737",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,16","32,21"
"strandbias, many samples",UPN2_061,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),15248,525,15868,"0,033085455",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"33,97","31,81"
"strandbias, many samples",UPN2_062,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),13351,320,13743,"0,0232845812",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,07","31,69"
"strandbias, many samples",UPN2_063,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),16926,751,17773,"0,0422551061",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"33,7","31,66"
"strandbias, many samples",UPN2_064,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),15208,327,15608,"0,0209507945",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,18","31,42"
"strandbias, many samples",UPN2_065,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),16982,638,17705,"0,0360350184",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"33,71","31,55"
"strandbias, many samples",UPN2_066,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),28004,2134,30253,"0,070538459",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"32,92","31,47"
"strandbias, many samples",UPN2_067,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),23886,1517,25526,"0,0594296012",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"33,28","31,55"
"strandbias, many samples",UPN2_068,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),18068,772,18929,"0,0407839822",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"33,55","31,44"
"strandbias, many samples",UPN2_069,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),25917,1500,27507,"0,0545315738",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"33,31","31,56"
"strandbias, many samples",UPN2_070,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),14690,641,15387,"0,0416585429",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"33,6","31,43"
"strandbias, many samples",UPN2_071,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),12046,353,12458,"0,0283352063",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"33,94","31,38"
"strandbias, many samples",UPN2_072,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),12337,279,12691,"0,0219840832",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,12","31,43"
"strandbias, many samples",UPN2_073,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),14564,582,15238,"0,0381939887",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"33,79","31,64"
"strandbias, many samples",UPN2_074,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),13717,841,14623,"0,0575121384",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"33,5","31,37"
"strandbias, many samples",UPN2_075,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),22138,925,23151,"0,0399550775",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"33,78","31,48"
"strandbias, many samples",UPN2_076,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),17140,604,17824,"0,0338868941",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"33,88","31,88"
"strandbias, many samples",UPN2_077,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),22369,848,23325,"0,0363558414",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"33,79","31,49"
"strandbias, many samples",UPN2_078,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),19990,1135,21247,"0,0534193063",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"33,45","31,6"
"strandbias, many samples",UPN2_079,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),11629,327,12018,"0,0272091862",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,04","31,64"
"strandbias, many samples",UPN2_080,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),17841,793,18703,"0,042399615",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"33,78","31,71"
"strandbias, many samples",UPN2_081,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),17404,258,17752,"0,0145335737",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,19","31,93"
"strandbias, many samples",UPN2_082,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),24670,1344,26132,"0,0514311955",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"33,36","31,42"
"strandbias, many samples",UPN2_083,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),21022,723,21873,"0,0330544507",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"33,91","31,74"
"strandbias, many samples",UPN2_084,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),19777,702,20575,"0,0341190765",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"33,8","31,54"
"strandbias, many samples",UPN2_085,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),19675,1266,21040,"0,0601711027",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"33,24","31,36"
"strandbias, many samples",UPN2_086,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),19712,1829,21637,"0,0845311272",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"32,59","31,4"
"strandbias, many samples",UPN2_087,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),27007,1536,28666,"0,0535826415",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"33,49","31,53"
"strandbias, many samples",UPN2_088,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),20830,1139,22071,"0,0516061801",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"33,44","31,61"
"strandbias, many samples",UPN2_095,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9809,110,9940,"0,0110663984",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,56","32,49"
"strandbias, many samples",UPN2_098,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),10059,128,10212,"0,0125342734",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,47","32,3"
"strandbias, many samples",UPN2_099,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),5691,80,5784,"0,0138312586",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,57","31,66"
"strandbias, many samples",UPN2_101,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9741,114,9880,"0,0115384615",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,33","31,78"
"strandbias, many samples",UPN2_102,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),9914,109,10044,"0,0108522501",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,5","32,67"
"strandbias, many samples",UPN2_104,20,31025007,A,G,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr1498Ala/c.4492A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),11204,121,11350,"0,010660793",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-0,63",Neutral,"0,332",Tolerated,"34,63","32,12"
"low freq, many artifacts, not in 2nd illumina",UPN2_006,20,31025016,A,G,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser1501Gly/c.4501A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),5862,71,5956,"0,0119207522",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,87",Neutral,"0,042",Damaging,"35,38","35,58"
"bad alignment, strandbias, many samples",UPN2_001,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),7626,1416,9063,"0,1562396557",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,77","31,47"
"bad alignment, strandbias, many samples",UPN2_014,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),12620,1832,14480,"0,126519337",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,36","31,57"
"bad alignment, strandbias, many samples",UPN2_015,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),17452,1694,19193,"0,0882613453",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,61","31,63"
"bad alignment, strandbias, many samples",UPN2_016,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),8432,1054,9513,"0,1107957532",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,5","31,52"
"bad alignment, strandbias, many samples",UPN2_017,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),5420,739,6173,"0,1197148874",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,5","31,76"
"bad alignment, strandbias, many samples",UPN2_018,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),8662,1124,9813,"0,1145419342",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,49","31,58"
"bad alignment, strandbias, many samples",UPN2_019,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),9992,1300,11315,"0,1148917366",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,65","31,64"
"bad alignment, strandbias, many samples",UPN2_020,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),8404,1122,9553,"0,1174500157",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,44","31,56"
"bad alignment, strandbias, many samples",UPN2_021,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),10066,1395,11487,"0,1214416297",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,54","31,57"
"bad alignment, strandbias, many samples",UPN2_002,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),9750,2012,11779,"0,1708124629",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,66","31,5"
"bad alignment, strandbias, many samples",UPN2_003,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1827,379,2211,"0,171415649",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,54","31,63"
"bad alignment, strandbias, many samples",UPN2_022,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),12707,1632,14368,"0,1135857461",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,5","31,4"
"bad alignment, strandbias, many samples",UPN2_023,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),15290,1749,17084,"0,1023764926",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,67","31,52"
"bad alignment, strandbias, many samples",UPN2_024,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6162,661,6842,"0,0966091786",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,37","31,48"
"bad alignment, strandbias, many samples",UPN2_025,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),15412,2036,17503,"0,1163229161",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,54","31,41"
"bad alignment, strandbias, many samples",UPN2_026,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),15515,2041,17593,"0,1160120502",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,58","31,54"
"inspected, bad alignment, strandbias, many samples",UPN2_004,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),1388,262,1654,"0,1584038694",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,77","31,52"
"bad alignment, strandbias, many samples",UPN2_027,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),17441,2409,19904,"0,1210309486",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,62","31,56"
"bad alignment, strandbias, many samples",UPN2_089,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),10870,476,11362,"0,0418940327",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,65","31,57"
"bad alignment, strandbias, many samples",UPN2_042,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),22939,1516,24520,"0,0618270799",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,17","31,35"
"bad alignment, strandbias, many samples",UPN2_028,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),12690,1518,14238,"0,1066160978",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,66","31,46"
"bad alignment, strandbias, many samples",UPN2_043,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),14959,1073,16071,"0,0667662249",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,16","31,28"
many samples,UPN2_044,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3353,246,3610,"0,0681440443",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,1,Damaging,"32,3","31,37"
"bad alignment, strandbias, many samples",UPN2_029,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),15499,1855,17409,"0,1065540812",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,69","31,54"
"bad alignment, strandbias, many samples",UPN2_030,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),14015,1805,15866,"0,1137652843",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,57","31,5"
"bad alignment, strandbias, many samples",UPN2_031,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),9209,1081,10329,"0,1046567916",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,56","31,58"
"bad alignment, strandbias, many samples",UPN2_005,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),3301,703,4007,"0,1754429748",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,67","31,62"
"bad alignment, strandbias, many samples",UPN2_045,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),20992,1088,22111,"0,0492062774",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,14","31,45"
"bad alignment, strandbias, many samples",UPN2_032,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),5389,605,6012,"0,1006320692",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,6","31,69"
"bad alignment, strandbias, many samples",UPN2_046,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),20085,1791,21914,"0,0817285753",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,25","31,5"
"bad alignment, strandbias, many samples",UPN2_033,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),10290,1234,11552,"0,1068213296",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,46","31,55"
"bad alignment, strandbias, many samples",UPN2_034,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4126,430,4567,"0,0941537114",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,48","31,67"
"bad alignment, strandbias, many samples",UPN2_047,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),29812,2109,31980,"0,0659474672",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,36","31,44"
"bad alignment, strandbias, many samples",UPN2_048,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),14017,1270,15320,"0,0828981723",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"31,79","31,31"
"bad alignment, strandbias, many samples",UPN2_035,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),11614,1577,13223,"0,1192618922",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,52","31,54"
"bad alignment, strandbias, many samples",UPN2_036,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),12165,1633,13825,"0,118119349",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,54","31,55"
"bad alignment, strandbias, many samples",UPN2_006,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4868,996,5874,"0,1695607763",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,23","31,52"
"bad alignment, strandbias, many samples",UPN2_049,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),14064,892,14993,"0,0594944307",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,46","31,35"
"bad alignment, strandbias, many samples",UPN2_050,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),19390,839,20269,"0,0413932606",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,2","31,33"
"bad alignment, strandbias, many samples",UPN2_037,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),21972,2636,24668,"0,1068590887",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,55","31,49"
"bad alignment, strandbias, many samples",UPN2_051,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16432,908,17385,"0,052228933",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,54","31,34"
"bad alignment, strandbias, many samples",UPN2_052,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16431,769,17242,"0,0446003944",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,28","31,51"
"bad alignment, strandbias, many samples",UPN2_038,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),23233,3214,26524,"0,121173277",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,45","31,49"
"bad alignment, strandbias, many samples",UPN2_039,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),10115,1366,11511,"0,1186690991",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,46","31,58"
"bad alignment, strandbias, many samples",UPN2_053,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),21212,1647,22923,"0,0718492344",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,37","31,4"
"bad alignment, strandbias, many samples",UPN2_054,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),14513,805,15358,"0,0524156791",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,4","31,09"
"bad alignment, strandbias, many samples",UPN2_007,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),23657,4253,27979,"0,1520068623",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,61","31,44"
"bad alignment, strandbias, many samples",UPN2_008,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),28435,5260,33789,"0,1556719642",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,41","31,42"
"bad alignment, strandbias, many samples",UPN2_009,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),24479,4073,28617,"0,1423279869",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,54","31,48"
"bad alignment, strandbias, many samples",UPN2_010,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),17457,3170,20665,"0,1533994677",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,54","31,42"
"bad alignment, strandbias, many samples",UPN2_011,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),21109,3931,25082,"0,1567259389",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,59","31,49"
"bad alignment, strandbias, many samples",UPN2_055,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),22242,1548,23829,"0,0649628604",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,29","31,4"
"bad alignment, strandbias, many samples",UPN2_056,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),4839,315,5165,"0,0609874153",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,12","31,57"
"bad alignment, strandbias, many samples",UPN2_090,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),9145,299,9460,"0,0316067653",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,59","31,24"
"bad alignment, strandbias, many samples",UPN2_057,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),20333,1551,21939,"0,0706960208",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,43","31,26"
"bad alignment, strandbias, many samples",UPN2_058,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),20548,1844,22435,"0,082193002",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,69","31,33"
"bad alignment, strandbias, many samples",UPN2_059,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),22089,2283,24414,"0,0935119194",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"33,03","31,29"
"bad alignment, strandbias, many samples",UPN2_012,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),11219,2016,13261,"0,1520247342",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,7","31,49"
"bad alignment, strandbias, many samples",UPN2_060,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),15119,2337,17501,"0,1335352266",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,26","31,3"
"bad alignment, strandbias, many samples",UPN2_040,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),7362,1038,8422,"0,1232486345",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,31","31,58"
"bad alignment, strandbias, many samples",UPN2_013,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6229,1135,7378,"0,1538357278",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,56","31,49"
"bad alignment, strandbias, many samples",UPN2_091,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),8530,484,9022,"0,0536466415",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,53","31,59"
"bad alignment, strandbias, many samples",UPN2_092,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),5776,229,6008,"0,0381158455",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,59","31,69"
"bad alignment, strandbias, many samples",UPN2_093,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),6803,275,7090,"0,038787024",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,84","31,16"
"bad alignment, strandbias, many samples",UPN2_061,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),13595,2185,15815,"0,1381599747",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,45","31,37"
"bad alignment, strandbias, many samples",UPN2_062,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),11646,1991,13659,"0,1457646973",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,22","31,15"
"bad alignment, strandbias, many samples",UPN2_063,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),15356,2292,17682,"0,1296233458",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,64","31,35"
"bad alignment, strandbias, many samples",UPN2_064,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),13154,2325,15520,"0,149806701",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,16","31,42"
"bad alignment, strandbias, many samples",UPN2_065,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),15749,1868,17666,"0,1057398392",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,64","31,26"
"bad alignment, strandbias, many samples",UPN2_066,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),27892,2390,30349,"0,0787505354",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"33,46","31,41"
"bad alignment, strandbias, many samples",UPN2_067,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),23043,2369,25478,"0,0929821807",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"33,21","31,47"
"bad alignment, strandbias, many samples",UPN2_068,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16928,1953,18928,"0,1031804734",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,78","31,46"
"bad alignment, strandbias, many samples",UPN2_069,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),24716,2711,27494,"0,0986033316",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"33,04","31,34"
"bad alignment, strandbias, many samples",UPN2_070,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),13602,1713,15360,"0,1115234375",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,78","31,45"
"bad alignment, strandbias, many samples",UPN2_071,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),10804,1584,12409,"0,1276492868",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,34","31,23"
"bad alignment, strandbias, many samples",UPN2_072,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),10865,1742,12627,"0,1379583432",0,1,0,0,1,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,22","31,26"
"bad alignment, strandbias, many samples",UPN2_073,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),13318,1848,15196,"0,1216109503",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,62","31,36"
"bad alignment, strandbias, many samples",UPN2_074,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),12950,1696,14677,"0,1155549499",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,94","31,38"
"bad alignment, strandbias, many samples",UPN2_075,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),20214,2808,23083,"0,121647966",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,63","31,32"
"bad alignment, strandbias, many samples",UPN2_076,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),15421,2283,17743,"0,1286704616",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,49","31,44"
"bad alignment, strandbias, many samples",UPN2_077,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),20542,2635,23223,"0,1134650993",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,62","31,38"
"bad alignment, strandbias, many samples",UPN2_078,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),18984,2239,21261,"0,1053101924",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,97","31,42"
"bad alignment, strandbias, many samples",UPN2_079,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),10368,1545,11946,"0,129331994",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,37","31,3"
"bad alignment, strandbias, many samples",UPN2_080,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16323,2292,18663,"0,1228098376",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,59","31,36"
"bad alignment, strandbias, many samples",UPN2_081,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),15275,2345,17676,"0,1326657615",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,1","31,31"
"bad alignment, strandbias, many samples",UPN2_082,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),23762,2379,26205,"0,0907842015",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"33,05","31,47"
"bad alignment, strandbias, many samples",UPN2_083,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),18833,2881,21769,"0,1323441591",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,4","31,39"
"bad alignment, strandbias, many samples",UPN2_084,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),18182,2316,20542,"0,1127446208",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,61","31,32"
"bad alignment, strandbias, many samples",UPN2_085,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),19178,1817,21042,"0,0863511073",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"33,3","31,43"
"bad alignment, strandbias, many samples",UPN2_086,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),20322,1343,21719,"0,0618352595",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"33,9","31,53"
"bad alignment, strandbias, many samples",UPN2_087,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),25819,2831,28721,"0,0985689913",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"33,03","31,42"
"bad alignment, strandbias, many samples",UPN2_088,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),19542,2501,22108,"0,1131264701",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,91","31,35"
"bad alignment, strandbias, many samples",UPN2_094,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),11141,462,11613,"0,0397830018",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,35","31,33"
"bad alignment, strandbias, many samples",UPN2_095,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),9440,455,9916,"0,0458854377",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,45","31,35"
"bad alignment, strandbias, many samples",UPN2_096,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),9962,411,10387,"0,0395686916",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,29","31,03"
"bad alignment, strandbias, many samples",UPN2_097,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),11733,619,12365,"0,0500606551",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,36","31,5"
"bad alignment, strandbias, many samples",UPN2_098,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),9707,494,10206,"0,0484029003",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,41","31,67"
many samples,UPN2_099,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),5493,280,5779,"0,0484512892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,1,Damaging,"32,43","31,38"
"bad alignment, strandbias, many samples",UPN2_100,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),8253,328,8591,"0,0381794902",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,4","31,8"
"bad alignment, strandbias, many samples",UPN2_101,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),9541,311,9869,"0,0315128179",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,67","31,64"
"bad alignment, strandbias, many samples",UPN2_102,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),9654,382,10051,"0,0380061685",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,51","31,37"
"bad alignment, strandbias, many samples",UPN2_103,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),8781,379,9173,"0,0413169083",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,37","31,34"
"bad alignment, strandbias, many samples",UPN2_104,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),10751,567,11334,"0,050026469",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,36","31,51"
"bad alignment, strandbias, many samples",UPN2_105,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),9678,461,10147,"0,0454321474",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,32","31,77"
"bad alignment, strandbias, many samples",UPN2_106,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),12063,432,12510,"0,0345323741",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,14","31,5"
"bad alignment, strandbias, many samples",UPN2_107,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),16393,705,17111,"0,0412015662",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,3","31,49"
"bad alignment, strandbias, many samples",UPN2_108,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),14046,482,14543,"0,0331430929",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,44","31,64"
"bad alignment, strandbias, many samples",UPN2_109,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),12708,441,13165,"0,0334979111",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,37","31,41"
"bad alignment, strandbias, many samples",UPN2_110,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),13069,379,13465,"0,0281470479",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,2","31,58"
"bad alignment, strandbias, many samples",UPN2_111,20,31025059,T,C,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met1515Thr/c.4544T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),12717,570,13311,"0,0428217264",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,03",Deleterious,"0,001",Damaging,"32,57","31,56"
"inspected, many artifacts",UPN2_081,20,31025068,G,A,missense_variant(MODERATE|MISSENSE|gGc/gAc|p.Gly1518Asp/c.4553G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),1654,22,1682,"0,0130796671",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,39",Deleterious,"0,001",Damaging,"34,62","30,59"
"inspected, many artifacts",UPN2_044,20,31025079,T,C,missense_variant(MODERATE|MISSENSE|Ttc/Ctc|p.Phe1522Leu/c.4564T>C|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|C),554,33,593,"0,0556492411",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,48",Deleterious,"0,001",Damaging,"34,21","35,42"
"inspected, many artifacts",UPN2_049,20,31025086,A,G,missense_variant(MODERATE|MISSENSE|cAc/cGc|p.His1524Arg/c.4571A>G|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|G),3021,35,3064,"0,0114229765",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,32",Deleterious,"0,001",Damaging,"34,55","34,66"
"low freq, many artifacts, many samples",UPN2_057,20,31025122,T,A,stop_gained(HIGH|NONSENSE|tTg/tAg|p.Leu1536*/c.4607T>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),8642,91,8773,"0,0103727345",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,97","28,18"
"inspected, many artifacts",UPN2_040,20,31025125,G,A,missense_variant(MODERATE|MISSENSE|tGc/tAc|p.Cys1537Tyr/c.4610G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),2005,26,2037,"0,0127638684",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,87",Deleterious,0,Damaging,"31,24","34,12"
"inspected, many artifacts",UPN2_044,20,31025130,G,A,missense_variant(MODERATE|MISSENSE|Gtg/Atg|p.Val1539Met/c.4615G>A|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|A),1125,65,1191,"0,0545759866",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,69",Deleterious,0,Damaging,"32,3","32,97"
inspected,UPN2_056,20,31025136,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg1541*/c.4621A>T|1541|ASXL1|protein_coding|CODING|ENST00000375687|13|T),1105,45,1156,"0,0389273356",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,01","31,56"
"low bq, bad alignment, many samples",UPN2_001,21,36164432,T,G,stop_lost(HIGH|MISSENSE|tgA/tgC|p.Ter481Cysext*?/c.1443A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3098,86,3207,"0,0268163393",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,24","14,16"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_015,21,36164432,T,G,stop_lost(HIGH|MISSENSE|tgA/tgC|p.Ter481Cysext*?/c.1443A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6879,90,6995,"0,0128663331",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,64","14,6"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_002,21,36164432,T,G,stop_lost(HIGH|MISSENSE|tgA/tgC|p.Ter481Cysext*?/c.1443A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4283,60,4362,"0,0137551582",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,67","14,42"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_041,21,36164432,T,G,stop_lost(HIGH|MISSENSE|tgA/tgC|p.Ter481Cysext*?/c.1443A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),34256,457,34955,"0,0130739522",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"24,81","14,58"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_025,21,36164432,T,G,stop_lost(HIGH|MISSENSE|tgA/tgC|p.Ter481Cysext*?/c.1443A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6644,135,6798,"0,019858782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,05","14,52"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,21,36164432,T,G,stop_lost(HIGH|MISSENSE|tgA/tgC|p.Ter481Cysext*?/c.1443A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),14993,175,15256,"0,0114708967",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,25","15,41"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_043,21,36164432,T,G,stop_lost(HIGH|MISSENSE|tgA/tgC|p.Ter481Cysext*?/c.1443A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),8715,117,8881,"0,0131741921",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"24,81","14,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_044,21,36164432,T,G,stop_lost(HIGH|MISSENSE|tgA/tgC|p.Ter481Cysext*?/c.1443A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3086,41,3154,"0,0129993659",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"24,66","14,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_029,21,36164432,T,G,stop_lost(HIGH|MISSENSE|tgA/tgC|p.Ter481Cysext*?/c.1443A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5544,63,5636,"0,0111781405",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,02",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_031,21,36164432,T,G,stop_lost(HIGH|MISSENSE|tgA/tgC|p.Ter481Cysext*?/c.1443A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3504,41,3565,"0,0115007013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,64","14,78"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,21,36164432,T,G,stop_lost(HIGH|MISSENSE|tgA/tgC|p.Ter481Cysext*?/c.1443A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),12842,153,13091,"0,0116874188",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,12","14,42"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_032,21,36164432,T,G,stop_lost(HIGH|MISSENSE|tgA/tgC|p.Ter481Cysext*?/c.1443A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2105,47,2165,"0,0217090069",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,16","14,57"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,21,36164432,T,G,stop_lost(HIGH|MISSENSE|tgA/tgC|p.Ter481Cysext*?/c.1443A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),10458,118,10627,"0,0111037922",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,24","14,81"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_034,21,36164432,T,G,stop_lost(HIGH|MISSENSE|tgA/tgC|p.Ter481Cysext*?/c.1443A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1795,31,1834,"0,0169029444",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,43","15,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_048,21,36164432,T,G,stop_lost(HIGH|MISSENSE|tgA/tgC|p.Ter481Cysext*?/c.1443A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),14288,163,14556,"0,0111981314",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"24,96","14,43"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_006,21,36164432,T,G,stop_lost(HIGH|MISSENSE|tgA/tgC|p.Ter481Cysext*?/c.1443A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4280,50,4340,"0,0115207373",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,25","14,14"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,21,36164432,T,G,stop_lost(HIGH|MISSENSE|tgA/tgC|p.Ter481Cysext*?/c.1443A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),8826,97,8970,"0,0108138239",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,36","14,41"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,21,36164432,T,G,stop_lost(HIGH|MISSENSE|tgA/tgC|p.Ter481Cysext*?/c.1443A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),10727,158,10948,"0,0144318597",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"24,93","14,27"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,21,36164432,T,G,stop_lost(HIGH|MISSENSE|tgA/tgC|p.Ter481Cysext*?/c.1443A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),8281,111,8439,"0,0131532172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,08","14,41"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,21,36164432,T,G,stop_lost(HIGH|MISSENSE|tgA/tgC|p.Ter481Cysext*?/c.1443A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),9855,139,10071,"0,0138020058",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"24,96","15,14"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,21,36164432,T,G,stop_lost(HIGH|MISSENSE|tgA/tgC|p.Ter481Cysext*?/c.1443A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),12376,174,12615,"0,0137931034",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"24,96","14,5"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,21,36164432,T,G,stop_lost(HIGH|MISSENSE|tgA/tgC|p.Ter481Cysext*?/c.1443A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6196,76,6298,"0,012067323",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,24","15,24"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_007,21,36164432,T,G,stop_lost(HIGH|MISSENSE|tgA/tgC|p.Ter481Cysext*?/c.1443A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),10549,206,10798,"0,019077607",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,3","14,22"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_008,21,36164432,T,G,stop_lost(HIGH|MISSENSE|tgA/tgC|p.Ter481Cysext*?/c.1443A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),18715,212,18992,"0,0111625948",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,8","14,25"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_009,21,36164432,T,G,stop_lost(HIGH|MISSENSE|tgA/tgC|p.Ter481Cysext*?/c.1443A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),14154,205,14418,"0,0142183382",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,5","14,49"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_010,21,36164432,T,G,stop_lost(HIGH|MISSENSE|tgA/tgC|p.Ter481Cysext*?/c.1443A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6052,118,6200,"0,0190322581",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,31","14,3"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_011,21,36164432,T,G,stop_lost(HIGH|MISSENSE|tgA/tgC|p.Ter481Cysext*?/c.1443A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5648,79,5747,"0,0137463024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,51","14,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,21,36164432,T,G,stop_lost(HIGH|MISSENSE|tgA/tgC|p.Ter481Cysext*?/c.1443A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),13456,195,13722,"0,0142107564",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"24,86","14,41"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,21,36164432,T,G,stop_lost(HIGH|MISSENSE|tgA/tgC|p.Ter481Cysext*?/c.1443A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),8693,106,8830,"0,01200453",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,11",15
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_058,21,36164432,T,G,stop_lost(HIGH|MISSENSE|tgA/tgC|p.Ter481Cysext*?/c.1443A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),7313,80,7432,"0,0107642626",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"24,93","14,82"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_012,21,36164432,T,G,stop_lost(HIGH|MISSENSE|tgA/tgC|p.Ter481Cysext*?/c.1443A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3929,51,3995,"0,0127659574",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,66","15,22"
"low bq, bad alignment, low freq, many artifacts",UPN2_013,21,36164432,T,G,stop_lost(HIGH|MISSENSE|tgA/tgC|p.Ter481Cysext*?/c.1443A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2356,31,2397,"0,0129328327",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,49",14
"inspected, many artifacts",UPN2_090,21,36164439,G,T,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro479His/c.1436C>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),2098,24,2124,"0,011299435",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"34,14","33,46"
"inspected, many artifacts",UPN2_006,21,36164445,C,T,stop_gained(HIGH|NONSENSE|tGg/tAg|p.Trp477*/c.1430G>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),4284,56,4341,"0,0129002534",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,7","30,12"
"low bq, bad alignment, many samples",UPN2_001,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3126,72,3210,"0,0224299065",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"26,69",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_014,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),5505,63,5603,"0,0112439764",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"26,81","14,6"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_015,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6833,114,6998,"0,0162903687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"26,23","14,97"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_016,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3593,51,3654,"0,0139573071",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"26,68","15,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_017,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2285,33,2333,"0,0141448778",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"26,55","15,18"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_018,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2747,31,2789,"0,011115095",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"26,78","15,06"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_019,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4131,47,4208,"0,0111692015",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"26,63","15,11"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_020,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4043,48,4123,"0,0116420082",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"26,55","15,17"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_021,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3917,50,3983,"0,0125533517",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"26,86","14,9"
"low freq, many artifacts, many samples",UPN2_002,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4279,67,4365,"0,01534937",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,27,"14,58"
"low bq, low freq, many artifacts, many samples",UPN2_023,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6109,79,6218,"0,0127050499",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"27,13","14,78"
"low bq, bad alignment, many samples",UPN2_041,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),33925,820,35038,"0,0234031623",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"25,59","15,37"
"low bq, low freq, many artifacts, many samples",UPN2_024,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2375,33,2420,"0,0136363636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"27,02","15,85"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_025,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6623,143,6797,"0,0210386935",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"26,64","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_089,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1898,26,1928,"0,0134854772",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"28,9","15,27"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),14857,280,15281,"0,0183234082",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"26,08","14,7"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_028,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4219,45,4299,"0,0104675506",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"26,71","15,38"
"low bq, bad alignment, many samples",UPN2_043,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),8606,215,8897,"0,024165449",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"25,65","14,88"
"low bq, bad alignment, many samples",UPN2_044,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3052,77,3154,"0,0244134432",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"25,63","14,77"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_029,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),5538,60,5632,"0,0106534091",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"26,97","14,55"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_030,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6049,68,6150,"0,0110569106",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"26,88","14,94"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_031,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3499,51,3568,"0,014293722",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"26,47","15,35"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),12791,245,13123,"0,0186695115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,26,"14,67"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_032,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2108,41,2164,"0,0189463956",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"26,31","14,49"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),10363,215,10650,"0,0201877934",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"26,17","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_033,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4199,51,4276,"0,0119270346",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"27,16","15,04"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_034,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1791,34,1837,"0,0185084377",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"26,01","15,24"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),16803,235,17153,"0,0137002274",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"26,47","14,56"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_048,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),14218,294,14591,"0,0201494072",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"25,99","14,38"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_035,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6926,92,7057,"0,0130367011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"26,22","15,16"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_036,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),7066,100,7221,"0,0138484974",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"26,17","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_006,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4283,45,4341,"0,0103662751",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"27,24","14,4"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),8759,146,8994,"0,0162330443",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"25,95","14,73"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),10655,223,10972,"0,0203244623",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"25,67","15,11"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_037,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),8451,117,8620,"0,0135730858",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"25,88","14,44"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),8197,180,8446,"0,0213118636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"25,94","14,23"
"low bq, bad alignment, many samples",UPN2_052,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),9748,236,10086,"0,0233987706",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"25,68","14,36"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_038,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),9339,141,9517,"0,0148155931",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"25,99","14,4"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_039,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6294,70,6409,"0,0109221407",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"26,9","15,01"
"low bq, bad alignment, many samples",UPN2_053,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),12252,299,12654,"0,023628892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"25,57","14,73"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6133,133,6313,"0,0210676382",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"26,15","15,09"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_007,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),10523,216,10794,"0,0200111173",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"26,34","14,9"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_008,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),18664,248,19002,"0,0130512578",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"26,7","14,47"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_009,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),14120,254,14436,"0,0175949016",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"26,53","14,37"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_010,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6062,116,6203,"0,0187006287",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"26,46","14,86"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_011,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),5643,83,5746,"0,0144448312",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"26,58","14,92"
"low bq, bad alignment, many samples",UPN2_055,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),13339,320,13748,"0,0232761129",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"25,6","14,7"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4157,60,4236,"0,0141643059",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"26,6","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_090,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2077,39,2124,"0,0183615819",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"28,46","14,51"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),8601,181,8848,"0,0204566004",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"25,7","14,34"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_058,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),7221,148,7423,"0,0199380304",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"25,41","14,22"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_012,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3920,57,3997,"0,0142606955",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"26,77","15,49"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_013,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2352,44,2403,"0,0183104453",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"26,69","14,41"
"low bq, many samples",UPN2_091,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2832,64,2907,"0,0220158239",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"28,34","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_092,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1408,21,1435,"0,0146341463",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"28,67","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_095,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2419,33,2464,"0,0133928571",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"28,74","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_096,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1613,31,1651,"0,0187764991",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"28,22","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_097,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1837,30,1877,"0,0159829515",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"28,63",14
"low bq, low freq, many artifacts, many samples",UPN2_098,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2467,36,2518,"0,0142970612",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"28,52","16,19"
"low bq, low freq, many artifacts, many samples",UPN2_101,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1578,28,1610,"0,0173913043",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"28,42","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_102,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2213,42,2260,"0,0185840708",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"28,29","14,48"
"low bq, many samples",UPN2_103,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1959,51,2021,"0,0252350322",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"27,94","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_106,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2232,47,2284,"0,0205779335",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"27,88","15,47"
"low bq, many samples",UPN2_107,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4326,102,4444,"0,0229522952",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"27,76","15,25"
"low bq, many samples",UPN2_108,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3085,72,3168,"0,0227272727",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"28,06","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_109,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2172,41,2222,"0,0184518452",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"28,37","15,22"
"low bq, many samples",UPN2_110,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2755,76,2844,"0,0267229255",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"27,79","15,14"
"low bq, low freq, many artifacts",UPN2_111,21,36164446,A,C,missense_variant(MODERATE|MISSENSE|Tgg/Ggg|p.Trp477Gly/c.1429T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2165,47,2217,"0,0211998196",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,55",Deleterious,0,Damaging,"27,83","14,83"
"low bq, bad alignment, many samples",UPN2_001,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3087,95,3210,"0,0295950156",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,56","14,4"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_014,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),5498,68,5608,"0,012125535",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,88","15,03"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_015,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6854,115,7003,"0,0164215336",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,29","14,79"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_016,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3572,53,3656,"0,0144967177",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,71","14,58"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_017,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2280,38,2334,"0,0162810626",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,94",14
"low bq, low freq, many artifacts, many samples",UPN2_018,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2720,47,2791,"0,0168398424",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"27,14","14,55"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_019,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4131,50,4210,"0,0118764846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,81","14,66"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_020,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4036,60,4123,"0,0145525103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,75","15,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_021,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3890,61,3983,"0,0153150891",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,87","14,66"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_002,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4268,76,4365,"0,0174112257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,54","14,09"
"low bq, low freq, many artifacts, many samples",UPN2_023,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6080,87,6220,"0,0139871383",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"27,08","15,45"
"low bq, bad alignment, many samples",UPN2_041,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),33824,892,35048,"0,0254508103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,15","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_024,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2351,41,2419,"0,0169491525",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"27,03","15,56"
"low bq, bad alignment, many samples",UPN2_025,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6600,159,6798,"0,0233892321",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,83","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_027,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6277,87,6416,"0,0135598504",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"27,14","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_089,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1900,24,1928,"0,0124481328",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"29,51",14
"low bq, bad alignment, many samples",UPN2_042,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),14783,342,15289,"0,0223690235",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,61","14,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_028,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4203,56,4299,"0,0130262852",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,99",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_043,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),8591,195,8898,"0,0219150371",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,23","15,2"
"low bq, bad alignment, many samples",UPN2_044,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2973,86,3157,"0,0272410516",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,18","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_029,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),5505,76,5637,"0,0134823488",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"27,05","14,84"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_030,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6039,75,6152,"0,0121911573",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,86","14,44"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_031,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3495,50,3570,"0,0140056022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,57","14,14"
"low bq, bad alignment, many samples",UPN2_045,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),12692,292,13127,"0,0222442295",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,62","14,82"
"low bq, bad alignment, many samples",UPN2_032,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2102,54,2164,"0,0249537893",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,72","14,26"
"low bq, bad alignment, many samples",UPN2_046,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),10297,239,10651,"0,0224392076",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,54","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_033,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4192,60,4276,"0,0140318054",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"27,04","15,22"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_034,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1791,40,1837,"0,0217746326",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,11","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_047,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),16631,285,17160,"0,0166083916",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"27,11","14,65"
"low bq, bad alignment, many samples",UPN2_048,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),14105,328,14595,"0,0224734498",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,64","14,85"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_035,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6930,97,7062,"0,0137354857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,57","14,71"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_036,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),7042,125,7225,"0,0173010381",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,32","14,1"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_006,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4242,63,4341,"0,0145127851",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,87","14,63"
"low bq, bad alignment, many samples",UPN2_049,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),8695,222,8995,"0,024680378",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,45","15,05"
"low bq, bad alignment, many samples",UPN2_050,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),10593,252,10974,"0,022963368",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,18","15,18"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_037,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),8399,142,8622,"0,0164694966",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,26,"14,18"
"low bq, bad alignment, many samples",UPN2_051,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),8141,201,8454,"0,0237757275",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,59","14,93"
"low bq, bad alignment, many samples",UPN2_052,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),9729,289,10093,"0,0286337065",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"25,94","15,07"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_038,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),9274,170,9517,"0,0178627719",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,14","14,74"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_039,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6288,77,6411,"0,0120106068",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,89","14,49"
"low bq, bad alignment, many samples",UPN2_053,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),12164,324,12657,"0,0255984831",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,1","14,97"
"low bq, bad alignment, many samples",UPN2_054,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6102,141,6313,"0,0223348646",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,56","15,44"
"low bq, bad alignment, many samples",UPN2_007,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),10486,242,10805,"0,0223970384",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,14","14,24"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_008,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),18597,296,19011,"0,0155699332",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,43","14,6"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_009,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),14076,274,14441,"0,0189737553",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,29","14,51"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_010,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6041,129,6205,"0,0207896857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,17","14,95"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_011,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),5634,89,5757,"0,0154594407",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,34","15,08"
"low bq, bad alignment, many samples",UPN2_055,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),13253,342,13750,"0,0248727273",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,11","14,38"
"low freq, many artifacts, many samples",UPN2_056,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4142,64,4237,"0,0151050271",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,27,"14,53"
"low bq, low freq, many artifacts, many samples",UPN2_090,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2046,34,2124,"0,016007533",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"28,6","14,41"
"low bq, bad alignment, many samples",UPN2_057,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),8500,218,8850,"0,0246327684",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,31","14,4"
"low bq, bad alignment, many samples",UPN2_058,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),7146,211,7438,"0,0283678408",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"25,97","14,72"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_012,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3916,67,3997,"0,0167625719",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,56","14,31"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_040,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),8034,103,8216,"0,0125365141",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,84","14,87"
"low bq, bad alignment, many samples",UPN2_013,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2333,55,2404,"0,0228785358",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"26,24","15,11"
"low bq, many samples",UPN2_091,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2834,65,2907,"0,0223598211",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"28,71","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_092,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1404,29,1435,"0,0202090592",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,29,"14,24"
"low bq, low freq, many artifacts, many samples",UPN2_095,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2423,29,2466,"0,0117599351",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"29,3",14
"low bq, low freq, many artifacts, many samples",UPN2_096,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1609,34,1651,"0,0205935796",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"28,92","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_097,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1835,37,1877,"0,0197123069",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"28,71","16,59"
"low bq, low freq, many artifacts, many samples",UPN2_098,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2464,42,2520,"0,0166666667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"28,9","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_102,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2226,30,2260,"0,0132743363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"28,73","15,4"
"low bq, low freq, many artifacts, many samples",UPN2_103,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1968,41,2021,"0,0202869866",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"28,41","14,68"
"low bq, many samples",UPN2_106,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2221,53,2284,"0,0232049037",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"28,27","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_107,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4337,84,4444,"0,0189018902",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"28,1","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_108,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3092,54,3169,"0,0170400757",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"28,17","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_109,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2178,32,2222,"0,0144014401",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"28,96","15,41"
"low bq, low freq, many artifacts, many samples",UPN2_110,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2774,52,2844,"0,0182841069",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"28,06","14,4"
"low bq, low freq, many artifacts",UPN2_111,21,36164448,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val476Gly/c.1427T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2163,43,2217,"0,0193955796",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,12",Deleterious,0,Damaging,"28,3","14,16"
"inspected, many artifacts",UPN2_044,21,36164448,A,G,missense_variant(MODERATE|MISSENSE|gTg/gCg|p.Val476Ala/c.1427T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2973,78,3157,"0,0247070003",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,92",Deleterious,0,Damaging,"26,18","32,74"
"inspected, many artifacts",UPN2_090,21,36164448,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val476Glu/c.1427T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),2046,32,2124,"0,0150659134",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,23",Deleterious,0,Damaging,"28,6","29,22"
"low bq, bad alignment, low freq, many artifacts",UPN2_057,21,36164448,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val476Glu/c.1427T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),8500,99,8850,"0,0111864407",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,23",Deleterious,0,Damaging,"26,31","22,93"
"low bq, low freq, many artifacts, many samples",UPN2_001,21,36164454,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu474Ala/c.1421A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3144,44,3209,"0,0137114366",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,72","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_025,21,36164454,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu474Ala/c.1421A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6695,76,6797,"0,0111814036",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"30,95","15,89"
"low bq, low freq, many artifacts, many samples",UPN2_044,21,36164454,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu474Ala/c.1421A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3110,35,3156,"0,0110899873",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,37",Deleterious,0,Damaging,"29,84","14,37"
"low bq, bad alignment, many samples",UPN2_001,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3101,80,3208,"0,0249376559",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"26,97","14,16"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_015,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6811,120,7004,"0,0171330668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"26,63","15,25"
"low bq, low freq, many artifacts, many samples",UPN2_017,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2283,34,2334,"0,0145672665",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"27,06","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_018,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2731,35,2791,"0,0125403081",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"27,21","15,51"
"low bq, low freq, many artifacts, many samples",UPN2_019,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4132,56,4209,"0,013304823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"27,06","14,46"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_020,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4050,55,4124,"0,0133365664",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"26,92","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_021,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3918,44,3984,"0,0110441767",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"27,18",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_002,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4263,74,4363,"0,0169608068",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"26,96",14
"low bq, low freq, many artifacts, many samples",UPN2_023,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6111,67,6223,"0,0107665113",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"27,08","14,9"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_041,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),34185,585,35066,"0,0166828267",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"26,99","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_024,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2371,26,2419,"0,0107482431",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"27,33",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_025,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6620,126,6799,"0,0185321371",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"26,78","14,1"
"low bq, low freq, many artifacts, many samples",UPN2_042,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),14906,232,15303,"0,0151604261",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"27,52","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_028,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4202,62,4299,"0,0144219586",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"27,18","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_043,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),8692,133,8906,"0,0149337525",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"27,13","14,71"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_044,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3088,50,3157,"0,0158378207",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"26,79","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_029,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),5513,82,5638,"0,0145441646",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"27,27","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_030,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6036,84,6152,"0,0136540962",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"27,11","16,69"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_031,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3493,48,3570,"0,0134453782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"26,77","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_045,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),12861,164,13133,"0,0124876266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"27,4","14,04"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_032,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2105,40,2163,"0,018492834",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"26,62",14
"low bq, low freq, many artifacts, many samples",UPN2_046,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),10412,145,10663,"0,0135984245",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"27,49","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_033,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4198,58,4277,"0,0135609072",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"27,44","14,12"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_034,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1788,31,1837,"0,0168753402",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"26,62",14
"low bq, low freq, many artifacts, many samples",UPN2_047,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),16803,184,17167,"0,0107182385",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"27,89","15,97"
"low bq, low freq, many artifacts, many samples",UPN2_048,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),14294,196,14600,"0,0134246575",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"27,38","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_035,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6917,103,7061,"0,014587169",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"27,22","15,93"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_036,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),7081,96,7222,"0,0132927167",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"26,81","14,07"
"low bq, low freq, many artifacts, many samples",UPN2_006,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4252,62,4341,"0,0142824234",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"27,61","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_049,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),8804,127,9002,"0,014107976",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"27,26","15,31"
"low bq, low freq, many artifacts, many samples",UPN2_050,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),10683,184,10982,"0,0167546895",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"27,01","14,7"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_037,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),8383,156,8623,"0,0180911516",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"26,75","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_051,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),8253,126,8462,"0,0148900969",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"27,22","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_052,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),9835,171,10098,"0,0169340463",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"27,08","15,56"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_038,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),9313,158,9521,"0,0165948955",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"26,81","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_053,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),12330,217,12669,"0,0171284237",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"27,03","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_054,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6173,93,6314,"0,0147291733",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"27,25","15,1"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_007,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),10506,228,10807,"0,0210974368",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"26,88","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_008,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),18576,305,19013,"0,0160416557",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"27,47","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_009,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),14063,275,14443,"0,0190403656",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"27,2","14,27"
"low bq, many samples",UPN2_010,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6021,140,6204,"0,0225660864",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"27,03","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_011,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),5628,93,5757,"0,016154247",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"27,24","14,15"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),13401,253,13761,"0,0183852918",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"26,96","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_056,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4154,62,4244,"0,0146088596",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"27,78",17
"low bq, low freq, many artifacts, many samples",UPN2_057,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),8611,151,8850,"0,0170621469",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"27,46","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_058,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),7226,133,7432,"0,0178955867",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"27,1","15,56"
"low bq, low freq, many artifacts, many samples",UPN2_012,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3904,57,3999,"0,0142535634",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"27,68",14
"low bq, low freq, many artifacts, many samples",UPN2_040,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),8068,99,8218,"0,0120467267",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"27,51","14,62"
"low bq, bad alignment",UPN2_013,21,36164460,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu472Arg/c.1415T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2323,59,2405,"0,0245322245",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,1,Damaging,"26,93","14,81"
"inspected, many artifacts",UPN2_006,21,36164467,C,T,missense_variant(MODERATE|MISSENSE|Gcg/Acg|p.Ala470Thr/c.1408G>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),4263,75,4342,"0,017273146",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,46",Neutral,"0,063",Tolerated,"34,68","28,59"
"low bq, many samples",UPN2_001,21,36164470,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser469Ala/c.1405T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3125,72,3210,"0,0224299065",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,434,Tolerated,"27,92",14
"low bq, low freq, many artifacts, many samples",UPN2_015,21,36164470,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser469Ala/c.1405T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6875,87,7006,"0,0124179275",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,434,Tolerated,"28,19","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_017,21,36164470,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser469Ala/c.1405T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2291,24,2336,"0,0102739726",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,434,Tolerated,"29,02",14
"low bq, low freq, many artifacts, many samples",UPN2_002,21,36164470,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser469Ala/c.1405T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4289,55,4368,"0,0125915751",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,434,Tolerated,"27,96",14
"low bq, low freq, many artifacts, many samples",UPN2_041,21,36164470,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser469Ala/c.1405T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),34266,600,35091,"0,0170984013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,434,Tolerated,"27,93","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_025,21,36164470,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser469Ala/c.1405T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6688,79,6797,"0,0116227748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,434,Tolerated,"28,72","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_042,21,36164470,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser469Ala/c.1405T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),15026,190,15314,"0,0124069479",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,434,Tolerated,"28,57","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_043,21,36164470,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser469Ala/c.1405T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),8711,154,8914,"0,0172761947",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,434,Tolerated,"27,98","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_044,21,36164470,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser469Ala/c.1405T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3084,55,3158,"0,0174160861",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,434,Tolerated,"28,08","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_031,21,36164470,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser469Ala/c.1405T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3510,43,3572,"0,0120380739",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,434,Tolerated,"28,66",14
"low bq, low freq, many artifacts, many samples",UPN2_045,21,36164470,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser469Ala/c.1405T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),12861,189,13138,"0,0143857513",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,434,Tolerated,"28,57","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_032,21,36164470,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser469Ala/c.1405T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2105,34,2163,"0,0157189089",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,434,Tolerated,"28,39","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_046,21,36164470,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser469Ala/c.1405T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),10460,125,10669,"0,0117161871",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,434,Tolerated,"28,52","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_034,21,36164470,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser469Ala/c.1405T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1810,24,1837,"0,0130647795",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,434,Tolerated,"28,27","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_047,21,36164470,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser469Ala/c.1405T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),16866,179,17176,"0,0104215184",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,434,Tolerated,"29,2","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_048,21,36164470,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser469Ala/c.1405T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),14297,206,14606,"0,014103793",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,434,Tolerated,"28,58","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_006,21,36164470,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser469Ala/c.1405T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4254,44,4342,"0,010133579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,434,Tolerated,"28,56","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_049,21,36164470,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser469Ala/c.1405T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),8817,138,9009,"0,0153180153",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,434,Tolerated,"28,51","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_050,21,36164470,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser469Ala/c.1405T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),10740,170,10986,"0,0154742399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,434,Tolerated,"27,88","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_037,21,36164470,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser469Ala/c.1405T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),8459,108,8623,"0,0125246434",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,434,Tolerated,"28,1","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_051,21,36164470,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser469Ala/c.1405T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),8267,118,8473,"0,0139265903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,434,Tolerated,"28,37",14
"low bq, low freq, many artifacts, many samples",UPN2_052,21,36164470,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser469Ala/c.1405T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),9874,183,10106,"0,0181080546",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,434,Tolerated,"27,81","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_053,21,36164470,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser469Ala/c.1405T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),12373,218,12674,"0,0172005681",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,434,Tolerated,"27,78","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_054,21,36164470,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser469Ala/c.1405T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6176,89,6319,"0,014084507",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,434,Tolerated,"28,3","14,08"
"low bq, low freq, many artifacts, many samples",UPN2_007,21,36164470,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser469Ala/c.1405T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),10587,152,10813,"0,0140571534",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,434,Tolerated,"27,04","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_008,21,36164470,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser469Ala/c.1405T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),18704,194,19018,"0,0102008623",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,434,Tolerated,"27,82","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_009,21,36164470,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser469Ala/c.1405T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),14176,207,14471,"0,014304471",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,434,Tolerated,"27,5","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_010,21,36164470,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser469Ala/c.1405T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6070,93,6204,"0,0149903288",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,434,Tolerated,"27,36","14,08"
"low bq, low freq, many artifacts, many samples",UPN2_011,21,36164470,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser469Ala/c.1405T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),5646,77,5756,"0,0133773454",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,434,Tolerated,"27,7","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_055,21,36164470,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser469Ala/c.1405T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),13438,227,13774,"0,0164803253",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,434,Tolerated,"27,83","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_056,21,36164470,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser469Ala/c.1405T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4169,51,4250,"0,012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,434,Tolerated,"28,95","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_057,21,36164470,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser469Ala/c.1405T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),8678,138,8856,"0,0155826558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,434,Tolerated,"28,18","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_058,21,36164470,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser469Ala/c.1405T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),7256,131,7436,"0,0176169984",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,434,Tolerated,"27,57","14,05"
"low bq, low freq, many artifacts, many samples",UPN2_012,21,36164470,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser469Ala/c.1405T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3930,47,4000,"0,01175",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,434,Tolerated,"27,79","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_013,21,36164470,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser469Ala/c.1405T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2359,31,2407,"0,0128791026",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,434,Tolerated,"27,38","14,42"
"low bq, low freq, many artifacts",UPN2_103,21,36164470,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser469Ala/c.1405T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1994,25,2023,"0,0123578843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,434,Tolerated,"29,98",14
"inspected, many artifacts",UPN2_044,21,36164475,G,T,missense_variant(MODERATE|MISSENSE|gCg/gAg|p.Ala467Glu/c.1400C>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),3070,76,3159,"0,0240582463",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,67",Neutral,"0,153",Tolerated,"33,83","25,38"
"low bq, low freq, many artifacts, many samples",UPN2_001,21,36164478,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met466Arg/c.1397T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3145,43,3203,"0,0134249141",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,1,Damaging,"28,38","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_025,21,36164478,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met466Arg/c.1397T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6660,94,6789,"0,0138459272",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,1,Damaging,"29,62","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_043,21,36164478,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met466Arg/c.1397T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),8723,91,8909,"0,0102143899",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,1,Damaging,"29,33","17,56"
"low bq, low freq, many artifacts, many samples",UPN2_032,21,36164478,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met466Arg/c.1397T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2118,27,2159,"0,0125057897",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,1,Damaging,"29,08","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_036,21,36164478,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met466Arg/c.1397T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),7109,74,7222,"0,0102464691",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,1,Damaging,"28,89","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_037,21,36164478,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met466Arg/c.1397T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),8459,90,8617,"0,0104444702",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,1,Damaging,"28,71","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_007,21,36164478,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met466Arg/c.1397T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),10621,111,10800,"0,0102777778",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,1,Damaging,"27,75","14,41"
"low bq, low freq, many artifacts",UPN2_010,21,36164478,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met466Arg/c.1397T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6103,73,6199,"0,0117760929",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,1,Damaging,"27,82","14,7"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_001,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3120,65,3203,"0,0202934749",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"26,84",14
"low bq, low freq, many artifacts, many samples",UPN2_014,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5495,67,5607,"0,011949349",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"27,06",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_015,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6829,116,7003,"0,0165643296",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"26,31","14,78"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_016,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3592,40,3655,"0,0109439124",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"26,78",14
"low bq, low freq, many artifacts, many samples",UPN2_017,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2290,28,2336,"0,0119863014",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"27,06",14
"low bq, low freq, many artifacts, many samples",UPN2_018,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2736,37,2791,"0,0132568972",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"27,11","14,19"
"low bq, low freq, many artifacts, many samples",UPN2_019,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4121,55,4210,"0,013064133",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"27,18","14,49"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_002,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4271,87,4367,"0,0199221433",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"26,87","14,51"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_041,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),34129,677,35081,"0,0192981956",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"26,48","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_024,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2373,27,2417,"0,011170873",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"27,17",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_025,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6664,70,6782,"0,0103214391",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"26,84","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_026,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5383,55,5459,"0,0100751053",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"27,21","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_027,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6286,71,6410,"0,0110764431",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"27,13",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),14959,235,15311,"0,0153484423",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"26,98","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_028,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4206,50,4292,"0,0116495806",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"27,09",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_043,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),8677,160,8912,"0,0179533214",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"26,55","14,44"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_044,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3064,64,3159,"0,0202595758",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"26,35",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_029,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5532,75,5636,"0,0133073101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"26,96","14,47"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_030,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6041,74,6146,"0,0120403514",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"26,85",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_031,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3488,63,3571,"0,0176421171",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"26,74","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_045,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),12833,229,13143,"0,0174237237",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"27,06","15,33"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_032,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2100,41,2160,"0,0189814815",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"26,6","15,07"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),10394,169,10670,"0,0158388004",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"26,88","14,95"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_034,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1788,30,1835,"0,0163487738",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"26,29",14
"low bq, low freq, many artifacts, many samples",UPN2_047,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),16827,220,17177,"0,0128078244",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"27,44","14,35"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_048,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),14258,230,14605,"0,0157480315",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"26,75","14,44"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_035,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6935,77,7055,"0,0109142452",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"26,92","14,09"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_036,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),7057,110,7221,"0,0152333472",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"26,65","14,06"
"low bq, low freq, many artifacts, many samples",UPN2_006,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4231,74,4339,"0,0170546209",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"27,23","14,18"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),8809,120,9002,"0,013330371",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"26,85","14,53"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),10727,190,10979,"0,0173057656",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"26,67","14,49"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_037,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),8457,116,8617,"0,0134617616",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"26,59","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_051,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),8252,145,8474,"0,0171111636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"27,07",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),9848,205,10108,"0,0202809656",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"26,52","14,81"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_038,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),9314,135,9513,"0,0141911069",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"26,61","14,15"
"low bq, low freq, many artifacts, many samples",UPN2_039,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6310,67,6406,"0,0104589447",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"27,37","14,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),12286,269,12669,"0,0212329308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"26,6","14,2"
"low freq, many artifacts, many samples",UPN2_054,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6145,133,6317,"0,0210542979",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,27,"15,23"
"low bq, bad alignment, many samples",UPN2_007,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),10400,322,10797,"0,029823099",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"26,34","14,08"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_008,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),18509,401,19009,"0,0210952707",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"26,72","14,16"
"low bq, bad alignment, many samples",UPN2_009,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),14005,385,14455,"0,0266343826",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"26,51","14,53"
"low bq, bad alignment, many samples",UPN2_010,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5992,169,6197,"0,0272712603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"26,64","14,08"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_011,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5610,116,5757,"0,0201493834",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"26,61","14,38"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),13382,280,13773,"0,0203296304",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"26,5","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_056,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4157,63,4251,"0,0148200423",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"27,42",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),8604,186,8855,"0,0210050819",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"26,67","14,44"
"low bq, bad alignment, many samples",UPN2_058,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),7232,170,7436,"0,0228617536",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"26,31",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_012,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3900,80,3996,"0,02002002",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"26,78",14
"low bq, bad alignment, many samples",UPN2_013,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2327,60,2405,"0,0249480249",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"26,59","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_091,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2856,44,2909,"0,0151254727",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"27,25",14
"low bq, low freq, many artifacts, many samples",UPN2_096,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1621,23,1651,"0,0139309509",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"27,57",14
"low bq, low freq, many artifacts, many samples",UPN2_097,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1848,22,1878,"0,01171459",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"27,23",14
"low bq, low freq, many artifacts, many samples",UPN2_098,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2493,26,2521,"0,0103133677",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"27,79",14
"low bq, low freq, many artifacts, many samples",UPN2_102,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2215,31,2259,"0,0137228862",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"27,42","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_103,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1992,26,2021,"0,0128649184",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"27,21",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_107,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4390,47,4449,"0,0105641717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"26,92","15,49"
"low bq, low freq, many artifacts, many samples",UPN2_109,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2188,27,2220,"0,0121621622",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"27,72",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_110,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2786,46,2844,"0,0161744023",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"26,97","15,39"
"low bq, low freq, many artifacts",UPN2_111,21,36164479,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met466Leu/c.1396A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2169,39,2217,"0,0175913396",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,46",Neutral,1,Tolerated,"27,31",14
"inspected, many artifacts",UPN2_056,21,36164480,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn465Lys/c.1395C>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),4193,48,4252,"0,0112888053",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,"0,309",Tolerated,"33,95","29,48"
"low bq, bad alignment, many samples",UPN2_001,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3055,125,3203,"0,0390259132",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"26,46","14,16"
"low bq, many samples",UPN2_014,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5412,168,5605,"0,0299732382",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"27,1","14,57"
"low bq, bad alignment, many samples",UPN2_015,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6723,249,6999,"0,0355765109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"26,37","14,56"
"low bq, bad alignment, many samples",UPN2_016,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3539,92,3654,"0,0251778872",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"26,61","14,49"
"low bq, bad alignment, many samples",UPN2_017,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2258,65,2336,"0,0278253425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"26,94","14,31"
"low bq, bad alignment, many samples",UPN2_018,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2714,63,2791,"0,0225725546",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"26,73","14,49"
"low bq, bad alignment, many samples",UPN2_019,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4071,111,4209,"0,0263720599",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"26,86","14,68"
"low bq, bad alignment, many samples",UPN2_020,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3974,131,4120,"0,0317961165",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"26,89","14,56"
"low bq, many samples",UPN2_021,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3830,131,3980,"0,0329145729",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"27,1","14,34"
"low bq, bad alignment, many samples",UPN2_002,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4208,146,4366,"0,0334402199",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"26,42","14,47"
"low bq, bad alignment, many samples",UPN2_003,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),721,26,749,"0,0347129506",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"25,79","16,46"
"low bq, low freq, many artifacts, many samples",UPN2_022,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5516,121,5671,"0,0213366249",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"27,36","14,36"
"low bq, many samples",UPN2_023,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6021,184,6222,"0,0295724847",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"27,21","14,42"
"low bq, many samples",UPN2_041,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),33584,1314,35072,"0,0374657847",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"27,11","14,32"
"low bq, many samples",UPN2_024,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2337,68,2416,"0,0281456954",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"27,15","14,29"
"low bq, bad alignment, many samples",UPN2_025,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6484,258,6780,"0,0380530973",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"26,76","14,08"
"low bq, many samples",UPN2_026,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5296,140,5459,"0,0256457227",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"27,11","14,34"
"low bq, bad alignment, many samples",UPN2_004,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1010,31,1045,"0,0296650718",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"26,45",14
"low bq, bad alignment, many samples",UPN2_027,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6217,148,6408,"0,0230961298",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"26,98","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_089,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1892,31,1927,"0,0160871821",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"28,64",14
"low bq, many samples",UPN2_042,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),14750,450,15308,"0,029396394",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"27,49","14,69"
"low bq, bad alignment, many samples",UPN2_028,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4144,127,4291,"0,0295968306",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"26,88","14,64"
"low bq, many samples",UPN2_043,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),8513,335,8913,"0,0375855492",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"27,27","14,54"
"low bq, many samples",UPN2_044,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3007,131,3157,"0,0414950903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"27,2",14
"low bq, many samples",UPN2_029,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5419,182,5634,"0,0323038694",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"27,01","14,45"
"low bq, many samples",UPN2_030,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5957,166,6146,"0,027009437",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"27,05","14,04"
"low bq, bad alignment, many samples",UPN2_031,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3425,135,3569,"0,0378257215",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"26,95","14,46"
"low bq, bad alignment, many samples",UPN2_005,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),935,30,973,"0,0308324769",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"26,46","14,87"
"low bq, many samples",UPN2_045,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),12644,442,13142,"0,0336326282",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"27,33","14,36"
"low bq, bad alignment, many samples",UPN2_032,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2060,87,2160,"0,0402777778",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"26,78","14,37"
"low bq, many samples",UPN2_046,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),10287,335,10667,"0,0314052686",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"27,37","14,24"
"low bq, many samples",UPN2_033,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4139,120,4274,"0,0280767431",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"27,12","14,58"
"low bq, bad alignment, many samples",UPN2_034,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1764,68,1835,"0,0370572207",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"26,53","14,21"
"low bq, many samples",UPN2_047,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),16617,427,17173,"0,0248646131",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"27,93","14,75"
"low bq, many samples",UPN2_048,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),14020,470,14602,"0,0321873716",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"27,51","14,31"
"low bq, bad alignment, many samples",UPN2_035,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6797,209,7053,"0,0296327804",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"26,67","14,07"
"low bq, bad alignment, many samples",UPN2_036,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6946,237,7221,"0,0328209389",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"26,57","14,74"
"low bq, bad alignment, many samples",UPN2_006,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4221,100,4339,"0,023046785",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"26,61","14,44"
"low bq, many samples",UPN2_049,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),8658,289,8999,"0,0321146794",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"27,28","14,2"
"low bq, many samples",UPN2_050,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),10510,407,10977,"0,0370775257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"27,08","14,29"
"low bq, bad alignment, many samples",UPN2_037,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),8271,304,8615,"0,0352872896",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"26,44","14,4"
"low bq, many samples",UPN2_051,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),8120,303,8472,"0,0357648725",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"27,39","14,46"
"low bq, bad alignment, many samples",UPN2_052,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),9662,393,10106,"0,0388877894",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"26,96","14,07"
"low bq, bad alignment, many samples",UPN2_038,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),9143,328,9511,"0,0344863842",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"26,5","14,45"
"low bq, bad alignment, many samples",UPN2_039,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6210,167,6405,"0,0260733802",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"26,99","14,31"
"low bq, bad alignment, many samples",UPN2_053,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),12119,498,12667,"0,0393147549",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"26,9","14,36"
"low bq, many samples",UPN2_054,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6052,218,6317,"0,0345100522",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"27,28","14,45"
"low bq, bad alignment, many samples",UPN2_007,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),10290,475,10796,"0,043997777",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"26,15","14,32"
"low bq, bad alignment, many samples",UPN2_008,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),18262,644,19005,"0,0338858195",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"26,29","14,26"
"low bq, bad alignment, many samples",UPN2_009,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),13834,558,14452,"0,0386105729",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"26,18","14,29"
"low bq, bad alignment, many samples",UPN2_010,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5901,271,6193,"0,0437590828",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"26,13","14,22"
"low bq, bad alignment, many samples",UPN2_011,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5516,207,5755,"0,0359687228",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"26,19","14,25"
"low bq, bad alignment, many samples",UPN2_055,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),13157,545,13770,"0,0395787945",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"26,97","14,39"
"low bq, many samples",UPN2_056,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4127,108,4251,"0,0254057869",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"27,61","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_090,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2079,33,2126,"0,0155221072",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"28,03",14
"low bq, many samples",UPN2_057,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),8503,294,8852,"0,0332128333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"27,09","14,37"
"low bq, bad alignment, many samples",UPN2_058,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),7071,320,7435,"0,0430396772",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"26,86","14,28"
"low bq, bad alignment, many samples",UPN2_012,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3840,138,3994,"0,0345518277",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"26,57","15,46"
"low bq, bad alignment, many samples",UPN2_040,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),7944,235,8219,"0,0285922862",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"26,99","14,23"
"low bq, bad alignment, many samples",UPN2_013,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2293,100,2404,"0,0415973378",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"26,27",14
"low bq, low freq, many artifacts, many samples",UPN2_091,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2844,48,2909,"0,0165005156",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"27,6",14
"low bq, many samples",UPN2_092,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1402,32,1434,"0,0223152022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"28,42",14
"low bq, low freq, many artifacts, many samples",UPN2_093,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1358,24,1385,"0,0173285199",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"28,38","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_095,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2425,42,2467,"0,0170247264",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"28,28","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_096,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1611,27,1650,"0,0163636364",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"27,72","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_097,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1836,31,1878,"0,0165069223",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"27,87","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_098,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2471,40,2521,"0,0158667196",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"28,23",14
"low bq, low freq, many artifacts, many samples",UPN2_101,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1577,25,1613,"0,0154990701",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"27,99",14
"low bq, low freq, many artifacts, many samples",UPN2_102,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2209,45,2259,"0,0199203187",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"28,19",14
"low bq, low freq, many artifacts, many samples",UPN2_103,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1969,39,2021,"0,0192973775",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"27,3",14
"low bq, many samples",UPN2_106,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2223,51,2285,"0,0223194748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"27,62",14
"low bq, many samples",UPN2_107,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4326,107,4449,"0,0240503484",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"27,57",14
"low bq, many samples",UPN2_108,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3091,70,3167,"0,0221029365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"27,39","14,99"
"low bq, many samples",UPN2_109,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2161,52,2220,"0,0234234234",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"28,08","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_110,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2777,61,2842,"0,0214637579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"27,42","14,43"
"low bq, low freq, many artifacts",UPN2_111,21,36164481,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn465Thr/c.1394A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2161,43,2217,"0,0193955796",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,733,Tolerated,"27,44",14
"inspected, many artifacts",UPN2_090,21,36164484,G,A,missense_variant(MODERATE|MISSENSE|aCc/aTc|p.Thr464Ile/c.1391C>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),2099,25,2125,"0,0117647059",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,0,Damaging,"34,49","33,4"
"inspected, many artifacts",UPN2_044,21,36164485,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr464Ala/c.1390A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3044,40,3157,"0,0126702566",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,55",Deleterious,"0,071",Tolerated,"26,73","30,85"
"low bq, bad alignment, many samples",UPN2_001,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3079,115,3203,"0,0359038401",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"24,73","16,99"
"low bq, low freq, many artifacts, many samples",UPN2_014,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5491,88,5600,"0,0157142857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"27,65","19,49"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_015,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6856,111,6998,"0,0158616748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"26,73","16,78"
"low bq, low freq, many artifacts, many samples",UPN2_016,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3580,54,3654,"0,0147783251",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"27,27","19,81"
"low bq, low freq, many artifacts, many samples",UPN2_017,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2292,35,2336,"0,0149828767",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"27,38","16,51"
"low bq, low freq, many artifacts, many samples",UPN2_018,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2730,43,2791,"0,0154066643",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"27,08","20,79"
"low bq, low freq, many artifacts, many samples",UPN2_019,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4115,71,4209,"0,0168686149",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"27,09","19,45"
"low bq, low freq, many artifacts, many samples",UPN2_020,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4029,60,4121,"0,0145595729",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"27,06","20,32"
"low bq, low freq, many artifacts, many samples",UPN2_021,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3908,61,3980,"0,0153266332",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"27,51","17,15"
"low bq, bad alignment, many samples",UPN2_002,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4234,114,4366,"0,0261108566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"24,79","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_023,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6104,89,6221,"0,0143063816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"27,61","17,22"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_041,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),34086,759,35069,"0,0216430466",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"26,71","16,2"
"low bq, low freq, many artifacts, many samples",UPN2_024,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2372,34,2416,"0,0140728477",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"27,69","18,68"
"low bq, many samples",UPN2_025,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6587,151,6777,"0,0222812454",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"27,05","17,65"
"low bq, low freq, many artifacts, many samples",UPN2_026,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5365,72,5456,"0,0131964809",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"27,55","21,17"
"low bq, low freq, many artifacts, many samples",UPN2_027,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6261,103,6408,"0,0160736579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"27,39","20,11"
"low bq, low freq, many artifacts, many samples",UPN2_042,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),14951,272,15307,"0,0177696479",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"27,18","16,9"
"low bq, low freq, many artifacts, many samples",UPN2_028,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4198,65,4289,"0,0151550478",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"27,33",19
"low bq, bad alignment, many samples",UPN2_043,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),8635,237,8913,"0,0265903736",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"26,81","17,23"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_044,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3044,67,3157,"0,0212226798",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"26,73","16,04"
"low bq, low freq, many artifacts, many samples",UPN2_029,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5513,80,5634,"0,014199503",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"27,35","18,14"
"low bq, low freq, many artifacts, many samples",UPN2_030,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6027,78,6146,"0,0126911813",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"27,45","18,4"
"low bq, low freq, many artifacts, many samples",UPN2_031,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3479,62,3569,"0,0173718128",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"27,05","19,65"
"low bq, bad alignment, many samples",UPN2_005,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),939,24,973,"0,0246659815",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"24,93","20,25"
"low bq, low freq, many artifacts, many samples",UPN2_045,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),12774,286,13140,"0,0217656012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"27,08","17,66"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_032,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2105,42,2160,"0,0194444444",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"26,95","15,81"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),10395,228,10663,"0,0213823502",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"26,95","17,61"
"low bq, low freq, many artifacts, many samples",UPN2_033,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4208,54,4274,"0,0126345344",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"27,79","18,2"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_034,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1804,28,1835,"0,0152588556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"26,63","17,14"
"low bq, low freq, many artifacts, many samples",UPN2_047,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),16748,308,17174,"0,0179340864",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"27,64","17,82"
"low bq, low freq, many artifacts, many samples",UPN2_048,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),14213,306,14600,"0,0209589041",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"27,15","17,42"
"low bq, low freq, many artifacts, many samples",UPN2_035,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6909,98,7053,"0,0138947965",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"27,04","18,64"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_036,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),7056,130,7219,"0,0180080344",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"26,78","20,19"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_006,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4243,72,4339,"0,0165936852",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"25,07","14,97"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),8743,188,8997,"0,0208958542",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"26,86","16,36"
"low bq, bad alignment, many samples",UPN2_050,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),10673,249,10978,"0,0226817271",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"26,5","15,93"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_037,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),8425,144,8615,"0,0167150319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"26,43","16,22"
"low bq, bad alignment, many samples",UPN2_051,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),8226,194,8473,"0,0228962587",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"26,89","16,46"
"low bq, bad alignment, many samples",UPN2_052,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),9796,251,10105,"0,0248391885",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"26,31","16,98"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_038,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),9298,153,9507,"0,0160934049",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"26,44","17,17"
"low bq, low freq, many artifacts, many samples",UPN2_039,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6266,102,6405,"0,0159250585",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"27,31","18,68"
"low bq, bad alignment, many samples",UPN2_053,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),12290,297,12663,"0,0234541578",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"26,3","15,93"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6153,135,6314,"0,021381058",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"26,89","16,97"
"low bq, bad alignment, many samples",UPN2_007,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),10365,364,10794,"0,0337224384",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"24,39","15,9"
"low bq, bad alignment, many samples",UPN2_008,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),18471,446,19004,"0,0234687434",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"24,7","15,37"
"low bq, bad alignment, many samples",UPN2_009,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),13954,452,14453,"0,031273784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"24,34","16,1"
"low bq, bad alignment, many samples",UPN2_010,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5975,202,6193,"0,0326174713",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"24,17","15,61"
"low bq, bad alignment, many samples",UPN2_011,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5567,166,5756,"0,0288394719",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"24,54","16,32"
"low bq, bad alignment, many samples",UPN2_055,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),13359,324,13769,"0,0235311206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"26,45","16,07"
"low bq, low freq, many artifacts, many samples",UPN2_056,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4141,78,4251,"0,0183486239",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"27,67","15,4"
"low bq, low freq, many artifacts, many samples",UPN2_090,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2091,24,2124,"0,011299435",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"28,1","16,25"
"low bq, bad alignment, many samples",UPN2_057,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),8603,217,8852,"0,0245142341",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"26,69","16,9"
"low bq, bad alignment, many samples",UPN2_058,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),7217,187,7433,"0,0251580788",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"26,37","17,39"
"low bq, bad alignment, many samples",UPN2_012,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3853,124,3993,"0,0310543451",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"24,98","17,46"
"low bq, low freq, many artifacts, many samples",UPN2_040,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),8035,135,8220,"0,0164233577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"27,49","19,8"
"low bq, bad alignment, many samples",UPN2_013,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2322,74,2404,"0,03078203",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"24,78","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_091,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2849,53,2908,"0,0182255846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"27,57","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_095,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2433,31,2468,"0,012560778",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"28,09","20,74"
"low bq, low freq, many artifacts, many samples",UPN2_096,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1615,24,1649,"0,0145542753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"27,41","16,75"
"low bq, low freq, many artifacts, many samples",UPN2_097,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1850,24,1878,"0,0127795527",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"27,64","20,58"
"low bq, low freq, many artifacts, many samples",UPN2_102,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2221,33,2259,"0,0146082337",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"27,74","18,76"
"low bq, low freq, many artifacts, many samples",UPN2_103,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1977,34,2021,"0,0168233548",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"27,57","20,56"
"low bq, low freq, many artifacts, many samples",UPN2_107,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4386,50,4449,"0,0112384806",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"27,28","16,52"
"low bq, low freq, many artifacts, many samples",UPN2_108,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3107,47,3167,"0,0148405431",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"27,66","17,96"
"low bq, low freq, many artifacts, many samples",UPN2_109,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2187,24,2219,"0,0108156827",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"28,05","15,83"
"low bq, low freq, many artifacts, many samples",UPN2_110,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2786,51,2842,"0,0179451091",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"27,47","17,37"
"low bq, low freq, many artifacts",UPN2_111,21,36164485,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr464Pro/c.1390A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2185,23,2217,"0,0103743798",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,28",Deleterious,1,Damaging,"27,79","17,43"
"low bq, low freq, many artifacts, many samples",UPN2_107,21,36164491,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser462Ala/c.1384T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2221,29,2284,"0,0126970228",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,77,Tolerated,"35,2",14
"low bq, low freq, many artifacts, many samples",UPN2_109,21,36164491,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser462Ala/c.1384T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1123,20,1155,"0,0173160173",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,77,Tolerated,"34,75",14
"low bq, low freq, many artifacts, many samples",UPN2_001,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1627,33,1665,"0,0198198198",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,45","16,21"
"low bq, low freq, many artifacts, many samples",UPN2_014,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2818,55,2911,"0,0188938509",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,76","21,29"
"low bq, low freq, many artifacts, many samples",UPN2_015,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3537,60,3631,"0,0165243735",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,7","16,25"
"low bq, low freq, many artifacts, many samples",UPN2_016,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1847,38,1899,"0,0200105319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,81","18,87"
"low bq, low freq, many artifacts, many samples",UPN2_019,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2128,38,2185,"0,0173913043",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,76","19,95"
"low bq, low freq, many artifacts, many samples",UPN2_020,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2099,43,2165,"0,0198614319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,65","17,07"
"low bq, low freq, many artifacts, many samples",UPN2_021,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2015,33,2067,"0,0159651669",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,91","18,67"
"low bq, many samples",UPN2_002,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2194,54,2268,"0,0238095238",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,6","19,7"
"low bq, low freq, many artifacts, many samples",UPN2_022,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2854,49,2933,"0,0167064439",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,78","19,31"
"low bq, low freq, many artifacts, many samples",UPN2_023,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3117,50,3195,"0,0156494523",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,95","20,3"
"low bq, low freq, many artifacts, many samples",UPN2_041,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),17624,314,18156,"0,0172945583",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,35","19,23"
"low bq, many samples",UPN2_024,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1214,30,1254,"0,023923445",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"35,06","19,27"
"low bq, low freq, many artifacts, many samples",UPN2_025,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3411,56,3508,"0,015963512",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,84","19,89"
"low bq, many samples",UPN2_026,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2740,64,2835,"0,0225749559",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,79","21,67"
"low bq, low freq, many artifacts, many samples",UPN2_027,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3229,52,3313,"0,015695744",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,89","20,23"
"low bq, low freq, many artifacts, many samples",UPN2_042,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),7700,129,7929,"0,0162693908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,4","21,19"
"low bq, low freq, many artifacts, many samples",UPN2_028,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2151,42,2218,"0,0189359784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"35,07","19,24"
"low bq, many samples",UPN2_043,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4491,105,4662,"0,0225225225",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,32","18,32"
"low bq, low freq, many artifacts, many samples",UPN2_044,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1588,30,1649,"0,0181928441",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,22","21,27"
"low bq, low freq, many artifacts, many samples",UPN2_029,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2842,60,2926,"0,02050581",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,81","21,47"
"low bq, low freq, many artifacts, many samples",UPN2_030,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3096,49,3181,"0,015403961",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,94","19,92"
"low bq, low freq, many artifacts, many samples",UPN2_031,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1787,35,1835,"0,0190735695",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"35,12","24,31"
"low bq, low freq, many artifacts, many samples",UPN2_045,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6671,135,6901,"0,0195623823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,3","18,76"
"low bq, low freq, many artifacts, many samples",UPN2_032,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1088,22,1127,"0,0195208518",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,91",18
"low bq, low freq, many artifacts, many samples",UPN2_046,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5355,102,5525,"0,0184615385",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,38","19,02"
"low bq, low freq, many artifacts, many samples",UPN2_033,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2166,37,2232,"0,0165770609",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,73","18,16"
"low bq, low freq, many artifacts, many samples",UPN2_034,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),910,20,942,"0,0212314225",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"35,13","20,6"
"low bq, low freq, many artifacts, many samples",UPN2_047,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),8705,146,8972,"0,0162728489",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,28","21,59"
"low bq, low freq, many artifacts, many samples",UPN2_048,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),7368,117,7563,"0,0154700516",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,29","19,5"
"low bq, low freq, many artifacts, many samples",UPN2_035,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3531,63,3633,"0,0173410405",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,92","19,24"
"low bq, low freq, many artifacts, many samples",UPN2_036,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3633,72,3749,"0,0192051214",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,84","17,18"
"low bq, low freq, many artifacts, many samples",UPN2_006,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2141,34,2207,"0,0154055279",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,74","20,35"
"low bq, low freq, many artifacts, many samples",UPN2_049,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4519,96,4684,"0,0204953032",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,27","21,05"
"low bq, many samples",UPN2_050,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5483,127,5693,"0,0223080977",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,4","21,2"
"low bq, low freq, many artifacts, many samples",UPN2_037,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4309,96,4454,"0,0215536596",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"35,03","18,71"
"low bq, low freq, many artifacts, many samples",UPN2_051,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4266,60,4366,"0,0137425561",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,5","20,88"
"low bq, low freq, many artifacts, many samples",UPN2_052,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5039,78,5197,"0,0150086588",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,5","19,6"
"low bq, many samples",UPN2_038,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4811,126,4984,"0,0252808989",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,84","16,27"
"low bq, low freq, many artifacts, many samples",UPN2_039,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3216,47,3291,"0,0142813734",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"35,06","18,68"
"low bq, low freq, many artifacts, many samples",UPN2_053,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6326,127,6534,"0,0194367922",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,56","17,86"
"low bq, low freq, many artifacts, many samples",UPN2_054,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3160,59,3258,"0,0181092695",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,62","20,86"
"low bq, many samples",UPN2_007,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5433,127,5600,"0,0226785714",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,61","16,54"
"low bq, low freq, many artifacts, many samples",UPN2_008,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),9562,201,9835,"0,020437214",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,73","18,08"
"low bq, low freq, many artifacts, many samples",UPN2_009,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),7237,132,7434,"0,017756255",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,79","18,27"
"low bq, low freq, many artifacts, many samples",UPN2_010,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3116,54,3197,"0,0168908352",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,74","16,81"
"low bq, low freq, many artifacts, many samples",UPN2_011,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2909,57,2988,"0,0190763052",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,61","18,4"
"low bq, low freq, many artifacts, many samples",UPN2_055,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6936,141,7162,"0,0196872382",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,31","18,77"
"low bq, low freq, many artifacts, many samples",UPN2_056,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2185,50,2278,"0,0219490781",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"33,89","17,4"
"low bq, low freq, many artifacts, many samples",UPN2_057,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4429,87,4573,"0,0190247103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,57","17,84"
"low bq, low freq, many artifacts, many samples",UPN2_058,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3727,71,3840,"0,0184895833",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,58","19,41"
"low bq, low freq, many artifacts, many samples",UPN2_012,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1996,31,2038,"0,0152109912",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,76","22,03"
"low bq, low freq, many artifacts, many samples",UPN2_040,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4135,78,4274,"0,018249883",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,85","19,82"
"low bq, many samples",UPN2_013,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1209,29,1245,"0,0232931727",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"34,55","16,28"
"low bq, low freq, many artifacts",UPN2_107,21,36164491,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser462Pro/c.1384T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2221,24,2284,"0,0105078809",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,47",Deleterious,2,Damaging,"35,2","21,46"
"low bq, low freq, many artifacts, many samples",UPN2_043,21,36164491,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser462Thr/c.1384T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),4491,49,4662,"0,0105105105",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,24",Neutral,1,Damaging,"34,32","16,84"
"low bq, low freq, many artifacts, many samples",UPN2_044,21,36164491,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser462Thr/c.1384T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),1588,21,1649,"0,0127349909",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,24",Neutral,1,Damaging,"34,22","16,52"
"low bq, low freq, many artifacts, many samples",UPN2_006,21,36164491,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser462Thr/c.1384T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),2141,29,2207,"0,0131400091",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,24",Neutral,1,Damaging,"34,74","24,28"
"low bq, low freq, many artifacts, many samples",UPN2_049,21,36164491,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser462Thr/c.1384T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),4519,50,4684,"0,0106746371",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,24",Neutral,1,Damaging,"34,27","16,3"
"low bq, low freq, many artifacts, many samples",UPN2_050,21,36164491,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser462Thr/c.1384T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),5483,61,5693,"0,0107149131",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,24",Neutral,1,Damaging,"34,4","16,61"
"low bq, low freq, many artifacts, many samples",UPN2_052,21,36164491,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser462Thr/c.1384T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),5039,53,5197,"0,0101981913",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,24",Neutral,1,Damaging,"34,5","21,62"
"low bq, low freq, many artifacts",UPN2_056,21,36164491,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser462Thr/c.1384T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),2185,31,2278,"0,0136084284",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,24",Neutral,1,Damaging,"33,89","16,23"
"inspected, many artifacts",UPN2_044,21,36164493,T,A,missense_variant(MODERATE|MISSENSE|aAc/aTc|p.Asn461Ile/c.1382A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1552,24,1579,"0,0151994934",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,13",Deleterious,0,Damaging,"33,6","33,08"
"inspected, many artifacts",UPN2_006,21,36164512,C,T,missense_variant(MODERATE|MISSENSE|Gcc/Acc|p.Ala455Thr/c.1363G>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),2126,37,2163,"0,0171058715",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,38",Neutral,"0,06",Tolerated,"35,5","31,22"
"inspected, many artifacts",UPN2_044,21,36164520,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val452Glu/c.1355T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),1539,33,1579,"0,0208993034",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,71",Neutral,"0,024",Damaging,"34,1","28,97"
"inspected, many artifacts",UPN2_006,21,36164521,C,T,missense_variant(MODERATE|MISSENSE|Gtg/Atg|p.Val452Met/c.1354G>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),2133,28,2163,"0,0129449838",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,72",Neutral,"0,012",Damaging,"35,36",36
"low freq, many artifacts, many samples",UPN2_001,21,36164526,C,G,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser450Thr/c.1349G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2479,37,2521,"0,0146767156",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,197,Tolerated,"34,11","31,7"
"low freq, many artifacts, many samples",UPN2_014,21,36164526,C,G,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser450Thr/c.1349G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4933,82,5025,"0,016318408",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,197,Tolerated,"33,77","31,65"
"low freq, many artifacts, many samples",UPN2_015,21,36164526,C,G,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser450Thr/c.1349G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),7403,76,7496,"0,0101387407",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,197,Tolerated,"33,44","31,58"
"low freq, many artifacts, many samples",UPN2_016,21,36164526,C,G,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser450Thr/c.1349G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3386,46,3438,"0,013379872",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,197,Tolerated,"33,66",32
"low freq, many artifacts, many samples",UPN2_017,21,36164526,C,G,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser450Thr/c.1349G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2282,33,2322,"0,0142118863",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,197,Tolerated,"33,61","31,67"
"low freq, many artifacts, many samples",UPN2_018,21,36164526,C,G,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser450Thr/c.1349G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3188,49,3239,"0,015128126",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,197,Tolerated,"33,28","31,63"
"low freq, many artifacts, many samples",UPN2_019,21,36164526,C,G,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser450Thr/c.1349G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3943,71,4021,"0,0176572992",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,197,Tolerated,"33,68",32
"low freq, many artifacts, many samples",UPN2_020,21,36164526,C,G,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser450Thr/c.1349G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3276,45,3324,"0,0135379061",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,197,Tolerated,34,"31,2"
"low freq, many artifacts, many samples",UPN2_021,21,36164526,C,G,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser450Thr/c.1349G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3655,52,3710,"0,0140161725",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,197,Tolerated,"33,83","31,31"
"low freq, many artifacts, many samples",UPN2_002,21,36164526,C,G,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser450Thr/c.1349G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3106,50,3162,"0,0158127767",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,197,Tolerated,"34,29","31,64"
"low freq, many artifacts, many samples",UPN2_022,21,36164526,C,G,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser450Thr/c.1349G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5211,67,5284,"0,012679788",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,197,Tolerated,"33,73","31,24"
"inspected, strandbias, many samples",UPN2_023,21,36164526,C,G,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser450Thr/c.1349G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5532,70,5609,"0,0124799429",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,197",Tolerated,"33,8","31,49"
"low freq, many artifacts, many samples",UPN2_024,21,36164526,C,G,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser450Thr/c.1349G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2359,28,2390,"0,0117154812",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,197,Tolerated,"33,55","30,71"
"low freq, many artifacts, many samples",UPN2_025,21,36164526,C,G,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser450Thr/c.1349G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6688,73,6780,"0,0107669617",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,197,Tolerated,"33,61","31,36"
"low freq, many artifacts, many samples",UPN2_026,21,36164526,C,G,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser450Thr/c.1349G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5148,70,5241,"0,0133562297",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,197,Tolerated,"33,68","31,67"
"low freq, many artifacts, many samples",UPN2_027,21,36164526,C,G,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser450Thr/c.1349G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5775,92,5876,"0,0156569095",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,197,Tolerated,"33,78","31,25"
"strandbias, many samples",UPN2_028,21,36164526,C,G,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser450Thr/c.1349G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3943,56,4007,"0,0139755428",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,197",Tolerated,"33,77","31,75"
"low freq, many artifacts, many samples",UPN2_029,21,36164526,C,G,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser450Thr/c.1349G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4641,63,4710,"0,0133757962",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,197,Tolerated,"33,98","31,14"
"low freq, many artifacts, many samples",UPN2_030,21,36164526,C,G,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser450Thr/c.1349G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6067,80,6154,"0,012999675",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,197,Tolerated,"33,61","31,51"
"low freq, many artifacts, many samples",UPN2_031,21,36164526,C,G,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser450Thr/c.1349G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3987,47,4042,"0,011627907",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,197,Tolerated,"33,38","31,77"
"low freq, many artifacts, many samples",UPN2_032,21,36164526,C,G,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser450Thr/c.1349G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1981,24,2005,"0,0119700748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,197,Tolerated,"33,66","31,25"
"low freq, many artifacts, many samples",UPN2_033,21,36164526,C,G,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser450Thr/c.1349G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4034,45,4089,"0,0110051357",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,197,Tolerated,"33,68","31,36"
"low freq, many artifacts, many samples",UPN2_034,21,36164526,C,G,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser450Thr/c.1349G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1695,20,1718,"0,0116414435",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,197,Tolerated,"33,76",32
"low freq, many artifacts, many samples",UPN2_035,21,36164526,C,G,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser450Thr/c.1349G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6693,105,6825,"0,0153846154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,197,Tolerated,"33,65","31,69"
"low freq, many artifacts, many samples",UPN2_036,21,36164526,C,G,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser450Thr/c.1349G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5708,68,5784,"0,0117565698",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,197,Tolerated,34,"30,68"
"low freq, many artifacts, many samples",UPN2_006,21,36164526,C,G,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser450Thr/c.1349G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3072,53,3127,"0,0169491525",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,197,Tolerated,"34,34",32
"low freq, many artifacts, many samples",UPN2_037,21,36164526,C,G,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser450Thr/c.1349G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),8140,127,8280,"0,0153381643",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,197,Tolerated,"33,69","31,49"
"strandbias, many samples",UPN2_038,21,36164526,C,G,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser450Thr/c.1349G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),8857,122,9004,"0,0135495335",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,197",Tolerated,"33,72","31,11"
"low freq, many artifacts, many samples",UPN2_039,21,36164526,C,G,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser450Thr/c.1349G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5983,88,6075,"0,0144855967",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,197,Tolerated,"33,74","31,3"
"low freq, many artifacts, many samples",UPN2_007,21,36164526,C,G,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser450Thr/c.1349G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),7565,77,7651,"0,0100640439",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,197,Tolerated,"34,27","31,25"
"low freq, many artifacts, many samples",UPN2_010,21,36164526,C,G,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser450Thr/c.1349G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4221,47,4274,"0,0109967244",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,197,Tolerated,"34,32","30,85"
"low freq, many artifacts, many samples",UPN2_011,21,36164526,C,G,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser450Thr/c.1349G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4472,67,4549,"0,0147285118",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,197,Tolerated,"34,04","31,13"
"low freq, many artifacts, many samples",UPN2_058,21,36164526,C,G,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser450Thr/c.1349G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6755,72,6844,"0,0105201636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,197,Tolerated,"33,49","30,14"
"strandbias, many samples",UPN2_012,21,36164526,C,G,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser450Thr/c.1349G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3120,58,3188,"0,0181932246",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,"0,197",Tolerated,"34,04","31,4"
"low freq, many artifacts, many samples",UPN2_040,21,36164526,C,G,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser450Thr/c.1349G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6376,69,6468,"0,0106679035",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,197,Tolerated,"34,11","30,7"
"low freq, many artifacts",UPN2_013,21,36164526,C,G,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser450Thr/c.1349G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1699,21,1725,"0,012173913",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,197,Tolerated,"34,19","30,29"
"low freq, many artifacts",UPN2_090,21,36164531,G,C,missense_variant(MODERATE|MISSENSE|aaC/aaG|p.Asn448Lys/c.1344C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1975,22,2001,"0,0109945027",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,94",Deleterious,124,Tolerated,"35,59","34,64"
"low freq, many artifacts",UPN2_044,21,36164531,GT,G,frameshift_variant(HIGH||aac/|p.Asn448fs/c.1343delA|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2256,35,2299,"0,0152240104",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,18",NA
"low freq, many artifacts",UPN2_006,21,36164536,G,T,missense_variant(MODERATE|MISSENSE|Ccg/Acg|p.Pro447Thr/c.1339C>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),3082,47,3132,"0,0150063857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,48",Deleterious,45,Damaging,"35,5","34,13"
"low freq, many artifacts",UPN2_006,21,36164540,GC,G,frameshift_variant(HIGH||agc/|p.Ser445fs/c.1334delG|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3085,43,3132,"0,0137292465",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,4",NA
"inspected, many artifacts, many samples",UPN2_018,21,36164542,TG,T,frameshift_variant(HIGH||ccc/|p.Ser445fs/c.1332delC|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),3228,34,3265,"0,0104134763",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,42",NA
"inspected, many artifacts, many samples",UPN2_047,21,36164542,TG,T,frameshift_variant(HIGH||ccc/|p.Ser445fs/c.1332delC|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),13678,152,13885,"0,0109470652",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,16",NA
"inspected, many artifacts, many samples",UPN2_006,21,36164542,TG,T,frameshift_variant(HIGH||ccc/|p.Ser445fs/c.1332delC|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),3090,41,3132,"0,0130906769",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,54",NA
"inspected, many artifacts, many samples",UPN2_011,21,36164542,TG,T,frameshift_variant(HIGH||ccc/|p.Ser445fs/c.1332delC|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),4510,50,4571,"0,0109385255",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,53",NA
"inspected, many artifacts, many samples",UPN2_090,21,36164542,TG,T,frameshift_variant(HIGH||ccc/|p.Ser445fs/c.1332delC|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),1964,36,2002,"0,017982018",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,24",NA
"inspected, many artifacts, many samples",UPN2_081,21,36164542,TG,T,frameshift_variant(HIGH||ccc/|p.Ser445fs/c.1332delC|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),183,23,206,"0,1116504854",0,1,0,0,0,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,11",NA
"low freq, many artifacts, many samples",UPN2_102,21,36164542,TG,T,frameshift_variant(HIGH||ccc/|p.Ser445fs/c.1332delC|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),2340,42,2389,"0,0175805776",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,44",NA
"inspected, many artifacts, many samples",UPN2_108,21,36164542,TG,T,frameshift_variant(HIGH||ccc/|p.Ser445fs/c.1332delC|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),4133,54,4201,"0,0128540824",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,41",NA
many samples,UPN2_111,21,36164542,TG,T,frameshift_variant(HIGH||ccc/|p.Ser445fs/c.1332delC|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),2595,59,2662,"0,0221637866",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,39",NA
"low freq, many artifacts, many samples",UPN2_001,21,36164557,CG,C,frameshift_variant(HIGH||tcc/|p.Ala440fs/c.1317delC|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2495,28,2534,"0,0110497238",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,5",NA
"low freq, many artifacts, many samples",UPN2_020,21,36164557,CG,C,frameshift_variant(HIGH||tcc/|p.Ala440fs/c.1317delC|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3289,38,3335,"0,0113943028",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,37",NA
"low freq, many artifacts, many samples",UPN2_021,21,36164557,CG,C,frameshift_variant(HIGH||tcc/|p.Ala440fs/c.1317delC|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3686,44,3737,"0,0117741504",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,45",NA
"low freq, many artifacts, many samples",UPN2_041,21,36164557,CG,C,frameshift_variant(HIGH||tcc/|p.Ala440fs/c.1317delC|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),26878,318,27286,"0,0116543282",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,08",NA
"low freq, many artifacts, many samples",UPN2_044,21,36164557,CG,C,frameshift_variant(HIGH||tcc/|p.Ala440fs/c.1317delC|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2209,27,2303,"0,0117238385",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,08",NA
"low freq, many artifacts, many samples",UPN2_045,21,36164557,CG,C,frameshift_variant(HIGH||tcc/|p.Ala440fs/c.1317delC|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),9705,139,9877,"0,0140730991",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,15",NA
"low freq, many artifacts, many samples",UPN2_048,21,36164557,CG,C,frameshift_variant(HIGH||tcc/|p.Ala440fs/c.1317delC|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),12648,164,12844,"0,0127686079",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,08",NA
"low freq, many artifacts, many samples",UPN2_049,21,36164557,CG,C,frameshift_variant(HIGH||tcc/|p.Ala440fs/c.1317delC|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),7649,111,7784,"0,0142600206",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,07",NA
"low freq, many artifacts, many samples",UPN2_050,21,36164557,CG,C,frameshift_variant(HIGH||tcc/|p.Ala440fs/c.1317delC|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),8073,117,8223,"0,0142283838",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,99",NA
"low freq, many artifacts, many samples",UPN2_052,21,36164557,CG,C,frameshift_variant(HIGH||tcc/|p.Ala440fs/c.1317delC|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),7881,157,8069,"0,0194571818",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,16",NA
"low freq, many artifacts, many samples",UPN2_007,21,36164557,CG,C,frameshift_variant(HIGH||tcc/|p.Ala440fs/c.1317delC|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),7570,127,7722,"0,0164465164",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,51",NA
"low freq, many artifacts, many samples",UPN2_008,21,36164557,CG,C,frameshift_variant(HIGH||tcc/|p.Ala440fs/c.1317delC|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),12169,195,12399,"0,0157270748",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,56",NA
"low freq, many artifacts, many samples",UPN2_009,21,36164557,CG,C,frameshift_variant(HIGH||tcc/|p.Ala440fs/c.1317delC|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),9604,125,9755,"0,0128139416",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,57",NA
"low freq, many artifacts, many samples",UPN2_055,21,36164557,CG,C,frameshift_variant(HIGH||tcc/|p.Ala440fs/c.1317delC|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),11284,128,11461,"0,0111683099",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,12",NA
"low freq, many artifacts, many samples",UPN2_090,21,36164557,CG,C,frameshift_variant(HIGH||tcc/|p.Ala440fs/c.1317delC|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2033,34,2081,"0,0163382989",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,11",NA
"low freq, many artifacts, many samples",UPN2_040,21,36164557,CG,C,frameshift_variant(HIGH||tcc/|p.Ala440fs/c.1317delC|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6429,85,6525,"0,0130268199",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,54",NA
"low freq, many artifacts, many samples",UPN2_093,21,36164557,CG,C,frameshift_variant(HIGH||tcc/|p.Ala440fs/c.1317delC|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1390,22,1416,"0,0155367232",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,18",NA
"low freq, many artifacts",UPN2_095,21,36164557,CG,C,frameshift_variant(HIGH||tcc/|p.Ala440fs/c.1317delC|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2469,29,2509,"0,0115583898",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,25",NA
"bad alignment, strandbias, many samples",UPN2_001,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2203,297,2504,"0,1186102236",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"32,29","31,68"
"bad alignment, strandbias, many samples",UPN2_014,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4589,427,5027,"0,0849413169",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"33,04","31,75"
"bad alignment, strandbias, many samples",UPN2_015,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),7062,420,7515,"0,0558882236",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"33,31","31,8"
"bad alignment, strandbias, many samples",UPN2_016,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3197,237,3441,"0,0688753269",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"33,08","31,92"
"bad alignment, strandbias, many samples",UPN2_017,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2155,157,2320,"0,0676724138",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"33,39","31,6"
"bad alignment, strandbias, many samples",UPN2_018,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3036,204,3253,"0,0627113434",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"33,63","31,89"
"bad alignment, strandbias, many samples",UPN2_019,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3700,308,4018,"0,0766550523",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"33,2","31,57"
"bad alignment, strandbias, many samples",UPN2_020,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3022,281,3312,"0,0848429952",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"32,63","31,69"
"bad alignment, strandbias, many samples",UPN2_021,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3391,316,3719,"0,0849690777",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"33,09","31,77"
"bad alignment, strandbias, many samples",UPN2_002,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2636,483,3128,"0,1544117647",1,1,0,0,1,1,0,0,4,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"31,72","31,9"
"bad alignment, strandbias, many samples",UPN2_003,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),497,77,576,"0,1336805556",1,1,0,0,1,1,0,0,4,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"32,23","31,91"
"bad alignment, strandbias, many samples",UPN2_022,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4908,356,5281,"0,0674114751",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"33,02","31,62"
"bad alignment, strandbias, many samples",UPN2_023,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),5173,435,5621,"0,0773883651",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"33,01","31,53"
"bad alignment, strandbias, many samples",UPN2_041,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),25809,1192,27101,"0,0439836168",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"32,28","31,63"
"bad alignment, strandbias, many samples",UPN2_024,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2239,146,2398,"0,0608840701",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"33,17","31,75"
"bad alignment, strandbias, many samples",UPN2_025,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6277,506,6798,"0,074433657",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"33,24","31,71"
"bad alignment, strandbias, many samples",UPN2_026,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4854,352,5231,"0,0672911489",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"33,15","31,84"
"inspected, bad alignment, strandbias, many samples",UPN2_004,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),600,119,724,"0,1643646409",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"31,27","31,55"
"bad alignment, strandbias, many samples",UPN2_027,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),5393,500,5918,"0,0844880027",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"32,99","31,85"
"bad alignment, strandbias, many samples",UPN2_089,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2022,58,2080,"0,0278846154",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"33,54","31,34"
"bad alignment, strandbias, many samples",UPN2_042,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),12068,605,12701,"0,0476340446",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"32,47","31,61"
"bad alignment, strandbias, many samples",UPN2_028,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3721,278,4004,"0,0694305694",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"33,11","31,87"
"bad alignment, strandbias, many samples",UPN2_043,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6927,342,7304,"0,0468236583",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"32,49","31,8"
"inspected, bad alignment, strandbias, many samples",UPN2_044,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2143,149,2298,"0,0648389904",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"32,1","31,87"
"bad alignment, strandbias, many samples",UPN2_029,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4324,378,4722,"0,0800508259",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"32,83","31,62"
"bad alignment, strandbias, many samples",UPN2_030,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),5675,449,6151,"0,0729962608",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"33,32","31,88"
"bad alignment, strandbias, many samples",UPN2_031,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3818,232,4057,"0,0571851122",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"33,52","31,66"
"bad alignment, strandbias, many samples",UPN2_005,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),633,106,742,"0,1428571429",0,1,0,0,1,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"31,66","31,83"
"bad alignment, strandbias, many samples",UPN2_045,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),9450,369,9843,"0,0374885706",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"32,08","31,68"
"bad alignment, strandbias, many samples",UPN2_032,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1874,122,2008,"0,0607569721",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"33,21","31,71"
"bad alignment, strandbias, many samples",UPN2_046,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),8539,537,9099,"0,0590174744",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"32,53","31,7"
"bad alignment, strandbias, many samples",UPN2_033,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3816,269,4098,"0,0656417765",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"33,13","31,54"
"bad alignment, strandbias, many samples",UPN2_034,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1616,100,1720,"0,0581395349",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"33,15","31,68"
"bad alignment, strandbias, many samples",UPN2_047,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),13089,716,13844,"0,0517191563",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"32,28","31,67"
"bad alignment, strandbias, many samples",UPN2_048,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),12044,632,12732,"0,0496387056",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"32,66","31,57"
"bad alignment, strandbias, many samples",UPN2_035,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6301,507,6839,"0,0741336453",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"33,1","31,84"
"bad alignment, strandbias, many samples",UPN2_036,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),5261,501,5779,"0,0866931995",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"32,53","31,77"
"bad alignment, strandbias, many samples",UPN2_006,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2677,421,3106,"0,1355441082",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"31,7","31,68"
"bad alignment, strandbias, many samples",UPN2_049,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),7296,429,7754,"0,0553262832",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"32,33","31,67"
"bad alignment, strandbias, many samples",UPN2_050,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),7872,274,8177,"0,0335086217",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"31,84","31,45"
"bad alignment, strandbias, many samples",UPN2_037,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),7658,601,8286,"0,0725319817",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"32,97","31,75"
"bad alignment, strandbias, many samples",UPN2_051,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),7438,287,7757,"0,0369988398",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"32,49","31,6"
"bad alignment, strandbias, many samples",UPN2_052,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),7714,296,8028,"0,0368709517",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"32,13","31,78"
"bad alignment, strandbias, many samples",UPN2_038,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),8335,654,9020,"0,0725055432",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"33,03","31,73"
"bad alignment, strandbias, many samples",UPN2_039,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),5595,469,6081,"0,0771254728",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"33,06","31,8"
"bad alignment, strandbias, many samples",UPN2_053,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),10047,575,10653,"0,053975406",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"32,2","31,71"
"bad alignment, strandbias, many samples",UPN2_054,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),5304,217,5544,"0,0391414141",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"32,35","31,59"
"bad alignment, strandbias, many samples",UPN2_007,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6665,969,7655,"0,1265839321",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"31,82","31,74"
"bad alignment, strandbias, many samples",UPN2_008,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),10506,1776,12323,"0,1441207498",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"31,47","31,72"
"bad alignment, strandbias, many samples",UPN2_009,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),8375,1276,9680,"0,1318181818",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"31,6","31,67"
"bad alignment, strandbias, many samples",UPN2_010,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3695,575,4282,"0,1342830453",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"31,72","31,52"
"bad alignment, strandbias, many samples",UPN2_011,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3959,592,4566,"0,1296539641",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"32,29","31,87"
"bad alignment, strandbias, many samples",UPN2_055,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),10784,567,11401,"0,0497324796",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"32,24","31,69"
"bad alignment, strandbias, many samples",UPN2_056,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3856,140,4008,"0,0349301397",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"32,55","31,68"
"bad alignment, strandbias, many samples",UPN2_090,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2032,43,2081,"0,0206631427",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"33,33","32,28"
"bad alignment, strandbias, many samples",UPN2_057,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6519,413,6968,"0,0592709529",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"32,17","31,69"
"bad alignment, strandbias, many samples",UPN2_058,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6424,420,6874,"0,0610997963",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"32,65","31,77"
"bad alignment, strandbias, many samples",UPN2_012,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2813,366,3187,"0,1148415438",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"32,2","31,75"
"bad alignment, strandbias, many samples",UPN2_040,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),5898,573,6488,"0,0883168927",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"32,6","31,69"
"bad alignment, strandbias, many samples",UPN2_013,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1491,228,1727,"0,1320208454",0,1,0,0,1,1,0,0,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"32,19","31,57"
"bad alignment, strandbias, many samples",UPN2_091,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2659,102,2767,"0,0368630286",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"33,35","31,84"
many samples,UPN2_092,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1239,36,1276,"0,0282131661",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,57,Tolerated,"33,12","31,5"
"bad alignment, strandbias, many samples",UPN2_093,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1370,43,1415,"0,0303886926",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"33,47","32,28"
"bad alignment, strandbias, many samples",UPN2_094,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1813,21,1840,"0,0114130435",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"34,35","32,05"
"bad alignment, strandbias, many samples",UPN2_095,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2418,81,2504,"0,0323482428",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"33,42","32,04"
"bad alignment, strandbias, many samples",UPN2_096,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2442,41,2485,"0,016498994",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"34,06","32,05"
"bad alignment, strandbias, many samples",UPN2_097,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2781,64,2850,"0,0224561404",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"34,19","31,86"
"bad alignment, strandbias, many samples",UPN2_098,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2581,84,2667,"0,031496063",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"33,46","31,62"
many samples,UPN2_099,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1169,33,1206,"0,0273631841",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,57,Tolerated,"33,9",32
"low freq, many artifacts, many samples",UPN2_100,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1954,21,1978,"0,0106167846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,57,Tolerated,"34,12","32,19"
"bad alignment, strandbias, many samples",UPN2_101,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1762,47,1820,"0,0258241758",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"33,6","32,43"
"bad alignment, strandbias, many samples",UPN2_102,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2325,58,2388,"0,0242881072",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"33,34","31,97"
"bad alignment, strandbias, many samples",UPN2_103,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2387,52,2444,"0,0212765957",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"33,48","32,12"
"bad alignment, strandbias, many samples",UPN2_104,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2045,43,2092,"0,0205544933",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"34,4","31,3"
"bad alignment, strandbias, many samples",UPN2_105,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1301,23,1327,"0,0173323286",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"34,44","32,7"
"bad alignment, strandbias, many samples",UPN2_106,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3783,55,3840,"0,0143229167",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"34,15","32,15"
"bad alignment, strandbias, many samples",UPN2_107,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4676,106,4790,"0,0221294363",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"33,47","31,72"
"bad alignment, strandbias, many samples",UPN2_108,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4100,81,4184,"0,0193594646",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"33,88","32,12"
"bad alignment, strandbias, many samples",UPN2_109,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2932,63,3006,"0,0209580838",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"33,75","32,51"
"bad alignment, strandbias, many samples",UPN2_110,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3840,52,3898,"0,0133401744",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,"0,057",Tolerated,"33,89","32,42"
"low freq, many artifacts",UPN2_111,21,36164578,T,C,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr433Ala/c.1297A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2601,57,2661,"0,0214205186",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,99",Deleterious,57,Tolerated,"33,61",32
"low freq, many artifacts",UPN2_036,21,36164584,G,A,missense_variant(MODERATE|MISSENSE|Ccc/Tcc|p.Pro431Ser/c.1291C>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),2168,24,2197,"0,0109239873",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,6",Deleterious,342,Tolerated,"35,32","34,75"
"Not in 2nd illumina, inspected, many artifacts",UPN2_006,21,36164587,G,T,missense_variant(MODERATE|MISSENSE|Ccg/Acg|p.Pro430Thr/c.1288C>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),942,23,969,"0,0237358101",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,05",Deleterious,"0,147",Tolerated,"35,21","33,74"
"inspected, many artifacts",UPN2_011,21,36164593,T,A,missense_variant(MODERATE|MISSENSE|Atc/Ttc|p.Ile428Phe/c.1282A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1678,20,1700,"0,0117647059",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,36",Neutral,"0,002",Damaging,"34,76","30,4"
"inspected, many artifacts!",UPN2_051,21,36164601,G,A,missense_variant(MODERATE|MISSENSE|cCg/cTg|p.Pro425Leu/c.1274C>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),3351,179,3532,"0,0506795017",0,0,0,0,1,0,0,1,2,NO,NO,COSM87293,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-7,53",Deleterious,0,Damaging,"32,99","31,89"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_108,21,36164604,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser424Trp/c.1271C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2496,31,2528,"0,0122626582",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,0,Damaging,"26,4","14,58"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_109,21,36164604,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser424Trp/c.1271C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1792,23,1825,"0,0126027397",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,46",Deleterious,0,Damaging,"26,31",14
"low bq, bad alignment, many samples",UPN2_017,21,36164605,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser424Ala/c.1270T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),406,244,850,"0,2870588235",1,0,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,34",Neutral,3,Damaging,"15,83","14,15"
"low bq, bad alignment, many samples",UPN2_003,21,36164605,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser424Ala/c.1270T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),71,26,145,"0,1793103448",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,34",Neutral,3,Damaging,"15,23",14
"low bq, many samples, no database",UPN2_089,21,36164605,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser424Ala/c.1270T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),587,379,1010,"0,3752475248",1,0,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,34",Neutral,"0,003",Damaging,"15,07","14,14"
"low bq, bad alignment, many samples",UPN2_042,21,36164605,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser424Ala/c.1270T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1132,775,3160,"0,2452531646",1,0,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,34",Neutral,3,Damaging,"17,18","14,1"
"low bq, bad alignment, many samples",UPN2_052,21,36164605,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser424Ala/c.1270T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),640,447,1816,"0,2461453744",1,0,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,34",Neutral,3,Damaging,"17,21","14,2"
"low bq, bad alignment, many samples",UPN2_054,21,36164605,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser424Ala/c.1270T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),494,354,1466,"0,241473397",1,0,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,34",Neutral,3,Damaging,"17,21",14
"low bq, bad alignment, many samples",UPN2_090,21,36164605,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser424Ala/c.1270T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),541,291,879,"0,3310580205",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,34",Neutral,3,Damaging,"15,51","14,04"
"low bq, bad alignment, many samples",UPN2_057,21,36164605,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser424Ala/c.1270T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),556,400,1554,"0,2574002574",1,0,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,34",Neutral,3,Damaging,"16,99","14,2"
"low bq, bad alignment, many samples",UPN2_060,21,36164605,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser424Ala/c.1270T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),85,65,155,"0,4193548387",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,34",Neutral,3,Damaging,"16,4",14
"low bq, bad alignment, many samples",UPN2_091,21,36164605,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser424Ala/c.1270T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),751,405,1234,"0,3282009724",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,34",Neutral,3,Damaging,"15,13","14,11"
"low bq, bad alignment, many samples",UPN2_092,21,36164605,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser424Ala/c.1270T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),287,202,517,"0,3907156673",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,34",Neutral,3,Damaging,"15,1","14,12"
"low bq, bad alignment, many samples",UPN2_093,21,36164605,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser424Ala/c.1270T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),370,255,662,"0,3851963746",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,34",Neutral,3,Damaging,"14,79","14,09"
"low bq, bad alignment, many samples",UPN2_061,21,36164605,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser424Ala/c.1270T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),54,28,87,"0,3218390805",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,34",Neutral,3,Damaging,"16,22",14
"low bq, bad alignment, many samples",UPN2_062,21,36164605,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser424Ala/c.1270T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),40,28,75,"0,3733333333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,34",Neutral,3,Damaging,"17,35","14,25"
"low bq, bad alignment, many samples",UPN2_063,21,36164605,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser424Ala/c.1270T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),85,40,138,"0,2898550725",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,34",Neutral,3,Damaging,"15,69","14,32"
"low bq, bad alignment, many samples",UPN2_071,21,36164605,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser424Ala/c.1270T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),140,85,243,"0,3497942387",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,34",Neutral,3,Damaging,"15,81","14,24"
"low bq, bad alignment, many samples",UPN2_072,21,36164605,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser424Ala/c.1270T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),127,84,227,"0,3700440529",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,34",Neutral,3,Damaging,"16,1","14,24"
"low bq, bad alignment, many samples",UPN2_075,21,36164605,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser424Ala/c.1270T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),62,44,113,"0,389380531",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,34",Neutral,3,Damaging,"15,77","14,5"
"low bq, bad alignment, many samples",UPN2_078,21,36164605,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser424Ala/c.1270T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),100,62,168,"0,369047619",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,34",Neutral,3,Damaging,"15,2","14,65"
"low bq, bad alignment, many samples",UPN2_080,21,36164605,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser424Ala/c.1270T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),113,73,197,"0,3705583756",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,34",Neutral,3,Damaging,"14,94",14
"low bq, bad alignment, many samples",UPN2_081,21,36164605,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser424Ala/c.1270T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),125,59,194,"0,3041237113",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,34",Neutral,3,Damaging,"15,38","14,24"
"low bq, many samples, no database",UPN2_094,21,36164605,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser424Ala/c.1270T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),719,435,1241,"0,3505237712",1,0,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,34",Neutral,"0,003",Damaging,"15,23","14,07"
"low bq, bad alignment, many samples",UPN2_095,21,36164605,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser424Ala/c.1270T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),692,423,1186,"0,3566610455",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,34",Neutral,3,Damaging,"15,17","14,12"
"low bq, bad alignment, many samples",UPN2_096,21,36164605,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser424Ala/c.1270T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),882,558,1536,"0,36328125",1,0,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,34",Neutral,3,Damaging,"15,24","14,23"
"low bq, bad alignment, many samples",UPN2_097,21,36164605,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser424Ala/c.1270T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1074,604,1775,"0,3402816901",1,0,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,34",Neutral,3,Damaging,"15,2","14,17"
"low bq, bad alignment, many samples",UPN2_098,21,36164605,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser424Ala/c.1270T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),788,458,1318,"0,3474962064",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,34",Neutral,3,Damaging,"15,15","14,07"
"low bq, bad alignment, many samples",UPN2_099,21,36164605,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser424Ala/c.1270T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),407,228,668,"0,3413173653",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,34",Neutral,3,Damaging,"15,36","14,11"
"low bq, bad alignment, many samples",UPN2_100,21,36164605,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser424Ala/c.1270T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),723,451,1233,"0,3657745337",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,34",Neutral,3,Damaging,"15,3","14,16"
"low bq, bad alignment, many samples",UPN2_101,21,36164605,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser424Ala/c.1270T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),577,330,964,"0,3423236515",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,34",Neutral,3,Damaging,"15,24","14,13"
"low bq, bad alignment, many samples",UPN2_102,21,36164605,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser424Ala/c.1270T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),679,431,1184,"0,3640202703",1,0,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,34",Neutral,3,Damaging,"15,1","14,16"
"low bq, bad alignment, many samples",UPN2_103,21,36164605,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser424Ala/c.1270T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),801,436,1331,"0,3275732532",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,34",Neutral,3,Damaging,"14,99","14,13"
"low bq, bad alignment, many samples",UPN2_105,21,36164605,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser424Ala/c.1270T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),543,312,910,"0,3428571429",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,34",Neutral,3,Damaging,"15,14","14,26"
"low bq, bad alignment, many samples",UPN2_106,21,36164605,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser424Ala/c.1270T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1467,873,2489,"0,3507432704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,34",Neutral,3,Damaging,"15,22","14,1"
"low bq, bad alignment, many samples",UPN2_108,21,36164605,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser424Ala/c.1270T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1463,811,2428,"0,3340197694",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,34",Neutral,3,Damaging,"15,04","14,11"
"low bq, bad alignment, many samples",UPN2_109,21,36164605,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser424Ala/c.1270T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1030,604,1734,"0,3483275663",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,34",Neutral,3,Damaging,"15,14","14,07"
"low bq, bad alignment",UPN2_111,21,36164605,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser424Ala/c.1270T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),866,507,1445,"0,3508650519",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,34",Neutral,3,Damaging,"15,3","14,04"
"low bq, bad alignment, many samples",UPN2_003,21,36164605,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser424Pro/c.1270T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),71,48,145,"0,3310344828",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,75,Tolerated,"15,23","14,6"
"low bq, bad alignment, many samples",UPN2_022,21,36164605,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser424Pro/c.1270T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),842,433,1812,"0,2389624724",1,0,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,75,Tolerated,"15,82","14,35"
"low bq, bad alignment, many samples",UPN2_089,21,36164605,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser424Pro/c.1270T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),587,42,1010,"0,0415841584",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,75,Tolerated,"15,07","15,05"
"low bq, bad alignment, many samples",UPN2_043,21,36164605,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser424Pro/c.1270T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),626,620,1740,"0,3563218391",1,0,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,75,Tolerated,"16,61","14,37"
"low bq, bad alignment, many samples",UPN2_045,21,36164605,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser424Pro/c.1270T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),656,783,1923,"0,4071762871",0,0,0,0,0,0,1,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,75,Tolerated,"16,94","14,33"
"low bq, bad alignment, many samples",UPN2_032,21,36164605,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser424Pro/c.1270T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),328,163,691,"0,2358900145",1,0,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,75,Tolerated,"15,93","14,13"
"low bq, bad alignment, many samples",UPN2_046,21,36164605,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser424Pro/c.1270T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),765,997,2406,"0,4143807149",0,0,0,0,0,0,1,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,75,Tolerated,"16,19","14,25"
"low bq, bad alignment, many samples",UPN2_034,21,36164605,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser424Pro/c.1270T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),297,148,618,"0,2394822006",1,0,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,75,Tolerated,"15,29","14,3"
"low bq, bad alignment, many samples",UPN2_047,21,36164605,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser424Pro/c.1270T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1133,1211,3165,"0,3826224329",1,0,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,75,Tolerated,"16,9","14,17"
"low bq, bad alignment, many samples",UPN2_035,21,36164605,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser424Pro/c.1270T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1231,588,2487,"0,2364294331",1,0,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,75,Tolerated,"15,9","14,26"
"low bq, bad alignment, many samples",UPN2_050,21,36164605,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser424Pro/c.1270T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),595,652,1706,"0,3821805393",0,0,0,0,0,0,1,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,75,Tolerated,"16,48","14,4"
"low bq, bad alignment, many samples",UPN2_052,21,36164605,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser424Pro/c.1270T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),640,724,1816,"0,3986784141",0,0,0,0,0,0,1,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,75,Tolerated,"17,21","14,47"
"low bq, bad alignment, many samples",UPN2_007,21,36164605,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser424Pro/c.1270T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),938,482,1729,"0,2787738577",1,0,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,75,Tolerated,"15,49","14,2"
"low bq, bad alignment, many samples",UPN2_011,21,36164605,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser424Pro/c.1270T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),716,382,1316,"0,2902735562",1,0,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,75,Tolerated,"15,86","14,23"
"low bq, many samples, no database",UPN2_055,21,36164605,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser424Pro/c.1270T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),965,1123,2785,"0,4032315978",1,0,0,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,"0,075",Tolerated,"17,25","14,26"
"low bq, bad alignment, many samples",UPN2_090,21,36164605,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser424Pro/c.1270T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),541,47,879,"0,0534698521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,75,Tolerated,"15,51","14,47"
"low bq, bad alignment, many samples",UPN2_058,21,36164605,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser424Pro/c.1270T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),690,688,1856,"0,3706896552",1,0,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,75,Tolerated,"16,99","14,37"
"low bq, bad alignment, many samples",UPN2_012,21,36164605,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser424Pro/c.1270T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),467,295,922,"0,3199566161",1,0,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,75,Tolerated,"15,31","14,17"
"low bq, bad alignment, many samples",UPN2_091,21,36164605,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser424Pro/c.1270T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),751,78,1234,"0,0632090762",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,75,Tolerated,"15,13","15,41"
"low bq, bad alignment, many samples",UPN2_092,21,36164605,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser424Pro/c.1270T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),287,28,517,"0,0541586074",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,75,Tolerated,"15,1","15,57"
"low bq, bad alignment, many samples",UPN2_093,21,36164605,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser424Pro/c.1270T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),370,37,662,"0,0558912387",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,75,Tolerated,"14,79",14
"low bq, bad alignment, many samples",UPN2_094,21,36164605,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser424Pro/c.1270T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),719,86,1241,"0,0692989525",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,75,Tolerated,"15,23",14
"low bq, bad alignment, many samples",UPN2_095,21,36164605,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser424Pro/c.1270T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),692,69,1186,"0,0581787521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,75,Tolerated,"15,17","15,59"
"low bq, many samples, no database",UPN2_098,21,36164605,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser424Pro/c.1270T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),788,71,1318,"0,0538694992",1,0,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,"0,075",Tolerated,"15,15","14,62"
"low bq, bad alignment, many samples",UPN2_099,21,36164605,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser424Pro/c.1270T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),407,33,668,"0,0494011976",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,75,Tolerated,"15,36","15,33"
"low bq, bad alignment, many samples",UPN2_100,21,36164605,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser424Pro/c.1270T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),723,58,1233,"0,0470397405",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,75,Tolerated,"15,3","14,6"
"low bq, bad alignment, many samples",UPN2_101,21,36164605,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser424Pro/c.1270T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),577,57,964,"0,0591286307",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,75,Tolerated,"15,24",14
"low bq, bad alignment, many samples",UPN2_103,21,36164605,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser424Pro/c.1270T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),801,93,1331,"0,0698722765",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,75,Tolerated,"14,99","14,71"
"low bq, bad alignment, many samples",UPN2_105,21,36164605,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser424Pro/c.1270T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),543,55,910,"0,0604395604",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,75,Tolerated,"15,14","15,6"
"low bq, bad alignment, many samples",UPN2_106,21,36164605,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser424Pro/c.1270T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1467,148,2489,"0,0594616312",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,75,Tolerated,"15,22","14,42"
"low bq, bad alignment, many samples",UPN2_108,21,36164605,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser424Pro/c.1270T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1463,153,2428,"0,063014827",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,75,Tolerated,"15,04","14,98"
"low bq, bad alignment, many samples",UPN2_109,21,36164605,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser424Pro/c.1270T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1030,98,1734,"0,0565167243",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,75,Tolerated,"15,14","14,45"
"low bq, bad alignment",UPN2_111,21,36164605,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser424Pro/c.1270T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),866,71,1445,"0,0491349481",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,75,Tolerated,"15,3","14,62"
"low bq, bad alignment, low freq, many artifacts",UPN2_049,21,36164607,C,A,missense_variant(MODERATE|MISSENSE|cGc/cTc|p.Arg423Leu/c.1268G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1981,22,2011,"0,0109398309",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,09",Deleterious,2,Damaging,"23,06","25,64"
"Inspected, many artifacts, bad alignment!",UPN2_055,21,36164607,C,T,missense_variant(MODERATE|MISSENSE|cGc/cAc|p.Arg423His/c.1268G>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),2721,28,2760,"0,0101449275",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,"0,004",Damaging,"23,03","35,14"
"low bq, bad alignment, low freq, many artifacts",UPN2_011,21,36164608,G,A,missense_variant(MODERATE|MISSENSE|Cgc/Tgc|p.Arg423Cys/c.1267C>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1258,21,1298,"0,0161787365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,94",Deleterious,1,Damaging,"22,58","25,48"
"low bq, bad alignment, many samples",UPN2_014,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1581,37,1619,"0,0228536133",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"19,09",14
"low bq, bad alignment, many samples",UPN2_015,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2876,75,2967,"0,0252780586",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"19,43","14,47"
"low bq, bad alignment, many samples",UPN2_016,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1122,40,1164,"0,0343642612",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"18,98","14,55"
"low bq, bad alignment, many samples",UPN2_018,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1279,36,1317,"0,0273348519",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"19,55",14
"low bq, bad alignment, many samples",UPN2_019,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1382,44,1432,"0,030726257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"19,24",14
"low bq, bad alignment, many samples",UPN2_020,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),874,25,906,"0,027593819",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"19,55",14
"low bq, bad alignment, many samples",UPN2_022,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1745,41,1790,"0,0229050279",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"19,4","14,54"
"low bq, bad alignment, many samples",UPN2_023,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1800,43,1847,"0,0232809962",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"19,58","14,51"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_041,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),5649,126,5811,"0,021683015",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"21,88","14,1"
"low bq, bad alignment, many samples",UPN2_025,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2403,67,2475,"0,0270707071",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"19,32",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_026,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1848,39,1890,"0,0206349206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"19,92","15,13"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_027,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1938,38,1980,"0,0191919192",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"19,58",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3009,63,3091,"0,0203817535",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"22,21","14,7"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_043,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1650,35,1698,"0,0206124853",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"21,8",15
"low bq, bad alignment, many samples",UPN2_029,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1328,34,1366,"0,0248901903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"19,59",14
"low bq, bad alignment, many samples",UPN2_030,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2120,66,2191,"0,0301232314",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"19,65",14
"low bq, bad alignment, many samples",UPN2_031,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1577,44,1622,"0,0271270037",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"19,73",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1843,40,1893,"0,0211304807",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"21,81","15,43"
"low bq, bad alignment, many samples",UPN2_046,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2286,56,2355,"0,0237791932",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"21,67",14
"low bq, bad alignment, many samples",UPN2_033,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1356,33,1391,"0,0237239396",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"19,35","14,67"
"low bq, bad alignment, many samples",UPN2_047,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3001,72,3098,"0,0232408005",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"22,04","14,1"
"low bq, bad alignment, many samples",UPN2_048,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3195,74,3281,"0,0225540994",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"21,71","15,19"
"low bq, bad alignment, many samples",UPN2_035,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2349,77,2431,"0,0316742081",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"19,8","14,29"
"low bq, bad alignment, many samples",UPN2_036,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1551,40,1592,"0,0251256281",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"19,25",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1951,32,1988,"0,0160965795",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"21,94","14,41"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1643,22,1671,"0,013165769",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"21,89","15,41"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_037,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2806,58,2873,"0,0201879568",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"19,65","14,31"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2162,44,2215,"0,0198645598",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"22,56","14,5"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1752,26,1784,"0,014573991",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"22,39","15,38"
"low bq, bad alignment, many samples",UPN2_038,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3073,79,3160,"0,025",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"19,56",14
"low bq, bad alignment, many samples",UPN2_039,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2025,49,2085,"0,023501199",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"19,54","14,82"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2523,53,2595,"0,0204238921",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"21,68","14,42"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1415,22,1442,"0,0152565881",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"22,16",15
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_007,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1666,33,1706,"0,0193434936",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"22,24",14
"low bq, bad alignment, many samples",UPN2_008,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2119,49,2173,"0,0225494708",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"22,36",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_009,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1859,22,1888,"0,0116525424",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"22,52",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2661,49,2728,"0,0179618768",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"21,92","14,55"
"low bq, bad alignment, many samples",UPN2_056,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1095,25,1123,"0,0222617988",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"22,22","14,88"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1493,32,1530,"0,0209150327",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"22,31",14
"low bq, bad alignment, many samples",UPN2_058,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1764,47,1825,"0,0257534247",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"21,87","14,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_040,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1717,37,1763,"0,0209869541",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"19,68","14,35"
"low bq, bad alignment, many samples",UPN2_091,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1194,27,1224,"0,0220588235",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"23,59",14
"low bq, bad alignment, many samples",UPN2_094,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1198,33,1235,"0,0267206478",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"23,95",14
"low bq, bad alignment, many samples",UPN2_096,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1484,44,1531,"0,028739386",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"23,34","14,91"
"low bq, bad alignment, many samples",UPN2_097,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1720,43,1766,"0,0243488109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"23,92",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_102,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1152,24,1179,"0,0203562341",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"24,07",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_103,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1294,28,1324,"0,0211480363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"23,98",14
"low bq, bad alignment, many samples",UPN2_104,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1366,40,1408,"0,0284090909",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"23,55","14,55"
"low bq, bad alignment, many samples",UPN2_106,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2413,59,2478,"0,0238095238",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"23,49","14,34"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_107,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2307,50,2361,"0,0211774672",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"23,64",14
"low bq, bad alignment, many samples",UPN2_108,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2346,71,2419,"0,0293509715",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"23,69","14,49"
"low bq, bad alignment, many samples",UPN2_109,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1670,51,1722,"0,0296167247",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"23,66","14,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_110,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2233,49,2286,"0,0214348206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"23,86","14,27"
"low bq, bad alignment",UPN2_111,21,36164608,G,C,missense_variant(MODERATE|MISSENSE|Cgc/Ggc|p.Arg423Gly/c.1267C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1393,40,1435,"0,0278745645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,93",Deleterious,93,Tolerated,"23,89","14,77"
"low bq, bad alignment, many samples",UPN2_015,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),900,354,2859,"0,1238195173",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"17,32","14,23"
"low bq, bad alignment, many samples",UPN2_017,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),250,105,813,"0,1291512915",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"17,18","15,01"
"low bq, bad alignment, many samples",UPN2_018,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),419,169,1273,"0,1327572663",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"17,34","14,5"
"low bq, bad alignment, many samples",UPN2_019,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),438,165,1382,"0,1193921852",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"17,31","14,13"
"low bq, bad alignment, many samples",UPN2_020,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),272,133,873,"0,1523482245",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"17,76","14,88"
"low bq, bad alignment, many samples",UPN2_022,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),542,242,1727,"0,1401273885",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"17,24","14,48"
"low bq, bad alignment, many samples",UPN2_023,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),546,231,1779,"0,1298482293",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"17,72","14,08"
"low bq, bad alignment, many samples",UPN2_024,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),292,126,845,"0,149112426",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"17,16","14,35"
"low bq, bad alignment, many samples",UPN2_089,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),684,36,1003,"0,035892323",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"15,69",14
"low bq, bad alignment, many samples",UPN2_044,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),123,42,388,"0,1082474227",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"17,5","15,57"
"low bq, bad alignment, many samples",UPN2_031,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),526,217,1562,"0,1389244558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"16,94","14,15"
"low bq, bad alignment, many samples",UPN2_045,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),514,164,1822,"0,0900109769",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"19,27","14,91"
"low bq, bad alignment, many samples",UPN2_033,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),451,178,1344,"0,1324404762",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"17,53","14,45"
"low bq, bad alignment, many samples",UPN2_006,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),241,65,708,"0,0918079096",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"17,39","14,95"
"low bq, bad alignment, many samples",UPN2_050,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),481,123,1602,"0,0767790262",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"18,69","14,33"
"low bq, bad alignment, many samples",UPN2_052,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),528,138,1716,"0,0804195804",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"19,43","14,9"
"low bq, bad alignment, many samples",UPN2_009,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),627,183,1848,"0,099025974",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"16,94","14,12"
"low bq, bad alignment, many samples",UPN2_010,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),302,85,883,"0,0962627407",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"17,83","14,78"
"low bq, bad alignment, many samples",UPN2_011,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),441,132,1269,"0,1040189125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"16,94","14,3"
"low bq, bad alignment, many samples",UPN2_056,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),319,97,1070,"0,0906542056",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"19,42","14,3"
"low bq, bad alignment, many samples",UPN2_090,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),601,32,870,"0,0367816092",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"16,04",14
"low bq, bad alignment, many samples",UPN2_057,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),425,143,1460,"0,0979452055",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"19,24","14,62"
"low bq, bad alignment, many samples",UPN2_091,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),848,43,1218,"0,0353037767",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"15,94","14,42"
"low bq, bad alignment, many samples",UPN2_093,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),441,22,657,"0,0334855403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"15,9",14
"low bq, bad alignment, many samples",UPN2_094,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),842,61,1234,"0,0494327391",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"15,94","15,02"
"low bq, bad alignment, many samples",UPN2_095,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),805,36,1170,"0,0307692308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"15,92",14
"low bq, bad alignment, many samples",UPN2_096,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1051,52,1520,"0,0342105263",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"15,93","14,42"
"low bq, bad alignment, many samples",UPN2_097,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1201,67,1761,"0,0380465645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"15,88","14,27"
"low bq, bad alignment, many samples",UPN2_098,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),895,40,1309,"0,0305576776",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"15,89",14
"low bq, bad alignment, many samples",UPN2_099,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),452,36,660,"0,0545454545",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"16,1","14,61"
"low bq, bad alignment, many samples",UPN2_100,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),819,58,1220,"0,0475409836",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"15,9","14,88"
"low bq, bad alignment, many samples",UPN2_101,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),640,40,949,"0,0421496312",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"16,55","14,18"
"low bq, bad alignment, many samples",UPN2_102,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),805,47,1173,"0,0400682012",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"15,99","14,94"
"low bq, bad alignment, many samples",UPN2_103,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),884,54,1316,"0,0410334347",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"15,98","14,81"
"low bq, bad alignment, many samples",UPN2_104,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),957,59,1400,"0,0421428571",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"15,68","14,49"
"low bq, bad alignment, many samples",UPN2_105,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),616,32,900,"0,0355555556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"16,18",14
"low bq, bad alignment, many samples",UPN2_106,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1724,91,2462,"0,0369618197",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"15,93","14,64"
"low bq, bad alignment, many samples",UPN2_107,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1605,90,2344,"0,0383959044",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"16,24","14,49"
"low bq, bad alignment, many samples",UPN2_108,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1650,87,2409,"0,0361145704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"15,9","14,46"
"low bq, bad alignment, many samples",UPN2_109,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1213,60,1715,"0,0349854227",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"16,24",14
"low bq, bad alignment, many samples",UPN2_110,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1564,91,2273,"0,0400351958",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"15,76",14
"low bq, bad alignment",UPN2_111,21,36164610,T,A,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu422Val/c.1265A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),982,56,1427,"0,0392431675",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,1,Damaging,"15,92","14,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,21,36164610,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu422Gly/c.1265A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),514,22,1822,"0,0120746432",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,31",Deleterious,2,Damaging,"19,27","23,41"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_048,21,36164610,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu422Gly/c.1265A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),962,33,3165,"0,0104265403",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,31",Deleterious,2,Damaging,"17,96","25,52"
"low freq, many artifacts, many samples",UPN2_055,21,36164610,T,C,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu422Gly/c.1265A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),730,30,2645,"0,011342155",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,31",Deleterious,2,Damaging,"18,83","28,23"
"low bq, many samples, no database",UPN2_001,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),209,404,687,"0,5880640466",0,0,1,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,"0,003",Damaging,"17,65","14,26"
"low bq, bad alignment, many samples",UPN2_014,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),442,884,1569,"0,5634161887",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"17,36","14,06"
"low bq, bad alignment, many samples",UPN2_015,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),900,1597,2859,"0,5585869185",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"17,32","14,06"
"low bq, bad alignment, many samples",UPN2_016,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),338,620,1118,"0,5545617174",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"16,79","14,02"
"low bq, many samples, no database",UPN2_017,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),250,450,813,"0,5535055351",1,0,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,"0,003",Damaging,"17,18",14
"low bq, bad alignment, many samples",UPN2_018,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),419,682,1273,"0,5357423409",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"17,34","14,05"
"low bq, bad alignment, many samples",UPN2_019,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),438,763,1382,"0,5520984081",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"17,31","14,03"
"low bq, bad alignment, many samples",UPN2_020,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),272,465,873,"0,5326460481",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"17,76","14,1"
"low bq, bad alignment, many samples",UPN2_021,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),372,645,1191,"0,5415617128",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"16,42","14,06"
"low bq, bad alignment, many samples",UPN2_002,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),242,410,715,"0,5734265734",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"16,81","14,09"
"low bq, bad alignment, many samples",UPN2_003,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),54,74,142,"0,5211267606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"16,37","14,09"
"low bq, bad alignment, many samples",UPN2_022,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),542,934,1727,"0,5408222351",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"17,24","14,06"
"low bq, bad alignment, many samples",UPN2_023,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),546,994,1779,"0,5587408657",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"17,72","14,06"
"low bq, bad alignment, many samples",UPN2_024,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),292,422,845,"0,499408284",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"17,16",14
"low bq, many samples, no database",UPN2_025,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),699,1358,2410,"0,5634854772",1,0,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,"0,003",Damaging,"17,08","14,07"
"low bq, bad alignment, many samples",UPN2_026,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),539,1048,1837,"0,5704953729",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"17,58","14,04"
"low bq, many samples, no database",UPN2_004,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),47,91,153,"0,5947712418",1,0,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,"0,003",Damaging,"16,15","14,15"
"low bq, bad alignment, many samples",UPN2_027,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),563,1102,1908,"0,5775681342",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"16,78","14,02"
"low bq, bad alignment, many samples",UPN2_089,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),684,281,1003,"0,2801595214",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"15,69",14
"low bq, bad alignment, many samples",UPN2_042,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),889,1810,2976,"0,6081989247",1,0,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"19,74","14,07"
"low bq, many samples, no database",UPN2_028,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),396,787,1330,"0,5917293233",1,0,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,"0,003",Damaging,"17,59","14,06"
"low bq, bad alignment, many samples",UPN2_044,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),123,215,388,"0,5541237113",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"17,5","14,09"
"low bq, bad alignment, many samples",UPN2_029,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),395,728,1328,"0,5481927711",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"17,03","14,04"
"low bq, bad alignment, many samples",UPN2_030,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),687,1162,2131,"0,5452839043",1,0,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"17,56","14,08"
"low bq, bad alignment, many samples",UPN2_031,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),526,812,1562,"0,5198463508",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"16,94","14,05"
"low bq, bad alignment, many samples",UPN2_005,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),63,113,197,"0,5736040609",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"17,3","14,24"
"low bq, many samples, no database",UPN2_045,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),514,1122,1822,"0,6158068057",1,0,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,"0,003",Damaging,"19,27","14,14"
"low bq, many samples, no database",UPN2_032,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),191,387,659,"0,5872534143",1,0,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,"0,003",Damaging,"17,52","14,04"
"low bq, bad alignment, many samples",UPN2_033,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),451,706,1344,"0,525297619",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"17,53","14,05"
"low bq, many samples, no database",UPN2_034,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),177,344,596,"0,5771812081",1,0,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,"0,003",Damaging,"17,07",14
"low bq, bad alignment, many samples",UPN2_047,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),896,1789,2980,"0,6003355705",1,0,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"19,02","14,06"
"low bq, bad alignment, many samples",UPN2_035,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),762,1271,2357,"0,5392448027",1,0,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"17,52","14,02"
"low bq, bad alignment, many samples",UPN2_036,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),439,873,1534,"0,5691003911",1,0,0,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"16,13","14,05"
"low bq, bad alignment, many samples",UPN2_006,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),241,401,708,"0,5663841808",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"17,39","14,08"
"low bq, many samples, no database",UPN2_050,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),481,992,1602,"0,6192259675",1,0,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,"0,003",Damaging,"18,69","14,14"
"low bq, many samples, no database",UPN2_052,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),528,1034,1716,"0,6025641026",1,0,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,"0,003",Damaging,"19,43","14,1"
"low bq, many samples, no database",UPN2_054,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),408,838,1392,"0,6020114943",1,0,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,"0,003",Damaging,"18,56","14,2"
"low bq, many samples, no database",UPN2_008,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),681,1213,2109,"0,5751541015",1,0,1,0,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,"0,003",Damaging,"16,7","14,2"
"low bq, many samples, no database",UPN2_009,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),627,1028,1848,"0,5562770563",1,0,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,"0,003",Damaging,"16,94","14,16"
"low bq, bad alignment, many samples",UPN2_010,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),302,491,883,"0,5560588901",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"17,83","14,22"
"low bq, bad alignment, many samples",UPN2_011,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),441,683,1269,"0,5382190701",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"16,94","14,17"
"low bq, bad alignment, many samples",UPN2_055,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),730,1654,2645,"0,6253308129",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"18,83","14,07"
"low bq, bad alignment, many samples",UPN2_056,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),319,643,1070,"0,6009345794",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"19,42","14,2"
"low bq, bad alignment, many samples",UPN2_090,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),601,235,870,"0,2701149425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"16,04","14,06"
"low bq, many samples, no database",UPN2_057,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),425,882,1460,"0,604109589",1,0,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,"0,003",Damaging,"19,24","14,19"
"low bq, many samples, no database",UPN2_012,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),294,506,894,"0,5659955257",0,0,1,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,"0,003",Damaging,"16,76","14,25"
"low bq, bad alignment, many samples",UPN2_060,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),113,36,154,"0,2337662338",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"17,47",14
"low bq, bad alignment, many samples",UPN2_040,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),501,950,1704,"0,5575117371",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"17,01","14,08"
"low bq, bad alignment, many samples",UPN2_013,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),120,220,384,"0,5729166667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"17,2","14,23"
"low bq, bad alignment, many samples",UPN2_091,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),848,326,1218,"0,2676518883",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"15,94","14,04"
"low bq, bad alignment, many samples",UPN2_092,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),349,146,510,"0,2862745098",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"15,48",14
"low bq, bad alignment, many samples",UPN2_093,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),441,193,657,"0,2937595129",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"15,9",14
"low bq, bad alignment, many samples",UPN2_061,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),60,22,86,"0,2558139535",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"16,47",14
"low bq, bad alignment, many samples",UPN2_062,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),52,22,75,"0,2933333333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"17,75",14
"low bq, bad alignment, many samples",UPN2_063,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),90,38,134,"0,2835820896",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"17,29",14
"low bq, bad alignment, many samples",UPN2_071,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),160,62,239,"0,2594142259",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"17,1",14
"low bq, bad alignment, many samples",UPN2_072,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),149,62,223,"0,2780269058",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"17,34","14,29"
"low bq, bad alignment, many samples",UPN2_075,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),76,31,111,"0,2792792793",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"16,84","14,42"
"low bq, bad alignment, many samples",UPN2_078,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),115,38,166,"0,2289156627",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"16,84",14
"low bq, bad alignment, many samples",UPN2_080,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),138,52,193,"0,2694300518",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"17,17","14,13"
"low bq, bad alignment, many samples",UPN2_081,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),134,46,187,"0,2459893048",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"16,75",14
"low bq, bad alignment, many samples",UPN2_094,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),842,327,1234,"0,2649918963",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"15,94",14
"low bq, bad alignment, many samples",UPN2_095,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),805,324,1170,"0,2769230769",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"15,92",14
"low bq, bad alignment, many samples",UPN2_096,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1051,415,1520,"0,2730263158",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"15,93","14,07"
"low bq, bad alignment, many samples",UPN2_097,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1201,488,1761,"0,2771152754",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"15,88",14
"low bq, many samples, no database",UPN2_098,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),895,370,1309,"0,282658518",1,0,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,"0,003",Damaging,"15,89","14,02"
"low bq, bad alignment, many samples",UPN2_099,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),452,171,660,"0,2590909091",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"16,1",14
"low bq, bad alignment, many samples",UPN2_100,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),819,339,1220,"0,2778688525",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"15,9","14,04"
"low bq, bad alignment, many samples",UPN2_101,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),640,266,949,"0,2802950474",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"16,55","14,03"
"low bq, many samples, no database",UPN2_102,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),805,317,1173,"0,2702472293",1,0,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,"0,003",Damaging,"15,99","14,02"
"low bq, bad alignment, many samples",UPN2_103,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),884,375,1316,"0,2849544073",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"15,98","14,03"
"low bq, bad alignment, many samples",UPN2_104,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),957,383,1400,"0,2735714286",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"15,68","14,05"
"low bq, bad alignment, many samples",UPN2_105,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),616,252,900,"0,28",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"16,18",14
"low bq, bad alignment, many samples",UPN2_106,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1724,638,2462,"0,2591389115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"15,93",14
"low bq, bad alignment, many samples",UPN2_107,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1605,644,2344,"0,2747440273",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"16,24","14,02"
"low bq, bad alignment, many samples",UPN2_108,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1650,669,2409,"0,2777085928",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"15,9","14,01"
"low bq, bad alignment, many samples",UPN2_109,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1213,439,1715,"0,2559766764",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"16,24","14,02"
"low bq, bad alignment, many samples",UPN2_110,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1564,609,2273,"0,2679278487",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"15,76","14,02"
"low bq, bad alignment",UPN2_111,21,36164610,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu422Ala/c.1265A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),982,382,1427,"0,2676944639",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,52",Deleterious,3,Damaging,"15,92","14,04"
"low bq, bad alignment, many samples",UPN2_017,21,36164611,C,A,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu422*/c.1264G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),790,20,813,"0,024600246",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"20,53","15,1"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_018,21,36164611,C,A,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu422*/c.1264G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1248,20,1272,"0,0157232704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"20,72",14
"low bq, bad alignment, many samples",UPN2_020,21,36164611,C,A,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu422*/c.1264G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),846,26,872,"0,0298165138",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"21,58",14
"low bq, bad alignment, many samples",UPN2_024,21,36164611,C,A,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu422*/c.1264G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),821,22,845,"0,026035503",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"21,39",16
"low bq, bad alignment, many samples",UPN2_089,21,36164611,C,A,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu422*/c.1264G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),966,37,1003,"0,036889332",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"21,43","14,35"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_029,21,36164611,C,A,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu422*/c.1264G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1301,22,1327,"0,0165787491",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"20,97",15
"low bq, bad alignment, many samples",UPN2_033,21,36164611,C,A,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu422*/c.1264G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1306,31,1343,"0,0230826508",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"21,42",14
"low bq, bad alignment, many samples",UPN2_006,21,36164611,C,A,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu422*/c.1264G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),685,23,708,"0,0324858757",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"20,57",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,21,36164611,C,A,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu422*/c.1264G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1664,35,1713,"0,0204319907",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"20,53","15,63"
"low bq, bad alignment, many samples",UPN2_009,21,36164611,C,A,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu422*/c.1264G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1797,44,1845,"0,0238482385",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"21,3","14,41"
"low bq, bad alignment, many samples",UPN2_010,21,36164611,C,A,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu422*/c.1264G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),851,27,882,"0,0306122449",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"21,02","14,81"
"low bq, bad alignment, many samples",UPN2_011,21,36164611,C,A,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu422*/c.1264G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1229,36,1268,"0,0283911672",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"21,32","15,11"
"low bq, bad alignment, many samples",UPN2_090,21,36164611,C,A,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu422*/c.1264G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),846,23,870,"0,0264367816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"21,41",14
"low bq, bad alignment, many samples",UPN2_057,21,36164611,C,A,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu422*/c.1264G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1401,51,1458,"0,0349794239",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"20,42","18,16"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_058,21,36164611,C,A,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu422*/c.1264G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1694,35,1744,"0,0200688073",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"20,83","15,77"
"low bq, bad alignment, many samples",UPN2_012,21,36164611,C,A,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu422*/c.1264G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),869,22,894,"0,0246085011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"20,81","14,32"
"low bq, bad alignment, many samples",UPN2_091,21,36164611,C,A,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu422*/c.1264G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1182,32,1217,"0,026294166",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"21,56","14,41"
"low bq, bad alignment, many samples",UPN2_094,21,36164611,C,A,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu422*/c.1264G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1198,36,1234,"0,0291734198",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"21,33","15,17"
"low bq, bad alignment, many samples",UPN2_095,21,36164611,C,A,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu422*/c.1264G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1136,32,1170,"0,0273504274",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"21,24",14
"low bq, bad alignment, many samples",UPN2_096,21,36164611,C,A,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu422*/c.1264G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1465,52,1520,"0,0342105263",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"21,47",14
"low bq, bad alignment, many samples",UPN2_097,21,36164611,C,A,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu422*/c.1264G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1710,51,1761,"0,0289608177",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"21,99","14,25"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_098,21,36164611,C,A,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu422*/c.1264G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1276,28,1309,"0,0213903743",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"21,61","14,46"
"low bq, bad alignment, many samples",UPN2_100,21,36164611,C,A,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu422*/c.1264G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1181,38,1220,"0,031147541",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"21,35","14,34"
"low bq, bad alignment, many samples",UPN2_101,21,36164611,C,A,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu422*/c.1264G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),906,37,948,"0,0390295359",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"21,26",14
"low bq, bad alignment, many samples",UPN2_102,21,36164611,C,A,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu422*/c.1264G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1139,33,1172,"0,0281569966",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"21,74",14
"low bq, bad alignment, many samples",UPN2_103,21,36164611,C,A,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu422*/c.1264G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1273,41,1316,"0,0311550152",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,21,"15,07"
"low bq, bad alignment, many samples",UPN2_104,21,36164611,C,A,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu422*/c.1264G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1340,55,1400,"0,0392857143",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"21,11","14,56"
"low bq, bad alignment, many samples",UPN2_105,21,36164611,C,A,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu422*/c.1264G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),868,29,899,"0,0322580645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"21,56",14
"low bq, bad alignment, many samples",UPN2_107,21,36164611,C,A,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu422*/c.1264G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),2264,74,2341,"0,0316104229",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"21,4","14,59"
"low bq, bad alignment, many samples",UPN2_108,21,36164611,C,A,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu422*/c.1264G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),2344,61,2409,"0,0253217103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"21,45",14
"low bq, bad alignment, many samples",UPN2_109,21,36164611,C,A,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu422*/c.1264G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1644,66,1714,"0,0385064177",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"21,61","14,3"
"low bq, bad alignment, many samples",UPN2_110,21,36164611,C,A,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu422*/c.1264G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),2202,67,2270,"0,0295154185",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"21,51","14,52"
"low bq, bad alignment",UPN2_111,21,36164611,C,A,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu422*/c.1264G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1378,41,1426,"0,0287517532",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"21,47","14,61"
"Inspected, many artifacts, bad alignment!",UPN2_035,21,36164614,C,T,missense_variant(MODERATE|MISSENSE|Ggc/Agc|p.Gly421Ser/c.1261G>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),2317,32,2351,"0,0136112293",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,1",Deleterious,"0,001",Damaging,"34,42","33,53"
"low bq, many samples, no database",UPN2_001,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),206,341,550,"0,62",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"16,42","15,17"
"low bq, bad alignment, many samples",UPN2_014,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),341,971,1320,"0,7356060606",0,0,1,0,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"17,38","15,52"
"low bq, many samples, no database",UPN2_015,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),684,1673,2366,"0,7071005917",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"17,04","15,66"
"low bq, many samples, no database",UPN2_016,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),248,693,945,"0,7333333333",0,1,1,0,0,0,1,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"17,15","15,72"
"low bq, many samples, no database",UPN2_017,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),205,465,676,"0,6878698225",1,1,1,0,0,0,1,0,4,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"17,27","16,09"
"low bq, many samples, no database",UPN2_018,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),303,746,1049,"0,7111534795",0,1,1,0,0,0,1,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"17,24","15,83"
"low bq, many samples, no database",UPN2_019,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),319,837,1159,"0,7221742882",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"17,33","15,62"
"low bq, many samples, no database",UPN2_020,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),212,515,727,"0,7083906465",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"18,88","15,63"
"low bq, many samples, no database",UPN2_021,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),252,770,1025,"0,7512195122",0,1,1,0,0,0,1,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"16,82","15,65"
"low bq, many samples, no database",UPN2_002,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),199,340,541,"0,6284658041",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"15,55","15,27"
"low bq, many samples, no database",UPN2_003,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),40,77,117,"0,6581196581",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"15,32","15,16"
"low bq, many samples, no database",UPN2_022,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),407,1025,1438,"0,7127955494",0,1,1,0,0,0,1,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"17,41","15,87"
"low bq, many samples, no database",UPN2_023,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),398,1034,1442,"0,7170596394",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"17,68","15,74"
"low bq, many samples, no database",UPN2_041,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1553,2446,4021,"0,6083063914",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"17,8","16,05"
"low bq, many samples, no database",UPN2_024,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),240,462,703,"0,6571834993",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"17,45","15,49"
"low bq, many samples, no database",UPN2_025,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),578,1443,2025,"0,7125925926",0,1,1,0,0,0,1,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"17,28","15,8"
"low bq, many samples, no database",UPN2_026,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),401,1073,1477,"0,7264725796",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"17,67","15,61"
"low bq, many samples, no database",UPN2_004,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),41,77,118,"0,6525423729",1,0,1,0,0,0,1,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"16,39","15,83"
"low bq, many samples, no database",UPN2_027,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),460,1109,1579,"0,7023432552",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"16,63","15,55"
"low bq, many samples, no database",UPN2_089,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),443,500,944,"0,5296610169",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"15,15",15
"low bq, many samples, no database",UPN2_042,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),798,1305,2113,"0,6176053005",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"17,87","16,21"
"low bq, many samples, no database",UPN2_028,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),300,767,1068,"0,718164794",1,0,1,0,0,0,1,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"17,79","15,52"
"low bq, many samples, no database",UPN2_043,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),433,761,1200,"0,6341666667",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"18,03","16,21"
"low bq, many samples, no database",UPN2_044,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),103,161,267,"0,6029962547",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"17,55","15,63"
"low bq, many samples, no database",UPN2_029,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),313,770,1088,"0,7077205882",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"17,11","15,76"
"low bq, many samples, no database",UPN2_030,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),517,1279,1802,"0,7097669256",1,1,1,0,0,0,1,0,4,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"17,22","15,81"
"low bq, many samples, no database",UPN2_031,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),406,886,1293,"0,6852281516",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"17,26","15,54"
"low bq, many samples, no database",UPN2_005,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),61,97,159,"0,6100628931",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"16,87","15,57"
"low bq, many samples, no database",UPN2_045,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),518,757,1281,"0,5909445746",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"17,48","16,22"
"low bq, many samples, no database",UPN2_032,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),152,397,552,"0,7192028986",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"17,43","15,33"
"low bq, many samples, no database",UPN2_046,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),599,950,1562,"0,6081946223",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"16,85","16,17"
"low bq, many samples, no database",UPN2_033,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),350,804,1156,"0,6955017301",1,1,1,0,0,0,1,0,4,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"17,57","15,87"
"low bq, many samples, no database",UPN2_034,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),151,345,496,"0,6955645161",0,1,1,0,0,0,1,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"16,88","15,88"
"low bq, bad alignment, many samples",UPN2_047,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),886,1247,2146,"0,5810810811",0,0,0,0,0,0,1,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"17,86","16,33"
"low bq, many samples, no database",UPN2_048,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),839,1447,2301,"0,6288570187",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"17,19","15,81"
"low bq, many samples, no database",UPN2_035,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),582,1360,1949,"0,6977937404",1,0,1,0,0,0,1,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"17,54","15,72"
"low bq, many samples, no database",UPN2_036,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),333,918,1253,"0,73264166",1,0,1,0,0,0,1,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"16,27","15,64"
"low bq, many samples, no database",UPN2_006,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),210,350,565,"0,6194690265",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"15,94","15,44"
"low bq, many samples, no database",UPN2_049,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),473,866,1347,"0,6429101707",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"17,76","16,33"
"low bq, many samples, no database",UPN2_050,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),424,698,1134,"0,6155202822",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"17,04","16,22"
"low bq, many samples, no database",UPN2_037,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),675,1587,2269,"0,6994270604",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"16,89","15,67"
"low bq, many samples, no database",UPN2_051,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),691,877,1580,"0,5550632911",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"19,75","15,91"
"low bq, many samples, no database",UPN2_052,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),463,756,1223,"0,618152085",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"18,03","15,92"
"low bq, many samples, no database",UPN2_038,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),787,1757,2556,"0,6874021909",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"17,18","15,62"
"low bq, many samples, no database",UPN2_039,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),457,1207,1666,"0,7244897959",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"17,52","15,62"
"low bq, many samples, no database",UPN2_053,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),662,1058,1727,"0,6126230457",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"17,18","15,85"
"low bq, many samples, no database",UPN2_054,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),362,609,983,"0,6195320448",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"17,77","15,81"
"low bq, many samples, no database",UPN2_007,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),519,851,1376,"0,6184593023",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"15,87","15,65"
"low bq, many samples, no database",UPN2_008,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),603,1089,1702,"0,6398354877",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"15,48","15,45"
"low bq, many samples, no database",UPN2_009,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),565,942,1519,"0,6201448321",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"15,76","15,14"
"low bq, many samples, no database",UPN2_010,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),259,458,718,"0,6378830084",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"17,21","15,8"
"low bq, many samples, no database",UPN2_011,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),396,641,1043,"0,6145733461",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"15,98","15,25"
"low bq, many samples, no database",UPN2_055,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),724,1121,1858,"0,6033369214",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"17,56","15,86"
"low bq, many samples, no database",UPN2_056,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),306,458,768,"0,5963541667",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"17,64","15,8"
"low bq, many samples, no database",UPN2_090,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),395,414,810,"0,5111111111",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"16,04","15,3"
"low bq, many samples, no database",UPN2_057,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),404,643,1050,"0,6123809524",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"17,76","16,03"
"low bq, many samples, no database",UPN2_058,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),486,768,1268,"0,6056782334",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"18,27","16,56"
"low bq, many samples, no database",UPN2_012,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),281,445,731,"0,60875513",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"16,35","15,04"
"low bq, many samples, no database",UPN2_060,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),62,83,145,"0,5724137931",0,1,1,0,1,0,1,0,4,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"15,81","15,55"
"low bq, many samples, no database",UPN2_040,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),435,985,1429,"0,689293212",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"16,86","15,7"
"low bq, many samples, no database",UPN2_013,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),114,184,300,"0,6133333333",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"15,84","15,21"
"low bq, many samples, no database",UPN2_091,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),587,536,1129,"0,4747564216",0,1,1,0,0,0,1,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"15,15","15,51"
"low bq, many samples, no database",UPN2_092,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),225,243,472,"0,5148305085",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"15,16","15,25"
"low bq, many samples, no database",UPN2_093,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),274,328,602,"0,5448504983",1,1,1,0,0,0,1,0,4,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"14,95","15,65"
"low bq, many samples, no database",UPN2_061,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),43,35,78,"0,4487179487",0,0,0,0,1,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"16,88","15,4"
"low bq, bad alignment, many samples",UPN2_062,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),35,32,67,"0,4776119403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"15,86","14,22"
"low bq, many samples, no database",UPN2_063,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),57,63,120,"0,525",0,1,1,0,1,0,1,0,4,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"14,61","16,6"
"low bq, many samples, no database",UPN2_071,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),112,108,221,"0,4886877828",0,1,1,0,1,0,1,0,4,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"16,53","15,51"
"low bq, many samples, no database",UPN2_072,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),103,98,202,"0,4851485149",0,1,1,0,1,0,1,0,4,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"15,85","16,1"
"low bq, many samples, no database",UPN2_073,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),26,30,57,"0,5263157895",0,1,0,0,1,0,1,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"17,73","15,73"
"low bq, many samples, no database",UPN2_075,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),49,47,96,"0,4895833333",0,1,1,0,1,0,1,0,4,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"16,49","16,34"
"low bq, many samples, no database",UPN2_078,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),84,72,157,"0,4585987261",0,0,1,0,1,0,1,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"15,12","15,12"
"low bq, many samples, no database",UPN2_080,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),89,83,173,"0,4797687861",0,1,1,0,1,0,1,0,4,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"14,8","16,39"
"low bq, many samples, no database",UPN2_081,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),99,75,175,"0,4285714286",0,0,1,0,1,0,1,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"15,27","15,59"
"low bq, bad alignment",UPN2_084,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),26,26,52,"0,5",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"16,38","14,27"
"low bq, many samples, no database",UPN2_094,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),587,565,1153,"0,4900260191",1,0,1,0,0,0,1,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"15,59","15,24"
"low bq, many samples, no database",UPN2_095,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),544,530,1074,"0,4934823091",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"15,21","15,3"
"low bq, many samples, no database",UPN2_096,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),696,709,1410,"0,5028368794",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"15,47","15,11"
"low bq, many samples, no database",UPN2_097,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),801,835,1641,"0,5088360756",1,0,1,0,0,0,1,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"15,31","15,32"
"low bq, many samples, no database",UPN2_098,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),602,620,1225,"0,506122449",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"15,01","15,28"
"low bq, many samples, no database",UPN2_099,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),308,305,614,"0,496742671",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"15,94","15,19"
"low bq, many samples, no database",UPN2_100,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),555,567,1122,"0,5053475936",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"15,11","15,25"
"low bq, many samples, no database",UPN2_101,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),451,427,881,"0,484676504",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"15,51","14,88"
"low bq, many samples, no database",UPN2_102,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),541,538,1080,"0,4981481481",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"15,33","15,23"
"low bq, many samples, no database",UPN2_103,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),565,647,1217,"0,5316351684",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"15,28","15,11"
"low bq, many samples, no database",UPN2_104,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),622,673,1298,"0,5184899846",1,0,0,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"15,11","15,32"
"low bq, many samples, no database",UPN2_105,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),400,433,837,"0,5173237754",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"15,65","15,24"
"low bq, many samples, no database",UPN2_106,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1151,1143,2297,"0,4976055725",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"15,41","15,41"
"low bq, many samples, no database",UPN2_107,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1068,1111,2190,"0,5073059361",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"15,81","15,23"
"low bq, many samples, no database",UPN2_108,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1130,1115,2253,"0,4948956946",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"15,28","15,29"
"low bq, many samples, no database",UPN2_109,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),798,792,1594,"0,4968632371",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"15,35","15,24"
"low bq, many samples, no database",UPN2_110,21,36164619,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val419Gly/c.1256T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1049,1070,2123,"0,5040037683",0,0,1,0,0,0,1,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,81",Deleterious,0,Damaging,"15,25","15,2"
"low bq, bad alignment, many samples",UPN2_034,21,36164622,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met418Arg/c.1253T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),336,185,523,"0,3537284895",0,0,0,0,0,1,0,0,1,NO,1,NO,NO,O,NO,rs202068364,NO,"9,88E-005",NO,NO,"-4,54",Deleterious,0,Damaging,"16,63","14,42"
"low bq, bad alignment, many samples",UPN2_037,21,36164622,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met418Arg/c.1253T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1555,806,2370,"0,3400843882",0,0,0,0,0,1,0,0,1,NO,1,NO,NO,O,NO,rs202068364,NO,"9,88E-005",NO,NO,"-4,54",Deleterious,0,Damaging,"16,92","14,52"
"low bq, bad alignment, many samples",UPN2_051,21,36164622,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met418Arg/c.1253T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1280,403,1689,"0,2386027235",0,0,0,0,0,1,0,0,1,NO,1,NO,NO,O,NO,rs202068364,NO,"9,88E-005",NO,NO,"-4,54",Deleterious,0,Damaging,"21,22","14,54"
"low bq, bad alignment, many samples",UPN2_060,21,36164622,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met418Arg/c.1253T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),114,33,148,"0,222972973",0,0,0,0,1,0,0,0,1,NO,1,NO,NO,O,NO,rs202068364,NO,"9,88E-005",NO,NO,"-4,54",Deleterious,0,Damaging,"17,93","14,61"
"low bq, bad alignment, many samples",UPN2_040,21,36164622,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met418Arg/c.1253T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1020,523,1548,"0,3378552972",0,0,0,0,0,0,1,0,1,NO,1,NO,NO,O,NO,rs202068364,NO,"9,88E-005",NO,NO,"-4,54",Deleterious,0,Damaging,"17,38","14,9"
"low bq, bad alignment, many samples",UPN2_061,21,36164622,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met418Arg/c.1253T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),60,20,80,"0,25",0,0,0,0,1,0,0,0,1,NO,1,NO,NO,O,NO,rs202068364,NO,"9,88E-005",NO,NO,"-4,54",Deleterious,0,Damaging,"17,18","14,65"
"low bq, bad alignment, many samples",UPN2_063,21,36164622,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met418Arg/c.1253T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),89,31,122,"0,2540983607",0,0,0,0,1,0,0,0,1,NO,1,NO,NO,O,NO,rs202068364,NO,"9,88E-005",NO,NO,"-4,54",Deleterious,0,Damaging,"17,92","14,68"
"low bq, bad alignment, many samples",UPN2_071,21,36164622,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met418Arg/c.1253T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),182,40,223,"0,1793721973",0,0,0,0,1,0,0,0,1,NO,1,NO,NO,O,NO,rs202068364,NO,"9,88E-005",NO,NO,"-4,54",Deleterious,0,Damaging,"17,25","14,85"
"low bq, bad alignment, many samples",UPN2_078,21,36164622,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met418Arg/c.1253T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),120,39,160,"0,24375",0,0,0,0,1,0,0,0,1,NO,1,NO,NO,O,NO,rs202068364,NO,"9,88E-005",NO,NO,"-4,54",Deleterious,0,Damaging,"17,33","14,51"
"low bq, bad alignment",UPN2_080,21,36164622,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met418Arg/c.1253T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),137,45,183,"0,2459016393",0,0,0,0,1,0,0,0,1,NO,1,NO,NO,O,NO,rs202068364,NO,"9,88E-005",NO,NO,"-4,54",Deleterious,0,Damaging,"18,42","15,13"
"low bq, bad alignment, many samples",UPN2_015,21,36164623,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met418Leu/c.1252A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),4289,1823,6361,"0,2865901588",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,5,Damaging,"19,86","14,44"
"low bq, bad alignment, many samples",UPN2_022,21,36164623,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met418Leu/c.1252A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),2615,1100,3871,"0,2841642986",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,5,Damaging,"20,27","14,36"
"low bq, bad alignment, many samples",UPN2_023,21,36164623,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met418Leu/c.1252A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),2721,1124,3962,"0,2836951035",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,5,Damaging,"20,35","14,43"
"low bq, bad alignment, many samples",UPN2_026,21,36164623,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met418Leu/c.1252A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),2670,1140,3976,"0,2867203219",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,5,Damaging,"19,94","14,39"
"low bq, bad alignment, many samples",UPN2_030,21,36164623,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met418Leu/c.1252A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),3285,1365,4833,"0,2824332713",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,5,Damaging,"20,02","14,44"
"low bq, bad alignment, many samples",UPN2_033,21,36164623,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met418Leu/c.1252A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),2107,900,3111,"0,2892960463",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,5,Damaging,"20,33","14,5"
"low bq, bad alignment, many samples",UPN2_048,21,36164623,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met418Leu/c.1252A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),5980,1442,7781,"0,1853232232",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,5,Damaging,"24,97","14,55"
"low bq, bad alignment, many samples",UPN2_035,21,36164623,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met418Leu/c.1252A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),3535,1524,5247,"0,2904516867",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,5,Damaging,"20,21","14,4"
"low bq, bad alignment, many samples",UPN2_036,21,36164623,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met418Leu/c.1252A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),2263,1000,3395,"0,29455081",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,5,Damaging,"20,01","14,42"
"low bq, bad alignment, many samples",UPN2_038,21,36164623,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met418Leu/c.1252A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),4545,1961,6762,"0,2900029577",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,5,Damaging,20,"14,33"
"low bq, bad alignment, many samples",UPN2_039,21,36164623,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met418Leu/c.1252A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),3006,1281,4473,"0,2863849765",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,5,Damaging,"20,1","14,32"
"low bq, bad alignment, many samples",UPN2_007,21,36164623,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met418Leu/c.1252A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),2615,845,3640,"0,2321428571",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,5,Damaging,"21,82","14,61"
"low bq, bad alignment, many samples",UPN2_060,21,36164623,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met418Leu/c.1252A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),246,47,309,"0,1521035599",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,5,Damaging,"21,39","14,38"
"low bq, bad alignment, many samples",UPN2_063,21,36164623,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met418Leu/c.1252A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),197,32,254,"0,125984252",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,5,Damaging,"19,95","15,19"
"low bq, bad alignment, many samples",UPN2_071,21,36164623,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met418Leu/c.1252A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),342,55,442,"0,1244343891",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,5,Damaging,"20,08","14,73"
"low bq, bad alignment, many samples",UPN2_075,21,36164623,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met418Leu/c.1252A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),175,25,220,"0,1136363636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,5,Damaging,"20,82",14
"low bq, bad alignment, many samples",UPN2_078,21,36164623,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met418Leu/c.1252A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),260,46,337,"0,1364985163",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,5,Damaging,"19,78","14,98"
"low bq, bad alignment",UPN2_080,21,36164623,T,A,missense_variant(MODERATE|MISSENSE|Atg/Ttg|p.Met418Leu/c.1252A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),304,47,387,"0,1214470284",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,5,Damaging,"20,54",14
"low bq, bad alignment, many samples",UPN2_063,21,36164623,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met418Leu/c.1252A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),197,25,254,"0,0984251969",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,5,Damaging,"19,95","17,36"
"low bq, bad alignment, many samples",UPN2_071,21,36164623,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met418Leu/c.1252A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),342,44,442,"0,0995475113",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,5,Damaging,"20,08","15,7"
"low bq, bad alignment, many samples",UPN2_078,21,36164623,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met418Leu/c.1252A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),260,31,337,"0,0919881306",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,5,Damaging,"19,78","16,29"
"low bq, bad alignment",UPN2_080,21,36164623,T,G,missense_variant(MODERATE|MISSENSE|Atg/Ctg|p.Met418Leu/c.1252A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),304,34,387,"0,0878552972",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,5,Damaging,"20,54","16,21"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_020,21,36164626,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser417Pro/c.1249T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1948,27,1994,"0,0135406219",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,555,Tolerated,"24,78","15,81"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_041,21,36164626,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser417Pro/c.1249T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),13392,232,13741,"0,0168837785",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,555,Tolerated,"26,8","16,34"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_024,21,36164626,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser417Pro/c.1249T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1859,23,1897,"0,012124407",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,555,Tolerated,"24,43","15,74"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_027,21,36164626,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser417Pro/c.1249T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4199,72,4298,"0,0167519777",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,555,Tolerated,"24,51","14,68"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_089,21,36164626,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser417Pro/c.1249T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1989,35,2043,"0,0171316691",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,555,Tolerated,"24,52","16,66"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,21,36164626,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser417Pro/c.1249T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),7027,126,7195,"0,0175121612",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,555,Tolerated,"26,72","17,35"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_043,21,36164626,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser417Pro/c.1249T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3987,58,4079,"0,0142191714",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,555,Tolerated,"26,74","17,16"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,21,36164626,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser417Pro/c.1249T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4465,64,4568,"0,0140105079",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,555,Tolerated,"26,86","16,69"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,21,36164626,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser417Pro/c.1249T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5236,102,5387,"0,0189344719",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,555,Tolerated,"26,72","17,46"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_034,21,36164626,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser417Pro/c.1249T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1267,28,1299,"0,0215550423",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,555,Tolerated,"24,66","15,25"
"low bq, bad alignment, many samples",UPN2_006,21,36164626,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser417Pro/c.1249T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1486,35,1529,"0,0228907783",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,555,Tolerated,"24,09","17,29"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,21,36164626,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser417Pro/c.1249T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4460,83,4593,"0,0180709776",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,555,Tolerated,"26,66","17,08"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,21,36164626,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser417Pro/c.1249T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3734,66,3849,"0,017147311",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,555,Tolerated,"26,79","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_051,21,36164626,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser417Pro/c.1249T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4988,78,5110,"0,0152641879",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,555,Tolerated,"27,15","15,33"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,21,36164626,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser417Pro/c.1249T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4135,52,4220,"0,0123222749",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,555,Tolerated,"26,79","17,23"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_038,21,36164626,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser417Pro/c.1249T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6678,110,6841,"0,0160795205",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,555,Tolerated,"24,49","16,37"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,21,36164626,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser417Pro/c.1249T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3281,65,3379,"0,0192364605",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,555,Tolerated,"26,81","18,66"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,21,36164626,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser417Pro/c.1249T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6256,105,6399,"0,0164088139",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,555,Tolerated,"26,81","17,24"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,21,36164626,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser417Pro/c.1249T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2600,33,2653,"0,0124387486",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,555,Tolerated,"26,79","20,03"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_090,21,36164626,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser417Pro/c.1249T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1707,33,1749,"0,0188679245",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,555,Tolerated,"24,79","18,97"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_058,21,36164626,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser417Pro/c.1249T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4301,70,4411,"0,0158694174",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,555,Tolerated,"26,83","17,71"
"low bq, bad alignment, many samples",UPN2_013,21,36164626,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser417Pro/c.1249T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),792,22,822,"0,0267639903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,555,Tolerated,"24,71","14,82"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_091,21,36164626,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser417Pro/c.1249T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2406,31,2452,"0,0126427406",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,555,Tolerated,"24,76","15,87"
"low bq, bad alignment, many samples",UPN2_092,21,36164626,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser417Pro/c.1249T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1001,23,1031,"0,0223084384",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,555,Tolerated,"24,55","14,96"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_093,21,36164626,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser417Pro/c.1249T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1303,25,1334,"0,0187406297",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,555,Tolerated,"24,85","16,44"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_094,21,36164626,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser417Pro/c.1249T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2437,40,2492,"0,0160513644",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,555,Tolerated,"24,6","15,18"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_095,21,36164626,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser417Pro/c.1249T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2303,39,2362,"0,016511431",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,555,Tolerated,"24,68","17,13"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_096,21,36164626,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser417Pro/c.1249T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3010,52,3086,"0,0168502916",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,555,Tolerated,"24,72","17,87"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_097,21,36164626,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser417Pro/c.1249T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3480,45,3553,"0,0126653532",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,555,Tolerated,"24,66","16,18"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_100,21,36164626,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser417Pro/c.1249T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2405,36,2466,"0,0145985401",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,555,Tolerated,"24,91",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_101,21,36164626,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser417Pro/c.1249T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1855,31,1904,"0,0162815126",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,555,Tolerated,"24,95",16
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_102,21,36164626,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser417Pro/c.1249T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2290,39,2347,"0,0166169578",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,555,Tolerated,"24,67","17,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_103,21,36164626,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser417Pro/c.1249T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2586,35,2647,"0,0132225161",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,555,Tolerated,"24,57","14,51"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_104,21,36164626,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser417Pro/c.1249T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2748,40,2804,"0,0142653352",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,555,Tolerated,"24,56","16,25"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_105,21,36164626,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser417Pro/c.1249T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1775,26,1813,"0,0143408715",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,555,Tolerated,"24,67","14,5"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_106,21,36164626,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser417Pro/c.1249T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4883,71,4983,"0,0142484447",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,555,Tolerated,"24,67","15,82"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_107,21,36164626,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser417Pro/c.1249T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4664,70,4755,"0,014721346",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,555,Tolerated,"24,77","16,06"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_108,21,36164626,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser417Pro/c.1249T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4751,75,4862,"0,0154257507",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,555,Tolerated,"24,58","16,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_109,21,36164626,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser417Pro/c.1249T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3420,45,3484,"0,0129161883",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,555,Tolerated,"24,7","16,62"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_110,21,36164626,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser417Pro/c.1249T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4452,91,4576,"0,0198863636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,555,Tolerated,"24,67","17,88"
"low bq, bad alignment, low freq, many artifacts",UPN2_111,21,36164626,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser417Pro/c.1249T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2797,50,2865,"0,017452007",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,94",Neutral,555,Tolerated,"24,77","20,8"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_001,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1374,20,1466,"0,0136425648",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"25,14",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_019,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2947,35,3097,"0,0113012593",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"24,67","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_041,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),13207,148,13739,"0,0107722542",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"27,2","14,39"
"low bq, bad alignment, many samples",UPN2_089,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1919,82,2042,"0,0401567091",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"25,1","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_042,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6910,83,7191,"0,0115422055",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"27,21","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_043,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3929,48,4080,"0,0117647059",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"27,32",14
"low bq, low freq, many artifacts, many samples",UPN2_045,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4372,58,4567,"0,0126998029",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"27,45","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_047,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),7091,90,7399,"0,0121638059",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"27,36","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_048,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),7517,81,7815,"0,0103646833",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"27,18","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_050,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3677,44,3846,"0,0114404576",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"27,36",14
"low bq, low freq, many artifacts, many samples",UPN2_052,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4054,51,4220,"0,0120853081",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"27,21",14
"low bq, low freq, many artifacts, many samples",UPN2_054,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3211,47,3378,"0,0139135583",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"27,34","14,47"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_009,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3811,46,4022,"0,011437096",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"24,63","14,15"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_010,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1798,27,1916,"0,014091858",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"24,98",14
"low bq, low freq, many artifacts, many samples",UPN2_055,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6139,66,6400,"0,0103125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"27,36",14
"low bq, low freq, many artifacts, many samples",UPN2_056,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2554,30,2652,"0,0113122172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"27,24","14,6"
"low bq, bad alignment, many samples",UPN2_090,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1656,73,1749,"0,0417381361",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"25,06",14
"low bq, low freq, many artifacts, many samples",UPN2_058,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4257,47,4412,"0,0106527652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"27,23","14,28"
"low bq, bad alignment, many samples",UPN2_060,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),279,25,315,"0,0793650794",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"24,18",14
"low bq, bad alignment, many samples",UPN2_091,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2319,96,2450,"0,0391836735",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"25,1","14,42"
"low bq, bad alignment, many samples",UPN2_092,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),966,41,1030,"0,0398058252",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"25,05","14,32"
"low bq, bad alignment, many samples",UPN2_093,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1240,68,1334,"0,0509745127",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"25,35",14
"low bq, bad alignment, many samples",UPN2_071,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),423,27,470,"0,0574468085",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"24,03",14
"low bq, bad alignment, many samples",UPN2_072,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),404,34,447,"0,0760626398",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"23,89",14
"low bq, bad alignment, many samples",UPN2_075,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),196,21,220,"0,0954545455",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"25,05",14
"low bq, bad alignment, many samples",UPN2_078,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),306,22,336,"0,0654761905",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"22,67","14,32"
"low bq, bad alignment, many samples",UPN2_080,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),353,20,386,"0,0518134715",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"23,01",14
"low bq, bad alignment, many samples",UPN2_081,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),348,25,381,"0,0656167979",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"23,66",14
"low bq, bad alignment, many samples",UPN2_094,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2340,83,2490,"0,0333333333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"25,23",14
"low bq, bad alignment, many samples",UPN2_095,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2213,107,2360,"0,0453389831",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"25,27","14,12"
"low bq, bad alignment, many samples",UPN2_096,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2902,132,3085,"0,0427876823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"25,26","14,36"
"low bq, bad alignment, many samples",UPN2_097,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3342,144,3550,"0,0405633803",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"25,19","14,12"
"low bq, bad alignment, many samples",UPN2_098,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2455,121,2628,"0,046042618",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"25,15",14
"low bq, bad alignment, many samples",UPN2_099,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1242,51,1329,"0,0383747178",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"25,56",14
"low bq, bad alignment, many samples",UPN2_100,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2342,85,2465,"0,0344827586",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"25,1","14,47"
"low bq, bad alignment, many samples",UPN2_101,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1795,79,1904,"0,0414915966",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"25,37",14
"low bq, bad alignment, many samples",UPN2_102,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2207,83,2345,"0,0353944563",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"25,19","14,08"
"low bq, bad alignment, many samples",UPN2_103,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2471,123,2643,"0,046538025",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"25,07","14,5"
"low bq, bad alignment, many samples",UPN2_104,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2639,109,2802,"0,0389007852",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"25,23",14
"low bq, bad alignment, many samples",UPN2_105,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1701,77,1812,"0,0424944812",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"25,05","14,17"
"low bq, bad alignment, many samples",UPN2_106,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4706,196,4976,"0,0393890675",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"25,19",14
"low bq, bad alignment, many samples",UPN2_107,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4449,213,4749,"0,0448515477",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"25,23","14,06"
"low bq, bad alignment, many samples",UPN2_108,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4579,188,4859,"0,0386910887",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"25,08","14,07"
"low bq, bad alignment, many samples",UPN2_109,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3283,142,3482,"0,0407811603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"25,16",14
"low bq, bad alignment, many samples",UPN2_110,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4278,200,4576,"0,0437062937",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"25,27",14
"low bq, bad alignment",UPN2_111,21,36164628,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe416Cys/c.1247T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2688,125,2864,"0,0436452514",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,03",Deleterious,0,Damaging,"25,18",14
"low bq, bad alignment, many samples",UPN2_001,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1374,68,1466,"0,0463847203",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"25,14","17,18"
"low bq, bad alignment, many samples",UPN2_014,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3429,105,3569,"0,0294200056",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"24,71","15,31"
"low bq, bad alignment, many samples",UPN2_015,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6158,190,6417,"0,0296088515",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"24,67","16,19"
"low bq, bad alignment, many samples",UPN2_016,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2485,73,2581,"0,028283611",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"24,88","14,79"
"low bq, bad alignment, many samples",UPN2_017,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1775,54,1845,"0,0292682927",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"24,7","15,8"
"low bq, bad alignment, many samples",UPN2_018,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2816,78,2918,"0,0267306374",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"24,72","14,79"
"low bq, bad alignment, many samples",UPN2_019,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2947,105,3097,"0,0339037778",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"24,67","15,18"
"low bq, bad alignment, many samples",UPN2_020,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1930,49,1994,"0,0245737212",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"24,96","15,08"
"low bq, bad alignment, many samples",UPN2_021,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2648,90,2764,"0,0325615051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"24,54","14,4"
"low bq, bad alignment, many samples",UPN2_002,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1438,65,1522,"0,0427069645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"25,11","15,85"
"low bq, bad alignment, many samples",UPN2_022,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3767,101,3908,"0,0258444217",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"24,8","15,32"
"low bq, bad alignment, many samples",UPN2_023,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3812,143,3989,"0,0358485836",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"25,01","16,38"
"low bq, many samples",UPN2_041,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),13207,340,13739,"0,0247470704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"27,2","16,05"
"low bq, bad alignment, many samples",UPN2_024,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1823,56,1897,"0,0295202952",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"24,55","15,43"
"low bq, bad alignment, many samples",UPN2_025,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5228,166,5450,"0,0304587156",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"24,91","15,45"
"low bq, bad alignment, many samples",UPN2_026,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3874,118,4035,"0,029244114",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"24,68","14,64"
"low bq, bad alignment, many samples",UPN2_027,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4127,128,4299,"0,0297743661",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"24,66","14,97"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_089,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1919,38,2042,"0,0186092067",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"25,1","16,21"
"low bq, many samples",UPN2_042,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6910,177,7191,"0,024614101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"27,21","17,1"
"low bq, bad alignment, many samples",UPN2_028,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2829,89,2944,"0,0302309783",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"24,71","15,55"
"low bq, low freq, many artifacts, many samples",UPN2_043,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3929,88,4080,"0,0215686275",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"27,32","15,62"
"low bq, low freq, many artifacts, many samples",UPN2_044,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),949,20,986,"0,0202839757",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"27,34",14
"low bq, bad alignment, many samples",UPN2_029,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2879,93,3006,"0,0309381238",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"24,91","14,86"
"low bq, bad alignment, many samples",UPN2_030,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4706,149,4898,"0,0304205798",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"24,71","15,22"
"low bq, bad alignment, many samples",UPN2_031,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3426,116,3581,"0,0323931863",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"24,97","17,27"
"low bq, many samples",UPN2_045,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4372,124,4567,"0,0271513028",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"27,45","16,94"
"low bq, bad alignment, many samples",UPN2_032,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1438,44,1497,"0,0293921176",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"24,75","17,02"
"low bq, many samples",UPN2_046,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5161,150,5384,"0,0278603269",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"27,15","16,05"
"low bq, bad alignment, many samples",UPN2_033,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3033,81,3137,"0,0258208479",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"24,8","16,19"
"low bq, bad alignment, many samples",UPN2_034,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1238,44,1299,"0,0338722094",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"24,53","15,5"
"low bq, many samples",UPN2_047,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),7091,191,7399,"0,0258142992",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"27,36","15,87"
"low bq, many samples",UPN2_048,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),7517,190,7815,"0,0243122201",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"27,18","15,75"
"low bq, bad alignment, many samples",UPN2_035,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5079,158,5289,"0,029873322",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"24,76","16,75"
"low bq, bad alignment, many samples",UPN2_036,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3311,102,3441,"0,0296425458",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"24,72","15,99"
"low bq, bad alignment, many samples",UPN2_006,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1436,75,1526,"0,0491480996",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"25,04","15,07"
"low bq, many samples",UPN2_049,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4427,123,4594,"0,0267740531",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"27,19","15,75"
"low bq, many samples",UPN2_050,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3677,108,3846,"0,0280811232",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"27,36","15,55"
"low bq, bad alignment, many samples",UPN2_037,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5999,202,6258,"0,0322786833",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"24,55","15,42"
"low bq, many samples",UPN2_051,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4932,115,5110,"0,0225048924",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"27,3","16,34"
"low bq, many samples",UPN2_052,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4054,103,4220,"0,0244075829",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"27,21","15,17"
"low bq, bad alignment, many samples",UPN2_038,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6546,218,6839,"0,0318760053",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"24,66","15,77"
"low bq, bad alignment, many samples",UPN2_039,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4360,150,4548,"0,0329815303",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"24,7","16,4"
"low bq, many samples",UPN2_053,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5829,173,6076,"0,0284726794",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"27,27","15,4"
"low bq, many samples",UPN2_054,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3211,108,3378,"0,0319715808",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"27,34","15,88"
"low bq, bad alignment, many samples",UPN2_007,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3470,162,3665,"0,04420191",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"24,89","15,91"
"low bq, bad alignment, many samples",UPN2_008,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4378,166,4591,"0,0361576998",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"24,63","14,45"
"low bq, bad alignment, many samples",UPN2_009,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3811,150,4022,"0,0372948782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"24,63","15,35"
"low bq, bad alignment, many samples",UPN2_010,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1798,86,1916,"0,0448851775",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"24,98","15,3"
"low bq, bad alignment, many samples",UPN2_011,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2620,89,2735,"0,0325411335",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"24,59","14,99"
"low bq, many samples",UPN2_055,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6139,178,6400,"0,0278125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"27,36","16,41"
"low bq, many samples",UPN2_056,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2554,63,2652,"0,0237556561",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"27,24","15,3"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_090,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1656,20,1749,"0,0114351058",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"25,06","14,35"
"low bq, many samples",UPN2_057,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3448,113,3600,"0,0313888889",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"27,32","16,54"
"low bq, many samples",UPN2_058,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4257,101,4412,"0,0228921124",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"27,23","16,93"
"low bq, bad alignment, many samples",UPN2_012,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1839,57,1919,"0,0297029703",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"24,84","14,77"
"low bq, bad alignment, many samples",UPN2_040,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3702,112,3857,"0,0290381125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"24,69","15,23"
"low bq, bad alignment, many samples",UPN2_013,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),792,22,822,"0,0267639903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"25,18",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_091,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2319,33,2450,"0,0134693878",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"25,1","18,15"
"low bq, bad alignment, many samples",UPN2_092,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),966,23,1030,"0,0223300971",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"25,05","17,65"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_093,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1240,25,1334,"0,0187406297",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"25,35","15,4"
"low bq, bad alignment, many samples",UPN2_094,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2340,60,2490,"0,0240963855",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"25,23","19,73"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_095,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2213,37,2360,"0,0156779661",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"25,27","16,27"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_096,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2902,47,3085,"0,0152350081",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"25,26","16,91"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_097,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3342,62,3550,"0,0174647887",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"25,19","15,52"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_098,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2455,48,2628,"0,0182648402",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"25,15","16,58"
"low bq, bad alignment, many samples",UPN2_099,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1242,34,1329,"0,0255831452",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"25,56","16,59"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_100,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2342,36,2465,"0,0146044625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"25,1","16,94"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_101,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1795,29,1904,"0,0152310924",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"25,37","17,52"
"low bq, bad alignment, many samples",UPN2_102,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2207,52,2345,"0,0221748401",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"25,19","15,02"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_103,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2471,43,2643,"0,0162693908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"25,07","18,51"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_104,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2639,52,2802,"0,0185581727",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"25,23","16,12"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_105,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1701,32,1812,"0,0176600442",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"25,05","15,12"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_106,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4706,69,4976,"0,0138665595",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"25,19","14,64"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_107,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4449,82,4749,"0,017266793",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"25,23","14,71"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_108,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4579,86,4859,"0,017699115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"25,08","16,12"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_109,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3283,55,3482,"0,0157955198",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"25,16","16,91"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_110,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4278,91,4576,"0,0198863636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"25,27","15,6"
"low bq, bad alignment, low freq, many artifacts",UPN2_111,21,36164628,A,G,missense_variant(MODERATE|MISSENSE|tTc/tCc|p.Phe416Ser/c.1247T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2688,50,2864,"0,0174581006",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,89",Deleterious,0,Damaging,"25,18","15,68"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_015,21,36164629,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe416Val/c.1246T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6306,67,6416,"0,0104426434",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,22",Deleterious,0,Damaging,"21,76","15,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_028,21,36164629,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe416Val/c.1246T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2882,33,2943,"0,0112130479",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,22",Deleterious,0,Damaging,"21,89",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_031,21,36164629,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe416Val/c.1246T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3524,37,3581,"0,0103323094",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,22",Deleterious,0,Damaging,"22,39","15,03"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,21,36164629,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe416Val/c.1246T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4115,49,4220,"0,0116113744",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,22",Deleterious,0,Damaging,"24,6","14,51"
"low bq, bad alignment, low freq, many artifacts",UPN2_012,21,36164629,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe416Val/c.1246T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1887,20,1919,"0,0104220948",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,22",Deleterious,0,Damaging,"22,38",14
"low bq, low freq, many artifacts, many samples",UPN2_014,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),3526,37,3567,"0,0103728623",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,28,14
"low bq, low freq, many artifacts, many samples",UPN2_015,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),6305,88,6406,"0,0137371214",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"28,04",14
"low bq, low freq, many artifacts, many samples",UPN2_016,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),2529,39,2576,"0,0151397516",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"28,03","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_017,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1812,29,1842,"0,0157437568",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"27,99","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_018,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),2858,43,2911,"0,0147715562",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"28,05","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_020,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1951,35,1991,"0,017579106",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"28,57",14
"low bq, low freq, many artifacts, many samples",UPN2_021,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),2709,49,2761,"0,017747193",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"27,88",14
"low bq, low freq, many artifacts, many samples",UPN2_022,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),3835,61,3903,"0,0156290033",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,28,14
"low bq, low freq, many artifacts, many samples",UPN2_023,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),3919,50,3981,"0,0125596584",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"27,84","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_041,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),13430,196,13691,"0,014315974",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"29,03","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_024,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1860,33,1895,"0,017414248",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"27,74",14
"low bq, low freq, many artifacts, many samples",UPN2_027,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),4199,66,4284,"0,0154061625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"27,89",14
"low bq, low freq, many artifacts, many samples",UPN2_042,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),7041,94,7162,"0,0131248255",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"28,9",14
"low bq, low freq, many artifacts, many samples",UPN2_028,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),2893,34,2937,"0,0115764385",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"27,89",14
"low bq, low freq, many artifacts, many samples",UPN2_043,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),3982,63,4065,"0,015498155",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"28,78","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_029,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),2939,51,2999,"0,0170056686",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"28,09","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_030,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),4802,74,4890,"0,0151329243",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"28,03",14
"low bq, low freq, many artifacts, many samples",UPN2_031,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),3490,72,3576,"0,0201342282",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"28,18","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_045,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),4470,48,4542,"0,0105680317",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"29,02",14
"low bq, low freq, many artifacts, many samples",UPN2_032,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1471,21,1497,"0,0140280561",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"28,03",14
"low bq, low freq, many artifacts, many samples",UPN2_046,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),5258,71,5364,"0,0132363908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"28,8","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_033,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),3058,65,3130,"0,0207667732",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"28,1",14
"low bq, low freq, many artifacts, many samples",UPN2_034,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1270,22,1297,"0,0169622205",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"28,18","15,82"
"low bq, low freq, many artifacts, many samples",UPN2_047,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),7256,95,7379,"0,0128743732",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"28,94","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_048,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),7629,119,7781,"0,0152936641",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"28,73","16,04"
"low bq, low freq, many artifacts, many samples",UPN2_035,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),5191,79,5283,"0,0149536248",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"27,85",14
"low bq, low freq, many artifacts, many samples",UPN2_036,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),3366,58,3432,"0,0168997669",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"27,76",14
"low bq, low freq, many artifacts, many samples",UPN2_006,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1490,30,1524,"0,0196850394",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"28,44",14
"low bq, low freq, many artifacts, many samples",UPN2_049,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),4510,48,4576,"0,0104895105",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"28,82","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_050,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),3780,42,3833,"0,0109574746",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"28,85","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_037,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),6147,96,6255,"0,0153477218",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"27,96",14
"low bq, low freq, many artifacts, many samples",UPN2_051,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),4999,64,5095,"0,0125613346",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"29,23","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_052,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),4118,55,4201,"0,0130921209",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"29,1",14
"low bq, low freq, many artifacts, many samples",UPN2_038,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),6715,101,6828,"0,0147920328",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"27,99",14
"low bq, low freq, many artifacts, many samples",UPN2_039,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),4464,63,4536,"0,0138888889",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"27,79","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_053,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),5928,92,6053,"0,0151990748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"28,96","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_054,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),3306,41,3365,"0,0121842496",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"28,91",14
"low bq, low freq, many artifacts, many samples",UPN2_007,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),3571,73,3659,"0,0199508062",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"28,35","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_008,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),4498,68,4576,"0,0148601399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"28,34",14
"low bq, low freq, many artifacts, many samples",UPN2_009,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),3956,53,4017,"0,0131939258",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"28,43","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_010,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1870,36,1912,"0,0188284519",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"28,4",14
"low bq, low freq, many artifacts, many samples",UPN2_011,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),2654,59,2725,"0,0216513761",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"28,16","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_055,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),6231,107,6376,"0,0167816813",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"29,16","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_056,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),2603,37,2650,"0,0139622642",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"29,03",14
"inspected, many artifacts",UPN2_090,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1716,27,1747,"0,0154550658",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"28,03","22,04"
"low bq, low freq, many artifacts, many samples",UPN2_057,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),3516,52,3586,"0,0145008366",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"28,87","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_058,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),4303,71,4391,"0,0161694375",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"28,71",14
"low bq, many samples",UPN2_012,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1862,43,1912,"0,0224895397",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"28,49","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_040,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),3788,49,3849,"0,0127305794",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"27,8",14
"low bq, low freq, many artifacts, many samples",UPN2_094,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),2453,25,2489,"0,0100441945",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"27,94",17
"low bq, low freq, many artifacts",UPN2_096,21,36164630,C,A,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln415His/c.1245G>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),3041,36,3084,"0,0116731518",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,84",Deleterious,0,Damaging,"28,17","15,11"
"low bq, many samples",UPN2_003,21,36164631,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln415Leu/c.1244A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),247,50,322,"0,1552795031",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,41",Deleterious,1,Damaging,"29,03","14,8"
"low bq, many samples",UPN2_004,21,36164631,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln415Leu/c.1244A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),253,40,321,"0,1246105919",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,41",Deleterious,1,Damaging,"27,89",14
"low bq, many samples",UPN2_005,21,36164631,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln415Leu/c.1244A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),324,51,396,"0,1287878788",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,41",Deleterious,1,Damaging,"28,6","14,25"
"low bq, bad alignment, many samples",UPN2_060,21,36164631,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln415Leu/c.1244A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),260,25,313,"0,0798722045",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,41",Deleterious,1,Damaging,"26,18",14
"low bq, bad alignment, many samples",UPN2_063,21,36164631,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln415Leu/c.1244A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),217,23,265,"0,0867924528",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,41",Deleterious,1,Damaging,"25,37","15,35"
"low bq, bad alignment, many samples",UPN2_071,21,36164631,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln415Leu/c.1244A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),380,41,466,"0,0879828326",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,41",Deleterious,1,Damaging,"26,01","14,17"
"low bq, bad alignment, many samples",UPN2_072,21,36164631,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln415Leu/c.1244A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),370,38,446,"0,0852017937",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,41",Deleterious,1,Damaging,"26,17",14
"low bq, bad alignment, many samples",UPN2_078,21,36164631,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln415Leu/c.1244A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),270,31,334,"0,0928143713",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,41",Deleterious,1,Damaging,"25,03",14
"low bq, bad alignment, many samples",UPN2_080,21,36164631,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln415Leu/c.1244A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),315,27,385,"0,0701298701",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,41",Deleterious,1,Damaging,"25,63","14,96"
"low bq, bad alignment",UPN2_081,21,36164631,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln415Leu/c.1244A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),317,35,382,"0,0916230366",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,41",Deleterious,1,Damaging,"25,77","14,89"
"low bq, many samples",UPN2_003,21,36164631,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln415Pro/c.1244A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),247,25,322,"0,0776397516",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,62",Deleterious,6,Damaging,"29,03",14
"low bq, many samples",UPN2_004,21,36164631,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln415Pro/c.1244A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),253,28,321,"0,0872274143",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,62",Deleterious,6,Damaging,"27,89",14
"low bq, many samples",UPN2_005,21,36164631,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln415Pro/c.1244A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),324,21,396,"0,053030303",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,62",Deleterious,6,Damaging,"28,6",14
"low bq, bad alignment, many samples",UPN2_060,21,36164631,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln415Pro/c.1244A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),260,28,313,"0,089456869",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,62",Deleterious,6,Damaging,"26,18",14
"low bq, bad alignment, many samples",UPN2_063,21,36164631,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln415Pro/c.1244A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),217,24,265,"0,0905660377",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,62",Deleterious,6,Damaging,"25,37",14
"low bq, bad alignment, many samples",UPN2_071,21,36164631,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln415Pro/c.1244A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),380,45,466,"0,0965665236",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,62",Deleterious,6,Damaging,"26,01",14
"low bq, bad alignment, many samples",UPN2_072,21,36164631,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln415Pro/c.1244A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),370,38,446,"0,0852017937",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,62",Deleterious,6,Damaging,"26,17",14
"low bq, bad alignment, many samples",UPN2_075,21,36164631,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln415Pro/c.1244A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),175,24,217,"0,1105990783",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,62",Deleterious,6,Damaging,"26,17",14
"low bq, bad alignment, many samples",UPN2_078,21,36164631,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln415Pro/c.1244A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),270,32,334,"0,0958083832",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,62",Deleterious,6,Damaging,"25,03",14
"low bq, bad alignment, many samples",UPN2_080,21,36164631,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln415Pro/c.1244A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),315,43,385,"0,1116883117",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,62",Deleterious,6,Damaging,"25,63",14
"low bq, bad alignment",UPN2_081,21,36164631,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln415Pro/c.1244A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),317,27,382,"0,0706806283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,62",Deleterious,6,Damaging,"25,77",14
"low bq, bad alignment, many samples",UPN2_004,21,36164634,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr414Ser/c.1241A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),279,40,321,"0,1246105919",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,96",Deleterious,0,Damaging,"21,53","15,68"
"low bq, bad alignment, many samples",UPN2_005,21,36164634,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr414Ser/c.1241A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),339,55,395,"0,1392405063",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,96",Deleterious,0,Damaging,"22,09","14,6"
"low bq, bad alignment, many samples",UPN2_060,21,36164634,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr414Ser/c.1241A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),256,57,313,"0,1821086262",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,96",Deleterious,0,Damaging,"23,95","14,23"
"low bq, bad alignment, many samples",UPN2_063,21,36164634,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr414Ser/c.1241A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),223,40,264,"0,1515151515",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,96",Deleterious,0,Damaging,"22,93","14,32"
"low bq, bad alignment, many samples",UPN2_075,21,36164634,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr414Ser/c.1241A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),181,33,217,"0,1520737327",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,96",Deleterious,0,Damaging,"24,26","15,48"
"low bq, bad alignment, many samples",UPN2_078,21,36164634,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr414Ser/c.1241A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),279,52,333,"0,1561561562",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,96",Deleterious,0,Damaging,"22,41",14
"low bq, bad alignment, many samples",UPN2_080,21,36164634,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr414Ser/c.1241A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),331,53,384,"0,1380208333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,96",Deleterious,0,Damaging,"22,58","14,58"
"low bq, bad alignment",UPN2_081,21,36164634,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr414Ser/c.1241A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),316,67,383,"0,1749347258",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,96",Deleterious,0,Damaging,"23,27","14,49"
"low bq, bad alignment, many samples",UPN2_034,21,36164635,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr414Asn/c.1240T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),1231,50,1289,"0,0387897595",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,92",Deleterious,0,Damaging,"22,97",14
"low bq, bad alignment, many samples",UPN2_013,21,36164635,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr414Asn/c.1240T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),772,36,818,"0,04400978",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,92",Deleterious,0,Damaging,"24,54",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_093,21,36164635,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr414Asn/c.1240T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),1297,21,1324,"0,0158610272",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,92",Deleterious,0,Damaging,"25,75",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_095,21,36164635,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr414Asn/c.1240T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),2304,37,2348,"0,015758092",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,92",Deleterious,0,Damaging,"25,46",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_097,21,36164635,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr414Asn/c.1240T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),3476,44,3534,"0,012450481",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,92",Deleterious,0,Damaging,"25,67",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_098,21,36164635,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr414Asn/c.1240T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),2542,53,2611,"0,0202987361",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,92",Deleterious,0,Damaging,"25,29",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_099,21,36164635,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr414Asn/c.1240T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),1286,25,1320,"0,0189393939",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,92",Deleterious,0,Damaging,"25,74",14
"low bq, bad alignment, low freq, many artifacts",UPN2_110,21,36164635,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr414Asn/c.1240T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),4459,88,4561,"0,0192940145",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,92",Deleterious,0,Damaging,"25,47","14,2"
"low bq, bad alignment, many samples",UPN2_092,21,36164638,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser413Ala/c.1237T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),953,36,1024,"0,03515625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,1,Damaging,"25,74",14
"low bq, bad alignment, many samples",UPN2_071,21,36164638,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser413Ala/c.1237T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),427,20,465,"0,0430107527",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,1,Damaging,"24,89",14
"low bq, bad alignment, many samples",UPN2_072,21,36164638,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser413Ala/c.1237T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),405,22,446,"0,0493273543",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,1,Damaging,"24,83","14,32"
"low bq, bad alignment, many samples",UPN2_080,21,36164638,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser413Ala/c.1237T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),345,24,383,"0,0626631854",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,1,Damaging,"24,92",14
"low bq, bad alignment, many samples",UPN2_081,21,36164638,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser413Ala/c.1237T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),348,21,383,"0,0548302872",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,1,Damaging,"24,8",14
"low bq, bad alignment",UPN2_099,21,36164638,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser413Ala/c.1237T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1243,32,1318,"0,0242792109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,1,Damaging,"25,98","14,22"
"low bq, many samples",UPN2_044,21,36164638,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser413Pro/c.1237T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),925,38,975,"0,038974359",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,3,Damaging,"28,04","17,71"
"low bq, bad alignment, many samples",UPN2_092,21,36164638,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser413Pro/c.1237T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),953,32,1024,"0,03125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,3,Damaging,"25,74",14
"low bq, bad alignment, many samples",UPN2_099,21,36164638,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser413Pro/c.1237T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1243,38,1318,"0,028831563",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,77",Deleterious,3,Damaging,"25,98","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_041,21,36164640,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly412Ala/c.1235G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),13322,161,13546,"0,0118854274",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,22,Damaging,"30,21","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_042,21,36164640,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly412Ala/c.1235G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6958,90,7085,"0,0127028934",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,22,Damaging,"30,15","14,08"
"low bq, low freq, many artifacts, many samples",UPN2_043,21,36164640,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly412Ala/c.1235G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3930,59,4012,"0,0147058824",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,22,Damaging,"30,25",14
"low bq, low freq, many artifacts, many samples",UPN2_045,21,36164640,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly412Ala/c.1235G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4411,55,4490,"0,0122494432",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,22,Damaging,"30,46",14
"low bq, low freq, many artifacts, many samples",UPN2_046,21,36164640,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly412Ala/c.1235G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5204,64,5289,"0,0121005861",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,22,Damaging,"29,99","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_047,21,36164640,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly412Ala/c.1235G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),7146,93,7310,"0,0127222982",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,22,Damaging,"30,22",14
"low bq, low freq, many artifacts, many samples",UPN2_048,21,36164640,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly412Ala/c.1235G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),7519,105,7691,"0,0136523209",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,22,Damaging,"30,02","16,44"
"low bq, low freq, many artifacts, many samples",UPN2_049,21,36164640,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly412Ala/c.1235G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4440,55,4517,"0,0121762232",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,22,Damaging,"30,18",14
"low bq, low freq, many artifacts, many samples",UPN2_050,21,36164640,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly412Ala/c.1235G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3703,64,3786,"0,0169043846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,22,Damaging,"30,34",14
"low bq, low freq, many artifacts, many samples",UPN2_051,21,36164640,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly412Ala/c.1235G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4925,72,5028,"0,0143198091",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,22,Damaging,"30,53","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_052,21,36164640,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly412Ala/c.1235G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4087,52,4167,"0,0124790017",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,22,Damaging,"30,35","15,62"
"low bq, low freq, many artifacts, many samples",UPN2_053,21,36164640,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly412Ala/c.1235G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5863,86,5983,"0,0143740598",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,22,Damaging,"30,19","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_054,21,36164640,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly412Ala/c.1235G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3251,54,3321,"0,0162601626",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,22,Damaging,"30,18",14
"low bq, low freq, many artifacts, many samples",UPN2_055,21,36164640,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly412Ala/c.1235G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6179,79,6301,"0,0125376924",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,22,Damaging,"30,29",14
"low bq, low freq, many artifacts, many samples",UPN2_056,21,36164640,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly412Ala/c.1235G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2579,35,2631,"0,0133029266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,22,Damaging,"30,29",14
"low bq, low freq, many artifacts, many samples",UPN2_057,21,36164640,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly412Ala/c.1235G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3477,52,3548,"0,0146561443",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,22,Damaging,"30,19","15,04"
"low bq, low freq, many artifacts",UPN2_058,21,36164640,C,G,missense_variant(MODERATE|MISSENSE|gGc/gCc|p.Gly412Ala/c.1235G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4252,62,4336,"0,014298893",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,53",Deleterious,22,Damaging,"30,31",14
"low bq, low freq, many artifacts, many samples",UPN2_001,21,36164644,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala411Pro/c.1231G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1431,21,1453,"0,0144528562",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,4,Damaging,"29,28","16,1"
"low bq, low freq, many artifacts, many samples",UPN2_019,21,36164644,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala411Pro/c.1231G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3018,31,3053,"0,0101539469",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,4,Damaging,28,14
"low bq, low freq, many artifacts, many samples",UPN2_025,21,36164644,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala411Pro/c.1231G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5309,58,5378,"0,0107846783",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,4,Damaging,"27,96","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_042,21,36164644,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala411Pro/c.1231G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6947,83,7042,"0,0117864243",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,4,Damaging,"30,34","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_043,21,36164644,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala411Pro/c.1231G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3927,48,3983,"0,0120512177",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,4,Damaging,"30,31",14
"low bq, low freq, many artifacts, many samples",UPN2_045,21,36164644,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala411Pro/c.1231G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4413,50,4475,"0,0111731844",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,4,Damaging,"30,39","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_047,21,36164644,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala411Pro/c.1231G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),7180,75,7274,"0,0103106956",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,4,Damaging,"30,26",14
"low bq, low freq, many artifacts, many samples",UPN2_048,21,36164644,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala411Pro/c.1231G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),7558,78,7652,"0,0101934135",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,4,Damaging,"30,19",14
"low bq, low freq, many artifacts, many samples",UPN2_049,21,36164644,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala411Pro/c.1231G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4426,56,4492,"0,0124666073",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,4,Damaging,"30,11","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_051,21,36164644,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala411Pro/c.1231G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4925,64,4996,"0,0128102482",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,4,Damaging,"30,64","15,84"
"low bq, low freq, many artifacts, many samples",UPN2_053,21,36164644,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala411Pro/c.1231G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5859,68,5952,"0,0114247312",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,4,Damaging,"30,3",14
"low bq, low freq, many artifacts, many samples",UPN2_054,21,36164644,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala411Pro/c.1231G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3244,40,3294,"0,0121432908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,4,Damaging,"30,3","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_008,21,36164644,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala411Pro/c.1231G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4461,61,4528,"0,0134717314",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,4,Damaging,"29,25",14
"low bq, low freq, many artifacts, many samples",UPN2_009,21,36164644,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala411Pro/c.1231G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3912,50,3972,"0,0125881168",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,4,Damaging,"29,23","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_011,21,36164644,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala411Pro/c.1231G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2674,29,2703,"0,0107288198",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,4,Damaging,"29,26",14
"low bq, low freq, many artifacts, many samples",UPN2_056,21,36164644,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala411Pro/c.1231G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2585,28,2618,"0,0106951872",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,4,Damaging,"30,2",14
"low bq, low freq, many artifacts, many samples",UPN2_090,21,36164644,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala411Pro/c.1231G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1704,20,1729,"0,01156738",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,4,Damaging,"27,35",14
"low bq, low freq, many artifacts, many samples",UPN2_058,21,36164644,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala411Pro/c.1231G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4255,50,4311,"0,0115982371",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,4,Damaging,"30,38","16,86"
"low bq, low freq, many artifacts, many samples",UPN2_012,21,36164644,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala411Pro/c.1231G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1868,27,1900,"0,0142105263",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,4,Damaging,"29,11",14
"low bq, low freq, many artifacts, many samples",UPN2_095,21,36164644,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala411Pro/c.1231G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2307,26,2336,"0,011130137",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,4,Damaging,"27,73","15,69"
"low bq, low freq, many artifacts, many samples",UPN2_100,21,36164644,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala411Pro/c.1231G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2411,25,2441,"0,0102417042",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,4,Damaging,"27,63",14
"low bq, low freq, many artifacts, many samples",UPN2_101,21,36164644,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala411Pro/c.1231G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1863,20,1888,"0,0105932203",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,4,Damaging,"27,57",14
"low bq, low freq, many artifacts, many samples",UPN2_104,21,36164644,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala411Pro/c.1231G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2743,32,2777,"0,0115232265",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,4,Damaging,"27,57",14
"low bq, low freq, many artifacts, many samples",UPN2_106,21,36164644,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala411Pro/c.1231G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4862,54,4921,"0,0109733794",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,4,Damaging,"27,81",14
"low bq, low freq, many artifacts",UPN2_108,21,36164644,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala411Pro/c.1231G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4752,52,4810,"0,0108108108",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,41",Neutral,4,Damaging,"27,69","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_001,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1415,27,1447,"0,0186592951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"28,58",14
"low bq, bad alignment, many samples",UPN2_014,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3389,99,3497,"0,02830998",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"26,85",14
"low bq, bad alignment, many samples",UPN2_015,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6138,164,6315,"0,0259699129",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"26,98","14,21"
"low bq, many samples",UPN2_017,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1749,53,1802,"0,0294117647",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"27,39",14
"low bq, bad alignment, many samples",UPN2_019,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2955,80,3049,"0,0262381109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"26,81","14,16"
"low bq, bad alignment, many samples",UPN2_022,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3729,96,3828,"0,0250783699",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"26,82",14
"low bq, many samples",UPN2_023,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3801,98,3911,"0,02505753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"27,08",14
"low bq, low freq, many artifacts, many samples",UPN2_041,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),13172,227,13426,"0,0169074929",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"29,62","14,17"
"low bq, many samples",UPN2_024,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1806,53,1862,"0,0284640172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"27,12",14
"low bq, bad alignment, many samples",UPN2_025,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),5203,154,5361,"0,028725984",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"26,78",14
"low bq, many samples",UPN2_026,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3847,102,3956,"0,0257836198",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"27,06",14
"low bq, many samples",UPN2_027,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4074,118,4204,"0,0280685062",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"27,08","14,11"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_089,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1980,40,2021,"0,0197921821",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"26,86",14
"low bq, low freq, many artifacts, many samples",UPN2_042,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6869,127,7012,"0,0181118083",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"29,66","14,06"
"low bq, many samples",UPN2_028,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2827,66,2898,"0,0227743271",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"27,12","14,2"
"low bq, low freq, many artifacts, many samples",UPN2_043,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3895,72,3976,"0,0181086519",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"29,54",14
"low bq, many samples",UPN2_031,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3417,104,3526,"0,0294951787",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"27,14","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_045,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4395,64,4466,"0,0143304971",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"29,88",14
"low bq, bad alignment, many samples",UPN2_032,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1419,47,1469,"0,0319945541",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"26,97",14
"low bq, low freq, many artifacts, many samples",UPN2_046,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),5153,79,5241,"0,0150734593",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"29,57","14,46"
"low bq, many samples",UPN2_034,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1228,43,1274,"0,0337519623",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"27,07","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_047,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),7114,119,7244,"0,0164273882",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"29,61","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_048,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),7454,142,7628,"0,0186156266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"29,45","14,09"
"low bq, many samples",UPN2_035,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),5037,160,5199,"0,0307751491",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"27,02",14
"low bq, low freq, many artifacts, many samples",UPN2_006,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1477,25,1506,"0,0166002656",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"28,95",14
"low bq, low freq, many artifacts, many samples",UPN2_049,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4386,76,4471,"0,0169984344",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"29,73",14
"low bq, low freq, many artifacts, many samples",UPN2_050,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3686,67,3760,"0,0178191489",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"29,66","14,19"
"low bq, low freq, many artifacts, many samples",UPN2_051,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4891,81,4982,"0,0162585307",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"29,68","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_052,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4077,52,4135,"0,0125755744",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"29,69","14,35"
"low bq, bad alignment, many samples",UPN2_038,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6493,188,6688,"0,0281100478",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"26,95","14,1"
"low bq, many samples",UPN2_039,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4330,119,4455,"0,02671156",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"27,08","14,06"
"low bq, low freq, many artifacts, many samples",UPN2_053,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),5840,82,5929,"0,0138303255",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"29,63",14
"low bq, low freq, many artifacts, many samples",UPN2_054,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3221,59,3284,"0,0179658952",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"29,71","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_007,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3520,69,3611,"0,0191082803",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"28,45","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_008,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4410,85,4518,"0,0188136344",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"28,79","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_009,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3909,53,3968,"0,0133568548",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"28,72",14
"low bq, low freq, many artifacts, many samples",UPN2_010,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1866,25,1895,"0,0131926121",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"28,77",14
"low bq, many samples",UPN2_011,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2630,61,2692,"0,0226597325",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"28,84","15,3"
"low bq, low freq, many artifacts, many samples",UPN2_055,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6118,102,6250,"0,01632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"29,72","14,2"
"low bq, low freq, many artifacts, many samples",UPN2_056,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2559,43,2609,"0,0164814105",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"29,69",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_090,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1700,26,1726,"0,0150637312",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"26,91","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_057,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3460,56,3525,"0,0158865248",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"29,68","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_058,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4204,86,4299,"0,0200046522",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"29,76","14,15"
"low bq, low freq, many artifacts, many samples",UPN2_012,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1851,41,1894,"0,0216473073",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"28,66",14
"low bq, low freq, many artifacts, many samples",UPN2_091,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2371,41,2417,"0,0169631775",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"27,12",14
"low bq, low freq, many artifacts, many samples",UPN2_094,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2422,42,2472,"0,0169902913",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"27,08","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_095,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2290,38,2332,"0,0162950257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"27,04",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_096,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2995,52,3049,"0,0170547721",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"26,98","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_097,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3443,68,3517,"0,0193346602",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"27,16","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_098,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2534,54,2597,"0,0207932229",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"27,12",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_100,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2400,39,2439,"0,0159901599",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"26,9",14
"low bq, low freq, many artifacts, many samples",UPN2_101,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1861,24,1885,"0,0127320955",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"27,33","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_103,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2559,47,2611,"0,018000766",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"27,27",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_104,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2709,60,2775,"0,0216216216",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"26,87","14,22"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_106,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4812,96,4911,"0,0195479536",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"26,97","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_107,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4613,76,4695,"0,0161874334",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"27,17","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_108,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4716,81,4800,"0,016875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"27,02","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_109,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3374,62,3444,"0,0180023229",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"27,22","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_110,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4465,63,4534,"0,0138950154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"27,15","15,17"
"low bq, bad alignment, low freq, many artifacts",UPN2_111,21,36164646,G,C,missense_variant(MODERATE|MISSENSE|tCg/tGg|p.Ser410Trp/c.1229C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2779,52,2841,"0,0183034143",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,88",Deleterious,0,Damaging,"26,87",14
"low bq, many samples",UPN2_001,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1275,139,1446,"0,0961272476",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,77",14
"low bq, many samples",UPN2_014,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2969,476,3486,"0,1365461847",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,12","14,17"
"low bq, many samples",UPN2_015,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),5355,858,6286,"0,1364937957",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,09","14,14"
"low bq, many samples",UPN2_016,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2126,361,2526,"0,1429136975",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,19","14,38"
"low bq, many samples",UPN2_017,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1545,233,1794,"0,129877369",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,05","14,34"
"low bq, many samples",UPN2_018,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2454,366,2858,"0,1280615815",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,14","14,05"
"low bq, many samples",UPN2_019,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2541,463,3041,"0,1522525485",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,22","14,15"
"low bq, many samples",UPN2_021,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2295,375,2709,"0,138427464",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,01","14,1"
"low bq, many samples",UPN2_002,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1329,137,1499,"0,0913942628",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,97","14,09"
"low bq, many samples",UPN2_003,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),280,28,314,"0,0891719745",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,26","14,46"
"low bq, many samples",UPN2_022,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3208,546,3809,"0,1433447099",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,29","14,15"
"low bq, many samples",UPN2_023,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3372,498,3899,"0,1277250577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,05","14,24"
"low bq, many samples",UPN2_041,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),11941,1191,13338,"0,0892937472",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"29,9","14,47"
"low bq, many samples",UPN2_024,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1587,241,1849,"0,1303407247",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,17","14,18"
"low bq, many samples",UPN2_025,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4535,749,5346,"0,1401047512",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,05","14,16"
"low bq, many samples",UPN2_026,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3344,536,3939,"0,136075146",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,16","14,18"
"low bq, many samples",UPN2_004,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),265,41,318,"0,1289308176",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"28,22","14,54"
"low bq, many samples",UPN2_027,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3565,564,4189,"0,1346383385",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,2","14,14"
"low bq, many samples",UPN2_089,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1650,348,2013,"0,172876304",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,41","14,5"
"low bq, many samples",UPN2_042,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6221,623,6962,"0,0894857799",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"29,93","14,25"
"low bq, many samples",UPN2_028,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2458,385,2881,"0,1336341548",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,34","14,17"
"low bq, many samples",UPN2_043,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3531,361,3954,"0,0912999494",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"29,94","14,53"
"low bq, many samples",UPN2_044,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),869,82,962,"0,0852390852",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"29,84","14,32"
"low bq, many samples",UPN2_029,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2502,409,2935,"0,1393526405",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,38","14,06"
"low bq, many samples",UPN2_030,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4076,645,4776,"0,1350502513",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,24","14,12"
"low bq, many samples",UPN2_031,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3009,464,3513,"0,1320808426",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,34","14,14"
"low bq, many samples",UPN2_005,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),340,41,390,"0,1051282051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,42",14
"low bq, many samples",UPN2_045,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3999,380,4444,"0,0855085509",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"30,06","14,52"
"low bq, bad alignment, many samples",UPN2_032,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1261,192,1464,"0,131147541",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"26,94","14,04"
"low bq, many samples",UPN2_046,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4638,490,5204,"0,0941583397",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"30,04","14,36"
"low bq, many samples",UPN2_033,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2625,405,3070,"0,1319218241",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,11","14,12"
"low bq, many samples",UPN2_034,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1078,161,1267,"0,1270718232",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,03","14,16"
"low bq, many samples",UPN2_047,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6444,645,7196,"0,0896331295",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"29,91","14,42"
"low bq, many samples",UPN2_048,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6757,703,7569,"0,0928788479",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"29,91","14,25"
"low bq, many samples",UPN2_035,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4438,688,5179,"0,1328441784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,07","14,23"
"low bq, many samples",UPN2_036,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2871,472,3373,"0,1399347762",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,01","14,18"
"low bq, many samples",UPN2_006,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1317,152,1496,"0,1016042781",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,85","14,17"
"low bq, many samples",UPN2_049,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3951,413,4440,"0,093018018",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"30,08","14,14"
"low bq, many samples",UPN2_050,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3346,332,3723,"0,0891753962",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"29,87","14,52"
"low bq, many samples",UPN2_051,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4442,443,4963,"0,0892605279",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"30,02","14,42"
"low bq, many samples",UPN2_052,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3680,347,4104,"0,0845516569",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"30,04","14,27"
"low bq, many samples",UPN2_038,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),5654,916,6655,"0,1376408715",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,2","14,06"
"low bq, many samples",UPN2_039,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3804,579,4433,"0,1306113242",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,09","14,22"
"low bq, many samples",UPN2_053,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),5332,487,5895,"0,0826123834",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"29,77","14,32"
"low bq, many samples",UPN2_054,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2934,272,3261,"0,0834099969",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"29,99","14,37"
"low bq, many samples",UPN2_007,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3192,328,3590,"0,0913649025",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,35","14,05"
"low bq, many samples",UPN2_008,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3945,430,4481,"0,0959607231",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,68","14,09"
"low bq, many samples",UPN2_009,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3497,360,3955,"0,0910240202",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,35","14,14"
"low bq, many samples",UPN2_010,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1672,168,1881,"0,0893141946",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,49","14,39"
"low bq, many samples",UPN2_011,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2344,275,2676,"0,1027653214",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,56","14,14"
"low bq, many samples",UPN2_055,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),5546,550,6213,"0,0885240624",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"30,01","14,35"
"low bq, many samples",UPN2_056,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2310,225,2589,"0,0869061414",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"29,86","14,21"
"low bq, many samples",UPN2_090,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1441,265,1717,"0,1543389633",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,15","14,54"
"low bq, many samples",UPN2_057,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3129,304,3500,"0,0868571429",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"29,89","14,39"
"low bq, many samples",UPN2_058,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3857,348,4278,"0,0813464236",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"29,78","14,36"
"low bq, many samples",UPN2_012,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1639,194,1882,"0,1030818278",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,47","14,13"
"low bq, many samples",UPN2_060,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),259,51,312,"0,1634615385",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"28,01","14,51"
"low bq, many samples",UPN2_013,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),727,67,812,"0,0825123153",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,54","14,66"
"low bq, many samples",UPN2_091,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1996,399,2408,"0,1656976744",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,48","14,51"
"low bq, many samples",UPN2_092,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),830,174,1016,"0,1712598425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,39","14,25"
"low bq, many samples",UPN2_093,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1092,200,1303,"0,1534919417",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,4","14,26"
"low bq, many samples",UPN2_061,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),139,28,169,"0,1656804734",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,73","15,57"
"low bq, many samples",UPN2_062,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),118,28,146,"0,1917808219",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"28,27","14,79"
"low bq, many samples",UPN2_063,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),210,46,259,"0,1776061776",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,24","15,22"
"low bq, many samples",UPN2_071,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),369,83,457,"0,181619256",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,69","14,24"
"low bq, many samples",UPN2_072,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),362,73,439,"0,1662870159",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"28,49","14,52"
"low bq, many samples",UPN2_075,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),175,33,209,"0,1578947368",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"29,08","14,21"
"low bq, many samples",UPN2_078,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),278,49,329,"0,1489361702",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,09","14,9"
"low bq, many samples",UPN2_080,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),312,60,377,"0,1591511936",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,68","14,7"
"low bq, many samples",UPN2_081,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),321,56,380,"0,1473684211",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,32","14,25"
"low bq, many samples",UPN2_094,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2052,392,2458,"0,1594792514",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,37","14,39"
"low bq, many samples",UPN2_095,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1927,371,2320,"0,1599137931",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,57","14,47"
"low bq, many samples",UPN2_096,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2547,462,3030,"0,1524752475",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,34","14,32"
"low bq, many samples",UPN2_097,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2901,587,3510,"0,1672364672",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,33","14,45"
"low bq, many samples",UPN2_098,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2160,408,2589,"0,157589803",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,19","14,24"
"low bq, many samples",UPN2_099,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1108,183,1300,"0,1407692308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,38","14,21"
"low bq, many samples",UPN2_100,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2048,366,2425,"0,1509278351",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,36","14,4"
"low bq, many samples",UPN2_101,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1572,300,1880,"0,1595744681",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,32","14,42"
"low bq, many samples",UPN2_102,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1927,363,2306,"0,157415438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,34","14,32"
"low bq, many samples",UPN2_103,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2151,427,2598,"0,1643571978",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,48","14,34"
"low bq, many samples",UPN2_104,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2322,431,2765,"0,1558770344",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,14","14,31"
"low bq, many samples",UPN2_105,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1480,290,1782,"0,1627384961",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,55","14,11"
"low bq, many samples",UPN2_106,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4072,787,4903,"0,160513971",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,45","14,45"
"low bq, many samples",UPN2_107,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3890,751,4676,"0,1606073567",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,45","14,44"
"low bq, many samples",UPN2_108,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3991,760,4782,"0,1589293183",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,22","14,34"
"low bq, many samples",UPN2_109,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2889,518,3425,"0,1512408759",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,33","14,41"
"low bq, many samples",UPN2_110,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3766,714,4512,"0,1582446809",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,33","14,43"
low bq,UPN2_111,21,36164647,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser410Ala/c.1228T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2382,422,2826,"0,1493276716",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,82,Tolerated,"27,04","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_001,21,36164647,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser410Pro/c.1228T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1275,29,1446,"0,020055325",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,4,Damaging,"27,77","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_016,21,36164647,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser410Pro/c.1228T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2126,34,2526,"0,0134600158",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,4,Damaging,"27,19","17,88"
"low bq, low freq, many artifacts, many samples",UPN2_018,21,36164647,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser410Pro/c.1228T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2454,34,2858,"0,0118964311",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,4,Damaging,"27,14","16,24"
"low bq, low freq, many artifacts, many samples",UPN2_021,21,36164647,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser410Pro/c.1228T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2295,30,2709,"0,0110741971",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,4,Damaging,"27,01","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_002,21,36164647,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser410Pro/c.1228T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1329,29,1499,"0,0193462308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,4,Damaging,"27,97","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_022,21,36164647,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser410Pro/c.1228T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3208,51,3809,"0,013389341",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,4,Damaging,"27,29","16,1"
"low bq, low freq, many artifacts, many samples",UPN2_041,21,36164647,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser410Pro/c.1228T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),11941,185,13338,"0,0138701454",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,4,Damaging,"29,9","15,97"
"low bq, low freq, many artifacts, many samples",UPN2_026,21,36164647,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser410Pro/c.1228T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3344,50,3939,"0,0126935771",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,4,Damaging,"27,16","16,4"
"low bq, low freq, many artifacts, many samples",UPN2_027,21,36164647,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser410Pro/c.1228T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3565,51,4189,"0,0121747434",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,4,Damaging,"27,2","15,22"
"low bq, low freq, many artifacts, many samples",UPN2_042,21,36164647,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser410Pro/c.1228T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6221,101,6962,"0,0145073255",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,4,Damaging,"29,93","15,62"
"low bq, low freq, many artifacts, many samples",UPN2_028,21,36164647,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser410Pro/c.1228T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2458,32,2881,"0,0111072544",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,4,Damaging,"27,34","15,66"
"low bq, low freq, many artifacts, many samples",UPN2_043,21,36164647,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser410Pro/c.1228T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3531,52,3954,"0,0131512393",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,4,Damaging,"29,94","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_045,21,36164647,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser410Pro/c.1228T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3999,58,4444,"0,0130513051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,4,Damaging,"30,06","16,31"
"low bq, low freq, many artifacts, many samples",UPN2_046,21,36164647,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser410Pro/c.1228T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4638,62,5204,"0,0119139124",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,4,Damaging,"30,04","16,37"
"low bq, low freq, many artifacts, many samples",UPN2_033,21,36164647,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser410Pro/c.1228T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2625,31,3070,"0,0100977199",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,4,Damaging,"27,11","16,29"
"low bq, low freq, many artifacts, many samples",UPN2_034,21,36164647,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser410Pro/c.1228T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1078,25,1267,"0,0197316496",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,4,Damaging,"27,03","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_047,21,36164647,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser410Pro/c.1228T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6444,88,7196,"0,0122290161",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,4,Damaging,"29,91","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_048,21,36164647,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser410Pro/c.1228T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6757,97,7569,"0,0128154314",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,4,Damaging,"29,91","16,11"
"low bq, low freq, many artifacts, many samples",UPN2_006,21,36164647,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser410Pro/c.1228T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1317,26,1496,"0,0173796791",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,4,Damaging,"27,85","16,19"
"low bq, low freq, many artifacts, many samples",UPN2_049,21,36164647,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser410Pro/c.1228T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3951,66,4440,"0,0148648649",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,4,Damaging,"30,08","17,24"
"low bq, low freq, many artifacts, many samples",UPN2_050,21,36164647,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser410Pro/c.1228T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3346,41,3723,"0,0110126242",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,4,Damaging,"29,87","15,51"
"low bq, low freq, many artifacts, many samples",UPN2_051,21,36164647,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser410Pro/c.1228T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4442,70,4963,"0,0141043724",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,4,Damaging,"30,02","17,19"
"low bq, low freq, many artifacts, many samples",UPN2_052,21,36164647,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser410Pro/c.1228T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3680,72,4104,"0,0175438596",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,4,Damaging,"30,04","16,9"
"low bq, low freq, many artifacts, many samples",UPN2_038,21,36164647,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser410Pro/c.1228T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5654,73,6655,"0,0109691961",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,4,Damaging,"27,2","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_039,21,36164647,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser410Pro/c.1228T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3804,48,4433,"0,0108278818",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,4,Damaging,"27,09","16,77"
"low bq, low freq, many artifacts, many samples",UPN2_053,21,36164647,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser410Pro/c.1228T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5332,70,5895,"0,0118744699",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,4,Damaging,"29,77","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_054,21,36164647,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser410Pro/c.1228T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2934,53,3261,"0,0162526832",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,4,Damaging,"29,99","15,77"
"low bq, low freq, many artifacts, many samples",UPN2_007,21,36164647,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser410Pro/c.1228T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3192,59,3590,"0,0164345404",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,4,Damaging,"27,35","15,66"
"low bq, low freq, many artifacts, many samples",UPN2_008,21,36164647,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser410Pro/c.1228T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3945,97,4481,"0,0216469538",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,4,Damaging,"27,68","15,88"
"low bq, many samples",UPN2_009,21,36164647,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser410Pro/c.1228T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3497,90,3955,"0,0227560051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,4,Damaging,"27,35","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_010,21,36164647,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser410Pro/c.1228T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1672,35,1881,"0,0186071239",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,4,Damaging,"27,49","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_011,21,36164647,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser410Pro/c.1228T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2344,47,2676,"0,0175635277",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,4,Damaging,"27,56","15,51"
"low bq, low freq, many artifacts, many samples",UPN2_055,21,36164647,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser410Pro/c.1228T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5546,99,6213,"0,0159343312",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,4,Damaging,"30,01","16,42"
"low bq, low freq, many artifacts, many samples",UPN2_056,21,36164647,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser410Pro/c.1228T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2310,44,2589,"0,0169949788",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,4,Damaging,"29,86","16,84"
"low bq, low freq, many artifacts, many samples",UPN2_057,21,36164647,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser410Pro/c.1228T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3129,59,3500,"0,0168571429",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,4,Damaging,"29,89","16,34"
"low bq, low freq, many artifacts, many samples",UPN2_058,21,36164647,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser410Pro/c.1228T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3857,57,4278,"0,0133239832",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,4,Damaging,"29,78","16,58"
low bq,UPN2_012,21,36164647,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser410Pro/c.1228T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1639,43,1882,"0,022848034",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,5",Deleterious,4,Damaging,"27,47","15,53"
"inspected, many artifacts",UPN2_040,21,36164649,G,A,missense_variant(MODERATE|MISSENSE|gCc/gTc|p.Ala409Val/c.1226C>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),3720,38,3760,"0,010106383",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,"0,015",Damaging,"30,56","26,47"
"low bq, low freq, many artifacts, many samples",UPN2_001,21,36164654,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr407*/c.1221C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1394,29,1426,"0,0203366059",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,7",14
"low bq, low freq, many artifacts, many samples",UPN2_002,21,36164654,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr407*/c.1221C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1458,24,1483,"0,016183412",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,93","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_043,21,36164654,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr407*/c.1221C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3807,76,3893,"0,0195222194",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,4","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_045,21,36164654,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr407*/c.1221C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4299,75,4379,"0,017127198",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,75","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_046,21,36164654,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr407*/c.1221C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),5018,91,5120,"0,0177734375",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,51",14
"low bq, low freq, many artifacts, many samples",UPN2_006,21,36164654,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr407*/c.1221C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1455,23,1480,"0,0155405405",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,66",14
"low bq, low freq, many artifacts, many samples",UPN2_051,21,36164654,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr407*/c.1221C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4787,82,4878,"0,0168101681",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,7","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_052,21,36164654,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr407*/c.1221C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3962,79,4048,"0,0195158103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,77","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_053,21,36164654,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr407*/c.1221C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),5680,108,5797,"0,018630326",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,62","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_054,21,36164654,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr407*/c.1221C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3153,54,3210,"0,0168224299",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,62",14
"low bq, low freq, many artifacts, many samples",UPN2_008,21,36164654,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr407*/c.1221C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4326,88,4418,"0,0199185152",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,61","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_009,21,36164654,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr407*/c.1221C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3811,81,3895,"0,0207958922",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,54","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_010,21,36164654,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr407*/c.1221C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1815,39,1858,"0,0209903122",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,76",14
"low bq, low freq, many artifacts, many samples",UPN2_011,21,36164654,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr407*/c.1221C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2595,50,2645,"0,0189035917",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,55","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_055,21,36164654,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr407*/c.1221C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),5995,124,6133,"0,0202184901",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,63","14,31"
"low bq, bad alignment, many samples",UPN2_092,21,36164654,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr407*/c.1221C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),984,23,1007,"0,0228401192",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,73",14
"low bq, bad alignment, many samples",UPN2_093,21,36164654,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr407*/c.1221C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1260,33,1293,"0,0255220418",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,08","14,21"
"low bq, bad alignment, many samples",UPN2_097,21,36164654,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr407*/c.1221C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3379,94,3478,"0,027027027",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,86",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_102,21,36164654,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr407*/c.1221C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2225,49,2282,"0,0214723926",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,8","14,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_103,21,36164654,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr407*/c.1221C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2514,48,2566,"0,0187061574",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,05",14
"low bq, bad alignment, many samples",UPN2_109,21,36164654,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr407*/c.1221C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3308,76,3393,"0,0223990569",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"26,11","14,51"
"low bq, bad alignment, low freq, many artifacts",UPN2_111,21,36164654,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr407*/c.1221C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2743,58,2805,"0,0206773619",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"25,96",14
"low bq, many samples",UPN2_018,21,36164655,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr407Ser/c.1220A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2007,690,2709,"0,2547065338",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,94",Deleterious,1,Damaging,"34,06","15,24"
"low bq, many samples",UPN2_003,21,36164655,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr407Ser/c.1220A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),225,72,299,"0,2408026756",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,94",Deleterious,1,Damaging,"33,39","14,86"
"low bq, many samples",UPN2_023,21,36164655,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr407Ser/c.1220A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2748,946,3713,"0,2547805009",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,94",Deleterious,1,Damaging,"34,16","15,22"
"low bq, many samples",UPN2_041,21,36164655,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr407Ser/c.1220A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),10663,1979,12762,"0,1550697383",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,94",Deleterious,1,Damaging,"33,97","15,11"
"low bq, many samples",UPN2_026,21,36164655,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr407Ser/c.1220A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2756,950,3724,"0,2551020408",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,94",Deleterious,1,Damaging,"34,13","15,22"
"low bq, many samples",UPN2_004,21,36164655,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr407Ser/c.1220A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),225,73,301,"0,2425249169",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,94",Deleterious,1,Damaging,"33,49","15,38"
"low bq, many samples",UPN2_042,21,36164655,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr407Ser/c.1220A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5583,1014,6660,"0,1522522523",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,94",Deleterious,1,Damaging,"33,99","15,08"
"low bq, many samples",UPN2_044,21,36164655,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr407Ser/c.1220A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),784,126,917,"0,1374045802",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,94",Deleterious,1,Damaging,"34,1","14,66"
"low bq, many samples",UPN2_029,21,36164655,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr407Ser/c.1220A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2057,709,2790,"0,2541218638",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,94",Deleterious,1,Damaging,"34,32","14,92"
"low bq, many samples",UPN2_031,21,36164655,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr407Ser/c.1220A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2469,871,3355,"0,2596125186",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,94",Deleterious,1,Damaging,"34,06","15,21"
"low bq, many samples",UPN2_005,21,36164655,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr407Ser/c.1220A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),287,74,362,"0,2044198895",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,94",Deleterious,1,Damaging,"33,05","15,2"
"low bq, many samples",UPN2_045,21,36164655,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr407Ser/c.1220A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3580,630,4245,"0,148409894",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,94",Deleterious,1,Damaging,"33,96","15,57"
"low bq, many samples",UPN2_046,21,36164655,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr407Ser/c.1220A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4147,761,4949,"0,1537684381",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,94",Deleterious,1,Damaging,"34,16","15,05"
"low bq, many samples",UPN2_033,21,36164655,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr407Ser/c.1220A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2154,754,2926,"0,2576896787",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,94",Deleterious,1,Damaging,"34,03","15,31"
"low bq, many samples",UPN2_048,21,36164655,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr407Ser/c.1220A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6001,1171,7239,"0,1617626744",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,94",Deleterious,1,Damaging,"34,01","15,12"
"low bq, many samples",UPN2_049,21,36164655,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr407Ser/c.1220A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3537,633,4210,"0,1503562945",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,94",Deleterious,1,Damaging,"34,05","15,23"
"low bq, many samples",UPN2_051,21,36164655,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr407Ser/c.1220A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4010,665,4723,"0,1408003388",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,94",Deleterious,1,Damaging,"33,68","15,32"
"low bq, many samples",UPN2_052,21,36164655,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr407Ser/c.1220A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3307,591,3932,"0,1503051882",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,94",Deleterious,1,Damaging,"34,02","15,2"
"low bq, many samples",UPN2_038,21,36164655,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr407Ser/c.1220A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4615,1666,6308,"0,2641090679",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,94",Deleterious,1,Damaging,"34,15","14,98"
"low bq, many samples",UPN2_053,21,36164655,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr407Ser/c.1220A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4743,815,5608,"0,1453281027",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,94",Deleterious,1,Damaging,"34,07","15,15"
"low bq, many samples",UPN2_054,21,36164655,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr407Ser/c.1220A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2592,462,3094,"0,149321267",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,94",Deleterious,1,Damaging,"34,18","15,6"
"low bq, many samples",UPN2_055,21,36164655,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr407Ser/c.1220A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4946,894,5897,"0,1516025098",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,94",Deleterious,1,Damaging,"34,2","15,25"
"low bq, many samples",UPN2_058,21,36164655,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr407Ser/c.1220A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3429,628,4093,"0,15343269",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,94",Deleterious,1,Damaging,"34,12","15,13"
"low bq, many samples",UPN2_059,21,36164655,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr407Ser/c.1220A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),67,23,90,"0,2555555556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,94",Deleterious,1,Damaging,"29,46","15,43"
"inspected, many artifacts",UPN2_060,21,36164655,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr407Ser/c.1220A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),226,75,304,"0,2467105263",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,94",Deleterious,"0,001",Damaging,"30,25","17,49"
"low bq, many samples",UPN2_091,21,36164655,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr407Ser/c.1220A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1660,673,2341,"0,2874839812",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,94",Deleterious,1,Damaging,"31,58","14,88"
"low bq, many samples",UPN2_061,21,36164655,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr407Ser/c.1220A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),128,36,164,"0,2195121951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,94",Deleterious,1,Damaging,"30,13","15,33"
"low bq, many samples",UPN2_062,21,36164655,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr407Ser/c.1220A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),105,35,142,"0,2464788732",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,94",Deleterious,1,Damaging,"30,02","15,11"
"low bq, many samples",UPN2_063,21,36164655,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr407Ser/c.1220A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),184,65,249,"0,2610441767",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,94",Deleterious,1,Damaging,"30,1","15,43"
"low bq, many samples",UPN2_071,21,36164655,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr407Ser/c.1220A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),318,113,434,"0,2603686636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,94",Deleterious,1,Damaging,"30,26","16,56"
"low bq, many samples",UPN2_073,21,36164655,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr407Ser/c.1220A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),88,32,121,"0,2644628099",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,94",Deleterious,1,Damaging,"30,17","16,47"
"low bq, many samples",UPN2_075,21,36164655,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr407Ser/c.1220A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),160,41,202,"0,202970297",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,94",Deleterious,1,Damaging,"31,18","14,32"
"low bq, many samples",UPN2_078,21,36164655,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr407Ser/c.1220A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),230,80,311,"0,2572347267",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,94",Deleterious,1,Damaging,"29,47","15,59"
"low bq, many samples",UPN2_080,21,36164655,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr407Ser/c.1220A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),275,89,364,"0,2445054945",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,94",Deleterious,1,Damaging,"30,15","14,84"
"low bq, many samples",UPN2_081,21,36164655,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr407Ser/c.1220A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),269,89,363,"0,2451790634",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,94",Deleterious,1,Damaging,"30,31","14,58"
"low bq, many samples",UPN2_083,21,36164655,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr407Ser/c.1220A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),64,25,89,"0,2808988764",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,94",Deleterious,1,Damaging,"30,28",14
"low bq, many samples",UPN2_084,21,36164655,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr407Ser/c.1220A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),82,27,109,"0,247706422",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,94",Deleterious,1,Damaging,"30,02","14,96"
low bq,UPN2_110,21,36164655,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr407Ser/c.1220A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3016,1338,4368,"0,3063186813",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-6,94",Deleterious,1,Damaging,"31,9","14,78"
"low bq, many samples",UPN2_004,21,36164658,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr406Ser/c.1217A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),274,24,301,"0,0797342193",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,77",Deleterious,0,Damaging,"27,51","14,29"
"low bq, many samples",UPN2_005,21,36164658,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr406Ser/c.1217A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),340,22,362,"0,0607734807",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,77",Deleterious,0,Damaging,"28,15","14,59"
"low bq, bad alignment, many samples",UPN2_063,21,36164658,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr406Ser/c.1217A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),219,30,249,"0,1204819277",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,77",Deleterious,0,Damaging,"25,54","15,03"
"low bq, bad alignment, many samples",UPN2_078,21,36164658,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr406Ser/c.1217A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),281,29,311,"0,0932475884",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,77",Deleterious,0,Damaging,"26,05",14
"low bq, bad alignment",UPN2_080,21,36164658,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr406Ser/c.1217A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),326,31,363,"0,085399449",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,77",Deleterious,0,Damaging,"26,49",14
"low bq, low freq, many artifacts, many samples",UPN2_050,21,36164659,A,G,missense_variant(MODERATE|MISSENSE|Tac/Cac|p.Tyr406His/c.1216T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3452,40,3564,"0,0112233446",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,85",Deleterious,0,Damaging,"30,61","18,95"
"low bq, low freq, many artifacts, many samples",UPN2_090,21,36164659,A,G,missense_variant(MODERATE|MISSENSE|Tac/Cac|p.Tyr406His/c.1216T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1607,24,1654,"0,0145102781",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,85",Deleterious,0,Damaging,"27,12","17,12"
"low bq, low freq, many artifacts, many samples",UPN2_012,21,36164659,A,G,missense_variant(MODERATE|MISSENSE|Tac/Cac|p.Tyr406His/c.1216T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1714,20,1773,"0,0112803158",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,85",Deleterious,0,Damaging,"27,97",16
"low bq, low freq, many artifacts, many samples",UPN2_095,21,36164659,A,G,missense_variant(MODERATE|MISSENSE|Tac/Cac|p.Tyr406His/c.1216T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2174,29,2244,"0,0129233512",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,85",Deleterious,0,Damaging,"27,11","15,97"
"low freq, many artifacts, many samples",UPN2_096,21,36164659,A,G,missense_variant(MODERATE|MISSENSE|Tac/Cac|p.Tyr406His/c.1216T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2811,36,2914,"0,0123541524",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,85",Deleterious,0,Damaging,27,"17,81"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_097,21,36164659,A,G,missense_variant(MODERATE|MISSENSE|Tac/Cac|p.Tyr406His/c.1216T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3301,58,3416,"0,0169789227",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,85",Deleterious,0,Damaging,"26,83","17,97"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_098,21,36164659,A,G,missense_variant(MODERATE|MISSENSE|Tac/Cac|p.Tyr406His/c.1216T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2431,38,2515,"0,0151093439",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,85",Deleterious,0,Damaging,"26,79","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_100,21,36164659,A,G,missense_variant(MODERATE|MISSENSE|Tac/Cac|p.Tyr406His/c.1216T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2274,36,2350,"0,0153191489",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,85",Deleterious,0,Damaging,"27,06","16,89"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_101,21,36164659,A,G,missense_variant(MODERATE|MISSENSE|Tac/Cac|p.Tyr406His/c.1216T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1762,24,1828,"0,0131291028",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,85",Deleterious,0,Damaging,"26,97",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_106,21,36164659,A,G,missense_variant(MODERATE|MISSENSE|Tac/Cac|p.Tyr406His/c.1216T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4622,61,4769,"0,0127909415",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,85",Deleterious,0,Damaging,"26,88","17,77"
"low bq, low freq, many artifacts, many samples",UPN2_107,21,36164659,A,G,missense_variant(MODERATE|MISSENSE|Tac/Cac|p.Tyr406His/c.1216T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4355,69,4505,"0,0153163152",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,85",Deleterious,0,Damaging,"27,13","16,12"
"low bq, low freq, many artifacts, many samples",UPN2_109,21,36164659,A,G,missense_variant(MODERATE|MISSENSE|Tac/Cac|p.Tyr406His/c.1216T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3201,55,3317,"0,0165812481",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,85",Deleterious,0,Damaging,"27,06","16,36"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_110,21,36164659,A,G,missense_variant(MODERATE|MISSENSE|Tac/Cac|p.Tyr406His/c.1216T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4233,51,4359,"0,0116999312",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,85",Deleterious,0,Damaging,"26,76",17
"low bq, bad alignment, low freq, many artifacts",UPN2_111,21,36164659,A,G,missense_variant(MODERATE|MISSENSE|Tac/Cac|p.Tyr406His/c.1216T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2632,34,2731,"0,0124496521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,85",Deleterious,0,Damaging,"26,91","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_001,21,36164659,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr406Asn/c.1216T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),1318,29,1363,"0,0212765957",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,86",Deleterious,0,Damaging,"28,61","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_002,21,36164659,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr406Asn/c.1216T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),1378,29,1423,"0,02037948",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,86",Deleterious,0,Damaging,"28,7",14
"low bq, low freq, many artifacts, many samples",UPN2_041,21,36164659,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr406Asn/c.1216T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),12419,232,12747,"0,0182003609",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,86",Deleterious,0,Damaging,"30,57","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_042,21,36164659,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr406Asn/c.1216T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),6486,93,6649,"0,0139870657",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,86",Deleterious,0,Damaging,"30,63","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_043,21,36164659,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr406Asn/c.1216T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),3677,63,3777,"0,0166799047",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,86",Deleterious,0,Damaging,"30,46","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_045,21,36164659,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr406Asn/c.1216T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),4135,69,4241,"0,0162697477",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,86",Deleterious,0,Damaging,"30,67","15,86"
"low bq, low freq, many artifacts, many samples",UPN2_046,21,36164659,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr406Asn/c.1216T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),4823,68,4940,"0,0137651822",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,86",Deleterious,0,Damaging,"30,69","15,62"
"low bq, low freq, many artifacts, many samples",UPN2_047,21,36164659,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr406Asn/c.1216T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),6699,107,6867,"0,0155817679",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,86",Deleterious,0,Damaging,"30,55","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_048,21,36164659,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr406Asn/c.1216T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),7040,130,7227,"0,0179881002",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,86",Deleterious,0,Damaging,"30,53","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_049,21,36164659,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr406Asn/c.1216T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),4102,56,4201,"0,0133301595",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,86",Deleterious,0,Damaging,"30,72","15,8"
"low bq, low freq, many artifacts, many samples",UPN2_050,21,36164659,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr406Asn/c.1216T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),3452,64,3564,"0,0179573513",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,86",Deleterious,0,Damaging,"30,61","15,58"
"low bq, low freq, many artifacts, many samples",UPN2_051,21,36164659,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr406Asn/c.1216T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),4612,65,4718,"0,0137770242",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,86",Deleterious,0,Damaging,"30,76","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_052,21,36164659,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr406Asn/c.1216T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),3841,56,3927,"0,0142602496",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,86",Deleterious,0,Damaging,"30,63","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_053,21,36164659,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr406Asn/c.1216T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),5483,79,5604,"0,0140970735",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,86",Deleterious,0,Damaging,"30,55","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_054,21,36164659,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr406Asn/c.1216T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),3014,43,3087,"0,0139293813",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,86",Deleterious,0,Damaging,"30,77",14
"low bq, low freq, many artifacts, many samples",UPN2_055,21,36164659,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr406Asn/c.1216T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),5741,100,5892,"0,0169721656",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,86",Deleterious,0,Damaging,"30,73","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_056,21,36164659,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr406Asn/c.1216T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),2416,45,2483,"0,018123238",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,86",Deleterious,0,Damaging,"30,41","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_090,21,36164659,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr406Asn/c.1216T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),1607,22,1654,"0,0133010883",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,86",Deleterious,0,Damaging,"27,12",14
"low bq, low freq, many artifacts, many samples",UPN2_057,21,36164659,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr406Asn/c.1216T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),3251,46,3327,"0,0138262699",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,86",Deleterious,0,Damaging,"30,75",14
"low bq, low freq, many artifacts, many samples",UPN2_058,21,36164659,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr406Asn/c.1216T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),3979,84,4090,"0,0205378973",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,86",Deleterious,0,Damaging,"30,72","15,83"
"low bq, low freq, many artifacts, many samples",UPN2_012,21,36164659,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr406Asn/c.1216T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),1714,38,1773,"0,0214326001",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,86",Deleterious,0,Damaging,"27,97",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_092,21,36164659,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr406Asn/c.1216T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),942,21,980,"0,0214285714",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,86",Deleterious,0,Damaging,"26,96","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_093,21,36164659,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr406Asn/c.1216T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),1211,21,1249,"0,0168134508",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,86",Deleterious,0,Damaging,"27,09",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_094,21,36164659,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr406Asn/c.1216T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),2315,44,2382,"0,0184718724",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,86",Deleterious,0,Damaging,"26,84","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_095,21,36164659,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr406Asn/c.1216T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),2174,39,2244,"0,0173796791",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,86",Deleterious,0,Damaging,"27,11","14,33"
"low freq, many artifacts, many samples",UPN2_096,21,36164659,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr406Asn/c.1216T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),2811,64,2914,"0,0219629375",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,86",Deleterious,0,Damaging,27,"14,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_097,21,36164659,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr406Asn/c.1216T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),3301,49,3416,"0,0143442623",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,86",Deleterious,0,Damaging,"26,83","14,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_098,21,36164659,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr406Asn/c.1216T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),2431,46,2515,"0,0182902584",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,86",Deleterious,0,Damaging,"26,79","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_100,21,36164659,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr406Asn/c.1216T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),2274,40,2350,"0,0170212766",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,86",Deleterious,0,Damaging,"27,06",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_101,21,36164659,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr406Asn/c.1216T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),1762,39,1828,"0,0213347921",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,86",Deleterious,0,Damaging,"26,97","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_105,21,36164659,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr406Asn/c.1216T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),1675,27,1727,"0,0156340475",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,86",Deleterious,0,Damaging,"27,06",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_106,21,36164659,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr406Asn/c.1216T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),4622,82,4769,"0,0171943804",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,86",Deleterious,0,Damaging,"26,88",14
"low bq, low freq, many artifacts, many samples",UPN2_107,21,36164659,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr406Asn/c.1216T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),4355,79,4505,"0,017536071",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,86",Deleterious,0,Damaging,"27,13","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_109,21,36164659,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr406Asn/c.1216T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),3201,60,3317,"0,0180886343",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,86",Deleterious,0,Damaging,"27,06",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_110,21,36164659,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr406Asn/c.1216T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),4233,72,4359,"0,0165175499",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,86",Deleterious,0,Damaging,"26,76","14,49"
"low bq, bad alignment",UPN2_111,21,36164659,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr406Asn/c.1216T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),2632,61,2731,"0,0223361406",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,86",Deleterious,0,Damaging,"26,91","14,43"
"inspected, many artifacts",UPN2_049,21,36164660,C,CA,frameshift_variant(HIGH||ctg/ctTg|p.Tyr406fs/c.1214dupT|480|RUNX1|protein_coding|CODING|ENST00000437180|9|CA),4090,277,4201,"0,0659366817",0,1,0,1,1,1,0,1,5,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,47",NA
"low bq, low freq, many artifacts, many samples",UPN2_103,21,36164661,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu405Arg/c.1214T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2469,29,2511,"0,0115491836",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,75",Deleterious,0,Damaging,"27,31",14
"low bq, low freq, many artifacts, many samples",UPN2_110,21,36164661,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu405Arg/c.1214T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4285,52,4356,"0,0119375574",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,75",Deleterious,0,Damaging,"27,58","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_026,21,36164662,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu405Val/c.1213C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3646,38,3713,"0,0102343119",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,1,Damaging,"29,48",14
"low bq, low freq, many artifacts, many samples",UPN2_089,21,36164662,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu405Val/c.1213C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1882,41,1932,"0,0212215321",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,1,Damaging,"27,21",14
"low bq, low freq, many artifacts, many samples",UPN2_035,21,36164662,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu405Val/c.1213C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4835,52,4927,"0,0105540897",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,1,Damaging,"29,27",14
"low bq, low freq, many artifacts, many samples",UPN2_090,21,36164662,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu405Val/c.1213C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1620,24,1649,"0,0145542753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,1,Damaging,"27,27",14
"low bq, low freq, many artifacts, many samples",UPN2_091,21,36164662,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu405Val/c.1213C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2284,36,2332,"0,0154373928",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,1,Damaging,"27,23","14,19"
"low bq, low freq, many artifacts, many samples",UPN2_094,21,36164662,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu405Val/c.1213C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2342,32,2378,"0,0134566863",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,1,Damaging,"27,09","15,78"
"low bq, low freq, many artifacts, many samples",UPN2_095,21,36164662,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu405Val/c.1213C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2189,37,2235,"0,0165548098",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,1,Damaging,"27,64","14,19"
"low bq, low freq, many artifacts, many samples",UPN2_096,21,36164662,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu405Val/c.1213C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2845,44,2902,"0,0151619573",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,1,Damaging,"27,4","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_097,21,36164662,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu405Val/c.1213C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3343,57,3406,"0,0167351732",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,1,Damaging,"27,25",14
"low bq, low freq, many artifacts, many samples",UPN2_098,21,36164662,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu405Val/c.1213C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2466,36,2510,"0,0143426295",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,1,Damaging,"27,04","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_099,21,36164662,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu405Val/c.1213C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1236,22,1261,"0,0174464711",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,1,Damaging,"27,51",14
"low bq, low freq, many artifacts, many samples",UPN2_100,21,36164662,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu405Val/c.1213C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2297,43,2346,"0,0183290708",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,1,Damaging,"27,15",14
"low bq, low freq, many artifacts, many samples",UPN2_101,21,36164662,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu405Val/c.1213C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1794,24,1825,"0,0131506849",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,1,Damaging,"27,37",14
"low bq, low freq, many artifacts, many samples",UPN2_102,21,36164662,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu405Val/c.1213C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2164,35,2208,"0,0158514493",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,1,Damaging,"27,66",14
"low bq, low freq, many artifacts, many samples",UPN2_103,21,36164662,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu405Val/c.1213C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2461,36,2506,"0,0143655227",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,1,Damaging,"27,35",14
"low bq, low freq, many artifacts, many samples",UPN2_104,21,36164662,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu405Val/c.1213C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2610,42,2666,"0,0157539385",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,1,Damaging,"27,24","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_105,21,36164662,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu405Val/c.1213C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1687,32,1725,"0,0185507246",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,1,Damaging,"27,14",14
"low bq, low freq, many artifacts, many samples",UPN2_106,21,36164662,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu405Val/c.1213C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4646,91,4762,"0,0191096178",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,1,Damaging,"27,11",14
"low bq, low freq, many artifacts, many samples",UPN2_107,21,36164662,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu405Val/c.1213C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4413,64,4493,"0,0142443801",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,1,Damaging,"27,46",14
"low bq, low freq, many artifacts, many samples",UPN2_108,21,36164662,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu405Val/c.1213C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4527,76,4622,"0,0164430982",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,1,Damaging,"27,06",14
"low bq, low freq, many artifacts, many samples",UPN2_109,21,36164662,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu405Val/c.1213C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3247,53,3311,"0,0160072486",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,1,Damaging,"27,41",14
"low bq, low freq, many artifacts, many samples",UPN2_110,21,36164662,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu405Val/c.1213C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4250,77,4346,"0,0177174413",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,1,Damaging,"27,29",14
"low bq, low freq, many artifacts",UPN2_111,21,36164662,G,C,missense_variant(MODERATE|MISSENSE|Ctg/Gtg|p.Leu405Val/c.1213C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2670,48,2727,"0,0176017602",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,42",Neutral,1,Damaging,"27,34",14
"low bq, bad alignment, many samples",UPN2_003,21,36164664,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His404Pro/c.1211A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),257,35,293,"0,1194539249",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,"0,1",Tolerated,"19,86",14
"low bq, bad alignment, many samples",UPN2_004,21,36164664,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His404Pro/c.1211A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),260,35,296,"0,1182432432",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,"0,1",Tolerated,"20,02",14
"low bq, bad alignment, many samples",UPN2_044,21,36164664,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His404Pro/c.1211A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),856,46,910,"0,0505494505",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,"0,1",Tolerated,"22,75","14,15"
"low bq, bad alignment, many samples",UPN2_005,21,36164664,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His404Pro/c.1211A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),315,39,360,"0,1083333333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,"0,1",Tolerated,"19,69","14,56"
"low bq, bad alignment, many samples",UPN2_060,21,36164664,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His404Pro/c.1211A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),237,51,294,"0,1734693878",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,"0,1",Tolerated,"21,44","14,86"
"low bq, bad alignment, many samples",UPN2_061,21,36164664,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His404Pro/c.1211A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),136,20,160,"0,125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,"0,1",Tolerated,"18,55",15
"low bq, bad alignment, many samples",UPN2_062,21,36164664,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His404Pro/c.1211A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),113,27,141,"0,1914893617",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,"0,1",Tolerated,"19,95",14
"low bq, bad alignment, many samples",UPN2_063,21,36164664,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His404Pro/c.1211A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),200,44,247,"0,1781376518",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,"0,1",Tolerated,"20,11","15,16"
"low bq, bad alignment, many samples",UPN2_075,21,36164664,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His404Pro/c.1211A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),168,30,199,"0,1507537688",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,"0,1",Tolerated,"20,59","14,87"
"low bq, bad alignment, many samples",UPN2_078,21,36164664,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His404Pro/c.1211A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),254,54,309,"0,1747572816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,"0,1",Tolerated,"18,96","15,06"
"low bq, bad alignment, many samples",UPN2_080,21,36164664,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His404Pro/c.1211A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),304,51,360,"0,1416666667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,"0,1",Tolerated,"19,82",14
"low bq, bad alignment",UPN2_084,21,36164664,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His404Pro/c.1211A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),86,21,107,"0,1962616822",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,"0,1",Tolerated,"19,35",14
"inspected, many artifacts",UPN2_071,21,36164664,T,TG,frameshift_variant(HIGH||cac/cCac|p.His404fs/c.1210dupC|480|RUNX1|protein_coding|CODING|ENST00000437180|9|TG),346,29,415,"0,0698795181",0,1,0,1,0,1,0,1,4,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"19,87",NA
"low bq, bad alignment, many samples",UPN2_003,21,36164667,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr403Ser/c.1208A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),255,33,289,"0,1141868512",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,66",Deleterious,0,Damaging,"22,4","14,94"
"low bq, bad alignment, many samples",UPN2_004,21,36164667,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr403Ser/c.1208A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),243,48,293,"0,1638225256",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,66",Deleterious,0,Damaging,"21,95","15,67"
"low bq, bad alignment, many samples",UPN2_044,21,36164667,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr403Ser/c.1208A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),827,66,897,"0,0735785953",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,66",Deleterious,0,Damaging,"26,27","14,67"
"low bq, bad alignment, many samples",UPN2_005,21,36164667,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr403Ser/c.1208A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),311,43,354,"0,1214689266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,66",Deleterious,0,Damaging,"23,85","15,56"
"low bq, bad alignment, many samples",UPN2_039,21,36164667,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr403Ser/c.1208A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3443,609,4070,"0,1496314496",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,66",Deleterious,0,Damaging,"23,45","14,92"
"low bq, bad alignment, many samples",UPN2_008,21,36164667,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr403Ser/c.1208A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3506,564,4080,"0,1382352941",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,66",Deleterious,0,Damaging,"23,3","15,21"
"low bq, bad alignment, many samples",UPN2_009,21,36164667,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr403Ser/c.1208A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3129,484,3622,"0,1336278299",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,66",Deleterious,0,Damaging,"23,24","15,25"
"low bq, bad alignment, many samples",UPN2_061,21,36164667,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr403Ser/c.1208A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),122,37,159,"0,2327044025",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,66",Deleterious,0,Damaging,"24,48","14,49"
"low bq, bad alignment, many samples",UPN2_063,21,36164667,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr403Ser/c.1208A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),194,49,245,"0,2",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,66",Deleterious,0,Damaging,"23,64","14,55"
"low bq, bad alignment, many samples",UPN2_071,21,36164667,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr403Ser/c.1208A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),331,72,403,"0,1786600496",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,66",Deleterious,0,Damaging,"23,38","15,74"
"low bq, bad alignment, many samples",UPN2_075,21,36164667,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr403Ser/c.1208A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),165,30,197,"0,152284264",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,66",Deleterious,0,Damaging,"23,66","16,8"
"low bq, bad alignment, many samples",UPN2_080,21,36164667,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr403Ser/c.1208A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),287,71,359,"0,1977715877",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,66",Deleterious,0,Damaging,"23,39","14,97"
"low bq, bad alignment, many samples",UPN2_084,21,36164667,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr403Ser/c.1208A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),80,27,107,"0,2523364486",0,1,0,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,66",Deleterious,0,Damaging,"24,02","17,07"
"low bq, bad alignment, many samples",UPN2_095,21,36164667,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr403Ser/c.1208A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1724,479,2209,"0,2168401992",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,66",Deleterious,0,Damaging,"26,61","14,69"
"low bq, bad alignment, many samples",UPN2_096,21,36164667,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr403Ser/c.1208A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2276,574,2853,"0,201191728",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,66",Deleterious,0,Damaging,"26,78","14,86"
"low bq, bad alignment, many samples",UPN2_108,21,36164667,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr403Ser/c.1208A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3652,879,4549,"0,1932292812",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,66",Deleterious,0,Damaging,"26,52","14,63"
"low bq, bad alignment",UPN2_110,21,36164667,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr403Ser/c.1208A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3375,893,4285,"0,2084014002",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,66",Deleterious,0,Damaging,"26,67","14,79"
"low bq, many samples",UPN2_041,21,36164668,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr403Asn/c.1207T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),12117,285,12489,"0,0228200817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"29,6","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_042,21,36164668,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr403Asn/c.1207T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),6348,112,6518,"0,017183185",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"29,68","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_043,21,36164668,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr403Asn/c.1207T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),3605,64,3696,"0,0173160173",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"29,69","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_045,21,36164668,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr403Asn/c.1207T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),4022,90,4153,"0,0216710811",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"29,61","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_046,21,36164668,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr403Asn/c.1207T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),4690,99,4835,"0,020475698",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"29,51","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_047,21,36164668,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr403Asn/c.1207T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),6550,129,6731,"0,0191650572",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"29,57","14,89"
"low bq, many samples",UPN2_048,21,36164668,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr403Asn/c.1207T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),6848,157,7071,"0,0222033659",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"29,44","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_049,21,36164668,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr403Asn/c.1207T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),4010,80,4118,"0,0194269063",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"29,73","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_050,21,36164668,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr403Asn/c.1207T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),3371,74,3484,"0,0212399541",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"29,75","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_051,21,36164668,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr403Asn/c.1207T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),4528,81,4641,"0,0174531351",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"29,94","14,44"
"low bq, many samples",UPN2_052,21,36164668,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr403Asn/c.1207T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),3719,93,3841,"0,0242124447",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"29,75","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_053,21,36164668,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr403Asn/c.1207T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),5329,103,5489,"0,0187648023",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"29,61","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_054,21,36164668,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr403Asn/c.1207T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),2934,65,3024,"0,021494709",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"29,75","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_055,21,36164668,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr403Asn/c.1207T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),5612,115,5785,"0,0198789974",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"29,66","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_056,21,36164668,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr403Asn/c.1207T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),2370,47,2430,"0,0193415638",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"29,37","14,66"
"low bq, many samples",UPN2_057,21,36164668,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr403Asn/c.1207T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),3170,72,3262,"0,0220723483",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"29,52","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_058,21,36164668,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr403Asn/c.1207T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),3907,69,4007,"0,0172198652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"29,54","14,58"
"low bq, bad alignment, many samples",UPN2_013,21,36164668,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr403Asn/c.1207T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),725,21,749,"0,0280373832",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"26,25",14
"low bq, bad alignment, low freq, many artifacts",UPN2_099,21,36164668,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr403Asn/c.1207T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),1208,22,1242,"0,0177133655",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,07",Deleterious,0,Damaging,"26,97",14
"low bq, many samples",UPN2_041,21,36164671,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser402Pro/c.1204T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),12071,278,12474,"0,0222863556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"3,31",Neutral,1,Tolerated,"29,4","19,25"
"low bq, low freq, many artifacts, many samples",UPN2_042,21,36164671,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser402Pro/c.1204T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6324,121,6515,"0,0185725249",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"3,31",Neutral,1,Tolerated,"29,4","16,26"
"low bq, low freq, many artifacts, many samples",UPN2_043,21,36164671,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser402Pro/c.1204T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3582,74,3696,"0,020021645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"3,31",Neutral,1,Tolerated,"29,43","16,61"
"low bq, low freq, many artifacts, many samples",UPN2_045,21,36164671,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser402Pro/c.1204T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4024,81,4153,"0,019503973",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"3,31",Neutral,1,Tolerated,"29,56","16,8"
"low bq, low freq, many artifacts, many samples",UPN2_046,21,36164671,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser402Pro/c.1204T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4691,93,4832,"0,0192466887",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"3,31",Neutral,1,Tolerated,"29,3","16,03"
"low bq, low freq, many artifacts, many samples",UPN2_048,21,36164671,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser402Pro/c.1204T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),6861,138,7070,"0,0195190948",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"3,31",Neutral,1,Tolerated,"29,34","15,74"
"low bq, low freq, many artifacts, many samples",UPN2_050,21,36164671,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser402Pro/c.1204T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3389,62,3483,"0,0178007465",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"3,31",Neutral,1,Tolerated,"29,52","17,27"
"low bq, low freq, many artifacts, many samples",UPN2_051,21,36164671,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser402Pro/c.1204T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4499,80,4638,"0,0172488141",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"3,31",Neutral,1,Tolerated,30,"15,59"
"low bq, low freq, many artifacts, many samples",UPN2_052,21,36164671,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser402Pro/c.1204T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3705,82,3841,"0,0213486071",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"3,31",Neutral,1,Tolerated,"29,46","17,82"
"low bq, low freq, many artifacts, many samples",UPN2_055,21,36164671,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser402Pro/c.1204T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5621,98,5783,"0,0169462217",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"3,31",Neutral,1,Tolerated,"29,46","16,06"
"low bq, low freq, many artifacts, many samples",UPN2_057,21,36164671,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser402Pro/c.1204T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3174,46,3259,"0,0141147591",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"3,31",Neutral,1,Tolerated,"29,42","16,22"
"low bq, low freq, many artifacts, many samples",UPN2_058,21,36164671,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser402Pro/c.1204T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3895,75,4006,"0,0187219171",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"3,31",Neutral,1,Tolerated,"29,51","17,11"
"low bq, bad alignment, many samples",UPN2_013,21,36164671,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser402Pro/c.1204T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),702,40,749,"0,0534045394",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"3,31",Neutral,1,Tolerated,"26,39","17,65"
"low bq, bad alignment, many samples",UPN2_071,21,36164671,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser402Pro/c.1204T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),368,20,403,"0,0496277916",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"3,31",Neutral,1,Tolerated,"26,59","14,9"
"low bq, bad alignment",UPN2_099,21,36164671,A,G,missense_variant(MODERATE|MISSENSE|Tcc/Ccc|p.Ser402Pro/c.1204T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1176,45,1242,"0,0362318841",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"3,31",Neutral,1,Tolerated,"26,94","14,49"
"low bq, low freq, many artifacts",UPN2_052,21,36164671,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser402Thr/c.1204T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),3705,39,3841,"0,0101536058",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,59",Neutral,66,Tolerated,"29,46","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_089,21,36164677,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser400Ala/c.1198T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1106,22,1145,"0,0192139738",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,7",Neutral,74,Tolerated,"34,55",14
"low bq, many samples",UPN2_090,21,36164677,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser400Ala/c.1198T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),949,27,996,"0,0271084337",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,7",Neutral,74,Tolerated,"34,72","14,48"
"low bq, many samples",UPN2_091,21,36164677,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser400Ala/c.1198T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1340,33,1399,"0,0235882773",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,7",Neutral,74,Tolerated,"34,48","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_094,21,36164677,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser400Ala/c.1198T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1355,22,1395,"0,0157706093",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,7",Neutral,74,Tolerated,"34,33","14,82"
"low bq, many samples",UPN2_096,21,36164677,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser400Ala/c.1198T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1691,48,1760,"0,0272727273",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,7",Neutral,74,Tolerated,"34,31","14,15"
"low bq, low freq, many artifacts, many samples",UPN2_097,21,36164677,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser400Ala/c.1198T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1942,33,2000,"0,0165",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,7",Neutral,74,Tolerated,"34,64",14
"low bq, many samples",UPN2_098,21,36164677,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser400Ala/c.1198T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1428,42,1491,"0,0281690141",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,7",Neutral,74,Tolerated,"34,49","15,12"
"low bq, many samples",UPN2_100,21,36164677,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser400Ala/c.1198T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1362,38,1415,"0,0268551237",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,7",Neutral,74,Tolerated,"34,48","14,37"
"low bq, many samples",UPN2_101,21,36164677,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser400Ala/c.1198T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1032,39,1088,"0,0358455882",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,7",Neutral,74,Tolerated,"34,6",14
"low bq, many samples",UPN2_102,21,36164677,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser400Ala/c.1198T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1280,37,1336,"0,0276946108",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,7",Neutral,74,Tolerated,"34,5","14,19"
"low bq, low freq, many artifacts, many samples",UPN2_103,21,36164677,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser400Ala/c.1198T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1441,27,1490,"0,0181208054",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,7",Neutral,74,Tolerated,"34,31","15,44"
"low bq, many samples",UPN2_104,21,36164677,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser400Ala/c.1198T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1527,40,1601,"0,0249843848",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,7",Neutral,74,Tolerated,"34,53","14,18"
"low bq, many samples",UPN2_105,21,36164677,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser400Ala/c.1198T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),986,23,1025,"0,0224390244",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,7",Neutral,74,Tolerated,"34,43","15,7"
"low bq, low freq, many artifacts, many samples",UPN2_106,21,36164677,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser400Ala/c.1198T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2716,52,2822,"0,0184266478",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,7",Neutral,74,Tolerated,"34,44","15,12"
"low bq, many samples",UPN2_107,21,36164677,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser400Ala/c.1198T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2618,62,2726,"0,0227439472",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,7",Neutral,74,Tolerated,"34,26","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_108,21,36164677,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser400Ala/c.1198T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2630,59,2735,"0,0215722121",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,7",Neutral,74,Tolerated,"34,54","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_109,21,36164677,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser400Ala/c.1198T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1922,39,1993,"0,0195684897",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,7",Neutral,74,Tolerated,"34,33",14
"low bq, low freq, many artifacts, many samples",UPN2_110,21,36164677,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser400Ala/c.1198T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2494,44,2564,"0,0171606864",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,7",Neutral,74,Tolerated,"34,51","14,16"
low bq,UPN2_111,21,36164677,A,C,missense_variant(MODERATE|MISSENSE|Tcg/Gcg|p.Ser400Ala/c.1198T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1562,44,1655,"0,0265861027",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,7",Neutral,74,Tolerated,"34,3",14
"low bq, low freq, many artifacts, many samples",UPN2_014,21,36164677,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser400Pro/c.1198T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2279,31,2321,"0,0133563119",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,5",Neutral,209,Tolerated,"33,74","19,77"
"low bq, low freq, many artifacts, many samples",UPN2_015,21,36164677,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser400Pro/c.1198T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4115,49,4187,"0,0117028899",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,5",Neutral,209,Tolerated,"33,47","15,8"
"low bq, low freq, many artifacts, many samples",UPN2_018,21,36164677,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser400Pro/c.1198T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1893,23,1926,"0,0119418484",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,5",Neutral,209,Tolerated,"33,38","19,74"
"low bq, low freq, many artifacts, many samples",UPN2_022,21,36164677,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser400Pro/c.1198T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2498,31,2554,"0,012137823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,5",Neutral,209,Tolerated,"33,62","18,97"
"low bq, low freq, many artifacts, many samples",UPN2_026,21,36164677,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser400Pro/c.1198T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2586,28,2631,"0,0106423413",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,5",Neutral,209,Tolerated,"33,7","17,93"
"low bq, low freq, many artifacts, many samples",UPN2_029,21,36164677,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser400Pro/c.1198T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1947,36,1998,"0,018018018",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,5",Neutral,209,Tolerated,"33,76","17,06"
"low bq, low freq, many artifacts, many samples",UPN2_030,21,36164677,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser400Pro/c.1198T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3144,39,3203,"0,0121760849",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,5",Neutral,209,Tolerated,"33,47","17,85"
"low bq, low freq, many artifacts, many samples",UPN2_033,21,36164677,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser400Pro/c.1198T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2009,28,2056,"0,013618677",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,5",Neutral,209,Tolerated,"33,62","20,14"
"low bq, low freq, many artifacts, many samples",UPN2_035,21,36164677,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser400Pro/c.1198T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3375,44,3445,"0,0127721335",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,5",Neutral,209,Tolerated,"33,63","21,23"
"low bq, many samples",UPN2_006,21,36164677,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser400Pro/c.1198T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),970,29,1011,"0,0286844708",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,5",Neutral,209,Tolerated,"32,82","17,03"
"low bq, low freq, many artifacts, many samples",UPN2_037,21,36164677,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser400Pro/c.1198T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4048,44,4130,"0,010653753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,5",Neutral,209,Tolerated,"33,42","19,91"
"low bq, low freq, many artifacts, many samples",UPN2_051,21,36164677,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser400Pro/c.1198T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3589,37,3655,"0,010123119",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,5",Neutral,209,Tolerated,"33,83","23,41"
"low bq, low freq, many artifacts, many samples",UPN2_038,21,36164677,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser400Pro/c.1198T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4329,59,4413,"0,0133695898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,5",Neutral,209,Tolerated,"33,58","19,49"
"low bq, low freq, many artifacts, many samples",UPN2_039,21,36164677,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser400Pro/c.1198T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2934,34,2989,"0,0113750418",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,5",Neutral,209,Tolerated,"33,45","16,47"
"low bq, low freq, many artifacts, many samples",UPN2_007,21,36164677,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser400Pro/c.1198T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2361,41,2416,"0,0169701987",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,5",Neutral,209,Tolerated,"32,56","19,17"
"low bq, low freq, many artifacts, many samples",UPN2_008,21,36164677,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser400Pro/c.1198T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2936,39,3000,"0,013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,5",Neutral,209,Tolerated,"32,37","17,38"
"low bq, low freq, many artifacts, many samples",UPN2_009,21,36164677,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser400Pro/c.1198T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2541,29,2590,"0,0111969112",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,5",Neutral,209,Tolerated,"32,53","17,66"
"low bq, low freq, many artifacts, many samples",UPN2_055,21,36164677,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser400Pro/c.1198T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4646,51,4734,"0,0107731305",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,5",Neutral,209,Tolerated,"33,73","20,96"
"low bq, low freq, many artifacts, many samples",UPN2_090,21,36164677,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser400Pro/c.1198T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),949,20,996,"0,0200803213",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,5",Neutral,209,Tolerated,"34,72","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_057,21,36164677,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser400Pro/c.1198T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2614,28,2660,"0,0105263158",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,5",Neutral,209,Tolerated,"33,81","18,89"
"low bq, low freq, many artifacts, many samples",UPN2_091,21,36164677,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser400Pro/c.1198T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1340,25,1399,"0,0178699071",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,5",Neutral,209,Tolerated,"34,48","16,64"
"low bq, low freq, many artifacts, many samples",UPN2_096,21,36164677,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser400Pro/c.1198T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1691,21,1760,"0,0119318182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,5",Neutral,209,Tolerated,"34,31","15,9"
"low bq, low freq, many artifacts, many samples",UPN2_097,21,36164677,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser400Pro/c.1198T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1942,23,2000,"0,0115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,5",Neutral,209,Tolerated,"34,64","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_104,21,36164677,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser400Pro/c.1198T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1527,30,1601,"0,0187382886",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,5",Neutral,209,Tolerated,"34,53","18,4"
"low bq, low freq, many artifacts, many samples",UPN2_106,21,36164677,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser400Pro/c.1198T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2716,48,2822,"0,0170092133",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,5",Neutral,209,Tolerated,"34,44","16,21"
"low bq, low freq, many artifacts, many samples",UPN2_107,21,36164677,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser400Pro/c.1198T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2618,41,2726,"0,0150403522",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,5",Neutral,209,Tolerated,"34,26","16,15"
"low bq, low freq, many artifacts, many samples",UPN2_108,21,36164677,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser400Pro/c.1198T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2630,44,2735,"0,0160877514",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,5",Neutral,209,Tolerated,"34,54","18,59"
"low bq, low freq, many artifacts, many samples",UPN2_109,21,36164677,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser400Pro/c.1198T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1922,30,1993,"0,0150526844",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,5",Neutral,209,Tolerated,"34,33","15,9"
low bq,UPN2_111,21,36164677,A,G,missense_variant(MODERATE|MISSENSE|Tcg/Ccg|p.Ser400Pro/c.1198T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1562,45,1655,"0,0271903323",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,5",Neutral,209,Tolerated,"34,3","19,07"
"inspected, many artifacts",UPN2_057,21,36164680,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser399Gly/c.1195A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2553,34,2619,"0,0129820542",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,91",Neutral,"0,111",Tolerated,"25,78","33,94"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_015,21,36164680,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser399Arg/c.1195A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4045,48,4118,"0,0116561438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,2,Damaging,"23,47","14,29"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_018,21,36164680,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser399Arg/c.1195A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1864,25,1893,"0,0132065504",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,2,Damaging,"23,66","14,88"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_019,21,36164680,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser399Arg/c.1195A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1954,31,1990,"0,0155778894",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,2,Damaging,"23,34","14,71"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_020,21,36164680,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser399Arg/c.1195A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1271,20,1295,"0,0154440154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,2,Damaging,"23,79",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_021,21,36164680,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser399Arg/c.1195A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1734,20,1765,"0,0113314448",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,2,Damaging,"23,82","15,1"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_022,21,36164680,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser399Arg/c.1195A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2471,29,2509,"0,0115583898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,2,Damaging,"23,52","14,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_023,21,36164680,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser399Arg/c.1195A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2545,30,2588,"0,0115919629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,2,Damaging,"23,84","14,43"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_041,21,36164680,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser399Arg/c.1195A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),9723,128,9940,"0,0128772636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,2,Damaging,"25,64","14,58"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_025,21,36164680,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser399Arg/c.1195A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3405,48,3474,"0,0138169257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,2,Damaging,"24,13","15,1"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_026,21,36164680,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser399Arg/c.1195A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2547,30,2594,"0,0115651503",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,2,Damaging,"23,49","14,23"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_027,21,36164680,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser399Arg/c.1195A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2714,33,2762,"0,0119478639",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,2,Damaging,"23,4","14,67"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,21,36164680,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser399Arg/c.1195A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5093,77,5192,"0,0148305085",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,2,Damaging,"25,66","14,29"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_028,21,36164680,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser399Arg/c.1195A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1870,21,1902,"0,0110410095",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,2,Damaging,"23,01","14,95"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_043,21,36164680,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser399Arg/c.1195A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2903,36,2953,"0,0121909922",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,2,Damaging,26,"14,5"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_029,21,36164680,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser399Arg/c.1195A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1918,27,1953,"0,0138248848",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,2,Damaging,"23,74","15,15"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_045,21,36164680,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser399Arg/c.1195A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3294,52,3366,"0,0154486037",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,2,Damaging,"25,57","15,06"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,21,36164680,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser399Arg/c.1195A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3847,52,3922,"0,0132585416",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,2,Damaging,"25,61","14,48"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,21,36164680,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser399Arg/c.1195A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5288,58,5404,"0,0107327905",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,2,Damaging,"25,6","14,62"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_048,21,36164680,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser399Arg/c.1195A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5540,77,5658,"0,0136090491",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,2,Damaging,"25,74","14,49"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,21,36164680,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser399Arg/c.1195A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3276,39,3327,"0,0117222723",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,2,Damaging,"25,94","17,85"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,21,36164680,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser399Arg/c.1195A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2743,32,2785,"0,0114901257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,2,Damaging,"25,88","17,84"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_037,21,36164680,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser399Arg/c.1195A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3998,57,4071,"0,0140014738",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,2,Damaging,"23,05","14,56"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,21,36164680,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser399Arg/c.1195A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3535,52,3609,"0,0144084234",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,2,Damaging,"26,1","14,52"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,21,36164680,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser399Arg/c.1195A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3010,46,3077,"0,0149496263",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,2,Damaging,"25,38","14,96"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_038,21,36164680,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser399Arg/c.1195A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4274,55,4344,"0,0126611418",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,2,Damaging,"23,81","15,2"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_039,21,36164680,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser399Arg/c.1195A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2889,37,2935,"0,0126064736",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,2,Damaging,"23,19","14,35"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,21,36164680,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser399Arg/c.1195A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4360,62,4451,"0,0139294541",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,2,Damaging,"25,76","15,21"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_054,21,36164680,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser399Arg/c.1195A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2401,39,2453,"0,0158988993",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,2,Damaging,"25,49","14,56"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_007,21,36164680,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser399Arg/c.1195A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2323,35,2364,"0,0148054146",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,2,Damaging,"23,44","14,37"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_008,21,36164680,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser399Arg/c.1195A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2862,60,2939,"0,0204151072",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,2,Damaging,"22,73","14,53"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_009,21,36164680,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser399Arg/c.1195A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2509,35,2555,"0,0136986301",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,2,Damaging,"22,9","14,57"
"low bq, bad alignment, many samples",UPN2_011,21,36164680,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser399Arg/c.1195A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1680,44,1730,"0,025433526",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,2,Damaging,"23,19",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,21,36164680,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser399Arg/c.1195A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4589,56,4669,"0,011994003",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,2,Damaging,"25,68","16,02"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,21,36164680,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser399Arg/c.1195A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1887,29,1922,"0,0150884495",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,2,Damaging,"25,78","14,69"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,21,36164680,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser399Arg/c.1195A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2553,31,2619,"0,0118365788",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,2,Damaging,"25,78","14,23"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_058,21,36164680,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser399Arg/c.1195A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3153,42,3213,"0,0130718954",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,2,Damaging,"25,67","14,31"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_012,21,36164680,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser399Arg/c.1195A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1183,26,1212,"0,0214521452",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,2,Damaging,"22,98","14,77"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_040,21,36164680,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser399Arg/c.1195A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2430,26,2471,"0,0105220558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,2,Damaging,"23,81","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_096,21,36164680,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser399Arg/c.1195A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1666,21,1690,"0,0124260355",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,2,Damaging,"27,32",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_107,21,36164680,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser399Arg/c.1195A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2574,29,2611,"0,0111068556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,2,Damaging,"26,78","14,24"
"low bq, bad alignment, low freq, many artifacts",UPN2_111,21,36164680,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser399Arg/c.1195A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1547,20,1572,"0,0127226463",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,49",Neutral,2,Damaging,"26,37",14
low bq,UPN2_006,21,36164683,C,T,missense_variant(MODERATE|MISSENSE|Gcc/Acc|p.Ala398Thr/c.1192G>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),955,24,980,"0,0244897959",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"1,14",Neutral,1,Tolerated,"34,56","18,54"
"low bq, bad alignment, low freq, many artifacts",UPN2_045,21,36164685,T,G,missense_variant(MODERATE|MISSENSE|cAa/cCa|p.Gln397Pro/c.1190A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3313,36,3366,"0,0106951872",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,12,Damaging,"26,43",14
"inspected, many artifacts",UPN2_056,21,36164700,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln392Leu/c.1175A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1889,27,1923,"0,0140405616",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,99",Deleterious,"0,001",Damaging,"33,35","34,74"
"inspected, many artifacts",UPN2_050,21,36164709,G,A,missense_variant(MODERATE|MISSENSE|tCg/tTg|p.Ser389Leu/c.1166C>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),2758,30,2788,"0,0107604017",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,09",Deleterious,"0,002",Damaging,"35,2","33,8"
"low freq, many artifacts, many samples",UPN2_036,21,36164719,G,T,missense_variant(MODERATE|MISSENSE|Ccc/Acc|p.Pro386Thr/c.1156C>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),2219,28,2249,"0,0124499778",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,57",Deleterious,1,Damaging,"35,37","32,14"
"low freq, many artifacts, many samples",UPN2_091,21,36164719,G,T,missense_variant(MODERATE|MISSENSE|Ccc/Acc|p.Pro386Thr/c.1156C>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),1340,21,1362,"0,0154185022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,57",Deleterious,1,Damaging,"35,19",32
"low freq, many artifacts, many samples",UPN2_061,21,36164722,AG,A,frameshift_variant(HIGH||ccc/|p.Tyr385fs/c.1152delC|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),1330,20,1351,"0,014803849",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,08",NA
"low freq, many artifacts, many samples",UPN2_080,21,36164729,C,CG,frameshift_variant(HIGH||ccg/ccCg|p.Pro383fs/c.1145dupC|480|RUNX1|protein_coding|CODING|ENST00000437180|9|CG),2685,31,2691,"0,0115198811",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,33",NA
"inspected, many artifacts",UPN2_044,21,36164731,G,A,missense_variant(MODERATE|MISSENSE|Ccg/Tcg|p.Pro382Ser/c.1144C>T|480|RUNX1|protein_coding|CODING|ENST00000437180|9|A),2632,27,2662,"0,0101427498",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,81",Deleterious,"0,07",Tolerated,"35,48","34,89"
"low freq, many artifacts, many samples",UPN2_006,21,36164732,CA,C,frameshift_variant(HIGH||ctg/|p.Leu381fs/c.1142delT|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),5003,53,5114,"0,0103637075",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,43",NA
"low freq, many artifacts, many samples",UPN2_075,21,36164733,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu381Gln/c.1142T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),1906,22,1950,"0,0112820513",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,25",Deleterious,0,Damaging,"35,23","34,82"
"low freq, many artifacts, many samples",UPN2_044,21,36164735,G,GT,frameshift_variant+stop_gained(HIGH||tac/taAc|p.Tyr380fs/c.1139dupA|480|RUNX1|protein_coding|CODING|ENST00000437180|9|GT),2656,52,2662,"0,0195341848",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,39",NA
"low freq, many artifacts, many samples",UPN2_060,21,36164744,G,C,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr377*/c.1131C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1241,24,1268,"0,0189274448",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,26","34,92"
"many artifacts, low freq",UPN2_044,21,36164772,A,G,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met368Thr/c.1103T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2580,31,2661,"0,0116497557",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,82",Deleterious,"0,002",Damaging,"34,23","35,03"
"many artifacts, low freq",UPN2_044,21,36164772,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met368Lys/c.1103T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),2580,45,2661,"0,0169109357",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,3",Deleterious,"0,001",Damaging,"34,23","31,87"
"low bq, low freq, many artifacts, many samples",UPN2_062,21,36164778,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile366Ser/c.1097T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2145,26,2173,"0,0119650253",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,79",Deleterious,134,Tolerated,"30,82","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_071,21,36164784,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile364Ser/c.1091T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3627,40,3692,"0,0108342362",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,75",Neutral,53,Tolerated,"30,72","14,95"
"low bq, many samples",UPN2_060,21,36164796,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val360Gly/c.1079T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1059,31,1093,"0,0283623056",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,98",Deleterious,"0,18",Tolerated,"29,06","16,94"
"low bq, many samples",UPN2_061,21,36164796,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val360Gly/c.1079T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1220,28,1253,"0,0223463687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,98",Deleterious,"0,18",Tolerated,"28,81","14,5"
"low bq, many samples",UPN2_062,21,36164796,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val360Gly/c.1079T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2091,71,2172,"0,0326887661",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,98",Deleterious,"0,18",Tolerated,"28,21","15,92"
"low bq, many samples",UPN2_063,21,36164796,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val360Gly/c.1079T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1183,32,1216,"0,0263157895",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,98",Deleterious,"0,18",Tolerated,"28,53","15,78"
"low bq, low freq, many artifacts, many samples",UPN2_071,21,36164796,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val360Gly/c.1079T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3595,80,3692,"0,0216684724",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,98",Deleterious,"0,18",Tolerated,"28,76","15,3"
"low bq, many samples",UPN2_072,21,36164796,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val360Gly/c.1079T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2589,60,2658,"0,0225733634",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,98",Deleterious,"0,18",Tolerated,"28,62","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_075,21,36164796,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val360Gly/c.1079T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1771,37,1823,"0,020296215",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,98",Deleterious,"0,18",Tolerated,"29,46","15,89"
"low bq, many samples",UPN2_076,21,36164796,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val360Gly/c.1079T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),942,27,976,"0,0276639344",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,98",Deleterious,"0,18",Tolerated,"27,98","14,74"
"low bq, many samples",UPN2_077,21,36164796,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val360Gly/c.1079T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),709,21,732,"0,0286885246",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,98",Deleterious,"0,18",Tolerated,"28,12",15
"low bq, many samples",UPN2_078,21,36164796,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val360Gly/c.1079T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1430,35,1465,"0,023890785",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,98",Deleterious,"0,18",Tolerated,"28,27","16,91"
"low bq, many samples",UPN2_080,21,36164796,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val360Gly/c.1079T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2407,61,2471,"0,0246863618",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,98",Deleterious,"0,18",Tolerated,"28,49","15,21"
"low bq, many samples",UPN2_081,21,36164796,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val360Gly/c.1079T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3968,99,4081,"0,0242587601",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,98",Deleterious,"0,18",Tolerated,"28,84","16,26"
"low bq, many samples",UPN2_083,21,36164796,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val360Gly/c.1079T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),939,24,963,"0,0249221184",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,98",Deleterious,"0,18",Tolerated,"28,1","15,96"
low bq,UPN2_084,21,36164796,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val360Gly/c.1079T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),971,27,1001,"0,026973027",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,98",Deleterious,"0,18",Tolerated,"28,1","15,93"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,21,36164803,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr358Pro/c.1072A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2432,32,2471,"0,0129502226",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,6",Deleterious,118,Tolerated,"26,3","14,78"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,21,36164803,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr358Pro/c.1072A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4222,43,4279,"0,0100490769",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,6",Deleterious,118,Tolerated,"26,33","14,6"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,21,36164803,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr358Pro/c.1072A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2355,31,2391,"0,0129652865",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,6",Deleterious,118,Tolerated,"26,23","14,68"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,21,36164803,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr358Pro/c.1072A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1905,25,1932,"0,0129399586",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,6",Deleterious,118,Tolerated,"26,45","14,52"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,21,36164803,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr358Pro/c.1072A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2858,30,2894,"0,0103662751",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,6",Deleterious,118,Tolerated,"26,46","14,43"
"low bq, bad alignment, low freq, many artifacts",UPN2_084,21,36164803,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr358Pro/c.1072A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1927,22,1949,"0,0112878399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,6",Deleterious,118,Tolerated,"26,44",14
"low bq, low freq, many artifacts, many samples",UPN2_060,21,36164815,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr354Pro/c.1060A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2125,27,2165,"0,0124711316",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,351,Tolerated,"30,57","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_083,21,36164815,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr354Pro/c.1060A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1886,23,1921,"0,0119729308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,351,Tolerated,"30,32","14,57"
"inspected, many artifacts",UPN2_049,21,36164818,A,AGGCG,frameshift_variant(HIGH||gcc/gccCGCC|p.Phe353fs/c.1053_1056dupCGCC|480|RUNX1|protein_coding|CODING|ENST00000437180|9|AGGCG),23562,439,23863,"0,0183966811",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,79",NA
"inspected, many artifacts",UPN2_063,21,36164821,C,T,missense_variant(MODERATE|MISSENSE|Gcc/Acc|p.Ala352Thr/c.1054G>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),2381,28,2413,"0,0116038127",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,"0,665",Tolerated,"33,34","31,11"
"inspected, many artifacts",UPN2_082,21,36164821,C,T,missense_variant(MODERATE|MISSENSE|Gcc/Acc|p.Ala352Thr/c.1054G>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),1406,21,1432,"0,0146648045",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,85",Neutral,"0,665",Tolerated,"33,67","33,95"
"inspected, many artifacts",UPN2_065,21,36164824,C,T,missense_variant(MODERATE|MISSENSE|Ggc/Agc|p.Gly351Ser/c.1051G>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),1175,20,1199,"0,0166805671",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,48",Neutral,"0,082",Tolerated,"30,86","27,1"
"low bq, low freq, many artifacts, many samples",UPN2_061,21,36164829,T,G,missense_variant(MODERATE|MISSENSE|tAt/tCt|p.Tyr349Ser/c.1046A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2450,29,2483,"0,0116794201",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,03",Deleterious,2,Damaging,"29,29","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_062,21,36164829,T,G,missense_variant(MODERATE|MISSENSE|tAt/tCt|p.Tyr349Ser/c.1046A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4250,52,4307,"0,0120733689",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,03",Deleterious,2,Damaging,"29,21","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_063,21,36164829,T,G,missense_variant(MODERATE|MISSENSE|tAt/tCt|p.Tyr349Ser/c.1046A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2385,31,2416,"0,0128311258",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,03",Deleterious,2,Damaging,"29,11","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_071,21,36164829,T,G,missense_variant(MODERATE|MISSENSE|tAt/tCt|p.Tyr349Ser/c.1046A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),7219,86,7327,"0,0117374096",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,03",Deleterious,2,Damaging,"29,1","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_072,21,36164829,T,G,missense_variant(MODERATE|MISSENSE|tAt/tCt|p.Tyr349Ser/c.1046A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5195,60,5269,"0,01138736",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,03",Deleterious,2,Damaging,"28,87","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_076,21,36164829,T,G,missense_variant(MODERATE|MISSENSE|tAt/tCt|p.Tyr349Ser/c.1046A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1914,20,1941,"0,010303967",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,03",Deleterious,2,Damaging,"29,07","15,3"
"low bq, low freq, many artifacts, many samples",UPN2_077,21,36164829,T,G,missense_variant(MODERATE|MISSENSE|tAt/tCt|p.Tyr349Ser/c.1046A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1428,21,1455,"0,0144329897",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,03",Deleterious,2,Damaging,"28,85","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_078,21,36164829,T,G,missense_variant(MODERATE|MISSENSE|tAt/tCt|p.Tyr349Ser/c.1046A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2853,51,2918,"0,0174777245",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,03",Deleterious,2,Damaging,"29,11","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_080,21,36164829,T,G,missense_variant(MODERATE|MISSENSE|tAt/tCt|p.Tyr349Ser/c.1046A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4845,54,4906,"0,0110069303",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,03",Deleterious,2,Damaging,"29,11","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_081,21,36164829,T,G,missense_variant(MODERATE|MISSENSE|tAt/tCt|p.Tyr349Ser/c.1046A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),7969,94,8089,"0,0116207195",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,03",Deleterious,2,Damaging,"29,18","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_083,21,36164829,T,G,missense_variant(MODERATE|MISSENSE|tAt/tCt|p.Tyr349Ser/c.1046A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1885,26,1921,"0,0135346174",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,03",Deleterious,2,Damaging,"28,9","16,73"
"low bq, low freq, many artifacts",UPN2_087,21,36164829,T,G,missense_variant(MODERATE|MISSENSE|tAt/tCt|p.Tyr349Ser/c.1046A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1325,23,1353,"0,0169992609",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,03",Deleterious,2,Damaging,"29,3","15,52"
"low bq, low freq, many artifacts, many samples",UPN2_047,21,36164830,A,T,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr349Asn/c.1045T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),39992,406,40527,"0,0100180127",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,83",Deleterious,1,Damaging,"33,49","21,95"
"low bq, low freq, many artifacts, many samples",UPN2_052,21,36164830,A,T,missense_variant(MODERATE|MISSENSE|Tat/Aat|p.Tyr349Asn/c.1045T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),22782,239,23092,"0,0103499047",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,83",Deleterious,1,Damaging,"33,42","21,95"
"inspected, many artifacts",UPN2_044,21,36164831,G,T,missense_variant(MODERATE|MISSENSE|caC/caA|p.His348Gln/c.1044C>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),3724,81,3805,"0,0212877792",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,1",Deleterious,"0,002",Damaging,"34,73","33,78"
"inspected, many artifacts",UPN2_060,21,36164834,C,T,missense_variant(MODERATE|MISSENSE|atG/atA|p.Met347Ile/c.1041G>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),2127,33,2166,"0,0152354571",0,0,0,0,1,0,0,1,2,"0,0117",NO,NO,NO,O,NO,rs370114565,NO,"2,49E-005",NO,NO,"-2,88",Deleterious,"0,006",Damaging,"31,41","31,55"
"low bq, low freq, many artifacts, many samples",UPN2_062,21,36164835,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met347Arg/c.1040T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4230,45,4307,"0,0104481077",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,63",Deleterious,0,Damaging,"28,9","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_063,21,36164835,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met347Arg/c.1040T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2346,35,2417,"0,0144807613",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,63",Deleterious,0,Damaging,"29,16","15,63"
"low bq, low freq, many artifacts, many samples",UPN2_072,21,36164835,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met347Arg/c.1040T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),5169,54,5270,"0,0102466793",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,63",Deleterious,0,Damaging,"28,99","15,56"
"low bq, low freq, many artifacts",UPN2_084,21,36164835,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met347Arg/c.1040T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1928,25,1968,"0,012703252",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,63",Deleterious,0,Damaging,"28,73","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_044,21,36164835,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met347Lys/c.1040T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),3759,45,3806,"0,0118234367",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,5",Deleterious,0,Damaging,"31,92","17,02"
"low bq, low freq, many artifacts, many samples",UPN2_049,21,36164835,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met347Lys/c.1040T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),23486,239,23878,"0,0100092135",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,5",Deleterious,0,Damaging,"31,81","18,07"
"low bq, low freq, many artifacts, many samples",UPN2_056,21,36164835,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met347Lys/c.1040T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),11879,122,12102,"0,0100809784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,5",Deleterious,0,Damaging,"31,78","18,07"
"low bq, low freq, many artifacts, many samples",UPN2_001,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),8307,86,8436,"0,0101944049",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"28,75","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_003,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2080,26,2112,"0,0123106061",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"28,54","17,38"
"low bq, low freq, many artifacts, many samples",UPN2_041,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),59578,736,60640,"0,0121372032",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"28,04","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_042,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),37033,475,37718,"0,0125934567",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"27,87","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_043,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),20381,263,20731,"0,0126863152",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"28,13","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_044,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3739,47,3809,"0,0123391966",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"28,09","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_045,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),31635,418,32189,"0,0129858026",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"28,01","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_046,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),24937,314,25379,"0,0123724339",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"27,97","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_047,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),39874,482,40562,"0,0118830432",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"28,02","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_048,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),37230,482,37851,"0,0127341418",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"28,13","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_006,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),8102,87,8223,"0,0105800803",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"28,73","18,37"
"low bq, low freq, many artifacts, many samples",UPN2_049,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),23483,289,23891,"0,0120966054",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,28,"14,62"
"low bq, low freq, many artifacts, many samples",UPN2_050,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),23640,309,24076,"0,0128343579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"27,85","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_051,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),21463,276,21847,"0,0126333135",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"28,03","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_052,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),22664,307,23105,"0,0132871673",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"27,99","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_053,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),28735,374,29245,"0,0127885109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"27,9","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_054,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),15393,216,15714,"0,0137457045",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"27,82","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_055,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),33138,442,33804,"0,0130753757",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"27,97","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_056,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),11903,145,12111,"0,0119725869",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"27,92","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_057,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),20188,266,20576,"0,0129276827",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"27,97","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_058,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),20543,270,20897,"0,0129205149",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"28,15","14,58"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_060,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2125,38,2165,"0,017551963",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"26,27","15,79"
"low bq, low freq, many artifacts, many samples",UPN2_092,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5167,55,5239,"0,0104981867",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"28,01",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2430,49,2486,"0,0197103781",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"26,36","15,08"
"low bq, bad alignment, many samples",UPN2_062,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4178,116,4307,"0,0269328999",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"25,95","14,77"
"low bq, bad alignment, many samples",UPN2_063,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2337,73,2416,"0,0302152318",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"26,12","14,1"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),913,20,933,"0,0214362272",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"26,01",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_065,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1173,24,1199,"0,0200166806",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"26,49","15,04"
"low bq, bad alignment, many samples",UPN2_068,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),882,23,908,"0,0253303965",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"25,98",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),7165,138,7331,"0,0188241713",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"26,23","14,74"
"low bq, bad alignment, many samples",UPN2_072,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5117,122,5268,"0,023158694",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"26,16","14,85"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1096,23,1127,"0,0204081633",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"26,05",14
"low bq, bad alignment, many samples",UPN2_075,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3526,81,3626,"0,0223386652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"26,69","14,09"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1892,36,1940,"0,018556701",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"26,06","15,42"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1421,29,1455,"0,0199312715",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"25,71","15,52"
"low bq, bad alignment, many samples",UPN2_078,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2841,70,2918,"0,0239890336",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"25,69","15,2"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_079,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1210,27,1237,"0,0218270008",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"26,33",14
"low bq, bad alignment, many samples",UPN2_080,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4763,111,4906,"0,0226253567",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"26,11","14,81"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_081,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),7922,139,8090,"0,0171817058",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"26,12","14,94"
"low bq, bad alignment, many samples",UPN2_082,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1384,38,1431,"0,0265548567",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"26,66","15,34"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1879,38,1923,"0,0197607904",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"25,68","14,47"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1917,37,1968,"0,018800813",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"26,15",14
"low bq, bad alignment, many samples",UPN2_085,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),909,21,930,"0,0225806452",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"26,15",14
"low bq, bad alignment",UPN2_087,21,36164844,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp344Ala/c.1031A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1311,34,1353,"0,0251293422",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,45",Deleterious,72,Tolerated,"25,95","15,29"
"inspected, many artifacts",UPN2_006,21,36164845,C,T,missense_variant(MODERATE|MISSENSE|Gac/Aac|p.Asp344Asn/c.1030G>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),8087,125,8221,"0,0152049629",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"4,97E-005",NO,NO,"-1,81",Neutral,"0,355",Tolerated,"34,17","27,57"
"low bq, low freq, many artifacts, many samples",UPN2_060,21,36164850,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile342Ser/c.1025T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2127,27,2165,"0,0124711316",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,7",Deleterious,1,Damaging,"29,97",14
"low bq, low freq, many artifacts, many samples",UPN2_061,21,36164850,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile342Ser/c.1025T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2426,44,2486,"0,017699115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,7",Deleterious,1,Damaging,"30,05","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_062,21,36164850,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile342Ser/c.1025T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4207,86,4305,"0,0199767712",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,7",Deleterious,1,Damaging,"29,88","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_063,21,36164850,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile342Ser/c.1025T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2369,41,2416,"0,0169701987",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,7",Deleterious,1,Damaging,"30,15","14,17"
"low bq, many samples",UPN2_068,21,36164850,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile342Ser/c.1025T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),882,23,908,"0,0253303965",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,7",Deleterious,1,Damaging,"29,72",14
"low bq, many samples",UPN2_069,21,36164850,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile342Ser/c.1025T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1058,25,1088,"0,0229779412",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,7",Deleterious,1,Damaging,"30,09",14
"low bq, low freq, many artifacts, many samples",UPN2_071,21,36164850,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile342Ser/c.1025T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),7164,107,7327,"0,0146035212",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,7",Deleterious,1,Damaging,"30,07","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_072,21,36164850,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile342Ser/c.1025T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),5146,95,5267,"0,0180368331",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,7",Deleterious,1,Damaging,"29,92","15,81"
"low bq, low freq, many artifacts, many samples",UPN2_073,21,36164850,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile342Ser/c.1025T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1100,20,1128,"0,0177304965",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,7",Deleterious,1,Damaging,"30,14","16,8"
"low bq, low freq, many artifacts, many samples",UPN2_075,21,36164850,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile342Ser/c.1025T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3567,43,3627,"0,011855528",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,7",Deleterious,1,Damaging,"30,23","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_076,21,36164850,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile342Ser/c.1025T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1898,34,1940,"0,0175257732",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,7",Deleterious,1,Damaging,"30,27","15,5"
"low bq, low freq, many artifacts, many samples",UPN2_077,21,36164850,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile342Ser/c.1025T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1429,22,1453,"0,0151410874",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,7",Deleterious,1,Damaging,"30,13","16,23"
"low bq, low freq, many artifacts, many samples",UPN2_078,21,36164850,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile342Ser/c.1025T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2839,63,2917,"0,0215975317",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,7",Deleterious,1,Damaging,"29,74","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_080,21,36164850,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile342Ser/c.1025T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4789,94,4906,"0,019160212",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,7",Deleterious,1,Damaging,"30,06","15,64"
"low bq, low freq, many artifacts, many samples",UPN2_081,21,36164850,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile342Ser/c.1025T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),7919,134,8090,"0,0165636588",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,7",Deleterious,1,Damaging,"30,16","15,31"
"low bq, low freq, many artifacts, many samples",UPN2_082,21,36164850,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile342Ser/c.1025T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1390,25,1426,"0,0175315568",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,7",Deleterious,1,Damaging,"30,35","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_083,21,36164850,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile342Ser/c.1025T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1877,34,1923,"0,0176807072",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,7",Deleterious,1,Damaging,"29,99","15,65"
"low bq, low freq, many artifacts, many samples",UPN2_084,21,36164850,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile342Ser/c.1025T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1929,33,1968,"0,0167682927",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,7",Deleterious,1,Damaging,"30,09","16,15"
"low bq, low freq, many artifacts",UPN2_087,21,36164850,A,C,missense_variant(MODERATE|MISSENSE|aTc/aGc|p.Ile342Ser/c.1025T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1315,24,1351,"0,0177646188",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,7",Deleterious,1,Damaging,"29,93","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_061,21,36164851,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile342Leu/c.1024A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2445,35,2486,"0,0140788415",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,19",Neutral,1,Tolerated,"27,8","19,94"
"low bq, low freq, many artifacts, many samples",UPN2_062,21,36164851,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile342Leu/c.1024A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4214,71,4304,"0,0164962825",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,19",Neutral,1,Tolerated,"27,58","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_063,21,36164851,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile342Leu/c.1024A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2381,31,2416,"0,0128311258",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,19",Neutral,1,Tolerated,"27,46","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_071,21,36164851,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile342Leu/c.1024A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),7184,111,7325,"0,0151535836",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,19",Neutral,1,Tolerated,"27,94","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_072,21,36164851,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile342Leu/c.1024A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5172,76,5267,"0,0144294665",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,19",Neutral,1,Tolerated,"27,7","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_076,21,36164851,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile342Leu/c.1024A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1904,24,1940,"0,012371134",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,19",Neutral,1,Tolerated,"27,79",14
"low bq, low freq, many artifacts, many samples",UPN2_077,21,36164851,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile342Leu/c.1024A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1424,22,1453,"0,0151410874",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,19",Neutral,1,Tolerated,"27,63","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_078,21,36164851,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile342Leu/c.1024A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2868,43,2917,"0,0147411724",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,19",Neutral,1,Tolerated,"27,5","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_080,21,36164851,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile342Leu/c.1024A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),4821,72,4905,"0,0146788991",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,19",Neutral,1,Tolerated,"27,63","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_081,21,36164851,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile342Leu/c.1024A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),7927,127,8089,"0,0157003338",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,19",Neutral,1,Tolerated,"27,92","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_083,21,36164851,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile342Leu/c.1024A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1889,30,1923,"0,015600624",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,19",Neutral,1,Tolerated,"27,56",14
"low bq, low freq, many artifacts",UPN2_084,21,36164851,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile342Leu/c.1024A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1926,28,1968,"0,0142276423",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,19",Neutral,1,Tolerated,"27,65",14
"inspected, many artifacts",UPN2_060,21,36164851,TG,T,frameshift_variant(HIGH||tcc/|p.Ile342fs/c.1023delC|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),2134,23,2163,"0,0106333796",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,96",NA
"low bq, low freq, many artifacts",UPN2_063,21,36164854,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser341Ala/c.1021T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2383,27,2416,"0,0111754967",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,47",Neutral,3,Damaging,"31,74","16,15"
"low bq, low freq, many artifacts, many samples",UPN2_060,21,36164859,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu339Arg/c.1016T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2107,42,2164,"0,0194085028",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,1,Damaging,"29,57","16,1"
"low bq, low freq, many artifacts, many samples",UPN2_061,21,36164859,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu339Arg/c.1016T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2416,40,2488,"0,0160771704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,1,Damaging,"29,15",15
"low bq, low freq, many artifacts, many samples",UPN2_062,21,36164859,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu339Arg/c.1016T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4211,79,4308,"0,0183379759",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,1,Damaging,"28,96","14,58"
"low bq, low freq, many artifacts, many samples",UPN2_063,21,36164859,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu339Arg/c.1016T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2359,45,2416,"0,0186258278",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,1,Damaging,"29,41","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_065,21,36164859,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu339Arg/c.1016T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1172,20,1197,"0,0167084378",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,1,Damaging,"29,6","15,3"
"low bq, many samples",UPN2_068,21,36164859,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu339Arg/c.1016T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),875,21,908,"0,0231277533",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,1,Damaging,"29,01","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_071,21,36164859,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu339Arg/c.1016T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),7133,140,7322,"0,0191204589",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,1,Damaging,"29,23","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_072,21,36164859,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu339Arg/c.1016T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),5156,93,5267,"0,0176571103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,1,Damaging,"29,02","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_075,21,36164859,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu339Arg/c.1016T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3547,56,3628,"0,0154355017",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,1,Damaging,"29,48","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_076,21,36164859,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu339Arg/c.1016T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1891,34,1940,"0,0175257732",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,1,Damaging,"29,32","14,59"
"low bq, many samples",UPN2_077,21,36164859,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu339Arg/c.1016T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1411,35,1454,"0,0240715268",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,1,Damaging,"29,14","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_078,21,36164859,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu339Arg/c.1016T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2853,51,2917,"0,0174837161",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,1,Damaging,"29,09","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_080,21,36164859,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu339Arg/c.1016T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4779,99,4905,"0,0201834862",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,1,Damaging,"29,19","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_081,21,36164859,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu339Arg/c.1016T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),7865,156,8087,"0,0192902189",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,1,Damaging,"29,29","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_082,21,36164859,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu339Arg/c.1016T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1388,27,1427,"0,0189208129",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,1,Damaging,"29,32",14
"low bq, low freq, many artifacts, many samples",UPN2_083,21,36164859,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu339Arg/c.1016T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1876,37,1922,"0,0192507804",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,1,Damaging,"29,12","15,68"
"low bq, many samples",UPN2_084,21,36164859,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu339Arg/c.1016T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1913,44,1967,"0,02236909",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,1,Damaging,"28,83","14,89"
"low bq, many samples",UPN2_087,21,36164859,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu339Arg/c.1016T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1309,37,1351,"0,0273871207",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,1,Damaging,"29,41","14,19"
"low bq, low freq, many artifacts",UPN2_088,21,36164859,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu339Arg/c.1016T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),990,21,1015,"0,0206896552",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,14",Deleterious,1,Damaging,"29,71","16,52"
"low bq, many samples",UPN2_059,21,36164868,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe336Cys/c.1007T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),563,22,586,"0,0375426621",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"27,28","14,91"
"low bq, many samples",UPN2_060,21,36164868,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe336Cys/c.1007T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2067,62,2136,"0,0290262172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"27,42","14,71"
"low bq, many samples",UPN2_061,21,36164868,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe336Cys/c.1007T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2344,91,2450,"0,0371428571",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"27,63","14,9"
"low bq, many samples",UPN2_062,21,36164868,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe336Cys/c.1007T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4064,132,4221,"0,0312722104",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"27,36","15,14"
"low bq, many samples",UPN2_063,21,36164868,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe336Cys/c.1007T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2305,65,2381,"0,027299454",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"27,27","15,8"
"low bq, many samples",UPN2_064,21,36164868,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe336Cys/c.1007T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),879,33,916,"0,0360262009",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"27,6","15,73"
"low bq, many samples",UPN2_065,21,36164868,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe336Cys/c.1007T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1139,37,1183,"0,0312764159",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"27,48","14,84"
"low bq, many samples",UPN2_068,21,36164868,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe336Cys/c.1007T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),857,28,892,"0,0313901345",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"27,07","15,11"
"low bq, many samples",UPN2_069,21,36164868,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe336Cys/c.1007T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1034,32,1069,"0,0299345182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"27,55","14,81"
"low bq, many samples",UPN2_070,21,36164868,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe336Cys/c.1007T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),717,21,740,"0,0283783784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"27,31","16,14"
"low bq, many samples",UPN2_071,21,36164868,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe336Cys/c.1007T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6950,237,7231,"0,0327755497",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"27,38","15,01"
"low bq, many samples",UPN2_072,21,36164868,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe336Cys/c.1007T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4991,160,5179,"0,030893995",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"27,22","14,79"
"low bq, many samples",UPN2_073,21,36164868,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe336Cys/c.1007T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1068,31,1109,"0,0279531109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"27,31","14,42"
"low bq, many samples",UPN2_075,21,36164868,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe336Cys/c.1007T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3460,89,3568,"0,0249439462",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"27,57","14,63"
"low bq, many samples",UPN2_076,21,36164868,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe336Cys/c.1007T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1847,61,1911,"0,0319204605",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"27,02","15,46"
"low bq, many samples",UPN2_077,21,36164868,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe336Cys/c.1007T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1382,43,1432,"0,030027933",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"27,33","14,42"
"low bq, many samples",UPN2_078,21,36164868,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe336Cys/c.1007T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2769,82,2865,"0,0286212914",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"27,26","14,78"
"low bq, many samples",UPN2_079,21,36164868,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe336Cys/c.1007T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1175,27,1211,"0,0222956235",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"27,31",14
"low bq, many samples",UPN2_080,21,36164868,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe336Cys/c.1007T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4631,156,4813,"0,0324122169",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"27,48","14,13"
"low bq, many samples",UPN2_081,21,36164868,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe336Cys/c.1007T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),7708,224,7971,"0,0281018693",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"27,45","15,19"
"low bq, many samples",UPN2_082,21,36164868,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe336Cys/c.1007T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1355,48,1409,"0,034066714",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"27,66","15,19"
"low bq, many samples",UPN2_083,21,36164868,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe336Cys/c.1007T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1824,54,1887,"0,0286168521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"27,11","14,37"
"low bq, many samples",UPN2_084,21,36164868,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe336Cys/c.1007T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1826,65,1907,"0,0340849502",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"27,28","14,51"
"low bq, many samples",UPN2_085,21,36164868,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe336Cys/c.1007T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),879,32,917,"0,0348964013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"27,25","15,19"
"low bq, many samples",UPN2_087,21,36164868,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe336Cys/c.1007T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1287,42,1332,"0,0315315315",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"27,08",16
low bq,UPN2_088,21,36164868,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe336Cys/c.1007T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),974,30,1005,"0,0298507463",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,36",Deleterious,0,Damaging,"27,42","14,47"
"low bq, bad alignment, many samples",UPN2_089,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),12414,354,12860,"0,0275272162",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"26,2","14,33"
"low bq, bad alignment, many samples",UPN2_090,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),10529,274,10883,"0,0251768814",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"26,21","14,35"
"low bq, bad alignment, many samples",UPN2_059,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),532,42,581,"0,0722891566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"25,53","14,48"
"low bq, bad alignment, many samples",UPN2_060,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1944,139,2119,"0,0655969797",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"25,63","14,44"
"low bq, bad alignment, many samples",UPN2_091,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),9985,233,10285,"0,022654351",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"26,18","14,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_092,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),5084,111,5224,"0,0212480858",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"26,27","14,26"
"low bq, bad alignment, many samples",UPN2_093,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),7368,191,7609,"0,0251018531",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"26,38","14,52"
"low bq, bad alignment, many samples",UPN2_061,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2199,205,2439,"0,0840508405",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"25,84","14,5"
"low bq, bad alignment, many samples",UPN2_062,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3785,325,4200,"0,0773809524",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"25,73","14,54"
"low bq, bad alignment, many samples",UPN2_063,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2140,182,2367,"0,0768905788",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"25,55","14,42"
"low bq, bad alignment, many samples",UPN2_064,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),818,74,910,"0,0813186813",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"25,86","14,09"
"low bq, bad alignment, many samples",UPN2_065,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1071,86,1178,"0,0730050934",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"25,52","14,69"
"low bq, bad alignment, many samples",UPN2_066,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),214,22,237,"0,0928270042",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"25,61",14
"low bq, bad alignment, many samples",UPN2_067,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),280,20,305,"0,0655737705",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"25,83",14
"low bq, bad alignment, many samples",UPN2_068,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),807,74,890,"0,0831460674",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"25,52","14,45"
"low bq, bad alignment, many samples",UPN2_069,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),954,91,1061,"0,0857681433",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"26,11","14,42"
"low bq, bad alignment, many samples",UPN2_070,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),674,52,733,"0,070941337",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"25,73","14,81"
"low bq, bad alignment, many samples",UPN2_071,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6520,556,7198,"0,0772436788",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"25,65","14,54"
"low bq, bad alignment, many samples",UPN2_072,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4691,393,5155,"0,0762366634",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"25,49","14,28"
"low bq, bad alignment, many samples",UPN2_073,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1017,77,1106,"0,0696202532",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"25,53","14,43"
"low bq, bad alignment, many samples",UPN2_074,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),306,20,329,"0,0607902736",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"25,85",15
"low bq, bad alignment, many samples",UPN2_075,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),3232,267,3551,"0,0751900873",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"25,59","14,52"
"low bq, bad alignment, many samples",UPN2_076,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1705,169,1907,"0,0886208705",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"25,51","14,32"
"low bq, bad alignment, many samples",UPN2_077,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1308,107,1425,"0,0750877193",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"25,79","14,32"
"low bq, bad alignment, many samples",UPN2_078,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),2558,260,2848,"0,0912921348",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"25,88","14,82"
"low bq, bad alignment, many samples",UPN2_079,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1092,94,1206,"0,0779436153",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"25,57","14,07"
"low bq, bad alignment, many samples",UPN2_080,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),4307,396,4789,"0,0826894968",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"25,73","14,7"
"low bq, bad alignment, many samples",UPN2_081,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),7140,677,7932,"0,0853504791",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"25,67","14,55"
"low bq, bad alignment, many samples",UPN2_082,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1265,119,1406,"0,0846372688",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"25,83","14,44"
"low bq, bad alignment, many samples",UPN2_083,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1692,154,1878,"0,0820021299",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"25,77","14,26"
"low bq, bad alignment, many samples",UPN2_084,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1702,159,1901,"0,0836401894",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"25,97","14,42"
"low bq, bad alignment, many samples",UPN2_085,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),824,70,910,"0,0769230769",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,26,"14,64"
"low bq, bad alignment, many samples",UPN2_087,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),1201,94,1329,"0,0707298721",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"25,81","14,89"
"low bq, bad alignment, many samples",UPN2_088,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),924,61,996,"0,0612449799",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"25,31","14,66"
"low bq, bad alignment, many samples",UPN2_094,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),13574,335,14003,"0,023923445",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"26,14","14,49"
"low bq, bad alignment, many samples",UPN2_095,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),11680,302,12057,"0,0250476901",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"26,2","14,55"
"low bq, bad alignment, many samples",UPN2_096,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),13623,365,14107,"0,0258736797",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"26,21","14,4"
"low bq, bad alignment, many samples",UPN2_097,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),14366,403,14872,"0,0270979021",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"26,21","14,3"
"low bq, bad alignment, many samples",UPN2_098,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),11398,279,11752,"0,0237406399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"26,18","14,29"
"low bq, bad alignment, many samples",UPN2_099,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),6933,175,7160,"0,0244413408",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"26,18","14,18"
"low bq, bad alignment, many samples",UPN2_100,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),12565,290,12942,"0,022407665",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"26,16","14,39"
"low bq, bad alignment, many samples",UPN2_101,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),10439,290,10793,"0,0268692671",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"26,15","14,18"
"low bq, bad alignment, many samples",UPN2_102,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),11641,345,12075,"0,0285714286",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"26,16","14,23"
"low bq, bad alignment, many samples",UPN2_103,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),11461,312,11834,"0,0263647118",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"26,16","14,54"
"low bq, bad alignment, many samples",UPN2_104,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),14627,384,15113,"0,0254085886",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"26,17","14,12"
"low bq, bad alignment, many samples",UPN2_105,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),11275,319,11658,"0,0273631841",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"26,12","14,44"
"low bq, bad alignment, many samples",UPN2_106,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),21309,540,21999,"0,0245465703",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"26,27","14,49"
"low bq, bad alignment, many samples",UPN2_107,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),20901,546,21566,"0,0253176296",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"26,29","14,32"
"low bq, bad alignment, many samples",UPN2_108,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),19079,473,19704,"0,0240052781",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"26,36","14,15"
"low bq, bad alignment, many samples",UPN2_109,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),17060,507,17681,"0,0286748487",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"26,14","14,49"
"low bq, bad alignment, many samples",UPN2_110,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),21642,608,22375,"0,0271731844",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"26,24","14,27"
"low bq, bad alignment",UPN2_111,21,36164869,A,C,missense_variant(MODERATE|MISSENSE|Ttc/Gtc|p.Phe336Val/c.1006T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|9|C),14264,393,14758,"0,0266296246",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,47",Deleterious,103,Tolerated,"26,29","14,67"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,21,36164869,A,G,missense_variant(MODERATE|MISSENSE|Ttc/Ctc|p.Phe336Leu/c.1006T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3785,51,4200,"0,0121428571",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,85",Deleterious,52,Tolerated,"25,73","26,61"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,21,36164869,A,G,missense_variant(MODERATE|MISSENSE|Ttc/Ctc|p.Phe336Leu/c.1006T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2140,27,2367,"0,0114068441",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,85",Deleterious,52,Tolerated,"25,55","21,07"
"inspected, many artifacts, bad alignment",UPN2_084,21,36164869,A,G,missense_variant(MODERATE|MISSENSE|Ttc/Ctc|p.Phe336Leu/c.1006T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1702,29,1901,"0,0152551289",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,85",Deleterious,"0,052",Tolerated,"25,97","26,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_041,21,36164869,A,T,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe336Ile/c.1006T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),59284,658,60659,"0,0108475247",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,"8,30E-006",NO,NO,"-3,82",Deleterious,1,Damaging,"26,74","17,86"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,21,36164869,A,T,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe336Ile/c.1006T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),36890,384,37716,"0,0101813554",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,"8,30E-006",NO,NO,"-3,82",Deleterious,1,Damaging,"26,78","17,06"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_044,21,36164869,A,T,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe336Ile/c.1006T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),3734,42,3809,"0,0110265161",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,"8,30E-006",NO,NO,"-3,82",Deleterious,1,Damaging,"26,73",16
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_048,21,36164869,A,T,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe336Ile/c.1006T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),37060,389,37858,"0,0102752391",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,"8,30E-006",NO,NO,"-3,82",Deleterious,1,Damaging,"26,71","17,66"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,21,36164869,A,T,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe336Ile/c.1006T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),23153,248,23658,"0,010482712",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,"8,30E-006",NO,NO,"-3,82",Deleterious,1,Damaging,"26,7","17,24"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,21,36164869,A,T,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe336Ile/c.1006T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),23601,242,24105,"0,0100394109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,"8,30E-006",NO,NO,"-3,82",Deleterious,1,Damaging,"26,64","17,25"
"low bq, bad alignment, low freq, many artifacts",UPN2_071,21,36164869,A,T,missense_variant(MODERATE|MISSENSE|Ttc/Atc|p.Phe336Ile/c.1006T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),6520,72,7198,"0,0100027785",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,"8,30E-006",NO,NO,"-3,82",Deleterious,1,Damaging,"25,65","17,75"
"low bq, bad alignment, low freq, many artifacts",UPN2_072,21,36164870,C,G,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln335His/c.1005G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),5086,53,5144,"0,0103032659",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,6",Deleterious,92,Tolerated,"26,82",14
"low bq, low freq, many artifacts, many samples",UPN2_075,21,36164871,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln335Pro/c.1004A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1876,20,1903,"0,0105097215",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,72",Deleterious,7,Damaging,"32,76","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_078,21,36164871,T,G,missense_variant(MODERATE|MISSENSE|cAg/cCg|p.Gln335Pro/c.1004A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1481,20,1514,"0,0132100396",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,72",Deleterious,7,Damaging,"33,25","16,75"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,21,36164880,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp332Ala/c.995A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2113,33,2149,"0,0153559795",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,21",Deleterious,49,Damaging,"25,49","14,21"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,21,36164880,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp332Ala/c.995A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1176,26,1206,"0,0215588723",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,21",Deleterious,49,Damaging,"25,59",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,21,36164880,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp332Ala/c.995A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3597,39,3658,"0,0106615637",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,21",Deleterious,49,Damaging,"25,63","15,1"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,21,36164880,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp332Ala/c.995A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2587,32,2629,"0,0121719285",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,21",Deleterious,49,Damaging,"25,88","14,22"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_075,21,36164880,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp332Ala/c.995A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),1781,27,1811,"0,0149088901",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,21",Deleterious,49,Damaging,"25,58",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,21,36164880,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp332Ala/c.995A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),2406,33,2449,"0,0134748877",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,21",Deleterious,49,Damaging,"25,89",14
"low bq, bad alignment, low freq, many artifacts",UPN2_081,21,36164880,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp332Ala/c.995A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|9|G),3958,56,4035,"0,0138785626",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,21",Deleterious,49,Damaging,"25,74","14,23"
"inspected, many artifacts",UPN2_044,21,36164895,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu327Gln/c.980T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),1869,27,1905,"0,0141732283",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,18",Deleterious,0,Damaging,"34,67","26,89"
"inspected, many artifacts",UPN2_056,21,36164895,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu327Gln/c.980T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|9|T),5923,92,6051,"0,0152040985",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,18",Deleterious,0,Damaging,"34,54","26,23"
"inspected, many artifacts",UPN2_044,21,36171615,A,G,missense_variant(MODERATE|MISSENSE|cTt/cCt|p.Leu317Pro/c.950T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|8|G),2481,33,2521,"0,0130900436",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,"0,004",Damaging,"35,19","35,21"
"low freq, many artifacts",UPN2_011,21,36171627,A,G,missense_variant(MODERATE|MISSENSE|cTc/cCc|p.Leu313Pro/c.938T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|8|G),13895,177,14094,"0,0125585355",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,9",Neutral,"0,007",Damaging,"35,17","34,89"
"inspected, many artifacts",UPN2_056,21,36171652,C,T,missense_variant(MODERATE|MISSENSE|Gga/Aga|p.Gly305Arg/c.913G>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),788,20,808,"0,0247524752",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,05",Neutral,"0,01",Damaging,"33,62","32,85"
"low bq, low freq, many artifacts, many samples",UPN2_042,21,36171660,A,T,missense_variant(MODERATE|MISSENSE|aTt/aAt|p.Ile302Asn/c.905T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),14186,147,14434,"0,0101842871",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,4,Damaging,"30,91","16,15"
"low bq, low freq, many artifacts, many samples",UPN2_044,21,36171660,A,T,missense_variant(MODERATE|MISSENSE|aTt/aAt|p.Ile302Asn/c.905T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),4921,51,4984,"0,0102327448",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,4,Damaging,"30,69","16,65"
"low bq, low freq, many artifacts, many samples",UPN2_045,21,36171660,A,T,missense_variant(MODERATE|MISSENSE|aTt/aAt|p.Ile302Asn/c.905T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),22173,247,22536,"0,0109602414",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,4,Damaging,"31,01","15,57"
"low bq, low freq, many artifacts, many samples",UPN2_047,21,36171660,A,T,missense_variant(MODERATE|MISSENSE|aTt/aAt|p.Ile302Asn/c.905T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),13057,149,13295,"0,0112072208",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,4,Damaging,"31,1","16,81"
"low bq, low freq, many artifacts, many samples",UPN2_049,21,36171660,A,T,missense_variant(MODERATE|MISSENSE|aTt/aAt|p.Ile302Asn/c.905T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),8565,92,8691,"0,0105856633",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,4,Damaging,"30,88","16,35"
"low bq, low freq, many artifacts, many samples",UPN2_050,21,36171660,A,T,missense_variant(MODERATE|MISSENSE|aTt/aAt|p.Ile302Asn/c.905T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),19791,234,20159,"0,0116077186",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,4,Damaging,"30,91","16,56"
"low bq, low freq, many artifacts, many samples",UPN2_051,21,36171660,A,T,missense_variant(MODERATE|MISSENSE|aTt/aAt|p.Ile302Asn/c.905T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),20717,237,21073,"0,0112466189",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,4,Damaging,"30,91","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_053,21,36171660,A,T,missense_variant(MODERATE|MISSENSE|aTt/aAt|p.Ile302Asn/c.905T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),27720,320,28231,"0,0113350572",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,4,Damaging,"30,92","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_054,21,36171660,A,T,missense_variant(MODERATE|MISSENSE|aTt/aAt|p.Ile302Asn/c.905T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),17318,191,17613,"0,0108442628",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,4,Damaging,"31,01","15,74"
"low bq, low freq, many artifacts, many samples",UPN2_055,21,36171660,A,T,missense_variant(MODERATE|MISSENSE|aTt/aAt|p.Ile302Asn/c.905T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),25478,331,25949,"0,0127557902",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,4,Damaging,"30,95","17,2"
"low bq, low freq, many artifacts",UPN2_057,21,36171660,A,T,missense_variant(MODERATE|MISSENSE|aTt/aAt|p.Ile302Asn/c.905T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),20948,220,21327,"0,0103155624",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,4,Damaging,"30,93","16,1"
"inspected, many artifacts",UPN2_044,21,36171671,TG,T,frameshift_variant(HIGH||cca/|p.Pro298fs/c.893delC|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),4912,63,4987,"0,0126328454",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,63",NA
"low bq, low freq, many artifacts, many samples",UPN2_043,21,36171678,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val296Glu/c.887T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),17180,177,17446,"0,0101455921",0,0,0,0,1,0,0,0,1,NO,NO,COSM5097437,large_intestine,1,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,5,Damaging,"30,43","18,93"
"low bq, low freq, many artifacts, many samples",UPN2_050,21,36171678,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val296Glu/c.887T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),19865,225,20183,"0,0111479958",0,0,0,0,1,0,0,0,1,NO,NO,COSM5097437,large_intestine,1,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,5,Damaging,"30,18","19,83"
"low bq, low freq, many artifacts, many samples",UPN2_052,21,36171678,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val296Glu/c.887T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),20913,224,21242,"0,0105451464",0,0,0,0,1,0,0,0,1,NO,NO,COSM5097437,large_intestine,1,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,5,Damaging,"30,34","21,21"
"low bq, low freq, many artifacts, many samples",UPN2_057,21,36171678,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val296Glu/c.887T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),21009,217,21350,"0,0101639344",0,0,0,0,1,0,0,0,1,NO,NO,COSM5097437,large_intestine,1,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,5,Damaging,"30,2","18,28"
"low bq, low freq, many artifacts, many samples",UPN2_058,21,36171678,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val296Glu/c.887T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),20390,211,20764,"0,0101618185",0,0,0,0,1,0,0,0,1,NO,NO,COSM5097437,large_intestine,1,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,5,Damaging,"30,27","19,65"
"low bq, low freq, many artifacts",UPN2_079,21,36171678,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val296Glu/c.887T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),7127,86,7247,"0,0118669794",0,0,0,0,1,0,0,0,1,NO,NO,COSM5097437,large_intestine,1,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,5,Damaging,"29,11","20,21"
"low freq, many artifacts",UPN2_044,21,36171682,A,T,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser295Thr/c.883T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),4926,51,4992,"0,0102163462",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,196,Tolerated,"33,18","27,76"
"low freq, many artifacts",UPN2_044,21,36171688,A,T,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser293Thr/c.877T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),4903,50,4993,"0,0100140196",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,42",Neutral,381,Tolerated,"32,87","27,32"
"low bq, low freq, many artifacts, many samples",UPN2_061,21,36171705,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr287Ser/c.860A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|8|G),10865,110,10995,"0,0100045475",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,24",Deleterious,4,Damaging,"29,66","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_067,21,36171705,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr287Ser/c.860A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|8|G),14213,149,14397,"0,0103493783",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,24",Deleterious,4,Damaging,"29,82","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_068,21,36171705,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr287Ser/c.860A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|8|G),12118,129,12292,"0,0104946307",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,24",Deleterious,4,Damaging,"29,58","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_069,21,36171705,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr287Ser/c.860A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|8|G),14467,149,14654,"0,0101678723",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,24",Deleterious,4,Damaging,"29,66","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_072,21,36171705,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr287Ser/c.860A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|8|G),5480,64,5564,"0,0115025162",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,24",Deleterious,4,Damaging,"29,48","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_078,21,36171705,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr287Ser/c.860A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|8|G),10916,121,11078,"0,0109225492",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,24",Deleterious,4,Damaging,"29,6","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_084,21,36171705,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr287Ser/c.860A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|8|G),11554,121,11705,"0,0103374626",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,24",Deleterious,4,Damaging,"29,6","14,22"
"low bq, low freq, many artifacts",UPN2_085,21,36171705,T,G,missense_variant(MODERATE|MISSENSE|tAc/tCc|p.Tyr287Ser/c.860A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|8|G),12089,135,12258,"0,0110132159",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,24",Deleterious,4,Damaging,"29,61","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_001,21,36171706,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr287Asn/c.859T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),11056,113,11196,"0,0100928903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,99",Deleterious,21,Damaging,"32,86","16,55"
"low bq, low freq, many artifacts, many samples",UPN2_042,21,36171706,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr287Asn/c.859T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),14225,185,14471,"0,0127841891",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,99",Deleterious,21,Damaging,"32,44","17,6"
"low bq, low freq, many artifacts, many samples",UPN2_043,21,36171706,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr287Asn/c.859T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),17156,247,17467,"0,0141409515",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,99",Deleterious,21,Damaging,"32,52","17,64"
"low bq, low freq, many artifacts, many samples",UPN2_044,21,36171706,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr287Asn/c.859T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),4916,58,4996,"0,0116092874",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,99",Deleterious,21,Damaging,"32,32","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_045,21,36171706,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr287Asn/c.859T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),22248,282,22597,"0,0124795327",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,99",Deleterious,21,Damaging,"32,46","17,32"
"low bq, low freq, many artifacts, many samples",UPN2_046,21,36171706,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr287Asn/c.859T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),18607,259,18904,"0,0137008041",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,99",Deleterious,21,Damaging,"32,38","16,47"
"low bq, low freq, many artifacts, many samples",UPN2_047,21,36171706,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr287Asn/c.859T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),13136,168,13322,"0,0126107191",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,99",Deleterious,21,Damaging,"32,39","15,3"
"low bq, low freq, many artifacts, many samples",UPN2_006,21,36171706,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr287Asn/c.859T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),8318,98,8426,"0,011630667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,99",Deleterious,21,Damaging,"32,92","15,84"
"low bq, low freq, many artifacts, many samples",UPN2_049,21,36171706,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr287Asn/c.859T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),8599,95,8709,"0,0109082558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,99",Deleterious,21,Damaging,"32,24","15,77"
"low bq, low freq, many artifacts, many samples",UPN2_050,21,36171706,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr287Asn/c.859T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),19875,265,20201,"0,0131181625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,99",Deleterious,21,Damaging,"32,32","15,3"
"low bq, low freq, many artifacts, many samples",UPN2_051,21,36171706,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr287Asn/c.859T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),20742,292,21120,"0,0138257576",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,99",Deleterious,21,Damaging,"32,43","15,59"
"low bq, low freq, many artifacts, many samples",UPN2_052,21,36171706,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr287Asn/c.859T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),20906,281,21258,"0,013218553",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,99",Deleterious,21,Damaging,"32,41","17,16"
"low bq, low freq, many artifacts, many samples",UPN2_053,21,36171706,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr287Asn/c.859T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),27838,363,28290,"0,0128313892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,99",Deleterious,21,Damaging,"32,38","15,8"
"low bq, low freq, many artifacts, many samples",UPN2_054,21,36171706,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr287Asn/c.859T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),17393,217,17654,"0,0122918319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,99",Deleterious,21,Damaging,"32,43","15,74"
"low bq, low freq, many artifacts, many samples",UPN2_007,21,36171706,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr287Asn/c.859T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),31351,321,31764,"0,0101057801",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,99",Deleterious,21,Damaging,"32,83","15,53"
"low bq, low freq, many artifacts, many samples",UPN2_008,21,36171706,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr287Asn/c.859T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),44138,501,44721,"0,0112027906",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,99",Deleterious,21,Damaging,"32,96","16,11"
"low bq, low freq, many artifacts, many samples",UPN2_009,21,36171706,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr287Asn/c.859T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),37012,412,37470,"0,010995463",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,99",Deleterious,21,Damaging,"32,89","16,39"
"low bq, low freq, many artifacts, many samples",UPN2_011,21,36171706,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr287Asn/c.859T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),27351,305,27702,"0,0110100354",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,99",Deleterious,21,Damaging,"32,93","16,51"
"low bq, low freq, many artifacts, many samples",UPN2_055,21,36171706,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr287Asn/c.859T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),25555,337,25987,"0,0129680225",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,99",Deleterious,21,Damaging,"32,37","15,93"
"low bq, low freq, many artifacts, many samples",UPN2_057,21,36171706,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr287Asn/c.859T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),20980,330,21373,"0,0154400412",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,99",Deleterious,21,Damaging,"32,43","16,97"
"low bq, low freq, many artifacts, many samples",UPN2_058,21,36171706,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr287Asn/c.859T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),20410,329,20775,"0,0158363418",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,99",Deleterious,21,Damaging,"32,47","18,88"
"low bq, low freq, many artifacts",UPN2_012,21,36171706,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr287Asn/c.859T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),14023,157,14220,"0,0110407876",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,99",Deleterious,21,Damaging,"32,95","17,76"
"low bq, low freq, many artifacts, many samples",UPN2_065,21,36171707,T,G,missense_variant(MODERATE|MISSENSE|caA/caC|p.Gln286His/c.858A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|8|G),6198,67,6285,"0,0106603023",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,48",Neutral,119,Tolerated,"29,99","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_072,21,36171707,T,G,missense_variant(MODERATE|MISSENSE|caA/caC|p.Gln286His/c.858A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|8|G),5486,57,5566,"0,0102407474",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,48",Neutral,119,Tolerated,"29,6","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_059,21,36171715,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser284Ala/c.850T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|8|C),3419,36,3465,"0,0103896104",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,68",Neutral,12,Damaging,"29,05","14,19"
"low bq, low freq, many artifacts, many samples",UPN2_064,21,36171715,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser284Ala/c.850T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|8|C),2877,30,2925,"0,0102564103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,68",Neutral,12,Damaging,"29,04",14
"low bq, low freq, many artifacts, many samples",UPN2_070,21,36171715,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser284Ala/c.850T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|8|C),8517,112,8685,"0,0128957974",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,68",Neutral,12,Damaging,"28,79","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_071,21,36171715,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser284Ala/c.850T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|8|C),7109,78,7224,"0,0107973422",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,68",Neutral,12,Damaging,"28,79","14,17"
"low bq, low freq, many artifacts",UPN2_081,21,36171715,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser284Ala/c.850T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|8|C),5237,56,5350,"0,0104672897",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,68",Neutral,12,Damaging,"28,78","15,34"
"low bq, low freq, many artifacts, many samples",UPN2_018,21,36171719,A,T,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp282Glu/c.846T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),7419,84,7525,"0,0111627907",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,101,Tolerated,"33,22","17,82"
"low bq, low freq, many artifacts, many samples",UPN2_042,21,36171719,A,T,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp282Glu/c.846T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),7414,80,7526,"0,0106298166",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,101,Tolerated,"32,42","17,74"
"low bq, low freq, many artifacts, many samples",UPN2_043,21,36171719,A,T,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp282Glu/c.846T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),8937,104,9083,"0,0114499615",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,101,Tolerated,"32,71","18,13"
"low bq, low freq, many artifacts, many samples",UPN2_029,21,36171719,A,T,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp282Glu/c.846T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),9136,93,9269,"0,0100334448",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,101,Tolerated,"33,3","19,95"
"low bq, low freq, many artifacts, many samples",UPN2_005,21,36171719,A,T,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp282Glu/c.846T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),2317,24,2351,"0,0102084219",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,101,Tolerated,"32,85","15,46"
"low bq, low freq, many artifacts, many samples",UPN2_045,21,36171719,A,T,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp282Glu/c.846T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),11423,150,11638,"0,0128888125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,101,Tolerated,"32,53","17,48"
"low bq, low freq, many artifacts, many samples",UPN2_034,21,36171719,A,T,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp282Glu/c.846T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),3113,32,3159,"0,0101297879",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,101,Tolerated,"32,91","18,81"
"low bq, low freq, many artifacts, many samples",UPN2_006,21,36171719,A,T,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp282Glu/c.846T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),4323,50,4383,"0,0114077116",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,101,Tolerated,"32,97","17,06"
"low bq, low freq, many artifacts, many samples",UPN2_050,21,36171719,A,T,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp282Glu/c.846T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),10260,117,10435,"0,0112122664",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,101,Tolerated,"32,38","17,33"
"low bq, low freq, many artifacts, many samples",UPN2_051,21,36171719,A,T,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp282Glu/c.846T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),10842,122,11008,"0,0110828488",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,101,Tolerated,"32,41","17,61"
"low bq, low freq, many artifacts, many samples",UPN2_052,21,36171719,A,T,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp282Glu/c.846T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),10915,117,11080,"0,0105595668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,101,Tolerated,"32,4","16,05"
"low bq, low freq, many artifacts, many samples",UPN2_053,21,36171719,A,T,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp282Glu/c.846T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),14539,151,14749,"0,0102379822",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,101,Tolerated,"32,38","17,52"
"low bq, low freq, many artifacts, many samples",UPN2_054,21,36171719,A,T,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp282Glu/c.846T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),9061,93,9214,"0,0100933362",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,101,Tolerated,"32,42","16,01"
"low bq, low freq, many artifacts, many samples",UPN2_011,21,36171719,A,T,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp282Glu/c.846T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),14325,159,14535,"0,0109391125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,101,Tolerated,"32,96","16,55"
"low bq, low freq, many artifacts, many samples",UPN2_055,21,36171719,A,T,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp282Glu/c.846T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),13307,164,13524,"0,0121265898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,101,Tolerated,"32,48","16,84"
"low bq, low freq, many artifacts, many samples",UPN2_057,21,36171719,A,T,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp282Glu/c.846T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),10999,129,11169,"0,0115498254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,101,Tolerated,"32,53","18,57"
"low bq, low freq, many artifacts, many samples",UPN2_058,21,36171719,A,T,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp282Glu/c.846T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),10663,126,10836,"0,011627907",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,101,Tolerated,"32,62","16,87"
"low bq, low freq, many artifacts, many samples",UPN2_013,21,36171719,A,T,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp282Glu/c.846T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),4378,48,4441,"0,0108083765",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,101,Tolerated,"33,01","16,02"
"inspected, many artifacts",UPN2_092,21,36171719,A,T,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp282Glu/c.846T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),2855,40,2901,"0,0137883488",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,"0,101",Tolerated,"33,97","26,67"
"low bq, low freq, many artifacts",UPN2_072,21,36171719,A,T,missense_variant(MODERATE|MISSENSE|gaT/gaA|p.Asp282Glu/c.846T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),2859,30,2909,"0,0103128223",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,81",Neutral,101,Tolerated,"33,17","18,13"
"low bq, low freq, many artifacts",UPN2_006,21,36171724,A,T,missense_variant(MODERATE|MISSENSE|Tac/Aac|p.Tyr281Asn/c.841T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),4129,42,4180,"0,0100478469",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,52",Deleterious,1,Damaging,"33,63","17,48"
"low bq, low freq, many artifacts, many samples",UPN2_042,21,36171730,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp279Arg/c.835T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),7057,88,7175,"0,0122648084",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,77",Deleterious,251,Tolerated,"33,52","17,99"
"low bq, low freq, many artifacts, many samples",UPN2_043,21,36171730,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp279Arg/c.835T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),8565,92,8679,"0,0106002996",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,77",Deleterious,251,Tolerated,"33,82","17,49"
"low bq, low freq, many artifacts, many samples",UPN2_044,21,36171730,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp279Arg/c.835T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),2439,36,2482,"0,0145044319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,77",Deleterious,251,Tolerated,"33,56","17,42"
"low bq, low freq, many artifacts, many samples",UPN2_046,21,36171730,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp279Arg/c.835T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),9251,98,9382,"0,010445534",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,77",Deleterious,251,Tolerated,"33,63","19,72"
"low bq, low freq, many artifacts, many samples",UPN2_049,21,36171730,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp279Arg/c.835T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),4260,47,4323,"0,0108720796",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,77",Deleterious,251,Tolerated,"33,68","19,45"
"low bq, low freq, many artifacts, many samples",UPN2_050,21,36171730,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp279Arg/c.835T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),9865,115,10020,"0,0114770459",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,77",Deleterious,251,Tolerated,"33,54","16,2"
"low bq, low freq, many artifacts, many samples",UPN2_051,21,36171730,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp279Arg/c.835T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),10324,121,10472,"0,0115546218",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,77",Deleterious,251,Tolerated,"33,61","17,69"
"low bq, low freq, many artifacts, many samples",UPN2_054,21,36171730,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp279Arg/c.835T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),8625,104,8768,"0,0118613139",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,77",Deleterious,251,Tolerated,"33,65","18,33"
"low bq, low freq, many artifacts",UPN2_055,21,36171730,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp279Arg/c.835T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),12685,144,12877,"0,0111827289",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,77",Deleterious,251,Tolerated,"33,62","16,84"
"low bq, low freq, many artifacts, many samples",UPN2_042,21,36171739,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser276Thr/c.826T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),7087,73,7188,"0,0101558152",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,35,Damaging,"34,31","19,27"
"low bq, low freq, many artifacts, many samples",UPN2_043,21,36171739,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser276Thr/c.826T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),8560,88,8685,"0,0101324122",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,35,Damaging,"34,47","18,06"
"low bq, low freq, many artifacts, many samples",UPN2_057,21,36171739,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser276Thr/c.826T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|8|T),10425,107,10602,"0,0100924354",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,64",Neutral,35,Damaging,"34,34","17,34"
"inspected, many artifacts",UPN2_090,21,36206707,C,T,missense_variant(MODERATE|MISSENSE|Gat/Aat|p.Asp269Asn/c.805G>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),1103,20,1125,"0,0177777778",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,4",Neutral,"0,083",Tolerated,"34,54",36
"inspected, many artifacts",UPN2_028,21,36206715,T,C,missense_variant(MODERATE|MISSENSE|cAg/cGg|p.Gln266Arg/c.797A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1756,21,1783,"0,0117779024",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,44",Neutral,"0,043",Damaging,"35,11","34,76"
"inspected, many artifacts",UPN2_044,21,36206721,T,A,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln264Leu/c.791A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|7|A),1200,20,1225,"0,0163265306",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,"0,026",Damaging,"34,64","34,9"
"inspected, many artifacts",UPN2_041,21,36206732,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn260Lys/c.780C>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3730,53,3787,"0,0139952469",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,11",Deleterious,"0,011",Damaging,"34,79","33,04"
"inspected, many artifacts",UPN2_054,21,36206737,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe259Leu/c.775T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2750,31,2790,"0,0111111111",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,05",Deleterious,"0,084",Tolerated,"34,73","34,19"
"inspected, many artifacts",UPN2_041,21,36206749,G,T,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His255Asn/c.763C>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3729,40,3783,"0,0105736188",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,37",Neutral,"0,439",Tolerated,"34,63","33,78"
"inspected, many artifacts",UPN2_083,21,36206753,CA,C,frameshift_variant(HIGH||ctg/|p.Leu253fs/c.758delT|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1608,22,1645,"0,0133738602",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,03",NA
"inspected, many artifacts",UPN2_044,21,36206754,A,G,missense_variant(MODERATE|MISSENSE|cTg/cCg|p.Leu253Pro/c.758T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1196,27,1225,"0,0220408163",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,04",Deleterious,"0,026",Damaging,"34,52","33,59"
"low bq, many samples",UPN2_001,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1420,94,1617,"0,0581323438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"29,42",14
"low bq, many samples",UPN2_014,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),3316,137,3635,"0,0376891334",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,61","14,09"
"low bq, many samples",UPN2_015,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),5121,197,5592,"0,0352288984",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"29,27","14,24"
"low bq, many samples",UPN2_016,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2378,132,2657,"0,0496800903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,93",14
"low bq, many samples",UPN2_017,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1643,68,1804,"0,0376940133",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,84",14
"low bq, many samples",UPN2_018,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2948,140,3261,"0,0429316161",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,83","14,09"
"low bq, many samples",UPN2_019,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),3034,113,3300,"0,0342424242",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"29,06",14
"low bq, many samples",UPN2_020,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2249,101,2491,"0,0405459655",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"29,13",14
"low bq, many samples",UPN2_021,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2460,101,2699,"0,0374212671",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"29,28",14
"low bq, many samples",UPN2_002,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2016,131,2267,"0,0577856198",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"29,08","14,17"
"low bq, many samples",UPN2_003,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),398,24,439,"0,0546697039",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"29,56",14
"low bq, many samples",UPN2_022,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),3026,118,3393,"0,0347774831",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,54",14
"low bq, many samples",UPN2_023,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),3872,209,4323,"0,048346056",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,79","14,06"
"low bq, many samples",UPN2_041,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),5661,207,6287,"0,0329250835",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,62","14,11"
"low bq, many samples",UPN2_024,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1823,82,2007,"0,0408570005",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,58","14,16"
"low bq, many samples",UPN2_025,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),3658,130,3973,"0,0327208658",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"29,61",14
"low bq, many samples",UPN2_026,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),4459,206,4899,"0,0420493978",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,77",14
"low bq, many samples",UPN2_027,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),4022,198,4462,"0,0443747199",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,8","14,2"
"low bq, many samples",UPN2_089,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),3529,107,3723,"0,0287402632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,76","14,12"
"low bq, many samples",UPN2_042,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),7548,390,8281,"0,0470957614",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,63","14,16"
"low bq, many samples",UPN2_028,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2870,113,3136,"0,0360331633",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"29,28","14,31"
"low bq, many samples",UPN2_043,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),4631,207,5061,"0,0409010077",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,74","14,07"
"low bq, many samples",UPN2_044,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1968,78,2142,"0,0364145658",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,51",14
"low bq, many samples",UPN2_029,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),3126,166,3476,"0,0477560414",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"29,01","14,24"
"low bq, many samples",UPN2_030,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),3851,136,4197,"0,0324040982",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"29,06","14,65"
"low bq, many samples",UPN2_031,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2817,122,3181,"0,0383527193",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,61","14,36"
"low bq, many samples",UPN2_005,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),696,37,773,"0,0478654592",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"29,33",14
"low bq, many samples",UPN2_045,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),5296,245,5804,"0,0422122674",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,5","14,24"
"low bq, many samples",UPN2_032,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1342,53,1454,"0,0364511692",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,52",14
"low bq, many samples",UPN2_046,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),6311,237,6848,"0,0346086449",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,29,"14,06"
"low bq, many samples",UPN2_033,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2961,127,3273,"0,038802322",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,94",14
"low bq, many samples",UPN2_034,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),972,48,1068,"0,0449438202",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"29,02",14
"low bq, many samples",UPN2_047,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),9058,406,9888,"0,0410598706",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,68","14,15"
"low bq, many samples",UPN2_048,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),6605,230,7130,"0,0322580645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,88","14,25"
"low bq, many samples",UPN2_035,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),4571,200,5151,"0,0388274122",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,67","14,11"
"low bq, many samples",UPN2_036,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),3691,179,4095,"0,0437118437",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,91","14,04"
"low bq, many samples",UPN2_006,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1412,71,1579,"0,0449651678",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"29,1","14,31"
"low bq, many samples",UPN2_049,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),5905,277,6555,"0,0422578185",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,67","14,13"
"low bq, many samples",UPN2_050,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),6044,301,6659,"0,0452019823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,67","14,15"
"low bq, many samples",UPN2_037,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),6278,276,6890,"0,0400580552",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,95","14,05"
"low bq, many samples",UPN2_051,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),6179,300,6780,"0,0442477876",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,53","14,21"
"low bq, many samples",UPN2_052,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),5065,249,5533,"0,045002711",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,55","14,2"
"low bq, many samples",UPN2_038,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),6698,357,7456,"0,0478809013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,67","14,42"
"low bq, many samples",UPN2_039,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),6933,298,7604,"0,0391899001",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"29,22","14,02"
"low bq, many samples",UPN2_053,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),7764,392,8535,"0,0459285296",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,47","14,12"
"low bq, many samples",UPN2_054,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),4466,182,4836,"0,0376344086",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,93","14,5"
"low bq, many samples",UPN2_007,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),4812,247,5390,"0,045825603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"29,18","14,13"
"low bq, many samples",UPN2_008,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),7520,401,8409,"0,047687002",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"29,12","14,15"
"low bq, many samples",UPN2_009,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),5904,346,6657,"0,0519753643",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,29,"14,09"
"low bq, many samples",UPN2_010,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),3142,127,3463,"0,0366734046",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"29,08","14,17"
"low bq, many samples",UPN2_011,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),3660,222,4142,"0,053597296",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"29,31","14,18"
"low bq, many samples",UPN2_055,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),7495,367,8231,"0,0445875349",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,6","14,2"
"low bq, many samples",UPN2_056,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2864,134,3126,"0,0428662828",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,92","14,49"
"low bq, many samples",UPN2_090,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1924,66,2043,"0,0323054332",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,74","14,2"
"low bq, many samples",UPN2_057,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),4962,237,5440,"0,0435661765",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,68","14,19"
"low bq, many samples",UPN2_058,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),4325,202,4749,"0,0425352706",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,65","14,06"
"low bq, many samples",UPN2_059,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1382,42,1482,"0,028340081",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"27,79","14,31"
"low bq, many samples",UPN2_012,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1886,87,2163,"0,040221914",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"29,28",14
"low bq, many samples",UPN2_060,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2966,124,3173,"0,0390797353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,38",14
"low bq, many samples",UPN2_040,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),6906,356,7698,"0,0462457781",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,99","14,25"
"low bq, many samples",UPN2_013,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1278,76,1447,"0,0525224603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"29,53",14
"low bq, low freq, many artifacts, many samples",UPN2_091,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2638,59,2793,"0,0211242392",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"27,55",14
"low bq, many samples",UPN2_092,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1288,43,1368,"0,0314327485",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,84","14,42"
"low bq, many samples",UPN2_093,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1861,56,1960,"0,0285714286",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,52","14,23"
"low bq, many samples",UPN2_061,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),3127,134,3340,"0,0401197605",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,31","14,34"
"low bq, many samples",UPN2_062,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),4157,144,4416,"0,0326086957",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,59","14,18"
"low bq, many samples",UPN2_063,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2907,104,3082,"0,0337443219",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,46","14,33"
"low bq, many samples",UPN2_064,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2516,97,2680,"0,0361940299",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,39","14,26"
"low bq, many samples",UPN2_066,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),606,27,651,"0,0414746544",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,46",14
"low bq, many samples",UPN2_067,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1036,35,1101,"0,0317892825",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,58","14,37"
"low bq, many samples",UPN2_068,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1635,77,1765,"0,0436260623",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,85","14,57"
"low bq, many samples",UPN2_069,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2383,101,2555,"0,0395303327",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,16","14,48"
"low bq, many samples",UPN2_070,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1583,68,1706,"0,03985932",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,36",14
"low bq, many samples",UPN2_071,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),4083,174,4375,"0,0397714286",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,47","14,45"
"low bq, many samples",UPN2_072,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),4953,169,5296,"0,0319108761",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,5","14,29"
"low bq, many samples",UPN2_073,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2383,79,2542,"0,0310778914",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"27,82","14,67"
"low bq, many samples",UPN2_074,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1088,49,1178,"0,0415959253",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,57","14,71"
"low bq, many samples",UPN2_075,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),4097,157,4377,"0,0358693169",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,34","14,56"
"low bq, many samples",UPN2_076,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2447,109,2619,"0,0416189385",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,34","14,24"
"low bq, many samples",UPN2_077,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2139,87,2290,"0,0379912664",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,38","15,38"
"low bq, many samples",UPN2_078,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),3239,107,3430,"0,0311953353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,54","14,3"
"low bq, many samples",UPN2_079,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1663,74,1790,"0,0413407821",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,34","14,18"
"low bq, many samples",UPN2_080,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),5248,171,5574,"0,0306781485",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,55","14,8"
"low bq, many samples",UPN2_081,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),6781,224,7246,"0,0309136075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"27,7","14,46"
"low bq, many samples",UPN2_082,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2052,84,2188,"0,0383912249",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,12","14,9"
"low bq, many samples",UPN2_083,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2835,126,3039,"0,0414610069",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,14","14,53"
"low bq, many samples",UPN2_084,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2665,111,2848,"0,0389747191",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,26","14,56"
"low bq, many samples",UPN2_085,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1854,73,1984,"0,0367943548",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,34","14,9"
"low bq, many samples",UPN2_086,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1037,32,1091,"0,0293308891",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,6",14
"low bq, many samples",UPN2_087,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2244,83,2384,"0,0348154362",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,4","14,31"
"low bq, many samples",UPN2_088,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1734,62,1854,"0,0334412082",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"27,99","14,32"
"low bq, many samples",UPN2_094,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),3817,127,4037,"0,0314590042",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,43",14
"low bq, many samples",UPN2_095,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),4015,109,4203,"0,0259338568",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"29,24","14,18"
"low bq, many samples",UPN2_096,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),3977,140,4207,"0,0332778702",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,95","14,05"
"low bq, many samples",UPN2_097,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),4488,127,4755,"0,0267087277",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"29,04","14,28"
"low bq, many samples",UPN2_098,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),3196,79,3375,"0,0234074074",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"27,5",14
"low bq, many samples",UPN2_099,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1932,60,2045,"0,0293398533",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,44",14
"low bq, many samples",UPN2_100,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),4146,137,4390,"0,0312072893",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,32",14
"low bq, many samples",UPN2_101,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),3617,115,3809,"0,0301916514",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,79",14
"low bq, many samples",UPN2_102,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),3308,126,3502,"0,0359794403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,56",14
"low bq, many samples",UPN2_103,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),4213,121,4431,"0,0273076055",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"29,17","14,11"
"low bq, many samples",UPN2_104,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),4409,186,4691,"0,0396503944",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,72","14,14"
"low bq, many samples",UPN2_105,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),3857,137,4086,"0,0335291238",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"29,11",14
"low bq, many samples",UPN2_106,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),5489,142,5816,"0,0244154058",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"27,88","14,05"
"low bq, many samples",UPN2_107,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),5831,215,6204,"0,0346550613",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,41","14,08"
"low bq, many samples",UPN2_108,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),6451,158,6774,"0,0233244759",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,43","14,36"
"low bq, many samples",UPN2_109,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),5617,176,5921,"0,0297247087",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,8","14,11"
"low bq, many samples",UPN2_110,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),6327,190,6673,"0,0284729507",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"28,65","14,11"
low bq,UPN2_111,21,36206758,A,C,missense_variant(MODERATE|MISSENSE|Tcc/Gcc|p.Ser252Ala/c.754T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),4602,113,4811,"0,0234878404",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,22,Damaging,"29,01",14
"low bq, many samples",UPN2_001,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),1420,100,1617,"0,061842919",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"29,42","14,22"
"low bq, many samples",UPN2_014,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3316,174,3635,"0,0478679505",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,61","14,33"
"low bq, many samples",UPN2_015,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),5121,268,5592,"0,047925608",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"29,27","14,44"
"low bq, many samples",UPN2_016,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2378,141,2657,"0,0530673692",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,93","15,06"
"low bq, many samples",UPN2_017,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),1643,88,1804,"0,0487804878",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,84","15,3"
"low bq, many samples",UPN2_018,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2948,165,3261,"0,0505979761",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,83","14,18"
"low bq, many samples",UPN2_019,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3034,144,3300,"0,0436363636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"29,06","14,46"
"low bq, many samples",UPN2_020,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2249,134,2491,"0,0537936572",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"29,13","15,01"
"low bq, many samples",UPN2_021,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2460,137,2699,"0,0507595406",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"29,28","14,18"
"low bq, many samples",UPN2_002,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2016,114,2267,"0,0502867225",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"29,08","14,77"
"low bq, many samples",UPN2_022,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3026,242,3393,"0,0713233127",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,54","14,56"
"low bq, many samples",UPN2_023,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3872,235,4323,"0,0543603979",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,79","14,99"
"low bq, many samples",UPN2_041,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),5661,401,6287,"0,0637824081",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,62","14,95"
"low bq, many samples",UPN2_024,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),1823,93,2007,"0,0463378176",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,58","14,82"
"low bq, many samples",UPN2_025,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3658,175,3973,"0,0440473194",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"29,61","14,68"
"low bq, many samples",UPN2_026,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),4459,223,4899,"0,0455194938",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,77","14,31"
"low bq, many samples",UPN2_027,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),4022,233,4462,"0,052218736",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,8","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_089,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3529,77,3723,"0,0206822455",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,76","14,45"
"low bq, many samples",UPN2_042,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),7548,324,8281,"0,0391257095",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,63","15,07"
"low bq, many samples",UPN2_028,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2870,151,3136,"0,0481505102",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"29,28","14,57"
"low bq, many samples",UPN2_043,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),4631,209,5061,"0,0412961865",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,74","14,89"
"low bq, many samples",UPN2_044,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),1968,90,2142,"0,0420168067",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,51","15,2"
"low bq, many samples",UPN2_029,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3126,179,3476,"0,0514959724",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"29,01","14,52"
"low bq, many samples",UPN2_030,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3851,201,4197,"0,047891351",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"29,06","14,5"
"low bq, many samples",UPN2_031,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2817,236,3181,"0,0741905061",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,61","14,77"
"low bq, many samples",UPN2_005,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),696,38,773,"0,0491591203",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"29,33","14,34"
"low bq, many samples",UPN2_045,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),5296,249,5804,"0,0429014473",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,5","15,61"
"low bq, many samples",UPN2_032,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),1342,57,1454,"0,0392022008",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,52","14,93"
"low bq, many samples",UPN2_046,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),6311,271,6848,"0,0395735981",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,29,"14,82"
"low bq, many samples",UPN2_033,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2961,182,3273,"0,0556064772",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,94","14,53"
"low bq, many samples",UPN2_034,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),972,46,1068,"0,043071161",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"29,02",14
"low bq, many samples",UPN2_047,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),9058,388,9888,"0,0392394822",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,68","14,92"
"low bq, many samples",UPN2_048,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),6605,278,7130,"0,0389901823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,88","15,14"
"low bq, many samples",UPN2_035,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),4571,368,5151,"0,0714424384",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,67","14,59"
"low bq, many samples",UPN2_036,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3691,216,4095,"0,0527472527",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,91","15,47"
"low bq, many samples",UPN2_006,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),1412,94,1579,"0,059531349",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"29,1","15,13"
"low bq, many samples",UPN2_049,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),5905,358,6555,"0,0546147979",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,67","14,66"
"low bq, many samples",UPN2_050,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),6044,292,6659,"0,043850428",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,67","14,65"
"low bq, many samples",UPN2_037,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),6278,317,6890,"0,0460087083",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,95","15,19"
"low bq, many samples",UPN2_051,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),6179,277,6780,"0,0408554572",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,53","14,87"
"low bq, many samples",UPN2_052,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),5065,210,5533,"0,0379540936",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,55","14,93"
"low bq, many samples",UPN2_038,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),6698,375,7456,"0,0502950644",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,67","14,56"
"low bq, many samples",UPN2_039,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),6933,358,7604,"0,047080484",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"29,22","14,92"
"low bq, many samples",UPN2_053,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),7764,352,8535,"0,0412419449",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,47","15,03"
"low bq, many samples",UPN2_054,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),4466,181,4836,"0,0374276261",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,93","14,69"
"low bq, many samples",UPN2_007,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),4812,316,5390,"0,0586270872",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"29,18","14,81"
"low bq, many samples",UPN2_008,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),7520,473,8409,"0,0562492567",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"29,12","14,14"
"low bq, many samples",UPN2_009,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),5904,390,6657,"0,0585849482",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,29,"14,4"
"low bq, many samples",UPN2_010,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3142,183,3463,"0,0528443546",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"29,08","14,46"
"low bq, many samples",UPN2_011,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3660,238,4142,"0,0574601642",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"29,31","14,85"
"low bq, many samples",UPN2_055,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),7495,344,8231,"0,0417932208",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,6","14,95"
"low bq, many samples",UPN2_056,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2864,120,3126,"0,0383877159",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,92","14,41"
"low bq, many samples",UPN2_090,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),1924,47,2043,"0,0230053842",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,74","15,47"
"low bq, many samples",UPN2_057,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),4962,226,5440,"0,0415441176",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,68","14,82"
"low bq, many samples",UPN2_058,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),4325,208,4749,"0,0437986945",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,65","15,16"
"low bq, many samples",UPN2_059,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),1382,54,1482,"0,036437247",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"27,79","14,81"
"low bq, many samples",UPN2_012,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),1886,181,2163,"0,083680074",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"29,28","14,27"
"low bq, many samples",UPN2_060,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2966,76,3173,"0,0239520958",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,38","14,71"
"low bq, many samples",UPN2_040,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),6906,416,7698,"0,0540400104",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,99","15,6"
"low bq, many samples",UPN2_013,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),1278,87,1447,"0,0601243953",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"29,53","14,8"
"low bq, many samples",UPN2_091,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2638,91,2793,"0,0325814536",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"27,55","14,53"
"low bq, many samples",UPN2_092,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),1288,33,1368,"0,024122807",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,84","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_093,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),1861,40,1960,"0,0204081633",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,52",15
"low bq, many samples",UPN2_061,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3127,76,3340,"0,022754491",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,31","16,16"
"low bq, many samples",UPN2_062,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),4157,109,4416,"0,024682971",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,59","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_063,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2907,66,3082,"0,0214146658",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,46","14,61"
"low bq, many samples",UPN2_064,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2516,64,2680,"0,023880597",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,39","14,28"
"low bq, many samples",UPN2_065,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),452,22,492,"0,0447154472",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"27,65","15,18"
"low bq, many samples",UPN2_067,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),1036,29,1101,"0,0263396912",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,58","15,83"
"low bq, many samples",UPN2_068,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),1635,51,1765,"0,0288951841",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,85","14,84"
"low bq, many samples",UPN2_069,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2383,66,2555,"0,0258317025",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,16","14,61"
"low bq, many samples",UPN2_070,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),1583,50,1706,"0,0293083236",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,36","16,28"
"low bq, many samples",UPN2_071,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),4083,103,4375,"0,0235428571",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,47","14,85"
"low bq, many samples",UPN2_072,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),4953,169,5296,"0,0319108761",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,5","14,96"
"low bq, many samples",UPN2_073,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2383,76,2542,"0,0298977183",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"27,82","14,82"
"low bq, many samples",UPN2_074,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),1088,38,1178,"0,0322580645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,57","15,05"
"low bq, many samples",UPN2_075,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),4097,114,4377,"0,0260452365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,34","15,49"
"low bq, many samples",UPN2_076,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2447,62,2619,"0,0236731577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,34","14,21"
"low bq, many samples",UPN2_077,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2139,58,2290,"0,0253275109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,38","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_078,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3239,75,3430,"0,0218658892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,54","14,44"
"low bq, many samples",UPN2_079,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),1663,47,1790,"0,0262569832",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,34","14,47"
"low bq, many samples",UPN2_080,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),5248,145,5574,"0,0260136347",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,55","15,03"
"low bq, many samples",UPN2_081,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),6781,220,7246,"0,0303615788",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"27,7",15
"low bq, low freq, many artifacts, many samples",UPN2_082,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2052,48,2188,"0,0219378428",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,12","15,19"
"low bq, many samples",UPN2_083,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2835,70,3039,"0,0230338927",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,14","15,26"
"low bq, many samples",UPN2_084,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2665,69,2848,"0,0242275281",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,26","14,64"
"low bq, many samples",UPN2_085,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),1854,50,1984,"0,0252016129",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,34","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_086,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),1037,21,1091,"0,019248396",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,6","15,38"
"low bq, many samples",UPN2_087,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2244,54,2384,"0,0226510067",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,4","14,24"
"low bq, many samples",UPN2_088,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),1734,55,1854,"0,0296655879",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"27,99","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_094,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3817,83,4037,"0,0205598216",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,43","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_095,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),4015,71,4203,"0,0168926957",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"29,24","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_096,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3977,84,4207,"0,0199667221",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,95",14
"low bq, many samples",UPN2_097,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),4488,127,4755,"0,0267087277",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"29,04","14,35"
"low bq, many samples",UPN2_098,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3196,91,3375,"0,026962963",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"27,5","14,87"
"low bq, many samples",UPN2_099,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),1932,47,2045,"0,0229828851",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,44",14
"low bq, many samples",UPN2_100,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),4146,99,4390,"0,0225512528",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,32",14
"low bq, low freq, many artifacts, many samples",UPN2_101,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3617,75,3809,"0,0196902074",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,79",15
"low bq, low freq, many artifacts, many samples",UPN2_102,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3308,63,3502,"0,0179897202",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,56","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_103,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),4213,89,4431,"0,0200857594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"29,17","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_104,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),4409,86,4691,"0,018332978",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,72","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_105,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3857,83,4086,"0,0203132648",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"29,11","15,11"
"low bq, many samples",UPN2_106,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),5489,174,5816,"0,0299174691",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"27,88","14,29"
"low bq, many samples",UPN2_107,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),5831,147,6204,"0,0236943907",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,41","14,24"
"low bq, many samples",UPN2_108,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),6451,154,6774,"0,0227339829",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,43","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_109,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),5617,111,5921,"0,0187468333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,8","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_110,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),6327,139,6673,"0,0208302113",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"28,65","14,63"
"low bq, low freq, many artifacts",UPN2_111,21,36206758,A,T,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser252Thr/c.754T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),4602,88,4811,"0,0182914155",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,16",Neutral,189,Tolerated,"29,01","14,95"
"inspected, many artifacts",UPN2_044,21,36206760,G,A,missense_variant(MODERATE|MISSENSE|gCc/gTc|p.Ala251Val/c.752C>T|480|RUNX1|protein_coding|CODING|ENST00000437180|7|A),2108,23,2145,"0,0107226107",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,68",Neutral,"0,072",Tolerated,"30,67","27,35"
"inspected, many artifacts",UPN2_064,21,36206760,G,A,missense_variant(MODERATE|MISSENSE|gCc/gTc|p.Ala251Val/c.752C>T|480|RUNX1|protein_coding|CODING|ENST00000437180|7|A),2637,30,2682,"0,0111856823",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,68",Neutral,"0,072",Tolerated,"31,77","27,27"
"low bq, many samples",UPN2_001,21,36206763,C,G,missense_variant(MODERATE|MISSENSE|cGt/cCt|p.Arg250Pro/c.749G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1591,44,1636,"0,0268948655",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,7",Deleterious,24,Damaging,"28,41","14,41"
"low bq, many samples",UPN2_006,21,36206763,C,G,missense_variant(MODERATE|MISSENSE|cGt/cCt|p.Arg250Pro/c.749G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1556,41,1597,"0,0256731371",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,7",Deleterious,24,Damaging,"28,62",14
"low bq, many samples",UPN2_059,21,36206763,C,G,missense_variant(MODERATE|MISSENSE|cGt/cCt|p.Arg250Pro/c.749G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1374,113,1489,"0,075889859",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,7",Deleterious,24,Damaging,"27,32","14,49"
"low bq, many samples",UPN2_062,21,36206763,C,G,missense_variant(MODERATE|MISSENSE|cGt/cCt|p.Arg250Pro/c.749G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4200,214,4433,"0,0482743063",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,7",Deleterious,24,Damaging,"27,75","14,55"
"low bq, many samples",UPN2_065,21,36206763,C,G,missense_variant(MODERATE|MISSENSE|cGt/cCt|p.Arg250Pro/c.749G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),450,41,494,"0,0829959514",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,7",Deleterious,24,Damaging,"27,31","14,66"
"low bq, many samples",UPN2_066,21,36206763,C,G,missense_variant(MODERATE|MISSENSE|cGt/cCt|p.Arg250Pro/c.749G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),621,33,656,"0,050304878",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,7",Deleterious,24,Damaging,"27,97",14
"low bq, many samples",UPN2_067,21,36206763,C,G,missense_variant(MODERATE|MISSENSE|cGt/cCt|p.Arg250Pro/c.749G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1036,67,1103,"0,060743427",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,7",Deleterious,24,Damaging,"27,54","14,81"
"low bq, many samples",UPN2_070,21,36206763,C,G,missense_variant(MODERATE|MISSENSE|cGt/cCt|p.Arg250Pro/c.749G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1613,105,1718,"0,0611175786",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,7",Deleterious,24,Damaging,"27,68","14,38"
"low bq, many samples",UPN2_074,21,36206763,C,G,missense_variant(MODERATE|MISSENSE|cGt/cCt|p.Arg250Pro/c.749G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1113,66,1181,"0,0558848434",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,7",Deleterious,24,Damaging,"27,33","14,52"
"low bq, many samples",UPN2_079,21,36206763,C,G,missense_variant(MODERATE|MISSENSE|cGt/cCt|p.Arg250Pro/c.749G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1697,99,1798,"0,0550611791",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,7",Deleterious,24,Damaging,"27,72","14,41"
"low bq, many samples",UPN2_080,21,36206763,C,G,missense_variant(MODERATE|MISSENSE|cGt/cCt|p.Arg250Pro/c.749G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5223,341,5590,"0,0610017889",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,7",Deleterious,24,Damaging,"27,69","14,68"
"low bq, many samples",UPN2_083,21,36206763,C,G,missense_variant(MODERATE|MISSENSE|cGt/cCt|p.Arg250Pro/c.749G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2864,173,3049,"0,0567399147",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,7",Deleterious,24,Damaging,"27,44","14,54"
"low bq, many samples",UPN2_084,21,36206763,C,G,missense_variant(MODERATE|MISSENSE|cGt/cCt|p.Arg250Pro/c.749G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2658,191,2858,"0,066829951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,7",Deleterious,24,Damaging,"27,34","14,87"
"low bq, many samples",UPN2_085,21,36206763,C,G,missense_variant(MODERATE|MISSENSE|cGt/cCt|p.Arg250Pro/c.749G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1877,109,1991,"0,0547463586",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,7",Deleterious,24,Damaging,"27,55","14,73"
"low bq, many samples",UPN2_086,21,36206763,C,G,missense_variant(MODERATE|MISSENSE|cGt/cCt|p.Arg250Pro/c.749G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1032,60,1094,"0,0548446069",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,7",Deleterious,24,Damaging,"28,21","14,45"
low bq,UPN2_087,21,36206763,C,G,missense_variant(MODERATE|MISSENSE|cGt/cCt|p.Arg250Pro/c.749G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2246,142,2394,"0,0593149541",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,7",Deleterious,24,Damaging,"27,64","14,51"
"low bq, low freq, many artifacts",UPN2_012,21,36206768,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn248Lys/c.744C>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2263,28,2294,"0,0122057541",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,02",Deleterious,48,Damaging,"31,62",26
"low bq, low freq, many artifacts, many samples",UPN2_014,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3738,45,3800,"0,0118421053",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"27,43","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_015,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5694,68,5808,"0,011707989",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"27,37","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_016,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2713,37,2767,"0,0133718829",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"27,87","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_019,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3346,54,3413,"0,0158218576",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"27,17",14
"low bq, low freq, many artifacts, many samples",UPN2_020,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2549,36,2599,"0,0138514813",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"27,58","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_021,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2776,32,2820,"0,0113475177",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"27,61",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_002,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2349,33,2395,"0,0137787056",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"26,66","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_022,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3513,38,3569,"0,0106472401",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"27,29",14
"low bq, low freq, many artifacts, many samples",UPN2_023,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4424,59,4509,"0,0130849412",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"27,11","14,59"
"low freq, many artifacts, many samples",UPN2_041,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6550,142,6726,"0,0211121023",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,27,"14,84"
"low bq, low freq, many artifacts, many samples",UPN2_024,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2046,25,2084,"0,0119961612",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"27,44","14,72"
"low bq, bad alignment, many samples",UPN2_089,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3692,102,3806,"0,0267997898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"26,62","14,27"
"low bq, bad alignment, many samples",UPN2_042,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),8486,227,8771,"0,0258807434",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"26,98","14,53"
"low bq, bad alignment, many samples",UPN2_043,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5160,140,5333,"0,0262516407",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"26,97",14
"low bq, many samples",UPN2_044,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2167,54,2238,"0,0241286863",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"27,01","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_029,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3542,58,3613,"0,0160531414",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"27,21","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_030,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4280,51,4349,"0,0117268338",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"27,56","15,04"
"low bq, bad alignment, many samples",UPN2_045,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5938,155,6117,"0,0253392186",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"26,89","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_046,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6985,139,7167,"0,0193944468",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"27,07","14,55"
"low bq, bad alignment, many samples",UPN2_047,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),10148,243,10435,"0,0232870149",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"26,97","14,36"
"low bq, many samples",UPN2_048,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),7280,167,7507,"0,0222459038",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"27,2","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_035,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5349,60,5429,"0,0110517591",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"27,3","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_006,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1629,25,1665,"0,015015015",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"27,08",14
"low bq, bad alignment, many samples",UPN2_049,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6803,163,7000,"0,0232857143",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"26,91","14,42"
"low bq, bad alignment, many samples",UPN2_050,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6838,158,7036,"0,0224559409",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"26,79","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_037,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6997,109,7137,"0,0152725235",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"27,48","14,39"
"low bq, many samples",UPN2_051,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6920,184,7138,"0,0257775287",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"27,05","14,49"
"low bq, bad alignment, many samples",UPN2_052,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5648,139,5808,"0,0239325069",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"26,75","14,71"
"low bq, bad alignment, many samples",UPN2_053,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),8701,214,8958,"0,023889261",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"26,8","14,48"
"low bq, bad alignment, many samples",UPN2_054,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4937,130,5097,"0,0255051991",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"26,93","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_007,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5582,79,5679,"0,0139108998",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"27,72","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_008,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),8659,140,8847,"0,0158245733",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"27,38","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_009,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6884,123,7026,"0,0175064048",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"27,18","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_010,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3534,61,3608,"0,0169068736",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"27,58","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_011,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4275,68,4364,"0,0155820348",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"27,34",14
"low bq, bad alignment, many samples",UPN2_055,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),8343,207,8627,"0,0239944361",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"26,92","14,3"
"low bq, many samples",UPN2_056,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3169,80,3268,"0,0244798042",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"27,3","14,18"
"low bq, bad alignment, many samples",UPN2_090,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2045,48,2100,"0,0228571429",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"26,68","14,67"
"low bq, bad alignment, many samples",UPN2_057,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5552,136,5730,"0,0237347295",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"26,91","14,68"
"low bq, many samples",UPN2_058,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4819,122,4974,"0,0245275432",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"27,16","14,22"
"low bq, low freq, many artifacts, many samples",UPN2_040,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),7828,117,8004,"0,0146176912",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"27,54","14,55"
"low bq, bad alignment, many samples",UPN2_091,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2783,65,2861,"0,0227193289",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"26,79","14,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_092,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1391,31,1424,"0,0217696629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"26,54",14
"low bq, bad alignment, many samples",UPN2_093,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1944,59,2012,"0,0293240557",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"26,76","14,24"
"low bq, bad alignment, many samples",UPN2_066,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),634,37,676,"0,0547337278",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"25,9","14,38"
"low bq, bad alignment, many samples",UPN2_067,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1077,54,1137,"0,0474934037",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"25,37","14,63"
"low bq, bad alignment, many samples",UPN2_070,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1647,104,1759,"0,0591245026",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"25,18","15,03"
"low bq, bad alignment, many samples",UPN2_072,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5108,276,5415,"0,0509695291",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"25,07","14,69"
"low bq, bad alignment, many samples",UPN2_074,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1136,71,1210,"0,058677686",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"25,26","15,63"
"low bq, bad alignment, many samples",UPN2_086,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1055,67,1129,"0,0593445527",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"25,31","14,96"
"low bq, bad alignment, many samples",UPN2_094,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4008,109,4139,"0,0263348635",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"26,62","14,39"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_095,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4195,84,4293,"0,0195667365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"26,82","14,24"
"low bq, bad alignment, many samples",UPN2_096,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4153,127,4295,"0,0295692666",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"26,89","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_097,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4729,104,4842,"0,0214787278",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"27,02",14
"low bq, bad alignment, many samples",UPN2_098,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3371,83,3470,"0,0239193084",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"26,57","14,08"
"low bq, bad alignment, many samples",UPN2_099,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2024,60,2095,"0,0286396181",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"26,7","14,12"
"low bq, bad alignment, many samples",UPN2_100,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4355,112,4488,"0,0249554367",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"26,64","14,5"
"low bq, bad alignment, many samples",UPN2_101,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3765,100,3885,"0,0257400257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"26,79","14,47"
"low bq, bad alignment, many samples",UPN2_102,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3465,96,3581,"0,0268081541",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"26,6","14,22"
"low bq, bad alignment, many samples",UPN2_103,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4406,111,4528,"0,0245141343",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"26,79","14,62"
"low bq, bad alignment, many samples",UPN2_104,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4665,119,4805,"0,0247658689",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"26,59","14,12"
"low bq, bad alignment, many samples",UPN2_105,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4058,108,4172,"0,0258868648",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"26,81","14,26"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_106,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5855,118,5993,"0,0196896379",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"26,68","14,42"
"low bq, bad alignment, many samples",UPN2_107,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6124,181,6333,"0,0285804516",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"26,73","14,23"
"low bq, bad alignment, many samples",UPN2_108,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6741,189,6945,"0,0272138229",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"26,9","14,29"
"low bq, bad alignment, many samples",UPN2_109,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5859,172,6048,"0,0284391534",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"26,71","14,2"
"low bq, bad alignment, many samples",UPN2_110,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6630,160,6805,"0,0235121234",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"26,91","14,54"
"low bq, low freq, many artifacts",UPN2_111,21,36206769,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn248Thr/c.743A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4774,106,4895,"0,0216547497",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"1,65E-005",NO,NO,"-2,71",Deleterious,117,Tolerated,"27,03","14,32"
"low bq, many samples",UPN2_015,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5057,740,5826,"0,1270168211",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,6","15,2"
"low bq, many samples",UPN2_016,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2369,395,2772,"0,1424963925",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,9","15,09"
"low bq, many samples",UPN2_017,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1632,233,1870,"0,1245989305",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,44",15
"low bq, many samples",UPN2_018,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2906,488,3402,"0,1434450323",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,67","15,23"
"low bq, many samples",UPN2_019,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2985,418,3422,"0,122150789",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,66","15,07"
"low bq, many samples",UPN2_003,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),420,51,473,"0,1078224101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,5","15,14"
"low bq, many samples",UPN2_041,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5657,1061,6747,"0,1572550763",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,98","15,4"
"low bq, many samples",UPN2_004,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),291,41,332,"0,1234939759",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,48","16,24"
"low bq, many samples",UPN2_089,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3342,454,3809,"0,1191913888",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,41","15,07"
"low bq, many samples",UPN2_042,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),7570,1200,8816,"0,1361161525",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,59","15,76"
"low bq, many samples",UPN2_043,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4615,721,5356,"0,1346153846",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,83","15,42"
"low bq, many samples",UPN2_044,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1928,312,2253,"0,138482024",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,73","15,4"
"low bq, many samples",UPN2_029,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3119,486,3618,"0,1343283582",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,67","14,88"
"low bq, many samples",UPN2_030,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3802,531,4354,"0,1219568213",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,53","15,09"
"low bq, many samples",UPN2_005,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),708,109,817,"0,1334149327",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,85","15,16"
"low bq, many samples",UPN2_045,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5267,862,6150,"0,1401626016",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,48","15,45"
"low bq, many samples",UPN2_032,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1334,189,1528,"0,1236910995",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,55","14,97"
"low bq, many samples",UPN2_046,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6231,927,7192,"0,1288932147",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,71","15,2"
"low bq, many samples",UPN2_033,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2936,475,3423,"0,1387671633",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,74","15,32"
"low bq, many samples",UPN2_034,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),970,151,1122,"0,1345811052",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,46","14,86"
"low bq, many samples",UPN2_047,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),9085,1359,10484,"0,1296260969",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,55","15,44"
"low bq, many samples",UPN2_048,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6620,885,7531,"0,1175142743",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,5","15,52"
"low bq, many samples",UPN2_036,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3623,631,4269,"0,1478097915",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,87","14,99"
"low bq, many samples",UPN2_006,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1474,189,1671,"0,1131059246",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,64","15,55"
"low bq, many samples",UPN2_049,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5927,1085,7037,"0,154185022",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,97","15,58"
"low bq, many samples",UPN2_050,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6037,997,7070,"0,1410183876",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,78","15,21"
"low bq, many samples, no database",UPN2_037,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6204,926,7154,"0,1294380766",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,"0,029",Damaging,"27,62","15,13"
"low bq, many samples",UPN2_052,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5009,812,5841,"0,1390172916",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,63","15,49"
"low bq, many samples",UPN2_038,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6574,1142,7741,"0,1475261594",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,67","15,09"
"low bq, many samples",UPN2_039,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6877,985,7887,"0,1248890579",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,61","14,9"
"low bq, many samples",UPN2_053,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),7684,1268,8999,"0,1409045449",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,64","15,66"
"low bq, many samples",UPN2_054,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4482,621,5119,"0,1213127564",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,58","15,22"
"low bq, many samples",UPN2_009,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6094,929,7049,"0,1317917435",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,74","15,64"
"low bq, many samples",UPN2_011,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3835,543,4383,"0,1238877481",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,89","15,82"
"low bq, many samples",UPN2_055,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),7477,1148,8659,"0,1325788197",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,52","15,53"
"low bq, many samples",UPN2_056,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2854,417,3281,"0,1270953977",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,59","15,27"
"low bq, many samples",UPN2_090,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1852,246,2102,"0,1170313987",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,36","14,87"
"low bq, many samples",UPN2_057,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4943,798,5754,"0,1386861314",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,8","15,26"
"low bq, many samples",UPN2_058,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4333,646,4995,"0,1293293293",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,46","15,05"
"low bq, many samples",UPN2_012,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1954,349,2309,"0,151147683",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,89","15,73"
"low bq, many samples",UPN2_040,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6902,1098,8027,"0,1367883394",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,66","15,27"
"low bq, many samples",UPN2_092,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1238,188,1428,"0,1316526611",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,78","15,25"
"low bq, many samples",UPN2_093,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1779,227,2016,"0,1125992063",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,43","15,1"
"low bq, bad alignment, many samples",UPN2_061,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2861,554,3425,"0,1617518248",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"26,94","15,71"
"low bq, many samples",UPN2_064,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2359,374,2742,"0,1363967907",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,07","15,84"
"low bq, many samples",UPN2_065,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),415,92,508,"0,1811023622",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,4","15,37"
"low bq, bad alignment, many samples",UPN2_066,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),577,98,682,"0,1436950147",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"26,96","15,02"
"low bq, bad alignment, many samples",UPN2_067,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),969,167,1140,"0,1464912281",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"26,65","16,01"
"low bq, many samples, no database",UPN2_069,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2197,425,2636,"0,1612291351",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,"0,029",Damaging,"26,89","15,92"
"low bq, many samples",UPN2_070,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1496,264,1765,"0,1495750708",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,13","16,05"
"low bq, many samples",UPN2_071,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3828,651,4493,"0,1448920543",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,05","15,53"
"low bq, many samples, no database",UPN2_072,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4618,777,5432,"0,1430412371",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,"0,029",Damaging,"26,65","15,98"
"low bq, many samples",UPN2_074,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1009,198,1213,"0,163231657",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,1","15,65"
"low bq, bad alignment, many samples",UPN2_076,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2246,427,2681,"0,1592689295",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"26,56","15,7"
"low bq, many samples, no database",UPN2_077,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1958,368,2338,"0,1573994867",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,"0,029",Damaging,"26,8","15,57"
"low bq, bad alignment, many samples",UPN2_078,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3032,470,3511,"0,1338649957",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"26,51","15,4"
"low bq, bad alignment, many samples",UPN2_079,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1561,282,1848,"0,1525974026",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"26,8","15,85"
"low bq, bad alignment, many samples",UPN2_080,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4871,821,5709,"0,1438080224",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"26,79","15,6"
"low bq, bad alignment, many samples",UPN2_081,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6179,1264,7473,"0,1691422454",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"26,76","15,69"
"low bq, bad alignment, many samples",UPN2_083,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2618,484,3110,"0,1556270096",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"26,68","15,74"
"low bq, bad alignment, many samples",UPN2_084,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2453,466,2931,"0,1589901058",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"26,71","15,62"
"low bq, bad alignment, many samples",UPN2_085,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1709,321,2036,"0,1576620825",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"26,94","15,84"
"low bq, bad alignment, many samples",UPN2_086,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),976,153,1133,"0,1350397176",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"26,55","15,42"
"low bq, bad alignment, many samples",UPN2_087,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2064,374,2445,"0,1529652352",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"26,75","15,71"
"low bq, many samples",UPN2_088,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1593,304,1900,"0,16",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,27","15,95"
"low bq, many samples, no database",UPN2_094,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3629,503,4146,"0,1213217559",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,"0,029",Damaging,"27,41","15,14"
"low bq, many samples",UPN2_095,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3866,423,4297,"0,0984407726",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,44","14,94"
"low bq, many samples, no database",UPN2_096,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3781,521,4308,"0,1209377902",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,"0,029",Damaging,"27,38","14,85"
"low bq, many samples, no database",UPN2_097,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4308,529,4847,"0,109139674",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,"0,029",Damaging,"27,66",15
"low bq, many samples",UPN2_099,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1840,258,2102,"0,1227402474",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,6","15,22"
"low bq, many samples, no database",UPN2_101,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3400,486,3893,"0,1248394554",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,"0,029",Damaging,"27,5","15,02"
"low bq, many samples",UPN2_102,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3142,440,3589,"0,1225968236",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,43","14,81"
"low bq, many samples",UPN2_103,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4051,486,4541,"0,1070248844",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,35","14,97"
"low bq, many samples, no database",UPN2_104,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4274,534,4815,"0,1109034268",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,"0,029",Damaging,"27,33","15,19"
"low bq, many samples",UPN2_105,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3701,462,4178,"0,1105792245",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,58","14,79"
"low bq, many samples",UPN2_106,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5170,813,6002,"0,1354548484",0,0,0,0,0,1,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,38","14,91"
"low bq, many samples, no database",UPN2_107,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5578,753,6344,"0,1186948298",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,"0,029",Damaging,"27,26","14,68"
"low bq, many samples",UPN2_108,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6132,816,6962,"0,1172076989",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,36","14,74"
"low bq, many samples",UPN2_109,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5382,668,6058,"0,110267415",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,4","14,95"
"low bq, many samples, no database",UPN2_110,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6016,785,6824,"0,11503517",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,"0,029",Damaging,"27,43","14,87"
low bq,UPN2_111,21,36206770,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn248His/c.742A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4364,514,4899,"0,1049193713",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,77",Deleterious,29,Damaging,"27,43","14,59"
"inspected, many artifacts",UPN2_025,21,36206774,C,CGTGGGGGCTGGGTG,frameshift_variant(HIGH||acg/acCACCCAGCCCCCACg|p.Pro247fs/c.724_737dupCACCCAGCCCCCAC|480|RUNX1|protein_coding|CODING|ENST00000437180|7|CGTGGGGGCTGGGTG),4049,460,4233,"0,108669974",0,1,0,1,0,1,0,1,4,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,62",NA
"low freq, many artifacts",UPN2_044,21,36206776,T,C,missense_variant(MODERATE|MISSENSE|Acg/Gcg|p.Thr246Ala/c.736A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1862,29,2332,"0,0124356775",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,91",Neutral,91,Tolerated,"27,01","28,45"
"low bq, many samples",UPN2_014,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3128,807,3950,"0,2043037975",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,2","15,24"
"low bq, many samples",UPN2_015,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4966,1042,6033,"0,1727167247",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,29","15,28"
"low bq, many samples",UPN2_016,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2304,581,2897,"0,2005522955",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,28","15,17"
"low bq, bad alignment, many samples",UPN2_017,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1576,355,1939,"0,183084064",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"26,74","15,36"
"low bq, many samples",UPN2_018,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2824,708,3551,"0,1993804562",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,1","15,28"
"low bq, many samples",UPN2_020,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2210,499,2717,"0,1836584468",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,06","15,4"
"low bq, bad alignment, many samples",UPN2_021,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2427,501,2939,"0,1704661449",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"26,95","15,09"
"low bq, many samples",UPN2_002,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2004,520,2542,"0,204563336",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,22","16,44"
"low bq, many samples, no database",UPN2_022,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2857,845,3723,"0,2269674993",1,0,0,0,0,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,"0,302",Tolerated,"27,52","15,05"
"low bq, many samples",UPN2_023,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3743,913,4670,"0,195503212",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,12","15,29"
"low bq, many samples",UPN2_041,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5413,1596,7057,"0,2261584243",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,64","15,6"
"low bq, many samples",UPN2_024,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1767,402,2174,"0,1849126035",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,04","15,03"
"low bq, many samples",UPN2_025,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3520,721,4264,"0,1690900563",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"28,11","15,51"
"low bq, many samples",UPN2_026,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4253,1021,5294,"0,1928598413",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,09","15,36"
"low bq, bad alignment, many samples",UPN2_004,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),294,58,352,"0,1647727273",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"26,96","15,76"
"low bq, many samples",UPN2_027,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3883,925,4832,"0,1914321192",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,12","15,45"
"low bq, bad alignment, many samples",UPN2_089,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3261,592,3866,"0,15312985",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"26,94","15,05"
"low bq, many samples",UPN2_042,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),7329,1769,9145,"0,1934390377",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,35","15,72"
"low bq, bad alignment, many samples",UPN2_028,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2827,545,3390,"0,1607669617",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"26,85","15,5"
"low bq, many samples",UPN2_043,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4474,1099,5608,"0,1959700428",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,41","15,57"
"low bq, many samples",UPN2_044,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1862,435,2332,"0,186535163",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,01","15,63"
"low bq, many samples",UPN2_029,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3050,701,3757,"0,1865850413",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,07","15,37"
"low bq, many samples",UPN2_030,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3726,770,4519,"0,1703916796",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,05","15,07"
"low bq, many samples",UPN2_031,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2674,822,3509,"0,2342547734",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,84","15,26"
"low bq, many samples",UPN2_045,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5111,1228,6370,"0,1927786499",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,12","15,65"
"low bq, many samples",UPN2_046,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6215,1211,7466,"0,1622019823",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,06","15,57"
"low bq, many samples",UPN2_033,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2869,699,3577,"0,1954151524",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,21","15,24"
"low bq, bad alignment, many samples",UPN2_034,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),944,227,1173,"0,1935208866",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"26,97","15,88"
"low bq, many samples",UPN2_047,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),8880,1961,10893,"0,1800238685",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,15","15,8"
"low bq, many samples",UPN2_048,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6427,1346,7808,"0,1723872951",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,19","15,74"
"low bq, many samples",UPN2_035,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4403,1265,5700,"0,2219298246",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,49","15,12"
"low bq, many samples",UPN2_036,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3534,894,4449,"0,2009440324",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,38","15,5"
"low bq, many samples",UPN2_006,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1440,301,1753,"0,1717056475",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,12","16,27"
"low bq, many samples, no database",UPN2_049,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5637,1743,7407,"0,2353179425",1,0,0,0,0,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,"0,302",Tolerated,"27,89","15,84"
"low bq, many samples",UPN2_050,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5828,1520,7399,"0,2054331666",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,52","15,87"
"low bq, many samples",UPN2_037,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6039,1384,7452,"0,1857219538",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,07","15,41"
"low bq, many samples",UPN2_051,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5997,1473,7502,"0,1963476406",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,37","15,59"
"low bq, many samples",UPN2_052,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4884,1161,6069,"0,1913000494",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,2","15,66"
"low bq, many samples",UPN2_038,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6399,1641,8065,"0,2034717917",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,1","15,44"
"low bq, many samples",UPN2_039,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6797,1357,8186,"0,1657708282",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,16","15,12"
"low bq, many samples",UPN2_053,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),7579,1783,9418,"0,1893183266",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,07","16,03"
many samples,UPN2_054,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4408,857,5296,"0,1618202417",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,27,"15,86"
"low bq, many samples",UPN2_007,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4743,1220,5983,"0,2039110814",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,71","16,15"
"low bq, many samples",UPN2_008,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),7416,1827,9270,"0,1970873786",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,27","16,12"
"low bq, many samples",UPN2_009,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5832,1519,7378,"0,2058823529",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,46","15,9"
"low bq, many samples",UPN2_010,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3090,676,3775,"0,1790728477",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,34","15,91"
"low bq, many samples",UPN2_055,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),7289,1700,9039,"0,188073902",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,05","15,81"
"low bq, many samples",UPN2_056,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2831,581,3425,"0,1696350365",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,1","16,03"
"low bq, many samples",UPN2_057,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4794,1167,5993,"0,1947271817",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,1","15,62"
"low bq, many samples, no database",UPN2_058,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4165,1024,5209,"0,1965828374",1,0,0,0,0,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,"0,302",Tolerated,"27,27","15,76"
"low bq, many samples",UPN2_012,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1849,578,2433,"0,23756679",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"28,05","15,97"
"low bq, bad alignment, many samples",UPN2_060,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2670,655,3335,"0,1964017991",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"26,19","16,02"
"low bq, many samples",UPN2_040,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6725,1599,8351,"0,191474075",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,22","15,2"
"low bq, many samples",UPN2_091,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2337,573,2916,"0,1965020576",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,08","14,89"
"low bq, bad alignment, many samples",UPN2_061,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2777,707,3503,"0,2018270054",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"26,11","16,05"
"low bq, bad alignment, many samples",UPN2_062,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3825,775,4619,"0,1677852349",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"25,97","15,94"
"low bq, bad alignment, many samples",UPN2_063,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2609,625,3243,"0,1927227875",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"26,22","16,2"
"low bq, bad alignment, many samples",UPN2_064,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2312,473,2794,"0,1692913386",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"25,89","16,04"
"low bq, bad alignment, many samples",UPN2_065,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),407,118,526,"0,2243346008",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"26,9","15,25"
"low bq, bad alignment, many samples",UPN2_066,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),573,118,691,"0,1707670043",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"26,39","16,22"
"low bq, bad alignment, many samples",UPN2_067,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),953,211,1166,"0,1809605489",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"26,3","16,74"
"low bq, bad alignment, many samples",UPN2_068,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1495,362,1859,"0,1947283486",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"25,7","15,88"
"low bq, bad alignment, many samples",UPN2_069,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2143,552,2700,"0,2044444444",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"26,13","15,91"
"low bq, bad alignment, many samples",UPN2_070,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1457,332,1798,"0,1846496107",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"26,32","15,82"
"low bq, bad alignment, many samples",UPN2_071,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3699,863,4588,"0,1880993897",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"26,21","15,86"
"low bq, bad alignment, many samples",UPN2_072,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4536,987,5540,"0,1781588448",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,26,"16,22"
"low bq, bad alignment, many samples",UPN2_074,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),990,238,1238,"0,1922455574",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"25,75","16,01"
"low bq, many samples, no database",UPN2_075,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3673,876,4577,"0,1913917413",1,0,0,0,0,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,"0,302",Tolerated,"26,18","15,64"
"low bq, bad alignment, many samples",UPN2_076,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2202,525,2731,"0,1922372757",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"26,13","15,9"
"low bq, bad alignment, many samples",UPN2_077,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1884,483,2387,"0,2023460411",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"26,06","15,8"
"low bq, bad alignment, many samples",UPN2_078,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2961,608,3583,"0,1696902037",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"25,64","15,89"
"low bq, bad alignment, many samples",UPN2_080,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4803,983,5812,"0,1691328286",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"25,91","15,78"
"low bq, bad alignment, many samples",UPN2_081,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6015,1607,7651,"0,2100379035",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"25,95","16,02"
"low bq, bad alignment, many samples",UPN2_082,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1854,440,2303,"0,1910551455",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"26,4","16,05"
"low bq, bad alignment, many samples",UPN2_083,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2511,643,3166,"0,2030953885",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"25,93","16,05"
"low bq, bad alignment, many samples",UPN2_084,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2405,574,2991,"0,1919090605",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"26,03","16,23"
"low bq, bad alignment, many samples",UPN2_085,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1678,391,2077,"0,188252287",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"25,98","15,98"
"low bq, bad alignment, many samples",UPN2_087,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2032,464,2502,"0,1854516387",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"26,13","16,2"
"low bq, bad alignment, many samples",UPN2_088,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1537,404,1946,"0,2076053443",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"26,28","16,62"
"low bq, bad alignment, many samples",UPN2_094,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3569,641,4218,"0,1519677572",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"26,94","15,03"
"low bq, many samples",UPN2_095,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3739,590,4352,"0,1355698529",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,33","15,36"
"low bq, many samples",UPN2_097,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4202,708,4926,"0,143727162",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,28","15,31"
"low bq, many samples",UPN2_098,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2881,660,3546,"0,1861252115",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,01","14,98"
"low bq, many samples",UPN2_099,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1784,358,2148,"0,1666666667",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,23","15,18"
"low bq, many samples",UPN2_100,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3787,776,4576,"0,1695804196",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,14","14,91"
"low bq, many samples",UPN2_101,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3286,660,3954,"0,1669195751",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,27","15,3"
"low bq, many samples",UPN2_102,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3038,604,3665,"0,1648021828",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,04","15,64"
"low bq, many samples",UPN2_103,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3976,623,4616,"0,134965338",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,08","14,85"
"low bq, bad alignment, many samples",UPN2_106,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4933,1162,6121,"0,1898382617",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"26,9","14,98"
"low bq, many samples",UPN2_107,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5336,1087,6443,"0,1687102282",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,23","15,13"
"low bq, many samples",UPN2_108,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5927,1131,7069,"0,1599943415",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,05","14,91"
"low bq, many samples",UPN2_109,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5150,980,6147,"0,1594273629",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,11","15,29"
"low bq, many samples",UPN2_110,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5782,1121,6919,"0,1620176326",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,23","14,86"
low bq,UPN2_111,21,36206776,T,G,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr246Pro/c.736A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4327,618,4959,"0,1246218996",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,302,Tolerated,"27,01","15,15"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_001,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1839,34,1896,"0,0179324895",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,88","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_014,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3921,74,4029,"0,0183668404",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,02","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_015,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6047,94,6182,"0,0152054351",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,43","14,15"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_016,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2896,49,2963,"0,0165372933",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,88","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_017,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1937,35,1979,"0,0176856998",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,64",14
"low bq, low freq, many artifacts, many samples",UPN2_018,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3534,61,3624,"0,0168322296",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,1","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_019,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3531,71,3625,"0,0195862069",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,72","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_020,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2714,49,2780,"0,0176258993",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,42","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_021,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2922,41,2990,"0,0137123746",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,52",14
"low bq, many samples",UPN2_002,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2522,58,2612,"0,0222052067",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,34","14,12"
"low bq, bad alignment, many samples",UPN2_022,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3713,85,3831,"0,0221874184",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"25,84","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_023,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4655,99,4790,"0,0206680585",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,24","14,32"
"low bq, bad alignment, many samples",UPN2_041,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6864,244,7234,"0,0337296102",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"25,94","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_024,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2164,41,2222,"0,0184518452",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,25","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_025,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4482,92,4599,"0,0200043488",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,05","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_026,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5296,74,5396,"0,0137138621",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,5","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_027,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4838,72,4932,"0,0145985401",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,19","14,68"
"low bq, many samples",UPN2_089,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3790,93,3893,"0,0238890316",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,04","14,42"
"low bq, bad alignment, many samples",UPN2_042,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),8961,275,9344,"0,0294306507",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,79","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_028,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3368,69,3467,"0,0199019325",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,83","15,03"
"low bq, bad alignment, many samples",UPN2_043,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5493,169,5726,"0,0295144953",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,78","14,62"
"low bq, many samples",UPN2_044,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2295,53,2369,"0,022372309",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,23","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_029,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3739,73,3843,"0,0189955764",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,21","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_030,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4489,82,4620,"0,0177489177",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,67","15,11"
"low bq, bad alignment, many samples",UPN2_031,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3490,88,3609,"0,0243834857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"25,9","14,2"
"low bq, bad alignment, many samples",UPN2_045,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6271,173,6519,"0,0265378125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,74","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_032,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1591,30,1632,"0,0183823529",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,2",14
"low bq, many samples",UPN2_046,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),7312,206,7603,"0,0270945679",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,32","14,42"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_033,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3597,79,3696,"0,0213744589",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,92","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_034,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1149,23,1188,"0,0193602694",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,11",14
"low bq, bad alignment, many samples",UPN2_047,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),10703,309,11115,"0,0278002699",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,99","14,39"
"low bq, many samples",UPN2_048,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),7652,223,7955,"0,0280326838",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,2","14,21"
"low bq, bad alignment, many samples",UPN2_035,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5675,142,5871,"0,0241866803",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"25,96","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_036,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4419,76,4550,"0,0167032967",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,19","14,17"
"low bq, many samples",UPN2_006,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1739,46,1805,"0,0254847645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,52",14
"low bq, bad alignment, many samples",UPN2_049,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),7260,238,7594,"0,031340532",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"25,96","14,41"
"low bq, bad alignment, many samples",UPN2_050,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),7281,190,7550,"0,0251655629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,81","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_037,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),7427,159,7631,"0,0208360634",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,53","14,38"
"low bq, bad alignment, many samples",UPN2_051,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),7346,207,7632,"0,0271226415",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,77","14,29"
"low bq, many samples",UPN2_052,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5929,142,6164,"0,023036989",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,16","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_038,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),8027,152,8236,"0,018455561",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,13","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_039,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),8157,149,8361,"0,0178208348",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,75","14,32"
"low bq, bad alignment, many samples",UPN2_053,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),9241,269,9608,"0,0279975021",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,81","14,86"
"low bq, many samples",UPN2_054,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5179,146,5380,"0,0271375465",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,28","14,47"
"low bq, many samples",UPN2_007,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5979,145,6186,"0,0234400259",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,15","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_008,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),9254,189,9531,"0,0198300283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,36","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_009,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),7357,162,7600,"0,0213157895",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,04","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_010,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3752,82,3868,"0,0211995863",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,74","14,44"
"low bq, many samples",UPN2_011,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4545,107,4718,"0,0226791013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,23","14,19"
"low bq, many samples",UPN2_055,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),8907,235,9233,"0,0254521824",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,07","14,5"
"low bq, many samples",UPN2_056,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3356,97,3488,"0,027809633",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,07","14,21"
"low bq, bad alignment, many samples",UPN2_090,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2092,48,2150,"0,0223255814",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,86","14,42"
"low bq, bad alignment, many samples",UPN2_057,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5888,152,6092,"0,0249507551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,81","14,39"
"low bq, many samples",UPN2_058,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5107,124,5298,"0,0234050585",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,03","14,57"
"low bq, bad alignment, many samples",UPN2_059,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1517,58,1583,"0,0366392925",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"25,93","14,12"
"low bq, bad alignment, many samples",UPN2_012,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2447,58,2537,"0,0228616476",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"25,94","14,22"
"low bq, bad alignment, many samples",UPN2_060,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3232,102,3351,"0,030438675",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,66","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_040,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),8314,135,8497,"0,0158879605",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,24","14,13"
"low bq, low freq, many artifacts, many samples",UPN2_013,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1588,30,1637,"0,0183262065",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,77","14,87"
"low bq, bad alignment, many samples",UPN2_091,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2841,81,2937,"0,0275791624",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"25,7","14,41"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_092,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1439,30,1472,"0,0203804348",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,79",14
"low bq, bad alignment, many samples",UPN2_093,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2017,50,2072,"0,0241312741",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,68","14,7"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3436,77,3535,"0,0217821782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,69","15,08"
"low bq, many samples",UPN2_062,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4504,116,4647,"0,0249623413",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,12","14,4"
"low bq, bad alignment, many samples",UPN2_063,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3158,95,3267,"0,0290786654",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,7","14,15"
"low bq, bad alignment, many samples",UPN2_064,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2722,70,2811,"0,02490217",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,78","14,39"
"low bq, bad alignment, many samples",UPN2_066,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),676,21,701,"0,029957204",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,61","16,1"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_067,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1135,25,1174,"0,0212947189",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,44","14,28"
"low bq, many samples",UPN2_068,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1799,62,1872,"0,0331196581",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,16","14,21"
"low bq, bad alignment, many samples",UPN2_069,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2631,81,2730,"0,0296703297",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,4","15,1"
"low bq, bad alignment, many samples",UPN2_070,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1749,54,1811,"0,0298177802",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,87","14,87"
"low bq, bad alignment, many samples",UPN2_071,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4489,115,4632,"0,0248272884",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,76","15,13"
"low bq, bad alignment, many samples",UPN2_072,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5412,127,5575,"0,0227802691",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,73","14,94"
"low bq, bad alignment, many samples",UPN2_073,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2596,94,2703,"0,0347761746",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"25,92","14,64"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1216,25,1245,"0,0200803213",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,35",14
"low bq, bad alignment, many samples",UPN2_075,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4471,119,4609,"0,0258190497",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,49","14,11"
"low bq, bad alignment, many samples",UPN2_076,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2666,72,2752,"0,0261627907",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,66","15,75"
"low bq, bad alignment, many samples",UPN2_077,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2322,66,2405,"0,0274428274",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,72","14,82"
"low bq, many samples",UPN2_078,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3498,90,3608,"0,0249445676",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,12","14,43"
"low bq, many samples",UPN2_079,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1843,48,1902,"0,0252365931",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,07","15,17"
"low bq, bad alignment, many samples",UPN2_080,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5683,148,5858,"0,0252645954",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,91","14,74"
"low bq, bad alignment, many samples",UPN2_081,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),7441,223,7722,"0,0288785289",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"25,74","14,39"
"low bq, bad alignment, many samples",UPN2_082,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2233,63,2318,"0,0271786022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,59","14,81"
"low bq, bad alignment, many samples",UPN2_083,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3094,77,3191,"0,0241303667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,85","14,6"
"low bq, bad alignment, many samples",UPN2_084,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2914,96,3019,"0,0317986088",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,94","14,55"
"low bq, bad alignment, many samples",UPN2_085,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2028,55,2098,"0,0262154433",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,82","14,13"
"low bq, bad alignment, many samples",UPN2_086,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1128,35,1166,"0,0300171527",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,99","14,57"
"low bq, bad alignment, many samples",UPN2_087,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2446,63,2520,"0,025",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,81","14,35"
"low bq, bad alignment, many samples",UPN2_088,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1889,58,1962,"0,0295616718",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,67","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_094,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4146,90,4251,"0,0211714891",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,03","14,61"
"low bq, many samples",UPN2_095,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4256,104,4382,"0,023733455",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,47","14,13"
"low bq, bad alignment, many samples",UPN2_096,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4265,111,4402,"0,025215811",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,95","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_097,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4842,102,4963,"0,0205520854",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,16","14,54"
"low bq, bad alignment, many samples",UPN2_098,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3462,87,3573,"0,0243492863",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"25,83","14,23"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_099,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2111,46,2164,"0,0212569316",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,62","14,78"
"low bq, bad alignment, many samples",UPN2_100,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4461,111,4597,"0,0241461823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,8","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_101,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3871,82,3982,"0,020592667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,19","14,09"
"low bq, bad alignment, many samples",UPN2_102,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3592,84,3687,"0,0227827502",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,89","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_103,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4530,94,4652,"0,0202063629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,29","14,46"
"low bq, many samples",UPN2_104,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4786,137,4942,"0,0277215702",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,24",14
"low bq, low freq, many artifacts, many samples",UPN2_105,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4141,93,4259,"0,0218361118",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,25","14,65"
"low bq, bad alignment, many samples",UPN2_106,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5975,167,6176,"0,0270401554",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"25,86","14,16"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_107,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6312,134,6476,"0,0206917851",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,96","14,21"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_108,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6940,151,7128,"0,0211840629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"26,94","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_109,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6031,121,6176,"0,0195919689",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,29","14,46"
"low freq, many artifacts, many samples",UPN2_110,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6809,149,6976,"0,021358945",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,27,"14,52"
"low bq, low freq, many artifacts",UPN2_111,21,36206782,C,G,missense_variant(MODERATE|MISSENSE|Gcc/Ccc|p.Ala244Pro/c.730G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4858,104,4984,"0,0208667737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,302,Tolerated,"27,58","14,13"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_001,21,36206782,C,T,missense_variant(MODERATE|MISSENSE|Gcc/Acc|p.Ala244Thr/c.730G>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),1839,20,1896,"0,0105485232",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,536,Tolerated,"26,88",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_041,21,36206782,C,T,missense_variant(MODERATE|MISSENSE|Gcc/Acc|p.Ala244Thr/c.730G>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),6864,96,7234,"0,0132706663",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,536,Tolerated,"25,94","16,31"
"low bq, low freq, many artifacts, many samples",UPN2_036,21,36206782,C,T,missense_variant(MODERATE|MISSENSE|Gcc/Acc|p.Ala244Thr/c.730G>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),4419,48,4550,"0,0105494505",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,536,Tolerated,"27,19","22,73"
"low bq, low freq, many artifacts, many samples",UPN2_052,21,36206782,C,T,missense_variant(MODERATE|MISSENSE|Gcc/Acc|p.Ala244Thr/c.730G>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),5929,69,6164,"0,0111940299",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,536,Tolerated,"27,16","22,86"
"low bq, low freq, many artifacts, many samples",UPN2_011,21,36206782,C,T,missense_variant(MODERATE|MISSENSE|Gcc/Acc|p.Ala244Thr/c.730G>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),4545,54,4718,"0,0114455278",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,536,Tolerated,"27,23","16,87"
"low bq, bad alignment, low freq, many artifacts",UPN2_012,21,36206782,C,T,missense_variant(MODERATE|MISSENSE|Gcc/Acc|p.Ala244Thr/c.730G>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2447,29,2537,"0,0114308238",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,27",Neutral,536,Tolerated,"25,94","14,76"
"low bq, bad alignment, many samples",UPN2_003,21,36206787,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His242Pro/c.725A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),480,44,530,"0,0830188679",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,5,Damaging,"26,4","14,61"
"low bq, bad alignment, many samples",UPN2_041,21,36206787,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His242Pro/c.725A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6475,804,7298,"0,1101671691",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,5,Damaging,"26,38","15,01"
"low bq, bad alignment, many samples",UPN2_004,21,36206787,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His242Pro/c.725A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),326,35,365,"0,095890411",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,5,Damaging,"26,57","14,77"
"low bq, bad alignment, many samples",UPN2_049,21,36206787,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His242Pro/c.725A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6694,907,7651,"0,1185465952",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,5,Damaging,"26,41","14,86"
"low bq, bad alignment, many samples",UPN2_061,21,36206787,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His242Pro/c.725A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3222,297,3543,"0,083827265",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,5,Damaging,"26,08","15,38"
"low bq, bad alignment, many samples",UPN2_065,21,36206787,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His242Pro/c.725A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),477,53,532,"0,0996240602",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,5,Damaging,"24,91","15,26"
"low bq, bad alignment, many samples",UPN2_066,21,36206787,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His242Pro/c.725A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),649,49,706,"0,0694050992",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,5,Damaging,"25,51","14,45"
"low bq, bad alignment, many samples",UPN2_081,21,36206787,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His242Pro/c.725A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6851,845,7749,"0,1090463286",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,5,Damaging,"25,78","15,28"
"low bq, bad alignment",UPN2_086,21,36206787,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His242Pro/c.725A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1068,96,1166,"0,0823327616",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,53",Deleterious,5,Damaging,"25,96","15,15"
"inspected, many artifacts",UPN2_093,21,36206789,G,C,missense_variant(MODERATE|MISSENSE|caC/caG|p.His241Gln/c.723C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2035,34,2075,"0,0163855422",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,06",Neutral,"0,146",Tolerated,"31,91","30,68"
"low bq, bad alignment, many samples",UPN2_003,21,36206790,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His241Pro/c.722A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),493,39,532,"0,0733082707",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,251,Tolerated,"26,41","15,05"
"low bq, bad alignment, many samples",UPN2_004,21,36206790,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His241Pro/c.722A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),337,23,365,"0,0630136986",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,251,Tolerated,"26,59","14,87"
"low bq, bad alignment, many samples",UPN2_061,21,36206790,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His241Pro/c.722A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3154,380,3549,"0,1070724148",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,251,Tolerated,"26,16","15,01"
"low bq, bad alignment, many samples",UPN2_065,21,36206790,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His241Pro/c.722A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),466,65,533,"0,1219512195",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,251,Tolerated,"25,94","14,8"
"low bq, bad alignment, many samples",UPN2_066,21,36206790,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His241Pro/c.722A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),640,65,706,"0,0920679887",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,251,Tolerated,"26,1","14,6"
"low bq, bad alignment, many samples",UPN2_069,21,36206790,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His241Pro/c.722A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2430,316,2754,"0,1147421932",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,251,Tolerated,"26,18","15,32"
"low bq, bad alignment, many samples",UPN2_075,21,36206790,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His241Pro/c.722A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4110,480,4629,"0,1036941024",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,251,Tolerated,"26,41","15,34"
"low bq, bad alignment, many samples",UPN2_080,21,36206790,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His241Pro/c.722A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5326,531,5879,"0,0903214832",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,251,Tolerated,"26,44","15,09"
"low bq, bad alignment, many samples",UPN2_081,21,36206790,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His241Pro/c.722A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6866,851,7763,"0,1096225686",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,251,Tolerated,"25,89","15,07"
"low bq, bad alignment",UPN2_084,21,36206790,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His241Pro/c.722A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2687,320,3028,"0,105680317",0,0,0,0,0,1,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,47",Neutral,251,Tolerated,"26,32","14,98"
inspected,UPN2_092,21,36206795,G,GCTGAC,frameshift_variant(HIGH||agc/agGTCAGc|p.Ser239fs/c.712_716dupGTCAG|480|RUNX1|protein_coding|CODING|ENST00000437180|7|GCTGAC),1482,63,1489,"0,0423102754",0,0,0,1,1,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,83",NA
"low bq, low freq, many artifacts, many samples",UPN2_060,21,36206797,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser239Arg/c.715A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3341,39,3399,"0,0114739629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,9,Damaging,"29,56",14
"low bq, low freq, many artifacts, many samples",UPN2_061,21,36206797,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser239Arg/c.715A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3522,51,3580,"0,0142458101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,9,Damaging,"29,55","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_062,21,36206797,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser239Arg/c.715A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4624,47,4695,"0,0100106496",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,9,Damaging,"29,57","15,64"
"low bq, low freq, many artifacts, many samples",UPN2_064,21,36206797,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser239Arg/c.715A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2792,36,2849,"0,0126360126",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,9,Damaging,"29,59","15,78"
"low bq, low freq, many artifacts, many samples",UPN2_068,21,36206797,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser239Arg/c.715A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1851,34,1896,"0,0179324895",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,9,Damaging,"29,77","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_069,21,36206797,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser239Arg/c.715A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2723,35,2775,"0,0126126126",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,9,Damaging,"29,37","15,49"
"low bq, low freq, many artifacts, many samples",UPN2_070,21,36206797,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser239Arg/c.715A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1791,32,1829,"0,0174958994",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,9,Damaging,"29,52","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_072,21,36206797,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser239Arg/c.715A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5587,66,5664,"0,0116525424",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,9,Damaging,"29,57","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_075,21,36206797,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser239Arg/c.715A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4583,53,4656,"0,0113831615",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,9,Damaging,"29,93","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_078,21,36206797,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser239Arg/c.715A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3596,48,3650,"0,0131506849",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,9,Damaging,"29,66","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_079,21,36206797,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser239Arg/c.715A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1881,25,1923,"0,01300052",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,9,Damaging,"29,64","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_081,21,36206797,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser239Arg/c.715A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),7715,89,7849,"0,0113390241",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,9,Damaging,"29,69","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_082,21,36206797,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser239Arg/c.715A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2290,40,2346,"0,0170502984",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,9,Damaging,"29,62","15,95"
"low bq, low freq, many artifacts, many samples",UPN2_084,21,36206797,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser239Arg/c.715A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2995,31,3042,"0,010190664",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,9,Damaging,"29,89","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_087,21,36206797,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser239Arg/c.715A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2512,27,2547,"0,0106007067",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,9,Damaging,"29,96","15,81"
"low bq, low freq, many artifacts",UPN2_088,21,36206797,T,G,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser239Arg/c.715A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1948,25,1977,"0,0126454224",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,35",Neutral,9,Damaging,"29,51","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_001,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1927,31,1964,"0,0157841141",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"29,31","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_002,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2669,35,2722,"0,0128581925",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"28,83","14,2"
"low bq, many samples",UPN2_041,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),7279,172,7493,"0,0229547578",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"27,86","14,84"
"low bq, many samples",UPN2_089,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),3836,167,4016,"0,0415836653",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"28,22","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_042,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),9327,211,9623,"0,0219266341",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"27,81","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_043,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),5683,126,5870,"0,0214650767",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"27,93","14,67"
"low bq, many samples",UPN2_044,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2354,56,2428,"0,0230642504",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"28,02","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_045,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),6536,131,6730,"0,0194650817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"27,66","14,94"
"low bq, many samples",UPN2_046,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),7547,185,7784,"0,0237667009",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"27,86","15,07"
"low bq, many samples",UPN2_047,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),11121,258,11479,"0,0224758254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"27,78","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_048,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),7948,173,8195,"0,0211104332",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"27,96","14,66"
"low bq, many samples",UPN2_049,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),7639,178,7896,"0,0225430598",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"27,73","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_050,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),7546,162,7777,"0,0208306545",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"27,79","14,9"
"low bq, many samples",UPN2_051,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),7620,185,7857,"0,0235458827",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"27,82","15,02"
"low bq, many samples",UPN2_052,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),6127,146,6328,"0,0230720607",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"27,93","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_053,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),9580,206,9892,"0,020824909",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"27,81","15,43"
"low bq, many samples",UPN2_054,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),5325,126,5504,"0,0228924419",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"27,76","15,17"
"low bq, low freq, many artifacts, many samples",UPN2_007,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),6399,70,6514,"0,0107460854",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"29,11","15,93"
"low bq, low freq, many artifacts, many samples",UPN2_008,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),9685,119,9840,"0,0120934959",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"28,9","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_009,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),7775,100,7919,"0,0126278571",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"28,91","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_010,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),4053,50,4137,"0,0120860527",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"29,12","16,58"
"low bq, low freq, many artifacts, many samples",UPN2_011,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),4779,61,4870,"0,0125256674",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"28,94","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_055,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),9203,186,9469,"0,0196430457",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"27,79","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_056,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),3465,66,3566,"0,0185081324",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"27,98","14,47"
"low bq, many samples",UPN2_090,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2067,86,2165,"0,0397228637",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"28,26","14,69"
"low bq, many samples",UPN2_057,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),6017,160,6237,"0,025653359",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"27,78","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_058,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),5297,97,5457,"0,0177753344",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"27,72","15,15"
"low bq, bad alignment, many samples",UPN2_059,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1434,171,1615,"0,1058823529",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"26,87","15,74"
"low bq, low freq, many artifacts, many samples",UPN2_012,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2659,35,2708,"0,0129246677",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"29,07","14,71"
"low bq, bad alignment, many samples",UPN2_060,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),3020,355,3399,"0,1044424831",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"26,97","16,33"
"low bq, many samples",UPN2_091,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2864,120,2990,"0,0401337793",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"28,16","15,27"
"low bq, many samples",UPN2_093,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2003,71,2094,"0,0339063992",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"28,61","14,9"
"low bq, many samples, no database",UPN2_061,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),3200,363,3585,"0,1012552301",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"27,06","16,07"
"low bq, many samples, no database",UPN2_062,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),4191,484,4699,"0,1030006384",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"26,89","16,31"
"low bq, many samples, no database",UPN2_063,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2946,336,3309,"0,1015412511",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"26,97","15,95"
"low bq, bad alignment, many samples",UPN2_064,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2547,290,2851,"0,1017186952",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"26,86","15,74"
"low bq, many samples",UPN2_065,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),498,55,554,"0,0992779783",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"27,27","15,95"
"low bq, many samples",UPN2_066,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),642,64,713,"0,0897615708",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"27,3","16,11"
"low bq, bad alignment, many samples",UPN2_067,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1075,108,1191,"0,0906801008",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"26,66","15,34"
"low bq, many samples, no database",UPN2_068,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1664,221,1897,"0,1164997364",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"27,02","16,21"
"low bq, bad alignment, many samples",UPN2_069,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2454,299,2778,"0,1076313895",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"26,91","16,04"
"low bq, bad alignment, many samples",UPN2_070,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1637,182,1831,"0,0993992354",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"26,89","15,96"
"low bq, many samples",UPN2_071,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),4172,491,4698,"0,1045125585",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"27,41","15,7"
"low bq, many samples, no database",UPN2_072,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),5031,582,5665,"0,1027360989",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"26,91","15,71"
"low bq, many samples",UPN2_073,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2440,285,2741,"0,1039766509",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"27,27","15,72"
"low bq, many samples",UPN2_074,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1146,129,1283,"0,1005455963",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"27,19","15,92"
"low bq, many samples, no database",UPN2_075,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),4199,438,4660,"0,0939914163",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"27,07","15,96"
"low bq, many samples, no database",UPN2_076,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2476,300,2786,"0,1076812635",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"27,13","15,71"
"low bq, bad alignment, many samples",UPN2_077,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2154,262,2432,"0,1077302632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"26,73","16,04"
"low bq, bad alignment, many samples",UPN2_078,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),3217,398,3650,"0,1090410959",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"26,9","15,87"
"low bq, bad alignment, many samples",UPN2_079,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1711,208,1926,"0,1079958463",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"26,85","15,76"
"low bq, many samples, no database",UPN2_080,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),5280,595,5929,"0,1003541913",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"26,9","15,61"
"low bq, bad alignment, many samples",UPN2_081,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),7016,781,7864,"0,0993133266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"26,91","15,99"
"low bq, many samples",UPN2_082,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2098,231,2348,"0,0983816014",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"27,06","15,98"
"low bq, bad alignment, many samples",UPN2_083,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2921,344,3287,"0,1046547003",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"26,87","16,07"
"low bq, bad alignment, many samples",UPN2_084,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2687,340,3048,"0,1115485564",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"26,94","15,61"
"low bq, bad alignment, many samples",UPN2_085,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1889,223,2130,"0,1046948357",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"26,68","15,59"
"low bq, bad alignment, many samples",UPN2_086,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1057,114,1177,"0,0968564146",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"26,61","16,01"
"low bq, many samples",UPN2_087,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2266,262,2547,"0,102866117",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"27,16","15,94"
"low bq, many samples",UPN2_088,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1773,188,1977,"0,0950935761",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"27,02","16,24"
"low bq, many samples",UPN2_094,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),4123,159,4303,"0,0369509644",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"28,29","15,26"
"low bq, many samples",UPN2_095,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),4240,175,4430,"0,039503386",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"28,17","15,43"
"low bq, many samples",UPN2_096,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),4277,173,4472,"0,0386851521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"28,45","14,98"
"low bq, many samples",UPN2_097,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),4831,194,5039,"0,0384997023",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"28,28","14,98"
"low bq, many samples",UPN2_098,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),3522,111,3647,"0,0304359748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"28,27","15,24"
"low bq, many samples",UPN2_099,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2100,82,2191,"0,037425833",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"28,25","15,09"
"low bq, many samples",UPN2_100,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),4478,173,4666,"0,0370767252",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"28,32","15,05"
"low bq, many samples",UPN2_101,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),3911,126,4049,"0,0311187948",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"28,29","15,36"
"low bq, many samples",UPN2_102,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),3600,145,3752,"0,0386460554",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"28,1","15,2"
"low bq, many samples",UPN2_103,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),4511,174,4696,"0,0370528109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,28,"14,93"
"low bq, many samples",UPN2_104,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),4786,197,5010,"0,0393213573",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"28,21","14,99"
"low bq, many samples",UPN2_105,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),4154,154,4322,"0,035631652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"28,33","15,34"
"low bq, many samples",UPN2_106,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),6086,217,6322,"0,0343245808",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"28,23","15,24"
"low bq, many samples",UPN2_107,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),6287,254,6569,"0,0386664637",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"28,35","15,24"
"low bq, many samples",UPN2_108,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),6952,253,7233,"0,0349785704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"28,24","15,42"
"low bq, many samples",UPN2_109,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),5984,240,6254,"0,0383754397",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"28,18","15,45"
"low bq, many samples",UPN2_110,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),6809,250,7095,"0,0352360817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"28,3","14,9"
low bq,UPN2_111,21,36206799,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val238Gly/c.713T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),4836,203,5052,"0,0401821061",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,0,Damaging,"28,26","15,68"
"low bq, low freq, many artifacts, many samples",UPN2_063,21,36206800,C,G,missense_variant(MODERATE|MISSENSE|Gtc/Ctc|p.Val238Leu/c.712G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3254,36,3310,"0,0108761329",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,61,Tolerated,"29,11","15,17"
"low bq, low freq, many artifacts, many samples",UPN2_080,21,36206800,C,G,missense_variant(MODERATE|MISSENSE|Gtc/Ctc|p.Val238Leu/c.712G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5853,61,5930,"0,0102866779",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,67",Neutral,61,Tolerated,"29,45","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_059,21,36206801,C,G,missense_variant(MODERATE|MISSENSE|agG/agC|p.Arg237Ser/c.711G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1593,20,1615,"0,0123839009",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,41",Deleterious,2,Damaging,"28,65","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_060,21,36206801,C,G,missense_variant(MODERATE|MISSENSE|agG/agC|p.Arg237Ser/c.711G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3344,41,3401,"0,0120552779",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,41",Deleterious,2,Damaging,"28,81","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_063,21,36206801,C,G,missense_variant(MODERATE|MISSENSE|agG/agC|p.Arg237Ser/c.711G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3262,42,3310,"0,0126888218",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,41",Deleterious,2,Damaging,"28,59","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_069,21,36206801,C,G,missense_variant(MODERATE|MISSENSE|agG/agC|p.Arg237Ser/c.711G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2736,29,2778,"0,0104391649",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,41",Deleterious,2,Damaging,"28,52",14
"low bq, low freq, many artifacts, many samples",UPN2_070,21,36206801,C,G,missense_variant(MODERATE|MISSENSE|agG/agC|p.Arg237Ser/c.711G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1801,21,1832,"0,0114628821",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,41",Deleterious,2,Damaging,"28,76",14
"low bq, low freq, many artifacts, many samples",UPN2_072,21,36206801,C,G,missense_variant(MODERATE|MISSENSE|agG/agC|p.Arg237Ser/c.711G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5589,68,5666,"0,0120014119",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,41",Deleterious,2,Damaging,"28,46","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_073,21,36206801,C,G,missense_variant(MODERATE|MISSENSE|agG/agC|p.Arg237Ser/c.711G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2693,33,2743,"0,0120306234",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,41",Deleterious,2,Damaging,"28,82","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_080,21,36206801,C,G,missense_variant(MODERATE|MISSENSE|agG/agC|p.Arg237Ser/c.711G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5854,63,5931,"0,0106221548",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,41",Deleterious,2,Damaging,"28,69","14,11"
"low bq, low freq, many artifacts, many samples",UPN2_082,21,36206801,C,G,missense_variant(MODERATE|MISSENSE|agG/agC|p.Arg237Ser/c.711G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2316,25,2350,"0,0106382979",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,41",Deleterious,2,Damaging,"28,51",14
"low bq, low freq, many artifacts",UPN2_083,21,36206801,C,G,missense_variant(MODERATE|MISSENSE|agG/agC|p.Arg237Ser/c.711G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3238,37,3287,"0,0112564649",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,41",Deleterious,2,Damaging,"28,77","14,35"
"low bq, many samples",UPN2_059,21,36206805,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met236Arg/c.707T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1569,40,1616,"0,0247524752",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,21",Deleterious,1,Damaging,"29,48","15,85"
"low bq, low freq, many artifacts, many samples",UPN2_060,21,36206805,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met236Arg/c.707T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),3321,63,3402,"0,0185185185",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,21",Deleterious,1,Damaging,"29,3","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_061,21,36206805,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met236Arg/c.707T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),3480,71,3585,"0,019804742",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,21",Deleterious,1,Damaging,"29,29","16,18"
"low bq, low freq, many artifacts, many samples",UPN2_062,21,36206805,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met236Arg/c.707T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),4554,102,4700,"0,0217021277",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,21",Deleterious,1,Damaging,"29,08","15,95"
"low bq, low freq, many artifacts, many samples",UPN2_063,21,36206805,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met236Arg/c.707T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),3222,67,3312,"0,0202294686",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,21",Deleterious,1,Damaging,"29,11","15,51"
"low bq, low freq, many artifacts, many samples",UPN2_064,21,36206805,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met236Arg/c.707T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2782,47,2853,"0,0164738871",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,21",Deleterious,1,Damaging,"29,04","15,49"
"low bq, low freq, many artifacts, many samples",UPN2_067,21,36206805,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met236Arg/c.707T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1163,21,1192,"0,0176174497",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,21",Deleterious,1,Damaging,"29,78","15,81"
"low bq, many samples",UPN2_068,21,36206805,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met236Arg/c.707T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1846,43,1898,"0,0226554268",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,21",Deleterious,1,Damaging,"29,12","14,72"
"low bq, many samples",UPN2_069,21,36206805,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met236Arg/c.707T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2696,63,2779,"0,0226700252",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,21",Deleterious,1,Damaging,"29,41","15,02"
"low bq, many samples",UPN2_070,21,36206805,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met236Arg/c.707T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1783,42,1833,"0,022913257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,21",Deleterious,1,Damaging,"28,78","14,74"
"low bq, many samples",UPN2_071,21,36206805,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met236Arg/c.707T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),4562,107,4699,"0,0227708023",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,21",Deleterious,1,Damaging,"29,44","15,34"
"low bq, many samples",UPN2_072,21,36206805,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met236Arg/c.707T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),5489,134,5669,"0,0236373258",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,21",Deleterious,1,Damaging,"29,1","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_073,21,36206805,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met236Arg/c.707T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2673,52,2744,"0,0189504373",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,21",Deleterious,1,Damaging,"29,66","15,48"
"low bq, low freq, many artifacts, many samples",UPN2_074,21,36206805,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met236Arg/c.707T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1247,26,1284,"0,0202492212",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,21",Deleterious,1,Damaging,"29,88","16,04"
"low bq, low freq, many artifacts, many samples",UPN2_075,21,36206805,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met236Arg/c.707T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),4538,83,4664,"0,0177958834",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,21",Deleterious,1,Damaging,"29,61","16,18"
"low bq, many samples",UPN2_076,21,36206805,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met236Arg/c.707T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2703,62,2786,"0,0222541278",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,21",Deleterious,1,Damaging,"29,07","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_077,21,36206805,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met236Arg/c.707T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2367,51,2433,"0,0209617756",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,21",Deleterious,1,Damaging,"29,64","15,61"
"low bq, many samples",UPN2_078,21,36206805,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met236Arg/c.707T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),3541,88,3652,"0,0240963855",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,21",Deleterious,1,Damaging,"29,37","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_079,21,36206805,A,C,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met236Lys/c.707T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),1851,31,1929,"0,0160705029",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,21",Deleterious,1,Damaging,"29,2","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_080,21,36206805,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met236Arg/c.707T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),5769,122,5932,"0,0205664194",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,21",Deleterious,1,Damaging,"29,19","14,75"
"low bq, many samples",UPN2_081,21,36206805,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met236Arg/c.707T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),7612,185,7871,"0,023504002",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,21",Deleterious,1,Damaging,"29,38","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_082,21,36206805,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met236Arg/c.707T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2295,48,2354,"0,0203908241",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,21",Deleterious,1,Damaging,"29,4","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_083,21,36206805,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met236Arg/c.707T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),3200,69,3289,"0,020979021",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,21",Deleterious,1,Damaging,"29,14","14,77"
"low bq, many samples",UPN2_084,21,36206805,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met236Arg/c.707T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2962,69,3050,"0,0226229508",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,21",Deleterious,1,Damaging,"29,14","15,58"
"low bq, many samples",UPN2_085,21,36206805,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met236Arg/c.707T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2067,47,2131,"0,0220553731",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,21",Deleterious,1,Damaging,"29,31","15,34"
"low bq, many samples",UPN2_086,21,36206805,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met236Arg/c.707T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1139,32,1178,"0,0271646859",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,21",Deleterious,1,Damaging,"29,05","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_087,21,36206805,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met236Arg/c.707T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2465,56,2548,"0,021978022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,21",Deleterious,1,Damaging,"29,29","15,48"
low bq,UPN2_088,21,36206805,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met236Arg/c.707T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1923,46,1977,"0,0232675771",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,21",Deleterious,1,Damaging,"29,61","15,35"
"inspected, many artifacts",UPN2_090,21,36206805,A,G,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met236Thr/c.707T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2125,26,2166,"0,0120036934",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,"0,003",Damaging,"32,23","34,38"
"inspected, many artifacts",UPN2_079,21,36206805,A,G,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met236Arg/c.707T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1851,22,1929,"0,011404873",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,86",Deleterious,"0,003",Damaging,"29,2",31
"low bq, low freq, many artifacts",UPN2_041,21,36206805,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met236Lys/c.707T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),7357,79,7499,"0,010534738",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,12",Deleterious,1,Damaging,"31,61","22,52"
"inspected, many artifacts",UPN2_079,21,36206805,A,T,missense_variant(MODERATE|MISSENSE|aTg/aCg|p.Met236Thr/c.707T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1851,25,1929,"0,0129600829",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,12",Deleterious,"0,001",Damaging,"29,2",26
"low bq, low freq, many artifacts",UPN2_084,21,36206812,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr234Pro/c.700A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2981,41,3051,"0,013438217",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,06",Neutral,496,Tolerated,"30,86","18,17"
"inspected, many artifacts, many samples",UPN2_002,21,36206815,G,A,missense_variant(MODERATE|MISSENSE|Cgc/Tgc|p.Arg233Cys/c.697C>T|480|RUNX1|protein_coding|CODING|ENST00000437180|7|A),2745,56,2801,"0,0199928597",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,42",Deleterious,"0,013",Damaging,"33,03","34,91"
"inspected, many artifacts, many samples",UPN2_089,21,36206815,G,A,missense_variant(MODERATE|MISSENSE|Cgc/Tgc|p.Arg233Cys/c.697C>T|480|RUNX1|protein_coding|CODING|ENST00000437180|7|A),3999,60,4066,"0,0147565175",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,42",Deleterious,"0,013",Damaging,"32,5","34,6"
"inspected, many artifacts, many samples",UPN2_090,21,36206815,G,A,missense_variant(MODERATE|MISSENSE|Cgc/Tgc|p.Arg233Cys/c.697C>T|480|RUNX1|protein_coding|CODING|ENST00000437180|7|A),2163,69,2236,"0,0308586762",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,42",Deleterious,"0,013",Damaging,"32,49","35,88"
"inspected, many artifacts, many samples",UPN2_058,21,36206815,G,A,missense_variant(MODERATE|MISSENSE|Cgc/Tgc|p.Arg233Cys/c.697C>T|480|RUNX1|protein_coding|CODING|ENST00000437180|7|A),5403,56,5468,"0,0102414045",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,42",Deleterious,"0,013",Damaging,"31,78","26,89"
"inspected, many artifacts, many samples",UPN2_013,21,36206815,G,A,missense_variant(MODERATE|MISSENSE|Cgc/Tgc|p.Arg233Cys/c.697C>T|480|RUNX1|protein_coding|CODING|ENST00000437180|7|A),1730,65,1796,"0,0361915367",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,42",Deleterious,"0,013",Damaging,"33,16","34,77"
"inspected, many artifacts, many samples",UPN2_061,21,36206815,G,A,missense_variant(MODERATE|MISSENSE|Cgc/Tgc|p.Arg233Cys/c.697C>T|480|RUNX1|protein_coding|CODING|ENST00000437180|7|A),3584,156,3744,"0,0416666667",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,42",Deleterious,"0,013",Damaging,"31,98","34,88"
"inspected, many artifacts, many samples",UPN2_085,21,36206815,G,A,missense_variant(MODERATE|MISSENSE|Cgc/Tgc|p.Arg233Cys/c.697C>T|480|RUNX1|protein_coding|CODING|ENST00000437180|7|A),2117,50,2169,"0,0230520977",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,42",Deleterious,"0,013",Damaging,"32,19","32,76"
"inspected, many artifacts, many samples",UPN2_098,21,36206815,G,A,missense_variant(MODERATE|MISSENSE|Cgc/Tgc|p.Arg233Cys/c.697C>T|480|RUNX1|protein_coding|CODING|ENST00000437180|7|A),3637,40,3680,"0,0108695652",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-3,42",Deleterious,"0,013",Damaging,"32,4","35,12"
"inspected, many artifacts",UPN2_079,21,36206817,C,T,missense_variant(MODERATE|MISSENSE|cGg/cAg|p.Arg232Gln/c.695G>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),1898,20,1929,"0,0103680664",0,0,0,0,1,0,0,1,2,"0,0116",NO,NO,NA,NA,NO,rs368711448,NO,NA,NO,NO,"-1,76",Neutral,"0,185",Tolerated,"30,39","30,35"
"low bq, low freq, many artifacts, many samples",UPN2_059,21,36206820,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu231Arg/c.692T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1569,35,1618,"0,021631644",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,55","17,54"
"low bq, low freq, many artifacts, many samples",UPN2_060,21,36206820,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu231Arg/c.692T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),3331,67,3420,"0,0195906433",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,30,"15,21"
"low bq, low freq, many artifacts, many samples",UPN2_092,21,36206820,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu231Arg/c.692T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1465,23,1498,"0,0153538051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"31,46","16,22"
"low bq, many samples",UPN2_061,21,36206820,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu231Arg/c.692T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),3632,91,3743,"0,0243120492",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,92","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_062,21,36206820,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu231Arg/c.692T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),4577,102,4703,"0,0216882841",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,65","14,8"
"low bq, many samples",UPN2_063,21,36206820,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu231Arg/c.692T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),3218,76,3313,"0,0229399336",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,83","15,12"
"low bq, many samples",UPN2_064,21,36206820,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu231Arg/c.692T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2760,76,2853,"0,026638626",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,4","14,43"
"low bq, many samples",UPN2_066,21,36206820,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu231Arg/c.692T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),690,20,713,"0,0280504909",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"30,31","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_067,21,36206820,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu231Arg/c.692T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1153,26,1191,"0,0218303946",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"30,37",15
"low bq, many samples",UPN2_068,21,36206820,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu231Arg/c.692T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1839,48,1899,"0,0252764613",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,71","14,15"
"low bq, many samples",UPN2_069,21,36206820,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu231Arg/c.692T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2691,73,2778,"0,0262778978",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"30,04","15,49"
"low bq, many samples",UPN2_070,21,36206820,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu231Arg/c.692T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1755,53,1830,"0,0289617486",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,8","15,23"
"low bq, many samples",UPN2_071,21,36206820,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu231Arg/c.692T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),4558,105,4699,"0,0223451798",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,91","15,15"
"low bq, many samples",UPN2_072,21,36206820,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu231Arg/c.692T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),5512,130,5673,"0,022915565",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,45","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_073,21,36206820,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu231Arg/c.692T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2666,51,2745,"0,018579235",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,67","14,86"
"low bq, many samples",UPN2_074,21,36206820,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu231Arg/c.692T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1250,30,1285,"0,0233463035",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,63","14,23"
"low bq, low freq, many artifacts, many samples",UPN2_075,21,36206820,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu231Arg/c.692T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),4533,99,4666,"0,0212173168",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"30,05","15,1"
"low bq, many samples",UPN2_076,21,36206820,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu231Arg/c.692T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2712,65,2789,"0,0233058444",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,93","15,22"
"low bq, many samples",UPN2_077,21,36206820,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu231Arg/c.692T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2359,55,2433,"0,0226058364",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,84","15,2"
"low bq, many samples",UPN2_078,21,36206820,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu231Arg/c.692T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),3530,92,3655,"0,0251709986",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,67",15
"low bq, low freq, many artifacts, many samples",UPN2_079,21,36206820,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu231Arg/c.692T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1875,41,1928,"0,0212655602",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,82","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_080,21,36206820,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu231Arg/c.692T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),5755,126,5934,"0,0212335693",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,76","15,12"
"low bq, many samples",UPN2_081,21,36206820,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu231Arg/c.692T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),7599,204,7871,"0,0259179266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,82","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_082,21,36206820,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu231Arg/c.692T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2296,36,2352,"0,0153061224",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,68","15,11"
"low bq, many samples",UPN2_083,21,36206820,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu231Arg/c.692T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),3188,81,3288,"0,0246350365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,88","14,09"
"low bq, many samples",UPN2_084,21,36206820,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu231Arg/c.692T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2963,71,3050,"0,0232786885",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,86","14,37"
"low bq, many samples",UPN2_085,21,36206820,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu231Arg/c.692T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2105,50,2167,"0,0230733733",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,79","14,78"
"low bq, many samples",UPN2_086,21,36206820,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu231Arg/c.692T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1142,32,1179,"0,0271416455",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,83","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_087,21,36206820,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu231Arg/c.692T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),2480,51,2550,"0,02",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,84","17,29"
"low bq, low freq, many artifacts",UPN2_088,21,36206820,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu231Arg/c.692T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),1920,43,1979,"0,0217281455",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,67",Deleterious,3,Damaging,"29,72","17,05"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_089,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3933,63,4000,"0,01575",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"26,84",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_090,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2160,35,2201,"0,0159018628",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"26,87",14
"low bq, bad alignment, many samples",UPN2_059,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1506,97,1609,"0,0602858919",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"25,74","14,26"
"low bq, bad alignment, many samples",UPN2_060,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3157,204,3372,"0,0604982206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"26,01","14,12"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_091,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2903,31,2958,"0,0104800541",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"26,42",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_092,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1416,25,1442,"0,0173370319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"26,8","16,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_093,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2021,24,2048,"0,01171875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"26,96",14
"low bq, bad alignment, many samples",UPN2_061,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3469,224,3700,"0,0605405405",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"26,28","14,09"
"low bq, bad alignment, many samples",UPN2_062,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4331,304,4644,"0,0654608096",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"25,87","14,24"
"low bq, bad alignment, many samples",UPN2_063,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3072,188,3262,"0,0576333538",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"25,83","14,13"
"low bq, bad alignment, many samples",UPN2_064,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2643,178,2823,"0,0630534892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"25,77","14,2"
"low bq, bad alignment, many samples",UPN2_065,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),512,27,543,"0,0497237569",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"26,69",14
"low bq, bad alignment, many samples",UPN2_066,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),657,43,702,"0,0612535613",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"26,22",14
"low bq, bad alignment, many samples",UPN2_067,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1113,59,1172,"0,0503412969",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"26,09",14
"low bq, bad alignment, many samples",UPN2_068,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1765,108,1880,"0,0574468085",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"25,74","14,29"
"low bq, bad alignment, many samples",UPN2_069,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2546,182,2734,"0,0665691295",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"25,98",14
"low bq, bad alignment, many samples",UPN2_070,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1695,120,1816,"0,0660792952",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"25,83","14,23"
"low bq, bad alignment, many samples",UPN2_071,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4353,291,4654,"0,0625268586",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"25,99","14,11"
"low bq, bad alignment, many samples",UPN2_072,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5222,353,5591,"0,0631371848",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"26,05","14,06"
"low bq, bad alignment, many samples",UPN2_073,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2577,154,2734,"0,0563277249",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"25,82","14,08"
"low bq, bad alignment, many samples",UPN2_074,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1189,82,1273,"0,0644147683",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"26,1","14,22"
"low bq, bad alignment, many samples",UPN2_075,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4358,243,4608,"0,052734375",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,26,"14,22"
"low bq, bad alignment, many samples",UPN2_076,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2604,173,2782,"0,0621854781",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"26,08","14,04"
"low bq, bad alignment, many samples",UPN2_077,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2244,152,2402,"0,0632805995",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"26,04",14
"low bq, bad alignment, many samples",UPN2_078,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3372,233,3617,"0,064418026",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"26,09","14,11"
"low bq, bad alignment, many samples",UPN2_079,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1772,135,1911,"0,0706436421",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"26,06","14,19"
"low bq, bad alignment, many samples",UPN2_080,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5493,351,5853,"0,0599692465",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"25,94","14,15"
"low bq, bad alignment, many samples",UPN2_081,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),7291,491,7800,"0,0629487179",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"25,9","14,05"
"low bq, bad alignment, many samples",UPN2_082,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2191,153,2347,"0,0651896037",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"25,75","14,08"
"low bq, bad alignment, many samples",UPN2_083,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3061,193,3262,"0,0591661557",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"26,18",14
"low bq, bad alignment, many samples",UPN2_084,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2845,191,3037,"0,0628910109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"26,08","14,1"
"low bq, bad alignment, many samples",UPN2_085,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1976,144,2123,"0,0678285445",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"26,27","14,14"
"low bq, bad alignment, many samples",UPN2_086,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1070,85,1162,"0,0731497418",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"26,11",14
"low bq, bad alignment, many samples",UPN2_087,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2373,134,2512,"0,053343949",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"25,86",14
"low bq, bad alignment, many samples",UPN2_088,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1834,128,1967,"0,0650737163",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"25,88","14,31"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_094,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4174,80,4258,"0,0187881635",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"26,66","14,25"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_095,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4308,79,4393,"0,017983155",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"26,59",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_096,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4334,84,4428,"0,0189701897",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"26,63","14,15"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_097,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4873,97,4977,"0,0194896524",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"26,63",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_098,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3548,70,3636,"0,0192519252",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"26,74","14,5"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_099,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2130,28,2159,"0,0129689671",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"26,64",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_100,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4574,55,4632,"0,0118739206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"26,48",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_101,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3937,78,4028,"0,0193644489",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"26,57","14,17"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_102,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3651,70,3739,"0,0187215833",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"26,62",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_103,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4583,67,4666,"0,0143591942",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"26,64",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_104,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4866,88,4959,"0,0177455132",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"26,82",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_105,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4181,93,4279,"0,02173405",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"26,8","14,24"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_106,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6136,113,6258,"0,0180568872",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"26,65",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_107,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6386,101,6497,"0,0155456364",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"26,66",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_108,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),7041,105,7157,"0,0146709515",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"26,64",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_109,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6086,93,6200,"0,015",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"26,6",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_110,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6901,116,7030,"0,0165007112",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"26,69",14
"low bq, bad alignment, low freq, many artifacts",UPN2_111,21,36206825,C,G,missense_variant(MODERATE|MISSENSE|gaG/gaC|p.Glu229Asp/c.687G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4938,78,5027,"0,0155162125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,89",Neutral,139,Tolerated,"26,59","14,26"
"low bq, low freq, many artifacts, many samples",UPN2_014,21,36206826,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu229Ala/c.686A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2137,28,2178,"0,012855831",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,34,Damaging,"33,05","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_015,21,36206826,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu229Ala/c.686A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3224,36,3282,"0,0109689214",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,34,Damaging,"33,33","17,14"
"low bq, low freq, many artifacts, many samples",UPN2_021,21,36206826,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu229Ala/c.686A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1553,23,1581,"0,0145477546",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,34,Damaging,"33,55","16,65"
"low bq, low freq, many artifacts, many samples",UPN2_022,21,36206826,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu229Ala/c.686A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2014,25,2041,"0,0122488976",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,34,Damaging,"33,12","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_023,21,36206826,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu229Ala/c.686A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2493,31,2536,"0,0122239748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,34,Damaging,"33,02","17,45"
"low bq, low freq, many artifacts, many samples",UPN2_041,21,36206826,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu229Ala/c.686A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3817,41,3875,"0,0105806452",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,34,Damaging,"32,32","15,98"
"low bq, low freq, many artifacts, many samples",UPN2_026,21,36206826,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu229Ala/c.686A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2853,32,2897,"0,0110459096",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,34,Damaging,"33,32","16,09"
"low bq, low freq, many artifacts, many samples",UPN2_027,21,36206826,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu229Ala/c.686A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2631,36,2677,"0,0134478894",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,34,Damaging,"33,07","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_042,21,36206826,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu229Ala/c.686A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4918,57,4995,"0,0114114114",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,34,Damaging,"32,3","15,82"
"low bq, low freq, many artifacts, many samples",UPN2_030,21,36206826,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu229Ala/c.686A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2410,25,2442,"0,0102375102",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,34,Damaging,"33,32","17,84"
"low bq, low freq, many artifacts, many samples",UPN2_046,21,36206826,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu229Ala/c.686A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3956,53,4036,"0,0131318137",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,34,Damaging,"32,68","16,87"
"low bq, low freq, many artifacts, many samples",UPN2_047,21,36206826,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu229Ala/c.686A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5971,69,6082,"0,0113449523",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,34,Damaging,"31,99","15,93"
"low bq, low freq, many artifacts, many samples",UPN2_048,21,36206826,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu229Ala/c.686A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4191,55,4272,"0,0128745318",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,34,Damaging,"32,36","15,76"
"low bq, low freq, many artifacts, many samples",UPN2_037,21,36206826,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu229Ala/c.686A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3994,47,4065,"0,0115621156",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,34,Damaging,"33,38","16,38"
"low bq, low freq, many artifacts, many samples",UPN2_052,21,36206826,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu229Ala/c.686A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3221,33,3280,"0,0100609756",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,34,Damaging,"32,17","15,61"
"low bq, low freq, many artifacts, many samples",UPN2_039,21,36206826,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu229Ala/c.686A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4387,57,4466,"0,012763099",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,34,Damaging,"33,35","16,82"
"low bq, low freq, many artifacts, many samples",UPN2_060,21,36206826,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu229Ala/c.686A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1734,35,1774,"0,019729425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,34,Damaging,"31,62","18,49"
"low bq, low freq, many artifacts, many samples",UPN2_061,21,36206826,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu229Ala/c.686A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1955,40,2002,"0,01998002",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,34,Damaging,"31,99","17,45"
"low bq, low freq, many artifacts, many samples",UPN2_062,21,36206826,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu229Ala/c.686A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2363,35,2408,"0,0145348837",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,34,Damaging,"32,12","18,4"
"low bq, low freq, many artifacts, many samples",UPN2_063,21,36206826,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu229Ala/c.686A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1660,27,1693,"0,0159480213",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,34,Damaging,"32,11","17,89"
"low bq, low freq, many artifacts, many samples",UPN2_064,21,36206826,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu229Ala/c.686A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1436,30,1468,"0,0204359673",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,34,Damaging,"32,03","17,23"
"low bq, low freq, many artifacts, many samples",UPN2_068,21,36206826,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu229Ala/c.686A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),942,21,967,"0,0217166494",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,34,Damaging,"31,89",18
"low bq, many samples",UPN2_069,21,36206826,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu229Ala/c.686A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1400,37,1442,"0,0256588072",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,34,Damaging,"31,72",18
"low bq, low freq, many artifacts, many samples",UPN2_071,21,36206826,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu229Ala/c.686A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2386,52,2444,"0,0212765957",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,34,Damaging,"31,88","18,02"
"low bq, low freq, many artifacts, many samples",UPN2_072,21,36206826,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu229Ala/c.686A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2837,49,2902,"0,016884907",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,34,Damaging,"31,74","17,92"
"low bq, low freq, many artifacts, many samples",UPN2_073,21,36206826,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu229Ala/c.686A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1374,22,1401,"0,0157030692",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,34,Damaging,"32,44","16,82"
"low bq, low freq, many artifacts, many samples",UPN2_075,21,36206826,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu229Ala/c.686A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2365,46,2420,"0,0190082645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,34,Damaging,"32,02","18,24"
"low bq, low freq, many artifacts, many samples",UPN2_076,21,36206826,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu229Ala/c.686A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1416,21,1438,"0,0146036161",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,34,Damaging,"31,8","15,48"
"low bq, low freq, many artifacts, many samples",UPN2_077,21,36206826,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu229Ala/c.686A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1238,21,1265,"0,0166007905",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,34,Damaging,"31,95","21,38"
"low bq, low freq, many artifacts, many samples",UPN2_078,21,36206826,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu229Ala/c.686A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1838,29,1874,"0,01547492",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,34,Damaging,"31,77","17,86"
"low bq, many samples",UPN2_079,21,36206826,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu229Ala/c.686A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),972,24,1000,"0,024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,34,Damaging,"31,73","17,96"
"low bq, many samples",UPN2_080,21,36206826,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu229Ala/c.686A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2988,69,3072,"0,0224609375",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,34,Damaging,"31,86","18,55"
"low bq, low freq, many artifacts, many samples",UPN2_081,21,36206826,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu229Ala/c.686A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3952,59,4025,"0,0146583851",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,34,Damaging,"32,12","19,42"
"low bq, low freq, many artifacts, many samples",UPN2_082,21,36206826,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu229Ala/c.686A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1174,21,1202,"0,0174708819",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,34,Damaging,"32,24","18,1"
"low bq, many samples",UPN2_083,21,36206826,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu229Ala/c.686A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1719,53,1777,"0,0298255487",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,34,Damaging,"31,43","19,49"
"low bq, many samples",UPN2_084,21,36206826,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu229Ala/c.686A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1551,49,1604,"0,0305486284",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,34,Damaging,"31,63","20,31"
"low bq, low freq, many artifacts, many samples",UPN2_087,21,36206826,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu229Ala/c.686A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1297,21,1321,"0,0158970477",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,34,Damaging,"31,9","16,19"
"low bq, low freq, many artifacts",UPN2_105,21,36206826,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu229Ala/c.686A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2240,24,2266,"0,0105913504",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,67",Deleterious,34,Damaging,"33,03","15,62"
"low bq, low freq, many artifacts, many samples",UPN2_014,21,36206829,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu228Gln/c.683T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2034,21,2062,"0,0101842871",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,18",Deleterious,0,Damaging,"34,32","18,19"
"low bq, low freq, many artifacts, many samples",UPN2_015,21,36206829,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu228Gln/c.683T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3098,42,3149,"0,0133375675",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,18",Deleterious,0,Damaging,"34,4","21,64"
"low bq, low freq, many artifacts, many samples",UPN2_023,21,36206829,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu228Gln/c.683T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2407,30,2444,"0,0122749591",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,18",Deleterious,0,Damaging,"34,24","18,3"
"low bq, low freq, many artifacts, many samples",UPN2_041,21,36206829,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu228Gln/c.683T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3657,55,3730,"0,0147453083",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,18",Deleterious,0,Damaging,"33,66","18,98"
"low bq, low freq, many artifacts, many samples",UPN2_026,21,36206829,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu228Gln/c.683T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2707,36,2752,"0,0130813953",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,18",Deleterious,0,Damaging,"34,6","19,61"
"low bq, low freq, many artifacts, many samples",UPN2_042,21,36206829,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu228Gln/c.683T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),4696,58,4783,"0,0121262806",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,18",Deleterious,0,Damaging,"33,72","19,66"
"low bq, low freq, many artifacts, many samples",UPN2_043,21,36206829,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu228Gln/c.683T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2860,36,2912,"0,0123626374",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,18",Deleterious,0,Damaging,"33,93","22,33"
"low bq, low freq, many artifacts, many samples",UPN2_045,21,36206829,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu228Gln/c.683T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3303,51,3367,"0,0151470151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,18",Deleterious,0,Damaging,"33,77","17,51"
"low bq, low freq, many artifacts, many samples",UPN2_046,21,36206829,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu228Gln/c.683T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3825,43,3878,"0,0110881898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,18",Deleterious,0,Damaging,"33,69","20,93"
"low bq, low freq, many artifacts, many samples",UPN2_047,21,36206829,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu228Gln/c.683T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),5648,76,5746,"0,0132265924",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,18",Deleterious,0,Damaging,"33,86","16,7"
"low bq, low freq, many artifacts, many samples",UPN2_048,21,36206829,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu228Gln/c.683T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),4019,46,4073,"0,0112938866",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,18",Deleterious,0,Damaging,"33,71","19,5"
"low bq, low freq, many artifacts, many samples",UPN2_035,21,36206829,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu228Gln/c.683T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2982,32,3027,"0,010571523",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,18",Deleterious,0,Damaging,"34,46","15,59"
"low bq, low freq, many artifacts, many samples",UPN2_036,21,36206829,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu228Gln/c.683T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2356,24,2396,"0,0100166945",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,18",Deleterious,0,Damaging,"34,52","19,79"
"low bq, low freq, many artifacts, many samples",UPN2_050,21,36206829,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu228Gln/c.683T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3803,47,3863,"0,0121667098",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,18",Deleterious,0,Damaging,"33,66","17,11"
"low bq, low freq, many artifacts, many samples",UPN2_051,21,36206829,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu228Gln/c.683T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3835,42,3898,"0,0107747563",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,18",Deleterious,0,Damaging,"33,9","18,17"
"low bq, low freq, many artifacts, many samples",UPN2_052,21,36206829,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu228Gln/c.683T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3092,39,3145,"0,0124006359",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,18",Deleterious,0,Damaging,"33,95","17,72"
"low bq, low freq, many artifacts, many samples",UPN2_039,21,36206829,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu228Gln/c.683T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),4225,43,4281,"0,0100443822",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,18",Deleterious,0,Damaging,"34,65","21,84"
"low bq, low freq, many artifacts, many samples",UPN2_054,21,36206829,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu228Gln/c.683T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2682,40,2732,"0,0146412884",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,18",Deleterious,0,Damaging,"33,76","18,3"
"low bq, low freq, many artifacts, many samples",UPN2_007,21,36206829,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu228Gln/c.683T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3265,34,3309,"0,0102750076",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,18",Deleterious,0,Damaging,"34,04","19,59"
"low bq, low freq, many artifacts, many samples",UPN2_011,21,36206829,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu228Gln/c.683T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2410,31,2448,"0,0126633987",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,18",Deleterious,0,Damaging,"34,14","16,77"
"low bq, low freq, many artifacts, many samples",UPN2_055,21,36206829,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu228Gln/c.683T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),4676,53,4744,"0,0111720067",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,18",Deleterious,0,Damaging,"33,98","17,06"
"low bq, low freq, many artifacts, many samples",UPN2_056,21,36206829,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu228Gln/c.683T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),1739,24,1772,"0,0135440181",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,18",Deleterious,0,Damaging,"33,76","17,5"
"low bq, low freq, many artifacts, many samples",UPN2_057,21,36206829,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu228Gln/c.683T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3057,33,3101,"0,0106417285",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,18",Deleterious,0,Damaging,"33,99","19,97"
"low bq, low freq, many artifacts, many samples",UPN2_058,21,36206829,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu228Gln/c.683T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2676,30,2715,"0,0110497238",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,18",Deleterious,0,Damaging,"33,94","19,37"
"low freq, many artifacts, many samples",UPN2_063,21,36206829,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu228Gln/c.683T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),1620,20,1647,"0,0121432908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,18",Deleterious,0,Damaging,"34,03",27
"low bq, low freq, many artifacts",UPN2_071,21,36206829,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu228Gln/c.683T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2297,26,2336,"0,011130137",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,18",Deleterious,0,Damaging,"34,01","22,62"
"inspected, many artifacts",UPN2_044,21,36206833,C,T,missense_variant(MODERATE|MISSENSE|Gaa/Aaa|p.Glu227Lys/c.679G>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),1171,29,1208,"0,0240066225",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,59",Deleterious,"0,006",Damaging,"33,44","34,34"
"inspected, many artifacts",UPN2_011,21,36206833,C,T,missense_variant(MODERATE|MISSENSE|Gaa/Aaa|p.Glu227Lys/c.679G>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2417,27,2449,"0,0110249081",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,59",Deleterious,"0,006",Damaging,"34,47","35,85"
"low bq, low freq, many artifacts, many samples",UPN2_018,21,36206834,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser226Arg/c.678T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),1818,27,1852,"0,0145788337",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,96",Deleterious,15,Damaging,"34,24","18,74"
"low bq, low freq, many artifacts, many samples",UPN2_023,21,36206834,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser226Arg/c.678T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2403,27,2444,"0,0110474632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,96",Deleterious,15,Damaging,"34,43","23,63"
"low bq, low freq, many artifacts, many samples",UPN2_041,21,36206834,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser226Arg/c.678T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3661,49,3730,"0,0131367292",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,96",Deleterious,15,Damaging,"33,41","19,67"
"low bq, low freq, many artifacts, many samples",UPN2_025,21,36206834,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser226Arg/c.678T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2480,28,2513,"0,0111420613",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,96",Deleterious,15,Damaging,"34,02","22,32"
"low bq, low freq, many artifacts, many samples",UPN2_042,21,36206834,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser226Arg/c.678T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),4701,63,4783,"0,0131716496",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,96",Deleterious,15,Damaging,"33,35","17,43"
"low bq, low freq, many artifacts, many samples",UPN2_043,21,36206834,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser226Arg/c.678T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2857,37,2912,"0,012706044",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,96",Deleterious,15,Damaging,"33,49","18,11"
"low bq, low freq, many artifacts, many samples",UPN2_044,21,36206834,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser226Arg/c.678T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),1177,22,1208,"0,0182119205",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,96",Deleterious,15,Damaging,"33,71","20,32"
"low bq, low freq, many artifacts, many samples",UPN2_045,21,36206834,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser226Arg/c.678T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3306,48,3368,"0,0142517815",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,96",Deleterious,15,Damaging,"33,36","15,71"
"low bq, low freq, many artifacts, many samples",UPN2_046,21,36206834,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser226Arg/c.678T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3813,41,3870,"0,0105943152",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,96",Deleterious,15,Damaging,"33,38","18,29"
"low bq, low freq, many artifacts, many samples",UPN2_047,21,36206834,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser226Arg/c.678T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),5624,85,5746,"0,0147928994",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,96",Deleterious,15,Damaging,"33,37","20,64"
"low bq, low freq, many artifacts, many samples",UPN2_048,21,36206834,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser226Arg/c.678T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3998,58,4074,"0,0142366225",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,96",Deleterious,15,Damaging,"33,66","17,78"
"low bq, low freq, many artifacts, many samples",UPN2_049,21,36206834,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser226Arg/c.678T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3837,65,3921,"0,0165774037",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,96",Deleterious,15,Damaging,"33,37","22,86"
"low bq, low freq, many artifacts, many samples",UPN2_050,21,36206834,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser226Arg/c.678T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3789,58,3863,"0,0150142376",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,96",Deleterious,15,Damaging,"33,23","17,69"
"low bq, low freq, many artifacts, many samples",UPN2_051,21,36206834,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser226Arg/c.678T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3814,62,3895,"0,0159178434",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,96",Deleterious,15,Damaging,"33,47","19,15"
"low bq, low freq, many artifacts, many samples",UPN2_052,21,36206834,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser226Arg/c.678T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3099,37,3145,"0,0117647059",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,96",Deleterious,15,Damaging,"33,4","16,86"
"low bq, low freq, many artifacts, many samples",UPN2_053,21,36206834,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser226Arg/c.678T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),4820,72,4918,"0,0146400976",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,96",Deleterious,15,Damaging,"33,4","17,15"
"low bq, low freq, many artifacts, many samples",UPN2_054,21,36206834,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser226Arg/c.678T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2682,34,2733,"0,0124405415",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,96",Deleterious,15,Damaging,"33,22","19,38"
"low bq, low freq, many artifacts, many samples",UPN2_008,21,36206834,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser226Arg/c.678T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),4836,50,4903,"0,0101978381",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,96",Deleterious,15,Damaging,"34,04","16,56"
"low bq, low freq, many artifacts, many samples",UPN2_011,21,36206834,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser226Arg/c.678T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2413,30,2449,"0,0122498979",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,96",Deleterious,15,Damaging,"34,13","19,73"
"low bq, low freq, many artifacts, many samples",UPN2_055,21,36206834,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser226Arg/c.678T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),4638,83,4744,"0,0174957841",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,96",Deleterious,15,Damaging,"33,52","19,54"
"low bq, low freq, many artifacts, many samples",UPN2_056,21,36206834,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser226Arg/c.678T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),1746,21,1772,"0,0118510158",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,96",Deleterious,15,Damaging,"33,24","19,57"
"low bq, low freq, many artifacts",UPN2_058,21,36206834,A,T,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser226Arg/c.678T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2667,34,2715,"0,0125230203",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,96",Deleterious,15,Damaging,"33,52","16,59"
"low bq, low freq, many artifacts",UPN2_081,21,36206844,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu223Ala/c.668A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3857,44,3916,"0,0112359551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,44",Deleterious,27,Damaging,"28,03","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_042,21,36206849,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe221Leu/c.663T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),4717,50,4787,"0,0104449551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,4,Damaging,"34,09",17
"low bq, low freq, many artifacts, many samples",UPN2_053,21,36206849,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe221Leu/c.663T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),4831,63,4917,"0,0128126907",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,4,Damaging,"34,26","17,94"
"low bq, low freq, many artifacts, many samples",UPN2_043,21,36206850,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe221Tyr/c.662T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2870,43,2926,"0,0146958305",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,42,Damaging,"33,99","16,42"
"low bq, low freq, many artifacts, many samples",UPN2_045,21,36206850,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe221Tyr/c.662T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3338,51,3416,"0,0149297424",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,42,Damaging,"33,75","18,02"
"low bq, low freq, many artifacts, many samples",UPN2_046,21,36206850,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe221Tyr/c.662T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3882,41,3947,"0,0103876362",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,42,Damaging,"33,82","16,05"
"low bq, low freq, many artifacts, many samples",UPN2_047,21,36206850,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe221Tyr/c.662T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),5663,67,5782,"0,0115876859",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,42,Damaging,"33,7","15,64"
"low bq, low freq, many artifacts, many samples",UPN2_048,21,36206850,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe221Tyr/c.662T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),4012,56,4089,"0,01369528",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,42,Damaging,"33,92","17,98"
"low bq, low freq, many artifacts, many samples",UPN2_035,21,36206850,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe221Tyr/c.662T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3012,36,3069,"0,0117302053",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,42,Damaging,"34,52","16,44"
"low bq, low freq, many artifacts, many samples",UPN2_049,21,36206850,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe221Tyr/c.662T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3881,42,3956,"0,0106167846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,42,Damaging,"33,88","16,86"
"low bq, low freq, many artifacts, many samples",UPN2_052,21,36206850,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe221Tyr/c.662T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3127,34,3176,"0,0107052897",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,42,Damaging,"33,95","15,71"
"low bq, low freq, many artifacts, many samples",UPN2_053,21,36206850,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe221Tyr/c.662T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),4873,56,4963,"0,0112834979",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,42,Damaging,"33,75","18,68"
"low bq, low freq, many artifacts, many samples",UPN2_055,21,36206850,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe221Tyr/c.662T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),4703,64,4792,"0,0133555927",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,42,Damaging,"33,57","17,38"
"low bq, low freq, many artifacts, many samples",UPN2_057,21,36206850,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe221Tyr/c.662T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),3092,37,3141,"0,011779688",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,42,Damaging,"33,9","18,65"
"low bq, low freq, many artifacts",UPN2_058,21,36206850,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe221Tyr/c.662T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|7|T),2716,33,2761,"0,0119521912",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,26",Neutral,42,Damaging,"33,94","15,97"
"many artifacts, strandbias, many samples",UPN2_001,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4780,978,5779,"0,1692334314",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,23","31,13"
"many artifacts, strandbias, many samples",UPN2_014,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),8932,1097,10060,"0,1090457256",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,37","31,11"
"many artifacts, strandbias, many samples",UPN2_015,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),12844,1228,14119,"0,0869749982",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,46","31,54"
"many artifacts, strandbias, many samples",UPN2_016,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6119,686,6824,"0,1005275498",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,38","31,75"
"many artifacts, strandbias, many samples",UPN2_017,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4191,528,4734,"0,1115335868",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,45","31,32"
"many artifacts, strandbias, many samples",UPN2_018,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6950,855,7822,"0,1093070826",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,47","31,3"
"many artifacts, strandbias, many samples",UPN2_019,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),7267,899,8194,"0,1097144252",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,43","31,45"
"many artifacts, strandbias, many samples",UPN2_020,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6019,731,6768,"0,1080082742",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,38","31,44"
"many artifacts, strandbias, many samples",UPN2_021,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6369,859,7244,"0,1185808945",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,4","31,36"
"many artifacts, strandbias, many samples",UPN2_002,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6456,1340,7822,"0,171311685",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,26","31,11"
"many artifacts, strandbias, many samples",UPN2_003,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1205,247,1456,"0,1696428571",1,1,0,0,1,1,0,0,4,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,27","31,36"
"many artifacts, strandbias, many samples",UPN2_022,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),9742,1337,11119,"0,1202446263",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,34","31,4"
"many artifacts, strandbias, many samples",UPN2_023,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),11362,1450,12866,"0,1127001399",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,34","31,31"
"many artifacts, strandbias, many samples",UPN2_041,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),18282,994,19340,"0,0513960703",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,19","31,21"
"many artifacts, strandbias, many samples",UPN2_024,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4898,471,5387,"0,0874327084",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,37","31,58"
"many artifacts, strandbias, many samples",UPN2_025,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),11731,1550,13346,"0,1161396673",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,31","31,2"
"many artifacts, strandbias, many samples",UPN2_026,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),11915,1399,13354,"0,1047626179",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,41","31,43"
"many artifacts, strandbias, many samples",UPN2_004,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1161,234,1399,"0,1672623302",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,16","31,27"
"many artifacts, strandbias, many samples",UPN2_027,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),12059,1578,13671,"0,1154268159",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,32","31,38"
"many artifacts, strandbias, many samples",UPN2_089,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),8851,421,9290,"0,0453175457",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,46","31,71"
"many artifacts, strandbias, many samples",UPN2_042,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),19133,1113,20330,"0,0547466798",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,23","31,16"
"many artifacts, strandbias, many samples",UPN2_028,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),9100,1184,10318,"0,1147509207",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,3","31,34"
"many artifacts, strandbias, many samples",UPN2_043,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),10887,651,11598,"0,0561303673",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,25","31,1"
"many artifacts, strandbias, many samples",UPN2_044,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3920,251,4186,"0,0599617774",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,43","31,05"
"many artifacts, strandbias, many samples",UPN2_029,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),10332,1288,11658,"0,1104820724",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,23","31,41"
"many artifacts, strandbias, many samples",UPN2_030,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),10234,1279,11548,"0,1107551091",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,42","31,4"
"many artifacts, strandbias, many samples",UPN2_031,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),7177,792,7994,"0,0990743057",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,44","31,48"
"many artifacts, strandbias, many samples",UPN2_005,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),1908,397,2315,"0,1714902808",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,45","31,19"
"many artifacts, strandbias, many samples",UPN2_045,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),14577,698,15339,"0,0455049221",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,2","31,3"
"many artifacts, strandbias, many samples",UPN2_032,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4060,450,4528,"0,0993816254",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,22","31,44"
"many artifacts, strandbias, many samples",UPN2_046,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),15433,1225,16720,"0,0732655502",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,27","31,14"
"many artifacts, strandbias, many samples",UPN2_033,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),8006,927,8974,"0,1032984177",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,4","31,34"
"many artifacts, strandbias, many samples",UPN2_034,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),2909,302,3222,"0,0937306021",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,3","31,37"
"many artifacts, strandbias, many samples",UPN2_047,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),22788,1490,24388,"0,0610956208",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,23","31,17"
"many artifacts, strandbias, many samples",UPN2_048,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),19315,1531,20897,"0,0732641049",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,2","30,97"
"many artifacts, strandbias, many samples",UPN2_035,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),13803,1768,15634,"0,113086862",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,36","31,21"
"many artifacts, strandbias, many samples",UPN2_036,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),14086,1951,16104,"0,1211500248",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,22","31,31"
"many artifacts, strandbias, many samples",UPN2_006,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5050,982,6041,"0,1625558682",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,22","31,31"
"many artifacts, strandbias, many samples",UPN2_049,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),15034,1030,16139,"0,0638205589",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,31","31,23"
"many artifacts, strandbias, many samples",UPN2_050,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),15180,621,15858,"0,0391600454",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,23","31,19"
"many artifacts, strandbias, many samples",UPN2_037,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),16372,1965,18386,"0,106874796",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,45","31,32"
"many artifacts, strandbias, many samples",UPN2_051,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),13558,771,14396,"0,0535565435",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,31","31,4"
"many artifacts, strandbias, many samples",UPN2_052,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),12982,560,13572,"0,0412614206",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,22","31,31"
"many artifacts, strandbias, many samples",UPN2_038,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),17366,2206,19634,"0,1123561169",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,45","31,37"
"many artifacts, strandbias, many samples",UPN2_039,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),18658,2404,21141,"0,113712691",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,41","31,41"
"many artifacts, strandbias, many samples",UPN2_053,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),17596,1242,18924,"0,0656309448",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,28","31,57"
"many artifacts, strandbias, many samples",UPN2_054,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),10888,630,11570,"0,0544511668",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,19","31,11"
"many artifacts, strandbias, many samples",UPN2_007,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),13889,2537,16486,"0,1538881475",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,35","31,1"
"many artifacts, strandbias, many samples",UPN2_008,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),20053,3624,23764,"0,1524995792",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,42","31,22"
"many artifacts, strandbias, many samples",UPN2_009,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),17210,2794,20079,"0,1391503561",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,35","31,25"
"many artifacts, strandbias, many samples",UPN2_010,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),10836,2014,12890,"0,1562451513",1,1,0,0,1,1,0,0,4,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,23","31,39"
"many artifacts, strandbias, many samples",UPN2_011,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),11564,2247,13848,"0,1622616984",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,25","31,2"
"many artifacts, strandbias, many samples",UPN2_055,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),17667,1139,18896,"0,0602773074",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,23","31,08"
"many artifacts, strandbias, many samples",UPN2_056,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),8432,516,8984,"0,0574354408",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,12","31,19"
"many artifacts, strandbias, many samples",UPN2_090,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),7143,263,7414,"0,0354734286",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,25","31,83"
"many artifacts, strandbias, many samples",UPN2_057,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),14487,1131,15702,"0,0720290409",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,15","31,3"
"many artifacts, strandbias, many samples",UPN2_058,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),14315,1395,15768,"0,0884703196",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,1","31,06"
"many artifacts, strandbias, many samples",UPN2_059,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),9499,1455,10984,"0,1324654042",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"31,87","31,25"
"many artifacts, strandbias, many samples",UPN2_012,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6593,1261,7876,"0,1601066531",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,24","31,34"
"many artifacts, strandbias, many samples",UPN2_060,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),8881,1357,10286,"0,1319268909",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,12","31,15"
"many artifacts, strandbias, many samples",UPN2_040,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),19705,2493,22267,"0,1119594018",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,4","31,43"
"inspected, many artifacts, strandbias, many samples",UPN2_013,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),3770,678,4460,"0,1520179372",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,5","31,08"
"many artifacts, strandbias, many samples",UPN2_091,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6392,356,6761,"0,0526549327",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,54","31,54"
"many artifacts, strandbias, many samples",UPN2_092,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4169,143,4318,"0,0331171839",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,36","31,13"
"many artifacts, strandbias, many samples",UPN2_093,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5230,231,5468,"0,0422457937",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,42","30,97"
"inspected, many artifacts, strandbias, many samples",UPN2_061,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),7455,1083,8573,"0,1263268401",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,32","31,34"
"many artifacts, strandbias, many samples",UPN2_062,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),8867,1255,10155,"0,1235844412",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,3","31,29"
"many artifacts, strandbias, many samples",UPN2_063,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),7617,1285,8934,"0,1438325498",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,14","31,37"
"many artifacts, strandbias, many samples",UPN2_064,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),8518,1475,10037,"0,1469562618",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,07","31,3"
"many artifacts, strandbias, many samples",UPN2_065,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6674,1086,7771,"0,1397503539",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"31,68","31,2"
"many artifacts, strandbias, many samples",UPN2_066,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),8821,1450,10309,"0,1406537977",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"31,74","31,16"
"many artifacts, strandbias, many samples",UPN2_067,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),8502,1482,10023,"0,1478599222",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"31,84","31,05"
"many artifacts, strandbias, many samples",UPN2_068,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6742,1012,7780,"0,1300771208",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"31,92","31,21"
"many artifacts, strandbias, many samples",UPN2_069,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),8314,1273,9620,"0,1323284823",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,07","31,24"
"many artifacts, strandbias, many samples",UPN2_070,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6199,976,7189,"0,1357629712",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,01","31,24"
"many artifacts, strandbias, many samples",UPN2_071,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),7035,948,8004,"0,1184407796",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,54",31
"many artifacts, strandbias, many samples",UPN2_072,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),8622,1096,9751,"0,1123987283",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,45","31,2"
"many artifacts, strandbias, many samples",UPN2_073,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6167,879,7074,"0,1242578456",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,24","31,19"
"many artifacts, strandbias, many samples",UPN2_074,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),5040,868,5930,"0,1463743676",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"31,95","31,14"
"many artifacts, strandbias, many samples",UPN2_075,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),9882,1422,11338,"0,1254189451",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,2","31,04"
"many artifacts, strandbias, many samples",UPN2_076,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),7597,1168,8792,"0,1328480437",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,12","31,26"
"many artifacts, strandbias, many samples",UPN2_077,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),7064,1122,8206,"0,1367292225",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,16","31,15"
"many artifacts, strandbias, many samples",UPN2_078,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),8403,1323,9764,"0,1354977468",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,22","31,25"
"many artifacts, strandbias, many samples",UPN2_079,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4949,821,5789,"0,1418206944",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,19","31,4"
"many artifacts, strandbias, many samples",UPN2_080,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),10137,1455,11620,"0,1252151463",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,47","31,19"
"many artifacts, strandbias, many samples",UPN2_081,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),12994,1575,14606,"0,1078323976",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,41","31,38"
"many artifacts, strandbias, many samples",UPN2_082,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),9270,1382,10683,"0,1293644107",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"31,93","31,08"
"many artifacts, strandbias, many samples",UPN2_083,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),8733,1350,10104,"0,1336104513",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,1","31,27"
"many artifacts, strandbias, many samples",UPN2_084,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),9958,1434,11415,"0,1256241787",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,04","31,15"
"inspected, many artifacts, strandbias, many samples",UPN2_085,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),9313,1462,10817,"0,1351576223",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"31,95","31,07"
"many artifacts, strandbias, many samples",UPN2_086,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),6712,1042,7787,"0,1338127649",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"31,84","31,14"
"many artifacts, strandbias, many samples",UPN2_087,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),8650,1359,10030,"0,1354935194",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,07","31,21"
"many artifacts, strandbias, many samples",UPN2_088,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),7313,1231,8577,"0,1435233765",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"31,99","31,15"
"many artifacts, strandbias, many samples",UPN2_094,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),8768,357,9140,"0,039059081",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,53","31,69"
"many artifacts, strandbias, many samples",UPN2_095,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),8201,397,8623,"0,0460396614",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,57","31,69"
"many artifacts, strandbias, many samples",UPN2_096,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),8345,356,8724,"0,0408069693",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,48","31,92"
"many artifacts, strandbias, many samples",UPN2_097,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),9607,489,10116,"0,0483392645",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,59","31,55"
"inspected, many artifacts, strandbias, many samples",UPN2_098,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),8306,389,8711,"0,0446561818",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,41","31,46"
"many artifacts, strandbias, many samples",UPN2_099,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4409,174,4594,"0,0378754898",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,5","31,82"
"many artifacts, strandbias, many samples",UPN2_100,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),8119,275,8408,"0,0327069458",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,6","31,73"
"many artifacts, strandbias, many samples",UPN2_101,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),7979,289,8279,"0,0349075975",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,53","31,72"
"many artifacts, strandbias, many samples",UPN2_102,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),8782,358,9151,"0,0391214075",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,4","31,42"
"many artifacts, strandbias, many samples",UPN2_103,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),8341,360,8718,"0,0412938747",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,59","31,16"
"many artifacts, strandbias, many samples",UPN2_104,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),9588,477,10083,"0,047307349",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,52","31,36"
"many artifacts, strandbias, many samples",UPN2_105,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),8842,364,9233,"0,0394238059",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,57","31,31"
"many artifacts, strandbias, many samples",UPN2_106,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),12771,455,13258,"0,0343189018",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,54","31,54"
"many artifacts, strandbias, many samples",UPN2_107,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),13964,623,14616,"0,0426245211",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,48","31,48"
"many artifacts, strandbias, many samples",UPN2_108,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),12730,416,13166,"0,0315965365",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,63","31,53"
"many artifacts, strandbias, many samples",UPN2_109,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),12025,383,12443,"0,0307803584",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,53","31,64"
"many artifacts, strandbias, many samples",UPN2_110,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),13582,375,13984,"0,0268163616",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,56","31,79"
"many artifacts, strandbias, many samples",UPN2_111,21,36206851,A,G,missense_variant(MODERATE|MISSENSE|Ttt/Ctt|p.Phe221Leu/c.661T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),11253,509,11777,"0,0432198353",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,58",Deleterious,"0,004",Damaging,"32,43","31,55"
"low freq, many artifacts",UPN2_044,21,36206867,CT,C,frameshift_variant(HIGH||aag/|p.Lys215fs/c.644delA|480|RUNX1|protein_coding|CODING|ENST00000437180|7|C),4113,49,4210,"0,0116389549",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,94",NA
"low freq, many artifacts",UPN2_044,21,36206884,GT,G,frameshift_variant(HIGH||aaa/|p.Lys209fs/c.627delA|480|RUNX1|protein_coding|CODING|ENST00000437180|7|G),4121,48,4210,"0,0114014252",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,43",NA
"low freq, many artifacts",UPN2_083,21,36231774,G,A,stop_gained(HIGH|NONSENSE|Cga/Tga|p.Arg204*/c.610C>T|480|RUNX1|protein_coding|CODING|ENST00000437180|6|A),12310,177,12495,"0,0141656663",0,0,0,0,1,0,0,1,2,NO,NO,COSM25124,haematopoietic_and_lymphoid_tissue,6,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,22","35,02"
"low freq, many artifacts",UPN2_044,21,36231776,G,T,missense_variant(MODERATE|MISSENSE|cCt/cAt|p.Pro203His/c.608C>A|480|RUNX1|protein_coding|CODING|ENST00000437180|6|T),3219,35,3255,"0,0107526882",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,49",Deleterious,"0,01",Damaging,"35,25","35,14"
"low bq, bad alignment, many samples",UPN2_059,21,36231827,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val186Gly/c.557T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),9565,302,9934,"0,0304006443",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"26,14","14,68"
"low bq, bad alignment, many samples",UPN2_060,21,36231827,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val186Gly/c.557T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),9592,286,9908,"0,0288655632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"26,49","15,16"
"low bq, bad alignment, many samples",UPN2_061,21,36231827,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val186Gly/c.557T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),9169,298,9506,"0,0313486219",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"25,72","15,04"
"low bq, bad alignment, many samples",UPN2_062,21,36231827,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val186Gly/c.557T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),8239,314,8598,"0,036520121",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"25,29","14,8"
"low bq, bad alignment, many samples",UPN2_063,21,36231827,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val186Gly/c.557T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),8472,260,8770,"0,0296465222",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"26,18","14,75"
"low bq, bad alignment, many samples",UPN2_064,21,36231827,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val186Gly/c.557T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),9108,288,9454,"0,030463296",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"25,78","14,73"
"low bq, bad alignment, many samples",UPN2_065,21,36231827,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val186Gly/c.557T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),7356,226,7622,"0,0296510102",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"26,11","14,94"
"low bq, bad alignment, many samples",UPN2_066,21,36231827,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val186Gly/c.557T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),8859,287,9175,"0,031280654",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"26,52","15,21"
"low bq, bad alignment, many samples",UPN2_067,21,36231827,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val186Gly/c.557T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),11183,290,11516,"0,025182355",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"26,76",15
"low bq, bad alignment, many samples",UPN2_068,21,36231827,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val186Gly/c.557T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),9328,347,9718,"0,0357069356",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"25,37","14,82"
"low bq, bad alignment, many samples",UPN2_069,21,36231827,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val186Gly/c.557T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),10604,337,10990,"0,0306642402",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"25,68","15,23"
"low bq, bad alignment, many samples",UPN2_070,21,36231827,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val186Gly/c.557T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),6474,210,6726,"0,0312221231",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"25,4","14,96"
"low bq, bad alignment, many samples",UPN2_071,21,36231827,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val186Gly/c.557T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),7606,270,7910,"0,0341340076",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"26,02","14,79"
"low bq, bad alignment, many samples",UPN2_072,21,36231827,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val186Gly/c.557T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),8933,302,9272,"0,0325711821",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"25,96","15,01"
"low bq, bad alignment, many samples",UPN2_073,21,36231827,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val186Gly/c.557T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),8307,250,8597,"0,0290799116",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"26,28","15,15"
"low bq, bad alignment, many samples",UPN2_074,21,36231827,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val186Gly/c.557T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),6691,206,6922,"0,0297601849",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"26,31","15,18"
"low bq, bad alignment, many samples",UPN2_075,21,36231827,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val186Gly/c.557T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),10985,317,11359,"0,0279073862",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"26,73","14,79"
"low bq, bad alignment, many samples",UPN2_076,21,36231827,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val186Gly/c.557T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),8478,316,8846,"0,0357223604",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"25,54","14,83"
"low bq, bad alignment, many samples",UPN2_077,21,36231827,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val186Gly/c.557T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),10477,353,10877,"0,0324538016",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"25,84","14,94"
"low bq, bad alignment, many samples",UPN2_078,21,36231827,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val186Gly/c.557T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),9259,318,9619,"0,0330595696",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"25,58","15,35"
"low bq, bad alignment, many samples",UPN2_079,21,36231827,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val186Gly/c.557T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),6202,194,6415,"0,0302416212",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"25,74","14,75"
"low bq, bad alignment, many samples",UPN2_080,21,36231827,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val186Gly/c.557T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),11297,362,11709,"0,0309163891",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"26,1","14,58"
"low bq, bad alignment, many samples",UPN2_081,21,36231827,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val186Gly/c.557T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),14082,438,14596,"0,0300082214",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"26,27","15,03"
"low bq, bad alignment, many samples",UPN2_082,21,36231827,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val186Gly/c.557T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),10781,332,11177,"0,0297038561",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"26,45","15,18"
"low bq, bad alignment, many samples",UPN2_083,21,36231827,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val186Gly/c.557T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),12019,410,12484,"0,0328420378",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"25,56","14,88"
"low bq, bad alignment, many samples",UPN2_084,21,36231827,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val186Gly/c.557T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),10140,381,10563,"0,0360692985",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"25,42","14,72"
"low bq, bad alignment, many samples",UPN2_085,21,36231827,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val186Gly/c.557T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),8758,309,9105,"0,033937397",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"25,88","15,11"
"low bq, bad alignment, many samples",UPN2_086,21,36231827,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val186Gly/c.557T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),5796,205,6030,"0,0339966833",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"25,27","15,08"
"low bq, bad alignment, many samples",UPN2_087,21,36231827,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val186Gly/c.557T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),11712,358,12116,"0,0295477055",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"25,95",15
"low bq, bad alignment",UPN2_088,21,36231827,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val186Gly/c.557T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),8042,227,8301,"0,0273461029",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"26,85","15,56"
"low freq, many artifacts",UPN2_044,21,36231827,A,T,missense_variant(MODERATE|MISSENSE|gTc/gAc|p.Val186Asp/c.557T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|6|T),3186,35,3252,"0,0107626076",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,43",Deleterious,0,Damaging,"26,83","32,06"
"low bq, low freq, many artifacts",UPN2_077,21,36231829,T,G,missense_variant(MODERATE|MISSENSE|caA/caC|p.Gln185His/c.555A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),10721,117,10877,"0,0107566425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,76",Deleterious,9,Damaging,"30,86","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_059,21,36231839,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn182Thr/c.545A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),9699,182,9932,"0,0183246073",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,133,Tolerated,"28,56","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_060,21,36231839,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn182Thr/c.545A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),9654,200,9908,"0,0201857085",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,133,Tolerated,"28,84","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_061,21,36231839,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn182Thr/c.545A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),9246,207,9503,"0,021782595",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,133,Tolerated,"28,19","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_062,21,36231839,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn182Thr/c.545A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),8355,182,8595,"0,0211751018",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,133,Tolerated,"28,09","15,55"
"low bq, low freq, many artifacts, many samples",UPN2_063,21,36231839,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn182Thr/c.545A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),8552,176,8770,"0,0200684151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,133,Tolerated,"28,55","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_064,21,36231839,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn182Thr/c.545A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),9210,186,9451,"0,0196804571",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,133,Tolerated,"28,31","16,01"
"low bq, low freq, many artifacts, many samples",UPN2_065,21,36231839,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn182Thr/c.545A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),7445,134,7620,"0,0175853018",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,133,Tolerated,"28,52","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_066,21,36231839,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn182Thr/c.545A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),8927,183,9172,"0,0199520279",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,133,Tolerated,"28,72","15,41"
"low bq, low freq, many artifacts, many samples",UPN2_067,21,36231839,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn182Thr/c.545A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),11265,190,11512,"0,016504517",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,133,Tolerated,"28,88","15,65"
"low bq, many samples",UPN2_068,21,36231839,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn182Thr/c.545A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),9433,225,9716,"0,0231576781",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,133,Tolerated,"28,02","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_069,21,36231839,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn182Thr/c.545A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),10700,235,10989,"0,0213850214",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,133,Tolerated,"28,32","15,31"
"low bq, low freq, many artifacts, many samples",UPN2_070,21,36231839,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn182Thr/c.545A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),6554,140,6723,"0,0208240369",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,133,Tolerated,"27,96","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_071,21,36231839,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn182Thr/c.545A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),7709,156,7909,"0,0197243646",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,133,Tolerated,"28,47","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_072,21,36231839,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn182Thr/c.545A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),9043,184,9274,"0,0198404141",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,133,Tolerated,"28,16","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_073,21,36231839,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn182Thr/c.545A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),8372,177,8597,"0,0205885774",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,133,Tolerated,"28,6","15,64"
"low bq, low freq, many artifacts, many samples",UPN2_074,21,36231839,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn182Thr/c.545A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),6779,105,6919,"0,0151756034",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,133,Tolerated,"28,69","15,68"
"low bq, low freq, many artifacts, many samples",UPN2_075,21,36231839,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn182Thr/c.545A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),11118,187,11358,"0,0164641662",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,133,Tolerated,"28,91","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_076,21,36231839,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn182Thr/c.545A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),8628,184,8845,"0,0208027134",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,133,Tolerated,"28,05","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_077,21,36231839,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn182Thr/c.545A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),10608,209,10878,"0,0192130906",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,133,Tolerated,"28,22","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_078,21,36231839,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn182Thr/c.545A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),9364,209,9615,"0,0217368695",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,133,Tolerated,"28,26","15,56"
"low bq, low freq, many artifacts, many samples",UPN2_079,21,36231839,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn182Thr/c.545A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),6255,127,6415,"0,01979735",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,133,Tolerated,"28,48","15,8"
"low bq, low freq, many artifacts, many samples",UPN2_080,21,36231839,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn182Thr/c.545A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),11414,225,11707,"0,0192192705",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,133,Tolerated,"28,47","15,25"
"low bq, low freq, many artifacts, many samples",UPN2_081,21,36231839,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn182Thr/c.545A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),14222,290,14592,"0,0198739035",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,133,Tolerated,"28,54","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_082,21,36231839,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn182Thr/c.545A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),10931,185,11174,"0,0165562914",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,133,Tolerated,"28,61","15,54"
"low bq, low freq, many artifacts, many samples",UPN2_083,21,36231839,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn182Thr/c.545A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),12173,249,12479,"0,0199535219",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,133,Tolerated,"28,08","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_084,21,36231839,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn182Thr/c.545A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),10293,222,10562,"0,0210187464",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,133,Tolerated,"28,13","15,43"
"low bq, low freq, many artifacts, many samples",UPN2_085,21,36231839,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn182Thr/c.545A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),8864,195,9105,"0,021416804",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,133,Tolerated,"28,26","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_086,21,36231839,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn182Thr/c.545A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),5868,128,6030,"0,0212271973",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,133,Tolerated,"28,05","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_087,21,36231839,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn182Thr/c.545A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),11781,258,12116,"0,0212941565",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,133,Tolerated,"28,41","14,72"
"low bq, low freq, many artifacts",UPN2_088,21,36231839,T,G,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn182Thr/c.545A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),8113,149,8299,"0,0179539704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,32",Deleterious,133,Tolerated,"29,12","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_064,21,36231840,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn182His/c.544A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),9314,95,9451,"0,0100518464",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,49",Deleterious,7,Damaging,"30,79","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_069,21,36231840,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn182His/c.544A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),10834,110,10994,"0,0100054575",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,49",Deleterious,7,Damaging,"30,69","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_072,21,36231840,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn182His/c.544A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),9138,102,9273,"0,0109996765",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,49",Deleterious,7,Damaging,"30,78","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_077,21,36231840,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn182His/c.544A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),10706,116,10876,"0,0106656859",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,49",Deleterious,7,Damaging,"30,71","15,34"
"low bq, low freq, many artifacts",UPN2_087,21,36231840,T,G,missense_variant(MODERATE|MISSENSE|Aac/Cac|p.Asn182His/c.544A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),11930,131,12115,"0,0108130417",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,49",Deleterious,7,Damaging,"30,62","15,08"
"low bq, bad alignment, many samples",UPN2_001,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),10310,357,10713,"0,0333239989",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,29","16,01"
"strandbias, many samples, low bq",UPN2_014,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),15574,1101,16783,"0,0656020974",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,03","15,39"
"strandbias, many samples, low bq",UPN2_015,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),22103,1783,24022,"0,0742236283",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"25,99","15,34"
"low bq, many samples",UPN2_016,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),8984,437,9467,"0,0461603465",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"28,52","15,32"
"strandbias, many samples, low bq",UPN2_017,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),6849,519,7403,"0,0701067135",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"25,92","15,65"
"strandbias, many samples, low bq",UPN2_018,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),11948,898,12910,"0,0695584818",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,09","15,55"
"low bq, bad alignment, many samples",UPN2_019,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),13161,992,14255,"0,0695896177",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"25,94","15,34"
"strandbias, many samples, low bq",UPN2_020,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),9631,695,10392,"0,066878368",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,13","15,38"
"strandbias, many samples, low bq",UPN2_021,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),12408,875,13345,"0,0655676283",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,02","15,34"
"low bq, bad alignment, many samples",UPN2_002,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),13256,501,13846,"0,0361837354",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,12","15,89"
"low bq, bad alignment, many samples",UPN2_003,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),2559,95,2670,"0,0355805243",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,06","15,43"
"strandbias, many samples, low bq",UPN2_022,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),16806,1293,18166,"0,0711769239",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,26,"15,57"
"strandbias, many samples, low bq",UPN2_023,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),17754,1403,19268,"0,0728150301",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,15","15,3"
"strandbias, many samples, low bq",UPN2_041,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),20345,1031,21514,"0,0479222832",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,51","15,74"
"strandbias, many samples, low bq",UPN2_024,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),7416,556,8020,"0,0693266833",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,16","15,88"
"strandbias, many samples, low bq",UPN2_025,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),20628,1520,22276,"0,0682348716",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,23","15,58"
"strandbias, many samples, low bq",UPN2_026,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),18869,1503,20491,"0,0733492753",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"25,96","15,48"
"low bq, bad alignment, many samples",UPN2_004,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),4199,185,4409,"0,041959628",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,22","15,49"
"strandbias, many samples, low bq",UPN2_027,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),21268,1694,23103,"0,0733238108",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,09","15,42"
"strandbias, many samples, low bq",UPN2_089,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),13280,704,14040,"0,0501424501",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"27,63","17,38"
"low bq, bad alignment, many samples",UPN2_042,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),29566,1466,31243,"0,0469225106",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,53","15,49"
"low bq, bad alignment, many samples",UPN2_028,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),15704,1337,17133,"0,0780365377",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,02","15,2"
"low bq, bad alignment, many samples",UPN2_043,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),18813,818,19756,"0,0414051427",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,55","15,37"
"low bq, bad alignment, many samples",UPN2_044,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),6002,294,6374,"0,0461248823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,33","16,01"
"strandbias, many samples, low bq",UPN2_029,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),17321,1364,18779,"0,0726343256",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,12","15,61"
"strandbias, many samples, low bq",UPN2_030,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),17866,1392,19391,"0,07178588",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,06","15,42"
"strandbias, many samples, low bq",UPN2_031,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),11638,878,12596,"0,0697046681",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,05","15,55"
"low bq, bad alignment, many samples",UPN2_005,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),3936,144,4100,"0,0351219512",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"25,96","15,45"
"strandbias, many samples, low bq",UPN2_045,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),20265,1060,21466,"0,0493804155",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,49","15,74"
"low bq, bad alignment, many samples",UPN2_032,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),6807,504,7337,"0,0686929263",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,04","15,55"
"low bq, bad alignment, many samples",UPN2_046,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),25991,1313,27438,"0,0478533421",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,38","15,63"
"strandbias, many samples, low bq",UPN2_033,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),13751,963,14813,"0,0650104638",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,13","15,39"
"low bq, bad alignment, many samples",UPN2_034,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),5101,344,5480,"0,0627737226",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,09","15,04"
"low bq, bad alignment, many samples",UPN2_047,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),35008,1797,37080,"0,0484627832",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,52","15,48"
"strandbias, many samples, low bq",UPN2_048,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),32206,1633,34120,"0,0478604924",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,42","15,82"
"strandbias, many samples, low bq",UPN2_035,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),16247,1216,17544,"0,0693114455",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,08","15,26"
"strandbias, many samples, low bq",UPN2_036,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),17089,1265,18446,"0,0685785536",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,15","15,39"
"low bq, bad alignment, many samples",UPN2_006,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),11751,459,12271,"0,0374052644",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,2","15,35"
"low bq, bad alignment, many samples",UPN2_049,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),23220,1152,24530,"0,0469629026",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,5","15,51"
"low bq, bad alignment, many samples",UPN2_050,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),21975,1081,23215,"0,0465647211",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,55","15,57"
"strandbias, many samples, low bq",UPN2_037,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),26023,1940,28159,"0,068894492",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"25,96","15,43"
"low bq, bad alignment, many samples",UPN2_051,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),22003,961,23095,"0,0416107383",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,54","15,37"
"low bq, bad alignment, many samples",UPN2_052,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),19679,1001,20823,"0,0480718436",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,51","15,48"
"strandbias, many samples, low bq",UPN2_038,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),31122,2381,33698,"0,0706570123",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,03","15,47"
"strandbias, many samples, low bq",UPN2_039,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),16677,1343,18111,"0,0741538292",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"25,99","15,62"
"low bq, bad alignment, many samples",UPN2_053,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),27262,1331,28769,"0,046265077",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,46","15,46"
"low bq, bad alignment, many samples",UPN2_054,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),18715,968,19785,"0,048925954",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,41","15,42"
"low bq, bad alignment, many samples",UPN2_007,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),28537,1013,29696,"0,0341123384",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,43","15,6"
"low bq, bad alignment, many samples",UPN2_008,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),38282,1543,40035,"0,0385412764",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,07","15,71"
"low bq, bad alignment, many samples",UPN2_009,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),29893,1192,31257,"0,0381354577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,13","15,51"
"low bq, bad alignment, many samples",UPN2_010,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),24472,1039,25654,"0,0405005067",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,12","15,79"
"low bq, bad alignment, many samples",UPN2_011,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),24654,962,25713,"0,0374129818",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,17","15,23"
"low bq, bad alignment, many samples",UPN2_055,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),26582,1350,28090,"0,0480598078",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,44","15,59"
"low bq, bad alignment, many samples",UPN2_056,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),13365,686,14125,"0,0485663717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,42","15,5"
"low bq, many samples",UPN2_090,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),10454,524,11022,"0,0475412811",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"27,54","17,18"
"low bq, bad alignment, many samples",UPN2_057,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),24934,1282,26360,"0,0486342944",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,48","15,67"
"low bq, bad alignment, many samples",UPN2_058,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),22957,1032,24120,"0,0427860697",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,64","15,65"
"strandbias, many samples, low bq",UPN2_059,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),17563,1792,19430,"0,0922285126",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,49","18,75"
"low bq, bad alignment, many samples",UPN2_012,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),12438,480,13004,"0,0369117195",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,17","15,59"
"strandbias, many samples, low bq",UPN2_060,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),17365,1894,19360,"0,0978305785",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,55","18,88"
"strandbias, many samples, low bq",UPN2_040,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),12394,912,13373,"0,0681971136",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,09","15,39"
"low bq, bad alignment, many samples",UPN2_013,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),8013,288,8344,"0,0345158198",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,31","15,77"
"low bq, many samples",UPN2_091,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),11354,596,11996,"0,0496832277",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"27,6","16,86"
"strandbias, many samples, low bq",UPN2_092,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),6137,318,6471,"0,0491423273",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"27,48","16,97"
"strandbias, many samples, low bq",UPN2_093,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),8696,381,9113,"0,0418084056",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"27,66","16,58"
"strandbias, many samples, low bq",UPN2_061,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),16550,1848,18491,"0,0999405116",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,5","18,89"
"strandbias, many samples, low bq",UPN2_062,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),15026,1739,16822,"0,1033765307",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,37","18,87"
"strandbias, many samples, low bq",UPN2_063,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),15446,1615,17156,"0,0941361623",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,52","19,11"
"strandbias, many samples, low bq",UPN2_064,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),16687,1741,18499,"0,0941131953",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,33","18,91"
"strandbias, many samples, low bq",UPN2_065,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),13329,1448,14839,"0,0975806995",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,54","19,06"
"strandbias, many samples, low bq",UPN2_066,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),16083,1749,17898,"0,0977204157",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,6","19,04"
"strandbias, many samples, low bq",UPN2_067,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),20494,1915,22514,"0,085058186",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,58","18,66"
"strandbias, many samples, low bq",UPN2_068,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),17008,1882,18977,"0,0991726827",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,39","18,76"
"strandbias, many samples, low bq",UPN2_069,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),19207,2127,21435,"0,0992302309",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,56","18,86"
"strandbias, many samples, low bq",UPN2_070,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),11754,1299,13120,"0,0990091463",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,37","18,74"
"strandbias, many samples, low bq",UPN2_071,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),13970,1431,15465,"0,0925315228",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,46","18,72"
"strandbias, many samples, low bq",UPN2_072,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),16295,1759,18137,"0,0969840657",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,42","18,88"
"strandbias, many samples, low bq",UPN2_073,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),15055,1674,16808,"0,0995954307",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,55","18,83"
"strandbias, many samples, low bq",UPN2_074,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),12149,1339,13533,"0,0989433237",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,56","18,94"
"strandbias, many samples, low bq",UPN2_075,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),20168,2015,22267,"0,0904926573",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,61","18,31"
"strandbias, many samples, low bq",UPN2_076,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),15429,1743,17251,"0,101037621",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,47","18,83"
"strandbias, many samples, low bq",UPN2_077,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),18957,2175,21255,"0,1023288638",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,48","19,09"
"strandbias, many samples, low bq",UPN2_078,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),16720,1997,18822,"0,1060992456",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,5","18,68"
"inspected, strandbias, many samples",UPN2_079,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),11198,1293,12556,"0,1029786556",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,45","19,13"
"strandbias, many samples, low bq",UPN2_080,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),20691,2086,22883,"0,091159376",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,39","18,79"
"strandbias, many samples, low bq",UPN2_081,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),25694,2665,28505,"0,0934923698",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,58","18,85"
"strandbias, many samples, low bq",UPN2_082,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),19622,2064,21790,"0,0947223497",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,54","18,7"
"strandbias, many samples, low bq",UPN2_083,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),21931,2309,24350,"0,094825462",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,38","19,11"
"strandbias, many samples, low bq",UPN2_084,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),18635,1937,20660,"0,0937560503",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,34","18,65"
"strandbias, many samples, low bq",UPN2_085,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),16031,1727,17850,"0,0967507003",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,47","18,76"
"strandbias, many samples, low bq",UPN2_086,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),10550,1144,11765,"0,0972375691",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,5","19,07"
"strandbias, many samples, low bq",UPN2_087,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),21324,2254,23689,"0,0951496475",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,44","18,9"
"low bq, bad alignment, many samples",UPN2_088,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),14750,1379,16213,"0,0850552026",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"26,58","18,54"
"low bq, many samples",UPN2_094,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),13742,724,14522,"0,0498553918",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"27,64","17,29"
"strandbias, many samples, low bq",UPN2_095,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),12965,733,13739,"0,0533517723",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"27,55","17,65"
"strandbias, many samples, low bq",UPN2_096,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),13567,691,14338,"0,0481936114",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"27,55","17,18"
"strandbias, many samples, low bq",UPN2_097,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),14530,764,15352,"0,0497655029",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"27,54","17,18"
"strandbias, many samples, low bq",UPN2_098,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),14234,742,15021,"0,0493975102",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"27,56","16,95"
"strandbias, many samples, low bq",UPN2_099,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),7062,352,7436,"0,0473372781",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"27,53","17,2"
low bq,UPN2_100,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),12666,569,13298,"0,0427883892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"27,56","16,56"
"strandbias, many samples, low bq",UPN2_101,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),12385,620,13052,"0,0475022985",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"27,65","17,13"
"strandbias, many samples, low bq",UPN2_102,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),13282,715,14060,"0,0508534851",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"27,54","16,9"
"strandbias, many samples, low bq",UPN2_103,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),12992,722,13769,"0,052436633",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"27,59","16,88"
"strandbias, many samples, low bq",UPN2_104,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),15550,797,16404,"0,0485857108",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"27,62","16,85"
"strandbias, many samples, low bq",UPN2_105,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),13256,668,13973,"0,0478064839",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"27,51","17,51"
"strandbias, many samples, low bq",UPN2_106,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),20289,1056,21430,"0,0492767149",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"27,59","16,87"
"strandbias, many samples, low bq",UPN2_107,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),22810,1186,24102,"0,0492075346",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"27,62","16,94"
"strandbias, many samples, low bq",UPN2_108,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),18115,791,18993,"0,0416469226",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"27,54","16,76"
"strandbias, many samples, low bq",UPN2_109,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),18955,1048,20075,"0,0522042341",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"27,62","16,87"
"strandbias, many samples, low bq",UPN2_110,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),20746,1141,22010,"0,0518400727",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"27,54","17,18"
"strandbias, many samples, low bq",UPN2_111,21,36231843,T,G,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr181Pro/c.541A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),16487,910,17466,"0,0521012252",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,5",Deleterious,0,Damaging,"27,47","17,47"
"low bq, low freq, many artifacts, many samples",UPN2_059,21,36231848,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val179Gly/c.536T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),19215,215,19573,"0,0109845195",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"28,87","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_061,21,36231848,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val179Gly/c.536T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),18342,217,18711,"0,011597456",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"28,64","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_062,21,36231848,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val179Gly/c.536T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),16649,177,16938,"0,010449876",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"28,41","15,51"
"low bq, low freq, many artifacts, many samples",UPN2_063,21,36231848,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val179Gly/c.536T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),16931,176,17265,"0,0101940342",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"28,76","16,6"
"low bq, low freq, many artifacts, many samples",UPN2_065,21,36231848,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val179Gly/c.536T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),14714,167,14999,"0,0111340756",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"28,87","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_066,21,36231848,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val179Gly/c.536T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),17735,191,18066,"0,0105723458",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"28,89","15,9"
"low bq, low freq, many artifacts, many samples",UPN2_068,21,36231848,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val179Gly/c.536T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),18725,234,19132,"0,0122308175",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"28,39","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_069,21,36231848,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val179Gly/c.536T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),21264,220,21646,"0,0101635406",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"28,6","15,46"
"low bq, low freq, many artifacts, many samples",UPN2_070,21,36231848,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val179Gly/c.536T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),12939,174,13234,"0,0131479522",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"28,3","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_071,21,36231848,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val179Gly/c.536T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),15230,196,15582,"0,0125786164",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"28,77","16,47"
"low bq, low freq, many artifacts, many samples",UPN2_072,21,36231848,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val179Gly/c.536T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),17959,211,18290,"0,0115363587",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"28,64","15,5"
"low bq, low freq, many artifacts, many samples",UPN2_073,21,36231848,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val179Gly/c.536T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),16638,173,16933,"0,0102167365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"28,86","15,31"
"low bq, low freq, many artifacts, many samples",UPN2_074,21,36231848,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val179Gly/c.536T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),13385,139,13632,"0,0101965962",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"29,04","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_075,21,36231848,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val179Gly/c.536T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),22009,250,22442,"0,0111398271",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"29,27","15,42"
"low bq, low freq, many artifacts, many samples",UPN2_076,21,36231848,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val179Gly/c.536T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),17090,191,17413,"0,0109688164",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"28,4","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_077,21,36231848,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val179Gly/c.536T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),21003,260,21434,"0,0121302603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"28,65","15,84"
"low bq, low freq, many artifacts, many samples",UPN2_078,21,36231848,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val179Gly/c.536T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),18584,197,18950,"0,0103957784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"28,62","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_079,21,36231848,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val179Gly/c.536T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),12381,157,12660,"0,0124012638",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"28,66","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_080,21,36231848,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val179Gly/c.536T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),22666,238,23085,"0,0103097249",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"28,79","15,25"
"low bq, low freq, many artifacts, many samples",UPN2_081,21,36231848,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val179Gly/c.536T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),28170,309,28720,"0,0107590529",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"28,96","16,21"
"low bq, low freq, many artifacts, many samples",UPN2_082,21,36231848,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val179Gly/c.536T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),21543,247,21989,"0,0112328892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"28,9","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_083,21,36231848,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val179Gly/c.536T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),24092,249,24572,"0,0101334853",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"28,41","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_084,21,36231848,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val179Gly/c.536T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),20447,216,20815,"0,0103771319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"28,47","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_085,21,36231848,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val179Gly/c.536T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),17575,220,17956,"0,012252172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"28,74","15,56"
"low bq, low freq, many artifacts, many samples",UPN2_086,21,36231848,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val179Gly/c.536T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),11651,122,11862,"0,0102849435",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"28,56","15,95"
"low bq, low freq, many artifacts",UPN2_087,21,36231848,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val179Gly/c.536T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),23456,241,23883,"0,0100908596",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,57",Deleterious,0,Damaging,"28,78","15,25"
"low bq, low freq, many artifacts",UPN2_044,21,36231848,A,T,missense_variant(MODERATE|MISSENSE|gTc/gAc|p.Val179Asp/c.536T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|6|T),6322,65,6422,"0,0101214575",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,63",Deleterious,0,Damaging,"29,95","19,62"
"low bq, low freq, many artifacts",UPN2_064,21,36231852,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr178Pro/c.532A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),18375,193,18650,"0,0103485255",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,73",Deleterious,0,Damaging,"29,61","15,15"
"low bq, low freq, many artifacts",UPN2_068,21,36231855,T,G,missense_variant(MODERATE|MISSENSE|Atc/Ctc|p.Ile177Leu/c.529A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),18877,209,19161,"0,0109075727",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,88",Neutral,12,Damaging,"29,13","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_042,21,36231858,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr176Pro/c.526A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),30967,326,31497,"0,0103501921",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"29,2","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_043,21,36231858,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr176Pro/c.526A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),19588,221,19941,"0,0110826939",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"29,56","17,58"
"low bq, low freq, many artifacts, many samples",UPN2_044,21,36231858,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr176Pro/c.526A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),6325,69,6438,"0,0107176142",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"29,12","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_045,21,36231858,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr176Pro/c.526A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),21240,268,21623,"0,0123942099",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"29,2","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_046,21,36231858,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr176Pro/c.526A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),27185,286,27625,"0,0103529412",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"29,07","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_048,21,36231858,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr176Pro/c.526A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),33842,353,34392,"0,0102640149",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"29,09","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_049,21,36231858,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr176Pro/c.526A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),24359,252,24758,"0,0101785282",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"29,19","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_052,21,36231858,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr176Pro/c.526A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),20612,227,20979,"0,0108203442",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"29,06","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_053,21,36231858,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr176Pro/c.526A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),28609,304,29082,"0,0104532013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"29,07","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_054,21,36231858,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr176Pro/c.526A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),19576,220,19940,"0,0110330993",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"29,01",15
"low bq, low freq, many artifacts, many samples",UPN2_057,21,36231858,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr176Pro/c.526A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),26157,283,26583,"0,0106459015",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"29,16","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_059,21,36231858,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr176Pro/c.526A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),19089,420,19610,"0,0214176441",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"28,09","14,62"
"low bq, many samples",UPN2_060,21,36231858,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr176Pro/c.526A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),18964,494,19556,"0,0252607895",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"28,02","14,81"
"low bq, many samples",UPN2_061,21,36231858,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr176Pro/c.526A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),18214,457,18769,"0,02434866",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"27,75","14,8"
"low bq, many samples",UPN2_062,21,36231858,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr176Pro/c.526A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),16415,434,16966,"0,0255805729",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"27,74","15,3"
"low bq, many samples",UPN2_063,21,36231858,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr176Pro/c.526A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),16804,447,17312,"0,0258202403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"28,05","15,02"
"low bq, many samples",UPN2_064,21,36231858,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr176Pro/c.526A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),18142,454,18683,"0,0243001659",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"27,91","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_065,21,36231858,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr176Pro/c.526A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),14619,327,15035,"0,0217492517",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"27,96","14,29"
"low bq, many samples",UPN2_066,21,36231858,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr176Pro/c.526A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),17594,417,18102,"0,0230361286",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"28,09","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_067,21,36231858,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr176Pro/c.526A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),22151,481,22731,"0,0211605297",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"28,32","14,95"
"low bq, many samples",UPN2_068,21,36231858,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr176Pro/c.526A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),18594,466,19169,"0,024310084",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"27,75","14,9"
"low bq, many samples",UPN2_069,21,36231858,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr176Pro/c.526A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),21108,494,21706,"0,0227586842",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"27,77",15
"low bq, many samples",UPN2_070,21,36231858,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr176Pro/c.526A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),12876,342,13276,"0,0257607713",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"27,65","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_071,21,36231858,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr176Pro/c.526A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),15213,331,15616,"0,021196209",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"28,02","14,63"
"low bq, many samples",UPN2_072,21,36231858,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr176Pro/c.526A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),17788,442,18326,"0,0241187384",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"27,9","14,69"
"low bq, many samples",UPN2_073,21,36231858,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr176Pro/c.526A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),16498,407,16973,"0,0239792612",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"28,04","15,06"
"low bq, many samples",UPN2_074,21,36231858,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr176Pro/c.526A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),13294,306,13665,"0,0223929748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"28,11","15,23"
"low bq, low freq, many artifacts, many samples",UPN2_075,21,36231858,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr176Pro/c.526A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),21893,467,22479,"0,0207749455",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"28,36","15,4"
"low bq, many samples",UPN2_076,21,36231858,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr176Pro/c.526A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),16935,423,17469,"0,0242143225",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"27,7","14,46"
"low bq, many samples",UPN2_077,21,36231858,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr176Pro/c.526A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),20868,530,21489,"0,0246637815",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"27,78","14,82"
"low bq, many samples",UPN2_078,21,36231858,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr176Pro/c.526A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),18409,492,18991,"0,0259070086",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"27,69","14,59"
"low bq, many samples",UPN2_079,21,36231858,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr176Pro/c.526A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),12309,321,12699,"0,0252775809",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"27,91","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_080,21,36231858,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr176Pro/c.526A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),22536,502,23142,"0,0216921614",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"27,92","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_081,21,36231858,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr176Pro/c.526A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),28032,627,28783,"0,0217836918",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"28,08","14,9"
"low bq, many samples",UPN2_082,21,36231858,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr176Pro/c.526A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),21465,491,22046,"0,0222716139",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"28,12","14,85"
"low bq, many samples",UPN2_083,21,36231858,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr176Pro/c.526A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),23958,558,24640,"0,0226461039",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"27,77","14,23"
"low bq, many samples",UPN2_084,21,36231858,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr176Pro/c.526A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),20267,505,20866,"0,0242020512",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"27,83","14,53"
"low bq, many samples",UPN2_085,21,36231858,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr176Pro/c.526A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),17513,408,17995,"0,0226729647",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"27,86","14,6"
"low bq, many samples",UPN2_086,21,36231858,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr176Pro/c.526A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),11562,287,11901,"0,0241156205",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"27,68","15,08"
"low bq, many samples",UPN2_087,21,36231858,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr176Pro/c.526A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),23196,585,23944,"0,024432008",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"28,16","14,67"
"low bq, low freq, many artifacts",UPN2_088,21,36231858,T,G,missense_variant(MODERATE|MISSENSE|Acc/Ccc|p.Thr176Pro/c.526A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),15991,306,16387,"0,0186733386",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,7",Deleterious,0,Damaging,"28,49","14,68"
"low freq, many artifacts",UPN2_092,21,36231860,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu175Gln/c.524T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|6|T),6400,65,6494,"0,0100092393",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,63",Deleterious,0,Damaging,"33,13","32,69"
"low bq, low freq, many artifacts, many samples",UPN2_059,21,36231864,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr174Pro/c.520A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),19288,226,19623,"0,0115170973",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,56",Deleterious,0,Damaging,"28,6","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_060,21,36231864,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr174Pro/c.520A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),19217,251,19572,"0,0128244431",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,56",Deleterious,0,Damaging,"28,58","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_061,21,36231864,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr174Pro/c.520A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),18438,261,18785,"0,0138940644",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,56",Deleterious,0,Damaging,"28,25","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_062,21,36231864,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr174Pro/c.520A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),16573,260,16971,"0,0153202522",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,56",Deleterious,0,Damaging,"28,09","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_063,21,36231864,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr174Pro/c.520A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),16965,224,17318,"0,012934519",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,56",Deleterious,0,Damaging,"28,42","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_064,21,36231864,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr174Pro/c.520A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),18337,227,18688,"0,0121468322",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,56",Deleterious,0,Damaging,"28,34","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_065,21,36231864,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr174Pro/c.520A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),14765,188,15046,"0,0124950153",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,56",Deleterious,0,Damaging,"28,59","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_066,21,36231864,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr174Pro/c.520A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),17768,235,18114,"0,0129733907",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,56",Deleterious,0,Damaging,"28,65","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_067,21,36231864,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr174Pro/c.520A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),22367,264,22737,"0,0116110305",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,56",Deleterious,0,Damaging,"29,07","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_068,21,36231864,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr174Pro/c.520A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),18807,256,19180,"0,0133472367",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,56",Deleterious,0,Damaging,"28,23","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_069,21,36231864,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr174Pro/c.520A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),21294,288,21723,"0,0132578373",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,56",Deleterious,0,Damaging,"28,29","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_070,21,36231864,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr174Pro/c.520A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),13025,168,13284,"0,0126467931",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,56",Deleterious,0,Damaging,"28,11","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_071,21,36231864,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr174Pro/c.520A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),15362,178,15624,"0,0113927291",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,56",Deleterious,0,Damaging,"28,54","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_072,21,36231864,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr174Pro/c.520A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),17964,268,18337,"0,0146152588",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,56",Deleterious,0,Damaging,"28,43","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_073,21,36231864,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr174Pro/c.520A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),16683,213,16991,"0,0125360485",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,56",Deleterious,0,Damaging,"28,51","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_074,21,36231864,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr174Pro/c.520A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),13426,184,13672,"0,0134581627",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,56",Deleterious,0,Damaging,"28,51","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_075,21,36231864,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr174Pro/c.520A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),22101,268,22487,"0,0119179971",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,56",Deleterious,0,Damaging,"29,01","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_076,21,36231864,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr174Pro/c.520A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),17133,229,17476,"0,0131036851",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,56",Deleterious,0,Damaging,"28,24","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_077,21,36231864,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr174Pro/c.520A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),21099,278,21506,"0,0129266251",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,56",Deleterious,0,Damaging,"28,24","15,17"
"low bq, low freq, many artifacts, many samples",UPN2_078,21,36231864,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr174Pro/c.520A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),18681,226,19006,"0,0118909818",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,56",Deleterious,0,Damaging,"28,14","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_079,21,36231864,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr174Pro/c.520A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),12502,151,12705,"0,0118850846",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,56",Deleterious,0,Damaging,"28,43","15,14"
"low bq, low freq, many artifacts, many samples",UPN2_080,21,36231864,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr174Pro/c.520A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),22733,285,23150,"0,0123110151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,56",Deleterious,0,Damaging,"28,48","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_081,21,36231864,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr174Pro/c.520A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),28271,342,28799,"0,0118754123",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,56",Deleterious,0,Damaging,"28,67","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_082,21,36231864,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr174Pro/c.520A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),21660,266,22058,"0,0120591169",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,56",Deleterious,0,Damaging,"28,75","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_083,21,36231864,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr174Pro/c.520A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),24178,309,24649,"0,0125360055",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,56",Deleterious,0,Damaging,"28,22","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_084,21,36231864,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr174Pro/c.520A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),20499,276,20876,"0,0132209235",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,56",Deleterious,0,Damaging,"28,27","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_085,21,36231864,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr174Pro/c.520A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),17697,219,18010,"0,0121599112",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,56",Deleterious,0,Damaging,"28,36","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_086,21,36231864,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr174Pro/c.520A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),11688,149,11913,"0,0125073449",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,56",Deleterious,0,Damaging,"28,13","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_087,21,36231864,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr174Pro/c.520A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),23514,296,23952,"0,0123580494",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,56",Deleterious,0,Damaging,"28,54","14,81"
"low bq, low freq, many artifacts",UPN2_088,21,36231864,T,G,missense_variant(MODERATE|MISSENSE|Act/Cct|p.Thr174Pro/c.520A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|6|G),16099,180,16389,"0,0109829764",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,56",Deleterious,0,Damaging,"29,17","15,84"
"low bq, low freq, many artifacts, many samples",UPN2_059,21,36231866,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe173Cys/c.518T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),19238,220,19627,"0,0112090488",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,51",Deleterious,0,Damaging,"28,59","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_060,21,36231866,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe173Cys/c.518T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),19199,224,19584,"0,0114379085",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,51",Deleterious,0,Damaging,"28,6","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_061,21,36231866,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe173Cys/c.518T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),18402,237,18789,"0,0126137634",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,51",Deleterious,0,Damaging,"28,27","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_062,21,36231866,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe173Cys/c.518T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),16591,218,16973,"0,0128439286",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,51",Deleterious,0,Damaging,"28,08","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_063,21,36231866,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe173Cys/c.518T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),16998,187,17319,"0,0107973901",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,51",Deleterious,0,Damaging,"28,39","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_064,21,36231866,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe173Cys/c.518T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),18280,250,18689,"0,0133768527",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,51",Deleterious,0,Damaging,"28,52","14,67"
"low bq, low freq, many artifacts, many samples",UPN2_065,21,36231866,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe173Cys/c.518T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),14728,195,15047,"0,0129593939",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,51",Deleterious,0,Damaging,"28,54","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_066,21,36231866,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe173Cys/c.518T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),17780,186,18116,"0,0102671671",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,51",Deleterious,0,Damaging,"28,63","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_068,21,36231866,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe173Cys/c.518T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),18761,263,19185,"0,0137086265",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,51",Deleterious,0,Damaging,"28,24","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_069,21,36231866,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe173Cys/c.518T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),21259,285,21723,"0,0131197348",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,51",Deleterious,0,Damaging,"28,25","15,56"
"low bq, low freq, many artifacts, many samples",UPN2_070,21,36231866,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe173Cys/c.518T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),12978,199,13288,"0,0149759181",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,51",Deleterious,0,Damaging,"28,04","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_071,21,36231866,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe173Cys/c.518T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),15330,164,15628,"0,0104939852",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,51",Deleterious,0,Damaging,"28,58","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_072,21,36231866,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe173Cys/c.518T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),18005,202,18345,"0,0110111747",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,51",Deleterious,0,Damaging,"28,42","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_073,21,36231866,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe173Cys/c.518T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),16680,187,16989,"0,0110071223",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,51",Deleterious,0,Damaging,"28,59","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_074,21,36231866,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe173Cys/c.518T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),13377,171,13675,"0,0125045704",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,51",Deleterious,0,Damaging,"28,6","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_075,21,36231866,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe173Cys/c.518T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),22079,226,22494,"0,0100471237",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,51",Deleterious,0,Damaging,"28,98","15,46"
"low bq, low freq, many artifacts, many samples",UPN2_076,21,36231866,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe173Cys/c.518T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),17107,237,17479,"0,0135591281",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,51",Deleterious,0,Damaging,"28,14","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_077,21,36231866,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe173Cys/c.518T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),21085,249,21508,"0,0115770876",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,51",Deleterious,0,Damaging,"28,23","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_078,21,36231866,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe173Cys/c.518T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),18642,230,19010,"0,0120988953",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,51",Deleterious,0,Damaging,"28,04","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_079,21,36231866,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe173Cys/c.518T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),12462,148,12710,"0,0116443745",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,51",Deleterious,0,Damaging,"28,25","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_080,21,36231866,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe173Cys/c.518T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),22718,281,23156,"0,0121350838",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,51",Deleterious,0,Damaging,"28,48","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_081,21,36231866,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe173Cys/c.518T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),28219,348,28804,"0,0120816553",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,51",Deleterious,0,Damaging,"28,7","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_082,21,36231866,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe173Cys/c.518T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),21679,237,22062,"0,0107424531",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,51",Deleterious,0,Damaging,"28,58","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_083,21,36231866,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe173Cys/c.518T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),24141,311,24652,"0,0126156093",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,51",Deleterious,0,Damaging,"28,13","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_084,21,36231866,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe173Cys/c.518T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),20396,283,20879,"0,013554289",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,51",Deleterious,0,Damaging,"28,15","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_085,21,36231866,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe173Cys/c.518T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),17636,226,18013,"0,0125464942",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,51",Deleterious,0,Damaging,"28,29","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_086,21,36231866,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe173Cys/c.518T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),11668,130,11914,"0,0109115327",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,51",Deleterious,0,Damaging,"28,09","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_087,21,36231866,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe173Cys/c.518T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),23477,268,23959,"0,0111857757",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,51",Deleterious,0,Damaging,"28,38","15,15"
"low bq, low freq, many artifacts",UPN2_088,21,36231866,A,C,missense_variant(MODERATE|MISSENSE|tTc/tGc|p.Phe173Cys/c.518T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),16060,174,16393,"0,0106142866",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,51",Deleterious,0,Damaging,"29,06","15,02"
"many samples, low freq, many artifacts",UPN2_016,21,36231870,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser172Gly/c.514A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),11888,144,12074,"0,0119264535",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,82",Deleterious,0,Damaging,"31,19","31,97"
"many samples, low freq, many artifacts",UPN2_022,21,36231870,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser172Gly/c.514A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),18021,187,18273,"0,0102336781",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,82",Deleterious,0,Damaging,"30,38","32,54"
"many samples, low freq, many artifacts",UPN2_041,21,36231870,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser172Gly/c.514A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),21302,286,21708,"0,0131748664",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,82",Deleterious,0,Damaging,"30,51","31,37"
"many samples, low freq, many artifacts",UPN2_024,21,36231870,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser172Gly/c.514A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),7978,92,8090,"0,0113720643",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,82",Deleterious,0,Damaging,"30,43","32,08"
"many samples, low freq, many artifacts",UPN2_026,21,36231870,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser172Gly/c.514A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),20324,237,20625,"0,0114909091",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,82",Deleterious,0,Damaging,"30,08","31,51"
"many samples, low freq, many artifacts",UPN2_042,21,36231870,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser172Gly/c.514A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),31011,317,31528,"0,0100545547",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,82",Deleterious,0,Damaging,"30,45","31,05"
"many samples, low freq, many artifacts",UPN2_028,21,36231870,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser172Gly/c.514A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),17054,183,17292,"0,0105829285",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,82",Deleterious,0,Damaging,"30,01","31,23"
"many samples, low freq, many artifacts",UPN2_043,21,36231870,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser172Gly/c.514A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),19632,228,19960,"0,0114228457",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,82",Deleterious,0,Damaging,"30,91","31,97"
"many samples, low freq, many artifacts",UPN2_046,21,36231870,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser172Gly/c.514A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),27186,326,27651,"0,0117898087",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,82",Deleterious,0,Damaging,"30,28","30,36"
"many samples, low freq, many artifacts",UPN2_048,21,36231870,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser172Gly/c.514A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),33832,369,34424,"0,0107192656",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,82",Deleterious,0,Damaging,"30,43","31,3"
"many samples, low freq, many artifacts",UPN2_050,21,36231870,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser172Gly/c.514A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),23031,260,23407,"0,0111077883",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,82",Deleterious,0,Damaging,"30,43","31,64"
"many samples, low freq, many artifacts",UPN2_051,21,36231870,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser172Gly/c.514A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),22917,259,23294,"0,011118743",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,82",Deleterious,0,Damaging,"30,87","31,62"
"many samples, low freq, many artifacts",UPN2_052,21,36231870,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser172Gly/c.514A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),20677,216,21002,"0,0102847348",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,82",Deleterious,0,Damaging,"30,29","31,81"
"many samples, low freq, many artifacts",UPN2_054,21,36231870,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser172Gly/c.514A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),19580,254,19958,"0,0127267261",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,82",Deleterious,0,Damaging,"30,24","31,93"
"many samples, low freq, many artifacts",UPN2_055,21,36231870,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser172Gly/c.514A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),27824,327,28307,"0,011551913",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,82",Deleterious,0,Damaging,"30,42","31,88"
"many samples, low freq, many artifacts",UPN2_057,21,36231870,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser172Gly/c.514A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),26153,294,26610,"0,011048478",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,82",Deleterious,0,Damaging,"30,45","31,13"
"many samples, low freq, many artifacts",UPN2_058,21,36231870,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser172Gly/c.514A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),23918,302,24351,"0,0124019547",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,82",Deleterious,0,Damaging,"30,97","32,04"
"many samples, low freq, many artifacts",UPN2_093,21,36231870,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser172Gly/c.514A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),9071,95,9189,"0,0103384481",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,82",Deleterious,0,Damaging,"32,64","32,18"
"many samples, low freq, many artifacts",UPN2_087,21,36231870,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser172Gly/c.514A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),23511,245,23974,"0,0102194044",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,82",Deleterious,0,Damaging,"29,35","31,04"
"many samples, low freq, many artifacts",UPN2_095,21,36231870,T,C,missense_variant(MODERATE|MISSENSE|Agc/Ggc|p.Ser172Gly/c.514A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|6|C),13641,145,13844,"0,0104738515",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,82",Deleterious,0,Damaging,"32,08","33,06"
"low bq, low freq, many artifacts, many samples",UPN2_059,21,36252900,C,G,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln154His/c.462G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|5|G),3163,41,3218,"0,0127408328",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-4,61",Deleterious,9,Damaging,"30,64","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_060,21,36252900,C,G,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln154His/c.462G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|5|G),16328,201,16626,"0,0120894984",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-4,61",Deleterious,9,Damaging,"30,56","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_061,21,36252900,C,G,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln154His/c.462G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|5|G),15022,191,15273,"0,0125057291",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-4,61",Deleterious,9,Damaging,"30,79","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_063,21,36252900,C,G,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln154His/c.462G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|5|G),9121,101,9266,"0,0109000648",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-4,61",Deleterious,9,Damaging,"30,69",15
"low bq, low freq, many artifacts, many samples",UPN2_064,21,36252900,C,G,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln154His/c.462G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|5|G),2450,37,2498,"0,0148118495",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-4,61",Deleterious,9,Damaging,"30,53","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_065,21,36252900,C,G,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln154His/c.462G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|5|G),7591,97,7708,"0,012584328",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-4,61",Deleterious,9,Damaging,"30,51","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_066,21,36252900,C,G,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln154His/c.462G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|5|G),37711,469,38349,"0,0122297843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-4,61",Deleterious,9,Damaging,"30,65","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_067,21,36252900,C,G,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln154His/c.462G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|5|G),42290,622,43101,"0,0144312197",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-4,61",Deleterious,9,Damaging,"30,61","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_068,21,36252900,C,G,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln154His/c.462G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|5|G),22939,284,23371,"0,0121518121",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-4,61",Deleterious,9,Damaging,"30,69","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_069,21,36252900,C,G,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln154His/c.462G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|5|G),24612,302,25017,"0,0120717912",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-4,61",Deleterious,9,Damaging,"30,64","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_070,21,36252900,C,G,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln154His/c.462G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|5|G),14484,201,14739,"0,0136372888",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-4,61",Deleterious,9,Damaging,"30,68","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_071,21,36252900,C,G,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln154His/c.462G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|5|G),9408,142,9599,"0,0147932076",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-4,61",Deleterious,9,Damaging,"30,65","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_072,21,36252900,C,G,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln154His/c.462G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|5|G),7856,101,8002,"0,0126218445",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-4,61",Deleterious,9,Damaging,"30,62","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_073,21,36252900,C,G,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln154His/c.462G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|5|G),5915,90,6024,"0,014940239",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-4,61",Deleterious,9,Damaging,"30,48","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_074,21,36252900,C,G,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln154His/c.462G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|5|G),17516,221,17805,"0,0124122438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-4,61",Deleterious,9,Damaging,"30,67","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_075,21,36252900,C,G,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln154His/c.462G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|5|G),20485,260,20826,"0,0124843945",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-4,61",Deleterious,9,Damaging,"30,55","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_076,21,36252900,C,G,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln154His/c.462G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|5|G),20058,245,20399,"0,0120103927",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-4,61",Deleterious,9,Damaging,"30,74","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_077,21,36252900,C,G,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln154His/c.462G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|5|G),24363,286,24748,"0,0115564894",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-4,61",Deleterious,9,Damaging,"30,68","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_078,21,36252900,C,G,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln154His/c.462G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|5|G),15862,219,16153,"0,013557853",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-4,61",Deleterious,9,Damaging,"30,77","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_079,21,36252900,C,G,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln154His/c.462G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|5|G),11781,167,12000,"0,0139166667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-4,61",Deleterious,9,Damaging,"30,62","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_080,21,36252900,C,G,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln154His/c.462G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|5|G),12541,155,12752,"0,0121549561",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-4,61",Deleterious,9,Damaging,"30,72","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_081,21,36252900,C,G,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln154His/c.462G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|5|G),3964,42,4019,"0,0104503608",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-4,61",Deleterious,9,Damaging,"30,63","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_082,21,36252900,C,G,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln154His/c.462G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|5|G),32215,428,32808,"0,0130455986",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-4,61",Deleterious,9,Damaging,"30,64","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_083,21,36252900,C,G,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln154His/c.462G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|5|G),24467,289,24856,"0,0116269714",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-4,61",Deleterious,9,Damaging,"30,83","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_084,21,36252900,C,G,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln154His/c.462G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|5|G),19687,266,20040,"0,0132734531",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-4,61",Deleterious,9,Damaging,"30,66","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_085,21,36252900,C,G,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln154His/c.462G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|5|G),40265,515,41015,"0,0125563818",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-4,61",Deleterious,9,Damaging,"30,68","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_086,21,36252900,C,G,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln154His/c.462G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|5|G),38406,481,39056,"0,0123156493",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-4,61",Deleterious,9,Damaging,"30,71","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_087,21,36252900,C,G,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln154His/c.462G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|5|G),32944,468,33558,"0,0139460039",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-4,61",Deleterious,9,Damaging,"30,54","14,5"
"low bq, low freq, many artifacts",UPN2_088,21,36252900,C,G,missense_variant(MODERATE|MISSENSE|caG/caC|p.Gln154His/c.462G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|5|G),24325,329,24754,"0,0132907813",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,"8,24E-006",NO,NO,"-4,61",Deleterious,9,Damaging,"30,69","14,57"
"low freq, many artifacts",UPN2_056,21,36252901,TG,T,frameshift_variant(HIGH||cag/|p.Gln154fs/c.460delC|480|RUNX1|protein_coding|CODING|ENST00000437180|5|T),959,22,986,"0,0223123732",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,75",NA
"low freq, many artifacts",UPN2_044,21,36252902,G,T,missense_variant(MODERATE|MISSENSE|Cag/Aag|p.Gln154Lys/c.460C>A|480|RUNX1|protein_coding|CODING|ENST00000437180|5|T),4215,123,4357,"0,0282304338",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,69",Deleterious,"0,002",Damaging,"32,65","32,78"
"low freq, many artifacts",UPN2_006,21,36252907,T,C,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys152Arg/c.455A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|5|C),4676,54,4740,"0,0113924051",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,75",Deleterious,"0,007",Damaging,"34,34","33,09"
"low bq, low freq, many artifacts",UPN2_044,21,36252922,G,T,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala147Asp/c.440C>A|480|RUNX1|protein_coding|CODING|ENST00000437180|5|T),4308,50,4366,"0,0114521301",0,0,0,0,1,0,0,1,2,NO,NO,COSM25771,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-5,38",Deleterious,"0,004",Damaging,"33,75","27,6"
"low freq, many artifacts",UPN2_044,21,36252941,A,T,missense_variant(MODERATE|MISSENSE|Tcg/Acg|p.Ser141Thr/c.421T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|5|T),4271,79,4370,"0,0180778032",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,82",Deleterious,"0,07",Tolerated,"34,46","30,89"
"low freq, many artifacts",UPN2_044,21,36252967,A,G,missense_variant(MODERATE|MISSENSE|gTg/gCg|p.Val132Ala/c.395T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|5|G),4308,44,4370,"0,0100686499",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,0,Damaging,"33,15",32
"low bq, low freq, many artifacts",UPN2_081,21,36252973,A,C,missense_variant(MODERATE|MISSENSE|gTc/gGc|p.Val130Gly/c.389T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|5|C),3944,73,4035,"0,0180916976",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,23",Deleterious,2,Damaging,"31,35","17,38"
"low freq, many artifacts",UPN2_006,21,36252991,A,G,missense_variant(MODERATE|MISSENSE|gTt/gCt|p.Val124Ala/c.371T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|5|G),2323,33,2359,"0,0139889784",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,53",Deleterious,"0,008",Damaging,"35,28","35,76"
"low freq, many artifacts",UPN2_006,21,36253004,C,T,missense_variant(MODERATE|MISSENSE|Gcc/Acc|p.Ala120Thr/c.358G>A|480|RUNX1|protein_coding|CODING|ENST00000437180|5|T),2313,41,2359,"0,0173802459",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,56",Deleterious,"0,001",Damaging,"35,25","34,63"
"low bq, low freq, many artifacts, many samples",UPN2_044,21,36253009,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val118Glu/c.353T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|5|T),2134,22,2164,"0,0101663586",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,0,Damaging,"35,06","25,82"
"low bq, low freq, many artifacts, many samples",UPN2_050,21,36253009,A,T,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val118Glu/c.353T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|5|T),12722,130,12900,"0,0100775194",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,95",Deleterious,0,Damaging,"35,03","26,68"
"low freq, many artifacts",UPN2_056,21,36259175,A,T,missense_variant(MODERATE|MISSENSE|Tgg/Agg|p.Trp106Arg/c.316T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|4|T),4846,70,4939,"0,0141729095",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-10,09",Deleterious,0,Damaging,"34,74","35,47"
"low freq, many artifacts",UPN2_094,21,36259186,A,G,missense_variant(MODERATE|MISSENSE|cTg/cCg|p.Leu102Pro/c.305T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),4141,102,4250,"0,024",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,1",Deleterious,0,Damaging,"34,26","35,55"
"low freq, many artifacts",UPN2_097,21,36259186,A,G,missense_variant(MODERATE|MISSENSE|cTg/cCg|p.Leu102Pro/c.305T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),5562,144,5712,"0,025210084",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,1",Deleterious,0,Damaging,"34,39","35,35"
"low freq, many artifacts",UPN2_105,21,36259186,A,G,missense_variant(MODERATE|MISSENSE|cTg/cCg|p.Leu102Pro/c.305T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),3257,43,3304,"0,0130145278",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,1",Deleterious,0,Damaging,"34,39","34,98"
"low freq, many artifacts",UPN2_090,21,36259189,A,G,missense_variant(MODERATE|MISSENSE|gTg/gCg|p.Val101Ala/c.302T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),5049,86,5144,"0,016718507",0,0,0,0,1,1,0,1,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,64",Deleterious,"0,123",Tolerated,"30,79","35,21"
"low freq, many artifacts",UPN2_091,21,36259189,A,G,missense_variant(MODERATE|MISSENSE|gTg/gCg|p.Val101Ala/c.302T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),4145,46,4203,"0,0109445634",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,64",Deleterious,"0,123",Tolerated,"30,71","34,48"
"low freq, many artifacts",UPN2_044,21,36259203,G,T,missense_variant(MODERATE|MISSENSE|aaC/aaA|p.Asn96Lys/c.288C>A|480|RUNX1|protein_coding|CODING|ENST00000437180|4|T),3364,51,3425,"0,0148905109",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,"0,003",Damaging,"35,4","34,43"
"low bq, many samples",UPN2_001,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),3892,740,4651,"0,1591055687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,4,Damaging,"27,37","16,27"
"low bq, many samples",UPN2_014,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),8565,2584,11201,"0,2306936881",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"28,46","16,4"
"low bq, many samples",UPN2_015,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),13245,4240,17579,"0,2411968826",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"28,66","16,44"
"low bq, many samples",UPN2_016,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),6012,1812,7845,"0,2309751434",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,4,Damaging,"28,47","16,04"
"low bq, many samples",UPN2_017,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),4047,1275,5339,"0,2388087657",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"28,66","16,38"
"low bq, many samples",UPN2_018,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),6355,2036,8421,"0,2417765111",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,4,Damaging,"28,64","16,32"
"low bq, many samples",UPN2_019,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),6775,2157,8972,"0,2404146233",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"28,67","16,19"
"low bq, many samples",UPN2_020,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),5992,1915,7923,"0,2417013757",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"28,69","16,48"
"low bq, many samples",UPN2_021,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),6531,1922,8491,"0,2263573195",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,4,Damaging,"28,32","16,1"
"low bq, many samples",UPN2_002,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),4716,913,5642,"0,1618220489",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,4,Damaging,"27,4","15,66"
"low bq, many samples",UPN2_003,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1086,213,1299,"0,1639722864",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,4,Damaging,"27,51","16,12"
"low bq, many samples",UPN2_022,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),8150,2693,10894,"0,2472002937",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"28,72","16,46"
"low bq, many samples",UPN2_023,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),9431,2932,12417,"0,2361278892",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"28,58","16,3"
"low bq, many samples",UPN2_041,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),39930,10592,50780,"0,2085860575",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"28,26","17,44"
"low bq, many samples",UPN2_024,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),4430,1367,5827,"0,2345975631",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"28,56","16,49"
"low bq, many samples",UPN2_025,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),11823,3630,15509,"0,2340576439",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"28,52","16,37"
"low bq, many samples",UPN2_026,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),11135,3669,14867,"0,2467881886",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"28,77","16,4"
"low bq, many samples",UPN2_004,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1247,269,1524,"0,1765091864",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"27,71","16,54"
"low bq, many samples",UPN2_027,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),9005,2911,11955,"0,243496445",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"28,69","16,48"
"low bq, many samples",UPN2_089,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),5449,2627,8099,"0,3243610322",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"30,57","22,89"
"low bq, many samples",UPN2_042,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),25721,6859,32760,"0,2093711844",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"28,32","17,31"
"low bq, many samples",UPN2_028,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),6284,2065,8376,"0,2465377268",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"28,71","16,31"
"low bq, many samples",UPN2_043,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),15799,4260,20172,"0,2111838192",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"28,35","17,43"
"low bq, many samples",UPN2_044,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),5231,1445,6726,"0,2148379423",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"28,34","17,15"
"low bq, many samples",UPN2_029,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),7889,2528,10464,"0,2415902141",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"28,75","16,38"
"low bq, many samples",UPN2_030,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),10876,3216,14165,"0,2270384751",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"28,5","16,3"
"low bq, many samples",UPN2_031,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),7310,2147,9501,"0,225976213",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"28,43","16,4"
"low bq, many samples",UPN2_005,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1512,306,1829,"0,167304538",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,4,Damaging,"27,35","15,86"
"low bq, many samples",UPN2_045,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),24013,6684,30830,"0,2168018164",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"28,36","17,43"
"low bq, many samples",UPN2_032,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),2409,721,3143,"0,2293986637",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,4,Damaging,"28,43","16,25"
"low bq, many samples",UPN2_046,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),15560,4281,19950,"0,2145864662",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"28,38","17,55"
"low bq, many samples",UPN2_033,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),6888,2035,8970,"0,2268673356",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"28,39","16,37"
"low bq, many samples",UPN2_034,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),2049,662,2724,"0,2430249633",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,4,Damaging,"28,69","16,25"
"low bq, many samples",UPN2_047,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),27156,7234,34572,"0,2092444753",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"28,32","17,46"
"low bq, many samples",UPN2_048,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),27493,6939,34557,"0,2007986804",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"28,14","17,55"
"low bq, many samples",UPN2_035,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),5916,1675,7638,"0,2192982456",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"28,3","16,47"
"low bq, many samples",UPN2_036,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),5073,1595,6690,"0,2384155456",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"28,75","16,26"
"low bq, many samples",UPN2_006,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),2683,454,3148,"0,1442185515",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"27,26","16,32"
"low bq, many samples",UPN2_049,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),11053,2844,13968,"0,2036082474",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"28,19","17,39"
"low bq, many samples",UPN2_050,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),14299,3954,18340,"0,2155943293",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"28,35","17,52"
"low bq, many samples",UPN2_037,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),15047,4773,19882,"0,2400663917",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"28,61","16,42"
"low bq, many samples",UPN2_051,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),13149,3362,16582,"0,2027499698",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,4,Damaging,"28,18","17,31"
"low bq, many samples",UPN2_052,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),13520,3808,17407,"0,2187625668",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"28,5","17,55"
"low bq, many samples",UPN2_038,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),17151,5330,22560,"0,2362588652",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"28,54","16,52"
"low bq, many samples",UPN2_039,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),6995,2223,9255,"0,2401944895",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"28,63","16,51"
"low bq, many samples",UPN2_053,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),17563,4892,22575,"0,2166998893",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"28,42","17,37"
"low bq, many samples",UPN2_054,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),9541,2634,12232,"0,2153368215",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"28,41","17,46"
"low bq, many samples",UPN2_007,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),11277,2006,13351,"0,1502509175",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"27,33","16,54"
"low bq, many samples",UPN2_008,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),21745,4046,25903,"0,1561981238",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"27,42","16,34"
"low bq, many samples",UPN2_009,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),17832,3315,21216,"0,15625",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"27,4","16,26"
"low bq, many samples",UPN2_010,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),8525,1544,10101,"0,1528561529",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,4,Damaging,"27,31","15,93"
"low bq, many samples",UPN2_011,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),10531,1938,12518,"0,1548170634",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"27,35","16,29"
"low bq, many samples",UPN2_055,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),21272,5694,27072,"0,2103280142",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"28,35","17,43"
"low bq, many samples",UPN2_056,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),7620,2057,9729,"0,2114297461",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"28,35","17,33"
"low bq, many samples",UPN2_090,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),6767,3270,10070,"0,3247269116",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"30,55","22,63"
"low bq, many samples",UPN2_057,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),10396,2751,13214,"0,2081882852",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"28,25","17,56"
"low bq, many samples",UPN2_058,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),8267,2158,10455,"0,206408417",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,4,Damaging,"28,2","17,35"
"low bq, many samples",UPN2_059,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),275,141,420,"0,3357142857",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"30,59","25,92"
low bq,UPN2_012,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),5657,1025,6700,"0,1529850746",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,4,Damaging,"27,4","16,33"
"low bq, many samples",UPN2_060,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),447,266,714,"0,3725490196",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"31,49","25,59"
"low bq, many samples",UPN2_040,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),2784,900,3694,"0,2436383324",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"28,81","16,47"
"low bq, many samples",UPN2_013,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),3410,599,4038,"0,1483407628",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"27,39","16,03"
"low bq, many samples",UPN2_091,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),5603,2613,8248,"0,3168040737",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"30,4","22,91"
"low bq, many samples",UPN2_092,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),2265,1132,3411,"0,3318674875",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"30,68","23,07"
"low bq, many samples",UPN2_093,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),2214,1049,3276,"0,3202075702",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"30,7","22,62"
"low bq, many samples",UPN2_061,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1615,906,2537,"0,3571147024",1,1,0,0,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"31,06","26,24"
"low bq, many samples",UPN2_062,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1011,571,1590,"0,3591194969",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"31,1","25,96"
"low bq, many samples",UPN2_063,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),391,233,628,"0,3710191083",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"31,44","26,13"
"low bq, many samples",UPN2_064,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),452,245,700,"0,35",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"30,89","25,6"
"low bq, many samples",UPN2_065,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),831,452,1286,"0,3514774495",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"31,29","25,13"
"low bq, many samples",UPN2_066,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),168,102,270,"0,3777777778",1,1,0,0,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"31,32","26,14"
"low bq, many samples",UPN2_067,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),108,57,165,"0,3454545455",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,31,"25,26"
"low bq, many samples",UPN2_068,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),388,220,610,"0,3606557377",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"31,27","26,26"
"low bq, many samples",UPN2_069,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),355,227,584,"0,3886986301",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"31,95","26,2"
"low bq, many samples",UPN2_070,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),229,129,358,"0,3603351955",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"31,03","26,74"
"low bq, many samples",UPN2_071,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1100,580,1687,"0,343805572",1,1,0,0,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"30,75","26,37"
"low bq, many samples",UPN2_072,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1199,657,1866,"0,3520900322",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"31,16","25,01"
"low bq, many samples",UPN2_073,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),355,188,549,"0,3424408015",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"30,95","25,69"
"low bq, many samples",UPN2_074,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),123,67,190,"0,3526315789",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"30,72","26,42"
"low bq, many samples",UPN2_075,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1088,578,1672,"0,3456937799",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"30,83","25,83"
"low bq, many samples",UPN2_076,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),560,329,893,"0,3684210526",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"31,45","25,73"
"low bq, many samples",UPN2_077,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),803,436,1244,"0,3504823151",1,1,0,0,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"31,2","26,1"
"low bq, many samples",UPN2_078,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),634,347,991,"0,3501513623",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"30,97","25,85"
"low bq, many samples",UPN2_079,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),298,169,469,"0,3603411514",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"31,33","26,2"
"low bq, many samples",UPN2_080,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1176,652,1832,"0,3558951965",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"31,13","25,7"
"low bq, many samples",UPN2_081,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1631,927,2567,"0,3611219322",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"31,36","25,38"
"low bq, many samples",UPN2_082,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),456,239,695,"0,3438848921",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"30,7","24,85"
"low bq, many samples",UPN2_083,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1002,550,1565,"0,3514376997",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"30,93","26,13"
"low bq, many samples",UPN2_084,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),903,534,1437,"0,3716075157",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"31,23","25,55"
"low bq, many samples",UPN2_085,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),466,251,723,"0,347164592",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"30,56","25,45"
"low bq, many samples",UPN2_086,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),99,57,156,"0,3653846154",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"31,17","26,18"
"low bq, many samples",UPN2_087,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),367,213,580,"0,3672413793",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"31,97","25,85"
"low bq, many samples",UPN2_088,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),265,164,429,"0,3822843823",1,1,0,0,1,0,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"31,51","25,55"
"low bq, many samples",UPN2_094,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),5599,2778,8408,"0,3303996194",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"30,66","22,97"
"low bq, many samples",UPN2_095,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),4981,2401,7407,"0,3241528284",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"30,56","22,68"
"low bq, many samples",UPN2_096,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),5356,2641,8024,"0,3291375872",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"30,71","22,98"
"low bq, many samples",UPN2_097,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),7643,3611,11284,"0,3200106345",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"30,47","22,6"
"low bq, many samples",UPN2_098,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),6257,2987,9286,"0,3216670256",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"30,53","22,65"
"low bq, many samples",UPN2_099,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),2703,1321,4046,"0,326495304",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"30,55","22,75"
"low bq, many samples",UPN2_100,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),4009,1648,5670,"0,2906525573",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"29,79","22,19"
"low bq, many samples",UPN2_101,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),4852,2478,7358,"0,3367762979",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"30,85","23,08"
"low bq, many samples",UPN2_102,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),4807,2388,7229,"0,3303361461",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"30,76","23,08"
"low bq, many samples",UPN2_103,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),4123,2071,6217,"0,3331188676",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"30,72","22,94"
"low bq, many samples",UPN2_104,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),4582,2273,6878,"0,330473975",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"30,7","22,78"
"low bq, many samples",UPN2_105,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),4415,2095,6526,"0,3210235979",0,1,0,0,1,0,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"30,54","22,76"
"low bq, many samples",UPN2_106,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),11116,5330,16496,"0,3231086324",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"30,52","22,72"
"low bq, many samples",UPN2_107,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),9256,4512,13803,"0,3268854597",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"30,65","22,82"
"low bq, many samples",UPN2_108,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),8532,3919,12486,"0,3138715361",0,1,0,0,1,1,0,0,3,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"30,25","22,48"
"low bq, many samples",UPN2_109,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),6914,3479,10401,"0,3344870686",1,1,0,0,1,1,0,0,4,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"30,78","22,75"
"low bq, many samples",UPN2_110,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),8555,4115,12721,"0,3234808584",1,1,0,0,1,1,0,0,4,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"30,53","22,99"
"low bq, many samples",UPN2_111,21,36259213,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp93Ala/c.278A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),6144,2900,9063,"0,3199823458",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,34",Deleterious,"0,004",Damaging,"30,46","22,74"
"low freq, many artifacts",UPN2_006,21,36259217,T,A,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr92Ser/c.274A>T|480|RUNX1|protein_coding|CODING|ENST00000437180|4|A),3088,47,3151,"0,0149158997",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,73",Deleterious,"0,003",Damaging,"30,48","29,6"
"low bq, bad alignment, many samples",UPN2_061,21,36259222,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val90Gly/c.269T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),2473,74,2578,"0,028704422",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,94",Deleterious,0,Damaging,"24,91","14,35"
"low bq, bad alignment, many samples",UPN2_062,21,36259222,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val90Gly/c.269T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1543,58,1612,"0,0359801489",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,94",Deleterious,0,Damaging,"24,65","15,17"
"low bq, bad alignment, many samples",UPN2_063,21,36259222,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val90Gly/c.269T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),603,27,634,"0,0425867508",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,94",Deleterious,0,Damaging,"25,14","15,96"
"low bq, bad alignment, many samples",UPN2_065,21,36259222,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val90Gly/c.269T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1260,44,1309,"0,0336134454",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,94",Deleterious,0,Damaging,"25,08","14,59"
"low bq, bad alignment, many samples",UPN2_071,21,36259222,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val90Gly/c.269T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1658,50,1716,"0,0291375291",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,94",Deleterious,0,Damaging,"24,62","14,66"
"low bq, bad alignment, many samples",UPN2_072,21,36259222,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val90Gly/c.269T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1820,61,1899,"0,0321221696",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,94",Deleterious,0,Damaging,"25,16","15,07"
"low bq, bad alignment, many samples",UPN2_075,21,36259222,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val90Gly/c.269T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1624,52,1693,"0,0307147076",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,94",Deleterious,0,Damaging,"25,14","14,13"
"low bq, bad alignment, many samples",UPN2_076,21,36259222,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val90Gly/c.269T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),870,32,908,"0,0352422907",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,94",Deleterious,0,Damaging,"24,57","14,56"
"low bq, bad alignment, many samples",UPN2_077,21,36259222,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val90Gly/c.269T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1218,42,1267,"0,0331491713",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,94",Deleterious,0,Damaging,"24,95","14,52"
"low bq, bad alignment, many samples",UPN2_078,21,36259222,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val90Gly/c.269T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),970,34,1011,"0,0336300692",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,94",Deleterious,0,Damaging,"24,83","14,53"
"low bq, bad alignment, many samples",UPN2_080,21,36259222,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val90Gly/c.269T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1782,64,1862,"0,0343716434",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,94",Deleterious,0,Damaging,"24,61","14,11"
"low bq, bad alignment, many samples",UPN2_081,21,36259222,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val90Gly/c.269T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),2523,71,2605,"0,0272552783",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,94",Deleterious,0,Damaging,"24,97","15,3"
"low bq, bad alignment, many samples",UPN2_082,21,36259222,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val90Gly/c.269T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),663,25,699,"0,0357653791",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,94",Deleterious,0,Damaging,"25,29","14,8"
"low bq, bad alignment, many samples",UPN2_083,21,36259222,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val90Gly/c.269T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1532,52,1589,"0,0327249843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,94",Deleterious,0,Damaging,"25,14","15,6"
"low bq, bad alignment, many samples",UPN2_084,21,36259222,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val90Gly/c.269T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1387,62,1454,"0,0426409904",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,94",Deleterious,0,Damaging,25,"14,56"
"low bq, bad alignment",UPN2_085,21,36259222,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val90Gly/c.269T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),701,24,728,"0,032967033",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,94",Deleterious,0,Damaging,"24,85","14,58"
"low freq, many artifacts",UPN2_083,21,36259222,AC,A,frameshift_variant(HIGH||gtg/|p.Val90fs/c.268delG|480|RUNX1|protein_coding|CODING|ENST00000437180|4|A),1561,20,1589,"0,0125865324",0,0,0,1,0,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,26",NA
"low bq, many samples",UPN2_061,21,36259225,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu89Arg/c.266T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),2513,57,2580,"0,0220930233",0,0,0,0,1,0,0,0,1,NO,NO,COSM211648,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-4,02",Deleterious,0,Damaging,"28,78","14,58"
"low bq, many samples",UPN2_062,21,36259225,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu89Arg/c.266T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1557,49,1613,"0,0303781773",0,0,0,0,1,0,0,0,1,NO,NO,COSM211648,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-4,02",Deleterious,0,Damaging,"28,96","15,61"
"low bq, low freq, many artifacts, many samples",UPN2_065,21,36259225,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu89Arg/c.266T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1269,27,1309,"0,0206264324",0,0,0,0,1,0,0,0,1,NO,NO,COSM211648,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-4,02",Deleterious,0,Damaging,"28,89","14,74"
"low bq, many samples",UPN2_071,21,36259225,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu89Arg/c.266T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1673,38,1717,"0,0221316249",0,0,0,0,1,0,0,0,1,NO,NO,COSM211648,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-4,02",Deleterious,0,Damaging,"28,83","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_072,21,36259225,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu89Arg/c.266T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1858,36,1899,"0,018957346",0,0,0,0,1,0,0,0,1,NO,NO,COSM211648,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-4,02",Deleterious,0,Damaging,"29,17","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_075,21,36259225,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu89Arg/c.266T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1661,30,1696,"0,0176886792",0,0,0,0,1,0,0,0,1,NO,NO,COSM211648,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-4,02",Deleterious,0,Damaging,"29,02",14
"low bq, low freq, many artifacts, many samples",UPN2_077,21,36259225,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu89Arg/c.266T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1234,23,1268,"0,0181388013",0,0,0,0,1,0,0,0,1,NO,NO,COSM211648,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-4,02",Deleterious,0,Damaging,"28,6","15,83"
"low bq, low freq, many artifacts, many samples",UPN2_078,21,36259225,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu89Arg/c.266T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),976,22,1013,"0,0217176703",0,0,0,0,1,0,0,0,1,NO,NO,COSM211648,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-4,02",Deleterious,0,Damaging,"28,58","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_080,21,36259225,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu89Arg/c.266T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1814,38,1862,"0,0204081633",0,0,0,0,1,0,0,0,1,NO,NO,COSM211648,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-4,02",Deleterious,0,Damaging,"28,53","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_081,21,36259225,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu89Arg/c.266T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),2548,53,2606,"0,0203376823",0,0,0,0,1,0,0,0,1,NO,NO,COSM211648,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-4,02",Deleterious,0,Damaging,"28,74","15,4"
"low bq, low freq, many artifacts, many samples",UPN2_083,21,36259225,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu89Arg/c.266T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1555,33,1589,"0,0207677785",0,0,0,0,1,0,0,0,1,NO,NO,COSM211648,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-4,02",Deleterious,0,Damaging,"28,83",14
"low bq, low freq, many artifacts, many samples",UPN2_084,21,36259225,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu89Arg/c.266T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1414,28,1455,"0,0192439863",0,0,0,0,1,0,0,0,1,NO,NO,COSM211648,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-4,02",Deleterious,0,Damaging,"28,56","15,04"
low bq,UPN2_085,21,36259225,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu89Arg/c.266T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),700,21,728,"0,0288461538",0,0,0,0,1,0,0,0,1,NO,NO,COSM211648,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-4,02",Deleterious,0,Damaging,"28,26","14,33"
"low bq, many samples",UPN2_061,21,36259228,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu88Ala/c.263A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),2514,61,2580,"0,0236434109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,15",Deleterious,1,Damaging,"28,18","14,33"
"low bq, many samples",UPN2_062,21,36259228,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu88Ala/c.263A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1554,53,1613,"0,0328580285",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,15",Deleterious,1,Damaging,"28,41","14,13"
"low bq, many samples",UPN2_065,21,36259228,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu88Ala/c.263A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1274,31,1309,"0,0236822002",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,15",Deleterious,1,Damaging,"28,41","14,65"
"low bq, many samples",UPN2_071,21,36259228,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu88Ala/c.263A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1675,38,1718,"0,0221187427",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,15",Deleterious,1,Damaging,"28,42","14,34"
"low bq, many samples",UPN2_072,21,36259228,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu88Ala/c.263A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1845,45,1899,"0,0236966825",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,15",Deleterious,1,Damaging,"28,36","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_075,21,36259228,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu88Ala/c.263A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1656,36,1696,"0,0212264151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,15",Deleterious,1,Damaging,"28,12","14,36"
"low bq, many samples",UPN2_076,21,36259228,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu88Ala/c.263A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),877,30,908,"0,0330396476",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,15",Deleterious,1,Damaging,"28,48","14,23"
"low bq, many samples",UPN2_077,21,36259228,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu88Ala/c.263A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1231,35,1268,"0,0276025237",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,15",Deleterious,1,Damaging,"28,53",14
"low bq, many samples",UPN2_078,21,36259228,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu88Ala/c.263A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),985,26,1013,"0,0256663376",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,15",Deleterious,1,Damaging,"28,3",14
"low bq, many samples",UPN2_080,21,36259228,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu88Ala/c.263A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1818,44,1862,"0,0236305048",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,15",Deleterious,1,Damaging,"28,22","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_081,21,36259228,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu88Ala/c.263A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),2534,55,2606,"0,021105142",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,15",Deleterious,1,Damaging,"28,43","14,33"
"low bq, many samples",UPN2_083,21,36259228,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu88Ala/c.263A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1537,41,1589,"0,0258023914",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,15",Deleterious,1,Damaging,"28,54","14,32"
"low bq, low freq, many artifacts",UPN2_084,21,36259228,T,G,missense_variant(MODERATE|MISSENSE|gAg/gCg|p.Glu88Ala/c.263A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1423,32,1455,"0,0219931271",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,15",Deleterious,1,Damaging,"28,43","14,41"
"low bq, low freq, many artifacts",UPN2_073,21,36259234,G,A,missense_variant(MODERATE|MISSENSE|cCg/cTg|p.Pro86Leu/c.257C>T|480|RUNX1|protein_coding|CODING|ENST00000437180|4|A),542,20,564,"0,0354609929",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,47",Deleterious,"0,042",Damaging,"32,72","28,2"
"low bq, low freq, many artifacts",UPN2_061,21,36259237,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His85Pro/c.254A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),2502,65,2580,"0,0251937984",1,0,0,0,1,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,39",Deleterious,0,Damaging,"27,07","14,31"
"low bq, many samples",UPN2_062,21,36259237,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His85Pro/c.254A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1558,42,1612,"0,0260545906",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,39",Deleterious,0,Damaging,"27,23","14,48"
"low bq, many samples",UPN2_065,21,36259237,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His85Pro/c.254A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1270,36,1310,"0,027480916",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,39",Deleterious,0,Damaging,"27,73","14,81"
"low bq, low freq, many artifacts",UPN2_071,21,36259237,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His85Pro/c.254A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1676,39,1718,"0,0227008149",1,0,0,0,1,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,39",Deleterious,0,Damaging,"27,23","14,64"
"low bq, low freq, many artifacts",UPN2_072,21,36259237,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His85Pro/c.254A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1843,51,1899,"0,0268562401",1,0,0,0,1,0,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,39",Deleterious,0,Damaging,"27,35","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_075,21,36259237,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His85Pro/c.254A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1658,28,1696,"0,016509434",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,39",Deleterious,0,Damaging,"27,83","15,11"
"low bq, bad alignment, many samples",UPN2_076,21,36259237,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His85Pro/c.254A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),871,31,908,"0,0341409692",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,39",Deleterious,0,Damaging,"26,96","14,23"
"low bq, many samples",UPN2_078,21,36259237,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His85Pro/c.254A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),987,24,1013,"0,0236920039",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,39",Deleterious,0,Damaging,"27,05","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_080,21,36259237,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His85Pro/c.254A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1818,35,1863,"0,0187869028",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,39",Deleterious,0,Damaging,"27,28","14,51"
"low bq, many samples",UPN2_081,21,36259237,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His85Pro/c.254A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),2535,62,2606,"0,023791251",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,39",Deleterious,0,Damaging,"27,4","14,85"
"low bq, many samples",UPN2_083,21,36259237,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His85Pro/c.254A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1543,38,1590,"0,0238993711",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,39",Deleterious,0,Damaging,"27,17","14,18"
many samples,UPN2_084,21,36259237,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His85Pro/c.254A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1411,36,1456,"0,0247252747",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,39",Deleterious,0,Damaging,27,"14,86"
"low bq, low freq, many artifacts",UPN2_101,21,36259237,T,G,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His85Pro/c.254A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),7290,82,7395,"0,0110885734",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,39",Deleterious,0,Damaging,"29,36","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_089,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),8026,97,8155,"0,0118945432",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"28,85","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_047,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),34191,349,34669,"0,0100666301",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"29,82","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_048,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),34209,351,34662,"0,0101263632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"29,76","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_049,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),13834,142,14038,"0,0101154011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"29,85","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_050,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),18132,184,18398,"0,0100010871",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"29,74","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_056,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),9621,101,9751,"0,010357912",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"29,78","15,74"
"low bq, low freq, many artifacts, many samples",UPN2_090,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),9935,149,10119,"0,0147247752",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"28,93","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_091,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),8162,117,8296,"0,0141031823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"28,95","14,41"
"low bq, low freq, many artifacts, many samples",UPN2_092,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),3380,45,3433,"0,0131080687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"28,96","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_093,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),3203,53,3274,"0,0161881491",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"29,14","14,74"
"low bq, bad alignment, many samples",UPN2_061,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),2471,104,2580,"0,0403100775",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"26,61","14,51"
"low bq, bad alignment, many samples",UPN2_062,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1529,80,1612,"0,0496277916",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"26,76","14,26"
"low bq, bad alignment, many samples",UPN2_063,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),609,23,637,"0,0361067504",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"26,76",16
"low bq, many samples",UPN2_064,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),672,37,711,"0,0520393812",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"27,06","14,73"
"low bq, many samples",UPN2_065,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1239,63,1309,"0,0481283422",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"27,26","14,67"
"low bq, bad alignment, many samples",UPN2_069,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),561,27,590,"0,0457627119",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"26,87",14
"low bq, bad alignment, many samples",UPN2_071,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1644,66,1718,"0,0384167637",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"26,78","14,82"
"low bq, many samples",UPN2_072,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1820,69,1900,"0,0363157895",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"27,02","14,36"
"low bq, bad alignment, many samples",UPN2_075,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1624,74,1698,"0,0435806832",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"26,98","14,45"
"low bq, bad alignment, many samples",UPN2_076,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),869,38,908,"0,0418502203",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"26,68","14,18"
"low bq, bad alignment, many samples",UPN2_077,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1226,40,1268,"0,0315457413",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"26,64",14
"low bq, bad alignment, many samples",UPN2_078,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),973,36,1013,"0,0355380059",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"26,56","14,61"
"low bq, bad alignment, many samples",UPN2_079,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),452,21,475,"0,0442105263",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"26,57","14,95"
"low bq, bad alignment, many samples",UPN2_080,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1774,83,1863,"0,0445517982",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"26,37","14,24"
"low bq, bad alignment, many samples",UPN2_081,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),2493,108,2607,"0,0414269275",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"26,96","14,73"
"low bq, many samples",UPN2_082,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),671,26,699,"0,0371959943",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"27,03","14,27"
"low bq, bad alignment, many samples",UPN2_083,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1527,57,1590,"0,0358490566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"26,66",14
"low bq, bad alignment, many samples",UPN2_084,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1383,69,1456,"0,0473901099",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"26,31","14,29"
"low bq, bad alignment, many samples",UPN2_085,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),688,42,730,"0,0575342466",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"26,58","14,31"
"low bq, bad alignment, many samples",UPN2_087,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),571,29,600,"0,0483333333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"26,82","14,24"
"low bq, low freq, many artifacts, many samples",UPN2_094,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),8301,130,8471,"0,0153464762",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"28,84","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_095,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),7295,117,7442,"0,0157215802",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"28,83","14,12"
"low bq, low freq, many artifacts, many samples",UPN2_096,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),7909,119,8066,"0,0147532854",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"28,96","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_097,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),11160,163,11351,"0,0143599683",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"28,88","14,87"
"low bq, low freq, many artifacts, many samples",UPN2_098,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),9193,132,9342,"0,0141297367",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"28,85",14
"low bq, low freq, many artifacts, many samples",UPN2_099,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),4009,63,4077,"0,0154525386",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"28,71","14,11"
"low bq, low freq, many artifacts, many samples",UPN2_100,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),5602,74,5697,"0,0129892926",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"29,17","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_101,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),7270,98,7395,"0,0132521974",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"28,68","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_102,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),7176,92,7293,"0,0126148361",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"28,82",14
"low bq, low freq, many artifacts, many samples",UPN2_103,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),6176,76,6263,"0,0121347597",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"28,8","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_104,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),6837,81,6926,"0,0116950621",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"28,91","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_105,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),6457,92,6570,"0,0140030441",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"28,76","15,25"
"low bq, low freq, many artifacts, many samples",UPN2_106,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),16366,207,16608,"0,0124638728",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"28,97","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_107,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),13679,186,13910,"0,0133716751",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"28,94","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_108,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),12351,155,12546,"0,0123545353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"29,02","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_109,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),10282,156,10473,"0,0148954454",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"28,91","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_110,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),12598,169,12814,"0,0131886999",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"28,88","14,42"
"low bq, low freq, many artifacts",UPN2_111,21,36259240,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp84Ala/c.251A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),8981,132,9136,"0,0144483363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,59",Deleterious,6,Damaging,"28,85","14,11"
"low bq, low freq, many artifacts, many samples",UPN2_061,21,36259246,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu82Arg/c.245T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),2498,45,2578,"0,0174553918",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,69",Deleterious,1,Damaging,"30,72",14
"low bq, low freq, many artifacts, many samples",UPN2_062,21,36259246,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu82Arg/c.245T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1556,32,1604,"0,0199501247",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,69",Deleterious,1,Damaging,"30,33","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_065,21,36259246,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu82Arg/c.245T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1275,24,1307,"0,0183626626",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,69",Deleterious,1,Damaging,"30,51","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_071,21,36259246,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu82Arg/c.245T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1677,30,1714,"0,0175029172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,69",Deleterious,1,Damaging,"30,42","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_072,21,36259246,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu82Arg/c.245T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1852,37,1896,"0,0195147679",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,69",Deleterious,1,Damaging,"30,34","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_075,21,36259246,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu82Arg/c.245T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1667,24,1695,"0,014159292",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,69",Deleterious,1,Damaging,"30,55","14,75"
"low bq, many samples",UPN2_076,21,36259246,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu82Arg/c.245T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),876,24,904,"0,0265486726",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,69",Deleterious,1,Damaging,"29,99","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_077,21,36259246,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu82Arg/c.245T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1238,22,1266,"0,0173775671",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,69",Deleterious,1,Damaging,"30,21","15,18"
"low bq, many samples",UPN2_078,21,36259246,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu82Arg/c.245T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),985,23,1011,"0,0227497527",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,69",Deleterious,1,Damaging,"30,02",14
"low bq, many samples",UPN2_080,21,36259246,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu82Arg/c.245T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1809,47,1860,"0,0252688172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,69",Deleterious,1,Damaging,"29,87","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_081,21,36259246,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu82Arg/c.245T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),2549,47,2605,"0,0180422265",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,69",Deleterious,1,Damaging,"30,24","15,7"
"low bq, many samples",UPN2_083,21,36259246,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu82Arg/c.245T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1545,38,1591,"0,0238843495",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,69",Deleterious,1,Damaging,"30,48","16,29"
"low bq, low freq, many artifacts, many samples",UPN2_084,21,36259246,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu82Arg/c.245T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1420,29,1455,"0,0199312715",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,69",Deleterious,1,Damaging,"30,03",14
low bq,UPN2_085,21,36259246,A,C,missense_variant(MODERATE|MISSENSE|cTg/cGg|p.Leu82Arg/c.245T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),708,20,730,"0,0273972603",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,69",Deleterious,1,Damaging,"30,66","14,65"
"low freq, many artifacts",UPN2_061,21,36259246,A,T,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu82Gln/c.245T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|4|T),2498,26,2578,"0,0100853375",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,8",Deleterious,"0,036",Damaging,"30,72","33,19"
"low bq, low freq, many artifacts",UPN2_044,21,36259249,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val81Gly/c.242T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),6675,81,6802,"0,0119082623",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,"0,02",Damaging,"29,62","27,16"
"low bq, many samples",UPN2_060,21,36259249,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val81Gly/c.242T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),703,21,728,"0,0288461538",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,"0,02",Damaging,"27,34","14,62"
"low bq, many samples",UPN2_061,21,36259249,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val81Gly/c.242T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),2491,75,2578,"0,0290923196",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,"0,02",Damaging,"27,58",15
"low bq, many samples",UPN2_062,21,36259249,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val81Gly/c.242T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1539,56,1604,"0,0349127182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,"0,02",Damaging,"27,34","14,79"
"low bq, many samples",UPN2_064,21,36259249,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val81Gly/c.242T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),686,20,708,"0,0282485876",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,"0,02",Damaging,"27,84","14,9"
"low bq, many samples",UPN2_065,21,36259249,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val81Gly/c.242T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1262,39,1307,"0,0298393267",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,"0,02",Damaging,"27,78","14,67"
"low bq, many samples",UPN2_071,21,36259249,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val81Gly/c.242T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1670,42,1715,"0,0244897959",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,"0,02",Damaging,"27,43",14
"low bq, many samples",UPN2_072,21,36259249,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val81Gly/c.242T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1826,58,1896,"0,0305907173",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,"0,02",Damaging,"27,55",14
"low bq, many samples",UPN2_075,21,36259249,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val81Gly/c.242T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1650,42,1694,"0,0247933884",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,"0,02",Damaging,"27,85","15,26"
"low bq, many samples",UPN2_076,21,36259249,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val81Gly/c.242T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),865,35,903,"0,0387596899",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,"0,02",Damaging,"27,26","14,2"
"low bq, many samples",UPN2_077,21,36259249,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val81Gly/c.242T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1228,31,1265,"0,0245059289",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,"0,02",Damaging,"27,38","15,65"
"low bq, many samples",UPN2_078,21,36259249,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val81Gly/c.242T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),980,30,1011,"0,0296735905",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,"0,02",Damaging,"27,42","14,43"
"low bq, bad alignment, many samples",UPN2_080,21,36259249,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val81Gly/c.242T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1797,53,1859,"0,0285099516",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,"0,02",Damaging,"26,98","16,15"
"low bq, many samples",UPN2_081,21,36259249,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val81Gly/c.242T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),2506,89,2605,"0,0341650672",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,"0,02",Damaging,"27,76","14,45"
"low bq, many samples",UPN2_083,21,36259249,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val81Gly/c.242T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1527,53,1591,"0,0333123821",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,"0,02",Damaging,"27,43","14,96"
"low bq, many samples",UPN2_084,21,36259249,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val81Gly/c.242T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1397,53,1456,"0,0364010989",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,"0,02",Damaging,"27,38","14,25"
low bq,UPN2_085,21,36259249,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val81Gly/c.242T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),704,22,730,"0,0301369863",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,43",Deleterious,"0,02",Damaging,"27,93","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_089,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),7984,140,8154,"0,0171694874",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"27,74","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_042,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),32298,330,32893,"0,0100325297",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"27,62","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_045,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),30250,334,30910,"0,0108055645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"27,48","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_047,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),33947,365,34662,"0,0105302637",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"27,57","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_049,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),13785,147,14035,"0,0104738155",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"27,57","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_055,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),26621,274,27136,"0,0100972877",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"27,55","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_090,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),9871,168,10117,"0,0166057132",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"28,03","14,08"
"low bq, bad alignment, many samples",UPN2_059,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),400,27,428,"0,0630841121",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"26,13","15,93"
"low bq, bad alignment, many samples",UPN2_060,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),668,55,728,"0,0755494505",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"26,87","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_091,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),8133,123,8296,"0,0148264224",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"27,98","14,11"
"low bq, low freq, many artifacts, many samples",UPN2_092,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),3348,56,3432,"0,0163170163",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"27,82","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_093,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),3218,45,3272,"0,0137530562",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"28,36","14,6"
"low bq, bad alignment, many samples",UPN2_061,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),2367,177,2575,"0,0687378641",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"26,31","14,77"
"low bq, bad alignment, many samples",UPN2_062,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1446,148,1602,"0,0923845194",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"26,64","14,87"
"low bq, bad alignment, many samples",UPN2_063,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),577,52,634,"0,0820189274",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"26,43","14,98"
"low bq, bad alignment, many samples",UPN2_064,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),647,56,707,"0,0792079208",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"26,45","14,36"
"low bq, bad alignment, many samples",UPN2_065,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1207,93,1307,"0,0711553175",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"26,63","14,71"
"low bq, bad alignment, many samples",UPN2_066,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),249,22,272,"0,0808823529",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"26,67","15,73"
"low bq, bad alignment, many samples",UPN2_068,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),567,52,619,"0,084006462",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"26,42","14,35"
"low bq, many samples",UPN2_069,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),539,49,589,"0,0831918506",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"27,03","15,78"
"low bq, bad alignment, many samples",UPN2_070,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),334,26,360,"0,0722222222",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"26,22","15,5"
"low bq, bad alignment, many samples",UPN2_071,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1589,112,1713,"0,0653823701",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"26,36","14,71"
"low bq, bad alignment, many samples",UPN2_072,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1726,161,1897,"0,0848708487",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"26,41","14,49"
"low bq, bad alignment, many samples",UPN2_073,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),512,49,565,"0,0867256637",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"26,26","15,35"
"low bq, bad alignment, many samples",UPN2_075,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1544,133,1693,"0,0785587714",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"26,73","14,84"
"low bq, bad alignment, many samples",UPN2_076,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),816,81,902,"0,0898004435",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"26,55","15,33"
"low bq, bad alignment, many samples",UPN2_077,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1167,95,1265,"0,0750988142",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"26,42","15,06"
"low bq, bad alignment, many samples",UPN2_078,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),923,86,1011,"0,0850642928",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"26,17","14,9"
"low bq, many samples",UPN2_079,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),433,40,476,"0,0840336134",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"27,3","14,95"
"low bq, bad alignment, many samples",UPN2_081,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),2395,192,2604,"0,0737327189",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"26,57","14,52"
"low bq, bad alignment, many samples",UPN2_082,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),640,46,695,"0,0661870504",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"26,72","14,59"
"low bq, bad alignment, many samples",UPN2_083,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1461,126,1591,"0,0791954745",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"26,54","14,87"
"low bq, bad alignment, many samples",UPN2_084,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1321,129,1455,"0,0886597938",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"26,2","14,78"
"low bq, bad alignment, many samples",UPN2_085,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),666,59,730,"0,0808219178",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"26,24","14,54"
"low bq, bad alignment, many samples",UPN2_087,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),564,32,598,"0,0535117057",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"26,73","14,81"
"low bq, bad alignment, many samples",UPN2_088,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),399,30,430,"0,0697674419",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"26,35","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_094,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),8295,138,8468,"0,0162966462",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"27,9","14,05"
"low bq, low freq, many artifacts, many samples",UPN2_095,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),7272,136,7443,"0,0182722021",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"27,97","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_096,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),7883,135,8063,"0,0167431477",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"28,02","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_097,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),11074,194,11349,"0,0170940171",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"27,97","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_098,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),9135,151,9337,"0,0161722181",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"27,86","14,52"
"low bq, low freq, many artifacts, many samples",UPN2_099,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),3984,59,4076,"0,0144749755",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"27,87","14,31"
"low bq, low freq, many artifacts, many samples",UPN2_100,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),5596,78,5697,"0,0136914165",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"28,07","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_101,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),7213,126,7393,"0,0170431489",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"27,73","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_102,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),7132,114,7294,"0,0156292843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"27,98","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_103,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),6141,100,6262,"0,0159693389",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"27,97","14,07"
"low bq, low freq, many artifacts, many samples",UPN2_104,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),6797,124,6925,"0,0179061372",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"27,93","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_105,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),6473,86,6572,"0,0130858186",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"27,84","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_106,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),16272,267,16606,"0,0160785258",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"28,04","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_107,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),13625,224,13910,"0,0161035226",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"28,01","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_108,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),12306,192,12543,"0,0153073427",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"28,22","14,27"
"low bq, low freq, many artifacts, many samples",UPN2_109,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),10210,192,10473,"0,0183328559",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"27,82","14,73"
"low bq, low freq, many artifacts, many samples",UPN2_110,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),12552,194,12807,"0,015147966",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"27,91","14,68"
"low bq, low freq, many artifacts",UPN2_111,21,36259255,A,C,missense_variant(MODERATE|MISSENSE|gTg/gGg|p.Val79Gly/c.236T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),8906,179,9136,"0,0195928196",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,19",Deleterious,156,Tolerated,"27,8","14,08"
"low bq, low freq, many artifacts, many samples",UPN2_061,21,36259258,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met78Arg/c.233T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),2514,53,2577,"0,0205665503",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,1,Damaging,"29,33","14,75"
"low bq, many samples",UPN2_062,21,36259258,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met78Arg/c.233T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1546,47,1599,"0,0293933709",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,1,Damaging,"29,16","14,57"
"low bq, many samples",UPN2_065,21,36259258,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met78Arg/c.233T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1268,35,1307,"0,0267788829",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,1,Damaging,"29,7","15,66"
"low bq, low freq, many artifacts, many samples",UPN2_071,21,36259258,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met78Arg/c.233T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1657,34,1711,"0,0198714202",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,1,Damaging,"28,95","15,44"
"low bq, many samples",UPN2_072,21,36259258,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met78Arg/c.233T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1832,53,1896,"0,0279535865",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,1,Damaging,"28,99","15,49"
"low bq, many samples",UPN2_075,21,36259258,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met78Arg/c.233T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1639,42,1691,"0,0248373743",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,1,Damaging,"29,26","15,1"
"low bq, many samples",UPN2_077,21,36259258,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met78Arg/c.233T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1232,32,1265,"0,0252964427",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,1,Damaging,"29,11","16,03"
"low bq, many samples",UPN2_078,21,36259258,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met78Arg/c.233T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),969,33,1010,"0,0326732673",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,1,Damaging,"28,91","15,73"
"low bq, many samples",UPN2_081,21,36259258,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met78Arg/c.233T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),2528,65,2605,"0,0249520154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,1,Damaging,"29,29","14,91"
"low bq, many samples",UPN2_083,21,36259258,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met78Arg/c.233T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1543,43,1591,"0,027027027",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,1,Damaging,"29,26","15,07"
low bq,UPN2_084,21,36259258,A,C,missense_variant(MODERATE|MISSENSE|aTg/aGg|p.Met78Arg/c.233T>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1410,34,1451,"0,0234321158",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,1,Damaging,"28,96","15,32"
"low freq, many artifacts",UPN2_006,21,36259258,A,T,missense_variant(MODERATE|MISSENSE|aTg/aAg|p.Met78Lys/c.233T>A|480|RUNX1|protein_coding|CODING|ENST00000437180|4|T),3110,33,3167,"0,0104199558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,06",Deleterious,48,Damaging,"31,03","30,82"
"low freq, many artifacts",UPN2_075,21,36259259,T,C,missense_variant(MODERATE|MISSENSE|Atg/Gtg|p.Met78Val/c.232A>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1669,22,1691,"0,0130100532",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,"0,219",Tolerated,"33,27","33,55"
"low bq, low freq, many artifacts, many samples",UPN2_044,21,36259267,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp75Ala/c.224A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),3329,42,3383,"0,0124150163",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,09",Deleterious,31,Damaging,"27,97","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_053,21,36259267,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp75Ala/c.224A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),11113,122,11290,"0,010806023",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,09",Deleterious,31,Damaging,"27,71","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_090,21,36259267,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp75Ala/c.224A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),4980,57,5049,"0,0112893642",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,09",Deleterious,31,Damaging,"27,62","14,12"
"low bq, low freq, many artifacts, many samples",UPN2_092,21,36259267,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp75Ala/c.224A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1676,24,1712,"0,0140186916",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,09",Deleterious,31,Damaging,"27,66","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_093,21,36259267,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp75Ala/c.224A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1610,24,1638,"0,0146520147",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,09",Deleterious,31,Damaging,"28,01","14,92"
"low bq, bad alignment, many samples",UPN2_061,21,36259267,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp75Ala/c.224A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1236,45,1287,"0,034965035",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,09",Deleterious,31,Damaging,"24,4","14,31"
"low bq, bad alignment, many samples",UPN2_062,21,36259267,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp75Ala/c.224A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),777,24,803,"0,0298879203",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,09",Deleterious,31,Damaging,"24,68",14
"low bq, bad alignment, many samples",UPN2_065,21,36259267,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp75Ala/c.224A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),616,28,649,"0,0431432974",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,09",Deleterious,31,Damaging,"25,44","14,25"
"low bq, bad alignment, many samples",UPN2_071,21,36259267,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp75Ala/c.224A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),823,28,853,"0,0328253224",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,09",Deleterious,31,Damaging,"24,58",14
"low bq, bad alignment, many samples",UPN2_072,21,36259267,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp75Ala/c.224A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),909,28,940,"0,029787234",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,09",Deleterious,31,Damaging,"24,77",15
"low bq, bad alignment, many samples",UPN2_075,21,36259267,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp75Ala/c.224A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),817,20,842,"0,0237529691",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,09",Deleterious,31,Damaging,"25,23","14,35"
"low bq, bad alignment, many samples",UPN2_076,21,36259267,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp75Ala/c.224A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),429,20,453,"0,0441501104",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,09",Deleterious,31,Damaging,"24,85",14
"low bq, bad alignment, many samples",UPN2_080,21,36259267,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp75Ala/c.224A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),896,29,928,"0,03125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,09",Deleterious,31,Damaging,"24,83",14
"low bq, bad alignment, many samples",UPN2_081,21,36259267,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp75Ala/c.224A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1263,32,1298,"0,0246533128",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,09",Deleterious,31,Damaging,"24,47",15
"low bq, bad alignment, many samples",UPN2_083,21,36259267,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp75Ala/c.224A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),766,26,795,"0,0327044025",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,09",Deleterious,31,Damaging,"24,75","14,27"
"low bq, bad alignment, many samples",UPN2_084,21,36259267,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp75Ala/c.224A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),698,25,727,"0,0343878955",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,09",Deleterious,31,Damaging,"24,98","16,16"
"low bq, low freq, many artifacts, many samples",UPN2_094,21,36259267,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp75Ala/c.224A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),4173,45,4229,"0,0106408134",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,09",Deleterious,31,Damaging,"27,53","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_095,21,36259267,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp75Ala/c.224A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),3666,45,3717,"0,0121065375",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,09",Deleterious,31,Damaging,"27,64","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_096,21,36259267,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp75Ala/c.224A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),3966,44,4024,"0,0109343936",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,09",Deleterious,31,Damaging,"27,24","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_098,21,36259267,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp75Ala/c.224A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),4599,51,4670,"0,0109207709",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,09",Deleterious,31,Damaging,"27,28","14,71"
"low bq, low freq, many artifacts, many samples",UPN2_099,21,36259267,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp75Ala/c.224A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1992,30,2033,"0,0147565175",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,09",Deleterious,31,Damaging,"27,53","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_101,21,36259267,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp75Ala/c.224A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),3630,50,3691,"0,0135464644",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,09",Deleterious,31,Damaging,"27,23","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_102,21,36259267,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp75Ala/c.224A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),3587,38,3637,"0,0104481716",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,09",Deleterious,31,Damaging,"27,23","17,03"
"low bq, low freq, many artifacts, many samples",UPN2_103,21,36259267,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp75Ala/c.224A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),3076,38,3126,"0,01215611",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,09",Deleterious,31,Damaging,"27,3","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_104,21,36259267,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp75Ala/c.224A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),3413,37,3452,"0,0107184241",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,09",Deleterious,31,Damaging,"27,51","15,51"
"low bq, low freq, many artifacts, many samples",UPN2_105,21,36259267,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp75Ala/c.224A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),3223,49,3280,"0,0149390244",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,09",Deleterious,31,Damaging,"27,35",14
"low bq, low freq, many artifacts, many samples",UPN2_109,21,36259267,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp75Ala/c.224A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),5159,53,5229,"0,0101357812",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,09",Deleterious,31,Damaging,"27,57","14,13"
"low bq, low freq, many artifacts, many samples",UPN2_110,21,36259267,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp75Ala/c.224A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),6309,70,6395,"0,0109460516",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,09",Deleterious,31,Damaging,"27,6","14,19"
"low bq, low freq, many artifacts",UPN2_111,21,36259267,T,G,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp75Ala/c.224A>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),4493,61,4564,"0,0133654689",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,09",Deleterious,31,Damaging,"27,51","14,11"
"low freq, neutral effect",UPN2_006,21,36259271,C,T,missense_variant(MODERATE|MISSENSE|Ggc/Agc|p.Gly74Ser/c.220G>A|480|RUNX1|protein_coding|CODING|ENST00000437180|4|T),1530,44,1575,"0,0279365079",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,"0,383",Tolerated,"35,21","33,86"
"low freq, many artifacts, many samples",UPN2_001,21,36259316,C,G,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly59Arg/c.175G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),2677,36,2717,"0,013249908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,37",Deleterious,29,Damaging,"34,59","30,58"
"low freq, many artifacts, many samples",UPN2_018,21,36259316,C,G,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly59Arg/c.175G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),4726,49,4786,"0,0102381947",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,37",Deleterious,29,Damaging,"34,85","31,51"
"low freq, many artifacts, many samples",UPN2_002,21,36259316,C,G,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly59Arg/c.175G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),3163,44,3208,"0,0137157107",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,37",Deleterious,29,Damaging,"34,88",32
"low freq, many artifacts",UPN2_027,21,36259316,C,G,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly59Arg/c.175G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),6639,83,6734,"0,0123255123",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,37",Deleterious,"0,029",Damaging,"34,93","30,47"
"low freq, many artifacts, many samples",UPN2_035,21,36259316,C,G,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly59Arg/c.175G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),4209,56,4269,"0,0131178262",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,37",Deleterious,29,Damaging,"34,77","30,32"
"low freq, many artifacts, many samples",UPN2_006,21,36259316,C,G,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly59Arg/c.175G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1719,26,1747,"0,014882656",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,37",Deleterious,29,Damaging,"35,03","31,31"
"low freq, many artifacts, many samples",UPN2_007,21,36259316,C,G,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly59Arg/c.175G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),7559,88,7657,"0,0114927517",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,37",Deleterious,29,Damaging,"34,74","30,35"
"low freq, many artifacts, many samples",UPN2_010,21,36259316,C,G,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly59Arg/c.175G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),5715,69,5790,"0,0119170984",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,37",Deleterious,29,Damaging,"34,78","31,06"
"low freq, many artifacts, many samples",UPN2_011,21,36259316,C,G,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly59Arg/c.175G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),7032,86,7146,"0,0120347047",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,37",Deleterious,29,Damaging,"34,77","30,56"
"low freq, many artifacts, many samples",UPN2_012,21,36259316,C,G,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly59Arg/c.175G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),3746,45,3799,"0,0118452224",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,37",Deleterious,29,Damaging,"34,59","30,56"
"low freq, many artifacts, many samples",UPN2_061,21,36259316,C,G,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly59Arg/c.175G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1453,25,1482,"0,0168690958",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,37",Deleterious,29,Damaging,"34,57","29,12"
many samples,UPN2_077,21,36259316,C,G,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly59Arg/c.175G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),799,24,823,"0,0291616039",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,37",Deleterious,29,Damaging,"34,08","31,25"
"low freq, many artifacts, many samples",UPN2_081,21,36259316,C,G,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly59Arg/c.175G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),1449,20,1474,"0,013568521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,37",Deleterious,29,Damaging,"34,8","29,1"
"inspected, strandbias",UPN2_083,21,36259316,C,G,missense_variant(MODERATE|MISSENSE|Ggc/Cgc|p.Gly59Arg/c.175G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),956,25,981,"0,0254841998",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,37",Deleterious,29,Damaging,"34,51","29,84"
"leakage, freq too low for SNP",UPN2_094,21,36259324,A,G,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu56Ser/c.167T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),4717,178,4905,"0,0362895005",0,0,0,0,1,1,0,0,2,"1,4623","0,0169",COSM24756,haematopoietic_and_lymphoid_tissue,7,NO,rs111527738,NO,"0,015",NO,YES,"-0,8",Neutral,"0,65",Tolerated,"35,63","35,42"
"leakage, freq too low for SNP",UPN2_105,21,36259324,A,G,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu56Ser/c.167T>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),3866,45,3922,"0,0114737379",0,0,0,0,1,0,0,1,2,"1,4623","0,0169",COSM24756,haematopoietic_and_lymphoid_tissue,7,NO,rs111527738,NO,"0,015",NO,YES,"-0,8",Neutral,"0,65",Tolerated,"35,59","35,58"
"inspected, strandbias",UPN2_083,21,36259344,T,TG,frameshift_variant(HIGH||cca/ccCa|p.Gly50fs/c.146dupC|480|RUNX1|protein_coding|CODING|ENST00000437180|4|TG),974,42,981,"0,0428134557",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,19",NA
"low freq, many artifacts, many samples",UPN2_016,21,36259344,TG,T,frameshift_variant(HIGH||cca/|p.Pro49fs/c.146delC|480|RUNX1|protein_coding|CODING|ENST00000437180|4|T),4325,47,4380,"0,0107305936",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,41",NA
"low freq, many artifacts, many samples",UPN2_017,21,36259344,TG,T,frameshift_variant(HIGH||cca/|p.Pro49fs/c.146delC|480|RUNX1|protein_coding|CODING|ENST00000437180|4|T),2879,33,2921,"0,0112975009",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,5",NA
"low freq, many artifacts, many samples",UPN2_018,21,36259344,TG,T,frameshift_variant(HIGH||cca/|p.Pro49fs/c.146delC|480|RUNX1|protein_coding|CODING|ENST00000437180|4|T),4730,53,4794,"0,011055486",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,53",NA
"low freq, many artifacts, many samples",UPN2_021,21,36259344,TG,T,frameshift_variant(HIGH||cca/|p.Pro49fs/c.146delC|480|RUNX1|protein_coding|CODING|ENST00000437180|4|T),4671,49,4735,"0,0103484688",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,44",NA
"low freq, many artifacts, many samples",UPN2_035,21,36259344,TG,T,frameshift_variant(HIGH||cca/|p.Pro49fs/c.146delC|480|RUNX1|protein_coding|CODING|ENST00000437180|4|T),4222,51,4281,"0,0119131044",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,4",NA
"low freq, many artifacts, many samples",UPN2_050,21,36259344,TG,T,frameshift_variant(HIGH||cca/|p.Pro49fs/c.146delC|480|RUNX1|protein_coding|CODING|ENST00000437180|4|T),9608,108,9749,"0,0110780593",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,22",NA
"low freq, many artifacts, many samples",UPN2_052,21,36259344,TG,T,frameshift_variant(HIGH||cca/|p.Pro49fs/c.146delC|480|RUNX1|protein_coding|CODING|ENST00000437180|4|T),9209,110,9345,"0,0117710005",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,21",NA
"low freq, many artifacts, many samples",UPN2_039,21,36259344,TG,T,frameshift_variant(HIGH||cca/|p.Pro49fs/c.146delC|480|RUNX1|protein_coding|CODING|ENST00000437180|4|T),5049,67,5131,"0,0130578835",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,48",NA
"low freq, many artifacts, many samples",UPN2_008,21,36259344,TG,T,frameshift_variant(HIGH||cca/|p.Pro49fs/c.146delC|480|RUNX1|protein_coding|CODING|ENST00000437180|4|T),14089,148,14278,"0,0103655974",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,35",NA
"low freq, many artifacts, many samples",UPN2_055,21,36259344,TG,T,frameshift_variant(HIGH||cca/|p.Pro49fs/c.146delC|480|RUNX1|protein_coding|CODING|ENST00000437180|4|T),14348,164,14560,"0,0112637363",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,23",NA
"low freq, many artifacts, many samples",UPN2_056,21,36259344,TG,T,frameshift_variant(HIGH||cca/|p.Pro49fs/c.146delC|480|RUNX1|protein_coding|CODING|ENST00000437180|4|T),5094,59,5166,"0,0114208285",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,32",NA
"low freq, many artifacts, many samples",UPN2_040,21,36259344,TG,T,frameshift_variant(HIGH||cca/|p.Pro49fs/c.146delC|480|RUNX1|protein_coding|CODING|ENST00000437180|4|T),2013,26,2042,"0,0127326151",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,51",NA
many samples,UPN2_093,21,36259344,TG,T,frameshift_variant(HIGH||cca/|p.Pro49fs/c.146delC|480|RUNX1|protein_coding|CODING|ENST00000437180|4|T),1837,43,1881,"0,0228601808",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,54",NA
"low freq, many artifacts, many samples",UPN2_095,21,36259344,TG,T,frameshift_variant(HIGH||cca/|p.Pro49fs/c.146delC|480|RUNX1|protein_coding|CODING|ENST00000437180|4|T),4185,43,4244,"0,010131951",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,41",NA
"low freq, many artifacts",UPN2_098,21,36259344,TG,T,frameshift_variant(HIGH||cca/|p.Pro49fs/c.146delC|480|RUNX1|protein_coding|CODING|ENST00000437180|4|T),5292,69,5369,"0,0128515552",0,0,0,1,0,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,32",NA
many samples,UPN2_001,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),2616,84,2710,"0,03099631",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,24","31,57"
many samples,UPN2_014,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),6108,151,6262,"0,0241137017",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,22","31,47"
"low freq, many artifacts, many samples",UPN2_015,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),9588,160,9772,"0,0163733115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,18","31,46"
many samples,UPN2_016,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),4254,97,4359,"0,0222528103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,17","31,29"
many samples,UPN2_017,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),2830,69,2907,"0,0237358101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,14","31,84"
"low freq, many artifacts, many samples",UPN2_018,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),4664,101,4769,"0,0211784441",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,27","31,71"
many samples,UPN2_019,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),4870,111,4991,"0,0222400321",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,17","31,7"
many samples,UPN2_020,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),4230,125,4361,"0,0286631507",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,18","31,77"
many samples,UPN2_021,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),4555,151,4716,"0,0320186599",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,16","31,93"
many samples,UPN2_002,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),3103,97,3208,"0,0302369077",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,14","31,4"
many samples,UPN2_003,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),715,21,737,"0,0284938942",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,29","31,14"
"low freq, many artifacts, many samples",UPN2_022,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),5844,113,5968,"0,0189343164",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,2","31,65"
"low freq, many artifacts, many samples",UPN2_023,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),6711,147,6876,"0,0213787086",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,19","31,48"
"low freq, many artifacts, many samples",UPN2_024,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),3127,39,3168,"0,0123106061",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,21","31,44"
"low freq, many artifacts, many samples",UPN2_025,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),8479,152,8641,"0,0175905566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,22","31,19"
many samples,UPN2_026,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),7858,186,8057,"0,0230855157",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,13","31,4"
many samples,UPN2_004,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),844,27,873,"0,0309278351",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,24","31,59"
many samples,UPN2_027,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),6522,173,6714,"0,0257670539",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,22","31,87"
many samples,UPN2_028,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),4491,108,4609,"0,0234324148",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,14","31,5"
"low freq, many artifacts, many samples",UPN2_044,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),3596,47,3649,"0,0128802412",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"31,98",31
many samples,UPN2_029,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),5647,152,5810,"0,02616179",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,22","31,45"
"low freq, many artifacts, many samples",UPN2_030,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),7648,155,7818,"0,0198260425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,18","31,93"
"low freq, many artifacts, many samples",UPN2_031,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),5143,93,5242,"0,0177413201",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,16","31,81"
many samples,UPN2_005,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),989,35,1026,"0,0341130604",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,17",32
"low freq, many artifacts, many samples",UPN2_032,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1696,28,1730,"0,0161849711",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,19",32
"low freq, many artifacts, many samples",UPN2_046,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),10651,155,10830,"0,014312096",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,02","31,81"
"low freq, many artifacts, many samples",UPN2_033,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),4881,101,4998,"0,0202080832",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,16","31,36"
"low freq, many artifacts, many samples",UPN2_034,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1489,26,1520,"0,0171052632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,26","31,31"
"low freq, many artifacts, many samples",UPN2_047,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),17952,208,18195,"0,011431712",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"31,91","31,24"
"low freq, many artifacts, many samples",UPN2_048,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),17091,302,17412,"0,0173443602",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"31,81","31,56"
many samples,UPN2_035,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),4138,107,4257,"0,0251350716",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,17","31,39"
many samples,UPN2_036,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),3575,103,3686,"0,0279435703",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,16","31,83"
many samples,UPN2_006,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1654,83,1739,"0,0477285796",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,12","31,43"
"low freq, many artifacts, many samples",UPN2_049,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),7220,82,7323,"0,0111975966",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"31,89","31,15"
"low freq, many artifacts, many samples",UPN2_037,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),10615,212,10849,"0,0195409715",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,16","31,42"
"inspected, strandbias",UPN2_038,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),11907,317,12250,"0,025877551",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,"0,001",Damaging,"32,12","31,6"
many samples,UPN2_039,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),4975,128,5108,"0,0250587314",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,17","31,23"
"low freq, many artifacts, many samples",UPN2_053,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),12141,138,12312,"0,011208577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,01","31,18"
many samples,UPN2_007,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),7380,226,7618,"0,0296665792",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,2","31,6"
"inspected, strandbias",UPN2_008,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),13790,369,14214,"0,0259603208",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,"0,001",Damaging,"32,1","31,72"
"low freq, many artifacts, many samples",UPN2_009,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),11306,236,11565,"0,0204063986",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,09","31,63"
many samples,UPN2_010,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),5629,128,5772,"0,0221760222",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,22","31,56"
many samples,UPN2_011,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),6807,200,7015,"0,028510335",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,14","31,45"
"low freq, many artifacts, many samples",UPN2_056,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),5074,58,5140,"0,0112840467",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"31,97","31,19"
"low freq, many artifacts, many samples",UPN2_057,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),7067,106,7187,"0,0147488521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"31,98","31,79"
"low freq, many artifacts, many samples",UPN2_058,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),5772,102,5887,"0,0173263122",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,05","30,9"
"inspected, strandbias",UPN2_012,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),3675,108,3792,"0,0284810127",0,0,0,0,1,1,0,0,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,"0,001",Damaging,"32,15","31,94"
many samples,UPN2_040,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1977,55,2035,"0,027027027",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,14","31,47"
many samples,UPN2_013,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),2128,64,2196,"0,029143898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,14",32
many samples,UPN2_061,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1426,48,1480,"0,0324324324",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,14","31,4"
many samples,UPN2_062,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),916,28,948,"0,029535865",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,13","31,21"
many samples,UPN2_071,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),966,30,998,"0,0300601202",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,16","31,03"
many samples,UPN2_072,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1024,38,1064,"0,0357142857",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,1","31,29"
many samples,UPN2_075,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),937,34,975,"0,0348717949",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,13","30,62"
many samples,UPN2_080,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1066,38,1107,"0,0343270099",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,29","31,53"
many samples,UPN2_081,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),1421,49,1473,"0,0332654447",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,15","31,31"
many samples,UPN2_083,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),942,31,973,"0,0318602261",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,31",32
"inspected, strandbias",UPN2_084,21,36259363,G,C,missense_variant(MODERATE|MISSENSE|cCt/cGt|p.Pro43Arg/c.128C>G|480|RUNX1|protein_coding|CODING|ENST00000437180|4|C),823,26,850,"0,0305882353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,78",Deleterious,1,Damaging,"32,23","30,62"
inspected,UPN2_089,21,36259381,C,G,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser37Thr/c.110G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),685,24,710,"0,0338028169",0,0,0,0,0,0,0,1,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,213,Tolerated,"35,11","35,62"
inspected,UPN2_090,21,36259381,C,G,missense_variant(MODERATE|MISSENSE|aGc/aCc|p.Ser37Thr/c.110G>C|480|RUNX1|protein_coding|CODING|ENST00000437180|4|G),461,50,511,"0,0978473581",0,1,0,0,0,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,15",Neutral,"0,213",Tolerated,"35,13","34,8"
"low freq, many artifacts",UPN2_047,21,44514798,A,T,missense_variant(MODERATE|MISSENSE|tTc/tAc|p.Phe150Tyr/c.449T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|6|T),2245,25,2289,"0,0109217999",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,82",Deleterious,0,Damaging,"34,22","35,64"
"low freq, many artifacts",UPN2_044,21,44514816,A,G,missense_variant(MODERATE|MISSENSE|cTg/cCg|p.Leu144Pro/c.431T>C|240|U2AF1|protein_coding|CODING|ENST00000291552|6|G),1560,22,1588,"0,0138539043",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,74",Deleterious,"0,001",Damaging,"34,41","34,41"
"low bq, low freq, many artifacts, many samples",UPN2_070,21,44514844,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe135Val/c.403T>G|240|U2AF1|protein_coding|CODING|ENST00000291552|6|C),9376,98,9501,"0,0103147037",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,56",Deleterious,1,Damaging,"29,39","15,51"
"low bq, low freq, many artifacts, many samples",UPN2_073,21,44514844,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe135Val/c.403T>G|240|U2AF1|protein_coding|CODING|ENST00000291552|6|C),4160,44,4234,"0,0103920642",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,56",Deleterious,1,Damaging,"29,8",16
"low bq, low freq, many artifacts, many samples",UPN2_076,21,44514844,A,C,missense_variant(MODERATE|MISSENSE|Ttt/Gtt|p.Phe135Val/c.403T>G|240|U2AF1|protein_coding|CODING|ENST00000291552|6|C),11363,123,11527,"0,0106705995",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,56",Deleterious,1,Damaging,"29,68","15,15"
"low freq, many artifacts",UPN2_006,21,44514846,C,T,stop_gained(HIGH|NONSENSE|tGg/tAg|p.Trp134*/c.401G>A|240|U2AF1|protein_coding|CODING|ENST00000291552|6|T),1242,31,1277,"0,024275646",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,69","34,74"
"low freq, many artifacts",UPN2_006,21,44514850,G,A,missense_variant(MODERATE|MISSENSE|Cgt/Tgt|p.Arg133Cys/c.397C>T|240|U2AF1|protein_coding|CODING|ENST00000291552|6|A),2450,44,2504,"0,017571885",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,79",Deleterious,0,Damaging,"31,8","34,93"
"low freq, many artifacts",UPN2_044,21,44514867,A,G,missense_variant(MODERATE|MISSENSE|gTg/gCg|p.Val127Ala/c.380T>C|240|U2AF1|protein_coding|CODING|ENST00000291552|6|G),3043,78,3142,"0,0248249523",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,5",Deleterious,"0,141",Tolerated,"32,56","32,47"
"low freq, many artifacts",UPN2_044,21,44514873,T,A,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys125Met/c.374A>T|240|U2AF1|protein_coding|CODING|ENST00000291552|6|A),3072,38,3142,"0,0120942075",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,97",Deleterious,"0,016",Damaging,"31,49","29,42"
"low freq, many artifacts",UPN2_042,21,44514873,T,C,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys125Arg/c.374A>G|240|U2AF1|protein_coding|CODING|ENST00000291552|6|C),6131,65,6233,"0,0104283652",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,67",Neutral,"0,67",Tolerated,"31,59","30,88"
"low freq, many artifacts",UPN2_005,21,44514873,T,C,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys125Arg/c.374A>G|240|U2AF1|protein_coding|CODING|ENST00000291552|6|C),2157,22,2188,"0,0100548446",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,67",Neutral,"0,67",Tolerated,"31,97","33,18"
"low freq, many artifacts",UPN2_046,21,44514873,T,C,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys125Arg/c.374A>G|240|U2AF1|protein_coding|CODING|ENST00000291552|6|C),13175,137,13386,"0,0102345734",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,67",Neutral,"0,67",Tolerated,"31,59","30,86"
"inspected, many artifacts",UPN2_044,21,44514880,C,T,missense_variant(MODERATE|MISSENSE|Gcg/Acg|p.Ala123Thr/c.367G>A|240|U2AF1|protein_coding|CODING|ENST00000291552|6|T),2988,141,3142,"0,0448758752",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,71",Deleterious,"0,01",Damaging,"31,5","32,11"
"low bq, low freq, many artifacts",UPN2_044,21,44514882,T,C,missense_variant(MODERATE|MISSENSE|gAt/gGt|p.Asp122Gly/c.365A>G|240|U2AF1|protein_coding|CODING|ENST00000291552|6|C),3096,39,3142,"0,0124124761",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,42",Deleterious,"0,035",Damaging,"32,62","29,08"
"low bq, low freq, many artifacts, many samples",UPN2_081,21,44514892,G,T,missense_variant(MODERATE|MISSENSE|Cgt/Agt|p.Arg119Ser/c.355C>A|240|U2AF1|protein_coding|CODING|ENST00000291552|6|T),3698,38,3746,"0,0101441538",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,32",Neutral,"0,4",Tolerated,"31,08","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_052,21,44514894,C,A,missense_variant(MODERATE|MISSENSE|cGc/cTc|p.Arg118Leu/c.353G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|6|A),5697,60,5776,"0,0103878116",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-5,21",Deleterious,53,Tolerated,"31,15","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_052,21,44514896,A,T,missense_variant(MODERATE|MISSENSE|ttT/ttA|p.Phe117Leu/c.351T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|6|T),5693,60,5776,"0,0103878116",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,72",Deleterious,2,Damaging,"34,14","25,53"
"low bq, low freq, many artifacts, many samples",UPN2_011,21,44514897,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe117Tyr/c.350T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|6|T),7420,83,7513,"0,0110475176",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,44",Neutral,"0,31",Tolerated,"34,42","22,23"
"low bq, low freq, many artifacts, many samples",UPN2_073,21,44524425,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|caG/caT|p.Gln44His/c.132G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),7426,78,7515,"0,0103792415",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,37,Damaging,"30,69","16,72"
"low bq, low freq, many artifacts",UPN2_082,21,44524425,C,A,missense_variant+splice_region_variant(MODERATE|MISSENSE|caG/caT|p.Gln44His/c.132G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),21489,220,21775,"0,0101033295",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,46",Deleterious,37,Damaging,"30,63","15,85"
"inspected, many artifacts",UPN2_056,21,44524426,TG,T,frameshift_variant+splice_region_variant(HIGH||cag/|p.Gln44fs/c.130delC|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),536,32,575,"0,0556521739",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,53",NA
"low bq, low freq, many artifacts",UPN2_042,21,44524433,A,T,missense_variant(MODERATE|MISSENSE|Ttt/Att|p.Phe42Ile/c.124T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),8348,91,8488,"0,0107210179",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,64",Deleterious,367,Tolerated,"31,46","21,14"
"low freq, many artifacts",UPN2_006,21,44524435,G,T,missense_variant(MODERATE|MISSENSE|aCg/aAg|p.Thr41Lys/c.122C>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),5420,139,5565,"0,0249775382",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,96",Deleterious,"0,007",Damaging,"33,11","30,63"
"low bq, low freq, many artifacts",UPN2_042,21,44524443,A,T,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn38Lys/c.114T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),8382,91,8493,"0,0107147062",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,34",Deleterious,112,Tolerated,"33,2","18,42"
"low bq, low freq, many artifacts, many samples",UPN2_059,21,44524449,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu36Phe/c.108G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),2348,27,2380,"0,0113445378",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,42,Damaging,"29,92","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_063,21,44524449,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu36Phe/c.108G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),12935,131,13098,"0,010001527",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,42,Damaging,"29,89","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_065,21,44524449,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu36Phe/c.108G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),4833,55,4913,"0,0111947893",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,42,Damaging,"29,74","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_067,21,44524449,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu36Phe/c.108G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),31318,321,31736,"0,0101146962",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,42,Damaging,"29,92","14,6"
"low bq, low freq, many artifacts, many samples",UPN2_070,21,44524449,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu36Phe/c.108G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),14537,150,14740,"0,0101763908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,42,Damaging,"29,96","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_073,21,44524449,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu36Phe/c.108G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),7404,78,7494,"0,0104083267",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,42,Damaging,"29,94","14,73"
"low bq, low freq, many artifacts",UPN2_085,21,44524449,C,A,missense_variant(MODERATE|MISSENSE|ttG/ttT|p.Leu36Phe/c.108G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),20852,230,21160,"0,0108695652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,06",Deleterious,42,Damaging,"29,89","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_059,21,44524453,C,A,missense_variant(MODERATE|MISSENSE|cGg/cTg|p.Arg35Leu/c.104G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),2345,28,2376,"0,0117845118",0,0,0,0,1,0,0,0,1,NO,NO,COSM211657,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-6,54",Deleterious,1,Damaging,29,"14,25"
"low bq, low freq, many artifacts, many samples",UPN2_060,21,44524453,C,A,missense_variant(MODERATE|MISSENSE|cGg/cTg|p.Arg35Leu/c.104G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),19218,230,19523,"0,0117809763",0,0,0,0,1,0,0,0,1,NO,NO,COSM211657,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-6,54",Deleterious,1,Damaging,"28,57","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_061,21,44524453,C,A,missense_variant(MODERATE|MISSENSE|cGg/cTg|p.Arg35Leu/c.104G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),20057,245,20416,"0,0120003918",0,0,0,0,1,0,0,0,1,NO,NO,COSM211657,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-6,54",Deleterious,1,Damaging,"28,54","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_062,21,44524453,C,A,missense_variant(MODERATE|MISSENSE|cGg/cTg|p.Arg35Leu/c.104G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),15651,211,15913,"0,0132595991",0,0,0,0,1,0,0,0,1,NO,NO,COSM211657,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-6,54",Deleterious,1,Damaging,"28,79","15,52"
"low bq, low freq, many artifacts, many samples",UPN2_063,21,44524453,C,A,missense_variant(MODERATE|MISSENSE|cGg/cTg|p.Arg35Leu/c.104G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),12851,161,13085,"0,0123041651",0,0,0,0,1,0,0,0,1,NO,NO,COSM211657,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-6,54",Deleterious,1,Damaging,"28,58","15,42"
"low bq, low freq, many artifacts, many samples",UPN2_065,21,44524453,C,A,missense_variant(MODERATE|MISSENSE|cGg/cTg|p.Arg35Leu/c.104G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),4820,62,4910,"0,0126272912",0,0,0,0,1,0,0,0,1,NO,NO,COSM211657,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-6,54",Deleterious,1,Damaging,"28,36","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_066,21,44524453,C,A,missense_variant(MODERATE|MISSENSE|cGg/cTg|p.Arg35Leu/c.104G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),22196,271,22550,"0,0120177384",0,0,0,0,1,0,0,0,1,NO,NO,COSM211657,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-6,54",Deleterious,1,Damaging,"28,64","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_067,21,44524453,C,A,missense_variant(MODERATE|MISSENSE|cGg/cTg|p.Arg35Leu/c.104G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),31172,424,31696,"0,0133770823",0,0,0,0,1,0,0,0,1,NO,NO,COSM211657,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-6,54",Deleterious,1,Damaging,"28,48","15,92"
"low bq, low freq, many artifacts, many samples",UPN2_068,21,44524453,C,A,missense_variant(MODERATE|MISSENSE|cGg/cTg|p.Arg35Leu/c.104G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),22056,252,22393,"0,0112535167",0,0,0,0,1,0,0,0,1,NO,NO,COSM211657,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-6,54",Deleterious,1,Damaging,"28,76","15,62"
"low bq, low freq, many artifacts, many samples",UPN2_069,21,44524453,C,A,missense_variant(MODERATE|MISSENSE|cGg/cTg|p.Arg35Leu/c.104G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),32922,408,33428,"0,0122053368",0,0,0,0,1,0,0,0,1,NO,NO,COSM211657,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-6,54",Deleterious,1,Damaging,"28,73","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_070,21,44524453,C,A,missense_variant(MODERATE|MISSENSE|cGg/cTg|p.Arg35Leu/c.104G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),14512,165,14725,"0,0112054329",0,0,0,0,1,0,0,0,1,NO,NO,COSM211657,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-6,54",Deleterious,1,Damaging,"28,73","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_071,21,44524453,C,A,missense_variant(MODERATE|MISSENSE|cGg/cTg|p.Arg35Leu/c.104G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),13127,143,13327,"0,0107300968",0,0,0,0,1,0,0,0,1,NO,NO,COSM211657,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-6,54",Deleterious,1,Damaging,"28,63","16,07"
"low bq, low freq, many artifacts, many samples",UPN2_072,21,44524453,C,A,missense_variant(MODERATE|MISSENSE|cGg/cTg|p.Arg35Leu/c.104G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),9963,124,10163,"0,0122011217",0,0,0,0,1,0,0,0,1,NO,NO,COSM211657,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-6,54",Deleterious,1,Damaging,"28,65","15,65"
"low bq, low freq, many artifacts, many samples",UPN2_073,21,44524453,C,A,missense_variant(MODERATE|MISSENSE|cGg/cTg|p.Arg35Leu/c.104G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),7331,102,7479,"0,0136381869",0,0,0,0,1,0,0,0,1,NO,NO,COSM211657,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-6,54",Deleterious,1,Damaging,"28,53","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_074,21,44524453,C,A,missense_variant(MODERATE|MISSENSE|cGg/cTg|p.Arg35Leu/c.104G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),9739,122,9888,"0,0123381877",0,0,0,0,1,0,0,0,1,NO,NO,COSM211657,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-6,54",Deleterious,1,Damaging,"28,62","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_075,21,44524453,C,A,missense_variant(MODERATE|MISSENSE|cGg/cTg|p.Arg35Leu/c.104G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),30077,394,30610,"0,0128716106",0,0,0,0,1,0,0,0,1,NO,NO,COSM211657,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-6,54",Deleterious,1,Damaging,"28,49","15,54"
"low bq, low freq, many artifacts, many samples",UPN2_076,21,44524453,C,A,missense_variant(MODERATE|MISSENSE|cGg/cTg|p.Arg35Leu/c.104G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),24844,294,25227,"0,01165418",0,0,0,0,1,0,0,0,1,NO,NO,COSM211657,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-6,54",Deleterious,1,Damaging,"28,8","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_077,21,44524453,C,A,missense_variant(MODERATE|MISSENSE|cGg/cTg|p.Arg35Leu/c.104G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),24961,296,25342,"0,0116802147",0,0,0,0,1,0,0,0,1,NO,NO,COSM211657,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-6,54",Deleterious,1,Damaging,"28,7","15,6"
"low bq, low freq, many artifacts, many samples",UPN2_078,21,44524453,C,A,missense_variant(MODERATE|MISSENSE|cGg/cTg|p.Arg35Leu/c.104G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),21856,264,22173,"0,0119063726",0,0,0,0,1,0,0,0,1,NO,NO,COSM211657,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-6,54",Deleterious,1,Damaging,"28,89","15,59"
"low bq, low freq, many artifacts, many samples",UPN2_079,21,44524453,C,A,missense_variant(MODERATE|MISSENSE|cGg/cTg|p.Arg35Leu/c.104G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),16291,205,16564,"0,0123762376",0,0,0,0,1,0,0,0,1,NO,NO,COSM211657,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-6,54",Deleterious,1,Damaging,"28,63","14,85"
"low bq, low freq, many artifacts, many samples",UPN2_080,21,44524453,C,A,missense_variant(MODERATE|MISSENSE|cGg/cTg|p.Arg35Leu/c.104G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),12423,161,12605,"0,0127727092",0,0,0,0,1,0,0,0,1,NO,NO,COSM211657,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-6,54",Deleterious,1,Damaging,"28,57","17,19"
"low bq, low freq, many artifacts, many samples",UPN2_081,21,44524453,C,A,missense_variant(MODERATE|MISSENSE|cGg/cTg|p.Arg35Leu/c.104G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),3873,41,3922,"0,0104538501",0,0,0,0,1,0,0,0,1,NO,NO,COSM211657,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-6,54",Deleterious,1,Damaging,"28,47","16,27"
"low bq, low freq, many artifacts, many samples",UPN2_082,21,44524453,C,A,missense_variant(MODERATE|MISSENSE|cGg/cTg|p.Arg35Leu/c.104G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),21336,268,21694,"0,0123536462",0,0,0,0,1,0,0,0,1,NO,NO,COSM211657,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-6,54",Deleterious,1,Damaging,"28,27","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_083,21,44524453,C,A,missense_variant(MODERATE|MISSENSE|cGg/cTg|p.Arg35Leu/c.104G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),31146,369,31631,"0,0116657709",0,0,0,0,1,0,0,0,1,NO,NO,COSM211657,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-6,54",Deleterious,1,Damaging,"28,69","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_084,21,44524453,C,A,missense_variant(MODERATE|MISSENSE|cGg/cTg|p.Arg35Leu/c.104G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),25225,319,25623,"0,0124497522",0,0,0,0,1,0,0,0,1,NO,NO,COSM211657,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-6,54",Deleterious,1,Damaging,"28,7","15,68"
"low bq, low freq, many artifacts, many samples",UPN2_085,21,44524453,C,A,missense_variant(MODERATE|MISSENSE|cGg/cTg|p.Arg35Leu/c.104G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),20776,286,21126,"0,0135378207",0,0,0,0,1,0,0,0,1,NO,NO,COSM211657,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-6,54",Deleterious,1,Damaging,"28,52","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_086,21,44524453,C,A,missense_variant(MODERATE|MISSENSE|cGg/cTg|p.Arg35Leu/c.104G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),15577,203,15843,"0,0128132298",0,0,0,0,1,0,0,0,1,NO,NO,COSM211657,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-6,54",Deleterious,1,Damaging,"28,73","16,12"
"low bq, low freq, many artifacts, many samples",UPN2_087,21,44524453,C,A,missense_variant(MODERATE|MISSENSE|cGg/cTg|p.Arg35Leu/c.104G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),32485,404,33036,"0,0122290834",0,0,0,0,1,0,0,0,1,NO,NO,COSM211657,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-6,54",Deleterious,1,Damaging,"28,58","15,44"
"low bq, low freq, many artifacts",UPN2_088,21,44524453,C,A,missense_variant(MODERATE|MISSENSE|cGg/cTg|p.Arg35Leu/c.104G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),23399,329,23803,"0,0138217872",0,0,0,0,1,0,0,0,1,NO,NO,COSM211657,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-6,54",Deleterious,1,Damaging,"28,45","15,3"
"Hotspot, inspected, low freq, many artifacts",UPN2_087,21,44524456,G,A,missense_variant(MODERATE|MISSENSE|tCt/tTt|p.Ser34Phe/c.101C>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),31578,1242,32993,"0,0376443488",0,0,0,0,1,1,0,1,3,0,NO,"COSM1142948, COSM166866","cervix, endometrium, haematopoietic_and_lymphoid_tissue, liver, lung, pancreas, stomach, urinary_tract","4, 6, 71, 8, 26, 20, 2, 6",NO,rs371769427,NO,NA,NO,NO,"-5,64",Deleterious,0,Damaging,"31,33","32,81"
"low freq, many artifacts",UPN2_006,21,44524457,A,G,missense_variant(MODERATE|MISSENSE|Tct/Cct|p.Ser34Pro/c.100T>C|240|U2AF1|protein_coding|CODING|ENST00000291552|2|G),5489,61,5563,"0,0109653065",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,7",Deleterious,0,Damaging,"33,87","33,9"
"low bq, low freq, many artifacts, many samples",UPN2_042,21,44524459,C,A,missense_variant(MODERATE|MISSENSE|tGc/tTc|p.Cys33Phe/c.98G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),8323,109,8443,"0,012910103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,15",Deleterious,1,Damaging,"31,48","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_043,21,44524459,C,A,missense_variant(MODERATE|MISSENSE|tGc/tTc|p.Cys33Phe/c.98G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),17384,286,17711,"0,0161481565",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,15",Deleterious,1,Damaging,"31,4","15,48"
"low bq, low freq, many artifacts, many samples",UPN2_044,21,44524459,C,A,missense_variant(MODERATE|MISSENSE|tGc/tTc|p.Cys33Phe/c.98G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),5965,95,6087,"0,0156070314",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,15",Deleterious,1,Damaging,"31,54","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_045,21,44524459,C,A,missense_variant(MODERATE|MISSENSE|tGc/tTc|p.Cys33Phe/c.98G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),20168,295,20529,"0,0143699157",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,15",Deleterious,1,Damaging,"31,46","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_046,21,44524459,C,A,missense_variant(MODERATE|MISSENSE|tGc/tTc|p.Cys33Phe/c.98G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),25700,355,26138,"0,0135817584",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,15",Deleterious,1,Damaging,"31,52","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_047,21,44524459,C,A,missense_variant(MODERATE|MISSENSE|tGc/tTc|p.Cys33Phe/c.98G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),6727,106,6845,"0,015485756",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,15",Deleterious,1,Damaging,"31,51","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_006,21,44524459,C,A,missense_variant(MODERATE|MISSENSE|tGc/tTc|p.Cys33Phe/c.98G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),5462,59,5531,"0,0106671488",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,15",Deleterious,1,Damaging,"33,19","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_049,21,44524459,C,A,missense_variant(MODERATE|MISSENSE|tGc/tTc|p.Cys33Phe/c.98G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),4609,54,4680,"0,0115384615",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,15",Deleterious,1,Damaging,"31,15","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_050,21,44524459,C,A,missense_variant(MODERATE|MISSENSE|tGc/tTc|p.Cys33Phe/c.98G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),20903,300,21315,"0,0140745954",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,15",Deleterious,1,Damaging,"31,49","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_051,21,44524459,C,A,missense_variant(MODERATE|MISSENSE|tGc/tTc|p.Cys33Phe/c.98G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),27861,403,28341,"0,0142196817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,15",Deleterious,1,Damaging,"31,49","15,42"
"low bq, low freq, many artifacts, many samples",UPN2_052,21,44524459,C,A,missense_variant(MODERATE|MISSENSE|tGc/tTc|p.Cys33Phe/c.98G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),24465,343,24882,"0,0137850655",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,15",Deleterious,1,Damaging,"31,47","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_053,21,44524459,C,A,missense_variant(MODERATE|MISSENSE|tGc/tTc|p.Cys33Phe/c.98G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),33476,482,34067,"0,0141485895",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,15",Deleterious,1,Damaging,"31,54","15,24"
"low bq, low freq, many artifacts, many samples",UPN2_054,21,44524459,C,A,missense_variant(MODERATE|MISSENSE|tGc/tTc|p.Cys33Phe/c.98G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),22360,297,22759,"0,0130497825",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,15",Deleterious,1,Damaging,"31,56","15,46"
"low bq, low freq, many artifacts, many samples",UPN2_055,21,44524459,C,A,missense_variant(MODERATE|MISSENSE|tGc/tTc|p.Cys33Phe/c.98G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),24879,379,25386,"0,0149294887",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,15",Deleterious,1,Damaging,"31,52","15,49"
"low bq, low freq, many artifacts, many samples",UPN2_057,21,44524459,C,A,missense_variant(MODERATE|MISSENSE|tGc/tTc|p.Cys33Phe/c.98G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),24393,308,24775,"0,012431887",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,15",Deleterious,1,Damaging,"31,47","15,81"
"low bq, low freq, many artifacts, many samples",UPN2_058,21,44524459,C,A,missense_variant(MODERATE|MISSENSE|tGc/tTc|p.Cys33Phe/c.98G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),30109,431,30633,"0,014069794",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,15",Deleterious,1,Damaging,"31,43","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_060,21,44524459,C,A,missense_variant(MODERATE|MISSENSE|tGc/tTc|p.Cys33Phe/c.98G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),19116,214,19396,"0,0110332027",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,15",Deleterious,1,Damaging,"31,29","16,08"
"low bq, low freq, many artifacts, many samples",UPN2_061,21,44524459,C,A,missense_variant(MODERATE|MISSENSE|tGc/tTc|p.Cys33Phe/c.98G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),19920,216,20219,"0,0106830209",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,15",Deleterious,1,Damaging,"31,21","16,46"
"low bq, low freq, many artifacts, many samples",UPN2_062,21,44524459,C,A,missense_variant(MODERATE|MISSENSE|tGc/tTc|p.Cys33Phe/c.98G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),15598,159,15792,"0,0100683891",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,15",Deleterious,1,Damaging,"31,41","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_063,21,44524459,C,A,missense_variant(MODERATE|MISSENSE|tGc/tTc|p.Cys33Phe/c.98G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),12816,135,12995,"0,010388611",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,15",Deleterious,1,Damaging,"31,3","15,55"
"low bq, low freq, many artifacts, many samples",UPN2_064,21,44524459,C,A,missense_variant(MODERATE|MISSENSE|tGc/tTc|p.Cys33Phe/c.98G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),2034,31,2069,"0,0149830836",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,15",Deleterious,1,Damaging,"31,41","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_065,21,44524459,C,A,missense_variant(MODERATE|MISSENSE|tGc/tTc|p.Cys33Phe/c.98G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),4766,59,4854,"0,0121549238",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,15",Deleterious,1,Damaging,"31,26","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_066,21,44524459,C,A,missense_variant(MODERATE|MISSENSE|tGc/tTc|p.Cys33Phe/c.98G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),22068,243,22374,"0,0108608206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,15",Deleterious,1,Damaging,"31,31","15,91"
"low bq, low freq, many artifacts, many samples",UPN2_067,21,44524459,C,A,missense_variant(MODERATE|MISSENSE|tGc/tTc|p.Cys33Phe/c.98G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),31000,367,31465,"0,0116637534",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,15",Deleterious,1,Damaging,"31,24","15,68"
"low bq, low freq, many artifacts, many samples",UPN2_068,21,44524459,C,A,missense_variant(MODERATE|MISSENSE|tGc/tTc|p.Cys33Phe/c.98G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),21917,224,22194,"0,0100928179",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,15",Deleterious,1,Damaging,"31,42","16,06"
"low bq, low freq, many artifacts, many samples",UPN2_069,21,44524459,C,A,missense_variant(MODERATE|MISSENSE|tGc/tTc|p.Cys33Phe/c.98G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),32752,333,33169,"0,0100394947",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,15",Deleterious,1,Damaging,"31,24","15,46"
"low bq, low freq, many artifacts, many samples",UPN2_070,21,44524459,C,A,missense_variant(MODERATE|MISSENSE|tGc/tTc|p.Cys33Phe/c.98G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),14437,152,14621,"0,0103960057",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,15",Deleterious,1,Damaging,"31,33","14,99"
"low bq, low freq, many artifacts, many samples",UPN2_071,21,44524459,C,A,missense_variant(MODERATE|MISSENSE|tGc/tTc|p.Cys33Phe/c.98G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),13050,148,13219,"0,0111960057",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,15",Deleterious,1,Damaging,"31,4","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_072,21,44524459,C,A,missense_variant(MODERATE|MISSENSE|tGc/tTc|p.Cys33Phe/c.98G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),9964,102,10084,"0,0101150337",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,15",Deleterious,1,Damaging,"31,3","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_075,21,44524459,C,A,missense_variant(MODERATE|MISSENSE|tGc/tTc|p.Cys33Phe/c.98G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),29964,337,30363,"0,011099035",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,15",Deleterious,1,Damaging,"31,28","15,78"
"low bq, low freq, many artifacts, many samples",UPN2_077,21,44524459,C,A,missense_variant(MODERATE|MISSENSE|tGc/tTc|p.Cys33Phe/c.98G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),24813,254,25146,"0,0101010101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,15",Deleterious,1,Damaging,"31,32","16,06"
"low bq, low freq, many artifacts, many samples",UPN2_080,21,44524459,C,A,missense_variant(MODERATE|MISSENSE|tGc/tTc|p.Cys33Phe/c.98G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),12336,144,12519,"0,0115025162",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,15",Deleterious,1,Damaging,"31,34","15,42"
"low bq, low freq, many artifacts, many samples",UPN2_082,21,44524459,C,A,missense_variant(MODERATE|MISSENSE|tGc/tTc|p.Cys33Phe/c.98G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),21309,241,21604,"0,0111553416",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,15",Deleterious,1,Damaging,"30,13","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_083,21,44524459,C,A,missense_variant(MODERATE|MISSENSE|tGc/tTc|p.Cys33Phe/c.98G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),30956,332,31367,"0,0105843721",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,15",Deleterious,1,Damaging,"31,36","15,44"
"low bq, low freq, many artifacts, many samples",UPN2_084,21,44524459,C,A,missense_variant(MODERATE|MISSENSE|tGc/tTc|p.Cys33Phe/c.98G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),25038,294,25406,"0,0115720696",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,15",Deleterious,1,Damaging,"31,32","15,64"
"low bq, low freq, many artifacts, many samples",UPN2_086,21,44524459,C,A,missense_variant(MODERATE|MISSENSE|tGc/tTc|p.Cys33Phe/c.98G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),15515,162,15732,"0,0102974828",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,15",Deleterious,1,Damaging,"31,41","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_087,21,44524459,C,A,missense_variant(MODERATE|MISSENSE|tGc/tTc|p.Cys33Phe/c.98G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),32326,351,32774,"0,0107097089",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,15",Deleterious,1,Damaging,"31,33","15,55"
"low bq, low freq, many artifacts",UPN2_088,21,44524459,C,A,missense_variant(MODERATE|MISSENSE|tGc/tTc|p.Cys33Phe/c.98G>T|240|U2AF1|protein_coding|CODING|ENST00000291552|2|A),23322,260,23650,"0,0109936575",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-10,15",Deleterious,1,Damaging,"31,24","15,53"
"low bq, low freq, many artifacts, many samples",UPN2_081,21,44524460,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys33Gly/c.97T>G|240|U2AF1|protein_coding|CODING|ENST00000291552|2|C),2030,21,2063,"0,0101793505",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-11,14",Deleterious,2,Damaging,"33,83","18,43"
"low bq, many samples",UPN2_082,21,44524460,A,C,missense_variant(MODERATE|MISSENSE|Tgc/Ggc|p.Cys33Gly/c.97T>G|240|U2AF1|protein_coding|CODING|ENST00000291552|2|C),16305,428,16838,"0,0254186958",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-11,14",Deleterious,2,Damaging,"29,93","16,25"
"inspected, strandbias",UPN2_056,21,44524460,A,G,missense_variant(MODERATE|MISSENSE|Tgc/Cgc|p.Cys33Arg/c.97T>C|240|U2AF1|protein_coding|CODING|ENST00000291552|2|G),286,21,310,"0,0677419355",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-11,12",Deleterious,"0,001",Damaging,"32,56","30,05"
"low bq, low freq, many artifacts, many samples",UPN2_044,21,44524460,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys33Ser/c.97T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),3182,37,3232,"0,0114480198",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,26",Deleterious,0,Damaging,"33,31","15,19"
"low freq, many artifacts",UPN2_006,21,44524460,A,T,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys33Ser/c.97T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),2899,36,2941,"0,0122407344",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,26",Deleterious,0,Damaging,"33,83","27,69"
"low bq, low freq, many artifacts, many samples",UPN2_043,21,44524470,A,T,missense_variant(MODERATE|MISSENSE|caT/caA|p.His29Gln/c.87T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),8732,96,8859,"0,0108364375",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,35",Deleterious,0,Damaging,"33,82","17,74"
"low bq, low freq, many artifacts, many samples",UPN2_005,21,44524470,A,T,missense_variant(MODERATE|MISSENSE|caT/caA|p.His29Gln/c.87T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),2769,30,2805,"0,0106951872",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,35",Deleterious,0,Damaging,"34,25","17,67"
"low bq, low freq, many artifacts, many samples",UPN2_046,21,44524470,A,T,missense_variant(MODERATE|MISSENSE|caT/caA|p.His29Gln/c.87T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),12891,146,13084,"0,0111586671",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,35",Deleterious,0,Damaging,"33,76","19,21"
"low bq, low freq, many artifacts, many samples",UPN2_047,21,44524470,A,T,missense_variant(MODERATE|MISSENSE|caT/caA|p.His29Gln/c.87T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),3380,35,3428,"0,010210035",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,35",Deleterious,0,Damaging,"33,84","17,54"
"low bq, low freq, many artifacts, many samples",UPN2_006,21,44524470,A,T,missense_variant(MODERATE|MISSENSE|caT/caA|p.His29Gln/c.87T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),2733,29,2768,"0,0104768786",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,35",Deleterious,0,Damaging,"34,23","23,72"
"low bq, low freq, many artifacts, many samples",UPN2_050,21,44524470,A,T,missense_variant(MODERATE|MISSENSE|caT/caA|p.His29Gln/c.87T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),10520,119,10682,"0,0111402359",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,35",Deleterious,0,Damaging,"33,73","18,63"
"low bq, low freq, many artifacts, many samples",UPN2_052,21,44524470,A,T,missense_variant(MODERATE|MISSENSE|caT/caA|p.His29Gln/c.87T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),12258,149,12456,"0,0119621066",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,35",Deleterious,0,Damaging,"33,67","16,83"
"low bq, low freq, many artifacts, many samples",UPN2_053,21,44524470,A,T,missense_variant(MODERATE|MISSENSE|caT/caA|p.His29Gln/c.87T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),16811,183,17046,"0,0107356565",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,35",Deleterious,0,Damaging,"33,83","18,96"
"low bq, low freq, many artifacts",UPN2_058,21,44524470,A,T,missense_variant(MODERATE|MISSENSE|caT/caA|p.His29Gln/c.87T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),15121,158,15330,"0,0103065884",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,35",Deleterious,0,Damaging,"33,85","18,61"
"low freq, many artifacts",UPN2_081,21,44524471,T,C,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His29Arg/c.86A>G|240|U2AF1|protein_coding|CODING|ENST00000291552|2|C),1921,20,1944,"0,0102880658",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,38",Deleterious,"0,001",Damaging,"34,97","33,4"
"low freq, many artifacts",UPN2_081,21,44524474,C,T,missense_variant(MODERATE|MISSENSE|cGt/cAt|p.Arg28His/c.83G>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),1911,25,1946,"0,0128468654",0,0,0,0,1,0,0,1,2,NO,NO,"COSM4101858, COSM4101857",stomach,2,NO,NO,NO,NO,NO,NO,"-4,22",Deleterious,"0,014",Damaging,"33,85","34,8"
"low bq, low freq, many artifacts",UPN2_046,21,44524476,A,T,stop_gained(HIGH|NONSENSE|tgT/tgA|p.Cys27*/c.81T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),12914,135,13089,"0,0103140041",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,52","22,07"
"low bq, low freq, many artifacts, many samples",UPN2_042,21,44524478,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys27Ser/c.79T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),4165,43,4224,"0,0101799242",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,26",Deleterious,1,Damaging,"33,99","17,81"
"low bq, low freq, many artifacts, many samples",UPN2_049,21,44524478,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys27Ser/c.79T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),2301,25,2343,"0,0106700811",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,26",Deleterious,1,Damaging,"34,1","17,64"
"low bq, low freq, many artifacts, many samples",UPN2_058,21,44524478,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys27Ser/c.79T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),15098,167,15334,"0,0108908308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,26",Deleterious,1,Damaging,"34,05","19,92"
"low bq, low freq, many artifacts, many samples",UPN2_003,21,44524491,G,T,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe22Leu/c.66C>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),1786,24,1814,"0,01323043",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,26",Deleterious,179,Tolerated,"33,2",14
"low bq, low freq, many artifacts, many samples",UPN2_004,21,44524491,G,T,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe22Leu/c.66C>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),2211,26,2241,"0,0116019634",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,26",Deleterious,179,Tolerated,"33,38",14
"low bq, low freq, many artifacts, many samples",UPN2_043,21,44524491,G,T,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe22Leu/c.66C>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),8766,93,8868,"0,0104871448",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,26",Deleterious,179,Tolerated,"32,69","14,19"
"low bq, low freq, many artifacts, many samples",UPN2_045,21,44524491,G,T,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe22Leu/c.66C>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),10151,112,10289,"0,0108854116",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,26",Deleterious,179,Tolerated,"32,79","14,36"
"low bq, low freq, many artifacts, many samples",UPN2_047,21,44524491,G,T,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe22Leu/c.66C>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),3377,49,3429,"0,0142898804",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,26",Deleterious,179,Tolerated,"32,77","15,76"
"low bq, low freq, many artifacts, many samples",UPN2_006,21,44524491,G,T,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe22Leu/c.66C>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),2732,34,2769,"0,012278801",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,26",Deleterious,179,Tolerated,"33,29",14
"low bq, low freq, many artifacts, many samples",UPN2_050,21,44524491,G,T,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe22Leu/c.66C>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),10568,118,10693,"0,0110352567",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,26",Deleterious,179,Tolerated,"32,71","16,08"
"low bq, low freq, many artifacts, many samples",UPN2_007,21,44524491,G,T,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe22Leu/c.66C>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),21542,228,21794,"0,0104615949",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,26",Deleterious,179,Tolerated,"33,45","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_011,21,44524491,G,T,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe22Leu/c.66C>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),19722,204,19953,"0,0102240265",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,26",Deleterious,179,Tolerated,"33,37","14,45"
"low bq, low freq, many artifacts",UPN2_055,21,44524491,G,T,missense_variant(MODERATE|MISSENSE|ttC/ttA|p.Phe22Leu/c.66C>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),12573,138,12731,"0,0108396827",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,26",Deleterious,179,Tolerated,"32,73","15,88"
"low bq, low freq, many artifacts",UPN2_042,21,44524492,A,T,missense_variant(MODERATE|MISSENSE|tTc/tAc|p.Phe22Tyr/c.65T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),4161,43,4224,"0,0101799242",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,98",Neutral,308,Tolerated,"34,47","24,12"
"low bq, low freq, many artifacts",UPN2_043,21,44524494,A,T,stop_gained(HIGH|NONSENSE|taT/taA|p.Tyr21*/c.63T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),8742,90,8868,"0,0101488498",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,77","16,16"
"low freq, many artifacts",UPN2_049,21,44524495,TA,T,frameshift_variant(HIGH||tat/|p.Tyr21fs/c.61delT|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),2306,25,2347,"0,010651896",0,0,0,0,0,0,0,1,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,46",NA
"low freq, many artifacts",UPN2_047,21,44524498,A,G,missense_variant(MODERATE|MISSENSE|tTt/tCt|p.Phe20Ser/c.59T>C|240|U2AF1|protein_coding|CODING|ENST00000291552|2|G),3362,36,3429,"0,0104986877",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,45",Deleterious,0,Damaging,"34,17",34
"low bq, low freq, many artifacts",UPN2_050,21,44524498,A,T,missense_variant(MODERATE|MISSENSE|tTt/tAt|p.Phe20Tyr/c.59T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),10541,111,10694,"0,0103796521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,8",Deleterious,0,Damaging,"34,01","16,77"
"low bq, low freq, many artifacts, many samples",UPN2_006,21,44524501,G,T,stop_gained(HIGH|NONSENSE|tCa/tAa|p.Ser19*/c.56C>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),2729,32,2769,"0,0115565186",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,58",14
"low bq, low freq, many artifacts, many samples",UPN2_055,21,44524501,G,T,stop_gained(HIGH|NONSENSE|tCa/tAa|p.Ser19*/c.56C>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),12557,137,12735,"0,0107577542",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,28","15,41"
"low bq, low freq, many artifacts, many samples",UPN2_002,21,44524505,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys18Ser/c.52T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),9101,107,9236,"0,0115851018",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,16",Deleterious,0,Damaging,"33,44","17,43"
"low bq, low freq, many artifacts, many samples",UPN2_023,21,44524505,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys18Ser/c.52T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),10861,130,11037,"0,011778563",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,16",Deleterious,0,Damaging,"33,93","17,01"
"low bq, low freq, many artifacts, many samples",UPN2_024,21,44524505,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys18Ser/c.52T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),4588,50,4655,"0,0107411386",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,16",Deleterious,0,Damaging,"33,96","20,44"
"low bq, low freq, many artifacts, many samples",UPN2_004,21,44524505,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys18Ser/c.52T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),2208,25,2242,"0,0111507583",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,16",Deleterious,0,Damaging,"33,39","17,52"
"low bq, low freq, many artifacts, many samples",UPN2_042,21,44524505,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys18Ser/c.52T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),4154,60,4225,"0,0142011834",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,16",Deleterious,0,Damaging,"33,61","19,8"
"low bq, low freq, many artifacts, many samples",UPN2_043,21,44524505,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys18Ser/c.52T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),8709,117,8871,"0,0131890429",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,16",Deleterious,0,Damaging,"33,41","17,05"
"low bq, low freq, many artifacts, many samples",UPN2_044,21,44524505,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys18Ser/c.52T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),3020,38,3071,"0,0123738196",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,16",Deleterious,0,Damaging,"33,47","18,63"
"low bq, low freq, many artifacts, many samples",UPN2_029,21,44524505,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys18Ser/c.52T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),10970,119,11133,"0,0106889428",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,16",Deleterious,0,Damaging,"33,94","20,08"
"low bq, low freq, many artifacts, many samples",UPN2_005,21,44524505,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys18Ser/c.52T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),2771,33,2810,"0,0117437722",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,16",Deleterious,0,Damaging,"33,51","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_045,21,44524505,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys18Ser/c.52T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),10133,116,10293,"0,011269795",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,16",Deleterious,0,Damaging,"33,47","17,97"
"low bq, low freq, many artifacts, many samples",UPN2_047,21,44524505,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys18Ser/c.52T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),3371,48,3429,"0,0139982502",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,16",Deleterious,0,Damaging,"33,56","16,77"
"low bq, low freq, many artifacts, many samples",UPN2_006,21,44524505,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys18Ser/c.52T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),2730,31,2769,"0,0111953774",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,16",Deleterious,0,Damaging,"33,52","16,58"
"low bq, low freq, many artifacts, many samples",UPN2_049,21,44524505,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys18Ser/c.52T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),2305,34,2347,"0,0144865786",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,16",Deleterious,0,Damaging,"33,4","16,59"
"low bq, low freq, many artifacts, many samples",UPN2_050,21,44524505,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys18Ser/c.52T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),10501,129,10698,"0,0120583287",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,16",Deleterious,0,Damaging,"33,37","17,88"
"low bq, low freq, many artifacts, many samples",UPN2_051,21,44524505,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys18Ser/c.52T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),13985,167,14233,"0,0117332959",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,16",Deleterious,0,Damaging,"33,52","17,81"
"low bq, low freq, many artifacts, many samples",UPN2_052,21,44524505,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys18Ser/c.52T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),12277,139,12465,"0,0111512234",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,16",Deleterious,0,Damaging,"33,4","17,04"
"low bq, low freq, many artifacts, many samples",UPN2_054,21,44524505,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys18Ser/c.52T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),11230,115,11413,"0,0100762289",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,16",Deleterious,0,Damaging,"33,41","16,89"
"low bq, low freq, many artifacts, many samples",UPN2_008,21,44524505,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys18Ser/c.52T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),23895,262,24223,"0,0108161665",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,16",Deleterious,0,Damaging,"33,58","17,75"
"low bq, low freq, many artifacts, many samples",UPN2_010,21,44524505,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys18Ser/c.52T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),17188,186,17431,"0,0106706443",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,16",Deleterious,0,Damaging,"33,56","16,97"
"low bq, low freq, many artifacts, many samples",UPN2_011,21,44524505,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys18Ser/c.52T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),19628,235,19957,"0,0117753169",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,16",Deleterious,0,Damaging,"33,55","16,56"
"low bq, low freq, many artifacts, many samples",UPN2_055,21,44524505,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys18Ser/c.52T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),12526,158,12736,"0,0124057789",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,16",Deleterious,0,Damaging,"33,46","18,73"
"low bq, low freq, many artifacts, many samples",UPN2_057,21,44524505,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys18Ser/c.52T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),12252,131,12450,"0,0105220884",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,16",Deleterious,0,Damaging,"33,57","18,47"
"low bq, low freq, many artifacts, many samples",UPN2_058,21,44524505,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys18Ser/c.52T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),15146,170,15359,"0,0110684289",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,16",Deleterious,0,Damaging,"33,55","17,93"
"low bq, low freq, many artifacts, many samples",UPN2_012,21,44524505,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys18Ser/c.52T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),8802,108,8930,"0,0120940649",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,16",Deleterious,0,Damaging,"33,58","17,44"
"low bq, low freq, many artifacts, many samples",UPN2_040,21,44524505,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys18Ser/c.52T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),7317,82,7430,"0,0110363392",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,16",Deleterious,0,Damaging,"33,88","19,21"
"low bq, low freq, many artifacts",UPN2_013,21,44524505,A,T,missense_variant(MODERATE|MISSENSE|Tgt/Agt|p.Cys18Ser/c.52T>A|240|U2AF1|protein_coding|CODING|ENST00000291552|2|T),5770,64,5857,"0,0109270958",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,16",Deleterious,0,Damaging,"33,5","16,38"
"low freq, many artifacts",UPN2_044,X,15808636,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys6Asn/c.18G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|1|T),2561,53,2621,"0,0202212896",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,"0,257",Tolerated,"35,64","35,43"
"low bq, low freq, many artifacts",UPN2_071,X,15808640,A,C,missense_variant(MODERATE|MISSENSE|Acg/Ccg|p.Thr8Pro/c.22A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|1|C),2172,28,2211,"0,012663953",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,11",Neutral,275,Tolerated,"31,6","15,14"
"low freq, many artifacts",UPN2_056,X,15808650,A,G,missense_variant(MODERATE|MISSENSE|gAg/gGg|p.Glu11Gly/c.32A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|1|G),2844,29,2881,"0,0100659493",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,63",Neutral,"0,07",Tolerated,"34,89","33,28"
"low freq, many artifacts",UPN2_044,X,15808651,G,T,missense_variant(MODERATE|MISSENSE|gaG/gaT|p.Glu11Asp/c.33G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|1|T),2563,40,2621,"0,0152613506",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,84",Neutral,"0,152",Tolerated,"35,32","35,8"
"low bq, bad alignment, many samples",UPN2_061,X,15808654,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys12Asn/c.36A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|1|C),1067,34,1108,"0,0306859206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,46,Damaging,"25,06","14,74"
"low bq, bad alignment, many samples",UPN2_062,X,15808654,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys12Asn/c.36A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|1|C),879,39,928,"0,0420258621",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,46,Damaging,"25,35","14,9"
"low bq, bad alignment, many samples",UPN2_068,X,15808654,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys12Asn/c.36A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|1|C),564,20,589,"0,0339558574",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,46,Damaging,"25,2","14,9"
"low bq, bad alignment, many samples",UPN2_071,X,15808654,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys12Asn/c.36A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|1|C),2132,70,2210,"0,0316742081",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,46,Damaging,"25,32","15,74"
"low bq, bad alignment, many samples",UPN2_072,X,15808654,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys12Asn/c.36A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|1|C),1656,42,1720,"0,0244186047",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,46,Damaging,"25,82","14,64"
"low bq, bad alignment, many samples",UPN2_075,X,15808654,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys12Asn/c.36A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|1|C),1156,30,1195,"0,0251046025",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,46,Damaging,"26,41","14,23"
"low bq, bad alignment, many samples",UPN2_079,X,15808654,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys12Asn/c.36A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|1|C),920,23,948,"0,0242616034",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,46,Damaging,"25,43","14,3"
"low bq, bad alignment, many samples",UPN2_080,X,15808654,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys12Asn/c.36A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|1|C),1088,33,1124,"0,0293594306",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,46,Damaging,"24,92","15,15"
"low bq, bad alignment",UPN2_081,X,15808654,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys12Asn/c.36A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|1|C),1959,59,2026,"0,0291214215",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,46,Damaging,"25,49","14,86"
"low freq, many artifacts",UPN2_036,X,15809085,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys24Glu/c.70A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|G),1179,20,1200,"0,0166666667",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,28",Neutral,"0,004",Damaging,"35,07","35,55"
"low bq, low freq, many artifacts",UPN2_010,X,15809104,G,C,missense_variant(MODERATE|MISSENSE|cGt/cCt|p.Arg30Pro/c.89G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|C),1993,21,2014,"0,0104270109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,2",Neutral,"0,07",Tolerated,"32,3","25,67"
"low bq, low freq, many artifacts, many samples",UPN2_022,X,15809116,T,A,missense_variant(MODERATE|MISSENSE|cTt/cAt|p.Leu34His/c.101T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|A),2095,30,2131,"0,0140778977",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,43",Deleterious,1,Damaging,29,"17,07"
"low bq, low freq, many artifacts, many samples",UPN2_025,X,15809116,T,A,missense_variant(MODERATE|MISSENSE|cTt/cAt|p.Leu34His/c.101T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|A),2246,33,2290,"0,0144104803",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,43",Deleterious,1,Damaging,"28,8","16,67"
"low bq, low freq, many artifacts, many samples",UPN2_026,X,15809116,T,A,missense_variant(MODERATE|MISSENSE|cTt/cAt|p.Leu34His/c.101T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|A),2077,26,2107,"0,0123398196",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,43",Deleterious,1,Damaging,"28,84","17,92"
"low bq, low freq, many artifacts, many samples",UPN2_046,X,15809116,T,A,missense_variant(MODERATE|MISSENSE|cTt/cAt|p.Leu34His/c.101T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|A),1026,20,1054,"0,0189753321",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,43",Deleterious,1,Damaging,"29,1","22,2"
"low bq, low freq, many artifacts, many samples",UPN2_035,X,15809116,T,A,missense_variant(MODERATE|MISSENSE|cTt/cAt|p.Leu34His/c.101T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|A),2226,41,2283,"0,0179588261",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,43",Deleterious,1,Damaging,"28,55","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_037,X,15809116,T,A,missense_variant(MODERATE|MISSENSE|cTt/cAt|p.Leu34His/c.101T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|A),2481,31,2527,"0,0122675109",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,43",Deleterious,1,Damaging,"28,85","16,58"
"low bq, low freq, many artifacts, many samples",UPN2_052,X,15809116,T,A,missense_variant(MODERATE|MISSENSE|cTt/cAt|p.Leu34His/c.101T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|A),1412,23,1446,"0,0159059474",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,43",Deleterious,1,Damaging,"29,25","17,65"
"low bq, low freq, many artifacts, many samples",UPN2_038,X,15809116,T,A,missense_variant(MODERATE|MISSENSE|cTt/cAt|p.Leu34His/c.101T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|A),1564,20,1586,"0,0126103405",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,43",Deleterious,1,Damaging,"28,75",14
"low bq, low freq, many artifacts, many samples",UPN2_039,X,15809116,T,A,missense_variant(MODERATE|MISSENSE|cTt/cAt|p.Leu34His/c.101T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|A),1455,22,1481,"0,0148548278",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,43",Deleterious,1,Damaging,"28,53","16,82"
"low bq, low freq, many artifacts, many samples",UPN2_053,X,15809116,T,A,missense_variant(MODERATE|MISSENSE|cTt/cAt|p.Leu34His/c.101T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|A),2284,33,2330,"0,0141630901",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,43",Deleterious,1,Damaging,"29,41","19,21"
"low bq, low freq, many artifacts, many samples",UPN2_008,X,15809116,T,A,missense_variant(MODERATE|MISSENSE|cTt/cAt|p.Leu34His/c.101T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|A),1967,21,1992,"0,0105421687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,43",Deleterious,1,Damaging,"29,93",14
"low bq, low freq, many artifacts",UPN2_055,X,15809116,T,A,missense_variant(MODERATE|MISSENSE|cTt/cAt|p.Leu34His/c.101T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|A),1519,21,1544,"0,0136010363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,43",Deleterious,1,Damaging,"28,87",14
"low freq, many artifacts",UPN2_011,X,15809119,C,T,missense_variant(MODERATE|MISSENSE|gCt/gTt|p.Ala35Val/c.104C>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|T),1278,24,1308,"0,0183486239",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,87",Deleterious,0,Damaging,"33,08","29,92"
"low bq, low freq, many artifacts, many samples",UPN2_025,X,15809125,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu37Gln/c.110T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|A),2257,26,2290,"0,0113537118",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,72,Tolerated,"30,78","15,69"
"low bq, low freq, many artifacts, many samples",UPN2_053,X,15809125,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu37Gln/c.110T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|A),2291,26,2330,"0,0111587983",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,72,Tolerated,"31,15","21,65"
"low bq, low freq, many artifacts, many samples",UPN2_009,X,15809125,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu37Gln/c.110T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|A),2917,40,2961,"0,0135089497",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,72,Tolerated,"31,5","15,45"
"low bq, low freq, many artifacts, many samples",UPN2_010,X,15809125,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu37Gln/c.110T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|A),1983,25,2013,"0,0124192747",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,72,Tolerated,"31,65","17,52"
"low bq, low freq, many artifacts",UPN2_055,X,15809125,T,A,missense_variant(MODERATE|MISSENSE|cTg/cAg|p.Leu37Gln/c.110T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|A),1516,23,1544,"0,0148963731",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,49",Neutral,72,Tolerated,"31,15","19,39"
"low bq, bad alignment, many samples",UPN2_061,X,15809131,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp39Ala/c.116A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|C),646,21,680,"0,0308823529",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,27,Damaging,"26,68","14,86"
"low bq, bad alignment, many samples",UPN2_065,X,15809131,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp39Ala/c.116A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|C),670,29,712,"0,0407303371",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,27,Damaging,"26,53","15,14"
"low bq, bad alignment, many samples",UPN2_068,X,15809131,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp39Ala/c.116A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|C),744,20,774,"0,0258397933",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,27,Damaging,"26,72","14,35"
"low bq, bad alignment, many samples",UPN2_082,X,15809131,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp39Ala/c.116A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|C),545,24,578,"0,0415224913",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,27,Damaging,"25,91","15,08"
"low bq, low freq, many artifacts",UPN2_088,X,15809131,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp39Ala/c.116A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|C),1004,20,1035,"0,0193236715",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,39",Deleterious,27,Damaging,"27,2","15,25"
"low bq, low freq, many artifacts, many samples",UPN2_014,X,15809131,A,T,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp39Val/c.116A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|T),1571,23,1607,"0,0143123833",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,49",Deleterious,2,Damaging,"28,88","18,78"
"low bq, low freq, many artifacts, many samples",UPN2_022,X,15809131,A,T,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp39Val/c.116A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|T),4121,49,4197,"0,011675006",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,49",Deleterious,2,Damaging,"28,86","16,27"
"low bq, low freq, many artifacts, many samples",UPN2_025,X,15809131,A,T,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp39Val/c.116A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|T),4423,49,4503,"0,0108816345",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,49",Deleterious,2,Damaging,"28,95","16,33"
"low bq, low freq, many artifacts, many samples",UPN2_042,X,15809131,A,T,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp39Val/c.116A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|T),1369,29,1415,"0,0204946996",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,49",Deleterious,2,Damaging,"28,29","15,45"
"low bq, low freq, many artifacts, many samples",UPN2_043,X,15809131,A,T,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp39Val/c.116A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|T),1872,32,1922,"0,0166493236",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,49",Deleterious,2,Damaging,"28,46","15,03"
"low bq, low freq, many artifacts, many samples",UPN2_029,X,15809131,A,T,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp39Val/c.116A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|T),1467,20,1497,"0,0133600534",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,49",Deleterious,2,Damaging,"28,69","17,75"
"low bq, low freq, many artifacts, many samples",UPN2_031,X,15809131,A,T,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp39Val/c.116A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|T),2036,22,2067,"0,0106434446",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,49",Deleterious,2,Damaging,"28,93","15,59"
"low bq, low freq, many artifacts, many samples",UPN2_032,X,15809131,A,T,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp39Val/c.116A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|T),1325,20,1353,"0,014781966",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,49",Deleterious,2,Damaging,"28,36","15,55"
"low bq, low freq, many artifacts, many samples",UPN2_046,X,15809131,A,T,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp39Val/c.116A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|T),2004,40,2060,"0,0194174757",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,49",Deleterious,2,Damaging,"28,56","15,95"
"low bq, low freq, many artifacts, many samples",UPN2_033,X,15809131,A,T,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp39Val/c.116A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|T),1753,23,1786,"0,0128779395",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,49",Deleterious,2,Damaging,"28,55","19,17"
"low bq, low freq, many artifacts, many samples",UPN2_035,X,15809131,A,T,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp39Val/c.116A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|T),4417,58,4506,"0,0128717266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,49",Deleterious,2,Damaging,"28,61","18,84"
"low bq, low freq, many artifacts, many samples",UPN2_036,X,15809131,A,T,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp39Val/c.116A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|T),2298,36,2350,"0,0153191489",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,49",Deleterious,2,Damaging,"28,79","20,44"
"low bq, low freq, many artifacts, many samples",UPN2_006,X,15809131,A,T,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp39Val/c.116A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|T),1925,25,1958,"0,0127681307",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,49",Deleterious,2,Damaging,"29,88","18,72"
"low bq, low freq, many artifacts, many samples",UPN2_037,X,15809131,A,T,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp39Val/c.116A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|T),4901,52,4993,"0,0104145804",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,49",Deleterious,2,Damaging,"28,79","16,65"
"low bq, low freq, many artifacts, many samples",UPN2_051,X,15809131,A,T,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp39Val/c.116A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|T),1973,42,2033,"0,0206591244",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,49",Deleterious,2,Damaging,"28,53","18,6"
"low bq, low freq, many artifacts, many samples",UPN2_052,X,15809131,A,T,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp39Val/c.116A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|T),2766,36,2827,"0,0127343474",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,49",Deleterious,2,Damaging,"28,59","17,64"
"low bq, low freq, many artifacts, many samples",UPN2_053,X,15809131,A,T,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp39Val/c.116A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|T),4446,60,4552,"0,0131810193",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,49",Deleterious,2,Damaging,"28,57","16,15"
"low bq, low freq, many artifacts, many samples",UPN2_054,X,15809131,A,T,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp39Val/c.116A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|T),1598,25,1641,"0,015234613",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,49",Deleterious,2,Damaging,"28,33","15,68"
"low bq, low freq, many artifacts, many samples",UPN2_011,X,15809131,A,T,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp39Val/c.116A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|T),2541,26,2578,"0,0100853375",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,49",Deleterious,2,Damaging,"30,13","16,65"
"low bq, low freq, many artifacts, many samples",UPN2_055,X,15809131,A,T,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp39Val/c.116A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|T),2944,54,3033,"0,0178041543",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,49",Deleterious,2,Damaging,"28,28","17,26"
"low bq, low freq, many artifacts, many samples",UPN2_057,X,15809131,A,T,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp39Val/c.116A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|T),1932,25,1979,"0,0126326427",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,49",Deleterious,2,Damaging,"28,66","17,36"
"low bq, low freq, many artifacts, many samples",UPN2_058,X,15809131,A,T,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp39Val/c.116A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|T),2570,40,2627,"0,0152264941",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,49",Deleterious,2,Damaging,"28,71","15,85"
"low bq, low freq, many artifacts",UPN2_040,X,15809131,A,T,missense_variant(MODERATE|MISSENSE|gAc/gTc|p.Asp39Val/c.116A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|2|T),2349,29,2394,"0,0121136174",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,49",Deleterious,2,Damaging,"28,86","16,52"
"low bq, many samples",UPN2_014,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),7767,1181,9049,"0,1305116587",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,24","14,11"
"low bq, many samples",UPN2_016,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),5102,892,6073,"0,1468796312",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,56","14,26"
"low bq, many samples",UPN2_021,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),5338,942,6339,"0,1486038807",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,54","14,12"
"low bq, many samples",UPN2_002,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),13619,1093,14775,"0,0739763113",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,48","14,23"
"low bq, many samples",UPN2_003,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),2160,109,2277,"0,0478700044",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,08","14,13"
"low bq, many samples",UPN2_022,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),12035,1897,14134,"0,1342153672",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,33","14,21"
"low bq, many samples",UPN2_024,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),2536,447,3018,"0,148111332",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,54","14,14"
"low bq, many samples",UPN2_025,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),14699,2321,17238,"0,1346443903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,56","14,14"
"low bq, many samples",UPN2_026,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),14320,978,15426,"0,0633994555",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,99","14,13"
"low bq, many samples",UPN2_089,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),11246,873,12223,"0,0714227276",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,81","14,42"
"low bq, many samples",UPN2_043,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),1740,142,1908,"0,0744234801",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,24","14,36"
"low bq, many samples",UPN2_044,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),1456,214,1715,"0,1247813411",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,37","14,08"
"low bq, many samples",UPN2_029,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),9234,1556,10921,"0,1424777951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,51","14,16"
"low bq, many samples",UPN2_030,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),4837,798,5708,"0,1398037842",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,43","14,13"
"low bq, many samples",UPN2_031,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),7212,801,8092,"0,0989866535",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,66","14,1"
"low bq, many samples",UPN2_005,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),3678,303,3996,"0,0758258258",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,72","14,19"
"low bq, many samples",UPN2_045,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),5658,959,6785,"0,1413411938",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,46","14,19"
"low bq, many samples",UPN2_032,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),5594,459,6116,"0,0750490517",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,01","14,13"
"low bq, many samples",UPN2_046,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),6592,1121,7891,"0,1420605753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,49","14,27"
"low bq, many samples",UPN2_035,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),7233,554,7833,"0,0707264139",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,04","14,16"
"low bq, many samples",UPN2_036,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),6091,1021,7192,"0,1419632925",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,36","14,11"
"low bq, many samples",UPN2_006,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),293,40,336,"0,119047619",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,72","14,65"
"low bq, many samples",UPN2_049,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),1927,318,2288,"0,138986014",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,5","14,17"
"low bq, many samples",UPN2_050,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),5531,877,6581,"0,1332624221",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,39","14,2"
"low bq, many samples",UPN2_039,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),4428,694,5199,"0,1334872091",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,34","14,13"
"low bq, many samples",UPN2_053,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),13162,1382,14806,"0,0933405376",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,64","14,21"
"low bq, many samples",UPN2_007,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),14441,2326,16866,"0,1379105894",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,79","14,24"
"low bq, many samples",UPN2_009,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),25352,3991,29538,"0,1351140903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,75","14,23"
"low bq, many samples",UPN2_010,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),25771,2069,27965,"0,0739853388",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,52","14,27"
"low bq, many samples",UPN2_011,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),21508,1552,23133,"0,0670903039",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,16","14,33"
"low bq, many samples",UPN2_055,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),2655,215,2910,"0,0738831615",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,56","14,37"
"low bq, many samples",UPN2_057,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),8584,1465,10252,"0,1428989465",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,47","14,29"
"low bq, many samples",UPN2_058,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),7673,1288,9163,"0,140565317",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,56","14,31"
"low bq, many samples",UPN2_060,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),2424,349,2829,"0,1233651467",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,31","14,61"
"low bq, many samples",UPN2_040,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),6575,471,7123,"0,0661238242",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,3","14,1"
"low bq, many samples",UPN2_013,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),3525,588,4143,"0,1419261405",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,93","14,25"
"low bq, many samples",UPN2_091,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),1009,182,1210,"0,1504132231",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,56","14,52"
"low bq, many samples",UPN2_093,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),8122,661,8830,"0,0748584371",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,63","14,57"
"low bq, many samples",UPN2_061,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),22128,3213,25840,"0,1243421053",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,17","14,6"
"low bq, many samples",UPN2_062,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),13006,1829,15156,"0,1206782792",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,1","14,57"
"low bq, many samples",UPN2_068,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),21606,3246,25323,"0,1281838645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,17","14,53"
"low bq, many samples",UPN2_071,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),6847,1108,8076,"0,137196632",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,33","14,58"
"low bq, many samples",UPN2_073,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),192,42,236,"0,1779661017",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,32","14,17"
"low bq, many samples",UPN2_079,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),6887,517,7477,"0,0691453792",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,76","14,54"
"low bq, many samples",UPN2_083,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),8451,1178,9841,"0,1197032822",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,01","14,69"
"low bq, many samples",UPN2_084,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),18025,2847,21243,"0,1340206186",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,15","14,59"
"low bq, many samples",UPN2_085,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),6759,1073,7974,"0,1345623276",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,31","14,45"
"low bq, many samples",UPN2_087,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),14758,2521,17552,"0,1436303555",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,36","14,59"
"low bq, many samples",UPN2_088,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),24719,3775,28996,"0,1301903711",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,12","14,62"
"low bq, many samples",UPN2_094,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),5694,201,5920,"0,0339527027",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,35","14,52"
"low bq, many samples",UPN2_095,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),12410,1126,13651,"0,0824847996",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,41","14,48"
"low bq, many samples",UPN2_096,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),11581,2355,14123,"0,1667492742",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,93","14,6"
"low bq, many samples",UPN2_097,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),9550,362,9948,"0,036389224",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,07","15,34"
"low bq, many samples",UPN2_098,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),3480,560,4116,"0,1360544218",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,56","14,54"
"low bq, many samples",UPN2_100,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),7970,1495,9589,"0,155907811",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,58","14,54"
"low bq, many samples",UPN2_102,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),5349,917,6349,"0,144432194",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,46","14,49"
"low bq, many samples",UPN2_103,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),10633,748,11498,"0,0650547921",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,68","14,51"
"low bq, many samples",UPN2_104,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),5591,983,6663,"0,1475311421",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,59","14,53"
"low bq, low freq, many artifacts, many samples",UPN2_105,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),7023,85,7129,"0,0119231309",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,91","14,16"
"low bq, many samples",UPN2_106,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),751,139,907,"0,1532524807",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,6","14,77"
"low bq, many samples",UPN2_108,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),14058,1078,15259,"0,0706468314",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,76","14,58"
"low bq, many samples",UPN2_109,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),7985,1367,9507,"0,1437887872",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"27,57","14,46"
low bq,UPN2_111,X,15818036,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu55*/c.163G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),15435,1331,16931,"0,0786131947",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,57","14,54"
"inspected, many artifacts",UPN2_091,X,15818043,A,T,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln57Leu/c.170A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|T),1182,35,1217,"0,028759244",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,52",Deleterious,"0,199",Tolerated,"33,84","32,71"
"many samples, low freq, neutral effect",UPN2_014,X,15818069,A,G,missense_variant(MODERATE|MISSENSE|Aga/Gga|p.Arg66Gly/c.196A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|G),8990,101,9113,"0,0110830681",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,22",Neutral,"0,351",Tolerated,"34,68","34,57"
"many samples, low freq, neutral effect",UPN2_021,X,15818069,A,G,missense_variant(MODERATE|MISSENSE|Aga/Gga|p.Arg66Gly/c.196A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|G),6296,70,6402,"0,0109340831",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,22",Neutral,"0,351",Tolerated,"34,7","34,34"
"many samples, low freq, neutral effect",UPN2_033,X,15818069,A,G,missense_variant(MODERATE|MISSENSE|Aga/Gga|p.Arg66Gly/c.196A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|G),5681,59,5750,"0,0102608696",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,22",Neutral,"0,351",Tolerated,"34,74","34,41"
"many samples, low freq, neutral effect",UPN2_052,X,15818069,A,G,missense_variant(MODERATE|MISSENSE|Aga/Gga|p.Arg66Gly/c.196A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|G),7584,86,7696,"0,0111746362",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,22",Neutral,"0,351",Tolerated,"34,12","32,51"
"many samples, low freq, neutral effect",UPN2_038,X,15818069,A,G,missense_variant(MODERATE|MISSENSE|Aga/Gga|p.Arg66Gly/c.196A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|G),11139,119,11285,"0,0105449712",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,22",Neutral,"0,351",Tolerated,"34,72","34,13"
"many samples, low freq, neutral effect",UPN2_053,X,15818069,A,G,missense_variant(MODERATE|MISSENSE|Aga/Gga|p.Arg66Gly/c.196A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|G),14744,162,14966,"0,0108245356",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,22",Neutral,"0,351",Tolerated,"34,22","33,48"
"low freq, many artifacts",UPN2_057,X,15818069,A,G,missense_variant(MODERATE|MISSENSE|Aga/Gga|p.Arg66Gly/c.196A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|G),10251,105,10396,"0,0101000385",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,22",Neutral,351,Tolerated,"34,01","33,34"
"many samples, low freq, neutral effect",UPN2_092,X,15818069,A,G,missense_variant(MODERATE|MISSENSE|Aga/Gga|p.Arg66Gly/c.196A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|G),6728,75,6813,"0,0110083664",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,22",Neutral,"0,351",Tolerated,"34,61","32,45"
"many samples, low freq, neutral effect",UPN2_074,X,15818069,A,G,missense_variant(MODERATE|MISSENSE|Aga/Gga|p.Arg66Gly/c.196A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|G),5500,59,5573,"0,0105867576",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,22",Neutral,"0,351",Tolerated,"34,1","32,25"
"many samples, low freq, neutral effect",UPN2_099,X,15818069,A,G,missense_variant(MODERATE|MISSENSE|Aga/Gga|p.Arg66Gly/c.196A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|3|G),3345,37,3384,"0,0109338061",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,22",Neutral,"0,351",Tolerated,"34,7",32
"low freq, many artifacts",UPN2_058,X,15821814,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln69His/c.207A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|T),1971,28,2007,"0,0139511709",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,93",Neutral,"0,017",Damaging,"35,8","34,43"
"low freq, many artifacts",UPN2_007,X,15821816,G,A,missense_variant(MODERATE|MISSENSE|aGa/aAa|p.Arg70Lys/c.209G>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|A),2299,29,2330,"0,0124463519",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,22",Neutral,"0,698",Tolerated,"35,52","35,86"
"low freq, many artifacts",UPN2_060,X,15821821,C,T,missense_variant(MODERATE|MISSENSE|Cat/Tat|p.His72Tyr/c.214C>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|T),1165,20,1188,"0,0168350168",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,48",Deleterious,"0,002",Damaging,"35,11","33,8"
"low freq, many artifacts",UPN2_085,X,15821821,C,T,missense_variant(MODERATE|MISSENSE|Cat/Tat|p.His72Tyr/c.214C>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|T),1747,20,1768,"0,0113122172",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,48",Deleterious,"0,002",Damaging,"35,32",36
"inspected, many artifacts",UPN2_001,X,15821832,G,T,missense_variant(MODERATE|MISSENSE|tgG/tgT|p.Trp75Cys/c.225G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|T),1077,25,1102,"0,0226860254",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-8,89",Deleterious,0,Damaging,"35,25","34,96"
"low freq, many artifacts",UPN2_085,X,15821840,G,A,missense_variant(MODERATE|MISSENSE|aGa/aAa|p.Arg78Lys/c.233G>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|A),1742,26,1768,"0,0147058824",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,61",Neutral,"0,299",Tolerated,"35,28","35,85"
"low freq, many artifacts",UPN2_007,X,15821844,G,T,missense_variant(MODERATE|MISSENSE|gaG/gaT|p.Glu79Asp/c.237G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|T),2289,42,2347,"0,0178951853",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,3",Neutral,0,Damaging,"35,33","33,4"
"low bq, low freq, many artifacts",UPN2_051,X,15821849,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys81Met/c.242A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|T),2388,27,2424,"0,0111386139",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,13",Neutral,8,Damaging,"31,6","23,74"
"low freq, many artifacts",UPN2_062,X,15821854,C,A,missense_variant(MODERATE|MISSENSE|Caa/Aaa|p.Gln83Lys/c.247C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|A),2809,29,2842,"0,0102040816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,0,NO,NO,"-2,66",Deleterious,56,Tolerated,"32,3","30,93"
"low freq, many artifacts",UPN2_040,X,15821854,C,T,stop_gained(HIGH|NONSENSE|Caa/Taa|p.Gln83*/c.247C>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|T),2612,31,2644,"0,0117246596",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,42","34,77"
"low freq, many artifacts",UPN2_065,X,15821855,A,G,missense_variant(MODERATE|MISSENSE|cAa/cGa|p.Gln83Arg/c.248A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),1940,23,1964,"0,0117107943",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,59",Deleterious,"0,06",Tolerated,"33,57","31,87"
"low freq, many artifacts",UPN2_043,X,15821855,A,T,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln83Leu/c.248A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|T),3270,41,3319,"0,0123531184",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,"0,002",Damaging,"33,15","26,9"
"low freq, many artifacts",UPN2_083,X,15821855,A,T,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln83Leu/c.248A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|T),4663,55,4731,"0,0116254492",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,36",Deleterious,"0,002",Damaging,"33,57","31,71"
"low freq, many artifacts",UPN2_006,X,15821858,A,T,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu84Val/c.251A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|T),2342,43,2386,"0,0180217938",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,-4,Deleterious,"0,01",Damaging,"34,59","32,77"
inspected,UPN2_090,X,15821860,G,A,missense_variant(MODERATE|MISSENSE|Gaa/Aaa|p.Glu85Lys/c.253G>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|A),2064,63,2128,"0,0296052632",0,0,0,0,1,1,0,1,3,NO,NO,COSM4385279,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-2,23",Neutral,"0,01",Damaging,"33,26","34,7"
"low freq, many artifacts",UPN2_036,X,15821861,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu85Gly/c.254A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),1905,22,1930,"0,0113989637",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,54",Deleterious,"0,003",Damaging,"34,62","32,68"
"low freq, many artifacts",UPN2_019,X,15821863,T,C,missense_variant(MODERATE|MISSENSE|Ttc/Ctc|p.Phe86Leu/c.256T>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|C),1973,21,1997,"0,0105157737",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,41",Deleterious,"0,009",Damaging,"34,3","33,71"
"low freq, many artifacts",UPN2_054,X,15821866,A,G,missense_variant(MODERATE|MISSENSE|Aga/Gga|p.Arg87Gly/c.259A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),2022,25,2053,"0,0121773015",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,89",Deleterious,"0,012",Damaging,"33,91","29,4"
"low freq, many artifacts",UPN2_007,X,15821867,G,T,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg87Ile/c.260G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|T),4555,52,4609,"0,0112822738",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,32",Deleterious,"0,007",Damaging,"34,39","27,92"
"low freq, many artifacts",UPN2_051,X,15821869,A,G,missense_variant(MODERATE|MISSENSE|Ata/Gta|p.Ile88Val/c.262A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),2402,28,2437,"0,0114895363",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,2",Neutral,"0,726",Tolerated,"33,07","31,86"
"low freq, many artifacts",UPN2_006,X,15821872,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys89Glu/c.265A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),2346,32,2386,"0,0134115675",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,29",Neutral,"0,104",Tolerated,"34,43","34,03"
"low freq, many artifacts",UPN2_093,X,15821872,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys89*/c.265A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|T),3021,33,3064,"0,010770235",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,65","34,58"
"inspected, many artifacts",UPN2_044,X,15821873,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys89Met/c.266A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|T),782,34,824,"0,0412621359",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,015",Damaging,"33,46","33,97"
"low freq, many artifacts",UPN2_057,X,15821873,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys89Met/c.266A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|T),3142,54,3207,"0,0168381665",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,31",Neutral,"0,015",Damaging,"33,59","32,93"
"low freq, many artifacts",UPN2_080,X,15821875,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys90Glu/c.268A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),2114,26,2148,"0,0121042831",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,96",Neutral,"0,012",Damaging,"34,3","33,54"
"low freq, many artifacts",UPN2_035,X,15821881,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys92Glu/c.274A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),3968,60,4040,"0,0148514851",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,046",Damaging,"34,19","35,22"
"low freq, many artifacts",UPN2_050,X,15821881,A,G,missense_variant(MODERATE|MISSENSE|Aag/Gag|p.Lys92Glu/c.274A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),1989,30,2031,"0,0147710487",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,79",Neutral,"0,046",Damaging,"33,4","35,3"
"many samples, low freq, neutral effect",UPN2_019,X,15821882,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys92Arg/c.275A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),1972,20,1999,"0,0100050025",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,4",Tolerated,"34,01","34,7"
"many samples, low freq, neutral effect",UPN2_043,X,15821882,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys92Arg/c.275A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),3248,65,3325,"0,0195488722",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,4",Tolerated,"33,52","32,29"
"many samples, low freq, neutral effect",UPN2_031,X,15821882,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys92Arg/c.275A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),2603,30,2639,"0,0113679424",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,4",Tolerated,"34,27","34,83"
"many samples, low freq, neutral effect",UPN2_032,X,15821882,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys92Arg/c.275A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),1942,27,1978,"0,0136501517",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,4",Tolerated,"33,91","34,41"
"many samples, low freq, neutral effect",UPN2_035,X,15821882,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys92Arg/c.275A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),3988,46,4041,"0,011383321",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,4",Tolerated,"34,09","32,02"
"many samples, low freq, neutral effect",UPN2_051,X,15821882,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys92Arg/c.275A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),2403,27,2439,"0,0110701107",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,4",Tolerated,"33,62","33,63"
"many samples, low freq, neutral effect",UPN2_038,X,15821882,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys92Arg/c.275A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),4137,73,4215,"0,0173190985",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,4",Tolerated,"34,09","33,33"
"low freq, many artifacts, many samples",UPN2_039,X,15821882,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys92Arg/c.275A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),1930,20,1952,"0,0102459016",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,4",Tolerated,"34,17","34,5"
"low freq, many artifacts, many samples",UPN2_053,X,15821882,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys92Arg/c.275A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),6048,64,6130,"0,0104404568",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,4",Tolerated,"33,61","32,77"
"many samples, low freq, neutral effect",UPN2_054,X,15821882,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys92Arg/c.275A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),2024,22,2053,"0,0107160253",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,4",Tolerated,"33,62","32,27"
"many samples, low freq, neutral effect",UPN2_007,X,15821882,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys92Arg/c.275A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),4549,50,4613,"0,0108389334",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,4",Tolerated,"34,28","33,58"
"many samples, low freq, neutral effect",UPN2_011,X,15821882,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys92Arg/c.275A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),8745,97,8855,"0,0109542631",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,4",Tolerated,"34,28","34,36"
"many samples, low freq, neutral effect",UPN2_090,X,15821882,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys92Arg/c.275A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),2097,28,2128,"0,0131578947",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,4",Tolerated,"33,89","32,71"
"many samples, low freq, neutral effect",UPN2_040,X,15821882,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys92Arg/c.275A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),2583,43,2648,"0,0162386707",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,4",Tolerated,"34,24","34,19"
"many samples, low freq, neutral effect",UPN2_091,X,15821882,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys92Arg/c.275A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),1722,28,1758,"0,01592719",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,4",Tolerated,"33,72","32,36"
"many samples, low freq, neutral effect",UPN2_092,X,15821882,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys92Arg/c.275A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),2445,27,2474,"0,0109135004",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,4",Tolerated,"33,87","34,11"
"many samples, low freq, neutral effect",UPN2_061,X,15821882,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys92Arg/c.275A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),9242,96,9380,"0,0102345416",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,4",Tolerated,"33,03","33,77"
"low freq, many artifacts, many samples",UPN2_068,X,15821882,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys92Arg/c.275A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),7764,80,7857,"0,0101820033",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,4",Tolerated,"33,26","31,96"
"many samples, low freq, neutral effect",UPN2_071,X,15821882,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys92Arg/c.275A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),1358,24,1385,"0,0173285199",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,4",Tolerated,"33,04","31,38"
"many samples, low freq, neutral effect",UPN2_072,X,15821882,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys92Arg/c.275A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),1509,24,1537,"0,0156148341",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,4",Tolerated,"33,22","33,75"
"many samples, low freq, neutral effect",UPN2_075,X,15821882,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys92Arg/c.275A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),3728,50,3784,"0,0132135307",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,4",Tolerated,"33,16","33,14"
"many samples, low freq, neutral effect",UPN2_079,X,15821882,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys92Arg/c.275A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),4122,43,4180,"0,0102870813",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,4",Tolerated,"33,02","31,84"
"many samples, low freq, neutral effect",UPN2_083,X,15821882,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys92Arg/c.275A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),4673,48,4736,"0,0101351351",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,4",Tolerated,"33,05","32,35"
"many samples, low freq, neutral effect",UPN2_088,X,15821882,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys92Arg/c.275A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),7005,72,7098,"0,0101437025",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,4",Tolerated,"33,14","33,54"
"many samples, low freq, neutral effect",UPN2_096,X,15821882,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys92Arg/c.275A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),5618,64,5690,"0,0112478032",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,4",Tolerated,"34,02","33,16"
"many samples, low freq, neutral effect",UPN2_107,X,15821882,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys92Arg/c.275A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),4374,46,4429,"0,0103860917",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,45",Neutral,"0,4",Tolerated,"33,97","33,3"
"low freq, neutral effect",UPN2_072,X,15821884,G,A,missense_variant(MODERATE|MISSENSE|Gaa/Aaa|p.Glu93Lys/c.277G>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|A),1492,44,1537,"0,0286271958",0,0,0,0,1,1,0,1,3,NO,NO,COSM1315392,urinary_tract,2,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,348",Tolerated,"33,32","34,55"
"low freq, many artifacts",UPN2_044,X,15821885,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu93Gly/c.278A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),792,26,825,"0,0315151515",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,7",Deleterious,"0,018",Damaging,"34,06","32,31"
"low freq, many artifacts",UPN2_046,X,15821885,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu93Gly/c.278A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),2726,30,2770,"0,0108303249",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,7",Deleterious,"0,018",Damaging,"34,1","30,63"
"inspected, many artifacts",UPN2_072,X,15821887,G,T,stop_gained(HIGH|NONSENSE|Gag/Tag|p.Glu94*/c.280G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|T),1500,34,1537,"0,022121015",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,15","34,32"
"low freq, many artifacts",UPN2_091,X,15821893,G,A,missense_variant(MODERATE|MISSENSE|Gct/Act|p.Ala96Thr/c.286G>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|A),1718,32,1758,"0,0182025028",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,12",Neutral,"0,058",Tolerated,"32,23","33,12"
"low freq, many artifacts",UPN2_044,X,15821894,C,A,missense_variant(MODERATE|MISSENSE|gCt/gAt|p.Ala96Asp/c.287C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|A),788,37,826,"0,0447941889",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,88",Deleterious,"0,021",Damaging,"31,79","32,35"
"low freq, many artifacts, many samples",UPN2_016,X,15821895,TA,T,frameshift_variant(HIGH||aaa/|p.Lys98fs/c.294delA|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|T|INFO_REALIGN_3_PRIME),1830,26,1867,"0,0139260846",0,0,0,0,0,0,0,1,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,88",NA
"low freq, many artifacts, many samples",UPN2_002,X,15821895,TA,T,frameshift_variant(HIGH||aaa/|p.Lys98fs/c.294delA|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|T|INFO_REALIGN_3_PRIME),3983,47,4037,"0,0116423086",0,0,0,0,0,0,0,1,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,45",NA
"low freq, many artifacts, many samples",UPN2_024,X,15821895,TA,T,frameshift_variant(HIGH||aaa/|p.Lys98fs/c.294delA|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|T|INFO_REALIGN_3_PRIME),1273,20,1301,"0,0153727902",0,0,0,0,0,0,0,1,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,65",NA
"low freq, many artifacts, many samples",UPN2_025,X,15821895,TA,T,frameshift_variant(HIGH||aaa/|p.Lys98fs/c.294delA|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|T|INFO_REALIGN_3_PRIME),5179,59,5255,"0,0112274025",0,0,0,0,0,0,0,1,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,75",NA
"low freq, many artifacts, many samples",UPN2_046,X,15821895,TA,T,frameshift_variant(HIGH||aaa/|p.Lys98fs/c.294delA|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|T|INFO_REALIGN_3_PRIME),2736,32,2776,"0,0115273775",0,0,0,0,0,0,0,1,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,43",NA
"low freq, many artifacts, many samples",UPN2_036,X,15821895,TA,T,frameshift_variant(HIGH||aaa/|p.Lys98fs/c.294delA|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|T|INFO_REALIGN_3_PRIME),1898,28,1933,"0,0144852561",0,0,0,0,0,0,0,1,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,94",NA
many samples,UPN2_092,X,15821895,TA,T,frameshift_variant(HIGH||aaa/|p.Lys98fs/c.294delA|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|T|INFO_REALIGN_3_PRIME),2409,61,2477,"0,0246265644",0,0,0,0,0,0,0,1,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,1",NA
"low freq, many artifacts, many samples",UPN2_062,X,15821895,TA,T,frameshift_variant(HIGH||aaa/|p.Lys98fs/c.294delA|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|T|INFO_REALIGN_3_PRIME),2805,29,2846,"0,01018974",0,0,0,0,0,0,0,1,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,3",NA
"low freq, many artifacts, many samples",UPN2_076,X,15821895,TA,T,frameshift_variant(HIGH||aaa/|p.Lys98fs/c.294delA|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|T|INFO_REALIGN_3_PRIME),2965,38,3011,"0,0126203919",0,0,0,0,0,0,0,1,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,22",NA
"low freq, many artifacts, many samples",UPN2_079,X,15821895,TA,T,frameshift_variant(HIGH||aaa/|p.Lys98fs/c.294delA|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|T|INFO_REALIGN_3_PRIME),4126,46,4183,"0,0109968922",0,0,0,0,0,0,0,1,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,18",NA
"low freq, many artifacts, many samples",UPN2_094,X,15821895,TA,T,frameshift_variant(HIGH||aaa/|p.Lys98fs/c.294delA|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|T|INFO_REALIGN_3_PRIME),2847,33,2894,"0,0114029026",0,0,0,0,0,0,0,1,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,12",NA
"low freq, many artifacts, many samples",UPN2_096,X,15821895,TA,T,frameshift_variant(HIGH||aaa/|p.Lys98fs/c.294delA|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|T|INFO_REALIGN_3_PRIME),5626,59,5693,"0,0103636044",0,0,0,0,0,0,0,1,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,01",NA
"inspected, homopolymer 6A, different dels",UPN2_098,X,15821895,TA,T,frameshift_variant(HIGH||aaa/|p.Lys98fs/c.294delA|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|T|INFO_REALIGN_3_PRIME),1426,44,1473,"0,0298710115",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,12",NA
"low freq, many artifacts",UPN2_101,X,15821895,TA,T,frameshift_variant(HIGH||aaa/|p.Lys98fs/c.294delA|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|T|INFO_REALIGN_3_PRIME),2480,30,2517,"0,0119189511",0,0,0,0,0,0,0,1,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,14",NA
"low freq, many artifacts",UPN2_057,X,15821898,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys97Asn/c.291A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|T),3129,66,3212,"0,0205479452",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,92",Neutral,"0,017",Damaging,"34,15","32,24"
"low freq, many artifacts",UPN2_028,X,15821899,A,G,missense_variant(MODERATE|MISSENSE|Aaa/Gaa|p.Lys98Glu/c.292A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),2322,24,2350,"0,010212766",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,2",Neutral,"0,119",Tolerated,"34,32","33,96"
"low freq, many artifacts",UPN2_039,X,15821899,A,G,missense_variant(MODERATE|MISSENSE|Aaa/Gaa|p.Lys98Glu/c.292A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),1917,30,1951,"0,0153767299",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,2",Neutral,"0,119",Tolerated,"34,64","33,9"
"low freq, many artifacts",UPN2_090,X,15821899,A,G,missense_variant(MODERATE|MISSENSE|Aaa/Gaa|p.Lys98Glu/c.292A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),2096,32,2128,"0,015037594",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,2",Neutral,"0,119",Tolerated,"32,83","33,16"
"low bq, low freq, many artifacts",UPN2_075,X,15821901,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys98Asn/c.294A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|C),3729,38,3786,"0,0100369783",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,59",Deleterious,19,Damaging,"29,13","25,71"
"low freq, many artifacts",UPN2_050,X,15821906,A,G,missense_variant(MODERATE|MISSENSE|cAa/cGa|p.Gln100Arg/c.299A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),1994,34,2037,"0,0166912126",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,"0,265",Tolerated,"33,79","32,32"
"low freq, many artifacts",UPN2_057,X,15821906,A,G,missense_variant(MODERATE|MISSENSE|cAa/cGa|p.Gln100Arg/c.299A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),3168,35,3215,"0,0108864697",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,"0,265",Tolerated,"33,97","33,6"
"low freq, many artifacts",UPN2_092,X,15821906,A,G,missense_variant(MODERATE|MISSENSE|cAa/cGa|p.Gln100Arg/c.299A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),2434,33,2474,"0,0133387227",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,"0,265",Tolerated,"34,01","34,15"
"low freq, many artifacts",UPN2_071,X,15821906,A,G,missense_variant(MODERATE|MISSENSE|cAa/cGa|p.Gln100Arg/c.299A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),1360,24,1385,"0,0173285199",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,"0,265",Tolerated,"32,63","30,83"
"low freq, many artifacts",UPN2_072,X,15821909,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu101Gly/c.302A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|G),1504,33,1540,"0,0214285714",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,25",Deleterious,"0,043",Damaging,"33,65","31,24"
"low freq, many artifacts",UPN2_044,X,15821911,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu102*/c.304G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|T),732,85,825,"0,103030303",0,1,0,0,1,1,0,1,4,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,8","33,06"
"inspected, many artifacts",UPN2_049,X,15821913,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu102Asp/c.306A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|T),605,25,633,"0,0394944708",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,15",Neutral,"0,009",Damaging,"32,15","30,92"
"low freq, many artifacts",UPN2_046,X,15822233,G,T,splice_acceptor_variant+intron_variant(HIGH|||c.313-1G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|4|T),2371,25,2398,"0,0104253545",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,,,,,"35,57","35,4"
"low freq, many artifacts",UPN2_057,X,15822237,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys106*/c.316A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|5|T),2583,38,2632,"0,01443769",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,4","35,79"
"inspected, many artifacts",UPN2_047,X,15822239,G,T,missense_variant(MODERATE|MISSENSE|aaG/aaT|p.Lys106Asn/c.318G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|5|T),1553,35,1589,"0,0220264317",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,33",Neutral,"0,092",Tolerated,"35,47","35,34"
"low freq, many artifacts",UPN2_036,X,15822253,G,A,stop_gained(HIGH|NONSENSE|tGg/tAg|p.Trp111*/c.332G>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|5|A),2104,26,2131,"0,0122008447",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,28",36
"low freq, many artifacts",UPN2_044,X,15822264,C,T,stop_gained(HIGH|NONSENSE|Cag/Tag|p.Gln115*/c.343C>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|5|T),956,21,980,"0,0214285714",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,41","34,33"
"inspected, AG repeat",UPN2_012,X,15822271,AAG,A,frameshift_variant(HIGH||gaa/|p.Glu120fs/c.358_359delGA|482|ZRSR2|protein_coding|CODING|ENST00000307771|5|A|INFO_REALIGN_3_PRIME),995,24,1024,"0,0234375",0,0,0,1,0,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,74",NA
"low freq, many artifacts, not in 2nd illumina",UPN2_006,X,15822293,G,T,missense_variant(MODERATE|MISSENSE|caG/caT|p.Gln124His/c.372G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|5|T),1870,67,1942,"0,0345005149",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,"0,041",Damaging,"35,24","33,46"
"low freq, many artifacts",UPN2_050,X,15822294,A,T,stop_gained(HIGH|NONSENSE|Aaa/Taa|p.Lys125*/c.373A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|5|T),1849,21,1877,"0,0111880661",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,82","34,57"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_060,X,15822296,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys125Asn/c.375A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|5|C),4099,44,4173,"0,0105439732",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,34",Deleterious,"0,03",Damaging,"22,84",15
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_070,X,15822296,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys125Asn/c.375A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|5|C),6427,74,6535,"0,0113236419",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,34",Deleterious,"0,03",Damaging,"22,76","14,19"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,X,15822296,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys125Asn/c.375A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|5|C),4190,44,4257,"0,0103359173",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,34",Deleterious,"0,03",Damaging,"22,79","14,5"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,X,15822296,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys125Asn/c.375A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|5|C),4009,44,4075,"0,010797546",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,34",Deleterious,"0,03",Damaging,"22,47","16,07"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,X,15822296,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys125Asn/c.375A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|5|C),3259,34,3317,"0,0102502261",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,34",Deleterious,"0,03",Damaging,"22,69","14,38"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_081,X,15822296,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys125Asn/c.375A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|5|C),2829,33,2888,"0,0114265928",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,34",Deleterious,"0,03",Damaging,"22,91","14,21"
"low bq, bad alignment, low freq, many artifacts",UPN2_086,X,15822296,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys125Asn/c.375A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|5|C),5602,63,5702,"0,0110487548",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,34",Deleterious,"0,03",Damaging,"22,67","14,9"
"low freq, many artifacts",UPN2_010,X,15822297,C,T,stop_gained(HIGH|NONSENSE|Cga/Tga|p.Arg126*/c.376C>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|5|T),3628,37,3671,"0,0100789975",0,0,0,0,1,0,0,1,2,NO,NO,COSM4108324,stomach,1,NO,NO,NO,0,NO,NO,NA,NA,NA,NA,"35,01","35,05"
"low freq, many artifacts",UPN2_039,X,15822301,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln127Leu/c.380A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|5|T),1670,21,1700,"0,0123529412",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,63",Deleterious,"0,132",Tolerated,"34,77","33,76"
"low freq, many artifacts",UPN2_046,X,15822306,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys129*/c.385A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|5|T),2360,26,2397,"0,0108468919",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,61","32,5"
"low freq, many artifacts",UPN2_006,X,15822312,G,T,stop_gained(HIGH|NONSENSE|Gaa/Taa|p.Glu131*/c.391G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|5|T),1910,30,1941,"0,0154559505",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,28",35
"low freq, many artifacts",UPN2_090,X,15822318,G,A,missense_variant(MODERATE|MISSENSE|Gag/Aag|p.Glu133Lys/c.397G>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|5|A),1666,20,1686,"0,0118623962",0,0,0,0,0,0,0,1,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,68",Neutral,93,Tolerated,"35,25","31,1"
"low freq, many artifacts",UPN2_044,X,15826358,A,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu134Asp/c.402A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|6|T),2375,59,2441,"0,024170422",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,44",Neutral,"0,103",Tolerated,"35,69","35,19"
"low freq, many artifacts",UPN2_006,X,15826377,G,T,missense_variant(MODERATE|MISSENSE|Gat/Tat|p.Asp141Tyr/c.421G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|6|T),3683,39,3723,"0,010475423",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,98",Deleterious,"0,003",Damaging,"35,3","34,87"
"low bq, low freq, many artifacts, many samples",UPN2_060,X,15827348,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn155Thr/c.464A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|C),2571,31,2610,"0,0118773946",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,247,Tolerated,"28,63","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_061,X,15827348,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn155Thr/c.464A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|C),6718,69,6806,"0,0101381134",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,247,Tolerated,"28,21","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_062,X,15827348,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn155Thr/c.464A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|C),2488,30,2524,"0,0118858954",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,247,Tolerated,"28,31","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_063,X,15827348,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn155Thr/c.464A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|C),3049,36,3096,"0,011627907",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,247,Tolerated,"28,26","15,81"
"low bq, low freq, many artifacts, many samples",UPN2_065,X,15827348,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn155Thr/c.464A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|C),4537,49,4606,"0,0106382979",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,247,Tolerated,"28,49","15,27"
"low bq, low freq, many artifacts, many samples",UPN2_068,X,15827348,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn155Thr/c.464A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|C),7321,78,7420,"0,0105121294",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,247,Tolerated,"28,22","15,86"
"low bq, low freq, many artifacts, many samples",UPN2_069,X,15827348,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn155Thr/c.464A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|C),3234,37,3289,"0,0112496199",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,247,Tolerated,"28,29","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_070,X,15827348,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn155Thr/c.464A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|C),4505,53,4567,"0,0116049923",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,247,Tolerated,"28,31","16,3"
"low bq, low freq, many artifacts, many samples",UPN2_072,X,15827348,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn155Thr/c.464A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|C),1888,20,1913,"0,0104547831",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,247,Tolerated,"28,59","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_074,X,15827348,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn155Thr/c.464A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|C),4407,50,4469,"0,0111881853",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,247,Tolerated,"28,47","15,74"
"low bq, low freq, many artifacts, many samples",UPN2_076,X,15827348,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn155Thr/c.464A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|C),2232,36,2273,"0,0158380994",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,247,Tolerated,"27,91","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_077,X,15827348,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn155Thr/c.464A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|C),3621,46,3671,"0,0125306456",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,247,Tolerated,"28,57","15,61"
"low bq, low freq, many artifacts, many samples",UPN2_078,X,15827348,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn155Thr/c.464A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|C),2361,33,2404,"0,0137271215",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,247,Tolerated,"28,24","15,85"
"low bq, low freq, many artifacts, many samples",UPN2_079,X,15827348,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn155Thr/c.464A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|C),3287,45,3350,"0,0134328358",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,247,Tolerated,"28,47","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_081,X,15827348,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn155Thr/c.464A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|C),1545,21,1571,"0,013367282",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,247,Tolerated,"28,58","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_082,X,15827348,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn155Thr/c.464A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|C),7414,79,7526,"0,0104969439",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,247,Tolerated,"28,66","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_083,X,15827348,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn155Thr/c.464A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|C),4156,65,4244,"0,0153157399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,247,Tolerated,"28,05","15,97"
"low bq, low freq, many artifacts, many samples",UPN2_084,X,15827348,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn155Thr/c.464A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|C),4584,51,4655,"0,0109559613",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,247,Tolerated,"28,39","15,55"
"low bq, low freq, many artifacts, many samples",UPN2_085,X,15827348,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn155Thr/c.464A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|C),3169,36,3218,"0,0111870727",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,247,Tolerated,"28,59",15
"low bq, low freq, many artifacts, many samples",UPN2_086,X,15827348,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn155Thr/c.464A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|C),4218,52,4289,"0,0121240382",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,247,Tolerated,"28,51","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_087,X,15827348,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn155Thr/c.464A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|C),4326,63,4399,"0,0143214367",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,247,Tolerated,"28,54","14,75"
"low bq, low freq, many artifacts",UPN2_088,X,15827348,A,C,missense_variant(MODERATE|MISSENSE|aAc/aCc|p.Asn155Thr/c.464A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|C),6173,69,6272,"0,0110012755",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,25",Neutral,247,Tolerated,"29,07","15,43"
"low freq, many artifacts",UPN2_081,X,15827360,C,T,missense_variant(MODERATE|MISSENSE|cCc/cTc|p.Pro159Leu/c.476C>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|T),1541,24,1570,"0,0152866242",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,93",Deleterious,"0,567",Tolerated,"33,68","35,46"
"low freq, many artifacts",UPN2_072,X,15827389,C,T,stop_gained(HIGH|NONSENSE|Cga/Tga|p.Arg169*/c.505C>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|T),1885,21,1911,"0,010989011",0,0,0,0,1,0,0,1,2,NO,NO,COSM1716885,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,01","32,86"
"low bq, many samples",UPN2_001,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),6513,186,6722,"0,0276703362",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,76","15,1"
"low bq, many samples",UPN2_014,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),9794,231,10040,"0,0230079681",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,57","15,05"
"low bq, many samples",UPN2_015,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),13143,300,13464,"0,0222816399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,56","14,82"
"low bq, many samples",UPN2_016,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),6772,183,6969,"0,0262591477",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,44","14,34"
"low bq, many samples",UPN2_017,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),4792,121,4921,"0,0245884983",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,58","14,23"
"low bq, many samples",UPN2_018,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),6328,151,6485,"0,0232845027",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,49","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_019,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),7976,156,8141,"0,0191622651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,59","14,65"
"low bq, many samples",UPN2_020,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),6493,156,6665,"0,0234058515",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,5","14,81"
"low bq, many samples",UPN2_021,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),7204,190,7408,"0,0256479482",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,4","14,44"
"low bq, many samples",UPN2_002,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),18336,463,18830,"0,0245884227",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,9","14,96"
"low bq, many samples",UPN2_003,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),3750,105,3865,"0,0271668823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,77","15,72"
"low bq, many samples",UPN2_022,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),19550,479,20053,"0,0238867002",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,4","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_023,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),11610,256,11891,"0,0215288874",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,45","14,56"
"low bq, many samples",UPN2_024,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),5276,146,5439,"0,0268431697",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,24","14,65"
"low bq, many samples",UPN2_025,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),21690,506,22230,"0,0227620333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,46","14,61"
"low bq, many samples",UPN2_026,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),22977,519,23536,"0,0220513256",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,66","14,58"
"low bq, many samples",UPN2_004,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),978,28,1008,"0,0277777778",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,6","15,36"
"low bq, many samples",UPN2_027,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),13247,308,13572,"0,0226937813",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,59","14,61"
"low bq, many samples",UPN2_089,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),14597,464,15085,"0,0307590322",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,47","15,18"
"low bq, many samples",UPN2_042,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),18803,827,19671,"0,0420415841",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,25","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_028,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),9886,195,10096,"0,01931458",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,67","14,48"
"low bq, many samples",UPN2_043,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),18427,827,19320,"0,042805383",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,21","14,99"
"low bq, many samples",UPN2_044,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),7858,363,8241,"0,0440480524",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,22","14,82"
"low bq, many samples",UPN2_029,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),13344,334,13714,"0,0243546741",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,56","14,71"
"low bq, many samples",UPN2_030,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),11049,271,11338,"0,0239019227",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,44","14,76"
"low bq, many samples",UPN2_031,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),11941,320,12275,"0,0260692464",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,45","14,6"
"low bq, many samples",UPN2_005,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),5056,141,5206,"0,0270841337",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,88","14,98"
"low bq, many samples",UPN2_045,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),13716,535,14285,"0,0374518726",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,33","14,96"
"low bq, many samples",UPN2_032,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),8860,222,9091,"0,0244197558",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,39","14,59"
"low bq, many samples",UPN2_046,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),12138,452,12616,"0,0358275206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,26","14,74"
"low bq, many samples",UPN2_033,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),7804,198,8006,"0,0247314514",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,35","14,52"
"low bq, many samples",UPN2_034,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),3287,80,3377,"0,0236896654",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,77","14,59"
"low bq, many samples",UPN2_047,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),9563,415,10008,"0,0414668265",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,1","15,09"
"low bq, many samples",UPN2_035,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),23649,609,24291,"0,025071014",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,48","14,73"
"low bq, many samples",UPN2_036,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),16681,448,17166,"0,0260981009",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,56","14,76"
"low bq, many samples",UPN2_006,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),15382,421,15822,"0,0266085198",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,62","15,14"
"low bq, many samples",UPN2_049,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),8607,315,8955,"0,0351758794",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,4","14,99"
"low bq, many samples",UPN2_050,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),13411,498,13964,"0,0356631338",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,34","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_037,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),29139,655,29852,"0,0219415785",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,57","14,75"
"low bq, many samples",UPN2_051,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),10142,415,10581,"0,0392212456",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,27","15,04"
"low bq, many samples",UPN2_052,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),19878,745,20685,"0,036016437",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,37","15,19"
"low bq, many samples",UPN2_038,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),18361,429,18813,"0,0228033806",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,72","14,76"
"low bq, many samples",UPN2_039,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),12789,324,13137,"0,0246631651",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,64","14,85"
"low bq, many samples",UPN2_053,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),27820,1011,28891,"0,0349935966",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,37","15,12"
"low bq, many samples",UPN2_054,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),8939,331,9290,"0,0356297094",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,32","14,86"
"low bq, many samples",UPN2_007,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),19156,546,19735,"0,0276665822",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,53","15,37"
"low bq, many samples",UPN2_008,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),29950,758,30789,"0,0246191822",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,66","14,94"
"low bq, many samples",UPN2_009,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),50979,1356,52406,"0,0258748998",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,66","15,06"
"low bq, many samples",UPN2_010,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),30647,796,31492,"0,0252762606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,72","14,81"
"low bq, many samples",UPN2_011,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),36796,1022,37884,"0,026977088",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,56",15
"low bq, many samples",UPN2_055,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),26506,1078,27669,"0,0389605696",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,35","15,18"
"low bq, many samples",UPN2_056,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),1009,49,1060,"0,0462264151",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,91","14,51"
"low bq, many samples",UPN2_090,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),6427,215,6651,"0,032325966",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,53","14,76"
"low bq, many samples",UPN2_057,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),16469,671,17181,"0,0390547698",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,3","14,99"
"low bq, many samples",UPN2_058,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),15992,624,16655,"0,0374662264",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,1","15,02"
"low bq, many samples",UPN2_059,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),2562,80,2654,"0,0301431801",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,7","15,5"
"low bq, many samples",UPN2_012,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),9832,273,10122,"0,0269709544",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,5","15,23"
"low bq, many samples",UPN2_060,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),4897,144,5081,"0,0283408778",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,65","14,83"
"low bq, many samples",UPN2_040,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),21048,563,21650,"0,0260046189",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,46","14,86"
"low bq, many samples",UPN2_013,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),5152,174,5332,"0,0326331583",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,66","15,3"
"low bq, many samples",UPN2_091,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),6047,254,6311,"0,0402471875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,55","15,46"
"low bq, many samples",UPN2_092,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),8407,320,8741,"0,0366090836",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,5","15,32"
"low bq, many samples",UPN2_093,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),9327,395,9732,"0,0405877517",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,36","14,97"
"low bq, many samples",UPN2_061,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),12854,371,13284,"0,0279283348",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,72","15,11"
"low bq, many samples",UPN2_062,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),4773,128,4926,"0,0259845717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,61","14,81"
"low bq, many samples",UPN2_063,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),5889,178,6074,"0,0293052354",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,66","15,13"
"low bq, many samples",UPN2_064,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),6576,181,6768,"0,0267434988",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,6","14,99"
"low bq, many samples",UPN2_065,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),8713,262,8998,"0,0291175817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,5","15,32"
"low bq, many samples",UPN2_066,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),7360,227,7612,"0,0298213347",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,57","14,85"
"low bq, many samples",UPN2_067,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),8267,241,8529,"0,0282565365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,49","14,87"
"low bq, many samples",UPN2_068,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),14067,415,14520,"0,0285812672",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,61","14,98"
"low bq, many samples",UPN2_069,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),6205,191,6420,"0,0297507788",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,48","15,18"
"low bq, many samples",UPN2_070,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),8682,235,8955,"0,0262423227",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,73","15,04"
"low bq, many samples",UPN2_071,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),2949,97,3049,"0,0318137094",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,65","15,68"
"low bq, many samples",UPN2_072,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),3574,116,3711,"0,0312584209",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,68","15,52"
"low bq, many samples",UPN2_073,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),2886,88,2981,"0,0295202952",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,52","14,84"
"low bq, many samples",UPN2_074,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),8477,212,8704,"0,0243566176",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,67","15,04"
"low bq, many samples",UPN2_075,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),5305,151,5480,"0,0275547445",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,45","14,58"
"low bq, many samples",UPN2_076,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),4309,121,4438,"0,0272645336",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,62","14,84"
"low bq, many samples",UPN2_077,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),6954,187,7170,"0,0260808926",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,73","15,16"
"low bq, many samples",UPN2_078,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),4564,148,4721,"0,0313492904",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,62","15,04"
"low bq, many samples",UPN2_079,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),6371,185,6569,"0,0281625818",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,58","15,35"
"low bq, many samples",UPN2_080,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),3834,126,3967,"0,0317620368",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,74","15,12"
"low bq, many samples",UPN2_081,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),2958,105,3068,"0,0342242503",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,4","14,96"
"low bq, many samples",UPN2_082,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),14208,420,14669,"0,0286318086",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,67","15,27"
"low bq, many samples",UPN2_083,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),8082,230,8328,"0,0276176753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,69","14,95"
"low bq, many samples",UPN2_084,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),8790,267,9076,"0,0294182459",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,67","15,22"
"low bq, many samples",UPN2_085,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),6063,185,6266,"0,0295244175",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,69","15,26"
"low bq, many samples",UPN2_086,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),8137,240,8404,"0,0285578296",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,59","15,1"
"low bq, many samples",UPN2_087,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),8368,233,8620,"0,0270301624",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,61","14,71"
"low bq, many samples",UPN2_088,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),11848,384,12274,"0,0312856445",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,52","14,9"
"low bq, many samples",UPN2_094,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),7962,306,8286,"0,036929761",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,46","14,89"
"low bq, many samples",UPN2_095,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),15392,546,15952,"0,034227683",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,5","14,97"
"low bq, many samples",UPN2_096,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),16271,580,16883,"0,034354084",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,48","14,92"
"low bq, many samples",UPN2_097,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),14762,574,15358,"0,0373746582",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,39",15
"low bq, many samples",UPN2_098,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),6538,202,6750,"0,0299259259",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,56","14,94"
"low bq, many samples",UPN2_099,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),4063,142,4210,"0,0337292162",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,57","14,67"
"low bq, many samples",UPN2_100,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),12083,356,12465,"0,0285599679",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,2","14,67"
"low bq, many samples",UPN2_101,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),6868,186,7073,"0,0262971865",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,63","14,76"
"low bq, many samples",UPN2_102,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),7338,195,7549,"0,0258312359",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,51","15,05"
"low bq, many samples",UPN2_103,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),13607,388,14011,"0,0276925273",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,7","14,95"
"low bq, many samples",UPN2_104,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),8632,256,8899,"0,0287672772",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,67","14,96"
"low bq, many samples",UPN2_105,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),12394,372,12782,"0,0291034267",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,56","14,75"
"low bq, many samples",UPN2_106,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),7494,242,7752,"0,0312177503",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,42",15
"low bq, many samples",UPN2_107,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),13541,351,13920,"0,0252155172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,57","14,71"
"low bq, many samples",UPN2_108,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),18588,539,19163,"0,02812712",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,36","14,8"
"low bq, many samples",UPN2_109,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),9941,273,10241,"0,026657553",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,4","14,92"
"low bq, many samples",UPN2_110,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),10425,276,10714,"0,025760687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,55","14,61"
low bq,UPN2_111,X,15827409,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr175*/c.525C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|A),18351,515,18898,"0,027251561",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,5","14,71"
"low bq, low freq, many artifacts",UPN2_044,X,15827419,G,T,stop_gained(HIGH|NONSENSE|Gga/Tga|p.Gly179*/c.535G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|T),8172,132,8321,"0,0158634779",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,68","27,69"
"low bq, low freq, many artifacts",UPN2_047,X,15827419,G,T,stop_gained(HIGH|NONSENSE|Gga/Tga|p.Gly179*/c.535G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|T),9954,126,10105,"0,0124690747",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,79","27,13"
"low bq, low freq, many artifacts",UPN2_080,X,15827428,A,G,missense_variant(MODERATE|MISSENSE|Aga/Gga|p.Arg182Gly/c.544A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|G),3935,54,4012,"0,0134596211",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,72",Deleterious,0,Damaging,"32,67","29,41"
"low bq, low freq, many artifacts",UPN2_006,X,15827428,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg182*/c.544A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|7|T),15702,181,15951,"0,011347251",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,5","27,55"
"low freq, many artifacts",UPN2_044,X,15833802,G,C,missense_variant+splice_region_variant(MODERATE|MISSENSE|tGt/tCt|p.Cys187Ser/c.560G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|C),4915,55,5014,"0,010969286",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,8",Deleterious,0,Damaging,"35,24","35,36"
"inspected, many artifacts",UPN2_109,X,15833805,C,G,stop_gained(HIGH|NONSENSE|tCa/tGa|p.Ser188*/c.563C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),5583,130,5731,"0,0226836503",0,0,0,0,1,0,0,1,2,NO,NO,COSM4385286,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,5","34,79"
"low freq, many artifacts",UPN2_044,X,15833807,C,T,missense_variant(MODERATE|MISSENSE|Cgt/Tgt|p.Arg189Cys/c.565C>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|T),4951,58,5014,"0,0115676107",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,37",Deleterious,0,Damaging,"35,58","35,78"
"low freq, many artifacts",UPN2_006,X,15833807,C,T,missense_variant(MODERATE|MISSENSE|Cgt/Tgt|p.Arg189Cys/c.565C>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|T),11623,127,11753,"0,0108057517",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,37",Deleterious,0,Damaging,"35,67","35,83"
"low freq, many artifacts",UPN2_048,X,15833814,A,G,missense_variant(MODERATE|MISSENSE|cAt/cGt|p.His191Arg/c.572A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),2877,31,2917,"0,0106273569",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,84",Deleterious,0,Damaging,"35,72","35,71"
"low freq, many artifacts",UPN2_044,X,15833817,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn192Ile/c.575A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|T),4940,53,5014,"0,0105704029",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,21",Neutral,"0,204",Tolerated,"35,54","34,6"
"low freq, many artifacts",UPN2_044,X,15833838,C,T,missense_variant(MODERATE|MISSENSE|aCc/aTc|p.Thr199Ile/c.596C>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|T),4945,54,5010,"0,0107784431",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,35",Deleterious,"0,159",Tolerated,"34,96","34,35"
"low freq, many artifacts",UPN2_044,X,15833850,A,G,missense_variant(MODERATE|MISSENSE|aAg/aGg|p.Lys203Arg/c.608A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),4953,54,5010,"0,0107784431",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,43",Neutral,"0,691",Tolerated,"35,58","35,19"
"low freq, many artifacts",UPN2_048,X,15833862,C,T,missense_variant(MODERATE|MISSENSE|aCg/aTg|p.Thr207Met/c.620C>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|T),5631,107,5761,"0,0185731644",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,0,NO,NO,"-3,11",Deleterious,"0,006",Damaging,"32,56","34,5"
"low freq, many artifacts",UPN2_048,X,15833868,T,C,missense_variant(MODERATE|MISSENSE|tTt/tCt|p.Phe209Ser/c.626T>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|C),5685,65,5773,"0,0112593106",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,58",Deleterious,"0,004",Damaging,"33,33","32,82"
"low freq, many artifacts",UPN2_048,X,15833879,C,T,stop_gained(HIGH|NONSENSE|Cag/Tag|p.Gln213*/c.637C>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|T),5615,125,5773,"0,0216525204",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,06","33,92"
"low bq, low freq, many artifacts",UPN2_056,X,15833888,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg216Trp/c.646A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|T),4521,52,4578,"0,0113586719",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,25",Deleterious,"0,011",Damaging,"34,09","29,23"
"low freq, many artifacts",UPN2_044,X,15833898,A,G,missense_variant(MODERATE|MISSENSE|tAt/tGt|p.Tyr219Cys/c.656A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),9779,108,9922,"0,0108849022",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-7,9",Deleterious,"0,002",Damaging,"34,38","33,96"
"low freq, many artifacts",UPN2_004,X,15833909,G,T,missense_variant(MODERATE|MISSENSE|Gca/Tca|p.Ala223Ser/c.667G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|T),2226,26,2254,"0,0115350488",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,72",Neutral,"0,24",Tolerated,"33,53","31,15"
"low freq, many artifacts",UPN2_044,X,15833943,A,T,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln234Leu/c.701A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|T),4838,75,4920,"0,0152439024",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,"0,071",Tolerated,"34,24","24,8"
"low bq, low freq, many artifacts",UPN2_057,X,15833943,A,T,missense_variant(MODERATE|MISSENSE|cAa/cTa|p.Gln234Leu/c.701A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|T),8743,99,8863,"0,0111700327",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,71,Tolerated,"34,22","23,48"
"low freq, many artifacts",UPN2_044,X,15833944,A,T,missense_variant(MODERATE|MISSENSE|caA/caT|p.Gln234His/c.702A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|T),4816,80,4920,"0,0162601626",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,43",Neutral,"0,095",Tolerated,"33,8","27,49"
"low freq, many artifacts, many samples",UPN2_001,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),7570,101,7681,"0,0131493295",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"33,26","31,43"
"low freq, many artifacts, many samples",UPN2_014,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),10846,110,10973,"0,0100246059",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"33,52","31,74"
"low freq, many artifacts, many samples",UPN2_017,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),5038,54,5097,"0,0105944673",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"33,5","31,37"
"low freq, many artifacts, many samples",UPN2_019,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),8766,89,8867,"0,0100372166",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"33,48","30,08"
"low freq, many artifacts, many samples",UPN2_020,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),6796,73,6879,"0,0106120076",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"33,67","31,26"
"low freq, many artifacts, many samples",UPN2_021,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),8234,107,8355,"0,0128067026",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"33,58","30,68"
"low freq, many artifacts, many samples",UPN2_002,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),19486,284,19806,"0,0143390892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"33,33","30,88"
"low freq, many artifacts, many samples",UPN2_027,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),15017,191,15223,"0,0125468042",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"33,47","31,38"
"low freq, many artifacts, many samples",UPN2_028,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),10981,127,11125,"0,0114157303",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"33,5","31,72"
"low freq, many artifacts, many samples",UPN2_005,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),5820,81,5907,"0,0137125444",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"33,37","30,48"
"low freq, many artifacts, many samples",UPN2_048,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),9923,104,10045,"0,0103534097",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"32,26","30,22"
"low freq, many artifacts, many samples",UPN2_035,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),27343,323,27694,"0,0116631761",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"33,45","31,34"
"low freq, many artifacts, many samples",UPN2_036,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),13852,182,14050,"0,0129537367",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"33,47","30,98"
"low freq, many artifacts, many samples",UPN2_006,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),24176,523,24734,"0,0211449826",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"33,12","31,25"
"low freq, many artifacts, many samples",UPN2_039,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),14833,189,15043,"0,0125639832",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"33,39","31,26"
"low freq, many artifacts, many samples",UPN2_007,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),21802,291,22126,"0,0131519479",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"33,26","30,84"
"low freq, many artifacts, many samples",UPN2_008,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),29601,338,29997,"0,0112677934",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"33,32","31,09"
"low freq, many artifacts, many samples",UPN2_009,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),43093,451,43618,"0,010339768",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"33,33","31,06"
"low freq, many artifacts, many samples",UPN2_010,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),33613,407,34079,"0,0119428387",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"33,28","31,26"
"low freq, many artifacts, many samples",UPN2_011,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),41153,511,41732,"0,0122448002",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"33,32","31,03"
"low freq, many artifacts, many samples",UPN2_059,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),17675,228,17952,"0,0127005348",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"32,49","30,97"
"low freq, many artifacts, many samples",UPN2_012,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),8612,120,8745,"0,0137221269",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"33,25","30,71"
"low freq, many artifacts, many samples",UPN2_060,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),12957,287,13266,"0,021634253",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"32,57","31,18"
"low freq, many artifacts, many samples",UPN2_040,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),18792,239,19052,"0,0125446147",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"33,48","31,49"
"low freq, many artifacts, many samples",UPN2_013,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),5912,70,5994,"0,011678345",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"33,3","31,59"
"low freq, many artifacts, many samples",UPN2_061,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),24317,426,24773,"0,017196141",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"33,02","30,81"
"low freq, many artifacts, many samples",UPN2_062,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),11966,232,12213,"0,0189961516",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"32,84","30,77"
"low freq, many artifacts, many samples",UPN2_063,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),8842,194,9049,"0,021438833",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"32,85","30,74"
"low freq, many artifacts, many samples",UPN2_064,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),31266,682,31999,"0,021313166",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"32,69","30,79"
"low freq, many artifacts, many samples",UPN2_065,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),32114,503,32681,"0,0153912059",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"32,63","30,55"
"low freq, many artifacts, many samples",UPN2_066,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),17122,257,17426,"0,0147480776",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"32,75","30,72"
"low freq, many artifacts, many samples",UPN2_067,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),19679,272,19987,"0,0136088457",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"32,82","30,47"
"low freq, many artifacts, many samples",UPN2_068,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),26380,402,26816,"0,0149910501",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"32,84","30,31"
"low freq, many artifacts, many samples",UPN2_069,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),14782,239,15057,"0,0158730159",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"32,77","30,73"
"low freq, many artifacts, many samples",UPN2_070,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),19225,309,19581,"0,0157806036",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"32,74","30,55"
"low freq, many artifacts, many samples",UPN2_071,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),8367,165,8549,"0,019300503",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"32,67","30,76"
"low freq, many artifacts, many samples",UPN2_072,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),10867,232,11126,"0,0208520582",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"32,68","31,16"
"low freq, many artifacts, many samples",UPN2_073,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),10384,175,10583,"0,0165359539",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"32,63","30,43"
"low freq, many artifacts, many samples",UPN2_074,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),18439,317,18782,"0,0168778618",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"32,93","30,52"
"low freq, many artifacts, many samples",UPN2_075,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),14347,294,14655,"0,0200614125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"32,64","30,92"
"low freq, many artifacts, many samples",UPN2_076,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),12673,264,12958,"0,0203735144",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"32,58","30,7"
"low freq, many artifacts, many samples",UPN2_077,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),14750,281,15054,"0,0186661352",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"32,81","30,74"
"low freq, many artifacts, many samples",UPN2_078,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),11070,210,11295,"0,0185922975",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"32,72","30,88"
"low freq, many artifacts, many samples",UPN2_079,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),15665,299,15991,"0,0186980176",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"32,7","30,32"
"low freq, many artifacts, many samples",UPN2_080,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),11691,254,11964,"0,0212303577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"32,69","31,05"
"low freq, many artifacts, many samples",UPN2_081,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),16631,295,16971,"0,0173825938",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"32,74","30,47"
"low freq, many artifacts, many samples",UPN2_082,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),36726,522,37348,"0,013976652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"32,77","30,36"
"low freq, many artifacts, many samples",UPN2_083,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),16064,337,16435,"0,0205050198",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"32,84","30,82"
"low freq, many artifacts, many samples",UPN2_084,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),16806,269,17109,"0,015722719",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"32,72","31,07"
"low freq, many artifacts, many samples",UPN2_085,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),13919,217,14157,"0,0153281062",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"32,78","30,3"
"low freq, many artifacts, many samples",UPN2_086,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),21034,289,21363,"0,0135280625",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"32,68","30,46"
"low freq, many artifacts, many samples",UPN2_087,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),18784,312,19123,"0,0163154317",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"32,72","30,52"
"low freq, many artifacts",UPN2_088,X,15833956,C,G,missense_variant(MODERATE|MISSENSE|gaC/gaG|p.Asp238Glu/c.714C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|G),28278,484,28824,"0,0167915626",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,49",Neutral,1,Tolerated,"32,64","30,17"
"low bq, low freq, many artifacts",UPN2_048,X,15833991,T,A,missense_variant(MODERATE|MISSENSE|gTg/gAg|p.Val250Glu/c.749T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|A),9947,105,10114,"0,0103816492",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,6",Deleterious,13,Damaging,"34,36","26,63"
"low freq, many artifacts",UPN2_044,X,15833999,G,A,missense_variant(MODERATE|MISSENSE|Gtg/Atg|p.Val253Met/c.757G>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|A),7654,78,7738,"0,0100801241",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,54",Deleterious,2,Damaging,"35,26","34,28"
"low freq, many artifacts",UPN2_044,X,15834011,A,C,missense_variant+splice_region_variant(MODERATE|MISSENSE|Aag/Cag|p.Lys257Gln/c.769A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|8|C),2798,48,2863,"0,0167656305",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,55",Deleterious,31,Damaging,"34,94","30,96"
"low bq, low freq, many artifacts",UPN2_049,X,15836719,A,T,missense_variant(MODERATE|MISSENSE|Aat/Tat|p.Asn261Tyr/c.781A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|9|T),17674,181,17982,"0,0100656212",0,0,0,0,1,0,0,0,1,NO,NO,COSM211060,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-7,85",Deleterious,0,Damaging,"33,33","24,69"
"low freq, many artifacts",UPN2_056,X,15836719,A,T,missense_variant(MODERATE|MISSENSE|Aat/Tat|p.Asn261Tyr/c.781A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|9|T),9170,102,9351,"0,0109079243",0,0,0,0,1,0,0,1,2,NO,NO,COSM211060,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-7,85",Deleterious,0,Damaging,"33,32","27,84"
"low bq, low freq, many artifacts",UPN2_048,X,15836760,C,A,stop_gained(HIGH|NONSENSE|taC/taA|p.Tyr274*/c.822C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|9|A),8537,89,8666,"0,0102700208",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,44","14,99"
"low freq, many artifacts",UPN2_044,X,15836763,G,T,missense_variant+splice_region_variant(MODERATE|MISSENSE|caG/caT|p.Gln275His/c.825G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|9|T),7386,80,7500,"0,0106666667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,31",Neutral,21,Damaging,"34,37","30,21"
"low bq, low freq, many artifacts",UPN2_072,X,15838380,C,A,missense_variant(MODERATE|MISSENSE|gCa/gAa|p.Ala293Glu/c.878C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|10|A),2014,22,2041,"0,0107790299",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,42",Deleterious,2,Damaging,"32,12",18
"low freq, many artifacts",UPN2_044,X,15838392,T,C,missense_variant(MODERATE|MISSENSE|cTg/cCg|p.Leu297Pro/c.890T>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|10|C),2651,50,2713,"0,0184297825",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,22",Deleterious,0,Damaging,"32,58","32,86"
"low freq, many artifacts",UPN2_006,X,15838392,T,C,missense_variant(MODERATE|MISSENSE|cTg/cCg|p.Leu297Pro/c.890T>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|10|C),4188,43,4236,"0,0101510859",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,22",Deleterious,0,Damaging,"33,68","34,35"
"low freq, many artifacts",UPN2_071,X,15838395,A,G,missense_variant(MODERATE|MISSENSE|cAg/cGg|p.Gln298Arg/c.893A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|10|G),5171,55,5249,"0,0104781863",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,"0,198",Tolerated,"33,39","30,53"
"low freq, many artifacts",UPN2_047,X,15838395,A,T,missense_variant(MODERATE|MISSENSE|cAg/cTg|p.Gln298Leu/c.893A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|10|T),1982,34,2030,"0,0167487685",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,62",Deleterious,"0,073",Tolerated,"33,68","29,97"
"low freq, many artifacts",UPN2_045,X,15838397,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys299Arg/c.895T>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|10|C),3260,37,3321,"0,0111412225",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-9,71",Deleterious,"0,001",Damaging,"32,85","32,49"
"inspected, many artifacts",UPN2_049,X,15838398,G,T,missense_variant(MODERATE|MISSENSE|tGt/tTt|p.Cys299Phe/c.896G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|10|T),1817,44,1868,"0,0235546039",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,78",Deleterious,"0,002",Damaging,"33,68","33,05"
"low bq, low freq, many artifacts",UPN2_042,X,15838401,A,T,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu300Val/c.899A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|10|T),3863,49,3930,"0,0124681934",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,82",Deleterious,"0,002",Damaging,"33,59","28,31"
"low bq, low freq, many artifacts",UPN2_047,X,15838401,A,T,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu300Val/c.899A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|10|T),2005,23,2032,"0,0113188976",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,82",Deleterious,"0,002",Damaging,"33,55","26,87"
"low bq, low freq, many artifacts",UPN2_049,X,15838406,T,A,missense_variant(MODERATE|MISSENSE|Tgc/Agc|p.Cys302Ser/c.904T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|10|A),1827,35,1870,"0,0187165775",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-4,56",Deleterious,"0,237",Tolerated,"33,02","29,09"
"low freq, many artifacts",UPN2_006,X,15838406,T,C,missense_variant(MODERATE|MISSENSE|Tgc/Cgc|p.Cys302Arg/c.904T>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|10|C),4155,72,4237,"0,0169931555",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,73",Deleterious,"0,075",Tolerated,"34,31","32,76"
"low freq, many artifacts",UPN2_013,X,15838410,C,T,missense_variant(MODERATE|MISSENSE|cCc/cTc|p.Pro303Leu/c.908C>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|10|T),2109,22,2143,"0,0102659823",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-6,88",Deleterious,"0,009",Damaging,"32,18",32
"low freq, many artifacts",UPN2_045,X,15838415,A,G,missense_variant(MODERATE|MISSENSE|Acc/Gcc|p.Thr305Ala/c.913A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|10|G),3260,36,3324,"0,0108303249",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,21",Deleterious,"0,066",Tolerated,"32,04","30,11"
"low bq, low freq, many artifacts",UPN2_042,X,15838415,A,T,missense_variant(MODERATE|MISSENSE|Acc/Tcc|p.Thr305Ser/c.913A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|10|T),3873,41,3937,"0,0104140208",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,3",Neutral,124,Tolerated,"32,03","20,76"
"low bq, low freq, many artifacts",UPN2_052,X,15838419,G,T,missense_variant(MODERATE|MISSENSE|cGg/cTg|p.Arg306Leu/c.917G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|10|T),9171,98,9286,"0,0105535214",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-4,25",Deleterious,31,Damaging,"31,46","24,93"
"low freq, many artifacts",UPN2_049,X,15838424,A,G,missense_variant(MODERATE|MISSENSE|Aaa/Gaa|p.Lys308Glu/c.922A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|10|G),1826,24,1872,"0,0128205128",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,"0,014",Damaging,"34,1","33,75"
"low freq, many artifacts",UPN2_091,X,15838426,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys308Asn/c.924A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|10|T),3100,36,3147,"0,0114394662",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,44",Deleterious,"0,04",Damaging,"34,91","33,25"
"low freq, many artifacts",UPN2_090,X,15838429,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met309Ile/c.927G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|10|T),4342,44,4397,"0,0100068228",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,35",Neutral,228,Tolerated,"32,98","30,52"
"low freq, many artifacts",UPN2_090,X,15838431,C,T,missense_variant(MODERATE|MISSENSE|gCg/gTg|p.Ala310Val/c.929C>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|10|T),4326,54,4397,"0,0122811008",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,83",Deleterious,"0,002",Damaging,"32,67","32,69"
"low freq, many artifacts",UPN2_012,X,15838431,C,T,missense_variant(MODERATE|MISSENSE|gCg/gTg|p.Ala310Val/c.929C>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|10|T),3344,41,3393,"0,0120837017",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,83",Deleterious,"0,002",Damaging,"33,15","32,1"
"low bq, low freq, many artifacts",UPN2_013,X,15838433,A,T,missense_variant(MODERATE|MISSENSE|Att/Ttt|p.Ile311Phe/c.931A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|10|T),2097,31,2145,"0,0144522145",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,87",Deleterious,1,Damaging,"34,25","23,35"
"low freq, many artifacts",UPN2_047,X,15838436,T,C,missense_variant(MODERATE|MISSENSE|Tgt/Cgt|p.Cys312Arg/c.934T>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|10|C),2005,22,2034,"0,0108161259",0,0,0,0,1,0,0,1,2,NO,NO,COSM4385296,haematopoietic_and_lymphoid_tissue,1,NO,NO,NO,NO,NO,NO,"-11,52",Deleterious,0,Damaging,"33,73","32,36"
"low freq, many artifacts",UPN2_044,X,15840863,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu316Gly/c.947A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),3646,42,3706,"0,0113329736",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,98",Deleterious,"0,077",Tolerated,"35,19","35,71"
"low freq, many artifacts",UPN2_048,X,15840866,TAC,T,frameshift_variant(HIGH||caa/|p.Gln318fs/c.952_953delCA|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T|INFO_REALIGN_3_PRIME),2928,33,2971,"0,0111073713",0,0,0,1,1,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,69",NA
"low freq, many artifacts",UPN2_044,X,15840913,A,G,missense_variant(MODERATE|MISSENSE|Aga/Gga|p.Arg333Gly/c.997A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),3656,42,3705,"0,0113360324",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,1",Deleterious,"0,013",Damaging,"35,09","33,57"
"low bq, low freq, many artifacts",UPN2_064,X,15840920,C,A,missense_variant(MODERATE|MISSENSE|cCc/cAc|p.Pro335His/c.1004C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1766,22,1793,"0,0122699387",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-8,67",Deleterious,0,Damaging,"31,44",20
"low bq, low freq, many artifacts, many samples",UPN2_001,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),7641,91,7747,"0,0117464825",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,36","15,47"
"low bq, low freq, many artifacts, many samples",UPN2_014,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),9036,182,9244,"0,0196884466",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,92","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_015,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),12258,194,12481,"0,0155436263",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,19","15,9"
"low bq, low freq, many artifacts, many samples",UPN2_016,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),6109,113,6239,"0,0181118769",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,85","15,42"
"low bq, low freq, many artifacts, many samples",UPN2_017,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),4287,75,4379,"0,017127198",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,14","15,28"
"low bq, low freq, many artifacts, many samples",UPN2_018,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),6250,105,6372,"0,0164783427",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,94","15,81"
"low bq, low freq, many artifacts, many samples",UPN2_019,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),7591,139,7742,"0,017954017",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,11","15,78"
"low bq, low freq, many artifacts, many samples",UPN2_020,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),5876,107,5987,"0,0178720561",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,95","15,61"
"low bq, low freq, many artifacts, many samples",UPN2_021,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),7394,139,7546,"0,0184203552",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,32,"16,53"
"low bq, low freq, many artifacts, many samples",UPN2_002,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),18618,261,18934,"0,0137847259",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,48","16,79"
"low bq, low freq, many artifacts, many samples",UPN2_003,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),3652,47,3706,"0,0126821371",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,56","15,51"
"low bq, low freq, many artifacts, many samples",UPN2_022,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),17797,326,18159,"0,0179525304",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,92","16,04"
"low bq, low freq, many artifacts, many samples",UPN2_023,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),10303,203,10538,"0,0192636174",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,98","15,95"
"low bq, low freq, many artifacts, many samples",UPN2_024,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),4677,86,4774,"0,0180142438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,07","15,66"
"low bq, low freq, many artifacts, many samples",UPN2_025,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),21155,394,21593,"0,018246654",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,92","15,56"
"low bq, low freq, many artifacts, many samples",UPN2_026,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),21613,350,22000,"0,0159090909",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,27","15,65"
"low bq, low freq, many artifacts, many samples",UPN2_027,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),12274,221,12520,"0,0176517572",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,06","16,35"
"low bq, many samples",UPN2_042,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),31565,801,32435,"0,0246955449",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,78","16,08"
"low bq, low freq, many artifacts, many samples",UPN2_028,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),8906,136,9061,"0,0150093809",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,16","16,4"
"low bq, many samples",UPN2_043,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),21376,612,22041,"0,0277664353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,78","16,13"
"low bq, many samples",UPN2_044,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),7098,183,7291,"0,0250994377",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,32,"16,66"
"low bq, low freq, many artifacts, many samples",UPN2_029,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),10947,186,11171,"0,0166502551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,97","15,52"
"low bq, low freq, many artifacts, many samples",UPN2_030,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),10542,157,10730,"0,0146318733",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,99","15,78"
"low bq, low freq, many artifacts, many samples",UPN2_031,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),12218,212,12449,"0,0170294803",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,88","15,81"
"low bq, low freq, many artifacts, many samples",UPN2_005,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),5101,80,5198,"0,0153905348",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,4","17,26"
"low bq, many samples",UPN2_045,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),13515,349,13901,"0,0251061075",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,86","15,95"
"low bq, low freq, many artifacts, many samples",UPN2_032,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),7608,131,7749,"0,0169054071",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,99","16,13"
"low bq, many samples",UPN2_046,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),12712,306,13037,"0,0234716576",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,82","15,95"
"low bq, low freq, many artifacts, many samples",UPN2_033,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),7113,134,7261,"0,0184547583",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,74","16,03"
"low bq, low freq, many artifacts, many samples",UPN2_034,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),2984,51,3044,"0,0167542707",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,94","16,18"
"low bq, many samples",UPN2_047,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),17448,455,17957,"0,0253383082",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,8","15,17"
"low bq, many samples",UPN2_048,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),5685,139,5847,"0,023772875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,8","16,21"
"low bq, low freq, many artifacts, many samples",UPN2_035,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),24726,403,25191,"0,015997777",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,97",15
"low bq, low freq, many artifacts, many samples",UPN2_036,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),16545,265,16858,"0,0157195397",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,93","15,46"
"low bq, low freq, many artifacts, many samples",UPN2_006,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),18772,213,19021,"0,0111981494",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,43","15,65"
"low bq, many samples",UPN2_049,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),13317,350,13687,"0,0255717104",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,94","15,51"
"low bq, low freq, many artifacts, many samples",UPN2_050,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),14287,312,14641,"0,0213100198",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,08","15,8"
"low bq, low freq, many artifacts, many samples",UPN2_037,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),26213,439,26727,"0,0164253377",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,18","15,4"
"low bq, low freq, many artifacts, many samples",UPN2_051,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),12459,263,12751,"0,0206258333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,91","15,71"
"low bq, many samples",UPN2_052,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),22711,528,23286,"0,0226745684",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,02","16,1"
"low bq, low freq, many artifacts, many samples",UPN2_038,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),16283,256,16567,"0,0154524054",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,06","15,49"
"low bq, low freq, many artifacts, many samples",UPN2_039,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),18346,297,18708,"0,0158755613",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,17","16,52"
"low bq, many samples",UPN2_053,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),29886,697,30695,"0,0227072813",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,06","15,95"
"low bq, low freq, many artifacts, many samples",UPN2_054,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),10354,225,10632,"0,0211625282",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,05","16,71"
"low bq, low freq, many artifacts, many samples",UPN2_007,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),21719,308,22063,"0,0139600236",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,27","15,9"
"low bq, low freq, many artifacts, many samples",UPN2_008,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),28350,418,28821,"0,0145033136",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,35","15,99"
"low bq, low freq, many artifacts, many samples",UPN2_009,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),45349,588,46042,"0,0127709483",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,33","15,77"
"low bq, low freq, many artifacts, many samples",UPN2_010,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),31684,405,32144,"0,012599552",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,37","15,66"
"low bq, low freq, many artifacts, many samples",UPN2_011,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),37108,527,37752,"0,0139595253",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,23","15,94"
"low bq, many samples",UPN2_055,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),31344,720,32160,"0,0223880597",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,98","15,74"
"low bq, many samples",UPN2_056,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),6929,186,7129,"0,0260906158",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,04","15,84"
"low bq, many samples",UPN2_057,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),14959,361,15354,"0,0235117885",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,77","15,27"
"low bq, many samples",UPN2_058,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),15827,383,16259,"0,0235561843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,72","15,81"
"low bq, low freq, many artifacts, many samples",UPN2_012,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),10735,161,10924,"0,0147381911",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,3","15,8"
"low bq, low freq, many artifacts, many samples",UPN2_060,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),2713,38,2760,"0,0137681159",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,15",14
"low bq, low freq, many artifacts, many samples",UPN2_040,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),24451,435,24950,"0,0174348697",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,98","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_013,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),5087,84,5182,"0,0162099575",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"32,2","17,39"
"low bq, low freq, many artifacts, many samples",UPN2_061,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),6028,101,6141,"0,0164468328",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,35","15,77"
"low bq, low freq, many artifacts, many samples",UPN2_062,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),4836,69,4926,"0,0140073082",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,34","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_063,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),3488,53,3551,"0,0149253731",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,22","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_064,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),3442,66,3518,"0,0187606595",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,28","15,17"
"low bq, low freq, many artifacts, many samples",UPN2_068,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),2590,41,2634,"0,0155656796",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,33","15,46"
"low bq, low freq, many artifacts, many samples",UPN2_069,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),1776,30,1813,"0,0165471594",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,24","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_070,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),2754,41,2806,"0,0146115467",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,35","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_071,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),4552,78,4639,"0,0168139685",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,08","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_072,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),5737,123,5876,"0,0209326072",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,28","14,77"
"low bq, low freq, many artifacts, many samples",UPN2_073,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),1502,24,1533,"0,0156555773",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,37","15,75"
"low bq, low freq, many artifacts, many samples",UPN2_075,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),4244,79,4328,"0,0182532348",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,09","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_076,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),2493,43,2539,"0,0169358015",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,37","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_077,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),1711,33,1748,"0,0188787185",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,24","14,94"
"low bq, low freq, many artifacts, many samples",UPN2_078,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),3422,64,3493,"0,018322359",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,36","15,34"
"low bq, low freq, many artifacts, many samples",UPN2_079,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),3421,61,3489,"0,0174835196",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,41","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_080,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),4301,80,4386,"0,0182398541",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,35","15,7"
"low bq, low freq, many artifacts, many samples",UPN2_081,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),5714,96,5826,"0,0164778579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,08","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_082,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),2357,46,2406,"0,0191188695",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,19","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_083,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),2095,41,2137,"0,0191857745",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,35","14,17"
"low bq, low freq, many artifacts, many samples",UPN2_084,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),2597,39,2647,"0,0147336607",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,32","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_085,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),1075,22,1101,"0,0199818347",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,25",14
"low bq, low freq, many artifacts, many samples",UPN2_087,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),1551,29,1581,"0,018342821",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,14",14
"low bq, low freq, many artifacts",UPN2_088,X,15840946,A,T,stop_gained(HIGH|NONSENSE|Aga/Tga|p.Arg344*/c.1030A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),2209,36,2246,"0,0160284951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"31,25","15,22"
"low freq, many artifacts",UPN2_073,X,15840949,G,T,missense_variant(MODERATE|MISSENSE|Gac/Tac|p.Asp345Tyr/c.1033G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),1511,22,1534,"0,0143415906",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-5,93",Deleterious,"0,001",Damaging,"31,32","30,23"
"low freq, neutral effect",UPN2_041,X,15840959,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu348Ser/c.1043T>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),410,86,501,"0,1716566866",0,1,0,1,1,1,0,1,5,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,"0,114",Tolerated,"33,26","31,42"
"low bq, low freq, many artifacts",UPN2_060,X,15840959,T,C,missense_variant(MODERATE|MISSENSE|tTg/tCg|p.Leu348Ser/c.1043T>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2739,29,2788,"0,0104017217",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,91",Neutral,"0,114",Tolerated,"32,7","28,79"
"low bq, low freq, many artifacts",UPN2_044,X,15840991,A,T,stop_gained(HIGH|NONSENSE|Aag/Tag|p.Lys359*/c.1075A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),3591,41,3643,"0,0112544606",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"33,96","23,05"
"low bq, low freq, many artifacts, many samples",UPN2_042,X,15840995,A,T,missense_variant(MODERATE|MISSENSE|aAc/aTc|p.Asn360Ile/c.1079A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),15933,183,16190,"0,0113032736",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,44",Deleterious,2,Damaging,"33,87","16,65"
"low bq, low freq, many artifacts, many samples",UPN2_046,X,15840995,A,T,missense_variant(MODERATE|MISSENSE|aAc/aTc|p.Asn360Ile/c.1079A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),6412,78,6506,"0,0119889333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,44",Deleterious,2,Damaging,"33,82","17,64"
"low bq, low freq, many artifacts, many samples",UPN2_057,X,15840995,A,T,missense_variant(MODERATE|MISSENSE|aAc/aTc|p.Asn360Ile/c.1079A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),7559,78,7664,"0,010177453",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,44",Deleterious,2,Damaging,"33,78","17,58"
"low bq, low freq, many artifacts",UPN2_058,X,15840995,A,T,missense_variant(MODERATE|MISSENSE|aAc/aTc|p.Asn360Ile/c.1079A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),8010,98,8126,"0,0120600541",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,44",Deleterious,2,Damaging,"33,89","18,53"
"low bq, low freq, many artifacts, many samples",UPN2_043,X,15841001,A,T,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu362Val/c.1085A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),10852,117,10999,"0,0106373307",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,99,Tolerated,"33,37","18,4"
"low bq, low freq, many artifacts, many samples",UPN2_051,X,15841001,A,T,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu362Val/c.1085A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),6250,74,6351,"0,0116517084",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,99,Tolerated,"33,4","20,18"
"low bq, low freq, many artifacts, many samples",UPN2_052,X,15841001,A,T,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu362Val/c.1085A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),11455,128,11630,"0,0110060189",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,99,Tolerated,"33,5","20,36"
"low bq, low freq, many artifacts, many samples",UPN2_055,X,15841001,A,T,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu362Val/c.1085A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),15869,168,16080,"0,0104477612",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,99,Tolerated,"33,36","19,37"
"low bq, low freq, many artifacts",UPN2_058,X,15841001,A,T,missense_variant(MODERATE|MISSENSE|gAa/gTa|p.Glu362Val/c.1085A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),8013,88,8126,"0,0108294364",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,86",Deleterious,99,Tolerated,"33,28","18,53"
"low bq, low freq, many artifacts, many samples",UPN2_017,X,15841002,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu362Asp/c.1086A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),2158,23,2189,"0,0105070809",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,261,Tolerated,"32,71","16,09"
"low bq, low freq, many artifacts, many samples",UPN2_042,X,15841002,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu362Asp/c.1086A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),15911,208,16193,"0,0128450565",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,261,Tolerated,"31,77","17,11"
"low bq, low freq, many artifacts, many samples",UPN2_043,X,15841002,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu362Asp/c.1086A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),10780,168,10999,"0,0152741158",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,261,Tolerated,"31,79","16,35"
"low bq, low freq, many artifacts, many samples",UPN2_044,X,15841002,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu362Asp/c.1086A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),3594,40,3649,"0,0109619074",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,261,Tolerated,"31,79","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_045,X,15841002,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu362Asp/c.1086A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),6790,116,6948,"0,0166954519",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,261,Tolerated,"31,69","16,14"
"low bq, low freq, many artifacts, many samples",UPN2_046,X,15841002,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu362Asp/c.1086A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),6392,91,6509,"0,0139806422",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,261,Tolerated,"31,9","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_047,X,15841002,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu362Asp/c.1086A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),8825,120,8980,"0,013363029",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,261,Tolerated,"31,78","16,12"
"low bq, low freq, many artifacts, many samples",UPN2_048,X,15841002,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu362Asp/c.1086A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),2870,41,2917,"0,0140555365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,261,Tolerated,"31,9","17,22"
"low bq, low freq, many artifacts, many samples",UPN2_049,X,15841002,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu362Asp/c.1086A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),6714,81,6829,"0,0118611803",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,261,Tolerated,"31,77","15,56"
"low bq, low freq, many artifacts, many samples",UPN2_050,X,15841002,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu362Asp/c.1086A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),7214,83,7332,"0,01132024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,261,Tolerated,"31,84","16,27"
"low bq, low freq, many artifacts, many samples",UPN2_051,X,15841002,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu362Asp/c.1086A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),6241,83,6351,"0,0130688081",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,261,Tolerated,"32,01","15,93"
"low bq, low freq, many artifacts, many samples",UPN2_052,X,15841002,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu362Asp/c.1086A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),11443,151,11630,"0,0129836629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,261,Tolerated,"31,81","15,4"
"low bq, low freq, many artifacts, many samples",UPN2_053,X,15841002,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu362Asp/c.1086A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),15081,179,15337,"0,0116711221",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,261,Tolerated,"31,87","16,99"
"low bq, low freq, many artifacts, many samples",UPN2_054,X,15841002,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu362Asp/c.1086A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),5207,57,5296,"0,0107628399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,261,Tolerated,"31,78","16,65"
"low bq, low freq, many artifacts, many samples",UPN2_055,X,15841002,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu362Asp/c.1086A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),15795,208,16082,"0,0129337147",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,261,Tolerated,"31,85","15,95"
"low bq, low freq, many artifacts, many samples",UPN2_056,X,15841002,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu362Asp/c.1086A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),3484,53,3561,"0,0148834597",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,261,Tolerated,"31,75","17,08"
"low bq, low freq, many artifacts, many samples",UPN2_057,X,15841002,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu362Asp/c.1086A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),7484,125,7664,"0,0163100209",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,261,Tolerated,"31,65","17,07"
"low bq, low freq, many artifacts, many samples",UPN2_058,X,15841002,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu362Asp/c.1086A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),7988,110,8126,"0,0135367955",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,261,Tolerated,"31,73","16,44"
"low bq, low freq, many artifacts",UPN2_013,X,15841002,A,T,missense_variant(MODERATE|MISSENSE|gaA/gaT|p.Glu362Asp/c.1086A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),2543,28,2588,"0,0108191654",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,07",Neutral,261,Tolerated,"32,27","16,14"
"low bq, low freq, many artifacts, many samples",UPN2_020,X,15841003,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg363Trp/c.1087A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),2950,30,2993,"0,0100233879",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,58",Deleterious,3,Damaging,"33,03","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_044,X,15841003,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg363Trp/c.1087A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),3588,40,3649,"0,0109619074",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,58",Deleterious,3,Damaging,"32,38","17,1"
"low bq, low freq, many artifacts, many samples",UPN2_045,X,15841003,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg363Trp/c.1087A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),6831,77,6951,"0,0110775428",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,58",Deleterious,3,Damaging,"32,35","16,57"
"low bq, low freq, many artifacts, many samples",UPN2_055,X,15841003,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg363Trp/c.1087A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),15851,164,16082,"0,0101977366",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,58",Deleterious,3,Damaging,"32,38","15,79"
"low bq, low freq, many artifacts, many samples",UPN2_056,X,15841003,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg363Trp/c.1087A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),3517,36,3561,"0,0101095198",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,58",Deleterious,3,Damaging,"32,16","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_057,X,15841003,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg363Trp/c.1087A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),7539,83,7665,"0,010828441",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,58",Deleterious,3,Damaging,"32,29","16,66"
"low bq, low freq, many artifacts",UPN2_013,X,15841003,A,T,missense_variant(MODERATE|MISSENSE|Agg/Tgg|p.Arg363Trp/c.1087A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),2547,26,2588,"0,0100463679",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,58",Deleterious,3,Damaging,"32,59","15,62"
"low freq, many artifacts",UPN2_048,X,15841017,G,T,missense_variant(MODERATE|MISSENSE|atG/atT|p.Met367Ile/c.1101G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),2871,30,2922,"0,0102669405",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,08",Neutral,421,Tolerated,"34,3","29,4"
"low freq, many artifacts",UPN2_034,X,15841038,C,G,stop_gained(HIGH|NONSENSE|taC/taG|p.Tyr374*/c.1122C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),1503,20,1525,"0,0131147541",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,76","31,3"
"low freq, many artifacts",UPN2_069,X,15841048,CG,C,frameshift_variant(HIGH||gga/|p.Gly379fs/c.1136delG|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C|INFO_REALIGN_3_PRIME),2184,29,2216,"0,0130866426",0,0,0,1,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,86",NA
"low freq, many artifacts",UPN2_044,X,15841067,G,T,missense_variant(MODERATE|MISSENSE|aGt/aTt|p.Ser384Ile/c.1151G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),4532,56,4604,"0,0121633362",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,93",Deleterious,32,Damaging,"35,14","31,62"
"low bq, low freq, many artifacts, many samples",UPN2_059,X,15841073,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp386Ala/c.1157A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3061,47,3126,"0,0150351887",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,63",Deleterious,212,Tolerated,"28,65","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_066,X,15841073,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp386Ala/c.1157A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1784,20,1815,"0,0110192837",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,63",Deleterious,212,Tolerated,"28,25",14
"low bq, low freq, many artifacts, many samples",UPN2_067,X,15841073,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp386Ala/c.1157A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2451,28,2491,"0,0112404657",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,63",Deleterious,212,Tolerated,"28,34","14,46"
"low bq, low freq, many artifacts",UPN2_068,X,15841073,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp386Ala/c.1157A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3550,40,3609,"0,0110834026",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,63",Deleterious,212,Tolerated,"30,18","15,65"
many samples,UPN2_001,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4152,345,4505,"0,076581576",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,31","31,5"
many samples,UPN2_014,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),5987,309,6316,"0,0489233692",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,68","31,47"
many samples,UPN2_015,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),8377,295,8702,"0,0339002528",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,8","31,17"
many samples,UPN2_016,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4069,184,4260,"0,0431924883",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,62","31,18"
"many samples, low freq, no database",UPN2_017,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2662,142,2811,"0,0505158307",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,"0,025",Damaging,"32,51","31,52"
"many samples, low freq, no database",UPN2_018,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4213,199,4428,"0,0449412827",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,"0,025",Damaging,"32,77","31,52"
many samples,UPN2_019,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4979,250,5233,"0,0477737436",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,73","31,61"
many samples,UPN2_020,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3435,205,3649,"0,0561797753",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,43","31,67"
"many samples, low freq, no database",UPN2_021,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4684,285,4988,"0,0571371291",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,"0,025",Damaging,"32,7","31,57"
many samples,UPN2_002,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),9959,805,10789,"0,0746130318",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,19","31,5"
many samples,UPN2_003,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1985,147,2144,"0,0685634328",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,28","31,65"
many samples,UPN2_022,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),11956,509,12500,"0,04072",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,79","31,48"
many samples,UPN2_023,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),6538,295,6839,"0,0431349613",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,59","31,52"
many samples,UPN2_024,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2951,127,3086,"0,0411535969",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,52","31,63"
many samples,UPN2_025,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),14500,571,15106,"0,0377995498",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,73","31,47"
"many samples, low freq, no database",UPN2_026,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),13681,674,14387,"0,0468478488",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,"0,025",Damaging,"32,64","31,51"
many samples,UPN2_004,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),566,41,607,"0,0675453048",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,75","31,56"
"many samples, low freq, no database",UPN2_027,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),7809,424,8262,"0,0513192931",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,"0,025",Damaging,"32,65","31,57"
"low freq, many artifacts, many samples",UPN2_042,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),20293,415,20774,"0,0199768942",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,29","31,23"
"many samples, low freq, no database",UPN2_028,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),5836,308,6157,"0,0500243625",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,"0,025",Damaging,"32,76","31,56"
"many samples, low freq, no database",UPN2_043,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),13153,328,13525,"0,0242513863",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,"0,025",Damaging,"32,26","31,14"
"many samples, low freq, no database",UPN2_044,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4402,141,4558,"0,0309346204",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,"0,025",Damaging,"32,24","31,1"
"many samples, low freq, no database",UPN2_029,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),6436,387,6850,"0,0564963504",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,"0,025",Damaging,"32,56","31,31"
many samples,UPN2_030,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),6919,344,7280,"0,0472527473",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,69","31,65"
"many samples, low freq, no database",UPN2_031,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),8279,297,8606,"0,0345108064",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,"0,025",Damaging,"32,75","31,39"
many samples,UPN2_005,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2724,242,2981,"0,0811808118",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,21","31,57"
"low freq, many artifacts, many samples",UPN2_045,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),7873,114,8018,"0,0142180095",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,07","31,75"
many samples,UPN2_032,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4733,213,4963,"0,0429175902",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,58","31,37"
many samples,UPN2_046,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),8325,295,8639,"0,0341474708",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,39","31,37"
many samples,UPN2_033,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4704,184,4897,"0,0375740249",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,67","31,3"
many samples,UPN2_034,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2006,66,2079,"0,0317460317",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,78","31,48"
"low freq, many artifacts, many samples",UPN2_047,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),11391,243,11678,"0,0208083576",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,34","31,09"
"many samples, low freq, no database",UPN2_048,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),6203,108,6327,"0,0170697013",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,"0,025",Damaging,"33,08",31
"many samples, low freq, no database",UPN2_035,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),16167,891,17094,"0,0521235521",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,"0,025",Damaging,"32,74","31,47"
many samples,UPN2_036,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),10085,621,10723,"0,0579128975",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,59","31,58"
many samples,UPN2_006,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),10931,1011,11979,"0,084397696",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,46","31,28"
many samples,UPN2_049,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),8250,222,8484,"0,0261669024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,23","31,08"
many samples,UPN2_037,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),16367,792,17200,"0,0460465116",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,59","31,45"
"low freq, many artifacts, many samples",UPN2_051,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),8211,121,8357,"0,01447888",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,39","30,54"
many samples,UPN2_038,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),10506,521,11042,"0,0471834813",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,66","31,42"
"many samples, low freq, no database",UPN2_039,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),11977,626,12639,"0,0495292349",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,"0,025",Damaging,"32,74","31,46"
"many samples, low freq, no database",UPN2_053,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),18729,509,19302,"0,0263703243",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,"0,025",Damaging,"32,31","31,23"
"low freq, many artifacts, many samples",UPN2_054,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),6605,93,6710,"0,0138599106",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,34","31,38"
"many samples, low freq, no database",UPN2_007,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),12087,895,13034,"0,0686665644",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,"0,025",Damaging,"32,36","31,46"
"many samples, low freq, no database",UPN2_008,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),16123,1057,17240,"0,0613109049",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,"0,025",Damaging,"32,36","31,53"
"many samples, low freq, no database",UPN2_009,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),25719,1451,27252,"0,0532437986",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,"0,025",Damaging,"32,31","31,49"
"many samples, low freq, no database",UPN2_010,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),18175,1169,19394,"0,0602763741",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,"0,025",Damaging,"32,31","31,41"
many samples,UPN2_011,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),20179,1528,21753,"0,0702431848",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,23","31,51"
"many samples, low freq, no database",UPN2_055,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),19821,397,20285,"0,0195711117",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,"0,025",Damaging,"32,3","30,81"
"low freq, many artifacts, many samples",UPN2_056,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4839,88,4950,"0,0177777778",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,49","30,6"
many samples,UPN2_057,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),9102,256,9418,"0,0271819919",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,21","31,3"
"many samples, low freq, no database",UPN2_058,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),9887,387,10301,"0,037569168",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,"0,025",Damaging,"32,31","30,97"
many samples,UPN2_012,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),5986,437,6444,"0,0678150217",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,32","31,46"
many samples,UPN2_060,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2079,112,2196,"0,0510018215",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,6","31,08"
many samples,UPN2_040,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),15049,848,15926,"0,053246264",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,55","31,53"
many samples,UPN2_013,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2884,189,3082,"0,0613238157",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,25","31,48"
"low freq, many artifacts, many samples",UPN2_091,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4452,55,4520,"0,0121681416",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,46","31,02"
many samples,UPN2_061,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4636,239,4889,"0,0488852526",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,72","30,96"
"many samples, low freq, no database",UPN2_062,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3043,225,3275,"0,0687022901",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,"0,025",Damaging,"32,4","31,53"
many samples,UPN2_063,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2503,167,2673,"0,062476618",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,67","31,17"
many samples,UPN2_064,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),5249,149,5412,"0,0275314117",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"33,57","30,91"
"many samples, low freq, no database",UPN2_068,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3449,110,3573,"0,030786454",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,"0,025",Damaging,"33,43","30,95"
many samples,UPN2_069,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2150,80,2235,"0,0357941834",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"33,38","30,09"
many samples,UPN2_070,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2817,103,2927,"0,0351896139",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"33,2","30,91"
many samples,UPN2_071,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2814,173,2997,"0,0577243911",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,25","31,42"
"many samples, low freq, no database",UPN2_072,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3745,270,4029,"0,0670141474",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,"0,025",Damaging,"32,48","31,02"
many samples,UPN2_073,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1963,47,2013,"0,0233482365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"33,25","30,47"
"many samples, low freq, no database",UPN2_074,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2202,50,2260,"0,0221238938",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,"0,025",Damaging,"33,68","30,2"
"many samples, low freq, no database",UPN2_075,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3106,174,3284,"0,0529841657",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,"0,025",Damaging,"32,76","31,09"
many samples,UPN2_076,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2283,121,2407,"0,0502700457",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"33,07",31
many samples,UPN2_077,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1985,65,2055,"0,0316301703",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"33,34","30,38"
many samples,UPN2_078,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2612,153,2770,"0,055234657",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,77","31,2"
many samples,UPN2_079,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2666,147,2817,"0,0521831736",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,85","31,36"
many samples,UPN2_080,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2775,203,2984,"0,0680294906",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,53","31,25"
many samples,UPN2_081,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4954,211,5177,"0,0407571953",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,96","30,99"
"many samples, low freq, no database",UPN2_082,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4204,91,4311,"0,0211087915",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,"0,025",Damaging,"33,68","29,38"
many samples,UPN2_083,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2138,98,2241,"0,0437304775",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"33,2","30,86"
many samples,UPN2_084,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2888,94,2987,"0,031469702",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"33,15","30,85"
"low freq, many artifacts, many samples",UPN2_085,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1950,38,1991,"0,0190858865",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"33,72","31,05"
many samples,UPN2_087,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2219,66,2292,"0,0287958115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"33,42","31,45"
"many samples, low freq, no database",UPN2_088,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3511,109,3630,"0,0300275482",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,"0,025",Damaging,"33,6","31,11"
"low freq, many artifacts",UPN2_098,X,15841096,G,C,missense_variant(MODERATE|MISSENSE|Gaa/Caa|p.Glu394Gln/c.1180G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4940,50,4994,"0,0100120144",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,58",Neutral,25,Damaging,"32,38","31,56"
"many samples, low freq, no database",UPN2_002,X,15841097,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu394Gly/c.1181A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),1473,31,1510,"0,0205298013",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,01",Deleterious,"0,003",Damaging,34,"31,61"
"low freq, many artifacts, many samples",UPN2_022,X,15841097,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu394Gly/c.1181A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),3550,40,3599,"0,0111141984",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,01",Deleterious,3,Damaging,"35,06","30,08"
"many samples, low freq, no database",UPN2_026,X,15841097,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu394Gly/c.1181A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),3530,44,3586,"0,0122699387",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,01",Deleterious,"0,003",Damaging,"34,88","31,2"
"many samples, low freq, no database",UPN2_089,X,15841097,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu394Gly/c.1181A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),2124,28,2158,"0,0129749768",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,01",Deleterious,"0,003",Damaging,"34,73","31,29"
"many samples, low freq, no database",UPN2_042,X,15841097,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu394Gly/c.1181A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),4704,61,4783,"0,012753502",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,01",Deleterious,"0,003",Damaging,"34,17","32,62"
"many samples, low freq, no database",UPN2_028,X,15841097,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu394Gly/c.1181A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),1692,20,1716,"0,0116550117",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,01",Deleterious,"0,003",Damaging,"34,68","29,2"
"many samples, low freq, no database",UPN2_043,X,15841097,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu394Gly/c.1181A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),2675,36,2721,"0,01323043",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,01",Deleterious,"0,003",Damaging,"34,09","32,19"
"low freq, many artifacts, many samples",UPN2_029,X,15841097,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu394Gly/c.1181A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),1377,23,1405,"0,0163701068",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,01",Deleterious,3,Damaging,"34,97","30,61"
"many samples, low freq, no database",UPN2_031,X,15841097,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu394Gly/c.1181A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),2448,25,2484,"0,0100644122",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,01",Deleterious,"0,003",Damaging,"34,99","32,28"
"many samples, low freq, no database",UPN2_045,X,15841097,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu394Gly/c.1181A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),1122,21,1148,"0,0182926829",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,01",Deleterious,"0,003",Damaging,"34,06","30,86"
"many samples, low freq, no database",UPN2_046,X,15841097,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu394Gly/c.1181A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),2177,25,2212,"0,0113019892",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,01",Deleterious,"0,003",Damaging,"33,92","32,76"
"many samples, low freq, no database",UPN2_047,X,15841097,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu394Gly/c.1181A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),2812,37,2860,"0,0129370629",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,01",Deleterious,"0,003",Damaging,"34,18","32,59"
"low freq, many artifacts, many samples",UPN2_035,X,15841097,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu394Gly/c.1181A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),4713,48,4774,"0,0100544617",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,01",Deleterious,3,Damaging,"34,85","31,73"
"many samples, low freq, no database",UPN2_036,X,15841097,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu394Gly/c.1181A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),2418,31,2455,"0,0126272912",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,01",Deleterious,"0,003",Damaging,"34,68","30,9"
"many samples, low freq, no database",UPN2_006,X,15841097,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu394Gly/c.1181A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),2563,73,2664,"0,0274024024",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,01",Deleterious,"0,003",Damaging,"34,27","31,97"
"many samples, low freq, no database",UPN2_050,X,15841097,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu394Gly/c.1181A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),1498,49,1552,"0,0315721649",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,01",Deleterious,"0,003",Damaging,"33,86","31,55"
"many samples, low freq, no database",UPN2_037,X,15841097,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu394Gly/c.1181A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),3985,46,4052,"0,0113524186",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,01",Deleterious,"0,003",Damaging,"34,66","33,39"
"many samples, low freq, no database",UPN2_038,X,15841097,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu394Gly/c.1181A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),2903,37,2947,"0,0125551408",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,01",Deleterious,"0,003",Damaging,"34,85","30,68"
"many samples, low freq, no database",UPN2_053,X,15841097,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu394Gly/c.1181A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),4148,58,4220,"0,0137440758",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,01",Deleterious,"0,003",Damaging,"33,73","32,17"
"many samples, low freq, no database",UPN2_007,X,15841097,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu394Gly/c.1181A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),2149,26,2181,"0,0119211371",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,01",Deleterious,"0,003",Damaging,"34,75","30,54"
"many samples, low freq, no database",UPN2_008,X,15841097,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu394Gly/c.1181A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),3022,35,3064,"0,0114229765",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,01",Deleterious,"0,003",Damaging,"34,44","31,54"
"many samples, low freq, no database",UPN2_009,X,15841097,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu394Gly/c.1181A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),4558,89,4661,"0,0190946149",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,01",Deleterious,"0,003",Damaging,"34,65","30,85"
"many samples, low freq, no database",UPN2_010,X,15841097,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu394Gly/c.1181A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),3500,47,3554,"0,0132245357",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,01",Deleterious,"0,003",Damaging,"34,42","32,62"
"many samples, low freq, no database",UPN2_011,X,15841097,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu394Gly/c.1181A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),3197,43,3253,"0,0132185675",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,01",Deleterious,"0,003",Damaging,"34,68","31,47"
"many samples, low freq, no database",UPN2_055,X,15841097,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu394Gly/c.1181A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),4386,67,4467,"0,0149988807",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,01",Deleterious,"0,003",Damaging,"34,01","31,79"
"many samples, low freq, no database",UPN2_090,X,15841097,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu394Gly/c.1181A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),734,33,768,"0,04296875",0,0,0,0,1,1,0,0,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,01",Deleterious,"0,003",Damaging,"34,83","31,12"
"low freq, many artifacts",UPN2_057,X,15841097,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu394Gly/c.1181A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),1854,31,1892,"0,016384778",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,01",Deleterious,3,Damaging,"34,08","30,39"
"many samples, low freq, no database",UPN2_058,X,15841097,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu394Gly/c.1181A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),2303,27,2340,"0,0115384615",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,01",Deleterious,"0,003",Damaging,"34,03","30,85"
"many samples, low freq, no database",UPN2_012,X,15841097,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu394Gly/c.1181A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),985,23,1011,"0,0227497527",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,01",Deleterious,"0,003",Damaging,"34,63","33,17"
"many samples, low freq, no database",UPN2_092,X,15841097,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu394Gly/c.1181A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),1089,38,1131,"0,0335985853",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,01",Deleterious,"0,003",Damaging,"34,58","31,39"
"many samples, low freq, no database",UPN2_072,X,15841097,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu394Gly/c.1181A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),1111,23,1142,"0,0201401051",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,01",Deleterious,"0,003",Damaging,"33,72","32,43"
"many samples, low freq, no database",UPN2_095,X,15841097,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu394Gly/c.1181A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),2006,25,2036,"0,0122789784",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,01",Deleterious,"0,003",Damaging,"34,7","31,2"
"many samples, low freq, no database",UPN2_096,X,15841097,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu394Gly/c.1181A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),1547,22,1572,"0,0139949109",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,01",Deleterious,"0,003",Damaging,"34,75","31,09"
"many samples, low freq, no database",UPN2_097,X,15841097,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu394Gly/c.1181A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),1761,23,1787,"0,0128707331",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,01",Deleterious,"0,003",Damaging,"34,48","30,78"
"many samples, low freq, no database",UPN2_100,X,15841097,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu394Gly/c.1181A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),1964,24,1995,"0,0120300752",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,01",Deleterious,"0,003",Damaging,"34,76","31,75"
"many samples, low freq, no database",UPN2_103,X,15841097,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu394Gly/c.1181A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),2344,33,2380,"0,0138655462",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,01",Deleterious,"0,003",Damaging,"34,37","29,76"
"many samples, low freq, no database",UPN2_110,X,15841097,A,G,missense_variant(MODERATE|MISSENSE|gAa/gGa|p.Glu394Gly/c.1181A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),1123,20,1144,"0,0174825175",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,01",Deleterious,"0,003",Damaging,"34,64","30,75"
"low bq, low freq, many artifacts, many samples",UPN2_052,X,15841099,T,A,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser395Thr/c.1183T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2527,26,2562,"0,0101483216",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,0,NO,NO,"-1,2",Neutral,36,Damaging,"33,88","16,38"
"low bq, low freq, many artifacts, many samples",UPN2_058,X,15841099,T,A,missense_variant(MODERATE|MISSENSE|Tcc/Acc|p.Ser395Thr/c.1183T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2284,27,2321,"0,0116329168",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,0,NO,NO,"-1,2",Neutral,36,Damaging,"34,22","16,96"
"many samples, low freq, neutral effect",UPN2_015,X,15841111,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser399Gly/c.1195A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),2527,27,2556,"0,0105633803",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,"0,326",Tolerated,"34,46","34,89"
"many samples, low freq, neutral effect",UPN2_027,X,15841111,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser399Gly/c.1195A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),2091,23,2123,"0,0108337259",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,"0,326",Tolerated,"34,3","34,48"
"many samples, low freq, neutral effect",UPN2_046,X,15841111,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser399Gly/c.1195A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),2169,26,2199,"0,0118235562",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,"0,326",Tolerated,"33,47",34
"many samples, low freq, neutral effect",UPN2_048,X,15841111,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser399Gly/c.1195A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),3395,48,3452,"0,0139049826",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,"0,326",Tolerated,"33,56","33,44"
"low freq, many artifacts, many samples",UPN2_086,X,15841111,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser399Gly/c.1195A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),2454,25,2489,"0,0100441945",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,326,Tolerated,"33,1","31,88"
"many samples, low freq, neutral effect",UPN2_095,X,15841111,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser399Gly/c.1195A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),1998,23,2023,"0,0113692536",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,"0,326",Tolerated,"33,99","34,78"
"many samples, low freq, neutral effect",UPN2_107,X,15841111,A,G,missense_variant(MODERATE|MISSENSE|Agt/Ggt|p.Ser399Gly/c.1195A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),1525,21,1546,"0,0135834411",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,"0,326",Tolerated,"34,2","34,76"
"low bq, low freq, many artifacts, many samples",UPN2_043,X,15841113,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser399Arg/c.1197T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2645,34,2693,"0,0126253249",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,76",Neutral,981,Tolerated,"33,49","17,21"
"low bq, low freq, many artifacts, many samples",UPN2_047,X,15841113,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser399Arg/c.1197T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2776,33,2828,"0,011669024",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,76",Neutral,981,Tolerated,"33,34","16,12"
"low bq, low freq, many artifacts, many samples",UPN2_051,X,15841113,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser399Arg/c.1197T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2060,22,2088,"0,0105363985",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,76",Neutral,981,Tolerated,"33,07","16,64"
"low bq, low freq, many artifacts, many samples",UPN2_052,X,15841113,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser399Arg/c.1197T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2528,26,2561,"0,0101522843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,76",Neutral,981,Tolerated,"33,14","15,88"
"low bq, low freq, many artifacts, many samples",UPN2_053,X,15841113,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser399Arg/c.1197T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4112,46,4171,"0,0110285303",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,76",Neutral,981,Tolerated,33,"15,43"
"low bq, low freq, many artifacts",UPN2_055,X,15841113,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser399Arg/c.1197T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4339,52,4408,"0,0117967332",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"0,76",Neutral,981,Tolerated,"33,18","14,4"
"low freq, many artifacts",UPN2_006,X,15841115,G,A,missense_variant(MODERATE|MISSENSE|aGt/aAt|p.Ser400Asn/c.1199G>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2568,26,2596,"0,0100154083",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,18",Neutral,164,Tolerated,"34,49","28,35"
"low bq, low freq, many artifacts, many samples",UPN2_041,X,15841116,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser400Arg/c.1200T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3200,33,3245,"0,0101694915",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,07",Tolerated,"33,26","17,88"
"low bq, low freq, many artifacts, many samples",UPN2_042,X,15841116,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser400Arg/c.1200T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4669,51,4742,"0,0107549557",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,07",Tolerated,"33,05","19,14"
"low bq, low freq, many artifacts, many samples",UPN2_043,X,15841116,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser400Arg/c.1200T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2654,30,2692,"0,0111441308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,07",Tolerated,"33,11","17,77"
"low bq, low freq, many artifacts, many samples",UPN2_047,X,15841116,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser400Arg/c.1200T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2783,35,2827,"0,0123806155",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,07",Tolerated,"33,2","18,29"
"low bq, low freq, many artifacts, many samples",UPN2_049,X,15841116,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser400Arg/c.1200T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1725,25,1759,"0,0142126208",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,07",Tolerated,"33,16","16,6"
"low bq, low freq, many artifacts, many samples",UPN2_053,X,15841116,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser400Arg/c.1200T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4102,49,4171,"0,0117477823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,07",Tolerated,"33,04","18,02"
"low bq, low freq, many artifacts",UPN2_082,X,15841116,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser400Arg/c.1200T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3083,34,3130,"0,0108626198",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,86",Neutral,"0,07",Tolerated,"32,71","16,59"
"low freq, many artifacts",UPN2_050,X,15841120,C,A,missense_variant(MODERATE|MISSENSE|Cac/Aac|p.His402Asn/c.1204C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1479,23,1505,"0,015282392",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-1,84",Neutral,"0,016",Damaging,"33,78","25,43"
"low freq, many artifacts",UPN2_041,X,15841122,C,A,missense_variant(MODERATE|MISSENSE|caC/caA|p.His402Gln/c.1206C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3202,33,3245,"0,0101694915",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,17,Damaging,"32,93","30,42"
"low freq, many artifacts",UPN2_052,X,15841123,A,G,missense_variant(MODERATE|MISSENSE|Agg/Ggg|p.Arg403Gly/c.1207A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),2522,29,2559,"0,0113325518",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,55",Deleterious,"0,03",Damaging,"33,95","30,86"
"low freq, many artifacts",UPN2_057,X,15841123,A,G,missense_variant(MODERATE|MISSENSE|Agg/Ggg|p.Arg403Gly/c.1207A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),1811,23,1839,"0,0125067972",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,55",Deleterious,"0,03",Damaging,"34,07","33,57"
"low freq, many artifacts",UPN2_093,X,15841123,A,G,missense_variant(MODERATE|MISSENSE|Agg/Ggg|p.Arg403Gly/c.1207A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),1506,22,1531,"0,014369693",0,0,0,0,1,0,0,1,2,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-3,55",Deleterious,"0,03",Damaging,"34,36","35,64"
"low bq, low freq, many artifacts, many samples",UPN2_067,X,15841126,G,C,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly404Arg/c.1210G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2168,24,2203,"0,0108942351",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,26",Neutral,243,Tolerated,"31,75","15,62"
"low bq, low freq, many artifacts, many samples",UPN2_086,X,15841126,G,C,missense_variant(MODERATE|MISSENSE|Ggg/Cgg|p.Gly404Arg/c.1210G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2446,28,2487,"0,0112585444",0,0,0,0,1,0,0,0,1,NO,NO,NO,NA,NA,NO,NO,NO,NO,NO,NO,"-0,26",Neutral,243,Tolerated,"31,65",14
"low bq, low freq, many artifacts, many samples",UPN2_046,X,15841130,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys405Met/c.1214A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),2160,26,2196,"0,0118397086",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,7",Deleterious,4,Damaging,"31,11","14,85"
"low bq, low freq, many artifacts",UPN2_052,X,15841130,A,T,missense_variant(MODERATE|MISSENSE|aAg/aTg|p.Lys405Met/c.1214A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),2515,28,2559,"0,0109417741",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,7",Deleterious,4,Damaging,"30,83","18,11"
"low bq, low freq, many artifacts",UPN2_068,X,15841132,A,C,missense_variant(MODERATE|MISSENSE|Aaa/Caa|p.Lys406Gln/c.1216A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2251,25,2283,"0,0109505037",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,39",Neutral,95,Tolerated,"29,8","14,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_066,X,15841133,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys406Ile/c.1217A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),1596,21,1628,"0,0128992629",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,15",Deleterious,11,Damaging,"25,86","15,9"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_082,X,15841133,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys406Ile/c.1217A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),3033,32,3082,"0,0103828683",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,15",Deleterious,11,Damaging,"26,54","15,94"
"low bq, bad alignment, many samples",UPN2_059,X,15841134,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys406Asn/c.1218A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2570,62,2654,"0,0233609646",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,27,Damaging,23,"14,47"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,X,15841134,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys406Asn/c.1218A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1796,35,1845,"0,0189701897",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,27,Damaging,"22,89","15,03"
"low bq, bad alignment, many samples",UPN2_062,X,15841134,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys406Asn/c.1218A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),807,22,836,"0,0263157895",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,27,Damaging,"22,74",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,X,15841134,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys406Asn/c.1218A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3575,68,3670,"0,0185286104",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,27,Damaging,"23,2","14,53"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_065,X,15841134,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys406Asn/c.1218A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3317,57,3393,"0,0167992927",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,27,Damaging,"23,85","15,12"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_066,X,15841134,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys406Asn/c.1218A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1591,24,1627,"0,0147510756",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,27,Damaging,"23,57","15,62"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_067,X,15841134,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys406Asn/c.1218A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2156,37,2199,"0,0168258299",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,27,Damaging,"23,52","14,19"
"low bq, bad alignment, many samples",UPN2_068,X,15841134,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys406Asn/c.1218A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2215,57,2281,"0,0249890399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,27,Damaging,"22,76","14,86"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_069,X,15841134,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys406Asn/c.1218A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1280,25,1310,"0,0190839695",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,27,Damaging,"22,98","15,16"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_070,X,15841134,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys406Asn/c.1218A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1498,24,1533,"0,0156555773",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,27,Damaging,"22,86",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,X,15841134,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys406Asn/c.1218A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1216,22,1245,"0,0176706827",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,27,Damaging,"23,13","14,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,X,15841134,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys406Asn/c.1218A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1626,24,1659,"0,0144665461",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,27,Damaging,"23,15",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_075,X,15841134,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys406Asn/c.1218A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1135,25,1162,"0,0215146299",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,27,Damaging,"23,32",14
"low bq, bad alignment, many samples",UPN2_076,X,15841134,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys406Asn/c.1218A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1118,31,1156,"0,026816609",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,27,Damaging,"23,26","14,23"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,X,15841134,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys406Asn/c.1218A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1154,21,1187,"0,0176916596",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,27,Damaging,"23,01","14,62"
"low bq, bad alignment, many samples",UPN2_078,X,15841134,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys406Asn/c.1218A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),993,27,1029,"0,0262390671",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,27,Damaging,"22,49","14,26"
"low bq, bad alignment, many samples",UPN2_081,X,15841134,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys406Asn/c.1218A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2233,51,2294,"0,0222319093",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,27,Damaging,"23,81","14,84"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_082,X,15841134,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys406Asn/c.1218A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3017,52,3081,"0,0168776371",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,27,Damaging,"23,59","14,5"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,X,15841134,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys406Asn/c.1218A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1161,23,1193,"0,0192791282",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,27,Damaging,"22,45","14,61"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,X,15841134,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys406Asn/c.1218A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1623,29,1670,"0,0173652695",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,27,Damaging,"23,57","14,24"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_085,X,15841134,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys406Asn/c.1218A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1409,26,1443,"0,018018018",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,27,Damaging,"23,34","14,85"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,X,15841134,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys406Asn/c.1218A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2405,48,2478,"0,01937046",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,27,Damaging,"22,9","14,65"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_087,X,15841134,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys406Asn/c.1218A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1504,22,1533,"0,0143509459",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,27,Damaging,"23,38","14,59"
"low bq, bad alignment, low freq, many artifacts",UPN2_088,X,15841134,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys406Asn/c.1218A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2452,49,2527,"0,0193905817",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,1",Neutral,27,Damaging,"23,29","14,55"
"low bq, low freq, many artifacts",UPN2_053,X,15841135,T,A,missense_variant(MODERATE|MISSENSE|Tct/Act|p.Ser407Thr/c.1219T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4101,47,4166,"0,0112818051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,69",Neutral,56,Tolerated,"32,58","15,98"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_059,X,15841139,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His408Pro/c.1223A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2578,48,2648,"0,0181268882",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,55",Deleterious,16,Damaging,"22,11","15,25"
"low bq, bad alignment, many samples",UPN2_060,X,15841139,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His408Pro/c.1223A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),794,25,828,"0,0301932367",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,55",Deleterious,16,Damaging,"22,15",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,X,15841139,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His408Pro/c.1223A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1794,35,1841,"0,0190114068",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,55",Deleterious,16,Damaging,"22,22","15,4"
"low bq, bad alignment, many samples",UPN2_063,X,15841139,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His408Pro/c.1223A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),926,23,955,"0,0240837696",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,55",Deleterious,16,Damaging,"22,22",14
"low bq, bad alignment, many samples",UPN2_064,X,15841139,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His408Pro/c.1223A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3553,87,3667,"0,0237251159",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,55",Deleterious,16,Damaging,"22,12","14,94"
"low bq, bad alignment, many samples",UPN2_065,X,15841139,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His408Pro/c.1223A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3279,79,3389,"0,0233107111",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,55",Deleterious,16,Damaging,"22,76","15,25"
"low bq, bad alignment, many samples",UPN2_066,X,15841139,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His408Pro/c.1223A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1566,38,1626,"0,0233702337",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,55",Deleterious,16,Damaging,"22,45","14,55"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_067,X,15841139,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His408Pro/c.1223A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2139,40,2196,"0,0182149362",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,55",Deleterious,16,Damaging,"22,8","15,38"
"low bq, bad alignment, many samples",UPN2_068,X,15841139,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His408Pro/c.1223A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2192,53,2276,"0,0232864675",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,55",Deleterious,16,Damaging,"22,09","14,49"
"low bq, bad alignment, many samples",UPN2_069,X,15841139,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His408Pro/c.1223A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1273,30,1308,"0,0229357798",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,55",Deleterious,16,Damaging,"22,54","15,4"
"low bq, bad alignment, many samples",UPN2_070,X,15841139,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His408Pro/c.1223A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1488,35,1533,"0,0228310502",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,55",Deleterious,16,Damaging,22,"14,57"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,X,15841139,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His408Pro/c.1223A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1081,23,1115,"0,0206278027",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,55",Deleterious,16,Damaging,"22,61","14,61"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,X,15841139,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His408Pro/c.1223A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1207,27,1244,"0,0217041801",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,55",Deleterious,16,Damaging,"22,55",14
"low bq, bad alignment, many samples",UPN2_074,X,15841139,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His408Pro/c.1223A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1604,39,1658,"0,023522316",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,55",Deleterious,16,Damaging,"22,42","14,9"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_075,X,15841139,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His408Pro/c.1223A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1123,24,1160,"0,0206896552",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,55",Deleterious,16,Damaging,"22,46",14
"low bq, bad alignment, many samples",UPN2_076,X,15841139,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His408Pro/c.1223A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1113,34,1156,"0,0294117647",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,55",Deleterious,16,Damaging,"21,94","14,85"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,X,15841139,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His408Pro/c.1223A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1149,25,1187,"0,0210614996",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,55",Deleterious,16,Damaging,"22,42",14
"low bq, bad alignment, many samples",UPN2_078,X,15841139,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His408Pro/c.1223A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),996,25,1028,"0,0243190661",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,55",Deleterious,16,Damaging,"22,07",14
"low bq, bad alignment, many samples",UPN2_079,X,15841139,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His408Pro/c.1223A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1069,29,1112,"0,0260791367",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,55",Deleterious,16,Damaging,"22,61",14
"low bq, bad alignment, many samples",UPN2_081,X,15841139,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His408Pro/c.1223A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2212,56,2291,"0,0244434745",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,55",Deleterious,16,Damaging,"22,8",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_082,X,15841139,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His408Pro/c.1223A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2991,65,3077,"0,0211244719",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,55",Deleterious,16,Damaging,"22,32","14,2"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,X,15841139,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His408Pro/c.1223A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1160,22,1192,"0,0184563758",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,55",Deleterious,16,Damaging,"21,26",15
"low bq, bad alignment, many samples",UPN2_084,X,15841139,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His408Pro/c.1223A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1610,42,1667,"0,025194961",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,55",Deleterious,16,Damaging,"21,72","15,05"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_085,X,15841139,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His408Pro/c.1223A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1402,27,1442,"0,0187239945",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,55",Deleterious,16,Damaging,"22,5","15,07"
"low bq, bad alignment, many samples",UPN2_086,X,15841139,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His408Pro/c.1223A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2384,60,2474,"0,0242522231",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,55",Deleterious,16,Damaging,"21,92","14,48"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_087,X,15841139,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His408Pro/c.1223A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1491,30,1531,"0,0195950359",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,55",Deleterious,16,Damaging,"22,45","16,17"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_088,X,15841139,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His408Pro/c.1223A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2451,52,2522,"0,0206185567",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,55",Deleterious,16,Damaging,"22,32","14,35"
"low bq, bad alignment, low freq, many artifacts",UPN2_103,X,15841139,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His408Pro/c.1223A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2297,30,2343,"0,0128040973",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,55",Deleterious,16,Damaging,"22,88","14,73"
"low bq, low freq, many artifacts",UPN2_036,X,15841139,A,G,missense_variant(MODERATE|MISSENSE|cAc/cGc|p.His408Arg/c.1223A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),2388,27,2430,"0,0111111111",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,1",Neutral,"0,198",Tolerated,"26,8","29,96"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_059,X,15841141,A,C,missense_variant(MODERATE|MISSENSE|Aaa/Caa|p.Lys409Gln/c.1225A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2590,36,2646,"0,0136054422",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,25,Damaging,"24,37",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,X,15841141,A,C,missense_variant(MODERATE|MISSENSE|Aaa/Caa|p.Lys409Gln/c.1225A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1809,23,1839,"0,0125067972",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,25,Damaging,"24,2",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_065,X,15841141,A,C,missense_variant(MODERATE|MISSENSE|Aaa/Caa|p.Lys409Gln/c.1225A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3315,48,3387,"0,0141718335",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,25,Damaging,"24,93","14,29"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_066,X,15841141,A,C,missense_variant(MODERATE|MISSENSE|Aaa/Caa|p.Lys409Gln/c.1225A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1579,31,1625,"0,0190769231",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,25,Damaging,"24,15","14,71"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_068,X,15841141,A,C,missense_variant(MODERATE|MISSENSE|Aaa/Caa|p.Lys409Gln/c.1225A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2223,31,2276,"0,0136203866",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,25,Damaging,"23,89","14,23"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,X,15841141,A,C,missense_variant(MODERATE|MISSENSE|Aaa/Caa|p.Lys409Gln/c.1225A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1212,22,1244,"0,0176848875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,25,Damaging,"24,53","14,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,X,15841141,A,C,missense_variant(MODERATE|MISSENSE|Aaa/Caa|p.Lys409Gln/c.1225A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1620,24,1657,"0,0144840072",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,25,Damaging,"24,11","14,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_081,X,15841141,A,C,missense_variant(MODERATE|MISSENSE|Aaa/Caa|p.Lys409Gln/c.1225A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2246,25,2291,"0,0109122654",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,25,Damaging,"24,82","15,52"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_085,X,15841141,A,C,missense_variant(MODERATE|MISSENSE|Aaa/Caa|p.Lys409Gln/c.1225A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1408,23,1442,"0,0159500693",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,25,Damaging,"24,13",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,X,15841141,A,C,missense_variant(MODERATE|MISSENSE|Aaa/Caa|p.Lys409Gln/c.1225A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2425,31,2472,"0,0125404531",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,25,Damaging,"23,87","14,42"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_087,X,15841141,A,C,missense_variant(MODERATE|MISSENSE|Aaa/Caa|p.Lys409Gln/c.1225A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1497,20,1529,"0,0130804447",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,25,Damaging,"24,72","15,05"
"low bq, bad alignment, low freq, many artifacts",UPN2_088,X,15841141,A,C,missense_variant(MODERATE|MISSENSE|Aaa/Caa|p.Lys409Gln/c.1225A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2464,32,2521,"0,0126933756",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,03",Neutral,25,Damaging,"24,22","15,09"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,X,15841142,A,C,missense_variant(MODERATE|MISSENSE|aAa/aCa|p.Lys409Thr/c.1226A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2043,22,2083,"0,0105616899",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,12,Damaging,"26,18","14,59"
"low bq, bad alignment, many samples",UPN2_059,X,15841142,A,C,missense_variant(MODERATE|MISSENSE|aAa/aCa|p.Lys409Thr/c.1226A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2532,92,2646,"0,0347694633",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,12,Damaging,"21,55","14,41"
"low bq, bad alignment, many samples",UPN2_060,X,15841142,A,C,missense_variant(MODERATE|MISSENSE|aAa/aCa|p.Lys409Thr/c.1226A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),798,24,828,"0,0289855072",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,12,Damaging,"21,21","14,29"
"low bq, bad alignment, many samples",UPN2_061,X,15841142,A,C,missense_variant(MODERATE|MISSENSE|aAa/aCa|p.Lys409Thr/c.1226A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1786,45,1838,"0,0244831338",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,12,Damaging,"20,98","14,6"
"low bq, bad alignment, many samples",UPN2_062,X,15841142,A,C,missense_variant(MODERATE|MISSENSE|aAa/aCa|p.Lys409Thr/c.1226A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),800,23,835,"0,0275449102",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,12,Damaging,"21,3","16,22"
"low bq, bad alignment, many samples",UPN2_063,X,15841142,A,C,missense_variant(MODERATE|MISSENSE|aAa/aCa|p.Lys409Thr/c.1226A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),912,33,955,"0,0345549738",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,12,Damaging,"21,09","15,15"
"low bq, bad alignment, many samples",UPN2_064,X,15841142,A,C,missense_variant(MODERATE|MISSENSE|aAa/aCa|p.Lys409Thr/c.1226A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3535,102,3666,"0,0278232406",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,12,Damaging,"21,39","14,44"
"low bq, bad alignment, many samples",UPN2_065,X,15841142,A,C,missense_variant(MODERATE|MISSENSE|aAa/aCa|p.Lys409Thr/c.1226A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3264,104,3387,"0,0307056392",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,12,Damaging,"21,99","14,52"
"low bq, bad alignment, many samples",UPN2_066,X,15841142,A,C,missense_variant(MODERATE|MISSENSE|aAa/aCa|p.Lys409Thr/c.1226A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1561,50,1625,"0,0307692308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,12,Damaging,"21,44","14,54"
"low bq, bad alignment, many samples",UPN2_067,X,15841142,A,C,missense_variant(MODERATE|MISSENSE|aAa/aCa|p.Lys409Thr/c.1226A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2112,66,2196,"0,0300546448",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,12,Damaging,"22,1","14,21"
"low bq, bad alignment, many samples",UPN2_068,X,15841142,A,C,missense_variant(MODERATE|MISSENSE|aAa/aCa|p.Lys409Thr/c.1226A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2197,66,2276,"0,0289982425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,12,Damaging,"21,19","14,65"
"low bq, bad alignment, many samples",UPN2_069,X,15841142,A,C,missense_variant(MODERATE|MISSENSE|aAa/aCa|p.Lys409Thr/c.1226A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1260,35,1308,"0,0267584098",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,12,Damaging,"21,71","14,91"
"low bq, bad alignment, many samples",UPN2_070,X,15841142,A,C,missense_variant(MODERATE|MISSENSE|aAa/aCa|p.Lys409Thr/c.1226A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1468,55,1532,"0,0359007833",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,12,Damaging,"20,65","14,13"
"low bq, bad alignment, many samples",UPN2_072,X,15841142,A,C,missense_variant(MODERATE|MISSENSE|aAa/aCa|p.Lys409Thr/c.1226A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1072,32,1115,"0,0286995516",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,12,Damaging,"21,65","14,22"
"low bq, bad alignment, many samples",UPN2_073,X,15841142,A,C,missense_variant(MODERATE|MISSENSE|aAa/aCa|p.Lys409Thr/c.1226A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1197,42,1244,"0,0337620579",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,12,Damaging,"21,24","14,86"
"low bq, bad alignment, many samples",UPN2_074,X,15841142,A,C,missense_variant(MODERATE|MISSENSE|aAa/aCa|p.Lys409Thr/c.1226A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1593,57,1657,"0,0343995172",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,12,Damaging,"21,29","14,89"
"low bq, bad alignment, many samples",UPN2_075,X,15841142,A,C,missense_variant(MODERATE|MISSENSE|aAa/aCa|p.Lys409Thr/c.1226A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1124,32,1159,"0,0276100086",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,12,Damaging,"21,83","16,06"
"low bq, bad alignment, many samples",UPN2_076,X,15841142,A,C,missense_variant(MODERATE|MISSENSE|aAa/aCa|p.Lys409Thr/c.1226A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1110,39,1156,"0,0337370242",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,12,Damaging,"21,2","14,67"
"low bq, bad alignment, many samples",UPN2_077,X,15841142,A,C,missense_variant(MODERATE|MISSENSE|aAa/aCa|p.Lys409Thr/c.1226A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1143,29,1187,"0,0244313395",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,12,Damaging,"21,07","15,1"
"low bq, bad alignment, many samples",UPN2_078,X,15841142,A,C,missense_variant(MODERATE|MISSENSE|aAa/aCa|p.Lys409Thr/c.1226A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),986,36,1027,"0,035053554",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,12,Damaging,"20,55","14,19"
"low bq, bad alignment, many samples",UPN2_079,X,15841142,A,C,missense_variant(MODERATE|MISSENSE|aAa/aCa|p.Lys409Thr/c.1226A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1062,39,1110,"0,0351351351",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,12,Damaging,"21,96","14,46"
"low bq, bad alignment, many samples",UPN2_081,X,15841142,A,C,missense_variant(MODERATE|MISSENSE|aAa/aCa|p.Lys409Thr/c.1226A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2216,59,2291,"0,0257529463",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,12,Damaging,"21,5","14,49"
"low bq, bad alignment, many samples",UPN2_082,X,15841142,A,C,missense_variant(MODERATE|MISSENSE|aAa/aCa|p.Lys409Thr/c.1226A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2977,76,3075,"0,0247154472",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,12,Damaging,"21,51","14,28"
"low bq, bad alignment, many samples",UPN2_083,X,15841142,A,C,missense_variant(MODERATE|MISSENSE|aAa/aCa|p.Lys409Thr/c.1226A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1146,33,1191,"0,0277078086",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,12,Damaging,"20,46","14,21"
"low bq, bad alignment, many samples",UPN2_084,X,15841142,A,C,missense_variant(MODERATE|MISSENSE|aAa/aCa|p.Lys409Thr/c.1226A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1602,48,1667,"0,0287942412",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,12,Damaging,"21,35","14,71"
"low bq, bad alignment, many samples",UPN2_085,X,15841142,A,C,missense_variant(MODERATE|MISSENSE|aAa/aCa|p.Lys409Thr/c.1226A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1382,45,1441,"0,0312283137",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,12,Damaging,"21,75",14
"low bq, bad alignment, many samples",UPN2_086,X,15841142,A,C,missense_variant(MODERATE|MISSENSE|aAa/aCa|p.Lys409Thr/c.1226A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2353,95,2472,"0,0384304207",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,12,Damaging,"21,32","14,64"
"low bq, bad alignment, many samples",UPN2_087,X,15841142,A,C,missense_variant(MODERATE|MISSENSE|aAa/aCa|p.Lys409Thr/c.1226A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1480,44,1529,"0,0287769784",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,12,Damaging,"21,87",15
"low bq, bad alignment, many samples",UPN2_088,X,15841142,A,C,missense_variant(MODERATE|MISSENSE|aAa/aCa|p.Lys409Thr/c.1226A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2414,93,2519,"0,0369194125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,12,Damaging,"21,52","15,1"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_095,X,15841142,A,C,missense_variant(MODERATE|MISSENSE|aAa/aCa|p.Lys409Thr/c.1226A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1982,24,2013,"0,0119225037",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,12,Damaging,"22,68","14,75"
"low bq, bad alignment, low freq, many artifacts",UPN2_103,X,15841142,A,C,missense_variant(MODERATE|MISSENSE|aAa/aCa|p.Lys409Thr/c.1226A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2301,26,2343,"0,0110968843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,17",Neutral,12,Damaging,"22,05","14,5"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_041,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3165,36,3242,"0,0111042566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"22,47","14,5"
"low bq, bad alignment, many samples",UPN2_089,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2077,48,2130,"0,0225352113",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"20,04","14,6"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_042,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4622,58,4734,"0,0122517955",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"21,78","14,72"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_043,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2625,29,2688,"0,0107886905",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"22,38",15
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_046,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2140,27,2191,"0,0123231401",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"21,53",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_047,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2728,53,2822,"0,0187810064",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"22,18","15,08"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_048,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3353,49,3442,"0,0142359094",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"21,96","14,27"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_006,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2548,33,2596,"0,0127118644",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"22,26","15,73"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_049,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1706,32,1758,"0,0182025028",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"21,69","14,69"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_050,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1463,20,1503,"0,0133067199",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"21,34","15,1"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_051,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2032,26,2083,"0,0124819971",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"22,12","15,69"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_052,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2487,28,2557,"0,0109503324",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"21,31","14,46"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_053,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4050,58,4165,"0,0139255702",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"21,35","14,97"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_007,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2124,22,2161,"0,010180472",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"23,36",15
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_010,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3457,38,3525,"0,0107801418",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"22,14","15,97"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_055,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4289,61,4403,"0,0138541903",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"21,56","16,03"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_056,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1397,27,1444,"0,0186980609",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"21,35","17,26"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_057,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1776,33,1833,"0,0180032733",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"21,82",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_058,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2262,36,2314,"0,0155574762",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"22,21","15,83"
"low bq, bad alignment, many samples",UPN2_059,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2470,144,2646,"0,0544217687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"18,65","14,66"
"low bq, bad alignment, many samples",UPN2_060,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),762,54,828,"0,0652173913",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"18,13","14,67"
"low bq, bad alignment, many samples",UPN2_091,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1035,28,1072,"0,026119403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"20,3","14,5"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_092,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1073,21,1098,"0,0191256831",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"20,05","15,05"
"low bq, bad alignment, many samples",UPN2_061,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1709,106,1838,"0,0576713819",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"18,3","14,19"
"low bq, bad alignment, many samples",UPN2_062,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),773,45,835,"0,0538922156",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"18,62","14,16"
"low bq, bad alignment, many samples",UPN2_063,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),887,51,955,"0,0534031414",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"18,19","14,25"
"low bq, bad alignment, many samples",UPN2_064,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3433,179,3664,"0,0488537118",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"18,24","14,6"
"low bq, bad alignment, many samples",UPN2_065,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3151,177,3386,"0,0522740697",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"18,88","14,68"
"low bq, bad alignment, many samples",UPN2_066,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1507,88,1623,"0,0542205792",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"18,52","14,28"
"low bq, bad alignment, many samples",UPN2_067,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2057,106,2195,"0,0482915718",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"18,66","14,65"
"low bq, bad alignment, many samples",UPN2_068,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2113,133,2275,"0,0584615385",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"18,33","15,25"
"low bq, bad alignment, many samples",UPN2_069,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1241,55,1308,"0,0420489297",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"18,52","15,02"
"low bq, bad alignment, many samples",UPN2_070,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1421,87,1530,"0,0568627451",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"18,27","14,67"
"low bq, bad alignment, many samples",UPN2_071,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),675,22,703,"0,0312944523",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,19,15
"low bq, bad alignment, many samples",UPN2_072,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1048,49,1115,"0,0439461883",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"18,48","14,53"
"low bq, bad alignment, many samples",UPN2_073,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1163,58,1244,"0,0466237942",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"18,61","14,74"
"low bq, bad alignment, many samples",UPN2_074,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1547,90,1655,"0,0543806647",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"18,37","14,6"
"low bq, bad alignment, many samples",UPN2_075,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1097,47,1159,"0,0405522002",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"18,4","14,28"
"low bq, bad alignment, many samples",UPN2_076,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1072,63,1156,"0,0544982699",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"18,47","14,32"
"low bq, bad alignment, many samples",UPN2_077,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1114,53,1187,"0,0446503791",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"18,78","14,38"
"low bq, bad alignment, many samples",UPN2_078,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),941,73,1027,"0,0710808179",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"18,48","15,03"
"low bq, bad alignment, many samples",UPN2_079,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1033,61,1110,"0,054954955",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"18,65","15,21"
"low bq, bad alignment, many samples",UPN2_080,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),746,41,796,"0,0515075377",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"18,05","15,12"
"low bq, bad alignment, many samples",UPN2_081,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2145,110,2291,"0,0480139677",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"18,75","14,68"
"low bq, bad alignment, many samples",UPN2_082,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2877,161,3075,"0,0523577236",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"18,68","15,01"
"low bq, bad alignment, many samples",UPN2_083,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1093,77,1191,"0,0646515533",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,18,"14,38"
"low bq, bad alignment, many samples",UPN2_084,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1546,101,1667,"0,0605878824",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"18,3","14,95"
"low bq, bad alignment, many samples",UPN2_085,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1337,87,1441,"0,0603747398",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"18,26","14,67"
"low bq, bad alignment, many samples",UPN2_086,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2311,117,2471,"0,0473492513",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"18,47","15,29"
"low bq, bad alignment, many samples",UPN2_087,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1432,79,1529,"0,0516677567",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"18,54","15,32"
"low bq, bad alignment, many samples",UPN2_088,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2351,142,2518,"0,0563939635",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"18,79","15,31"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_095,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1962,40,2013,"0,0198708395",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"19,77","14,73"
"low bq, bad alignment, many samples",UPN2_096,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1512,35,1554,"0,0225225225",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"20,03","16,26"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_097,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1710,35,1759,"0,0198976691",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"19,56","15,57"
"low bq, bad alignment, many samples",UPN2_098,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),939,23,964,"0,0238589212",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"19,78","14,87"
"low bq, bad alignment, many samples",UPN2_100,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1917,46,1973,"0,0233147491",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"20,27","14,57"
"low bq, bad alignment, many samples",UPN2_101,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),965,23,993,"0,0231621349",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"19,05","14,57"
"low bq, bad alignment, many samples",UPN2_103,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2250,69,2343,"0,0294494238",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"18,72","14,42"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_105,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1777,40,1825,"0,0219178082",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"19,14","14,5"
"low bq, bad alignment, many samples",UPN2_106,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1428,35,1467,"0,023858214",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"20,33",14
"low bq, bad alignment, many samples",UPN2_107,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1492,40,1544,"0,0259067358",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"19,6","15,45"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_108,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3366,60,3447,"0,0174064404",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"19,97","15,4"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_109,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1514,27,1547,"0,0174531351",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"19,71","15,63"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_110,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1083,20,1107,"0,0180668473",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"19,78","15,1"
"low bq, bad alignment, low freq, many artifacts",UPN2_111,X,15841143,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys409Asn/c.1227A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2809,58,2880,"0,0201388889",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,61",Neutral,"0,01",Damaging,"19,95","14,69"
"low bq, low freq, many artifacts",UPN2_047,X,15841144,C,A,missense_variant(MODERATE|MISSENSE|Cgc/Agc|p.Arg410Ser/c.1228C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2779,33,2822,"0,0116938342",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,22",Neutral,107,Tolerated,"33,4","23,73"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_059,X,15841147,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr411Pro/c.1231A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2584,28,2645,"0,0105860113",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,-1,Neutral,279,Tolerated,"23,89","14,71"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,X,15841147,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr411Pro/c.1231A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1787,25,1835,"0,0136239782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,-1,Neutral,279,Tolerated,"23,35","14,88"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,X,15841147,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr411Pro/c.1231A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3573,50,3661,"0,0136574706",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,-1,Neutral,279,Tolerated,"23,81","14,14"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_065,X,15841147,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr411Pro/c.1231A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3316,36,3383,"0,0106414425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,-1,Neutral,279,Tolerated,"24,44","14,36"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_066,X,15841147,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr411Pro/c.1231A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1583,26,1623,"0,0160197166",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,-1,Neutral,279,Tolerated,"24,27","15,12"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_067,X,15841147,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr411Pro/c.1231A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2142,29,2194,"0,0132178669",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,-1,Neutral,279,Tolerated,"24,66","14,76"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_068,X,15841147,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr411Pro/c.1231A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2224,27,2275,"0,0118681319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,-1,Neutral,279,Tolerated,"23,57","15,33"
"low bq, bad alignment, many samples",UPN2_076,X,15841147,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr411Pro/c.1231A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1115,26,1156,"0,0224913495",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,-1,Neutral,279,Tolerated,"23,49","16,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_081,X,15841147,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr411Pro/c.1231A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2240,27,2291,"0,0117852466",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,-1,Neutral,279,Tolerated,"24,6","14,48"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_082,X,15841147,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr411Pro/c.1231A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3015,31,3075,"0,0100813008",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,-1,Neutral,279,Tolerated,"24,31","14,71"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,X,15841147,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr411Pro/c.1231A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1639,20,1666,"0,0120048019",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,-1,Neutral,279,Tolerated,"23,42",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_085,X,15841147,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr411Pro/c.1231A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1402,24,1439,"0,0166782488",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,-1,Neutral,279,Tolerated,"23,69",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,X,15841147,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr411Pro/c.1231A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2411,29,2469,"0,011745646",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,-1,Neutral,279,Tolerated,"23,46",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_087,X,15841147,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr411Pro/c.1231A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1497,21,1528,"0,0137434555",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,-1,Neutral,279,Tolerated,"24,12",14
"low bq, bad alignment, low freq, many artifacts",UPN2_088,X,15841147,A,C,missense_variant(MODERATE|MISSENSE|Aca/Cca|p.Thr411Pro/c.1231A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2474,26,2518,"0,0103256553",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,-1,Neutral,279,Tolerated,"23,96","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_041,X,15841150,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser412Thr/c.1234T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3181,36,3241,"0,0111076828",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,452,Tolerated,"31,51","17,92"
"low bq, low freq, many artifacts, many samples",UPN2_043,X,15841150,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser412Thr/c.1234T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2641,27,2686,"0,0100521221",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,452,Tolerated,"31,69","15,78"
"low bq, low freq, many artifacts, many samples",UPN2_047,X,15841150,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser412Thr/c.1234T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2772,33,2821,"0,0116979794",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,452,Tolerated,"31,39","20,7"
"low bq, low freq, many artifacts, many samples",UPN2_048,X,15841150,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser412Thr/c.1234T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3386,35,3440,"0,0101744186",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,452,Tolerated,"31,19","18,86"
"low bq, low freq, many artifacts, many samples",UPN2_006,X,15841150,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser412Thr/c.1234T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2553,32,2596,"0,0123266564",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,452,Tolerated,"31,98","15,94"
"low bq, low freq, many artifacts, many samples",UPN2_049,X,15841150,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser412Thr/c.1234T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1714,32,1755,"0,0182336182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,452,Tolerated,"31,19","21,75"
"low bq, low freq, many artifacts, many samples",UPN2_051,X,15841150,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser412Thr/c.1234T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2034,25,2080,"0,0120192308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,452,Tolerated,"31,43","15,6"
"low bq, low freq, many artifacts, many samples",UPN2_053,X,15841150,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser412Thr/c.1234T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4073,54,4161,"0,0129776496",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,452,Tolerated,"30,98","17,11"
"low bq, low freq, many artifacts, many samples",UPN2_011,X,15841150,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser412Thr/c.1234T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3143,51,3205,"0,0159126365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,452,Tolerated,"32,03","20,75"
"low bq, low freq, many artifacts, many samples",UPN2_055,X,15841150,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser412Thr/c.1234T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4313,49,4395,"0,011149033",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,452,Tolerated,"31,14","18,04"
"low bq, low freq, many artifacts, many samples",UPN2_057,X,15841150,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser412Thr/c.1234T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1793,25,1832,"0,0136462882",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,452,Tolerated,"30,95","21,4"
"low bq, low freq, many artifacts, many samples",UPN2_058,X,15841150,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser412Thr/c.1234T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2268,24,2313,"0,0103761349",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,452,Tolerated,"31,37","17,5"
"low bq, low freq, many artifacts, many samples",UPN2_065,X,15841150,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser412Thr/c.1234T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3315,35,3380,"0,0103550296",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,452,Tolerated,"30,05","16,51"
"low bq, low freq, many artifacts",UPN2_081,X,15841150,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser412Thr/c.1234T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2251,23,2290,"0,0100436681",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,54",Neutral,452,Tolerated,"29,95",17
"low bq, low freq, many artifacts, many samples",UPN2_059,X,15841156,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser414Arg/c.1240A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2595,37,2640,"0,0140151515",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"28,24","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_061,X,15841156,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser414Arg/c.1240A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1804,24,1831,"0,0131075915",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"28,02","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_064,X,15841156,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser414Arg/c.1240A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3592,45,3657,"0,0123051682",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"28,43","14,8"
"low bq, low freq, many artifacts, many samples",UPN2_065,X,15841156,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser414Arg/c.1240A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3317,39,3377,"0,0115487119",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"28,48","14,33"
"low bq, low freq, many artifacts, many samples",UPN2_066,X,15841156,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser414Arg/c.1240A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1589,29,1622,"0,0178791615",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"28,4",15
"low bq, low freq, many artifacts, many samples",UPN2_067,X,15841156,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser414Arg/c.1240A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2158,25,2191,"0,0114103149",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"28,67","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_068,X,15841156,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser414Arg/c.1240A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2225,36,2269,"0,0158660203",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"28,26","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_069,X,15841156,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser414Arg/c.1240A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1277,24,1306,"0,0183767228",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"28,56",14
"low bq, low freq, many artifacts, many samples",UPN2_072,X,15841156,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser414Arg/c.1240A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1089,20,1113,"0,0179694519",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"28,54",14
"low bq, low freq, many artifacts, many samples",UPN2_074,X,15841156,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser414Arg/c.1240A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1628,24,1655,"0,0145015106",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"28,53","15,96"
"low bq, low freq, many artifacts, many samples",UPN2_081,X,15841156,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser414Arg/c.1240A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2255,31,2289,"0,0135430319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"28,53","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_082,X,15841156,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser414Arg/c.1240A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3014,33,3072,"0,0107421875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"28,75",14
"low bq, low freq, many artifacts, many samples",UPN2_083,X,15841156,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser414Arg/c.1240A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1161,23,1188,"0,0193602694",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"28,05","14,78"
"low bq, low freq, many artifacts, many samples",UPN2_085,X,15841156,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser414Arg/c.1240A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1411,21,1436,"0,0146239554",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"28,53","14,86"
"low bq, low freq, many artifacts, many samples",UPN2_086,X,15841156,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser414Arg/c.1240A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2424,28,2463,"0,0113682501",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"27,87",14
"low bq, low freq, many artifacts, many samples",UPN2_087,X,15841156,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser414Arg/c.1240A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1500,20,1526,"0,0131061599",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"28,59","15,35"
"low bq, low freq, many artifacts",UPN2_088,X,15841156,A,C,missense_variant(MODERATE|MISSENSE|Agt/Cgt|p.Ser414Arg/c.1240A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2471,35,2518,"0,0138999206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"28,2","14,63"
"low bq, low freq, many artifacts, many samples",UPN2_002,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1445,23,1481,"0,0155300473",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"30,22","15,52"
"low bq, low freq, many artifacts, many samples",UPN2_022,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3516,40,3576,"0,0111856823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"31,68","15,77"
"low bq, low freq, many artifacts, many samples",UPN2_023,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1632,25,1663,"0,0150330728",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"31,7","16,12"
"low bq, low freq, many artifacts, many samples",UPN2_041,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3151,54,3238,"0,0166769611",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"30,7","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_025,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4412,52,4491,"0,011578713",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"31,67","15,52"
"low bq, low freq, many artifacts, many samples",UPN2_026,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3474,48,3539,"0,0135631534",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"31,63","18,1"
"low bq, low freq, many artifacts, many samples",UPN2_027,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2078,25,2118,"0,0118035883",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"31,49","15,96"
"low bq, low freq, many artifacts, many samples",UPN2_042,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4609,75,4724,"0,015876376",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"30,63","16,59"
"low bq, low freq, many artifacts, many samples",UPN2_028,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1663,22,1700,"0,0129411765",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"31,51","15,41"
"low bq, low freq, many artifacts, many samples",UPN2_043,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2628,44,2683,"0,0163995527",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"30,99","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_030,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1998,23,2030,"0,0113300493",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"31,42","16,7"
"low bq, low freq, many artifacts, many samples",UPN2_045,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1097,23,1127,"0,0204081633",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"30,49","15,35"
"low bq, low freq, many artifacts, many samples",UPN2_046,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2133,41,2186,"0,0187557182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"30,45","16,22"
"low bq, low freq, many artifacts, many samples",UPN2_047,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2756,58,2832,"0,020480226",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"30,87","15,83"
"low bq, low freq, many artifacts, many samples",UPN2_048,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3350,56,3438,"0,0162885398",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"30,54","17,38"
"low bq, low freq, many artifacts, many samples",UPN2_035,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4656,57,4732,"0,0120456467",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"31,49","16,49"
"low bq, low freq, many artifacts, many samples",UPN2_036,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2393,26,2429,"0,0107039934",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"31,5","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_006,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2536,32,2591,"0,0123504438",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"30,74","17,47"
"low bq, low freq, many artifacts, many samples",UPN2_049,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1709,23,1746,"0,0131729668",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"30,21","16,7"
"low bq, low freq, many artifacts, many samples",UPN2_050,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1461,23,1501,"0,0153231179",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"30,23","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_051,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2023,33,2075,"0,0159036145",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"30,65","16,64"
"low bq, low freq, many artifacts, many samples",UPN2_052,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2482,39,2553,"0,0152761457",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"30,59","17,95"
"low bq, low freq, many artifacts, many samples",UPN2_038,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2853,37,2911,"0,0127104088",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"31,53","16,86"
"low bq, low freq, many artifacts, many samples",UPN2_039,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3380,37,3434,"0,0107746069",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"31,46","17,11"
"low bq, low freq, many artifacts, many samples",UPN2_053,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4057,71,4153,"0,0170960751",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"30,32","16,48"
"low bq, low freq, many artifacts, many samples",UPN2_054,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1436,22,1468,"0,014986376",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"30,45","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_007,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2111,33,2158,"0,015291937",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"31,65","15,06"
"low bq, low freq, many artifacts, many samples",UPN2_008,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2980,35,3031,"0,0115473441",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"30,97","15,26"
"low bq, low freq, many artifacts, many samples",UPN2_009,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4502,56,4581,"0,0122244052",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"31,03","16,52"
"low bq, low freq, many artifacts, many samples",UPN2_010,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3452,47,3522,"0,0133446905",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"30,97","15,85"
"low bq, low freq, many artifacts, many samples",UPN2_011,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3137,40,3205,"0,0124804992",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"30,81","16,55"
"low bq, low freq, many artifacts, many samples",UPN2_055,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4273,77,4384,"0,0175638686",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"30,53","16,7"
"low bq, low freq, many artifacts, many samples",UPN2_057,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1781,36,1828,"0,0196936543",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"30,12","17,72"
"low bq, low freq, many artifacts, many samples",UPN2_058,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2264,28,2307,"0,0121369744",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"31,01","15,5"
"low bq, low freq, many artifacts, many samples",UPN2_059,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2558,33,2636,"0,0125189681",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"28,32","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_040,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3592,41,3647,"0,0112421168",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"31,71","19,54"
"low bq, low freq, many artifacts, many samples",UPN2_061,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1773,29,1832,"0,0158296943",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"28,51","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_064,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3549,52,3649,"0,0142504796",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"28,16","16,21"
"low bq, low freq, many artifacts, many samples",UPN2_065,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3289,40,3375,"0,0118518519",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"28,57","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_066,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1576,23,1620,"0,0141975309",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"28,23",14
"low bq, low freq, many artifacts, many samples",UPN2_067,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2129,33,2189,"0,0150753769",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"28,94","15,88"
"low bq, low freq, many artifacts, many samples",UPN2_068,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2188,32,2265,"0,0141280353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"28,01","15,5"
"low bq, low freq, many artifacts, many samples",UPN2_069,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1262,20,1306,"0,0153139357",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"28,43","15,1"
"low bq, low freq, many artifacts, many samples",UPN2_070,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1485,20,1524,"0,0131233596",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"28,1","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_081,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2207,42,2286,"0,0183727034",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"28,26","16,38"
"low bq, low freq, many artifacts, many samples",UPN2_082,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2974,54,3067,"0,0176067819",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"28,3","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_084,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1615,23,1662,"0,0138387485",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"27,99",14
"low bq, low freq, many artifacts, many samples",UPN2_085,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1386,25,1434,"0,0174337517",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"28,25",14
"low bq, low freq, many artifacts, many samples",UPN2_086,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2377,34,2458,"0,0138323841",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"27,66","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_087,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1481,21,1524,"0,0137795276",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"28,27",14
"low bq, low freq, many artifacts",UPN2_088,X,15841158,T,A,missense_variant(MODERATE|MISSENSE|agT/agA|p.Ser414Arg/c.1242T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2450,31,2514,"0,0123309467",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"28,55","15,71"
"low bq, low freq, many artifacts",UPN2_074,X,15841158,T,G,missense_variant(MODERATE|MISSENSE|agT/agG|p.Ser414Arg/c.1242T>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),1609,23,1652,"0,0139225182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,66",Neutral,386,Tolerated,"27,86","14,96"
"low freq, many artifacts",UPN2_006,X,15841162,G,A,missense_variant(MODERATE|MISSENSE|Gag/Aag|p.Glu416Lys/c.1246G>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2562,34,2605,"0,0130518234",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,"0,046",Damaging,"33,7","33,76"
"low bq, low freq, many artifacts, many samples",UPN2_041,X,15841163,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu416Val/c.1247A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),3183,38,3240,"0,0117283951",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,83",Deleterious,"0,01",Damaging,"29,7","18,29"
"low bq, low freq, many artifacts, many samples",UPN2_046,X,15841163,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu416Val/c.1247A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),2157,22,2196,"0,0100182149",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,83",Deleterious,"0,01",Damaging,"28,46","16,91"
"low bq, low freq, many artifacts, many samples",UPN2_048,X,15841163,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu416Val/c.1247A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),3380,37,3447,"0,0107339716",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,83",Deleterious,"0,01",Damaging,"28,94","16,49"
"low bq, low freq, many artifacts, many samples",UPN2_050,X,15841163,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu416Val/c.1247A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),1482,20,1507,"0,0132714001",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,83",Deleterious,"0,01",Damaging,"29,12","15,55"
"low bq, low freq, many artifacts, many samples",UPN2_051,X,15841163,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu416Val/c.1247A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),2051,21,2081,"0,0100913023",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,83",Deleterious,"0,01",Damaging,"29,37","18,19"
"low bq, low freq, many artifacts, many samples",UPN2_052,X,15841163,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu416Val/c.1247A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),2508,35,2555,"0,0136986301",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,83",Deleterious,"0,01",Damaging,"28,29","16,51"
"low bq, low freq, many artifacts, many samples",UPN2_053,X,15841163,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu416Val/c.1247A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),4094,44,4166,"0,0105616899",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,83",Deleterious,"0,01",Damaging,"28,71","16,09"
"low bq, low freq, many artifacts, many samples",UPN2_054,X,15841163,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu416Val/c.1247A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),1458,20,1483,"0,0134861767",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,83",Deleterious,"0,01",Damaging,"28,13","18,6"
"low bq, low freq, many artifacts, many samples",UPN2_055,X,15841163,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu416Val/c.1247A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),4339,50,4412,"0,0113327289",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,83",Deleterious,"0,01",Damaging,"28,7","17,54"
"low bq, low freq, many artifacts, many samples",UPN2_057,X,15841163,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu416Val/c.1247A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),1805,22,1834,"0,0119956379",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,83",Deleterious,"0,01",Damaging,"29,56",16
"low bq, bad alignment, low freq, many artifacts",UPN2_061,X,15841163,A,T,missense_variant(MODERATE|MISSENSE|gAg/gTg|p.Glu416Val/c.1247A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),1787,33,1835,"0,0179836512",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,83",Deleterious,"0,01",Damaging,"25,4","16,76"
"low bq, bad alignment, many samples",UPN2_059,X,15841169,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His418Pro/c.1253A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),5114,140,5304,"0,0263951735",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,33",Deleterious,21,Damaging,"26,04","14,4"
"low bq, bad alignment, many samples",UPN2_060,X,15841169,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His418Pro/c.1253A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1580,56,1659,"0,0337552743",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,33",Deleterious,21,Damaging,"26,01","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_092,X,15841169,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His418Pro/c.1253A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2147,31,2199,"0,014097317",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,33",Deleterious,21,Damaging,"27,4","16,58"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,X,15841169,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His418Pro/c.1253A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3566,70,3685,"0,0189959294",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,33",Deleterious,21,Damaging,"26,35","14,37"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,X,15841169,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His418Pro/c.1253A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1605,36,1661,"0,0216736905",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,33",Deleterious,21,Damaging,"26,37","15,36"
"low bq, bad alignment, many samples",UPN2_063,X,15841169,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His418Pro/c.1253A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),907,31,960,"0,0322916667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,33",Deleterious,21,Damaging,"19,23","14,42"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,X,15841169,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His418Pro/c.1253A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),7063,139,7323,"0,0189812918",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,33",Deleterious,21,Damaging,26,"15,76"
"low bq, bad alignment, many samples",UPN2_065,X,15841169,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His418Pro/c.1253A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),6533,162,6769,"0,0239326341",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,33",Deleterious,21,Damaging,"26,22","14,69"
"low bq, bad alignment, many samples",UPN2_066,X,15841169,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His418Pro/c.1253A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3161,84,3273,"0,025664528",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,33",Deleterious,21,Damaging,"25,89","15,23"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_067,X,15841169,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His418Pro/c.1253A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4237,90,4386,"0,0205198358",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,33",Deleterious,21,Damaging,"26,27","14,59"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_068,X,15841169,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His418Pro/c.1253A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4429,70,4562,"0,0153441473",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,33",Deleterious,21,Damaging,"25,87","14,26"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_069,X,15841169,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His418Pro/c.1253A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2557,42,2616,"0,0160550459",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,33",Deleterious,21,Damaging,"26,72","14,31"
"low bq, bad alignment, many samples",UPN2_070,X,15841169,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His418Pro/c.1253A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1464,50,1543,"0,032404407",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,33",Deleterious,21,Damaging,"19,83","14,14"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,X,15841169,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His418Pro/c.1253A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2167,41,2238,"0,0183199285",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,33",Deleterious,21,Damaging,"26,14","14,32"
"low bq, bad alignment, many samples",UPN2_073,X,15841169,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His418Pro/c.1253A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2401,64,2490,"0,0257028112",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,33",Deleterious,21,Damaging,"26,27","14,11"
"low bq, bad alignment, many samples",UPN2_074,X,15841169,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His418Pro/c.1253A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3207,79,3321,"0,0237880157",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,33",Deleterious,21,Damaging,"25,99","14,51"
"low bq, bad alignment, many samples",UPN2_075,X,15841169,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His418Pro/c.1253A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1091,54,1156,"0,0467128028",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,33",Deleterious,21,Damaging,"19,37",14
"low bq, bad alignment, many samples",UPN2_076,X,15841169,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His418Pro/c.1253A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2213,54,2306,"0,0234171726",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,33",Deleterious,21,Damaging,"26,01","14,24"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,X,15841169,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His418Pro/c.1253A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2304,37,2369,"0,0156184044",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,33",Deleterious,21,Damaging,"26,34","15,08"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,X,15841169,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His418Pro/c.1253A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2000,37,2058,"0,01797862",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,33",Deleterious,21,Damaging,"25,89","14,84"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_079,X,15841169,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His418Pro/c.1253A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2159,34,2212,"0,0153707052",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,33",Deleterious,21,Damaging,"25,93","14,41"
"low bq, bad alignment, many samples",UPN2_080,X,15841169,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His418Pro/c.1253A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),750,25,795,"0,0314465409",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,33",Deleterious,21,Damaging,"19,32",14
"low bq, bad alignment, many samples",UPN2_081,X,15841169,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His418Pro/c.1253A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4417,120,4594,"0,0261210274",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,33",Deleterious,21,Damaging,"26,2","14,57"
"low bq, bad alignment, many samples",UPN2_082,X,15841169,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His418Pro/c.1253A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),5946,137,6155,"0,0222583266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,33",Deleterious,21,Damaging,"26,29","14,66"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,X,15841169,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His418Pro/c.1253A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2305,35,2384,"0,0146812081",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,33",Deleterious,21,Damaging,"25,65","14,89"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,X,15841169,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His418Pro/c.1253A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3258,36,3341,"0,010775217",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,33",Deleterious,21,Damaging,"25,8","14,36"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_085,X,15841169,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His418Pro/c.1253A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2805,48,2884,"0,0166435506",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,33",Deleterious,21,Damaging,"26,16","15,19"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,X,15841169,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His418Pro/c.1253A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4812,95,4962,"0,0191455058",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,33",Deleterious,21,Damaging,"26,13","14,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_087,X,15841169,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His418Pro/c.1253A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2963,52,3068,"0,0169491525",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,33",Deleterious,21,Damaging,"26,05","14,67"
"low bq, bad alignment, many samples",UPN2_088,X,15841169,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His418Pro/c.1253A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4854,146,5047,"0,0289280761",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,33",Deleterious,21,Damaging,"26,37","14,72"
"low bq, low freq, many artifacts, many samples",UPN2_100,X,15841169,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His418Pro/c.1253A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3876,47,3941,"0,0119259071",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,33",Deleterious,21,Damaging,"27,57",14
"low bq, low freq, many artifacts",UPN2_107,X,15841169,A,C,missense_variant(MODERATE|MISSENSE|cAc/cCc|p.His418Pro/c.1253A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3039,40,3092,"0,0129366106",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,33",Deleterious,21,Damaging,"27,21",14
"low bq, low freq, many artifacts",UPN2_047,X,15841169,A,G,missense_variant(MODERATE|MISSENSE|cAc/cGc|p.His418Arg/c.1253A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),5560,66,5667,"0,0116463737",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,95",Neutral,"0,288",Tolerated,"28,2","26,32"
"low bq, bad alignment, low freq, many artifacts",UPN2_070,X,15841170,C,G,missense_variant(MODERATE|MISSENSE|caC/caG|p.His418Gln/c.1254C>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),1513,22,1540,"0,0142857143",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,6",Neutral,32,Damaging,"25,81",14
"low bq, low freq, many artifacts, many samples",UPN2_059,X,15841171,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn419His/c.1255A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),5174,86,5303,"0,0162172355",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,52,Tolerated,"27,08","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_060,X,15841171,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn419His/c.1255A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1621,20,1660,"0,0120481928",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,52,Tolerated,"27,11",14
"low bq, low freq, many artifacts, many samples",UPN2_061,X,15841171,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn419His/c.1255A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3587,56,3683,"0,0152049959",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,52,Tolerated,"27,03","14,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,X,15841171,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn419His/c.1255A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1621,26,1659,"0,0156720916",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,52,Tolerated,"26,66","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_064,X,15841171,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn419His/c.1255A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),7140,114,7326,"0,0155610156",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,52,Tolerated,"27,07","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_065,X,15841171,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn419His/c.1255A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),6642,77,6769,"0,0113753878",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,52,Tolerated,"27,37","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_066,X,15841171,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn419His/c.1255A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3190,51,3269,"0,0156011013",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,52,Tolerated,"27,17","15,33"
"low bq, low freq, many artifacts, many samples",UPN2_067,X,15841171,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn419His/c.1255A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4287,59,4387,"0,0134488261",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,52,Tolerated,"27,52",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_068,X,15841171,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn419His/c.1255A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4455,60,4559,"0,0131607809",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,52,Tolerated,"26,99","14,7"
"low bq, low freq, many artifacts, many samples",UPN2_069,X,15841171,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn419His/c.1255A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2556,35,2614,"0,0133894415",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,52,Tolerated,"27,07",14
"low bq, bad alignment, many samples",UPN2_070,X,15841171,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn419His/c.1255A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1485,43,1540,"0,0279220779",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,52,Tolerated,"21,02",14
"low bq, low freq, many artifacts, many samples",UPN2_071,X,15841171,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn419His/c.1255A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1369,21,1407,"0,0149253731",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,52,Tolerated,"27,44",14
"low bq, low freq, many artifacts, many samples",UPN2_072,X,15841171,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn419His/c.1255A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2176,34,2237,"0,0151989271",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,52,Tolerated,"27,71","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_073,X,15841171,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn419His/c.1255A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2437,30,2487,"0,0120627262",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,52,Tolerated,"27,11","14,67"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,X,15841171,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn419His/c.1255A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3257,40,3320,"0,0120481928",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,52,Tolerated,"26,81","15,12"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_075,X,15841171,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn419His/c.1255A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1119,21,1154,"0,0181975737",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,52,Tolerated,"22,16",14
"low bq, low freq, many artifacts, many samples",UPN2_076,X,15841171,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn419His/c.1255A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2245,34,2304,"0,0147569444",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,52,Tolerated,"27,08","14,59"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,X,15841171,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn419His/c.1255A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2324,33,2367,"0,0139416984",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,52,Tolerated,"26,9","14,21"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,X,15841171,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn419His/c.1255A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2006,22,2053,"0,0107160253",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,52,Tolerated,"26,48","15,41"
"low bq, low freq, many artifacts, many samples",UPN2_079,X,15841171,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn419His/c.1255A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2159,35,2212,"0,0158227848",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,52,Tolerated,"27,38","14,37"
"low bq, bad alignment, many samples",UPN2_080,X,15841171,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn419His/c.1255A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),767,20,793,"0,025220681",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,52,Tolerated,"22,07",14
"low bq, low freq, many artifacts, many samples",UPN2_081,X,15841171,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn419His/c.1255A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4487,62,4593,"0,0134988025",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,52,Tolerated,"27,41",14
"low bq, low freq, many artifacts, many samples",UPN2_082,X,15841171,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn419His/c.1255A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),6019,87,6152,"0,0141417425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,52,Tolerated,"27,18","14,55"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,X,15841171,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn419His/c.1255A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2321,33,2385,"0,013836478",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,52,Tolerated,"26,85","14,61"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,X,15841171,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn419His/c.1255A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3263,41,3341,"0,0122717749",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,52,Tolerated,"26,91",14
"low bq, low freq, many artifacts, many samples",UPN2_085,X,15841171,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn419His/c.1255A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2813,49,2881,"0,0170079833",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,52,Tolerated,"27,03","14,73"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,X,15841171,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn419His/c.1255A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4834,84,4957,"0,0169457333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,52,Tolerated,"26,83","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_087,X,15841171,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn419His/c.1255A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2986,48,3066,"0,0156555773",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,52,Tolerated,"27,12",14
"low bq, low freq, many artifacts",UPN2_088,X,15841171,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn419His/c.1255A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4908,80,5042,"0,0158667196",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,09",Neutral,52,Tolerated,"27,51","14,65"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,X,15841172,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn419Thr/c.1256A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3603,37,3682,"0,0100488865",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,161,Tolerated,"25,79",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,X,15841172,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn419Thr/c.1256A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1626,21,1659,"0,0126582278",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,161,Tolerated,"25,46","14,62"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_065,X,15841172,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn419Thr/c.1256A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),6631,70,6765,"0,0103473762",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,161,Tolerated,"26,11","14,47"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_068,X,15841172,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn419Thr/c.1256A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4468,55,4559,"0,0120640491",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,161,Tolerated,"25,49","14,73"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_069,X,15841172,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn419Thr/c.1256A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2564,32,2615,"0,0122370937",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,161,Tolerated,"25,9","14,69"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,X,15841172,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn419Thr/c.1256A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2444,27,2486,"0,0108608206",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,161,Tolerated,"26,11",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,X,15841172,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn419Thr/c.1256A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2256,25,2307,"0,0108365843",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,161,Tolerated,"25,8","14,52"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,X,15841172,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn419Thr/c.1256A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2318,31,2365,"0,0131078224",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,161,Tolerated,"25,82","15,71"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,X,15841172,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn419Thr/c.1256A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2006,22,2053,"0,0107160253",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,161,Tolerated,"25,17",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_079,X,15841172,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn419Thr/c.1256A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2164,25,2213,"0,0112968821",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,161,Tolerated,"25,86",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_081,X,15841172,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn419Thr/c.1256A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4496,47,4594,"0,0102307357",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,161,Tolerated,"26,13","14,89"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,X,15841172,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn419Thr/c.1256A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2334,27,2386,"0,0113160101",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,161,Tolerated,"25,4","15,63"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_085,X,15841172,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn419Thr/c.1256A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2800,47,2881,"0,0163137799",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,161,Tolerated,"25,95","14,28"
"low bq, bad alignment, low freq, many artifacts",UPN2_086,X,15841172,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn419Thr/c.1256A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4856,58,4956,"0,0117029863",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,51",Neutral,161,Tolerated,"25,63","14,22"
"low bq, low freq, many artifacts",UPN2_056,X,15841172,A,T,missense_variant(MODERATE|MISSENSE|aAt/aTt|p.Asn419Ile/c.1256A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),2830,33,2881,"0,0114543561",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,23",Deleterious,55,Tolerated,"28,66","20,55"
"low bq, bad alignment, many samples",UPN2_001,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),655,23,689,"0,0333817126",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"26,31","16,87"
"low bq, low freq, many artifacts, many samples",UPN2_015,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),5027,53,5123,"0,0103455007",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"29,51","15,25"
"low bq, low freq, many artifacts, many samples",UPN2_016,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2343,34,2392,"0,0142140468",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"29,86","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_002,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2900,39,2975,"0,0131092437",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"28,91","15,36"
"low bq, low freq, many artifacts, many samples",UPN2_022,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),7063,73,7179,"0,0101685472",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"29,82","15,56"
"low bq, low freq, many artifacts, many samples",UPN2_023,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3273,35,3333,"0,0105010501",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"29,63","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_041,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),6293,116,6503,"0,017837921",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"29,32","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_024,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1429,24,1463,"0,016404648",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"30,05","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_025,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),8833,114,9006,"0,0126582278",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"29,69","16,06"
"low bq, low freq, many artifacts, many samples",UPN2_027,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4177,46,4260,"0,0107981221",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"29,55","16,48"
"low bq, low freq, many artifacts, many samples",UPN2_042,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),9240,149,9514,"0,015661131",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"29,26","14,96"
"low bq, low freq, many artifacts, many samples",UPN2_028,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3343,42,3407,"0,0123275609",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"29,39","15,69"
"low bq, low freq, many artifacts, many samples",UPN2_043,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),5251,94,5415,"0,0173591874",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"29,2","15,73"
"low bq, low freq, many artifacts, many samples",UPN2_044,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1842,28,1895,"0,0147757256",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"29,17","14,5"
"low bq, low freq, many artifacts, many samples",UPN2_029,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2720,35,2779,"0,0125944584",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"29,86","15,66"
"low bq, low freq, many artifacts, many samples",UPN2_045,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2203,24,2269,"0,0105773468",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"29,35","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_046,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4299,69,4433,"0,0155650801",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"29,1","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_033,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2603,34,2652,"0,0128205128",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"29,73","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_047,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),5443,106,5668,"0,018701482",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"29,09","15,78"
"low bq, low freq, many artifacts, many samples",UPN2_048,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),6723,108,6908,"0,0156340475",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"29,16","15,46"
"low bq, low freq, many artifacts, many samples",UPN2_035,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),9279,115,9475,"0,0121372032",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"29,78","15,65"
"low bq, low freq, many artifacts, many samples",UPN2_036,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4635,52,4731,"0,0109913338",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"29,65","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_006,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),5084,59,5195,"0,0113570741",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"29,06","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_049,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3428,62,3532,"0,0175537939",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"29,17","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_050,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2921,55,3021,"0,0182058921",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"28,87","15,95"
"low bq, low freq, many artifacts, many samples",UPN2_037,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),7887,85,8040,"0,0105721393",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"29,54",15
"low bq, low freq, many artifacts, many samples",UPN2_051,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4065,74,4181,"0,017699115",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,29,"14,58"
"low bq, low freq, many artifacts, many samples",UPN2_052,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4960,84,5125,"0,0163902439",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"29,07","14,88"
"low bq, low freq, many artifacts, many samples",UPN2_038,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),5724,67,5831,"0,0114903104",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"29,63","15,73"
"low bq, low freq, many artifacts, many samples",UPN2_039,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),6771,70,6881,"0,01017294",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"29,53","15,09"
"low bq, low freq, many artifacts, many samples",UPN2_053,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),8090,155,8349,"0,0185650976",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"29,06","15,79"
"low bq, low freq, many artifacts, many samples",UPN2_054,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2857,47,2955,"0,0159052453",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"28,72","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_007,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4283,56,4362,"0,0128381476",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"29,76","15,89"
"low bq, low freq, many artifacts, many samples",UPN2_008,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),5932,68,6048,"0,0112433862",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"29,37","15,16"
"low bq, low freq, many artifacts, many samples",UPN2_009,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),8957,117,9167,"0,0127631722",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"29,46","15,48"
"low bq, low freq, many artifacts, many samples",UPN2_010,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),5114,92,5261,"0,0174871697",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"28,42","15,91"
"low bq, low freq, many artifacts, many samples",UPN2_011,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),6289,87,6434,"0,0135219148",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"29,45","15,99"
"low bq, low freq, many artifacts, many samples",UPN2_055,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),8540,155,8821,"0,0175717039",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"29,04","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_056,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2813,35,2881,"0,0121485595",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"28,95","15,6"
"low bq, low freq, many artifacts, many samples",UPN2_057,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3553,62,3670,"0,016893733",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"29,02","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_058,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4508,84,4642,"0,0180956484",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,29,"17,27"
"low bq, low freq, many artifacts, many samples",UPN2_059,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),5072,68,5306,"0,0128156804",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"27,29","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_012,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2002,32,2049,"0,0156173743",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"29,28","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_060,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1578,23,1660,"0,0138554217",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"27,54",14
"low bq, low freq, many artifacts, many samples",UPN2_040,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),7169,91,7309,"0,0124504036",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"29,74","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_091,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2101,28,2165,"0,0129330254",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"28,87","14,89"
"low bq, low freq, many artifacts, many samples",UPN2_061,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3507,43,3683,"0,0116752647",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"27,12","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_062,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1573,22,1661,"0,0132450331",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"27,04",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),892,20,978,"0,0204498978",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"21,29","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_064,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),7010,75,7325,"0,0102389078",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"27,2","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_065,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),6470,90,6761,"0,0133116403",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"27,37","15,61"
"low bq, low freq, many artifacts, many samples",UPN2_066,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3112,54,3270,"0,0165137615",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"27,38","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_067,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4204,62,4386,"0,0141358869",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"27,47",14
"low bq, bad alignment, many samples",UPN2_070,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1400,39,1555,"0,0250803859",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"21,22",14
"low bq, low freq, many artifacts, many samples",UPN2_072,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2124,26,2237,"0,011622709",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"27,13",14
"low bq, low freq, many artifacts, many samples",UPN2_073,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2364,29,2484,"0,0116747182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"27,44",14
"low bq, low freq, many artifacts, many samples",UPN2_074,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3169,49,3317,"0,0147723847",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"27,3","14,27"
"low bq, bad alignment, many samples",UPN2_075,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1081,34,1180,"0,0288135593",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"21,45","16,09"
"low bq, low freq, many artifacts, many samples",UPN2_076,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2209,24,2308,"0,0103986135",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"27,18",14
"low bq, low freq, many artifacts, many samples",UPN2_077,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2241,24,2366,"0,0101437025",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"27,39","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_078,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1950,26,2051,"0,0126767431",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"27,16","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_079,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2098,40,2214,"0,0180668473",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"27,42","14,9"
"low bq, bad alignment, many samples",UPN2_080,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),743,20,803,"0,0249066002",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"21,55",14
"low bq, low freq, many artifacts, many samples",UPN2_081,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4386,59,4591,"0,0128512307",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"27,39","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_082,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),5862,89,6152,"0,0144668401",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"27,32","14,49"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2284,35,2387,"0,0146627566",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"26,9","15,74"
"low bq, low freq, many artifacts, many samples",UPN2_084,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3191,47,3341,"0,0140676444",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"27,1",14
"low bq, low freq, many artifacts, many samples",UPN2_085,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2746,43,2880,"0,0149305556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"27,22","15,95"
"low bq, low freq, many artifacts, many samples",UPN2_086,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4726,52,4955,"0,0104944501",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"27,1",14
"low bq, low freq, many artifacts, many samples",UPN2_087,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2924,40,3065,"0,013050571",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"27,23","16,35"
"low bq, low freq, many artifacts",UPN2_088,X,15841173,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn419Lys/c.1257T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4833,65,5042,"0,0128917096",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"27,18","15,82"
"low bq, low freq, many artifacts, many samples",UPN2_089,X,15841173,T,G,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn419Lys/c.1257T>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),4185,58,4286,"0,0135324312",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"28,82",14
"low bq, low freq, many artifacts, many samples",UPN2_093,X,15841173,T,G,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn419Lys/c.1257T>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),2993,42,3072,"0,013671875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"28,98","17,38"
"low bq, many samples",UPN2_068,X,15841173,T,G,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn419Lys/c.1257T>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),4368,137,4558,"0,0300570426",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"27,21","14,28"
"low bq, many samples",UPN2_069,X,15841173,T,G,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn419Lys/c.1257T>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),2489,89,2615,"0,0340344168",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"27,36",14
"low bq, many samples",UPN2_071,X,15841173,T,G,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn419Lys/c.1257T>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),1338,48,1406,"0,0341394026",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"27,3",14
"low bq, low freq, many artifacts, many samples",UPN2_094,X,15841173,T,G,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn419Lys/c.1257T>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),1951,30,2008,"0,014940239",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"28,56",14
"low bq, low freq, many artifacts, many samples",UPN2_095,X,15841173,T,G,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn419Lys/c.1257T>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),3927,55,4026,"0,0136612022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"28,39",14
"low bq, low freq, many artifacts, many samples",UPN2_096,X,15841173,T,G,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn419Lys/c.1257T>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),3036,44,3116,"0,0141206675",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"28,6",14
"low bq, low freq, many artifacts, many samples",UPN2_097,X,15841173,T,G,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn419Lys/c.1257T>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),3438,40,3523,"0,0113539597",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"28,64",14
"low bq, low freq, many artifacts, many samples",UPN2_098,X,15841173,T,G,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn419Lys/c.1257T>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),1893,27,1936,"0,013946281",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"28,26","14,48"
"low bq, low freq, many artifacts, many samples",UPN2_100,X,15841173,T,G,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn419Lys/c.1257T>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),3845,57,3944,"0,0144523327",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"28,7",14
"low bq, low freq, many artifacts, many samples",UPN2_101,X,15841173,T,G,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn419Lys/c.1257T>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),1951,28,2007,"0,0139511709",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"28,62",14
"low bq, low freq, many artifacts, many samples",UPN2_102,X,15841173,T,G,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn419Lys/c.1257T>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),1778,30,1832,"0,0163755459",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"28,43",14
"low bq, low freq, many artifacts, many samples",UPN2_103,X,15841173,T,G,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn419Lys/c.1257T>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),4582,74,4704,"0,0157312925",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"28,32","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_104,X,15841173,T,G,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn419Lys/c.1257T>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),2086,22,2126,"0,0103480715",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"28,21","15,59"
"low bq, low freq, many artifacts, many samples",UPN2_105,X,15841173,T,G,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn419Lys/c.1257T>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),3571,64,3674,"0,017419706",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"28,44","14,11"
"low bq, low freq, many artifacts, many samples",UPN2_107,X,15841173,T,G,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn419Lys/c.1257T>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),3039,47,3113,"0,0150979762",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"28,65",14
"low bq, low freq, many artifacts, many samples",UPN2_108,X,15841173,T,G,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn419Lys/c.1257T>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),6755,104,6929,"0,0150093809",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"28,84",14
"low bq, low freq, many artifacts, many samples",UPN2_109,X,15841173,T,G,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn419Lys/c.1257T>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),3023,36,3089,"0,011654257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"28,7",14
"low bq, low freq, many artifacts",UPN2_111,X,15841173,T,G,missense_variant(MODERATE|MISSENSE|aaT/aaG|p.Asn419Lys/c.1257T>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),5608,82,5758,"0,0142410559",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,429,Tolerated,"28,48","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_043,X,15841174,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser420Thr/c.1258T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),5314,64,5414,"0,0118212043",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,141,Tolerated,"32,08","18,27"
"low bq, low freq, many artifacts, many samples",UPN2_044,X,15841174,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser420Thr/c.1258T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1866,20,1895,"0,0105540897",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,141,Tolerated,"32,08",21
"low bq, low freq, many artifacts, many samples",UPN2_045,X,15841174,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser420Thr/c.1258T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2238,24,2269,"0,0105773468",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,141,Tolerated,"31,81","20,79"
"low bq, low freq, many artifacts, many samples",UPN2_046,X,15841174,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser420Thr/c.1258T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4372,47,4434,"0,0105999098",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,141,Tolerated,32,"18,79"
"low bq, low freq, many artifacts, many samples",UPN2_056,X,15841174,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser420Thr/c.1258T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2842,30,2881,"0,010413051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,141,Tolerated,"31,75",21
"low bq, low freq, many artifacts, many samples",UPN2_057,X,15841174,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser420Thr/c.1258T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3601,46,3670,"0,0125340599",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,141,Tolerated,"31,65","19,7"
"low bq, low freq, many artifacts, many samples",UPN2_012,X,15841174,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser420Thr/c.1258T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2018,21,2049,"0,0102489019",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,141,Tolerated,"32,16","16,71"
"low bq, low freq, many artifacts",UPN2_091,X,15841174,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser420Thr/c.1258T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2133,25,2164,"0,0115526802",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,"0,141",Tolerated,"32,14","25,16"
"low bq, low freq, many artifacts",UPN2_068,X,15841174,T,A,missense_variant(MODERATE|MISSENSE|Tca/Aca|p.Ser420Thr/c.1258T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4466,46,4558,"0,0100921457",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,33",Neutral,141,Tolerated,"30,39","21,15"
"low bq, low freq, many artifacts, many samples",UPN2_070,X,15841174,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser420Ala/c.1258T>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),2985,47,3051,"0,0154047853",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,29,Damaging,"28,63","17,36"
"low bq, low freq, many artifacts, many samples",UPN2_075,X,15841174,T,G,missense_variant(MODERATE|MISSENSE|Tca/Gca|p.Ser420Ala/c.1258T>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),2252,28,2309,"0,0121264617",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,45",Neutral,29,Damaging,"29,27","16,93"
"low bq, low freq, many artifacts, many samples",UPN2_002,X,15841175,C,A,stop_gained(HIGH|NONSENSE|tCa/tAa|p.Ser420*/c.1259C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2928,37,2975,"0,0124369748",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,31","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_045,X,15841175,C,A,stop_gained(HIGH|NONSENSE|tCa/tAa|p.Ser420*/c.1259C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2229,24,2269,"0,0105773468",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,13","16,04"
"low bq, low freq, many artifacts, many samples",UPN2_006,X,15841175,C,A,stop_gained(HIGH|NONSENSE|tCa/tAa|p.Ser420*/c.1259C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),5117,57,5193,"0,0109763143",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,49","14,47"
"low bq, low freq, many artifacts, many samples",UPN2_051,X,15841175,C,A,stop_gained(HIGH|NONSENSE|tCa/tAa|p.Ser420*/c.1259C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4122,43,4181,"0,0102846209",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"29,86","16,12"
"low bq, low freq, many artifacts",UPN2_077,X,15841175,C,A,stop_gained(HIGH|NONSENSE|tCa/tAa|p.Ser420*/c.1259C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2318,25,2367,"0,0105618927",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"28,44","14,52"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_059,X,15841180,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser422Arg/c.1264A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),5206,56,5302,"0,0105620521",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,33,Damaging,"26,07","14,7"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,X,15841180,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser422Arg/c.1264A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1863,22,1902,"0,0115667718",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,33,Damaging,"25,75","14,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,X,15841180,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser422Arg/c.1264A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2013,24,2049,"0,0117130307",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,33,Damaging,"25,57","14,54"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_080,X,15841180,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser422Arg/c.1264A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1562,21,1589,"0,013215859",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,33,Damaging,"25,38",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,X,15841180,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser422Arg/c.1264A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2328,25,2381,"0,01049979",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,33,Damaging,"26,02","14,28"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,X,15841180,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser422Arg/c.1264A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4859,51,4950,"0,0103030303",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,33,Damaging,"25,88","14,14"
"low bq, bad alignment, low freq, many artifacts",UPN2_087,X,15841180,A,C,missense_variant(MODERATE|MISSENSE|Agc/Cgc|p.Ser422Arg/c.1264A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2997,31,3061,"0,0101274093",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,27",Neutral,33,Damaging,"26,41",14
"low bq, low freq, many artifacts",UPN2_024,X,15841180,A,T,missense_variant(MODERATE|MISSENSE|Agc/Tgc|p.Ser422Cys/c.1264A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),1435,20,1464,"0,0136612022",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-3,23",Deleterious,12,Damaging,"28,21","22,35"
"low bq, low freq, many artifacts, many samples",UPN2_059,X,15841185,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg423Ser/c.1269A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),5177,91,5296,"0,0171827795",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,92",Neutral,267,Tolerated,"27,83","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_060,X,15841185,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg423Ser/c.1269A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1615,28,1656,"0,0169082126",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,92",Neutral,267,Tolerated,"27,91","14,79"
"low bq, low freq, many artifacts, many samples",UPN2_061,X,15841185,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg423Ser/c.1269A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3576,64,3661,"0,0174815624",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,92",Neutral,267,Tolerated,"27,91","14,83"
"low bq, low freq, many artifacts, many samples",UPN2_062,X,15841185,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg423Ser/c.1269A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1615,26,1654,"0,015719468",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,92",Neutral,267,Tolerated,"27,92",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,X,15841185,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg423Ser/c.1269A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1864,24,1897,"0,0126515551",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,92",Neutral,267,Tolerated,"26,99",14
"low bq, low freq, many artifacts, many samples",UPN2_064,X,15841185,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg423Ser/c.1269A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),7153,118,7307,"0,0161488983",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,92",Neutral,267,Tolerated,"27,91","14,45"
"low bq, low freq, many artifacts, many samples",UPN2_065,X,15841185,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg423Ser/c.1269A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),6609,103,6741,"0,0152796321",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,92",Neutral,267,Tolerated,"28,19","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_066,X,15841185,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg423Ser/c.1269A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3188,57,3259,"0,0174900276",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,92",Neutral,267,Tolerated,"27,67","14,51"
"low bq, low freq, many artifacts, many samples",UPN2_067,X,15841185,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg423Ser/c.1269A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4302,51,4378,"0,0116491549",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,92",Neutral,267,Tolerated,"28,1","14,14"
"low bq, low freq, many artifacts, many samples",UPN2_068,X,15841185,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg423Ser/c.1269A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4445,74,4540,"0,0162995595",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,92",Neutral,267,Tolerated,"27,82","14,42"
"low bq, low freq, many artifacts, many samples",UPN2_069,X,15841185,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg423Ser/c.1269A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2556,44,2612,"0,0168453292",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,92",Neutral,267,Tolerated,"27,87","14,57"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_070,X,15841185,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg423Ser/c.1269A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3009,45,3067,"0,0146723182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,92",Neutral,267,Tolerated,"26,93","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_072,X,15841185,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg423Ser/c.1269A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2197,30,2238,"0,0134048257",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,92",Neutral,267,Tolerated,"28,11","14,43"
"low bq, low freq, many artifacts, many samples",UPN2_073,X,15841185,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg423Ser/c.1269A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2432,25,2468,"0,0101296596",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,92",Neutral,267,Tolerated,"28,14","14,28"
"low bq, low freq, many artifacts, many samples",UPN2_074,X,15841185,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg423Ser/c.1269A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3238,45,3309,"0,0135992747",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,92",Neutral,267,Tolerated,"28,13","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_075,X,15841185,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg423Ser/c.1269A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2274,37,2327,"0,0159003008",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,92",Neutral,267,Tolerated,"27,15","14,68"
"low bq, low freq, many artifacts, many samples",UPN2_076,X,15841185,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg423Ser/c.1269A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2262,23,2297,"0,0100130605",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,92",Neutral,267,Tolerated,"27,76",14
"low bq, low freq, many artifacts, many samples",UPN2_078,X,15841185,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg423Ser/c.1269A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1996,38,2047,"0,0185637518",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,92",Neutral,267,Tolerated,"27,79","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_079,X,15841185,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg423Ser/c.1269A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2159,32,2206,"0,014505893",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,92",Neutral,267,Tolerated,"27,9","14,81"
"low bq, low freq, many artifacts, many samples",UPN2_080,X,15841185,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg423Ser/c.1269A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1561,21,1587,"0,0132325142",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,92",Neutral,267,Tolerated,"27,27",14
"low bq, low freq, many artifacts, many samples",UPN2_081,X,15841185,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg423Ser/c.1269A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4489,63,4578,"0,0137614679",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,92",Neutral,267,Tolerated,"28,07","14,32"
"low bq, low freq, many artifacts, many samples",UPN2_082,X,15841185,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg423Ser/c.1269A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),6016,88,6132,"0,0143509459",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,92",Neutral,267,Tolerated,"28,04","14,66"
"low bq, low freq, many artifacts, many samples",UPN2_083,X,15841185,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg423Ser/c.1269A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2330,30,2375,"0,0126315789",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,92",Neutral,267,Tolerated,"27,66",14
"low bq, low freq, many artifacts, many samples",UPN2_084,X,15841185,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg423Ser/c.1269A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3250,55,3332,"0,0165066026",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,92",Neutral,267,Tolerated,"27,82","15,82"
"low bq, low freq, many artifacts, many samples",UPN2_085,X,15841185,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg423Ser/c.1269A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2816,45,2874,"0,01565762",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,92",Neutral,267,Tolerated,"27,66",14
"low bq, low freq, many artifacts, many samples",UPN2_086,X,15841185,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg423Ser/c.1269A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4844,74,4939,"0,01498279",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,92",Neutral,267,Tolerated,"27,83","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_087,X,15841185,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg423Ser/c.1269A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2991,42,3052,"0,0137614679",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,92",Neutral,267,Tolerated,"28,03","14,76"
"low bq, low freq, many artifacts",UPN2_088,X,15841185,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg423Ser/c.1269A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4930,80,5027,"0,0159140641",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,92",Neutral,267,Tolerated,"27,99","14,48"
"low bq, low freq, many artifacts",UPN2_006,X,15841186,G,A,missense_variant(MODERATE|MISSENSE|Gga/Aga|p.Gly424Arg/c.1270G>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),5117,54,5187,"0,010410642",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,"0,009",Damaging,"32,52","27,19"
"low bq, low freq, many artifacts",UPN2_063,X,15841186,G,A,missense_variant(MODERATE|MISSENSE|Gga/Aga|p.Gly424Arg/c.1270G>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1866,22,1897,"0,0115972588",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,06",Neutral,"0,009",Damaging,"30,11","27,45"
"low freq, many artifacts",UPN2_056,X,15841187,GA,G,frameshift_variant(HIGH||aga/|p.Arg425fs/c.1273delA|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G|INFO_REALIGN_3_PRIME),2815,39,2881,"0,0135369663",0,0,0,1,1,0,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"30,92",NA
"low bq, many samples",UPN2_059,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),5071,140,5254,"0,0266463647",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"27,63","14,69"
"low bq, many samples",UPN2_060,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1583,55,1647,"0,0333940498",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"27,58","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_092,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2159,27,2192,"0,0123175182",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"28,85","14,52"
"low bq, many samples",UPN2_061,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3492,102,3617,"0,0282001659",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"27,53","14,84"
"low bq, many samples",UPN2_062,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1566,55,1642,"0,0334957369",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"27,95","14,13"
"low bq, many samples",UPN2_063,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1820,45,1881,"0,023923445",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"27,41","15,38"
"low bq, many samples",UPN2_064,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),6989,193,7234,"0,0266795687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"27,63","14,9"
"low bq, many samples",UPN2_065,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),6454,179,6685,"0,026776365",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"28,03","14,62"
"low bq, many samples",UPN2_066,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3093,104,3224,"0,0322580645",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"27,83","14,57"
"low bq, many samples",UPN2_067,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4204,99,4339,"0,0228163171",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"27,86","14,46"
"low bq, many samples",UPN2_068,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4355,119,4503,"0,0264268266",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"27,69","14,53"
"low bq, many samples",UPN2_069,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2503,62,2582,"0,0240123935",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"27,91","14,4"
"low bq, many samples",UPN2_070,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2920,93,3030,"0,0306930693",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"27,79","14,76"
"low bq, low freq, many artifacts, many samples",UPN2_071,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1346,30,1383,"0,021691974",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"27,97","14,6"
"low bq, many samples",UPN2_072,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2143,54,2212,"0,0244122966",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"27,76","14,13"
"low bq, many samples",UPN2_073,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2352,58,2437,"0,0237997538",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"27,87","14,34"
"low bq, many samples",UPN2_074,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3164,97,3279,"0,0295821897",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"27,89","14,59"
"low bq, many samples",UPN2_075,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2240,56,2304,"0,0243055556",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"27,59","14,45"
"low bq, many samples",UPN2_076,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2196,64,2278,"0,02809482",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"27,7","14,7"
"low bq, many samples",UPN2_077,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2261,68,2345,"0,0289978678",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"27,74","15,1"
"low bq, many samples",UPN2_078,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1935,72,2026,"0,0355380059",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"27,72","14,35"
"low bq, many samples",UPN2_079,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2112,49,2178,"0,0224977043",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"27,63","14,41"
"low bq, many samples",UPN2_080,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1526,36,1577,"0,0228281547",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"27,71","14,56"
"low bq, many samples",UPN2_081,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4370,129,4535,"0,0284454245",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"27,8","14,81"
"low bq, many samples",UPN2_082,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),5864,170,6066,"0,0280250577",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"27,94","14,56"
"low bq, many samples",UPN2_083,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2275,70,2353,"0,0297492563",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"27,36","14,49"
"low bq, many samples",UPN2_084,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3192,85,3298,"0,0257731959",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"27,55","14,55"
"low bq, many samples",UPN2_085,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2739,83,2843,"0,0291945128",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"27,78","14,96"
"low bq, many samples",UPN2_086,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4729,126,4889,"0,0257721415",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"27,66","14,78"
"low bq, many samples",UPN2_087,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2926,84,3031,"0,0277136259",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"27,86","15,14"
"low bq, many samples",UPN2_088,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4799,149,4976,"0,0299437299",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"27,79","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_095,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3960,45,4017,"0,0112023898",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"28,64","14,29"
"low bq, low freq, many artifacts, many samples",UPN2_096,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3056,37,3106,"0,0119124276",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"28,8",14
"low bq, low freq, many artifacts, many samples",UPN2_101,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1966,20,1997,"0,0100150225",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"28,7",14
"low bq, low freq, many artifacts, many samples",UPN2_102,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1799,20,1826,"0,0109529025",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"28,39","14,35"
"low bq, low freq, many artifacts, many samples",UPN2_103,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4612,52,4688,"0,0110921502",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"28,49","14,13"
"low bq, low freq, many artifacts, many samples",UPN2_104,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2082,23,2117,"0,0108644308",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"28,67","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_105,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3600,48,3665,"0,0130968622",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"28,7",14
"low bq, low freq, many artifacts, many samples",UPN2_106,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2888,35,2939,"0,0119088125",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"28,88","14,37"
"low bq, low freq, many artifacts, many samples",UPN2_108,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),6811,74,6909,"0,0107106672",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"28,88","14,64"
"low bq, low freq, many artifacts, many samples",UPN2_109,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3032,33,3083,"0,0107038599",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"28,72",14
"low bq, low freq, many artifacts, many samples",UPN2_110,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2179,26,2212,"0,0117540687",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"28,82",14
"low bq, low freq, many artifacts",UPN2_111,X,15841191,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg425Ser/c.1275A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),5649,59,5740,"0,0102787456",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,6,Damaging,"28,74","14,58"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_060,X,15841192,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn426His/c.1276A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1605,21,1645,"0,0127659574",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,78,Tolerated,"26,9",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_063,X,15841192,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn426His/c.1276A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1839,20,1875,"0,0106666667",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,78,Tolerated,26,"14,65"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_070,X,15841192,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn426His/c.1276A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2957,32,3025,"0,0105785124",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,78,Tolerated,"25,89","14,81"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_079,X,15841192,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn426His/c.1276A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2130,22,2175,"0,0101149425",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,78,Tolerated,"26,96","14,32"
"low bq, bad alignment, low freq, many artifacts",UPN2_085,X,15841192,A,C,missense_variant(MODERATE|MISSENSE|Aat/Cat|p.Asn426His/c.1276A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2762,32,2825,"0,0113274336",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,78",Neutral,78,Tolerated,"26,77",14
"low freq, many artifacts",UPN2_054,X,15841192,A,G,missense_variant(MODERATE|MISSENSE|Aat/Gat|p.Asn426Asp/c.1276A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),2884,31,2945,"0,0105263158",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,34",Neutral,1,Tolerated,"29,26",33
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_059,X,15841193,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn426Thr/c.1277A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),5100,75,5232,"0,0143348624",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,294,Tolerated,"24,91","14,63"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_060,X,15841193,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn426Thr/c.1277A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1602,25,1636,"0,0152811736",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,294,Tolerated,"24,91","14,72"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_061,X,15841193,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn426Thr/c.1277A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3502,55,3594,"0,0153032832",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,294,Tolerated,"25,02",14
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_062,X,15841193,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn426Thr/c.1277A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1583,22,1632,"0,0134803922",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,294,Tolerated,"24,94","14,59"
"low bq, bad alignment, many samples",UPN2_063,X,15841193,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn426Thr/c.1277A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1812,46,1875,"0,0245333333",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,294,Tolerated,"24,08","14,85"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_064,X,15841193,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn426Thr/c.1277A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),6984,145,7201,"0,0201360922",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,294,Tolerated,"24,97","14,37"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_065,X,15841193,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn426Thr/c.1277A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),6508,107,6661,"0,0160636541",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,294,Tolerated,"25,36","14,41"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_066,X,15841193,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn426Thr/c.1277A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3115,60,3211,"0,0186857677",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,294,Tolerated,"25,3","14,23"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_067,X,15841193,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn426Thr/c.1277A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4204,64,4314,"0,0148354196",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,294,Tolerated,"25,34","14,97"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_068,X,15841193,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn426Thr/c.1277A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4359,81,4484,"0,0180642284",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,294,Tolerated,"24,73","14,22"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_069,X,15841193,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn426Thr/c.1277A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2504,37,2569,"0,0144024912",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,294,Tolerated,"25,06","14,7"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_070,X,15841193,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn426Thr/c.1277A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2936,62,3017,"0,0205502154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,294,Tolerated,"24,15","15,08"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_071,X,15841193,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn426Thr/c.1277A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1340,24,1374,"0,0174672489",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,294,Tolerated,"25,45","15,21"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_072,X,15841193,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn426Thr/c.1277A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2158,32,2205,"0,0145124717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,294,Tolerated,"25,16","14,62"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_073,X,15841193,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn426Thr/c.1277A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2363,42,2427,"0,0173053152",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,294,Tolerated,"24,88","15,36"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_074,X,15841193,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn426Thr/c.1277A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3194,46,3263,"0,0140974563",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,294,Tolerated,"24,88","14,67"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_075,X,15841193,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn426Thr/c.1277A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2232,39,2297,"0,0169786678",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,294,Tolerated,"24,35","14,46"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_076,X,15841193,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn426Thr/c.1277A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2211,42,2272,"0,0184859155",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,294,Tolerated,"24,66","14,64"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_077,X,15841193,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn426Thr/c.1277A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2286,35,2338,"0,0149700599",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,294,Tolerated,"24,63","15,51"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_078,X,15841193,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn426Thr/c.1277A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1946,39,2019,"0,0193164933",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,294,Tolerated,"24,41","14,69"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_079,X,15841193,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn426Thr/c.1277A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2119,41,2173,"0,0188679245",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,294,Tolerated,"25,09","14,32"
"low bq, bad alignment, many samples",UPN2_080,X,15841193,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn426Thr/c.1277A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1516,40,1572,"0,0254452926",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,294,Tolerated,"24,45","14,32"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_081,X,15841193,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn426Thr/c.1277A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4406,66,4516,"0,0146147033",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,294,Tolerated,"25,21","14,48"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_082,X,15841193,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn426Thr/c.1277A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),5896,98,6049,"0,016201025",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,294,Tolerated,"25,22","14,2"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_083,X,15841193,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn426Thr/c.1277A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2271,50,2342,"0,0213492741",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,294,Tolerated,"24,73","14,66"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_084,X,15841193,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn426Thr/c.1277A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3176,58,3283,"0,0176667682",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,294,Tolerated,"24,57","14,57"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_085,X,15841193,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn426Thr/c.1277A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2743,47,2818,"0,0166784954",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,294,Tolerated,"24,68","14,43"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_086,X,15841193,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn426Thr/c.1277A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4744,77,4874,"0,0157981124",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,294,Tolerated,"24,75","14,64"
"low bq, bad alignment, low freq, many artifacts, many samples",UPN2_087,X,15841193,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn426Thr/c.1277A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2942,60,3019,"0,0198741305",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,294,Tolerated,"25,26","14,52"
"low bq, bad alignment, low freq, many artifacts",UPN2_088,X,15841193,A,C,missense_variant(MODERATE|MISSENSE|aAt/aCt|p.Asn426Thr/c.1277A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4840,70,4959,"0,0141157491",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,65",Neutral,294,Tolerated,"25,18","15,07"
"low bq, low freq, many artifacts, many samples",UPN2_001,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1333,23,1358,"0,0169366716",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"30,1","16,43"
"low bq, many samples",UPN2_014,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3319,90,3416,"0,0263466042",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"31,28","16,86"
"low bq, many samples",UPN2_015,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4950,125,5083,"0,0245917765",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"31,22","16,99"
"low bq, many samples",UPN2_016,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2307,60,2371,"0,0253057782",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"30,93","15,73"
"low bq, low freq, many artifacts, many samples",UPN2_017,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1295,24,1319,"0,0181956027",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"31,1","16,33"
"low bq, many samples",UPN2_018,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2499,79,2591,"0,0304901582",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"31,4","17,58"
"low bq, low freq, many artifacts, many samples",UPN2_019,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2776,58,2838,"0,0204369274",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"31,43","16,33"
"low bq, many samples",UPN2_020,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1358,35,1399,"0,0250178699",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"31,36","16,14"
"low bq, many samples",UPN2_021,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2468,60,2534,"0,0236779795",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"31,39","16,88"
"low bq, low freq, many artifacts, many samples",UPN2_002,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2891,55,2950,"0,0186440678",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"30,38",18
"low bq, many samples",UPN2_022,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),6932,192,7138,"0,0268982908",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"31,36","16,99"
"low bq, many samples",UPN2_023,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3215,87,3307,"0,0263078319",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"31,23","16,92"
"low bq, many samples",UPN2_041,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),6218,212,6433,"0,0329550754",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"30,43","17,26"
"low bq, many samples",UPN2_024,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1411,40,1455,"0,0274914089",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"31,38","15,27"
"low bq, many samples",UPN2_025,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),8702,217,8929,"0,0243028335",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"31,23","15,79"
"low bq, many samples",UPN2_026,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),6877,179,7064,"0,0253397508",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"31,49","16,44"
"low bq, low freq, many artifacts, many samples",UPN2_027,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4150,84,4249,"0,0197693575",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"31,33","17,24"
"low bq, low freq, many artifacts, many samples",UPN2_089,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4169,57,4245,"0,0134275618",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"31,5",14
"low bq, many samples",UPN2_042,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),9061,327,9424,"0,0346986418",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"30,71","16,87"
"low bq, many samples",UPN2_028,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3308,76,3387,"0,0224387363",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"31,33","16,95"
"low bq, many samples",UPN2_043,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),5163,182,5358,"0,0339678985",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"30,51","17,03"
"low bq, many samples",UPN2_044,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1816,58,1874,"0,0309498399",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"30,54","15,84"
"low bq, many samples",UPN2_029,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2690,75,2771,"0,0270660411",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"31,36","15,84"
"low bq, many samples",UPN2_030,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3909,107,4022,"0,0266036798",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"31,39","16,76"
"low bq, many samples",UPN2_031,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4779,125,4908,"0,0254686227",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"31,15","15,48"
"low bq, many samples",UPN2_005,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),815,20,839,"0,0238379023",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"29,73","17,35"
"low bq, many samples",UPN2_045,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2177,64,2243,"0,0285332144",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"30,5","16,53"
"low bq, low freq, many artifacts, many samples",UPN2_032,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2267,48,2318,"0,0207075065",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"31,2","15,08"
"low bq, many samples",UPN2_046,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4191,134,4332,"0,0309325946",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"30,58","16,72"
"low bq, many samples",UPN2_033,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2553,75,2630,"0,0285171103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"31,21","16,36"
"low bq, low freq, many artifacts, many samples",UPN2_034,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1130,21,1151,"0,0182450043",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"31,55","16,33"
"low bq, many samples",UPN2_047,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),5394,178,5588,"0,0318539728",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"30,63","17,71"
"low bq, many samples",UPN2_048,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),6529,247,6802,"0,0363128492",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"30,43","17,59"
"low bq, many samples",UPN2_035,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),9109,242,9384,"0,0257885763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"31,14","16,01"
"low bq, many samples",UPN2_036,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4546,146,4699,"0,0310704405",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"31,36","17,79"
"low bq, low freq, many artifacts, many samples",UPN2_006,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),5036,98,5143,"0,0190550262",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"30,21","16,99"
"low bq, many samples",UPN2_049,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3346,117,3470,"0,0337175793",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"30,61","17,12"
"low bq, many samples",UPN2_050,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2895,84,2986,"0,0281312793",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"30,4","16,86"
"low bq, low freq, many artifacts, many samples",UPN2_037,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),7766,171,7975,"0,0214420063",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"31,52","15,88"
"low bq, many samples",UPN2_051,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3985,142,4133,"0,0343576095",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"30,51","16,24"
"low bq, many samples",UPN2_052,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4894,167,5074,"0,0329128892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"30,71","17,19"
"low bq, many samples",UPN2_038,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),5650,131,5796,"0,0226017943",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"31,42","15,88"
"low bq, many samples",UPN2_039,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),6671,156,6839,"0,0228103524",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"31,36","17,1"
"low bq, many samples",UPN2_053,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),7971,279,8272,"0,0337282398",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"30,53","18,27"
"low bq, many samples",UPN2_054,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2835,97,2940,"0,0329931973",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"30,48","17,2"
"low bq, low freq, many artifacts, many samples",UPN2_007,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4238,91,4345,"0,0209436133",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"30,28","16,51"
"low bq, many samples",UPN2_008,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),5822,140,5970,"0,0234505863",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"30,33","17,78"
"low bq, low freq, many artifacts, many samples",UPN2_009,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),8911,161,9090,"0,0177117712",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"30,22","15,49"
"low bq, low freq, many artifacts, many samples",UPN2_010,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),6808,151,6969,"0,0216673841",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"30,06","17,14"
"low bq, low freq, many artifacts, many samples",UPN2_011,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),6233,139,6376,"0,0218005019",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"30,27","16,42"
"low bq, many samples",UPN2_055,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),8401,313,8732,"0,0358451672",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"30,51","17,1"
"low bq, many samples",UPN2_056,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2771,88,2863,"0,0307369892",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"30,55","16,6"
"low bq, many samples",UPN2_057,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3460,122,3591,"0,0339738234",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"30,36","16,48"
"low bq, many samples",UPN2_058,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4420,147,4584,"0,0320680628",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"30,39","16,48"
"low bq, many samples",UPN2_059,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4983,156,5180,"0,0301158301",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"28,97","15,72"
"low bq, low freq, many artifacts, many samples",UPN2_012,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2004,29,2035,"0,0142506143",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"30,12","14,45"
"low bq, many samples",UPN2_060,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1559,36,1608,"0,0223880597",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"29,01","14,5"
"low bq, many samples",UPN2_040,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),7070,173,7260,"0,0238292011",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"31,16","17,5"
"low bq, many samples",UPN2_013,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1037,27,1066,"0,0253283302",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"30,51","17,52"
"low bq, low freq, many artifacts, many samples",UPN2_093,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3002,33,3041,"0,0108516935",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"31,54","16,42"
"low bq, many samples",UPN2_061,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3465,103,3581,"0,0287629154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"29,12",15
"low bq, many samples",UPN2_062,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1575,46,1628,"0,0282555283",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"29,03","17,09"
"low bq, many samples",UPN2_063,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1779,56,1853,"0,0302212628",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"28,47","15,14"
"low bq, many samples",UPN2_064,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),6894,200,7131,"0,0280465573",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"28,97","15,62"
"low bq, many samples",UPN2_065,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),6377,218,6626,"0,0329006942",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"29,02","15,43"
"low bq, many samples",UPN2_066,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3073,102,3192,"0,0319548872",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"29,02","14,38"
"low bq, many samples",UPN2_067,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4131,136,4294,"0,0316721006",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"28,97","14,79"
"low bq, many samples",UPN2_068,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4311,120,4463,"0,0268877437",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"29,1","15,37"
"low bq, many samples",UPN2_069,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2457,71,2553,"0,0278104191",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"29,15","15,42"
"low bq, many samples",UPN2_070,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2890,93,3003,"0,030969031",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"28,46","16,29"
"low bq, many samples",UPN2_071,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1310,38,1359,"0,0279617366",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"29,27",17
"low bq, many samples",UPN2_072,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2108,68,2192,"0,0310218978",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"28,68","15,57"
"low bq, many samples",UPN2_073,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2332,63,2410,"0,0261410788",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"28,88","15,51"
"low bq, many samples",UPN2_074,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3117,90,3234,"0,0278293135",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,29,"14,94"
"low bq, many samples",UPN2_075,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2207,70,2293,"0,030527693",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"28,39","15,13"
"low bq, many samples",UPN2_076,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2166,75,2256,"0,0332446809",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"28,8","15,24"
"low bq, many samples",UPN2_077,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2255,61,2329,"0,0261914985",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"28,93","15,84"
"low bq, many samples",UPN2_078,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1941,56,2007,"0,0279023418",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"29,08","15,14"
"low bq, many samples",UPN2_079,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2066,65,2145,"0,0303030303",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"29,05","15,32"
"low bq, many samples",UPN2_080,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1521,42,1569,"0,0267686424",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"28,31","15,26"
"low bq, many samples",UPN2_081,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4330,134,4494,"0,0298175345",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"28,98","14,97"
"low bq, many samples",UPN2_082,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),5816,173,6019,"0,028742316",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"28,97","16,15"
"low bq, low freq, many artifacts, many samples",UPN2_083,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2266,50,2331,"0,0214500215",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"28,9","14,8"
"low bq, many samples",UPN2_084,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3146,94,3261,"0,0288255136",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"28,97","15,56"
"low bq, many samples",UPN2_085,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2695,87,2802,"0,0310492505",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"29,05","15,3"
"low bq, many samples",UPN2_086,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4663,138,4837,"0,0285300806",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"28,97","15,4"
"low bq, many samples",UPN2_087,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2876,98,3004,"0,0326231691",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"28,89","15,87"
"low bq, many samples",UPN2_088,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),4740,157,4925,"0,0318781726",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"29,06","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_095,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3934,49,3995,"0,0122653317",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"31,32","14,65"
"low bq, low freq, many artifacts, many samples",UPN2_096,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3042,40,3092,"0,0129366106",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"31,43","15,9"
"low bq, low freq, many artifacts, many samples",UPN2_097,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3446,37,3489,"0,0106047578",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"31,54","14,49"
"low bq, low freq, many artifacts, many samples",UPN2_100,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3865,42,3914,"0,0107307103",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"31,3","17,12"
"low bq, low freq, many artifacts, many samples",UPN2_101,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1952,25,1981,"0,0126198889",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"31,47","15,72"
"low bq, low freq, many artifacts, many samples",UPN2_102,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1793,26,1824,"0,014254386",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"31,36",14
"low bq, low freq, many artifacts, many samples",UPN2_106,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2880,34,2927,"0,0116159891",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"31,44",15
"low bq, low freq, many artifacts, many samples",UPN2_107,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),3033,35,3081,"0,0113599481",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"31,22","14,71"
"low bq, low freq, many artifacts",UPN2_108,X,15841194,T,A,missense_variant(MODERATE|MISSENSE|aaT/aaA|p.Asn426Lys/c.1278T>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),6766,82,6862,"0,0119498688",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,03",Neutral,"0,74",Tolerated,"31,46","14,9"
"low bq, low freq, many artifacts",UPN2_006,X,15841205,G,T,missense_variant(MODERATE|MISSENSE|aGc/aTc|p.Ser430Ile/c.1289G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),2582,28,2614,"0,0107115532",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,65",Deleterious,31,Damaging,"34,33","23,39"
many samples,UPN2_001,X,15841230,C,+AGCCGG,disruptive_inframe_insertion(MODERATE||cgc/cgGAGCCGc|p.Arg448_Arg449insSerArg/c.1338_1343dupGAGCCG|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|+AGCCGG|INFO_REALIGN_3_PRIME),687,641,689,"0,9303338171",0,0,1,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"35,09",NA
many samples,UPN2_010,X,15841230,C,+AGCCGG,disruptive_inframe_insertion(MODERATE||cgc/cgGAGCCGc|p.Arg448_Arg449insSerArg/c.1338_1343dupGAGCCG|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|+AGCCGG|INFO_REALIGN_3_PRIME),3506,1655,3520,"0,4701704545",0,0,1,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,84",NA
many samples,UPN2_063,X,15841230,C,+AGCCGG,disruptive_inframe_insertion(MODERATE||cgc/cgGAGCCGc|p.Arg448_Arg449insSerArg/c.1338_1343dupGAGCCG|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|+AGCCGG|INFO_REALIGN_3_PRIME),954,871,963,"0,9044652129",0,0,1,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,59",NA
many samples,UPN2_070,X,15841230,C,+AGCCGG,disruptive_inframe_insertion(MODERATE||cgc/cgGAGCCGc|p.Arg448_Arg449insSerArg/c.1338_1343dupGAGCCG|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|+AGCCGG|INFO_REALIGN_3_PRIME),1564,1431,1574,"0,9091486658",0,0,1,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,69",NA
many samples,UPN2_075,X,15841230,C,+AGCCGG,disruptive_inframe_insertion(MODERATE||cgc/cgGAGCCGc|p.Arg448_Arg449insSerArg/c.1338_1343dupGAGCCG|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|+AGCCGG|INFO_REALIGN_3_PRIME),1189,1077,1193,"0,9027661358",0,0,1,0,0,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,46",NA
"low freq, neutral effect",UPN2_046,X,15841232,G,A,missense_variant(MODERATE|MISSENSE|aGc/aAc|p.Ser439Asn/c.1316G>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2220,24,2244,"0,0106951872",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,52",Neutral,"0,975",Tolerated,"35,13","34,58"
"low bq, low freq, many artifacts",UPN2_041,X,15841234,C,T,missense_variant(MODERATE|MISSENSE|Cgg/Tgg|p.Arg440Trp/c.1318C>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),3224,45,3276,"0,0137362637",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,84",Deleterious,"0,013",Damaging,"33,8","29,47"
"low freq, neutral effect",UPN2_044,X,15841247,G,A,missense_variant(MODERATE|MISSENSE|cGg/cAg|p.Arg444Gln/c.1331G>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),929,29,961,"0,0301768991",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,17",Neutral,"0,077",Tolerated,"34,09","35,07"
"low freq, neutral effect",UPN2_081,X,15841253,G,A,missense_variant(MODERATE|MISSENSE|cGg/cAg|p.Arg446Gln/c.1337G>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),2305,24,2333,"0,0102871839",0,0,0,0,1,0,0,1,2,0,NO,NO,NO,O,NO,rs375322183,NO,NO,NO,NO,"-0,97",Neutral,"0,349",Tolerated,"33,64","35,08"
"low freq, neutral effect",UPN2_044,X,15841258,C,A,missense_variant(MODERATE|MISSENSE|Cgc/Agc|p.Arg448Ser/c.1342C>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),919,39,961,"0,0405827263",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,74",Neutral,"0,386",Tolerated,"34,67","35,51"
"low freq, many artifacts",UPN2_027,X,15841267,C,T,missense_variant(MODERATE|MISSENSE|Cgc/Tgc|p.Arg451Cys/c.1351C>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),2149,22,2181,"0,010087116",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,66",Deleterious,"0,017",Damaging,"35,46","32,73"
"low freq, many artifacts",UPN2_056,X,15841268,G,A,missense_variant(MODERATE|MISSENSE|cGc/cAc|p.Arg451His/c.1352G>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1498,20,1520,"0,0131578947",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,3",Neutral,"0,474",Tolerated,"35,04","35,55"
"low freq, many artifacts",UPN2_005,X,15841283,A,C,missense_variant(MODERATE|MISSENSE|cAa/cCa|p.Gln456Pro/c.1367A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1554,28,1588,"0,0176322418",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,"0,019",Damaging,"35,53","34,93"
"low freq, many artifacts",UPN2_008,X,15841283,A,C,missense_variant(MODERATE|MISSENSE|cAa/cCa|p.Gln456Pro/c.1367A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),9227,127,9392,"0,0135221465",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,"0,019",Damaging,"35,64","35,6"
"low freq, many artifacts",UPN2_011,X,15841283,A,C,missense_variant(MODERATE|MISSENSE|cAa/cCa|p.Gln456Pro/c.1367A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),11801,228,12095,"0,0188507648",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,"0,019",Damaging,"35,58","35,14"
"low freq, many artifacts",UPN2_090,X,15841283,A,C,missense_variant(MODERATE|MISSENSE|cAa/cCa|p.Gln456Pro/c.1367A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3837,69,3931,"0,0175527856",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,"0,019",Damaging,"35,83","34,81"
"low freq, many artifacts",UPN2_059,X,15841283,A,C,missense_variant(MODERATE|MISSENSE|cAa/cCa|p.Gln456Pro/c.1367A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3092,33,3150,"0,0104761905",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,"0,019",Damaging,"35,46","35,64"
"low freq, many artifacts",UPN2_013,X,15841283,A,C,missense_variant(MODERATE|MISSENSE|cAa/cCa|p.Gln456Pro/c.1367A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1798,30,1836,"0,0163398693",0,0,0,0,1,1,0,1,3,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,53",Neutral,"0,019",Damaging,"35,66",35
"low freq, neutral effect",UPN2_056,X,15841313,G,A,missense_variant(MODERATE|MISSENSE|aGg/aAg|p.Arg466Lys/c.1397G>A|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|A),1493,23,1520,"0,0151315789",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,15",Neutral,"0,195",Tolerated,"35,35","35,83"
"low freq, many artifacts",UPN2_006,X,15841333,G,C,missense_variant(MODERATE|MISSENSE|Gac/Cac|p.Asp473His/c.1417G>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1339,22,1363,"0,0161408657",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,57",Neutral,0,Damaging,"35,63","35,82"
"low bq, low freq, many artifacts, many samples",UPN2_060,X,15841334,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp473Ala/c.1418A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4310,49,4385,"0,0111744584",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,0,Damaging,"29,55","15,18"
"low bq, low freq, many artifacts, many samples",UPN2_061,X,15841334,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp473Ala/c.1418A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),11870,175,12103,"0,014459225",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,0,Damaging,"28,9","15,25"
"low bq, low freq, many artifacts, many samples",UPN2_062,X,15841334,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp473Ala/c.1418A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),5729,101,5850,"0,0172649573",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,0,Damaging,"28,93","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_063,X,15841334,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp473Ala/c.1418A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),5479,73,5572,"0,0131012204",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,0,Damaging,"29,29","15,29"
"low bq, low freq, many artifacts, many samples",UPN2_065,X,15841334,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp473Ala/c.1418A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2715,44,2770,"0,0158844765",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,0,Damaging,"29,39","15,59"
"low bq, low freq, many artifacts, many samples",UPN2_066,X,15841334,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp473Ala/c.1418A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),7662,102,7796,"0,0130836326",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,0,Damaging,"29,55","15,67"
"low bq, low freq, many artifacts, many samples",UPN2_067,X,15841334,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp473Ala/c.1418A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),9967,122,10122,"0,012052954",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,0,Damaging,"29,87","14,75"
"low bq, low freq, many artifacts, many samples",UPN2_068,X,15841334,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp473Ala/c.1418A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),14349,236,14644,"0,0161158154",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,0,Damaging,"28,95","14,93"
"low bq, low freq, many artifacts, many samples",UPN2_069,X,15841334,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp473Ala/c.1418A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),6720,104,6848,"0,0151869159",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,0,Damaging,"29,19","14,98"
"low bq, low freq, many artifacts, many samples",UPN2_070,X,15841334,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp473Ala/c.1418A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),8961,145,9139,"0,0158660685",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,0,Damaging,"28,75","15,99"
"low bq, low freq, many artifacts, many samples",UPN2_071,X,15841334,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp473Ala/c.1418A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3282,50,3340,"0,0149700599",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,0,Damaging,"29,2","15,52"
"low bq, low freq, many artifacts, many samples",UPN2_072,X,15841334,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp473Ala/c.1418A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2195,23,2228,"0,0103231598",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,0,Damaging,"28,89","14,3"
"low bq, low freq, many artifacts, many samples",UPN2_074,X,15841334,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp473Ala/c.1418A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),6546,92,6657,"0,0138200391",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,0,Damaging,"29,5","15,46"
"low bq, low freq, many artifacts, many samples",UPN2_075,X,15841334,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp473Ala/c.1418A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),5519,85,5624,"0,015113798",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,0,Damaging,"29,75","14,4"
"low bq, low freq, many artifacts, many samples",UPN2_076,X,15841334,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp473Ala/c.1418A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),5530,101,5661,"0,0178413708",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,0,Damaging,"28,91","15,66"
"low bq, low freq, many artifacts, many samples",UPN2_077,X,15841334,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp473Ala/c.1418A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),6723,94,6842,"0,0137386729",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,0,Damaging,"29,06","14,91"
"low bq, low freq, many artifacts, many samples",UPN2_078,X,15841334,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp473Ala/c.1418A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),5587,86,5691,"0,0151115797",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,0,Damaging,"28,55","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_079,X,15841334,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp473Ala/c.1418A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),6080,81,6183,"0,0131004367",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,0,Damaging,"29,26","15,77"
"low bq, low freq, many artifacts, many samples",UPN2_080,X,15841334,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp473Ala/c.1418A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2447,35,2494,"0,0140336808",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,0,Damaging,"29,15","14,97"
"low bq, low freq, many artifacts, many samples",UPN2_082,X,15841334,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp473Ala/c.1418A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),11300,143,11482,"0,0124542763",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,0,Damaging,"29,66","15,04"
"low bq, low freq, many artifacts, many samples",UPN2_083,X,15841334,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp473Ala/c.1418A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),6654,75,6766,"0,0110848359",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,0,Damaging,"28,88","15,69"
"low bq, low freq, many artifacts, many samples",UPN2_084,X,15841334,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp473Ala/c.1418A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),8135,135,8299,"0,0162670201",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,0,Damaging,"28,84","15,05"
"low bq, low freq, many artifacts, many samples",UPN2_085,X,15841334,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp473Ala/c.1418A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),7902,108,8044,"0,0134261561",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,0,Damaging,"29,01","15,38"
"low bq, low freq, many artifacts, many samples",UPN2_086,X,15841334,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp473Ala/c.1418A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),11610,170,11835,"0,0143641741",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,0,Damaging,"28,8","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_087,X,15841334,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp473Ala/c.1418A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),6558,123,6697,"0,0183664327",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,0,Damaging,"29,27","15,8"
"low bq, low freq, many artifacts",UPN2_088,X,15841334,A,C,missense_variant(MODERATE|MISSENSE|gAc/gCc|p.Asp473Ala/c.1418A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),11359,127,11521,"0,0110233487",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,63",Neutral,0,Damaging,"29,93","15,36"
"low freq, many artifacts",UPN2_045,X,15841337,G,T,missense_variant(MODERATE|MISSENSE|aGa/aTa|p.Arg474Ile/c.1421G>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),1741,21,1763,"0,0119115145",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,97",Deleterious,"0,006",Damaging,"35,25","35,05"
"low bq, low freq, many artifacts, many samples",UPN2_060,X,15841338,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg474Ser/c.1422A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4287,81,4385,"0,0184720639",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,13,Damaging,"29,46","15,72"
"low bq, low freq, many artifacts, many samples",UPN2_061,X,15841338,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg474Ser/c.1422A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),11773,255,12099,"0,021076122",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,13,Damaging,"28,98","15,2"
"low bq, low freq, many artifacts, many samples",UPN2_062,X,15841338,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg474Ser/c.1422A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),5726,100,5850,"0,0170940171",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,13,Damaging,"28,71","14,84"
"low bq, low freq, many artifacts, many samples",UPN2_063,X,15841338,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg474Ser/c.1422A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),5450,102,5571,"0,0183091007",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,13,Damaging,"29,06","15,19"
"low bq, low freq, many artifacts, many samples",UPN2_064,X,15841338,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg474Ser/c.1422A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),1129,23,1157,"0,0198789974",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,13,Damaging,"28,45","15,74"
"low bq, low freq, many artifacts, many samples",UPN2_065,X,15841338,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg474Ser/c.1422A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2724,35,2770,"0,0126353791",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,13,Damaging,"29,23","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_066,X,15841338,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg474Ser/c.1422A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),7650,120,7796,"0,015392509",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,13,Damaging,"29,33","15,32"
"low bq, low freq, many artifacts, many samples",UPN2_067,X,15841338,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg474Ser/c.1422A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),9923,151,10121,"0,0149194744",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,13,Damaging,"29,66","15,11"
"low bq, low freq, many artifacts, many samples",UPN2_068,X,15841338,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg474Ser/c.1422A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),14282,309,14643,"0,0211022331",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,13,Damaging,"28,81","15,08"
"low bq, low freq, many artifacts, many samples",UPN2_069,X,15841338,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg474Ser/c.1422A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),6692,109,6845,"0,0159240321",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,13,Damaging,"28,95","14,86"
"low bq, many samples",UPN2_070,X,15841338,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg474Ser/c.1422A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),8884,216,9136,"0,023642732",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,13,Damaging,"28,57","14,82"
"low bq, low freq, many artifacts, many samples",UPN2_071,X,15841338,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg474Ser/c.1422A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),3286,51,3340,"0,0152694611",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,13,Damaging,"29,1","15,02"
"low bq, low freq, many artifacts, many samples",UPN2_072,X,15841338,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg474Ser/c.1422A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2178,43,2228,"0,0192998205",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,13,Damaging,"29,1","14,95"
"low bq, low freq, many artifacts, many samples",UPN2_074,X,15841338,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg474Ser/c.1422A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),6540,91,6656,"0,013671875",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,13,Damaging,"29,37","14,92"
"low bq, low freq, many artifacts, many samples",UPN2_075,X,15841338,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg474Ser/c.1422A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),5497,99,5623,"0,01760626",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,13,Damaging,"29,53","15,15"
"low bq, low freq, many artifacts, many samples",UPN2_076,X,15841338,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg474Ser/c.1422A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),5517,123,5661,"0,02172761",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,13,Damaging,"28,61","15,13"
"low bq, low freq, many artifacts, many samples",UPN2_077,X,15841338,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg474Ser/c.1422A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),6693,128,6842,"0,0187079801",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,13,Damaging,"28,98","15,21"
"low bq, low freq, many artifacts, many samples",UPN2_078,X,15841338,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg474Ser/c.1422A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),5556,115,5691,"0,0202073449",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,13,Damaging,"28,79","14,9"
"low bq, low freq, many artifacts, many samples",UPN2_079,X,15841338,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg474Ser/c.1422A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),6051,103,6182,"0,0166612747",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,13,Damaging,"29,29","15,01"
"low bq, low freq, many artifacts, many samples",UPN2_080,X,15841338,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg474Ser/c.1422A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2440,47,2494,"0,0188452285",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,13,Damaging,"28,96","17,04"
"low bq, low freq, many artifacts, many samples",UPN2_082,X,15841338,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg474Ser/c.1422A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),11261,187,11481,"0,0162877798",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,13,Damaging,"29,51","15,42"
"low bq, low freq, many artifacts, many samples",UPN2_083,X,15841338,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg474Ser/c.1422A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),6622,121,6766,"0,0178835353",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,13,Damaging,"28,63","14,74"
"low bq, low freq, many artifacts, many samples",UPN2_084,X,15841338,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg474Ser/c.1422A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),8114,156,8299,"0,0187974455",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,13,Damaging,"28,66","15,6"
"low bq, low freq, many artifacts, many samples",UPN2_085,X,15841338,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg474Ser/c.1422A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),7870,144,8043,"0,0179037673",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,13,Damaging,"28,93","15,12"
"low bq, low freq, many artifacts, many samples",UPN2_086,X,15841338,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg474Ser/c.1422A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),11548,228,11831,"0,0192714056",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,13,Damaging,"28,72","15,96"
"low bq, low freq, many artifacts, many samples",UPN2_087,X,15841338,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg474Ser/c.1422A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),6529,130,6696,"0,0194145759",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,13,Damaging,"29,01","15,64"
"low bq, low freq, many artifacts",UPN2_088,X,15841338,A,C,missense_variant(MODERATE|MISSENSE|agA/agC|p.Arg474Ser/c.1422A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),11298,167,11520,"0,0144965278",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,42",Neutral,13,Damaging,"29,73","15,75"
"low bq, low freq, many artifacts",UPN2_079,X,15841343,T,G,missense_variant(MODERATE|MISSENSE|gTt/gGt|p.Val476Gly/c.1427T>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),6194,63,6297,"0,0100047642",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,04",Neutral,6,Damaging,"30,94","15,63"
"low freq, many artifacts",UPN2_006,X,15841345,C,T,stop_gained(HIGH|NONSENSE|Cag/Tag|p.Gln477*/c.1429C>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),2678,32,2714,"0,0117907148",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,NA,NA,NA,NA,"34,06","33,88"
"low bq, low freq, many artifacts, many samples",UPN2_060,X,15841356,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys480Asn/c.1440A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),8552,97,8675,"0,0111815562",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,17",Neutral,26,Damaging,"27,63","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_061,X,15841356,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys480Asn/c.1440A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),23516,297,23929,"0,012411718",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,17",Neutral,26,Damaging,"27,25","14,25"
"low bq, low freq, many artifacts, many samples",UPN2_062,X,15841356,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys480Asn/c.1440A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),11369,142,11571,"0,0122720595",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,17",Neutral,26,Damaging,"27,18","14,46"
"low bq, low freq, many artifacts, many samples",UPN2_063,X,15841356,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys480Asn/c.1440A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),10856,129,11029,"0,0116964367",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,17",Neutral,26,Damaging,"27,54","14,16"
"low bq, low freq, many artifacts, many samples",UPN2_064,X,15841356,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys480Asn/c.1440A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),2231,39,2282,"0,0170902717",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,17",Neutral,26,Damaging,"27,41",14
"low bq, low freq, many artifacts, many samples",UPN2_065,X,15841356,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys480Asn/c.1440A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),5412,55,5481,"0,0100346652",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,17",Neutral,26,Damaging,"27,61","14,38"
"low bq, low freq, many artifacts, many samples",UPN2_066,X,15841356,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys480Asn/c.1440A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),15182,174,15433,"0,0112745416",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,17",Neutral,26,Damaging,"27,67","14,69"
"low bq, low freq, many artifacts, many samples",UPN2_067,X,15841356,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys480Asn/c.1440A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),19721,202,20015,"0,0100924307",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,17",Neutral,26,Damaging,"27,87","14,39"
"low bq, low freq, many artifacts, many samples",UPN2_068,X,15841356,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys480Asn/c.1440A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),28516,368,29004,"0,0126879051",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,17",Neutral,26,Damaging,"27,16","14,57"
"low bq, low freq, many artifacts, many samples",UPN2_069,X,15841356,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys480Asn/c.1440A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),13318,150,13530,"0,0110864745",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,17",Neutral,26,Damaging,"27,31","14,56"
"low freq, many artifacts, many samples",UPN2_070,X,15841356,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys480Asn/c.1440A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),17763,236,18063,"0,0130653823",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,17",Neutral,26,Damaging,27,"14,71"
"low bq, low freq, many artifacts, many samples",UPN2_071,X,15841356,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys480Asn/c.1440A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),6501,76,6606,"0,0115046927",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,17",Neutral,26,Damaging,"27,32","14,09"
"low bq, low freq, many artifacts, many samples",UPN2_072,X,15841356,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys480Asn/c.1440A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),4331,61,4409,"0,0138353368",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,17",Neutral,26,Damaging,"27,4","14,56"
"low bq, low freq, many artifacts, many samples",UPN2_075,X,15841356,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys480Asn/c.1440A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),10969,116,11126,"0,0104260291",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,17",Neutral,26,Damaging,"27,84","14,34"
"low bq, low freq, many artifacts, many samples",UPN2_076,X,15841356,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys480Asn/c.1440A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),11029,134,11212,"0,0119514806",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,17",Neutral,26,Damaging,"27,08","14,54"
"low bq, low freq, many artifacts, many samples",UPN2_077,X,15841356,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys480Asn/c.1440A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),13314,166,13543,"0,0122572547",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,17",Neutral,26,Damaging,"27,29","14,61"
"low bq, low freq, many artifacts, many samples",UPN2_078,X,15841356,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys480Asn/c.1440A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),11085,133,11264,"0,0118075284",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,17",Neutral,26,Damaging,"27,1","14,62"
"low bq, low freq, many artifacts, many samples",UPN2_079,X,15841356,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys480Asn/c.1440A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),12085,144,12264,"0,011741683",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,17",Neutral,26,Damaging,"27,41","14,44"
"low bq, low freq, many artifacts, many samples",UPN2_082,X,15841356,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys480Asn/c.1440A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),22362,242,22710,"0,0106560986",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,17",Neutral,26,Damaging,"27,72","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_083,X,15841356,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys480Asn/c.1440A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),13154,164,13390,"0,0122479462",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,17",Neutral,26,Damaging,"27,35","14,21"
"low bq, low freq, many artifacts, many samples",UPN2_084,X,15841356,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys480Asn/c.1440A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),16077,270,16426,"0,0164373554",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,17",Neutral,26,Damaging,"27,07","15,53"
"low bq, low freq, many artifacts, many samples",UPN2_085,X,15841356,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys480Asn/c.1440A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),15668,187,15918,"0,011747707",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,17",Neutral,26,Damaging,"27,25","14,55"
"low bq, low freq, many artifacts, many samples",UPN2_086,X,15841356,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys480Asn/c.1440A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),22982,312,23401,"0,0133327636",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,17",Neutral,26,Damaging,"27,09","14,59"
"low bq, low freq, many artifacts, many samples",UPN2_087,X,15841356,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys480Asn/c.1440A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),13066,157,13268,"0,0118329816",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,17",Neutral,26,Damaging,"27,4","15,54"
"low bq, low freq, many artifacts",UPN2_088,X,15841356,A,C,missense_variant(MODERATE|MISSENSE|aaA/aaC|p.Lys480Asn/c.1440A>C|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|C),22474,231,22798,"0,0101324678",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-1,17",Neutral,26,Damaging,"27,94","14,32"
"low freq, many artifacts",UPN2_006,X,15841361,A,G,missense_variant(MODERATE|MISSENSE|aAa/aGa|p.Lys482Arg/c.1445A>G|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|G),2678,32,2714,"0,0117907148",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"0,25",Neutral,0,Damaging,"33,8","35,75"
"low bq, low freq, many artifacts",UPN2_050,X,15841361,A,T,missense_variant(MODERATE|MISSENSE|aAa/aTa|p.Lys482Ile/c.1445A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),4456,48,4527,"0,0106030484",0,0,0,0,1,0,0,0,1,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-2,91",Deleterious,0,Damaging,"32,62","24,48"
"low bq, low freq, many artifacts",UPN2_044,X,15841362,A,T,missense_variant(MODERATE|MISSENSE|aaA/aaT|p.Lys482Asn/c.1446A>T|482|ZRSR2|protein_coding|CODING|ENST00000307771|11|T),3984,55,4066,"0,0135268077",0,0,0,0,1,0,0,1,2,NO,NO,NO,NO,O,NO,NO,NO,NO,NO,NO,"-0,83",Neutral,0,Damaging,"32,68","28,95"
,,,,,,,,,,,209,791,109,1650,35126,4389,111,3517,,,,,,,,,,,,,,,,,,